-- dump date 20140619_043104 -- class Genbank::misc_feature -- table misc_feature_note -- id note 413999000001 chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149 413999000002 DnaA N-terminal domain; Region: DnaA_N; pfam11638 413999000003 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999000004 Walker A motif; other site 413999000005 ATP binding site [chemical binding]; other site 413999000006 Walker B motif; other site 413999000007 arginine finger; other site 413999000008 C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571 413999000009 DnaA box-binding interface [nucleotide binding]; other site 413999000010 Pfam match to entry PF00308 bac_dnaA, Bacterial dnaA protein, score 706.0, E-value 1.9e-209 413999000011 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000012 PS01008 DnaA protein signature. 413999000013 DNA polymerase III subunit beta; Validated; Region: PRK05643 413999000014 Beta clamp domain. The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140 413999000015 putative DNA binding surface [nucleotide binding]; other site 413999000016 dimer interface [polypeptide binding]; other site 413999000017 beta-clamp/clamp loader binding surface; other site 413999000018 beta-clamp/translesion DNA polymerase binding surface; other site 413999000019 Pfam match to entry PF00712 DNA_pol3_beta, DNA polymerase III beta subunit, N-terminal domain, score 131.7, E-value 1.4e-36 413999000020 Pfam match to entry PF02767 DNA_pol3_beta_2, DNA polymerase III beta subunit, central domain, score 119.4,E-value 7.1e-33 413999000021 Pfam match to entry PF02768 DNA_pol3_beta_3, DNA polymerase III beta subunit, C-terminal domain, score 126.9, E-value 3.8e-35 413999000022 S4 domain; Region: S4_2; pfam13275 413999000023 Pfam match to entry PF01479 S4, S4 domain, score 29.5, E-value 8.4e-06 413999000024 recombination protein F; Reviewed; Region: recF; PRK00064 413999000025 ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242 413999000026 Walker A/P-loop; other site 413999000027 ATP binding site [chemical binding]; other site 413999000028 Q-loop/lid; other site 413999000029 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999000030 ABC transporter signature motif; other site 413999000031 Walker B; other site 413999000032 D-loop; other site 413999000033 H-loop/switch region; other site 413999000034 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain, score 20.6, E-value 9.8e-06 413999000035 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000036 DNA gyrase subunit B; Validated; Region: gyrB; PRK05644 413999000037 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999000038 Mg2+ binding site [ion binding]; other site 413999000039 G-X-G motif; other site 413999000040 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 413999000041 anchoring element; other site 413999000042 dimer interface [polypeptide binding]; other site 413999000043 ATP binding site [chemical binding]; other site 413999000044 TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366 413999000045 active site 413999000046 putative metal-binding site [ion binding]; other site 413999000047 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 413999000048 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 115.1, E-value 1.4e-31 413999000049 Pfam match to entry PF00204 DNA_gyraseB, DNA gyrase B, score 318.9, E-value 6.2e-93 413999000050 Pfam match to entry PF01751 Toprim, Toprim domain,score 26.6, E-value 6e-05 413999000051 PS00177 DNA topoisomerase II signature. 413999000052 PS00687 Aldehyde dehydrogenases glutamic acid active site. 413999000053 Pfam match to entry PF00986 DNA_gyraseB_C, DNA gyrase B subunit, carboxyl terminus, score 169.7, E-value 5.1e-48 413999000054 DNA gyrase subunit A; Validated; Region: PRK05560 413999000055 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 413999000056 CAP-like domain; other site 413999000057 active site 413999000058 primary dimer interface [polypeptide binding]; other site 413999000059 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999000060 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999000061 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999000062 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999000063 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999000064 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999000065 Pfam match to entry PF00521 DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A, score 1052.5, E-value 0 413999000066 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 51.3,E-value 2.2e-12 413999000067 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 55.1,E-value 1.6e-13 413999000068 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 43.8,E-value 4.1e-10 413999000069 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 67.8,E-value 2.3e-17 413999000070 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 52.1,E-value 1.3e-12 413999000071 PS00572 Glycosyl hydrolases family 1 active site. 413999000072 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 55.3,E-value 1.4e-13 413999000073 Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827 413999000074 HTH domain; Region: HTH_11; pfam08279 413999000075 3H domain; Region: 3H; pfam02829 413999000076 Pfam match to entry PF02829 3H, 3H domain, score 82.3, E-value 1.1e-21 413999000077 Uncharacterized conserved protein [Function unknown]; Region: COG2006 413999000078 Domain of unknown function (DUF362); Region: DUF362; pfam04015 413999000079 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999000080 4Fe-4S dicluster domain; Region: Fer4_9; pfam13187 413999000081 Pfam match to entry PF04015 DUF362, Domain of unknown function (DUF362), score 107.5, E-value 2.6e-29 413999000082 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 27.0, E-value 1.4e-05 413999000083 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000084 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 23.4, E-value 5.2e-05 413999000085 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000086 hypothetical protein; Validated; Region: PRK00068 413999000087 Uncharacterized conserved protein [Function unknown]; Region: COG1615 413999000088 Pfam match to entry PF03699 UPF0182,Uncharacterised protein family (UPF0182), score 1042.4,E-value 0 413999000089 7 probable transmembrane helices predicted for CBO0011 by TMHMM2.0 at aa 7-29, 49-68, 94-116, 151-173,202-224, 244-266 and 273-295 413999000090 Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376 413999000091 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 413999000092 Pfam match to entry PF03734 ErfK_YbiS_YhnG,ErfK/YbiS/YcfS/YnhG, score 56.8, E-value 4.8e-14 413999000093 Predicted dehydrogenase [General function prediction only]; Region: COG0579 413999000094 hydroxyglutarate oxidase; Provisional; Region: PRK11728 413999000095 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 413999000096 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999000097 Pfam match to entry PF04324 fer2_BFD, BFD-like [2Fe-2S] binding domain, score 82.8, E-value 7.1e-22 413999000098 Protein of unknown function (DUF1667); Region: DUF1667; pfam07892 413999000099 seryl-tRNA synthetase; Provisional; Region: PRK05431 413999000100 Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403 413999000101 Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770 413999000102 dimer interface [polypeptide binding]; other site 413999000103 active site 413999000104 motif 1; other site 413999000105 motif 2; other site 413999000106 motif 3; other site 413999000107 Pfam match to entry PF02403 Seryl_tRNA_N,Seryl-tRNA synthetase N-terminal domain, score 55.9,E-value 8.9e-14 413999000108 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score 209.9, E-value 4.1e-60 413999000109 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999000110 Pfam match to entry PF02666 PS_Dcarbxylase,Phosphatidylserine decarboxylase, score 218.5, E-value 1e-62 413999000111 1 probable transmembrane helix predicted for CBO0020 by TMHMM2.0 at aa 7-29 413999000112 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 413999000113 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999000114 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999000115 Walker A/P-loop; other site 413999000116 ATP binding site [chemical binding]; other site 413999000117 Q-loop/lid; other site 413999000118 ABC transporter signature motif; other site 413999000119 Walker B; other site 413999000120 D-loop; other site 413999000121 H-loop/switch region; other site 413999000122 Pfam match to entry PF00005 ABC_tran, ABC transporter score 152.8, E-value 6.3e-43 413999000123 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000124 PS00211 ABC transporters family signature. 413999000125 6 probable transmembrane helices predicted for CBO0022 by TMHMM2.0 at aa 20-42, 57-79, 100-131, 151-173,175-197 and 246-268 413999000126 6 probable transmembrane helices predicted for CBO0023 by TMHMM2.0 at aa 16-35, 63-85, 113-135, 165-184,197-216 and 243-262 413999000127 6 probable transmembrane helices predicted for CBO0024 by TMHMM2.0 at aa 13-35, 68-90, 118-140, 165-187,200-222 and 237-259 413999000128 phosphatidylserine decarboxylase; Provisional; Region: PRK00723 413999000129 Pfam match to entry PF02666 PS_Dcarbxylase,Phosphatidylserine decarboxylase, score 226.0, E-value 5.7e-65 413999000130 2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982 413999000131 ABC1 family; Region: ABC1; cl17513 413999000132 2 probable transmembrane helices predicted for CBO0026 by TMHMM2.0 at aa 476-498 and 505-527 413999000133 Pfam match to entry PF03109 ABC1, ABC1 family,score 108.2, E-value 1.7e-29 413999000134 Uncharacterized conserved protein [Function unknown]; Region: COG3937 413999000135 Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism]; Region: TyrR; COG3283 413999000136 ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141 413999000137 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999000138 Walker A motif; other site 413999000139 ATP binding site [chemical binding]; other site 413999000140 Walker B motif; other site 413999000141 arginine finger; other site 413999000142 Pfam match to entry PF01842 ACT, ACT domain, score 20.7, E-value 0.0036 413999000143 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 409.7, E-value 2.9e-120 413999000144 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999000145 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999000146 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999000147 Predicted helix-turn-helix motif with score 1652.000, SD 4.81 at aa 484-505, sequence KSLRKVGKVLGVSHTTVMNKIK 413999000148 methionine gamma-lyase; Provisional; Region: PRK06234 413999000149 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 413999000150 homodimer interface [polypeptide binding]; other site 413999000151 substrate-cofactor binding pocket; other site 413999000152 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999000153 catalytic residue [active] 413999000154 Pfam match to entry PF01053 Cys_Met_Meta_PP,Cys/Met metabolism PLP-dependent enzyme, score 774.1,E-value 5.9e-230 413999000155 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 413999000156 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 413999000157 nucleoside/Zn binding site; other site 413999000158 dimer interface [polypeptide binding]; other site 413999000159 catalytic motif [active] 413999000160 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region, score 115.8, E-value 8.3e-32 413999000161 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 413999000162 DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563 413999000163 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999000164 Walker A motif; other site 413999000165 ATP binding site [chemical binding]; other site 413999000166 Walker B motif; other site 413999000167 arginine finger; other site 413999000168 DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169 413999000169 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 51.6, E-value 1.9e-12 413999000170 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000171 hypothetical protein; Validated; Region: PRK00153 413999000172 Pfam match to entry PF02575 DUF149, Uncharacterised BCR, YbaB family COG0718, score 150.9, E-value 2.3e-42 413999000173 recombination protein RecR; Reviewed; Region: recR; PRK00076 413999000174 RecR protein; Region: RecR; pfam02132 413999000175 TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR. RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025 413999000176 putative active site [active] 413999000177 putative metal-binding site [ion binding]; other site 413999000178 tetramer interface [polypeptide binding]; other site 413999000179 Pfam match to entry PF02132 RecR, RecR protein,score 67.6, E-value 2.7e-17 413999000180 PS01300 RecR protein signature. 413999000181 Pfam match to entry PF01751 Toprim, Toprim domain,score 72.8, E-value 7.3e-19 413999000182 Protein of unknown function (DUF2508); Region: DUF2508; pfam10704 413999000183 pro-sigmaK processing inhibitor BofA; Region: spore_BofA; TIGR02862 413999000184 3 probable transmembrane helices predicted for CBO0035 by TMHMM2.0 at aa 5-27, 31-53 and 60-82 413999000185 putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347 413999000186 Pfam match to entry PF03749 SfsA, Sugar fermentation stimulation protein, score 255.5, E-value 7.6e-74 413999000187 NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429 413999000188 putative NADH binding site [chemical binding]; other site 413999000189 putative active site [active] 413999000190 nudix motif; other site 413999000191 putative metal binding site [ion binding]; other site 413999000192 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 50.3, E-value 4.4e-12 413999000193 PS00893 mutT domain signature. 413999000194 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 413999000195 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 413999000196 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999000197 4Fe-4S dicluster domain; Region: Fer4_9; pfam13187 413999000198 PS00201 Flavodoxin signature. 413999000199 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 23.5, E-value 5.1e-05 413999000200 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000201 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 24.6, E-value 3.3e-05 413999000202 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000203 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179 413999000204 Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755 413999000205 putative ATP binding site [chemical binding]; other site 413999000206 putative substrate interface [chemical binding]; other site 413999000207 Pfam match to entry PF00899 ThiF, ThiF family,score 150.1, E-value 4.2e-42 413999000208 Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738 413999000209 11 probable transmembrane helices predicted for CBO0041 by TMHMM2.0 at aa 4-26, 37-59, 74-96, 103-125,156-178, 198-220, 235-257, 262-284, 288-310, 319-341 and 346-368 413999000210 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 413999000211 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 413999000212 Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030 413999000213 active site 413999000214 Fe-S cluster binding site [ion binding]; other site 413999000215 RNA polymerase factor sigma-70; Validated; Region: PRK06811 413999000216 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999000217 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999000218 DNA binding residues [nucleotide binding] 413999000219 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 26.4, E-value 6.8e-05 413999000220 Domain of unknown function (DUF4179); Region: DUF4179; pfam13786 413999000221 1 probable transmembrane helix predicted for CBO0043 by TMHMM2.0 at aa 62-84 413999000222 D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092 413999000223 SurA N-terminal domain; Region: SurA_N_3; cl07813 413999000224 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 413999000225 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain, score 111.1, E-value 2.3e-30 413999000226 PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 413999000227 NAD-dependent deacetylase; Provisional; Region: PRK00481 413999000228 SIR2 family of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2-fam; cd01407 413999000229 NAD+ binding site [chemical binding]; other site 413999000230 substrate binding site [chemical binding]; other site 413999000231 Zn binding site [ion binding]; other site 413999000232 Pfam match to entry PF02146 SIR2, Sir2 family,score 231.9, E-value 9.9e-67 413999000233 LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025 413999000234 dimer interface [polypeptide binding]; other site 413999000235 catalytic triad [active] 413999000236 Pfam match to entry PF02016 Peptidase_U61,LD-carboxypeptidase, score 110.0, E-value 4.9e-30 413999000237 Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598 413999000238 uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827 413999000239 Cl binding site [ion binding]; other site 413999000240 oligomer interface [polypeptide binding]; other site 413999000241 Pfam match to entry PF01544 CorA, CorA-like Mg2+ transporter protein, score 20.8, E-value 6.2e-09 413999000242 2 probable transmembrane helices predicted for CBO0050 by TMHMM2.0 at aa 251-273 and 288-307 413999000243 2 probable transmembrane helices predicted for CBO0051 by TMHMM2.0 at aa 13-32 and 47-65 413999000244 M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672 413999000245 amidohydrolase; Region: amidohydrolases; TIGR01891 413999000246 metal binding site [ion binding]; metal-binding site 413999000247 Inhibitor of sigma-G Gin; Region: Gin; pfam10764 413999000248 Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982 413999000249 Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615 413999000250 homodimer interface [polypeptide binding]; other site 413999000251 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999000252 catalytic residue [active] 413999000253 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 413999000254 Pfam match to entry PF01276 OKR_DC_1, Orn/Lys/Arg decarboxylase, major domain, score 228.0, E-value 1.4e-65 413999000255 Predicted helix-turn-helix motif with score 984.000, SD 2.54 at aa 327-348, sequence LTRYTINIKNGLNANCLSKYLR 413999000256 Pfam match to entry PF03711 OKR_DC_1_C, Orn/Lys/Arg decarboxylase, C-terminal domain, score -4.1, E-value 0.00071 413999000257 thymidylate kinase; Provisional; Region: PRK13975; cl17243 413999000258 Pfam match to entry PF02223 Thymidylate_kin,Thymidylate kinase, score 11.7, E-value 1.6e-05 413999000259 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999000260 Protein of unknown function (DUF970); Region: DUF970; pfam06153 413999000261 Pfam match to entry PF06153 DUF970, Protein of unknown function (DUF970), score 237.2, E-value 2.5e-68 413999000262 DNA polymerase III subunit delta'; Validated; Region: PRK05564 413999000263 DNA polymerase III subunit delta'; Validated; Region: PRK08485 413999000264 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000265 Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774 413999000266 Pfam match to entry PF04468 PSP1, PSP1 C-terminal region, score 187.2, E-value 2.8e-53 413999000267 Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608 413999000268 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 11.0, E-value 0.071 413999000269 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999000270 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 413999000271 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 34.4, E-value 2.8e-07 413999000272 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000273 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 33.1, E-value 6.9e-07 413999000274 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000275 Predicted O-methyltransferase [General function prediction only]; Region: COG4123 413999000276 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999000277 S-adenosylmethionine binding site [chemical binding]; other site 413999000278 Predicted methyltransferases [General function prediction only]; Region: COG0313 413999000279 Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648 413999000280 putative SAM binding site [chemical binding]; other site 413999000281 putative homodimer interface [polypeptide binding]; other site 413999000282 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 149.7,E-value 5.3e-42 413999000283 PS01296 Uncharacterized protein family UPF0011 signature. 413999000284 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883 413999000285 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 413999000286 NlpC/P60 family; Region: NLPC_P60; pfam00877 413999000287 Pfam match to entry PF00877 NLPC_P60, NlpC/P60 family, score 171.2, E-value 1.8e-48 413999000288 Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002 413999000289 SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966 413999000290 Pfam match to entry PF04014 SpoVT_AbrB, SpoVT / AbrB like domain, score 58.0, E-value 2.2e-14 413999000291 Domain of unknown function (DUF1836); Region: DUF1836; pfam08876 413999000292 arginine deiminase; Provisional; Region: PRK01388 413999000293 Pfam match to entry PF02274 Amidinotransf,Amidinotransferase, score 570.6, E-value 1.1e-168 413999000294 MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554 413999000295 homotrimer interaction site [polypeptide binding]; other site 413999000296 zinc binding site [ion binding]; other site 413999000297 CDP-binding sites; other site 413999000298 Pfam match to entry PF02542 YgbB, YgbB family,score 271.4, E-value 1.3e-78 413999000299 PS00294 Prenyl group binding site (CAAX box). 413999000300 1 probable transmembrane helix predicted for CBO0067 by TMHMM2.0 at aa 22-44 413999000301 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 413999000302 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 413999000303 putative active site [active] 413999000304 putative metal binding site [ion binding]; other site 413999000305 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999000306 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 148.1, E-value 1.6e-41 413999000307 Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715 413999000308 Pfam match to entry PF04291 Spore_mat_A, Spore maturation protein A, score 321.3, E-value 1.2e-93 413999000309 5 probable transmembrane helices predicted for CBO0070 by TMHMM2.0 at aa 4-23, 36-58, 90-112, 133-155 and 165-187 413999000310 Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700 413999000311 5 probable transmembrane helices predicted for CBO0071 by TMHMM2.0 at aa 3-22, 37-59, 78-100, 120-142 and 149-171 413999000312 Pfam match to entry PF03751 Spore_mat_B, Spore maturation protein B, score 208.8, E-value 8.8e-60 413999000313 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999000314 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137 413999000315 10 probable transmembrane helices predicted for CBO0072 by TMHMM2.0 at aa 12-31, 55-77, 90-112, 127-149,162-184, 194-216, 320-342, 362-384, 391-413 and 417-439 413999000316 Pfam match to entry PF01554 MatE, MatE, score 151.7, E-value 1.3e-42 413999000317 Pfam match to entry PF01554 MatE, MatE, score 119.7, E-value 5.9e-33 413999000318 Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030 413999000319 Fe-S cluster binding site [ion binding]; other site 413999000320 active site 413999000321 Pfam match to entry PF03167 UDG, Uracil DNA glycosylase superfamily, score 92.8, E-value 7.1e-25 413999000322 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999000323 MarR family; Region: MarR_2; cl17246 413999000324 Pfam match to entry PF01047 MarR, MarR family,score 65.4, E-value 1.3e-16 413999000325 Predicted helix-turn-helix motif with score 1182.000, SD 3.21 at aa 50-71, sequence ITLKKLSTYICVSTSSLCIMLT 413999000326 methionyl-tRNA synthetase; Reviewed; Region: PRK12267 413999000327 catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814 413999000328 active site 413999000329 HIGH motif; other site 413999000330 KMSKS motif; other site 413999000331 Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957 413999000332 anticodon binding site; other site 413999000333 tRNA binding surface [nucleotide binding]; other site 413999000334 tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800 413999000335 dimer interface [polypeptide binding]; other site 413999000336 putative tRNA-binding site [nucleotide binding]; other site 413999000337 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V), score -113.3, E-value 7.3e-10 413999000338 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999000339 Pfam match to entry PF01588 tRNA_bind, tRNA binding domain, score 160.3, E-value 3.5e-45 413999000340 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399 413999000341 2 probable transmembrane helices predicted for CBO0076 by TMHMM2.0 at aa 3-22 and 479-498 413999000342 Pfam match to entry PF04286 DUF445, Protein of unknown function (DUF445), score 82.7, E-value 7.7e-22 413999000343 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 413999000344 active site 413999000345 Pfam match to entry PF01026 TatD_DNase, TatD related DNase, score 389.4, E-value 3.7e-114 413999000346 1 probable transmembrane helix predicted for CBO0078 by TMHMM2.0 at aa 18-40 413999000347 Domain of unknown function (DUF348); Region: DUF348; pfam03990 413999000348 Domain of unknown function (DUF348); Region: DUF348; pfam03990 413999000349 G5 domain; Region: G5; pfam07501 413999000350 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584 413999000351 1 probable transmembrane helix predicted for CBO0079 by TMHMM2.0 at aa 12-34 413999000352 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999000353 Pfam match to entry PF03990 DUF348, Domain of unknown function (DUF348), score 35.7, E-value 1.1e-07 413999000354 Pfam match to entry PF03990 DUF348, Domain of unknown function (DUF348), score 46.3, E-value 7e-11 413999000355 ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334 413999000356 TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea. RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027 413999000357 putative active site [active] 413999000358 putative metal binding site [ion binding]; other site 413999000359 Domain of unknown function (DUF4093); Region: DUF4093; pfam13331 413999000360 Pfam match to entry PF01751 Toprim, Toprim domain,score 43.2, E-value 6.2e-10 413999000361 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274 413999000362 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999000363 S-adenosylmethionine binding site [chemical binding]; other site 413999000364 Pfam match to entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylase, score 281.6, E-value 1e-81 413999000365 PS01131 Ribosomal RNA adenine dimethylases signature. 413999000366 1 probable transmembrane helix predicted for CBO0083 by TMHMM2.0 at aa 13-30 413999000367 1 probable transmembrane helix predicted for CBO0084 by TMHMM2.0 at aa 7-24 413999000368 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999000369 Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999 413999000370 HlyD family secretion protein; Region: HlyD_3; pfam13437 413999000371 1 probable transmembrane helix predicted for CBO0085 by TMHMM2.0 at aa 7-24 413999000372 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999000373 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999000374 Walker A/P-loop; other site 413999000375 ATP binding site [chemical binding]; other site 413999000376 Q-loop/lid; other site 413999000377 ABC transporter signature motif; other site 413999000378 Walker B; other site 413999000379 D-loop; other site 413999000380 H-loop/switch region; other site 413999000381 Pfam match to entry PF00005 ABC_tran, ABC transporter score 197.5, E-value 2.2e-56 413999000382 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000383 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999000384 PS00211 ABC transporters family signature. 413999000385 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 413999000386 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999000387 FtsX-like permease family; Region: FtsX; pfam02687 413999000388 4 probable transmembrane helices predicted for CBO0087 by TMHMM2.0 at aa 21-40, 272-294, 331-353 and 363-385 413999000389 Pfam match to entry PF02687 FtsX, Predicted permease, score 150.1, E-value 4.1e-42 413999000390 MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037 413999000391 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000392 PS01215 Mrp family signature. 413999000393 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999000394 4Fe-4S single cluster domain; Region: Fer4_15; pfam13459 413999000395 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 11.5, E-value 0.0039 413999000396 1 probable transmembrane helix predicted for CBO0090 by TMHMM2.0 at aa 15-35 413999000397 FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203 413999000398 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999000399 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999000400 metal binding site [ion binding]; metal-binding site 413999000401 active site 413999000402 I-site; other site 413999000403 1 probable transmembrane helix predicted for CBO0092 by TMHMM2.0 at aa 2-24 413999000404 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 141.5, E-value 1.6e-39 413999000405 Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285 413999000406 MgtC family; Region: MgtC; pfam02308 413999000407 4 probable transmembrane helices predicted for CBO0093 by TMHMM2.0 at aa 5-22, 35-57, 77-95 and 108-130 413999000408 Pfam match to entry PF02308 MgtC, MgtC family,score 130.5, E-value 3.2e-36 413999000409 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999000410 anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111 413999000411 ATP cone domain; Region: ATP-cone; pfam03477 413999000412 Class III ribonucleotide reductase; Region: RNR_III; cd01675 413999000413 effector binding site; other site 413999000414 active site 413999000415 Zn binding site [ion binding]; other site 413999000416 glycine loop; other site 413999000417 Pfam match to entry PF03477 ATP-cone, ATP cone domain, score 79.2, E-value 8.6e-21 413999000418 4Fe-4S single cluster domain; Region: Fer4_12; pfam13353 413999000419 anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804 413999000420 PS01087 Radical activating enzymes signature. 413999000421 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 8.3, E-value 0.063 413999000422 MSEP-CTERM protein; Region: MSEP-CTERM; TIGR04286 413999000423 4 probable transmembrane helices predicted for CBO0096 by TMHMM2.0 at aa 95-117, 132-154, 167-186 and 199-221 413999000424 Predicted transcriptional regulators [Transcription]; Region: COG1695 413999000425 Transcriptional regulator PadR-like family; Region: PadR; pfam03551 413999000426 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family, score 102.3, E-value 9.7e-28 413999000427 Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220 413999000428 Beta-lactamase superfamily domain; Region: Lactamase_B_3; pfam13483 413999000429 isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039 413999000430 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 413999000431 HIGH motif; other site 413999000432 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 413999000433 active site 413999000434 KMSKS motif; other site 413999000435 Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961 413999000436 tRNA binding surface [nucleotide binding]; other site 413999000437 anticodon binding site; other site 413999000438 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V), score 845.2, E-value 2.4e-251 413999000439 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999000440 PS00307 Legume lectins beta-chain signature. 413999000441 Transcriptional regulators [Transcription]; Region: PurR; COG1609 413999000442 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 413999000443 DNA binding site [nucleotide binding] 413999000444 domain linker motif; other site 413999000445 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 413999000446 Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score 41.5, E-value 2e-09 413999000447 Predicted helix-turn-helix motif with score 1870.000, SD 5.56 at aa 3-24, sequence VSIKDVAKEAQVSIATVSRVLN 413999000448 PS00356 Bacterial regulatory proteins, lacI family signature. 413999000449 Pfam match to entry PF00532 Peripla_BP_like,Periplasmic binding proteins and sugar binding domain of the LacI family, score 121.2, E-value 2e-33 413999000450 AAA domain; Region: AAA_11; pfam13086 413999000451 Part of AAA domain; Region: AAA_19; pfam13245 413999000452 Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112 413999000453 AAA domain; Region: AAA_12; pfam13087 413999000454 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000455 Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836 413999000456 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 413999000457 Substrate binding site; other site 413999000458 Cupin domain; Region: Cupin_2; cl17218 413999000459 Pfam match to entry PF00483 NTP_transferase,Nucleotidyl transferase, score 194.3, E-value 1.9e-55 413999000460 Pfam match to entry PF01050 MannoseP_isomer,Mannose-6-phosphate isomerase, score 39.8, E-value 5.4e-10 413999000461 hypothetical protein; Provisional; Region: PRK04194 413999000462 Pfam match to entry PF01969 DUF111, Protein of unknown function DUF111, score 382.4, E-value 4.7e-112 413999000463 ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606 413999000464 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_I; cd01990 413999000465 Ligand Binding Site [chemical binding]; other site 413999000466 NCAIR mutase (PurE)-related proteins [General function prediction only]; Region: COG1691 413999000467 AIR carboxylase; Region: AIRC; smart01001 413999000468 Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729 413999000469 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999000470 FeS/SAM binding site; other site 413999000471 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 79.0, E-value 1e-20 413999000472 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 413999000473 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 28.8, E-value 1.3e-05 413999000474 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 413999000475 glycosyltransferase, GG-Bacteroidales peptide system; Region: glyco_rSAM_CFB; TIGR04157 413999000476 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 135.9, E-value 7.8e-38 413999000477 spore coat protein, CotS family; Region: spore_CotS; TIGR02906 413999000478 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 413999000479 substrate binding site [chemical binding]; other site 413999000480 PS00109 Tyrosine protein kinases specific active-site signature. 413999000481 spore coat protein, CotS family; Region: spore_CotS; TIGR02906 413999000482 spore coat protein, CotS family; Region: spore_CotS; TIGR02906 413999000483 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 413999000484 substrate binding site [chemical binding]; other site 413999000485 PS00109 Tyrosine protein kinases specific active-site signature. 413999000486 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999000487 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 413999000488 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 164.8, E-value 1.6e-46 413999000489 spore coat protein, CotS family; Region: spore_CotS; TIGR02906 413999000490 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 413999000491 active site 413999000492 ATP binding site [chemical binding]; other site 413999000493 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 413999000494 substrate binding site [chemical binding]; other site 413999000495 PS00109 Tyrosine protein kinases specific active-site signature. 413999000496 YabG peptidase U57; Region: Peptidase_U57; pfam05582 413999000497 Pfam match to entry PF05582 Peptidase_U57, YabG peptidase U57, score 596.9, E-value 1.3e-176 413999000498 Protein of unknown function (DUF1021); Region: DUF1021; pfam06257 413999000499 Pfam match to entry PF06257 DUF1021, Protein of unknown function (DUF1021), score 143.9, E-value 3e-40 413999000500 Domain of unknown function (DUF3794); Region: DUF3794; pfam12673 413999000501 Domain of unknown function (DUF3794); Region: DUF3794; pfam12673 413999000502 Domain of unknown function (DUF3794); Region: DUF3794; pfam12673 413999000503 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999000504 Pfam match to entry PF01476 LysM, LysM domain,score 73.5, E-value 4.7e-19 413999000505 Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145 413999000506 proposed catalytic triad [active] 413999000507 active site nucleophile [active] 413999000508 Pfam match to entry PF03575 Peptidase_S51,Peptidase S51, score 244.5, E-value 1.6e-70 413999000509 cyanophycin synthetase; Provisional; Region: PRK14016 413999000510 ATP-grasp domain; Region: ATP-grasp_4; cl17255 413999000511 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999000512 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 413999000513 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000514 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 126.5, E-value 5.2e-35 413999000515 PS01011 Folylpolyglutamate synthase signature 1. 413999000516 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain, score 46.8,E-value 5.1e-11 413999000517 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128 413999000518 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 413999000519 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein, score 107.5, E-value 2.8e-29 413999000520 2 probable transmembrane helices predicted for CBO0122 by TMHMM2.0 at aa 11-28 and 43-60 413999000521 Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323 413999000522 Pfam match to entry PF03323 GerA,Bacillus/Clostridium GerA spore germination protein, score 714.1, E-value 6.6e-212 413999000523 4 probable transmembrane helices predicted for CBO0123 by TMHMM2.0 at aa 306-328, 370-389, 394-416 and 431-453 413999000524 Spore germination protein; Region: Spore_permease; cl17796 413999000525 Pfam match to entry PF03845 Spore_permease, Spore germination protein, score 160.8, E-value 2.4e-45 413999000526 10 probable transmembrane helices predicted for CBO0124 by TMHMM2.0 at aa 7-29, 42-64, 85-107, 117-134,147-169, 184-206, 218-240, 270-292, 304-321 and 336-355 413999000527 germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887 413999000528 Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504 413999000529 Pfam match to entry PF05504 Spore_GerAC, Spore germination B3/ GerAC like, C-terminal, score 120.7,E-value 2.8e-33 413999000530 Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; pfam09551 413999000531 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane]; Region: MurG; COG0707 413999000532 Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925 413999000533 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 413999000534 germination protein YpeB; Region: spore_YpeB; TIGR02889 413999000535 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482 413999000536 ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712 413999000537 Ligand Binding Site [chemical binding]; other site 413999000538 Domain of unknown function (DUF814); Region: DUF814; pfam05670 413999000539 PS00190 Cytochrome c family heme-binding site signature. 413999000540 Domain of unknown function (DUF1934); Region: DUF1934; pfam09148 413999000541 CTP synthetase; Validated; Region: pyrG; PRK05380 413999000542 CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113 413999000543 Catalytic site [active] 413999000544 active site 413999000545 UTP binding site [chemical binding]; other site 413999000546 Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746 413999000547 active site 413999000548 putative oxyanion hole; other site 413999000549 catalytic triad [active] 413999000550 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I, score 280.0, E-value 3.3e-81 413999000551 PS00442 Glutamine amidotransferases class-I active site. 413999000552 transcription termination factor Rho; Provisional; Region: rho; PRK09376 413999000553 Rho termination factor, N-terminal domain; Region: Rho_N; smart00959 413999000554 Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459 413999000555 RNA binding site [nucleotide binding]; other site 413999000556 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 413999000557 Walker A motif; other site 413999000558 ATP binding site [chemical binding]; other site 413999000559 Walker B motif; other site 413999000560 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000561 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain,score 106.3, E-value 6.2e-29 413999000562 50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019 413999000563 Pfam match to entry PF01197 Ribosomal_L31,Ribosomal protein L31, score 144.8, E-value 1.6e-40 413999000564 PS01143 Ribosomal protein L31 signature. 413999000565 PS00190 Cytochrome c family heme-binding site signature. 413999000566 thymidine kinase; Provisional; Region: PRK04296 413999000567 Pfam match to entry PF00265 TK, Thymidine kinase,score 291.8, E-value 8.6e-85 413999000568 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000569 PS00603 Thymidine kinase cellular-type signature. 413999000570 PS00190 Cytochrome c family heme-binding site signature. 413999000571 Protein of unknown function (DUF1385); Region: DUF1385; pfam07136 413999000572 4 probable transmembrane helices predicted for CBO0137 by TMHMM2.0 at aa 49-71, 107-129, 141-163 and 210-232 413999000573 protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534 413999000574 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999000575 PS00092 N-6 Adenine-specific DNA methylases signature. 413999000576 peptide chain release factor 1; Validated; Region: prfA; PRK00591 413999000577 This domain is found in peptide chain release factors; Region: PCRF; smart00937 413999000578 RF-1 domain; Region: RF-1; pfam00472 413999000579 Pfam match to entry PF03462 PCRF, PCRF domain,score 243.9, E-value 2.4e-70 413999000580 Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain, score 263.4, E-value 3.2e-76 413999000581 PS00745 Prokaryotic-type class I peptide chain release factors signature. 413999000582 2 probable transmembrane helices predicted for CBO0140 by TMHMM2.0 at aa 13-35 and 41-60 413999000583 Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428 413999000584 Pfam match to entry PF02535 Zip, ZIP Zinc transporter score 75.3, E-value 1.3e-19 413999000585 7 probable transmembrane helices predicted for CBO0141 by TMHMM2.0 at aa 5-27, 42-61, 66-83, 98-120,162-184, 188-206 and 219-236 413999000586 Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009 413999000587 Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481 413999000588 Pfam match to entry PF01300 Sua5_yciO_yrdC, yrdC domain, score 230.4, E-value 2.8e-66 413999000589 PS01147 SUA5/yciO/yrdC family signature. 413999000590 Pfam match to entry PF03481 SUA5, SUA5 domain,score 204.2, E-value 2e-58 413999000591 Low molecular weight phosphatase family; Region: LMWPc; cd00115 413999000592 Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451 413999000593 active site 413999000594 Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase, score 85.8,E-value 9.3e-23 413999000595 ribose-5-phosphate isomerase B; Provisional; Region: PRK05571 413999000596 Pfam match to entry PF02502 LacAB_rpiB,Ribose/Galactose Isomerase, score 170.3, E-value 3.3e-48 413999000597 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999000598 active site 413999000599 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 46.3, E-value 7.3e-11 413999000600 Deoxycytidylate deaminase [Nucleotide transport and metabolism]; Region: ComEB; COG2131 413999000601 active site 413999000602 Zn binding site [ion binding]; other site 413999000603 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region, score 69.6, E-value 6.9e-18 413999000604 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 413999000605 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472 413999000606 This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853 413999000607 Mg++ binding site [ion binding]; other site 413999000608 putative catalytic motif [active] 413999000609 substrate binding site [chemical binding]; other site 413999000610 10 probable transmembrane helices predicted for CBO0147 by TMHMM2.0 at aa 5-24, 47-66, 71-93, 103-122,129-151, 161-183, 190-212, 240-262, 293-315 and 320-342 413999000611 Pfam match to entry PF00953 Glycos_transf_4,Glycosyl transferase, score 155.9, E-value 7.4e-44 413999000612 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 413999000613 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 413999000614 active site 413999000615 homodimer interface [polypeptide binding]; other site 413999000616 Pfam match to entry PF02350 Epimerase_2,UDP-N-acetylglucosamine 2-epimerase, score 561.1, E-value 7.6e-166 413999000617 4 probable transmembrane helices predicted for CBO0149 by TMHMM2.0 at aa 12-31, 35-54, 67-89 and 99-118 413999000618 F0F1 ATP synthase subunit A; Validated; Region: PRK05815 413999000619 6 probable transmembrane helices predicted for CBO0150 by TMHMM2.0 at aa 17-39, 77-99, 106-125, 140-162,169-191 and 206-223 413999000620 Pfam match to entry PF00119 ATP-synt_A, ATP synthase A chain, score 75.1, E-value 1.5e-19 413999000621 PS00449 ATP synthase a subunit signature. 413999000622 F0F1 ATP synthase subunit C; Provisional; Region: PRK13469 413999000623 2 probable transmembrane helices predicted for CBO0151 by TMHMM2.0 at aa 5-27 and 55-77 413999000624 Pfam match to entry PF00137 ATP-synt_C, ATP synthase subunit C, score 102.5, E-value 8.6e-28 413999000625 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999000626 PS00605 ATP synthase c subunit signature. 413999000627 F0F1 ATP synthase subunit B; Provisional; Region: PRK13461 413999000628 F0F1 ATP synthase subunit B; Validated; Region: PRK05759 413999000629 1 probable transmembrane helix predicted for CBO0152 by TMHMM2.0 at aa 5-27 413999000630 Pfam match to entry PF00430 ATP-synt_B, ATP synthase B/B' CF(0), score 76.6, E-value 5.3e-20 413999000631 F0F1 ATP synthase subunit delta; Validated; Region: PRK05758 413999000632 ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213 413999000633 Pfam match to entry PF00213 OSCP, ATP synthase delta (OSCP) subunit, score 149.0, E-value 8.6e-42 413999000634 PS00389 ATP synthase delta (OSCP) subunit signature. 413999000635 F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281 413999000636 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 413999000637 F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132 413999000638 beta subunit interaction interface [polypeptide binding]; other site 413999000639 Walker A motif; other site 413999000640 ATP binding site [chemical binding]; other site 413999000641 Walker B motif; other site 413999000642 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 413999000643 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain, score 82.9, E-value 6.9e-22 413999000644 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000645 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain,score 368.5, E-value 7.5e-108 413999000646 PS00152 ATP synthase alpha and beta subunits signature. 413999000647 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain, score 123.1,E-value 5.3e-34 413999000648 mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151 413999000649 core domain interface [polypeptide binding]; other site 413999000650 delta subunit interface [polypeptide binding]; other site 413999000651 epsilon subunit interface [polypeptide binding]; other site 413999000652 Pfam match to entry PF00231 ATP-synt, ATP synthase,score 292.0, E-value 7.9e-85 413999000653 PS00153 ATP synthase gamma subunit signature. 413999000654 F0F1 ATP synthase subunit beta; Validated; Region: PRK09280 413999000655 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 413999000656 F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133 413999000657 alpha subunit interaction interface [polypeptide binding]; other site 413999000658 Walker A motif; other site 413999000659 ATP binding site [chemical binding]; other site 413999000660 Walker B motif; other site 413999000661 inhibitor binding site; inhibition site 413999000662 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 413999000663 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain, score 91.3, E-value 2.1e-24 413999000664 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000665 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain,score 301.2, E-value 1.3e-87 413999000666 PS00152 ATP synthase alpha and beta subunits signature. 413999000667 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain, score 169.6,E-value 5.6e-48 413999000668 F0F1 ATP synthase subunit epsilon; Provisional; Region: atpC; PRK13450 413999000669 mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152 413999000670 gamma subunit interface [polypeptide binding]; other site 413999000671 epsilon subunit interface [polypeptide binding]; other site 413999000672 LBP interface [polypeptide binding]; other site 413999000673 Pfam match to entry PF02823 ATP-synt_DE_N, ATP synthase, Delta/Epsilon chain, beta-sandwich domain, score 44.8, E-value 2.1e-10 413999000674 Protein of unknown function (DUF1779); Region: DUF1779; pfam08680 413999000675 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 413999000676 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 413999000677 hinge; other site 413999000678 active site 413999000679 Pfam match to entry PF00275 EPSP_synthase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase),score 473.9, E-value 1.3e-139 413999000680 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000681 stage II sporulation protein D; Region: spore_II_D; TIGR02870 413999000682 Stage II sporulation protein; Region: SpoIID; pfam08486 413999000683 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000684 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 413999000685 Peptidase family M23; Region: Peptidase_M23; pfam01551 413999000686 Pfam match to entry PF01551 Peptidase_M37,Peptidase M23/M37, score 54.6, E-value 2.2e-13 413999000687 Stage III sporulation protein D; Region: SpoIIID; pfam12116 413999000688 PS00894 Bacterial regulatory proteins, deoR family signature. 413999000689 Predicted helix-turn-helix motif with score 1446.000, SD 4.11 at aa 21-42, sequence ATIRKTAKVFGVSKSTIHKDMT 413999000690 rod shape-determining protein Mbl; Provisional; Region: PRK13928 413999000691 MreB and similar proteins; Region: MreB_like; cd10225 413999000692 nucleotide binding site [chemical binding]; other site 413999000693 Mg binding site [ion binding]; other site 413999000694 putative protofilament interaction site [polypeptide binding]; other site 413999000695 RodZ interaction site [polypeptide binding]; other site 413999000696 Protein of unknown function (DUF1256); Region: DUF1256; pfam06866 413999000697 tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696 413999000698 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_II; cd01993 413999000699 Ligand Binding Site [chemical binding]; other site 413999000700 Pfam match to entry PF01171 ATP_bind3, PP-loop family, score 62.7, E-value 8.5e-16 413999000701 S-adenosylmethionine synthetase; Validated; Region: PRK05250 413999000702 S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438 413999000703 S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772 413999000704 S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773 413999000705 Pfam match to entry PF00438 S-AdoMet_synt,S-adenosylmethionine synthetase, N-terminal domain, score 202.7, E-value 6e-58 413999000706 Pfam match to entry PF02772 S-AdoMet_syntD2,S-adenosylmethionine synthetase, central domain, score 286.4, E-value 3.9e-83 413999000707 PS00376 S-adenosylmethionine synthetase signature 1. 413999000708 Pfam match to entry PF02773 S-AdoMet_syntD3,S-adenosylmethionine synthetase, C-terminal domain, score 291.3, E-value 1.2e-84 413999000709 PS00377 S-adenosylmethionine synthetase signature 2. 413999000710 helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448 413999000711 AAA domain; Region: AAA_30; pfam13604 413999000712 Family description; Region: UvrD_C_2; pfam13538 413999000713 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 6.5, E-value 0.49 413999000714 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 14.8, E-value 0.0019 413999000715 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 2.0, E-value 10 413999000716 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000717 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098 413999000718 Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040 413999000719 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999000720 active site 413999000721 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 31.1, E-value 7.4e-09 413999000722 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 413999000723 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 413999000724 30S subunit binding site; other site 413999000725 Pfam match to entry PF02482 Ribosomal_S30AE, Sigma 54 modulation protein / S30EA ribosomal protein, score 97.7, E-value 2.4e-26 413999000726 preprotein translocase subunit SecA; Reviewed; Region: PRK12904 413999000727 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 413999000728 ATP binding site [chemical binding]; other site 413999000729 putative Mg++ binding site [ion binding]; other site 413999000730 SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958 413999000731 SEC-C motif; Region: SEC-C; pfam02810 413999000732 Pfam match to entry PF01043 SecA_protein, SecA protein, amino terminal region, score 921.7, E-value 2.1e-274 413999000733 PS01312 Protein secA signatures. 413999000734 Pfam match to entry PF02810 SEC-C, SEC-C motif,score 41.5, E-value 2e-09 413999000735 peptide chain release factor 2; Provisional; Region: PRK05589 413999000736 PCRF domain; Region: PCRF; pfam03462 413999000737 RF-1 domain; Region: RF-1; pfam00472 413999000738 Pfam match to entry PF03462 PCRF, PCRF domain,score 171.7, E-value 1.3e-48 413999000739 Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain, score 227.1, E-value 2.6e-65 413999000740 PS00745 Prokaryotic-type class I peptide chain release factors signature. 413999000741 Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876 413999000742 M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877 413999000743 Peptidase family M28; Region: Peptidase_M28; pfam04389 413999000744 metal binding site [ion binding]; metal-binding site 413999000745 2 probable transmembrane helices predicted for CBO0176 by TMHMM2.0 at aa 7-26 and 414-436 413999000746 Pfam match to entry PF04389 Peptidase_M28,Peptidase M28, score 144.9, E-value 1.5e-40 413999000747 Transcriptional accessory protein [Transcription]; Region: Tex; COG2183 413999000748 Tex-like protein N-terminal domain; Region: Tex_N; pfam09371 413999000749 Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732 413999000750 S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685 413999000751 RNA binding site [nucleotide binding]; other site 413999000752 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 102.0, E-value 1.2e-27 413999000753 Predicted membrane protein [Function unknown]; Region: COG3601 413999000754 Protein of unknown function (DUF3816); Region: DUF3816; pfam12822 413999000755 5 probable transmembrane helices predicted for CBO0178 by TMHMM2.0 at aa 12-31, 41-63, 76-98, 108-130 and 163-185 413999000756 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257 413999000757 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family, score 37.0, E-value 6.3e-11 413999000758 Deinococcus radiodurans DR1119 and related proteins, metallophosphatase domain; Region: MPP_DR1119; cd07393 413999000759 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 413999000760 putative active site [active] 413999000761 putative metal binding site [ion binding]; other site 413999000762 Pfam match to entry PF00149 Metallophos,Calcineurin-like phosphoesterase, score 60.6, E-value 3.5e-15 413999000763 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999000764 dimerization interface [polypeptide binding]; other site 413999000765 putative DNA binding site [nucleotide binding]; other site 413999000766 putative Zn2+ binding site [ion binding]; other site 413999000767 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family, score 43.7, E-value 4.4e-10 413999000768 Predicted helix-turn-helix motif with score 1129.000, SD 3.03 at aa 36-57, sequence CNVSHMQNCLDMPQSTISQHLQ 413999000769 CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385 413999000770 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999000771 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999000772 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 413999000773 Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524 413999000774 active site residue [active] 413999000775 SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436 413999000776 CPxP motif; other site 413999000777 DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686 413999000778 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 274.1, E-value 1.9e-79 413999000779 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain,score 41.2, E-value 2.4e-09 413999000780 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 46.6, E-value 5.9e-11 413999000781 Pfam match to entry PF01206 UPF0033,Uncharacterized protein family UPF0033, score 48.2,E-value 1.9e-11 413999000782 PS01148 Uncharacterized protein family UPF0033 signature. 413999000783 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655 413999000784 Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986 413999000785 Pfam match to entry PF04460 DUF517, Protein of unknown function (DUF517), score 221.4, E-value 1.4e-63 413999000786 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 413999000787 synthetase active site [active] 413999000788 NTP binding site [chemical binding]; other site 413999000789 metal binding site [ion binding]; metal-binding site 413999000790 Pfam match to entry PF04607 RelA_SpoT, Region found in RelA / SpoT proteins, score 186.6, E-value 4.2e-53 413999000791 leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390 413999000792 catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812 413999000793 HIGH motif; other site 413999000794 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 413999000795 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 413999000796 active site 413999000797 KMSKS motif; other site 413999000798 Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958 413999000799 tRNA binding surface [nucleotide binding]; other site 413999000800 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V), score 457.3, E-value 1.3e-134 413999000801 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 413999000802 active site residue [active] 413999000803 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 55.9, E-value 9e-14 413999000804 5 probable transmembrane helices predicted for CBO0188 by TMHMM2.0 at aa 9-31, 41-63, 70-92, 107-129 and 142-164 413999000805 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 413999000806 HSP70 interaction site [polypeptide binding]; other site 413999000807 Pfam match to entry PF00226 DnaJ, DnaJ domain,score 85.4, E-value 1.2e-22 413999000808 Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890 413999000809 putative active site [active] 413999000810 putative triphosphate binding site [ion binding]; other site 413999000811 dimer interface [polypeptide binding]; other site 413999000812 Pfam match to entry PF01928 CYTH, CYTH domain,score 103.8, E-value 3.6e-28 413999000813 37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245 413999000814 Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947 413999000815 fructose-bisphosphate aldolase; Provisional; Region: PRK09197 413999000816 intersubunit interface [polypeptide binding]; other site 413999000817 active site 413999000818 zinc binding site [ion binding]; other site 413999000819 Na+ binding site [ion binding]; other site 413999000820 Pfam match to entry PF01116 F_bP_aldolase,Fructose-bisphosphate aldolase class-II, score 406.8,E-value 2.1e-119 413999000821 Domain of unknown function (DUF4363); Region: DUF4363; pfam14276 413999000822 Predicted membrane protein [Function unknown]; Region: COG2323 413999000823 Pfam match to entry PF04239 DUF421, Protein of unknown function (DUF421), score 183.3, E-value 4.1e-52 413999000824 2 probable transmembrane helices predicted for CBO0195 by TMHMM2.0 at aa 3-22 and 54-76 413999000825 Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572 413999000826 Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028 413999000827 active site 413999000828 Pfam match to entry PF00485 PRK,Phosphoribulokinase / Uridine kinase, score 12.8,E-value 2e-08 413999000829 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000830 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066 413999000831 CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473 413999000832 Pfam match to entry PF01066 CDP-OH_P_transf,CDP-alcohol phosphatidyltransferase, score 61.0, E-value 2.6e-15 413999000833 4 probable transmembrane helices predicted for CBO0198 by TMHMM2.0 at aa 7-29, 85-107, 120-142 and 147-166 413999000834 PS00379 CDP-alcohol phosphatidyltransferases signature. 413999000835 FOG: CBS domain [General function prediction only]; Region: COG0517 413999000836 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622 413999000837 Pfam match to entry PF00571 CBS, CBS domain, score 68.9, E-value 1.1e-17 413999000838 Pfam match to entry PF00571 CBS, CBS domain, score 62.9, E-value 7.3e-16 413999000839 putative lipid kinase; Reviewed; Region: PRK13059 413999000840 Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781 413999000841 Pfam match to entry PF00781 DAGKc, Diacylglycerol kinase catalytic domain (presumed), score 36.1, E-value 7.1e-10 413999000842 7 probable transmembrane helices predicted for CBO0201 by TMHMM2.0 at aa 4-21, 34-56, 66-88, 95-117,132-154, 167-186 and 190-209 413999000843 Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497 413999000844 hypothetical protein; Provisional; Region: PRK00955 413999000845 Domain of unknown function (DUF3362); Region: DUF3362; pfam11842 413999000846 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 17.4, E-value 0.015 413999000847 PRC-barrel domain; Region: PRC; pfam05239 413999000848 Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239 413999000849 MgtE intracellular N domain; Region: MgtE_N; smart00924 413999000850 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE. MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606 413999000851 Pfam match to entry PF05239 PRC, PRC-barrel domain,score 25.7, E-value 0.00011 413999000852 Pfam match to entry PF03448 MgtE_N, MgtE intracellular domain, score 124.2, E-value 2.5e-34 413999000853 Pfam match to entry PF00571 CBS, CBS domain, score 25.5, E-value 0.00013 413999000854 Pfam match to entry PF00571 CBS, CBS domain, score 43.6, E-value 4.6e-10 413999000855 spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869 413999000856 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 413999000857 Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486 413999000858 1 probable transmembrane helix predicted for CBO0204 by TMHMM2.0 at aa 12-34 413999000859 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain, score 76.4, E-value 6.1e-20 413999000860 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 413999000861 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 413999000862 dimer interface [polypeptide binding]; other site 413999000863 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999000864 catalytic residue [active] 413999000865 Pfam match to entry PF00291 PALP,Pyridoxal-phosphate dependent enzyme, score 426.6, E-value 2.3e-125 413999000866 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 413999000867 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 413999000868 Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045 413999000869 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 413999000870 trimer interface [polypeptide binding]; other site 413999000871 active site 413999000872 substrate binding site [chemical binding]; other site 413999000873 CoA binding site [chemical binding]; other site 413999000874 1 probable transmembrane helix predicted for CBO0206 by TMHMM2.0 at aa 21-43 413999000875 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 8.7,E-value 8.6 413999000876 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 16.5,E-value 0.066 413999000877 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.7,E-value 3.8 413999000878 PS00101 Hexapeptide-repeat containing-transferases signature. 413999000879 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 13.7,E-value 0.48 413999000880 Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600 413999000881 Domain of unknown function (DUF1730); Region: DUF1730; pfam08331 413999000882 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 9.8, E-value 0.0074 413999000883 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999000884 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 413999000885 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 413999000886 putative acyl-acceptor binding pocket; other site 413999000887 Pfam match to entry PF01553 Acyltransferase,Acyltransferase, score 96.7, E-value 4.7e-26 413999000888 Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177 413999000889 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 413999000890 minor groove reading motif; other site 413999000891 helix-hairpin-helix signature motif; other site 413999000892 substrate binding pocket [chemical binding]; other site 413999000893 active site 413999000894 iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525 413999000895 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein, score 67.1,E-value 4e-17 413999000896 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 27.1, E-value 4.3e-05 413999000897 PS01155 Endonuclease III family signature. 413999000898 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 183-204, sequence GRRCCVARKPKCEECTIKKYCK 413999000899 PS00764 Endonuclease III iron-sulfur binding region signature. 413999000900 Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281 413999000901 Malic enzyme, N-terminal domain; Region: malic; pfam00390 413999000902 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 413999000903 putative NAD(P) binding site [chemical binding]; other site 413999000904 Pfam match to entry PF00390 malic, Malic enzyme,N-terminal domain, score 267.2, E-value 2.2e-77 413999000905 Pfam match to entry PF03949 malic_N, Malic enzyme,NAD binding domain, score 396.2, E-value 3.3e-116 413999000906 PS00217 Sugar transport proteins signature 2. 413999000907 competence damage-inducible protein A; Provisional; Region: PRK00549 413999000908 Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885 413999000909 putative MPT binding site; other site 413999000910 Competence-damaged protein; Region: CinA; pfam02464 413999000911 Pfam match to entry PF02464 CinA,Competence-damaged protein, score 217.2, E-value 2.5e-62 413999000912 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000913 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain, score 49.1, E-value 1e-11 413999000914 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 413999000915 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 413999000916 1 probable transmembrane helix predicted for CBO0212 by TMHMM2.0 at aa 17-36 413999000917 Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363 413999000918 M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657 413999000919 putative oligomer interface [polypeptide binding]; other site 413999000920 putative active site [active] 413999000921 metal binding site [ion binding]; metal-binding site 413999000922 Pfam match to entry PF05343 Peptidase_M42, M42 glutamyl aminopeptidase, score 379.5, E-value 3.6e-111 413999000923 Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229 413999000924 VanW like protein; Region: VanW; pfam04294 413999000925 PS00063 Aldo/keto reductase active site signature. 413999000926 1 probable transmembrane helix predicted for CBO0214 by TMHMM2.0 at aa 20-39 413999000927 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000928 Pfam match to entry PF04294 VanW, VanW like protein, score 222.9, E-value 4.8e-64 413999000929 Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229 413999000930 VanW like protein; Region: VanW; pfam04294 413999000931 G5 domain; Region: G5; pfam07501 413999000932 1 probable transmembrane helix predicted for CBO0215 by TMHMM2.0 at aa 9-28 413999000933 Pfam match to entry PF04294 VanW, VanW like protein, score 226.0, E-value 5.7e-65 413999000934 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000935 DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533 413999000936 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999000937 FeS/SAM binding site; other site 413999000938 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 28.8, E-value 1.4e-05 413999000939 Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219 413999000940 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase, score 136.3, E-value 5.8e-38 413999000941 EDD domain protein, DegV family; Region: DegV; TIGR00762 413999000942 Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645 413999000943 Pfam match to entry PF02645 DUF194, Uncharacterized protein, DegV family COG1307, score 260.5, E-value 2.3e-75 413999000944 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744 413999000945 Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354 413999000946 ligand binding site [chemical binding]; other site 413999000947 Pfam match to entry PF02608 Bmp, Basic membrane protein, score 270.6, E-value 2.1e-78 413999000948 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999000949 ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845 413999000950 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 413999000951 Walker A/P-loop; other site 413999000952 ATP binding site [chemical binding]; other site 413999000953 Q-loop/lid; other site 413999000954 ABC transporter signature motif; other site 413999000955 Walker B; other site 413999000956 D-loop; other site 413999000957 H-loop/switch region; other site 413999000958 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 413999000959 Pfam match to entry PF00005 ABC_tran, ABC transporter score 167.4, E-value 2.5e-47 413999000960 PS00017 ATP/GTP-binding site motif A (P-loop). 413999000961 PS00211 ABC transporters family signature. 413999000962 Pfam match to entry PF00005 ABC_tran, ABC transporter score 75.6, E-value 1.1e-19 413999000963 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 413999000964 Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580 413999000965 TM-ABC transporter signature motif; other site 413999000966 8 probable transmembrane helices predicted for CBO0221 by TMHMM2.0 at aa 20-42, 76-93, 100-122, 126-145,158-177, 207-226, 256-278 and 334-356 413999000967 Pfam match to entry PF02653 BPD_transp_2,Branched-chain amino acid transport system / permease component, score 177.3, E-value 2.7e-50 413999000968 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 413999000969 Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580 413999000970 TM-ABC transporter signature motif; other site 413999000971 9 probable transmembrane helices predicted for CBO0222 by TMHMM2.0 at aa 4-26, 33-52, 62-84, 91-113,142-164, 196-218, 223-240, 247-269 and 273-290 413999000972 Pfam match to entry PF02653 BPD_transp_2,Branched-chain amino acid transport system / permease component, score 176.5, E-value 4.6e-50 413999000973 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 413999000974 Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944 413999000975 NodB motif; other site 413999000976 active site 413999000977 catalytic site [active] 413999000978 Zn binding site [ion binding]; other site 413999000979 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 140.8, E-value 2.6e-39 413999000980 RNA polymerase factor sigma-54; Reviewed; Region: PRK05932 413999000981 Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309 413999000982 Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963 413999000983 Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552 413999000984 Pfam match to entry PF00309 sigma54_AID, Sigma-54 factor, Activator interacting domain (AID), score 65.6,E-value 1.1e-16 413999000985 Pfam match to entry PF04963 sigma54_CBD, Sigma-54 factor, core binding domain, score 105.7, E-value 9.5e-29 413999000986 Pfam match to entry PF04552 sigma54_DBD, Sigma-54,DNA binding domain, score 249.7, E-value 4.1e-72 413999000987 PS00717 Sigma-54 factors family signature 1. 413999000988 Predicted helix-turn-helix motif with score 2571.000, SD 7.94 at aa 344-365, sequence MTLKEIADSLGMHESTISRAIR 413999000989 PS00718 Sigma-54 factors family signature 2. 413999000990 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 413999000991 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 413999000992 Pfam match to entry PF04198 Sugar-bind, sugar-binding domain, score 274.6, E-value 1.3e-79 413999000993 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057 413999000994 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 413999000995 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 413999000996 Pfam match to entry PF00044 gpdh, Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain, score 317.3, E-value 1.9e-92 413999000997 PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 413999000998 Pfam match to entry PF02800 gpdh_C, Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, score 395.2,E-value 6.6e-116 413999000999 Phosphoglycerate kinase; Region: PGK; pfam00162 413999001000 Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318 413999001001 substrate binding site [chemical binding]; other site 413999001002 hinge regions; other site 413999001003 ADP binding site [chemical binding]; other site 413999001004 catalytic site [active] 413999001005 Pfam match to entry PF00162 PGK, Phosphoglycerate kinase, score 784.8, E-value 3.6e-233 413999001006 PS00111 Phosphoglycerate kinase signature. 413999001007 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 413999001008 triosephosphate isomerase; Provisional; Region: PRK14567 413999001009 Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311 413999001010 substrate binding site [chemical binding]; other site 413999001011 dimer interface [polypeptide binding]; other site 413999001012 catalytic triad [active] 413999001013 Pfam match to entry PF00121 TIM, Triosephosphate isomerase, score 445.6, E-value 4.6e-131 413999001014 PS00171 Triosephosphate isomerase active site. 413999001015 Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696 413999001016 phosphoglyceromutase; Provisional; Region: PRK05434 413999001017 Pfam match to entry PF01676 Metalloenzyme,Metalloenzyme superfamily, score 169.4, E-value 6.1e-48 413999001018 enolase; Provisional; Region: eno; PRK00077 413999001019 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313 413999001020 dimer interface [polypeptide binding]; other site 413999001021 metal binding site [ion binding]; metal-binding site 413999001022 substrate binding pocket [chemical binding]; other site 413999001023 Pfam match to entry PF03952 enolase_N, Enolase,N-terminal domain, score 236.6, E-value 3.7e-68 413999001024 Pfam match to entry PF00113 enolase, Enolase,C-terminal TIM barrel domain, score 604.6, E-value 6.1e-179 413999001025 PS00164 Enolase signature. 413999001026 Preprotein translocase SecG subunit; Region: SecG; pfam03840 413999001027 Pfam match to entry PF03840 SecG, Preprotein translocase SecG subunit, score 77.9, E-value 2.2e-20 413999001028 2 probable transmembrane helices predicted for CBO0231 by TMHMM2.0 at aa 4-21 and 53-75 413999001029 ribonuclease R; Region: RNase_R; TIGR02063 413999001030 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 413999001031 S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927 413999001032 RNB domain; Region: RNB; pfam00773 413999001033 S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471 413999001034 RNA binding site [nucleotide binding]; other site 413999001035 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain, score 11.8, E-value 0.0081 413999001036 Pfam match to entry PF00773 RNB, RNB-like protein,score 490.3, E-value 1.5e-144 413999001037 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 63.1, E-value 6.3e-16 413999001038 stationary phase survival protein SurE; Provisional; Region: PRK13933 413999001039 Pfam match to entry PF01975 SurE, Survival protein SurE, score 251.7, E-value 1.1e-72 413999001040 Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294 413999001041 SmpB-tmRNA interface; other site 413999001042 Pfam match to entry PF01668 SmpB, SmpB protein,score 165.2, E-value 1.2e-46 413999001043 PS01317 Protein smpB signature. 413999001044 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 413999001045 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 413999001046 Pfam match to entry PF00375 SDF,Sodium:dicarboxylate symporter family, score -112.2,E-value 9.7e-06 413999001047 10 probable transmembrane helices predicted for CBO0235 by TMHMM2.0 at aa 13-35, 39-58, 71-93, 122-144,164-186, 201-223, 236-255, 270-292, 299-321 and 336-358 413999001048 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 413999001049 FAD binding domain; Region: FAD_binding_4; pfam01565 413999001050 Berberine and berberine like; Region: BBE; pfam08031 413999001051 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain, score 148.5, E-value 1.2e-41 413999001052 Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737 413999001053 Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076 413999001054 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999001055 catalytic residue [active] 413999001056 Pfam match to entry PF00282 pyridoxal_deC,Pyridoxal-dependent decarboxylase domain, score 60.7, E-value 6.4e-19 413999001057 flagellin; Provisional; Region: PRK12804 413999001058 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999001059 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 413999001060 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 241.0, E-value 1.8e-69 413999001061 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus, score 95.3, E-value 1.3e-25 413999001062 PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398 413999001063 active site 413999001064 Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662 413999001065 2 probable transmembrane helices predicted for CBO0245 by TMHMM2.0 at aa 4-22 and 194-216 413999001066 Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281 413999001067 Malic enzyme, N-terminal domain; Region: malic; pfam00390 413999001068 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 413999001069 putative NAD(P) binding site [chemical binding]; other site 413999001070 Pfam match to entry PF00390 malic, Malic enzyme,N-terminal domain, score 296.5, E-value 3.3e-86 413999001071 PS00331 Malic enzymes signature. 413999001072 Pfam match to entry PF03949 malic_N, Malic enzyme,NAD binding domain, score 382.0, E-value 6.4e-112 413999001073 2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274 413999001074 Pfam match to entry PF03812 KdgT,2-keto-3-deoxygluconate permease, score 211.8, E-value 1.1e-60 413999001075 8 probable transmembrane helices predicted for CBO0247 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 163-185,192-210, 220-242, 249-271 and 284-306 413999001076 Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290 413999001077 PAS domain; Region: PAS; smart00091 413999001078 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001079 ATP binding site [chemical binding]; other site 413999001080 Mg2+ binding site [ion binding]; other site 413999001081 G-X-G motif; other site 413999001082 2 probable transmembrane helices predicted for CBO0248 by TMHMM2.0 at aa 11-33 and 171-193 413999001083 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001084 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 77.2,E-value 3.5e-20 413999001085 Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565 413999001086 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001087 active site 413999001088 phosphorylation site [posttranslational modification] 413999001089 intermolecular recognition site; other site 413999001090 dimerization interface [polypeptide binding]; other site 413999001091 HTH domain; Region: HTH_11; cl17392 413999001092 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 104.5, E-value 2.1e-28 413999001093 Predicted helix-turn-helix motif with score 1797.000, SD 5.31 at aa 176-197, sequence FTAEYLAEKLGIARVTVRRYLE 413999001094 lysine transporter; Provisional; Region: PRK10836 413999001095 12 probable transmembrane helices predicted for CBO0250 by TMHMM2.0 at aa 20-42, 52-74, 94-116, 131-148,161-183, 198-220, 245-267, 294-316, 336-358, 362-384,408-430 and 440-459 413999001096 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score 559.6, E-value 2.2e-165 413999001097 PS00435 Peroxidases proximal heme-ligand signature. 413999001098 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999001099 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 55.8, E-value 9.9e-14 413999001100 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999001101 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 19.4, E-value 0.004 413999001102 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 413999001103 active site 413999001104 catalytic motif [active] 413999001105 Zn binding site [ion binding]; other site 413999001106 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region, score -0.4, E-value 0.0034 413999001107 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 413999001108 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999001109 Coenzyme A binding pocket [chemical binding]; other site 413999001110 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 37.8, E-value 2.7e-08 413999001111 RibD C-terminal domain; Region: RibD_C; cl17279 413999001112 Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262 413999001113 Pfam match to entry PF01872 RibD_C, RibD C-terminal domain, score 46.6, E-value 5.8e-11 413999001114 DNA polymerase III subunit epsilon; Validated; Region: PRK06195 413999001115 an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130 413999001116 active site 413999001117 catalytic site [active] 413999001118 substrate binding site [chemical binding]; other site 413999001119 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 413999001120 Dimer interface [polypeptide binding]; other site 413999001121 Pfam match to entry PF00929 Exonuclease,Exonuclease, score 67.3, E-value 3.5e-17 413999001122 Pfam match to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) domain, score 20.4, E-value 1.1e-05 413999001123 Isochorismatase family; Region: Isochorismatase; pfam00857 413999001124 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 413999001125 catalytic triad [active] 413999001126 conserved cis-peptide bond; other site 413999001127 Pfam match to entry PF00857 Isochorismatase,Isochorismatase, score 33.1, E-value 3e-10 413999001128 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 413999001129 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 413999001130 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 413999001131 Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain,score 128.1, E-value 1.7e-35 413999001132 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain, score 281.7, E-value 9.7e-82 413999001133 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001134 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319 413999001135 CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092 413999001136 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 413999001137 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 413999001138 catalytic loop [active] 413999001139 iron binding site [ion binding]; other site 413999001140 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 413999001141 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain, score 9.6, E-value 0.033 413999001142 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 413999001143 Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding domain, score 120.1, E-value 4.3e-33 413999001144 Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785 413999001145 Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683 413999001146 Pfam match to entry PF02683 DsbD, Cytochrome C biogenesis protein transmembrane region, score 200.0,E-value 3.7e-57 413999001147 6 probable transmembrane helices predicted for CBO0262 by TMHMM2.0 at aa 10-32, 45-67, 82-104, 125-147,162-181 and 202-224 413999001148 PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 413999001149 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 413999001150 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 413999001151 catalytic residues [active] 413999001152 1 probable transmembrane helix predicted for CBO0263 by TMHMM2.0 at aa 7-29 413999001153 Pfam match to entry PF00085 thiored, Thioredoxin,score 17.6, E-value 0.00025 413999001154 phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154 413999001155 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001156 active site 413999001157 phosphorylation site [posttranslational modification] 413999001158 intermolecular recognition site; other site 413999001159 dimerization interface [polypeptide binding]; other site 413999001160 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999001161 DNA binding site [nucleotide binding] 413999001162 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 131.9, E-value 1.2e-36 413999001163 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 77.3, E-value 3.4e-20 413999001164 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001165 HAMP domain; Region: HAMP; pfam00672 413999001166 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999001167 dimer interface [polypeptide binding]; other site 413999001168 phosphorylation site [posttranslational modification] 413999001169 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001170 ATP binding site [chemical binding]; other site 413999001171 Mg2+ binding site [ion binding]; other site 413999001172 G-X-G motif; other site 413999001173 2 probable transmembrane helices predicted for CBO0265 by TMHMM2.0 at aa 15-37 and 175-197 413999001174 Pfam match to entry PF00672 HAMP, HAMP domain,score 42.2, E-value 1.2e-09 413999001175 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 51.9, E-value 1.5e-12 413999001176 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 147.1, E-value 3.3e-41 413999001177 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 413999001178 FAD binding domain; Region: FAD_binding_4; pfam01565 413999001179 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain, score 152.8, E-value 6e-43 413999001180 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486 413999001181 Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298 413999001182 NAD binding site [chemical binding]; other site 413999001183 sugar binding site [chemical binding]; other site 413999001184 divalent metal binding site [ion binding]; other site 413999001185 putative tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999001186 dimer interface [polypeptide binding]; other site 413999001187 Pfam match to entry PF02056 Glyco_hydro_4, Family 4 glycosyl hydrolase, score 358.7, E-value 6.6e-105 413999001188 bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110 413999001189 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999001190 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999001191 active site turn [active] 413999001192 phosphorylation site [posttranslational modification] 413999001193 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 195.9, E-value 6.5e-56 413999001194 10 probable transmembrane helices predicted for CBO0268 by TMHMM2.0 at aa 17-39, 54-85, 92-114, 134-151,172-194, 198-220, 271-293, 308-330, 337-359 and 381-403 413999001195 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 56.9, E-value 4.5e-14 413999001196 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999001197 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999001198 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999001199 putative active site [active] 413999001200 Pfam match to entry PF01380 SIS, SIS domain, score 6.2, E-value 0.012 413999001201 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family, score 37.0, E-value 4.4e-08 413999001202 Predicted helix-turn-helix motif with score 1429.000, SD 4.05 at aa 34-55, sequence MSIHEFAQITYVSTATVLRLCK 413999001203 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999001204 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999001205 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999001206 putative active site [active] 413999001207 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family, score 28.5, E-value 2.2e-06 413999001208 Predicted helix-turn-helix motif with score 1349.000, SD 3.78 at aa 34-55, sequence MSIQELSEKVFFSTATILRLCK 413999001209 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 413999001210 HPr interaction site; other site 413999001211 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999001212 active site 413999001213 phosphorylation site [posttranslational modification] 413999001214 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 169.1, E-value 7.9e-48 413999001215 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999001216 1 probable transmembrane helix predicted for CBO0272 by TMHMM2.0 at aa 13-32 413999001217 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999001218 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001219 active site 413999001220 phosphorylation site [posttranslational modification] 413999001221 intermolecular recognition site; other site 413999001222 dimerization interface [polypeptide binding]; other site 413999001223 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999001224 DNA binding site [nucleotide binding] 413999001225 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 77.2, E-value 3.6e-20 413999001226 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 84.0, E-value 3.2e-22 413999001227 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001228 His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388 413999001229 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001230 ATP binding site [chemical binding]; other site 413999001231 Mg2+ binding site [ion binding]; other site 413999001232 G-X-G motif; other site 413999001233 2 probable transmembrane helices predicted for CBO0273 by TMHMM2.0 at aa 15-37 and 42-64 413999001234 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 13.6, E-value 0.0043 413999001235 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 119.5, E-value 6.7e-33 413999001236 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999001237 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999001238 Walker A/P-loop; other site 413999001239 ATP binding site [chemical binding]; other site 413999001240 Q-loop/lid; other site 413999001241 ABC transporter signature motif; other site 413999001242 Walker B; other site 413999001243 D-loop; other site 413999001244 H-loop/switch region; other site 413999001245 Pfam match to entry PF00005 ABC_tran, ABC transporter score 196.2, E-value 5.4e-56 413999001246 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001247 10 probable transmembrane helices predicted for CBO0275 by TMHMM2.0 at aa 21-40, 60-82, 109-131, 151-173,206-228, 232-254, 286-305, 539-561, 592-614 and 624-643 413999001248 Pfam match to entry PF02687 FtsX, Predicted permease, score 32.3, E-value 1.2e-06 413999001249 alanine racemase; Reviewed; Region: alr; PRK00053 413999001250 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430 413999001251 active site 413999001252 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999001253 dimer interface [polypeptide binding]; other site 413999001254 substrate binding site [chemical binding]; other site 413999001255 catalytic residues [active] 413999001256 Pfam match to entry PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain, score 291.9, E-value 8.3e-85 413999001257 PS00395 Alanine racemase pyridoxal-phosphate attachment site. 413999001258 PS00572 Glycosyl hydrolases family 1 active site. 413999001259 Pfam match to entry PF00842 Ala_racemase_C, Alanine racemase, C-terminal domain, score 227.4, E-value 2.3e-65 413999001260 PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005 413999001261 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999001262 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999001263 active site turn [active] 413999001264 phosphorylation site [posttranslational modification] 413999001265 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 205.0, E-value 1.2e-58 413999001266 10 probable transmembrane helices predicted for CBO0277 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 129-151,172-194, 198-220, 278-300, 320-342, 349-371 and 384-406 413999001267 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 52.9, E-value 7.6e-13 413999001268 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486 413999001269 Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298 413999001270 NAD binding site [chemical binding]; other site 413999001271 sugar binding site [chemical binding]; other site 413999001272 divalent metal binding site [ion binding]; other site 413999001273 putative tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999001274 dimer interface [polypeptide binding]; other site 413999001275 Pfam match to entry PF02056 Glyco_hydro_4, Family 4 glycosyl hydrolase, score 751.2, E-value 4.6e-223 413999001276 PS01324 Glycosyl hydrolases family 4 signature. 413999001277 PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210 413999001278 HPr interaction site; other site 413999001279 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999001280 active site 413999001281 phosphorylation site [posttranslational modification] 413999001282 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 206.5, E-value 4.2e-59 413999001283 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999001284 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999001285 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999001286 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999001287 putative active site [active] 413999001288 Pfam match to entry PF01380 SIS, SIS domain, score 17.2, E-value 0.0022 413999001289 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 413999001290 DNA-binding site [nucleotide binding]; DNA binding site 413999001291 RNA-binding motif; other site 413999001292 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain, score 137.6, E-value 2.4e-38 413999001293 PS00352 'Cold-shock' DNA-binding domain signature. 413999001294 Protein of unknown function (DUF1003); Region: DUF1003; pfam06210 413999001295 Pfam match to entry PF06210 DUF1003, Protein of unknown function (DUF1003), score 204.1, E-value 2.2e-58 413999001296 2 probable transmembrane helices predicted for CBO0283 by TMHMM2.0 at aa 65-87 and 102-124 413999001297 Predicted transcriptional regulator [Transcription]; Region: COG1959 413999001298 Transcriptional regulator; Region: Rrf2; pfam02082 413999001299 Pfam match to entry PF02082 Rrf2, Transcriptional regulator, score 16.0, E-value 9.2e-07 413999001300 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761 413999001301 DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024 413999001302 catalytic residues [active] 413999001303 Pfam match to entry PF01323 DSBA, DSBA-like thioredoxin domain, score 95.2, E-value 1.3e-25 413999001304 biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244 413999001305 NADH(P)-binding; Region: NAD_binding_10; pfam13460 413999001306 NAD binding site [chemical binding]; other site 413999001307 substrate binding site [chemical binding]; other site 413999001308 putative active site [active] 413999001309 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999001310 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999001311 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999001312 putative active site [active] 413999001313 Pfam match to entry PF01380 SIS, SIS domain, score 3.9, E-value 0.016 413999001314 bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110 413999001315 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999001316 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999001317 active site turn [active] 413999001318 phosphorylation site [posttranslational modification] 413999001319 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 255.8, E-value 6.3e-74 413999001320 10 probable transmembrane helices predicted for CBO0288 by TMHMM2.0 at aa 20-42, 67-89, 96-115, 135-157,178-200, 205-227, 289-308, 318-340, 347-369 and 391-413 413999001321 PS00079 Multicopper oxidases signature 1. 413999001322 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 60.4, E-value 4e-15 413999001323 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999001324 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486 413999001325 Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298 413999001326 NAD binding site [chemical binding]; other site 413999001327 sugar binding site [chemical binding]; other site 413999001328 divalent metal binding site [ion binding]; other site 413999001329 putative tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999001330 dimer interface [polypeptide binding]; other site 413999001331 1 probable transmembrane helix predicted for CBO0289 by TMHMM2.0 at aa 7-26 413999001332 Pfam match to entry PF02056 Glyco_hydro_4, Family 4 glycosyl hydrolase, score 633.6, E-value 1.2e-187 413999001333 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 413999001334 HPr interaction site; other site 413999001335 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999001336 active site 413999001337 phosphorylation site [posttranslational modification] 413999001338 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 153.8, E-value 3.1e-43 413999001339 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999001340 Dehydratase family; Region: ILVD_EDD; pfam00920 413999001341 Pfam match to entry PF00920 ILVD_EDD, Dehydratase, score 768.7, E-value 2.4e-228 413999001342 PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 413999001343 2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800 413999001344 KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452 413999001345 active site 413999001346 intersubunit interface [polypeptide binding]; other site 413999001347 catalytic residue [active] 413999001348 Pfam match to entry PF01081 Aldolase, KDPG and KHG aldolase, score 90.0, E-value 4.9e-24 413999001349 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 413999001350 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 413999001351 substrate binding site [chemical binding]; other site 413999001352 ATP binding site [chemical binding]; other site 413999001353 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 95.5, E-value 1.1e-25 413999001354 Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001 413999001355 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 413999001356 Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295 413999001357 active site 413999001358 Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382 413999001359 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 97.0, E-value 3.9e-26 413999001360 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999001361 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001362 active site 413999001363 phosphorylation site [posttranslational modification] 413999001364 intermolecular recognition site; other site 413999001365 dimerization interface [polypeptide binding]; other site 413999001366 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999001367 DNA binding site [nucleotide binding] 413999001368 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 104.9, E-value 1.6e-28 413999001369 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 78.5, E-value 1.4e-20 413999001370 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001371 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999001372 dimerization interface [polypeptide binding]; other site 413999001373 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999001374 dimer interface [polypeptide binding]; other site 413999001375 phosphorylation site [posttranslational modification] 413999001376 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001377 ATP binding site [chemical binding]; other site 413999001378 Mg2+ binding site [ion binding]; other site 413999001379 G-X-G motif; other site 413999001380 2 probable transmembrane helices predicted for CBO0296 by TMHMM2.0 at aa 13-35 and 173-195 413999001381 Pfam match to entry PF00672 HAMP, HAMP domain,score 60.3, E-value 4.2e-15 413999001382 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 36.3, E-value 7.6e-08 413999001383 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 84.0,E-value 3.3e-22 413999001384 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 413999001385 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 413999001386 Ligand binding site; other site 413999001387 Putative Catalytic site; other site 413999001388 DXD motif; other site 413999001389 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 131.5, E-value 1.6e-36 413999001390 2 probable transmembrane helices predicted for CBO0297 by TMHMM2.0 at aa 231-253 and 268-290 413999001391 Predicted membrane protein [Function unknown]; Region: COG2246 413999001392 GtrA-like protein; Region: GtrA; pfam04138 413999001393 Pfam match to entry PF04138 GtrA, GtrA-like protein, score 93.7, E-value 4e-25 413999001394 3 probable transmembrane helices predicted for CBO0298 by TMHMM2.0 at aa 50-72, 92-114 and 121-143 413999001395 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 413999001396 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231 413999001397 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 413999001398 Pfam match to entry PF02366 PMT,Dolichyl-phosphate-mannose-protein mannosyltransferase,score 72.9, E-value 6.9e-19 413999001399 13 probable transmembrane helices predicted for CBO0299 by TMHMM2.0 at aa 13-32, 52-74, 86-108, 112-134,141-158, 171-193, 206-228, 398-415, 428-447, 451-473,485-507, 512-534 and 555-577 413999001400 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999001401 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999001402 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 50.5, E-value 3.9e-12 413999001403 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999001404 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 413999001405 intersubunit interface [polypeptide binding]; other site 413999001406 1 probable transmembrane helix predicted for CBO0301 by TMHMM2.0 at aa 5-27 413999001407 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001408 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001409 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 51.7, E-value 1.7e-12 413999001410 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 413999001411 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999001412 ABC-ATPase subunit interface; other site 413999001413 dimer interface [polypeptide binding]; other site 413999001414 putative PBP binding regions; other site 413999001415 9 probable transmembrane helices predicted for CBO0302 by TMHMM2.0 at aa 26-48, 89-111, 123-145, 155-177,184-206, 226-248, 278-300, 315-334 and 341-363 413999001416 Pfam match to entry PF01032 FecCD, FecCD transport family, score 348.0, E-value 1.1e-101 413999001417 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 413999001418 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999001419 Walker A/P-loop; other site 413999001420 ATP binding site [chemical binding]; other site 413999001421 Q-loop/lid; other site 413999001422 ABC transporter signature motif; other site 413999001423 Walker B; other site 413999001424 D-loop; other site 413999001425 H-loop/switch region; other site 413999001426 Pfam match to entry PF00005 ABC_tran, ABC transporter score 199.1, E-value 7.1e-57 413999001427 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001428 PS00211 ABC transporters family signature. 413999001429 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999001430 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138 413999001431 12 probable transmembrane helices predicted for CBO0304 by TMHMM2.0 at aa 12-34, 49-71, 92-114, 134-156,163-185, 189-211, 232-249, 254-276, 313-335, 355-377,384-406 and 411-430 413999001432 Pfam match to entry PF01554 MatE, MatE, score 133.2, E-value 5e-37 413999001433 Pfam match to entry PF01554 MatE, MatE, score 95.8,E-value 8.9e-26 413999001434 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 413999001435 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999001436 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 45.8, E-value 1e-10 413999001437 PS00041 Bacterial regulatory proteins, araC family signature. 413999001438 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 13.7, E-value 0.074 413999001439 Predicted helix-turn-helix motif with score 1093.000, SD 2.91 at aa 236-257, sequence PTIEEMKNIAEMSESKLRRCFK 413999001440 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999001441 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 413999001442 intersubunit interface [polypeptide binding]; other site 413999001443 1 probable transmembrane helix predicted for CBO0306 by TMHMM2.0 at aa 7-24 413999001444 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001445 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 110.0, E-value 4.9e-30 413999001446 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 413999001447 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 36.9, E-value 4.9e-08 413999001448 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 8.4, E-value 0.31 413999001449 Predicted helix-turn-helix motif with score 1115.000, SD 2.98 at aa 235-256, sequence PDTIELCRIAGMSESKLRQSFK 413999001450 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999001451 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 413999001452 intersubunit interface [polypeptide binding]; other site 413999001453 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001454 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 74.8, E-value 1.9e-19 413999001455 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 413999001456 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999001457 ABC-ATPase subunit interface; other site 413999001458 dimer interface [polypeptide binding]; other site 413999001459 putative PBP binding regions; other site 413999001460 9 probable transmembrane helices predicted for CBO0311 by TMHMM2.0 at aa 13-35, 67-89, 101-123, 128-150,157-179, 208-230, 251-273, 288-310 and 317-336 413999001461 Pfam match to entry PF01032 FecCD, FecCD transport family, score 372.8, E-value 3.7e-109 413999001462 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 413999001463 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999001464 ABC-ATPase subunit interface; other site 413999001465 dimer interface [polypeptide binding]; other site 413999001466 putative PBP binding regions; other site 413999001467 9 probable transmembrane helices predicted for CBO0312 by TMHMM2.0 at aa 7-29, 65-87, 94-113, 123-145,154-176, 199-218, 249-271, 286-302 and 309-331 413999001468 Pfam match to entry PF01032 FecCD, FecCD transport family, score 320.4, E-value 2.3e-93 413999001469 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 413999001470 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999001471 Walker A/P-loop; other site 413999001472 ATP binding site [chemical binding]; other site 413999001473 Q-loop/lid; other site 413999001474 ABC transporter signature motif; other site 413999001475 Walker B; other site 413999001476 D-loop; other site 413999001477 H-loop/switch region; other site 413999001478 Pfam match to entry PF00005 ABC_tran, ABC transporter score 192.9, E-value 5.4e-55 413999001479 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001480 PS00211 ABC transporters family signature. 413999001481 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999001482 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999001483 ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251 413999001484 Walker A/P-loop; other site 413999001485 ATP binding site [chemical binding]; other site 413999001486 Q-loop/lid; other site 413999001487 ABC transporter signature motif; other site 413999001488 Walker B; other site 413999001489 D-loop; other site 413999001490 H-loop/switch region; other site 413999001491 6 probable transmembrane helices predicted for CBO0314 by TMHMM2.0 at aa 15-37, 58-80, 131-153, 160-177,243-265 and 272-291 413999001492 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 161.5, E-value 1.5e-45 413999001493 Pfam match to entry PF00005 ABC_tran, ABC transporter score 212.6, E-value 6e-61 413999001494 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001495 PS00211 ABC transporters family signature. 413999001496 Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325 413999001497 Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529 413999001498 Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742 413999001499 Pfam match to entry PF02742 Fe_dep_repr_C, Iron dependent repressor, metal binding and dimerisation domain, score 32.6, E-value 3.5e-08 413999001500 Pfam match to entry PF01325 Fe_dep_repress, Iron dependent repressor, N-terminal DNA binding domain, score 45.9, E-value 9.2e-11 413999001501 xanthine permease; Region: pbuX; TIGR03173 413999001502 Pfam match to entry PF00860 xan_ur_permease,Permease, score 380.3, E-value 2.1e-111 413999001503 12 probable transmembrane helices predicted for CBO0316 by TMHMM2.0 at aa 24-46, 56-73, 80-102, 106-128,135-157, 167-189, 196-218, 245-267, 279-301, 321-343,350-372 and 410-429 413999001504 PS01116 Xanthine/uracil permeases family signature. 413999001505 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999001506 active site 413999001507 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 75.6, E-value 1.1e-19 413999001508 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001509 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999001510 active site 413999001511 phosphorylation site [posttranslational modification] 413999001512 intermolecular recognition site; other site 413999001513 dimerization interface [polypeptide binding]; other site 413999001514 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999001515 DNA binding site [nucleotide binding] 413999001516 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 81.7, E-value 1.6e-21 413999001517 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 81.7, E-value 1.6e-21 413999001518 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001519 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080 413999001520 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001521 ATP binding site [chemical binding]; other site 413999001522 Mg2+ binding site [ion binding]; other site 413999001523 G-X-G motif; other site 413999001524 2 probable transmembrane helices predicted for CBO0319 by TMHMM2.0 at aa 12-34 and 38-57 413999001525 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 23.0, E-value 0.00039 413999001526 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 96.2,E-value 6.6e-26 413999001527 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281 413999001528 Pfam match to entry PF02673 BacA, Bacitracin resistance protein BacA, score 332.8, E-value 4.1e-97 413999001529 7 probable transmembrane helices predicted for CBO0320 by TMHMM2.0 at aa 12-34, 49-66, 91-113, 123-142,185-207, 227-249 and 261-283 413999001530 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999001531 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999001532 Walker A/P-loop; other site 413999001533 ATP binding site [chemical binding]; other site 413999001534 Q-loop/lid; other site 413999001535 ABC transporter signature motif; other site 413999001536 Walker B; other site 413999001537 D-loop; other site 413999001538 H-loop/switch region; other site 413999001539 Pfam match to entry PF00005 ABC_tran, ABC transporter score 199.7, E-value 4.9e-57 413999001540 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001541 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999001542 FtsX-like permease family; Region: FtsX; pfam02687 413999001543 10 probable transmembrane helices predicted for CBO0322 by TMHMM2.0 at aa 19-41, 56-78, 110-132, 152-174,195-217, 227-249, 282-304, 496-518, 552-574 and 584-606 413999001544 Pfam match to entry PF02687 FtsX, Predicted permease, score 44.6, E-value 2.3e-10 413999001545 LrgA family; Region: LrgA; pfam03788 413999001546 Pfam match to entry PF03788 LrgA, LrgA family,score 92.4, E-value 9.4e-25 413999001547 4 probable transmembrane helices predicted for CBO0324 by TMHMM2.0 at aa 7-24, 28-47, 59-81 and 85-107 413999001548 LrgB-like family; Region: LrgB; pfam04172 413999001549 6 probable transmembrane helices predicted for CBO0325 by TMHMM2.0 at aa 5-27, 32-54, 64-82, 91-113,147-169 and 205-227 413999001550 Pfam match to entry PF04172 LrgB, LrgB-like family,score 317.4, E-value 1.8e-92 413999001551 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001552 DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533 413999001553 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 22.8, E-value 4.5e-06 413999001554 DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533 413999001555 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868 413999001556 hypothetical protein; Provisional; Region: PRK13663 413999001557 4 probable transmembrane helices predicted for CBO0330 by TMHMM2.0 at aa 25-47, 52-71, 78-100 and 150-172 413999001558 5 probable transmembrane helices predicted for CBO0331 by TMHMM2.0 at aa 10-29, 36-53, 57-76, 88-110 and 125-144 413999001559 Accessory gene regulator B; Region: AgrB; pfam04647 413999001560 5 probable transmembrane helices predicted for CBO0332 by TMHMM2.0 at aa 31-53, 85-107, 109-128, 153-172 and 179-201 413999001561 cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223 413999001562 Domain of unknown function (DUF4118); Region: DUF4118; pfam13493 413999001563 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999001564 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999001565 metal binding site [ion binding]; metal-binding site 413999001566 active site 413999001567 I-site; other site 413999001568 c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206 413999001569 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999001570 Zn2+ binding site [ion binding]; other site 413999001571 Mg2+ binding site [ion binding]; other site 413999001572 5 probable transmembrane helices predicted for CBO0333 by TMHMM2.0 at aa 12-31, 51-73, 86-108, 128-150 and 163-180 413999001573 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 198.8, E-value 9e-57 413999001574 Pfam match to entry PF01966 HD, HD domain, score 102.2, E-value 1.1e-27 413999001575 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 413999001576 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999001577 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 45.1, E-value 1.6e-10 413999001578 4 probable transmembrane helices predicted for CBO0335 by TMHMM2.0 at aa 5-27, 48-70, 85-107 and 120-142 413999001579 Domain of unknown function (DUF4118); Region: DUF4118; pfam13493 413999001580 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 413999001581 PAS domain; Region: PAS; smart00091 413999001582 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999001583 dimer interface [polypeptide binding]; other site 413999001584 phosphorylation site [posttranslational modification] 413999001585 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001586 ATP binding site [chemical binding]; other site 413999001587 Mg2+ binding site [ion binding]; other site 413999001588 G-X-G motif; other site 413999001589 5 probable transmembrane helices predicted for CBO0336 by TMHMM2.0 at aa 21-41, 56-78, 91-110, 135-154 and 167-186 413999001590 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 65.9, E-value 9.2e-17 413999001591 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 142.0, E-value 1.1e-39 413999001592 5 probable transmembrane helices predicted for CBO0337 by TMHMM2.0 at aa 13-30, 37-56, 60-82, 89-111 and 126-143 413999001593 Accessory gene regulator B; Region: AgrB; pfam04647 413999001594 5 probable transmembrane helices predicted for CBO0338 by TMHMM2.0 at aa 40-62, 77-99, 104-126, 151-170 and 177-199 413999001595 cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223 413999001596 Domain of unknown function (DUF4118); Region: DUF4118; pfam13493 413999001597 PAS domain S-box; Region: sensory_box; TIGR00229 413999001598 PAS domain; Region: PAS_8; pfam13188 413999001599 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001600 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999001601 dimer interface [polypeptide binding]; other site 413999001602 phosphorylation site [posttranslational modification] 413999001603 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001604 ATP binding site [chemical binding]; other site 413999001605 Mg2+ binding site [ion binding]; other site 413999001606 G-X-G motif; other site 413999001607 5 probable transmembrane helices predicted for CBO0340 by TMHMM2.0 at aa 19-41, 56-78, 87-109, 135-154 and 167-184 413999001608 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 66.8, E-value 4.7e-17 413999001609 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 150.8, E-value 2.4e-42 413999001610 tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696 413999001611 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_II; cd01993 413999001612 Ligand Binding Site [chemical binding]; other site 413999001613 Pfam match to entry PF01171 ATP_bind3, PP-loop family, score 37.3, E-value 2.8e-11 413999001614 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999001615 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 413999001616 non-specific DNA binding site [nucleotide binding]; other site 413999001617 salt bridge; other site 413999001618 sequence-specific DNA binding site [nucleotide binding]; other site 413999001619 Cupin domain; Region: Cupin_2; pfam07883 413999001620 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 63.7, E-value 4.1e-16 413999001621 Predicted helix-turn-helix motif with score 1816.000, SD 5.37 at aa 47-68, sequence LTLKDLSEKTGLSISFLSQVEN 413999001622 Amino acid permease; Region: AA_permease_2; pfam13520 413999001623 12 probable transmembrane helices predicted for CBO0343 by TMHMM2.0 at aa 5-24, 34-56, 95-113, 123-140,153-175, 197-219, 232-254, 281-303, 330-352, 356-378,405-424 and 434-456 413999001624 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score 32.1, E-value 6.9e-09 413999001625 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 413999001626 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 413999001627 Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092 413999001628 active site 413999001629 Pfam match to entry PF00557 Peptidase_M24,metallopeptidase M24, score 160.6, E-value 2.8e-45 413999001630 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805 413999001631 Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122 413999001632 putative catalytic cysteine [active] 413999001633 C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178 413999001634 putative active site [active] 413999001635 metal binding site [ion binding]; metal-binding site 413999001636 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 697.2, E-value 8.1e-207 413999001637 PS00913 Iron-containing alcohol dehydrogenases signature 1. 413999001638 PS00060 Iron-containing alcohol dehydrogenases signature 2. 413999001639 Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; cl01811 413999001640 Protein of unknown function (DUF3793); Region: DUF3793; pfam12672 413999001641 1 probable transmembrane helix predicted for CBO0347 by TMHMM2.0 at aa 21-43 413999001642 Protein of unknown function (DUF3189); Region: DUF3189; pfam11385 413999001643 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 413999001644 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 413999001645 active site 413999001646 4 probable transmembrane helices predicted for CBO0350 by TMHMM2.0 at aa 28-50, 57-76, 128-145 and 152-170 413999001647 Pfam match to entry PF01569 PAP2, PAP2 superfamily,score 102.2, E-value 1.1e-27 413999001648 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 413999001649 Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944 413999001650 NodB motif; other site 413999001651 active site 413999001652 catalytic site [active] 413999001653 Zn binding site [ion binding]; other site 413999001654 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 137.1, E-value 3.3e-38 413999001655 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999001656 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001657 active site 413999001658 phosphorylation site [posttranslational modification] 413999001659 intermolecular recognition site; other site 413999001660 dimerization interface [polypeptide binding]; other site 413999001661 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999001662 DNA binding site [nucleotide binding] 413999001663 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 151.7, E-value 1.3e-42 413999001664 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 90.6, E-value 3.3e-24 413999001665 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001666 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999001667 dimerization interface [polypeptide binding]; other site 413999001668 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999001669 dimer interface [polypeptide binding]; other site 413999001670 phosphorylation site [posttranslational modification] 413999001671 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001672 ATP binding site [chemical binding]; other site 413999001673 Mg2+ binding site [ion binding]; other site 413999001674 G-X-G motif; other site 413999001675 2 probable transmembrane helices predicted for CBO0353 by TMHMM2.0 at aa 10-32 and 167-189 413999001676 Pfam match to entry PF00672 HAMP, HAMP domain,score 64.2, E-value 2.8e-16 413999001677 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 69.2, E-value 9.4e-18 413999001678 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 137.7, E-value 2.1e-38 413999001679 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001680 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999001681 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 413999001682 Putative rRNA methylase; Region: rRNA_methylase; pfam06962 413999001683 Uncharacterized conserved protein [Function unknown]; Region: COG0398 413999001684 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 413999001685 5 probable transmembrane helices predicted for CBO0356 by TMHMM2.0 at aa 10-28, 49-71, 86-108, 163-182 and 192-211 413999001686 Pfam match to entry PF00597 DedA, DedA family,score 14.5, E-value 0.00051 413999001687 CHASE4 domain; Region: CHASE4; pfam05228 413999001688 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999001689 dimerization interface [polypeptide binding]; other site 413999001690 PAS domain; Region: PAS_9; pfam13426 413999001691 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999001692 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999001693 metal binding site [ion binding]; metal-binding site 413999001694 active site 413999001695 I-site; other site 413999001696 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 413999001697 Pfam match to entry PF00563 EAL, EAL domain, score 376.1, E-value 3.8e-110 413999001698 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 175.3, E-value 1e-49 413999001699 Pfam match to entry PF00672 HAMP, HAMP domain,score 44.2, E-value 3e-10 413999001700 2 probable transmembrane helices predicted for CBO0357 by TMHMM2.0 at aa 10-29 and 264-281 413999001701 Pfam match to entry PF05228 CHASE4, CHASE4 domain,score 66.4, E-value 6.5e-17 413999001702 Putative amidase domain; Region: Amidase_6; pfam12671 413999001703 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999001704 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137 413999001705 11 probable transmembrane helices predicted for CBO0359 by TMHMM2.0 at aa 13-35, 53-75, 88-110, 125-142,163-185, 190-212, 281-303, 318-340, 352-374, 389-408 and 415-437 413999001706 Pfam match to entry PF01554 MatE, MatE, score 93.4,E-value 4.9e-25 413999001707 Pfam match to entry PF01554 MatE, MatE, score 127.2, E-value 3.3e-35 413999001708 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215 413999001709 Pfam match to entry PF01966 HD, HD domain, score 26.1, E-value 8.6e-05 413999001710 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 413999001711 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 413999001712 12 probable transmembrane helices predicted for CBO0361 by TMHMM2.0 at aa 7-29, 39-58, 63-81, 96-118,125-147, 167-189, 196-218, 238-260, 287-309, 319-338,350-372 and 377-394 413999001713 Pfam match to entry PF00999 Na_H_Exchanger,Sodium/hydrogen exchanger family, score 214.1, E-value 2.2e-61 413999001714 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001715 PS00217 Sugar transport proteins signature 2. 413999001716 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 413999001717 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 413999001718 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999001719 catalytic residue [active] 413999001720 Pfam match to entry PF00266 aminotran_5,Aminotransferase class-V, score -35.7, E-value 7e-08 413999001721 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 413999001722 Predicted membrane protein [Function unknown]; Region: COG2855 413999001723 11 probable transmembrane helices predicted for CBO0363 by TMHMM2.0 at aa 7-25, 30-49, 65-82, 92-111,120-142, 147-169, 178-200, 210-232, 253-272, 277-299 and 312-334 413999001724 Pfam match to entry PF03601 Cons_hypoth698,hypothetical protein 698, score 344.6, E-value 1.1e-100 413999001725 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 413999001726 active site 413999001727 6 probable transmembrane helices predicted for CBO0364 by TMHMM2.0 at aa 13-33, 53-75, 82-104, 126-148,161-180 and 185-207 413999001728 Pfam match to entry PF01569 PAP2, PAP2 superfamily,score 0.9, E-value 0.0029 413999001729 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999001730 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999001731 active site 413999001732 phosphorylation site [posttranslational modification] 413999001733 intermolecular recognition site; other site 413999001734 dimerization interface [polypeptide binding]; other site 413999001735 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999001736 DNA binding site [nucleotide binding] 413999001737 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 146.2, E-value 6e-41 413999001738 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 102.7, E-value 7.5e-28 413999001739 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999001740 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999001741 dimerization interface [polypeptide binding]; other site 413999001742 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999001743 dimer interface [polypeptide binding]; other site 413999001744 phosphorylation site [posttranslational modification] 413999001745 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999001746 ATP binding site [chemical binding]; other site 413999001747 Mg2+ binding site [ion binding]; other site 413999001748 G-X-G motif; other site 413999001749 2 probable transmembrane helices predicted for CBO0366 by TMHMM2.0 at aa 23-45 and 186-205 413999001750 Pfam match to entry PF00672 HAMP, HAMP domain,score 50.6, E-value 3.7e-12 413999001751 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 61.2, E-value 2.3e-15 413999001752 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 101.3, E-value 2e-27 413999001753 Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322 413999001754 Na binding site [ion binding]; other site 413999001755 13 probable transmembrane helices predicted for CBO0367 by TMHMM2.0 at aa 4-22, 43-65, 70-92, 123-145,155-177, 184-206, 230-252, 272-294, 318-340, 361-383,387-409, 416-433 and 443-465 413999001756 Pfam match to entry PF00474 SSF, Sodium:solute symporter family, score 47.2, E-value 3.9e-11 413999001757 electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945 413999001758 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 413999001759 SLBB domain; Region: SLBB; pfam10531 413999001760 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999001761 Pfam match to entry PF01512 Complex1_51K,Respiratory-chain NADH dehydrogenase 51 Kd subunit, score 149.7, E-value 5.4e-42 413999001762 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 23.7, E-value 4.6e-05 413999001763 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999001764 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999001765 NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116 413999001766 Pfam match to entry PF03116 NQR2_RnfD_RnfE, NQR2,RnfD, RnfE family, score 326.2, E-value 3.9e-95 413999001767 9 probable transmembrane helices predicted for CBO0369 by TMHMM2.0 at aa 20-42, 47-64, 96-118, 130-152,172-194, 199-221, 225-247, 260-277 and 287-309 413999001768 FMN-binding domain; Region: FMN_bind; cl01081 413999001769 1 probable transmembrane helix predicted for CBO0370 by TMHMM2.0 at aa 9-31 413999001770 Pfam match to entry PF04205 FMN_bind, FMN-binding domain, score 78.3, E-value 1.7e-20 413999001771 electron transport complex RsxE subunit; Provisional; Region: PRK12405 413999001772 Pfam match to entry PF02508 Rnf-Nqr, Rnf-Nqr subunit, membrane protein, score 239.7, E-value 4.4e-69 413999001773 5 probable transmembrane helices predicted for CBO0371 by TMHMM2.0 at aa 38-60, 67-89, 99-118, 131-153 and 168-190 413999001774 electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943 413999001775 Pfam match to entry PF02508 Rnf-Nqr, Rnf-Nqr subunit, membrane protein, score 286.1, E-value 4.7e-83 413999001776 6 probable transmembrane helices predicted for CBO0372 by TMHMM2.0 at aa 5-24, 37-59, 69-91, 98-120,130-152 and 169-191 413999001777 ferredoxin; Validated; Region: PRK07118 413999001778 CheD chemotactic sensory transduction; Region: CheD; cl00810 413999001779 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999001780 1 probable transmembrane helix predicted for CBO0373 by TMHMM2.0 at aa 4-26 413999001781 Pfam match to entry PF04060 FeS, Fe-S cluster, score 51.2, E-value 2.5e-12 413999001782 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 38.3, E-value 1.8e-08 413999001783 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999001784 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999001785 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 37.7, E-value 2.8e-08 413999001786 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999001787 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001788 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001789 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001790 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 48.1, E-value 2e-11 413999001791 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 35.9, E-value 9.6e-08 413999001792 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 13.2, E-value 0.0018 413999001793 Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456 413999001794 5 probable transmembrane helices predicted for CBO0375 by TMHMM2.0 at aa 12-34, 44-66, 79-98, 108-130 and 135-157 413999001795 Listerrria innocua Lin0431 is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911 413999001796 trimer interface [polypeptide binding]; other site 413999001797 1 probable transmembrane helix predicted for CBO0376 by TMHMM2.0 at aa 7-26 413999001798 Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477 413999001799 ApbE family; Region: ApbE; pfam02424 413999001800 Pfam match to entry PF02424 ApbE, ApbE family,score 252.8, E-value 4.8e-73 413999001801 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001802 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001803 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001804 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001805 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 48.5, E-value 1.6e-11 413999001806 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 36.6, E-value 5.8e-08 413999001807 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 46.1, E-value 8.2e-11 413999001808 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001809 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001810 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001811 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001812 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 53.5, E-value 4.9e-13 413999001813 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 73.5, E-value 4.5e-19 413999001814 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 60.8, E-value 3.2e-15 413999001815 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001816 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001817 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999001818 Leucine rich repeats (6 copies); Region: LRR_5; pfam13306 413999001819 Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532 413999001820 Leucine rich repeats (6 copies); Region: LRR_5; pfam13306 413999001821 Leucine rich repeats (6 copies); Region: LRR_5; pfam13306 413999001822 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 47.9, E-value 2.4e-11 413999001823 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 35.9, E-value 9.5e-08 413999001824 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 46.3, E-value 7.1e-11 413999001825 Predicted O-acyltransferase [General function prediction only]; Region: COG3274 413999001826 Acyltransferase family; Region: Acyl_transf_3; pfam01757 413999001827 Pfam match to entry PF01757 Acyl_transf_3,Acyltransferase, score -22.0, E-value 0.00024 413999001828 10 probable transmembrane helices predicted for CBO0382 by TMHMM2.0 at aa 17-36, 56-75, 96-115, 125-147,154-173, 188-205, 218-240, 250-272, 279-301 and 311-333 413999001829 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 413999001830 Bacterial Ig-like domain; Region: Big_5; pfam13205 413999001831 PBP superfamily domain; Region: PBP_like_2; cl17296 413999001832 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 16.8, E-value 0.02 413999001833 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001834 ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573 413999001835 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999001836 dimer interface [polypeptide binding]; other site 413999001837 conserved gate region; other site 413999001838 putative PBP binding loops; other site 413999001839 ABC-ATPase subunit interface; other site 413999001840 6 probable transmembrane helices predicted for CBO0385 by TMHMM2.0 at aa 13-35, 75-97, 110-132, 147-166,204-226 and 262-284 413999001841 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 59.9, E-value 5.7e-15 413999001842 phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974 413999001843 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999001844 dimer interface [polypeptide binding]; other site 413999001845 conserved gate region; other site 413999001846 putative PBP binding loops; other site 413999001847 ABC-ATPase subunit interface; other site 413999001848 6 probable transmembrane helices predicted for CBO0386 by TMHMM2.0 at aa 9-31, 69-91, 104-126, 131-153,195-217 and 249-271 413999001849 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 67.2, E-value 3.6e-17 413999001850 ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117 413999001851 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 413999001852 Walker A/P-loop; other site 413999001853 ATP binding site [chemical binding]; other site 413999001854 Q-loop/lid; other site 413999001855 ABC transporter signature motif; other site 413999001856 Walker B; other site 413999001857 D-loop; other site 413999001858 H-loop/switch region; other site 413999001859 Pfam match to entry PF00005 ABC_tran, ABC transporter score 192.6, E-value 6.4e-55 413999001860 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001861 PS00211 ABC transporters family signature. 413999001862 Soluble P-type ATPase [General function prediction only]; Region: COG4087 413999001863 amino acid transporter; Region: 2A0306; TIGR00909 413999001864 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score 60.6, E-value 3.5e-15 413999001865 12 probable transmembrane helices predicted for CBO0389 by TMHMM2.0 at aa 23-45, 49-71, 96-118, 143-165,170-192, 212-234, 247-269, 294-316, 347-364, 369-391,411-433 and 437-459 413999001866 sporulation lipoprotein, YhcN/YlaJ family; Region: spore_YhcN_YlaJ; TIGR02898 413999001867 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580 413999001868 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001869 Protein of unknown function DUF45; Region: DUF45; pfam01863 413999001870 Pfam match to entry PF01863 DUF45, Protein of unknown function DUF45, score 110.1, E-value 4.6e-30 413999001871 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999001872 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 413999001873 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 413999001874 dimer interface [polypeptide binding]; other site 413999001875 ssDNA binding site [nucleotide binding]; other site 413999001876 tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999001877 Pfam match to entry PF00436 SSB, Single-strand binding protein family, score 125.9, E-value 7.7e-35 413999001878 PS00735 Single-strand binding protein family signature 1. 413999001879 Predicted membrane protein [Function unknown]; Region: COG1971 413999001880 6 probable transmembrane helices predicted for CBO0394 by TMHMM2.0 at aa 7-26, 36-58, 63-85, 100-121,128-150 and 160-182 413999001881 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 413999001882 metal binding site 2 [ion binding]; metal-binding site 413999001883 putative DNA binding helix; other site 413999001884 metal binding site 1 [ion binding]; metal-binding site 413999001885 dimer interface [polypeptide binding]; other site 413999001886 structural Zn2+ binding site [ion binding]; other site 413999001887 Pfam match to entry PF01475 FUR, Ferric uptake regulator family, score 43.0, E-value 7.1e-10 413999001888 PS00190 Cytochrome c family heme-binding site signature. 413999001889 c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206 413999001890 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999001891 Zn2+ binding site [ion binding]; other site 413999001892 Mg2+ binding site [ion binding]; other site 413999001893 Pfam match to entry PF01966 HD, HD domain, score 92.5, E-value 8.6e-25 413999001894 Rhomboid family; Region: Rhomboid; pfam01694 413999001895 6 probable transmembrane helices predicted for CBO0398 by TMHMM2.0 at aa 159-181, 206-228, 241-258,262-284, 293-312 and 317-336 413999001896 Pfam match to entry PF01694 Rhomboid, Rhomboid family, score 169.1, E-value 7.5e-48 413999001897 Cache domain; Region: Cache_1; pfam02743 413999001898 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999001899 dimerization interface [polypeptide binding]; other site 413999001900 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999001901 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999001902 dimer interface [polypeptide binding]; other site 413999001903 putative CheW interface [polypeptide binding]; other site 413999001904 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 248.0, E-value 1.4e-71 413999001905 Pfam match to entry PF00672 HAMP, HAMP domain,score 50.6, E-value 3.6e-12 413999001906 2 probable transmembrane helices predicted for CBO0399 by TMHMM2.0 at aa 10-32 and 303-325 413999001907 Pfam match to entry PF02743 Cache, Cache domain,score 54.7, E-value 2.1e-13 413999001908 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001909 ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465 413999001910 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999001911 Walker A motif; other site 413999001912 ATP binding site [chemical binding]; other site 413999001913 Walker B motif; other site 413999001914 arginine finger; other site 413999001915 Peptidase family M41; Region: Peptidase_M41; pfam01434 413999001916 Pfam match to entry PF01434 Peptidase_M41,Peptidase M41, score 183.2, E-value 4.3e-52 413999001917 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999001918 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 280.1, E-value 2.9e-81 413999001919 PS00674 AAA-protein family signature. 413999001920 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001921 2 probable transmembrane helices predicted for CBO0400 by TMHMM2.0 at aa 7-29 and 103-121 413999001922 Protein of unknown function (DUF1232); Region: DUF1232; pfam06803 413999001923 RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278 413999001924 RNA/DNA hybrid binding site [nucleotide binding]; other site 413999001925 active site 413999001926 Pfam match to entry PF00075 rnaseH, RNase H, score 180.8, E-value 2.3e-51 413999001927 1 probable transmembrane helix predicted for CBO0403 by TMHMM2.0 at aa 5-27 413999001928 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999001929 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999001930 non-specific DNA binding site [nucleotide binding]; other site 413999001931 salt bridge; other site 413999001932 sequence-specific DNA binding site [nucleotide binding]; other site 413999001933 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999001934 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999001935 binding surface 413999001936 TPR motif; other site 413999001937 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999001938 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 42.7, E-value 8.9e-10 413999001939 Pfam match to entry PF00515 TPR, TPR Domain, score 2.9, E-value 1.7 413999001940 Pfam match to entry PF00515 TPR, TPR Domain, score 11.6, E-value 0.16 413999001941 Pfam match to entry PF00515 TPR, TPR Domain, score 6.4, E-value 0.66 413999001942 Pfam match to entry PF00515 TPR, TPR Domain, score 13.6, E-value 0.091 413999001943 Pfam match to entry PF00515 TPR, TPR Domain, score 1.6, E-value 2.4 413999001944 Helix-turn-helix domain; Region: HTH_19; pfam12844 413999001945 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999001946 Pfam match to entry PF00515 TPR, TPR Domain, score 2.6, E-value 1.8 413999001947 Pfam match to entry PF00515 TPR, TPR Domain, score 8.5, E-value 0.36 413999001948 Pfam match to entry PF00515 TPR, TPR Domain, score 1.2, E-value 2.7 413999001949 Pfam match to entry PF00515 TPR, TPR Domain, score 20.8, E-value 0.0035 413999001950 DJ-1 family protein; Region: not_thiJ; TIGR01383 413999001951 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 413999001952 conserved cys residue [active] 413999001953 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family, score 38.6, E-value 1.5e-08 413999001954 Domain of unknown function (DUF2935); Region: DUF2935; pfam11155 413999001955 Domain of unknown function (DUF2935); Region: DUF2935; pfam11155 413999001956 ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346 413999001957 Clp amino terminal domain; Region: Clp_N; pfam02861 413999001958 Clp amino terminal domain; Region: Clp_N; pfam02861 413999001959 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999001960 Walker A motif; other site 413999001961 ATP binding site [chemical binding]; other site 413999001962 Walker B motif; other site 413999001963 arginine finger; other site 413999001964 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999001965 Walker A motif; other site 413999001966 ATP binding site [chemical binding]; other site 413999001967 Walker B motif; other site 413999001968 arginine finger; other site 413999001969 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 413999001970 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain, score 59.4, E-value 8.3e-15 413999001971 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain, score 58.9, E-value 1.2e-14 413999001972 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 58.7, E-value 1.4e-14 413999001973 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001974 PS00870 Chaperonins clpA/B signature 1. 413999001975 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 5.0, E-value 0.00014 413999001976 PS00017 ATP/GTP-binding site motif A (P-loop). 413999001977 PS00871 Chaperonins clpA/B signature 2. 413999001978 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750 413999001979 catalytic triad [active] 413999001980 UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769 413999001981 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999001982 Domain of unknown function (DUF1727); Region: DUF1727; pfam08353 413999001983 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 35.3, E-value 3e-10 413999001984 Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482 413999001985 Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429 413999001986 Pfam match to entry PF01238 PMI_typeI,Phosphomannose isomerase type I, score -42.3, E-value 8.5e-08 413999001987 1 probable transmembrane helix predicted for CBO0413 by TMHMM2.0 at aa 7-26 413999001988 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001989 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK12554 413999001990 Pfam match to entry PF02673 BacA, Bacitracin resistance protein BacA, score 352.0, E-value 6.9e-103 413999001991 7 probable transmembrane helices predicted for CBO0414 by TMHMM2.0 at aa 15-37, 50-72, 92-111, 118-137,181-203, 224-246 and 261-283 413999001992 Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333 413999001993 Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753 413999001994 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 74.2, E-value 2.8e-19 413999001995 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999001996 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 413999001997 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 413999001998 putative acyl-acceptor binding pocket; other site 413999001999 1 probable transmembrane helix predicted for CBO0416 by TMHMM2.0 at aa 4-22 413999002000 Pfam match to entry PF01553 Acyltransferase,Acyltransferase, score 132.4, E-value 8.8e-37 413999002001 isopropylmalate/citramalate/homocitrate synthases; Region: LEU1_arch; TIGR02090 413999002002 Clostridium kluyveri Re-citrate synthase and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_Re_CS; cd07947 413999002003 active site 413999002004 catalytic residues [active] 413999002005 metal binding site [ion binding]; metal-binding site 413999002006 Pfam match to entry PF00682 HMGL-like, HMGL-like,score 22.0, E-value 5.4e-10 413999002007 aconitate hydratase; Validated; Region: PRK07229 413999002008 Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Bact; cd01585 413999002009 substrate binding site [chemical binding]; other site 413999002010 ligand binding site [chemical binding]; other site 413999002011 Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215 413999002012 substrate binding site [chemical binding]; other site 413999002013 Pfam match to entry PF00330 aconitase, Aconitase (aconitate hydratase), score 388.1, E-value 9.1e-114 413999002014 PS00450 Aconitase signature 1. 413999002015 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002016 PS01244 Aconitase signature 2. 413999002017 Pfam match to entry PF00694 Aconitase_C, Aconitase C-terminal domain, score 75.0, E-value 1.6e-19 413999002018 Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473 413999002019 tartrate dehydrogenase; Region: TTC; TIGR02089 413999002020 Pfam match to entry PF00180 isodh,Isocitrate/isopropylmalate dehydrogenase, score 532.9,E-value 2.3e-157 413999002021 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 413999002022 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 413999002023 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 413999002024 Walker A/P-loop; other site 413999002025 ATP binding site [chemical binding]; other site 413999002026 Q-loop/lid; other site 413999002027 ABC transporter signature motif; other site 413999002028 Walker B; other site 413999002029 D-loop; other site 413999002030 H-loop/switch region; other site 413999002031 Pfam match to entry PF00005 ABC_tran, ABC transporter score 228.1, E-value 1.4e-65 413999002032 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002033 PS00211 ABC transporters family signature. 413999002034 Permease; Region: Permease; cl00510 413999002035 Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553 413999002036 14 probable transmembrane helices predicted for CBO0421 by TMHMM2.0 at aa 5-27, 42-59, 64-86, 110-132,153-175, 190-212, 233-255, 303-325, 361-380, 395-417,438-460, 475-497, 526-543 and 547-569 413999002037 Pfam match to entry PF03553 Na_H_antiporter, Na+/H+ antiporter family, score 270.0, E-value 3.2e-78 413999002038 Uncharacterized conserved protein [Function unknown]; Region: COG2155 413999002039 Pfam match to entry PF04070 DUF378, Domain of unknown function (DUF378), score 135.1, E-value 1.4e-37 413999002040 2 probable transmembrane helices predicted for CBO0422 by TMHMM2.0 at aa 7-29 and 39-58 413999002041 Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919 413999002042 tetramerization interface [polypeptide binding]; other site 413999002043 active site 413999002044 Pfam match to entry PF02261 Asp_decarbox, Aspartate decarboxylase, score 251.9, E-value 9.3e-73 413999002045 Pantoate-beta-alanine ligase; Region: PanC; cd00560 413999002046 pantoate--beta-alanine ligase; Region: panC; TIGR00018 413999002047 active site 413999002048 ATP-binding site [chemical binding]; other site 413999002049 pantoate-binding site; other site 413999002050 HXXH motif; other site 413999002051 Pfam match to entry PF02569 Pantoate_ligase,Pantoate-beta-alanine ligase, score 475.1, E-value 5.9e-140 413999002052 Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557 413999002053 oligomerization interface [polypeptide binding]; other site 413999002054 active site 413999002055 metal binding site [ion binding]; metal-binding site 413999002056 Pfam match to entry PF02548 Pantoate_transf,Ketopantoate hydroxymethyltransferase, score 521.3,E-value 7.3e-154 413999002057 helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773 413999002058 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 413999002059 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002060 type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521 413999002061 Pfam match to entry PF00515 TPR, TPR Domain, score 25.1, E-value 0.00017 413999002062 Pfam match to entry PF00515 TPR, TPR Domain, score 10.5, E-value 0.21 413999002063 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999002064 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999002065 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 66.8, E-value 4.7e-17 413999002066 PS01081 Bacterial regulatory proteins, tetR family signature. 413999002067 Predicted helix-turn-helix motif with score 1898.000, SD 5.65 at aa 29-50, sequence TSLREIASAAGLTTGAIYHHFK 413999002068 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999002069 Pfam match to entry PF01495 HypB_UreG, HypB/UreG nucleotide-binding domain, score 148.4, E-value 1.4e-41 413999002070 Ferredoxin [Energy production and conversion]; Region: NapF; COG1145 413999002071 4Fe-4S binding domain; Region: Fer4; pfam00037 413999002072 NADPH-dependent glutamate synthase beta chain and related oxidoreductases [Amino acid transport and metabolism / General function prediction only]; Region: GltD; COG0493 413999002073 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999002074 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 37.8, E-value 2.7e-08 413999002075 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999002076 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 66.3, E-value 6.9e-17 413999002077 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 30.8, E-value 3.2e-06 413999002078 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375 413999002079 Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155 413999002080 Pfam match to entry PF01155 HypA, Hydrogenase expression/synthesis hypA family, score 60.1, E-value 5.1e-15 413999002081 7 probable transmembrane helices predicted for CBO0434 by TMHMM2.0 at aa 10-29, 38-57, 67-86, 153-175,190-212, 219-238 and 278-300 413999002082 helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785 413999002083 Family description; Region: UvrD_C_2; pfam13538 413999002084 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 413999002085 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 284.3, E-value 1.6e-82 413999002086 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002087 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 413999002088 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 413999002089 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999002090 dimer interface [polypeptide binding]; other site 413999002091 putative CheW interface [polypeptide binding]; other site 413999002092 2 probable transmembrane helices predicted for CBO0437 by TMHMM2.0 at aa 13-35 and 50-72 413999002093 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 159.4, E-value 6.6e-45 413999002094 peptidase T; Region: peptidase-T; TIGR01882 413999002095 M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892 413999002096 metal binding site [ion binding]; metal-binding site 413999002097 dimer interface [polypeptide binding]; other site 413999002098 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 188.6, E-value 1e-53 413999002099 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 413999002100 PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 413999002101 ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207 413999002102 active site 413999002103 nucleophile elbow; other site 413999002104 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase, score 107.3, E-value 3.2e-29 413999002105 1 probable transmembrane helix predicted for CBO0441 by TMHMM2.0 at aa 20-39 413999002106 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999002107 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 40.1, E-value 5.4e-09 413999002108 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_23; cd09011 413999002109 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 413999002110 Pfam match to entry PF00903 Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily, score 24.3, E-value 0.00029 413999002111 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999002112 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999002113 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999002114 1 probable transmembrane helix predicted for CBO0444 by TMHMM2.0 at aa 5-27 413999002115 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999002116 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 49.3, E-value 9e-12 413999002117 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 86.7, E-value 5.1e-23 413999002118 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 64.9, E-value 1.8e-16 413999002119 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 413999002120 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999002121 dimer interface [polypeptide binding]; other site 413999002122 conserved gate region; other site 413999002123 putative PBP binding loops; other site 413999002124 ABC-ATPase subunit interface; other site 413999002125 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 123.2, E-value 5.1e-34 413999002126 3 probable transmembrane helices predicted for CBO0445 by TMHMM2.0 at aa 15-37, 57-79 and 180-202 413999002127 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999002128 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 413999002129 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 413999002130 substrate binding pocket [chemical binding]; other site 413999002131 membrane-bound complex binding site; other site 413999002132 hinge residues; other site 413999002133 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, score 276.0, E-value 5.1e-80 413999002134 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 413999002135 1 probable transmembrane helix predicted for CBO0446 by TMHMM2.0 at aa 5-22 413999002136 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999002137 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999002138 S-adenosylmethionine binding site [chemical binding]; other site 413999002139 2 probable transmembrane helices predicted for CBO0447 by TMHMM2.0 at aa 17-39 and 49-71 413999002140 Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434 413999002141 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 413999002142 Pfam match to entry PF00563 EAL, EAL domain, score -61.1, E-value 1.2e-05 413999002143 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 413999002144 thiamine phosphate binding site [chemical binding]; other site 413999002145 active site 413999002146 pyrophosphate binding site [ion binding]; other site 413999002147 Pfam match to entry PF02581 TMP-TENI, Thiamine monophosphate synthase/TENI, score 267.1, E-value 2.4e-77 413999002148 4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170 413999002149 substrate binding site [chemical binding]; other site 413999002150 multimerization interface [polypeptide binding]; other site 413999002151 ATP binding site [chemical binding]; other site 413999002152 Pfam match to entry PF02110 HK,Hydroxyethylthiazole kinase, score 366.2, E-value 3.6e-107 413999002153 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 413999002154 dimer interface [polypeptide binding]; other site 413999002155 substrate binding site [chemical binding]; other site 413999002156 ATP binding site [chemical binding]; other site 413999002157 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 18.7, E-value 3.5e-05 413999002158 D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372 413999002159 D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820 413999002160 ATP-grasp domain; Region: ATP-grasp_4; cl17255 413999002161 Pfam match to entry PF01820 Dala_Dala_ligas, D-ala D-ala ligase, score 308.7, E-value 7.5e-90 413999002162 PS00843 D-alanine--D-alanine ligase signature 1. 413999002163 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 413999002164 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 413999002165 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999002166 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002167 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region, score 169.3, E-value 6.7e-48 413999002168 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 413999002169 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 413999002170 TM-ABC transporter signature motif; other site 413999002171 Pfam match to entry PF02653 BPD_transp_2,Branched-chain amino acid transport system / permease component, score 145.8, E-value 8e-41 413999002172 7 probable transmembrane helices predicted for CBO0454 by TMHMM2.0 at aa 7-29, 33-55, 60-82, 135-157,187-209, 224-246 and 253-275 413999002173 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 413999002174 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 413999002175 TM-ABC transporter signature motif; other site 413999002176 9 probable transmembrane helices predicted for CBO0455 by TMHMM2.0 at aa 9-26, 30-52, 57-79, 83-105,112-131, 158-180, 212-234, 249-271 and 284-301 413999002177 Pfam match to entry PF02653 BPD_transp_2,Branched-chain amino acid transport system / permease component, score 166.2, E-value 5.6e-47 413999002178 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 413999002179 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 413999002180 Walker A/P-loop; other site 413999002181 ATP binding site [chemical binding]; other site 413999002182 Q-loop/lid; other site 413999002183 ABC transporter signature motif; other site 413999002184 Walker B; other site 413999002185 D-loop; other site 413999002186 H-loop/switch region; other site 413999002187 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.7, E-value 3.1e-55 413999002188 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002189 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 413999002190 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 413999002191 Walker A/P-loop; other site 413999002192 ATP binding site [chemical binding]; other site 413999002193 Q-loop/lid; other site 413999002194 ABC transporter signature motif; other site 413999002195 Walker B; other site 413999002196 D-loop; other site 413999002197 H-loop/switch region; other site 413999002198 Pfam match to entry PF00005 ABC_tran, ABC transporter score 165.2, E-value 1.1e-46 413999002199 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002200 PS00211 ABC transporters family signature. 413999002201 Uncharacterized ArCR, COG2043; Region: DUF169; pfam02596 413999002202 Pfam match to entry PF02596 DUF169, Uncharacterized ArCR, COG2043, score 97.3, E-value 3.2e-26 413999002203 Uncharacterized conserved protein [Function unknown]; Region: COG2966 413999002204 Protein of unknown function (DUF1212); Region: DUF1212; pfam06738 413999002205 4 probable transmembrane helices predicted for CBO0459 by TMHMM2.0 at aa 127-149, 159-181, 186-208 and 228-250 413999002206 Protein of unknown function (DUF3815); Region: DUF3815; pfam12821 413999002207 5 probable transmembrane helices predicted for CBO0460 by TMHMM2.0 at aa 5-22, 27-49, 53-70, 82-101 and 116-138 413999002208 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999002209 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999002210 DNA-binding site [nucleotide binding]; DNA binding site 413999002211 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999002212 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999002213 homodimer interface [polypeptide binding]; other site 413999002214 catalytic residue [active] 413999002215 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 46.4, E-value 6.6e-11 413999002216 PS00043 Bacterial regulatory proteins, gntR family signature. 413999002217 Predicted helix-turn-helix motif with score 1104.000, SD 2.95 at aa 37-58, sequence PSTRELASMLKVSRNTIISAYE 413999002218 Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704 413999002219 Pfam match to entry PF04011 LemA, LemA family,score 296.1, E-value 4.5e-86 413999002220 1 probable transmembrane helix predicted for CBO0462 by TMHMM2.0 at aa 7-26 413999002221 Repair protein; Region: Repair_PSII; pfam04536 413999002222 2 probable transmembrane helices predicted for CBO0463 by TMHMM2.0 at aa 13-30 and 197-219 413999002223 Pfam match to entry PF04536 DUF477, Protein of unknown function (DUF477), score 100.0, E-value 4.7e-27 413999002224 Repair protein; Region: Repair_PSII; pfam04536 413999002225 2 probable transmembrane helices predicted for CBO0464 by TMHMM2.0 at aa 12-29 and 193-212 413999002226 Pfam match to entry PF04536 DUF477, Protein of unknown function (DUF477), score 91.5, E-value 1.7e-24 413999002227 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883 413999002228 nudix motif; other site 413999002229 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 45.7, E-value 1.1e-10 413999002230 PS00215 Mitochondrial energy transfer proteins signature. 413999002231 2 probable transmembrane helices predicted for CBO0466 by TMHMM2.0 at aa 7-29 and 44-63 413999002232 Protein of unknown function (DUF3816); Region: DUF3816; pfam12822 413999002233 5 probable transmembrane helices predicted for CBO0467 by TMHMM2.0 at aa 10-29, 36-58, 73-95, 108-130 and 140-162 413999002234 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999002235 S-adenosylmethionine binding site [chemical binding]; other site 413999002236 PS00041 Bacterial regulatory proteins, araC family signature. 413999002237 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999002238 salt bridge; other site 413999002239 non-specific DNA binding site [nucleotide binding]; other site 413999002240 sequence-specific DNA binding site [nucleotide binding]; other site 413999002241 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 29.9, E-value 6.3e-06 413999002242 Predicted helix-turn-helix motif with score 1599.000, SD 4.63 at aa 16-37, sequence MSLKELAEKINLTNANLSILKN 413999002243 4 probable transmembrane helices predicted for CBO0470 by TMHMM2.0 at aa 13-35, 45-64, 85-104 and 124-146 413999002244 1 probable transmembrane helix predicted for CBO0471 by TMHMM2.0 at aa 21-43 413999002245 DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420 413999002246 Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840 413999002247 active site 413999002248 metal binding site [ion binding]; metal-binding site 413999002249 DNA binding site [nucleotide binding] 413999002250 Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320 413999002251 Pfam match to entry PF00149 Metallophos,Calcineurin-like phosphoesterase, score 48.5, E-value 1.6e-11 413999002252 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002253 AAA domain; Region: AAA_23; pfam13476 413999002254 Walker A/P-loop; other site 413999002255 ATP binding site [chemical binding]; other site 413999002256 Q-loop/lid; other site 413999002257 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002258 ABC transporter signature motif; other site 413999002259 Walker B; other site 413999002260 D-loop; other site 413999002261 H-loop/switch region; other site 413999002262 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain, score 19.7, E-value 1.8e-05 413999002263 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002264 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 413999002265 ADP-ribose binding site [chemical binding]; other site 413999002266 dimer interface [polypeptide binding]; other site 413999002267 active site 413999002268 nudix motif; other site 413999002269 metal binding site [ion binding]; metal-binding site 413999002270 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 19.7, E-value 0.0054 413999002271 Uncharacterized conserved protein [Function unknown]; Region: COG1284 413999002272 Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588 413999002273 Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588 413999002274 Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035 413999002275 Pfam match to entry PF02588 DUF161, Uncharacterized BCR, YitT family COG1284, score 88.9, E-value 1.1e-23 413999002276 5 probable transmembrane helices predicted for CBO0475 by TMHMM2.0 at aa 12-31, 51-70, 77-94, 104-126 and 157-179 413999002277 Pfam match to entry PF02588 DUF161, Uncharacterized BCR, YitT family COG1284, score 66.4, E-value 6.4e-17 413999002278 Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561 413999002279 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999002280 dimerization interface [polypeptide binding]; other site 413999002281 putative DNA binding site [nucleotide binding]; other site 413999002282 putative Zn2+ binding site [ion binding]; other site 413999002283 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family, score 113.0, E-value 6.1e-31 413999002284 Predicted helix-turn-helix motif with score 1639.000, SD 4.77 at aa 60-81, sequence MCVCDISNLLNMTQSAVSHQLK 413999002285 PS00846 Bacterial regulatory proteins, arsR family signature. 413999002286 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 413999002287 Heavy-metal-associated domain; Region: HMA; pfam00403 413999002288 metal-binding site [ion binding] 413999002289 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999002290 Soluble P-type ATPase [General function prediction only]; Region: COG4087 413999002291 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 32.2, E-value 1.3e-06 413999002292 6 probable transmembrane helices predicted for CBO0478 by TMHMM2.0 at aa 136-153, 158-180, 358-380,395-417, 693-715 and 719-741 413999002293 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 256.3, E-value 4.4e-74 413999002294 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 91.5, E-value 1.8e-24 413999002295 PS00154 E1-E2 ATPases phosphorylation site. 413999002296 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002297 Domain of unknown function (DUF2935); Region: DUF2935; pfam11155 413999002298 Domain of unknown function (DUF2935); Region: DUF2935; pfam11155 413999002299 NYN ribonuclease and ATPase of PhoH family domains [General function prediction only]; Region: COG1875 413999002300 PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883 413999002301 putative active site [active] 413999002302 PhoH-like protein; Region: PhoH; pfam02562 413999002303 Pfam match to entry PF02562 PhoH, PhoH-like protein, score -21.7, E-value 1.6e-11 413999002304 Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992 413999002305 1 probable transmembrane helix predicted for CBO0484 by TMHMM2.0 at aa 17-39 413999002306 1 probable transmembrane helix predicted for CBO0485 by TMHMM2.0 at aa 7-25 413999002307 This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142 413999002308 putative FMN binding site [chemical binding]; other site 413999002309 NADPH bind site [chemical binding]; other site 413999002310 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 34.0, E-value 3.7e-07 413999002311 thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603 413999002312 bacteriocin biosynthesis cyclodehydratase domain; Region: cyclo_dehyd_2; TIGR03882 413999002313 YcaO-like family; Region: YcaO; pfam02624 413999002314 thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604 413999002315 CAAX protease self-immunity; Region: Abi; pfam02517 413999002316 6 probable transmembrane helices predicted for CBO0490 by TMHMM2.0 at aa 7-26, 41-58, 71-93, 108-129,150-167 and 177-199 413999002317 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 33.6, E-value 4.6e-07 413999002318 7 probable transmembrane helices predicted for CBO0491 by TMHMM2.0 at aa 4-26, 59-78, 93-115, 141-163,173-193, 200-219 and 223-240 413999002319 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999002320 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002321 Walker A/P-loop; other site 413999002322 ATP binding site [chemical binding]; other site 413999002323 Q-loop/lid; other site 413999002324 ABC transporter signature motif; other site 413999002325 Walker B; other site 413999002326 D-loop; other site 413999002327 H-loop/switch region; other site 413999002328 Pfam match to entry PF00005 ABC_tran, ABC transporter score 231.0, E-value 1.8e-66 413999002329 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002330 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999002331 PS00211 ABC transporters family signature. 413999002332 ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698 413999002333 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 413999002334 6 probable transmembrane helices predicted for CBO0493 by TMHMM2.0 at aa 25-47, 184-206, 227-249,264-286, 291-313 and 349-371 413999002335 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 413999002336 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 413999002337 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 413999002338 ABC-2 type transporter; Region: ABC2_membrane; cl17235 413999002339 6 probable transmembrane helices predicted for CBO0494 by TMHMM2.0 at aa 25-47, 190-209, 230-252,267-289, 296-318 and 352-374 413999002340 Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158 413999002341 Peptidase family M50; Region: Peptidase_M50; pfam02163 413999002342 active site 413999002343 putative substrate binding region [chemical binding]; other site 413999002344 5 probable transmembrane helices predicted for CBO0495 by TMHMM2.0 at aa 7-29, 51-70, 91-113, 123-140 and 182-204 413999002345 Pfam match to entry PF02163 Peptidase_M50,Peptidase M50, score 148.0, E-value 1.8e-41 413999002346 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999002347 Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055 413999002348 Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the...; Region: P_permease; cd01116 413999002349 transmembrane helices; other site 413999002350 Pfam match to entry PF02040 ArsB, Arsenical pump membrane protein, score -85.2, E-value 9.3e-08 413999002351 Pfam match to entry PF00939 Na_sulph_symp,Sodium:sulfate symporter transmembrane region, score -204.6, E-value 3.7e-06 413999002352 10 probable transmembrane helices predicted for CBO0497 by TMHMM2.0 at aa 4-25, 32-49, 59-81, 102-124,174-196, 233-266, 281-303, 324-346, 361-383 and 404-426 413999002353 1 probable transmembrane helix predicted for CBO0498 by TMHMM2.0 at aa 240-262 413999002354 tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121 413999002355 Pfam match to entry PF02390 Methyltransf_4,methyltransferase, score 135.4, E-value 1.1e-37 413999002356 Protein of unknown function (DUF3892); Region: DUF3892; pfam13031 413999002357 Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014 413999002358 dimer interface [polypeptide binding]; other site 413999002359 catalytic triad [active] 413999002360 peroxidatic and resolving cysteines [active] 413999002361 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family, score 81.7, E-value 1.6e-21 413999002362 PS01265 Tpx family signature. 413999002363 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565 413999002364 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999002365 NAD(P) binding site [chemical binding]; other site 413999002366 active site 413999002367 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 301.8, E-value 8.5e-88 413999002368 PS00061 Short-chain dehydrogenases/reductases family signature. 413999002369 Response regulator receiver domain; Region: Response_reg; pfam00072 413999002370 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002371 active site 413999002372 phosphorylation site [posttranslational modification] 413999002373 intermolecular recognition site; other site 413999002374 dimerization interface [polypeptide binding]; other site 413999002375 Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967 413999002376 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 73.3, E-value 5.2e-19 413999002377 CHAP domain; Region: CHAP; pfam05257 413999002378 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999002379 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999002380 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999002381 SH3 domain protein; Region: SH3_and_anchor; TIGR04211 413999002382 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999002383 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 413999002384 NlpC/P60 family; Region: NLPC_P60; pfam00877 413999002385 Pfam match to entry PF00877 NLPC_P60, NlpC/P60 family, score 159.3, E-value 7e-45 413999002386 Pfam match to entry PF05257 CHAP, CHAP domain,score 52.9, E-value 7.4e-13 413999002387 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 413999002388 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 413999002389 PS00120 Lipases, serine active site. 413999002390 PAS fold; Region: PAS_4; pfam08448 413999002391 Response regulator receiver domain; Region: Response_reg; pfam00072 413999002392 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002393 active site 413999002394 phosphorylation site [posttranslational modification] 413999002395 intermolecular recognition site; other site 413999002396 dimerization interface [polypeptide binding]; other site 413999002397 Hpt domain; Region: Hpt; pfam01627 413999002398 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 110.9, E-value 2.5e-30 413999002399 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999002400 Zn2+ binding site [ion binding]; other site 413999002401 Mg2+ binding site [ion binding]; other site 413999002402 Pfam match to entry PF01966 HD, HD domain, score 87.3, E-value 3.3e-23 413999002403 Cache domain; Region: Cache_1; pfam02743 413999002404 HAMP domain; Region: HAMP; pfam00672 413999002405 dimerization interface [polypeptide binding]; other site 413999002406 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999002407 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999002408 dimer interface [polypeptide binding]; other site 413999002409 putative CheW interface [polypeptide binding]; other site 413999002410 2 probable transmembrane helices predicted for CBO0508 by TMHMM2.0 at aa 20-42 and 291-313 413999002411 Pfam match to entry PF00672 HAMP, HAMP domain,score 43.3, E-value 5.6e-10 413999002412 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 59.9, E-value 5.6e-15 413999002413 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002414 active site 413999002415 phosphorylation site [posttranslational modification] 413999002416 intermolecular recognition site; other site 413999002417 dimerization interface [polypeptide binding]; other site 413999002418 Uncharacterized conserved protein (DUF2294); Region: DUF2294; cl02390 413999002419 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 90.8, E-value 3e-24 413999002420 seryl-tRNA synthetase; Provisional; Region: PRK05431 413999002421 Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403 413999002422 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 413999002423 motif 1; other site 413999002424 dimer interface [polypeptide binding]; other site 413999002425 active site 413999002426 motif 2; other site 413999002427 motif 3; other site 413999002428 Pfam match to entry PF02403 Seryl_tRNA_N,Seryl-tRNA synthetase N-terminal domain, score 52.2,E-value 1.2e-12 413999002429 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score 119.1, E-value 8.8e-33 413999002430 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999002431 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 413999002432 DEAD_2; Region: DEAD_2; pfam06733 413999002433 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 413999002434 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 413999002435 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002436 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999002437 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999002438 DNA-binding site [nucleotide binding]; DNA binding site 413999002439 TrkA-C domain; Region: TrkA_C; pfam02080 413999002440 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 51.0, E-value 2.7e-12 413999002441 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 34.3, E-value 3e-07 413999002442 Predicted helix-turn-helix motif with score 1583.000, SD 4.58 at aa 90-111, sequence SGRSTLASMYNVSPETIRRAVA 413999002443 N(5)-(carboxyethyl)ornithine synthase; Region: ceo_syn; cd12181 413999002444 putative active site [active] 413999002445 putative ligand binding site [chemical binding]; other site 413999002446 putative NAD(P) binding site [chemical binding]; other site 413999002447 Pfam match to entry PF05222 AlaDh_PNT_N, Alanine dehydrogenase/PNT, N-terminal domain, score 65.2, E-value 1.4e-16 413999002448 Pfam match to entry PF01262 AlaDh_PNT_C, Alanine dehydrogenase/PNT, C-terminal domain, score 32.5, E-value 3.6e-10 413999002449 Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874 413999002450 Hemerythrin; Region: Hemerythrin; cd12107 413999002451 Fe binding site [ion binding]; other site 413999002452 Pfam match to entry PF01814 Hemerythrin,Hemerythrin, score 85.4, E-value 1.2e-22 413999002453 Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605 413999002454 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 413999002455 Pfam match to entry PF02777 sodfe_C, Iron/manganese superoxide dismutases, C-terminal domain, score 55.5,E-value 1.2e-13 413999002456 Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237 413999002457 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 28.3, E-value 1.8e-05 413999002458 PS00141 Eukaryotic and viral aspartyl proteases active site. 413999002459 1 probable transmembrane helix predicted for CBO0523 by TMHMM2.0 at aa 15-46 413999002460 Amino acid permease; Region: AA_permease_2; pfam13520 413999002461 13 probable transmembrane helices predicted for CBO0524 by TMHMM2.0 at aa 37-59, 64-86, 119-141, 146-165,170-192, 213-232, 252-274, 281-303, 307-329, 346-368,373-395, 408-427 and 432-451 413999002462 1 probable transmembrane helix predicted for CBO0525 by TMHMM2.0 at aa 7-26 413999002463 AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404 413999002464 AsnC family; Region: AsnC_trans_reg; pfam01037 413999002465 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family, score 92.9, E-value 6.9e-25 413999002466 Predicted helix-turn-helix motif with score 1238.000, SD 3.40 at aa 25-46, sequence TPFLEIARKCHVSGGTIHVRMK 413999002467 3 probable transmembrane helices predicted for CBO0527 by TMHMM2.0 at aa 7-29, 38-60 and 65-87 413999002468 transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905 413999002469 Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316 413999002470 12 probable transmembrane helices predicted for CBO0528 by TMHMM2.0 at aa 13-35, 45-67, 88-110, 125-144,157-179, 194-216, 229-251, 266-297, 328-345, 355-377,390-412 and 416-433 413999002471 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score 60.8, E-value 3.2e-15 413999002472 transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905 413999002473 Spore germination protein; Region: Spore_permease; cl17796 413999002474 12 probable transmembrane helices predicted for CBO0529 by TMHMM2.0 at aa 12-31, 46-68, 89-111, 126-148,153-175, 195-217, 230-252, 276-298, 328-347, 357-379,386-408 and 412-434 413999002475 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score 105.1, E-value 1.4e-28 413999002476 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663 413999002477 Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645 413999002478 trimer interface [polypeptide binding]; other site 413999002479 putative metal binding site [ion binding]; other site 413999002480 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 4.6,E-value 27 413999002481 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 15.7,E-value 0.12 413999002482 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 16.2,E-value 0.08 413999002483 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.0,E-value 6.1 413999002484 Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753 413999002485 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 57.0, E-value 4.3e-14 413999002486 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 413999002487 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474 413999002488 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999002489 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 413999002490 Soluble P-type ATPase [General function prediction only]; Region: COG4087 413999002491 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 413999002492 Pfam match to entry PF00689 Cation_ATPase_C, Cation transporting ATPase, C-terminus, score 127.7, E-value 2.3e-35 413999002493 8 probable transmembrane helices predicted for CBO0532 by TMHMM2.0 at aa 54-76, 81-98, 247-265, 275-297,673-695, 742-764, 814-836 and 849-866 413999002494 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 81.0, E-value 2.5e-21 413999002495 PS00154 E1-E2 ATPases phosphorylation site. 413999002496 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 354.3, E-value 1.3e-103 413999002497 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus, score 96.5, E-value 5.6e-26 413999002498 Chromate transporter; Region: Chromate_transp; pfam02417 413999002499 5 probable transmembrane helices predicted for CBO0533 by TMHMM2.0 at aa 7-29, 78-100, 112-131, 135-152 and 159-176 413999002500 Pfam match to entry PF02417 Chromate_transp,Chromate transporter score 130.0, E-value 4.5e-36 413999002501 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999002502 Chromate transporter; Region: Chromate_transp; pfam02417 413999002503 Pfam match to entry PF02417 Chromate_transp,Chromate transporter score 126.5, E-value 5.1e-35 413999002504 4 probable transmembrane helices predicted for CBO0534 by TMHMM2.0 at aa 7-29, 77-99, 106-128 and 143-172 413999002505 PemK-like protein; Region: PemK; pfam02452 413999002506 Pfam match to entry PF02452 PemK, PemK-like protein, score 81.1, E-value 2.4e-21 413999002507 Protein of unknown function (DUF327); Region: DUF327; pfam03885 413999002508 Pfam match to entry PF03885 DUF327, Protein of unknown function (DUF327), score 58.0, E-value 2.1e-14 413999002509 NAD synthetase; Reviewed; Region: nadE; PRK02628 413999002510 Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570 413999002511 multimer interface [polypeptide binding]; other site 413999002512 active site 413999002513 catalytic triad [active] 413999002514 protein interface 1 [polypeptide binding]; other site 413999002515 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 413999002516 homodimer interface [polypeptide binding]; other site 413999002517 NAD binding pocket [chemical binding]; other site 413999002518 ATP binding pocket [chemical binding]; other site 413999002519 Mg binding site [ion binding]; other site 413999002520 active-site loop [active] 413999002521 Pfam match to entry PF02540 NAD_synthase, NAD synthase, score 211.3, E-value 1.5e-60 413999002522 Pfam match to entry PF00795 CN_hydrolase,Carbon-nitrogen hydrolase, score 2.2, E-value 5.5e-08 413999002523 Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585 413999002524 2 probable transmembrane helices predicted for CBO0538 by TMHMM2.0 at aa 7-29 and 49-71 413999002525 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 413999002526 Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403 413999002527 1 probable transmembrane helix predicted for CBO0539 by TMHMM2.0 at aa 7-29 413999002528 Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family, score 240.6, E-value 2.4e-69 413999002529 CAAX protease self-immunity; Region: Abi; pfam02517 413999002530 6 probable transmembrane helices predicted for CBO0541 by TMHMM2.0 at aa 13-35, 50-72, 93-110, 140-162,175-207 and 227-249 413999002531 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 86.6, E-value 5.2e-23 413999002532 PS00043 Bacterial regulatory proteins, gntR family signature. 413999002533 Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011 413999002534 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 413999002535 Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087 413999002536 active site 413999002537 Pfam match to entry PF05195 AMP_N, Aminopeptidase P, N-terminal domain, score 58.8, E-value 1.3e-14 413999002538 Pfam match to entry PF00557 Peptidase_M24,metallopeptidase M24, score 200.8, E-value 2.1e-57 413999002539 5 probable transmembrane helices predicted for CBO0543 by TMHMM2.0 at aa 4-23, 30-52, 67-86, 93-112 and 122-144 413999002540 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999002541 sequence-specific DNA binding site [nucleotide binding]; other site 413999002542 salt bridge; other site 413999002543 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 413999002544 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999002545 Coenzyme A binding pocket [chemical binding]; other site 413999002546 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 44.5, E-value 2.5e-10 413999002547 NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251 413999002548 Pfam match to entry PF04324 fer2_BFD, BFD-like [2Fe-2S] binding domain, score 62.1, E-value 1.2e-15 413999002549 1 probable transmembrane helix predicted for CBO0546 by TMHMM2.0 at aa 10-32 413999002550 1 probable transmembrane helix predicted for CBO0547 by TMHMM2.0 at aa 5-24 413999002551 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 413999002552 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 413999002553 1 probable transmembrane helix predicted for CBO0548 by TMHMM2.0 at aa 5-24 413999002554 Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966 413999002555 Carbon starvation protein CstA; Region: CstA; pfam02554 413999002556 C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722 413999002557 Pfam match to entry PF02554 CstA, Carbon starvation protein CstA, score 314.3, E-value 1.5e-91 413999002558 14 probable transmembrane helices predicted for CBO0550 by TMHMM2.0 at aa 5-22, 77-99, 133-155, 165-187,194-213, 223-245, 250-272, 287-309, 326-348, 372-394,423-445, 449-471, 478-500 and 510-532 413999002559 Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922 413999002560 3 probable transmembrane helices predicted for CBO0551 by TMHMM2.0 at aa 10-32, 53-70 and 75-97 413999002561 Cache domain; Region: Cache_1; pfam02743 413999002562 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999002563 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999002564 dimer interface [polypeptide binding]; other site 413999002565 putative CheW interface [polypeptide binding]; other site 413999002566 2 probable transmembrane helices predicted for CBO0552 by TMHMM2.0 at aa 10-32 and 280-302 413999002567 Pfam match to entry PF02743 Cache, Cache domain,score 89.6, E-value 6.5e-24 413999002568 Pfam match to entry PF00672 HAMP, HAMP domain,score 28.3, E-value 1.9e-05 413999002569 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 112.4, E-value 9e-31 413999002570 Pfam match to entry PF00005 ABC_tran, ABC transporter score 118.6, E-value 1.2e-32 413999002571 PS00211 ABC transporters family signature. 413999002572 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002573 Pfam match to entry PF00005 ABC_tran, ABC transporter score 98.5, E-value 1.4e-26 413999002574 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002575 Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970 413999002576 large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567 413999002577 Pfam match to entry PF01741 MscL, Large-conductance mechanosensitive channel, MscL, score 202.0, E-value 9.9e-58 413999002578 3 probable transmembrane helices predicted for CBO0555 by TMHMM2.0 at aa 15-34, 41-58 and 73-95 413999002579 Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515 413999002580 6 probable transmembrane helices predicted for CBO0556 by TMHMM2.0 at aa 28-45, 55-77, 90-112, 122-144,151-173 and 183-205 413999002581 1 probable transmembrane helix predicted for CBO0557 by TMHMM2.0 at aa 20-42 413999002582 SEC-C motif; Region: SEC-C; pfam02810 413999002583 Pfam match to entry PF02810 SEC-C, SEC-C motif,score 32.5, E-value 1e-06 413999002584 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999002585 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999002586 DNA-binding site [nucleotide binding]; DNA binding site 413999002587 gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740 413999002588 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999002589 Walker A/P-loop; other site 413999002590 ATP binding site [chemical binding]; other site 413999002591 Q-loop/lid; other site 413999002592 ABC transporter signature motif; other site 413999002593 Walker B; other site 413999002594 D-loop; other site 413999002595 H-loop/switch region; other site 413999002596 Pfam match to entry PF00005 ABC_tran, ABC transporter score 129.0, E-value 9.4e-36 413999002597 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002598 6 probable transmembrane helices predicted for CBO0560 by TMHMM2.0 at aa 12-31, 41-63, 92-114, 134-156,169-191 and 225-247 413999002599 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 413999002600 ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300 413999002601 Walker A/P-loop; other site 413999002602 ATP binding site [chemical binding]; other site 413999002603 Q-loop/lid; other site 413999002604 ABC transporter signature motif; other site 413999002605 Walker B; other site 413999002606 D-loop; other site 413999002607 H-loop/switch region; other site 413999002608 TOBE domain; Region: TOBE_2; pfam08402 413999002609 Pfam match to entry PF00005 ABC_tran, ABC transporter score 219.6, E-value 5e-63 413999002610 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002611 PS00211 ABC transporters family signature. 413999002612 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 413999002613 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999002614 dimer interface [polypeptide binding]; other site 413999002615 conserved gate region; other site 413999002616 putative PBP binding loops; other site 413999002617 ABC-ATPase subunit interface; other site 413999002618 6 probable transmembrane helices predicted for CBO0562 by TMHMM2.0 at aa 48-70, 102-124, 136-158,185-207, 236-258 and 284-306 413999002619 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 50.2, E-value 4.7e-12 413999002620 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999002621 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 413999002622 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999002623 dimer interface [polypeptide binding]; other site 413999002624 conserved gate region; other site 413999002625 putative PBP binding loops; other site 413999002626 ABC-ATPase subunit interface; other site 413999002627 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 413999002628 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 413999002629 7 probable transmembrane helices predicted for CBO0563 by TMHMM2.0 at aa 7-29, 66-88, 100-122, 126-148,182-204, 231-253 and 266-288 413999002630 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 78.4, E-value 1.5e-20 413999002631 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999002632 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 54.4, E-value 2.7e-13 413999002633 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 413999002634 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999002635 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999002636 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 32.9, E-value 7.9e-07 413999002637 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 36.7, E-value 5.6e-08 413999002638 PS00041 Bacterial regulatory proteins, araC family signature. 413999002639 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 413999002640 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 413999002641 9 probable transmembrane helices predicted for CBO0565 by TMHMM2.0 at aa 7-29, 44-66, 73-95, 151-170,191-213, 223-245, 258-280, 333-355 and 360-382 413999002642 Pfam match to entry PF00375 SDF,Sodium:dicarboxylate symporter family, score 85.7, E-value 9.6e-23 413999002643 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002644 1 probable transmembrane helix predicted for CBO0566 by TMHMM2.0 at aa 9-31 413999002645 Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418 413999002646 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999002647 Zn2+ binding site [ion binding]; other site 413999002648 Mg2+ binding site [ion binding]; other site 413999002649 Pfam match to entry PF01966 HD, HD domain, score 43.3, E-value 5.7e-10 413999002650 ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575 413999002651 CAAX protease self-immunity; Region: Abi; pfam02517 413999002652 10 probable transmembrane helices predicted for CBO0570 by TMHMM2.0 at aa 12-31, 41-59, 71-93, 99-118,139-161, 176-198, 218-237, 241-263, 270-292 and 296-318 413999002653 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 58.3, E-value 1.7e-14 413999002654 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 413999002655 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 413999002656 Pfam match to entry PF00805 Pentapeptide,Pentapeptide repeats (8 copies), score 49.4, E-value 8.2e-12 413999002657 Pfam match to entry PF03692 UPF0153,Uncharacterised protein family (UPF0153), score 3.9,E-value 0.0029 413999002658 The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human...; Region: tRNA_bindingDomain; cl00320 413999002659 putative tRNA-binding site [nucleotide binding]; other site 413999002660 Pfam match to entry PF01588 tRNA_bind, tRNA binding domain, score 75.0, E-value 1.6e-19 413999002661 signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227 413999002662 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 413999002663 Catalytic site [active] 413999002664 Pfam match to entry PF00461 Peptidase_S26, Signal peptidase I, score 61.0, E-value 2.8e-15 413999002665 1 probable transmembrane helix predicted for CBO0574 by TMHMM2.0 at aa 10-32 413999002666 PS00760 Signal peptidases I lysine active site. 413999002667 PS00761 Signal peptidases I signature 3. 413999002668 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002669 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 413999002670 active site 413999002671 phosphorylation site [posttranslational modification] 413999002672 intermolecular recognition site; other site 413999002673 dimerization interface [polypeptide binding]; other site 413999002674 LytTr DNA-binding domain; Region: LytTR; smart00850 413999002675 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 36.4, E-value 7e-08 413999002676 Pfam match to entry PF04397 LytTR, LytTr DNA-binding domain, score 93.7, E-value 3.9e-25 413999002677 Cys-rich peptide, Clo7bot family; Region: Clo7Bot_mod_Cys; TIGR04333 413999002678 Cys-rich peptide, Clo7bot family; Region: Clo7Bot_mod_Cys; TIGR04333 413999002679 1 probable transmembrane helix predicted for CBO0579 by TMHMM2.0 at aa 13-35 413999002680 radical SAM/SPASM domain Clo7bot peptide maturase; Region: rSAM_Clo7bot; TIGR04334 413999002681 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999002682 FeS/SAM binding site; other site 413999002683 radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085 413999002684 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 81.3, E-value 2.1e-21 413999002685 Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485 413999002686 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999002687 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999002688 Coenzyme A binding pocket [chemical binding]; other site 413999002689 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999002690 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999002691 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002692 Walker A/P-loop; other site 413999002693 ATP binding site [chemical binding]; other site 413999002694 Q-loop/lid; other site 413999002695 ABC transporter signature motif; other site 413999002696 Walker B; other site 413999002697 D-loop; other site 413999002698 H-loop/switch region; other site 413999002699 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 129.1, E-value 8.6e-36 413999002700 5 probable transmembrane helices predicted for CBO0583 by TMHMM2.0 at aa 21-43, 58-76, 133-155, 159-178 and 245-267 413999002701 Pfam match to entry PF00005 ABC_tran, ABC transporter score 175.4, E-value 9.9e-50 413999002702 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002703 PS00211 ABC transporters family signature. 413999002704 1 probable transmembrane helix predicted for CBO0584 by TMHMM2.0 at aa 4-21 413999002705 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999002706 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999002707 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 22.0, E-value 0.0014 413999002708 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 413999002709 ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591 413999002710 FtsX-like permease family; Region: FtsX; pfam02687 413999002711 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 413999002712 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999002713 FtsX-like permease family; Region: FtsX; pfam02687 413999002714 10 probable transmembrane helices predicted for CBO0586 by TMHMM2.0 at aa 17-36, 253-275, 299-321,341-360, 387-405, 415-437, 465-487, 691-713, 739-761 and 784-803 413999002715 Pfam match to entry PF02687 FtsX, Predicted permease, score 69.8, E-value 6.2e-18 413999002716 Pfam match to entry PF02687 FtsX, Predicted permease, score 70.7, E-value 3.3e-18 413999002717 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999002718 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999002719 Walker A/P-loop; other site 413999002720 ATP binding site [chemical binding]; other site 413999002721 Q-loop/lid; other site 413999002722 ABC transporter signature motif; other site 413999002723 Walker B; other site 413999002724 D-loop; other site 413999002725 H-loop/switch region; other site 413999002726 Pfam match to entry PF00005 ABC_tran, ABC transporter score 189.4, E-value 5.9e-54 413999002727 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002728 PS00211 ABC transporters family signature. 413999002729 EDD domain protein, DegV family; Region: DegV; TIGR00762 413999002730 Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645 413999002731 Pfam match to entry PF02645 DUF194, Uncharacterized protein, DegV family COG1307, score 232.8, E-value 5.1e-67 413999002732 hypothetical protein; Provisional; Region: PRK04164 413999002733 2 probable transmembrane helices predicted for CBO0591 by TMHMM2.0 at aa 4-26 and 33-55 413999002734 1 probable transmembrane helix predicted for CBO0592 by TMHMM2.0 at aa 4-26 413999002735 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368 413999002736 Sulfatase; Region: Sulfatase; pfam00884 413999002737 5 probable transmembrane helices predicted for CBO0593 by TMHMM2.0 at aa 13-30, 40-62, 69-91, 95-117 and 149-171 413999002738 Pfam match to entry PF00884 Sulfatase, Sulfatase,score 68.0, E-value 2.1e-17 413999002739 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999002740 psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974 413999002741 Walker A motif; other site 413999002742 ATP binding site [chemical binding]; other site 413999002743 Walker B motif; other site 413999002744 arginine finger; other site 413999002745 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999002746 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 58.0, E-value 2.1e-14 413999002747 Predicted helix-turn-helix motif with score 1962.000, SD 5.87 at aa 434-455, sequence GNIVQASELLGISRATIYRKIN 413999002748 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999002749 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 385.9, E-value 4.3e-113 413999002750 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999002751 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 413999002752 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 413999002753 Nucleoside recognition; Region: Gate; pfam07670 413999002754 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 413999002755 Pfam match to entry PF01773 Nucleoside_tra2, Na+ dependent nucleoside transporter score 665.2, E-value 3.5e-197 413999002756 8 probable transmembrane helices predicted for CBO0595 by TMHMM2.0 at aa 4-21, 28-47, 91-113, 171-193,253-275, 282-304, 349-371 and 384-406 413999002757 1 probable transmembrane helix predicted for CBO0596 by TMHMM2.0 at aa 20-42 413999002758 asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932 413999002759 EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318 413999002760 putative dimer interface [polypeptide binding]; other site 413999002761 putative anticodon binding site; other site 413999002762 Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776 413999002763 homodimer interface [polypeptide binding]; other site 413999002764 motif 1; other site 413999002765 motif 2; other site 413999002766 active site 413999002767 motif 3; other site 413999002768 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 38.5, E-value 1.5e-08 413999002769 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N), score 447.7, E-value 1e-131 413999002770 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999002771 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999002772 Predicted transcriptional regulators [Transcription]; Region: COG1695 413999002773 Transcriptional regulator PadR-like family; Region: PadR; cl17335 413999002774 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family, score 44.1, E-value 3.2e-10 413999002775 Protein of unknown function (DUF2812); Region: DUF2812; pfam11193 413999002776 2 probable transmembrane helices predicted for CBO0599 by TMHMM2.0 at aa 120-142 and 146-168 413999002777 LytTr DNA-binding domain; Region: LytTR; smart00850 413999002778 Pfam match to entry PF04397 LytTR, LytTr DNA-binding domain, score 75.5, E-value 1.2e-19 413999002779 4 probable transmembrane helices predicted for CBO0601 by TMHMM2.0 at aa 7-26, 30-47, 49-68 and 78-97 413999002780 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999002781 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999002782 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999002783 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708 413999002784 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 30.0, E-value 5.8e-06 413999002785 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 22-43, sequence LTPEVIANKCGYSVFHFSRIFN 413999002786 PS00041 Bacterial regulatory proteins, araC family signature. 413999002787 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 26.9, E-value 4.9e-05 413999002788 CAAX protease self-immunity; Region: Abi; pfam02517 413999002789 8 probable transmembrane helices predicted for CBO0603 by TMHMM2.0 at aa 30-52, 67-89, 110-132, 142-159,171-193, 203-225, 238-260 and 275-297 413999002790 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 57.3, E-value 3.5e-14 413999002791 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999002792 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999002793 non-specific DNA binding site [nucleotide binding]; other site 413999002794 salt bridge; other site 413999002795 sequence-specific DNA binding site [nucleotide binding]; other site 413999002796 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 67.6, E-value 2.7e-17 413999002797 Predicted helix-turn-helix motif with score 1972.000, SD 5.90 at aa 16-37, sequence LSQDELGSKLNVSRQTISKWEL 413999002798 1 probable transmembrane helix predicted for CBO0604 by TMHMM2.0 at aa 103-125 413999002799 Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532 413999002800 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999002801 Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532 413999002802 1 probable transmembrane helix predicted for CBO0606 by TMHMM2.0 at aa 5-22 413999002803 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999002804 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999002805 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002806 active site 413999002807 phosphorylation site [posttranslational modification] 413999002808 intermolecular recognition site; other site 413999002809 dimerization interface [polypeptide binding]; other site 413999002810 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999002811 DNA binding site [nucleotide binding] 413999002812 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 124.5, E-value 2e-34 413999002813 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 70.6, E-value 3.4e-18 413999002814 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999002815 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999002816 dimerization interface [polypeptide binding]; other site 413999002817 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999002818 dimer interface [polypeptide binding]; other site 413999002819 phosphorylation site [posttranslational modification] 413999002820 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999002821 ATP binding site [chemical binding]; other site 413999002822 Mg2+ binding site [ion binding]; other site 413999002823 G-X-G motif; other site 413999002824 3 probable transmembrane helices predicted for CBO0608 by TMHMM2.0 at aa 7-29, 135-154 and 166-188 413999002825 Pfam match to entry PF00672 HAMP, HAMP domain,score 49.4, E-value 8.4e-12 413999002826 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 58.8, E-value 1.2e-14 413999002827 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 88.5,E-value 1.4e-23 413999002828 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876 413999002829 D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557 413999002830 Pfam match to entry PF02557 VanY,D-alanyl-D-alanine carboxypeptidase, score 158.7, E-value 1.1e-44 413999002831 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999002832 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002833 active site 413999002834 phosphorylation site [posttranslational modification] 413999002835 intermolecular recognition site; other site 413999002836 dimerization interface [polypeptide binding]; other site 413999002837 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999002838 DNA binding site [nucleotide binding] 413999002839 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 122.9, E-value 6.1e-34 413999002840 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 83.2, E-value 5.5e-22 413999002841 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999002842 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999002843 dimer interface [polypeptide binding]; other site 413999002844 phosphorylation site [posttranslational modification] 413999002845 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999002846 ATP binding site [chemical binding]; other site 413999002847 Mg2+ binding site [ion binding]; other site 413999002848 G-X-G motif; other site 413999002849 2 probable transmembrane helices predicted for CBO0611 by TMHMM2.0 at aa 17-39 and 59-81 413999002850 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 65.7, E-value 1e-16 413999002851 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 112.6, E-value 7.9e-31 413999002852 Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303 413999002853 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425 413999002854 8 probable transmembrane helices predicted for CBO0612 by TMHMM2.0 at aa 7-24, 71-93, 98-120, 135-157,170-192, 202-224, 255-277 and 302-324 413999002855 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 413999002856 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999002857 active site 413999002858 phosphorylation site [posttranslational modification] 413999002859 intermolecular recognition site; other site 413999002860 dimerization interface [polypeptide binding]; other site 413999002861 YcbB domain; Region: YcbB; pfam08664 413999002862 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 71.6, E-value 1.7e-18 413999002863 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999002864 ATP binding site [chemical binding]; other site 413999002865 Mg2+ binding site [ion binding]; other site 413999002866 G-X-G motif; other site 413999002867 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 60.9,E-value 2.8e-15 413999002868 5 probable transmembrane helices predicted for CBO0614 by TMHMM2.0 at aa 7-25, 29-48, 55-74, 94-111 and 144-166 413999002869 rod shape-determining protein RodA; Region: rodA_shape; TIGR02210 413999002870 10 probable transmembrane helices predicted for CBO0615 by TMHMM2.0 at aa 21-43, 53-75, 87-104, 114-136,149-168, 172-191, 196-215, 283-305, 312-334 and 349-371 413999002871 Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein, score 371.3, E-value 1.1e-108 413999002872 PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 413999002873 Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230 413999002874 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 413999002875 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999002876 S-adenosylmethionine binding site [chemical binding]; other site 413999002877 Pfam match to entry PF02353 CMAS,Cyclopropane-fatty-acyl-phospholipid synthase, score 229.9, E-value 3.8e-66 413999002878 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999002879 dimerization interface [polypeptide binding]; other site 413999002880 putative Zn2+ binding site [ion binding]; other site 413999002881 putative DNA binding site [nucleotide binding]; other site 413999002882 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family, score 63.3, E-value 5.3e-16 413999002883 Predicted helix-turn-helix motif with score 1165.000, SD 3.15 at aa 284-305, sequence KYSLEIAEALKLTPATVSYHMG 413999002884 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999002885 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999002886 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002887 Walker A/P-loop; other site 413999002888 ATP binding site [chemical binding]; other site 413999002889 Q-loop/lid; other site 413999002890 ABC transporter signature motif; other site 413999002891 Walker B; other site 413999002892 D-loop; other site 413999002893 H-loop/switch region; other site 413999002894 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 87.5, E-value 2.9e-23 413999002895 5 probable transmembrane helices predicted for CBO0618 by TMHMM2.0 at aa 13-35, 50-72, 123-145, 150-169 and 237-259 413999002896 Pfam match to entry PF00005 ABC_tran, ABC transporter score 169.9, E-value 4.4e-48 413999002897 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002898 PS00211 ABC transporters family signature. 413999002899 Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845 413999002900 Chloramphenicol acetyltransferase; Region: CAT; smart01059 413999002901 Pfam match to entry PF00302 CAT, Chloramphenicol acetyltransferase, score 53.3, E-value 2.7e-17 413999002902 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999002903 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999002904 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 61.5, E-value 1.9e-15 413999002905 Predicted helix-turn-helix motif with score 1575.000, SD 4.55 at aa 33-54, sequence TSMQDIMDEAKISRGALYSYFK 413999002906 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999002907 Coenzyme A binding pocket [chemical binding]; other site 413999002908 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 73.2, E-value 5.9e-19 413999002909 tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798 413999002910 dimer interface [polypeptide binding]; other site 413999002911 putative tRNA-binding site [nucleotide binding]; other site 413999002912 Pfam match to entry PF01588 tRNA_bind, tRNA binding domain, score 83.6, E-value 4.2e-22 413999002913 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 413999002914 Helix-turn-helix domain; Region: HTH_18; pfam12833 413999002915 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999002916 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 39.3, E-value 8.9e-09 413999002917 PS00041 Bacterial regulatory proteins, araC family signature. 413999002918 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 19.3, E-value 0.0093 413999002919 Predicted helix-turn-helix motif with score 1085.000, SD 2.88 at aa 149-170, sequence IDLKKLAAIEHYNISYYSEWFK 413999002920 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999002921 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 413999002922 non-specific DNA binding site [nucleotide binding]; other site 413999002923 salt bridge; other site 413999002924 sequence-specific DNA binding site [nucleotide binding]; other site 413999002925 Cupin domain; Region: Cupin_2; pfam07883 413999002926 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 63.4, E-value 4.9e-16 413999002927 Predicted helix-turn-helix motif with score 1614.000, SD 4.68 at aa 20-41, sequence LSLGQLAELSNISKVMLSQIEK 413999002928 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215 413999002929 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002930 ABC transporter; Region: ABC_tran; pfam00005 413999002931 Q-loop/lid; other site 413999002932 ABC transporter signature motif; other site 413999002933 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 413999002934 Walker B; other site 413999002935 D-loop; other site 413999002936 H-loop/switch region; other site 413999002937 LytTr DNA-binding domain; Region: LytTR; pfam04397 413999002938 Pfam match to entry PF04397 LytTR, LytTr DNA-binding domain, score 78.0, E-value 2e-20 413999002939 ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555 413999002940 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999002941 Walker A/P-loop; other site 413999002942 ATP binding site [chemical binding]; other site 413999002943 Q-loop/lid; other site 413999002944 ABC transporter signature motif; other site 413999002945 Walker B; other site 413999002946 D-loop; other site 413999002947 H-loop/switch region; other site 413999002948 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.8, E-value 2.9e-55 413999002949 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002950 1 probable transmembrane helix predicted for CBO0628 by TMHMM2.0 at aa 21-40 413999002951 allantoate amidohydrolase; Reviewed; Region: PRK09290 413999002952 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 413999002953 active site 413999002954 metal binding site [ion binding]; metal-binding site 413999002955 dimer interface [polypeptide binding]; other site 413999002956 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 61.4, E-value 2e-15 413999002957 DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533 413999002958 MutS domain III; Region: MutS_III; pfam05192 413999002959 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999002960 Walker A/P-loop; other site 413999002961 ATP binding site [chemical binding]; other site 413999002962 Q-loop/lid; other site 413999002963 ABC transporter signature motif; other site 413999002964 Walker B; other site 413999002965 D-loop; other site 413999002966 H-loop/switch region; other site 413999002967 Pfam match to entry PF00488 MutS_V, MutS domain V,score 4.2, E-value 2.4e-14 413999002968 PS00017 ATP/GTP-binding site motif A (P-loop). 413999002969 Transposon-encoded protein TnpV; Region: TnpV; pfam14198 413999002970 Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467 413999002971 Protein of unknown function (DUF454); Region: DUF454; cl01063 413999002972 Pfam match to entry PF04304 DUF454, Protein of unknown function (DUF454), score 62.5, E-value 9.2e-16 413999002973 3 probable transmembrane helices predicted for CBO0634 by TMHMM2.0 at aa 4-26, 60-82 and 86-105 413999002974 2 probable transmembrane helices predicted for CBO0636 by TMHMM2.0 at aa 2-24 and 50-72 413999002975 Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467 413999002976 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 413999002977 minor groove reading motif; other site 413999002978 PS00294 Prenyl group binding site (CAAX box). 413999002979 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein, score 29.8,E-value 7.1e-08 413999002980 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999002981 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999002982 DNA-binding site [nucleotide binding]; DNA binding site 413999002983 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999002984 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999002985 homodimer interface [polypeptide binding]; other site 413999002986 catalytic residue [active] 413999002987 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 41.9, E-value 1.5e-09 413999002988 PS00043 Bacterial regulatory proteins, gntR family signature. 413999002989 Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022 413999002990 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; cl17869 413999002991 PS00190 Cytochrome c family heme-binding site signature. 413999002992 ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192 413999002993 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 413999002994 ATP binding site [chemical binding]; other site 413999002995 Mg++ binding site [ion binding]; other site 413999002996 motif III; other site 413999002997 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999002998 nucleotide binding region [chemical binding]; other site 413999002999 ATP-binding site [chemical binding]; other site 413999003000 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 285.9, E-value 5.4e-83 413999003001 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003002 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 413999003003 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 125.4, E-value 1.1e-34 413999003004 Uncharacterized family of ferritin-like proteins found in archaea and bacteria; Region: Ferritin_like_AB; cd01045 413999003005 diiron binding motif [ion binding]; other site 413999003006 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999003007 MarR family; Region: MarR_2; pfam12802 413999003008 Pfam match to entry PF01047 MarR, MarR family,score 53.3, E-value 5.7e-13 413999003009 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999003010 Major Facilitator Superfamily; Region: MFS_1; pfam07690 413999003011 putative substrate translocation pore; other site 413999003012 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999003013 14 probable transmembrane helices predicted for CBO0646 by TMHMM2.0 at aa 16-38, 53-75, 87-109, 113-130,143-165, 170-192, 205-223, 228-250, 270-292, 307-329,336-355, 359-378, 399-421 and 446-468 413999003014 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -82.5, E-value 0.00031 413999003015 F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996 413999003016 F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996 413999003017 Transcriptional regulator [Transcription]; Region: LysR; COG0583 413999003018 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 413999003019 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 413999003020 dimerization interface [polypeptide binding]; other site 413999003021 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 77.5, E-value 2.9e-20 413999003022 Predicted helix-turn-helix motif with score 1531.000, SD 4.40 at aa 18-39, sequence KSFSKAAKELYMTQPAVSQSIM 413999003023 PS00044 Bacterial regulatory proteins, lysR family signature. 413999003024 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain, score 76.4, E-value 6.3e-20 413999003025 Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820 413999003026 Protein of unknown function (DUF1703); Region: DUF1703; pfam08011 413999003027 PS00284 Serpins signature. 413999003028 Protein of unknown function C-terminus (DUF2399); Region: DUF2399; pfam09664 413999003029 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 413999003030 putative active site [active] 413999003031 Pfam match to entry PF02698 DUF218, Uncharacterized ACR, COG1434, score 24.8, E-value 1.4e-07 413999003032 N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204 413999003033 PLD-like domain; Region: PLDc_2; pfam13091 413999003034 putative homodimer interface [polypeptide binding]; other site 413999003035 putative active site [active] 413999003036 catalytic site [active] 413999003037 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061 413999003038 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999003039 ATP binding site [chemical binding]; other site 413999003040 putative Mg++ binding site [ion binding]; other site 413999003041 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999003042 nucleotide binding region [chemical binding]; other site 413999003043 ATP-binding site [chemical binding]; other site 413999003044 Domain of unknown function (DUF3427); Region: DUF3427; pfam11907 413999003045 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 61.8, E-value 1.6e-15 413999003046 The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425 413999003047 active site 413999003048 8-oxo-dGMP binding site [chemical binding]; other site 413999003049 nudix motif; other site 413999003050 metal binding site [ion binding]; metal-binding site 413999003051 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 78.2, E-value 1.8e-20 413999003052 PS00893 mutT domain signature. 413999003053 transcriptional antiterminator BglG; Provisional; Region: PRK09772 413999003054 CAT RNA binding domain; Region: CAT_RBD; smart01061 413999003055 PRD domain; Region: PRD; pfam00874 413999003056 PRD domain; Region: PRD; pfam00874 413999003057 Pfam match to entry PF03123 CAT_RBD, CAT RNA binding domain, score 85.7, E-value 9.9e-23 413999003058 Pfam match to entry PF00874 PRD, PRD domain, score 120.3, E-value 3.7e-33 413999003059 Pfam match to entry PF00874 PRD, PRD domain, score 83.8, E-value 3.7e-22 413999003060 PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995 413999003061 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999003062 active site turn [active] 413999003063 phosphorylation site [posttranslational modification] 413999003064 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999003065 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 413999003066 HPr interaction site; other site 413999003067 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999003068 active site 413999003069 phosphorylation site [posttranslational modification] 413999003070 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 60.9, E-value 2.9e-15 413999003071 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 134.4, E-value 2.1e-37 413999003072 9 probable transmembrane helices predicted for CBO0655 by TMHMM2.0 at aa 117-139, 146-168, 202-224,244-266, 281-303, 324-346, 356-378, 391-413 and 428-450 413999003073 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 174.5, E-value 1.9e-49 413999003074 Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613 413999003075 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 413999003076 active site 413999003077 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 413999003078 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region, score 68.3, E-value 1.7e-17 413999003079 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region, score 14.4, E-value 0.03 413999003080 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 413999003081 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 413999003082 ligand binding site [chemical binding]; other site 413999003083 flexible hinge region; other site 413999003084 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 413999003085 putative switch regulator; other site 413999003086 non-specific DNA interactions [nucleotide binding]; other site 413999003087 DNA binding site [nucleotide binding] 413999003088 sequence specific DNA binding site [nucleotide binding]; other site 413999003089 putative cAMP binding site [chemical binding]; other site 413999003090 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain, score 92.3, E-value 1e-24 413999003091 Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family, score 39.1, E-value 1.1e-08 413999003092 Predicted helix-turn-helix motif with score 2015.000, SD 6.05 at aa 186-207, sequence INREEMANYVGVTRETISRKLS 413999003093 Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426 413999003094 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999003095 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 413999003096 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 64.1, E-value 3.2e-16 413999003097 Pfam match to entry PF00258 flavodoxin, Flavodoxin,score 40.8, E-value 3.3e-09 413999003098 Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405 413999003099 iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652 413999003100 Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814 413999003101 Pfam match to entry PF04405 ScdA_N, Domain of Unknown function (DUF542), score 69.1, E-value 9.6e-18 413999003102 Pfam match to entry PF03794 HHE, Domain of Unknown function, score 25.6, E-value 0.00012 413999003103 Pfam match to entry PF03794 HHE, Domain of Unknown function, score 29.1, E-value 1.1e-05 413999003104 Family of unknown function (DUF438); Region: DUF438; pfam04282 413999003105 Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814 413999003106 Pfam match to entry PF04282 DUF438, Family of unknown function (DUF438), score 31.4, E-value 3e-08 413999003107 3 probable transmembrane helices predicted for CBO0661 by TMHMM2.0 at aa 10-32, 44-66 and 86-108 413999003108 PS00012 Phosphopantetheine attachment site. 413999003109 Na+/glutamate symporter [Amino acid transport and metabolism]; Region: GltS; COG0786 413999003110 Pfam match to entry PF03616 Glt_symporter,Sodium/glutamate symporter, score 502.0, E-value 4.7e-148 413999003111 11 probable transmembrane helices predicted for CBO0662 by TMHMM2.0 at aa 5-22, 34-56, 71-88, 95-117,127-149, 156-178, 212-234, 236-258, 273-295, 302-324 and 368-390 413999003112 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999003113 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 78.0, E-value 2e-20 413999003114 PS00136 Serine proteases, subtilase,aspartic acid active site. 413999003115 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574 413999003116 TM-ABC transporter signature motif; other site 413999003117 Pfam match to entry PF02653 BPD_transp_2,Branched-chain amino acid transport system / permease component, score 72.4, E-value 1e-18 413999003118 8 probable transmembrane helices predicted for CBO0668 by TMHMM2.0 at aa 10-27, 40-62, 91-113, 120-139,159-181, 202-224, 234-253 and 265-287 413999003119 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101 413999003120 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999003121 Walker A/P-loop; other site 413999003122 ATP binding site [chemical binding]; other site 413999003123 Q-loop/lid; other site 413999003124 ABC transporter signature motif; other site 413999003125 Walker B; other site 413999003126 D-loop; other site 413999003127 H-loop/switch region; other site 413999003128 Pfam match to entry PF00005 ABC_tran, ABC transporter score 182.8, E-value 6e-52 413999003129 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003130 PS00211 ABC transporters family signature. 413999003131 Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325 413999003132 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 413999003133 zinc binding site [ion binding]; other site 413999003134 putative ligand binding site [chemical binding]; other site 413999003135 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999003136 Pfam match to entry PF04392 DUF534, Protein of unknown function (DUF534), score 275.5, E-value 7.4e-80 413999003137 1 probable transmembrane helix predicted for CBO0673 by TMHMM2.0 at aa 55-72 413999003138 RNA polymerase factor sigma-70; Validated; Region: PRK06811 413999003139 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999003140 Predicted helix-turn-helix motif with score 1240.000, SD 3.41 at aa 146-167, sequence EDMKSICKKFNLSKGAIYNRLW 413999003141 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 24.3, E-value 0.00031 413999003142 tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042 413999003143 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 413999003144 FMN binding site [chemical binding]; other site 413999003145 active site 413999003146 catalytic residues [active] 413999003147 substrate binding site [chemical binding]; other site 413999003148 Pfam match to entry PF01207 Dus, Dihydrouridine synthase (Dus), score 37.5, E-value 1.1e-08 413999003149 PS01136 Uncharacterized protein family UPF0034 signature. 413999003150 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 413999003151 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 413999003152 Pfam match to entry PF03449 GreA_GreB_N,Prokaryotic transcription elongation factor, GreA/GreB,N-terminal domain, score 59.0, E-value 1.1e-14 413999003153 Pfam match to entry PF01272 GreA_GreB, Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain, score 27.1, E-value 5.5e-06 413999003154 Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286 413999003155 HsdM N-terminal domain; Region: HsdM_N; pfam12161 413999003156 Methyltransferase domain; Region: Methyltransf_26; pfam13659 413999003157 Pfam match to entry PF02506 Methylase_M, Type I restriction modification system, M protein, score -51.0,E-value 8.3e-06 413999003158 PS00092 N-6 Adenine-specific DNA methylases signature. 413999003159 Pfam match to entry PF02384 N6_Mtase, N-6 DNA Methylase, score 85.2, E-value 1.4e-22 413999003160 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 413999003161 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 413999003162 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 413999003163 Pfam match to entry PF01420 Methylase_S, Type I restriction modification DNA specificity domain, score 81.0, E-value 2.5e-21 413999003164 Pfam match to entry PF01420 Methylase_S, Type I restriction modification DNA specificity domain, score 39.3, E-value 9.1e-09 413999003165 Domain of unknown function (DUF4351); Region: DUF4351; pfam14261 413999003166 Domain of unknown function (DUF4145); Region: DUF4145; pfam13643 413999003167 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096 413999003168 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313 413999003169 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999003170 ATP binding site [chemical binding]; other site 413999003171 putative Mg++ binding site [ion binding]; other site 413999003172 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351 413999003173 nucleotide binding region [chemical binding]; other site 413999003174 ATP-binding site [chemical binding]; other site 413999003175 Pfam match to entry PF04313 HSDR_N, Type I restriction enzyme R protein N terminus (HSDR_N), score 78.8, E-value 1.1e-20 413999003176 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003177 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 10.5, E-value 0.0023 413999003178 ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073 413999003179 Part of AAA domain; Region: AAA_19; pfam13245 413999003180 Family description; Region: UvrD_C_2; pfam13538 413999003181 Hemimethylated DNA-binding protein YccV like; Region: YccV-like; cl01548 413999003182 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 482.9, E-value 2.7e-142 413999003183 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003184 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999003185 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999003186 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 17.2, E-value 0.028 413999003187 Predicted helix-turn-helix motif with score 1531.000, SD 4.40 at aa 184-205, sequence LTIRSLAELHGVNENRLFYVFS 413999003188 PS00041 Bacterial regulatory proteins, araC family signature. 413999003189 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 47.0, E-value 4.3e-11 413999003190 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999003191 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 413999003192 intersubunit interface [polypeptide binding]; other site 413999003193 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999003194 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 117.2, E-value 3.2e-32 413999003195 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 413999003196 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999003197 ABC-ATPase subunit interface; other site 413999003198 dimer interface [polypeptide binding]; other site 413999003199 putative PBP binding regions; other site 413999003200 10 probable transmembrane helices predicted for CBO0687 by TMHMM2.0 at aa 21-40, 72-94, 107-126, 130-152,164-186, 212-234, 241-263, 267-286, 293-312 and 322-339 413999003201 Pfam match to entry PF01032 FecCD, FecCD transport family, score 369.4, E-value 4e-108 413999003202 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 413999003203 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999003204 ABC-ATPase subunit interface; other site 413999003205 dimer interface [polypeptide binding]; other site 413999003206 putative PBP binding regions; other site 413999003207 9 probable transmembrane helices predicted for CBO0688 by TMHMM2.0 at aa 21-43, 69-91, 104-126, 130-152,164-183, 203-225, 256-278, 288-310 and 323-342 413999003208 Pfam match to entry PF01032 FecCD, FecCD transport family, score 436.6, E-value 2.2e-128 413999003209 PS00215 Mitochondrial energy transfer proteins signature. 413999003210 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 413999003211 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999003212 Walker A/P-loop; other site 413999003213 ATP binding site [chemical binding]; other site 413999003214 Q-loop/lid; other site 413999003215 ABC transporter signature motif; other site 413999003216 Walker B; other site 413999003217 D-loop; other site 413999003218 H-loop/switch region; other site 413999003219 Pfam match to entry PF00005 ABC_tran, ABC transporter score 187.5, E-value 2.2e-53 413999003220 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003221 PS00211 ABC transporters family signature. 413999003222 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999003223 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 413999003224 Pfam match to entry PF00142 fer4_NifH, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family, score 412.3, E-value 4.6e-121 413999003225 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003226 PS00746 NifH/frxC family signature 1. 413999003227 PS00692 NifH/frxC family signature 2. 413999003228 The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia. This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775 413999003229 Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148 413999003230 Pfam match to entry PF00148 oxidored_nitro,Nitrogenase component 1 type Oxidoreductase, score -107.5,E-value 6e-05 413999003231 Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148 413999003232 The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia. This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cd00316 413999003233 Pfam match to entry PF00148 oxidored_nitro,Nitrogenase component 1 type Oxidoreductase, score -40.0,E-value 1.5e-07 413999003234 Cache domain; Region: Cache_1; pfam02743 413999003235 HAMP domain; Region: HAMP; pfam00672 413999003236 dimerization interface [polypeptide binding]; other site 413999003237 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999003238 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999003239 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999003240 dimer interface [polypeptide binding]; other site 413999003241 putative CheW interface [polypeptide binding]; other site 413999003242 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999003243 2 probable transmembrane helices predicted for CBO0693 by TMHMM2.0 at aa 10-32 and 288-310 413999003244 Pfam match to entry PF02743 Cache, Cache domain,score 16.4, E-value 0.00026 413999003245 Pfam match to entry PF00672 HAMP, HAMP domain,score 49.2, E-value 9.3e-12 413999003246 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 139.8, E-value 5.3e-39 413999003247 1 probable transmembrane helix predicted for CBO0694 by TMHMM2.0 at aa 10-32 413999003248 Domain of unknown function (DUF4317); Region: DUF4317; pfam14199 413999003249 Domain of unknown function (DUF4317); Region: DUF4317; pfam14199 413999003250 glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389 413999003251 Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893 413999003252 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 413999003253 Pfam match to entry PF01571 GCV_T, Glycine cleavage T-protein (aminomethyl transferase), score 465.1, E-value 5.9e-137 413999003254 glycine cleavage system protein H; Provisional; Region: PRK13380 413999003255 Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848 413999003256 lipoyl attachment site [posttranslational modification]; other site 413999003257 Pfam match to entry PF01597 GCV_H, Glycine cleavage H-protein, score 197.8, E-value 1.7e-56 413999003258 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403 413999003259 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 413999003260 tetramer interface [polypeptide binding]; other site 413999003261 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003262 catalytic residue [active] 413999003263 Pfam match to entry PF02347 GDC-P, Glycine cleavage system P-protein, score 577.9, E-value 6.7e-171 413999003264 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 413999003265 tetramer interface [polypeptide binding]; other site 413999003266 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003267 catalytic residue [active] 413999003268 Pfam match to entry PF02347 GDC-P, Glycine cleavage system P-protein, score -284.1, E-value 0.00058 413999003269 dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350 413999003270 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999003271 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 413999003272 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 272.7, E-value 5e-79 413999003273 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 413999003274 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain,score 176.2, E-value 5.5e-50 413999003275 Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095 413999003276 lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545 413999003277 Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437 413999003278 Pfam match to entry PF03099 BPL_LipA_LipB,Biotin/lipoate A/B protein ligase, score 127.8,E-value 2.1e-35 413999003279 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 413999003280 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999003281 GyrI-like small molecule binding domain; Region: GyrI-like; cl01368 413999003282 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 48.0, E-value 2.1e-11 413999003283 Predicted helix-turn-helix motif with score 1422.000, SD 4.03 at aa 23-44, sequence ISIEDVANYCNFSKYYFSRMFK 413999003284 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 19.7, E-value 0.0073 413999003285 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003286 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185 413999003287 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 413999003288 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 413999003289 DNA binding residues [nucleotide binding] 413999003290 Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592 413999003291 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999003292 DNA binding residues [nucleotide binding] 413999003293 dimer interface [polypeptide binding]; other site 413999003294 Predicted helix-turn-helix motif with score 1712.000, SD 5.02 at aa 5-26, sequence YKTAEVAKIVGVHPNTVRLYEK 413999003295 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 29.2, E-value 1e-05 413999003296 Predicted helix-turn-helix motif with score 1712.000, SD 5.02 at aa 127-26, sequence KLKLVPKVNRLPNGYRVFTNYHIEQFKLARTAFKVEVLQNGLRKKIINVVKLSAKGE FQEAINCTNDYINQIKQERKNAEEAIELSKKLLLEIDAKDNYIFF 413999003297 Predicted helix-turn-helix motif with score 1396.000, SD 3.94 at aa 127-148, sequence FTRKQTSDYLQVTMDTLRNWEM 413999003298 ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121 413999003299 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999003300 Walker A/P-loop; other site 413999003301 ATP binding site [chemical binding]; other site 413999003302 Q-loop/lid; other site 413999003303 ABC transporter signature motif; other site 413999003304 Walker B; other site 413999003305 D-loop; other site 413999003306 H-loop/switch region; other site 413999003307 Pfam match to entry PF00005 ABC_tran, ABC transporter score 132.3, E-value 9.1e-37 413999003308 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003309 PS00211 ABC transporters family signature. 413999003310 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 413999003311 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 413999003312 6 probable transmembrane helices predicted for CBO0710 by TMHMM2.0 at aa 23-42, 57-79, 100-122, 137-159,166-188 and 223-245 413999003313 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999003314 Walker A/P-loop; other site 413999003315 ATP binding site [chemical binding]; other site 413999003316 Q-loop/lid; other site 413999003317 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 413999003318 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 413999003319 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999003320 Walker A/P-loop; other site 413999003321 ATP binding site [chemical binding]; other site 413999003322 Q-loop/lid; other site 413999003323 ABC transporter signature motif; other site 413999003324 Walker B; other site 413999003325 D-loop; other site 413999003326 H-loop/switch region; other site 413999003327 Pfam match to entry PF00005 ABC_tran, ABC transporter score 38.4, E-value 5.2e-09 413999003328 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003329 Pfam match to entry PF00005 ABC_tran, ABC transporter score 80.5, E-value 3.5e-21 413999003330 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003331 PS00211 ABC transporters family signature. 413999003332 UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580 413999003333 Part of AAA domain; Region: AAA_19; pfam13245 413999003334 Family description; Region: UvrD_C_2; pfam13538 413999003335 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 7.1, E-value 0.043 413999003336 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003337 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 16.6, E-value 0.0001 413999003338 Phage protein Gp37/Gp68; Region: Gp37_Gp68; cl15384 413999003339 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999003340 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999003341 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708 413999003342 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999003343 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 28.9, E-value 1.3e-05 413999003344 PS00041 Bacterial regulatory proteins, araC family signature. 413999003345 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 27.1, E-value 4.4e-05 413999003346 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 413999003347 EamA-like transporter family; Region: EamA; pfam00892 413999003348 EamA-like transporter family; Region: EamA; pfam00892 413999003349 10 probable transmembrane helices predicted for CBO0715 by TMHMM2.0 at aa 5-27, 32-49, 62-84, 89-111,116-138, 148-165, 178-195, 205-227, 239-258 and 262-284 413999003350 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 81.5, E-value 1.8e-21 413999003351 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 52.9, E-value 7.3e-13 413999003352 TfoX C-terminal domain; Region: TfoX_C; pfam04994 413999003353 Pfam match to entry PF04994 TfoX_C, TfoX C-terminal domain, score 40.9, E-value 2.9e-09 413999003354 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 413999003355 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999003356 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 39.7, E-value 6.9e-09 413999003357 3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332 413999003358 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 413999003359 active site 413999003360 1 probable transmembrane helix predicted for CBO0718 by TMHMM2.0 at aa 313-330 413999003361 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999003362 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999003363 dimer interface [polypeptide binding]; other site 413999003364 putative CheW interface [polypeptide binding]; other site 413999003365 5 probable transmembrane helices predicted for CBO0719 by TMHMM2.0 at aa 13-32, 37-56, 76-98, 108-125 and 137-159 413999003366 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 82.6, E-value 8.3e-22 413999003367 Mor transcription activator family; Region: Mor; cl02360 413999003368 Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 69-90, sequence ASVKTLAEEYFLTEGSIRRIIR 413999003369 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 413999003370 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999003371 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999003372 ABC transporter; Region: ABC_tran_2; pfam12848 413999003373 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999003374 Pfam match to entry PF00005 ABC_tran, ABC transporter score 125.4, E-value 1.1e-34 413999003375 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003376 PS00211 ABC transporters family signature. 413999003377 Pfam match to entry PF00005 ABC_tran, ABC transporter score 114.6, E-value 2e-31 413999003378 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003379 PS00211 ABC transporters family signature. 413999003380 WYL domain; Region: WYL; pfam13280 413999003381 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 413999003382 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_3; cd03140 413999003383 conserved cys residue [active] 413999003384 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family, score 31.1, E-value 8.8e-07 413999003385 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 413999003386 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 413999003387 dimer interface [polypeptide binding]; other site 413999003388 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003389 catalytic residue [active] 413999003390 Pfam match to entry PF00291 PALP,Pyridoxal-phosphate dependent enzyme, score 384.0, E-value 1.6e-112 413999003391 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 413999003392 S-ribosylhomocysteinase; Provisional; Region: PRK02260 413999003393 Pfam match to entry PF02664 LuxS, LuxS protein,score 208.4, E-value 1.1e-59 413999003394 cystathionine beta-lyase; Provisional; Region: PRK07671 413999003395 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 413999003396 homodimer interface [polypeptide binding]; other site 413999003397 substrate-cofactor binding pocket; other site 413999003398 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003399 catalytic residue [active] 413999003400 Pfam match to entry PF01053 Cys_Met_Meta_PP,Cys/Met metabolism PLP-dependent enzyme, score 739.8,E-value 1.2e-219 413999003401 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 413999003402 Methyltransferase domain; Region: Methyltransf_31; pfam13847 413999003403 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999003404 S-adenosylmethionine binding site [chemical binding]; other site 413999003405 Glyco_18 domain; Region: Glyco_18; smart00636 413999003406 The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548 413999003407 active site 413999003408 Chitinase C; Region: ChiC; pfam06483 413999003409 Pfam match to entry PF00704 Glyco_hydro_18,Glycosyl hydrolases family 18, score 373.8, E-value 1.9e-109 413999003410 PS01095 Chitinases family 18 active site. 413999003411 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 413999003412 metal-binding site [ion binding] 413999003413 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 51.8, E-value 1.6e-12 413999003414 PS00050 Ribosomal protein L23 signature. 413999003415 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 413999003416 Domain of unknown function (DUF4071); Region: DUF4071; pfam13281 413999003417 Cupin superfamily (DUF985); Region: Cupin_5; pfam06172 413999003418 Pfam match to entry PF06172 DUF985, Protein of unknown function (DUF985), score 259.5, E-value 4.6e-75 413999003419 Domain of unknown function (DUF955); Region: DUF955; pfam06114 413999003420 Predicted helix-turn-helix motif with score 1509.000, SD 4.33 at aa 159-180, sequence TSIKEVATYFNVSESAVLKRLT 413999003421 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999003422 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999003423 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999003424 non-specific DNA binding site [nucleotide binding]; other site 413999003425 salt bridge; other site 413999003426 sequence-specific DNA binding site [nucleotide binding]; other site 413999003427 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 58.9, E-value 1.1e-14 413999003428 Predicted helix-turn-helix motif with score 1566.000, SD 4.52 at aa 16-37, sequence LSQRQLAELSHISNTEISRIES 413999003429 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999003430 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999003431 non-specific DNA binding site [nucleotide binding]; other site 413999003432 salt bridge; other site 413999003433 sequence-specific DNA binding site [nucleotide binding]; other site 413999003434 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 44.7, E-value 2.1e-10 413999003435 Predicted helix-turn-helix motif with score 2294.000, SD 7.00 at aa 17-38, sequence WSQNKFAKKAGVSNATISRWTN 413999003436 Replication initiation and membrane attachment; Region: DnaB_2; pfam07261 413999003437 Pfam match to entry PF04271 DnaD, DnaD-like domain,score 41.6, E-value 1.9e-09 413999003438 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 413999003439 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999003440 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257 413999003441 DNA binding residues [nucleotide binding] 413999003442 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 13.4, E-value 0.0068 413999003443 S23 ribosomal protein; Region: Ribosomal_S23p; cl05287 413999003444 four helix bundle protein; Region: TIGR02436 413999003445 1 probable transmembrane helix predicted for CBO0738 by TMHMM2.0 at aa 10-28 413999003446 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 413999003447 active site 413999003448 metal binding site [ion binding]; metal-binding site 413999003449 Pfam match to entry PF00149 Metallophos,Calcineurin-like phosphoesterase, score 25.8, E-value 0.0001 413999003450 Protein of unknown function (DUF1659); Region: DUF1659; pfam07872 413999003451 Protein of unknown function (DUF2922); Region: DUF2922; pfam11148 413999003452 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 413999003453 amidase catalytic site [active] 413999003454 Zn binding residues [ion binding]; other site 413999003455 substrate binding site [chemical binding]; other site 413999003456 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 413999003457 Pfam match to entry PF01510 Amidase_2,N-acetylmuramoyl-L-alanine amidase, score 74.5, E-value 2.3e-19 413999003458 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain, score 49.7, E-value 6.6e-12 413999003459 Protein of unknown function (DUF2762); Region: DUF2762; pfam10960 413999003460 1 probable transmembrane helix predicted for CBO0746 by TMHMM2.0 at aa 13-30 413999003461 Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296 413999003462 putative active site [active] 413999003463 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999003464 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999003465 Domain of Unknown Function (DUF1259); Region: DUF1529; pfam07485 413999003466 Domain of Unknown Function (DUF1259); Region: DUF1529; pfam07485 413999003467 Pfam match to entry PF01476 LysM, LysM domain,score 32.8, E-value 8.4e-07 413999003468 Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394 413999003469 Low molecular weight phosphatase family; Region: LMWPc; cl00105 413999003470 active site 413999003471 Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase, score 48.5,E-value 1.6e-11 413999003472 Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719 413999003473 1 probable transmembrane helix predicted for CBO0752 by TMHMM2.0 at aa 54-76 413999003474 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999003475 dimerization interface [polypeptide binding]; other site 413999003476 putative DNA binding site [nucleotide binding]; other site 413999003477 putative Zn2+ binding site [ion binding]; other site 413999003478 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family, score 90.5, E-value 3.5e-24 413999003479 PS00846 Bacterial regulatory proteins, arsR family signature. 413999003480 Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953 413999003481 arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291 413999003482 ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035 413999003483 P loop; other site 413999003484 Nucleotide binding site [chemical binding]; other site 413999003485 DTAP/Switch II; other site 413999003486 Switch I; other site 413999003487 ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035 413999003488 P loop; other site 413999003489 Nucleotide binding site [chemical binding]; other site 413999003490 DTAP/Switch II; other site 413999003491 Switch I; other site 413999003492 Pfam match to entry PF02374 ArsA_ATPase,Anion-transporting ATPase, score 317.6, E-value 1.5e-92 413999003493 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003494 Pfam match to entry PF02374 ArsA_ATPase,Anion-transporting ATPase, score 45.6, E-value 1.6e-15 413999003495 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003496 Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798 413999003497 arsenical-resistance protein; Region: acr3; TIGR00832 413999003498 10 probable transmembrane helices predicted for CBO0756 by TMHMM2.0 at aa 20-37, 57-79, 86-105, 125-147,159-181, 185-207, 232-254, 259-281, 294-316 and 320-342 413999003499 Pfam match to entry PF01758 SBF, Sodium Bile acid symporter family, score 160.6, E-value 2.9e-45 413999003500 Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040 413999003501 catalytic core [active] 413999003502 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999003503 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999003504 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 24.7, E-value 1.6e-06 413999003505 PS01081 Bacterial regulatory proteins, tetR family signature. 413999003506 2 probable transmembrane helices predicted for CBO0761 by TMHMM2.0 at aa 33-52 and 56-78 413999003507 Cysteine-rich KTR; Region: Cys_rich_KTR; pfam14205 413999003508 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999003509 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999003510 non-specific DNA binding site [nucleotide binding]; other site 413999003511 salt bridge; other site 413999003512 sequence-specific DNA binding site [nucleotide binding]; other site 413999003513 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 69.3, E-value 8.7e-18 413999003514 Predicted helix-turn-helix motif with score 2365.000, SD 7.24 at aa 15-36, sequence LSQQQLAEKVGVTRQTISMIES 413999003515 2 probable transmembrane helices predicted for CBO0764 by TMHMM2.0 at aa 39-56 and 110-132 413999003516 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999003517 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999003518 Walker A/P-loop; other site 413999003519 ATP binding site [chemical binding]; other site 413999003520 Q-loop/lid; other site 413999003521 ABC transporter signature motif; other site 413999003522 Walker B; other site 413999003523 D-loop; other site 413999003524 H-loop/switch region; other site 413999003525 Pfam match to entry PF00005 ABC_tran, ABC transporter score 163.0, E-value 5.4e-46 413999003526 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003527 PS00211 ABC transporters family signature. 413999003528 6 probable transmembrane helices predicted for CBO0766 by TMHMM2.0 at aa 20-37, 137-159, 186-208,257-279, 286-308 and 351-373 413999003529 6 probable transmembrane helices predicted for CBO0767 by TMHMM2.0 at aa 20-37, 136-158, 185-207,256-278, 285-304 and 350-372 413999003530 Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; cl17818 413999003531 Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351 413999003532 Thymidylate synthase; Region: Thymidylat_synt; pfam00303 413999003533 dimerization interface [polypeptide binding]; other site 413999003534 active site 413999003535 Pfam match to entry PF00303 thymidylat_synt,Thymidylate synthase, score -109.4, E-value 3.3e-05 413999003536 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999003537 S-adenosylmethionine binding site [chemical binding]; other site 413999003538 Pfam match to entry PF01209 Ubie_methyltran,ubiE/COQ5 methyltransferase, score -98.4, E-value 3.7e-06 413999003539 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 413999003540 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 413999003541 dimer interface [polypeptide binding]; other site 413999003542 substrate binding site [chemical binding]; other site 413999003543 ATP binding site [chemical binding]; other site 413999003544 Putative small multi-drug export protein; Region: Sm_multidrug_ex; pfam06695 413999003545 4 probable transmembrane helices predicted for CBO0773 by TMHMM2.0 at aa 5-22, 32-54, 94-116 and 131-153 413999003546 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999003547 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999003548 Walker A/P-loop; other site 413999003549 ATP binding site [chemical binding]; other site 413999003550 Q-loop/lid; other site 413999003551 ABC transporter signature motif; other site 413999003552 Walker B; other site 413999003553 D-loop; other site 413999003554 H-loop/switch region; other site 413999003555 Pfam match to entry PF00005 ABC_tran, ABC transporter score 183.9, E-value 2.8e-52 413999003556 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003557 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999003558 PS00211 ABC transporters family signature. 413999003559 13 probable transmembrane helices predicted for CBO0775 by TMHMM2.0 at aa 62-84, 88-110, 135-157, 167-189,201-220, 235-257, 264-286, 348-370, 383-405, 434-456,463-480, 495-514 and 521-543 413999003560 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999003561 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999003562 active site 413999003563 phosphorylation site [posttranslational modification] 413999003564 intermolecular recognition site; other site 413999003565 dimerization interface [polypeptide binding]; other site 413999003566 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999003567 DNA binding site [nucleotide binding] 413999003568 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 112.2, E-value 1e-30 413999003569 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 80.8, E-value 2.9e-21 413999003570 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999003571 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999003572 Walker A/P-loop; other site 413999003573 ATP binding site [chemical binding]; other site 413999003574 Q-loop/lid; other site 413999003575 ABC transporter signature motif; other site 413999003576 Walker B; other site 413999003577 D-loop; other site 413999003578 H-loop/switch region; other site 413999003579 Pfam match to entry PF00005 ABC_tran, ABC transporter score 164.2, E-value 2.3e-46 413999003580 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003581 PS00211 ABC transporters family signature. 413999003582 ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866 413999003583 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999003584 6 probable transmembrane helices predicted for CBO0778 by TMHMM2.0 at aa 21-38, 78-97, 125-147, 162-184,191-213 and 235-257 413999003585 Helix-turn-helix domain; Region: HTH_18; pfam12833 413999003586 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999003587 Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871 413999003588 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 35.5, E-value 1.3e-07 413999003589 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 29.4, E-value 8.9e-06 413999003590 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999003591 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999003592 dimer interface [polypeptide binding]; other site 413999003593 phosphorylation site [posttranslational modification] 413999003594 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999003595 ATP binding site [chemical binding]; other site 413999003596 Mg2+ binding site [ion binding]; other site 413999003597 G-X-G motif; other site 413999003598 1 probable transmembrane helix predicted for CBO0780 by TMHMM2.0 at aa 2-21 413999003599 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 65.7, E-value 1.1e-16 413999003600 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 67.6,E-value 2.8e-17 413999003601 Protein of unknown function (DUF4003); Region: DUF4003; pfam13170 413999003602 PS00099 Thiolases active site. 413999003603 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999003604 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999003605 Walker A/P-loop; other site 413999003606 ATP binding site [chemical binding]; other site 413999003607 Q-loop/lid; other site 413999003608 ABC transporter signature motif; other site 413999003609 Walker B; other site 413999003610 D-loop; other site 413999003611 H-loop/switch region; other site 413999003612 Pfam match to entry PF00005 ABC_tran, ABC transporter score 211.4, E-value 1.4e-60 413999003613 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003614 PS00211 ABC transporters family signature. 413999003615 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 413999003616 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999003617 FtsX-like permease family; Region: FtsX; pfam02687 413999003618 FtsX-like permease family; Region: FtsX; pfam02687 413999003619 8 probable transmembrane helices predicted for CBO0784 by TMHMM2.0 at aa 20-42, 293-315, 345-367,389-411, 462-484, 764-786, 813-835 and 850-872 413999003620 Pfam match to entry PF02687 FtsX, Predicted permease, score 99.3, E-value 7.7e-27 413999003621 Pfam match to entry PF02687 FtsX, Predicted permease, score 93.2, E-value 5.5e-25 413999003622 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999003623 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999003624 active site 413999003625 phosphorylation site [posttranslational modification] 413999003626 intermolecular recognition site; other site 413999003627 dimerization interface [polypeptide binding]; other site 413999003628 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999003629 DNA binding site [nucleotide binding] 413999003630 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 113.3, E-value 4.8e-31 413999003631 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 91.2, E-value 2.2e-24 413999003632 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999003633 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999003634 dimer interface [polypeptide binding]; other site 413999003635 phosphorylation site [posttranslational modification] 413999003636 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999003637 ATP binding site [chemical binding]; other site 413999003638 Mg2+ binding site [ion binding]; other site 413999003639 G-X-G motif; other site 413999003640 2 probable transmembrane helices predicted for CBO0787 by TMHMM2.0 at aa 13-32 and 112-134 413999003641 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 53.9, E-value 3.8e-13 413999003642 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 107.7, E-value 2.3e-29 413999003643 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 413999003644 small acid-soluble spore protein, H-type; Region: SASP_H; TIGR02861 413999003645 7 probable transmembrane helices predicted for CBO0790 by TMHMM2.0 at aa 15-37, 50-72, 77-99, 112-134,149-171, 191-213 and 233-255 413999003646 dihydrodipicolinate reductase; Provisional; Region: PRK00048 413999003647 Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113 413999003648 Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173 413999003649 Pfam match to entry PF01113 DapB_N,Dihydrodipicolinate reductase, N-terminus, score 111.8,E-value 1.4e-30 413999003650 Pfam match to entry PF05173 DapB_C,Dihydrodipicolinate reductase, C-terminus, score 169.5,E-value 5.7e-48 413999003651 Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897 413999003652 Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448 413999003653 active site residue [active] 413999003654 Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449 413999003655 active site residue [active] 413999003656 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 50.8, E-value 3.1e-12 413999003657 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 55.5, E-value 1.2e-13 413999003658 Flagellin and related hook-associated proteins [Cell motility and secretion]; Region: FlgL; COG1344 413999003659 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999003660 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 17.7, E-value 8.9e-06 413999003661 Predicted helix-turn-helix motif with score 1032.000, SD 2.70 at aa 23-44, sequence VSFGVLAQECNINKQDIQKCFV 413999003662 Clostridium enterotoxin; Region: Clenterotox; pfam03505 413999003663 Clostridium enterotoxin; Region: Clenterotox; pfam03505 413999003664 Pfam match to entry PF03505 Clenterotox,Clostridium enterotoxin, score 473.1, E-value 2.3e-139 413999003665 Pfam match to entry PF03505 Clenterotox,Clostridium enterotoxin, score 24.9, E-value 8.3e-07 413999003666 Clostridium botulinum HA-17 protein; Region: Botulinum_HA-17; pfam05588 413999003667 Pfam match to entry PF05588 botulinum_HA-17,Clostridium botulinum HA-17 protein, score 391.7, E-value 7.4e-115 413999003668 Ricin-type beta-trefoil; Region: RICIN; smart00458 413999003669 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cl15820 413999003670 Ricin-type beta-trefoil; Region: RICIN; smart00458 413999003671 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161 413999003672 putative sugar binding sites [chemical binding]; other site 413999003673 Q-X-W motif; other site 413999003674 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat, score 55.4, E-value 1.3e-13 413999003675 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat, score 15.9, E-value 0.044 413999003676 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat, score 22.4, E-value 0.0011 413999003677 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat, score 2.0, E-value 4.3 413999003678 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat, score 19.8, E-value 0.0067 413999003679 BotR-binding site 413999003680 clostridium toxin-associated regulator BotR; Region: P21_Cbot; TIGR03209 413999003681 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 413999003682 DNA binding residues [nucleotide binding] 413999003683 Predicted helix-turn-helix motif with score 1275.000, SD 3.53 at aa 144-165, sequence IKEIDIAKKLNISRQSVYKNKI 413999003684 BotR-binding site 413999003685 Clostridial neurotoxin zinc protease; Region: Peptidase_M27; pfam01742 413999003686 Clostridium neurotoxin, Translocation domain; Region: Toxin_trans; pfam07952 413999003687 Clostridium neurotoxin, N-terminal receptor binding; Region: Toxin_R_bind_N; pfam07953 413999003688 Nontoxic nonhaemagglutinin C-terminal; Region: NTNH_C; pfam08470 413999003689 Pfam match to entry PF01742 Peptidase_M27,Clostridial neurotoxin zinc protease, score 702.1, E-value 2.7e-208 413999003690 Clostridial neurotoxin zinc protease; Region: Peptidase_M27; pfam01742 413999003691 Clostridium neurotoxin, Translocation domain; Region: Toxin_trans; pfam07952 413999003692 Clostridium neurotoxin, N-terminal receptor binding; Region: Toxin_R_bind_N; pfam07953 413999003693 Clostridium neurotoxin, C-terminal receptor binding; Region: Toxin_R_bind_C; pfam07951 413999003694 Pfam match to entry PF01742 Peptidase_M27,Clostridial neurotoxin zinc protease, score 780.1, E-value 9e-232 413999003695 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999003696 Pfam match to entry PF00665 rve, Integrase core domain, score 17.5, E-value 0.00016 413999003697 Pfam match to entry PF00665 rve, Integrase core domain, score 50.2, E-value 4.8e-12 413999003698 Pfam match to entry PF01527 Transposase_8,Transposase, score 28.5, E-value 8.3e-08 413999003699 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801 413999003700 HTH-like domain; Region: HTH_21; pfam13276 413999003701 Integrase core domain; Region: rve; pfam00665 413999003702 Integrase core domain; Region: rve_3; pfam13683 413999003703 Pfam match to entry PF00665 rve, Integrase core domain, score 170.9, E-value 2.3e-48 413999003704 zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240 413999003705 1 probable transmembrane helix predicted for CBO0811 by TMHMM2.0 at aa 77-94 413999003706 Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228 413999003707 Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309 413999003708 active site 413999003709 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score -4.3, E-value 0.0005 413999003710 Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547 413999003711 Pfam match to entry PF05525 Branch_AA_trans,Branched-chain amino acid transport protein, score 541.5,E-value 6.3e-160 413999003712 12 probable transmembrane helices predicted for CBO0813 by TMHMM2.0 at aa 9-31, 41-63, 76-98, 113-135,148-170, 185-207, 220-242, 274-296, 308-325, 335-357,364-386 and 406-425 413999003713 Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547 413999003714 Pfam match to entry PF05525 Branch_AA_trans,Branched-chain amino acid transport protein, score 517.0,E-value 1.5e-152 413999003715 12 probable transmembrane helices predicted for CBO0814 by TMHMM2.0 at aa 9-31, 41-63, 76-98, 113-135,147-169, 184-206, 218-240, 273-295, 308-330, 340-358,365-387 and 397-419 413999003716 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999003717 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999003718 dimer interface [polypeptide binding]; other site 413999003719 putative CheW interface [polypeptide binding]; other site 413999003720 The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995 413999003721 Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496 413999003722 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, score 198.9, E-value 8.3e-57 413999003723 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 413999003724 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 79.2, E-value 9.1e-21 413999003725 FeoA domain; Region: FeoA; pfam04023 413999003726 Pfam match to entry PF04023 FeoA, FeoA family,score 49.8, E-value 6.4e-12 413999003727 Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249 413999003728 GTP/Mg2+ binding site [chemical binding]; other site 413999003729 G5 box; other site 413999003730 Ferrous iron transport protein B; Region: FeoB_N; pfam02421 413999003731 Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879 413999003732 G1 box; other site 413999003733 G1 box; other site 413999003734 GTP/Mg2+ binding site [chemical binding]; other site 413999003735 Switch I region; other site 413999003736 G2 box; other site 413999003737 G3 box; other site 413999003738 Switch II region; other site 413999003739 G4 box; other site 413999003740 G5 box; other site 413999003741 Pfam match to entry PF02421 FeoB, Ferrous iron transport protein B, score 261.0, E-value 2.9e-77 413999003742 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003743 Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370 413999003744 Nucleoside recognition; Region: Gate; pfam07670 413999003745 Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664 413999003746 Pfam match to entry PF02421 FeoB, Ferrous iron transport protein B, score -51.3, E-value 1.4e-17 413999003747 10 probable transmembrane helices predicted for CBO0818 by TMHMM2.0 at aa 111-130, 150-172, 174-196,222-244, 256-278, 288-310, 350-372, 398-420, 440-462 and 482-504 413999003748 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 413999003749 catalytic core [active] 413999003750 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase, score 127.3, E-value 2.9e-35 413999003751 PS00175 Phosphoglycerate mutase phosphohistidine signature. 413999003752 Uncharacterized vancomycin resistance protein [Defense mechanisms]; Region: COG2720 413999003753 Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229 413999003754 VanW like protein; Region: VanW; pfam04294 413999003755 G5 domain; Region: G5; pfam07501 413999003756 Pfam match to entry PF04294 VanW, VanW like protein, score 244.3, E-value 1.8e-70 413999003757 cobalamin synthase; Reviewed; Region: cobS; PRK00235 413999003758 Pfam match to entry PF02654 CobS,Cobalamin-5-phosphate synthase, score 145.5, E-value 9.9e-41 413999003759 6 probable transmembrane helices predicted for CBO0821 by TMHMM2.0 at aa 34-56, 60-82, 112-134, 138-157,170-192 and 197-219 413999003760 AIR synthase related protein, N-terminal domain; Region: AIRS; pfam00586 413999003761 3 probable transmembrane helices predicted for CBO0823 by TMHMM2.0 at aa 4-23, 30-52 and 57-76 413999003762 Coat F domain; Region: Coat_F; pfam07875 413999003763 Putative NodB-like catalytic domain of uncharacterized proteins found in bacteria; Region: CE4_COG5298; cd10923 413999003764 Uncharacterized protein conserved in bacteria (DUF2334); Region: DUF2334; pfam10096 413999003765 NodB motif; other site 413999003766 putative active site [active] 413999003767 putative catalytic site [active] 413999003768 putative Zn binding site [ion binding]; other site 413999003769 1 probable transmembrane helix predicted for CBO0826 by TMHMM2.0 at aa 7-26 413999003770 6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242 413999003771 active site 413999003772 Pfam match to entry PF01242 PTPS, 6-pyruvoyl tetrahydropterin synthase, score 77.1, E-value 3.8e-20 413999003773 DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739 413999003774 dihydropteroate synthase; Region: DHPS; TIGR01496 413999003775 substrate binding pocket [chemical binding]; other site 413999003776 dimer interface [polypeptide binding]; other site 413999003777 inhibitor binding site; inhibition site 413999003778 Pfam match to entry PF00809 Pterin_bind, Pterin binding enzyme, score 404.4, E-value 1.1e-118 413999003779 PS00793 Dihydropteroate synthase signature 2. 413999003780 Dihydroxyacetone kinase family; Region: Dak1_2; pfam13684 413999003781 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483 413999003782 catalytic center binding site [active] 413999003783 ATP binding site [chemical binding]; other site 413999003784 Pfam match to entry PF01288 HPPK,7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK), score 230.1, E-value 3.4e-66 413999003785 PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 413999003786 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 413999003787 Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471 413999003788 putative dimer interface [polypeptide binding]; other site 413999003789 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family, score 98.1, E-value 1.8e-26 413999003790 Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106 413999003791 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999003792 DNA binding residues [nucleotide binding] 413999003793 dimer interface [polypeptide binding]; other site 413999003794 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999003795 S-adenosylmethionine binding site [chemical binding]; other site 413999003796 Predicted helix-turn-helix motif with score 1630.000, SD 4.74 at aa 9-30, sequence FTTGEFAKKAGVTIRTLRYYDK 413999003797 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 66.1, E-value 7.8e-17 413999003798 PS00552 Bacterial regulatory proteins, merR family signature. 413999003799 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 413999003800 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 413999003801 inhibitor-cofactor binding pocket; inhibition site 413999003802 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003803 catalytic residue [active] 413999003804 Pfam match to entry PF01041 DegT_DnrJ_EryC1,DegT/DnrJ/EryC1/StrS aminotransferase, score 362.3,E-value 5.4e-106 413999003805 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 413999003806 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 413999003807 inhibitor-cofactor binding pocket; inhibition site 413999003808 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003809 catalytic residue [active] 413999003810 Pfam match to entry PF01041 DegT_DnrJ_EryC1,DegT/DnrJ/EryC1/StrS aminotransferase, score 450.2,E-value 1.9e-132 413999003811 Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467 413999003812 RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3 413999003813 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999003814 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999003815 DNA binding residues [nucleotide binding] 413999003816 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 41.0, E-value 2.8e-09 413999003817 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 58.2, E-value 1.8e-14 413999003818 Domain of unknown function (DUF4179); Region: DUF4179; pfam13786 413999003819 1 probable transmembrane helix predicted for CBO0837 by TMHMM2.0 at aa 40-57 413999003820 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 413999003821 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999003822 1 probable transmembrane helix predicted for CBO0839 by TMHMM2.0 at aa 4-26 413999003823 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 413999003824 Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342 413999003825 7 probable transmembrane helices predicted for CBO0841 by TMHMM2.0 at aa 21-38, 58-80, 93-115, 119-141,184-206, 216-238 and 251-273 413999003826 Cadmium resistance transporter; Region: Cad; pfam03596 413999003827 Pfam match to entry PF03596 Cad, Cadmium resistance transporter score 65.6, E-value 1.1e-16 413999003828 Protein of unknown function (DUF523); Region: DUF523; pfam04463 413999003829 Pfam match to entry PF04463 DUF523, Protein of unknown function (DUF523), score 133.8, E-value 3.3e-37 413999003830 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 413999003831 MarR family; Region: MarR_2; cl17246 413999003832 AsnC family; Region: AsnC_trans_reg; pfam01037 413999003833 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family, score 23.0, E-value 2.2e-07 413999003834 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 413999003835 Pfam match to entry PF02567 PhzC-PhzF, Phenazine biosynthesis-like protein, score 85.3, E-value 1.3e-22 413999003836 ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668 413999003837 ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866 413999003838 6 probable transmembrane helices predicted for CBO0845 by TMHMM2.0 at aa 21-43, 87-109, 134-156, 176-198,211-230 and 234-251 413999003839 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999003840 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999003841 Walker A/P-loop; other site 413999003842 ATP binding site [chemical binding]; other site 413999003843 Q-loop/lid; other site 413999003844 ABC transporter signature motif; other site 413999003845 Walker B; other site 413999003846 D-loop; other site 413999003847 H-loop/switch region; other site 413999003848 Pfam match to entry PF00005 ABC_tran, ABC transporter score 143.6, E-value 3.8e-40 413999003849 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003850 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999003851 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999003852 non-specific DNA binding site [nucleotide binding]; other site 413999003853 salt bridge; other site 413999003854 sequence-specific DNA binding site [nucleotide binding]; other site 413999003855 PS00017 ATP/GTP-binding site motif A (P-loop). 413999003856 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 63.3, E-value 5.6e-16 413999003857 Predicted helix-turn-helix motif with score 2141.000, SD 6.48 at aa 19-40, sequence ITQEQLANYIGVSKASVSKWES 413999003858 PS00228 Tubulin-beta mRNA autoregulation signal. 413999003859 TIGR04076 family protein; Region: TIGR04076 413999003860 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 413999003861 Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342 413999003862 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold, score 102.3, E-value 1e-27 413999003863 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 413999003864 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 413999003865 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 31.3, E-value 2.4e-06 413999003866 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 413999003867 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 413999003868 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 413999003869 Pfam match to entry PF00805 Pentapeptide,Pentapeptide repeats (8 copies), score 23.1, E-value 0.00068 413999003870 Pfam match to entry PF00805 Pentapeptide,Pentapeptide repeats (8 copies), score 19.5, E-value 0.0082 413999003871 Pfam match to entry PF00805 Pentapeptide,Pentapeptide repeats (8 copies), score 5.4, E-value 0.77 413999003872 Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525 413999003873 Pfam match to entry PF02525 Flavodoxin_2,Flavodoxin-like fold, score 79.0, E-value 1e-20 413999003874 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999003875 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 413999003876 Pfam match to entry PF03358 FMN_red,NADPH-dependent FMN reductase, score 17.9, E-value 8.5e-08 413999003877 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999003878 dimerization interface [polypeptide binding]; other site 413999003879 putative DNA binding site [nucleotide binding]; other site 413999003880 putative Zn2+ binding site [ion binding]; other site 413999003881 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family, score 35.7, E-value 1.1e-07 413999003882 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 413999003883 Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782 413999003884 DNA binding residues [nucleotide binding] 413999003885 dimer interface [polypeptide binding]; other site 413999003886 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 54.4, E-value 2.6e-13 413999003887 Predicted helix-turn-helix motif with score 1284.000, SD 3.56 at aa 15-36, sequence LRIGQVSKLYGISLDTLRHYDR 413999003888 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999003889 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 413999003890 Coenzyme A binding pocket [chemical binding]; other site 413999003891 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 35.2, E-value 1.6e-07 413999003892 Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229 413999003893 Pfam match to entry PF04229 UPF0157,Uncharacterised protein family (UPF0157), score 162.0,E-value 1.1e-45 413999003894 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999003895 Coenzyme A binding pocket [chemical binding]; other site 413999003896 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 40.1, E-value 5.3e-09 413999003897 Pirin-related protein [General function prediction only]; Region: COG1741 413999003898 Pirin; Region: Pirin; pfam02678 413999003899 Pfam match to entry PF02678 Pirin, Pirin, score 171.9, E-value 1.1e-48 413999003900 Predicted transcriptional regulators [Transcription]; Region: COG1733 413999003901 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 413999003902 Pfam match to entry PF01638 DUF24, Transcriptional regulator, score 144.5, E-value 1.9e-40 413999003903 Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137 413999003904 dimer interface [polypeptide binding]; other site 413999003905 FMN binding site [chemical binding]; other site 413999003906 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 126.5, E-value 5.1e-35 413999003907 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 413999003908 PS00430 TonB-dependent receptor proteins signature 1. 413999003909 PS00120 Lipases, serine active site. 413999003910 bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404 413999003911 Cupin; Region: Cupin_1; smart00835 413999003912 Cupin; Region: Cupin_1; smart00835 413999003913 Pfam match to entry PF00190 Cupin, Cupin, score 44.9, E-value 1.9e-10 413999003914 Pfam match to entry PF00190 Cupin, Cupin, score 51.8, E-value 1.6e-12 413999003915 TIGR00730 family protein; Region: TIGR00730 413999003916 Pfam match to entry PF03641 Lysine_decarbox, Lysine decarboxylase, score 202.2, E-value 8.6e-58 413999003917 Protein of unknown function, DUF606; Region: DUF606; pfam04657 413999003918 5 probable transmembrane helices predicted for CBO0866 by TMHMM2.0 at aa 15-37, 50-72, 87-109, 116-138 and 142-164 413999003919 Pfam match to entry PF04657 DUF606, Protein of unknown function, DUF606, score 113.5, E-value 4.2e-31 413999003920 Transcriptional regulator [Transcription]; Region: LysR; COG0583 413999003921 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 413999003922 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 413999003923 dimerization interface [polypeptide binding]; other site 413999003924 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 73.8, E-value 3.8e-19 413999003925 Predicted helix-turn-helix motif with score 1742.000, SD 5.12 at aa 18-39, sequence GSISKAAKELFTSQPAVSQSIK 413999003926 PS00044 Bacterial regulatory proteins, lysR family signature. 413999003927 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain, score 100.0, E-value 4.8e-27 413999003928 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 413999003929 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999003930 Coenzyme A binding pocket [chemical binding]; other site 413999003931 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 34.2, E-value 3.2e-07 413999003932 HAD-hyrolase-like; Region: Hydrolase_like; pfam13242 413999003933 Protein of unknown function, DUF606; Region: DUF606; pfam04657 413999003934 3 probable transmembrane helices predicted for CBO0870 by TMHMM2.0 at aa 12-34, 49-71 and 96-118 413999003935 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 413999003936 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 413999003937 putative switch regulator; other site 413999003938 DNA binding site [nucleotide binding] 413999003939 sequence specific DNA binding site [nucleotide binding]; other site 413999003940 putative cAMP binding site [chemical binding]; other site 413999003941 Predicted helix-turn-helix motif with score 1084.000, SD 2.88 at aa 68-89, sequence SSYLEIAQFLGTTYRHLNRTLK 413999003942 Predicted transcriptional regulator [Transcription]; Region: COG2378 413999003943 HTH domain; Region: HTH_11; pfam08279 413999003944 WYL domain; Region: WYL; pfam13280 413999003945 Predicted helix-turn-helix motif with score 1709.000, SD 5.01 at aa 19-40, sequence ISAIKLAEMFEVTPRTIYRDID 413999003946 Protein of unknown function (DUF3815); Region: DUF3815; pfam12821 413999003947 5 probable transmembrane helices predicted for CBO0874 by TMHMM2.0 at aa 5-24, 29-46, 53-71, 81-100 and 121-143 413999003948 Uncharacterized conserved protein [Function unknown]; Region: COG2966 413999003949 Protein of unknown function (DUF1212); Region: DUF1212; pfam06738 413999003950 4 probable transmembrane helices predicted for CBO0875 by TMHMM2.0 at aa 117-139, 154-176, 183-201 and 216-238 413999003951 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 413999003952 active site 413999003953 catalytic residues [active] 413999003954 metal binding site [ion binding]; metal-binding site 413999003955 Pfam match to entry PF01327 Pep_deformylase,Polypeptide deformylase, score 72.6, E-value 8.7e-19 413999003956 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999003957 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999003958 DNA-binding site [nucleotide binding]; DNA binding site 413999003959 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999003960 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999003961 homodimer interface [polypeptide binding]; other site 413999003962 catalytic residue [active] 413999003963 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 36.1, E-value 8.6e-08 413999003964 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999003965 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 413999003966 Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139 413999003967 putative FMN binding site [chemical binding]; other site 413999003968 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 100.8, E-value 2.8e-27 413999003969 Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600 413999003970 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 15.0, E-value 0.0011 413999003971 transcriptional antiterminator BglG; Provisional; Region: PRK09772 413999003972 CAT RNA binding domain; Region: CAT_RBD; smart01061 413999003973 PRD domain; Region: PRD; pfam00874 413999003974 PRD domain; Region: PRD; pfam00874 413999003975 Pfam match to entry PF03123 CAT_RBD, CAT RNA binding domain, score 66.7, E-value 5.2e-17 413999003976 Pfam match to entry PF00874 PRD, PRD domain, score 132.4, E-value 8.6e-37 413999003977 Pfam match to entry PF00874 PRD, PRD domain, score 100.4, E-value 3.6e-27 413999003978 PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995 413999003979 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999003980 active site turn [active] 413999003981 phosphorylation site [posttranslational modification] 413999003982 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999003983 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 413999003984 HPr interaction site; other site 413999003985 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999003986 active site 413999003987 phosphorylation site [posttranslational modification] 413999003988 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 67.9, E-value 2.2e-17 413999003989 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999003990 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 122.8, E-value 6.8e-34 413999003991 9 probable transmembrane helices predicted for CBO0881 by TMHMM2.0 at aa 108-130, 143-165, 175-192,205-227, 250-272, 293-315, 325-347, 385-407 and 427-449 413999003992 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 189.4, E-value 5.8e-54 413999003993 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999003994 beta-galactosidase; Region: BGL; TIGR03356 413999003995 Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046 413999003996 Pfam match to entry PF00232 Glyco_hydro_1, Glycosyl hydrolase 1, score 514.9, E-value 6.2e-152 413999003997 PS00653 Glycosyl hydrolases family 1 N-terminal signature. 413999003998 PS00572 Glycosyl hydrolases family 1 active site. 413999003999 phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108 413999004000 Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852 413999004001 Mg++ binding site [ion binding]; other site 413999004002 putative catalytic motif [active] 413999004003 putative substrate binding site [chemical binding]; other site 413999004004 9 probable transmembrane helices predicted for CBO0884 by TMHMM2.0 at aa 5-27, 47-69, 76-93, 113-135,147-169, 179-201, 222-244, 249-271 and 298-315 413999004005 Pfam match to entry PF00953 Glycos_transf_4,Glycosyl transferase, score 163.9, E-value 2.9e-46 413999004006 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999004007 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999004008 non-specific DNA binding site [nucleotide binding]; other site 413999004009 sequence-specific DNA binding site [nucleotide binding]; other site 413999004010 salt bridge; other site 413999004011 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 47.1, E-value 4.1e-11 413999004012 Predicted helix-turn-helix motif with score 1531.000, SD 4.40 at aa 63-84, sequence ITQKNLAKKIGVSEDLLSKYKS 413999004013 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 413999004014 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 413999004015 GyrI-like small molecule binding domain; Region: GyrI-like; cl01368 413999004016 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 413999004017 Multicopper oxidase; Region: Cu-oxidase_3; pfam07732 413999004018 Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132 413999004019 Multicopper oxidase; Region: Cu-oxidase; pfam00394 413999004020 Multicopper oxidase; Region: Cu-oxidase_2; pfam07731 413999004021 Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase, score 0.6, E-value 0.029 413999004022 2 probable transmembrane helices predicted for CBO0893 by TMHMM2.0 at aa 12-31 and 36-58 413999004023 Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113 413999004024 Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371 413999004025 Pfam match to entry PF04371 PAD_porph,Porphyromonas-type peptidyl-arginine deiminase, score 72.2, E-value 4.3e-20 413999004026 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 413999004027 GyrI-like small molecule binding domain; Region: GyrI-like; cl01368 413999004028 Predicted membrane protein [Function unknown]; Region: COG2510 413999004029 Predicted membrane protein [Function unknown]; Region: COG2510 413999004030 9 probable transmembrane helices predicted for CBO0896 by TMHMM2.0 at aa 2-24, 34-53, 66-88, 108-130,151-173, 183-200, 213-235, 240-262 and 269-286 413999004031 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 85.7, E-value 9.9e-23 413999004032 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 85.4, E-value 1.2e-22 413999004033 Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229 413999004034 Pfam match to entry PF04229 UPF0157,Uncharacterised protein family (UPF0157), score 84.7,E-value 2e-22 413999004035 Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376 413999004036 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 413999004037 Pfam match to entry PF03734 ErfK_YbiS_YhnG,ErfK/YbiS/YcfS/YnhG, score 142.2, E-value 9.5e-40 413999004038 YmaF family; Region: YmaF; pfam12788 413999004039 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 413999004040 Amino acid permease; Region: AA_permease_2; pfam13520 413999004041 3 probable transmembrane helices predicted for CBO0903 by TMHMM2.0 at aa 5-27, 32-54 and 61-83 413999004042 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999004043 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999004044 Walker A/P-loop; other site 413999004045 ATP binding site [chemical binding]; other site 413999004046 Q-loop/lid; other site 413999004047 ABC transporter signature motif; other site 413999004048 Walker B; other site 413999004049 D-loop; other site 413999004050 H-loop/switch region; other site 413999004051 ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591 413999004052 FtsX-like permease family; Region: FtsX; pfam02687 413999004053 Pfam match to entry PF02687 FtsX, Predicted permease, score 128.9, E-value 1e-35 413999004054 3 probable transmembrane helices predicted for CBO0904 by TMHMM2.0 at aa 660-682, 707-729 and 749-771 413999004055 Predicted helix-turn-helix motif with score 1004.000, SD 2.61 at aa 302-323, sequence ISIEQNSMSLGMSPSSKSKDKE 413999004056 Pfam match to entry PF00005 ABC_tran, ABC transporter score 212.2, E-value 8.1e-61 413999004057 PS00211 ABC transporters family signature. 413999004058 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004059 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999004060 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999004061 active site 413999004062 phosphorylation site [posttranslational modification] 413999004063 intermolecular recognition site; other site 413999004064 dimerization interface [polypeptide binding]; other site 413999004065 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999004066 DNA binding site [nucleotide binding] 413999004067 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 130.1, E-value 4.2e-36 413999004068 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 68.5, E-value 1.5e-17 413999004069 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999004070 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999004071 dimerization interface [polypeptide binding]; other site 413999004072 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999004073 dimer interface [polypeptide binding]; other site 413999004074 phosphorylation site [posttranslational modification] 413999004075 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999004076 ATP binding site [chemical binding]; other site 413999004077 Mg2+ binding site [ion binding]; other site 413999004078 G-X-G motif; other site 413999004079 2 probable transmembrane helices predicted for CBO0906 by TMHMM2.0 at aa 13-35 and 48-70 413999004080 Pfam match to entry PF00672 HAMP, HAMP domain,score 55.6, E-value 1.1e-13 413999004081 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 77.2, E-value 3.6e-20 413999004082 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 123.2, E-value 4.9e-34 413999004083 BioY family; Region: BioY; pfam02632 413999004084 6 probable transmembrane helices predicted for CBO0907 by TMHMM2.0 at aa 13-32, 36-58, 63-85, 90-107,114-136 and 146-168 413999004085 Pfam match to entry PF02632 BioY, BioY family,score 129.5, E-value 6.4e-36 413999004086 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999004087 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 413999004088 Sel1 repeat; Region: Sel1; pfam08238 413999004089 Sel1-like repeats; Region: SEL1; smart00671 413999004090 Sel1-like repeats; Region: SEL1; smart00671 413999004091 Sel1-like repeats; Region: SEL1; smart00671 413999004092 putative acetyltransferase YhhY; Provisional; Region: PRK10140 413999004093 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999004094 Coenzyme A binding pocket [chemical binding]; other site 413999004095 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 76.6, E-value 5.5e-20 413999004096 LexA repressor; Validated; Region: PRK00215 413999004097 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 413999004098 Catalytic site [active] 413999004099 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004100 Pfam match to entry PF00717 Peptidase_S24,Peptidase S24, score 89.3, E-value 8e-24 413999004101 Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544 413999004102 homotrimer interface [polypeptide binding]; other site 413999004103 Walker A motif; other site 413999004104 GTP binding site [chemical binding]; other site 413999004105 Walker B motif; other site 413999004106 Pfam match to entry PF02283 CobU, Cobinamide kinase / cobinamide phosphate guanyltransferase, score 186.5,E-value 4.6e-53 413999004107 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004108 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999004109 Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106 413999004110 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999004111 DNA binding residues [nucleotide binding] 413999004112 dimer interface [polypeptide binding]; other site 413999004113 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 413999004114 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 51.6, E-value 1.8e-12 413999004115 Predicted helix-turn-helix motif with score 1396.000, SD 3.94 at aa 3-24, sequence YKIKEVADMAGISVRMLHHYDK 413999004116 cobyric acid synthase; Provisional; Region: PRK00784 413999004117 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999004118 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999004119 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750 413999004120 catalytic triad [active] 413999004121 Pfam match to entry PF01656 CbiA, Cobyrinic acid a,c-diamide synthase, score 287.7, E-value 1.5e-83 413999004122 cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209 413999004123 Pfam match to entry PF03186 CobD_Cbib, CobD/Cbib protein, score 334.7, E-value 1.1e-97 413999004124 4 probable transmembrane helices predicted for CBO0915 by TMHMM2.0 at aa 59-81, 86-108, 160-182 and 212-234 413999004125 threonine-phosphate decarboxylase; Provisional; Region: PRK06358 413999004126 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999004127 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999004128 homodimer interface [polypeptide binding]; other site 413999004129 catalytic residue [active] 413999004130 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 10.3, E-value 2.9e-06 413999004131 cobalt transport protein CbiM; Validated; Region: PRK08319 413999004132 Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891 413999004133 7 probable transmembrane helices predicted for CBO0917 by TMHMM2.0 at aa 5-27, 37-54, 67-89, 99-121,128-150, 160-182 and 202-224 413999004134 Pfam match to entry PF01891 CbiM, CbiM, score 286.1, E-value 4.5e-83 413999004135 cobalt transport protein CbiN; Provisional; Region: PRK02898 413999004136 cobalt ABC transporter, permease protein CbiQ; Region: CbiQ_TIGR; TIGR02454 413999004137 4 probable transmembrane helices predicted for CBO0918 by TMHMM2.0 at aa 22-44, 57-78, 82-104 and 205-226 413999004138 precorrin-2 dehydrogenase; Provisional; Region: PRK05562 413999004139 Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241 413999004140 porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072 413999004141 Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494 413999004142 domain interfaces; other site 413999004143 active site 413999004144 Pfam match to entry PF01379 Porphobil_deam,Porphobilinogen deaminase, dipyromethane cofactor binding domain, score 362.6, E-value 4.4e-106 413999004145 Pfam match to entry PF03900 Porphobil_deamC,Porphobilinogen deaminase, C-terminal domain, score 49.5,E-value 7.7e-12 413999004146 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 413999004147 active site 413999004148 SAM binding site [chemical binding]; other site 413999004149 homodimer interface [polypeptide binding]; other site 413999004150 Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587 413999004151 Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578 413999004152 active site 413999004153 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 220.0,E-value 3.6e-63 413999004154 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 413999004155 PS00840 Uroporphyrin-III C-methyltransferase signature 2. 413999004156 Pfam match to entry PF02602 HEM4,Uroporphyrinogen-III synthase HemD, score 114.1, E-value 2.8e-31 413999004157 Predicted helix-turn-helix motif with score 1023.000, SD 2.67 at aa 416-437, sequence ERFEDADTVLFTSPSTVRNMIS 413999004158 Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384 413999004159 dimer interface [polypeptide binding]; other site 413999004160 active site 413999004161 Schiff base residues; other site 413999004162 Pfam match to entry PF00490 ALAD,Delta-aminolevulinic acid dehydratase, score 678.2,E-value 4.2e-201 413999004163 PS00169 Delta-aminolevulinic acid dehydratase active site. 413999004164 cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077 413999004165 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999004166 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130 413999004167 catalytic triad [active] 413999004168 Pfam match to entry PF01656 CbiA, Cobyrinic acid a,c-diamide synthase, score 128.7, E-value 1.1e-35 413999004169 precorrin-8X methylmutase; Validated; Region: cbiC; PRK05575 413999004170 cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913 413999004171 Pfam match to entry PF02570 CbiC, Precorrin-8X methylmutase, score 204.8, E-value 1.4e-58 413999004172 CAAX protease self-immunity; Region: Abi; pfam02517 413999004173 8 probable transmembrane helices predicted for CBO0926 by TMHMM2.0 at aa 12-34, 39-61, 82-104, 119-141,153-171, 176-193, 200-222 and 242-264 413999004174 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 68.4, E-value 1.5e-17 413999004175 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999004176 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 413999004177 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999004178 Zn2+ binding site [ion binding]; other site 413999004179 Mg2+ binding site [ion binding]; other site 413999004180 Pfam match to entry PF01966 HD, HD domain, score 23.1, E-value 0.00019 413999004181 Predicted helix-turn-helix motif with score 1688.000, SD 4.94 at aa 152-173, sequence KRFVDVACRYGVNEYTIARWKK 413999004182 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 413999004183 Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592 413999004184 DNA binding residues [nucleotide binding] 413999004185 dimer interface [polypeptide binding]; other site 413999004186 Predicted helix-turn-helix motif with score 1631.000, SD 4.74 at aa 1-22, sequence MKIKDAERLTGLSQKTIRYYES 413999004187 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 26.4, E-value 7.1e-05 413999004188 5 probable transmembrane helices predicted for CBO0930 by TMHMM2.0 at aa 142-161, 171-193, 205-224,244-266 and 287-309 413999004189 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999004190 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 51.4, E-value 2e-12 413999004191 Fic family protein [Function unknown]; Region: COG3177 413999004192 Fic/DOC family; Region: Fic; pfam02661 413999004193 Pfam match to entry PF02661 Fic, Fic protein family, score 80.8, E-value 3e-21 413999004194 Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514 413999004195 FMN binding site [chemical binding]; other site 413999004196 dimer interface [polypeptide binding]; other site 413999004197 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 100.5, E-value 3.5e-27 413999004198 3 probable transmembrane helices predicted for CBO0934 by TMHMM2.0 at aa 4-26, 47-61 and 76-98 413999004199 Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229 413999004200 Pfam match to entry PF04229 UPF0157,Uncharacterised protein family (UPF0157), score 169.3,E-value 6.6e-48 413999004201 cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075 413999004202 Pfam match to entry PF01888 CbiD, CbiD, score 328.1, E-value 1.1e-95 413999004203 Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644 413999004204 active site 413999004205 putative homodimer interface [polypeptide binding]; other site 413999004206 SAM binding site [chemical binding]; other site 413999004207 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 16.7,E-value 3.7e-06 413999004208 CAAX protease self-immunity; Region: Abi; pfam02517 413999004209 4 probable transmembrane helices predicted for CBO0938 by TMHMM2.0 at aa 21-40, 44-66, 71-90 and 100-122 413999004210 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 40.1, E-value 5.3e-09 413999004211 Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242 413999004212 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999004213 S-adenosylmethionine binding site [chemical binding]; other site 413999004214 6 probable transmembrane helices predicted for CBO0941 by TMHMM2.0 at aa 17-36, 46-63, 76-98, 108-125,130-148 and 152-170 413999004215 2 probable transmembrane helices predicted for CBO0942 by TMHMM2.0 at aa 16-32 and 47-69 413999004216 3 probable transmembrane helices predicted for CBO0943 by TMHMM2.0 at aa 4-21, 33-55 and 59-78 413999004217 hypothetical protein; Provisional; Region: PRK06771 413999004218 2 probable transmembrane helices predicted for CBO0944 by TMHMM2.0 at aa 5-22 and 29-48 413999004219 Isochorismatase family; Region: Isochorismatase; pfam00857 413999004220 Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014 413999004221 catalytic triad [active] 413999004222 conserved cis-peptide bond; other site 413999004223 Pfam match to entry PF00857 Isochorismatase,Isochorismatase, score 31.7, E-value 3.9e-10 413999004224 Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645 413999004225 active site 413999004226 SAM binding site [chemical binding]; other site 413999004227 homodimer interface [polypeptide binding]; other site 413999004228 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 77.0,E-value 4.1e-20 413999004229 Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641 413999004230 active site 413999004231 SAM binding site [chemical binding]; other site 413999004232 homodimer interface [polypeptide binding]; other site 413999004233 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 175.3,E-value 1.1e-49 413999004234 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 413999004235 cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788 413999004236 Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760 413999004237 Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761 413999004238 Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890 413999004239 Pfam match to entry PF01890 CbiG, CbiG, score 195.7, E-value 7.5e-56 413999004240 Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646 413999004241 active site 413999004242 SAM binding site [chemical binding]; other site 413999004243 homodimer interface [polypeptide binding]; other site 413999004244 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 135.4,E-value 1.1e-37 413999004245 cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057 413999004246 Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099 413999004247 Pfam match to entry PF02571 CbiJ, Precorrin-6x reductase CbiJ/CobK, score 156.0, E-value 6.8e-44 413999004248 ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272 413999004249 Protein of unknown function (DUF3816); Region: DUF3816; pfam12822 413999004250 5 probable transmembrane helices predicted for CBO0951 by TMHMM2.0 at aa 5-22, 35-57, 67-89, 102-124 and 128-150 413999004251 Cobalt chelatase (CbiK); Region: CbiK; pfam06180 413999004252 Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412 413999004253 active site 413999004254 C-terminal domain interface [polypeptide binding]; other site 413999004255 Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413 413999004256 active site 413999004257 N-terminal domain interface [polypeptide binding]; other site 413999004258 Pfam match to entry PF06180 CbiK, Cobalt chelatase (CbiK), score 384.5, E-value 1.1e-112 413999004259 PS00761 Signal peptidases I signature 3. 413999004260 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542 413999004261 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 413999004262 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein, score 36.7, E-value 5.5e-08 413999004263 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109 413999004264 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561 413999004265 homodimer interface [polypeptide binding]; other site 413999004266 Walker A motif; other site 413999004267 ATP binding site [chemical binding]; other site 413999004268 hydroxycobalamin binding site [chemical binding]; other site 413999004269 Walker B motif; other site 413999004270 Pfam match to entry PF02572 CobA_CobO_BtuR,ATP:corrinoid adenosyltransferase BtuR/CobO/CobP, score 208.4, E-value 1.1e-59 413999004271 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 413999004272 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 413999004273 ligand binding site [chemical binding]; other site 413999004274 flexible hinge region; other site 413999004275 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 413999004276 putative switch regulator; other site 413999004277 non-specific DNA interactions [nucleotide binding]; other site 413999004278 DNA binding site [nucleotide binding] 413999004279 sequence specific DNA binding site [nucleotide binding]; other site 413999004280 putative cAMP binding site [chemical binding]; other site 413999004281 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain, score 55.7, E-value 1.1e-13 413999004282 Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family, score 27.7, E-value 2.9e-05 413999004283 Predicted helix-turn-helix motif with score 1854.000, SD 5.50 at aa 184-205, sequence ITVTYLSEMLGSSRETISRALK 413999004284 Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226 413999004285 Pfam match to entry PF01226 Form_Nir_trans,Formate/nitrite transporter score 254.6, E-value 1.5e-73 413999004286 6 probable transmembrane helices predicted for CBO0956 by TMHMM2.0 at aa 25-47, 62-84, 105-127, 155-174,187-209 and 224-246 413999004287 PS01005 Formate and nitrite transporters signature 1. 413999004288 PS01006 Formate and nitrite transporters signature 2. 413999004289 anaerobic sulfite reductase subunit A; Provisional; Region: PRK15055 413999004290 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999004291 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 11.7, E-value 0.0037 413999004292 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999004293 anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221 413999004294 Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221 413999004295 FAD binding pocket [chemical binding]; other site 413999004296 FAD binding motif [chemical binding]; other site 413999004297 phosphate binding motif [ion binding]; other site 413999004298 beta-alpha-beta structure motif; other site 413999004299 NAD binding pocket [chemical binding]; other site 413999004300 Iron coordination center [ion binding]; other site 413999004301 Pfam match to entry PF00970 FAD_binding_6,Oxidoreductase FAD-binding domain, score 20.7, E-value 2.1e-06 413999004302 Pfam match to entry PF00175 NAD_binding_1,Oxidoreductase NAD-binding domain, score 61.4, E-value 2e-15 413999004303 sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912 413999004304 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 413999004305 Pfam match to entry PF03460 NIR_SIR_ferr,Nitrite/Sulfite reductase ferredoxin-like half domain,score 61.1, E-value 2.5e-15 413999004306 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain, score 66.9, E-value 4.5e-17 413999004307 PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 413999004308 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 16.4, E-value 0.00066 413999004309 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 35.6, E-value 1.2e-07 413999004310 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999004311 MoeA_like. This domain is similar to a domain found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. There this domain is presumed to bind molybdopterin. The exact function of this subgroup is...; Region: MoeA_like; cd03522 413999004312 putative MPT binding site; other site 413999004313 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain, score 110.6, E-value 3.2e-30 413999004314 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 413999004315 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 413999004316 substrate binding pocket [chemical binding]; other site 413999004317 membrane-bound complex binding site; other site 413999004318 hinge residues; other site 413999004319 1 probable transmembrane helix predicted for CBO0961 by TMHMM2.0 at aa 7-25 413999004320 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 25.6, E-value 0.00012 413999004321 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999004322 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 413999004323 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999004324 dimer interface [polypeptide binding]; other site 413999004325 conserved gate region; other site 413999004326 putative PBP binding loops; other site 413999004327 ABC-ATPase subunit interface; other site 413999004328 6 probable transmembrane helices predicted for CBO0962 by TMHMM2.0 at aa 7-29, 56-75, 87-109, 124-143,185-207 and 233-255 413999004329 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 36.6, E-value 6.1e-08 413999004330 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999004331 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999004332 Walker A/P-loop; other site 413999004333 ATP binding site [chemical binding]; other site 413999004334 Q-loop/lid; other site 413999004335 ABC transporter signature motif; other site 413999004336 Walker B; other site 413999004337 D-loop; other site 413999004338 H-loop/switch region; other site 413999004339 Pfam match to entry PF00005 ABC_tran, ABC transporter score 174.2, E-value 2.3e-49 413999004340 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004341 PS00211 ABC transporters family signature. 413999004342 Domain of unknown function (DUF364); Region: DUF364; pfam04016 413999004343 1 probable transmembrane helix predicted for CBO0964 by TMHMM2.0 at aa 218-240 413999004344 6 probable transmembrane helices predicted for CBO0966 by TMHMM2.0 at aa 13-32, 116-138, 164-186,223-241, 248-270 and 311-333 413999004345 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999004346 ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264 413999004347 Walker A/P-loop; other site 413999004348 ATP binding site [chemical binding]; other site 413999004349 Q-loop/lid; other site 413999004350 ABC transporter signature motif; other site 413999004351 Walker B; other site 413999004352 D-loop; other site 413999004353 H-loop/switch region; other site 413999004354 Pfam match to entry PF00005 ABC_tran, ABC transporter score 187.9, E-value 1.7e-53 413999004355 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004356 PS00211 ABC transporters family signature. 413999004357 6 probable transmembrane helices predicted for CBO0968 by TMHMM2.0 at aa 13-32, 52-71, 98-120, 150-172,179-201 and 228-250 413999004358 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999004359 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999004360 active site 413999004361 phosphorylation site [posttranslational modification] 413999004362 intermolecular recognition site; other site 413999004363 dimerization interface [polypeptide binding]; other site 413999004364 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999004365 DNA binding site [nucleotide binding] 413999004366 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 121.9, E-value 1.3e-33 413999004367 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 83.0, E-value 6.3e-22 413999004368 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999004369 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999004370 dimer interface [polypeptide binding]; other site 413999004371 phosphorylation site [posttranslational modification] 413999004372 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999004373 ATP binding site [chemical binding]; other site 413999004374 G-X-G motif; other site 413999004375 2 probable transmembrane helices predicted for CBO0971 by TMHMM2.0 at aa 15-37 and 170-192 413999004376 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 67.3, E-value 3.4e-17 413999004377 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 101.4, E-value 1.9e-27 413999004378 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 413999004379 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999004380 Walker A/P-loop; other site 413999004381 ATP binding site [chemical binding]; other site 413999004382 Q-loop/lid; other site 413999004383 ABC transporter signature motif; other site 413999004384 Walker B; other site 413999004385 D-loop; other site 413999004386 H-loop/switch region; other site 413999004387 Pfam match to entry PF00005 ABC_tran, ABC transporter score 181.3, E-value 1.7e-51 413999004388 PS00211 ABC transporters family signature. 413999004389 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004390 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 413999004391 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999004392 ABC-ATPase subunit interface; other site 413999004393 dimer interface [polypeptide binding]; other site 413999004394 putative PBP binding regions; other site 413999004395 Pfam match to entry PF01032 FecCD, FecCD transport family, score 363.0, E-value 3.3e-106 413999004396 10 probable transmembrane helices predicted for CBO0973 by TMHMM2.0 at aa 20-42, 80-99, 111-133, 137-159,171-193, 213-235, 242-264, 269-291, 304-326 and 331-348 413999004397 Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148 413999004398 proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868 413999004399 putative ligand binding residues [chemical binding]; other site 413999004400 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 45.2, E-value 1.6e-10 413999004401 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999004402 dihydroxyacetone kinase; Provisional; Region: PRK14479 413999004403 dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481 413999004404 DAK2 domain; Region: Dak2; pfam02734 413999004405 Pfam match to entry PF02734 Dak2, DAK2 domain,score 80.7, E-value 3.1e-21 413999004406 Pfam match to entry PF02733 Dak1, Dak1 domain,score 488.0, E-value 7.8e-144 413999004407 Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371 413999004408 Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170 413999004409 dimer interface [polypeptide binding]; other site 413999004410 active site 413999004411 metal binding site [ion binding]; metal-binding site 413999004412 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 151.7, E-value 1.4e-42 413999004413 PS00913 Iron-containing alcohol dehydrogenases signature 1. 413999004414 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 33.3, E-value 5.7e-07 413999004415 PS00041 Bacterial regulatory proteins, araC family signature. 413999004416 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 29.8, E-value 6.8e-06 413999004417 Predicted helix-turn-helix motif with score 1853.000, SD 5.50 at aa 52-73, sequence ITAKKLAEVCHISPSYFSRLFA 413999004418 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 413999004419 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999004420 Coenzyme A binding pocket [chemical binding]; other site 413999004421 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 61.5, E-value 1.9e-15 413999004422 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999004423 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 413999004424 Coenzyme A binding pocket [chemical binding]; other site 413999004425 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 44.3, E-value 2.9e-10 413999004426 Protein of unknown function (DUF1349); Region: DUF1349; pfam07081 413999004427 Protein of unknown function (DUF3788); Region: DUF3788; pfam12663 413999004428 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 413999004429 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 413999004430 active site 413999004431 catalytic tetrad [active] 413999004432 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase, score 440.2, E-value 1.9e-129 413999004433 PS00062 Aldo/keto reductase signature 2. 413999004434 PS00063 Aldo/keto reductase active site signature. 413999004435 TfoX N-terminal domain; Region: TfoX_N; pfam04993 413999004436 Pfam match to entry PF04993 TfoX_N, TfoX N-terminal domain, score 117.3, E-value 3.1e-32 413999004437 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 413999004438 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999004439 Protein of unknown function (DUF1462); Region: DUF1462; cl11552 413999004440 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999004441 Coenzyme A binding pocket [chemical binding]; other site 413999004442 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 43.6, E-value 4.6e-10 413999004443 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 22.9, E-value 0.00078 413999004444 Predicted transcriptional regulators [Transcription]; Region: COG1695 413999004445 Transcriptional regulator PadR-like family; Region: PadR; cl17335 413999004446 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family, score 35.6, E-value 1.2e-07 413999004447 Protein of unknown function (DUF2812); Region: DUF2812; pfam11193 413999004448 2 probable transmembrane helices predicted for CBO0988 by TMHMM2.0 at aa 114-136 and 169-191 413999004449 Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816 413999004450 Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320 413999004451 active site 413999004452 purine riboside binding site [chemical binding]; other site 413999004453 Pfam match to entry PF00962 A_deaminase,Adenosine/AMP deaminase, score 241.2, E-value 1.5e-69 413999004454 Predicted membrane protein [Function unknown]; Region: COG1511 413999004455 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 413999004456 Predicted membrane protein [Function unknown]; Region: COG1511 413999004457 YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062 413999004458 6 probable transmembrane helices predicted for CBO0992 by TMHMM2.0 at aa 21-43, 520-542, 562-581,586-608, 615-637 and 678-700 413999004459 Predicted membrane protein [Function unknown]; Region: COG1511 413999004460 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 413999004461 Fibrinogen alpha/beta chain family; Region: Fib_alpha; pfam08702 413999004462 YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062 413999004463 6 probable transmembrane helices predicted for CBO0993 by TMHMM2.0 at aa 21-38, 522-544, 565-587,597-619, 626-645 and 677-699 413999004464 Domain of unknown function (DUF4184); Region: DUF4184; pfam13803 413999004465 5 probable transmembrane helices predicted for CBO0994 by TMHMM2.0 at aa 48-70, 101-123, 156-175, 196-218 and 228-250 413999004466 ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389 413999004467 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999004468 ATP binding site [chemical binding]; other site 413999004469 putative Mg++ binding site [ion binding]; other site 413999004470 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999004471 nucleotide binding region [chemical binding]; other site 413999004472 ATP-binding site [chemical binding]; other site 413999004473 This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956 413999004474 HRDC domain; Region: HRDC; pfam00570 413999004475 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 136.4, E-value 5.4e-38 413999004476 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 105.0, E-value 1.6e-28 413999004477 Pfam match to entry PF00570 HRDC, HRDC domain,score 74.9, E-value 1.7e-19 413999004478 rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046 413999004479 Rubrerythrin [Energy production and conversion]; Region: COG1592 413999004480 diiron binding motif [ion binding]; other site 413999004481 Pfam match to entry PF02915 Rubrerythrin,Rubrerythrin, score 106.8, E-value 4.3e-29 413999004482 Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841 413999004483 active site 413999004484 metal binding site [ion binding]; metal-binding site 413999004485 homotetramer interface [polypeptide binding]; other site 413999004486 Pfam match to entry PF00149 Metallophos,Calcineurin-like phosphoesterase, score 68.6, E-value 1.4e-17 413999004487 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 413999004488 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999004489 active site 413999004490 phosphorylation site [posttranslational modification] 413999004491 intermolecular recognition site; other site 413999004492 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 62.2, E-value 1.1e-15 413999004493 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999004494 TPR repeat; Region: TPR_11; pfam13414 413999004495 TPR motif; other site 413999004496 binding surface 413999004497 Protein of unknown function (DUF3298); Region: DUF3298; pfam11738 413999004498 PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature. 413999004499 Protein of unknown function (DUF2997); Region: DUF2997; pfam11211 413999004500 putative membrane protein, TIGR04086 family; Region: TIGR04086_membr 413999004501 Helix-hairpin-helix motif; Region: HHH_3; pfam12836 413999004502 3 probable transmembrane helices predicted for CBO1001 by TMHMM2.0 at aa 15-34, 43-62 and 66-88 413999004503 4Fe-4S single cluster domain; Region: Fer4_12; pfam13353 413999004504 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999004505 FeS/SAM binding site; other site 413999004506 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 14.0, E-value 0.025 413999004507 Ycf46; Provisional; Region: ycf46; CHL00195 413999004508 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999004509 Walker A motif; other site 413999004510 ATP binding site [chemical binding]; other site 413999004511 Walker B motif; other site 413999004512 arginine finger; other site 413999004513 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 175.3, E-value 1e-49 413999004514 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004515 L-lactate permease [Energy production and conversion]; Region: LldP; COG1620 413999004516 L-lactate permease; Region: Lactate_perm; cl00701 413999004517 12 probable transmembrane helices predicted for CBO1005 by TMHMM2.0 at aa 5-24, 36-58, 62-84, 105-127,142-164, 177-199, 234-256, 277-299, 322-344, 364-386,390-412 and 486-505 413999004518 Pfam match to entry PF02652 Lactate_perm, L-lactate permease, score 554.5, E-value 7.3e-164 413999004519 Domain of unknown function (DUF2088); Region: DUF2088; cl15406 413999004520 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 413999004521 Ligand binding site [chemical binding]; other site 413999004522 Electron transfer flavoprotein domain; Region: ETF; pfam01012 413999004523 Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit, score 279.0, E-value 6.3e-81 413999004524 Ferredoxin [Energy production and conversion]; Region: NapF; COG1145 413999004525 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 413999004526 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 413999004527 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 413999004528 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit, score 323.6, E-value 2.5e-94 413999004529 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 413999004530 FAD binding domain; Region: FAD_binding_4; pfam01565 413999004531 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain, score 244.0, E-value 2.2e-70 413999004532 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain, score 272.0, E-value 8.4e-79 413999004533 1 probable transmembrane helix predicted for CBO1011 by TMHMM2.0 at aa 7-24 413999004534 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999004535 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999004536 Pfam match to entry PF01047 MarR, MarR family,score 67.9, E-value 2.2e-17 413999004537 Predicted helix-turn-helix motif with score 1293.000, SD 3.59 at aa 53-74, sequence PNVTKISENMNMTRGAISKICK 413999004538 Putative cyclase; Region: Cyclase; pfam04199 413999004539 Pfam match to entry PF04199 Cyclase, cyclase, score -18.3, E-value 0.00044 413999004540 aspartate aminotransferase; Provisional; Region: PRK06836 413999004541 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999004542 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999004543 homodimer interface [polypeptide binding]; other site 413999004544 catalytic residue [active] 413999004545 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 108.8, E-value 1.1e-29 413999004546 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 413999004547 Putative cyclase; Region: Cyclase; pfam04199 413999004548 Putative cyclase; Region: Cyclase; cl00814 413999004549 Pfam match to entry PF04199 Cyclase, cyclase, score 23.9, E-value 7.3e-07 413999004550 Winged helix DNA-binding domain; Region: HTH_27; pfam13463 413999004551 Pfam match to entry PF01047 MarR, MarR family,score 69.5, E-value 7.6e-18 413999004552 Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107 413999004553 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999004554 DNA binding residues [nucleotide binding] 413999004555 drug binding residues [chemical binding]; other site 413999004556 dimer interface [polypeptide binding]; other site 413999004557 Transcriptional regulator, effector-binding domain/component [Transcription / Signal transduction mechanisms]; Region: COG4978 413999004558 Predicted helix-turn-helix motif with score 1442.000, SD 4.10 at aa 5-26, sequence FTIGEISKLFNINIRTLRYYDE 413999004559 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 50.6, E-value 3.7e-12 413999004560 Predicted helix-turn-helix motif with score 1442.000, SD 4.10 at aa 52-26, sequence EIDLFKPIFIDKANSYRYYSTDQFEQL 413999004561 Predicted helix-turn-helix motif with score 1265.000, SD 3.50 at aa 52-73, sequence LNTIKYLKALGMSLDTISYHLK 413999004562 Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382 413999004563 B3/4 domain; Region: B3_4; pfam03483 413999004564 Pfam match to entry PF03483 B3_4, B3/4 domain,score 29.9, E-value 6.4e-08 413999004565 aspartyl-tRNA synthetase; Provisional; Region: aspC; PRK05159 413999004566 Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930 413999004567 Dimer interface [polypeptide binding]; other site 413999004568 anticodon binding site; other site 413999004569 Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776 413999004570 homodimer interface [polypeptide binding]; other site 413999004571 motif 1; other site 413999004572 motif 2; other site 413999004573 active site 413999004574 motif 3; other site 413999004575 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N), score 261.8, E-value 9.8e-76 413999004576 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 65.8, E-value 9.7e-17 413999004577 flavodoxin; Provisional; Region: PRK06242 413999004578 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999004579 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999004580 WHG domain; Region: WHG; pfam13305 413999004581 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 50.0, E-value 5.5e-12 413999004582 Predicted helix-turn-helix motif with score 1565.000, SD 4.52 at aa 50-71, sequence LSIRKIANKIEYSPGIIYHYFK 413999004583 Flavodoxin domain; Region: Flavodoxin_5; pfam12724 413999004584 dUMP phosphatase; Provisional; Region: PRK09449 413999004585 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999004586 motif II; other site 413999004587 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 87.8, E-value 2.3e-23 413999004588 DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402 413999004589 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 413999004590 ligand binding site [chemical binding]; other site 413999004591 flexible hinge region; other site 413999004592 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 413999004593 putative switch regulator; other site 413999004594 DNA binding site [nucleotide binding] 413999004595 sequence specific DNA binding site [nucleotide binding]; other site 413999004596 putative cAMP binding site [chemical binding]; other site 413999004597 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain, score 32.4, E-value 1.1e-06 413999004598 Predicted helix-turn-helix motif with score 1162.000, SD 3.14 at aa 173-194, sequence SSFLEIAQFLGTTYRHLNRTFK 413999004599 DJ-1 family protein; Region: not_thiJ; TIGR01383 413999004600 Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135 413999004601 conserved cys residue [active] 413999004602 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family, score 74.1, E-value 3.1e-19 413999004603 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004604 Transcriptional regulator [Transcription]; Region: LysR; COG0583 413999004605 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 413999004606 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 413999004607 dimerization interface [polypeptide binding]; other site 413999004608 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 77.4, E-value 3.2e-20 413999004609 Predicted helix-turn-helix motif with score 1544.000, SD 4.45 at aa 16-37, sequence EGFTKAAEYLGYAQSTITSHIQ 413999004610 PS00044 Bacterial regulatory proteins, lysR family signature. 413999004611 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain, score 113.0, E-value 5.8e-31 413999004612 YoaP-like; Region: YoaP; pfam14268 413999004613 FeoA domain; Region: FeoA; pfam04023 413999004614 Pfam match to entry PF04023 FeoA, FeoA family,score 36.2, E-value 7.8e-08 413999004615 Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918 413999004616 Pfam match to entry PF04023 FeoA, FeoA family,score 71.3, E-value 2.1e-18 413999004617 Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370 413999004618 Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879 413999004619 G1 box; other site 413999004620 GTP/Mg2+ binding site [chemical binding]; other site 413999004621 Switch I region; other site 413999004622 G2 box; other site 413999004623 G3 box; other site 413999004624 Switch II region; other site 413999004625 G4 box; other site 413999004626 G5 box; other site 413999004627 Nucleoside recognition; Region: Gate; pfam07670 413999004628 Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664 413999004629 Nucleoside recognition; Region: Gate; pfam07670 413999004630 Pfam match to entry PF02421 FeoB, Ferrous iron transport protein B, score 872.2, E-value 1.7e-259 413999004631 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004632 10 probable transmembrane helices predicted for CBO1030 by TMHMM2.0 at aa 283-305, 320-342, 349-371,397-414, 427-449, 453-475, 520-542, 615-637, 650-672 and 677-696 413999004633 1 probable transmembrane helix predicted for CBO1031 by TMHMM2.0 at aa 4-22 413999004634 PS00118 Phospholipase A2 histidine active site. 413999004635 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 413999004636 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999004637 Coenzyme A binding pocket [chemical binding]; other site 413999004638 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 32.2, E-value 1.3e-06 413999004639 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876 413999004640 D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557 413999004641 Pfam match to entry PF02557 VanY,D-alanyl-D-alanine carboxypeptidase, score 170.7, E-value 2.6e-48 413999004642 small acid-soluble spore protein Tlp; Provisional; Region: PRK03830 413999004643 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999004644 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999004645 active site 413999004646 phosphorylation site [posttranslational modification] 413999004647 intermolecular recognition site; other site 413999004648 dimerization interface [polypeptide binding]; other site 413999004649 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999004650 DNA binding site [nucleotide binding] 413999004651 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 121.1, E-value 2.2e-33 413999004652 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 83.2, E-value 5.7e-22 413999004653 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999004654 dimer interface [polypeptide binding]; other site 413999004655 phosphorylation site [posttranslational modification] 413999004656 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999004657 ATP binding site [chemical binding]; other site 413999004658 Mg2+ binding site [ion binding]; other site 413999004659 G-X-G motif; other site 413999004660 2 probable transmembrane helices predicted for CBO1036 by TMHMM2.0 at aa 10-32 and 155-174 413999004661 Pfam match to entry PF00672 HAMP, HAMP domain,score 22.2, E-value 0.0013 413999004662 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 52.2, E-value 1.2e-12 413999004663 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 143.9, E-value 2.9e-40 413999004664 Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124 413999004665 Cytochrome P450; Region: p450; cl12078 413999004666 Cytochrome P450; Region: p450; cl12078 413999004667 Pfam match to entry PF00067 p450, Cytochrome P450,score -36.2, E-value 3e-08 413999004668 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 413999004669 metal-binding site [ion binding] 413999004670 Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785 413999004671 Family description; Region: DsbD_2; pfam13386 413999004672 Cupredoxin-like domain; Region: Cupredoxin_1; cl17234 413999004673 Plastocyanin domain containing protein [General function prediction only]; Region: COG4633 413999004674 7 probable transmembrane helices predicted for CBO1039 by TMHMM2.0 at aa 77-99, 109-131, 152-174,184-206, 227-249, 259-281 and 293-315 413999004675 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 49.3, E-value 9e-12 413999004676 PS01047 Heavy-metal-associated domain. 413999004677 Predicted membrane protein [Function unknown]; Region: COG3462 413999004678 Short C-terminal domain; Region: SHOCT; pfam09851 413999004679 1 probable transmembrane helix predicted for CBO1040 by TMHMM2.0 at aa 15-37 413999004680 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999004681 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999004682 active site 413999004683 phosphorylation site [posttranslational modification] 413999004684 intermolecular recognition site; other site 413999004685 dimerization interface [polypeptide binding]; other site 413999004686 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999004687 DNA binding site [nucleotide binding] 413999004688 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 141.3, E-value 1.8e-39 413999004689 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 92.1, E-value 1.1e-24 413999004690 PS00230 Neuraxin and MAP1B proteins repeated region signature. 413999004691 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999004692 HAMP domain; Region: HAMP; pfam00672 413999004693 dimerization interface [polypeptide binding]; other site 413999004694 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999004695 dimer interface [polypeptide binding]; other site 413999004696 phosphorylation site [posttranslational modification] 413999004697 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999004698 ATP binding site [chemical binding]; other site 413999004699 Mg2+ binding site [ion binding]; other site 413999004700 G-X-G motif; other site 413999004701 2 probable transmembrane helices predicted for CBO1042 by TMHMM2.0 at aa 10-32 and 169-191 413999004702 Pfam match to entry PF00672 HAMP, HAMP domain,score 54.5, E-value 2.4e-13 413999004703 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 57.3, E-value 3.6e-14 413999004704 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 149.1, E-value 8.3e-42 413999004705 A new structural DNA glycosylase; Region: AlkD_like; cd06561 413999004706 active site 413999004707 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999004708 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999004709 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999004710 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 42.8, E-value 8.2e-10 413999004711 PS00041 Bacterial regulatory proteins, araC family signature. 413999004712 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 46.4, E-value 6.7e-11 413999004713 Predicted helix-turn-helix motif with score 996.000, SD 2.58 at aa 163-184, sequence ISLDDISRHLKINKSYFCSILK 413999004714 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 413999004715 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999004716 ABC-ATPase subunit interface; other site 413999004717 dimer interface [polypeptide binding]; other site 413999004718 putative PBP binding regions; other site 413999004719 8 probable transmembrane helices predicted for CBO1045 by TMHMM2.0 at aa 5-22, 42-64, 106-123, 133-155,182-204, 219-252, 264-286 and 291-310 413999004720 Pfam match to entry PF01032 FecCD, FecCD transport family, score 159.1, E-value 8.2e-45 413999004721 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999004722 ABC-ATPase subunit interface; other site 413999004723 dimer interface [polypeptide binding]; other site 413999004724 putative PBP binding regions; other site 413999004725 ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604 413999004726 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999004727 Walker A/P-loop; other site 413999004728 ATP binding site [chemical binding]; other site 413999004729 Q-loop/lid; other site 413999004730 ABC transporter signature motif; other site 413999004731 Walker B; other site 413999004732 D-loop; other site 413999004733 H-loop/switch region; other site 413999004734 Pfam match to entry PF00005 ABC_tran, ABC transporter score 176.6, E-value 4.4e-50 413999004735 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004736 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999004737 Siderophore binding protein FatB. These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140 413999004738 putative ligand binding residues [chemical binding]; other site 413999004739 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 193.4, E-value 3.8e-55 413999004740 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999004741 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999004742 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 20.7, E-value 0.0037 413999004743 PS00041 Bacterial regulatory proteins, araC family signature. 413999004744 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 47.2, E-value 3.9e-11 413999004745 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999004746 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999004747 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999004748 Walker A/P-loop; other site 413999004749 ATP binding site [chemical binding]; other site 413999004750 Q-loop/lid; other site 413999004751 ABC transporter signature motif; other site 413999004752 Walker B; other site 413999004753 D-loop; other site 413999004754 H-loop/switch region; other site 413999004755 5 probable transmembrane helices predicted for CBO1050 by TMHMM2.0 at aa 21-43, 66-88, 148-170, 255-277 and 284-301 413999004756 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 31.1, E-value 2.7e-06 413999004757 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.2, E-value 4.4e-55 413999004758 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004759 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999004760 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999004761 ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249 413999004762 Walker A/P-loop; other site 413999004763 ATP binding site [chemical binding]; other site 413999004764 Q-loop/lid; other site 413999004765 ABC transporter signature motif; other site 413999004766 Walker B; other site 413999004767 D-loop; other site 413999004768 H-loop/switch region; other site 413999004769 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 30.8, E-value 3.4e-06 413999004770 5 probable transmembrane helices predicted for CBO1051 by TMHMM2.0 at aa 22-44, 59-81, 136-158, 162-179 and 263-285 413999004771 Pfam match to entry PF00005 ABC_tran, ABC transporter score 249.1, E-value 6.3e-72 413999004772 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004773 PS00211 ABC transporters family signature. 413999004774 Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972 413999004775 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518 413999004776 ATP binding site [chemical binding]; other site 413999004777 Mg2+ binding site [ion binding]; other site 413999004778 G-X-G motif; other site 413999004779 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 17.2,E-value 0.0012 413999004780 6 probable transmembrane helices predicted for CBO1052 by TMHMM2.0 at aa 12-30, 65-87, 100-119, 129-151,171-190 and 205-227 413999004781 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 413999004782 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999004783 active site 413999004784 phosphorylation site [posttranslational modification] 413999004785 intermolecular recognition site; other site 413999004786 dimerization interface [polypeptide binding]; other site 413999004787 LytTr DNA-binding domain; Region: LytTR; smart00850 413999004788 Pfam match to entry PF04397 LytTR, LytTr DNA-binding domain, score 102.6, E-value 8.1e-28 413999004789 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 50.9, E-value 2.9e-12 413999004790 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 42.2, E-value 2.3e-11 413999004791 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 413999004792 conserved repeat domain; Region: B_ant_repeat; TIGR01451 413999004793 Domain of unknown function DUF11; Region: DUF11; pfam01345 413999004794 Domain of unknown function DUF11; Region: DUF11; cl17728 413999004795 Domain of unknown function DUF11; Region: DUF11; pfam01345 413999004796 Pfam match to entry PF01345 DUF11, Domain of unknown function DUF11, score 43.7, E-value 4.3e-10 413999004797 Pfam match to entry PF01345 DUF11, Domain of unknown function DUF11, score 45.9, E-value 9.2e-11 413999004798 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat, score 11.9, E-value 1.6 413999004799 Pfam match to entry PF01345 DUF11, Domain of unknown function DUF11, score 30.3, E-value 4.5e-06 413999004800 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat, score 9.4, E-value 5 413999004801 Pfam match to entry PF01345 DUF11, Domain of unknown function DUF11, score 51.3, E-value 2.2e-12 413999004802 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat, score 10.5, E-value 3.6 413999004803 Pfam match to entry PF01345 DUF11, Domain of unknown function DUF11, score 53.9, E-value 3.8e-13 413999004804 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat, score 6.1, E-value 13 413999004805 GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871 413999004806 Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704 413999004807 putative active site [active] 413999004808 Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063 413999004809 Interdomain contacts; other site 413999004810 Cytokine receptor motif; other site 413999004811 chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214 413999004812 1 probable transmembrane helix predicted for CBO1057 by TMHMM2.0 at aa 7-29 413999004813 Pfam match to entry PF00704 Glyco_hydro_18,Glycosyl hydrolases family 18, score 65.9, E-value 8.7e-17 413999004814 PS01095 Chitinases family 18 active site. 413999004815 Pfam match to entry PF00041 fn3, Fibronectin type III domain, score 12.6, E-value 0.0019 413999004816 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain, score 9.8, E-value 0.0085 413999004817 Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331 413999004818 TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955 413999004819 catalytic residues [active] 413999004820 AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183 413999004821 Pfam match to entry PF03190 DUF255, Protein of unknown function, DUF255, score 188.4, E-value 1.2e-53 413999004822 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 413999004823 Predicted membrane protein [Function unknown]; Region: COG4129 413999004824 Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081 413999004825 DUF939 C-terminal domain; Region: DUF939_C; pfam11728 413999004826 Pfam match to entry PF06081 DUF939, Bacterial protein of unknown function (DUF939), score 479.0, E-value 4e-141 413999004827 4 probable transmembrane helices predicted for CBO1059 by TMHMM2.0 at aa 20-42, 52-74, 79-101 and 116-138 413999004828 Predicted Ser/Thr protein kinase [Signal transduction mechanisms]; Region: COG2112 413999004829 CAAX protease self-immunity; Region: Abi; pfam02517 413999004830 7 probable transmembrane helices predicted for CBO1061 by TMHMM2.0 at aa 13-35, 39-61, 81-103, 123-145,158-175, 179-201 and 208-230 413999004831 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 27.2, E-value 4.1e-05 413999004832 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 413999004833 Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237 413999004834 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 29.5, E-value 8.4e-06 413999004835 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 413999004836 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999004837 Walker A/P-loop; other site 413999004838 ATP binding site [chemical binding]; other site 413999004839 Q-loop/lid; other site 413999004840 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999004841 ABC transporter signature motif; other site 413999004842 Walker B; other site 413999004843 ABC transporter; Region: ABC_tran_2; pfam12848 413999004844 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999004845 Pfam match to entry PF00005 ABC_tran, ABC transporter score 120.6, E-value 3e-33 413999004846 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004847 Pfam match to entry PF00005 ABC_tran, ABC transporter score 142.8, E-value 6.5e-40 413999004848 PS00211 ABC transporters family signature. 413999004849 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004850 Nucleoside recognition; Region: Gate; pfam07670 413999004851 8 probable transmembrane helices predicted for CBO1064 by TMHMM2.0 at aa 30-52, 72-94, 146-168, 178-200,251-273, 314-336, 343-365 and 380-402 413999004852 Arsenate Reductase (ArsC) family; composed of TRX-fold arsenic reductases and similar proteins including the transcriptional regulator, Spx. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from...; Region: ArsC_family; cd02977 413999004853 ArsC family; Region: ArsC; pfam03960 413999004854 catalytic residue [active] 413999004855 Pfam match to entry PF03960 ArsC, ArsC family,score 64.1, E-value 3.2e-16 413999004856 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999004857 FeS/SAM binding site; other site 413999004858 Domain of unknown function (DUF4008); Region: DUF4008; pfam13186 413999004859 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 21.1, E-value 1.3e-05 413999004860 Predicted dehydrogenase [General function prediction only]; Region: COG0579 413999004861 hydroxyglutarate oxidase; Provisional; Region: PRK11728 413999004862 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 413999004863 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase, score -16.8, E-value 1.5e-06 413999004864 Pfam match to entry PF04324 fer2_BFD, BFD-like [2Fe-2S] binding domain, score 95.7, E-value 9.4e-26 413999004865 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999004866 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 413999004867 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 108.3, E-value 1.6e-29 413999004868 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cd00368 413999004869 Protein of unknown function (DUF1667); Region: DUF1667; pfam07892 413999004870 glycerol-3-phosphate transporter; Region: glpT; TIGR00712 413999004871 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999004872 putative substrate translocation pore; other site 413999004873 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -88.7, E-value 0.00048 413999004874 12 probable transmembrane helices predicted for CBO1071 by TMHMM2.0 at aa 29-46, 66-88, 95-112, 117-139,160-182, 186-205, 251-273, 288-310, 319-337, 342-364,376-398 and 408-430 413999004875 PS00942 glpT family of transporters signature. 413999004876 arginyl-tRNA synthetase; Reviewed; Region: PRK12451 413999004877 Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016 413999004878 catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671 413999004879 active site 413999004880 HIGH motif; other site 413999004881 KMSK motif region; other site 413999004882 Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956 413999004883 tRNA binding surface [nucleotide binding]; other site 413999004884 anticodon binding site; other site 413999004885 Pfam match to entry PF03485 N-Arg, Arginyl tRNA synthetase N terminal domain, score 96.6, E-value 5.1e-26 413999004886 Pfam match to entry PF00750 tRNA-synt_1d, tRNA synthetases class I (R), score 331.6, E-value 9.4e-97 413999004887 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999004888 Pfam match to entry PF05746 tRNA-synt_1d_C, Arginyl tRNA synthetase anticodon binding domain, score 156.8,E-value 4e-44 413999004889 transaminase; Validated; Region: PRK07324 413999004890 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999004891 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999004892 homodimer interface [polypeptide binding]; other site 413999004893 catalytic residue [active] 413999004894 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 78.4, E-value 1.6e-20 413999004895 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 413999004896 FOG: CBS domain [General function prediction only]; Region: COG0517 413999004897 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205 413999004898 Pfam match to entry PF00571 CBS, CBS domain, score 61.4, E-value 2e-15 413999004899 Pfam match to entry PF00571 CBS, CBS domain, score 44.0, E-value 3.5e-10 413999004900 Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370 413999004901 Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879 413999004902 G1 box; other site 413999004903 GTP/Mg2+ binding site [chemical binding]; other site 413999004904 Switch I region; other site 413999004905 G2 box; other site 413999004906 G3 box; other site 413999004907 Switch II region; other site 413999004908 G4 box; other site 413999004909 G5 box; other site 413999004910 Nucleoside recognition; Region: Gate; pfam07670 413999004911 Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664 413999004912 Nucleoside recognition; Region: Gate; pfam07670 413999004913 9 probable transmembrane helices predicted for CBO1076 by TMHMM2.0 at aa 205-224, 272-294, 315-337,352-374, 381-400, 442-461, 495-517, 527-549 and 562-584 413999004914 Pfam match to entry PF02421 FeoB, Ferrous iron transport protein B, score 863.9, E-value 5.2e-257 413999004915 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004916 Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918 413999004917 Pfam match to entry PF04023 FeoA, FeoA family,score 68.9, E-value 1.2e-17 413999004918 PilZ domain; Region: PilZ; pfam07238 413999004919 haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702 413999004920 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999004921 motif II; other site 413999004922 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 5.9, E-value 0.0093 413999004923 PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543 413999004924 active site 413999004925 Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704 413999004926 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 413999004927 aromatic chitin/cellulose binding site residues [chemical binding]; other site 413999004928 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 413999004929 aromatic chitin/cellulose binding site residues [chemical binding]; other site 413999004930 Pfam match to entry PF00704 Glyco_hydro_18,Glycosyl hydrolases family 18, score -26.4, E-value 0.0039 413999004931 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain, score 47.9, E-value 2.4e-11 413999004932 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain, score 36.9, E-value 4.8e-08 413999004933 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 51.2, E-value 2.4e-12 413999004934 ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135 413999004935 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 413999004936 Walker A/P-loop; other site 413999004937 ATP binding site [chemical binding]; other site 413999004938 Q-loop/lid; other site 413999004939 ABC transporter signature motif; other site 413999004940 Walker B; other site 413999004941 D-loop; other site 413999004942 H-loop/switch region; other site 413999004943 NIL domain; Region: NIL; pfam09383 413999004944 Pfam match to entry PF00005 ABC_tran, ABC transporter score 244.6, E-value 1.4e-70 413999004945 PS00017 ATP/GTP-binding site motif A (P-loop). 413999004946 PS00211 ABC transporters family signature. 413999004947 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999004948 dimer interface [polypeptide binding]; other site 413999004949 conserved gate region; other site 413999004950 ABC-ATPase subunit interface; other site 413999004951 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 72.2, E-value 1.1e-18 413999004952 5 probable transmembrane helices predicted for CBO1085 by TMHMM2.0 at aa 15-37, 57-79, 83-105, 143-165 and 185-207 413999004953 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999004954 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 413999004955 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 413999004956 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999004957 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein, score 451.5, E-value 7.6e-133 413999004958 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 413999004959 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 413999004960 1 probable transmembrane helix predicted for CBO1087 by TMHMM2.0 at aa 5-27 413999004961 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999004962 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein, score 478.6, E-value 5.2e-141 413999004963 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 413999004964 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019 413999004965 metal binding site [ion binding]; metal-binding site 413999004966 putative dimer interface [polypeptide binding]; other site 413999004967 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 293.5, E-value 2.8e-85 413999004968 RNase_H superfamily; Region: RNase_H_2; pfam13482 413999004969 Transcriptional regulators [Transcription]; Region: FadR; COG2186 413999004970 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999004971 DNA-binding site [nucleotide binding]; DNA binding site 413999004972 FCD domain; Region: FCD; pfam07729 413999004973 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 85.9, E-value 8.3e-23 413999004974 PS00043 Bacterial regulatory proteins, gntR family signature. 413999004975 Predicted helix-turn-helix motif with score 987.000, SD 2.55 at aa 34-55, sequence PSERELVDQLKVSRTSIREALR 413999004976 Uncharacterized conserved protein [Function unknown]; Region: COG1284 413999004977 Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588 413999004978 Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588 413999004979 Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035 413999004980 Pfam match to entry PF02588 DUF161, Uncharacterized BCR, YitT family COG1284, score 95.4, E-value 1.2e-25 413999004981 5 probable transmembrane helices predicted for CBO1092 by TMHMM2.0 at aa 15-37, 44-66, 81-98, 110-129 and 154-176 413999004982 Pfam match to entry PF02588 DUF161, Uncharacterized BCR, YitT family COG1284, score 78.1, E-value 1.9e-20 413999004983 glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406 413999004984 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 413999004985 active site 413999004986 HIGH motif; other site 413999004987 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 413999004988 active site 413999004989 KMSKS motif; other site 413999004990 Pfam match to entry PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q), catalytic domain, score 482.7, E-value 3e-142 413999004991 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999004992 glyceraldehyde-3-phosphate dehydrogenase; Validated; Region: PRK07729 413999004993 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 413999004994 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 413999004995 Pfam match to entry PF00044 gpdh, Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain, score 295.4, E-value 7.1e-86 413999004996 PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 413999004997 Pfam match to entry PF02800 gpdh_C, Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, score 389.1,E-value 4.7e-114 413999004998 Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236 413999004999 Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446 413999005000 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999005001 Beta-Casp domain; Region: Beta-Casp; smart01027 413999005002 RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521 413999005003 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 64.2, E-value 2.9e-16 413999005004 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005005 1 probable transmembrane helix predicted for CBO1097 by TMHMM2.0 at aa 33-55 413999005006 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999005007 Zn2+ binding site [ion binding]; other site 413999005008 Mg2+ binding site [ion binding]; other site 413999005009 Pfam match to entry PF01966 HD, HD domain, score 41.1, E-value 2.6e-09 413999005010 aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381 413999005011 Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136 413999005012 NAD(P) binding site [chemical binding]; other site 413999005013 catalytic residues [active] 413999005014 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase, score 471.5, E-value 7e-139 413999005015 PS00687 Aldehyde dehydrogenases glutamic acid active site. 413999005016 PS00070 Aldehyde dehydrogenases cysteine active site. 413999005017 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999005018 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 413999005019 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 333.4, E-value 2.6e-97 413999005020 10 probable transmembrane helices predicted for CBO1100 by TMHMM2.0 at aa 13-35, 81-103, 145-167, 177-199,211-229, 239-261, 299-321, 352-374, 381-403 and 408-430 413999005021 PS00873 Sodium:alanine symporter family signature. 413999005022 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999005023 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 413999005024 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 357.7, E-value 1.3e-104 413999005025 9 probable transmembrane helices predicted for CBO1101 by TMHMM2.0 at aa 15-37, 83-105, 148-167, 180-202,212-232, 300-322, 353-375, 382-404 and 409-431 413999005026 PS00873 Sodium:alanine symporter family signature. 413999005027 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999005028 MarR family; Region: MarR_2; pfam12802 413999005029 Pfam match to entry PF01047 MarR, MarR family,score 74.2, E-value 2.8e-19 413999005030 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999005031 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 413999005032 12 probable transmembrane helices predicted for CBO1103 by TMHMM2.0 at aa 19-41, 61-83, 96-118, 138-155,168-190, 194-216, 236-258, 273-295, 320-339, 354-376,389-411 and 416-438 413999005033 Pfam match to entry PF01554 MatE, MatE, score 100.4, E-value 3.6e-27 413999005034 Pfam match to entry PF01554 MatE, MatE, score 79.9,E-value 5.6e-21 413999005035 Protein of unknown function (DUF2971); Region: DUF2971; pfam11185 413999005036 1 probable transmembrane helix predicted for CBO1106 by TMHMM2.0 at aa 10-29 413999005037 hypothetical protein; Provisional; Region: PRK11622 413999005038 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 413999005039 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005040 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005041 dimer interface [polypeptide binding]; other site 413999005042 conserved gate region; other site 413999005043 putative PBP binding loops; other site 413999005044 ABC-ATPase subunit interface; other site 413999005045 6 probable transmembrane helices predicted for CBO1108 by TMHMM2.0 at aa 7-29, 65-87, 100-122, 153-175,196-218 and 256-275 413999005046 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 35.7, E-value 1.1e-07 413999005047 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 413999005048 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005049 dimer interface [polypeptide binding]; other site 413999005050 conserved gate region; other site 413999005051 putative PBP binding loops; other site 413999005052 ABC-ATPase subunit interface; other site 413999005053 7 probable transmembrane helices predicted for CBO1109 by TMHMM2.0 at aa 7-29, 68-90, 102-124, 129-151,177-199, 204-226 and 233-252 413999005054 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 40.4, E-value 4.3e-09 413999005055 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 413999005056 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 413999005057 Walker A/P-loop; other site 413999005058 ATP binding site [chemical binding]; other site 413999005059 Q-loop/lid; other site 413999005060 ABC transporter signature motif; other site 413999005061 Walker B; other site 413999005062 D-loop; other site 413999005063 H-loop/switch region; other site 413999005064 Pfam match to entry PF00005 ABC_tran, ABC transporter score 226.2, E-value 5e-65 413999005065 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005066 PS00211 ABC transporters family signature. 413999005067 Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090 413999005068 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 413999005069 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999005070 Coenzyme A binding pocket [chemical binding]; other site 413999005071 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 58.5, E-value 1.6e-14 413999005072 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 413999005073 catalytic residues [active] 413999005074 3 probable transmembrane helices predicted for CBO1114 by TMHMM2.0 at aa 5-27, 39-58 and 73-92 413999005075 Membrane protein of unknown function (DUF340); Region: DUF340; pfam03956 413999005076 Pfam match to entry PF03956 DUF340, Membrane protein of unknown function (DUF340), score 155.3, E-value 1.1e-43 413999005077 6 probable transmembrane helices predicted for CBO1115 by TMHMM2.0 at aa 3-20, 24-43, 64-86, 96-113,118-140 and 173-195 413999005078 maltose O-acetyltransferase; Provisional; Region: PRK10092 413999005079 Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357 413999005080 active site 413999005081 substrate binding site [chemical binding]; other site 413999005082 trimer interface [polypeptide binding]; other site 413999005083 CoA binding site [chemical binding]; other site 413999005084 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 15.3,E-value 0.15 413999005085 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 14.5,E-value 0.26 413999005086 PS00101 Hexapeptide-repeat containing-transferases signature. 413999005087 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.3,E-value 5.1 413999005088 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886 413999005089 Biotin operon repressor [Transcription]; Region: BirA; COG1654 413999005090 Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057 413999005091 Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237 413999005092 Pfam match to entry PF02237 BPL_C, Biotin protein ligase C terminal domain, score 41.0, E-value 2.8e-09 413999005093 Pfam match to entry PF03099 BPL_LipA_LipB,Biotin/lipoate A/B protein ligase, score 132.6,E-value 7.5e-37 413999005094 Predicted helix-turn-helix motif with score 1636.000, SD 4.76 at aa 17-38, sequence ISGQYISDKLGVSRTAIWKYIN 413999005095 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 413999005096 metal-binding site [ion binding] 413999005097 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 15.2, E-value 0.026 413999005098 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643 413999005099 FOG: CBS domain [General function prediction only]; Region: COG0517 413999005100 Pfam match to entry PF00571 CBS, CBS domain, score 41.4, E-value 2.1e-09 413999005101 Pfam match to entry PF00571 CBS, CBS domain, score 7.0, E-value 0.51 413999005102 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999005103 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999005104 dimer interface [polypeptide binding]; other site 413999005105 phosphorylation site [posttranslational modification] 413999005106 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999005107 ATP binding site [chemical binding]; other site 413999005108 Mg2+ binding site [ion binding]; other site 413999005109 G-X-G motif; other site 413999005110 1 probable transmembrane helix predicted for CBO1120 by TMHMM2.0 at aa 20-39 413999005111 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 46.1, E-value 8e-11 413999005112 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 116.8, E-value 4.4e-32 413999005113 Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396 413999005114 nucleophile elbow; other site 413999005115 Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239 413999005116 MgtE intracellular N domain; Region: MgtE_N; smart00924 413999005117 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE. MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606 413999005118 Divalent cation transporter; Region: MgtE; pfam01769 413999005119 Pfam match to entry PF03448 MgtE_N, MgtE intracellular domain, score 112.6, E-value 8.1e-31 413999005120 Pfam match to entry PF00571 CBS, CBS domain, score 24.5, E-value 0.00026 413999005121 Pfam match to entry PF00571 CBS, CBS domain, score 47.7, E-value 2.8e-11 413999005122 Pfam match to entry PF01769 MgtE, Divalent cation transporter score 167.0, E-value 3.4e-47 413999005123 3 probable transmembrane helices predicted for CBO1124 by TMHMM2.0 at aa 363-382, 395-414 and 424-446 413999005124 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075 413999005125 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999005126 catalytic residue [active] 413999005127 Pfam match to entry PF00266 aminotran_5,Aminotransferase class-V, score 9.7, E-value 1.1e-10 413999005128 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 413999005129 Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303 413999005130 putative ligand binding site [chemical binding]; other site 413999005131 NAD binding site [chemical binding]; other site 413999005132 dimerization interface [polypeptide binding]; other site 413999005133 catalytic site [active] 413999005134 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain,score 111.2, E-value 2.1e-30 413999005135 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain,score 183.8, E-value 2.9e-52 413999005136 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005137 Protein of unknown function (DUF1015); Region: DUF1015; pfam06245 413999005138 Uncharacterized conserved protein [Function unknown]; Region: COG4198 413999005139 Pfam match to entry PF06245 DUF1015, Protein of unknown function (DUF1015), score 649.6, E-value 1.8e-192 413999005140 metallo-beta-lactamase/flavodoxin domain-containing protein; Provisional; Region: PRK11921 413999005141 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999005142 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 413999005143 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 96.7, E-value 4.9e-26 413999005144 Pfam match to entry PF00258 flavodoxin, Flavodoxin,score 53.6, E-value 4.4e-13 413999005145 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999005146 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924 413999005147 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999005148 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580 413999005149 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999005150 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581 413999005151 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 44.7, E-value 2.2e-10 413999005152 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 105.8, E-value 8.7e-29 413999005153 BCCT family transporter; Region: BCCT; pfam02028 413999005154 Pfam match to entry PF02028 BCCT, BCCT family transporter score 663.7, E-value 1e-196 413999005155 12 probable transmembrane helices predicted for CBO1131 by TMHMM2.0 at aa 11-33, 48-67, 86-108, 135-157,188-210, 225-247, 254-276, 310-329, 341-363, 390-412,436-453 and 458-480 413999005156 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 413999005157 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999005158 DNA-binding site [nucleotide binding]; DNA binding site 413999005159 TrkA-C domain; Region: TrkA_C; pfam02080 413999005160 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 25.0, E-value 0.00012 413999005161 Predicted helix-turn-helix motif with score 1536.000, SD 4.42 at aa 32-53, sequence RGRSTLSSKYNVSPETIRRAVS 413999005162 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 51.8, E-value 1.6e-12 413999005163 Flavin Reductases; Region: FlaRed; cl00801 413999005164 Isochorismatase family; Region: Isochorismatase; pfam00857 413999005165 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220 413999005166 catalytic triad [active] 413999005167 conserved cis-peptide bond; other site 413999005168 Pfam match to entry PF00857 Isochorismatase,Isochorismatase, score -27.9, E-value 2.9e-05 413999005169 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 413999005170 active site residue [active] 413999005171 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 57.7, E-value 2.7e-14 413999005172 Domain of unknown function (DUF4250); Region: DUF4250; pfam14056 413999005173 TPR repeat; Region: TPR_11; pfam13414 413999005174 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999005175 binding surface 413999005176 TPR motif; other site 413999005177 TPR repeat; Region: TPR_11; pfam13414 413999005178 TPR repeat; Region: TPR_11; pfam13414 413999005179 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999005180 binding surface 413999005181 TPR motif; other site 413999005182 TPR repeat; Region: TPR_11; pfam13414 413999005183 Pfam match to entry PF00515 TPR, TPR Domain, score 28.4, E-value 1.7e-05 413999005184 Pfam match to entry PF00515 TPR, TPR Domain, score 36.5, E-value 6.5e-08 413999005185 Pfam match to entry PF00515 TPR, TPR Domain, score 31.1, E-value 2.7e-06 413999005186 Pfam match to entry PF00515 TPR, TPR Domain, score 13.6, E-value 0.09 413999005187 Pfam match to entry PF00515 TPR, TPR Domain, score 21.2, E-value 0.0026 413999005188 Pfam match to entry PF00515 TPR, TPR Domain, score 13.4, E-value 0.095 413999005189 Pfam match to entry PF00515 TPR, TPR Domain, score 29.3, E-value 9.5e-06 413999005190 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999005191 active site 413999005192 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 51.5, E-value 2e-12 413999005193 Protein of unknown function (DUF3867); Region: DUF3867; pfam12983 413999005194 Rhodanese Homology Domain; Region: RHOD; smart00450 413999005195 active site residue [active] 413999005196 Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897 413999005197 Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448 413999005198 active site residue [active] 413999005199 Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449 413999005200 active site residue [active] 413999005201 1 probable transmembrane helix predicted for CBO1141 by TMHMM2.0 at aa 7-24 413999005202 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005203 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 29.1, E-value 1.1e-05 413999005204 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 46.5, E-value 6.3e-11 413999005205 4 probable transmembrane helices predicted for CBO1142 by TMHMM2.0 at aa 7-26, 57-79, 86-105 and 115-137 413999005206 Domain of unknown function DUF20; Region: UPF0118; pfam01594 413999005207 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 413999005208 8 probable transmembrane helices predicted for CBO1143 by TMHMM2.0 at aa 7-29, 44-63, 76-98, 169-191,229-251, 256-278, 283-305 and 325-347 413999005209 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20, score 230.8, E-value 2.1e-66 413999005210 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541 413999005211 putative metal binding site [ion binding]; other site 413999005212 Pfam match to entry PF03819 MazG, MazG nucleotide pyrophosphohydrolase domain, score 62.0, E-value 1.4e-15 413999005213 Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270 413999005214 Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270 413999005215 active site 413999005216 metal-binding site [ion binding] 413999005217 nucleotide-binding site [chemical binding]; other site 413999005218 nucleotide-binding site [chemical binding]; other site 413999005219 PS00092 N-6 Adenine-specific DNA methylases signature. 413999005220 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005221 1 probable transmembrane helix predicted for CBO1148 by TMHMM2.0 at aa 7-29 413999005222 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 413999005223 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 413999005224 Walker A/P-loop; other site 413999005225 ATP binding site [chemical binding]; other site 413999005226 Q-loop/lid; other site 413999005227 ABC transporter signature motif; other site 413999005228 Walker B; other site 413999005229 D-loop; other site 413999005230 H-loop/switch region; other site 413999005231 Pfam match to entry PF00005 ABC_tran, ABC transporter score 227.0, E-value 2.8e-65 413999005232 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005233 PS00211 ABC transporters family signature. 413999005234 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005235 dimer interface [polypeptide binding]; other site 413999005236 conserved gate region; other site 413999005237 putative PBP binding loops; other site 413999005238 ABC-ATPase subunit interface; other site 413999005239 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 86.5, E-value 5.7e-23 413999005240 5 probable transmembrane helices predicted for CBO1150 by TMHMM2.0 at aa 20-42, 54-76, 81-103, 138-160 and 184-206 413999005241 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 413999005242 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 413999005243 substrate binding pocket [chemical binding]; other site 413999005244 membrane-bound complex binding site; other site 413999005245 hinge residues; other site 413999005246 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005247 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, score 167.1, E-value 3.2e-47 413999005248 PS00213 Lipocalin signature. 413999005249 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 413999005250 M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886 413999005251 metal binding site [ion binding]; metal-binding site 413999005252 dimer interface [polypeptide binding]; other site 413999005253 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 282.8, E-value 4.7e-82 413999005254 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 413999005255 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 413999005256 1 probable transmembrane helix predicted for CBO1153 by TMHMM2.0 at aa 7-24 413999005257 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 68.3, E-value 1.8e-17 413999005258 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005259 putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262 413999005260 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005261 dimer interface [polypeptide binding]; other site 413999005262 conserved gate region; other site 413999005263 putative PBP binding loops; other site 413999005264 ABC-ATPase subunit interface; other site 413999005265 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005266 dimer interface [polypeptide binding]; other site 413999005267 conserved gate region; other site 413999005268 putative PBP binding loops; other site 413999005269 ABC-ATPase subunit interface; other site 413999005270 12 probable transmembrane helices predicted for CBO1154 by TMHMM2.0 at aa 23-45, 71-93, 108-130, 151-173,193-215, 222-244, 249-271, 305-327, 355-377, 390-412,479-501 and 521-543 413999005271 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 28.1, E-value 2.1e-05 413999005272 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 46.8, E-value 5e-11 413999005273 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999005274 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 413999005275 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999005276 Walker A/P-loop; other site 413999005277 ATP binding site [chemical binding]; other site 413999005278 Q-loop/lid; other site 413999005279 ABC transporter signature motif; other site 413999005280 Walker B; other site 413999005281 D-loop; other site 413999005282 H-loop/switch region; other site 413999005283 TOBE domain; Region: TOBE_2; pfam08402 413999005284 Pfam match to entry PF00005 ABC_tran, ABC transporter score 227.2, E-value 2.4e-65 413999005285 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005286 PS00211 ABC transporters family signature. 413999005287 zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240 413999005288 Double zinc ribbon; Region: DZR; pfam12773 413999005289 5 probable transmembrane helices predicted for CBO1156 by TMHMM2.0 at aa 68-90, 135-157, 170-192, 196-218 and 231-248 413999005290 zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240 413999005291 Double zinc ribbon; Region: DZR; pfam12773 413999005292 YARHG domain; Region: YARHG; pfam13308 413999005293 1 probable transmembrane helix predicted for CBO1157 by TMHMM2.0 at aa 117-136 413999005294 30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676 413999005295 S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687 413999005296 RNA binding site [nucleotide binding]; other site 413999005297 S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465 413999005298 RNA binding site [nucleotide binding]; other site 413999005299 S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688 413999005300 RNA binding site [nucleotide binding]; other site 413999005301 S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692 413999005302 RNA binding site [nucleotide binding]; other site 413999005303 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 28.7, E-value 1.4e-05 413999005304 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 34.8, E-value 2.1e-07 413999005305 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 109.0, E-value 9.8e-30 413999005306 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 109.0, E-value 9.7e-30 413999005307 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 413999005308 active site 413999005309 Pfam match to entry PF03061 4HBT, Thioesterase superfamily, score 44.0, E-value 3.4e-10 413999005310 Histidine Utilizing Protein, the hut operon positive regulatory protein; Region: HutP; cd11640 413999005311 hexamer interface [polypeptide binding]; other site 413999005312 RNA binding site [nucleotide binding]; other site 413999005313 Histidine-zinc binding site [chemical binding]; other site 413999005314 Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325 413999005315 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 413999005316 zinc binding site [ion binding]; other site 413999005317 putative ligand binding site [chemical binding]; other site 413999005318 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005319 Pfam match to entry PF04392 DUF534, Protein of unknown function (DUF534), score 313.6, E-value 2.5e-91 413999005320 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 413999005321 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574 413999005322 TM-ABC transporter signature motif; other site 413999005323 8 probable transmembrane helices predicted for CBO1163 by TMHMM2.0 at aa 3-25, 57-79, 86-105, 125-143,173-195, 199-221, 232-254 and 258-275 413999005324 Pfam match to entry PF02653 BPD_transp_2,Branched-chain amino acid transport system / permease component, score 89.7, E-value 6.1e-24 413999005325 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101 413999005326 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999005327 Walker A/P-loop; other site 413999005328 ATP binding site [chemical binding]; other site 413999005329 Q-loop/lid; other site 413999005330 ABC transporter signature motif; other site 413999005331 Walker B; other site 413999005332 D-loop; other site 413999005333 H-loop/switch region; other site 413999005334 Pfam match to entry PF00005 ABC_tran, ABC transporter score 178.3, E-value 1.3e-50 413999005335 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005336 PS00211 ABC transporters family signature. 413999005337 3 probable transmembrane helices predicted for CBO1165 by TMHMM2.0 at aa 4-26, 46-68 and 78-95 413999005338 aspartate 4-decarboxylase; Region: asp_4_decarbox; TIGR03801 413999005339 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999005340 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999005341 homodimer interface [polypeptide binding]; other site 413999005342 catalytic residue [active] 413999005343 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 49.7, E-value 9.8e-14 413999005344 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 413999005345 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 413999005346 EamA-like transporter family; Region: EamA; pfam00892 413999005347 EamA-like transporter family; Region: EamA; pfam00892 413999005348 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 114.4, E-value 2.3e-31 413999005349 10 probable transmembrane helices predicted for CBO1167 by TMHMM2.0 at aa 7-24, 34-54, 67-86, 99-116,123-145, 155-172, 185-203, 213-235, 248-267 and 271-288 413999005350 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 112.9, E-value 6.3e-31 413999005351 putative kinase; Provisional; Region: PRK09954 413999005352 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 413999005353 YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941 413999005354 substrate binding site [chemical binding]; other site 413999005355 ATP binding site [chemical binding]; other site 413999005356 Predicted helix-turn-helix motif with score 1923.000, SD 5.74 at aa 18-39, sequence ISQKDLAEKLGITRSSAAVHIT 413999005357 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 143.3, E-value 4.5e-40 413999005358 Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227 413999005359 Pfam match to entry PF04227 Indigoidine_A,Indigoidine synthase A like protein, score 664.9, E-value 4.2e-197 413999005360 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 413999005361 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 413999005362 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 413999005363 Pfam match to entry PF02558 ApbA, Ketopantoate reductase PanE/ApbA, score 204.8, E-value 1.4e-58 413999005364 Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961 413999005365 Pfam match to entry PF04961 FTCD_C,Formiminotransferase-cyclodeaminase, score 87.1, E-value 3.6e-23 413999005366 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190 413999005367 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763 413999005368 NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080 413999005369 homodimer interface [polypeptide binding]; other site 413999005370 NADP binding site [chemical binding]; other site 413999005371 substrate binding site [chemical binding]; other site 413999005372 Pfam match to entry PF00763 THF_DHG_CYH,Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, score 91.6, E-value 1.7e-24 413999005373 Pfam match to entry PF02882 THF_DHG_CYH_C,Tetrahydrofolate dehydrogenase/cyclohydrolase,NAD(P)-binding domain, score 268.1, E-value 1.2e-77 413999005374 haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282 413999005375 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999005376 active site 413999005377 motif I; other site 413999005378 motif II; other site 413999005379 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 413999005380 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 19.3, E-value 0.00069 413999005381 PS01228 Hypothetical cof family signature 1. 413999005382 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999005383 Coenzyme A binding pocket [chemical binding]; other site 413999005384 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 56.5, E-value 5.9e-14 413999005385 8 probable transmembrane helices predicted for CBO1176 by TMHMM2.0 at aa 9-31, 46-65, 72-91, 96-113,126-148, 153-175, 188-210 and 225-244 413999005386 Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428 413999005387 ZIP Zinc transporter; Region: Zip; pfam02535 413999005388 Pfam match to entry PF02535 Zip, ZIP Zinc transporter score 100.4, E-value 3.8e-27 413999005389 5 probable transmembrane helices predicted for CBO1177 by TMHMM2.0 at aa 15-34, 41-60, 75-94, 212-234 and 249-268 413999005390 Predicted transcriptional regulator [Transcription]; Region: COG1959 413999005391 Transcriptional regulator; Region: Rrf2; cl17282 413999005392 Pfam match to entry PF02082 Rrf2, Transcriptional regulator, score 124.2, E-value 2.5e-34 413999005393 Predicted helix-turn-helix motif with score 1260.000, SD 3.48 at aa 26-47, sequence VTLKSISERQNISEGYLEQIFS 413999005394 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 413999005395 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 413999005396 dimer interface [polypeptide binding]; other site 413999005397 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999005398 catalytic residue [active] 413999005399 Pfam match to entry PF00291 PALP,Pyridoxal-phosphate dependent enzyme, score 426.8, E-value 2e-125 413999005400 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 413999005401 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 413999005402 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005403 dimer interface [polypeptide binding]; other site 413999005404 conserved gate region; other site 413999005405 putative PBP binding loops; other site 413999005406 ABC-ATPase subunit interface; other site 413999005407 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 117.7, E-value 2.2e-32 413999005408 4 probable transmembrane helices predicted for CBO1180 by TMHMM2.0 at aa 22-44, 57-79, 89-111 and 189-211 413999005409 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999005410 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 413999005411 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 413999005412 substrate binding pocket [chemical binding]; other site 413999005413 membrane-bound complex binding site; other site 413999005414 hinge residues; other site 413999005415 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005416 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, score 244.5, E-value 1.6e-70 413999005417 PS01034 Glycosyl hydrolases family 16 active sites. 413999005418 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 413999005419 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 413999005420 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999005421 catalytic residue [active] 413999005422 Pfam match to entry PF00266 aminotran_5,Aminotransferase class-V, score 350.9, E-value 1.4e-102 413999005423 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 413999005424 ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606 413999005425 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_I; cd01990 413999005426 Ligand Binding Site [chemical binding]; other site 413999005427 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482 413999005428 tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998 413999005429 Ligand Binding Site [chemical binding]; other site 413999005430 Pfam match to entry PF03054 tRNA_Me_trans, tRNA methyl transferase, score 558.6, E-value 4.2e-165 413999005431 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 413999005432 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999005433 active site 413999005434 phosphorylation site [posttranslational modification] 413999005435 intermolecular recognition site; other site 413999005436 LytTr DNA-binding domain; Region: LytTR; pfam04397 413999005437 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 52.1, E-value 1.2e-12 413999005438 Pfam match to entry PF04397 LytTR, LytTr DNA-binding domain, score 117.0, E-value 3.8e-32 413999005439 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999005440 ATP binding site [chemical binding]; other site 413999005441 Mg2+ binding site [ion binding]; other site 413999005442 G-X-G motif; other site 413999005443 6 probable transmembrane helices predicted for CBO1187 by TMHMM2.0 at aa 9-31, 46-68, 88-110, 120-142,162-184 and 194-216 413999005444 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 24.0,E-value 0.00021 413999005445 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999005446 ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268 413999005447 Walker A/P-loop; other site 413999005448 ATP binding site [chemical binding]; other site 413999005449 Q-loop/lid; other site 413999005450 ABC transporter signature motif; other site 413999005451 Walker B; other site 413999005452 D-loop; other site 413999005453 H-loop/switch region; other site 413999005454 Pfam match to entry PF00005 ABC_tran, ABC transporter score 179.0, E-value 8.3e-51 413999005455 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005456 PS00211 ABC transporters family signature. 413999005457 ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866 413999005458 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999005459 6 probable transmembrane helices predicted for CBO1189 by TMHMM2.0 at aa 13-35, 50-72, 104-126, 146-168,175-197 and 217-239 413999005460 Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; pfam10110 413999005461 Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615 413999005462 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 413999005463 active site 413999005464 catalytic site [active] 413999005465 7 probable transmembrane helices predicted for CBO1190 by TMHMM2.0 at aa 30-52, 77-99, 136-158, 182-204,238-260, 280-302 and 343-365 413999005466 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase, score 141.1, E-value 2.1e-39 413999005467 Domain of unknown function (DUF3787); Region: DUF3787; pfam12655 413999005468 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176 413999005469 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 413999005470 dimer interface [polypeptide binding]; other site 413999005471 PYR/PP interface [polypeptide binding]; other site 413999005472 TPP binding site [chemical binding]; other site 413999005473 substrate binding site [chemical binding]; other site 413999005474 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014 413999005475 Domain of unknown function; Region: EKR; pfam10371 413999005476 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999005477 Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377 413999005478 TPP-binding site [chemical binding]; other site 413999005479 dimer interface [polypeptide binding]; other site 413999005480 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 21.5, E-value 0.0001 413999005481 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999005482 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 25.4, E-value 2.5e-05 413999005483 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999005484 Pfam match to entry PF01558 POR, Pyruvate ferredoxin/flavodoxin oxidoreductase, score 282.3, E-value 6.3e-82 413999005485 Pfam match to entry PF01855 POR_N, Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain, score 400.4, E-value 1.9e-117 413999005486 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999005487 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999005488 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 43.2, E-value 6.3e-10 413999005489 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 413999005490 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 413999005491 13 probable transmembrane helices predicted for CBO1194 by TMHMM2.0 at aa 4-26, 33-50, 60-82, 95-117,122-144, 157-179, 189-211, 224-241, 251-270, 277-299,309-331, 344-366 and 376-395 413999005492 Pfam match to entry PF00999 Na_H_Exchanger,Sodium/hydrogen exchanger family, score 20.7, E-value 1.2e-05 413999005493 Uncharacterized conserved protein [Function unknown]; Region: COG0397 413999005494 hypothetical protein; Validated; Region: PRK00029 413999005495 Pfam match to entry PF02696 UPF0061,Uncharacterized ACR, YdiU/UPF0061 family, score 278.9,E-value 6.9e-81 413999005496 Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231 413999005497 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999005498 Pfam match to entry PF01593 Amino_oxidase, Flavin containing amine oxidoreductase, score 90.6, E-value 3.4e-24 413999005499 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 413999005500 Helix-turn-helix domain; Region: HTH_18; pfam12833 413999005501 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999005502 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 36.2, E-value 7.9e-08 413999005503 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 21.3, E-value 0.0025 413999005504 Predicted helix-turn-helix motif with score 1248.000, SD 3.44 at aa 207-228, sequence LTIKYIANQLNISTGYLLVNFK 413999005505 Pfam match to entry PF02311 AraC_binding, AraC-like ligand binding domain, score 15.3, E-value 0.0025 413999005506 melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392 413999005507 MFS/sugar transport protein; Region: MFS_2; pfam13347 413999005508 melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392 413999005509 6 probable transmembrane helices predicted for CBO1199 by TMHMM2.0 at aa 25-47, 57-79, 92-114, 118-140,161-183 and 198-220 413999005510 O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055 413999005511 Pfam match to entry PF02055 Glyco_hydro_30,O-Glycosyl hydrolase 30, score 57.8, E-value 2.5e-14 413999005512 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 413999005513 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 413999005514 nucleotide binding site [chemical binding]; other site 413999005515 Pfam match to entry PF00480 ROK, ROK family, score 96.0, E-value 7.6e-26 413999005516 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005517 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723 413999005518 beta-galactosidase; Region: BGL; TIGR03356 413999005519 Pfam match to entry PF00232 Glyco_hydro_1, Glycosyl hydrolase 1, score 536.9, E-value 1.5e-158 413999005520 PS00653 Glycosyl hydrolases family 1 N-terminal signature. 413999005521 PS00572 Glycosyl hydrolases family 1 active site. 413999005522 Glycosyl hydrolase family 14; Region: Glyco_hydro_14; cl03185 413999005523 Beta-amylase, C-terminal CBM20 (carbohydrate-binding module, family 20) domain. Beta-amylase has, in addition to its C-terminal CBM20 domain, an N-terminal catalytic domain belonging to glycosyl hydrolase family 14, which hydrolyzes the alpha-1; Region: CBM20_beta_amylase; cd05809 413999005524 starch-binding site 2 [chemical binding]; other site 413999005525 starch-binding site 1 [chemical binding]; other site 413999005526 Pfam match to entry PF01373 Glyco_hydro_14,Glycosyl hydrolase 14, score 873.2, E-value 8.7e-260 413999005527 Pfam match to entry PF00686 CBM_20, Starch binding domain, score 47.2, E-value 3.8e-11 413999005528 tyrosyl-tRNA synthetase; Provisional; Region: PRK13354 413999005529 catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805 413999005530 active site 413999005531 HIGH motif; other site 413999005532 dimer interface [polypeptide binding]; other site 413999005533 KMSKS motif; other site 413999005534 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999005535 RNA binding surface [nucleotide binding]; other site 413999005536 Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y), score 346.5, E-value 3.1e-101 413999005537 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999005538 Pfam match to entry PF01479 S4, S4 domain, score 47.6, E-value 2.9e-11 413999005539 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999005540 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999005541 DNA-binding site [nucleotide binding]; DNA binding site 413999005542 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 32.0, E-value 1.5e-06 413999005543 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999005544 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999005545 Walker A/P-loop; other site 413999005546 ATP binding site [chemical binding]; other site 413999005547 Q-loop/lid; other site 413999005548 ABC transporter signature motif; other site 413999005549 Walker B; other site 413999005550 D-loop; other site 413999005551 H-loop/switch region; other site 413999005552 Pfam match to entry PF00005 ABC_tran, ABC transporter score 103.0, E-value 6.3e-28 413999005553 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005554 6 probable transmembrane helices predicted for CBO1207 by TMHMM2.0 at aa 20-39, 49-71, 83-105, 149-171,176-198 and 218-240 413999005555 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999005556 Predicted glycosyl hydrolase [General function prediction only]; Region: COG3858 413999005557 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999005558 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999005559 Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the...; Region: GH18_CFLE_spore_hydrolase; cd02874 413999005560 active site 413999005561 Pfam match to entry PF01476 LysM, LysM domain,score 78.1, E-value 2e-20 413999005562 Pfam match to entry PF01476 LysM, LysM domain,score 68.0, E-value 2.1e-17 413999005563 Pfam match to entry PF00704 Glyco_hydro_18,Glycosyl hydrolases family 18, score 58.3, E-value 1.7e-14 413999005564 PS01095 Chitinases family 18 active site. 413999005565 PAS domain S-box; Region: sensory_box; TIGR00229 413999005566 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999005567 putative active site [active] 413999005568 heme pocket [chemical binding]; other site 413999005569 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999005570 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999005571 metal binding site [ion binding]; metal-binding site 413999005572 active site 413999005573 I-site; other site 413999005574 Pfam match to entry PF00989 PAS, PAS domain, score 34.8, E-value 2.1e-07 413999005575 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 215.8, E-value 6.8e-62 413999005576 L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719 413999005577 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 413999005578 ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141 413999005579 Pfam match to entry PF03315 SDH_beta, Serine dehydratase beta chain, score 207.0, E-value 3e-59 413999005580 Pfam match to entry PF01842 ACT, ACT domain, score 41.0, E-value 2.7e-09 413999005581 Serine dehydratase alpha chain; Region: SDH_alpha; cl12120 413999005582 L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760 413999005583 Pfam match to entry PF03313 SDH_alpha, Serine dehydratase alpha chain, score 342.5, E-value 4.8e-100 413999005584 1 probable transmembrane helix predicted for CBO1218 by TMHMM2.0 at aa 13-35 413999005585 Uncharacterized conserved protein [Function unknown]; Region: COG5663 413999005586 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 5.4, E-value 0.01 413999005587 Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355 413999005588 renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301 413999005589 active site 413999005590 dimer interface [polypeptide binding]; other site 413999005591 Pfam match to entry PF01244 Renal_dipeptase, Renal dipeptidase, score -4.0, E-value 1.9e-08 413999005592 4 probable transmembrane helices predicted for CBO1221 by TMHMM2.0 at aa 13-35, 45-67, 87-109 and 119-141 413999005593 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005594 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999005595 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 413999005596 FtsX-like permease family; Region: FtsX; pfam02687 413999005597 Pfam match to entry PF02687 FtsX, Predicted permease, score 135.9, E-value 7.6e-38 413999005598 4 probable transmembrane helices predicted for CBO1222 by TMHMM2.0 at aa 4-21, 263-285, 321-343 and 363-385 413999005599 S-layer domain [Cell envelope biogenesis, outer membrane]; Region: COG1361 413999005600 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999005601 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999005602 Walker A/P-loop; other site 413999005603 ATP binding site [chemical binding]; other site 413999005604 Q-loop/lid; other site 413999005605 ABC transporter signature motif; other site 413999005606 Walker B; other site 413999005607 D-loop; other site 413999005608 H-loop/switch region; other site 413999005609 Pfam match to entry PF00005 ABC_tran, ABC transporter score 217.6, E-value 1.9e-62 413999005610 PS00211 ABC transporters family signature. 413999005611 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005612 nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790 413999005613 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005614 dimer interface [polypeptide binding]; other site 413999005615 conserved gate region; other site 413999005616 putative PBP binding loops; other site 413999005617 ABC-ATPase subunit interface; other site 413999005618 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 162.0, E-value 1.1e-45 413999005619 6 probable transmembrane helices predicted for CBO1225 by TMHMM2.0 at aa 21-43, 89-111, 118-140, 145-167,196-218 and 253-275 413999005620 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 413999005621 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999005622 dimer interface [polypeptide binding]; other site 413999005623 conserved gate region; other site 413999005624 putative PBP binding loops; other site 413999005625 ABC-ATPase subunit interface; other site 413999005626 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 196.0, E-value 6.1e-56 413999005627 6 probable transmembrane helices predicted for CBO1226 by TMHMM2.0 at aa 13-35, 98-120, 133-155, 175-197,236-258 and 278-300 413999005628 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 413999005629 The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995 413999005630 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, score 289.6, E-value 4.1e-84 413999005631 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 413999005632 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005633 Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007 413999005634 CotJB protein; Region: CotJB; pfam12652 413999005635 Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051 413999005636 dimanganese center [ion binding]; other site 413999005637 Pfam match to entry PF05067 Mn_catalase, Manganese containing catalase, score 172.9, E-value 5.6e-49 413999005638 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: EpsL; COG4632 413999005639 1 probable transmembrane helix predicted for CBO1231 by TMHMM2.0 at aa 2-21 413999005640 Tubby C 2; Region: Tub_2; cl02043 413999005641 Pfam match to entry PF04525 DUF567, Protein of unknown function (DUF567), score 42.7, E-value 8.4e-10 413999005642 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 413999005643 trimer interface [polypeptide binding]; other site 413999005644 active site 413999005645 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cl00493 413999005646 Pfam match to entry PF00692 dUTPase, dUTPase, score 19.8, E-value 5.5e-05 413999005647 Pfam match to entry PF00692 dUTPase, dUTPase, score 18.2, E-value 0.00019 413999005648 small acid-soluble spore protein, H-type; Region: SASP_H; TIGR02861 413999005649 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005650 1 probable transmembrane helix predicted for CBO1238 by TMHMM2.0 at aa 39-61 413999005651 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999005652 non-specific DNA binding site [nucleotide binding]; other site 413999005653 salt bridge; other site 413999005654 sequence-specific DNA binding site [nucleotide binding]; other site 413999005655 Cupin domain; Region: Cupin_2; pfam07883 413999005656 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 58.4, E-value 1.6e-14 413999005657 Predicted helix-turn-helix motif with score 1685.000, SD 4.93 at aa 16-37, sequence LTIKELSELTNLSIGFISNLER 413999005658 Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303 413999005659 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425 413999005660 8 probable transmembrane helices predicted for CBO1241 by TMHMM2.0 at aa 2-21, 64-86, 98-120, 130-152,173-195, 205-224, 254-276 and 302-324 413999005661 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999005662 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999005663 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 25.9, E-value 0.0001 413999005664 1 probable transmembrane helix predicted for CBO1244 by TMHMM2.0 at aa 57-79 413999005665 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999005666 amino acid carrier protein; Region: agcS; TIGR00835 413999005667 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 721.7, E-value 3.4e-214 413999005668 9 probable transmembrane helices predicted for CBO1245 by TMHMM2.0 at aa 15-33, 86-108, 150-169, 182-204,214-233, 304-326, 346-368, 388-410 and 415-437 413999005669 PS00873 Sodium:alanine symporter family signature. 413999005670 PS00904 Protein prenyltransferases alpha subunit repeat signature. 413999005671 Low GC content region (22.21). Doubful CDSs within this feature 413999005672 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999005673 non-specific DNA binding site [nucleotide binding]; other site 413999005674 salt bridge; other site 413999005675 sequence-specific DNA binding site [nucleotide binding]; other site 413999005676 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 40.9, E-value 3.1e-09 413999005677 Predicted helix-turn-helix motif with score 1435.000, SD 4.07 at aa 23-44, sequence KTQKEFAEFLGIRRVQYNKYEN 413999005678 Helix-turn-helix domain; Region: HTH_17; pfam12728 413999005679 Predicted helix-turn-helix motif with score 1297.000, SD 3.60 at aa 33-54, sequence LTPQEFAQECELSYQQVLQMCK 413999005680 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999005681 NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976 413999005682 catalytic residues [active] 413999005683 Pfam match to entry PF00462 glutaredoxin,Glutaredoxin, score 30.1, E-value 5.2e-06 413999005684 PS00195 Glutaredoxin active site. 413999005685 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PLN00412 413999005686 NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082 413999005687 tetrameric interface [polypeptide binding]; other site 413999005688 activator binding site; other site 413999005689 NADP binding site [chemical binding]; other site 413999005690 substrate binding site [chemical binding]; other site 413999005691 catalytic residues [active] 413999005692 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase, score 577.3, E-value 1e-170 413999005693 PS00070 Aldehyde dehydrogenases cysteine active site. 413999005694 PS00687 Aldehyde dehydrogenases glutamic acid active site. 413999005695 thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292 413999005696 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999005697 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 206.5, E-value 4.3e-59 413999005698 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 413999005699 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005700 1 probable transmembrane helix predicted for CBO1254 by TMHMM2.0 at aa 7-29 413999005701 Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338 413999005702 glycine reductase, selenoprotein B; Region: gly_red_sel_B; TIGR01917 413999005703 selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family; Region: various_sel_PB; TIGR01918 413999005704 thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292 413999005705 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999005706 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999005707 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 249.6, E-value 4.5e-72 413999005708 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 413999005709 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 413999005710 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 413999005711 catalytic residues [active] 413999005712 Pfam match to entry PF00085 thiored, Thioredoxin,score 60.5, E-value 3.7e-15 413999005713 PS00194 Thioredoxin family active site. 413999005714 glycine/sarcosine/betaine reductase complex protein A; Reviewed; Region: PRK13265 413999005715 Pfam match to entry PF04723 GRDA, Glycine reductase complex selenoprotein A, score 82.8, E-value 1.1e-22 413999005716 Pfam match to entry PF04723 GRDA, Glycine reductase complex selenoprotein A, score 153.4, E-value 4.2e-43 413999005717 "initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827 413999005718 dimer interface [polypeptide binding]; other site 413999005719 active site 413999005720 Fatty acid synthesis protein; Region: FA_synthesis; cl17261 413999005721 Pfam match to entry PF02504 FA_synthesis, Fatty acid synthesis protein, score 235.5, E-value 7.9e-68 413999005722 Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540 413999005723 active site 413999005724 DNA binding site [nucleotide binding] 413999005725 Pfam match to entry PF02245 Pur_DNA_glyco,Methylpurine-DNA glycosylase (MPG), score 232.8, E-value 5.3e-67 413999005726 Eco57I restriction-modification methylase; Region: Eco57I; pfam07669 413999005727 TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950 413999005728 PS00092 N-6 Adenine-specific DNA methylases signature. 413999005729 methylthioribose kinase; Reviewed; Region: mtnK; PRK09550 413999005730 methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720 413999005731 S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512 413999005732 Pfam match to entry PF01008 IF-2B, Initiation factor 2 subunit family, score 368.3, E-value 8.2e-108 413999005733 Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596 413999005734 intersubunit interface [polypeptide binding]; other site 413999005735 active site 413999005736 Zn2+ binding site [ion binding]; other site 413999005737 Pfam match to entry PF00596 Aldolase_II, Class II Aldolase and Adducin N-terminal domain, score 149.9,E-value 4.6e-42 413999005738 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 413999005739 helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420 413999005740 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 413999005741 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family, score 217.1, E-value 2.8e-62 413999005742 PS00894 Bacterial regulatory proteins, deoR family signature. 413999005743 Predicted helix-turn-helix motif with score 1402.000, SD 3.96 at aa 22-43, sequence VDIMELSEKLQVSEMTIRRDLK 413999005744 Protein of unknown function (DUF1049); Region: DUF1049; cl01539 413999005745 2 probable transmembrane helices predicted for CBO1273 by TMHMM2.0 at aa 5-27 and 37-59 413999005746 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 413999005747 cation diffusion facilitator family transporter; Region: CDF; TIGR01297 413999005748 Pfam match to entry PF01545 Cation_efflux, Cation efflux family, score 306.5, E-value 3.3e-89 413999005749 2 probable transmembrane helices predicted for CBO1274 by TMHMM2.0 at aa 13-35 and 86-108 413999005750 Predicted membrane protein [Function unknown]; Region: COG2323 413999005751 3 probable transmembrane helices predicted for CBO1275 by TMHMM2.0 at aa 4-26, 33-55 and 59-81 413999005752 Pfam match to entry PF04239 DUF421, Protein of unknown function (DUF421), score 203.7, E-value 3e-58 413999005753 Domain of unknown function (DUF4363); Region: DUF4363; pfam14276 413999005754 1 probable transmembrane helix predicted for CBO1276 by TMHMM2.0 at aa 4-26 413999005755 Sporulation protein YtrH; Region: Spore_YtrH; pfam14034 413999005756 3 probable transmembrane helices predicted for CBO1277 by TMHMM2.0 at aa 13-35, 50-72 and 84-103 413999005757 Protein of unknown function (DUF3267); Region: DUF3267; pfam11667 413999005758 3 probable transmembrane helices predicted for CBO1279 by TMHMM2.0 at aa 2-24, 53-75 and 82-104 413999005759 A short protein domain of unknown function; Region: IDEAL; smart00914 413999005760 3 probable transmembrane helices predicted for CBO1283 by TMHMM2.0 at aa 7-29, 39-61 and 68-90 413999005761 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999005762 PQ loop repeat; Region: PQ-loop; cl17546 413999005763 3 probable transmembrane helices predicted for CBO1284 by TMHMM2.0 at aa 10-28, 41-63 and 67-89 413999005764 xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970 413999005765 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 413999005766 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 413999005767 Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain,score 150.8, E-value 2.5e-42 413999005768 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999005769 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain, score 582.2, E-value 3.3e-172 413999005770 xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971 413999005771 CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092 413999005772 Pfam match to entry PF00941 FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase, score 121.6, E-value 1.5e-33 413999005773 Pfam match to entry PF03450 CO_deh_flav_C, CO dehydrogenase flavoprotein C-terminal domain, score 15.8,E-value 7.1e-05 413999005774 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 413999005775 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 413999005776 catalytic loop [active] 413999005777 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 413999005778 iron binding site [ion binding]; other site 413999005779 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 413999005780 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain, score 25.8, E-value 0.0001 413999005781 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 413999005782 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005783 Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding domain, score 115.0, E-value 1.5e-31 413999005784 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 413999005785 nucleoside/Zn binding site; other site 413999005786 dimer interface [polypeptide binding]; other site 413999005787 catalytic motif [active] 413999005788 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region, score 115.6, E-value 1e-31 413999005789 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 413999005790 PS00127 Pancreatic ribonuclease signature. 413999005791 DNA topoisomerase III; Provisional; Region: PRK07726 413999005792 TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362 413999005793 active site 413999005794 putative interdomain interaction site [polypeptide binding]; other site 413999005795 putative metal-binding site [ion binding]; other site 413999005796 putative nucleotide binding site [chemical binding]; other site 413999005797 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 413999005798 domain I; other site 413999005799 DNA binding groove [nucleotide binding] 413999005800 phosphate binding site [ion binding]; other site 413999005801 domain II; other site 413999005802 domain III; other site 413999005803 nucleotide binding site [chemical binding]; other site 413999005804 catalytic site [active] 413999005805 domain IV; other site 413999005806 Pfam match to entry PF01751 Toprim, Toprim domain,score 75.8, E-value 9.2e-20 413999005807 Pfam match to entry PF01131 Topoisom_bac, DNA topoisomerase, score 468.9, E-value 4.3e-138 413999005808 PS00396 Prokaryotic DNA topoisomerase I active site. 413999005809 Predicted membrane protein [Function unknown]; Region: COG1971 413999005810 Domain of unknown function DUF; Region: DUF204; pfam02659 413999005811 6 probable transmembrane helices predicted for CBO1290 by TMHMM2.0 at aa 4-26, 39-59, 64-86, 115-137,141-163 and 176-198 413999005812 Pfam match to entry PF02659 DUF204, Domain of unknown function DUF, score 62.1, E-value 1.3e-15 413999005813 Pfam match to entry PF02659 DUF204, Domain of unknown function DUF, score 93.4, E-value 4.7e-25 413999005814 Uncharacterized conserved protein (DUF2164); Region: DUF2164; pfam09932 413999005815 Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956 413999005816 active site 413999005817 intersubunit interactions; other site 413999005818 catalytic residue [active] 413999005819 Pfam match to entry PF00923 Transaldolase,Transaldolase, score 274.7, E-value 1.2e-79 413999005820 PS01054 Transaldolase signature 1. 413999005821 mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595 413999005822 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999005823 RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521 413999005824 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 94.9, E-value 1.7e-25 413999005825 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999005826 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 413999005827 12 probable transmembrane helices predicted for CBO1294 by TMHMM2.0 at aa 2-19, 34-56, 89-111, 116-138,166-188, 203-225, 232-249, 259-281, 320-342, 370-392,405-424 and 434-453 413999005828 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 540.5, E-value 1.2e-159 413999005829 PS00873 Sodium:alanine symporter family signature. 413999005830 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999005831 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999005832 metal binding site [ion binding]; metal-binding site 413999005833 active site 413999005834 I-site; other site 413999005835 3 probable transmembrane helices predicted for CBO1295 by TMHMM2.0 at aa 10-29, 34-56 and 61-80 413999005836 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 0.3, E-value 4.1e-08 413999005837 Putative NodB-like catalytic domain of uncharacterized proteins found in bacteria; Region: CE4_COG5298; cd10923 413999005838 Uncharacterized protein conserved in bacteria (DUF2334); Region: DUF2334; pfam10096 413999005839 NodB motif; other site 413999005840 putative active site [active] 413999005841 putative catalytic site [active] 413999005842 putative Zn binding site [ion binding]; other site 413999005843 1 probable transmembrane helix predicted for CBO1296 by TMHMM2.0 at aa 518-540 413999005844 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 413999005845 CESA_like is the cellulose synthase superfamily; Region: CESA_like; cd06423 413999005846 DXD motif; other site 413999005847 4 probable transmembrane helices predicted for CBO1297 by TMHMM2.0 at aa 10-32, 309-331, 346-365 and 378-400 413999005848 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 117.7, E-value 2.3e-32 413999005849 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 413999005850 Bacterial cellulose synthase subunit; Region: BcsB; pfam03170 413999005851 2 probable transmembrane helices predicted for CBO1298 by TMHMM2.0 at aa 7-29 and 672-691 413999005852 1 probable transmembrane helix predicted for CBO1300 by TMHMM2.0 at aa 7-26 413999005853 Probable zinc-binding domain; Region: zf-trcl; pfam13451 413999005854 Protein of unknown function (DUF2837); Region: DUF2837; pfam10997 413999005855 6 probable transmembrane helices predicted for CBO1302 by TMHMM2.0 at aa 5-27, 39-61, 76-98, 159-181,196-218 and 231-253 413999005856 Uncharacterized family 2; belongs to a superfamily containing transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156; Region: CsoR-like_DUF156_2; cd10159 413999005857 putative homodimer interface [polypeptide binding]; other site 413999005858 putative homotetramer interface [polypeptide binding]; other site 413999005859 putative allosteric switch controlling residues; other site 413999005860 putative metal binding site [ion binding]; other site 413999005861 putative homodimer-homodimer interface [polypeptide binding]; other site 413999005862 Pfam match to entry PF02583 DUF156, Uncharacterised BCR, COG1937, score 62.8, E-value 7.6e-16 413999005863 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 413999005864 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 413999005865 metal-binding site [ion binding] 413999005866 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 413999005867 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 413999005868 metal-binding site [ion binding] 413999005869 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999005870 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999005871 motif II; other site 413999005872 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 79.3, E-value 8.1e-21 413999005873 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 70.7, E-value 3.2e-18 413999005874 8 probable transmembrane helices predicted for CBO1304 by TMHMM2.0 at aa 160-182, 197-219, 232-253,263-285, 415-437, 441-463, 756-778 and 782-804 413999005875 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 358.4, E-value 8.2e-105 413999005876 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005877 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 141.8, E-value 1.3e-39 413999005878 PS00154 E1-E2 ATPases phosphorylation site. 413999005879 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 413999005880 metal-binding site [ion binding] 413999005881 Pfam match to entry PF00403 HMA,Heavy-metal-associated domain, score 44.1, E-value 3.4e-10 413999005882 PS01047 Heavy-metal-associated domain. 413999005883 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474 413999005884 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999005885 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 413999005886 Soluble P-type ATPase [General function prediction only]; Region: COG4087 413999005887 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 413999005888 10 probable transmembrane helices predicted for CBO1306 by TMHMM2.0 at aa 45-64, 69-87, 216-238, 253-275,596-618, 623-645, 665-687, 692-709, 716-738 and 748-770 413999005889 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 140.9, E-value 2.5e-39 413999005890 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 80.1, E-value 4.9e-21 413999005891 PS00154 E1-E2 ATPases phosphorylation site. 413999005892 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999005893 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999005894 ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251 413999005895 Walker A/P-loop; other site 413999005896 ATP binding site [chemical binding]; other site 413999005897 Q-loop/lid; other site 413999005898 ABC transporter signature motif; other site 413999005899 Walker B; other site 413999005900 D-loop; other site 413999005901 H-loop/switch region; other site 413999005902 4 probable transmembrane helices predicted for CBO1308 by TMHMM2.0 at aa 15-32, 52-74, 136-170 and 241-263 413999005903 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 128.3, E-value 1.5e-35 413999005904 Pfam match to entry PF00005 ABC_tran, ABC transporter score 226.2, E-value 4.9e-65 413999005905 PS00017 ATP/GTP-binding site motif A (P-loop). 413999005906 PS00211 ABC transporters family signature. 413999005907 CAAX protease self-immunity; Region: Abi; pfam02517 413999005908 7 probable transmembrane helices predicted for CBO1309 by TMHMM2.0 at aa 25-47, 52-74, 87-106, 135-157,170-189, 193-215 and 236-255 413999005909 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 91.9, E-value 1.3e-24 413999005910 Uncharacterized conserved protein [Function unknown]; Region: COG1433 413999005911 Pfam match to entry PF02579 Nitro_FeMo-Co,Dinitrogenase iron-molybdenum cofactor, score 77.0,E-value 4.2e-20 413999005912 EDD domain protein, DegV family; Region: DegV; TIGR00762 413999005913 Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645 413999005914 Pfam match to entry PF02645 DUF194, Uncharacterized protein, DegV family COG1307, score 232.2, E-value 7.6e-67 413999005915 1 probable transmembrane helix predicted for CBO1311 by TMHMM2.0 at aa 262-284 413999005916 Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467 413999005917 2 probable transmembrane helices predicted for CBO1313 by TMHMM2.0 at aa 7-29 and 44-66 413999005918 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537 413999005919 nucleotide binding site/active site [active] 413999005920 HIT family signature motif; other site 413999005921 catalytic residue [active] 413999005922 Pfam match to entry PF01230 HIT, HIT domain, score 101.0, E-value 2.5e-27 413999005923 Membrane protein of unknown function; Region: DUF360; pfam04020 413999005924 4 probable transmembrane helices predicted for CBO1315 by TMHMM2.0 at aa 15-37, 44-63, 73-95 and 100-119 413999005925 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 413999005926 Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750 413999005927 Pfam match to entry PF01478 Peptidase_A24, Type IV leader peptidase, score 125.7, E-value 9.2e-35 413999005928 7 probable transmembrane helices predicted for CBO1316 by TMHMM2.0 at aa 4-21, 68-90, 95-112, 119-138,148-165, 177-210 and 225-247 413999005929 YibE/F-like protein; Region: YibE_F; pfam07907 413999005930 7 probable transmembrane helices predicted for CBO1317 by TMHMM2.0 at aa 21-39, 130-152, 172-194,209-231, 252-274, 307-329 and 350-372 413999005931 potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496 413999005932 TrkA-N domain; Region: TrkA_N; pfam02254 413999005933 TrkA-C domain; Region: TrkA_C; pfam02080 413999005934 TrkA-N domain; Region: TrkA_N; pfam02254 413999005935 TrkA-C domain; Region: TrkA_C; pfam02080 413999005936 Pfam match to entry PF02254 TrkA-N, TrkA-N domain,score 117.8, E-value 2.1e-32 413999005937 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 60.0, E-value 5.4e-15 413999005938 Pfam match to entry PF02254 TrkA-N, TrkA-N domain,score 54.0, E-value 3.3e-13 413999005939 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 49.1, E-value 1.1e-11 413999005940 Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168 413999005941 potassium uptake protein, TrkH family; Region: 2a38; TIGR00933 413999005942 10 probable transmembrane helices predicted for CBO1319 by TMHMM2.0 at aa 13-32, 37-56, 69-91, 131-153,183-202, 232-254, 274-296, 330-352, 392-414 and 453-475 413999005943 Pfam match to entry PF02386 TrkH, Cation transport protein, score 186.7, E-value 4e-53 413999005944 1 probable transmembrane helix predicted for CBO1320 by TMHMM2.0 at aa 15-37 413999005945 UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580 413999005946 Part of AAA domain; Region: AAA_19; pfam13245 413999005947 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 413999005948 active site 413999005949 catalytic site [active] 413999005950 substrate binding site [chemical binding]; other site 413999005951 Family description; Region: UvrD_C_2; pfam13538 413999005952 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 204.4, E-value 1.8e-58 413999005953 Pfam match to entry PF00929 Exonuclease,Exonuclease, score 114.7, E-value 1.8e-31 413999005954 Predicted membrane protein [General function prediction only]; Region: COG4194 413999005955 Protein of unknown function (DUF1648); Region: DUF1648; pfam07853 413999005956 7 probable transmembrane helices predicted for CBO1322 by TMHMM2.0 at aa 9-30, 35-54, 91-113, 144-166,190-209, 224-246 and 307-329 413999005957 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999005958 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999005959 DNA-binding site [nucleotide binding]; DNA binding site 413999005960 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 64.5, E-value 2.4e-16 413999005961 PS00043 Bacterial regulatory proteins, gntR family signature. 413999005962 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999005963 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999005964 Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486 413999005965 Pfam match to entry PF01476 LysM, LysM domain,score 57.8, E-value 2.5e-14 413999005966 Pfam match to entry PF01476 LysM, LysM domain,score 58.5, E-value 1.5e-14 413999005967 Rubrerythrin [Energy production and conversion]; Region: COG1592 413999005968 Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041 413999005969 binuclear metal center [ion binding]; other site 413999005970 Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729 413999005971 iron binding site [ion binding]; other site 413999005972 Pfam match to entry PF02915 Rubrerythrin,Rubrerythrin, score 224.7, E-value 1.4e-64 413999005973 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999005974 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999005975 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999005976 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 44.5, E-value 2.5e-10 413999005977 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 67.8, E-value 2.5e-17 413999005978 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 48.9, E-value 1.2e-11 413999005979 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999005980 PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002 413999005981 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999005982 active site turn [active] 413999005983 phosphorylation site [posttranslational modification] 413999005984 PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210 413999005985 HPr interaction site; other site 413999005986 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999005987 active site 413999005988 phosphorylation site [posttranslational modification] 413999005989 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 219.9, E-value 4e-63 413999005990 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999005991 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 56.2, E-value 7.4e-14 413999005992 11 probable transmembrane helices predicted for CBO1327 by TMHMM2.0 at aa 15-34, 63-85, 89-111, 123-145,169-191, 211-233, 268-290, 303-320, 324-346, 353-375 and 380-402 413999005993 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 380.9, E-value 1.4e-111 413999005994 Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020 413999005995 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230 413999005996 catalytic residue [active] 413999005997 putative FPP diphosphate binding site; other site 413999005998 putative FPP binding hydrophobic cleft; other site 413999005999 dimer interface [polypeptide binding]; other site 413999006000 putative IPP diphosphate binding site; other site 413999006001 Pfam match to entry PF01255 UPP_synthetase,UDP diphosphate synthase, score 22.1,E-value 2.5e-13 413999006002 Rrf2 family protein; Region: rrf2_super; TIGR00738 413999006003 Transcriptional regulator; Region: Rrf2; pfam02082 413999006004 Pfam match to entry PF02082 Rrf2, Transcriptional regulator, score 107.5, E-value 2.7e-29 413999006005 PS01332 Uncharacterized protein family UPF0074 signature. 413999006006 carbon-monoxide dehydrogenase, catalytic subunit; Region: CO_DH_cata; TIGR01702 413999006007 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999006008 ACS interaction site; other site 413999006009 CODH interaction site; other site 413999006010 metal cluster binding site [ion binding]; other site 413999006011 Pfam match to entry PF03063 Prismane, Prismane/CO dehydrogenase, score 659.6, E-value 1.7e-195 413999006012 4Fe-4S dicluster domain; Region: Fer4_11; pfam13247 413999006013 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999006014 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 23.2, E-value 5.7e-05 413999006015 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999006016 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 413999006017 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999006018 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 226.2, E-value 4.9e-65 413999006019 EamA-like transporter family; Region: EamA; pfam00892 413999006020 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 413999006021 EamA-like transporter family; Region: EamA; pfam00892 413999006022 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 76.5, E-value 5.8e-20 413999006023 12 probable transmembrane helices predicted for CBO1334 by TMHMM2.0 at aa 5-27, 32-51, 78-95, 110-127,140-162, 166-188, 201-220, 230-247, 260-277, 292-314,321-343 and 348-366 413999006024 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 32.9, E-value 8e-07 413999006025 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 413999006026 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 413999006027 ligand binding site [chemical binding]; other site 413999006028 flexible hinge region; other site 413999006029 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 413999006030 putative switch regulator; other site 413999006031 non-specific DNA interactions [nucleotide binding]; other site 413999006032 DNA binding site [nucleotide binding] 413999006033 sequence specific DNA binding site [nucleotide binding]; other site 413999006034 putative cAMP binding site [chemical binding]; other site 413999006035 Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family, score 34.3, E-value 3e-07 413999006036 Predicted helix-turn-helix motif with score 1352.000, SD 3.79 at aa 187-208, sequence YSHEEIAQLIGSCRVTVTKILN 413999006037 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain, score 78.3, E-value 1.6e-20 413999006038 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999006039 Major Facilitator Superfamily; Region: MFS_1; pfam07690 413999006040 putative substrate translocation pore; other site 413999006041 12 probable transmembrane helices predicted for CBO1336 by TMHMM2.0 at aa 13-35, 45-64, 77-99, 104-123,135-157, 167-189, 216-238, 248-266, 273-295, 300-322,334-356 and 366-388 413999006042 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -86.2, E-value 0.00041 413999006043 PS00216 Sugar transport proteins signature 1. 413999006044 PS00012 Phosphopantetheine attachment site. 413999006045 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999006046 Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143 413999006047 putative binding site residues; other site 413999006048 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006049 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 124.7, E-value 1.8e-34 413999006050 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 413999006051 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999006052 ABC-ATPase subunit interface; other site 413999006053 dimer interface [polypeptide binding]; other site 413999006054 putative PBP binding regions; other site 413999006055 9 probable transmembrane helices predicted for CBO1338 by TMHMM2.0 at aa 7-29, 62-84, 91-110, 116-138,150-172, 192-211, 243-265, 280-302 and 309-327 413999006056 Pfam match to entry PF01032 FecCD, FecCD transport family, score 347.4, E-value 1.6e-101 413999006057 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 413999006058 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999006059 Walker A/P-loop; other site 413999006060 ATP binding site [chemical binding]; other site 413999006061 Q-loop/lid; other site 413999006062 ABC transporter signature motif; other site 413999006063 Walker B; other site 413999006064 D-loop; other site 413999006065 H-loop/switch region; other site 413999006066 Pfam match to entry PF00005 ABC_tran, ABC transporter score 175.0, E-value 1.3e-49 413999006067 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006068 PS00211 ABC transporters family signature. 413999006069 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999006070 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 413999006071 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 32.2, E-value 1.2e-06 413999006072 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 39.2, E-value 1e-08 413999006073 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999006074 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999006075 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999006076 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999006077 putative active site [active] 413999006078 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family, score 78.9, E-value 1.1e-20 413999006079 Pfam match to entry PF01380 SIS, SIS domain, score 101.2, E-value 2.1e-27 413999006080 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006081 N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441 413999006082 N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007 413999006083 putative active site [active] 413999006084 Pfam match to entry PF01380 SIS, SIS domain, score 4.4, E-value 0.015 413999006085 PS01272 Glucokinase regulatory protein family signature. 413999006086 PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996 413999006087 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164 413999006088 active site turn [active] 413999006089 phosphorylation site [posttranslational modification] 413999006090 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999006091 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 44.4, E-value 2.7e-10 413999006092 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999006093 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 157.5, E-value 2.4e-44 413999006094 9 probable transmembrane helices predicted for CBO1344 by TMHMM2.0 at aa 123-145, 155-177, 213-232,247-269, 282-304, 324-346, 358-380, 395-417 and 424-446 413999006095 Uncharacterized conserved protein [Function unknown]; Region: COG3589 413999006096 Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913 413999006097 Pfam match to entry PF05913 DUF871, Bacterial protein of unknown function (DUF871), score 371.8, E-value 7.2e-109 413999006098 Putative glycolipid-binding; Region: Glycolipid_bind; pfam06475 413999006099 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 413999006100 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999006101 Domain of unknown function (DUF4396); Region: DUF4396; pfam14342 413999006102 8 probable transmembrane helices predicted for CBO1350 by TMHMM2.0 at aa 7-24, 393-415, 422-444, 459-481,486-508, 518-540, 553-575 and 590-612 413999006103 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999006104 1 probable transmembrane helix predicted for CBO1351 by TMHMM2.0 at aa 13-32 413999006105 2 probable transmembrane helices predicted for CBO1352 by TMHMM2.0 at aa 85-107 and 122-144 413999006106 Protein of unknown function (DUF1657); Region: DUF1657; pfam07870 413999006107 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 413999006108 HAMP domain; Region: HAMP; pfam00672 413999006109 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999006110 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999006111 dimer interface [polypeptide binding]; other site 413999006112 putative CheW interface [polypeptide binding]; other site 413999006113 2 probable transmembrane helices predicted for CBO1354 by TMHMM2.0 at aa 10-32 and 186-208 413999006114 Pfam match to entry PF00672 HAMP, HAMP domain,score 34.9, E-value 2e-07 413999006115 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 73.1, E-value 6.3e-19 413999006116 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 413999006117 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518 413999006118 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006119 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, score 355.2, E-value 7.1e-104 413999006120 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 413999006121 PS00092 N-6 Adenine-specific DNA methylases signature. 413999006122 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 413999006123 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006124 dimer interface [polypeptide binding]; other site 413999006125 conserved gate region; other site 413999006126 putative PBP binding loops; other site 413999006127 ABC-ATPase subunit interface; other site 413999006128 6 probable transmembrane helices predicted for CBO1356 by TMHMM2.0 at aa 20-42, 113-135, 148-170,196-215, 249-271 and 299-321 413999006129 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 128.5, E-value 1.3e-35 413999006130 nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790 413999006131 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006132 dimer interface [polypeptide binding]; other site 413999006133 conserved gate region; other site 413999006134 putative PBP binding loops; other site 413999006135 ABC-ATPase subunit interface; other site 413999006136 6 probable transmembrane helices predicted for CBO1357 by TMHMM2.0 at aa 5-27, 73-95, 108-125, 129-148,179-201 and 234-256 413999006137 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 126.0, E-value 7.1e-35 413999006138 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 413999006139 nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770 413999006140 Walker A/P-loop; other site 413999006141 ATP binding site [chemical binding]; other site 413999006142 Q-loop/lid; other site 413999006143 ABC transporter signature motif; other site 413999006144 Walker B; other site 413999006145 D-loop; other site 413999006146 H-loop/switch region; other site 413999006147 Pfam match to entry PF00005 ABC_tran, ABC transporter score 162.1, E-value 1e-45 413999006148 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006149 PS00211 ABC transporters family signature. 413999006150 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 413999006151 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 413999006152 Walker A/P-loop; other site 413999006153 ATP binding site [chemical binding]; other site 413999006154 Q-loop/lid; other site 413999006155 ABC transporter signature motif; other site 413999006156 Walker B; other site 413999006157 D-loop; other site 413999006158 H-loop/switch region; other site 413999006159 Pfam match to entry PF00005 ABC_tran, ABC transporter score 169.9, E-value 4.4e-48 413999006160 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006161 PS00211 ABC transporters family signature. 413999006162 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 413999006163 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999006164 ABC-ATPase subunit interface; other site 413999006165 dimer interface [polypeptide binding]; other site 413999006166 putative PBP binding regions; other site 413999006167 Pfam match to entry PF00950 ABC-3, ABC 3 transport family, score 215.8, E-value 6.6e-62 413999006168 8 probable transmembrane helices predicted for CBO1361 by TMHMM2.0 at aa 9-31, 51-73, 86-108, 128-150,162-181, 185-207, 214-236 and 241-258 413999006169 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 413999006170 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 413999006171 Pfam match to entry PF00005 ABC_tran, ABC transporter score 152.8, E-value 6.3e-43 413999006172 PS00211 ABC transporters family signature. 413999006173 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006174 Metal binding protein AcdA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017 413999006175 Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297 413999006176 metal binding site [ion binding]; metal-binding site 413999006177 Pfam match to entry PF01297 SBP_bac_9, Periplasmic solute binding protein family, score 350.6, E-value 1.7e-102 413999006178 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006179 3 probable transmembrane helices predicted for CBO1364 by TMHMM2.0 at aa 16-38, 64-82 and 102-124 413999006180 Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513 413999006181 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999006182 nucleotide binding region [chemical binding]; other site 413999006183 ATP-binding site [chemical binding]; other site 413999006184 Mitochondrial degradasome RNA helicase subunit C terminal; Region: SUV3_C; pfam12513 413999006185 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006186 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 65.7, E-value 1.1e-16 413999006187 PS00037 Myb DNA-binding domain repeat signature 1. 413999006188 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999006189 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999006190 metal binding site [ion binding]; metal-binding site 413999006191 active site 413999006192 I-site; other site 413999006193 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 85.3, E-value 1.3e-22 413999006194 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 413999006195 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 413999006196 1 probable transmembrane helix predicted for CBO1368 by TMHMM2.0 at aa 5-22 413999006197 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006198 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 413999006199 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427 413999006200 6 probable transmembrane helices predicted for CBO1369 by TMHMM2.0 at aa 31-53, 80-102, 115-134, 138-160,180-202 and 238-260 413999006201 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 50.9, E-value 3e-12 413999006202 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999006203 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999006204 Walker A/P-loop; other site 413999006205 ATP binding site [chemical binding]; other site 413999006206 Q-loop/lid; other site 413999006207 ABC transporter signature motif; other site 413999006208 Walker B; other site 413999006209 D-loop; other site 413999006210 H-loop/switch region; other site 413999006211 Pfam match to entry PF00005 ABC_tran, ABC transporter score 133.8, E-value 3.2e-37 413999006212 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006213 PS00211 ABC transporters family signature. 413999006214 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 413999006215 metal binding site 2 [ion binding]; metal-binding site 413999006216 putative DNA binding helix; other site 413999006217 metal binding site 1 [ion binding]; metal-binding site 413999006218 dimer interface [polypeptide binding]; other site 413999006219 structural Zn2+ binding site [ion binding]; other site 413999006220 Pfam match to entry PF01475 FUR, Ferric uptake regulator family, score 80.4, E-value 3.8e-21 413999006221 Predicted DNA-binding proteins [General function prediction only]; Region: COG1342 413999006222 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 413999006223 Pfam match to entry PF02001 DUF134, Protein of unknown function DUF134, score 90.6, E-value 3.3e-24 413999006224 Predicted helix-turn-helix motif with score 1595.000, SD 4.62 at aa 50-71, sequence LNQEQCAEKMEISRQTFQNIID 413999006225 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 413999006226 FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388 413999006227 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999006228 Peptidase M14 carboxypeptidase family-like domain of Endopeptidase I; Region: M14_Endopeptidase_I; cd06229 413999006229 putative active site [active] 413999006230 Zn binding site [ion binding]; other site 413999006231 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain, score 74.4, E-value 2.5e-19 413999006232 Pfam match to entry PF01476 LysM, LysM domain,score 60.6, E-value 3.5e-15 413999006233 Pfam match to entry PF00246 Zn_carbOpept, Zinc carboxypeptidase, score 53.5, E-value 4.9e-13 413999006234 ribonuclease Z; Region: RNase_Z; TIGR02651 413999006235 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 39.3, E-value 9.2e-09 413999006236 L-type amino acid transporter; Region: 2A0308; TIGR00911 413999006237 12 probable transmembrane helices predicted for CBO1377 by TMHMM2.0 at aa 13-33, 48-70, 91-113, 133-152,157-176, 196-218, 231-253, 268-290, 330-352, 357-374,387-406 and 411-433 413999006238 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score 160.6, E-value 2.7e-45 413999006239 Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225 413999006240 pentamer interface [polypeptide binding]; other site 413999006241 dodecaamer interface [polypeptide binding]; other site 413999006242 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 413999006243 Histidine kinase; Region: HisKA_3; pfam07730 413999006244 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999006245 ATP binding site [chemical binding]; other site 413999006246 Mg2+ binding site [ion binding]; other site 413999006247 G-X-G motif; other site 413999006248 5 probable transmembrane helices predicted for CBO1379 by TMHMM2.0 at aa 7-25, 29-51, 58-80, 100-117 and 124-141 413999006249 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 42.5,E-value 1e-09 413999006250 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 413999006251 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999006252 active site 413999006253 phosphorylation site [posttranslational modification] 413999006254 intermolecular recognition site; other site 413999006255 dimerization interface [polypeptide binding]; other site 413999006256 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 413999006257 DNA binding residues [nucleotide binding] 413999006258 dimerization interface [polypeptide binding]; other site 413999006259 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 130.2, E-value 3.8e-36 413999006260 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family, score 60.8, E-value 3e-15 413999006261 Predicted helix-turn-helix motif with score 1497.000, SD 4.29 at aa 171-192, sequence LSNKEIAEKIYLSEGTIKNNIS 413999006262 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999006263 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999006264 Walker A/P-loop; other site 413999006265 ATP binding site [chemical binding]; other site 413999006266 Q-loop/lid; other site 413999006267 ABC transporter signature motif; other site 413999006268 Walker B; other site 413999006269 D-loop; other site 413999006270 H-loop/switch region; other site 413999006271 Pfam match to entry PF00005 ABC_tran, ABC transporter score 200.0, E-value 3.8e-57 413999006272 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006273 PS00211 ABC transporters family signature. 413999006274 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 413999006275 6 probable transmembrane helices predicted for CBO1382 by TMHMM2.0 at aa 20-39, 196-218, 239-261,276-298, 305-324 and 362-384 413999006276 ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698 413999006277 6 probable transmembrane helices predicted for CBO1383 by TMHMM2.0 at aa 20-39, 175-197, 218-240,255-277, 284-306 and 338-360 413999006278 2 probable transmembrane helices predicted for CBO1384 by TMHMM2.0 at aa 12-31 and 36-58 413999006279 Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062 413999006280 FMN binding site [chemical binding]; other site 413999006281 dimer interface [polypeptide binding]; other site 413999006282 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 93.9, E-value 3.4e-25 413999006283 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 413999006284 DNA-binding site [nucleotide binding]; DNA binding site 413999006285 RNA-binding motif; other site 413999006286 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain, score 131.9, E-value 1.2e-36 413999006287 PS00352 'Cold-shock' DNA-binding domain signature. 413999006288 M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890 413999006289 Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893 413999006290 metal binding site [ion binding]; metal-binding site 413999006291 dimer interface [polypeptide binding]; other site 413999006292 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 80.5, E-value 3.6e-21 413999006293 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999006294 1 probable transmembrane helix predicted for CBO1389 by TMHMM2.0 at aa 7-29 413999006295 Pfam match to entry PF00515 TPR, TPR Domain, score 25.3, E-value 0.00015 413999006296 Pfam match to entry PF00515 TPR, TPR Domain, score 7.0, E-value 0.56 413999006297 Pfam match to entry PF00515 TPR, TPR Domain, score 15.0, E-value 0.062 413999006298 Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173 413999006299 dimer interface [polypeptide binding]; other site 413999006300 pyridoxal binding site [chemical binding]; other site 413999006301 ATP binding site [chemical binding]; other site 413999006302 Peptide methionine sulfoxide reductase; Region: PMSR; cl00366 413999006303 Pfam match to entry PF01625 PMSR, Peptide methionine sulfoxide reductase, score 133.9, E-value 3.1e-37 413999006304 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999006305 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999006306 Walker A/P-loop; other site 413999006307 ATP binding site [chemical binding]; other site 413999006308 Q-loop/lid; other site 413999006309 ABC transporter signature motif; other site 413999006310 Walker B; other site 413999006311 D-loop; other site 413999006312 H-loop/switch region; other site 413999006313 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999006314 FtsX-like permease family; Region: FtsX; pfam02687 413999006315 10 probable transmembrane helices predicted for CBO1392 by TMHMM2.0 at aa 21-38, 58-80, 101-123, 160-182,202-219, 229-251, 283-305, 512-534, 569-591 and 596-618 413999006316 Pfam match to entry PF02687 FtsX, Predicted permease, score 36.2, E-value 8e-08 413999006317 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 413999006318 1 probable transmembrane helix predicted for CBO1393 by TMHMM2.0 at aa 7-28 413999006319 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999006320 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999006321 active site 413999006322 phosphorylation site [posttranslational modification] 413999006323 intermolecular recognition site; other site 413999006324 dimerization interface [polypeptide binding]; other site 413999006325 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999006326 DNA binding site [nucleotide binding] 413999006327 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 93.1, E-value 5.8e-25 413999006328 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 58.8, E-value 1.2e-14 413999006329 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999006330 His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388 413999006331 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999006332 ATP binding site [chemical binding]; other site 413999006333 Mg2+ binding site [ion binding]; other site 413999006334 G-X-G motif; other site 413999006335 2 probable transmembrane helices predicted for CBO1395 by TMHMM2.0 at aa 11-33 and 38-55 413999006336 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 19.9, E-value 0.00087 413999006337 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 77.4,E-value 3.1e-20 413999006338 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999006339 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999006340 Walker A/P-loop; other site 413999006341 ATP binding site [chemical binding]; other site 413999006342 Q-loop/lid; other site 413999006343 ABC transporter signature motif; other site 413999006344 Walker B; other site 413999006345 D-loop; other site 413999006346 H-loop/switch region; other site 413999006347 Pfam match to entry PF00005 ABC_tran, ABC transporter score 197.0, E-value 3e-56 413999006348 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006349 10 probable transmembrane helices predicted for CBO1397 by TMHMM2.0 at aa 20-42, 62-84, 104-126, 154-173,185-207, 217-239, 270-292, 484-506, 540-559 and 574-592 413999006350 Predicted helix-turn-helix motif with score 1055.000, SD 2.78 at aa 516-537, sequence KGKYDILINLGISKKTVNSIIN 413999006351 Domain of unknown function (DUF4163); Region: DUF4163; pfam13739 413999006352 Protein of unknown function (DUF3298); Region: DUF3298; pfam11738 413999006353 Protein of unknown function (DUF2804); Region: DUF2804; pfam10974 413999006354 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168 413999006355 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999006356 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999006357 homodimer interface [polypeptide binding]; other site 413999006358 catalytic residue [active] 413999006359 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 38.3, E-value 1.8e-08 413999006360 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006361 dimer interface [polypeptide binding]; other site 413999006362 conserved gate region; other site 413999006363 putative PBP binding loops; other site 413999006364 ABC-ATPase subunit interface; other site 413999006365 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 92.8, E-value 7.3e-25 413999006366 4 probable transmembrane helices predicted for CBO1401 by TMHMM2.0 at aa 21-43, 63-85, 155-177 and 192-209 413999006367 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999006368 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 413999006369 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 413999006370 Walker A/P-loop; other site 413999006371 ATP binding site [chemical binding]; other site 413999006372 Q-loop/lid; other site 413999006373 ABC transporter signature motif; other site 413999006374 Walker B; other site 413999006375 D-loop; other site 413999006376 H-loop/switch region; other site 413999006377 Pfam match to entry PF00005 ABC_tran, ABC transporter score 228.0, E-value 1.4e-65 413999006378 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006379 PS00211 ABC transporters family signature. 413999006380 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999006381 non-specific DNA binding site [nucleotide binding]; other site 413999006382 salt bridge; other site 413999006383 sequence-specific DNA binding site [nucleotide binding]; other site 413999006384 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 28.9, E-value 1.3e-05 413999006385 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768 413999006386 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 413999006387 2 probable transmembrane helices predicted for CBO1404 by TMHMM2.0 at aa 7-26 and 386-408 413999006388 Pfam match to entry PF00768 Peptidase_S11,D-alanyl-D-alanine carboxypeptidase, score 148.0, E-value 1.7e-41 413999006389 Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426 413999006390 putative active site [active] 413999006391 putative CoA binding site [chemical binding]; other site 413999006392 nudix motif; other site 413999006393 metal binding site [ion binding]; metal-binding site 413999006394 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 37.6, E-value 3.1e-08 413999006395 PS00893 mutT domain signature. 413999006396 3 probable transmembrane helices predicted for CBO1406 by TMHMM2.0 at aa 4-26, 60-82 and 86-108 413999006397 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979 413999006398 Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187 413999006399 dimer interface [polypeptide binding]; other site 413999006400 active site 413999006401 metal binding site [ion binding]; metal-binding site 413999006402 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 457.4, E-value 1.2e-134 413999006403 PS00913 Iron-containing alcohol dehydrogenases signature 1. 413999006404 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006405 PS00060 Iron-containing alcohol dehydrogenases signature 2. 413999006406 Predicted membrane protein [Function unknown]; Region: COG1288 413999006407 C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606 413999006408 12 probable transmembrane helices predicted for CBO1409 by TMHMM2.0 at aa 13-35, 119-141, 162-181,186-208, 210-232, 242-264, 301-323, 328-347, 359-381,408-430, 451-473 and 488-510 413999006409 Pfam match to entry PF03606 DcuC, C4-dicarboxylate anaerobic carrier, score 552.1, E-value 4e-163 413999006410 nicotinate phosphoribosyltransferase; Validated; Region: PRK09243 413999006411 Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570 413999006412 active site 413999006413 Pfam match to entry PF04095 NAPRTase, Nicotinate phosphoribosyltransferase (NAPRTase) family, score 47.5,E-value 1.5e-13 413999006414 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 413999006415 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 413999006416 substrate binding pocket [chemical binding]; other site 413999006417 membrane-bound complex binding site; other site 413999006418 hinge residues; other site 413999006419 1 probable transmembrane helix predicted for CBO1411 by TMHMM2.0 at aa 7-24 413999006420 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006421 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, score 203.8, E-value 2.8e-58 413999006422 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 413999006423 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 413999006424 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006425 dimer interface [polypeptide binding]; other site 413999006426 conserved gate region; other site 413999006427 putative PBP binding loops; other site 413999006428 ABC-ATPase subunit interface; other site 413999006429 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 85.3, E-value 1.3e-22 413999006430 5 probable transmembrane helices predicted for CBO1412 by TMHMM2.0 at aa 20-42, 54-76, 91-113, 134-156 and 189-211 413999006431 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999006432 Protein of unknown function (DUF523); Region: DUF523; cl00733 413999006433 Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210 413999006434 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999006435 ATP binding site [chemical binding]; other site 413999006436 Family description; Region: UvrD_C_2; pfam13538 413999006437 PS00430 TonB-dependent receptor proteins signature 1. 413999006438 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 375.3, E-value 6.4e-110 413999006439 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006440 possible prophage 413999006441 2 probable transmembrane helices predicted for CBO1417 by TMHMM2.0 at aa 7-26 and 31-48 413999006442 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 413999006443 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999006444 Coenzyme A binding pocket [chemical binding]; other site 413999006445 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 60.6, E-value 3.6e-15 413999006446 1 probable transmembrane helix predicted for CBO1419 by TMHMM2.0 at aa 5-27 413999006447 Protein of unknown function (DUF2762); Region: DUF2762; pfam10960 413999006448 1 probable transmembrane helix predicted for CBO1422 by TMHMM2.0 at aa 5-27 413999006449 2 probable transmembrane helices predicted for CBO1423 by TMHMM2.0 at aa 13-31 and 35-52 413999006450 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999006451 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999006452 active site 413999006453 metal binding site [ion binding]; metal-binding site 413999006454 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 413999006455 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 63.2, E-value 5.8e-16 413999006456 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain, score 42.2, E-value 1.2e-09 413999006457 Coat F domain; Region: Coat_F; pfam07875 413999006458 2 probable transmembrane helices predicted for CBO1427 by TMHMM2.0 at aa 4-26 and 39-56 413999006459 cell division protein FtsA; Region: ftsA; TIGR01174 413999006460 Cell division protein FtsA; Region: FtsA; smart00842 413999006461 Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443 413999006462 Cell division protein FtsA; Region: FtsA; pfam14450 413999006463 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 413999006464 M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886 413999006465 metal binding site [ion binding]; metal-binding site 413999006466 dimer interface [polypeptide binding]; other site 413999006467 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 370.3, E-value 2.1e-108 413999006468 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999006469 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999006470 active site 413999006471 metal binding site [ion binding]; metal-binding site 413999006472 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006473 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 85.6, E-value 1e-22 413999006474 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 413999006475 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999006476 RNA binding surface [nucleotide binding]; other site 413999006477 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 413999006478 active site 413999006479 Pfam match to entry PF01479 S4, S4 domain, score 35.5, E-value 1.3e-07 413999006480 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase, score 112.3, E-value 9.8e-31 413999006481 PS01129 Rlu family of pseudouridine synthase signature. 413999006482 stage V sporulation protein B; Region: spore_V_B; TIGR02900 413999006483 Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124 413999006484 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 58.4, E-value 1.6e-14 413999006485 14 probable transmembrane helices predicted for CBO1434 by TMHMM2.0 at aa 12-34, 44-66, 87-109, 119-141,153-175, 185-204, 233-255, 285-307, 320-342, 357-379,384-406, 410-432, 453-475 and 488-510 413999006486 stage V sporulation protein B; Region: spore_V_B; TIGR02900 413999006487 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 413999006488 11 probable transmembrane helices predicted for CBO1435 by TMHMM2.0 at aa 12-34, 90-112, 125-147, 186-208,228-250, 283-305, 326-348, 358-380, 401-423, 450-472 and 479-496 413999006489 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 20.5, E-value 1.4e-05 413999006490 Uncharacterized family of ferritin-like proteins found in archaea and bacteria; Region: Ferritin_like_AB; cd01045 413999006491 diiron binding motif [ion binding]; other site 413999006492 Iron-containing alcohol dehydrogenase; Region: Fe-ADH8; cd08186 413999006493 Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465 413999006494 putative active site [active] 413999006495 metal binding site [ion binding]; metal-binding site 413999006496 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 167.6, E-value 2.2e-47 413999006497 AAA domain; Region: AAA_32; pfam13654 413999006498 Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067 413999006499 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 413999006500 Pfam match to entry PF05362 Lon_C, Lon protease (S16) C-terminal proteolytic domain, score -79.0, E-value 1.9e-08 413999006501 Pfam match to entry PF02868 Peptidase_M4_C,Thermolysin metallopeptidase, alpha-helical domain, score -19.5, E-value 4.2e-06 413999006502 1 probable transmembrane helix predicted for CBO1441 by TMHMM2.0 at aa 7-29 413999006503 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 413999006504 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 413999006505 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 413999006506 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 413999006507 active site 413999006508 Zn binding site [ion binding]; other site 413999006509 Pfam match to entry PF02868 Peptidase_M4_C,Thermolysin metallopeptidase, alpha-helical domain, score 210.0, E-value 3.7e-60 413999006510 Pfam match to entry PF01447 Peptidase_M4,Thermolysin metallopeptidase, catalytic domain, score 77.9, E-value 2.2e-20 413999006511 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999006512 Pfam match to entry PF03413 Pep_M4_propep,Thermolysin metallopeptidase, propeptide, score 32.5,E-value 1.7e-07 413999006513 1 probable transmembrane helix predicted for CBO1442 by TMHMM2.0 at aa 7-26 413999006514 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 413999006515 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 413999006516 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 413999006517 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 413999006518 active site 413999006519 Zn binding site [ion binding]; other site 413999006520 Pfam match to entry PF02868 Peptidase_M4_C,Thermolysin metallopeptidase, alpha-helical domain, score 213.6, E-value 3.1e-61 413999006521 Pfam match to entry PF01447 Peptidase_M4,Thermolysin metallopeptidase, catalytic domain, score 119.2, E-value 7.9e-33 413999006522 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999006523 Pfam match to entry PF03413 Pep_M4_propep,Thermolysin metallopeptidase, propeptide, score 49.3,E-value 9.1e-12 413999006524 1 probable transmembrane helix predicted for CBO1443 by TMHMM2.0 at aa 7-29 413999006525 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 413999006526 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 413999006527 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 413999006528 active site 413999006529 Zn binding site [ion binding]; other site 413999006530 Pfam match to entry PF02868 Peptidase_M4_C,Thermolysin metallopeptidase, alpha-helical domain, score 218.4, E-value 1.1e-62 413999006531 Pfam match to entry PF01447 Peptidase_M4,Thermolysin metallopeptidase, catalytic domain, score 121.3, E-value 1.8e-33 413999006532 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999006533 Pfam match to entry PF03413 Pep_M4_propep,Thermolysin metallopeptidase, propeptide, score 40.8,E-value 3.3e-09 413999006534 1 probable transmembrane helix predicted for CBO1444 by TMHMM2.0 at aa 7-29 413999006535 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 413999006536 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 413999006537 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 413999006538 active site 413999006539 Zn binding site [ion binding]; other site 413999006540 Pfam match to entry PF02868 Peptidase_M4_C,Thermolysin metallopeptidase, alpha-helical domain, score 195.2, E-value 1.1e-55 413999006541 Pfam match to entry PF01447 Peptidase_M4,Thermolysin metallopeptidase, catalytic domain, score 122.6, E-value 7.5e-34 413999006542 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999006543 Pfam match to entry PF03413 Pep_M4_propep,Thermolysin metallopeptidase, propeptide, score 45.2,E-value 1.6e-10 413999006544 1 probable transmembrane helix predicted for CBO1445 by TMHMM2.0 at aa 7-29 413999006545 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 413999006546 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 413999006547 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 413999006548 active site 413999006549 Zn binding site [ion binding]; other site 413999006550 Pfam match to entry PF02868 Peptidase_M4_C,Thermolysin metallopeptidase, alpha-helical domain, score 226.2, E-value 4.9e-65 413999006551 Pfam match to entry PF01447 Peptidase_M4,Thermolysin metallopeptidase, catalytic domain, score 106.9, E-value 4e-29 413999006552 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999006553 Pfam match to entry PF03413 Pep_M4_propep,Thermolysin metallopeptidase, propeptide, score 49.7,E-value 6.6e-12 413999006554 1 probable transmembrane helix predicted for CBO1446 by TMHMM2.0 at aa 7-29 413999006555 Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157 413999006556 Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572 413999006557 dimerization interface [polypeptide binding]; other site 413999006558 active site 413999006559 Pfam match to entry PF01729 QRPTase, Quinolinate phosphoribosyl transferase, C-terminal domain, score 308.6, E-value 7.8e-90 413999006560 Pfam match to entry PF02749 QRPTase_N, Quinolinate phosphoribosyl transferase, N-terminal domain, score 114.1, E-value 2.7e-31 413999006561 L-aspartate oxidase; Provisional; Region: PRK06175 413999006562 FAD binding domain; Region: FAD_binding_2; pfam00890 413999006563 Quinolinate synthetase A protein; Region: NadA; pfam02445 413999006564 Pfam match to entry PF02445 NadA, Quinolinate synthetase A protein, score 443.2, E-value 2.3e-130 413999006565 Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876 413999006566 metal binding site [ion binding]; metal-binding site 413999006567 2 probable transmembrane helices predicted for CBO1449 by TMHMM2.0 at aa 94-111 and 115-134 413999006568 Haemolysin-III related; Region: HlyIII; cl03831 413999006569 channel protein, hemolysin III family; Region: hlyIII; TIGR01065 413999006570 7 probable transmembrane helices predicted for CBO1450 by TMHMM2.0 at aa 15-37, 44-66, 76-98, 105-127,137-156, 161-180 and 190-209 413999006571 Pfam match to entry PF03006 UPF0073,Uncharacterised protein family (Hly-III / UPF0073), score 256.9, E-value 2.8e-74 413999006572 GTP-binding protein YchF; Reviewed; Region: PRK09601 413999006573 YchF GTPase; Region: YchF; cd01900 413999006574 G1 box; other site 413999006575 GTP/Mg2+ binding site [chemical binding]; other site 413999006576 Switch I region; other site 413999006577 G2 box; other site 413999006578 Switch II region; other site 413999006579 G3 box; other site 413999006580 G4 box; other site 413999006581 G5 box; other site 413999006582 TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867 413999006583 Pfam match to entry PF06071 DUF933, Protein of unknown function (DUF933), score 516.6, E-value 1.9e-152 413999006584 Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG family, score 35.5, E-value 2.4e-09 413999006585 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006586 cell division protein MraZ; Reviewed; Region: PRK00326 413999006587 MraZ protein; Region: MraZ; pfam02381 413999006588 MraZ protein; Region: MraZ; pfam02381 413999006589 Pfam match to entry PF02381 UPF0040, Domain of unknown function UPF0040 family, score 66.8, E-value 4.8e-17 413999006590 Pfam match to entry PF02381 UPF0040, Domain of unknown function UPF0040 family, score 69.9, E-value 5.7e-18 413999006591 MraW methylase family; Region: Methyltransf_5; pfam01795 413999006592 16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050 413999006593 Pfam match to entry PF01795 Methyltransf_5, MraW methylase, score 595.5, E-value 3.5e-176 413999006594 1 probable transmembrane helix predicted for CBO1455 by TMHMM2.0 at aa 57-74 413999006595 stage V sporulation protein D; Region: spoVD_pbp; TIGR02214 413999006596 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 413999006597 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 413999006598 PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576 413999006599 PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575 413999006600 1 probable transmembrane helix predicted for CBO1456 by TMHMM2.0 at aa 17-39 413999006601 Pfam match to entry PF03717 PBP_dimer,Penicillin-binding Protein dimerisation domain, score 129.9, E-value 4.8e-36 413999006602 Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain, score 363.0, E-value 3.4e-106 413999006603 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006604 Pfam match to entry PF03793 PASTA, PASTA domain,score 63.8, E-value 3.8e-16 413999006605 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999006606 Pfam match to entry PF03793 PASTA, PASTA domain,score 47.8, E-value 2.5e-11 413999006607 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139 413999006608 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 413999006609 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999006610 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 413999006611 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 249.4, E-value 5.1e-72 413999006612 PS01011 Folylpolyglutamate synthase signature 1. 413999006613 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006614 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain, score 111.4,E-value 1.8e-30 413999006615 UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770 413999006616 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 413999006617 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999006618 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 413999006619 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 142.6, E-value 7.4e-40 413999006620 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006621 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain, score 66.2,E-value 7.1e-17 413999006622 phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108 413999006623 Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852 413999006624 Mg++ binding site [ion binding]; other site 413999006625 putative catalytic motif [active] 413999006626 putative substrate binding site [chemical binding]; other site 413999006627 9 probable transmembrane helices predicted for CBO1459 by TMHMM2.0 at aa 5-27, 47-69, 76-93, 108-127,147-169, 192-214, 221-243, 248-270 and 298-316 413999006628 Pfam match to entry PF00953 Glycos_transf_4,Glycosyl transferase, score 151.6, E-value 1.4e-42 413999006629 Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511 413999006630 Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein, score 447.7, E-value 1e-131 413999006631 10 probable transmembrane helices predicted for CBO1460 by TMHMM2.0 at aa 13-34, 54-71, 83-100, 142-161,166-185, 190-212, 232-249, 275-297, 304-326 and 341-363 413999006632 PS00012 Phosphopantetheine attachment site. 413999006633 Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589 413999006634 POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478 413999006635 Pfam match to entry PF03799 FtsQ, Cell division protein FtsQ, score 73.7, E-value 3.9e-19 413999006636 1 probable transmembrane helix predicted for CBO1461 by TMHMM2.0 at aa 24-46 413999006637 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3879 413999006638 Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949 413999006639 1 probable transmembrane helix predicted for CBO1462 by TMHMM2.0 at aa 7-24 413999006640 Pfam match to entry PF05949 DUF881, Bacterial protein of unknown function (DUF881), score 212.8, E-value 5.5e-61 413999006641 Protein of unknown function (DUF1290); Region: DUF1290; pfam06947 413999006642 4 probable transmembrane helices predicted for CBO1463 by TMHMM2.0 at aa 2-21, 25-44, 56-75 and 79-101 413999006643 Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949 413999006644 1 probable transmembrane helix predicted for CBO1464 by TMHMM2.0 at aa 7-26 413999006645 Pfam match to entry PF05949 DUF881, Bacterial protein of unknown function (DUF881), score 148.4, E-value 1.3e-41 413999006646 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635 413999006647 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999006648 catalytic residue [active] 413999006649 Pfam match to entry PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain, score 107.9, E-value 2e-29 413999006650 Protein of unknown function (DUF552); Region: DUF552; cl00775 413999006651 Pfam match to entry PF04472 DUF552, Protein of unknown function (DUF552), score 108.7, E-value 1.1e-29 413999006652 YGGT family; Region: YGGT; pfam02325 413999006653 Pfam match to entry PF02325 YGGT, YGGT family,score 31.9, E-value 1.5e-06 413999006654 2 probable transmembrane helices predicted for CBO1467 by TMHMM2.0 at aa 12-31 and 68-90 413999006655 photosystem II S4 domain protein; Region: PS_II_S4; TIGR03069 413999006656 DivIVA protein; Region: DivIVA; pfam05103 413999006657 DivIVA domain; Region: DivI1A_domain; TIGR03544 413999006658 Pfam match to entry PF05103 DivIVA, DivIVA protein,score 82.0, E-value 1.3e-21 413999006659 Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195 413999006660 active site 413999006661 dimer interface [polypeptide binding]; other site 413999006662 metal binding site [ion binding]; metal-binding site 413999006663 Pfam match to entry PF01761 DHQ_synthase,3-dehydroquinate synthase, score 359.6, E-value 3.4e-105 413999006664 1 probable transmembrane helix predicted for CBO1470 by TMHMM2.0 at aa 97-119 413999006665 PS00211 ABC transporters family signature. 413999006666 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584 413999006667 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704 413999006668 Pfam match to entry PF01048 PNP_UDP_1,Phosphorylase, score 195.7, E-value 7.8e-56 413999006669 3-deoxy-7-phosphoheptulonate synthase; Provisional; Region: PRK13398 413999006670 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroA; COG2876 413999006671 Pfam match to entry PF00793 DAHP_synth_1, DAHP synthetase I family, score 330.1, E-value 2.7e-96 413999006672 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427 413999006673 EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556 413999006674 hinge; other site 413999006675 active site 413999006676 Pfam match to entry PF00275 EPSP_synthase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase),score 266.9, E-value 2.8e-77 413999006677 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006678 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006679 regulatory protein, yteA family; Region: bacill_yteA; TIGR02890 413999006680 Pfam match to entry PF01258 zf_dskA_traR,Prokaryotic dksA/traR C4-type zinc finger, score 32.1,E-value 1.4e-06 413999006681 lipoprotein signal peptidase; Provisional; Region: PRK14791 413999006682 lipoprotein signal peptidase; Provisional; Region: PRK14787 413999006683 Pfam match to entry PF01252 Peptidase_A8, Signal peptidase (SPase) II, score 113.1, E-value 5.5e-31 413999006684 3 probable transmembrane helices predicted for CBO1475 by TMHMM2.0 at aa 56-75, 88-105 and 120-142 413999006685 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 413999006686 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999006687 RNA binding surface [nucleotide binding]; other site 413999006688 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 413999006689 active site 413999006690 Pfam match to entry PF01479 S4, S4 domain, score 39.3, E-value 8.9e-09 413999006691 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase, score 263.8, E-value 2.4e-76 413999006692 PS01129 Rlu family of pseudouridine synthase signature. 413999006693 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065 413999006694 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999006695 active site 413999006696 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 70.7, E-value 3.2e-18 413999006697 uracil transporter; Provisional; Region: PRK10720 413999006698 12 probable transmembrane helices predicted for CBO1479 by TMHMM2.0 at aa 13-35, 40-59, 64-86, 90-112,119-141, 161-178, 185-207, 235-257, 308-330, 340-362,374-396 and 401-418 413999006699 Pfam match to entry PF00860 xan_ur_permease,Permease, score 406.1, E-value 3.5e-119 413999006700 PS01116 Xanthine/uracil permeases family signature. 413999006701 Methanothermobacter thermautotrophicus Mth212-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Mth212-like_AP-endo; cd09085 413999006702 active site 413999006703 putative catalytic site [active] 413999006704 phosphate binding site A [ion binding]; other site 413999006705 DNA binding site [nucleotide binding] 413999006706 metal binding site A [ion binding]; metal-binding site 413999006707 putative AP binding site [nucleotide binding]; other site 413999006708 putative metal binding site B [ion binding]; other site 413999006709 phosphate binding site B [ion binding]; other site 413999006710 Pfam match to entry PF03372 Exo_endo_phos,Endonuclease/Exonuclease/phosphatase, score 215.6,E-value 7.6e-62 413999006711 PS00726 AP endonucleases family 1 signature 1. 413999006712 Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116 413999006713 THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715 413999006714 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 413999006715 Pfam match to entry PF01170 UPF0020, RNA methylase UPF0020, score 240.4, E-value 2.7e-69 413999006716 PS01261 Uncharacterized protein family UPF0020 signature. 413999006717 PS00092 N-6 Adenine-specific DNA methylases signature. 413999006718 Carbonic anhydrase; Region: Pro_CA; smart00947 413999006719 active site clefts [active] 413999006720 zinc binding site [ion binding]; other site 413999006721 dimer interface [polypeptide binding]; other site 413999006722 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 413999006723 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 413999006724 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 56.5, E-value 6e-14 413999006725 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006726 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006727 dimer interface [polypeptide binding]; other site 413999006728 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 413999006729 conserved gate region; other site 413999006730 putative PBP binding loops; other site 413999006731 ABC-ATPase subunit interface; other site 413999006732 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 84.1, E-value 3e-22 413999006733 4 probable transmembrane helices predicted for CBO1484 by TMHMM2.0 at aa 7-29, 44-66, 79-101 and 191-213 413999006734 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006735 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999006736 putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608 413999006737 Walker A/P-loop; other site 413999006738 ATP binding site [chemical binding]; other site 413999006739 Q-loop/lid; other site 413999006740 ABC transporter signature motif; other site 413999006741 Walker B; other site 413999006742 D-loop; other site 413999006743 H-loop/switch region; other site 413999006744 Pfam match to entry PF00005 ABC_tran, ABC transporter score 180.1, E-value 3.9e-51 413999006745 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006746 PS00211 ABC transporters family signature. 413999006747 1 probable transmembrane helix predicted for CBO1486 by TMHMM2.0 at aa 7-29 413999006748 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 413999006749 ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207 413999006750 active site 413999006751 nucleophile elbow; other site 413999006752 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase, score 97.6, E-value 2.5e-26 413999006753 1 probable transmembrane helix predicted for CBO1487 by TMHMM2.0 at aa 30-52 413999006754 methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252 413999006755 The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465 413999006756 Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D), score 35.8, E-value 1.9e-12 413999006757 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006758 Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553 413999006759 11 probable transmembrane helices predicted for CBO1490 by TMHMM2.0 at aa 13-35, 42-64, 79-97, 118-140,160-179, 200-218, 228-250, 255-277, 297-319, 375-397 and 412-434 413999006760 Pfam match to entry PF03553 Na_H_antiporter, Na+/H+ antiporter family, score 130.6, E-value 2.9e-36 413999006761 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 413999006762 Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633 413999006763 Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894 413999006764 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain, score 22.7, E-value 0.00091 413999006765 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 413999006766 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999006767 Pfam match to entry PF02492 cobW, Cobalamin synthesis protein/P47K, score 154.0, E-value 2.7e-43 413999006768 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006769 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999006770 Uroporphyrinogen decarboxylase (URO-D); Region: URO-D; pfam01208 413999006771 Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D), score -134.9, E-value 0.00013 413999006772 Predicted cobalamin binding protein [General function prediction only]; Region: COG5012 413999006773 B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070 413999006774 B12 binding site [chemical binding]; other site 413999006775 cobalt ligand [ion binding]; other site 413999006776 Pfam match to entry PF02607 B12-binding_2, B12 binding domain, score 82.3, E-value 1.1e-21 413999006777 Pfam match to entry PF02310 B12-binding, B12 binding domain, score 125.5, E-value 1e-34 413999006778 methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252 413999006779 MtaA_CmuA_like family. MtaA/CmuA, also MtsA, or methyltransferase 2 (MT2) MT2-A and MT2-M isozymes, are methylcobamide:Coenzyme M methyltransferases, which play a role in metabolic pathways of methane formation from various substrates, such as methylated...; Region: Mta_CmuA_like; cd03307 413999006780 Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D), score 104.4, E-value 2.3e-28 413999006781 methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252 413999006782 The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465 413999006783 Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D), score 2.1, E-value 6.7e-11 413999006784 ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135 413999006785 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 413999006786 Walker A/P-loop; other site 413999006787 ATP binding site [chemical binding]; other site 413999006788 Q-loop/lid; other site 413999006789 ABC transporter signature motif; other site 413999006790 Walker B; other site 413999006791 D-loop; other site 413999006792 H-loop/switch region; other site 413999006793 This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930 413999006794 Pfam match to entry PF00005 ABC_tran, ABC transporter score 237.9, E-value 1.5e-68 413999006795 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006796 PS00211 ABC transporters family signature. 413999006797 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006798 dimer interface [polypeptide binding]; other site 413999006799 conserved gate region; other site 413999006800 ABC-ATPase subunit interface; other site 413999006801 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 63.9, E-value 3.6e-16 413999006802 4 probable transmembrane helices predicted for CBO1500 by TMHMM2.0 at aa 20-42, 57-79, 159-181 and 191-213 413999006803 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999006804 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 413999006805 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 413999006806 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006807 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein, score 183.0, E-value 5.2e-52 413999006808 MORN repeat; Region: MORN; cl14787 413999006809 MORN repeat; Region: MORN; cl14787 413999006810 MORN repeat; Region: MORN; cl14787 413999006811 Pfam match to entry PF02493 MORN, MORN repeat,score 36.3, E-value 7.5e-08 413999006812 Pfam match to entry PF02493 MORN, MORN repeat,score 27.9, E-value 2.6e-05 413999006813 Pfam match to entry PF02493 MORN, MORN repeat,score 35.9, E-value 9.8e-08 413999006814 Pfam match to entry PF02493 MORN, MORN repeat,score 38.3, E-value 1.8e-08 413999006815 Pfam match to entry PF02493 MORN, MORN repeat,score 34.4, E-value 2.8e-07 413999006816 Pfam match to entry PF02493 MORN, MORN repeat,score 32.4, E-value 1.1e-06 413999006817 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 413999006818 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803 413999006819 active site 413999006820 FMN binding site [chemical binding]; other site 413999006821 substrate binding site [chemical binding]; other site 413999006822 putative catalytic residue [active] 413999006823 Pfam match to entry PF00724 oxidored_FMN,NADH:flavin oxidoreductase / NADH oxidase, score 196.3, E-value 5e-56 413999006824 Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia. AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645 413999006825 dimer interface [polypeptide binding]; other site 413999006826 active site 413999006827 Pfam match to entry PF03590 AsnA, Aspartate-ammonia ligase, score 454.4, E-value 1e-133 413999006828 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 413999006829 Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723 413999006830 YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in...; Region: Rieske_YhfW_C; cd03477 413999006831 [2Fe-2S] cluster binding site [ion binding]; other site 413999006832 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain, score 59.6, E-value 6.9e-15 413999006833 PS00200 Rieske iron-sulfur protein signature 2. 413999006834 DNA topoisomerase III; Provisional; Region: PRK07726 413999006835 TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362 413999006836 active site 413999006837 putative interdomain interaction site [polypeptide binding]; other site 413999006838 putative metal-binding site [ion binding]; other site 413999006839 putative nucleotide binding site [chemical binding]; other site 413999006840 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986 413999006841 domain I; other site 413999006842 DNA binding groove [nucleotide binding] 413999006843 phosphate binding site [ion binding]; other site 413999006844 domain II; other site 413999006845 domain III; other site 413999006846 nucleotide binding site [chemical binding]; other site 413999006847 catalytic site [active] 413999006848 domain IV; other site 413999006849 Pfam match to entry PF01751 Toprim, Toprim domain,score 77.6, E-value 2.7e-20 413999006850 Pfam match to entry PF01131 Topoisom_bac, DNA topoisomerase, score 258.5, E-value 9.6e-75 413999006851 PS00396 Prokaryotic DNA topoisomerase I active site. 413999006852 ATP-binding cassette domain of MutS-like homolog; Region: ABC_MutS-like; cd03283 413999006853 Walker A/P-loop; other site 413999006854 ATP binding site [chemical binding]; other site 413999006855 Q-loop/lid; other site 413999006856 ABC transporter signature motif; other site 413999006857 Walker B; other site 413999006858 D-loop; other site 413999006859 H-loop/switch region; other site 413999006860 5 probable transmembrane helices predicted for CBO1507 by TMHMM2.0 at aa 21-43, 53-70, 211-233, 238-255 and 322-344 413999006861 Pfam match to entry PF00488 MutS_V, MutS domain V,score -31.5, E-value 6.2e-12 413999006862 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006863 Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453 413999006864 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 413999006865 active site 413999006866 catalytic tetrad [active] 413999006867 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999006868 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase, score 5.8, E-value 1.1e-09 413999006869 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 17.0, E-value 0.00053 413999006870 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999006871 This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335 413999006872 putative deacylase active site [active] 413999006873 Pfam match to entry PF04073 YbaK, YbaK / prolyl-tRNA synthetases associated domain, score 29.3,E-value 2.4e-07 413999006874 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999006875 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999006876 Walker A/P-loop; other site 413999006877 ATP binding site [chemical binding]; other site 413999006878 Q-loop/lid; other site 413999006879 ABC transporter signature motif; other site 413999006880 Walker B; other site 413999006881 D-loop; other site 413999006882 H-loop/switch region; other site 413999006883 Pfam match to entry PF00005 ABC_tran, ABC transporter score 189.0, E-value 8.1e-54 413999006884 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006885 PS00211 ABC transporters family signature. 413999006886 1 probable transmembrane helix predicted for CBO1511 by TMHMM2.0 at aa 17-39 413999006887 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006888 Pfam match to entry PF02687 FtsX, Predicted permease, score 67.7, E-value 2.6e-17 413999006889 6 probable transmembrane helices predicted for CBO1512 by TMHMM2.0 at aa 160-182, 210-232, 253-275,325-347, 529-551 and 612-634 413999006890 Pfam match to entry PF02687 FtsX, Predicted permease, score 25.3, E-value 6.9e-06 413999006891 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999006892 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999006893 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 67.6, E-value 2.7e-17 413999006894 PS01081 Bacterial regulatory proteins, tetR family signature. 413999006895 Protein of unknown function (DUF523); Region: DUF523; pfam04463 413999006896 ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839 413999006897 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 413999006898 Walker A/P-loop; other site 413999006899 ATP binding site [chemical binding]; other site 413999006900 Q-loop/lid; other site 413999006901 ABC transporter signature motif; other site 413999006902 Walker B; other site 413999006903 D-loop; other site 413999006904 H-loop/switch region; other site 413999006905 TOBE domain; Region: TOBE; pfam03459 413999006906 Pfam match to entry PF00005 ABC_tran, ABC transporter score 241.1, E-value 1.6e-69 413999006907 PS00017 ATP/GTP-binding site motif A (P-loop). 413999006908 PS00211 ABC transporters family signature. 413999006909 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 413999006910 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006911 dimer interface [polypeptide binding]; other site 413999006912 conserved gate region; other site 413999006913 putative PBP binding loops; other site 413999006914 ABC-ATPase subunit interface; other site 413999006915 6 probable transmembrane helices predicted for CBO1516 by TMHMM2.0 at aa 13-33, 75-97, 110-129, 163-185,206-228 and 263-285 413999006916 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 71.1, E-value 2.4e-18 413999006917 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 413999006918 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999006919 dimer interface [polypeptide binding]; other site 413999006920 conserved gate region; other site 413999006921 putative PBP binding loops; other site 413999006922 ABC-ATPase subunit interface; other site 413999006923 6 probable transmembrane helices predicted for CBO1517 by TMHMM2.0 at aa 9-31, 74-96, 105-127, 142-160,180-202 and 240-259 413999006924 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 77.0, E-value 4e-20 413999006925 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999006926 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 413999006927 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 413999006928 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 120.5, E-value 3.2e-33 413999006929 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999006930 PS00012 Phosphopantetheine attachment site. 413999006931 L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066 413999006932 A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292 413999006933 NAD binding site [chemical binding]; other site 413999006934 dimer interface [polypeptide binding]; other site 413999006935 substrate binding site [chemical binding]; other site 413999006936 tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999006937 Pfam match to entry PF02866 ldh_C, lactate/malate dehydrogenase, alpha/beta C-terminal domain, score 197.7,E-value 1.9e-56 413999006938 PS00064 L-lactate dehydrogenase active site. 413999006939 Pfam match to entry PF00056 ldh, lactate/malate dehydrogenase, NAD binding domain, score 251.4, E-value 1.3e-72 413999006940 1 probable transmembrane helix predicted for CBO1519 by TMHMM2.0 at aa 13-35 413999006941 Transcriptional regulators [Transcription]; Region: FadR; COG2186 413999006942 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999006943 DNA-binding site [nucleotide binding]; DNA binding site 413999006944 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 413999006945 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 82.5, E-value 8.9e-22 413999006946 PS00043 Bacterial regulatory proteins, gntR family signature. 413999006947 Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719 413999006948 C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325 413999006949 gating phenylalanine in ion channel; other site 413999006950 10 probable transmembrane helices predicted for CBO1522 by TMHMM2.0 at aa 10-29, 36-53, 68-85, 90-112,127-149, 156-175, 185-202, 214-233, 243-265 and 278-300 413999006951 Pfam match to entry PF03595 C4dic_mal_tran,C4-dicarboxylate transporter/malic acid transport protein,score -37.6, E-value 2.1e-08 413999006952 1 probable transmembrane helix predicted for CBO1523 by TMHMM2.0 at aa 27-49 413999006953 PAS domain S-box; Region: sensory_box; TIGR00229 413999006954 PAS domain; Region: PAS; smart00091 413999006955 putative active site [active] 413999006956 heme pocket [chemical binding]; other site 413999006957 PAS domain S-box; Region: sensory_box; TIGR00229 413999006958 PAS domain; Region: PAS_8; pfam13188 413999006959 putative active site [active] 413999006960 heme pocket [chemical binding]; other site 413999006961 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999006962 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999006963 metal binding site [ion binding]; metal-binding site 413999006964 active site 413999006965 I-site; other site 413999006966 c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206 413999006967 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999006968 Zn2+ binding site [ion binding]; other site 413999006969 Mg2+ binding site [ion binding]; other site 413999006970 2 probable transmembrane helices predicted for CBO1524 by TMHMM2.0 at aa 21-43 and 58-80 413999006971 Pfam match to entry PF00989 PAS, PAS domain, score 22.1, E-value 1.1e-05 413999006972 Pfam match to entry PF00989 PAS, PAS domain, score 16.0, E-value 0.0006 413999006973 Pfam match to entry PF00785 PAC, PAC motif, score 19.9, E-value 0.0061 413999006974 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 145.6, E-value 9.2e-41 413999006975 Pfam match to entry PF01966 HD, HD domain, score 97.4, E-value 2.9e-26 413999006976 Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026 413999006977 dimerization interface [polypeptide binding]; other site 413999006978 Pfam match to entry PF03860 DUF326, Domain of Unknown Function (DUF326), score 21.7, E-value 0.0018 413999006979 Pfam match to entry PF03860 DUF326, Domain of Unknown Function (DUF326), score 18.7, E-value 0.014 413999006980 Pfam match to entry PF03860 DUF326, Domain of Unknown Function (DUF326), score 24.9, E-value 0.0002 413999006981 Pfam match to entry PF03860 DUF326, Domain of Unknown Function (DUF326), score 24.5, E-value 0.00026 413999006982 Cache domain; Region: Cache_1; pfam02743 413999006983 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999006984 dimerization interface [polypeptide binding]; other site 413999006985 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999006986 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999006987 dimer interface [polypeptide binding]; other site 413999006988 putative CheW interface [polypeptide binding]; other site 413999006989 2 probable transmembrane helices predicted for CBO1526 by TMHMM2.0 at aa 10-32 and 306-328 413999006990 Pfam match to entry PF02743 Cache, Cache domain,score 46.3, E-value 7.1e-11 413999006991 Pfam match to entry PF00672 HAMP, HAMP domain,score 51.4, E-value 2.1e-12 413999006992 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 128.6, E-value 1.2e-35 413999006993 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999006994 MarR family; Region: MarR_2; pfam12802 413999006995 Pfam match to entry PF01047 MarR, MarR family,score 29.2, E-value 1e-05 413999006996 Flavodoxin domain; Region: Flavodoxin_5; pfam12724 413999006997 1 probable transmembrane helix predicted for CBO1528 by TMHMM2.0 at aa 47-66 413999006998 Predicted transcriptional regulators [Transcription]; Region: COG1733 413999006999 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 413999007000 Pfam match to entry PF01638 DUF24, Transcriptional regulator, score 195.6, E-value 7.9e-56 413999007001 1 probable transmembrane helix predicted for CBO1530 by TMHMM2.0 at aa 10-32 413999007002 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 413999007003 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 413999007004 active site 413999007005 metal binding site [ion binding]; metal-binding site 413999007006 Pfam match to entry PF00903 Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily, score 46.7, E-value 5.3e-11 413999007007 methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901 413999007008 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 413999007009 DNA binding site [nucleotide binding] 413999007010 active site 413999007011 Pfam match to entry PF01035 Methyltransf_1,6-O-methylguanine DNA methyltransferase, DNA binding domain, score 155.2, E-value 1.2e-43 413999007012 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 413999007013 TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; cl15424 413999007014 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999007015 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999007016 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999007017 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 35.9, E-value 9.8e-08 413999007018 Predicted helix-turn-helix motif with score 1832.000, SD 5.43 at aa 310-331, sequence ISFSDLAKVAHVSRSYLSTLFK 413999007019 PS00041 Bacterial regulatory proteins, araC family signature. 413999007020 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 41.3, E-value 2.2e-09 413999007021 hypothetical protein; Provisional; Region: PRK02399 413999007022 Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792 413999007023 TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; pfam09370 413999007024 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999007025 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999007026 non-specific DNA binding site [nucleotide binding]; other site 413999007027 salt bridge; other site 413999007028 sequence-specific DNA binding site [nucleotide binding]; other site 413999007029 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 60.6, E-value 3.5e-15 413999007030 Predicted helix-turn-helix motif with score 2124.000, SD 6.42 at aa 19-40, sequence ITQEQLANFVGVSTAAVSKWES 413999007031 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 413999007032 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474 413999007033 5 probable transmembrane helices predicted for CBO1537 by TMHMM2.0 at aa 20-42, 77-99, 109-128, 149-171 and 176-198 413999007034 Pfam match to entry PF00689 Cation_ATPase_C, Cation transporting ATPase, C-terminus, score 17.6, E-value 7.7e-06 413999007035 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 413999007036 cation diffusion facilitator family transporter; Region: CDF; TIGR01297 413999007037 3 probable transmembrane helices predicted for CBO1538 by TMHMM2.0 at aa 13-35, 82-104 and 117-134 413999007038 Pfam match to entry PF01545 Cation_efflux, Cation efflux family, score 306.1, E-value 4.3e-89 413999007039 Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104 413999007040 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999007041 putative substrate translocation pore; other site 413999007042 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -98.5, E-value 0.001 413999007043 12 probable transmembrane helices predicted for CBO1539 by TMHMM2.0 at aa 26-48, 58-77, 86-103, 108-125,149-171, 191-210, 244-262, 285-307, 328-350, 360-382,395-417 and 421-443 413999007044 Pfam match to entry PF00854 PTR2, POT family, score 45.1, E-value 1.4e-11 413999007045 Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325 413999007046 Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529 413999007047 Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742 413999007048 Predicted helix-turn-helix motif with score 1228.000, SD 3.37 at aa 22-43, sequence VRSIDIAKELNFSKPSVSHAVG 413999007049 Pfam match to entry PF02742 Fe_dep_repr_C, Iron dependent repressor, metal binding and dimerisation domain, score 26.0, E-value 9.3e-05 413999007050 HDOD domain; Region: HDOD; pfam08668 413999007051 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999007052 Zn2+ binding site [ion binding]; other site 413999007053 Mg2+ binding site [ion binding]; other site 413999007054 Pfam match to entry PF01966 HD, HD domain, score 42.7, E-value 8.5e-10 413999007055 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 413999007056 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474 413999007057 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 413999007058 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999007059 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 413999007060 haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710 413999007061 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 413999007062 Pfam match to entry PF00689 Cation_ATPase_C, Cation transporting ATPase, C-terminus, score 64.6, E-value 2.3e-16 413999007063 9 probable transmembrane helices predicted for CBO1545 by TMHMM2.0 at aa 59-93, 245-264, 274-296,670-692, 696-718, 741-763, 767-789, 810-827 and 842-864 413999007064 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 99.7, E-value 6e-27 413999007065 PS00154 E1-E2 ATPases phosphorylation site. 413999007066 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 329.8, E-value 3.3e-96 413999007067 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus, score 85.5, E-value 1.1e-22 413999007068 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 413999007069 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 413999007070 active site 413999007071 Pfam match to entry PF00903 Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily, score 35.5, E-value 1.3e-07 413999007072 PS00294 Prenyl group binding site (CAAX box). 413999007073 Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845 413999007074 Chloramphenicol acetyltransferase; Region: CAT; smart01059 413999007075 Pfam match to entry PF00302 CAT, Chloramphenicol acetyltransferase, score 64.0, E-value 4.4e-18 413999007076 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007077 DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402 413999007078 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 413999007079 ligand binding site [chemical binding]; other site 413999007080 flexible hinge region; other site 413999007081 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320 413999007082 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain, score 41.5, E-value 2e-09 413999007083 Predicted helix-turn-helix motif with score 1217.000, SD 3.33 at aa 178-199, sequence ENLTEIGELLGTSYRHLLRTLN 413999007084 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family, score 39.7, E-value 7.2e-09 413999007085 PS00622 Bacterial regulatory proteins, luxR family signature. 413999007086 Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674 413999007087 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708 413999007088 Predicted transcriptional regulator [Transcription]; Region: COG2378 413999007089 HTH domain; Region: HTH_11; pfam08279 413999007090 WYL domain; Region: WYL; pfam13280 413999007091 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family, score 18.6, E-value 2.1e-05 413999007092 Predicted helix-turn-helix motif with score 1872.000, SD 5.56 at aa 19-40, sequence ISASELAEKFEVSVRTIYRDIE 413999007093 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775 413999007094 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score -72.0, E-value 4e-08 413999007095 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999007096 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 8.4, E-value 5.1e-08 413999007097 Pfam match to entry PF01242 PTPS, 6-pyruvoyl tetrahydropterin synthase, score -13.3, E-value 4.2e-05 413999007098 6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242 413999007099 active site 413999007100 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, clostridial; Region: rSAM_QueE_Clost; TIGR03963 413999007101 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999007102 FeS/SAM binding site; other site 413999007103 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 53.3, E-value 5.5e-13 413999007104 GTP cyclohydrolase I; Provisional; Region: folE; PRK09347 413999007105 active site 413999007106 Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I, score 106.0, E-value 7.6e-29 413999007107 PS00859 GTP cyclohydrolase I signature 1. 413999007108 tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037 413999007109 ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995 413999007110 Ligand Binding Site [chemical binding]; other site 413999007111 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999007112 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999007113 dimer interface [polypeptide binding]; other site 413999007114 putative CheW interface [polypeptide binding]; other site 413999007115 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 77.0, E-value 4e-20 413999007116 Protein of unknown function (DUF975); Region: DUF975; cl10504 413999007117 Pfam match to entry PF06161 DUF975, Protein of unknown function (DUF975), score 97.6, E-value 2.5e-26 413999007118 4 probable transmembrane helices predicted for CBO1559 by TMHMM2.0 at aa 20-37, 69-91, 134-156 and 193-215 413999007119 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999007120 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 413999007121 MarR family; Region: MarR_2; pfam12802 413999007122 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 413999007123 Predicted helix-turn-helix motif with score 2219.000, SD 6.74 at aa 21-42, sequence YSQHEIANLLNISRPTVSKLLK 413999007124 Pfam match to entry PF04198 Sugar-bind, sugar-binding domain, score 282.4, E-value 6.2e-82 413999007125 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959 413999007126 intersubunit interface [polypeptide binding]; other site 413999007127 active site 413999007128 catalytic residue [active] 413999007129 Pfam match to entry PF01791 DeoC,Deoxyribose-phosphate aldolase, score 368.8, E-value 5.7e-108 413999007130 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 413999007131 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 413999007132 substrate binding site [chemical binding]; other site 413999007133 dimer interface [polypeptide binding]; other site 413999007134 ATP binding site [chemical binding]; other site 413999007135 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 256.2, E-value 4.6e-74 413999007136 ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292 413999007137 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 413999007138 dimer interface [polypeptide binding]; other site 413999007139 motif 1; other site 413999007140 active site 413999007141 motif 2; other site 413999007142 motif 3; other site 413999007143 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score -6.1, E-value 0.00012 413999007144 ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686 413999007145 ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040 413999007146 Pfam match to entry PF01634 HisG, ATP phosphoribosyltransferase, score 222.0, E-value 9e-64 413999007147 PS01316 ATP phosphoribosyltransferase signature. 413999007148 Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572 413999007149 histidinol dehydrogenase; Region: hisD; TIGR00069 413999007150 NAD binding site [chemical binding]; other site 413999007151 dimerization interface [polypeptide binding]; other site 413999007152 product binding site; other site 413999007153 substrate binding site [chemical binding]; other site 413999007154 zinc binding site [ion binding]; other site 413999007155 catalytic residues [active] 413999007156 Pfam match to entry PF00815 Histidinol_dh,Histidinol dehydrogenase, score 784.8, E-value 3.6e-233 413999007157 Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914 413999007158 putative active site pocket [active] 413999007159 4-fold oligomerization interface [polypeptide binding]; other site 413999007160 metal binding residues [ion binding]; metal-binding site 413999007161 3-fold/trimer interface [polypeptide binding]; other site 413999007162 Pfam match to entry PF00475 IGPD,Imidazoleglycerol-phosphate dehydratase, score 326.4,E-value 3.4e-95 413999007163 PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 413999007164 imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141 413999007165 Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748 413999007166 putative active site [active] 413999007167 oxyanion strand; other site 413999007168 catalytic triad [active] 413999007169 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I, score 146.2, E-value 6e-41 413999007170 PS00442 Glutamine amidotransferases class-I active site. 413999007171 HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732 413999007172 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007 413999007173 catalytic residues [active] 413999007174 Pfam match to entry PF00977 His_biosynth, Histidine biosynthesis protein, score 280.5, E-value 2.3e-81 413999007175 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079 413999007176 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999007177 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999007178 homodimer interface [polypeptide binding]; other site 413999007179 catalytic residue [active] 413999007180 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 120.1, E-value 4.4e-33 413999007181 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 413999007182 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999007183 The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731 413999007184 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 413999007185 substrate binding site [chemical binding]; other site 413999007186 glutamase interaction surface [polypeptide binding]; other site 413999007187 Pfam match to entry PF00977 His_biosynth, Histidine biosynthesis protein, score 463.7, E-value 1.6e-136 413999007188 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999007189 phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051 413999007190 Pfam match to entry PF01502 PRA-CH,Phosphoribosyl-AMP cyclohydrolase, score 186.7, E-value 3.9e-53 413999007191 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534 413999007192 metal binding site [ion binding]; metal-binding site 413999007193 Pfam match to entry PF01503 PRA-PH,Phosphoribosyl-ATP pyrophosphohydrolase, score 125.0,E-value 1.5e-34 413999007194 putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112 413999007195 6 probable transmembrane helices predicted for CBO1575 by TMHMM2.0 at aa 29-46, 51-65, 86-108, 130-152,159-176 and 199-221 413999007196 Pfam match to entry PF04143 DUF395, YeeE/YedE family (DUF395), score 52.1, E-value 1.3e-12 413999007197 SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291 413999007198 CPxP motif; other site 413999007199 Pfam match to entry PF01206 UPF0033,Uncharacterized protein family UPF0033, score 23.0,E-value 1.5e-06 413999007200 putative inner membrane protein; Provisional; Region: PRK11099 413999007201 4 probable transmembrane helices predicted for CBO1577 by TMHMM2.0 at aa 7-29, 65-84, 97-114 and 129-151 413999007202 Pfam match to entry PF04143 DUF395, YeeE/YedE family (DUF395), score 50.3, E-value 4.6e-12 413999007203 Transcriptional regulator [Transcription]; Region: LysR; COG0583 413999007204 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 413999007205 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 413999007206 dimerization interface [polypeptide binding]; other site 413999007207 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain, score 79.6, E-value 6.9e-21 413999007208 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 74.4, E-value 2.5e-19 413999007209 PS00044 Bacterial regulatory proteins, lysR family signature. 413999007210 Predicted helix-turn-helix motif with score 1474.000, SD 4.21 at aa 16-37, sequence NSISKAAEALHLTQPGLSMQLK 413999007211 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999007212 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 413999007213 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score -215.1, E-value 1.7e-06 413999007214 10 probable transmembrane helices predicted for CBO1579 by TMHMM2.0 at aa 38-60, 71-93, 113-135, 157-179,186-208, 223-245, 272-294, 328-350, 362-384 and 389-407 413999007215 CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385 413999007216 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999007217 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999007218 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 413999007219 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 413999007220 active site residue [active] 413999007221 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 263.6, E-value 2.7e-76 413999007222 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain,score 64.6, E-value 2.1e-16 413999007223 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 62.6, E-value 9e-16 413999007224 putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112 413999007225 Sulphur transport; Region: Sulf_transp; pfam04143 413999007226 PS00287 Cysteine proteases inhibitors signature. 413999007227 10 probable transmembrane helices predicted for CBO1581 by TMHMM2.0 at aa 7-24, 28-45, 66-88, 117-139,151-170, 190-209, 256-278, 330-348, 357-374 and 389-411 413999007228 Pfam match to entry PF04143 DUF395, YeeE/YedE family (DUF395), score 33.6, E-value 4.7e-07 413999007229 Pfam match to entry PF04143 DUF395, YeeE/YedE family (DUF395), score 59.0, E-value 1.1e-14 413999007230 gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740 413999007231 ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268 413999007232 Walker A/P-loop; other site 413999007233 ATP binding site [chemical binding]; other site 413999007234 Q-loop/lid; other site 413999007235 ABC transporter signature motif; other site 413999007236 Walker B; other site 413999007237 D-loop; other site 413999007238 H-loop/switch region; other site 413999007239 Pfam match to entry PF00005 ABC_tran, ABC transporter score 192.5, E-value 6.8e-55 413999007240 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007241 lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732 413999007242 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999007243 6 probable transmembrane helices predicted for CBO1583 by TMHMM2.0 at aa 20-39, 44-63, 94-116, 126-148,155-174 and 215-237 413999007244 lantibiotic protection ABC transporter permease subunit, MutG family; Region: lanti_perm_MutG; TIGR03733 413999007245 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999007246 6 probable transmembrane helices predicted for CBO1584 by TMHMM2.0 at aa 20-42, 52-74, 100-122, 127-149,156-178 and 218-240 413999007247 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999007248 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999007249 active site 413999007250 phosphorylation site [posttranslational modification] 413999007251 intermolecular recognition site; other site 413999007252 dimerization interface [polypeptide binding]; other site 413999007253 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999007254 DNA binding site [nucleotide binding] 413999007255 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 111.4, E-value 1.7e-30 413999007256 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 76.5, E-value 5.9e-20 413999007257 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999007258 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 413999007259 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999007260 dimer interface [polypeptide binding]; other site 413999007261 phosphorylation site [posttranslational modification] 413999007262 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999007263 ATP binding site [chemical binding]; other site 413999007264 Mg2+ binding site [ion binding]; other site 413999007265 G-X-G motif; other site 413999007266 2 probable transmembrane helices predicted for CBO1586 by TMHMM2.0 at aa 13-35 and 152-174 413999007267 Pfam match to entry PF00672 HAMP, HAMP domain,score 20.0, E-value 0.0058 413999007268 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 65.2, E-value 1.4e-16 413999007269 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 71.7,E-value 1.6e-18 413999007270 arginine deiminase; Provisional; Region: PRK01388 413999007271 N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834 413999007272 Pfam match to entry PF02274 Amidinotransf,Amidinotransferase, score 578.3, E-value 5.2e-171 413999007273 arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810 413999007274 12 probable transmembrane helices predicted for CBO1588 by TMHMM2.0 at aa 9-27, 42-64, 88-110, 125-142,154-176, 202-224, 237-259, 286-308, 329-351, 361-383,404-426 and 449-468 413999007275 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score -21.5, E-value 4.8e-07 413999007276 Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272 413999007277 channel protein, hemolysin III family; Region: hlyIII; TIGR01065 413999007278 6 probable transmembrane helices predicted for CBO1589 by TMHMM2.0 at aa 12-34, 39-61, 82-115, 130-149,156-178 and 193-215 413999007279 Pfam match to entry PF03006 UPF0073,Uncharacterised protein family (Hly-III / UPF0073), score 244.9, E-value 1.2e-70 413999007280 Domain of unknown function (DUF1836); Region: DUF1836; pfam08876 413999007281 HD domain; Region: HD_3; pfam13023 413999007282 Pfam match to entry PF01966 HD, HD domain, score 39.0, E-value 1.1e-08 413999007283 YmaF family; Region: YmaF; pfam12788 413999007284 Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455 413999007285 SNF2 family N-terminal domain; Region: SNF2_N; pfam00176 413999007286 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999007287 ATP binding site [chemical binding]; other site 413999007288 putative Mg++ binding site [ion binding]; other site 413999007289 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999007290 nucleotide binding region [chemical binding]; other site 413999007291 ATP-binding site [chemical binding]; other site 413999007292 Pfam match to entry PF04434 SWIM, SWIM zinc finger,score 13.9, E-value 0.021 413999007293 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007294 Pfam match to entry PF00176 SNF2_N, SNF2 family N-terminal domain, score 268.0, E-value 1.3e-77 413999007295 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 98.1, E-value 1.9e-26 413999007296 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 413999007297 synthetase active site [active] 413999007298 NTP binding site [chemical binding]; other site 413999007299 metal binding site [ion binding]; metal-binding site 413999007300 Pfam match to entry PF04607 RelA_SpoT, Region found in RelA / SpoT proteins, score 48.4, E-value 1.6e-11 413999007301 Domain of unknown function (DUF2383); Region: DUF2383; pfam09537 413999007302 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999007303 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999007304 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 17.2, E-value 0.028 413999007305 PS00041 Bacterial regulatory proteins, araC family signature. 413999007306 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 43.4, E-value 5.3e-10 413999007307 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999007308 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999007309 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999007310 Walker A/P-loop; other site 413999007311 ATP binding site [chemical binding]; other site 413999007312 Q-loop/lid; other site 413999007313 ABC transporter signature motif; other site 413999007314 Walker B; other site 413999007315 D-loop; other site 413999007316 H-loop/switch region; other site 413999007317 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 47.3, E-value 3.5e-11 413999007318 5 probable transmembrane helices predicted for CBO1599 by TMHMM2.0 at aa 21-43, 63-93, 141-158, 162-181 and 246-268 413999007319 Pfam match to entry PF00005 ABC_tran, ABC transporter score 187.2, E-value 2.7e-53 413999007320 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007321 PS00211 ABC transporters family signature. 413999007322 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999007323 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999007324 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999007325 Walker A/P-loop; other site 413999007326 ATP binding site [chemical binding]; other site 413999007327 Q-loop/lid; other site 413999007328 ABC transporter signature motif; other site 413999007329 Walker B; other site 413999007330 D-loop; other site 413999007331 H-loop/switch region; other site 413999007332 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 30.9, E-value 3e-06 413999007333 6 probable transmembrane helices predicted for CBO1600 by TMHMM2.0 at aa 20-42, 57-79, 136-153, 157-176,236-258 and 273-292 413999007334 Pfam match to entry PF00005 ABC_tran, ABC transporter score 233.4, E-value 3.4e-67 413999007335 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007336 PS00211 ABC transporters family signature. 413999007337 Transcriptional regulators [Transcription]; Region: PurR; COG1609 413999007338 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 413999007339 DNA binding site [nucleotide binding] 413999007340 domain linker motif; other site 413999007341 Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294 413999007342 putative dimerization interface [polypeptide binding]; other site 413999007343 putative ligand binding site [chemical binding]; other site 413999007344 Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score 47.5, E-value 3.2e-11 413999007345 Predicted helix-turn-helix motif with score 2338.000, SD 7.15 at aa 3-24, sequence VTIKDVAKEAKVSPSTVSRVLS 413999007346 PS00356 Bacterial regulatory proteins, lacI family signature. 413999007347 Pfam match to entry PF00532 Peripla_BP_like,Periplasmic binding proteins and sugar binding domain of the LacI family, score 80.2, E-value 4.5e-21 413999007348 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 413999007349 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 413999007350 nucleotide binding site [chemical binding]; other site 413999007351 Pfam match to entry PF00480 ROK, ROK family, score 193.7, E-value 3e-55 413999007352 alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403 413999007353 Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333 413999007354 Ca binding site [ion binding]; other site 413999007355 active site 413999007356 catalytic site [active] 413999007357 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain, score 407.9, E-value 1e-119 413999007358 PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003 413999007359 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999007360 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999007361 active site turn [active] 413999007362 phosphorylation site [posttranslational modification] 413999007363 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 138.2, E-value 1.5e-38 413999007364 9 probable transmembrane helices predicted for CBO1605 by TMHMM2.0 at aa 21-43, 58-77, 84-106, 137-159,180-202, 310-328, 341-363, 373-395 and 416-438 413999007365 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 56.0, E-value 8.4e-14 413999007366 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999007367 Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079 413999007368 putative catalytic site [active] 413999007369 putative metal binding site [ion binding]; other site 413999007370 putative phosphate binding site [ion binding]; other site 413999007371 Pfam match to entry PF03372 Exo_endo_phos,Endonuclease/Exonuclease/phosphatase, score 80.6,E-value 3.4e-21 413999007372 putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840 413999007373 Domain of unknown function DUF; Region: DUF204; pfam02659 413999007374 5 probable transmembrane helices predicted for CBO1607 by TMHMM2.0 at aa 5-24, 29-51, 58-80, 157-179 and 188-206 413999007375 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323 413999007376 Domain of unknown function (DUF3794); Region: DUF3794; pfam12673 413999007377 PS00430 TonB-dependent receptor proteins signature 1. 413999007378 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999007379 dimerization interface [polypeptide binding]; other site 413999007380 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999007381 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999007382 dimer interface [polypeptide binding]; other site 413999007383 phosphorylation site [posttranslational modification] 413999007384 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999007385 ATP binding site [chemical binding]; other site 413999007386 Mg2+ binding site [ion binding]; other site 413999007387 G-X-G motif; other site 413999007388 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 36.0,E-value 9.2e-08 413999007389 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 74.7, E-value 2e-19 413999007390 Pfam match to entry PF00672 HAMP, HAMP domain,score 19.0, E-value 0.012 413999007391 6 probable transmembrane helices predicted for CBO1612 by TMHMM2.0 at aa 9-31, 265-282, 307-329, 333-355,395-417 and 422-441 413999007392 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999007393 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999007394 active site 413999007395 phosphorylation site [posttranslational modification] 413999007396 intermolecular recognition site; other site 413999007397 dimerization interface [polypeptide binding]; other site 413999007398 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999007399 DNA binding site [nucleotide binding] 413999007400 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 90.0, E-value 4.9e-24 413999007401 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 133.3, E-value 4.5e-37 413999007402 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999007403 oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890 413999007404 putative substrate translocation pore; other site 413999007405 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -112.1, E-value 0.0027 413999007406 11 probable transmembrane helices predicted for CBO1614 by TMHMM2.0 at aa 10-32, 45-62, 72-91, 96-118,133-155, 160-182, 222-241, 248-270, 304-326, 338-360 and 370-392 413999007407 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999007408 haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282 413999007409 active site 413999007410 motif I; other site 413999007411 motif II; other site 413999007412 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999007413 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 28.5, E-value 1.6e-05 413999007414 PS01229 Hypothetical cof family signature 2. 413999007415 PS01228 Hypothetical cof family signature 1. 413999007416 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 413999007417 helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420 413999007418 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 413999007419 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family, score 225.0, E-value 1.1e-64 413999007420 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 413999007421 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999007422 DNA binding residues [nucleotide binding] 413999007423 YvrJ protein family; Region: YvrJ; pfam12841 413999007424 Peptidase family M9 N-terminal; Region: Peptidase_M9_N; pfam08453 413999007425 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 413999007426 polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146 413999007427 Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151 413999007428 Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151 413999007429 Pfam match to entry PF04151 PPC, Bacterial pre-peptidase C-terminal domain, score 51.5, E-value 1.9e-12 413999007430 Pfam match to entry PF00801 PKD, PKD domain, score 83.7, E-value 3.9e-22 413999007431 Pfam match to entry PF01752 Peptidase_M9,Collagenase, score 331.3, E-value 1.1e-96 413999007432 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999007433 Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537 413999007434 FAD binding site [chemical binding]; other site 413999007435 Pfam match to entry PF02219 MTHFR,Methylenetetrahydrofolate reductase, score 278.4, E-value 9.8e-81 413999007436 Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965 413999007437 Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105 413999007438 Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574 413999007439 Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH). DHPS, a...; Region: Pterin_binding; cl00219 413999007440 substrate binding pocket [chemical binding]; other site 413999007441 dimer interface [polypeptide binding]; other site 413999007442 inhibitor binding site; inhibition site 413999007443 B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293 413999007444 methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370 413999007445 B12 binding site [chemical binding]; other site 413999007446 Pfam match to entry PF02574 S-methyl_trans,Homocysteine S-methyltransferase, score 156.3, E-value 5.6e-44 413999007447 Pfam match to entry PF00809 Pterin_bind, Pterin binding enzyme, score 135.4, E-value 1.1e-37 413999007448 Pfam match to entry PF02607 B12-binding_2, B12 binding domain, score 41.7, E-value 1.8e-09 413999007449 Pfam match to entry PF02310 B12-binding, B12 binding domain, score 113.3, E-value 4.8e-31 413999007450 RNA polymerase factor sigma-70; Validated; Region: PRK06811 413999007451 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 413999007452 DNA binding residues [nucleotide binding] 413999007453 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 21.5, E-value 0.001 413999007454 Domain of unknown function (DUF4179); Region: DUF4179; pfam13786 413999007455 1 probable transmembrane helix predicted for CBO1626 by TMHMM2.0 at aa 61-80 413999007456 DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388 413999007457 GAF domain; Region: GAF; pfam01590 413999007458 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999007459 Walker A motif; other site 413999007460 ATP binding site [chemical binding]; other site 413999007461 Walker B motif; other site 413999007462 arginine finger; other site 413999007463 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999007464 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 417.9, E-value 9.7e-123 413999007465 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999007466 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999007467 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999007468 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 62.4, E-value 1e-15 413999007469 Predicted helix-turn-helix motif with score 1024.000, SD 2.67 at aa 617-638, sequence GNVVNASKIIGIGKSTLYRKIE 413999007470 Conserved hypothetical protein (Lin0512_fam); Region: Lin0512_fam; cl09807 413999007471 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071 413999007472 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 413999007473 tetramer interface [polypeptide binding]; other site 413999007474 TPP-binding site [chemical binding]; other site 413999007475 heterodimer interface [polypeptide binding]; other site 413999007476 phosphorylation loop region [posttranslational modification] 413999007477 Pfam match to entry PF00676 E1_dehydrog,Dehydrogenase E1 component, score 472.7, E-value 3e-139 413999007478 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 413999007479 Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036 413999007480 alpha subunit interface [polypeptide binding]; other site 413999007481 TPP binding site [chemical binding]; other site 413999007482 heterodimer interface [polypeptide binding]; other site 413999007483 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 413999007484 Pfam match to entry PF02779 transket_pyr,Transketolase, pyridine binding domain, score 260.8,E-value 1.9e-75 413999007485 Pfam match to entry PF02780 transketolase_C,Transketolase, C-terminal domain, score 201.9, E-value 1.1e-57 413999007486 Predicted inorganic polyphosphate/ATP-NAD kinase [General function prediction only]; Region: COG3199 413999007487 Pfam match to entry PF01513 NAD_kinase, ATP-NAD kinase, score 200.7, E-value 2.4e-57 413999007488 branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856 413999007489 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 413999007490 E3 interaction surface; other site 413999007491 lipoyl attachment site [posttranslational modification]; other site 413999007492 e3 binding domain; Region: E3_binding; pfam02817 413999007493 e3 binding domain; Region: E3_binding; pfam02817 413999007494 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 413999007495 Pfam match to entry PF00364 biotin_lipoyl,Biotin-requiring enzyme, score 65.8, E-value 9.8e-17 413999007496 Pfam match to entry PF02817 e3_binding, e3 binding domain, score 57.3, E-value 3.4e-14 413999007497 Pfam match to entry PF02817 e3_binding, e3 binding domain, score 28.5, E-value 1.6e-05 413999007498 Pfam match to entry PF00198 2-oxoacid_dh, 2-oxoacid dehydrogenases acyltransferase (catalytic domain), score 377.9, E-value 1.1e-110 413999007499 dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350 413999007500 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999007501 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999007502 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 413999007503 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 352.0, E-value 6.8e-103 413999007504 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 413999007505 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain,score 205.1, E-value 1.1e-58 413999007506 lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545 413999007507 Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095 413999007508 Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437 413999007509 Pfam match to entry PF03099 BPL_LipA_LipB,Biotin/lipoate A/B protein ligase, score 132.2,E-value 1e-36 413999007510 ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125 413999007511 ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295 413999007512 Walker A/P-loop; other site 413999007513 ATP binding site [chemical binding]; other site 413999007514 Q-loop/lid; other site 413999007515 ABC transporter signature motif; other site 413999007516 Walker B; other site 413999007517 D-loop; other site 413999007518 H-loop/switch region; other site 413999007519 FOG: CBS domain [General function prediction only]; Region: COG0517 413999007520 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583 413999007521 Pfam match to entry PF00005 ABC_tran, ABC transporter score 231.3, E-value 1.5e-66 413999007522 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007523 PS00211 ABC transporters family signature. 413999007524 Pfam match to entry PF00571 CBS, CBS domain, score 47.2, E-value 3.9e-11 413999007525 Pfam match to entry PF00571 CBS, CBS domain, score 44.9, E-value 1.9e-10 413999007526 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999007527 ABC-ATPase subunit interface; other site 413999007528 Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069 413999007529 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 113.0, E-value 5.9e-31 413999007530 6 probable transmembrane helices predicted for CBO1637 by TMHMM2.0 at aa 24-46, 53-75, 79-98, 148-170,180-202 and 234-256 413999007531 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999007532 Pfam match to entry PF04069 OpuAC, Substrate binding domain of ABC-type glycine betaine transport system, score 306.8, E-value 2.7e-89 413999007533 Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498 413999007534 Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560 413999007535 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999007536 catalytic residue [active] 413999007537 Pfam match to entry PF00291 PALP,Pyridoxal-phosphate dependent enzyme, score 11.0, E-value 5.4e-08 413999007538 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 413999007539 homoserine kinase; Provisional; Region: PRK01212 413999007540 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 413999007541 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein, score 136.0, E-value 7.2e-38 413999007542 PS00627 GHMP kinases ATP-binding domain. 413999007543 aspartate kinase; Reviewed; Region: PRK09034 413999007544 Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452 413999007545 nucleotide binding site [chemical binding]; other site 413999007546 substrate binding site [chemical binding]; other site 413999007547 ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911 413999007548 allosteric regulatory residue; other site 413999007549 ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916 413999007550 Pfam match to entry PF00696 aakinase, Amino acid kinase, score 97.8, E-value 2.3e-26 413999007551 PS00324 Aspartokinase signature. 413999007552 Pfam match to entry PF01842 ACT, ACT domain, score 20.1, E-value 5.4e-05 413999007553 homoserine dehydrogenase; Provisional; Region: PRK06349 413999007554 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 413999007555 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 413999007556 ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881 413999007557 Pfam match to entry PF03447 NAD_binding_3,Homoserine dehydrogenase, NAD binding domain, score 158.7,E-value 1e-44 413999007558 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 413999007559 Pfam match to entry PF00742 Homoserine_dh,Homoserine dehydrogenase, score 299.8, E-value 3.4e-87 413999007560 PS01042 Homoserine dehydrogenase signature. 413999007561 Pfam match to entry PF01842 ACT, ACT domain, score 50.9, E-value 2.9e-12 413999007562 Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284 413999007563 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999007564 putative active site [active] 413999007565 heme pocket [chemical binding]; other site 413999007566 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999007567 Walker A motif; other site 413999007568 ATP binding site [chemical binding]; other site 413999007569 Walker B motif; other site 413999007570 arginine finger; other site 413999007571 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999007572 Pfam match to entry PF00989 PAS, PAS domain, score 25.0, E-value 1.6e-06 413999007573 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 444.4, E-value 1e-130 413999007574 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999007575 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999007576 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999007577 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 54.1, E-value 3.2e-13 413999007578 Predicted helix-turn-helix motif with score 1628.000, SD 4.73 at aa 611-632, sequence SNMSQSAKALGITRATLYSKLK 413999007579 Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454 413999007580 NADPH-dependent butanol dehydrogenase involved in the butanol and ethanol formation pathway in bacteria; Region: NADPH_BDH; cd08179 413999007581 putative active site [active] 413999007582 metal binding site [ion binding]; metal-binding site 413999007583 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 590.4, E-value 1.1e-174 413999007584 PS00913 Iron-containing alcohol dehydrogenases signature 1. 413999007585 PS00060 Iron-containing alcohol dehydrogenases signature 2. 413999007586 ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222 413999007587 FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219 413999007588 FAD binding pocket [chemical binding]; other site 413999007589 FAD binding motif [chemical binding]; other site 413999007590 phosphate binding motif [ion binding]; other site 413999007591 beta-alpha-beta structure motif; other site 413999007592 NAD binding pocket [chemical binding]; other site 413999007593 Iron coordination center [ion binding]; other site 413999007594 putative oxidoreductase; Provisional; Region: PRK12831 413999007595 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999007596 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 110.5, E-value 3.4e-30 413999007597 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 372.5, E-value 4.7e-109 413999007598 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999007599 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999007600 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999007601 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 67.6, E-value 2.8e-17 413999007602 Predicted helix-turn-helix motif with score 2046.000, SD 6.16 at aa 617-638, sequence GNLAKAARLLDIGRSTLYRKIK 413999007603 prophage remnant 413999007604 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 413999007605 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 413999007606 Pfam match to entry PF00805 Pentapeptide,Pentapeptide repeats (8 copies), score 14.2, E-value 0.13 413999007607 Pfam match to entry PF00805 Pentapeptide,Pentapeptide repeats (8 copies), score 36.8, E-value 5.1e-08 413999007608 Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492 413999007609 Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368 413999007610 Pfam match to entry PF02368 Big_2, Bacterial Ig-like domain (group 2), score 84.8, E-value 1.9e-22 413999007611 1 probable transmembrane helix predicted for CBO1651 by TMHMM2.0 at aa 7-29 413999007612 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999007613 Domain of unknown function (DUF1508); Region: DUF1508; cl01356 413999007614 Domain of unknown function (DUF4352); Region: DUF4352; pfam11611 413999007615 1 probable transmembrane helix predicted for CBO1656 by TMHMM2.0 at aa 13-30 413999007616 Hemerythrin-like domain; Region: Hr-like; cd12108 413999007617 Fe binding site [ion binding]; other site 413999007618 Pfam match to entry PF03794 HHE, Domain of Unknown function, score 38.7, E-value 1.4e-08 413999007619 Pfam match to entry PF03794 HHE, Domain of Unknown function, score 45.9, E-value 9.5e-11 413999007620 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999007621 alanine racemase; Reviewed; Region: alr; PRK00053 413999007622 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430 413999007623 active site 413999007624 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999007625 dimer interface [polypeptide binding]; other site 413999007626 substrate binding site [chemical binding]; other site 413999007627 catalytic residues [active] 413999007628 Pfam match to entry PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain, score 262.2, E-value 7.5e-76 413999007629 PS00395 Alanine racemase pyridoxal-phosphate attachment site. 413999007630 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 413999007631 Pfam match to entry PF00842 Ala_racemase_C, Alanine racemase, C-terminal domain, score 205.4, E-value 9.4e-59 413999007632 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999007633 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999007634 dimer interface [polypeptide binding]; other site 413999007635 putative CheW interface [polypeptide binding]; other site 413999007636 MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682 413999007637 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 26.9, E-value 4.6e-09 413999007638 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 413999007639 Pfam match to entry PF00860 xan_ur_permease,Permease, score -4.4, E-value 1.9e-09 413999007640 13 probable transmembrane helices predicted for CBO1662 by TMHMM2.0 at aa 20-42, 52-71, 76-98, 103-123,136-158, 173-190, 197-214, 243-265, 285-304, 319-338,345-367, 377-399 and 412-431 413999007641 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999007642 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007643 Protein of unknown function (DUF975); Region: DUF975; cl10504 413999007644 Pfam match to entry PF06161 DUF975, Protein of unknown function (DUF975), score 160.6, E-value 2.7e-45 413999007645 5 probable transmembrane helices predicted for CBO1663 by TMHMM2.0 at aa 23-45, 65-87, 123-145, 165-187 and 222-244 413999007646 short chain dehydrogenase; Provisional; Region: PRK06701 413999007647 classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355 413999007648 NAD binding site [chemical binding]; other site 413999007649 metal binding site [ion binding]; metal-binding site 413999007650 active site 413999007651 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 226.5, E-value 4e-65 413999007652 PS00061 Short-chain dehydrogenases/reductases family signature. 413999007653 1 probable transmembrane helix predicted for CBO1665 by TMHMM2.0 at aa 4-26 413999007654 Cache domain; Region: Cache_1; pfam02743 413999007655 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999007656 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999007657 dimer interface [polypeptide binding]; other site 413999007658 putative CheW interface [polypeptide binding]; other site 413999007659 2 probable transmembrane helices predicted for CBO1666 by TMHMM2.0 at aa 10-32 and 283-305 413999007660 Pfam match to entry PF02743 Cache, Cache domain,score 53.3, E-value 5.4e-13 413999007661 Pfam match to entry PF00672 HAMP, HAMP domain,score 29.4, E-value 9e-06 413999007662 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 121.7, E-value 1.4e-33 413999007663 KWG Leptospira; Region: KWG; pfam07656 413999007664 KWG Leptospira; Region: KWG; pfam07656 413999007665 Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455 413999007666 SNF2 family N-terminal domain; Region: SNF2_N; pfam00176 413999007667 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999007668 ATP binding site [chemical binding]; other site 413999007669 putative Mg++ binding site [ion binding]; other site 413999007670 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999007671 nucleotide binding region [chemical binding]; other site 413999007672 ATP-binding site [chemical binding]; other site 413999007673 Pfam match to entry PF04434 SWIM, SWIM zinc finger,score 21.2, E-value 0.0025 413999007674 Pfam match to entry PF00176 SNF2_N, SNF2 family N-terminal domain, score 292.8, E-value 4.6e-85 413999007675 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 101.1, E-value 2.3e-27 413999007676 Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281 413999007677 homodimer interaction site [polypeptide binding]; other site 413999007678 cofactor binding site; other site 413999007679 Pfam match to entry PF01980 UPF0066,Uncharacterised protein family UPF0066, score 86.1,E-value 7.7e-23 413999007680 PS01318 Uncharacterized protein family UPF0066 signature. 413999007681 Formylmethanofuran dehydrogenase subunit E [Energy production and conversion]; Region: COG2191 413999007682 FmdE, Molybdenum formylmethanofuran dehydrogenase operon; Region: FmdE; pfam02663 413999007683 Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; pfam01258 413999007684 Pfam match to entry PF02663 FwdE, Tungsten formylmethanofuran dehydrogenase, subunit E, FwdE, score 121.1, E-value 2.2e-33 413999007685 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 413999007686 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_21; cd08520 413999007687 1 probable transmembrane helix predicted for CBO1675 by TMHMM2.0 at aa 9-26 413999007688 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999007689 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, score 97.5, E-value 2.9e-26 413999007690 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 413999007691 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 413999007692 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999007693 putative PBP binding loops; other site 413999007694 dimer interface [polypeptide binding]; other site 413999007695 ABC-ATPase subunit interface; other site 413999007696 6 probable transmembrane helices predicted for CBO1676 by TMHMM2.0 at aa 7-29, 102-124, 137-159, 189-211,251-273 and 293-312 413999007697 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 189.3, E-value 6.5e-54 413999007698 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 413999007699 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999007700 dimer interface [polypeptide binding]; other site 413999007701 conserved gate region; other site 413999007702 putative PBP binding loops; other site 413999007703 ABC-ATPase subunit interface; other site 413999007704 PS00443 Glutamine amidotransferases class-II active site. 413999007705 4 probable transmembrane helices predicted for CBO1677 by TMHMM2.0 at aa 13-35, 82-104, 116-135 and 244-266 413999007706 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 103.5, E-value 4.2e-28 413999007707 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 413999007708 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 413999007709 Walker A/P-loop; other site 413999007710 ATP binding site [chemical binding]; other site 413999007711 Q-loop/lid; other site 413999007712 ABC transporter signature motif; other site 413999007713 Walker B; other site 413999007714 D-loop; other site 413999007715 H-loop/switch region; other site 413999007716 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 413999007717 Pfam match to entry PF00005 ABC_tran, ABC transporter score 186.2, E-value 5.6e-53 413999007718 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007719 PS00211 ABC transporters family signature. 413999007720 prophage 413999007721 phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189 413999007722 Int/Topo IB signature motif; other site 413999007723 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score 106.4, E-value 5.8e-29 413999007724 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999007725 non-specific DNA binding site [nucleotide binding]; other site 413999007726 salt bridge; other site 413999007727 sequence-specific DNA binding site [nucleotide binding]; other site 413999007728 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999007729 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999007730 non-specific DNA binding site [nucleotide binding]; other site 413999007731 salt bridge; other site 413999007732 sequence-specific DNA binding site [nucleotide binding]; other site 413999007733 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 66.1, E-value 7.9e-17 413999007734 Predicted helix-turn-helix motif with score 2200.000, SD 6.68 at aa 16-37, sequence MTQEEYAKLIGITRGTLSHLER 413999007735 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999007736 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999007737 non-specific DNA binding site [nucleotide binding]; other site 413999007738 salt bridge; other site 413999007739 sequence-specific DNA binding site [nucleotide binding]; other site 413999007740 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 50.6, E-value 3.6e-12 413999007741 Predicted helix-turn-helix motif with score 1503.000, SD 4.31 at aa 16-37, sequence MTQKEFAKLLETDRGSIAHYEN 413999007742 Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669 413999007743 ORF6C domain; Region: ORF6C; pfam10552 413999007744 Predicted helix-turn-helix motif with score 1473.000, SD 4.20 at aa 5-26, sequence YKAKEVAKILDISVTQSYRIIK 413999007745 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393 413999007746 Predicted helix-turn-helix motif with score 1567.000, SD 4.52 at aa 75-96, sequence LKFKEIAEIFCLDPSTVCTLVN 413999007747 Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; pfam07352 413999007748 ERF superfamily; Region: ERF; pfam04404 413999007749 Pfam match to entry PF04404 ERF, ERF superfamily,score 122.5, E-value 8.1e-34 413999007750 N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; pfam09681 413999007751 DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484 413999007752 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999007753 Walker A motif; other site 413999007754 ATP binding site [chemical binding]; other site 413999007755 Walker B motif; other site 413999007756 Pfam match to entry PF01695 IstB, IstB-like ATP binding protein, score 25.8, E-value 8.2e-08 413999007757 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007758 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u2; cd11539 413999007759 metal binding site [ion binding]; metal-binding site 413999007760 DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442 413999007761 Pfam match to entry PF05869 Dam, DNA N-6-adenine-methyltransferase (Dam), score 69.9, E-value 5.6e-18 413999007762 PS00092 N-6 Adenine-specific DNA methylases signature. 413999007763 putative alcohol dehydrogenase; Provisional; Region: PRK13771 413999007764 Domain of unknown function (DUF4406); Region: DUF4406; pfam14359 413999007765 Protein of unknown function (DUF968); Region: DUF968; pfam06147 413999007766 Predicted helix-turn-helix motif with score 1060.000, SD 2.80 at aa 18-39, sequence YGMEEIKDRLGISTNAVKSLSK 413999007767 Endodeoxyribonuclease RusA; Region: RusA; pfam05866 413999007768 Pfam match to entry PF05866 RusA,Endodeoxyribonuclease RusA, score 102.7, E-value 7.6e-28 413999007769 YopX protein; Region: YopX; pfam09643 413999007770 PS00228 Tubulin-beta mRNA autoregulation signal. 413999007771 Predicted helix-turn-helix motif with score 1364.000, SD 3.83 at aa 32-53, sequence LTDLQIAIRMKMSQSQLKIQKK 413999007772 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 413999007773 Predicted helix-turn-helix motif with score 1368.000, SD 3.85 at aa 136-157, sequence LGIEQISDQLNMSRATGYKKRE 413999007774 2 probable transmembrane helices predicted for CBO1718 by TMHMM2.0 at aa 15-34 and 41-60 413999007775 1 probable transmembrane helix predicted for CBO1720 by TMHMM2.0 at aa 4-26 413999007776 Terminase small subunit; Region: Terminase_2; pfam03592 413999007777 Pfam match to entry PF03592 Terminase_2, Terminase small subunit, score 196.9, E-value 3.3e-56 413999007778 Phage terminase large subunit; Region: Terminase_3; cl12054 413999007779 Terminase-like family; Region: Terminase_6; pfam03237 413999007780 Pfam match to entry PF04466 Terminase_3, Phage terminase large subunit, score 240.1, E-value 3.2e-69 413999007781 Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133 413999007782 phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538 413999007783 Pfam match to entry PF05133 Phage_prot_Gp6, Phage portal protein, SPP1 Gp6-like, score 225.4, E-value 8.8e-65 413999007784 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999007785 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 413999007786 Pfam match to entry PF04233 Phage_Mu_F, Phage Mu protein F like protein, score 77.5, E-value 2.9e-20 413999007787 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999007788 2 probable transmembrane helices predicted for CBO1726 by TMHMM2.0 at aa 4-26 and 46-68 413999007789 Phage minor structural protein GP20; Region: Phage_GP20; pfam06810 413999007790 Head-Tail Connector Protein gp15 of Bacteriophage SPP1 and similar proteins; Region: gp15; cd08055 413999007791 Phage tail sheath protein; Region: Phage_sheath_1; pfam04984 413999007792 Protein of unknown function (DUF2001); Region: DUF2001; pfam09393 413999007793 Phage XkdN-like protein; Region: XkdN; pfam08890 413999007794 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999007795 4 probable transmembrane helices predicted for CBO1737 by TMHMM2.0 at aa 347-369, 376-398, 413-435 and 447-469 413999007796 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999007797 Pfam match to entry PF01476 LysM, LysM domain,score 41.1, E-value 2.6e-09 413999007798 Protein of unknown function (DUF2577); Region: DUF2577; pfam10844 413999007799 Protein of unknown function (DUF2634); Region: DUF2634; pfam10934 413999007800 Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299 413999007801 Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542 413999007802 Phage tail-collar fibre protein; Region: DUF3751; pfam12571 413999007803 6 probable transmembrane helices predicted for CBO1748 by TMHMM2.0 at aa 10-28, 41-63, 83-105, 117-135,140-159 and 193-215 413999007804 Haemolysin XhlA; Region: XhlA; pfam10779 413999007805 1 probable transmembrane helix predicted for CBO1749 by TMHMM2.0 at aa 53-71 413999007806 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999007807 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999007808 active site 413999007809 metal binding site [ion binding]; metal-binding site 413999007810 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999007811 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 71.2, E-value 2.2e-18 413999007812 1 probable transmembrane helix predicted for CBO1752 by TMHMM2.0 at aa 4-26 413999007813 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999007814 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 413999007815 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 413999007816 Walker A/P-loop; other site 413999007817 ATP binding site [chemical binding]; other site 413999007818 Q-loop/lid; other site 413999007819 ABC transporter signature motif; other site 413999007820 Walker B; other site 413999007821 D-loop; other site 413999007822 H-loop/switch region; other site 413999007823 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.6, E-value 3.2e-55 413999007824 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007825 PS00211 ABC transporters family signature. 413999007826 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 413999007827 active site 413999007828 catalytic site [active] 413999007829 substrate binding site [chemical binding]; other site 413999007830 Pfam match to entry PF00929 Exonuclease,Exonuclease, score 15.9, E-value 2.9e-06 413999007831 Predicted secreted protein [Function unknown]; Region: COG4086 413999007832 Protein of unknown function (DUF1002); Region: DUF1002; pfam06207 413999007833 1 probable transmembrane helix predicted for CBO1758 by TMHMM2.0 at aa 7-26 413999007834 Pfam match to entry PF06207 DUF1002, Protein of unknown function (DUF1002), score 360.6, E-value 1.7e-105 413999007835 Methyltransferase domain; Region: Methyltransf_31; pfam13847 413999007836 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999007837 S-adenosylmethionine binding site [chemical binding]; other site 413999007838 Pfam match to entry PF01209 Ubie_methyltran,ubiE/COQ5 methyltransferase, score -106.3, E-value 1.4e-05 413999007839 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 413999007840 Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471 413999007841 putative dimer interface [polypeptide binding]; other site 413999007842 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family, score 108.6, E-value 1.3e-29 413999007843 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999007844 Major Facilitator Superfamily; Region: MFS_1; pfam07690 413999007845 putative substrate translocation pore; other site 413999007846 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -96.7, E-value 0.00088 413999007847 12 probable transmembrane helices predicted for CBO1761 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 102-124,137-159, 164-186, 222-244, 254-276, 283-302, 312-334,347-369 and 374-393 413999007848 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999007849 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999007850 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 28.1, E-value 2.2e-05 413999007851 Predicted helix-turn-helix motif with score 1405.000, SD 3.97 at aa 21-42, sequence FTMDDISYDLKISKKTIYKYFK 413999007852 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105 413999007853 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 413999007854 putative substrate binding site [chemical binding]; other site 413999007855 putative ATP binding site [chemical binding]; other site 413999007856 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 123.0, E-value 5.7e-34 413999007857 PS00584 pfkB family of carbohydrate kinases signature 2. 413999007858 Major Facilitator Superfamily; Region: MFS_1; pfam07690 413999007859 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999007860 putative substrate translocation pore; other site 413999007861 12 probable transmembrane helices predicted for CBO1764 by TMHMM2.0 at aa 21-43, 53-75, 80-102, 112-134,146-168, 188-207, 249-271, 291-313, 330-352, 362-384,391-410 and 425-447 413999007862 Pfam match to entry PF00854 PTR2, POT family, score 24.6, E-value 1.6e-10 413999007863 Putative amidase domain; Region: Amidase_6; pfam12671 413999007864 YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941 413999007865 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 413999007866 substrate binding site [chemical binding]; other site 413999007867 ATP binding site [chemical binding]; other site 413999007868 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 134.4, E-value 2.1e-37 413999007869 PS00584 pfkB family of carbohydrate kinases signature 2. 413999007870 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999007871 Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340 413999007872 SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379 413999007873 Pfam match to entry PF00188 SCP, SCP-like extracellular protein, score 20.4, E-value 4.9e-05 413999007874 Pfam match to entry PF01476 LysM, LysM domain,score 59.6, E-value 6.8e-15 413999007875 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 413999007876 DNA-binding site [nucleotide binding]; DNA binding site 413999007877 RNA-binding motif; other site 413999007878 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain, score 95.5, E-value 1.1e-25 413999007879 Cache domain; Region: Cache_1; pfam02743 413999007880 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 413999007881 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999007882 dimer interface [polypeptide binding]; other site 413999007883 putative CheW interface [polypeptide binding]; other site 413999007884 2 probable transmembrane helices predicted for CBO1773 by TMHMM2.0 at aa 10-32 and 286-308 413999007885 Pfam match to entry PF02743 Cache, Cache domain,score 42.7, E-value 8.6e-10 413999007886 PS00135 Serine proteases, trypsin family, serine active site. 413999007887 Pfam match to entry PF00672 HAMP, HAMP domain,score 31.8, E-value 1.7e-06 413999007888 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 123.4, E-value 4.5e-34 413999007889 ABC transporter ATP-binding protein; Provisional; Region: PRK15064 413999007890 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999007891 Pecanex protein (C-terminus); Region: Pecanex_C; pfam05041 413999007892 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999007893 ABC transporter; Region: ABC_tran_2; pfam12848 413999007894 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999007895 Pfam match to entry PF00005 ABC_tran, ABC transporter score 44.8, E-value 2e-10 413999007896 Pfam match to entry PF00005 ABC_tran, ABC transporter score 153.0, E-value 5.6e-43 413999007897 PS00017 ATP/GTP-binding site motif A (P-loop). 413999007898 This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333 413999007899 putative deacylase active site [active] 413999007900 Pfam match to entry PF04073 YbaK, YbaK / prolyl-tRNA synthetases associated domain, score 140.2,E-value 3.9e-39 413999007901 sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912 413999007902 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 413999007903 4Fe-4S binding domain; Region: Fer4_6; pfam12837 413999007904 Pfam match to entry PF03460 NIR_SIR_ferr,Nitrite/Sulfite reductase ferredoxin-like half domain,score 27.5, E-value 3.4e-07 413999007905 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain, score 59.1, E-value 9.9e-15 413999007906 PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 413999007907 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 25.5, E-value 2.4e-05 413999007908 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 34.2, E-value 3.2e-07 413999007909 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999007910 Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835 413999007911 Response regulator receiver domain; Region: Response_reg; pfam00072 413999007912 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999007913 active site 413999007914 phosphorylation site [posttranslational modification] 413999007915 intermolecular recognition site; other site 413999007916 dimerization interface [polypeptide binding]; other site 413999007917 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 98.7, E-value 1.2e-26 413999007918 Pfam match to entry PF01584 CheW, CheW-like domain,score 87.0, E-value 4.1e-23 413999007919 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 413999007920 DEAD-like helicases superfamily; Region: DEXDc; smart00487 413999007921 ATP binding site [chemical binding]; other site 413999007922 putative Mg++ binding site [ion binding]; other site 413999007923 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999007924 nucleotide binding region [chemical binding]; other site 413999007925 ATP-binding site [chemical binding]; other site 413999007926 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 212.9, E-value 5e-61 413999007927 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 105.4, E-value 1.2e-28 413999007928 Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996 413999007929 S1 domain; Region: S1_2; pfam13509 413999007930 S1 domain; Region: S1_2; pfam13509 413999007931 Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316 413999007932 RNA binding site [nucleotide binding]; other site 413999007933 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 7.6, E-value 0.27 413999007934 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 26.9, E-value 4.8e-05 413999007935 ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776 413999007936 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 413999007937 ATP binding site [chemical binding]; other site 413999007938 Mg++ binding site [ion binding]; other site 413999007939 motif III; other site 413999007940 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999007941 nucleotide binding region [chemical binding]; other site 413999007942 ATP-binding site [chemical binding]; other site 413999007943 RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169 413999007944 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 284.2, E-value 1.7e-82 413999007945 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 413999007946 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 130.4, E-value 3.3e-36 413999007947 Pfam match to entry PF03880 DbpA, DbpA RNA binding domain, score 100.6, E-value 3.3e-27 413999007948 Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532 413999007949 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007950 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007951 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007952 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007953 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007954 Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309 413999007955 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007956 Leucine rich repeat; Region: LRR_8; pfam13855 413999007957 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007958 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007959 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999007960 Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532 413999007961 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 18.2, E-value 0.02 413999007962 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 19.9, E-value 0.0063 413999007963 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 14.6, E-value 0.25 413999007964 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 18.0, E-value 0.023 413999007965 PS00636 Nt-dnaJ domain signature. 413999007966 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 10.7, E-value 3.6 413999007967 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 12.5, E-value 1.1 413999007968 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 11.4, E-value 2.2 413999007969 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 20.2, E-value 0.0051 413999007970 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 11.3, E-value 2.5 413999007971 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 20.1, E-value 0.0053 413999007972 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 17.2, E-value 0.041 413999007973 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 13.8, E-value 0.44 413999007974 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 13.5, E-value 0.54 413999007975 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 18.2, E-value 0.021 413999007976 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 9.0, E-value 6.4 413999007977 Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193 413999007978 Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705 413999007979 1 probable transmembrane helix predicted for CBO1783 by TMHMM2.0 at aa 7-29 413999007980 Pfam match to entry PF01832 Amidase_4,Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase,score 113.4, E-value 4.6e-31 413999007981 nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055 413999007982 Ferritin-like domain; Region: Ferritin; pfam00210 413999007983 ferroxidase diiron center [ion binding]; other site 413999007984 Pfam match to entry PF00210 ferritin, Ferritin-like domain, score 159.2, E-value 7.3e-45 413999007985 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 413999007986 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999007987 active site 413999007988 phosphorylation site [posttranslational modification] 413999007989 intermolecular recognition site; other site 413999007990 dimerization interface [polypeptide binding]; other site 413999007991 Chemotaxis phosphatase CheX; Region: CheX; pfam13690 413999007992 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 107.8, E-value 2.2e-29 413999007993 Pfam match to entry PF04509 CheC, CheC-like family,score 35.4, E-value 1.4e-07 413999007994 Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406 413999007995 Chemotaxis phosphatase CheX; Region: CheX; pfam13690 413999007996 Pfam match to entry PF04509 CheC, CheC-like family,score 37.7, E-value 2.8e-08 413999007997 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314 413999007998 Nucleoside recognition; Region: Gate; pfam07670 413999007999 10 probable transmembrane helices predicted for CBO1788 by TMHMM2.0 at aa 12-34, 49-71, 92-114, 139-161,213-232, 237-259, 322-344, 368-390, 397-419 and 429-451 413999008000 Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269 413999008001 Pfam match to entry PF00269 SASP, Small,acid-soluble spore proteins, alpha/beta type, score 88.7,E-value 1.2e-23 413999008002 PS00304 Small, acid-soluble spore proteins,alpha/beta type, signature 1. 413999008003 PS00684 Small, acid-soluble spore proteins,alpha/beta type, signature 2. 413999008004 Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269 413999008005 Pfam match to entry PF00269 SASP, Small,acid-soluble spore proteins, alpha/beta type, score 80.8,E-value 3e-21 413999008006 PS00304 Small, acid-soluble spore proteins,alpha/beta type, signature 1. 413999008007 PS00684 Small, acid-soluble spore proteins,alpha/beta type, signature 2. 413999008008 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236 413999008009 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 413999008010 active site 413999008011 DNA binding site [nucleotide binding] 413999008012 Int/Topo IB signature motif; other site 413999008013 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain, score 30.3, E-value 4.8e-06 413999008014 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score 157.1, E-value 3.1e-44 413999008015 LexA repressor; Validated; Region: PRK00215 413999008016 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999008017 putative Zn2+ binding site [ion binding]; other site 413999008018 putative DNA binding site [nucleotide binding]; other site 413999008019 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 413999008020 Catalytic site [active] 413999008021 Pfam match to entry PF01726 LexA_DNA_bind, LexA DNA binding domain, score 82.5, E-value 8.9e-22 413999008022 Pfam match to entry PF00717 Peptidase_S24,Peptidase S24, score 132.4, E-value 8.4e-37 413999008023 Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100 413999008024 Aluminium resistance protein; Region: Alum_res; pfam06838 413999008025 bacterial Hfq-like; Region: Hfq; cd01716 413999008026 hexamer interface [polypeptide binding]; other site 413999008027 Sm1 motif; other site 413999008028 RNA binding site [nucleotide binding]; other site 413999008029 Sm2 motif; other site 413999008030 Pfam match to entry PF01423 LSM, LSM domain, score 66.5, E-value 5.8e-17 413999008031 tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324 413999008032 tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091 413999008033 Pfam match to entry PF01715 IPPT, IPP transferase,score 390.1, E-value 2.3e-114 413999008034 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008035 DNA mismatch repair protein MutL; Region: mutl; TIGR00585 413999008036 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999008037 ATP binding site [chemical binding]; other site 413999008038 Mg2+ binding site [ion binding]; other site 413999008039 G-X-G motif; other site 413999008040 MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782 413999008041 ATP binding site [chemical binding]; other site 413999008042 MutL C terminal dimerisation domain; Region: MutL_C; smart00853 413999008043 Pfam match to entry PF01119 DNA_mis_repair, DNA mismatch repair protein, C-terminal domain, score 119.2,E-value 7.9e-33 413999008044 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 20.6,E-value 0.0005 413999008045 PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 413999008046 PS00583 pfkB family of carbohydrate kinases signature 1. 413999008047 DNA mismatch repair protein MutS; Provisional; Region: PRK05399 413999008048 MutS domain I; Region: MutS_I; pfam01624 413999008049 MutS domain II; Region: MutS_II; pfam05188 413999008050 MutS domain III; Region: MutS_III; pfam05192 413999008051 ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284 413999008052 Walker A/P-loop; other site 413999008053 ATP binding site [chemical binding]; other site 413999008054 Q-loop/lid; other site 413999008055 ABC transporter signature motif; other site 413999008056 Walker B; other site 413999008057 D-loop; other site 413999008058 H-loop/switch region; other site 413999008059 Pfam match to entry PF00488 MutS_V, MutS domain V,score 541.9, E-value 4.5e-160 413999008060 PS00486 DNA mismatch repair proteins mutS family signature. 413999008061 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008062 Pfam match to entry PF05192 MutS_III, MutS domain III, score 267.6, E-value 1.8e-77 413999008063 Pfam match to entry PF05190 MutS_IV, MutS family domain IV, score 153.6, E-value 3.6e-43 413999008064 Pfam match to entry PF05188 MutS_II, MutS domain II, score 48.1, E-value 2e-11 413999008065 Pfam match to entry PF01624 MutS_I, MutS domain I,score 228.3, E-value 1.2e-65 413999008066 (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328 413999008067 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 413999008068 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999008069 FeS/SAM binding site; other site 413999008070 TRAM domain; Region: TRAM; pfam01938 413999008071 Pfam match to entry PF01938 TRAM, TRAM domain,score 53.3, E-value 5.6e-13 413999008072 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 133.1, E-value 5.4e-37 413999008073 PS01278 Uncharacterized protein family UPF0004 signature. 413999008074 Pfam match to entry PF00919 UPF0004,Uncharacterized protein family UPF0004, score 138.9,E-value 9.2e-39 413999008075 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436 413999008076 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999008077 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999008078 homodimer interface [polypeptide binding]; other site 413999008079 catalytic residue [active] 413999008080 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 29.7, E-value 2.7e-07 413999008081 aspartate aminotransferase; Provisional; Region: PRK07568 413999008082 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999008083 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999008084 homodimer interface [polypeptide binding]; other site 413999008085 catalytic residue [active] 413999008086 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 109.0, E-value 9.8e-30 413999008087 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 413999008088 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 413999008089 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 57.5, E-value 3e-14 413999008090 spore coat protein, CotS family; Region: spore_CotS; TIGR02906 413999008091 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; Reviewed; Region: PRK00087 413999008092 LytB protein; Region: LYTB; cl00507 413999008093 S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687 413999008094 RNA binding site [nucleotide binding]; other site 413999008095 S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465 413999008096 RNA binding site [nucleotide binding]; other site 413999008097 S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688 413999008098 RNA binding site [nucleotide binding]; other site 413999008099 S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472 413999008100 RNA binding site [nucleotide binding]; other site 413999008101 domain interface; other site 413999008102 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 97.1, E-value 3.7e-26 413999008103 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 103.9, E-value 3.3e-28 413999008104 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 5.8, E-value 0.81 413999008105 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 50.1, E-value 5.1e-12 413999008106 Pfam match to entry PF02401 LYTB, LytB protein,score 323.9, E-value 2e-94 413999008107 cytidylate kinase; Provisional; Region: cmk; PRK00023 413999008108 Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020 413999008109 CMP-binding site; other site 413999008110 The sites determining sugar specificity; other site 413999008111 Pfam match to entry PF02224 Cytidylate_kin,Cytidylate kinase, score 219.2, E-value 6.2e-63 413999008112 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008113 Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185 413999008114 homotrimer interaction site [polypeptide binding]; other site 413999008115 active site 413999008116 flavoprotein, HI0933 family; Region: TIGR00275 413999008117 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999008118 Pfam match to entry PF03486 HI0933_like,HI0933-like protein, score 484.7, E-value 7.9e-143 413999008119 Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334 413999008120 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812 413999008121 NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076 413999008122 NAD(P) binding site [chemical binding]; other site 413999008123 Pfam match to entry PF00208 GLFV_dehydrog,Glutamate/Leucine/Phenylalanine/Valine dehydrogenase,score 346.2, E-value 3.8e-101 413999008124 Pfam match to entry PF02812 GLFV_dehydrog_N,Glu/Leu/Phe/Val dehydrogenase, dimerisation domain, score 290.3, E-value 2.6e-84 413999008125 PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 413999008126 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999008127 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999008128 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999008129 putative active site [active] 413999008130 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family, score 34.4, E-value 2.7e-07 413999008131 Predicted helix-turn-helix motif with score 1215.000, SD 3.33 at aa 40-61, sequence MTAAKLGTSVGVSESTVVRFAN 413999008132 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 413999008133 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999008134 RNA binding surface [nucleotide binding]; other site 413999008135 Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870 413999008136 active site 413999008137 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase, score 81.3, E-value 2.1e-21 413999008138 PS01149 Rsu family of pseudouridine synthase signature. 413999008139 Pfam match to entry PF01479 S4, S4 domain, score 37.0, E-value 4.6e-08 413999008140 Domain of unknown function (DUF2088); Region: DUF2088; pfam09861 413999008141 L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681 413999008142 Pfam match to entry PF06354 DUF1063, Protein of unknown function (DUF1063), score 401.3, E-value 9.8e-118 413999008143 Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215 413999008144 EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438 413999008145 DXD motif; other site 413999008146 6 probable transmembrane helices predicted for CBO1816 by TMHMM2.0 at aa 10-32, 300-322, 342-361,368-387, 397-414 and 423-445 413999008147 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 34.6, E-value 2.4e-07 413999008148 Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402 413999008149 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999008150 dimerization interface [polypeptide binding]; other site 413999008151 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999008152 dimer interface [polypeptide binding]; other site 413999008153 Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015 413999008154 putative CheW interface [polypeptide binding]; other site 413999008155 2 probable transmembrane helices predicted for CBO1818 by TMHMM2.0 at aa 15-34 and 293-315 413999008156 Pfam match to entry PF00672 HAMP, HAMP domain,score 69.7, E-value 6.4e-18 413999008157 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 201.9, E-value 1.1e-57 413999008158 Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785 413999008159 Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788 413999008160 6 probable transmembrane helices predicted for CBO1819 by TMHMM2.0 at aa 15-48, 61-83, 93-112, 133-155,170-192 and 204-226 413999008161 Pfam match to entry PF02683 DsbD, Cytochrome C biogenesis protein transmembrane region, score 101.8,E-value 1.4e-27 413999008162 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 413999008163 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 413999008164 catalytic residues [active] 413999008165 Pfam match to entry PF00085 thiored, Thioredoxin,score 44.5, E-value 2.5e-10 413999008166 PS00194 Thioredoxin family active site. 413999008167 1 probable transmembrane helix predicted for CBO1820 by TMHMM2.0 at aa 21-40 413999008168 Predicted amidohydrolase [General function prediction only]; Region: COG0388 413999008169 Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572 413999008170 putative active site [active] 413999008171 catalytic triad [active] 413999008172 dimer interface [polypeptide binding]; other site 413999008173 Pfam match to entry PF00795 CN_hydrolase,Carbon-nitrogen hydrolase, score 292.5, E-value 5.4e-85 413999008174 PS01227 Uncharacterized protein family UPF0012 signature. 413999008175 3 probable transmembrane helices predicted for CBO1822 by TMHMM2.0 at aa 5-27, 48-65 and 69-86 413999008176 1 probable transmembrane helix predicted for CBO1823 by TMHMM2.0 at aa 21-39 413999008177 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 413999008178 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 413999008179 TrkA-C domain; Region: TrkA_C; pfam02080 413999008180 11 probable transmembrane helices predicted for CBO1824 by TMHMM2.0 at aa 4-26, 33-52, 57-77, 90-112,125-143, 156-175, 188-205, 277-299, 304-326, 335-357 and 367-385 413999008181 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 56.8, E-value 5e-14 413999008182 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599 413999008183 Pfam match to entry PF02627 CMD,Carboxymuconolactone decarboxylase, score 91.7,E-value 1.6e-24 413999008184 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 413999008185 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999008186 Coenzyme A binding pocket [chemical binding]; other site 413999008187 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 67.8, E-value 2.4e-17 413999008188 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 413999008189 active site residue [active] 413999008190 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999008191 Putative heavy-metal-binding; Region: YbjQ_1; cl00426 413999008192 Pfam match to entry PF01906 DUF74, Domain of unknown function DUF74, score 159.0, E-value 8.6e-45 413999008193 Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980 413999008194 dimer interface [polypeptide binding]; other site 413999008195 [2Fe-2S] cluster binding site [ion binding]; other site 413999008196 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999008197 [FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512 413999008198 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999008199 Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906 413999008200 Putative Fe-S cluster; Region: FeS; cl17515 413999008201 PAS domain; Region: PAS_9; pfam13426 413999008202 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999008203 putative active site [active] 413999008204 heme pocket [chemical binding]; other site 413999008205 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 20.7, E-value 0.00014 413999008206 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008207 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 31.0, E-value 2.8e-06 413999008208 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008209 Pfam match to entry PF02906 Fe_hyd_lg_C, Iron only hydrogenase large subunit, C-terminal domain, score -76.5,E-value 7.5e-12 413999008210 Pfam match to entry PF04060 FeS, Fe-S cluster, score 21.8, E-value 0.00034 413999008211 Pfam match to entry PF00989 PAS, PAS domain, score 18.5, E-value 0.00011 413999008212 Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228 413999008213 [FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512 413999008214 4Fe-4S binding domain; Region: Fer4; pfam00037 413999008215 Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906 413999008216 Putative Fe-S cluster; Region: FeS; cl17515 413999008217 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999008218 putative active site [active] 413999008219 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 20.9, E-value 0.00013 413999008220 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008221 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 32.4, E-value 1.1e-06 413999008222 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008223 Pfam match to entry PF02906 Fe_hyd_lg_C, Iron only hydrogenase large subunit, C-terminal domain, score -76.2,E-value 7.2e-12 413999008224 Pfam match to entry PF04060 FeS, Fe-S cluster, score 22.3, E-value 0.0003 413999008225 HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis. HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197 413999008226 dimerization interface [polypeptide binding]; other site 413999008227 hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124 413999008228 ATP binding site [chemical binding]; other site 413999008229 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain, score 71.1, E-value 2.4e-18 413999008230 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain, score 175.1, E-value 1.2e-49 413999008231 Hydrogenase formation hypA family; Region: HypD; pfam01924 413999008232 hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075 413999008233 Pfam match to entry PF01924 HypD, Hydrogenase formation hypA family, score 392.6, E-value 4e-115 413999008234 Acylphosphatase; Region: Acylphosphatase; pfam00708 413999008235 Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068 413999008236 HypF finger; Region: zf-HYPF; pfam07503 413999008237 HypF finger; Region: zf-HYPF; pfam07503 413999008238 Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300 413999008239 Pfam match to entry PF01300 Sua5_yciO_yrdC, yrdC domain, score 162.0, E-value 1.1e-45 413999008240 Pfam match to entry PF00708 Acylphosphatase,Acylphosphatase, score 20.7, E-value 6.4e-07 413999008241 PS00150 Acylphosphatase signature 1. 413999008242 Cytochrome b5-like Heme/Steroid binding domain; Region: Cyt-b5; cl02041 413999008243 Pfam match to entry PF00173 heme_1, Heme/Steroid binding domain, score 49.1, E-value 1e-11 413999008244 Hydrogenase specific C-terminal endopeptidases, also called Hydrogen Maturation Proteases (H2MP). These enzymes belong to the peptidase family M52. Maturation of [FeNi] hydrogenases includes formation of the nickel metallocenter, proteolytic processing...; Region: H2MP; cd00518 413999008245 nickel binding site [ion binding]; other site 413999008246 Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374 413999008247 Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374 413999008248 Pfam match to entry PF00374 NiFeSe_Hases,Nickel-dependent hydrogenase, score 305.2, E-value 8.1e-89 413999008249 PS00508 Nickel-dependent hydrogenases large subunit signature 2. 413999008250 PS00507 Nickel-dependent hydrogenases large subunit signature 1. 413999008251 Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740 413999008252 NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058 413999008253 PS00559 Eukaryotic molybdopterin oxidoreductases signature. 413999008254 Pfam match to entry PF01058 oxidored_q6, NADH ubiquinone oxidoreductase, 20 Kd subunit, score -5.3,E-value 0.00012 413999008255 TraX protein; Region: TraX; pfam05857 413999008256 Pfam match to entry PF05857 TraX, TraX protein,score -11.2, E-value 0.00074 413999008257 6 probable transmembrane helices predicted for CBO1842 by TMHMM2.0 at aa 31-53, 60-82, 92-109, 155-177,182-201 and 214-232 413999008258 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105 413999008259 2 probable transmembrane helices predicted for CBO1843 by TMHMM2.0 at aa 35-52 and 62-84 413999008260 1 probable transmembrane helix predicted for CBO1844 by TMHMM2.0 at aa 5-27 413999008261 1 probable transmembrane helix predicted for CBO1845 by TMHMM2.0 at aa 5-27 413999008262 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 413999008263 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999008264 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999008265 Walker A/P-loop; other site 413999008266 ATP binding site [chemical binding]; other site 413999008267 Q-loop/lid; other site 413999008268 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999008269 ABC transporter signature motif; other site 413999008270 ABC transporter; Region: ABC_tran_2; pfam12848 413999008271 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999008272 Pfam match to entry PF00005 ABC_tran, ABC transporter score 91.1, E-value 2.4e-24 413999008273 PS00211 ABC transporters family signature. 413999008274 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008275 Pfam match to entry PF00005 ABC_tran, ABC transporter score 141.6, E-value 1.4e-39 413999008276 PS00211 ABC transporters family signature. 413999008277 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008278 bidirectional hydrogenase complex protein HoxU; Validated; Region: PRK07569 413999008279 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 413999008280 catalytic loop [active] 413999008281 iron binding site [ion binding]; other site 413999008282 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588 413999008283 [FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512 413999008284 4Fe-4S binding domain; Region: Fer4; pfam00037 413999008285 Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906 413999008286 Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256 413999008287 Pfam match to entry PF02256 Fe_hyd_SSU, Iron hydrogenase small subunit, score 85.1, E-value 1.5e-22 413999008288 Pfam match to entry PF02906 Fe_hyd_lg_C, Iron only hydrogenase large subunit, C-terminal domain, score 660.9,E-value 7.1e-196 413999008289 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 33.5, E-value 5e-07 413999008290 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008291 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 8.5, E-value 0.012 413999008292 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain, score 30.9, E-value 3e-06 413999008293 Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980 413999008294 dimer interface [polypeptide binding]; other site 413999008295 [2Fe-2S] cluster binding site [ion binding]; other site 413999008296 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894 413999008297 SLBB domain; Region: SLBB; pfam10531 413999008298 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589 413999008299 4Fe-4S dicluster domain; Region: Fer4_9; pfam13187 413999008300 4Fe-4S binding domain; Region: Fer4; pfam00037 413999008301 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 40.4, E-value 4.3e-09 413999008302 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008303 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 20.7, E-value 0.00014 413999008304 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999008305 PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 413999008306 Pfam match to entry PF01512 Complex1_51K,Respiratory-chain NADH dehydrogenase 51 Kd subunit, score 550.5, E-value 1.2e-162 413999008307 Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257 413999008308 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064 413999008309 putative dimer interface [polypeptide binding]; other site 413999008310 [2Fe-2S] cluster binding site [ion binding]; other site 413999008311 Pfam match to entry PF01257 complex1_24kD,Respiratory-chain NADH dehydrogenase 24 Kd subunit, score 119.1, E-value 8.8e-33 413999008312 Predicted helix-turn-helix motif with score 1131.000, SD 3.04 at aa 45-66, sequence EVQEFVAKKLDISVSKVYGVIT 413999008313 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 413999008314 Pfam match to entry PF00999 Na_H_Exchanger,Sodium/hydrogen exchanger family, score 167.0, E-value 3.4e-47 413999008315 9 probable transmembrane helices predicted for CBO1850 by TMHMM2.0 at aa 24-46, 115-137, 150-172,187-209, 220-237, 274-296, 298-320, 335-357 and 362-384 413999008316 ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747 413999008317 Pfam match to entry PF03747 ADP-ribosyl_GH,ADP-ribosylglycohydrolase, score 147.0, E-value 3.5e-41 413999008318 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 413999008319 Domain of unknown function DUF20; Region: UPF0118; pfam01594 413999008320 8 probable transmembrane helices predicted for CBO1852 by TMHMM2.0 at aa 7-29, 39-59, 72-94, 164-186,233-255, 265-287, 289-308 and 323-345 413999008321 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20, score 231.4, E-value 1.4e-66 413999008322 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 413999008323 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 413999008324 Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936 413999008325 Pfam match to entry PF00768 Peptidase_S11,D-alanyl-D-alanine carboxypeptidase, score 253.5, E-value 3e-73 413999008326 Protein of unknown function (DUF2953); Region: DUF2953; pfam11167 413999008327 3 probable transmembrane helices predicted for CBO1854 by TMHMM2.0 at aa 2-24, 94-116 and 137-159 413999008328 sporulation protein YtfJ; Region: spore_ytfJ; TIGR02874 413999008329 segregation and condensation protein B; Reviewed; Region: scpB; PRK00135 413999008330 Pfam match to entry PF04079 DUF387, transcriptional regulators (Ypuh-like), score 224.7,E-value 1.4e-64 413999008331 Predicted helix-turn-helix motif with score 1262.000, SD 3.49 at aa 35-56, sequence INIKDLATILNCKQDKVSSLLN 413999008332 segregation and condensation protein A; Reviewed; Region: scpA; PRK00104 413999008333 Pfam match to entry PF02616 DUF173, Uncharacterised ACR, COG1354, score 127.5, E-value 2.5e-35 413999008334 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 413999008335 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 413999008336 Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936 413999008337 Pfam match to entry PF00768 Peptidase_S11,D-alanyl-D-alanine carboxypeptidase, score 337.7, E-value 1.4e-98 413999008338 EcsC protein family; Region: EcsC; pfam12787 413999008339 1 probable transmembrane helix predicted for CBO1860 by TMHMM2.0 at aa 97-119 413999008340 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 413999008341 putative catalytic site [active] 413999008342 putative metal binding site [ion binding]; other site 413999008343 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 413999008344 putative catalytic site [active] 413999008345 putative phosphate binding site [ion binding]; other site 413999008346 putative phosphate binding site [ion binding]; other site 413999008347 putative metal binding site [ion binding]; other site 413999008348 Pfam match to entry PF03372 Exo_endo_phos,Endonuclease/Exonuclease/phosphatase, score 59.5,E-value 7.5e-15 413999008349 pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078 413999008350 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 413999008351 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 413999008352 Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941 413999008353 Pfam match to entry PF00591 Glycos_transf_3,Glycosyl transferase, a/b domain, score 151.2,E-value 1.9e-42 413999008354 PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 413999008355 Pfam match to entry PF02885 Glycos_trans_3N,Glycosyl transferase, helical bundle domain, score 60.2, E-value 4.6e-15 413999008356 purine nucleoside phosphorylase; Provisional; Region: PRK08202 413999008357 Pfam match to entry PF00896 Mtap_PNP, Phosphorylase 2, score 370.4, E-value 2e-108 413999008358 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 413999008359 tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225 413999008360 Int/Topo IB signature motif; other site 413999008361 active site 413999008362 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score 132.5, E-value 8.2e-37 413999008363 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain, score 67.5, E-value 2.9e-17 413999008364 stage II sporulation protein M; Region: spo_II_M; TIGR02831 413999008365 5 probable transmembrane helices predicted for CBO1866 by TMHMM2.0 at aa 16-38, 79-101, 108-130, 135-157 and 170-192 413999008366 nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052 413999008367 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 413999008368 dimer interface [polypeptide binding]; other site 413999008369 ADP-ribose binding site [chemical binding]; other site 413999008370 active site 413999008371 nudix motif; other site 413999008372 metal binding site [ion binding]; metal-binding site 413999008373 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 79.1, E-value 9.8e-21 413999008374 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008375 PS00893 mutT domain signature. 413999008376 inner membrane transporter YjeM; Provisional; Region: PRK15238 413999008377 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score -70.4, E-value 2.3e-05 413999008378 12 probable transmembrane helices predicted for CBO1868 by TMHMM2.0 at aa 13-35, 45-67, 88-111, 126-148,165-187, 215-237, 250-272, 318-340, 368-389, 399-421,441-460 and 470-492 413999008379 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 413999008380 NlpC/P60 family; Region: NLPC_P60; pfam00877 413999008381 PS00141 Eukaryotic and viral aspartyl proteases active site. 413999008382 Pfam match to entry PF00877 NLPC_P60, NlpC/P60 family, score 154.6, E-value 1.8e-43 413999008383 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 413999008384 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score -12.6, E-value 0.00037 413999008385 sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875 413999008386 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999008387 active site 413999008388 phosphorylation site [posttranslational modification] 413999008389 intermolecular recognition site; other site 413999008390 dimerization interface [polypeptide binding]; other site 413999008391 Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769 413999008392 Predicted helix-turn-helix motif with score 1004.000, SD 2.61 at aa 213-234, sequence ELYPSIAKKYNTTASRVERAIR 413999008393 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 105.9, E-value 8.4e-29 413999008394 stage IV sporulation protein B; Region: spore_IV_B; TIGR02860 413999008395 SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580 413999008396 Pfam match to entry PF05580 Peptidase_S55, SpoIVB peptidase S55, score 471.1, E-value 9.2e-139 413999008397 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF), score 21.7, E-value 0.0018 413999008398 Homoserine O-succinyltransferase; Region: HTS; pfam04204 413999008399 Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131 413999008400 conserved cys residue [active] 413999008401 Pfam match to entry PF04204 HTS, Homoserine O-succinyltransferase, score 494.0, E-value 1.2e-145 413999008402 Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460 413999008403 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 413999008404 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 413999008405 Pfam match to entry PF00742 Homoserine_dh,Homoserine dehydrogenase, score 168.4, E-value 1.3e-47 413999008406 Pfam match to entry PF03447 NAD_binding_3,Homoserine dehydrogenase, NAD binding domain, score 114.5,E-value 2.1e-31 413999008407 O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873 413999008408 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 413999008409 homodimer interface [polypeptide binding]; other site 413999008410 substrate-cofactor binding pocket; other site 413999008411 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999008412 catalytic residue [active] 413999008413 Pfam match to entry PF01053 Cys_Met_Meta_PP,Cys/Met metabolism PLP-dependent enzyme, score 596.9,E-value 1.3e-176 413999008414 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497 413999008415 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 413999008416 Walker A/P-loop; other site 413999008417 ATP binding site [chemical binding]; other site 413999008418 Q-loop/lid; other site 413999008419 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 413999008420 ABC transporter signature motif; other site 413999008421 Walker B; other site 413999008422 D-loop; other site 413999008423 H-loop/switch region; other site 413999008424 Predicted helix-turn-helix motif with score 1018.000, SD 2.65 at aa 489-510, sequence FCITHLSQIACMSDNHYYIHKE 413999008425 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain, score 20.0, E-value 1.4e-05 413999008426 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008427 arginine repressor; Provisional; Region: argR; PRK00441 413999008428 Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316 413999008429 Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863 413999008430 Pfam match to entry PF02863 Arg_repressor_C,Arginine repressor, C-terminal domain, score 56.5, E-value 5.9e-14 413999008431 Pfam match to entry PF01316 Arg_repressor, Arginine repressor, DNA binding domain, score 95.9, E-value 8.6e-26 413999008432 NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061 413999008433 ATP-NAD kinase; Region: NAD_kinase; pfam01513 413999008434 Pfam match to entry PF01513 NAD_kinase, ATP-NAD kinase, score 244.0, E-value 2.2e-70 413999008435 Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189 413999008436 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999008437 RNA binding surface [nucleotide binding]; other site 413999008438 FtsJ-like methyltransferase; Region: FtsJ; pfam01728 413999008439 Pfam match to entry PF01728 FtsJ, FtsJ-like methyltransferase, score 3.2, E-value 3.6e-07 413999008440 Pfam match to entry PF01479 S4, S4 domain, score 38.6, E-value 1.5e-08 413999008441 1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444 413999008442 Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007 413999008443 TPP-binding site; other site 413999008444 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 413999008445 PYR/PP interface [polypeptide binding]; other site 413999008446 dimer interface [polypeptide binding]; other site 413999008447 TPP binding site [chemical binding]; other site 413999008448 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 413999008449 Pfam match to entry PF02780 transketolase_C,Transketolase, C-terminal domain, score 114.0, E-value 3e-31 413999008450 Pfam match to entry PF02779 transket_pyr,Transketolase, pyridine binding domain, score 189.8,E-value 4.7e-54 413999008451 PS00801 Transketolase signature 1. 413999008452 2 probable transmembrane helices predicted for CBO1882 by TMHMM2.0 at aa 20-42 and 52-74 413999008453 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 413999008454 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 413999008455 substrate binding pocket [chemical binding]; other site 413999008456 chain length determination region; other site 413999008457 substrate-Mg2+ binding site; other site 413999008458 catalytic residues [active] 413999008459 aspartate-rich region 1; other site 413999008460 active site lid residues [active] 413999008461 aspartate-rich region 2; other site 413999008462 Pfam match to entry PF00348 polyprenyl_synt,Polyprenyl synthetase, score 289.7, E-value 3.8e-84 413999008463 PS00444 Polyprenyl synthetases signature 2. 413999008464 PS00723 Polyprenyl synthetases signature 1. 413999008465 exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977 413999008466 Pfam match to entry PF02609 Exonuc_VII_S,Exonuclease VII small subunit, score 68.3, E-value 1.7e-17 413999008467 exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286 413999008468 ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489 413999008469 generic binding surface I; other site 413999008470 generic binding surface II; other site 413999008471 Pfam match to entry PF02601 Exonuc_VII_L,Exonuclease VII, large subunit, score 139.6, E-value 5.7e-39 413999008472 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 44.1, E-value 3.3e-10 413999008473 transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202 413999008474 Pfam match to entry PF01029 NusB, NusB family,score 117.2, E-value 3.2e-32 413999008475 Asp23 family; Region: Asp23; pfam03780 413999008476 Pfam match to entry PF03780 DUF322, Protein of unknown function (DUF322), score 137.8, E-value 2e-38 413999008477 SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685 413999008478 1 probable transmembrane helix predicted for CBO1888 by TMHMM2.0 at aa 7-24 413999008479 stage III sporulation protein AG; Region: spore_III_AG; TIGR02830 413999008480 1 probable transmembrane helix predicted for CBO1889 by TMHMM2.0 at aa 21-40 413999008481 stage III sporulation protein AF; Region: spore_III_AF; TIGR02896 413999008482 2 probable transmembrane helices predicted for CBO1890 by TMHMM2.0 at aa 7-27 and 37-56 413999008483 Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; pfam09546 413999008484 8 probable transmembrane helices predicted for CBO1891 by TMHMM2.0 at aa 5-27, 93-115, 128-147, 162-184,196-218, 238-260, 307-329 and 356-378 413999008485 PS00043 Bacterial regulatory proteins, gntR family signature. 413999008486 stage III sporulation protein AD; Region: spore_III_AD; TIGR02849 413999008487 4 probable transmembrane helices predicted for CBO1892 by TMHMM2.0 at aa 3-20, 30-52, 65-87 and 102-124 413999008488 stage III sporulation protein AC; Region: spore_III_AC; TIGR02848 413999008489 2 probable transmembrane helices predicted for CBO1893 by TMHMM2.0 at aa 12-30 and 40-62 413999008490 stage III sporulation protein SpoAB; Provisional; Region: PRK08307 413999008491 2 probable transmembrane helices predicted for CBO1894 by TMHMM2.0 at aa 4-21 and 154-171 413999008492 stage III sporulation protein AA; Region: spore_III_AA; TIGR02858 413999008493 PS00294 Prenyl group binding site (CAAX box). 413999008494 elongation factor P; Validated; Region: PRK00529 413999008495 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 413999008496 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 413999008497 RNA binding site [nucleotide binding]; other site 413999008498 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 413999008499 RNA binding site [nucleotide binding]; other site 413999008500 Pfam match to entry PF01132 EFP, Elongation factor P (EF-P), score 343.6, E-value 2.3e-100 413999008501 PS01275 Elongation factor P signature. 413999008502 Dehydroquinase class II; Region: DHquinase_II; pfam01220 413999008503 Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466 413999008504 trimer interface [polypeptide binding]; other site 413999008505 active site 413999008506 dimer interface [polypeptide binding]; other site 413999008507 Pfam match to entry PF01220 DHquinase_II,Dehydroquinase class II, score 256.6, E-value 3.4e-74 413999008508 1 probable transmembrane helix predicted for CBO1898 by TMHMM2.0 at aa 122-144 413999008509 PS01029 Dehydroquinase class II signature. 413999008510 Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703 413999008511 Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464 413999008512 ADP binding site [chemical binding]; other site 413999008513 magnesium binding site [ion binding]; other site 413999008514 putative shikimate binding site; other site 413999008515 Pfam match to entry PF01202 SKI, Shikimate kinase,score 144.9, E-value 1.5e-40 413999008516 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008517 Type IV pilus 413999008518 1 probable transmembrane helix predicted for CBO1901 by TMHMM2.0 at aa 23-42 413999008519 Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165 413999008520 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830 413999008521 1 probable transmembrane helix predicted for CBO1905 by TMHMM2.0 at aa 4-21 413999008522 1 probable transmembrane helix predicted for CBO1906 by TMHMM2.0 at aa 9-31 413999008523 Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165 413999008524 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544 413999008525 1 probable transmembrane helix predicted for CBO1907 by TMHMM2.0 at aa 13-35 413999008526 PS00409 Prokaryotic N-terminal methylation site. 413999008527 Pfam match to entry PF00114 pilin, Pilin (bacterial filament), score 18.6, E-value 1.1e-05 413999008528 Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459 413999008529 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 413999008530 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 413999008531 Pfam match to entry PF00482 GSPII_F, Bacterial type II secretion system protein F domain, score 104.2, E-value 2.7e-28 413999008532 3 probable transmembrane helices predicted for CBO1908 by TMHMM2.0 at aa 163-185, 212-234 and 370-392 413999008533 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804 413999008534 Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157 413999008535 PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129 413999008536 Walker A motif; other site 413999008537 ATP binding site [chemical binding]; other site 413999008538 Walker B motif; other site 413999008539 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein, score 357.3, E-value 1.8e-104 413999008540 PS00662 Bacterial type II secretion system protein E signature. 413999008541 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008542 Pfam match to entry PF05157 GSPII_E_N, GSPII_E N-terminal domain, score 28.2, E-value 2.1e-05 413999008543 1 probable transmembrane helix predicted for CBO1910 by TMHMM2.0 at aa 20-39 413999008544 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999008545 1 probable transmembrane helix predicted for CBO1911 by TMHMM2.0 at aa 5-22 413999008546 diaminopimelate epimerase; Provisional; Region: dapF; PRK00450 413999008547 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 413999008548 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 413999008549 Pfam match to entry PF01678 DAP_epimerase,Diaminopimelate epimerase, score 78.9, E-value 1.1e-20 413999008550 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999008551 Pfam match to entry PF01678 DAP_epimerase,Diaminopimelate epimerase, score 146.6, E-value 4.7e-41 413999008552 PS01326 Diaminopimelate epimerase signature. 413999008553 Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833 413999008554 Domain of unknown function (DUF814); Region: DUF814; pfam05670 413999008555 Pfam match to entry PF05833 FbpA,Fibronectin-binding protein A N-terminus (FbpA), score 617.3, E-value 9.2e-183 413999008556 Pfam match to entry PF05670 DUF814, Domain of unknown function (DUF814), score 159.6, E-value 5.7e-45 413999008557 tRNA pseudouridine synthase A; Reviewed; Region: PRK12434 413999008558 Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA; Region: PseudoU_synth_EcTruA; cd02570 413999008559 dimerization interface 3.5A [polypeptide binding]; other site 413999008560 active site 413999008561 Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase, score 73.4, E-value 4.8e-19 413999008562 Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase, score 77.9, E-value 2.2e-20 413999008563 FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275 413999008564 nucleotide binding site/active site [active] 413999008565 HIT family signature motif; other site 413999008566 catalytic residue [active] 413999008567 Pfam match to entry PF01230 HIT, HIT domain, score 77.4, E-value 3e-20 413999008568 PS00892 HIT family signature. 413999008569 DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450 413999008570 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999008571 catalytic residue [active] 413999008572 Pfam match to entry PF00282 pyridoxal_deC,Pyridoxal-dependent decarboxylase domain, score 261.3, E-value 1.4e-75 413999008573 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 413999008574 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 413999008575 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999008576 dimerization interface [polypeptide binding]; other site 413999008577 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999008578 dimer interface [polypeptide binding]; other site 413999008579 putative CheW interface [polypeptide binding]; other site 413999008580 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 62.3, E-value 1.1e-15 413999008581 Pfam match to entry PF00672 HAMP, HAMP domain,score 57.4, E-value 3.2e-14 413999008582 2 probable transmembrane helices predicted for CBO1919 by TMHMM2.0 at aa 10-28 and 189-208 413999008583 clostripain; Region: clostrip; TIGR02806 413999008584 Pfam match to entry PF03415 Peptidase_C11,Clostripain family, score 724.2, E-value 5.9e-215 413999008585 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999008586 M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393 413999008587 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999008588 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999008589 active site 413999008590 phosphorylation site [posttranslational modification] 413999008591 intermolecular recognition site; other site 413999008592 dimerization interface [polypeptide binding]; other site 413999008593 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999008594 DNA binding site [nucleotide binding] 413999008595 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999008596 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999008597 dimer interface [polypeptide binding]; other site 413999008598 phosphorylation site [posttranslational modification] 413999008599 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999008600 ATP binding site [chemical binding]; other site 413999008601 Mg2+ binding site [ion binding]; other site 413999008602 G-X-G motif; other site 413999008603 4 probable transmembrane helices predicted for CBO1922 by TMHMM2.0 at aa 15-37, 255-277, 311-330 and 337-359 413999008604 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 77.0, E-value 4.1e-20 413999008605 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 57.9,E-value 2.3e-14 413999008606 methionine sulfoxide reductase A; Provisional; Region: PRK14054 413999008607 Pfam match to entry PF01625 PMSR, Peptide methionine sulfoxide reductase, score 326.5, E-value 3.3e-95 413999008608 Response regulator receiver domain; Region: Response_reg; pfam00072 413999008609 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999008610 active site 413999008611 phosphorylation site [posttranslational modification] 413999008612 intermolecular recognition site; other site 413999008613 dimerization interface [polypeptide binding]; other site 413999008614 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 413999008615 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999008616 active site 413999008617 phosphorylation site [posttranslational modification] 413999008618 intermolecular recognition site; other site 413999008619 dimerization interface [polypeptide binding]; other site 413999008620 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 36.0, E-value 8.9e-08 413999008621 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 46.4, E-value 6.8e-11 413999008622 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999008623 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999008624 dimerization interface [polypeptide binding]; other site 413999008625 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999008626 dimer interface [polypeptide binding]; other site 413999008627 phosphorylation site [posttranslational modification] 413999008628 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999008629 ATP binding site [chemical binding]; other site 413999008630 Mg2+ binding site [ion binding]; other site 413999008631 G-X-G motif; other site 413999008632 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 122.5, E-value 8.2e-34 413999008633 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 64.5, E-value 2.4e-16 413999008634 Pfam match to entry PF00672 HAMP, HAMP domain,score 36.5, E-value 6.2e-08 413999008635 2 probable transmembrane helices predicted for CBO1925 by TMHMM2.0 at aa 20-42 and 177-199 413999008636 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999008637 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999008638 active site 413999008639 phosphorylation site [posttranslational modification] 413999008640 intermolecular recognition site; other site 413999008641 dimerization interface [polypeptide binding]; other site 413999008642 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999008643 DNA binding site [nucleotide binding] 413999008644 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 80.3, E-value 4.3e-21 413999008645 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 140.1, E-value 4.2e-39 413999008646 6 probable transmembrane helices predicted for CBO1927 by TMHMM2.0 at aa 20-39, 59-81, 115-137, 164-186,193-215 and 230-252 413999008647 ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866 413999008648 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999008649 5 probable transmembrane helices predicted for CBO1928 by TMHMM2.0 at aa 38-60, 81-103, 139-161, 168-190 and 234-256 413999008650 gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740 413999008651 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999008652 Walker A/P-loop; other site 413999008653 ATP binding site [chemical binding]; other site 413999008654 Q-loop/lid; other site 413999008655 ABC transporter signature motif; other site 413999008656 Walker B; other site 413999008657 D-loop; other site 413999008658 H-loop/switch region; other site 413999008659 Pfam match to entry PF00005 ABC_tran, ABC transporter score 187.8, E-value 1.8e-53 413999008660 PS00211 ABC transporters family signature. 413999008661 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008662 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999008663 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999008664 ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254 413999008665 Walker A/P-loop; other site 413999008666 ATP binding site [chemical binding]; other site 413999008667 Q-loop/lid; other site 413999008668 ABC transporter signature motif; other site 413999008669 Walker B; other site 413999008670 D-loop; other site 413999008671 H-loop/switch region; other site 413999008672 Pfam match to entry PF00005 ABC_tran, ABC transporter score 195.1, E-value 1.2e-55 413999008673 PS00211 ABC transporters family signature. 413999008674 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008675 Predicted helix-turn-helix motif with score 1223.000, SD 3.35 at aa 330-351, sequence QPISQVAQIANVLQSTAASAER 413999008676 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 194.5, E-value 1.7e-55 413999008677 5 probable transmembrane helices predicted for CBO1930 by TMHMM2.0 at aa 42-64, 101-123, 180-197, 201-220 and 287-309 413999008678 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999008679 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999008680 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 413999008681 Walker A/P-loop; other site 413999008682 ATP binding site [chemical binding]; other site 413999008683 Q-loop/lid; other site 413999008684 ABC transporter signature motif; other site 413999008685 Walker B; other site 413999008686 D-loop; other site 413999008687 H-loop/switch region; other site 413999008688 Pfam match to entry PF00005 ABC_tran, ABC transporter score 188.9, E-value 8.4e-54 413999008689 PS00211 ABC transporters family signature. 413999008690 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008691 6 probable transmembrane helices predicted for CBO1931 by TMHMM2.0 at aa 7-26, 258-280, 326-344, 354-376,435-457 and 472-494 413999008692 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 81.0, E-value 2.5e-21 413999008693 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999008694 MarR family; Region: MarR; pfam01047 413999008695 Pfam match to entry PF01047 MarR, MarR family,score 72.7, E-value 7.9e-19 413999008696 hypothetical protein; Provisional; Region: PRK08328 413999008697 ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757 413999008698 ATP binding site [chemical binding]; other site 413999008699 substrate interface [chemical binding]; other site 413999008700 Pfam match to entry PF05237 MoeZ_MoeB, MoeZ/MoeB domain, score 21.2, E-value 3.3e-06 413999008701 Pfam match to entry PF00899 ThiF, ThiF family,score 170.2, E-value 3.7e-48 413999008702 Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754 413999008703 MoaE interaction surface [polypeptide binding]; other site 413999008704 MoeB interaction surface [polypeptide binding]; other site 413999008705 thiocarboxylated glycine; other site 413999008706 Pfam match to entry PF02597 ThiS, ThiS family,score 22.4, E-value 8.9e-07 413999008707 Aldehyde:ferredoxin oxidoreductase [Energy production and conversion]; Region: COG2414 413999008708 Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730 413999008709 Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314 413999008710 Pfam match to entry PF01314 AFOR_C, Aldehyde ferredoxin oxidoreductase, domains 2 & 3, score 485.5,E-value 4.3e-143 413999008711 Pfam match to entry PF02730 AFOR_N, Aldehyde ferredoxin oxidoreductase, N-terminal domain, score 365.1,E-value 7.4e-107 413999008712 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008713 1 probable transmembrane helix predicted for CBO1936 by TMHMM2.0 at aa 18-40 413999008714 DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388 413999008715 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999008716 putative active site [active] 413999008717 heme pocket [chemical binding]; other site 413999008718 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999008719 Walker A motif; other site 413999008720 ATP binding site [chemical binding]; other site 413999008721 Walker B motif; other site 413999008722 arginine finger; other site 413999008723 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999008724 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 65.7, E-value 1.1e-16 413999008725 Predicted helix-turn-helix motif with score 1631.000, SD 4.74 at aa 605-626, sequence GNVSSAARALGIGRNTLYRKIE 413999008726 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999008727 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 431.0, E-value 1.1e-126 413999008728 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999008729 MOSC domain; Region: MOSC; pfam03473 413999008730 Pfam match to entry PF03473 MOSC, MOSC domain,score 88.4, E-value 1.5e-23 413999008731 MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420 413999008732 trimer interface [polypeptide binding]; other site 413999008733 dimer interface [polypeptide binding]; other site 413999008734 putative active site [active] 413999008735 PS00014 Endoplasmic reticulum targeting sequence. 413999008736 Pfam match to entry PF01967 MoaC, MoaC family,score 294.3, E-value 1.5e-85 413999008737 molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666 413999008738 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999008739 FeS/SAM binding site; other site 413999008740 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 413999008741 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 150.9, E-value 2.3e-42 413999008742 PS01305 moaA / nifB / pqqE family signature. 413999008743 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; Provisional; Region: PRK14498 413999008744 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 413999008745 dimer interface [polypeptide binding]; other site 413999008746 putative functional site; other site 413999008747 putative MPT binding site; other site 413999008748 PBP superfamily domain; Region: PBP_like; pfam12727 413999008749 Pfam match to entry PF03454 MoeA_C, MoeA C-terminal region (domain IV), score 76.7, E-value 5.2e-20 413999008750 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain, score 192.3, E-value 8e-55 413999008751 PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 413999008752 Pfam match to entry PF03453 MoeA_N, MoeA N-terminal region (domain I and II), score 124.6, E-value 2e-34 413999008753 Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303 413999008754 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 413999008755 dimer interface [polypeptide binding]; other site 413999008756 putative functional site; other site 413999008757 putative MPT binding site; other site 413999008758 Pfam match to entry PF03454 MoeA_C, MoeA C-terminal region (domain IV), score 30.4, E-value 4.5e-06 413999008759 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain, score 179.2, E-value 6.9e-51 413999008760 PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 413999008761 Pfam match to entry PF03453 MoeA_N, MoeA N-terminal region (domain I and II), score 186.9, E-value 3.5e-53 413999008762 MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886 413999008763 MPT binding site; other site 413999008764 trimer interface [polypeptide binding]; other site 413999008765 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain, score 159.4, E-value 6.3e-45 413999008766 phosphate ABC transporter, ATP-binding protein; Region: 3a0107s01c2; TIGR00972 413999008767 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 413999008768 Walker A/P-loop; other site 413999008769 ATP binding site [chemical binding]; other site 413999008770 Q-loop/lid; other site 413999008771 ABC transporter signature motif; other site 413999008772 Walker B; other site 413999008773 D-loop; other site 413999008774 H-loop/switch region; other site 413999008775 Pfam match to entry PF00005 ABC_tran, ABC transporter score 168.1, E-value 1.5e-47 413999008776 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008777 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999008778 dimer interface [polypeptide binding]; other site 413999008779 conserved gate region; other site 413999008780 putative PBP binding loops; other site 413999008781 ABC-ATPase subunit interface; other site 413999008782 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 19.6, E-value 0.00051 413999008783 4 probable transmembrane helices predicted for CBO1945 by TMHMM2.0 at aa 26-48, 61-78, 93-115 and 197-219 413999008784 PBP superfamily domain; Region: PBP_like_2; pfam12849 413999008785 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 28.5, E-value 1.7e-05 413999008786 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999008787 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138 413999008788 putative efflux protein, MATE family; Region: matE; TIGR00797 413999008789 10 probable transmembrane helices predicted for CBO1947 by TMHMM2.0 at aa 58-80, 95-117, 138-157, 167-189,194-216, 257-279, 316-338, 358-377, 390-412 and 417-439 413999008790 Pfam match to entry PF01554 MatE, MatE, score 97.9,E-value 2.2e-26 413999008791 Pfam match to entry PF01554 MatE, MatE, score 123.1, E-value 5.3e-34 413999008792 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 413999008793 6 probable transmembrane helices predicted for CBO1949 by TMHMM2.0 at aa 7-29, 49-71, 78-100, 130-152,159-181 and 186-208 413999008794 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999008795 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999008796 Walker A/P-loop; other site 413999008797 ATP binding site [chemical binding]; other site 413999008798 Q-loop/lid; other site 413999008799 ABC transporter signature motif; other site 413999008800 Walker B; other site 413999008801 D-loop; other site 413999008802 H-loop/switch region; other site 413999008803 Pfam match to entry PF00005 ABC_tran, ABC transporter score 169.3, E-value 6.8e-48 413999008804 PS00211 ABC transporters family signature. 413999008805 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008806 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 413999008807 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 413999008808 FtsX-like permease family; Region: FtsX; pfam02687 413999008809 Pfam match to entry PF02687 FtsX, Predicted permease, score 58.1, E-value 2e-14 413999008810 4 probable transmembrane helices predicted for CBO1951 by TMHMM2.0 at aa 20-42, 322-343, 363-385 and 455-477 413999008811 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999008812 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999008813 ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254 413999008814 Walker A/P-loop; other site 413999008815 ATP binding site [chemical binding]; other site 413999008816 Q-loop/lid; other site 413999008817 ABC transporter signature motif; other site 413999008818 Walker B; other site 413999008819 D-loop; other site 413999008820 H-loop/switch region; other site 413999008821 Pfam match to entry PF00005 ABC_tran, ABC transporter score 207.5, E-value 2.2e-59 413999008822 PS00211 ABC transporters family signature. 413999008823 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008824 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 139.4, E-value 6.7e-39 413999008825 5 probable transmembrane helices predicted for CBO1952 by TMHMM2.0 at aa 20-42, 68-90, 144-161, 165-187 and 255-277 413999008826 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999008827 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999008828 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999008829 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999008830 Walker A/P-loop; other site 413999008831 ATP binding site [chemical binding]; other site 413999008832 Q-loop/lid; other site 413999008833 ABC transporter signature motif; other site 413999008834 Walker B; other site 413999008835 D-loop; other site 413999008836 H-loop/switch region; other site 413999008837 Pfam match to entry PF00005 ABC_tran, ABC transporter score 160.6, E-value 2.7e-45 413999008838 PS00211 ABC transporters family signature. 413999008839 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008840 6 probable transmembrane helices predicted for CBO1953 by TMHMM2.0 at aa 16-38, 53-75, 128-150, 154-176,237-259 and 274-296 413999008841 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 122.8, E-value 6.9e-34 413999008842 Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782 413999008843 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999008844 DNA binding residues [nucleotide binding] 413999008845 dimer interface [polypeptide binding]; other site 413999008846 GyrI-like small molecule binding domain; Region: GyrI-like; cl01368 413999008847 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 47.5, E-value 3.2e-11 413999008848 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999008849 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 413999008850 Pfam match to entry PF03358 FMN_red,NADPH-dependent FMN reductase, score 16.6, E-value 1.1e-07 413999008851 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999008852 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999008853 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 16.5, E-value 0.069 413999008854 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 17.0, E-value 0.048 413999008855 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 21.4, E-value 0.0023 413999008856 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 13.1, E-value 0.71 413999008857 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 10.6, E-value 3.8 413999008858 M6 family metalloprotease domain; Region: M6dom_TIGR03296 413999008859 chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214 413999008860 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999008861 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain, score 35.0, E-value 1.8e-07 413999008862 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829 413999008863 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999008864 Walker A motif; other site 413999008865 ATP binding site [chemical binding]; other site 413999008866 Walker B motif; other site 413999008867 arginine finger; other site 413999008868 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999008869 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 391.0, E-value 1.2e-114 413999008870 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999008871 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999008872 Glutaredoxin-related protein [Posttranslational modification, protein turnover, chaperones]; Region: COG4545 413999008873 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 413999008874 homotrimer interaction site [polypeptide binding]; other site 413999008875 putative active site [active] 413999008876 Pfam match to entry PF01042 ribonuc_L-PSP,Endoribonuclease L-PSP, score 192.6, E-value 6.4e-55 413999008877 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 413999008878 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 413999008879 Pfam match to entry PF00375 SDF,Sodium:dicarboxylate symporter family, score 116.4,E-value 5.7e-32 413999008880 8 probable transmembrane helices predicted for CBO1962 by TMHMM2.0 at aa 13-30, 45-67, 80-102, 145-164,184-203, 218-240, 327-349 and 354-376 413999008881 putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350 413999008882 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999008883 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999008884 homodimer interface [polypeptide binding]; other site 413999008885 catalytic residue [active] 413999008886 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 28.0, E-value 3.3e-07 413999008887 L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681 413999008888 Pfam match to entry PF06354 DUF1063, Protein of unknown function (DUF1063), score 427.8, E-value 9.9e-126 413999008889 Predicted helix-turn-helix motif with score 1035.000, SD 2.71 at aa 273-294, sequence LPVTEMARYLNSSREQLVKALA 413999008890 Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309 413999008891 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999008892 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999008893 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999008894 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 17.8, E-value 0.027 413999008895 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 17.1, E-value 0.045 413999008896 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 16.4, E-value 0.073 413999008897 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 12.2, E-value 1.3 413999008898 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 14.0, E-value 0.37 413999008899 M6 family metalloprotease domain; Region: M6dom_TIGR03296 413999008900 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999008901 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304 413999008902 dimerization interface [polypeptide binding]; other site 413999008903 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999008904 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999008905 dimer interface [polypeptide binding]; other site 413999008906 phosphorylation site [posttranslational modification] 413999008907 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999008908 ATP binding site [chemical binding]; other site 413999008909 Mg2+ binding site [ion binding]; other site 413999008910 G-X-G motif; other site 413999008911 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 112.0, E-value 1.2e-30 413999008912 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 49.6, E-value 7.2e-12 413999008913 Pfam match to entry PF00672 HAMP, HAMP domain,score 61.0, E-value 2.7e-15 413999008914 2 probable transmembrane helices predicted for CBO1967 by TMHMM2.0 at aa 15-37 and 158-180 413999008915 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999008916 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999008917 active site 413999008918 phosphorylation site [posttranslational modification] 413999008919 intermolecular recognition site; other site 413999008920 dimerization interface [polypeptide binding]; other site 413999008921 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999008922 DNA binding site [nucleotide binding] 413999008923 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 87.7, E-value 2.4e-23 413999008924 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 118.4, E-value 1.4e-32 413999008925 Uncharacterized ArCR, COG2043; Region: DUF169; pfam02596 413999008926 Pfam match to entry PF02596 DUF169, Uncharacterized ArCR, COG2043, score 97.8, E-value 2.2e-26 413999008927 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 413999008928 4 probable transmembrane helices predicted for CBO1970 by TMHMM2.0 at aa 7-40, 55-72, 79-100 and 211-233 413999008929 Pfam match to entry PF02361 CbiQ, Cobalt transport protein, score 55.1, E-value 1.6e-13 413999008930 ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123 413999008931 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 413999008932 Walker A/P-loop; other site 413999008933 ATP binding site [chemical binding]; other site 413999008934 Q-loop/lid; other site 413999008935 ABC transporter signature motif; other site 413999008936 Walker B; other site 413999008937 D-loop; other site 413999008938 H-loop/switch region; other site 413999008939 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 413999008940 Walker A/P-loop; other site 413999008941 ATP binding site [chemical binding]; other site 413999008942 Q-loop/lid; other site 413999008943 ABC transporter signature motif; other site 413999008944 Walker B; other site 413999008945 D-loop; other site 413999008946 H-loop/switch region; other site 413999008947 Pfam match to entry PF00005 ABC_tran, ABC transporter score 180.2, E-value 3.4e-51 413999008948 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008949 Pfam match to entry PF00005 ABC_tran, ABC transporter score 155.8, E-value 8.1e-44 413999008950 PS00211 ABC transporters family signature. 413999008951 PS00017 ATP/GTP-binding site motif A (P-loop). 413999008952 ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819 413999008953 5 probable transmembrane helices predicted for CBO1972 by TMHMM2.0 at aa 10-27, 39-61, 84-106, 113-135 and 145-167 413999008954 Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457 413999008955 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815 413999008956 dimer interface [polypeptide binding]; other site 413999008957 active site 413999008958 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999008959 substrate binding site [chemical binding]; other site 413999008960 catalytic residue [active] 413999008961 Pfam match to entry PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain, score 74.1, E-value 3.1e-19 413999008962 Spore germination protein; Region: Spore_permease; cl17796 413999008963 Pfam match to entry PF03845 Spore_permease, Spore germination protein, score 312.0, E-value 7.2e-91 413999008964 11 probable transmembrane helices predicted for CBO1974 by TMHMM2.0 at aa 13-35, 42-64, 79-101, 113-135,148-170, 191-208, 221-243, 248-267, 272-294, 306-323 and 338-355 413999008965 Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323 413999008966 Pfam match to entry PF03323 GerA,Bacillus/Clostridium GerA spore germination protein, score 499.2, E-value 3.4e-147 413999008967 3 probable transmembrane helices predicted for CBO1975 by TMHMM2.0 at aa 290-312, 382-404 and 417-439 413999008968 Spore germination protein; Region: Spore_permease; cl17796 413999008969 Pfam match to entry PF03845 Spore_permease, Spore germination protein, score 251.0, E-value 1.8e-72 413999008970 10 probable transmembrane helices predicted for CBO1976 by TMHMM2.0 at aa 13-32, 42-63, 83-105, 115-137,149-171, 191-208, 221-243, 253-275, 305-324 and 334-356 413999008971 PS00012 Phosphopantetheine attachment site. 413999008972 germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887 413999008973 Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504 413999008974 1 probable transmembrane helix predicted for CBO1977 by TMHMM2.0 at aa 9-31 413999008975 Pfam match to entry PF05504 Spore_GerAC, Spore germination B3/ GerAC like, C-terminal, score 133.8,E-value 3.2e-37 413999008976 Spore germination protein; Region: Spore_permease; cl17796 413999008977 Pfam match to entry PF03845 Spore_permease, Spore germination protein, score 269.9, E-value 3.6e-78 413999008978 10 probable transmembrane helices predicted for CBO1978 by TMHMM2.0 at aa 13-32, 42-64, 85-107, 122-139,146-165, 191-208, 221-243, 248-270, 305-324 and 334-353 413999008979 PS00012 Phosphopantetheine attachment site. 413999008980 Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719 413999008981 1 probable transmembrane helix predicted for CBO1979 by TMHMM2.0 at aa 40-62 413999008982 1 probable transmembrane helix predicted for CBO1980 by TMHMM2.0 at aa 15-32 413999008983 alkylhydroperoxidase/carboxymuconolactone decarboxylase family protein; Region: perox_w_seleSAM; TIGR04169 413999008984 Pfam match to entry PF02627 CMD,Carboxymuconolactone decarboxylase, score 77.5,E-value 2.9e-20 413999008985 radical SAM/Cys-rich domain protein; Region: rSAM_SeCys; TIGR04167 413999008986 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999008987 FeS/SAM binding site; other site 413999008988 Protein of unknown function (DUF3641); Region: DUF3641; pfam12345 413999008989 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 29.5, E-value 8.2e-06 413999008990 PS00190 Cytochrome c family heme-binding site signature. 413999008991 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999008992 binding surface 413999008993 TPR repeat; Region: TPR_11; pfam13414 413999008994 TPR motif; other site 413999008995 Tetratricopeptide repeat; Region: TPR_16; pfam13432 413999008996 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999008997 binding surface 413999008998 TPR motif; other site 413999008999 TPR repeat; Region: TPR_11; pfam13414 413999009000 Pfam match to entry PF00515 TPR, TPR Domain, score 42.5, E-value 9.6e-10 413999009001 Pfam match to entry PF00515 TPR, TPR Domain, score 14.3, E-value 0.074 413999009002 Pfam match to entry PF00515 TPR, TPR Domain, score 13.3, E-value 0.097 413999009003 Pfam match to entry PF00515 TPR, TPR Domain, score 35.9, E-value 9.4e-08 413999009004 Pfam match to entry PF00515 TPR, TPR Domain, score 32.8, E-value 8.1e-07 413999009005 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 413999009006 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 413999009007 TrkA-C domain; Region: TrkA_C; pfam02080 413999009008 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 54.5, E-value 2.5e-13 413999009009 Pfam match to entry PF00999 Na_H_Exchanger,Sodium/hydrogen exchanger family, score 191.0, E-value 2e-54 413999009010 10 probable transmembrane helices predicted for CBO1984 by TMHMM2.0 at aa 20-39, 54-76, 88-110, 160-182,187-205, 220-242, 263-285, 295-317, 330-352 and 356-378 413999009011 heat shock protein 90; Provisional; Region: PRK05218 413999009012 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999009013 ATP binding site [chemical binding]; other site 413999009014 Mg2+ binding site [ion binding]; other site 413999009015 G-X-G motif; other site 413999009016 Pfam match to entry PF00183 HSP90, Hsp90 protein,score 593.1, E-value 1.7e-175 413999009017 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 20.4,E-value 0.00054 413999009018 PS00298 Heat shock hsp90 proteins family signature. 413999009019 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999009020 Walker A/P-loop; other site 413999009021 ATP binding site [chemical binding]; other site 413999009022 Q-loop/lid; other site 413999009023 ABC transporter signature motif; other site 413999009024 Walker B; other site 413999009025 D-loop; other site 413999009026 H-loop/switch region; other site 413999009027 1 probable transmembrane helix predicted for CBO1986 by TMHMM2.0 at aa 134-156 413999009028 Pfam match to entry PF00488 MutS_V, MutS domain V,score -35.4, E-value 1.1e-11 413999009029 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009030 PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992 413999009031 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999009032 active site turn [active] 413999009033 phosphorylation site [posttranslational modification] 413999009034 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999009035 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 55.0, E-value 1.7e-13 413999009036 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999009037 10 probable transmembrane helices predicted for CBO1987 by TMHMM2.0 at aa 105-127, 158-180, 189-211,226-248, 260-282, 302-324, 344-366, 376-395, 400-422 and 442-464 413999009038 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 127.1, E-value 3.4e-35 413999009039 alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403 413999009040 Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333 413999009041 Ca binding site [ion binding]; other site 413999009042 active site 413999009043 catalytic site [active] 413999009044 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain, score 427.8, E-value 1e-125 413999009045 trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404 413999009046 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999009047 DNA-binding site [nucleotide binding]; DNA binding site 413999009048 UTRA domain; Region: UTRA; pfam07702 413999009049 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 61.6, E-value 1.8e-15 413999009050 Predicted helix-turn-helix motif with score 1087.000, SD 2.89 at aa 28-49, sequence SSENEMMKEYNVSRDTIRKALN 413999009051 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 413999009052 active site 413999009053 phosphorylation site [posttranslational modification] 413999009054 Pfam match to entry PF00359 PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2, score 73.8, E-value 3.7e-19 413999009055 PS00372 PTS EIIA domains phosphorylation site signature 2. 413999009056 putative PTS system transporter subunits IIBC; Provisional; Region: PRK11404 413999009057 PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569 413999009058 active site 413999009059 P-loop; other site 413999009060 phosphorylation site [posttranslational modification] 413999009061 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299 413999009062 8 probable transmembrane helices predicted for CBO1991 by TMHMM2.0 at aa 139-161, 176-198, 211-233,258-280, 300-317, 337-359, 395-417 and 437-456 413999009063 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 129.7, E-value 5.7e-36 413999009064 Pfam match to entry PF02379 PTS_IIB_fruc, PTS system, Fructose specific IIB subunit, score 181.7,E-value 1.2e-51 413999009065 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105 413999009066 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 413999009067 putative substrate binding site [chemical binding]; other site 413999009068 putative ATP binding site [chemical binding]; other site 413999009069 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 119.5, E-value 6.4e-33 413999009070 PS00152 ATP synthase alpha and beta subunits signature. 413999009071 Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947 413999009072 fructose-bisphosphate aldolase; Provisional; Region: PRK09197 413999009073 intersubunit interface [polypeptide binding]; other site 413999009074 active site 413999009075 zinc binding site [ion binding]; other site 413999009076 Na+ binding site [ion binding]; other site 413999009077 Pfam match to entry PF01116 F_bP_aldolase,Fructose-bisphosphate aldolase class-II, score 437.9,E-value 9.3e-129 413999009078 PS00806 Fructose-bisphosphate aldolase class-II signature 2. 413999009079 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 413999009080 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 413999009081 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 413999009082 putative active site [active] 413999009083 Pfam match to entry PF01380 SIS, SIS domain, score 26.8, E-value 5.3e-05 413999009084 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family, score 24.3, E-value 5.4e-07 413999009085 Predicted helix-turn-helix motif with score 1592.000, SD 4.61 at aa 34-55, sequence MSIVDVAEKSFTSPATVSRTIK 413999009086 Protein of unknown function (DUF2992); Region: DUF2992; pfam11208 413999009087 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 413999009088 homotrimer interaction site [polypeptide binding]; other site 413999009089 putative active site [active] 413999009090 Pfam match to entry PF01042 ribonuc_L-PSP,Endoribonuclease L-PSP, score 45.5, E-value 1.2e-10 413999009091 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999009092 Radical SAM superfamily; Region: Radical_SAM; pfam04055 413999009093 FeS/SAM binding site; other site 413999009094 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 81.0, E-value 2.6e-21 413999009095 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009096 Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371 413999009097 Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170 413999009098 dimer interface [polypeptide binding]; other site 413999009099 active site 413999009100 metal binding site [ion binding]; metal-binding site 413999009101 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 266.0, E-value 5.2e-77 413999009102 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999009103 dimerization interface [polypeptide binding]; other site 413999009104 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999009105 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999009106 dimer interface [polypeptide binding]; other site 413999009107 putative CheW interface [polypeptide binding]; other site 413999009108 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 151.1, E-value 2.1e-42 413999009109 Pfam match to entry PF00672 HAMP, HAMP domain,score 60.3, E-value 4.3e-15 413999009110 2 probable transmembrane helices predicted for CBO2000 by TMHMM2.0 at aa 10-32 and 168-190 413999009111 Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457 413999009112 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815 413999009113 active site 413999009114 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999009115 dimer interface [polypeptide binding]; other site 413999009116 substrate binding site [chemical binding]; other site 413999009117 catalytic residue [active] 413999009118 Pfam match to entry PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain, score 24.7, E-value 4.9e-07 413999009119 ATP cone domain; Region: ATP-cone; pfam03477 413999009120 Pfam match to entry PF03477 ATP-cone, ATP cone domain, score 20.5, E-value 6.7e-05 413999009121 putative oxidoreductase; Provisional; Region: PRK11579 413999009122 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 413999009123 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 413999009124 Pfam match to entry PF01408 GFO_IDH_MocA,Oxidoreductase, NAD-binding Rossmann fold, score 126.3, E-value 6e-35 413999009125 Pfam match to entry PF02894 GFO_IDH_MocA_C,Oxidoreductase, C-terminal alpha/beta domain, score 59.4, E-value 8e-15 413999009126 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999009127 active site 413999009128 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 40.6, E-value 3.7e-09 413999009129 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 413999009130 10 probable transmembrane helices predicted for CBO2006 by TMHMM2.0 at aa 7-29, 34-56, 76-95, 100-122,129-146, 150-168, 189-211, 262-284, 291-313 and 328-350 413999009131 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999009132 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999009133 metal binding site [ion binding]; metal-binding site 413999009134 active site 413999009135 I-site; other site 413999009136 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 94.0, E-value 3.1e-25 413999009137 L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681 413999009138 Pfam match to entry PF06354 DUF1063, Protein of unknown function (DUF1063), score 398.8, E-value 5.6e-117 413999009139 1 probable transmembrane helix predicted for CBO2008 by TMHMM2.0 at aa 316-338 413999009140 PAS domain; Region: PAS; smart00091 413999009141 phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608 413999009142 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999009143 Walker A motif; other site 413999009144 ATP binding site [chemical binding]; other site 413999009145 Walker B motif; other site 413999009146 arginine finger; other site 413999009147 Predicted helix-turn-helix motif with score 1687.000, SD 4.93 at aa 564-585, sequence KGKERIAKELDINLSTLYRKLN 413999009148 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999009149 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 419.8, E-value 2.7e-123 413999009150 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999009151 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999009152 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 413999009153 DEAD-like helicases superfamily; Region: DEXDc; smart00487 413999009154 ATP binding site [chemical binding]; other site 413999009155 Mg++ binding site [ion binding]; other site 413999009156 motif III; other site 413999009157 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999009158 nucleotide binding region [chemical binding]; other site 413999009159 ATP-binding site [chemical binding]; other site 413999009160 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 280.6, E-value 2.1e-81 413999009161 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009162 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 413999009163 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 129.4, E-value 7.1e-36 413999009164 Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340 413999009165 SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379 413999009166 Pfam match to entry PF00188 SCP, SCP-like extracellular protein, score 99.6, E-value 6.5e-27 413999009167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999009168 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999009169 DNA-binding site [nucleotide binding]; DNA binding site 413999009170 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999009171 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999009172 homodimer interface [polypeptide binding]; other site 413999009173 catalytic residue [active] 413999009174 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 25.7, E-value 0.0001 413999009175 EamA-like transporter family; Region: EamA; pfam00892 413999009176 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 413999009177 EamA-like transporter family; Region: EamA; pfam00892 413999009178 10 probable transmembrane helices predicted for CBO2013 by TMHMM2.0 at aa 9-26, 41-60, 72-94, 99-118,123-142, 152-171, 183-205, 220-242, 255-274 and 279-298 413999009179 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 95.4, E-value 1.2e-25 413999009180 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 80.5, E-value 3.7e-21 413999009181 aspartate aminotransferase; Provisional; Region: PRK06348 413999009182 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999009183 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999009184 homodimer interface [polypeptide binding]; other site 413999009185 catalytic residue [active] 413999009186 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 160.8, E-value 2.5e-45 413999009187 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 413999009188 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 413999009189 Walker A/P-loop; other site 413999009190 ATP binding site [chemical binding]; other site 413999009191 Q-loop/lid; other site 413999009192 ABC transporter signature motif; other site 413999009193 Walker B; other site 413999009194 D-loop; other site 413999009195 H-loop/switch region; other site 413999009196 Pfam match to entry PF00005 ABC_tran, ABC transporter score 220.7, E-value 2.2e-63 413999009197 PS00211 ABC transporters family signature. 413999009198 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009199 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 413999009200 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999009201 dimer interface [polypeptide binding]; other site 413999009202 conserved gate region; other site 413999009203 putative PBP binding loops; other site 413999009204 ABC-ATPase subunit interface; other site 413999009205 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 126.8, E-value 4.3e-35 413999009206 5 probable transmembrane helices predicted for CBO2017 by TMHMM2.0 at aa 20-39, 59-81, 96-118, 154-176 and 196-218 413999009207 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999009208 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 413999009209 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 413999009210 substrate binding pocket [chemical binding]; other site 413999009211 membrane-bound complex binding site; other site 413999009212 hinge residues; other site 413999009213 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3, score 225.1, E-value 1.1e-64 413999009214 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009215 Domain of unknown function (DUF2088); Region: DUF2088; pfam09861 413999009216 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075 413999009217 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999009218 catalytic residue [active] 413999009219 Pfam match to entry PF00266 aminotran_5,Aminotransferase class-V, score 28.8, E-value 7.3e-12 413999009220 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 413999009221 Chloramphenicol acetyltransferase; Region: CAT; cl02008 413999009222 Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845 413999009223 Pfam match to entry PF00302 CAT, Chloramphenicol acetyltransferase, score 409.1, E-value 4.3e-120 413999009224 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082); Region: DUF2082; pfam09855 413999009225 Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901 413999009226 AAA domain; Region: AAA_12; pfam13087 413999009227 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 413999009228 1 probable transmembrane helix predicted for CBO2026 by TMHMM2.0 at aa 90-112 413999009229 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999009230 sequence-specific DNA binding site [nucleotide binding]; other site 413999009231 salt bridge; other site 413999009232 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 29.3, E-value 9.2e-06 413999009233 Predicted helix-turn-helix motif with score 1915.000, SD 5.71 at aa 1-22, sequence MKQEDLAKLVGVRRETIGHLEN 413999009234 Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104 413999009235 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999009236 putative substrate translocation pore; other site 413999009237 POT family; Region: PTR2; cl17359 413999009238 11 probable transmembrane helices predicted for CBO2028 by TMHMM2.0 at aa 21-40, 55-72, 79-98, 103-120,141-163, 167-189, 229-251, 314-331, 338-360, 375-397 and 410-427 413999009239 Pfam match to entry PF00854 PTR2, POT family, score -10.0, E-value 1e-08 413999009240 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999009241 POT family; Region: PTR2; cl17359 413999009242 13 probable transmembrane helices predicted for CBO2029 by TMHMM2.0 at aa 9-26, 30-49, 56-73, 77-99,106-128, 143-165, 172-194, 231-253, 274-296, 316-333,340-362, 377-399 and 406-428 413999009243 Pfam match to entry PF00854 PTR2, POT family, score 0.0, E-value 3.1e-09 413999009244 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 413999009245 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 413999009246 Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092 413999009247 active site 413999009248 Pfam match to entry PF00557 Peptidase_M24,metallopeptidase M24, score 186.3, E-value 5.1e-53 413999009249 proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250 413999009250 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold, score 76.8, E-value 4.6e-20 413999009251 1 probable transmembrane helix predicted for CBO2032 by TMHMM2.0 at aa 13-35 413999009252 uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain; Region: SLC6sbd_u1; cd10334 413999009253 Na2 binding site [ion binding]; other site 413999009254 putative substrate binding site 1 [chemical binding]; other site 413999009255 Na binding site 1 [ion binding]; other site 413999009256 putative substrate binding site 2 [chemical binding]; other site 413999009257 Pfam match to entry PF00209 SNF,Sodium:neurotransmitter symporter family, score 326.6,E-value 3e-95 413999009258 13 probable transmembrane helices predicted for CBO2033 by TMHMM2.0 at aa 12-34, 44-66, 86-108, 144-166,179-201, 221-240, 261-283, 293-315, 320-342, 357-379,386-408, 428-450 and 462-484 413999009259 PS00610 Sodium:neurotransmitter symporter family signature 1. 413999009260 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999009261 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999009262 DNA-binding site [nucleotide binding]; DNA binding site 413999009263 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999009264 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999009265 homodimer interface [polypeptide binding]; other site 413999009266 catalytic residue [active] 413999009267 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 25.2, E-value 5.9e-07 413999009268 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 54.8, E-value 2e-13 413999009269 Predicted helix-turn-helix motif with score 1909.000, SD 5.69 at aa 48-69, sequence PPQRELADYLDINLSTITRAFK 413999009270 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 413999009271 Pfam match to entry PF02567 PhzC-PhzF, Phenazine biosynthesis-like protein, score 199.1, E-value 7.2e-57 413999009272 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199 413999009273 homotrimer interaction site [polypeptide binding]; other site 413999009274 putative active site [active] 413999009275 Pfam match to entry PF01042 ribonuc_L-PSP,Endoribonuclease L-PSP, score 31.5, E-value 1.4e-07 413999009276 1 probable transmembrane helix predicted for CBO2037 by TMHMM2.0 at aa 16-38 413999009277 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 413999009278 nucleophilic elbow; other site 413999009279 catalytic triad; other site 413999009280 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 9.3, E-value 2.1 413999009281 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 2.2, E-value 55 413999009282 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 6.0, E-value 9.8 413999009283 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 2.4, E-value 51 413999009284 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 6.1, E-value 9 413999009285 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 1.2, E-value 87 413999009286 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 4.9, E-value 16 413999009287 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 4.2, E-value 22 413999009288 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 0.8, E-value 1.1e+02 413999009289 Pfam match to entry PF02412 tsp_3, Thrombospondin type 3 repeat, score 3.1, E-value 37 413999009290 1 probable transmembrane helix predicted for CBO2038 by TMHMM2.0 at aa 17-36 413999009291 NAD(P)H:flavin oxidoreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150 413999009292 putative FMN binding site [chemical binding]; other site 413999009293 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 151.2, E-value 1.9e-42 413999009294 PS00904 Protein prenyltransferases alpha subunit repeat signature. 413999009295 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198 413999009296 metal ion-dependent adhesion site (MIDAS); other site 413999009297 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 413999009298 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009299 myosin-cross-reactive antigen; Provisional; Region: PRK13977 413999009300 Pfam match to entry PF06100 Strep_67kDa_ant,Streptococcal 67 kDa myosin-cross-reactive antigen like family, score 1267.7, E-value 0 413999009301 PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature. 413999009302 1 probable transmembrane helix predicted for CBO2043 by TMHMM2.0 at aa 34-56 413999009303 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009304 probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366 413999009305 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999009306 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 26.8, E-value 5.5e-05 413999009307 Predicted helix-turn-helix motif with score 1190.000, SD 3.24 at aa 26-47, sequence ITVKDIATACEINRNTFYYYYT 413999009308 Phage protein Gp37/Gp68; Region: Gp37_Gp68; cl15384 413999009309 Pfam match to entry PF00239 resolvase, Resolvase, N terminal domain, score 41.5, E-value 2e-09 413999009310 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 413999009311 active site 413999009312 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 60.7, E-value 3.3e-15 413999009313 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 413999009314 active site 413999009315 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 29.3, E-value 9.6e-06 413999009316 Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360 413999009317 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570 413999009318 putative trimer interface [polypeptide binding]; other site 413999009319 putative CoA binding site [chemical binding]; other site 413999009320 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 5.1,E-value 24 413999009321 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 15.1,E-value 0.18 413999009322 PS00101 Hexapeptide-repeat containing-transferases signature. 413999009323 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 21.5,E-value 0.0022 413999009324 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 2.7,E-value 45 413999009325 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 2.5,E-value 9.6 413999009326 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 413999009327 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 413999009328 inhibitor-cofactor binding pocket; inhibition site 413999009329 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999009330 catalytic residue [active] 413999009331 Pfam match to entry PF01041 DegT_DnrJ_EryC1,DegT/DnrJ/EryC1/StrS aminotransferase, score 320.7,E-value 1.7e-93 413999009332 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 413999009333 Predicted glycosyltransferases [General function prediction only]; Region: COG1216 413999009334 active site 413999009335 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 51.2, E-value 2.5e-12 413999009336 G1P_TT_long represents the long form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_long; cd04189 413999009337 glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208 413999009338 substrate binding site; other site 413999009339 metal-binding site 413999009340 Oligomer interface; other site 413999009341 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 413999009342 Pfam match to entry PF00483 NTP_transferase,Nucleotidyl transferase, score 264.4, E-value 1.6e-76 413999009343 dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246 413999009344 dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088 413999009345 NAD binding site [chemical binding]; other site 413999009346 substrate binding site [chemical binding]; other site 413999009347 homodimer interface [polypeptide binding]; other site 413999009348 active site 413999009349 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase, score 495.4,E-value 4.6e-146 413999009350 Domain of unknown function (DUF4342); Region: DUF4342; pfam14242 413999009351 Domain of unknown function (DUF4342); Region: DUF4342; pfam14242 413999009352 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 413999009353 PGAP1-like protein; Region: PGAP1; pfam07819 413999009354 PS00120 Lipases, serine active site. 413999009355 1 probable transmembrane helix predicted for CBO2061 by TMHMM2.0 at aa 9-28 413999009356 VanZ like family; Region: VanZ; pfam04892 413999009357 6 probable transmembrane helices predicted for CBO2062 by TMHMM2.0 at aa 15-37, 58-80, 106-128, 137-155,165-187 and 200-222 413999009358 Pfam match to entry PF04892 VanZ, VanZ like family,score 115.0, E-value 1.5e-31 413999009359 Protein of unknown function (DUF4065); Region: DUF4065; pfam13274 413999009360 ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346 413999009361 6 probable transmembrane helices predicted for CBO2064 by TMHMM2.0 at aa 12-34, 38-60, 88-110, 115-137,149-171 and 181-203 413999009362 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999009363 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999009364 Walker A/P-loop; other site 413999009365 ATP binding site [chemical binding]; other site 413999009366 Q-loop/lid; other site 413999009367 ABC transporter signature motif; other site 413999009368 Walker B; other site 413999009369 D-loop; other site 413999009370 H-loop/switch region; other site 413999009371 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009372 Pfam match to entry PF00005 ABC_tran, ABC transporter score 137.4, E-value 2.7e-38 413999009373 PS00211 ABC transporters family signature. 413999009374 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009375 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999009376 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999009377 DNA-binding site [nucleotide binding]; DNA binding site 413999009378 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 64.6, E-value 2.1e-16 413999009379 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 413999009380 glycosyltransferase, MGT family; Region: MGT; TIGR01426 413999009381 active site 413999009382 TDP-binding site; other site 413999009383 acceptor substrate-binding pocket; other site 413999009384 homodimer interface [polypeptide binding]; other site 413999009385 Pfam match to entry PF00201 UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase, score 29.4, E-value 1.5e-08 413999009386 Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002 413999009387 looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439 413999009388 Pfam match to entry PF04014 SpoVT_AbrB, SpoVT / AbrB like domain, score 25.4, E-value 0.00014 413999009389 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 413999009390 iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525 413999009391 PS00764 Endonuclease III iron-sulfur binding region signature. 413999009392 cytosine deaminase; Provisional; Region: PRK09230 413999009393 Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293 413999009394 active site 413999009395 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score -22.3, E-value 0.0083 413999009396 nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484 413999009397 Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133 413999009398 Na binding site [ion binding]; other site 413999009399 putative substrate binding site [chemical binding]; other site 413999009400 Pfam match to entry PF02133 Transp_cyt_pur,Permease for cytosine/purines, uracil, thiamine,allantoin, score 216.7, E-value 3.6e-62 413999009401 12 probable transmembrane helices predicted for CBO2073 by TMHMM2.0 at aa 23-42, 57-79, 100-122, 127-149,156-175, 195-214, 227-249, 259-281, 306-323, 328-350,363-380 and 385-404 413999009402 Radical SAM superfamily; Region: Radical_SAM; pfam04055 413999009403 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999009404 FeS/SAM binding site; other site 413999009405 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 45.2, E-value 1.6e-10 413999009406 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 413999009407 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 413999009408 Walker A/P-loop; other site 413999009409 ATP binding site [chemical binding]; other site 413999009410 Q-loop/lid; other site 413999009411 ABC transporter signature motif; other site 413999009412 Walker B; other site 413999009413 D-loop; other site 413999009414 H-loop/switch region; other site 413999009415 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 413999009416 Second domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain2; cd03226 413999009417 Walker A/P-loop; other site 413999009418 ATP binding site [chemical binding]; other site 413999009419 Q-loop/lid; other site 413999009420 ABC transporter signature motif; other site 413999009421 Walker B; other site 413999009422 D-loop; other site 413999009423 H-loop/switch region; other site 413999009424 Pfam match to entry PF00005 ABC_tran, ABC transporter score 135.8, E-value 8.1e-38 413999009425 PS00211 ABC transporters family signature. 413999009426 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009427 Pfam match to entry PF00005 ABC_tran, ABC transporter score 143.6, E-value 3.7e-40 413999009428 PS00211 ABC transporters family signature. 413999009429 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009430 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 413999009431 3 probable transmembrane helices predicted for CBO2078 by TMHMM2.0 at aa 34-56, 71-93 and 222-240 413999009432 Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; pfam09605 413999009433 5 probable transmembrane helices predicted for CBO2079 by TMHMM2.0 at aa 15-37, 42-64, 74-103, 115-137 and 166-188 413999009434 Helix-turn-helix domain; Region: HTH_18; pfam12833 413999009435 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999009436 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 18.0, E-value 0.023 413999009437 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 31.8, E-value 1.7e-06 413999009438 Protein of unknown function; Region: DUF3658; pfam12395 413999009439 Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247 413999009440 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999009441 Coenzyme A binding pocket [chemical binding]; other site 413999009442 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 49.9, E-value 5.8e-12 413999009443 The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425 413999009444 active site 413999009445 8-oxo-dGMP binding site [chemical binding]; other site 413999009446 nudix motif; other site 413999009447 metal binding site [ion binding]; metal-binding site 413999009448 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 68.8, E-value 1.2e-17 413999009449 PS00893 mutT domain signature. 413999009450 N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204 413999009451 PLD-like domain; Region: PLDc_2; pfam13091 413999009452 putative homodimer interface [polypeptide binding]; other site 413999009453 putative active site [active] 413999009454 catalytic site [active] 413999009455 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061 413999009456 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999009457 ATP binding site [chemical binding]; other site 413999009458 putative Mg++ binding site [ion binding]; other site 413999009459 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999009460 nucleotide binding region [chemical binding]; other site 413999009461 ATP-binding site [chemical binding]; other site 413999009462 Domain of unknown function (DUF3427); Region: DUF3427; pfam11907 413999009463 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 52.2, E-value 1.2e-12 413999009464 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 413999009465 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 15.8, E-value 4.6e-07 413999009466 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009467 Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210 413999009468 Part of AAA domain; Region: AAA_19; pfam13245 413999009469 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score -0.3, E-value 3.7e-11 413999009470 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009471 Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593 413999009472 TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family. The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026 413999009473 putative active site [active] 413999009474 putative metal-binding site [ion binding]; other site 413999009475 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain, score 32.6, E-value 4.3e-09 413999009476 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009477 Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; cl17861 413999009478 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 413999009479 active site 413999009480 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999009481 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999009482 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999009483 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708 413999009484 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 34.6, E-value 2.4e-07 413999009485 PS00041 Bacterial regulatory proteins, araC family signature. 413999009486 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 38.8, E-value 1.3e-08 413999009487 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 413999009488 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold, score 65.9, E-value 9.2e-17 413999009489 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 413999009490 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999009491 NAD(P) binding site [chemical binding]; other site 413999009492 active site 413999009493 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase, score 298.5,E-value 8.4e-87 413999009494 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 413999009495 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 413999009496 active site 413999009497 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 413999009498 active site 413999009499 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 145.3, E-value 1.1e-40 413999009500 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 65.2, E-value 1.4e-16 413999009501 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 413999009502 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 413999009503 active site 413999009504 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999009505 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 413999009506 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 116.5, E-value 5.5e-32 413999009507 Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168 413999009508 Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480 413999009509 G1 box; other site 413999009510 putative GEF interaction site [polypeptide binding]; other site 413999009511 GTP/Mg2+ binding site [chemical binding]; other site 413999009512 Switch I region; other site 413999009513 G2 box; other site 413999009514 G3 box; other site 413999009515 Switch II region; other site 413999009516 G4 box; other site 413999009517 G5 box; other site 413999009518 Tet_II: This subfamily represents domain II of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to domain II of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome...; Region: Tet_II; cd03690 413999009519 EF-G_domain IV_RPP domain is a part of bacterial ribosomal protected proteins (RPP) family. RPPs such as tetracycline resistance proteins Tet(M) and Tet(O) mediate tetracycline resistance in both gram-positive and -negative species. Tetracyclines inhibit...; Region: Tet_like_IV; cd01684 413999009520 Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711 413999009521 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus, score 72.3, E-value 1.1e-18 413999009522 Pfam match to entry PF03764 EFG_IV, Elongation factor G, domain IV, score 61.0, E-value 2.6e-15 413999009523 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 188.1, E-value 1.5e-53 413999009524 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009525 Domain of unknown function (DUF3472); Region: DUF3472; pfam11958 413999009526 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 413999009527 aromatic chitin/cellulose binding site residues [chemical binding]; other site 413999009528 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain, score 48.9, E-value 1.2e-11 413999009529 1 probable transmembrane helix predicted for CBO2105 by TMHMM2.0 at aa 5-22 413999009530 Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577 413999009531 1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059 413999009532 Hexamer interface [polypeptide binding]; other site 413999009533 Putative hexagonal pore residue; other site 413999009534 Pfam match to entry PF00936 Bact_microcomp,Bacterial microcompartments protein family, score 178.4,E-value 1.2e-50 413999009535 PS01139 Bacterial microcompartiments proteins signature. 413999009536 propanediol utilization phosphotransacylase; Provisional; Region: PRK15070 413999009537 Propanediol utilisation protein PduL; Region: PduL; pfam06130 413999009538 Propanediol utilisation protein PduL; Region: PduL; pfam06130 413999009539 Pfam match to entry PF06130 PduL, Propanediol utilisation protein PduL, score 316.5, E-value 3.3e-92 413999009540 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 413999009541 Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122 413999009542 putative catalytic cysteine [active] 413999009543 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase, score -195.2, E-value 4.6e-06 413999009544 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009545 Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577 413999009546 Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045 413999009547 Hexamer interface [polypeptide binding]; other site 413999009548 Hexagonal pore residue; other site 413999009549 Pfam match to entry PF00936 Bact_microcomp,Bacterial microcompartments protein family, score 128.5,E-value 1.3e-35 413999009550 ethanolamine utilization protein EutQ; Provisional; Region: PRK15457 413999009551 Ethanolamine utilisation protein EutQ; Region: EutQ; pfam06249 413999009552 Pfam match to entry PF06249 EutQ, Ethanolamine utilisation protein EutQ, score 107.4, E-value 2.9e-29 413999009553 Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614 413999009554 Hexamer/Pentamer interface [polypeptide binding]; other site 413999009555 central pore; other site 413999009556 Pfam match to entry PF03319 EutN_CcmL, Ethanolamine utilisation protein EutN/carboxysome structural protein Ccml, score 49.2, E-value 9.7e-12 413999009557 Bacterial Micro-Compartment (BMC)-like domain 2; Region: BMC_like_2; cd07055 413999009558 putative hexamer interface [polypeptide binding]; other site 413999009559 putative hexagonal pore; other site 413999009560 ethanolamine utilization protein EutJ; Provisional; Region: PRK15080 413999009561 Cell division protein FtsA; Region: FtsA; cl17206 413999009562 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 413999009563 nucleotide binding site [chemical binding]; other site 413999009564 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009565 PS00329 Heat shock hsp70 proteins family signature 2. 413999009566 Cobalamin adenosyltransferase; Region: Cob_adeno_trans; cl00920 413999009567 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882 413999009568 G1 box; other site 413999009569 GTP/Mg2+ binding site [chemical binding]; other site 413999009570 G2 box; other site 413999009571 Switch I region; other site 413999009572 G3 box; other site 413999009573 Switch II region; other site 413999009574 G4 box; other site 413999009575 G5 box; other site 413999009576 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009577 1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046 413999009578 putative hexamer interface [polypeptide binding]; other site 413999009579 putative hexagonal pore; other site 413999009580 Pfam match to entry PF06132 EutS, Ethanolamine utilisation protein EutS, score 207.6, E-value 2e-59 413999009581 glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494 413999009582 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999009583 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 83.1, E-value 5.9e-22 413999009584 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 12.7, E-value 0.0026 413999009585 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 24.8, E-value 3.2e-05 413999009586 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999009587 PS01087 Radical activating enzymes signature. 413999009588 glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774 413999009589 Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677 413999009590 dimer interface [polypeptide binding]; other site 413999009591 active site 413999009592 glycine loop; other site 413999009593 Pfam match to entry PF01228 Gly_radical, Glycine radical, score 48.7, E-value 1.4e-11 413999009594 PS00850 Glycine radical signature. 413999009595 Pfam match to entry PF02901 PFL, Pyruvate formate lyase, score 278.4, E-value 9.5e-81 413999009596 Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122 413999009597 putative catalytic cysteine [active] 413999009598 Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577 413999009599 Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045 413999009600 Hexamer interface [polypeptide binding]; other site 413999009601 Hexagonal pore residue; other site 413999009602 Pfam match to entry PF00936 Bact_microcomp,Bacterial microcompartments protein family, score 146.7,E-value 4.2e-41 413999009603 Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577 413999009604 Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045 413999009605 Hexamer interface [polypeptide binding]; other site 413999009606 Hexagonal pore residue; other site 413999009607 Pfam match to entry PF00936 Bact_microcomp,Bacterial microcompartments protein family, score 127.9,E-value 1.9e-35 413999009608 Multidrug resistance efflux transporter; Region: EmrE; pfam13536 413999009609 10 probable transmembrane helices predicted for CBO2124 by TMHMM2.0 at aa 27-49, 69-91, 112-134, 138-160,167-189, 199-221, 234-256, 271-293, 300-322 and 332-354 413999009610 Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107 413999009611 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999009612 DNA binding residues [nucleotide binding] 413999009613 drug binding residues [chemical binding]; other site 413999009614 dimer interface [polypeptide binding]; other site 413999009615 GyrI-like small molecule binding domain; Region: GyrI-like; cl01368 413999009616 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 41.4, E-value 2.1e-09 413999009617 Predicted helix-turn-helix motif with score 1211.000, SD 3.31 at aa 6-27, sequence YSIGKVGKICKITKKALRYYDK 413999009618 Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454 413999009619 1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180 413999009620 putative active site [active] 413999009621 metal binding site [ion binding]; metal-binding site 413999009622 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase, score 349.7, E-value 3.4e-102 413999009623 PS00913 Iron-containing alcohol dehydrogenases signature 1. 413999009624 PS00687 Aldehyde dehydrogenases glutamic acid active site. 413999009625 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999009626 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 413999009627 12 probable transmembrane helices predicted for CBO2127 by TMHMM2.0 at aa 12-31, 41-63, 84-106, 126-148,155-177, 181-203, 224-246, 251-273, 304-326, 351-373,380-402 and 407-426 413999009628 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009629 Pfam match to entry PF01554 MatE, MatE, score 63.1,E-value 6.2e-16 413999009630 MarR family; Region: MarR_2; pfam12802 413999009631 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999009632 Coenzyme A binding pocket [chemical binding]; other site 413999009633 Pfam match to entry PF01047 MarR, MarR family,score 31.9, E-value 1.6e-06 413999009634 Predicted helix-turn-helix motif with score 1477.000, SD 4.22 at aa 47-68, sequence TPFNELAIQLGIDKASLSRILN 413999009635 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 21.9, E-value 0.0015 413999009636 Domain of unknown function (DUF1963); Region: DUF1963; pfam09234 413999009637 Domain of unknown function (DUF4180); Region: DUF4180; pfam13788 413999009638 Helix-turn-helix domain; Region: HTH_17; pfam12728 413999009639 Predicted helix-turn-helix motif with score 1580.000, SD 4.57 at aa 6-27, sequence YTIDKIAEILGMHHKTIRKFIT 413999009640 Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_4; cd05828 413999009641 active site 413999009642 catalytic site [active] 413999009643 Pfam match to entry PF04203 Sortase, Sortase, score 155.3, E-value 1.1e-43 413999009644 1 probable transmembrane helix predicted for CBO2133 by TMHMM2.0 at aa 12-34 413999009645 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009646 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 413999009647 Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102 413999009648 active site 413999009649 Pfam match to entry PF00746 Gram_pos_anchor, Gram positive anchor, score 20.7, E-value 0.0037 413999009650 1 probable transmembrane helix predicted for CBO2134 by TMHMM2.0 at aa 862-884 413999009651 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region, score -7.3, E-value 0.089 413999009652 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999009653 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080 413999009654 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999009655 ATP binding site [chemical binding]; other site 413999009656 Mg2+ binding site [ion binding]; other site 413999009657 G-X-G motif; other site 413999009658 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 97.6,E-value 2.7e-26 413999009659 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 18.4, E-value 0.0013 413999009660 2 probable transmembrane helices predicted for CBO2135 by TMHMM2.0 at aa 12-31 and 36-58 413999009661 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999009662 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999009663 active site 413999009664 phosphorylation site [posttranslational modification] 413999009665 intermolecular recognition site; other site 413999009666 dimerization interface [polypeptide binding]; other site 413999009667 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999009668 DNA binding site [nucleotide binding] 413999009669 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 70.7, E-value 3.2e-18 413999009670 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 101.3, E-value 2e-27 413999009671 6 probable transmembrane helices predicted for CBO2137 by TMHMM2.0 at aa 13-32, 52-74, 103-125, 135-157,164-186 and 206-228 413999009672 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 413999009673 Zn binding site [ion binding]; other site 413999009674 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999009675 7 probable transmembrane helices predicted for CBO2138 by TMHMM2.0 at aa 13-35, 50-72, 97-119, 139-161,170-192, 217-239 and 252-271 413999009676 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999009677 ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264 413999009678 Walker A/P-loop; other site 413999009679 ATP binding site [chemical binding]; other site 413999009680 Q-loop/lid; other site 413999009681 ABC transporter signature motif; other site 413999009682 Walker B; other site 413999009683 D-loop; other site 413999009684 H-loop/switch region; other site 413999009685 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.9, E-value 2.6e-55 413999009686 PS00211 ABC transporters family signature. 413999009687 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009688 FtsX-like permease family; Region: FtsX; pfam02687 413999009689 10 probable transmembrane helices predicted for CBO2140 by TMHMM2.0 at aa 21-40, 55-77, 105-127, 159-181,202-219, 239-261, 290-312, 542-564, 595-617 and 637-659 413999009690 Pfam match to entry PF02687 FtsX, Predicted permease, score 38.0, E-value 2.3e-08 413999009691 putative oxidoreductase; Provisional; Region: PRK11445 413999009692 TrkA-N domain; Region: TrkA_N; pfam02254 413999009693 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 413999009694 Pfam match to entry PF01360 Monooxygenase,Monooxygenase, score 19.5, E-value 2.8e-05 413999009695 Protein of unknown function (DUF3036); Region: DUF3036; pfam11234 413999009696 4 probable transmembrane helices predicted for CBO2142 by TMHMM2.0 at aa 13-35, 50-68, 94-116 and 121-143 413999009697 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 413999009698 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cd05188 413999009699 NAD(P) binding site [chemical binding]; other site 413999009700 Pfam match to entry PF00107 ADH_zinc_N,Zinc-binding dehydrogenase, score 107.4, E-value 2.9e-29 413999009701 1 probable transmembrane helix predicted for CBO2143 by TMHMM2.0 at aa 167-184 413999009702 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 413999009703 AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060 413999009704 Metal-binding active site; metal-binding site 413999009705 Pfam match to entry PF01261 AP_endonuc_2, AP endonuclease 2, score 46.1, E-value 8.3e-11 413999009706 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose through a multistep reaction in the biosynthesis of aminoglycoside antibiotics; Region: DOIS; cd08197 413999009707 active site 413999009708 dimer interface [polypeptide binding]; other site 413999009709 metal binding site [ion binding]; metal-binding site 413999009710 Pfam match to entry PF01761 DHQ_synthase,3-dehydroquinate synthase, score 219.5, E-value 5.3e-63 413999009711 1 probable transmembrane helix predicted for CBO2145 by TMHMM2.0 at aa 112-134 413999009712 FtsX-like permease family; Region: FtsX; pfam02687 413999009713 10 probable transmembrane helices predicted for CBO2146 by TMHMM2.0 at aa 21-40, 60-82, 110-132, 164-186,207-224, 244-266, 293-315, 543-565, 594-616 and 631-653 413999009714 Pfam match to entry PF02687 FtsX, Predicted permease, score 28.2, E-value 4.3e-06 413999009715 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999009716 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999009717 Walker A/P-loop; other site 413999009718 ATP binding site [chemical binding]; other site 413999009719 Q-loop/lid; other site 413999009720 ABC transporter signature motif; other site 413999009721 Walker B; other site 413999009722 D-loop; other site 413999009723 H-loop/switch region; other site 413999009724 Pfam match to entry PF00005 ABC_tran, ABC transporter score 201.8, E-value 1.1e-57 413999009725 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009726 Transcriptional antiterminator [Transcription]; Region: BglG; COG3711 413999009727 HTH domain; Region: HTH_11; pfam08279 413999009728 HTH domain; Region: HTH_11; pfam08279 413999009729 PRD domain; Region: PRD; pfam00874 413999009730 PRD domain; Region: PRD; pfam00874 413999009731 PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568 413999009732 active site 413999009733 P-loop; other site 413999009734 phosphorylation site [posttranslational modification] 413999009735 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 413999009736 active site 413999009737 phosphorylation site [posttranslational modification] 413999009738 Pfam match to entry PF00359 PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2, score 108.3, E-value 1.5e-29 413999009739 PS00372 PTS EIIA domains phosphorylation site signature 2. 413999009740 Pfam match to entry PF00874 PRD, PRD domain, score 100.6, E-value 3.2e-27 413999009741 Pfam match to entry PF00874 PRD, PRD domain, score 70.8, E-value 3.1e-18 413999009742 Predicted helix-turn-helix motif with score 1060.000, SD 2.80 at aa 109-130, sequence VTINMLSDRMMVSRSTIINDLI 413999009743 Predicted helix-turn-helix motif with score 1716.000, SD 5.03 at aa 109-41, sequence DKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFY IIYELLNKSEFV 413999009744 Predicted helix-turn-helix motif with score 1716.000, SD 5.03 at aa 20-41, sequence ITIKEISKKVNKSPRTVRYDLD 413999009745 PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410 413999009746 11 probable transmembrane helices predicted for CBO2150 by TMHMM2.0 at aa 15-30, 37-59, 92-114, 121-143,148-167, 224-246, 256-278, 299-321, 331-353, 374-396 and 423-442 413999009747 Pfam match to entry PF04215 SgaT_UlaA, sugar-specific permease, SgaT/UlaA, score 612.9, E-value 1.9e-181 413999009748 PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563 413999009749 active site 413999009750 P-loop; other site 413999009751 phosphorylation site [posttranslational modification] 413999009752 Pfam match to entry PF02302 PTS_IIB, PTS system,Lactose/Cellobiose specific IIB subunit, score 82.8,E-value 7.5e-22 413999009753 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 413999009754 active site 413999009755 phosphorylation site [posttranslational modification] 413999009756 Pfam match to entry PF00359 PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2, score 123.6, E-value 3.8e-34 413999009757 PS00372 PTS EIIA domains phosphorylation site signature 2. 413999009758 Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956 413999009759 active site 413999009760 intersubunit interactions; other site 413999009761 catalytic residue [active] 413999009762 Pfam match to entry PF00923 Transaldolase,Transaldolase, score 88.1, E-value 1.9e-23 413999009763 3 probable transmembrane helices predicted for CBO2154 by TMHMM2.0 at aa 4-23, 71-90 and 100-122 413999009764 2 probable transmembrane helices predicted for CBO2155 by TMHMM2.0 at aa 13-35 and 62-84 413999009765 membrane protein; Provisional; Region: PRK14413 413999009766 Pfam match to entry PF02660 DUF205, Domain of unknown function DUF, score 163.2, E-value 4.7e-46 413999009767 4 probable transmembrane helices predicted for CBO2156 by TMHMM2.0 at aa 4-23, 86-105, 120-142 and 149-171 413999009768 PUA domain (predicted RNA-binding domain) [Translation, ribosomal structure and biogenesis]; Region: COG5270 413999009769 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999009770 4 probable transmembrane helices predicted for CBO2158 by TMHMM2.0 at aa 4-23, 58-80, 90-112 and 139-161 413999009771 galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527 413999009772 Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357 413999009773 active site 413999009774 substrate binding site [chemical binding]; other site 413999009775 trimer interface [polypeptide binding]; other site 413999009776 CoA binding site [chemical binding]; other site 413999009777 PS00101 Hexapeptide-repeat containing-transferases signature. 413999009778 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 17.0,E-value 0.046 413999009779 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 14.4,E-value 0.3 413999009780 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 13.8,E-value 0.44 413999009781 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999009782 POT family; Region: PTR2; cl17359 413999009783 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -113.4, E-value 0.003 413999009784 12 probable transmembrane helices predicted for CBO2162 by TMHMM2.0 at aa 15-37, 44-63, 78-100, 109-131,146-168, 189-208, 253-270, 296-318, 338-360, 367-389,404-426 and 435-457 413999009785 Pfam match to entry PF00854 PTR2, POT family, score 12.7, E-value 6.7e-10 413999009786 PS01023 PTR2 family proton/oligopeptide symporters signature 2. 413999009787 Methyltransferase domain; Region: Methyltransf_23; pfam13489 413999009788 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999009789 S-adenosylmethionine binding site [chemical binding]; other site 413999009790 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999009791 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999009792 Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871 413999009793 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 45.3, E-value 1.4e-10 413999009794 PS00041 Bacterial regulatory proteins, araC family signature. 413999009795 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 32.9, E-value 7.9e-07 413999009796 mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997 413999009797 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 413999009798 phosphate binding site [ion binding]; other site 413999009799 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999009800 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 413999009801 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 78.5, E-value 1.4e-20 413999009802 Pfam match to entry PF00724 oxidored_FMN,NADH:flavin oxidoreductase / NADH oxidase, score 243.0, E-value 4.3e-70 413999009803 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 413999009804 Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592 413999009805 DNA binding residues [nucleotide binding] 413999009806 dimer interface [polypeptide binding]; other site 413999009807 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 28.9, E-value 1.2e-05 413999009808 Predicted helix-turn-helix motif with score 1779.000, SD 5.25 at aa 3-24, sequence YSITDLAEILGYTTSAIHYFEK 413999009809 2 probable transmembrane helices predicted for CBO2168 by TMHMM2.0 at aa 3-20 and 66-88 413999009810 CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214 413999009811 Pfam match to entry PF03787 DUF324, Protein of unknown function (DUF324), score 21.8, E-value 6.3e-06 413999009812 CRISPR/Cas system-associated protein Cmr5; Region: Cmr5_III-B; cl01317 413999009813 CRISPR/Cas system-associated RAMP superfamily protein Cmr4; Region: Cmr4_III-B; cl17440 413999009814 Pfam match to entry PF03787 DUF324, Protein of unknown function (DUF324), score 73.0, E-value 6.6e-19 413999009815 CRISPR/Cas system-associated RAMP superfamily protein Cmr3; Region: Cmr3_III-B; cl12075 413999009816 CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853 413999009817 CRISPR-associated protein Cas10/Cmr2, subtype III-B; Region: cas_TM1794_Cmr2; TIGR02577 413999009818 3 probable transmembrane helices predicted for CBO2177 by TMHMM2.0 at aa 480-502, 512-531 and 543-562 413999009819 CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652 413999009820 Pfam match to entry PF01881 DUF57, Protein of unknown function DUF57, score -34.5, E-value 0.0015 413999009821 Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820 413999009822 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 413999009823 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 413999009824 Pfam match to entry PF02567 PhzC-PhzF, Phenazine biosynthesis-like protein, score 84.1, E-value 3e-22 413999009825 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 413999009826 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 413999009827 Pfam match to entry PF02567 PhzC-PhzF, Phenazine biosynthesis-like protein, score 229.3, E-value 5.9e-66 413999009828 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999009829 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999009830 DNA-binding site [nucleotide binding]; DNA binding site 413999009831 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999009832 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999009833 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999009834 homodimer interface [polypeptide binding]; other site 413999009835 catalytic residue [active] 413999009836 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 65.5, E-value 1.2e-16 413999009837 Predicted helix-turn-helix motif with score 1564.000, SD 4.51 at aa 39-60, sequence PSIRNLAKELGISPMTIIKAYN 413999009838 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 11.2, E-value 2.6e-06 413999009839 Staygreen protein; Region: Staygreen; pfam12638 413999009840 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999009841 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999009842 non-specific DNA binding site [nucleotide binding]; other site 413999009843 salt bridge; other site 413999009844 sequence-specific DNA binding site [nucleotide binding]; other site 413999009845 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 58.2, E-value 1.9e-14 413999009846 Predicted helix-turn-helix motif with score 2517.000, SD 7.76 at aa 7-28, sequence LSQEDVAEKLSVSRQTVSKWET 413999009847 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 413999009848 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 413999009849 1 probable transmembrane helix predicted for CBO2187 by TMHMM2.0 at aa 7-29 413999009850 N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228 413999009851 TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298 413999009852 active site 413999009853 putative substrate binding pocket [chemical binding]; other site 413999009854 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 250.5, E-value 2.5e-72 413999009855 xanthine permease; Region: pbuX; TIGR03173 413999009856 12 probable transmembrane helices predicted for CBO2189 by TMHMM2.0 at aa 26-48, 61-83, 103-125, 132-154,158-180, 200-222, 245-267, 279-301, 311-333, 342-364,379-396 and 408-430 413999009857 Pfam match to entry PF00860 xan_ur_permease,Permease, score 250.8, E-value 1.9e-72 413999009858 5 probable transmembrane helices predicted for CBO2190 by TMHMM2.0 at aa 13-30, 43-65, 86-104, 109-126 and 188-210 413999009859 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 413999009860 12 probable transmembrane helices predicted for CBO2191 by TMHMM2.0 at aa 7-26, 41-60, 86-108, 123-145,158-180, 195-217, 230-252, 276-298, 334-351, 366-383,395-414 and 418-437 413999009861 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score -16.8, E-value 3.3e-07 413999009862 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924 413999009863 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999009864 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 264.6, E-value 1.4e-76 413999009865 PS00455 AMP-binding domain signature. 413999009866 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 413999009867 Uncharacterized membrane protein [Function unknown]; Region: COG3949 413999009868 10 probable transmembrane helices predicted for CBO2193 by TMHMM2.0 at aa 13-32, 47-69, 90-112, 122-144,151-173, 193-215, 228-250, 272-294, 315-334 and 338-360 413999009869 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 413999009870 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 413999009871 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 413999009872 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit, score 483.3, E-value 2e-142 413999009873 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 413999009874 Ligand binding site [chemical binding]; other site 413999009875 Electron transfer flavoprotein domain; Region: ETF; pfam01012 413999009876 Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit, score 371.2, E-value 1.1e-108 413999009877 PS01065 Electron transfer flavoprotein beta-subunit signature. 413999009878 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 413999009879 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 413999009880 active site 413999009881 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain, score 293.5, E-value 2.7e-85 413999009882 PS00073 Acyl-CoA dehydrogenases signature 2. 413999009883 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain, score 151.2, E-value 1.9e-42 413999009884 PS00072 Acyl-CoA dehydrogenases signature 1. 413999009885 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain, score 135.6, E-value 9.6e-38 413999009886 benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263 413999009887 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999009888 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 312.1, E-value 7.1e-91 413999009889 benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260 413999009890 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999009891 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 473.8, E-value 1.4e-139 413999009892 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 413999009893 CoA-transferase family III; Region: CoA_transf_3; pfam02515 413999009894 Pfam match to entry PF02515 CoA_transf_3,CoA-transferase III, score 95.6, E-value 1e-25 413999009895 Flavodoxin domain; Region: Flavodoxin_5; cl17428 413999009896 4Fe-4S dicluster domain; Region: Fer4_9; pfam13187 413999009897 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 15.4, E-value 0.00095 413999009898 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999009899 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 17.7, E-value 0.00041 413999009900 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999009901 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999009902 benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260 413999009903 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 240.9, E-value 1.9e-69 413999009904 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999009905 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999009906 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 413999009907 nucleotide binding site [chemical binding]; other site 413999009908 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999009909 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score -38.5, E-value 5e-10 413999009910 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 207.0, E-value 3.1e-59 413999009911 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999009912 dimer interface [polypeptide binding]; other site 413999009913 putative CheW interface [polypeptide binding]; other site 413999009914 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score -13.7, E-value 5e-07 413999009915 Nitroreductase-like family 4. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140 413999009916 dimer interface [polypeptide binding]; other site 413999009917 FMN binding site [chemical binding]; other site 413999009918 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999009919 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 413999009920 Coenzyme A binding pocket [chemical binding]; other site 413999009921 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 50.5, E-value 3.9e-12 413999009922 Pfam match to entry PF00903 Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily, score 18.6, E-value 3.3e-05 413999009923 GntP family permease; Region: GntP_permease; pfam02447 413999009924 fructuronate transporter; Provisional; Region: PRK10034; cl15264 413999009925 12 probable transmembrane helices predicted for CBO2207 by TMHMM2.0 at aa 7-26, 30-49, 61-83, 108-130,143-162, 182-204, 245-267, 282-304, 317-339, 354-373,394-416 and 439-461 413999009926 Pfam match to entry PF02447 GntP_permease, GntP family permease, score 535.9, E-value 2.9e-158 413999009927 4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743 413999009928 Pyridoxal phosphate biosynthesis protein [Coenzyme metabolism]; Region: PdxA; COG1995 413999009929 Pfam match to entry PF04166 PdxA, Pyridoxal phosphate biosynthetic protein PdxA, score 433.2, E-value 2.4e-127 413999009930 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395 413999009931 Predicted helix-turn-helix motif with score 1049.000, SD 2.76 at aa 332-364, sequence INLDEEAKKQNTTKEFLSQIMNTSVAEISYRIM 413999009932 Predicted helix-turn-helix motif with score 1049.000, SD 2.76 at aa 343-364, sequence TTKEFLSQIMNTSVAEISYRIM 413999009933 Predicted helix-turn-helix motif with score 1007.000, SD 2.62 at aa 332-353, sequence INLDEEAKKQNTTKEFLSQIMN 413999009934 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 413999009935 helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420 413999009936 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 413999009937 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family, score 275.1, E-value 9.4e-80 413999009938 Predicted helix-turn-helix motif with score 1302.000, SD 3.62 at aa 20-41, sequence VKVEDIANELNVSLMTIRRDFD 413999009939 PS00894 Bacterial regulatory proteins, deoR family signature. 413999009940 CAAX protease self-immunity; Region: Abi; pfam02517 413999009941 6 probable transmembrane helices predicted for CBO2211 by TMHMM2.0 at aa 21-43, 58-80, 101-123, 169-188,195-212 and 264-286 413999009942 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 55.8, E-value 9.8e-14 413999009943 Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229 413999009944 Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229 413999009945 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 413999009946 1 probable transmembrane helix predicted for CBO2212 by TMHMM2.0 at aa 12-34 413999009947 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009948 Predicted helix-turn-helix motif with score 1075.000, SD 2.85 at aa 227-248, sequence ITYDIRGNKEVVNASTISNWLK 413999009949 Pfam match to entry PF03734 ErfK_YbiS_YhnG,ErfK/YbiS/YcfS/YnhG, score 26.7, E-value 1.9e-06 413999009950 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999009951 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999009952 WHG domain; Region: WHG; pfam13305 413999009953 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 48.1, E-value 2e-11 413999009954 Predicted helix-turn-helix motif with score 1985.000, SD 5.95 at aa 31-52, sequence FSLRKVAALCNVSHSAPYKHFK 413999009955 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999009956 Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053 413999009957 GxGYxY sequence motif in domain of unknown function; Region: GxGYxYP; pfam14323 413999009958 1 probable transmembrane helix predicted for CBO2216 by TMHMM2.0 at aa 7-24 413999009959 PS00383 Tyrosine specific protein phosphatases active site. 413999009960 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 413999009961 (2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233 413999009962 putative NAD(P) binding site [chemical binding]; other site 413999009963 catalytic Zn binding site [ion binding]; other site 413999009964 Pfam match to entry PF00107 ADH_zinc_N,Zinc-binding dehydrogenase, score 328.7, E-value 6.7e-96 413999009965 PS00059 Zinc-containing alcohol dehydrogenases signature. 413999009966 carbon-monoxide dehydrogenase, catalytic subunit; Region: CO_DH_cata; TIGR01702 413999009967 Carbon monoxide dehydrogenase (CODH) is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA, respectively. CODH has two types of metal clusters, a cubane [Fe4-S4] center (B-cluster) similar to...; Region: CODH; cd01915 413999009968 ACS interaction site; other site 413999009969 CODH interaction site; other site 413999009970 cubane metal cluster (B-cluster) [ion binding]; other site 413999009971 Ni-Fe-S cluster (C-cluster) [ion binding]; other site 413999009972 Pfam match to entry PF03063 Prismane, Prismane/CO dehydrogenase, score 748.3, E-value 3.3e-222 413999009973 PS00267 Tachykinin family signature. 413999009974 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375 413999009975 Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155 413999009976 Transmembrane protein 55A; Region: Tmemb_55A; pfam09788 413999009977 Pfam match to entry PF01155 HypA, Hydrogenase expression/synthesis hypA family, score 102.3, E-value 1e-27 413999009978 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999009979 Pfam match to entry PF01495 HypB_UreG, HypB/UreG nucleotide-binding domain, score 182.0, E-value 1e-51 413999009980 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009981 This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851 413999009982 Pfam match to entry PF02579 Nitro_FeMo-Co,Dinitrogenase iron-molybdenum cofactor, score 64.4,E-value 2.5e-16 413999009983 This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110 413999009984 P loop nucleotide binding; other site 413999009985 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149 413999009986 switch II; other site 413999009987 Pfam match to entry PF00991 ParA, ParA family ATPase, score 45.1, E-value 1.6e-10 413999009988 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 34.1, E-value 3.3e-07 413999009989 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999009990 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 28.6, E-value 7.8e-06 413999009991 PS00017 ATP/GTP-binding site motif A (P-loop). 413999009992 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149 413999009993 This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110 413999009994 P loop nucleotide binding; other site 413999009995 switch II; other site 413999009996 Pfam match to entry PF00991 ParA, ParA family ATPase, score 48.9, E-value 1.2e-11 413999009997 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 27.2, E-value 1.3e-05 413999009998 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 33.7, E-value 4.5e-07 413999009999 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010000 This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851 413999010001 Pfam match to entry PF02579 Nitro_FeMo-Co,Dinitrogenase iron-molybdenum cofactor, score 55.2,E-value 1.5e-13 413999010002 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010003 flagellar motor protein MotB; Reviewed; Region: motB; PRK07734 413999010004 Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677 413999010005 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 413999010006 ligand binding site [chemical binding]; other site 413999010007 Pfam match to entry PF00691 OmpA, OmpA family,score 113.5, E-value 4.3e-31 413999010008 1 probable transmembrane helix predicted for CBO2226 by TMHMM2.0 at aa 15-37 413999010009 flagellar motor protein MotA; Validated; Region: PRK08124 413999010010 MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568 413999010011 Pfam match to entry PF01618 MotA_ExbB,MotA/TolQ/ExbB proton channel family, score 76.9, E-value 4.5e-20 413999010012 PS01307 Flagellar motor protein motA family signature. 413999010013 4 probable transmembrane helices predicted for CBO2227 by TMHMM2.0 at aa 3-22, 27-49, 142-164 and 179-201 413999010014 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999010015 Putative cell wall-binding domain [Cell envelope biogenesis, outer membrane]; Region: LytB; COG2247 413999010016 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999010017 Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122 413999010018 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 86.6, E-value 5.4e-23 413999010019 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 66.9, E-value 4.5e-17 413999010020 Pfam match to entry PF04122 CW_binding_2, cell wall binding repeat 2, score 40.6, E-value 3.8e-09 413999010021 Domain of unknown function (DUF4352); Region: DUF4352; pfam11611 413999010022 1 probable transmembrane helix predicted for CBO2229 by TMHMM2.0 at aa 13-35 413999010023 OPT oligopeptide transporter protein; Region: OPT; cl14607 413999010024 putative oligopeptide transporter, OPT family; Region: TIGR00733 413999010025 16 probable transmembrane helices predicted for CBO2231 by TMHMM2.0 at aa 34-56, 60-82, 95-117, 122-144,222-241, 246-268, 281-303, 331-353, 360-382, 392-414,421-440, 455-474, 508-530, 535-557, 577-599 and 609-631 413999010026 Pfam match to entry PF03169 OPT, OPT oligopeptide transporter protein, score 150.7, E-value 2.6e-42 413999010027 Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893 413999010028 M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890 413999010029 metal binding site [ion binding]; metal-binding site 413999010030 dimer interface [polypeptide binding]; other site 413999010031 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 134.6, E-value 1.9e-37 413999010032 Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008 413999010033 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 413999010034 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999010035 catalytic residue [active] 413999010036 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 413999010037 Pfam match to entry PF02595 Gly_kinase, Glycerate kinase, score 644.2, E-value 7.5e-191 413999010038 oxidoreductase; Provisional; Region: PRK08017 413999010039 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999010040 NAD(P) binding site [chemical binding]; other site 413999010041 active site 413999010042 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 125.0, E-value 1.4e-34 413999010043 ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668 413999010044 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 413999010045 ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679 413999010046 6 probable transmembrane helices predicted for CBO2238 by TMHMM2.0 at aa 23-42, 182-204, 232-254,274-296, 309-326 and 361-383 413999010047 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999010048 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999010049 Walker A/P-loop; other site 413999010050 ATP binding site [chemical binding]; other site 413999010051 Q-loop/lid; other site 413999010052 ABC transporter signature motif; other site 413999010053 Walker B; other site 413999010054 D-loop; other site 413999010055 H-loop/switch region; other site 413999010056 Pfam match to entry PF00005 ABC_tran, ABC transporter score 200.3, E-value 3.2e-57 413999010057 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010058 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999010059 Coenzyme A binding pocket [chemical binding]; other site 413999010060 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 49.2, E-value 9.9e-12 413999010061 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999010062 MarR family; Region: MarR_2; pfam12802 413999010063 Pfam match to entry PF01047 MarR, MarR family,score 50.7, E-value 3.3e-12 413999010064 Predicted helix-turn-helix motif with score 1162.000, SD 3.14 at aa 35-56, sequence MFLVRICENPGINQETLSNMLK 413999010065 Protein of unknown function (DUF2809); Region: DUF2809; pfam10990 413999010066 4 probable transmembrane helices predicted for CBO2242 by TMHMM2.0 at aa 7-24, 34-56, 63-82 and 108-127 413999010067 methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252 413999010068 The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465 413999010069 Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D), score -31.6, E-value 2.3e-09 413999010070 Predicted dehydrogenase [General function prediction only]; Region: COG0579 413999010071 hydroxyglutarate oxidase; Provisional; Region: PRK11728 413999010072 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 413999010073 Pfam match to entry PF04324 fer2_BFD, BFD-like [2Fe-2S] binding domain, score 82.8, E-value 7.6e-22 413999010074 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase, score 2.3, E-value 1.6e-07 413999010075 Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107 413999010076 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 413999010077 DNA binding residues [nucleotide binding] 413999010078 drug binding residues [chemical binding]; other site 413999010079 dimer interface [polypeptide binding]; other site 413999010080 Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871 413999010081 Pfam match to entry PF00376 merR, MerR family regulatory protein, score 38.5, E-value 1.6e-08 413999010082 Amino acid permease; Region: AA_permease_2; pfam13520 413999010083 11 probable transmembrane helices predicted for CBO2246 by TMHMM2.0 at aa 10-32, 37-59, 129-146, 158-180,195-217, 238-260, 287-309, 346-365, 375-394, 413-435 and 445-462 413999010084 Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908 413999010085 putative ADP-ribose binding site [chemical binding]; other site 413999010086 putative active site [active] 413999010087 Pfam match to entry PF01661 A1pp, Appr-1-p processing enzyme family, score 181.9, E-value 1.1e-51 413999010088 Protein of unknown function (DUF1294); Region: DUF1294; cl01311 413999010089 2 probable transmembrane helices predicted for CBO2248 by TMHMM2.0 at aa 34-51 and 66-83 413999010090 MarR family; Region: MarR_2; cl17246 413999010091 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999010092 Pfam match to entry PF01047 MarR, MarR family,score 92.2, E-value 1.1e-24 413999010093 TIGR03987 family protein; Region: TIGR03987 413999010094 4 probable transmembrane helices predicted for CBO2251 by TMHMM2.0 at aa 5-24, 37-54, 74-96 and 109-129 413999010095 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010096 4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170 413999010097 substrate binding site [chemical binding]; other site 413999010098 multimerization interface [polypeptide binding]; other site 413999010099 ATP binding site [chemical binding]; other site 413999010100 Pfam match to entry PF02110 HK,Hydroxyethylthiazole kinase, score 194.7, E-value 1.5e-55 413999010101 Thiamine-precursor transporter protein (ThiW); Region: ThiW; pfam09512 413999010102 6 probable transmembrane helices predicted for CBO2254 by TMHMM2.0 at aa 12-31, 41-58, 70-92, 96-118,125-147 and 162-184 413999010103 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 413999010104 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999010105 Coenzyme A binding pocket [chemical binding]; other site 413999010106 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 67.4, E-value 3.2e-17 413999010107 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999010108 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 105.9, E-value 8.4e-29 413999010109 Mor transcription activator family; Region: Mor; cl02360 413999010110 Predicted helix-turn-helix motif with score 1849.000, SD 5.48 at aa 84-105, sequence ISIKKLAQQYYLTEHSIRRIIR 413999010111 AAA domain; Region: AAA_26; pfam13500 413999010112 dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090 413999010113 biotin synthase; Region: bioB; TIGR00433 413999010114 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999010115 FeS/SAM binding site; other site 413999010116 Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968 413999010117 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 76.3, E-value 6.5e-20 413999010118 Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268 413999010119 Pfam match to entry PF02632 BioY, BioY family,score 68.9, E-value 1.1e-17 413999010120 6 probable transmembrane helices predicted for CBO2260 by TMHMM2.0 at aa 12-29, 34-51, 58-80, 84-103,110-132 and 147-169 413999010121 hypothetical protein; Provisional; Region: PRK09272 413999010122 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999010123 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 413999010124 putative DNA binding site [nucleotide binding]; other site 413999010125 putative Zn2+ binding site [ion binding]; other site 413999010126 Pfam match to entry PF01047 MarR, MarR family,score 69.1, E-value 9.8e-18 413999010127 Predicted helix-turn-helix motif with score 1390.000, SD 3.92 at aa 47-68, sequence TTIGDLAKHINTSSNTASEHIK 413999010128 Domain of Unknown Function with PDB structure (DUF3862); Region: DUF3862; pfam12978 413999010129 1 probable transmembrane helix predicted for CBO2262 by TMHMM2.0 at aa 13-30 413999010130 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 413999010131 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 413999010132 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 413999010133 A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279 413999010134 active site 413999010135 Pfam match to entry PF00557 Peptidase_M24,metallopeptidase M24, score 45.2, E-value 1.2e-10 413999010136 amino acid/peptide transporter (Peptide:H+ symporter), bacterial; Region: yjdL_sub1_fam; TIGR00924 413999010137 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999010138 putative substrate translocation pore; other site 413999010139 12 probable transmembrane helices predicted for CBO2264 by TMHMM2.0 at aa 12-34, 54-73, 85-102, 112-134,147-169, 189-208, 255-277, 292-314, 334-353, 363-385,398-417 and 427-449 413999010140 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -89.5, E-value 0.00052 413999010141 Pfam match to entry PF00854 PTR2, POT family, score 22.4, E-value 2.1e-10 413999010142 PS01023 PTR2 family proton/oligopeptide symporters signature 2. 413999010143 Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659 413999010144 YmaF family; Region: YmaF; pfam12788 413999010145 Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which...; Region: Ntn_CGH_like; cd01935 413999010146 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417 413999010147 active site 413999010148 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999010149 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 413999010150 YmaF family; Region: YmaF; pfam12788 413999010151 hypothetical protein; Provisional; Region: PRK05802 413999010152 FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192 413999010153 FAD binding pocket [chemical binding]; other site 413999010154 FAD binding motif [chemical binding]; other site 413999010155 phosphate binding motif [ion binding]; other site 413999010156 beta-alpha-beta structure motif; other site 413999010157 NAD binding pocket [chemical binding]; other site 413999010158 Iron coordination center [ion binding]; other site 413999010159 PS00200 Rieske iron-sulfur protein signature 2. 413999010160 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 413999010161 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999010162 methionine sulfoxide reductase B; Provisional; Region: PRK00222 413999010163 SelR domain; Region: SelR; pfam01641 413999010164 Pfam match to entry PF01641 SelR, SelR domain,score 288.5, E-value 8.8e-84 413999010165 Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605 413999010166 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 413999010167 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 413999010168 Pfam match to entry PF02777 sodfe_C, Iron/manganese superoxide dismutases, C-terminal domain, score 184.7,E-value 1.5e-52 413999010169 PS00088 Manganese and iron superoxide dismutases signature. 413999010170 Pfam match to entry PF00081 sodfe, Iron/manganese superoxide dismutases, alpha-hairpin domain, score 139.3,E-value 7.2e-39 413999010171 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999010172 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999010173 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999010174 Walker A/P-loop; other site 413999010175 ATP binding site [chemical binding]; other site 413999010176 Q-loop/lid; other site 413999010177 ABC transporter signature motif; other site 413999010178 Walker B; other site 413999010179 D-loop; other site 413999010180 H-loop/switch region; other site 413999010181 Pfam match to entry PF00005 ABC_tran, ABC transporter score 210.1, E-value 3.4e-60 413999010182 PS00211 ABC transporters family signature. 413999010183 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010184 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score -12.6, E-value 0.0046 413999010185 5 probable transmembrane helices predicted for CBO2278 by TMHMM2.0 at aa 20-42, 57-79, 143-160, 164-183 and 254-276 413999010186 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999010187 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 413999010188 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999010189 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999010190 Walker A/P-loop; other site 413999010191 ATP binding site [chemical binding]; other site 413999010192 Q-loop/lid; other site 413999010193 ABC transporter signature motif; other site 413999010194 Walker B; other site 413999010195 D-loop; other site 413999010196 H-loop/switch region; other site 413999010197 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.4, E-value 3.6e-55 413999010198 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010199 PS00211 ABC transporters family signature. 413999010200 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010201 6 probable transmembrane helices predicted for CBO2279 by TMHMM2.0 at aa 21-43, 58-80, 141-158, 162-181,247-269 and 279-301 413999010202 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region, score 62.0, E-value 1.3e-15 413999010203 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999010204 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999010205 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 40.2, E-value 4.8e-09 413999010206 PS00041 Bacterial regulatory proteins, araC family signature. 413999010207 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 2.6, E-value 1.5 413999010208 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999010209 6 probable transmembrane helices predicted for CBO2281 by TMHMM2.0 at aa 12-34, 49-71, 92-114, 136-158,163-182 and 215-237 413999010210 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999010211 6 probable transmembrane helices predicted for CBO2282 by TMHMM2.0 at aa 17-34, 54-73, 103-125, 140-162,167-184 and 224-242 413999010212 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999010213 ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268 413999010214 Walker A/P-loop; other site 413999010215 ATP binding site [chemical binding]; other site 413999010216 Q-loop/lid; other site 413999010217 ABC transporter signature motif; other site 413999010218 Walker B; other site 413999010219 D-loop; other site 413999010220 H-loop/switch region; other site 413999010221 Pfam match to entry PF00005 ABC_tran, ABC transporter score 193.9, E-value 2.6e-55 413999010222 PS00211 ABC transporters family signature. 413999010223 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010224 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999010225 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999010226 dimer interface [polypeptide binding]; other site 413999010227 phosphorylation site [posttranslational modification] 413999010228 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999010229 ATP binding site [chemical binding]; other site 413999010230 Mg2+ binding site [ion binding]; other site 413999010231 G-X-G motif; other site 413999010232 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 121.3, E-value 1.9e-33 413999010233 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 61.6, E-value 1.8e-15 413999010234 1 probable transmembrane helix predicted for CBO2284 by TMHMM2.0 at aa 4-21 413999010235 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999010236 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999010237 active site 413999010238 phosphorylation site [posttranslational modification] 413999010239 intermolecular recognition site; other site 413999010240 dimerization interface [polypeptide binding]; other site 413999010241 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999010242 DNA binding site [nucleotide binding] 413999010243 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 104.9, E-value 1.6e-28 413999010244 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 131.0, E-value 2.2e-36 413999010245 DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133 413999010246 active site 413999010247 catalytic site [active] 413999010248 substrate binding site [chemical binding]; other site 413999010249 Pfam match to entry PF00929 Exonuclease,Exonuclease, score 34.5, E-value 6e-08 413999010250 Stress responsive A/B Barrel Domain; Region: Dabb; smart00886 413999010251 Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237 413999010252 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 28.9, E-value 1.5e-07 413999010253 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 413999010254 active site 413999010255 catalytic residues [active] 413999010256 metal binding site [ion binding]; metal-binding site 413999010257 Pfam match to entry PF01327 Pep_deformylase,Polypeptide deformylase, score 196.7, E-value 3.8e-56 413999010258 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999010259 non-specific DNA binding site [nucleotide binding]; other site 413999010260 salt bridge; other site 413999010261 sequence-specific DNA binding site [nucleotide binding]; other site 413999010262 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 54.8, E-value 1.9e-13 413999010263 Predicted helix-turn-helix motif with score 1832.000, SD 5.43 at aa 15-36, sequence LTQEQLGELVGVSRQAINAIET 413999010264 transglutaminase; Provisional; Region: tgl; PRK03187 413999010265 short chain dehydrogenase; Provisional; Region: PRK06701 413999010266 classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355 413999010267 NAD binding site [chemical binding]; other site 413999010268 metal binding site [ion binding]; metal-binding site 413999010269 active site 413999010270 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 265.0, E-value 1e-76 413999010271 PS00061 Short-chain dehydrogenases/reductases family signature. 413999010272 Domain of Unknown Function with PDB structure (DUF3862); Region: DUF3862; pfam12978 413999010273 1 probable transmembrane helix predicted for CBO2294 by TMHMM2.0 at aa 13-32 413999010274 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364 413999010275 9 probable transmembrane helices predicted for CBO2295 by TMHMM2.0 at aa 13-30, 87-109, 118-135, 139-161,168-190, 205-224, 355-377, 392-414 and 421-440 413999010276 Pfam match to entry PF02366 PMT,Dolichyl-phosphate-mannose-protein mannosyltransferase,score -5.3, E-value 0.0031 413999010277 PS00636 Nt-dnaJ domain signature. 413999010278 3 probable transmembrane helices predicted for CBO2296 by TMHMM2.0 at aa 7-29, 34-56 and 69-91 413999010279 4 probable transmembrane helices predicted for CBO2297 by TMHMM2.0 at aa 7-29, 39-61, 105-127 and 142-164 413999010280 1 probable transmembrane helix predicted for CBO2298 by TMHMM2.0 at aa 84-106 413999010281 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 413999010282 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999010283 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 79.7, E-value 6.2e-21 413999010284 PS01063 Sigma-70 factors ECF subfamily signature. 413999010285 Spore germination protein; Region: Spore_permease; pfam03845 413999010286 10 probable transmembrane helices predicted for CBO2300 by TMHMM2.0 at aa 13-32, 42-64, 85-107, 117-138,145-167, 189-211, 218-240, 260-282, 303-320 and 335-357 413999010287 Pfam match to entry PF03845 Spore_permease, Spore germination protein, score 360.7, E-value 1.6e-105 413999010288 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 413999010289 tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299 413999010290 active site 413999010291 NTP binding site [chemical binding]; other site 413999010292 metal binding triad [ion binding]; metal-binding site 413999010293 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 413999010294 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999010295 Zn2+ binding site [ion binding]; other site 413999010296 Mg2+ binding site [ion binding]; other site 413999010297 tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735 413999010298 Pfam match to entry PF01966 HD, HD domain, score 39.3, E-value 9.4e-09 413999010299 Pfam match to entry PF01743 PolyA_pol, Poly A polymerase, score 188.3, E-value 1.3e-53 413999010300 Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417 413999010301 Src Homology 3 domain superfamily; Region: SH3; cl17036 413999010302 Predicted transcriptional regulators [Transcription]; Region: COG1695 413999010303 Transcriptional regulator PadR-like family; Region: PadR; cl17335 413999010304 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family, score 83.8, E-value 3.6e-22 413999010305 Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030 413999010306 3 probable transmembrane helices predicted for CBO2305 by TMHMM2.0 at aa 76-98, 111-129 and 165-187 413999010307 PS00012 Phosphopantetheine attachment site. 413999010308 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999010309 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999010310 dimer interface [polypeptide binding]; other site 413999010311 phosphorylation site [posttranslational modification] 413999010312 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999010313 ATP binding site [chemical binding]; other site 413999010314 Mg2+ binding site [ion binding]; other site 413999010315 G-X-G motif; other site 413999010316 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 120.0, E-value 4.7e-33 413999010317 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010318 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 80.6, E-value 3.3e-21 413999010319 Pfam match to entry PF00672 HAMP, HAMP domain,score 17.4, E-value 0.036 413999010320 2 probable transmembrane helices predicted for CBO2306 by TMHMM2.0 at aa 21-43 and 94-116 413999010321 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999010322 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999010323 active site 413999010324 phosphorylation site [posttranslational modification] 413999010325 intermolecular recognition site; other site 413999010326 dimerization interface [polypeptide binding]; other site 413999010327 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999010328 DNA binding site [nucleotide binding] 413999010329 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 54.4, E-value 2.7e-13 413999010330 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 139.2, E-value 7.5e-39 413999010331 PS00217 Sugar transport proteins signature 2. 413999010332 Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153 413999010333 1 probable transmembrane helix predicted for CBO2308 by TMHMM2.0 at aa 112-134 413999010334 Pfam match to entry PF00627 UBA, UBA/TS-N domain,score 25.8, E-value 0.00011 413999010335 1 probable transmembrane helix predicted for CBO2309 by TMHMM2.0 at aa 114-136 413999010336 Pfam match to entry PF00627 UBA, UBA/TS-N domain,score 24.9, E-value 0.0002 413999010337 hypothetical protein; Provisional; Region: PRK06921 413999010338 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999010339 Walker A motif; other site 413999010340 ATP binding site [chemical binding]; other site 413999010341 Walker B motif; other site 413999010342 arginine finger; other site 413999010343 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010344 Pfam match to entry PF01134 GIDA, Glucose inhibited division protein A, score 71.1, E-value 1.9e-19 413999010345 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999010346 prophage 413999010347 Predicted helix-turn-helix motif with score 1592.000, SD 4.61 at aa 1-22, sequence MTSKELGEKIGITSAGIINYEN 413999010348 Predicted helix-turn-helix motif with score 1592.000, SD 4.61 at aa 69-90, sequence LTQKEAAIFLQIAERTYYSWEK 413999010349 Domain of unknown function (DUF4359); Region: DUF4359; pfam14271 413999010350 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999010351 AAA-like domain; Region: AAA_10; pfam12846 413999010352 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010353 1 probable transmembrane helix predicted for CBO2315 by TMHMM2.0 at aa 29-51 413999010354 2 probable transmembrane helices predicted for CBO2316 by TMHMM2.0 at aa 76-95 and 105-127 413999010356 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999010357 non-specific DNA binding site [nucleotide binding]; other site 413999010358 salt bridge; other site 413999010359 sequence-specific DNA binding site [nucleotide binding]; other site 413999010360 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 50.2, E-value 4.9e-12 413999010361 Predicted helix-turn-helix motif with score 1684.000, SD 4.92 at aa 16-37, sequence MDQKQFYTMLGISKSTYSQIEN 413999010362 Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847 413999010363 active site 413999010364 catalytic triad [active] 413999010365 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999010366 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 413999010367 Walker A motif; other site 413999010368 ATP binding site [chemical binding]; other site 413999010369 Walker B motif; other site 413999010370 arginine finger; other site 413999010371 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 146.3, E-value 5.8e-41 413999010372 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010373 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999010374 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999010375 active site 413999010376 metal binding site [ion binding]; metal-binding site 413999010377 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999010378 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 70.1, E-value 4.9e-18 413999010379 Haemolysin XhlA; Region: XhlA; pfam10779 413999010380 1 probable transmembrane helix predicted for CBO2327 by TMHMM2.0 at aa 61-83 413999010381 Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315 413999010382 C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145 413999010383 cofactor binding site; other site 413999010384 DNA binding site [nucleotide binding] 413999010385 substrate interaction site [chemical binding]; other site 413999010386 Pfam match to entry PF00145 DNA_methylase, C-5 cytosine-specific DNA methylase, score 251.6, E-value 1.1e-72 413999010387 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 413999010388 PS00094 C-5 cytosine-specific DNA methylases active site. 413999010389 Phage uncharacterized protein (Phage_XkdX); Region: Phage_XkdX; cl09900 413999010390 Phage tail-collar fibre protein; Region: DUF3751; pfam12571 413999010391 PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493 413999010392 Trp docking motif [polypeptide binding]; other site 413999010393 active site 413999010394 PQQ-like domain; Region: PQQ_2; pfam13360 413999010395 Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076 413999010396 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817 413999010397 Baseplate J-like protein; Region: Baseplate_J; pfam04865 413999010398 Protein of unknown function (DUF2634); Region: DUF2634; pfam10934 413999010399 Predicted helix-turn-helix motif with score 978.000, SD 2.52 at aa 130-151, sequence NTRTKLAKAVYRSESILGMMLK 413999010400 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 413999010401 Pfam match to entry PF01476 LysM, LysM domain,score 1.2, E-value 15 413999010402 Pfam match to entry PF01476 LysM, LysM domain,score 21.7, E-value 2.1e-05 413999010403 1 probable transmembrane helix predicted for CBO2338 by TMHMM2.0 at aa 5-24 413999010404 phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760 413999010405 1 probable transmembrane helix predicted for CBO2339 by TMHMM2.0 at aa 77-99 413999010406 Phage XkdN-like protein; Region: XkdN; pfam08890 413999010407 Protein of unknown function (DUF2001); Region: DUF2001; pfam09393 413999010408 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999010409 Phage tail sheath protein; Region: Phage_sheath_1; pfam04984 413999010410 Phage major capsid protein E; Region: Phage_cap_E; pfam03864 413999010411 Pfam match to entry PF03864 Phage_cap_E, Phage major capsid protein E, score -92.8, E-value 5.8e-06 413999010412 Phage minor structural protein GP20; Region: Phage_GP20; pfam06810 413999010413 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 413999010414 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999010415 Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133 413999010416 Phage terminase large subunit; Region: Terminase_3; cl12054 413999010417 Terminase-like family; Region: Terminase_6; pfam03237 413999010418 Pfam match to entry PF04466 Terminase_3, Phage terminase large subunit, score 253.9, E-value 2.3e-73 413999010419 Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056 413999010420 Terminase small subunit; Region: Terminase_2; pfam03592 413999010421 Pfam match to entry PF03592 Terminase_2, Terminase small subunit, score 112.2, E-value 1e-30 413999010422 Predicted helix-turn-helix motif with score 1731.000, SD 5.08 at aa 21-42, sequence MKYKDIASKYNVSINTVKSWKQ 413999010423 3 probable transmembrane helices predicted for CBO2357 by TMHMM2.0 at aa 10-32, 45-64 and 69-91 413999010424 YopX protein; Region: YopX; pfam09643 413999010425 PS00228 Tubulin-beta mRNA autoregulation signal. 413999010426 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236 413999010427 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 413999010428 active site 413999010429 DNA binding site [nucleotide binding] 413999010430 Int/Topo IB signature motif; other site 413999010431 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score 102.9, E-value 6.7e-28 413999010432 Predicted helix-turn-helix motif with score 1111.000, SD 2.97 at aa 262-283, sequence REIKKIASRAGINKSIYPHLFR 413999010433 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain, score 26.1, E-value 8.9e-05 413999010434 Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467 413999010435 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230 413999010436 Protein of unknown function (DUF1064); Region: DUF1064; pfam06356 413999010437 Pfam match to entry PF06356 DUF1064, Protein of unknown function (DUF1064), score 167.2, E-value 2.8e-47 413999010438 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010439 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u5; cd11542 413999010440 metal binding site [ion binding]; metal-binding site 413999010441 Pfam match to entry PF03819 MazG, MazG nucleotide pyrophosphohydrolase domain, score 35.8, E-value 1e-07 413999010442 SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966 413999010443 Pfam match to entry PF04014 SpoVT_AbrB, SpoVT / AbrB like domain, score 54.0, E-value 3.5e-13 413999010444 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999010445 RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980 413999010446 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999010447 DNA binding residues [nucleotide binding] 413999010448 Predicted helix-turn-helix motif with score 1965.000, SD 5.88 at aa 146-167, sequence KTQKQIGEEIGLKQSYISRILK 413999010449 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 12.9, E-value 0.0076 413999010450 hypothetical protein; Validated; Region: PRK08116 413999010451 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999010452 Walker A motif; other site 413999010453 ATP binding site [chemical binding]; other site 413999010454 Walker B motif; other site 413999010455 arginine finger; other site 413999010456 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010457 N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; pfam09681 413999010458 1 probable transmembrane helix predicted for CBO2380 by TMHMM2.0 at aa 40-62 413999010460 Siphovirus Gp157; Region: Sipho_Gp157; pfam05565 413999010461 Pfam match to entry PF05565 Sipho_Gp157, Siphovirus Gp157, score 178.2, E-value 1.4e-50 413999010462 Class I aldolases; Region: Aldolase_Class_I; cl17187 413999010463 Prophage antirepressor [Transcription]; Region: COG3617 413999010464 BRO family, N-terminal domain; Region: Bro-N; smart01040 413999010465 Pfam match to entry PF02498 Bro-N, BRO family,N-terminal domain, score 96.8, E-value 4.6e-26 413999010466 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999010467 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999010468 non-specific DNA binding site [nucleotide binding]; other site 413999010469 salt bridge; other site 413999010470 sequence-specific DNA binding site [nucleotide binding]; other site 413999010471 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 46.8, E-value 5.2e-11 413999010472 Predicted helix-turn-helix motif with score 1279.000, SD 3.54 at aa 15-36, sequence DTQKDLADFLGVRVSTFNFKEN 413999010473 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999010474 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999010475 non-specific DNA binding site [nucleotide binding]; other site 413999010476 salt bridge; other site 413999010477 sequence-specific DNA binding site [nucleotide binding]; other site 413999010478 Predicted helix-turn-helix motif with score 1974.000, SD 5.91 at aa 6-27, sequence ERIKELREEKGINQLELSKILN 413999010479 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 70.5, E-value 3.6e-18 413999010480 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999010481 non-specific DNA binding site [nucleotide binding]; other site 413999010482 salt bridge; other site 413999010483 sequence-specific DNA binding site [nucleotide binding]; other site 413999010484 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 50.6, E-value 3.6e-12 413999010485 Predicted helix-turn-helix motif with score 1991.000, SD 5.97 at aa 16-37, sequence ISQNKLAKKINISQSYLSSVER 413999010486 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 413999010487 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 413999010488 catalytic residues [active] 413999010489 catalytic nucleophile [active] 413999010490 Presynaptic Site I dimer interface [polypeptide binding]; other site 413999010491 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 413999010492 Synaptic Flat tetramer interface [polypeptide binding]; other site 413999010493 Synaptic Site I dimer interface [polypeptide binding]; other site 413999010494 DNA binding site [nucleotide binding] 413999010495 Recombinase; Region: Recombinase; pfam07508 413999010496 Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408 413999010497 Pfam match to entry PF00239 resolvase, Resolvase, N terminal domain, score 93.6, E-value 4e-25 413999010498 Pfam match to entry PF01134 GIDA, Glucose inhibited division protein A, score 113.0, E-value 6e-31 413999010499 Adenylsuccinate lyase (ASL)_subgroup 2; Region: Adenylsuccinate_lyase_2; cd03302 413999010500 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015 413999010501 tetramer interface [polypeptide binding]; other site 413999010502 active site 413999010503 Pfam match to entry PF00206 lyase_1, Lyase, score 175.2, E-value 1.1e-49 413999010504 PS00163 Fumarate lyases signature. 413999010505 Uncharacterized conserved protein [Function unknown]; Region: COG2155 413999010506 Pfam match to entry PF04070 DUF378, Domain of unknown function (DUF378), score 41.1, E-value 2.6e-09 413999010507 2 probable transmembrane helices predicted for CBO2397 by TMHMM2.0 at aa 13-35 and 45-67 413999010508 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 413999010509 dimerization domain swap beta strand [polypeptide binding]; other site 413999010510 regulatory protein interface [polypeptide binding]; other site 413999010511 active site 413999010512 regulatory phosphorylation site [posttranslational modification]; other site 413999010513 Pfam match to entry PF00381 PTS-HPr, PTS HPr component phosphorylation site, score 111.0, E-value 2.4e-30 413999010514 PS00589 PTS HPR component serine phosphorylation site signature. 413999010515 PS00369 PTS HPR component histidine phosphorylation site signature. 413999010516 aspartate aminotransferase; Provisional; Region: PRK05764 413999010517 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999010518 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999010519 homodimer interface [polypeptide binding]; other site 413999010520 catalytic residue [active] 413999010521 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 231.7, E-value 1.1e-66 413999010522 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 413999010523 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971 413999010524 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6, score 44.5, E-value 4.8e-11 413999010525 4 probable transmembrane helices predicted for CBO2400 by TMHMM2.0 at aa 2-24, 39-61, 74-93 and 97-116 413999010526 9 probable transmembrane helices predicted for CBO2401 by TMHMM2.0 at aa 21-40, 69-91, 93-110, 134-156,169-191, 206-223, 343-365, 375-392 and 399-421 413999010527 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324 413999010528 7 probable transmembrane helices predicted for CBO2402 by TMHMM2.0 at aa 15-37, 44-61, 87-106, 113-144,159-176, 232-249 and 269-286 413999010529 Pfam match to entry PF01040 UbiA, UbiA prenyltransferase, score 18.2, E-value 1.2e-05 413999010530 Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232 413999010531 Pfam match to entry PF04232 SpoVS, Stage V sporulation protein S (SpoVS), score 223.3, E-value 3.8e-64 413999010532 Domain of unknown function (DUF3552); Region: DUF3552; pfam12072 413999010533 Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418 413999010534 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999010535 Zn2+ binding site [ion binding]; other site 413999010536 Mg2+ binding site [ion binding]; other site 413999010537 Pfam match to entry PF01966 HD, HD domain, score 91.7, E-value 1.6e-24 413999010538 Pfam match to entry PF00013 KH, KH domain, score 29.1, E-value 1e-05 413999010539 1 probable transmembrane helix predicted for CBO2404 by TMHMM2.0 at aa 7-25 413999010540 recombinase A; Provisional; Region: recA; PRK09354 413999010541 RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983 413999010542 hexamer interface [polypeptide binding]; other site 413999010543 Walker A motif; other site 413999010544 ATP binding site [chemical binding]; other site 413999010545 Walker B motif; other site 413999010546 Pfam match to entry PF00154 recA, recA bacterial DNA recombination protein, score 795.4, E-value 2.3e-236 413999010547 PS00321 recA signature. 413999010548 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010549 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453 413999010550 Pfam match to entry PF01066 CDP-OH_P_transf,CDP-alcohol phosphatidyltransferase, score 123.1, E-value 5.5e-34 413999010551 4 probable transmembrane helices predicted for CBO2406 by TMHMM2.0 at aa 21-43, 77-99, 129-151 and 161-183 413999010552 PS00379 CDP-alcohol phosphatidyltransferases signature. 413999010553 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621 413999010554 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 413999010555 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 110.3, E-value 4e-30 413999010556 PS01278 Uncharacterized protein family UPF0004 signature. 413999010557 Pfam match to entry PF00919 UPF0004,Uncharacterized protein family UPF0004, score 121.8,E-value 1.3e-33 413999010558 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 413999010559 Tetraspanin family; Region: Tetraspannin; pfam00335 413999010560 DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674 413999010561 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 413999010562 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 413999010563 Pfam match to entry PF01580 FtsK_SpoIIIE,FtsK/SpoIIIE family, score 281.4, E-value 1.2e-81 413999010564 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010565 5 probable transmembrane helices predicted for CBO2408 by TMHMM2.0 at aa 20-42, 52-74, 86-105, 125-144 and 151-173 413999010566 signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706 413999010567 Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763 413999010568 active site 413999010569 Pfam match to entry PF00574 CLP_protease, Clp protease, score 28.8, E-value 1.2e-11 413999010570 aspartate kinase I; Reviewed; Region: PRK08210 413999010571 Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452 413999010572 nucleotide binding site [chemical binding]; other site 413999010573 substrate binding site [chemical binding]; other site 413999010574 ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_1; cd04914 413999010575 ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_2; cd04937 413999010576 Pfam match to entry PF00696 aakinase, Amino acid kinase, score 225.3, E-value 9.3e-65 413999010577 PS00324 Aspartokinase signature. 413999010578 sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888 413999010579 Pfam match to entry PF05239 PRC, PRC-barrel domain,score 28.6, E-value 1.6e-05 413999010580 Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612 413999010581 Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675 413999010582 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 413999010583 Pfam match to entry PF05193 Peptidase_M16_C,Peptidase M16 inactive domain, score 156.1, E-value 6.5e-44 413999010584 Pfam match to entry PF00675 Peptidase_M16,Insulinase (Peptidase M16), score 186.7, E-value 4e-53 413999010585 PS00143 Insulinase, zinc-binding region signature. 413999010586 polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824 413999010587 Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363 413999010588 RNase E interface [polypeptide binding]; other site 413999010589 trimer interface [polypeptide binding]; other site 413999010590 Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726 413999010591 Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364 413999010592 RNase E interface [polypeptide binding]; other site 413999010593 trimer interface [polypeptide binding]; other site 413999010594 active site 413999010595 Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393 413999010596 putative nucleic acid binding region [nucleotide binding]; other site 413999010597 G-X-X-G motif; other site 413999010598 S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472 413999010599 RNA binding site [nucleotide binding]; other site 413999010600 domain interface; other site 413999010601 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 77.5, E-value 2.9e-20 413999010602 Pfam match to entry PF00013 KH, KH domain, score 28.6, E-value 1.6e-05 413999010603 Pfam match to entry PF03725 RNase_PH_C, 3' exoribonuclease, domain 2, score 48.9, E-value 1.2e-11 413999010604 Pfam match to entry PF01138 RNase_PH, 3' exoribonuclease, domain 1, score 172.9, E-value 5.4e-49 413999010605 Pfam match to entry PF03726 PNPase,Polyribonucleotide nucleotidyltransferase, RNA binding domain, score 90.2, E-value 4.3e-24 413999010606 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010607 Pfam match to entry PF03725 RNase_PH_C, 3' exoribonuclease, domain 2, score 46.5, E-value 6.4e-11 413999010608 Pfam match to entry PF01138 RNase_PH, 3' exoribonuclease, domain 1, score 90.2, E-value 4.4e-24 413999010609 Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353 413999010610 16S/18S rRNA binding site [nucleotide binding]; other site 413999010611 S13e-L30e interaction site [polypeptide binding]; other site 413999010612 25S rRNA binding site [nucleotide binding]; other site 413999010613 Pfam match to entry PF00312 Ribosomal_S15,Ribosomal protein S15, score 133.2, E-value 5e-37 413999010614 PS00362 Ribosomal protein S15 signature. 413999010615 bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627 413999010616 FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064 413999010617 active site 413999010618 Riboflavin kinase; Region: Flavokinase; pfam01687 413999010619 Pfam match to entry PF01687 FAD_Synth, Riboflavin kinase / FAD synthetase, score 160.5, E-value 3e-45 413999010620 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010621 tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130 413999010622 Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573 413999010623 RNA binding site [nucleotide binding]; other site 413999010624 active site 413999010625 Predicted helix-turn-helix motif with score 1078.000, SD 2.86 at aa 198-219, sequence FNIKEAIKLEDLNEENIKQYIT 413999010626 Pfam match to entry PF01509 TruB_N, TruB family pseudouridylate synthase (N terminal domain), score 221.0,E-value 1.8e-63 413999010627 Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618 413999010628 DHH family; Region: DHH; pfam01368 413999010629 DHHA1 domain; Region: DHHA1; pfam02272 413999010630 Pfam match to entry PF02272 DHHA1, DHHA1 domain,score 46.5, E-value 6.3e-11 413999010631 Pfam match to entry PF01368 DHH, DHH family, score 90.2, E-value 4.4e-24 413999010632 ribosome-binding factor A; Validated; Region: rbfA; PRK00521 413999010633 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 413999010634 translation initiation factor IF-2; Region: IF-2; TIGR00487 413999010635 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 413999010636 Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887 413999010637 G1 box; other site 413999010638 putative GEF interaction site [polypeptide binding]; other site 413999010639 GTP/Mg2+ binding site [chemical binding]; other site 413999010640 Switch I region; other site 413999010641 G2 box; other site 413999010642 G3 box; other site 413999010643 Switch II region; other site 413999010644 G4 box; other site 413999010645 G5 box; other site 413999010646 This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702 413999010647 Translation-initiation factor 2; Region: IF-2; pfam11987 413999010648 mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692 413999010649 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 26.4, E-value 6.9e-05 413999010650 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 54.9, E-value 1.8e-13 413999010651 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 186.2, E-value 5.5e-53 413999010652 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010653 Pfam match to entry PF04760 IF2_N, Translation initiation factor IF-2, N-terminal region, score 59.4,E-value 7.9e-15 413999010654 Pfam match to entry PF04760 IF2_N, Translation initiation factor IF-2, N-terminal region, score 58.3,E-value 1.8e-14 413999010655 ribosomal protein L7Ae family protein; Provisional; Region: PRK05583 413999010656 Pfam match to entry PF01248 Ribosomal_L7Ae,Ribosomal protein L7Ae/L30e/S12e/Gadd45 family, score 53.0, E-value 6.7e-13 413999010657 Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279 413999010658 putative RNA binding cleft [nucleotide binding]; other site 413999010659 transcription elongation factor NusA; Provisional; Region: nusA; PRK12327 413999010660 NusA N-terminal domain; Region: NusA_N; pfam08529 413999010661 S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455 413999010662 RNA binding site [nucleotide binding]; other site 413999010663 homodimer interface [polypeptide binding]; other site 413999010664 NusA-like KH domain; Region: KH_5; pfam13184 413999010665 NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134 413999010666 G-X-X-G motif; other site 413999010667 Pfam match to entry PF00013 KH, KH domain, score 32.1, E-value 1.4e-06 413999010668 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 18.2, E-value 0.00043 413999010669 Sm and related proteins; Region: Sm_like; cl00259 413999010670 ribosome maturation protein RimP; Reviewed; Region: PRK00092 413999010671 Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734 413999010672 putative oligomer interface [polypeptide binding]; other site 413999010673 putative RNA binding site [nucleotide binding]; other site 413999010674 Pfam match to entry PF02576 DUF150, Uncharacterised BCR, YhbC family COG0779, score 193.1, E-value 4.5e-55 413999010675 DNA polymerase III PolC; Validated; Region: polC; PRK00448 413999010676 DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490 413999010677 polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484 413999010678 generic binding surface II; other site 413999010679 generic binding surface I; other site 413999010680 Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102 413999010681 active site 413999010682 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 413999010683 active site 413999010684 catalytic site [active] 413999010685 substrate binding site [chemical binding]; other site 413999010686 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435 413999010687 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region, score 70.4, E-value 4.1e-18 413999010688 Pfam match to entry PF00929 Exonuclease,Exonuclease, score 182.6, E-value 6.6e-52 413999010689 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region, score 113.5, E-value 4.3e-31 413999010690 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366 413999010691 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694 413999010692 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694 413999010693 Pfam match to entry PF04551 GcpE, GcpE protein,score 712.9, E-value 1.6e-211 413999010694 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010695 Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750 413999010696 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 413999010697 active site 413999010698 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 413999010699 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 413999010700 putative substrate binding region [chemical binding]; other site 413999010701 Pfam match to entry PF02163 Peptidase_M50,Peptidase M50, score 225.8, E-value 6.5e-65 413999010702 4 probable transmembrane helices predicted for CBO2425 by TMHMM2.0 at aa 4-23, 88-110, 272-294 and 307-327 413999010703 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF), score 10.2, E-value 0.05 413999010704 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999010705 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447 413999010706 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670 413999010707 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436 413999010708 DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288 413999010709 Pfam match to entry PF02670 DXP_reductoisom,1-deoxy-D-xylulose 5-phosphate reductoisomerase, score 663.1, E-value 1.5e-196 413999010710 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465 413999010711 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20, score 71.3, E-value 2.2e-18 413999010712 8 probable transmembrane helices predicted for CBO2427 by TMHMM2.0 at aa 11-28, 34-53, 65-87, 149-171,196-218, 228-250, 257-279 and 294-316 413999010713 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 413999010714 Cytidylyltransferase family; Region: CTP_transf_1; pfam01148 413999010715 8 probable transmembrane helices predicted for CBO2430 by TMHMM2.0 at aa 7-29, 49-71, 76-95, 99-121,128-150, 170-192, 199-221 and 241-263 413999010716 Pfam match to entry PF01148 CTP_transf_1,Cytidylyltransferase, score 205.6, E-value 8e-59 413999010717 PS01315 Phosphatidate cytidylyltransferase signature. 413999010718 Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020 413999010719 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475 413999010720 catalytic residue [active] 413999010721 putative FPP diphosphate binding site; other site 413999010722 putative FPP binding hydrophobic cleft; other site 413999010723 dimer interface [polypeptide binding]; other site 413999010724 putative IPP diphosphate binding site; other site 413999010725 Pfam match to entry PF01255 UPP_synthetase,UDP diphosphate synthase, score 374.6,E-value 1.1e-109 413999010726 ribosome recycling factor; Reviewed; Region: frr; PRK00083 413999010727 Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520 413999010728 hinge region; other site 413999010729 Pfam match to entry PF01765 RRF, Ribosome recycling factor, score 307.2, E-value 2.1e-89 413999010730 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010731 UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254 413999010732 putative nucleotide binding site [chemical binding]; other site 413999010733 uridine monophosphate binding site [chemical binding]; other site 413999010734 homohexameric interface [polypeptide binding]; other site 413999010735 Pfam match to entry PF00696 aakinase, Amino acid kinase, score 223.6, E-value 3e-64 413999010736 elongation factor Ts; Provisional; Region: tsf; PRK09377 413999010737 UBA/TS-N domain; Region: UBA; pfam00627 413999010738 Elongation factor TS; Region: EF_TS; pfam00889 413999010739 Elongation factor TS; Region: EF_TS; pfam00889 413999010740 Pfam match to entry PF00889 EF_TS, Elongation factor TS, score 269.0, E-value 6.5e-78 413999010741 Pfam match to entry PF00627 UBA, UBA/TS-N domain,score 55.8, E-value 9.8e-14 413999010742 PS01126 Elongation factor Ts signature 1. 413999010743 Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425 413999010744 rRNA interaction site [nucleotide binding]; other site 413999010745 S8 interaction site; other site 413999010746 putative laminin-1 binding site; other site 413999010747 Pfam match to entry PF00318 Ribosomal_S2, Ribosomal protein S2, score 345.9, E-value 4.5e-101 413999010748 PS00962 Ribosomal protein S2 signature 1. 413999010749 transcriptional repressor CodY; Validated; Region: PRK04158 413999010750 CodY GAF-like domain; Region: CodY; pfam06018 413999010751 CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222 413999010752 Pfam match to entry PF06018 CodY, GTP-sensing transcriptional pleiotropic repressor CodY, score 380.8,E-value 1.5e-111 413999010753 Predicted helix-turn-helix motif with score 1512.000, SD 4.34 at aa 202-223, sequence LVASKIADKVGITRSVIVNALR 413999010754 DNA topoisomerase I; Validated; Region: PRK05582 413999010755 TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I. Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363 413999010756 active site 413999010757 interdomain interaction site; other site 413999010758 putative metal-binding site [ion binding]; other site 413999010759 nucleotide binding site [chemical binding]; other site 413999010760 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 413999010761 domain I; other site 413999010762 DNA binding groove [nucleotide binding] 413999010763 phosphate binding site [ion binding]; other site 413999010764 domain II; other site 413999010765 domain III; other site 413999010766 nucleotide binding site [chemical binding]; other site 413999010767 catalytic site [active] 413999010768 domain IV; other site 413999010769 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 413999010770 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 413999010771 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 413999010772 Pfam match to entry PF01396 zf-C4_Topoisom,Topoisomerase DNA binding C4 zinc finger, score 21.1,E-value 0.0003 413999010773 Pfam match to entry PF01396 zf-C4_Topoisom,Topoisomerase DNA binding C4 zinc finger, score 68.4,E-value 1.6e-17 413999010774 Pfam match to entry PF01396 zf-C4_Topoisom,Topoisomerase DNA binding C4 zinc finger, score 65.1,E-value 1.5e-16 413999010775 Pfam match to entry PF01131 Topoisom_bac, DNA topoisomerase, score 573.8, E-value 1.2e-169 413999010776 PS00396 Prokaryotic DNA topoisomerase I active site. 413999010777 Pfam match to entry PF01751 Toprim, Toprim domain,score 133.2, E-value 5e-37 413999010778 DNA protecting protein DprA; Region: dprA; TIGR00732 413999010779 DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481 413999010780 Pfam match to entry PF02481 SMF, SMF family, score 275.9, E-value 5.3e-80 413999010781 Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606 413999010782 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 413999010783 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999010784 Walker A motif; other site 413999010785 ATP binding site [chemical binding]; other site 413999010786 Walker B motif; other site 413999010787 Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335 413999010788 Pfam match to entry PF01078 Mg_chelatase, Magnesium chelatase, subunit ChlI, score 219.7, E-value 4.5e-63 413999010789 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010790 hypothetical protein; Reviewed; Region: PRK12497 413999010791 Pfam match to entry PF02021 UPF0102,Uncharacterised protein family UPF0102, score 110.0,E-value 4.7e-30 413999010792 bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182 413999010793 RNA/DNA hybrid binding site [nucleotide binding]; other site 413999010794 active site 413999010795 Pfam match to entry PF01351 RNase_HII, Ribonuclease HII, score 193.0, E-value 4.8e-55 413999010796 GTPase YlqF; Reviewed; Region: rbgA; PRK09563 413999010797 Circularly permuted YlqF GTPase; Region: YlqF; cd01856 413999010798 GTP/Mg2+ binding site [chemical binding]; other site 413999010799 G4 box; other site 413999010800 G5 box; other site 413999010801 G1 box; other site 413999010802 Switch I region; other site 413999010803 G2 box; other site 413999010804 G3 box; other site 413999010805 Switch II region; other site 413999010806 Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function, score 239.1, E-value 6.4e-69 413999010807 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010808 signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227 413999010809 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 413999010810 Catalytic site [active] 413999010811 Pfam match to entry PF00461 Peptidase_S26, Signal peptidase I, score 132.1, E-value 1e-36 413999010812 PS00761 Signal peptidases I signature 3. 413999010813 PS00501 Signal peptidases I serine active site. 413999010814 1 probable transmembrane helix predicted for CBO2443 by TMHMM2.0 at aa 15-37 413999010815 50S ribosomal protein L19; Provisional; Region: rplS; PRK05338 413999010816 Pfam match to entry PF01245 Ribosomal_L19,Ribosomal protein L19, score 210.6, E-value 2.5e-60 413999010817 PS01015 Ribosomal protein L19 signature. 413999010818 tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026 413999010819 Pfam match to entry PF01746 tRNA_m1G_MT, tRNA (Guanine-1)-methyltransferase, score 378.1, E-value 9.7e-111 413999010820 16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122 413999010821 RimM N-terminal domain; Region: RimM; pfam01782 413999010822 PRC-barrel domain; Region: PRC; pfam05239 413999010823 Pfam match to entry PF05239 PRC, PRC-barrel domain,score 63.8, E-value 3.9e-16 413999010824 Pfam match to entry PF01782 RimM, RimM N-terminal domain, score 85.6, E-value 1.1e-22 413999010825 Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837 413999010826 hypothetical protein; Provisional; Region: PRK00468 413999010827 Pfam match to entry PF00013 KH, KH domain, score 8.7, E-value 0.062 413999010828 30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040 413999010829 Pfam match to entry PF00886 Ribosomal_S16,Ribosomal protein S16, score 129.1, E-value 8.3e-36 413999010830 PS00732 Ribosomal protein S16 signature. 413999010831 signal recognition particle protein; Provisional; Region: PRK10867 413999010832 SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963 413999010833 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 413999010834 P loop; other site 413999010835 GTP binding site [chemical binding]; other site 413999010836 Signal peptide binding domain; Region: SRP_SPB; pfam02978 413999010837 Pfam match to entry PF02978 SRP_SPB, Signal peptide binding domain, score 166.9, E-value 3.7e-47 413999010838 Pfam match to entry PF00448 SRP54, SRP54-type protein, GTPase domain, score 409.2, E-value 4e-120 413999010839 PS00300 SRP54-type proteins GTP-binding domain signature. 413999010840 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010841 Pfam match to entry PF02881 SRP54_N, SRP54-type protein, helical bundle domain, score 110.1, E-value 4.6e-30 413999010842 putative DNA-binding protein; Validated; Region: PRK00118 413999010843 Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297 413999010844 Pfam match to entry PF04297 UPF0122, helix-turn-helix protein, YlxM / p13 like, score 108.9,E-value 1e-29 413999010845 Predicted helix-turn-helix motif with score 1352.000, SD 3.79 at aa 30-51, sequence YSLKEISELTNTSRQAVHDIVK 413999010846 signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416 413999010847 SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881 413999010848 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999010849 Pfam match to entry PF00448 SRP54, SRP54-type protein, GTPase domain, score 369.2, E-value 4.4e-108 413999010850 PS00300 SRP54-type proteins GTP-binding domain signature. 413999010851 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010852 Pfam match to entry PF02881 SRP54_N, SRP54-type protein, helical bundle domain, score 48.5, E-value 1.6e-11 413999010853 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 413999010854 AAA domain; Region: AAA_23; pfam13476 413999010855 Walker A/P-loop; other site 413999010856 ATP binding site [chemical binding]; other site 413999010857 Q-loop/lid; other site 413999010858 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 413999010859 SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968 413999010860 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 413999010861 Q-loop/lid; other site 413999010862 ABC transporter signature motif; other site 413999010863 Walker B; other site 413999010864 D-loop; other site 413999010865 H-loop/switch region; other site 413999010866 Pfam match to entry PF02483 SMC_C, SMC family,C-terminal domain, score 334.9, E-value 9.7e-98 413999010867 Pfam match to entry PF02524 KID, KID repeat, score 3.1, E-value 74 413999010868 Pfam match to entry PF02524 KID, KID repeat, score 2.5, E-value 97 413999010869 Pfam match to entry PF02524 KID, KID repeat, score 3.8, E-value 52 413999010870 Pfam match to entry PF02524 KID, KID repeat, score 3.9, E-value 49 413999010871 Pfam match to entry PF02524 KID, KID repeat, score 4.7, E-value 33 413999010872 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain, score 274.0, E-value 2e-79 413999010873 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010874 Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729 413999010875 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999010876 FeS/SAM binding site; other site 413999010877 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 97.6, E-value 2.6e-26 413999010878 ribonuclease III; Reviewed; Region: rnc; PRK00102 413999010879 RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593 413999010880 dimerization interface [polypeptide binding]; other site 413999010881 active site 413999010882 metal binding site [ion binding]; metal-binding site 413999010883 Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048 413999010884 dsRNA binding site [nucleotide binding]; other site 413999010885 Pfam match to entry PF00035 dsrm, Double-stranded RNA binding motif, score 84.5, E-value 2.2e-22 413999010886 Pfam match to entry PF00636 Ribonuclease_3, RNase3 domain, score 172.7, E-value 6.3e-49 413999010887 PS00517 Ribonuclease III family signature. 413999010888 acyl carrier protein; Provisional; Region: acpP; PRK00982 413999010889 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999010890 Pfam match to entry PF00550 pp-binding,Phosphopantetheine attachment site, score 80.9, E-value 2.8e-21 413999010891 PS00012 Phosphopantetheine attachment site. 413999010892 putative phosphate acyltransferase; Provisional; Region: PRK05331 413999010893 Pfam match to entry PF02504 FA_synthesis, Fatty acid synthesis protein, score 473.6, E-value 1.7e-139 413999010894 50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286 413999010895 Pfam match to entry PF01783 Ribosomal_L32p,Ribosomal L32p protein family, score 48.7, E-value 1.3e-11 413999010896 Pfam match to entry PF02620 DUF177, Uncharacterized ACR, COG1399, score 111.0, E-value 2.3e-30 413999010897 acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180 413999010898 propionate/acetate kinase; Provisional; Region: PRK12379 413999010899 Pfam match to entry PF00871 Acetate_kinase,Acetokinase, score 811.7, E-value 2.8e-241 413999010900 PS01076 Acetate and butyrate kinases family signature 2. 413999010901 PS01075 Acetate and butyrate kinases family signature 1. 413999010902 phosphotransacetylase; Reviewed; Region: eutD; PRK09653 413999010903 Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase, score 665.3, E-value 3.3e-197 413999010904 repetetive region carrying several proline reductases 413999010905 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 413999010906 9 probable transmembrane helices predicted for CBO2460 by TMHMM2.0 at aa 4-21, 38-60, 75-97, 104-126,136-158, 170-192, 207-225, 237-256 and 261-280 413999010907 glycine reductase, selenoprotein B; Region: gly_red_sel_B; TIGR01917 413999010908 Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338 413999010909 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010910 RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375 413999010911 Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512 413999010912 Pfam match to entry PF01512 Complex1_51K,Respiratory-chain NADH dehydrogenase 51 Kd subunit, score 65.0, E-value 1.6e-16 413999010913 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 413999010914 9 probable transmembrane helices predicted for CBO2467 by TMHMM2.0 at aa 5-22, 37-59, 79-101, 105-127,134-156, 171-193, 198-220, 240-257 and 264-281 413999010915 Cache domain; Region: Cache_1; pfam02743 413999010916 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999010917 dimerization interface [polypeptide binding]; other site 413999010918 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999010919 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999010920 dimer interface [polypeptide binding]; other site 413999010921 putative CheW interface [polypeptide binding]; other site 413999010922 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 189.2, E-value 6.9e-54 413999010923 Pfam match to entry PF00672 HAMP, HAMP domain,score 56.4, E-value 6.3e-14 413999010924 2 probable transmembrane helices predicted for CBO2468 by TMHMM2.0 at aa 13-35 and 293-315 413999010925 Pfam match to entry PF02743 Cache, Cache domain,score 43.5, E-value 5e-10 413999010926 Uncharacterized conserved protein [Function unknown]; Region: COG1915 413999010927 Saccharopine dehydrogenase N-terminal domain; Region: SDH_N_domain; cl04528 413999010928 Uncharacterized conserved protein [Function unknown]; Region: COG1915 413999010929 putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813 413999010930 Pfam match to entry PF00324 aa_permeases, Amino acid permease, score -2.1, E-value 1e-07 413999010931 11 probable transmembrane helices predicted for CBO2472 by TMHMM2.0 at aa 10-27, 34-56, 87-109, 118-140,150-172, 229-251, 278-300, 327-349, 354-376, 406-428 and 438-457 413999010932 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 413999010933 9 probable transmembrane helices predicted for CBO2473 by TMHMM2.0 at aa 5-22, 37-59, 79-101, 105-127,134-156, 171-193, 198-220, 240-257 and 264-281 413999010934 proline racemase; Provisional; Region: PRK13969 413999010935 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 413999010936 Pfam match to entry PF05544 Pro_racemase, Proline racemase, score 549.4, E-value 2.5e-162 413999010937 Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338 413999010938 Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338 413999010939 glycine reductase, selenoprotein B; Region: gly_red_sel_B; TIGR01917 413999010940 Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338 413999010941 PS00017 ATP/GTP-binding site motif A (P-loop). 413999010942 RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375 413999010943 Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512 413999010944 SLBB domain; Region: SLBB; pfam10531 413999010945 Pfam match to entry PF01512 Complex1_51K,Respiratory-chain NADH dehydrogenase 51 Kd subunit, score 53.8, E-value 9.1e-16 413999010946 RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375 413999010947 Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512 413999010948 SLBB domain; Region: SLBB; pfam10531 413999010949 Pfam match to entry PF01512 Complex1_51K,Respiratory-chain NADH dehydrogenase 51 Kd subunit, score 62.9, E-value 2.3e-16 413999010950 Predicted permease; Region: DUF318; cl17795 413999010951 5 probable transmembrane helices predicted for CBO2486 by TMHMM2.0 at aa 2-19, 39-58, 71-93, 103-125 and 137-158 413999010952 Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512 413999010953 Pfam match to entry PF01512 Complex1_51K,Respiratory-chain NADH dehydrogenase 51 Kd subunit, score 37.0, E-value 1.2e-14 413999010954 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 413999010955 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829 413999010956 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999010957 putative active site [active] 413999010958 heme pocket [chemical binding]; other site 413999010959 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999010960 Walker A motif; other site 413999010961 ATP binding site [chemical binding]; other site 413999010962 Walker B motif; other site 413999010963 arginine finger; other site 413999010964 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999010965 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 60.9, E-value 3e-15 413999010966 Predicted helix-turn-helix motif with score 2006.000, SD 6.02 at aa 558-579, sequence GNKKKAAEILNIKRSTLYYKLN 413999010967 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 395.5, E-value 5.5e-116 413999010968 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999010969 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999010970 Pfam match to entry PF00989 PAS, PAS domain, score 29.6, E-value 7.5e-06 413999010971 Pfam match to entry PF00571 CBS, CBS domain, score 49.9, E-value 5.9e-12 413999010972 Pfam match to entry PF00571 CBS, CBS domain, score 33.9, E-value 3.9e-07 413999010973 hypothetical protein; Provisional; Region: PRK13670 413999010974 HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673 413999010975 Pfam match to entry PF05636 DUF795, Protein of unknown function (DUF795), score 487.5, E-value 1.1e-143 413999010976 sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871 413999010977 Nucleoside recognition; Region: Gate; pfam07670 413999010978 8 probable transmembrane helices predicted for CBO2492 by TMHMM2.0 at aa 3-20, 25-47, 60-82, 162-184,214-236, 288-310, 323-344 and 359-381 413999010979 phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168 413999010980 Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163 413999010981 active site 413999010982 (T/H)XGH motif; other site 413999010983 Pfam match to entry PF01467 CTP_transf_2,Cytidylyltransferase, score 128.4, E-value 1.4e-35 413999010984 Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602 413999010985 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999010986 S-adenosylmethionine binding site [chemical binding]; other site 413999010987 Pfam match to entry PF03602 Cons_hypoth95,hypothetical protein 95, score 269.6, E-value 4.4e-78 413999010988 PS00092 N-6 Adenine-specific DNA methylases signature. 413999010989 ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917 413999010990 RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488 413999010991 ssDNA binding site; other site 413999010992 generic binding surface II; other site 413999010993 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999010994 ATP binding site [chemical binding]; other site 413999010995 putative Mg++ binding site [ion binding]; other site 413999010996 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999010997 nucleotide binding region [chemical binding]; other site 413999010998 ATP-binding site [chemical binding]; other site 413999010999 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 84.8, E-value 1.9e-22 413999011000 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 120.4, E-value 3.5e-33 413999011001 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011002 DAK2 domain fusion protein YloV; Region: YloV; TIGR03599 413999011003 DAK2 domain; Region: Dak2; pfam02734 413999011004 Pfam match to entry PF02734 Dak2, DAK2 domain,score 193.7, E-value 3e-55 413999011005 Asp23 family; Region: Asp23; pfam03780 413999011006 Pfam match to entry PF03780 DUF322, Protein of unknown function (DUF322), score 134.9, E-value 1.5e-37 413999011007 50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359 413999011008 Pfam match to entry PF00830 Ribosomal_L28,Ribosomal L28 family, score 71.3, E-value 2.1e-18 413999011009 Thiamine pyrophosphokinase; Region: TPK; cd07995 413999011010 active site 413999011011 thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378 413999011012 dimerization interface [polypeptide binding]; other site 413999011013 thiamine binding site [chemical binding]; other site 413999011014 Pfam match to entry PF04263 TPK_catalytic, Thiamin pyrophosphokinase, catalytic domain, score 151.1, E-value 2e-42 413999011015 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036 413999011016 Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429 413999011017 substrate binding site [chemical binding]; other site 413999011018 hexamer interface [polypeptide binding]; other site 413999011019 metal binding site [ion binding]; metal-binding site 413999011020 Pfam match to entry PF00834 Ribul_P_3_epim,Ribulose-phosphate 3 epimerase, score 385.6,E-value 5.3e-113 413999011021 PS01085 Ribulose-phosphate 3-epimerase signature 1. 413999011022 S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466 413999011023 GTPase RsgA; Reviewed; Region: PRK00098 413999011024 RNA binding site [nucleotide binding]; other site 413999011025 homodimer interface [polypeptide binding]; other site 413999011026 Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854 413999011027 GTPase/Zn-binding domain interface [polypeptide binding]; other site 413999011028 GTP/Mg2+ binding site [chemical binding]; other site 413999011029 G4 box; other site 413999011030 G5 box; other site 413999011031 G1 box; other site 413999011032 Switch I region; other site 413999011033 G2 box; other site 413999011034 G3 box; other site 413999011035 Switch II region; other site 413999011036 Pfam match to entry PF03193 DUF258, Protein of unknown function, DUF258, score 188.2, E-value 1.3e-53 413999011037 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011038 Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220 413999011039 Catalytic domain of Protein Kinases; Region: PKc; cd00180 413999011040 active site 413999011041 ATP binding site [chemical binding]; other site 413999011042 substrate binding site [chemical binding]; other site 413999011043 activation loop (A-loop); other site 413999011044 PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577 413999011045 PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577 413999011046 PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577 413999011047 Pfam match to entry PF03793 PASTA, PASTA domain,score 42.6, E-value 9.1e-10 413999011048 Pfam match to entry PF03793 PASTA, PASTA domain,score 64.0, E-value 3.4e-16 413999011049 Pfam match to entry PF03793 PASTA, PASTA domain,score 65.3, E-value 1.3e-16 413999011050 1 probable transmembrane helix predicted for CBO2504 by TMHMM2.0 at aa 355-377 413999011051 Pfam match to entry PF00069 pkinase, Protein kinase domain, score 230.0, E-value 3.6e-66 413999011052 PS00108 Serine/Threonine protein kinases active-site signature. 413999011053 PS00107 Protein kinases ATP-binding region signature. 413999011054 Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143 413999011055 active site 413999011056 Pfam match to entry PF00481 PP2C, Protein phosphatase 2C, score 43.9, E-value 3.6e-10 413999011057 ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14454 413999011058 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999011059 FeS/SAM binding site; other site 413999011060 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 63.3, E-value 5.5e-16 413999011061 16S rRNA methyltransferase B; Provisional; Region: PRK14902 413999011062 NusB family; Region: NusB; pfam01029 413999011063 putative RNA binding site [nucleotide binding]; other site 413999011064 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999011065 S-adenosylmethionine binding site [chemical binding]; other site 413999011066 Pfam match to entry PF01189 Nol1_Nop2_Sun,NOL1/NOP2/sun family, score 199.1, E-value 7.2e-57 413999011067 Pfam match to entry PF01029 NusB, NusB family,score 83.7, E-value 4e-22 413999011068 Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298 413999011069 Pfam match to entry PF04298 Zn_peptidase_2,neutral zinc metallopeptidase, score 463.5,E-value 1.9e-136 413999011070 4 probable transmembrane helices predicted for CBO2508 by TMHMM2.0 at aa 12-34, 131-153, 160-178 and 210-232 413999011071 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999011072 methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005 413999011073 Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646 413999011074 putative active site [active] 413999011075 substrate binding site [chemical binding]; other site 413999011076 putative cosubstrate binding site; other site 413999011077 catalytic site [active] 413999011078 C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704 413999011079 substrate binding site [chemical binding]; other site 413999011080 Pfam match to entry PF02911 formyl_trans_C, Formyl transferase, C-terminal domain, score 115.0, E-value 1.5e-31 413999011081 Pfam match to entry PF00551 formyl_transf, Formyl transferase, score 163.6, E-value 3.5e-46 413999011082 PS00373 Phosphoribosylglycinamide formyltransferase active site. 413999011083 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 413999011084 active site 413999011085 catalytic residues [active] 413999011086 metal binding site [ion binding]; metal-binding site 413999011087 Pfam match to entry PF01327 Pep_deformylase,Polypeptide deformylase, score 256.1, E-value 4.9e-74 413999011088 primosome assembly protein PriA; Validated; Region: PRK05580 413999011089 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999011090 ATP binding site [chemical binding]; other site 413999011091 putative Mg++ binding site [ion binding]; other site 413999011092 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999011093 nucleotide binding region [chemical binding]; other site 413999011094 ATP-binding site [chemical binding]; other site 413999011095 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 29.7, E-value 7.2e-06 413999011096 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011097 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579 413999011098 Flavoprotein; Region: Flavoprotein; pfam02441 413999011099 DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127 413999011100 Pfam match to entry PF04127 dfp, DNA / pantothenate metabolism flavoprotein, score 133.2, E-value 5e-37 413999011101 PS00107 Protein kinases ATP-binding region signature. 413999011102 Pfam match to entry PF02441 Flavoprotein,Flavoprotein, score 159.5, E-value 5.9e-45 413999011103 DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392 413999011104 Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194 413999011105 Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071 413999011106 catalytic site [active] 413999011107 G-X2-G-X-G-K; other site 413999011108 Pfam match to entry PF00625 Guanylate_kin,Guanylate kinase, score 147.9, E-value 1.9e-41 413999011109 PS00856 Guanylate kinase signature. 413999011110 hypothetical protein; Provisional; Region: PRK04323 413999011111 Pfam match to entry PF04025 DUF370, Domain of unknown function (DUF370), score 216.0, E-value 6e-62 413999011112 hypothetical protein; Provisional; Region: PRK11820 413999011113 YicC-like family, N-terminal region; Region: YicC_N; pfam03755 413999011114 Domain of unknown function (DUF1732); Region: DUF1732; pfam08340 413999011115 Pfam match to entry PF03755 YicC_N-term, YicC-like family, N-terminal region, score 198.8, E-value 8.7e-57 413999011116 PS00217 Sugar transport proteins signature 2. 413999011117 Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964 413999011118 active site 413999011119 homotetramer interface [polypeptide binding]; other site 413999011120 homodimer interface [polypeptide binding]; other site 413999011121 Pfam match to entry PF00710 Asparaginase,Asparaginase, score 251.8, E-value 9.9e-73 413999011122 Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443 413999011123 sequence-specific DNA binding site [nucleotide binding]; other site 413999011124 salt bridge; other site 413999011125 Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547 413999011126 stage IV sporulation protein A; Region: spore_IV_A; TIGR02836 413999011127 PS00294 Prenyl group binding site (CAAX box). 413999011128 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011129 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094 413999011130 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 413999011131 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479 413999011132 Pfam match to entry PF01210 NAD_Gly3P_dh,NAD-dependent glycerol-3-phosphate dehydrogenase, score 487.3, E-value 1.3e-143 413999011133 PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 413999011134 GTP-binding protein Der; Reviewed; Region: PRK00093 413999011135 EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894 413999011136 G1 box; other site 413999011137 GTP/Mg2+ binding site [chemical binding]; other site 413999011138 Switch I region; other site 413999011139 G2 box; other site 413999011140 Switch II region; other site 413999011141 G3 box; other site 413999011142 G4 box; other site 413999011143 G5 box; other site 413999011144 EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895 413999011145 G1 box; other site 413999011146 GTP/Mg2+ binding site [chemical binding]; other site 413999011147 Switch I region; other site 413999011148 G2 box; other site 413999011149 G3 box; other site 413999011150 Switch II region; other site 413999011151 G4 box; other site 413999011152 G5 box; other site 413999011153 Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function, score 224.5, E-value 1.6e-64 413999011154 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011155 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011156 putative FeS-containing Cyanobacterial-specific oxidoreductase; Region: cyano_FeS_chp; TIGR03279 413999011157 PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117 413999011158 Protein of unknown function (DUF512); Region: DUF512; pfam04459 413999011159 Pfam match to entry PF04459 DUF512, Protein of unknown function (DUF512), score 179.4, E-value 6.2e-51 413999011160 phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135 413999011161 PhoU domain; Region: PhoU; pfam01895 413999011162 PhoU domain; Region: PhoU; pfam01895 413999011163 Pfam match to entry PF01895 PhoU, PhoU family,score 83.3, E-value 5.1e-22 413999011164 Pfam match to entry PF01895 PhoU, PhoU family,score 120.3, E-value 3.9e-33 413999011165 phosphate transporter ATP-binding protein; Provisional; Region: PRK14240 413999011166 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 413999011167 Walker A/P-loop; other site 413999011168 ATP binding site [chemical binding]; other site 413999011169 Q-loop/lid; other site 413999011170 ABC transporter signature motif; other site 413999011171 Walker B; other site 413999011172 D-loop; other site 413999011173 H-loop/switch region; other site 413999011174 Pfam match to entry PF00005 ABC_tran, ABC transporter score 201.3, E-value 1.5e-57 413999011175 PS00211 ABC transporters family signature. 413999011176 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011177 ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581 413999011178 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999011179 dimer interface [polypeptide binding]; other site 413999011180 conserved gate region; other site 413999011181 putative PBP binding loops; other site 413999011182 ABC-ATPase subunit interface; other site 413999011183 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 115.5, E-value 1.1e-31 413999011184 6 probable transmembrane helices predicted for CBO2523 by TMHMM2.0 at aa 12-34, 65-87, 99-121, 126-148,181-203 and 257-279 413999011185 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999011186 phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138 413999011187 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999011188 dimer interface [polypeptide binding]; other site 413999011189 conserved gate region; other site 413999011190 putative PBP binding loops; other site 413999011191 ABC-ATPase subunit interface; other site 413999011192 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 82.1, E-value 1.2e-21 413999011193 6 probable transmembrane helices predicted for CBO2524 by TMHMM2.0 at aa 30-52, 94-116, 129-151, 161-183,220-242 and 279-301 413999011194 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999011195 PBP superfamily domain; Region: PBP_like_2; cl17296 413999011196 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 42.0, E-value 1.4e-09 413999011197 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999011198 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999011199 dimerization interface [polypeptide binding]; other site 413999011200 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 413999011201 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999011202 putative active site [active] 413999011203 heme pocket [chemical binding]; other site 413999011204 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999011205 dimer interface [polypeptide binding]; other site 413999011206 phosphorylation site [posttranslational modification] 413999011207 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999011208 ATP binding site [chemical binding]; other site 413999011209 Mg2+ binding site [ion binding]; other site 413999011210 G-X-G motif; other site 413999011211 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 149.3, E-value 7.2e-42 413999011212 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 85.8, E-value 8.9e-23 413999011213 Pfam match to entry PF00672 HAMP, HAMP domain,score 66.5, E-value 6.1e-17 413999011214 2 probable transmembrane helices predicted for CBO2526 by TMHMM2.0 at aa 5-27 and 157-179 413999011215 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999011216 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999011217 active site 413999011218 phosphorylation site [posttranslational modification] 413999011219 intermolecular recognition site; other site 413999011220 dimerization interface [polypeptide binding]; other site 413999011221 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999011222 DNA binding site [nucleotide binding] 413999011223 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 104.3, E-value 2.4e-28 413999011224 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 150.2, E-value 3.8e-42 413999011225 Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578 413999011226 Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496 413999011227 Pfam match to entry PF02578 DUF152, Uncharacterised ACR, YfiH family COG1496, score 162.6, E-value 7.1e-46 413999011228 transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464 413999011229 ATP cone domain; Region: ATP-cone; pfam03477 413999011230 Pfam match to entry PF03477 ATP-cone, ATP cone domain, score 99.1, E-value 9.3e-27 413999011231 Protein implicated in RNA metabolism, contains PRC-barrel domain [General function prediction only]; Region: COG1873; cl17889 413999011232 Pfam match to entry PF05239 PRC, PRC-barrel domain,score 38.9, E-value 1.2e-08 413999011233 sporulation sigma factor SigG; Reviewed; Region: PRK08215 413999011234 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999011235 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 413999011236 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999011237 DNA binding residues [nucleotide binding] 413999011238 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 60.9, E-value 3e-15 413999011239 PS00716 Sigma-70 factors family signature 2. 413999011240 Predicted helix-turn-helix motif with score 2314.000, SD 7.07 at aa 226-247, sequence RTQMEVADEIGISQAQVSRLEK 413999011241 Pfam match to entry PF04539 sigma70_r3, Sigma-70 region 3, score 19.7, E-value 0.00025 413999011242 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 82.8, E-value 7.1e-22 413999011243 PS00715 Sigma-70 factors family signature 1. 413999011244 sporulation sigma factor SigE; Reviewed; Region: PRK08301 413999011245 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999011246 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999011247 DNA binding residues [nucleotide binding] 413999011248 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 79.5, E-value 7.5e-21 413999011249 PS00716 Sigma-70 factors family signature 2. 413999011250 Predicted helix-turn-helix motif with score 2672.000, SD 8.29 at aa 200-221, sequence KTQKEVADMLGISQSYISRLEK 413999011251 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 73.4, E-value 4.9e-19 413999011252 PS00715 Sigma-70 factors family signature 1. 413999011253 Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419 413999011254 sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854 413999011255 Pfam match to entry PF03419 Peptidase_U4,Sporulation factor SpoIIGA, score 276.8, E-value 2.9e-80 413999011256 5 probable transmembrane helices predicted for CBO2534 by TMHMM2.0 at aa 4-21, 33-52, 57-76, 83-105 and 125-144 413999011257 cell division protein FtsZ; Validated; Region: PRK09330 413999011258 FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201 413999011259 nucleotide binding site [chemical binding]; other site 413999011260 SulA interaction site; other site 413999011261 Pfam match to entry PF03953 tubulin_C, Tubulin/FtsZ family, C-terminal domain, score 137.6, E-value 2.3e-38 413999011262 Pfam match to entry PF00091 tubulin, Tubulin/FtsZ family, GTPase domain, score 338.8, E-value 6.2e-99 413999011263 PS01135 FtsZ protein signature 2. 413999011264 PS01134 FtsZ protein signature 1. 413999011265 Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849 413999011266 Cell division protein FtsA; Region: FtsA; smart00842 413999011267 Cell division protein FtsA; Region: FtsA; pfam14450 413999011268 Pfam match to entry PF02491 FtsA, Cell division protein FtsA, score 80.3, E-value 4.1e-21 413999011269 Pfam match to entry PF02491 FtsA, Cell division protein FtsA, score 102.0, E-value 1.2e-27 413999011270 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 413999011271 EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438 413999011272 DXD motif; other site 413999011273 4 probable transmembrane helices predicted for CBO2537 by TMHMM2.0 at aa 15-34, 304-326, 346-368 and 377-399 413999011274 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 42.7, E-value 8.5e-10 413999011275 Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805 413999011276 Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131 413999011277 Walker A motif; other site 413999011278 ATP binding site [chemical binding]; other site 413999011279 Walker B motif; other site 413999011280 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein, score 73.7, E-value 4.1e-19 413999011281 PS00662 Bacterial type II secretion system protein E signature. 413999011282 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011283 shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258 413999011284 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 413999011285 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 413999011286 shikimate binding site; other site 413999011287 NAD(P) binding site [chemical binding]; other site 413999011288 Pfam match to entry PF01488 Shikimate_DH, Shikimate / quinate 5-dehydrogenase, score 194.9, E-value 1.3e-55 413999011289 sporulation sigma factor SigK; Reviewed; Region: PRK05803 413999011290 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999011291 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999011292 DNA binding residues [nucleotide binding] 413999011293 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 66.3, E-value 6.8e-17 413999011294 PS00716 Sigma-70 factors family signature 2. 413999011295 Predicted helix-turn-helix motif with score 2302.000, SD 7.03 at aa 197-218, sequence RTQREIAGILNISRSYVSRIEK 413999011296 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 70.5, E-value 3.6e-18 413999011297 PS00715 Sigma-70 factors family signature 1. 413999011298 Domain of unknown function (DUF2382); Region: DUF2382; pfam09557 413999011299 Domain of unknown function (DUF2382); Region: DUF2382; cl01590 413999011300 PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684 413999011301 RecT family; Region: RecT; pfam03837 413999011302 Pfam match to entry PF03837 RecT, RecT family,score 43.2, E-value 6.2e-10 413999011303 PS00327 Bacterial rhodopsins retinal binding site. 413999011304 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 50.9, E-value 3e-12 413999011305 Predicted helix-turn-helix motif with score 2048.000, SD 6.16 at aa 51-72, sequence ITTYELSELIGIPQSTISKIEN 413999011306 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999011307 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 413999011308 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 413999011309 Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain, score 141.7, E-value 1.4e-39 413999011310 1 probable transmembrane helix predicted for CBO2553 by TMHMM2.0 at aa 9-28 413999011311 Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572 413999011312 Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023 413999011313 ATP-binding site [chemical binding]; other site 413999011314 Sugar specificity; other site 413999011315 Pyrimidine base specificity; other site 413999011316 Pfam match to entry PF00485 PRK,Phosphoribulokinase / Uridine kinase, score 171.6,E-value 1.4e-48 413999011317 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011318 Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826 413999011319 Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615 413999011320 Peptidase family U32; Region: Peptidase_U32; pfam01136 413999011321 Pfam match to entry PF01136 Peptidase_U32,Peptidase U32, score 493.6, E-value 1.6e-145 413999011322 PS01276 Peptidase U32 signature. 413999011323 Predicted O-methyltransferase [General function prediction only]; Region: COG4122 413999011324 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999011325 S-adenosylmethionine binding site [chemical binding]; other site 413999011326 Pfam match to entry PF01596 Methyltransf_3,O-methyltransferase, score 44.6, E-value 4.5e-16 413999011327 YceG-like family; Region: YceG; pfam02618 413999011328 proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010 413999011329 dimerization interface [polypeptide binding]; other site 413999011330 Pfam match to entry PF02618 ADC_lyase,Aminodeoxychorismate lyase, score 366.6, E-value 2.7e-107 413999011331 1 probable transmembrane helix predicted for CBO2557 by TMHMM2.0 at aa 7-25 413999011332 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999011333 Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217 413999011334 Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891 413999011335 G1 box; other site 413999011336 putative GEF interaction site [polypeptide binding]; other site 413999011337 GTP/Mg2+ binding site [chemical binding]; other site 413999011338 Switch I region; other site 413999011339 G2 box; other site 413999011340 G3 box; other site 413999011341 Switch II region; other site 413999011342 G4 box; other site 413999011343 G5 box; other site 413999011344 BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu. BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691 413999011345 BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants. BipA is a highly...; Region: BipA_TypA_C; cd03710 413999011346 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus, score 116.8, E-value 4.4e-32 413999011347 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 54.3, E-value 2.8e-13 413999011348 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 236.0, E-value 5.6e-68 413999011349 PS00301 GTP-binding elongation factors signature. 413999011350 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011351 mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595 413999011352 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999011353 RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521 413999011354 PS01292 Uncharacterized protein family UPF0036 signature. 413999011355 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 95.2, E-value 1.3e-25 413999011356 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 413999011357 metal binding site 2 [ion binding]; metal-binding site 413999011358 putative DNA binding helix; other site 413999011359 metal binding site 1 [ion binding]; metal-binding site 413999011360 dimer interface [polypeptide binding]; other site 413999011361 structural Zn2+ binding site [ion binding]; other site 413999011362 Pfam match to entry PF01475 FUR, Ferric uptake regulator family, score 183.4, E-value 3.8e-52 413999011363 Protein of unknown function (DUF1292); Region: DUF1292; pfam06949 413999011364 Holliday junction resolvase-like protein; Reviewed; Region: PRK00109 413999011365 Pfam match to entry PF03652 UPF0081,Uncharacterised protein family (UPF0081), score 181.3,E-value 1.6e-51 413999011366 hypothetical protein; Provisional; Region: PRK05473 413999011367 Pfam match to entry PF06135 DUF965, Bacterial protein of unknown function (DUF965), score 153.4, E-value 4.1e-43 413999011368 alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252 413999011369 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673 413999011370 motif 1; other site 413999011371 active site 413999011372 motif 2; other site 413999011373 motif 3; other site 413999011374 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 413999011375 Pfam match to entry PF02272 DHHA1, DHHA1 domain,score 83.3, E-value 5.2e-22 413999011376 Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A), score 1183.3, E-value 0 413999011377 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999011378 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 413999011379 Domain of unknown function DUF20; Region: UPF0118; pfam01594 413999011380 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20, score 216.3, E-value 4.8e-62 413999011381 8 probable transmembrane helices predicted for CBO2565 by TMHMM2.0 at aa 7-26, 30-49, 68-90, 164-186,206-228, 241-263, 270-287 and 302-324 413999011382 PRC-barrel domain containing protein [General function prediction only]; Region: COG3881 413999011383 PRC-barrel domain; Region: PRC; pfam05239 413999011384 Pfam match to entry PF05239 PRC, PRC-barrel domain,score 23.4, E-value 6.5e-06 413999011385 NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822 413999011386 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 413999011387 trimerization site [polypeptide binding]; other site 413999011388 active site 413999011389 Pfam match to entry PF01592 NifU_N, NifU-like N terminal domain, score 251.4, E-value 1.3e-72 413999011390 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 413999011391 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 413999011392 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999011393 catalytic residue [active] 413999011394 Pfam match to entry PF00266 aminotran_5,Aminotransferase class-V, score 404.9, E-value 8.2e-119 413999011395 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 413999011396 Transcriptional regulator; Region: Rrf2; cl17282 413999011397 Rrf2 family protein; Region: rrf2_super; TIGR00738 413999011398 Pfam match to entry PF02082 Rrf2, Transcriptional regulator, score 177.6, E-value 2.2e-50 413999011399 Predicted helix-turn-helix motif with score 988.000, SD 2.55 at aa 26-47, sequence VSIKNISERQHISEYYLEQLFS 413999011400 recombination factor protein RarA; Reviewed; Region: PRK13342 413999011401 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999011402 Walker A motif; other site 413999011403 ATP binding site [chemical binding]; other site 413999011404 Walker B motif; other site 413999011405 arginine finger; other site 413999011406 MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002 413999011407 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 38.5, E-value 1.6e-08 413999011408 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011409 histidinol-phosphatase; Provisional; Region: PRK05588 413999011410 Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102 413999011411 active site 413999011412 Predicted permeases [General function prediction only]; Region: COG0679 413999011413 10 probable transmembrane helices predicted for CBO2572 by TMHMM2.0 at aa 5-23, 36-58, 68-90, 97-119,124-146, 158-180, 186-208, 221-243, 248-270 and 277-299 413999011414 Pfam match to entry PF03547 Auxin_eff, Auxin Efflux Carrier, score 134.2, E-value 2.5e-37 413999011415 EDD domain protein, DegV family; Region: DegV; TIGR00762 413999011416 Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645 413999011417 Pfam match to entry PF02645 DUF194, Uncharacterized protein, DegV family COG1307, score 257.1, E-value 2.5e-74 413999011418 SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain. The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY, and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421 413999011419 selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527 413999011420 CPxP motif; other site 413999011421 DsrE/DsrF-like family; Region: DrsE; pfam02635 413999011422 Pfam match to entry PF01206 UPF0033,Uncharacterized protein family UPF0033, score 9.6, E-value 5.5e-05 413999011423 ornithine cyclodeaminase; Validated; Region: PRK08618 413999011424 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 413999011425 Pfam match to entry PF02423 ODC_Mu_crystall,Ornithine cyclodeaminase/mu-crystallin family, score 271.0, E-value 1.6e-78 413999011426 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999011427 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 413999011428 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 506.3, E-value 2.5e-149 413999011429 9 probable transmembrane helices predicted for CBO2576 by TMHMM2.0 at aa 15-37, 77-99, 148-170, 177-199,209-231, 297-319, 349-371, 384-406 and 411-430 413999011430 PS00873 Sodium:alanine symporter family signature. 413999011431 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999011432 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 413999011433 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 543.5, E-value 1.5e-160 413999011434 11 probable transmembrane helices predicted for CBO2577 by TMHMM2.0 at aa 15-37, 58-77, 92-114, 144-163,176-198, 210-229, 239-258, 297-319, 349-371, 384-406 and 411-430 413999011435 PS00873 Sodium:alanine symporter family signature. 413999011436 Domain of unknown function (DUF4397); Region: DUF4397; pfam14344 413999011437 Domain of unknown function (DUF4397); Region: DUF4397; pfam14344 413999011438 Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833 413999011439 1 probable transmembrane helix predicted for CBO2579 by TMHMM2.0 at aa 5-27 413999011440 phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857 413999011441 AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019 413999011442 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203 413999011443 dimerization interface [polypeptide binding]; other site 413999011444 ATP binding site [chemical binding]; other site 413999011445 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204 413999011446 dimerization interface [polypeptide binding]; other site 413999011447 ATP binding site [chemical binding]; other site 413999011448 Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740 413999011449 putative active site [active] 413999011450 catalytic triad [active] 413999011451 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain, score 106.0, E-value 7.4e-29 413999011452 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain, score 17.0, E-value 0.00019 413999011453 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999011454 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 413999011455 10 probable transmembrane helices predicted for CBO2581 by TMHMM2.0 at aa 21-43, 58-80, 101-123, 143-160,173-195, 201-223, 286-308, 323-342, 363-385 and 421-440 413999011456 Pfam match to entry PF01554 MatE, MatE, score 78.5,E-value 1.4e-20 413999011457 phosphoenolpyruvate synthase; Validated; Region: PRK06241 413999011458 Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326 413999011459 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 413999011460 Pfam match to entry PF00391 PEP-utilizers,PEP-utilising enzyme, mobile domain, score 129.7, E-value 5.5e-36 413999011461 Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain, score 324.8, E-value 1.1e-94 413999011462 Phosphopantetheine attachment site; Region: PP-binding; cl09936 413999011463 PS00018 EF-hand calcium-binding domain. 413999011464 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 413999011465 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 413999011466 active site 413999011467 AMP binding site [chemical binding]; other site 413999011468 acyl-activating enzyme (AAE) consensus motif; other site 413999011469 CoA binding site [chemical binding]; other site 413999011470 Pfam match to entry PF00501 AMP-binding,AMP-binding enzyme, score 15.1, E-value 2.1e-07 413999011471 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011472 2 probable transmembrane helices predicted for CBO2584 by TMHMM2.0 at aa 73-92 and 197-216 413999011473 3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332 413999011474 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 413999011475 dimer interface [polypeptide binding]; other site 413999011476 active site 413999011477 CoA binding pocket [chemical binding]; other site 413999011478 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 413999011479 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 413999011480 AMP-binding enzyme; Region: AMP-binding; pfam00501 413999011481 acyl-activating enzyme (AAE) consensus motif; other site 413999011482 AMP binding site [chemical binding]; other site 413999011483 active site 413999011484 CoA binding site [chemical binding]; other site 413999011485 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 413999011486 Pfam match to entry PF00550 pp-binding,Phosphopantetheine attachment site, score 47.1, E-value 4.2e-11 413999011487 Pfam match to entry PF00501 AMP-binding,AMP-binding enzyme, score 241.1, E-value 1.6e-69 413999011488 PS00455 AMP-binding domain signature. 413999011489 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 413999011490 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999011491 Coenzyme A binding pocket [chemical binding]; other site 413999011492 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 22.0, E-value 0.0014 413999011493 Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide; Region: AANH_like; cl00292 413999011494 Ligand Binding Site [chemical binding]; other site 413999011495 PS00190 Cytochrome c family heme-binding site signature. 413999011496 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 413999011497 hypothetical protein; Validated; Region: PRK07080 413999011498 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999011499 Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091 413999011500 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 413999011501 Pfam match to entry PF01648 ACPS,4'-phosphopantetheinyl transferase superfamily, score 25.3, E-value 1.4e-05 413999011502 ornithine carbamoyltransferase; Provisional; Region: PRK04284 413999011503 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 413999011504 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 413999011505 Pfam match to entry PF00185 OTCace,Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain, score 295.6, E-value 6.4e-86 413999011506 Pfam match to entry PF02729 OTCace_N,Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain, score 283.3, E-value 3.2e-82 413999011507 PS00097 Aspartate and ornithine carbamoyltransferases signature. 413999011508 AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235 413999011509 carbamate kinase; Reviewed; Region: PRK12686 413999011510 putative substrate binding site [chemical binding]; other site 413999011511 nucleotide binding site [chemical binding]; other site 413999011512 nucleotide binding site [chemical binding]; other site 413999011513 homodimer interface [polypeptide binding]; other site 413999011514 Pfam match to entry PF00696 aakinase, Amino acid kinase, score 295.1, E-value 9.2e-86 413999011515 serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011 413999011516 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 413999011517 dimer interface [polypeptide binding]; other site 413999011518 active site 413999011519 glycine-pyridoxal phosphate binding site [chemical binding]; other site 413999011520 folate binding site [chemical binding]; other site 413999011521 Pfam match to entry PF00464 SHMT, Serine hydroxymethyltransferase, score 862.4, E-value 1.5e-256 413999011522 PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 413999011523 Uncharacterized conserved protein [Function unknown]; Region: COG2966 413999011524 Protein of unknown function (DUF1212); Region: DUF1212; pfam06738 413999011525 5 probable transmembrane helices predicted for CBO2596 by TMHMM2.0 at aa 83-105, 110-132, 139-161,165-187 and 200-222 413999011526 Protein of unknown function (DUF3815); Region: DUF3815; pfam12821 413999011527 4 probable transmembrane helices predicted for CBO2597 by TMHMM2.0 at aa 2-21, 36-58, 78-97 and 117-139 413999011528 Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148 413999011529 putative homodimer interface [polypeptide binding]; other site 413999011530 putative homotetramer interface [polypeptide binding]; other site 413999011531 putative allosteric switch controlling residues; other site 413999011532 putative metal binding site [ion binding]; other site 413999011533 putative homodimer-homodimer interface [polypeptide binding]; other site 413999011534 Pfam match to entry PF02583 DUF156, Uncharacterised BCR, COG1937, score 50.4, E-value 4.1e-12 413999011535 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999011536 haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282 413999011537 active site 413999011538 motif I; other site 413999011539 motif II; other site 413999011540 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 413999011541 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 35.6, E-value 1.2e-07 413999011542 PS01228 Hypothetical cof family signature 1. 413999011543 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999011544 nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071 413999011545 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 413999011546 active site 413999011547 nucleotide binding site [chemical binding]; other site 413999011548 HIGH motif; other site 413999011549 KMSKS motif; other site 413999011550 Pfam match to entry PF01467 CTP_transf_2,Cytidylyltransferase, score 49.1, E-value 1e-11 413999011551 Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039 413999011552 NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195 413999011553 NAD(P) binding site [chemical binding]; other site 413999011554 substrate binding site [chemical binding]; other site 413999011555 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 413999011556 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999011557 Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613 413999011558 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 413999011559 active site 413999011560 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 413999011561 M18 Peptidase Aminopeptidase I; Region: M18_API; cd05659 413999011562 Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127 413999011563 oligomer interface [polypeptide binding]; other site 413999011564 putative active site [active] 413999011565 metal binding site [ion binding]; metal-binding site 413999011566 Pfam match to entry PF02127 Peptidase_M18,Aminopeptidase I zinc metalloprotease (M18), score 384.1,E-value 1.5e-112 413999011567 Thermotoga maritima CorA-like family; Region: TmCorA-like; cd12822 413999011568 CorA-like Mg2+ transporter protein; Region: CorA; pfam01544 413999011569 oligomer interface [polypeptide binding]; other site 413999011570 metal binding site [ion binding]; metal-binding site 413999011571 metal binding site [ion binding]; metal-binding site 413999011572 putative Cl binding site [ion binding]; other site 413999011573 aspartate ring; other site 413999011574 basic sphincter; other site 413999011575 hydrophobic gate; other site 413999011576 periplasmic entrance; other site 413999011577 Pfam match to entry PF01544 CorA, CorA-like Mg2+ transporter protein, score 84.2, E-value 2.8e-22 413999011578 2 probable transmembrane helices predicted for CBO2606 by TMHMM2.0 at aa 253-275 and 285-307 413999011579 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011580 5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812 413999011581 5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727 413999011582 Pfam match to entry PF01812 5-FTHF_cyc-lig,5-formyltetrahydrofolate cyclo-ligase, score 144.3,E-value 2.2e-40 413999011583 HPr kinase/phosphorylase; Provisional; Region: PRK05428 413999011584 HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603 413999011585 HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918 413999011586 Hpr binding site; other site 413999011587 active site 413999011588 homohexamer subunit interaction site [polypeptide binding]; other site 413999011589 Pfam match to entry PF02603 Hpr_kinase, HPr Serine kinase, score 331.4, E-value 1e-96 413999011590 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011591 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4224 413999011592 Pfam match to entry PF05979 DUF896, Bacterial protein of unknown function (DUF896), score 47.4, E-value 3.3e-11 413999011593 Uncharacterized conserved protein [Function unknown]; Region: COG0398 413999011594 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 413999011595 6 probable transmembrane helices predicted for CBO2610 by TMHMM2.0 at aa 7-29, 61-83, 90-112, 143-165,170-192 and 202-219 413999011596 Pfam match to entry PF00597 DedA, DedA family,score 23.1, E-value 3.6e-06 413999011597 Uncharacterized conserved protein [Function unknown]; Region: COG0398 413999011598 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 413999011599 6 probable transmembrane helices predicted for CBO2611 by TMHMM2.0 at aa 10-29, 42-64, 84-106, 130-152,162-180 and 192-209 413999011600 Pfam match to entry PF00597 DedA, DedA family,score 30.9, E-value 3.1e-06 413999011601 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 413999011602 Cysteine-rich domain; Region: CCG; pfam02754 413999011603 Cysteine-rich domain; Region: CCG; pfam02754 413999011604 Pfam match to entry PF02754 CCG, Cysteine-rich domain, score 32.4, E-value 1.1e-06 413999011605 PS00037 Myb DNA-binding domain repeat signature 1. 413999011606 Pfam match to entry PF02754 CCG, Cysteine-rich domain, score 17.0, E-value 0.0033 413999011607 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999011608 Phosphotransferase enzyme family; Region: APH; pfam01636 413999011609 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 413999011610 active site 413999011611 ATP binding site [chemical binding]; other site 413999011612 transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282 413999011613 GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Region: GT_2_like_a; cd02522 413999011614 transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283 413999011615 Probable Catalytic site; other site 413999011616 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 88.8, E-value 1.1e-23 413999011617 Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897 413999011618 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 413999011619 active site residue [active] 413999011620 Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449 413999011621 active site residue [active] 413999011622 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999011623 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 68.7, E-value 1.3e-17 413999011624 PS00380 Rhodanese signature 1. 413999011625 Pfam match to entry PF00581 Rhodanese,Rhodanese-like domain, score 89.3, E-value 8.2e-24 413999011626 Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320 413999011627 Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516 413999011628 putative active site [active] 413999011629 Pfam match to entry PF03320 FBPase_glpX, Bacterial fructose-1,6-bisphosphatase, glpX-encoded, score 532.7,E-value 2.8e-157 413999011630 Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388 413999011631 Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426 413999011632 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999011633 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 413999011634 Pfam match to entry PF00258 flavodoxin, Flavodoxin,score 28.2, E-value 5.7e-06 413999011635 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 100.0, E-value 5e-27 413999011636 5 probable transmembrane helices predicted for CBO2620 by TMHMM2.0 at aa 7-29, 44-66, 73-92, 102-121 and 128-150 413999011637 Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156 413999011638 active site 413999011639 Pfam match to entry PF01156 IU_nuc_hydro,Inosine-uridine preferring nucleoside hydrolase, score -38.8, E-value 1.2e-08 413999011640 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 413999011641 active site 413999011642 catalytic residues [active] 413999011643 metal binding site [ion binding]; metal-binding site 413999011644 Pfam match to entry PF01327 Pep_deformylase,Polypeptide deformylase, score 151.4, E-value 1.7e-42 413999011645 V-type ATP synthase subunit D; Reviewed; Region: PRK00373 413999011646 Pfam match to entry PF01813 ATP-synt_D, ATP synthase subunit D, score 241.2, E-value 1.5e-69 413999011647 V-type ATP synthase subunit B; Provisional; Region: PRK04196 413999011648 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 413999011649 V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135 413999011650 Walker A motif homologous position; other site 413999011651 Walker B motif; other site 413999011652 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 413999011653 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain, score 83.3,E-value 5.1e-22 413999011654 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain,score 299.4, E-value 4.5e-87 413999011655 PS00152 ATP synthase alpha and beta subunits signature. 413999011656 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain, score 47.0, E-value 4.3e-11 413999011657 V-type ATP synthase subunit A; Provisional; Region: PRK04192 413999011658 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 413999011659 V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134 413999011660 Walker A motif/ATP binding site; other site 413999011661 Walker B motif; other site 413999011662 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 413999011663 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain, score 118.6,E-value 1.2e-32 413999011664 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain,score 314.8, E-value 1.1e-91 413999011665 PS00152 ATP synthase alpha and beta subunits signature. 413999011666 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011667 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain, score 72.8, E-value 7.4e-19 413999011668 V-type ATP synthase subunit F; Provisional; Region: PRK01395 413999011669 V-type ATP synthase subunit C; Provisional; Region: PRK01198 413999011670 Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527 413999011671 Pfam match to entry PF01992 vATP-synt_AC39, ATP synthase (C/AC39) subunit, score 63.1, E-value 6.2e-16 413999011672 Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; Region: NtpE; COG1390 413999011673 V-type ATP synthase subunit E; Provisional; Region: PRK03963; cl17074 413999011674 Pfam match to entry PF01991 vATP-synt_E, ATP synthase (E/31 kDa) subunit, score 36.8, E-value 5.2e-08 413999011675 V-type ATP synthase subunit K; Validated; Region: PRK06558 413999011676 ATP synthase subunit C; Region: ATP-synt_C; pfam00137 413999011677 ATP synthase subunit C; Region: ATP-synt_C; pfam00137 413999011678 Pfam match to entry PF00137 ATP-synt_C, ATP synthase subunit C, score 36.9, E-value 4.8e-08 413999011679 4 probable transmembrane helices predicted for CBO2628 by TMHMM2.0 at aa 13-35, 59-81, 93-115 and 135-157 413999011680 Pfam match to entry PF00137 ATP-synt_C, ATP synthase subunit C, score 47.8, E-value 2.6e-11 413999011681 V-type ATP synthase subunit I; Validated; Region: PRK05771 413999011682 Pfam match to entry PF01496 V_ATPase_sub_a, V-type ATPase 116kDa subunit family, score 155.3, E-value 1.1e-43 413999011683 7 probable transmembrane helices predicted for CBO2629 by TMHMM2.0 at aa 369-391, 412-434, 449-471,484-506, 537-559, 564-586 and 591-613 413999011684 B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068 413999011685 Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729 413999011686 Protein of unknown function (DUF4080); Region: DUF4080; pfam13311 413999011687 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 82.2, E-value 1.1e-21 413999011688 Pfam match to entry PF02310 B12-binding, B12 binding domain, score 64.6, E-value 2.2e-16 413999011689 Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009 413999011690 Zn binding site [ion binding]; other site 413999011691 Pfam match to entry PF00882 Zn_dep_PLPC, Zinc dependent phospholipase C, score -85.2, E-value 8.1e-05 413999011692 Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133 413999011693 1 probable transmembrane helix predicted for CBO2633 by TMHMM2.0 at aa 7-26 413999011694 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 413999011695 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474 413999011696 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999011697 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 413999011698 Soluble P-type ATPase [General function prediction only]; Region: COG4087 413999011699 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 413999011700 Pfam match to entry PF00689 Cation_ATPase_C, Cation transporting ATPase, C-terminus, score 90.6, E-value 3.3e-24 413999011701 8 probable transmembrane helices predicted for CBO2634 by TMHMM2.0 at aa 40-62, 67-85, 219-241, 256-278,650-672, 727-749, 790-812 and 822-844 413999011702 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 75.7, E-value 1e-19 413999011703 PS00154 E1-E2 ATPases phosphorylation site. 413999011704 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 337.1, E-value 2e-98 413999011705 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus, score 84.6, E-value 2.1e-22 413999011706 putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK14869 413999011707 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 413999011708 DRTGG domain; Region: DRTGG; pfam07085 413999011709 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 413999011710 DHH family; Region: DHH; pfam01368 413999011711 DHHA2 domain; Region: DHHA2; pfam02833 413999011712 Pfam match to entry PF00571 CBS, CBS domain, score 29.5, E-value 7.9e-06 413999011713 PS00037 Myb DNA-binding domain repeat signature 1. 413999011714 Pfam match to entry PF00571 CBS, CBS domain, score 38.4, E-value 1.7e-08 413999011715 Pfam match to entry PF01368 DHH, DHH family, score 24.3, E-value 2.7e-05 413999011716 Pfam match to entry PF02833 DHHA2, DHHA2 domain,score 91.5, E-value 1.7e-24 413999011717 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011718 flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12817 413999011719 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 413999011720 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 413999011721 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein, score 54.2, E-value 2.9e-13 413999011722 PS00588 Flagella basal body rod proteins signature. 413999011723 flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12818 413999011724 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 413999011725 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 413999011726 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein, score 49.6, E-value 7e-12 413999011727 PS00588 Flagella basal body rod proteins signature. 413999011728 RNA polymerase sigma factor, FliA/WhiG family; Region: FliA_WhiG; TIGR02479 413999011729 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999011730 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 413999011731 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999011732 DNA binding residues [nucleotide binding] 413999011733 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 75.0, E-value 1.7e-19 413999011734 PS00716 Sigma-70 factors family signature 2. 413999011735 Predicted helix-turn-helix motif with score 1890.000, SD 5.62 at aa 205-226, sequence LTLKEIGKILNVSESRVCQLHS 413999011736 Predicted helix-turn-helix motif with score 1890.000, SD 5.62 at aa 113-134, sequence PNLIQIADELNISLKEVSEIEN 413999011737 Pfam match to entry PF04539 sigma70_r3, Sigma-70 region 3, score 24.0, E-value 5.6e-06 413999011738 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 65.4, E-value 1.3e-16 413999011739 PS00715 Sigma-70 factors family signature 1. 413999011740 Flagellar protein YcgR; Region: YcgR_2; pfam12945 413999011741 PilZ domain; Region: PilZ; pfam07238 413999011742 Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455 413999011743 FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038 413999011744 P-loop; other site 413999011745 Pfam match to entry PF00991 ParA, ParA family ATPase, score 33.6, E-value 4.6e-07 413999011746 PS00043 Bacterial regulatory proteins, gntR family signature. 413999011747 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011748 flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703 413999011749 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999011750 Pfam match to entry PF00448 SRP54, SRP54-type protein, GTPase domain, score 115.8, E-value 8.5e-32 413999011751 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011752 flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012 413999011753 FHIPEP family; Region: FHIPEP; pfam00771 413999011754 Pfam match to entry PF00771 FHIPEP, FHIPEP family,score 1104.9, E-value 0 413999011755 5 probable transmembrane helices predicted for CBO2645 by TMHMM2.0 at aa 16-38, 48-82, 103-125, 198-220 and 286-308 413999011756 PS00994 Bacterial export FHIPEP family signature. 413999011757 bifunctional flagellar biosynthesis protein FliR/FlhB; Provisional; Region: PRK12772 413999011758 Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684 413999011759 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257 413999011760 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family, score 456.5, E-value 2.4e-134 413999011761 10 probable transmembrane helices predicted for CBO2646 by TMHMM2.0 at aa 5-27, 32-54, 67-89, 125-147,168-190, 210-232, 289-311, 350-372, 393-415 and 441-463 413999011762 Pfam match to entry PF01311 Bac_export_1, Bacterial export proteins, family 1, score 103.2, E-value 5.2e-28 413999011763 Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliQ; COG1987 413999011764 Pfam match to entry PF01313 Bac_export_3, Bacterial export proteins, family 3, score 98.4, E-value 1.5e-26 413999011765 2 probable transmembrane helices predicted for CBO2647 by TMHMM2.0 at aa 13-35 and 55-77 413999011766 flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699 413999011767 Pfam match to entry PF00813 FliP, FliP family,score 392.5, E-value 4.5e-115 413999011768 5 probable transmembrane helices predicted for CBO2648 by TMHMM2.0 at aa 10-29, 58-80, 100-122, 199-221 and 231-250 413999011769 PS01061 Flagella transport protein fliP family signature 2. 413999011770 PS01060 Flagella transport protein fliP family signature 1. 413999011771 flagellar biosynthetic protein FliO; Region: FliO_TIGR; TIGR03500 413999011772 PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 413999011773 1 probable transmembrane helix predicted for CBO2649 by TMHMM2.0 at aa 5-27 413999011774 Flagellar basal body-associated protein FliL; Region: FliL; pfam03748 413999011775 Pfam match to entry PF03748 FliL, Flagellar basal body-associated protein FliL, score 95.0, E-value 1.6e-25 413999011776 1 probable transmembrane helix predicted for CBO2650 by TMHMM2.0 at aa 15-37 413999011777 flagellar motor protein MotS; Reviewed; Region: PRK06925 413999011778 Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677 413999011779 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 413999011780 ligand binding site [chemical binding]; other site 413999011781 Pfam match to entry PF00691 OmpA, OmpA family,score 121.4, E-value 1.8e-33 413999011782 1 probable transmembrane helix predicted for CBO2651 by TMHMM2.0 at aa 20-42 413999011783 Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291 413999011784 MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568 413999011785 Pfam match to entry PF01618 MotA_ExbB,MotA/TolQ/ExbB proton channel family, score 40.0, E-value 1.2e-09 413999011786 4 probable transmembrane helices predicted for CBO2652 by TMHMM2.0 at aa 7-24, 34-56, 151-173 and 188-210 413999011787 PS01307 Flagellar motor protein motA family signature. 413999011788 Flagellar protein (FlbD); Region: FlbD; pfam06289 413999011789 Pfam match to entry PF06289 FlbD, Flagellar protein (FlbD), score 96.6, E-value 5.1e-26 413999011790 flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12636 413999011791 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 413999011792 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 413999011793 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011794 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011795 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein, score 53.6, E-value 4.4e-13 413999011796 PS00588 Flagella basal body rod proteins signature. 413999011797 Protein of unknown function (DUF3766); Region: DUF3766; cl11797 413999011798 Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963 413999011799 Pfam match to entry PF03963 FlgD, Flagellar hook capping protein, score 65.2, E-value 1.5e-16 413999011800 Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120 413999011801 Pfam match to entry PF02120 Flg_hook, Flagellar hook-length control protein, score 79.9, E-value 5.5e-21 413999011802 flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK07720 413999011803 Flagellar FliJ protein; Region: FliJ; pfam02050 413999011804 flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497 413999011805 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 413999011806 Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136 413999011807 Walker A motif/ATP binding site; other site 413999011808 Walker B motif; other site 413999011809 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain,score 375.4, E-value 5.9e-110 413999011810 PS00152 ATP synthase alpha and beta subunits signature. 413999011811 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011812 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain, score 34.9, E-value 1.9e-07 413999011813 Flagellar assembly protein FliH; Region: FliH; pfam02108 413999011814 flagellar motor switch protein G; Validated; Region: fliG; PRK05686 413999011815 FliG C-terminal domain; Region: FliG_C; pfam01706 413999011816 Pfam match to entry PF01706 FliG-C, FliG C-terminal domain, score 176.5, E-value 4.7e-50 413999011817 flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007 413999011818 Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907 413999011819 Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345 413999011820 2 probable transmembrane helices predicted for CBO2662 by TMHMM2.0 at aa 24-46 and 429-451 413999011821 Pfam match to entry PF01514 YscJ_FliF, Secretory protein of YscJ/FliF family, score 150.6, E-value 2.9e-42 413999011822 flagellar hook-basal body protein FliE; Provisional; Region: fliE; PRK12728 413999011823 Pfam match to entry PF02049 FliE, Flagellar hook-basal body complex protein FliE, score 92.5, E-value 8.8e-25 413999011824 flagellar basal body rod protein FlgC; Provisional; Region: flgC; PRK12630 413999011825 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 413999011826 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 413999011827 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein, score 33.1, E-value 6.9e-07 413999011828 flagellar basal body rod protein FlgB; Provisional; Region: flgB; PRK12623 413999011829 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein, score 24.8, E-value 1.1e-05 413999011830 flagellin; Provisional; Region: PRK12804 413999011831 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999011832 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 413999011833 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus, score 41.8, E-value 1.7e-09 413999011834 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 142.7, E-value 6.6e-40 413999011835 argininosuccinate lyase; Provisional; Region: PRK00855 413999011836 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 413999011837 active sites [active] 413999011838 tetramer interface [polypeptide binding]; other site 413999011839 Pfam match to entry PF00206 lyase_1, Lyase, score 286.5, E-value 3.6e-83 413999011840 PS00163 Fumarate lyases signature. 413999011841 argininosuccinate synthase; Provisional; Region: PRK13820 413999011842 Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In...; Region: Argininosuccinate_Synthase; cd01999 413999011843 ANP binding site [chemical binding]; other site 413999011844 Substrate Binding Site II [chemical binding]; other site 413999011845 Substrate Binding Site I [chemical binding]; other site 413999011846 Pfam match to entry PF00764 Arginosuc_synth,Arginosuccinate synthase, score 691.6, E-value 3.9e-205 413999011847 PS00565 Argininosuccinate synthase signature 2. 413999011848 PS00564 Argininosuccinate synthase signature 1. 413999011849 cardiolipin synthetase; Reviewed; Region: cls; PRK01642 413999011850 Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110 413999011851 putative active site [active] 413999011852 catalytic site [active] 413999011853 catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112 413999011854 putative active site [active] 413999011855 catalytic site [active] 413999011856 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif, score 26.8, E-value 5.2e-05 413999011857 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif, score 37.3, E-value 3.8e-08 413999011858 2 probable transmembrane helices predicted for CBO2674 by TMHMM2.0 at aa 4-26 and 33-55 413999011859 Predicted membrane protein [Function unknown]; Region: COG4129 413999011860 Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081 413999011861 Pfam match to entry PF06081 DUF939, Bacterial protein of unknown function (DUF939), score 77.0, E-value 8e-22 413999011862 4 probable transmembrane helices predicted for CBO2675 by TMHMM2.0 at aa 13-35, 71-93, 100-122 and 127-144 413999011863 Predicted integral membrane protein [Function unknown]; Region: COG5652 413999011864 Pfam match to entry PF04892 VanZ, VanZ like family,score 40.0, E-value 5.6e-09 413999011865 4 probable transmembrane helices predicted for CBO2677 by TMHMM2.0 at aa 7-24, 60-82, 95-112 and 122-141 413999011866 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 413999011867 This locus is possibly involved in the biosynthesis of a capsular polysaccharide 413999011868 13 probable transmembrane helices predicted for CBO2678 by TMHMM2.0 at aa 16-33, 46-68, 89-111, 124-146,153-172, 177-199, 212-234, 249-271, 302-324, 334-356,363-385, 389-411 and 432-454 413999011869 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 19.0, E-value 1.7e-05 413999011870 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999011871 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 413999011872 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999011873 NAD(P) binding site [chemical binding]; other site 413999011874 active site 413999011875 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase, score 287.8,E-value 1.4e-83 413999011876 N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569 413999011877 NeuB family; Region: NeuB; pfam03102 413999011878 C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615 413999011879 NeuB binding interface [polypeptide binding]; other site 413999011880 putative substrate binding site [chemical binding]; other site 413999011881 Pfam match to entry PF01354 Antifreeze,Antifreeze-like domain, score 76.1, E-value 7.5e-20 413999011882 Pfam match to entry PF03102 NeuB, NeuB family,score 266.3, E-value 4.1e-77 413999011883 CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513 413999011884 ligand binding site; other site 413999011885 tetramer interface; other site 413999011886 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980 413999011887 Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369 413999011888 Pfam match to entry PF02348 CTP_transf_3,Cytidylyltransferase, score 61.3, E-value 2.2e-15 413999011889 10 probable transmembrane helices predicted for CBO2682 by TMHMM2.0 at aa 7-24, 28-50, 63-94, 109-131,138-160, 170-192, 213-232, 311-330, 343-360 and 364-381 413999011890 Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922 413999011891 Pfam match to entry PF05855 LST,Lipooligosaccharide sialyltransferase (LST), score 45.0,E-value 1.2e-12 413999011892 Domain of unknown function (DUF4422); Region: DUF4422; pfam14393 413999011893 UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562 413999011894 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999011895 UDP-galactopyranose mutase; Region: GLF; pfam03275 413999011896 Pfam match to entry PF03275 GLF,UDP-galactopyranose mutase, score 416.2, E-value 3.2e-122 413999011897 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025 413999011898 Bacterial sugar transferase; Region: Bac_transf; pfam02397 413999011899 Pfam match to entry PF02397 Bact_transf, Bacterial sugar transferase, score 272.9, E-value 4.3e-79 413999011900 1 probable transmembrane helix predicted for CBO2686 by TMHMM2.0 at aa 36-57 413999011901 capsular exopolysaccharide family; Region: eps_fam; TIGR01007 413999011902 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 413999011903 Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464 413999011904 Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944 413999011905 Chain length determinant protein; Region: Wzz; cl15801 413999011906 2 probable transmembrane helices predicted for CBO2689 by TMHMM2.0 at aa 24-46 and 178-195 413999011907 Pfam match to entry PF02706 wzz, Chain length determinant protein, score 75.8, E-value 9.2e-20 413999011908 PS00017 ATP/GTP-binding site motif A (P-loop). 413999011909 Transcriptional regulator [Transcription]; Region: LytR; COG1316 413999011910 Pfam match to entry PF03816 LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain, score 203.4, E-value 3.6e-58 413999011911 1 probable transmembrane helix predicted for CBO2690 by TMHMM2.0 at aa 7-29 413999011912 Putative motility protein; Region: YjfB_motility; pfam14070 413999011913 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999011914 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999011915 dimer interface [polypeptide binding]; other site 413999011916 putative CheW interface [polypeptide binding]; other site 413999011917 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 27.7, E-value 4.2e-09 413999011918 flagellin; Provisional; Region: PRK12804 413999011919 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999011920 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 413999011921 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus, score 24.7, E-value 5e-05 413999011922 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 165.1, E-value 1.3e-46 413999011923 1 probable transmembrane helix predicted for CBO2696 by TMHMM2.0 at aa 10-27 413999011924 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 413999011925 binding surface 413999011926 TPR motif; other site 413999011927 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053 413999011928 catalytic triad [active] 413999011929 pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590 413999011930 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229 413999011931 active site 413999011932 catalytic triad [active] 413999011933 oxyanion hole [active] 413999011934 Pfam match to entry PF00657 Lipase_GDSL, GDSL-like Lipase/Acylhydrolase, score 21.4, E-value 4e-05 413999011935 D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092 413999011936 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 413999011937 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 413999011938 active site 413999011939 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999011940 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999011941 binding surface 413999011942 TPR motif; other site 413999011943 Pfam match to entry PF00515 TPR, TPR Domain, score 26.5, E-value 6.6e-05 413999011944 Pfam match to entry PF00515 TPR, TPR Domain, score 20.7, E-value 0.0036 413999011945 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 134.5, E-value 2e-37 413999011946 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 413999011947 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999011948 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 42.9, E-value 7.3e-10 413999011949 1 probable transmembrane helix predicted for CBO2704 by TMHMM2.0 at aa 144-166 413999011950 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 413999011951 glycosyltransferase, GG-Bacteroidales peptide system; Region: glyco_rSAM_CFB; TIGR04157 413999011952 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 65.6, E-value 1.1e-16 413999011953 Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319 413999011954 Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide; Region: AANH_like; cl00292 413999011955 Ligand Binding Site [chemical binding]; other site 413999011956 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 413999011957 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 413999011958 Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u7; cd10931 413999011959 putative active site [active] 413999011960 putative catalytic site [active] 413999011961 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999011962 S-adenosylmethionine binding site [chemical binding]; other site 413999011963 This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794 413999011964 glycosyltransferase, GG-Bacteroidales peptide system; Region: glyco_rSAM_CFB; TIGR04157 413999011965 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 68.8, E-value 1.2e-17 413999011966 Radical SAM superfamily; Region: Radical_SAM; pfam04055 413999011967 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999011968 FeS/SAM binding site; other site 413999011969 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 34.5, E-value 2.5e-07 413999011970 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999011971 Cephalosporin hydroxylase; Region: CmcI; pfam04989 413999011972 Pfam match to entry PF04989 CmcI, Cephalosporin hydroxylase, score 135.5, E-value 9.8e-38 413999011973 Methyltransferase domain; Region: Methyltransf_23; pfam13489 413999011974 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999011975 S-adenosylmethionine binding site [chemical binding]; other site 413999011976 C-methyltransferase C-terminal domain; Region: Methyltransf_14; pfam08484 413999011977 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999011978 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 413999011979 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999011980 NAD(P) binding site [chemical binding]; other site 413999011981 active site 413999011982 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase, score 25.0,E-value 6.4e-14 413999011983 dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908 413999011984 Pfam match to entry PF00908 dTDP_sugar_isom,dTDP-4-dehydrorhamnose 3,5-epimerase, score 290.4, E-value 2.4e-84 413999011985 Putative zinc binding domain; Region: Methyltransf_13; pfam08421 413999011986 Methyltransferase domain; Region: Methyltransf_23; pfam13489 413999011987 Methyltransferase domain; Region: Methyltransf_12; pfam08242 413999011988 C-methyltransferase C-terminal domain; Region: Methyltransf_14; pfam08484 413999011989 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999011990 Radical SAM superfamily; Region: Radical_SAM; pfam04055 413999011991 FeS/SAM binding site; other site 413999011992 DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974 413999011993 Domain of unknown function (DUF4008); Region: DUF4008; pfam13186 413999011994 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 60.5, E-value 3.8e-15 413999011995 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208 413999011996 G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524 413999011997 substrate binding site; other site 413999011998 Pfam match to entry PF00483 NTP_transferase,Nucleotidyl transferase, score -5.1, E-value 6.6e-10 413999011999 pseudaminic acid synthase; Region: PseI; TIGR03586 413999012000 NeuB family; Region: NeuB; pfam03102 413999012001 C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615 413999012002 NeuB binding interface [polypeptide binding]; other site 413999012003 putative substrate binding site [chemical binding]; other site 413999012004 Pfam match to entry PF01354 Antifreeze,Antifreeze-like domain, score 86.4, E-value 6e-23 413999012005 Pfam match to entry PF03102 NeuB, NeuB family,score 404.7, E-value 9.4e-119 413999012006 SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat; Region: GT2_SpsF; cd02518 413999012007 ligand binding site; other site 413999012008 Pfam match to entry PF02348 CTP_transf_3,Cytidylyltransferase, score 124.6, E-value 2e-34 413999012009 Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011 413999012010 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999012011 motif II; other site 413999012012 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 83.1, E-value 6e-22 413999012013 carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767 413999012014 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 413999012015 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 413999012016 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999012017 NAD(P) binding site [chemical binding]; other site 413999012018 active site 413999012019 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase, score 196.0,E-value 6.3e-56 413999012020 Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719 413999012021 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 413999012022 NAD(P) binding site [chemical binding]; other site 413999012023 homodimer interface [polypeptide binding]; other site 413999012024 substrate binding site [chemical binding]; other site 413999012025 active site 413999012026 Pfam match to entry PF02719 Polysacc_synt_2,Polysaccharide biosynthesis protein, score -147.3, E-value 1.9e-14 413999012027 UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511 413999012028 putative metal binding site; other site 413999012029 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 413999012030 TPR motif; other site 413999012031 binding surface 413999012032 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999012033 TPR motif; other site 413999012034 binding surface 413999012035 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999012036 binding surface 413999012037 TPR motif; other site 413999012038 Pfam match to entry PF00515 TPR, TPR Domain, score 15.7, E-value 0.051 413999012039 Pfam match to entry PF00515 TPR, TPR Domain, score 2.8, E-value 1.7 413999012040 Pfam match to entry PF00515 TPR, TPR Domain, score 3.0, E-value 1.6 413999012041 Pfam match to entry PF00515 TPR, TPR Domain, score 8.4, E-value 0.37 413999012042 Pfam match to entry PF00515 TPR, TPR Domain, score 17.7, E-value 0.028 413999012043 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 68.7, E-value 1.3e-17 413999012044 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604 413999012045 Pfam match to entry PF01973 DUF115, Protein of unknown function DUF115, score 157.2, E-value 2.9e-44 413999012046 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 413999012047 UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511 413999012048 putative metal binding site; other site 413999012049 TPR repeat; Region: TPR_11; pfam13414 413999012050 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999012051 binding surface 413999012052 TPR motif; other site 413999012053 Tetratricopeptide repeat; Region: TPR_16; pfam13432 413999012054 Pfam match to entry PF00515 TPR, TPR Domain, score 1.4, E-value 2.5 413999012055 Pfam match to entry PF00515 TPR, TPR Domain, score 10.6, E-value 0.21 413999012056 Pfam match to entry PF00515 TPR, TPR Domain, score 6.8, E-value 0.59 413999012057 Pfam match to entry PF00515 TPR, TPR Domain, score 9.4, E-value 0.29 413999012058 Pfam match to entry PF00535 Glycos_transf_2,Glycosyl transferase, score 58.7, E-value 1.3e-14 413999012059 PS00141 Eukaryotic and viral aspartyl proteases active site. 413999012060 flagellin; Provisional; Region: PRK12804 413999012061 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999012062 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 413999012063 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus, score 127.0, E-value 3.5e-35 413999012064 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 252.3, E-value 6.9e-73 413999012065 flagellin; Provisional; Region: PRK12804 413999012066 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999012067 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 413999012068 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus, score 127.0, E-value 3.5e-35 413999012069 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 252.4, E-value 6.3e-73 413999012070 Flagellar protein FliT; Region: FliT; pfam05400 413999012071 Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465 413999012072 Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195 413999012073 Pfam match to entry PF02465 FliD, Flagellar hook-associated protein 2, score -4.0, E-value 1.7e-10 413999012074 Flagellin-specific chaperone FliS [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliS; COG1516 413999012075 Pfam match to entry PF02561 FliS, Flagellar protein FliS, score 109.6, E-value 6.4e-30 413999012076 FlaG protein; Region: FlaG; pfam03646 413999012077 Pfam match to entry PF03646 FlaG, FlaG protein,score 48.4, E-value 1.7e-11 413999012078 carbon storage regulator; Provisional; Region: PRK01712 413999012079 Pfam match to entry PF02599 CsrA, Global regulator protein family, score 95.1, E-value 1.5e-25 413999012080 flagellar assembly protein FliW; Provisional; Region: PRK13285 413999012081 Pfam match to entry PF02623 DUF180, Uncharacterized BCR, COG1699, score 111.9, E-value 1.3e-30 413999012082 flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701 413999012083 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 413999012084 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 413999012085 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus, score 14.4, E-value 0.0022 413999012086 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, score 20.6, E-value 5.9e-06 413999012087 Flagellar hook-associated protein [Cell motility and secretion]; Region: FlgK; COG1256 413999012088 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 413999012089 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 413999012090 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein, score 40.6, E-value 3.8e-09 413999012091 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012092 FlgN protein; Region: FlgN; pfam05130 413999012093 Pfam match to entry PF05130 FlgN, FlgN protein,score -8.8, E-value 0.0024 413999012094 Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316 413999012095 Pfam match to entry PF04316 FlgM, Anti-sigma-28 factor, FlgM, score 42.5, E-value 9.8e-10 413999012096 flagellar motor switch protein; Validated; Region: PRK08119 413999012097 CheC-like family; Region: CheC; pfam04509 413999012098 CheC-like family; Region: CheC; pfam04509 413999012099 Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886 413999012100 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein, score 111.6,E-value 1.6e-30 413999012101 Pfam match to entry PF04509 CheC, CheC-like family,score 48.5, E-value 1.5e-11 413999012102 Pfam match to entry PF04509 CheC, CheC-like family,score 58.7, E-value 1.3e-14 413999012103 flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666 413999012104 Surface presentation of antigens (SPOA); Region: SpoA; pfam01052 413999012105 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein, score 45.4,E-value 1.3e-10 413999012106 Pfam match to entry PF02154 FliM, Flagellar motor switch protein FliM, score 246.9, E-value 3e-71 413999012107 Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835 413999012108 Pfam match to entry PF01584 CheW, CheW-like domain,score 85.3, E-value 1.3e-22 413999012109 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 413999012110 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999012111 active site 413999012112 phosphorylation site [posttranslational modification] 413999012113 intermolecular recognition site; other site 413999012114 dimerization interface [polypeptide binding]; other site 413999012115 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 154.3, E-value 2.2e-43 413999012116 Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776 413999012117 CheC-like family; Region: CheC; pfam04509 413999012118 CheC-like family; Region: CheC; pfam04509 413999012119 Pfam match to entry PF04509 CheC, CheC-like family,score 48.2, E-value 2e-11 413999012120 Pfam match to entry PF04509 CheC, CheC-like family,score 67.5, E-value 3e-17 413999012121 Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643 413999012122 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 413999012123 putative binding surface; other site 413999012124 active site 413999012125 P2 response regulator binding domain; Region: P2; pfam07194 413999012126 Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895 413999012127 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999012128 ATP binding site [chemical binding]; other site 413999012129 Mg2+ binding site [ion binding]; other site 413999012130 G-X-G motif; other site 413999012131 CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731 413999012132 Pfam match to entry PF01584 CheW, CheW-like domain,score 69.0, E-value 1.1e-17 413999012133 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 101.4, E-value 1.8e-27 413999012134 Pfam match to entry PF02895 H-kinase_dim, Signal transducing histidine kinase, homodimeric domain, score 78.4, E-value 1.6e-20 413999012135 Pfam match to entry PF01627 Hpt, Hpt domain, score 147.9, E-value 1.9e-41 413999012136 Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352 413999012137 CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705 413999012138 CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739 413999012139 Pfam match to entry PF01739 CheR, CheR methyltransferase, SAM binding domain, score 249.7,E-value 4.2e-72 413999012140 Pfam match to entry PF03705 CheR_N, CheR methyltransferase, all-alpha domain, score 54.8, E-value 2e-13 413999012141 chemotaxis-specific methylesterase; Provisional; Region: PRK00742 413999012142 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999012143 active site 413999012144 phosphorylation site [posttranslational modification] 413999012145 intermolecular recognition site; other site 413999012146 dimerization interface [polypeptide binding]; other site 413999012147 CheB methylesterase; Region: CheB_methylest; pfam01339 413999012148 Pfam match to entry PF01339 CheB_methylest, CheB methylesterase, score 256.1, E-value 5e-74 413999012149 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 94.6, E-value 2.1e-25 413999012150 chemoreceptor glutamine deamidase CheD; Provisional; Region: PRK13490 413999012151 Pfam match to entry PF03975 CheD, CheD, score 150.6, E-value 2.8e-42 413999012152 Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835 413999012153 Pfam match to entry PF01584 CheW, CheW-like domain,score 114.1, E-value 2.7e-31 413999012154 Protein of unknown function (DUF342); Region: DUF342; pfam03961 413999012155 Pfam match to entry PF03961 DUF342, Protein of unknown function (DUF342), score -56.6, E-value 1.4e-08 413999012156 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999012157 PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255 413999012158 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999012159 active site turn [active] 413999012160 phosphorylation site [posttranslational modification] 413999012161 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 413999012162 HPr interaction site; other site 413999012163 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999012164 active site 413999012165 phosphorylation site [posttranslational modification] 413999012166 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 182.9, E-value 5.4e-52 413999012167 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999012168 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 57.2, E-value 3.6e-14 413999012169 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999012170 9 probable transmembrane helices predicted for CBO2754 by TMHMM2.0 at aa 48-65, 70-92, 123-145, 165-187,216-238, 258-280, 293-310, 325-347 and 368-390 413999012171 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 245.5, E-value 7.7e-71 413999012172 transcriptional antiterminator BglG; Provisional; Region: PRK09772 413999012173 CAT RNA binding domain; Region: CAT_RBD; smart01061 413999012174 PRD domain; Region: PRD; pfam00874 413999012175 PRD domain; Region: PRD; pfam00874 413999012176 Pfam match to entry PF00874 PRD, PRD domain, score 103.5, E-value 4.3e-28 413999012177 Pfam match to entry PF00874 PRD, PRD domain, score 122.5, E-value 8e-34 413999012178 Pfam match to entry PF03123 CAT_RBD, CAT RNA binding domain, score 67.2, E-value 3.7e-17 413999012179 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 413999012180 PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449 413999012181 homodimer interface [polypeptide binding]; other site 413999012182 substrate-cofactor binding pocket; other site 413999012183 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999012184 catalytic residue [active] 413999012185 Pfam match to entry PF01063 aminotran_4,Aminotransferase class IV, score 47.2, E-value 8.7e-13 413999012186 PS00770 Aminotransferases class-IV signature. 413999012187 haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702 413999012188 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999012189 motif II; other site 413999012190 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 18.1, E-value 0.00088 413999012191 Protein of unknown function (DUF1292); Region: DUF1292; pfam06949 413999012192 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176 413999012193 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 413999012194 dimer interface [polypeptide binding]; other site 413999012195 PYR/PP interface [polypeptide binding]; other site 413999012196 TPP binding site [chemical binding]; other site 413999012197 substrate binding site [chemical binding]; other site 413999012198 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014 413999012199 Domain of unknown function; Region: EKR; smart00890 413999012200 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999012201 Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377 413999012202 TPP-binding site [chemical binding]; other site 413999012203 dimer interface [polypeptide binding]; other site 413999012204 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 15.2, E-value 0.001 413999012205 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999012206 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 29.7, E-value 5.2e-06 413999012207 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999012208 Pfam match to entry PF01558 POR, Pyruvate ferredoxin/flavodoxin oxidoreductase, score 269.6, E-value 4.4e-78 413999012209 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999012210 Pfam match to entry PF01855 POR_N, Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain, score 400.5, E-value 1.7e-117 413999012211 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed; Region: PRK12446 413999012212 MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785 413999012213 active site 413999012214 homodimer interface [polypeptide binding]; other site 413999012215 Pfam match to entry PF04101 Glyco_tran_28_C,Glycosyltransferase 28 C-terminal domain, score 114.0, E-value 3e-31 413999012216 Pfam match to entry PF03033 Glyco_transf_28,Glycosyltransferase 28 N-terminal domain, score 167.4, E-value 2.4e-47 413999012217 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999012218 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999012219 dimer interface [polypeptide binding]; other site 413999012220 phosphorylation site [posttranslational modification] 413999012221 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999012222 ATP binding site [chemical binding]; other site 413999012223 Mg2+ binding site [ion binding]; other site 413999012224 G-X-G motif; other site 413999012225 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 134.5, E-value 2e-37 413999012226 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 65.5, E-value 1.2e-16 413999012227 Pfam match to entry PF00785 PAC, PAC motif, score 15.4, E-value 0.0014 413999012228 single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644 413999012229 DHH family; Region: DHH; pfam01368 413999012230 DHHA1 domain; Region: DHHA1; pfam02272 413999012231 Pfam match to entry PF02272 DHHA1, DHHA1 domain,score 47.2, E-value 3.8e-11 413999012232 Pfam match to entry PF01368 DHH, DHH family, score 120.7, E-value 2.9e-33 413999012233 Predicted helix-turn-helix motif with score 1096.000, SD 2.92 at aa 12-33, sequence LNIRDIANKSGISETLCTVLVN 413999012234 Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648 413999012235 AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019 413999012236 AP (apurinic/apyrimidinic) site pocket; other site 413999012237 DNA interaction; other site 413999012238 Metal-binding active site; metal-binding site 413999012239 Pfam match to entry PF01261 AP_endonuc_2, AP endonuclease 2, score 190.5, E-value 2.8e-54 413999012240 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388 413999012241 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 413999012242 Pfam match to entry PF01436 NHL, NHL repeat, score 18.4, E-value 0.018 413999012243 Pfam match to entry PF01436 NHL, NHL repeat, score 25.0, E-value 0.00018 413999012244 Pfam match to entry PF01436 NHL, NHL repeat, score 21.1, E-value 0.0027 413999012245 Pfam match to entry PF01436 NHL, NHL repeat, score 17.4, E-value 0.035 413999012246 Pfam match to entry PF01436 NHL, NHL repeat, score 3.2, E-value 5.5 413999012247 Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612 413999012248 Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675 413999012249 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 413999012250 Pfam match to entry PF05193 Peptidase_M16_C,Peptidase M16 inactive domain, score 103.1, E-value 5.9e-28 413999012251 Pfam match to entry PF00675 Peptidase_M16,Insulinase (Peptidase M16), score 67.4, E-value 3.1e-17 413999012252 Predicted membrane protein [Function unknown]; Region: COG2246 413999012253 GtrA-like protein; Region: GtrA; pfam04138 413999012254 DJ-1 family protein; Region: not_thiJ; TIGR01383 413999012255 Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135 413999012256 conserved cys residue [active] 413999012257 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family, score 139.3, E-value 7.2e-39 413999012258 Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852 413999012259 Pfam match to entry PF04309 G3P_antiterm,Glycerol-3-phosphate responsive antiterminator, score 252.0, E-value 8.5e-73 413999012260 DNA topoisomerase IV subunit A; Provisional; Region: PRK13979 413999012261 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 413999012262 CAP-like domain; other site 413999012263 active site 413999012264 primary dimer interface [polypeptide binding]; other site 413999012265 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 413999012266 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 43.2,E-value 6e-10 413999012267 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 29.9,E-value 6.3e-06 413999012268 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 16.8,E-value 0.033 413999012269 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller, score 25.9,E-value 9.8e-05 413999012270 Pfam match to entry PF00521 DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A, score 833.3, E-value 9e-248 413999012271 DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559 413999012272 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999012273 ATP binding site [chemical binding]; other site 413999012274 Mg2+ binding site [ion binding]; other site 413999012275 G-X-G motif; other site 413999012276 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 413999012277 anchoring element; other site 413999012278 dimer interface [polypeptide binding]; other site 413999012279 ATP binding site [chemical binding]; other site 413999012280 Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718 413999012281 active site 413999012282 metal binding site [ion binding]; metal-binding site 413999012283 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 413999012284 Pfam match to entry PF00986 DNA_gyraseB_C, DNA gyrase B subunit, carboxyl terminus, score 145.2, E-value 1.2e-40 413999012285 Pfam match to entry PF01751 Toprim, Toprim domain,score 20.5, E-value 0.0012 413999012286 PS00177 DNA topoisomerase II signature. 413999012287 Pfam match to entry PF00204 DNA_gyraseB, DNA gyrase B, score 202.4, E-value 7.3e-58 413999012288 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 93.9,E-value 3.4e-25 413999012289 1 probable transmembrane helix predicted for CBO2771 by TMHMM2.0 at aa 5-27 413999012290 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 413999012291 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 413999012292 Pfam match to entry PF00999 Na_H_Exchanger,Sodium/hydrogen exchanger family, score 105.4, E-value 9.9e-29 413999012293 12 probable transmembrane helices predicted for CBO2772 by TMHMM2.0 at aa 4-21, 28-47, 57-79, 86-108,112-134, 146-168, 188-210, 223-245, 260-282, 295-317,327-346 and 359-378 413999012294 1 probable transmembrane helix predicted for CBO2774 by TMHMM2.0 at aa 10-27 413999012295 Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944 413999012296 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 413999012297 NodB motif; other site 413999012298 active site 413999012299 catalytic site [active] 413999012300 Zn binding site [ion binding]; other site 413999012301 1 probable transmembrane helix predicted for CBO2775 by TMHMM2.0 at aa 21-43 413999012302 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 116.0, E-value 7.3e-32 413999012303 UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087 413999012304 UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247 413999012305 NAD binding site [chemical binding]; other site 413999012306 homodimer interface [polypeptide binding]; other site 413999012307 active site 413999012308 substrate binding site [chemical binding]; other site 413999012309 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase, score 530.2,E-value 1.5e-156 413999012310 flavodoxin; Provisional; Region: PRK05568 413999012311 Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426 413999012312 Pfam match to entry PF00258 flavodoxin, Flavodoxin,score 72.3, E-value 1.1e-18 413999012313 PS00201 Flavodoxin signature. 413999012314 1 probable transmembrane helix predicted for CBO2779 by TMHMM2.0 at aa 9-31 413999012315 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999012316 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 413999012317 12 probable transmembrane helices predicted for CBO2780 by TMHMM2.0 at aa 20-39, 54-76, 97-119, 141-163,170-190, 195-217, 243-265, 280-302, 322-344, 364-386,393-415 and 419-441 413999012318 Pfam match to entry PF01554 MatE, MatE, score 76.1,E-value 7.9e-20 413999012319 Pfam match to entry PF01554 MatE, MatE, score 97.1,E-value 3.6e-26 413999012320 Cupin domain; Region: Cupin_2; cl17218 413999012321 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 413999012322 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999012323 Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3664 413999012324 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 55.2, E-value 1.4e-13 413999012325 PS00041 Bacterial regulatory proteins, araC family signature. 413999012326 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 24.1, E-value 0.00034 413999012327 Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062 413999012328 putative dimer interface [polypeptide binding]; other site 413999012329 catalytic triad [active] 413999012330 Pfam match to entry PF02016 Peptidase_U61,LD-carboxypeptidase, score 87.7, E-value 2.4e-23 413999012331 glycerol kinase; Provisional; Region: glpK; PRK00047 413999012332 Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786 413999012333 N- and C-terminal domain interface [polypeptide binding]; other site 413999012334 active site 413999012335 MgATP binding site [chemical binding]; other site 413999012336 catalytic site [active] 413999012337 metal binding site [ion binding]; metal-binding site 413999012338 glycerol binding site [chemical binding]; other site 413999012339 homotetramer interface [polypeptide binding]; other site 413999012340 homodimer interface [polypeptide binding]; other site 413999012341 FBP binding site [chemical binding]; other site 413999012342 protein IIAGlc interface [polypeptide binding]; other site 413999012343 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain, score 327.3,E-value 1.9e-95 413999012344 PS00445 FGGY family of carbohydrate kinases signature 2. 413999012345 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain, score 386.4,E-value 2.9e-113 413999012346 PS00933 FGGY family of carbohydrate kinases signature 1. 413999012347 Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333 413999012348 amphipathic channel; other site 413999012349 Asn-Pro-Ala signature motifs; other site 413999012350 6 probable transmembrane helices predicted for CBO2785 by TMHMM2.0 at aa 5-27, 36-58, 86-108, 134-153,163-185 and 211-233 413999012351 Pfam match to entry PF00230 MIP, Major intrinsic protein, score 196.8, E-value 3.7e-56 413999012352 PS00221 MIP family signature. 413999012353 Putative heavy-metal-binding; Region: YbjQ_1; cl00426 413999012354 Pfam match to entry PF01906 DUF74, Domain of unknown function DUF74, score 201.1, E-value 1.8e-57 413999012355 VanZ like family; Region: VanZ; pfam04892 413999012356 6 probable transmembrane helices predicted for CBO2787 by TMHMM2.0 at aa 10-29, 36-58, 102-124, 137-154,164-181 and 202-224 413999012357 Pfam match to entry PF04892 VanZ, VanZ like family,score 72.5, E-value 9.3e-19 413999012358 7 probable transmembrane helices predicted for CBO2788 by TMHMM2.0 at aa 65-87, 116-138, 153-171,178-200, 264-281, 302-321 and 331-353 413999012359 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999012360 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999012361 Walker A/P-loop; other site 413999012362 ATP binding site [chemical binding]; other site 413999012363 Q-loop/lid; other site 413999012364 ABC transporter signature motif; other site 413999012365 Walker B; other site 413999012366 D-loop; other site 413999012367 H-loop/switch region; other site 413999012368 Pfam match to entry PF00005 ABC_tran, ABC transporter score 161.1, E-value 2e-45 413999012369 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999012370 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012371 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999012372 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999012373 DNA-binding site [nucleotide binding]; DNA binding site 413999012374 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 72.7, E-value 7.9e-19 413999012375 VanZ like family; Region: VanZ; cl01971 413999012376 5 probable transmembrane helices predicted for CBO2791 by TMHMM2.0 at aa 17-39, 76-93, 106-125, 130-147 and 160-182 413999012377 Pfam match to entry PF04892 VanZ, VanZ like family,score 70.3, E-value 4.4e-18 413999012378 hybrid cluster protein; Provisional; Region: PRK05290 413999012379 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999012380 ACS interaction site; other site 413999012381 CODH interaction site; other site 413999012382 Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914 413999012383 hybrid metal cluster; other site 413999012384 Pfam match to entry PF03063 Prismane, Prismane/CO dehydrogenase, score 988.1, E-value 2.2e-294 413999012385 6 probable transmembrane helices predicted for CBO2793 by TMHMM2.0 at aa 10-32, 37-56, 66-88, 95-113,128-150 and 171-193 413999012386 Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073 413999012387 Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309 413999012388 Pfam match to entry PF02073 Peptidase_M29,Thermophilic metalloprotease (M29), score 788.1, E-value 3.6e-234 413999012389 germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887 413999012390 Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504 413999012391 Pfam match to entry PF05504 Spore_GerAC, Spore germination B3/ GerAC like, C-terminal, score 74.4,E-value 2.5e-19 413999012392 1 probable transmembrane helix predicted for CBO2795 by TMHMM2.0 at aa 21-38 413999012393 Spore germination protein; Region: Spore_permease; pfam03845 413999012394 10 probable transmembrane helices predicted for CBO2796 by TMHMM2.0 at aa 13-32, 42-64, 85-107, 117-139,151-173, 193-210, 223-245, 260-282, 303-325 and 335-357 413999012395 Pfam match to entry PF03845 Spore_permease, Spore germination protein, score 396.0, E-value 3.9e-116 413999012396 Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323 413999012397 Pfam match to entry PF03323 GerA,Bacillus/Clostridium GerA spore germination protein, score 437.3, E-value 1.5e-128 413999012398 3 probable transmembrane helices predicted for CBO2797 by TMHMM2.0 at aa 284-306, 376-398 and 411-433 413999012399 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 413999012400 pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343 413999012401 PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP, present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727 413999012402 active site 413999012403 multimer interface [polypeptide binding]; other site 413999012404 Pfam match to entry PF01680 SOR_SNZ, SOR/SNZ family, score 427.6, E-value 1.2e-125 413999012405 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 413999012406 Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944 413999012407 NodB motif; other site 413999012408 active site 413999012409 catalytic site [active] 413999012410 Zn binding site [ion binding]; other site 413999012411 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 140.8, E-value 2.6e-39 413999012412 1 probable transmembrane helix predicted for CBO2801 by TMHMM2.0 at aa 10-27 413999012413 Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513 413999012414 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 413999012415 ATP binding site [chemical binding]; other site 413999012416 Mg++ binding site [ion binding]; other site 413999012417 motif III; other site 413999012418 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999012419 nucleotide binding region [chemical binding]; other site 413999012420 ATP-binding site [chemical binding]; other site 413999012421 RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252 413999012422 RNA binding site [nucleotide binding]; other site 413999012423 Pfam match to entry PF03880 DbpA, DbpA RNA binding domain, score 72.9, E-value 7.1e-19 413999012424 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 125.1, E-value 1.4e-34 413999012425 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 278.6, E-value 8.2e-81 413999012426 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 413999012427 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012428 Probable zinc-binding domain; Region: zf-trcl; pfam13451 413999012429 1 probable transmembrane helix predicted for CBO2804 by TMHMM2.0 at aa 7-24 413999012430 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999012431 dimer interface [polypeptide binding]; other site 413999012432 Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015 413999012433 putative CheW interface [polypeptide binding]; other site 413999012434 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 46.0, E-value 9e-11 413999012435 Pfam match to entry PF00672 HAMP, HAMP domain,score 37.9, E-value 2.4e-08 413999012436 2 probable transmembrane helices predicted for CBO2805 by TMHMM2.0 at aa 7-29 and 179-201 413999012437 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 413999012438 Ligand Binding Site [chemical binding]; other site 413999012439 Pfam match to entry PF00582 Usp, Universal stress protein family, score 28.6, E-value 9.7e-08 413999012440 Polyferredoxin [Energy production and conversion]; Region: NapH; COG0348 413999012441 4Fe-4S binding domain; Region: Fer4_5; pfam12801 413999012442 3 probable transmembrane helices predicted for CBO2807 by TMHMM2.0 at aa 15-47, 83-102 and 112-134 413999012443 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 12.8, E-value 0.0024 413999012444 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999012445 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 20.6, E-value 0.00014 413999012446 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999012447 glutaminase; Provisional; Region: PRK00971 413999012448 Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066 413999012449 Pfam match to entry PF04960 Glutaminase,Glutaminase, score 540.5, E-value 1.2e-159 413999012450 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883 413999012451 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584 413999012452 1 probable transmembrane helix predicted for CBO2809 by TMHMM2.0 at aa 5-27 413999012453 1 probable transmembrane helix predicted for CBO2810 by TMHMM2.0 at aa 4-26 413999012454 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999012455 Cache domain; Region: Cache_1; pfam02743 413999012456 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999012457 dimerization interface [polypeptide binding]; other site 413999012458 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999012459 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999012460 dimer interface [polypeptide binding]; other site 413999012461 putative CheW interface [polypeptide binding]; other site 413999012462 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 123.6, E-value 3.9e-34 413999012463 Pfam match to entry PF00672 HAMP, HAMP domain,score 45.2, E-value 1.5e-10 413999012464 2 probable transmembrane helices predicted for CBO2811 by TMHMM2.0 at aa 15-34 and 305-324 413999012465 Pfam match to entry PF02743 Cache, Cache domain,score 78.1, E-value 1.9e-20 413999012466 TraX protein; Region: TraX; cl05434 413999012467 9 probable transmembrane helices predicted for CBO2812 by TMHMM2.0 at aa 13-30, 40-59, 66-85, 95-117,130-152, 162-184, 191-213, 218-235 and 242-264 413999012468 ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966 413999012469 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 413999012470 dimer interface [polypeptide binding]; other site 413999012471 putative radical transfer pathway; other site 413999012472 diiron center [ion binding]; other site 413999012473 tyrosyl radical; other site 413999012474 Pfam match to entry PF00268 ribonuc_red_sm,Ribonucleotide reductase, small chain, score 81.9, E-value 1.3e-21 413999012475 ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07088 413999012476 ATP cone domain; Region: ATP-cone; pfam03477 413999012477 Class I ribonucleotide reductase; Region: RNR_I; cd01679 413999012478 active site 413999012479 dimer interface [polypeptide binding]; other site 413999012480 catalytic residues [active] 413999012481 effector binding site; other site 413999012482 R2 peptide binding site; other site 413999012483 Pfam match to entry PF02867 ribonuc_red_lgC,Ribonucleotide reductase, barrel domain, score 399.3,E-value 3.8e-117 413999012484 PS00089 Ribonucleotide reductase large subunit signature. 413999012485 Pfam match to entry PF00317 ribonuc_red_lg,Ribonucleotide reductase, all-alpha domain, score 100.7,E-value 3e-27 413999012486 Pfam match to entry PF03477 ATP-cone, ATP cone domain, score 48.5, E-value 1.6e-11 413999012487 Pfam match to entry PF02677 DUF208, Uncharacterized BCR, COG1636, score 96.1, E-value 2.8e-26 413999012488 Putative amidase domain; Region: Amidase_6; pfam12671 413999012489 1 probable transmembrane helix predicted for CBO2816 by TMHMM2.0 at aa 13-32 413999012490 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539 413999012491 DNA polymerase IV; Provisional; Region: PRK14133 413999012492 DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586 413999012493 active site 413999012494 DNA binding site [nucleotide binding] 413999012495 Pfam match to entry PF00817 IMS, impB/mucB/samB family, score 352.5, E-value 4.8e-103 413999012496 dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318 413999012497 Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940 413999012498 homodimer interface [polypeptide binding]; other site 413999012499 active site 413999012500 FMN binding site [chemical binding]; other site 413999012501 substrate binding site [chemical binding]; other site 413999012502 4Fe-4S binding domain; Region: Fer4; pfam00037 413999012503 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 28.7, E-value 7.7e-06 413999012504 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999012505 PS00190 Cytochrome c family heme-binding site signature. 413999012506 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 15.9, E-value 0.00079 413999012507 Pfam match to entry PF01180 DHOdehase,Dihydroorotate dehydrogenase, score -0.6, E-value 1.8e-10 413999012508 NADPH-dependent glutamate synthase beta chain and related oxidoreductases [Amino acid transport and metabolism / General function prediction only]; Region: GltD; COG0493 413999012509 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999012510 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 75.4, E-value 1.2e-19 413999012511 PS00190 Cytochrome c family heme-binding site signature. 413999012512 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065 413999012513 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999012514 active site 413999012515 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 80.2, E-value 4.6e-21 413999012516 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 413999012517 Uncharacterized conserved protein [Function unknown]; Region: COG1434 413999012518 putative active site [active] 413999012519 6 probable transmembrane helices predicted for CBO2822 by TMHMM2.0 at aa 4-19, 26-48, 58-80, 93-115,130-152 and 324-346 413999012520 Pfam match to entry PF02698 DUF218, Uncharacterized ACR, COG1434, score -35.1, E-value 2e-05 413999012521 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999012522 MarR family; Region: MarR_2; pfam12802 413999012523 Pfam match to entry PF01047 MarR, MarR family,score 64.0, E-value 3.4e-16 413999012524 Predicted helix-turn-helix motif with score 1560.000, SD 4.50 at aa 36-57, sequence KTTKELAEIRGITQPGISKLNK 413999012525 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999012526 Walker A/P-loop; other site 413999012527 ATP binding site [chemical binding]; other site 413999012528 Q-loop/lid; other site 413999012529 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 413999012530 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999012531 putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608 413999012532 Walker A/P-loop; other site 413999012533 ATP binding site [chemical binding]; other site 413999012534 Q-loop/lid; other site 413999012535 ABC transporter signature motif; other site 413999012536 Walker B; other site 413999012537 D-loop; other site 413999012538 H-loop/switch region; other site 413999012539 Pfam match to entry PF00005 ABC_tran, ABC transporter score 89.1, E-value 9.2e-24 413999012540 PS00211 ABC transporters family signature. 413999012541 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012542 Pfam match to entry PF00005 ABC_tran, ABC transporter score 31.1, E-value 1.9e-08 413999012543 PS00211 ABC transporters family signature. 413999012544 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012545 Protein of unknown function (DUF2628); Region: DUF2628; pfam10947 413999012546 2 probable transmembrane helices predicted for CBO2825 by TMHMM2.0 at aa 17-34 and 44-66 413999012547 2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258 413999012548 LigT like Phosphoesterase; Region: LigT_PEase; pfam02834 413999012549 LigT like Phosphoesterase; Region: LigT_PEase; pfam02834 413999012550 Pfam match to entry PF02834 2_5_ligase, 2',5' RNA ligase, score 28.7, E-value 1.1e-05 413999012551 Carbohydrate binding domain; Region: CBM_25; smart01066 413999012552 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 413999012553 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 413999012554 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999012555 dimerization interface [polypeptide binding]; other site 413999012556 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999012557 dimer interface [polypeptide binding]; other site 413999012558 putative CheW interface [polypeptide binding]; other site 413999012559 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 98.8, E-value 1.1e-26 413999012560 Pfam match to entry PF00672 HAMP, HAMP domain,score 56.9, E-value 4.7e-14 413999012561 2 probable transmembrane helices predicted for CBO2828 by TMHMM2.0 at aa 13-35 and 189-211 413999012562 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_17; cd04676 413999012563 nudix motif; other site 413999012564 Pfam match to entry PF00293 NUDIX, NUDIX domain,score 108.1, E-value 1.8e-29 413999012565 PS00893 mutT domain signature. 413999012566 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 413999012567 metal binding site 2 [ion binding]; metal-binding site 413999012568 putative DNA binding helix; other site 413999012569 metal binding site 1 [ion binding]; metal-binding site 413999012570 dimer interface [polypeptide binding]; other site 413999012571 structural Zn2+ binding site [ion binding]; other site 413999012572 Pfam match to entry PF01475 FUR, Ferric uptake regulator family, score 92.2, E-value 1.1e-24 413999012573 Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101 413999012574 Glyco_18 domain; Region: Glyco_18; smart00636 413999012575 The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548 413999012576 active site 413999012577 Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101 413999012578 Pfam match to entry PF00704 Glyco_hydro_18,Glycosyl hydrolases family 18, score 394.9, E-value 8.1e-116 413999012579 1 probable transmembrane helix predicted for CBO2832 by TMHMM2.0 at aa 9-28 413999012580 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363 413999012581 GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399 413999012582 active site 413999012583 trimer interface [polypeptide binding]; other site 413999012584 allosteric site; other site 413999012585 active site lid [active] 413999012586 hexamer (dimer of trimers) interface [polypeptide binding]; other site 413999012587 Pfam match to entry PF01182 Glucosamine_iso,Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase, score 299.9, E-value 3.2e-87 413999012588 PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 413999012589 N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820 413999012590 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854 413999012591 active site 413999012592 dimer interface [polypeptide binding]; other site 413999012593 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 37.5, E-value 3.3e-08 413999012594 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 413999012595 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999012596 DNA-binding site [nucleotide binding]; DNA binding site 413999012597 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 413999012598 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 83.0, E-value 6.6e-22 413999012599 transcriptional antiterminator BglG; Provisional; Region: PRK09772 413999012600 CAT RNA binding domain; Region: CAT_RBD; smart01061 413999012601 PRD domain; Region: PRD; pfam00874 413999012602 PRD domain; Region: PRD; pfam00874 413999012603 Pfam match to entry PF03123 CAT_RBD, CAT RNA binding domain, score 64.0, E-value 3.3e-16 413999012604 Pfam match to entry PF00874 PRD, PRD domain, score 113.5, E-value 4.3e-31 413999012605 Pfam match to entry PF00874 PRD, PRD domain, score 105.9, E-value 8.4e-29 413999012606 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 413999012607 HPr interaction site; other site 413999012608 glycerol kinase (GK) interaction site [polypeptide binding]; other site 413999012609 active site 413999012610 phosphorylation site [posttranslational modification] 413999012611 Pfam match to entry PF00358 PTS_EIIA_1,phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1, score 177.2, E-value 2.9e-50 413999012612 PS00371 PTS EIIA domains phosphorylation site signature 1. 413999012613 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 413999012614 PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998 413999012615 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 413999012616 active site turn [active] 413999012617 phosphorylation site [posttranslational modification] 413999012618 9 probable transmembrane helices predicted for CBO2839 by TMHMM2.0 at aa 13-35, 55-77, 105-124, 144-163,170-192, 237-259, 271-288, 303-325 and 346-368 413999012619 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 319.3, E-value 4.9e-93 413999012620 Pfam match to entry PF00367 PTS_EIIB,phosphotransferase system, EIIB, score 49.7, E-value 6.6e-12 413999012621 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 413999012622 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 413999012623 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999012624 12 probable transmembrane helices predicted for CBO2840 by TMHMM2.0 at aa 20-42, 52-74, 94-116, 136-158,167-186, 196-215, 236-258, 273-295, 315-334, 360-382,389-411 and 416-438 413999012625 Pfam match to entry PF01554 MatE, MatE, score 108.4, E-value 1.5e-29 413999012626 Pfam match to entry PF01554 MatE, MatE, score 64.8,E-value 1.9e-16 413999012627 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 413999012628 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 413999012629 12 probable transmembrane helices predicted for CBO2841 by TMHMM2.0 at aa 21-40, 60-82, 103-125, 140-162,169-188, 198-220, 241-263, 273-295, 327-349, 359-381,388-410 and 420-442 413999012630 Pfam match to entry PF01554 MatE, MatE, score 95.0,E-value 1.6e-25 413999012631 Pfam match to entry PF01554 MatE, MatE, score 123.4, E-value 4.5e-34 413999012632 Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426 413999012633 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999012634 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 413999012635 Pfam match to entry PF00258 flavodoxin, Flavodoxin,score 28.5, E-value 4.1e-07 413999012636 PS00201 Flavodoxin signature. 413999012637 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 70.8, E-value 2.9e-18 413999012638 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 413999012639 Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158 413999012640 FAD binding site [chemical binding]; other site 413999012641 homotetramer interface [polypeptide binding]; other site 413999012642 substrate binding pocket [chemical binding]; other site 413999012643 catalytic base [active] 413999012644 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 413999012645 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 413999012646 Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730 413999012647 Rubredoxin; Region: Rubredoxin; pfam00301 413999012648 iron binding site [ion binding]; other site 413999012649 Pfam match to entry PF00301 rubredoxin, Rubredoxin,score 78.4, E-value 1.5e-20 413999012650 PS00202 Rubredoxin signature. 413999012651 PS00696 Electron transfer flavoprotein alpha-subunit signature. 413999012652 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit, score -31.0, E-value 8.4e-09 413999012653 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain, score 268.5, E-value 9.3e-78 413999012654 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain, score 182.1, E-value 9.4e-52 413999012655 PS00072 Acyl-CoA dehydrogenases signature 1. 413999012656 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain, score 154.4, E-value 2.1e-43 413999012657 Pfam match to entry PF00665 rve, Integrase core domain, score 114.4, E-value 2.2e-31 413999012658 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716 413999012659 Pfam match to entry PF03613 EIID-AGA, PTS system mannose/fructose/sorbose family IID component, score 626.3, E-value 1.8e-185 413999012660 4 probable transmembrane helices predicted for CBO2845 by TMHMM2.0 at aa 151-173, 210-229, 286-303 and 310-328 413999012661 Domain of unknown function (DUF956); Region: DUF956; pfam06115 413999012662 Pfam match to entry PF06115 DUF956, Domain of unknown function (DUF956), score 253.2, E-value 3.8e-73 413999012663 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788 413999012664 Pfam match to entry PF01144 CoA_trans, Coenzyme A transferase, score 255.3, E-value 8.4e-74 413999012665 Coenzyme A transferase; Region: CoA_trans; cl17247 413999012666 Pfam match to entry PF01144 CoA_trans, Coenzyme A transferase, score 171.8, E-value 1.2e-48 413999012667 GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182 413999012668 Ligand binding site; other site 413999012669 metal-binding site 413999012670 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012671 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 413999012672 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 413999012673 catalytic loop [active] 413999012674 iron binding site [ion binding]; other site 413999012675 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 413999012676 Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding domain, score 90.1, E-value 4.7e-24 413999012677 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain, score 14.2, E-value 0.011 413999012678 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 413999012679 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319 413999012680 CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092 413999012681 Pfam match to entry PF00941 FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase, score -18.9, E-value 2.5e-05 413999012682 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 413999012683 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 413999012684 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 413999012685 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain, score 322.0, E-value 7e-94 413999012686 Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain,score 124.2, E-value 2.6e-34 413999012687 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 413999012688 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 413999012689 Pfam match to entry PF00999 Na_H_Exchanger,Sodium/hydrogen exchanger family, score 225.5, E-value 8.2e-65 413999012690 9 probable transmembrane helices predicted for CBO2853 by TMHMM2.0 at aa 32-51, 86-108, 123-142, 155-177,187-209, 222-244, 274-291, 304-326 and 365-387 413999012691 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 413999012692 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999012693 motif II; other site 413999012694 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 71.2, E-value 2.3e-18 413999012695 chloramphenicol/florfenicol resistance protein; Provisional; Region: PRK14453 413999012696 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999012697 FeS/SAM binding site; other site 413999012698 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 54.7, E-value 2.2e-13 413999012699 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 413999012700 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999012701 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999012702 Pfam match to entry PF00005 ABC_tran, ABC transporter score 106.2, E-value 6.6e-29 413999012703 PS00211 ABC transporters family signature. 413999012704 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012705 Pfam match to entry PF00005 ABC_tran, ABC transporter score 99.8, E-value 5.6e-27 413999012706 PS00211 ABC transporters family signature. 413999012707 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012708 TRAM domain; Region: TRAM; cl01282 413999012709 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265 413999012710 4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711 413999012711 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999012712 S-adenosylmethionine binding site [chemical binding]; other site 413999012713 Pfam match to entry PF05958 tRNA_U5-meth_tr, tRNA (Uracil-5-)-methyltransferase, score -66.5, E-value 1.8e-09 413999012714 PS01231 RNA methyltransferase trmA family signature 2. 413999012715 PS01230 RNA methyltransferase trmA family signature 1. 413999012716 Pfam match to entry PF01938 TRAM, TRAM domain,score 34.1, E-value 3.4e-07 413999012717 2 probable transmembrane helices predicted for CBO2860 by TMHMM2.0 at aa 93-115 and 120-139 413999012718 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368 413999012719 Sulfatase; Region: Sulfatase; pfam00884 413999012720 5 probable transmembrane helices predicted for CBO2861 by TMHMM2.0 at aa 7-29, 42-60, 67-89, 115-137 and 150-171 413999012721 Pfam match to entry PF00884 Sulfatase, Sulfatase,score 94.4, E-value 2.4e-25 413999012722 hypothetical protein; Provisional; Region: PRK10621 413999012723 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 413999012724 Pfam match to entry PF01925 DUF81, Domain of unknown function DUF81, score 145.4, E-value 1.1e-40 413999012725 4 probable transmembrane helices predicted for CBO2862 by TMHMM2.0 at aa 15-37, 71-93, 98-115 and 136-158 413999012726 lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209 413999012727 homopentamer interface [polypeptide binding]; other site 413999012728 active site 413999012729 Pfam match to entry PF00885 DMRL_synthase,6,7-dimethyl-8-ribityllumazine synthase, score 299.8,E-value 3.5e-87 413999012730 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311 413999012731 3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926 413999012732 GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641 413999012733 dimerization interface [polypeptide binding]; other site 413999012734 active site 413999012735 Pfam match to entry PF00925 GTP_cyclohydro2, GTP cyclohydrolase II, score 385.2, E-value 6.8e-113 413999012736 Pfam match to entry PF00926 DHBP_synthase,3,4-dihydroxy-2-butanone 4-phosphate synthase, score 424.7, E-value 8.7e-125 413999012737 riboflavin synthase subunit alpha; Provisional; Region: PRK09289 413999012738 Lumazine binding domain; Region: Lum_binding; pfam00677 413999012739 Lumazine binding domain; Region: Lum_binding; pfam00677 413999012740 Pfam match to entry PF00677 Lum_binding, Lumazine binding domain, score 94.0, E-value 3.1e-25 413999012741 Pfam match to entry PF00677 Lum_binding, Lumazine binding domain, score 102.7, E-value 7.7e-28 413999012742 riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326 413999012743 Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284 413999012744 catalytic motif [active] 413999012745 Zn binding site [ion binding]; other site 413999012746 RibD C-terminal domain; Region: RibD_C; cl17279 413999012747 Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893 413999012748 M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890 413999012749 metal binding site [ion binding]; metal-binding site 413999012750 dimer interface [polypeptide binding]; other site 413999012751 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 128.4, E-value 1.4e-35 413999012752 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999012753 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 76.5, E-value 5.8e-20 413999012754 magnesium-transporting ATPase; Provisional; Region: PRK15122 413999012755 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 413999012756 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999012757 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 413999012758 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999012759 motif II; other site 413999012760 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 413999012761 8 probable transmembrane helices predicted for CBO2869 by TMHMM2.0 at aa 78-100, 104-121, 270-292,302-324, 692-714, 751-773, 815-837 and 847-869 413999012762 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 72.2, E-value 1.2e-18 413999012763 PS00154 E1-E2 ATPases phosphorylation site. 413999012764 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 259.1, E-value 6.1e-75 413999012765 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus, score 81.8, E-value 1.4e-21 413999012766 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 413999012767 active site 413999012768 phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885 413999012769 Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844 413999012770 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071 413999012771 Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843 413999012772 Pfam match to entry PF02843 GARS_C,Phosphoribosylglycinamide synthetase, C domain, score 94.0, E-value 3.1e-25 413999012773 Pfam match to entry PF01071 GARS,Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain, score 216.8, E-value 3.3e-62 413999012774 Pfam match to entry PF02842 GARS_B,Phosphoribosylglycinamide synthetase, B domain, score 124.2, E-value 2.5e-34 413999012775 Pfam match to entry PF02844 GARS_N,Phosphoribosylglycinamide synthetase, N domain, score 168.8, E-value 9.8e-48 413999012776 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881 413999012777 Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates...; Region: IMPCH; cd01421 413999012778 purine monophosphate binding site [chemical binding]; other site 413999012779 dimer interface [polypeptide binding]; other site 413999012780 putative catalytic residues [active] 413999012781 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798 413999012782 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362 413999012783 Pfam match to entry PF01808 AICARFT_IMPCHas,AICARFT/IMPCHase bienzyme, score 476.3, E-value 2.6e-140 413999012784 Pfam match to entry PF02142 MGS, MGS-like domain,score 151.6, E-value 1.4e-42 413999012785 phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647 413999012786 Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645 413999012787 active site 413999012788 substrate binding site [chemical binding]; other site 413999012789 cosubstrate binding site; other site 413999012790 catalytic site [active] 413999012791 Pfam match to entry PF00551 formyl_transf, Formyl transferase, score 204.7, E-value 1.5e-58 413999012792 phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385 413999012793 PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196 413999012794 dimerization interface [polypeptide binding]; other site 413999012795 putative ATP binding site [chemical binding]; other site 413999012796 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain, score 133.2, E-value 5e-37 413999012797 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain, score 221.0, E-value 1.9e-63 413999012798 amidophosphoribosyltransferase; Provisional; Region: PRK05793 413999012799 Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715 413999012800 active site 413999012801 tetramer interface [polypeptide binding]; other site 413999012802 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999012803 active site 413999012804 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 58.6, E-value 1.4e-14 413999012805 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 413999012806 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II, score 147.7, E-value 2.2e-41 413999012807 phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362 413999012808 bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415 413999012809 ATP binding site [chemical binding]; other site 413999012810 active site 413999012811 substrate binding site [chemical binding]; other site 413999012812 Pfam match to entry PF01259 SAICAR_synt, SAICAR synthetase, score 293.4, E-value 2.9e-85 413999012813 PS01057 SAICAR synthetase signature 1. 413999012814 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041 413999012815 Pfam match to entry PF00731 AIRC, AIR carboxylase,score 239.9, E-value 3.8e-69 413999012816 selenium-dependent molybdenum hydroxylase 1; Region: Se_dep_Molyb_1; TIGR03311 413999012817 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 413999012818 catalytic loop [active] 413999012819 iron binding site [ion binding]; other site 413999012820 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 413999012821 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 413999012822 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 413999012823 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain, score 389.1, E-value 4.6e-114 413999012824 Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain,score 99.2, E-value 8.4e-27 413999012825 Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding domain, score 95.2, E-value 1.3e-25 413999012826 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain, score 21.5, E-value 0.0021 413999012827 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 413999012828 putative selenium metabolism hydrolase; Region: selenium_YgeY; TIGR03526 413999012829 M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649 413999012830 putative metal binding site [ion binding]; other site 413999012831 putative dimer interface [polypeptide binding]; other site 413999012832 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 246.2, E-value 4.6e-71 413999012833 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 413999012834 PS00148 Arginase signature 2. 413999012835 putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203 413999012836 TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298 413999012837 active site 413999012838 putative substrate binding pocket [chemical binding]; other site 413999012839 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 140.2, E-value 3.9e-39 413999012840 putative selenate reductase, YgfK subunit; Region: Se_ygfK; TIGR03315 413999012841 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999012842 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999012843 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 98.1, E-value 1.8e-26 413999012844 aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200 413999012845 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 413999012846 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 413999012847 Pfam match to entry PF00185 OTCace,Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain, score -21.6, E-value 2.8e-05 413999012848 Pfam match to entry PF02729 OTCace_N,Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain, score 26.0, E-value 3.1e-08 413999012849 phenylhydantoinase; Validated; Region: PRK08323 413999012850 D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314 413999012851 tetramer interface [polypeptide binding]; other site 413999012852 active site 413999012853 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 12.4, E-value 3.7e-05 413999012854 xanthine permease; Region: pbuX; TIGR03173 413999012855 12 probable transmembrane helices predicted for CBO2887 by TMHMM2.0 at aa 21-43, 53-75, 80-102, 112-131,144-166, 181-198, 205-224, 239-261, 328-350, 355-377,389-408 and 418-437 413999012856 Pfam match to entry PF00860 xan_ur_permease,Permease, score 415.0, E-value 7.2e-122 413999012857 PS01116 Xanthine/uracil permeases family signature. 413999012858 Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171 413999012859 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640 413999012860 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999012861 catalytic residue [active] 413999012862 Pfam match to entry PF00291 PALP,Pyridoxal-phosphate dependent enzyme, score 44.7, E-value 2.2e-10 413999012863 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829 413999012864 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999012865 Walker A motif; other site 413999012866 ATP binding site [chemical binding]; other site 413999012867 Walker B motif; other site 413999012868 arginine finger; other site 413999012869 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999012870 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 34.1, E-value 3.5e-07 413999012871 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 419.3, E-value 3.6e-123 413999012872 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999012873 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999012874 probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172 413999012875 GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182 413999012876 Ligand binding site; other site 413999012877 metal-binding site 413999012878 selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309 413999012879 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975 413999012880 XdhC and CoxI family; Region: XdhC_CoxI; pfam02625 413999012881 XdhC Rossmann domain; Region: XdhC_C; pfam13478 413999012882 Pfam match to entry PF02625 XdhC_CoxI, XdhC and CoxI family, score 54.8, E-value 2e-13 413999012883 NTPase; Region: NTPase_1; pfam03266 413999012884 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 413999012885 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012886 Pfam match to entry PF03266 DUF265, Protein of unknown function, DUF265, score 48.9, E-value 5.3e-13 413999012887 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 413999012888 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 413999012889 ABC-ATPase subunit interface; other site 413999012890 dimer interface [polypeptide binding]; other site 413999012891 putative PBP binding regions; other site 413999012892 9 probable transmembrane helices predicted for CBO2895 by TMHMM2.0 at aa 7-24, 47-69, 82-101, 105-122,135-157, 186-208, 229-251, 261-283 and 296-315 413999012893 Pfam match to entry PF01032 FecCD, FecCD transport family, score 307.7, E-value 1.5e-89 413999012894 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 413999012895 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 413999012896 Walker A/P-loop; other site 413999012897 ATP binding site [chemical binding]; other site 413999012898 Q-loop/lid; other site 413999012899 ABC transporter signature motif; other site 413999012900 Walker B; other site 413999012901 D-loop; other site 413999012902 H-loop/switch region; other site 413999012903 Pfam match to entry PF00005 ABC_tran, ABC transporter score 151.0, E-value 2.1e-42 413999012904 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012905 PS00211 ABC transporters family signature. 413999012906 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 413999012907 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 413999012908 intersubunit interface [polypeptide binding]; other site 413999012909 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999012910 Pfam match to entry PF01497 Peripla_BP_2,Periplasmic binding protein, score 48.0, E-value 2.2e-11 413999012911 ALIX V-shaped domain binding to HIV; Region: ALIX_LYPXL_bnd; pfam13949 413999012912 1 probable transmembrane helix predicted for CBO2898 by TMHMM2.0 at aa 4-21 413999012913 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053 413999012914 active site 413999012915 catalytic triad [active] 413999012916 oxyanion hole [active] 413999012917 Pfam match to entry PF00657 Lipase_GDSL, GDSL-like Lipase/Acylhydrolase, score 87.2, E-value 3.4e-23 413999012918 Uncharacterized conserved protein [Function unknown]; Region: COG1434 413999012919 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 413999012920 putative active site [active] 413999012921 Pfam match to entry PF02698 DUF218, Uncharacterized ACR, COG1434, score 38.2, E-value 1.4e-11 413999012922 1 probable transmembrane helix predicted for CBO2900 by TMHMM2.0 at aa 12-34 413999012923 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 413999012924 13 probable transmembrane helices predicted for CBO2901 by TMHMM2.0 at aa 35-57, 86-108, 115-134, 138-157,170-192, 207-224, 231-253, 273-295, 331-353, 366-388,393-410, 425-447 and 460-478 413999012925 Pfam match to entry PF00860 xan_ur_permease,Permease, score 80.8, E-value 2.9e-21 413999012926 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 413999012927 amino acid carrier protein; Region: agcS; TIGR00835 413999012928 Pfam match to entry PF01235 Na_Ala_symp,Sodium:alanine symporter family, score 544.4, E-value 8.1e-161 413999012929 11 probable transmembrane helices predicted for CBO2902 by TMHMM2.0 at aa 15-37, 70-92, 97-119, 147-169,184-206, 213-230, 240-262, 301-323, 351-373, 386-405 and 415-434 413999012930 PS00873 Sodium:alanine symporter family signature. 413999012931 Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973 413999012932 Part of AAA domain; Region: AAA_19; pfam13245 413999012933 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 22.9, E-value 1.9e-06 413999012934 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 15.7, E-value 0.00018 413999012935 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012936 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482 413999012937 tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998 413999012938 Ligand Binding Site [chemical binding]; other site 413999012939 Pfam match to entry PF03054 tRNA_Me_trans, tRNA methyl transferase, score 532.0, E-value 4.4e-157 413999012940 M20 Peptidase Arginine utilization protein, RocB; Region: M20_ArgE_RocB; cd05654 413999012941 putative metal binding site [ion binding]; other site 413999012942 putative dimer interface [polypeptide binding]; other site 413999012943 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 32.5, E-value 2.8e-08 413999012944 GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956 413999012945 GAF domain; Region: GAF_2; pfam13185 413999012946 Pfam match to entry PF01590 GAF, GAF domain, score 24.3, E-value 3.9e-06 413999012947 PS01320 Uncharacterized protein family UPF0067 signature. 413999012948 Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253 413999012949 Domain of unknown function DUF21; Region: DUF21; pfam01595 413999012950 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 413999012951 Transporter associated domain; Region: CorC_HlyC; pfam03471 413999012952 Pfam match to entry PF01595 DUF21, Domain of unknown function DUF21, score 237.2, E-value 2.5e-68 413999012953 4 probable transmembrane helices predicted for CBO2909 by TMHMM2.0 at aa 7-29, 69-91, 111-128 and 143-165 413999012954 Pfam match to entry PF00571 CBS, CBS domain, score 51.2, E-value 2.3e-12 413999012955 Pfam match to entry PF00571 CBS, CBS domain, score 24.2, E-value 0.00033 413999012956 Pfam match to entry PF03471 CorC_HlyC, Transporter associated domain, score 95.3, E-value 1.2e-25 413999012957 Domain of unknown function DUF77; Region: DUF77; pfam01910 413999012958 Pfam match to entry PF01910 DUF77, Protein of unknown function DUF77, score 99.6, E-value 6.4e-27 413999012959 thiamine biosynthesis protein ThiC; Provisional; Region: PRK13352 413999012960 thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190 413999012961 Pfam match to entry PF01964 ThiC, ThiC family,score 782.4, E-value 1.9e-232 413999012962 amidophosphoribosyltransferase; Provisional; Region: PRK05793 413999012963 Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319 413999012964 active site 413999012965 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999012966 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 35.3, E-value 1.4e-07 413999012967 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 413999012968 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II, score 129.2, E-value 7.9e-36 413999012969 Protein of unknown function (DUF503); Region: DUF503; pfam04456 413999012970 Pfam match to entry PF04456 DUF503, Protein of unknown function (DUF503), score 127.7, E-value 2.2e-35 413999012971 ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346 413999012972 6 probable transmembrane helices predicted for CBO2915 by TMHMM2.0 at aa 20-42, 52-69, 99-121, 136-158,170-192 and 207-229 413999012973 ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346 413999012974 6 probable transmembrane helices predicted for CBO2916 by TMHMM2.0 at aa 9-31, 36-58, 85-107, 117-139,146-165 and 187-209 413999012975 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999012976 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999012977 Walker A/P-loop; other site 413999012978 ATP binding site [chemical binding]; other site 413999012979 Q-loop/lid; other site 413999012980 ABC transporter signature motif; other site 413999012981 Walker B; other site 413999012982 D-loop; other site 413999012983 H-loop/switch region; other site 413999012984 Pfam match to entry PF00005 ABC_tran, ABC transporter score 127.1, E-value 3.4e-35 413999012985 PS00211 ABC transporters family signature. 413999012986 PS00017 ATP/GTP-binding site motif A (P-loop). 413999012987 Predicted transcriptional regulators [Transcription]; Region: COG1725 413999012988 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999012989 DNA-binding site [nucleotide binding]; DNA binding site 413999012990 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 66.6, E-value 5.4e-17 413999012991 4 probable transmembrane helices predicted for CBO2919 by TMHMM2.0 at aa 2-24, 34-56, 100-122 and 132-154 413999012992 3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353 413999012993 3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108 413999012994 Pfam match to entry PF00926 DHBP_synthase,3,4-dihydroxy-2-butanone 4-phosphate synthase, score 377.0, E-value 2e-110 413999012995 Ferredoxin [Energy production and conversion]; Region: COG1146 413999012996 4Fe-4S binding domain; Region: Fer4_6; pfam12837 413999012997 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 21.4, E-value 0.00011 413999012998 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 33.5, E-value 5.1e-07 413999012999 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 413999013000 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 413999013001 ligand binding site [chemical binding]; other site 413999013002 flexible hinge region; other site 413999013003 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 413999013004 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain, score 32.7, E-value 8.6e-07 413999013005 Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486 413999013006 Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917 413999013007 Predicted membrane protein [Function unknown]; Region: COG1511 413999013008 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 413999013009 YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062 413999013010 6 probable transmembrane helices predicted for CBO2927 by TMHMM2.0 at aa 16-38, 519-541, 562-584,594-616, 623-645 and 675-697 413999013011 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 413999013012 Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563 413999013013 active site 413999013014 catalytic site [active] 413999013015 metal binding site [ion binding]; metal-binding site 413999013016 dimer interface [polypeptide binding]; other site 413999013017 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase, score 226.9, E-value 3.2e-65 413999013018 Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076 413999013019 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999013020 catalytic residue [active] 413999013021 Pfam match to entry PF00282 pyridoxal_deC,Pyridoxal-dependent decarboxylase domain, score -7.0, E-value 2.2e-14 413999013022 1 probable transmembrane helix predicted for CBO2932 by TMHMM2.0 at aa 28-50 413999013023 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score 28.5, E-value 8.4e-08 413999013024 Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579 413999013025 Putative zinc ribbon domain; Region: DUF164; pfam02591 413999013026 Pfam match to entry PF02591 DUF164, Uncharacterized ACR, COG1579, score 5.9, E-value 1.1e-06 413999013027 Uncharacterized conserved protein [Function unknown]; Region: COG0327 413999013028 NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784 413999013029 Pfam match to entry PF01784 NIF3, NIF3 (NGG1p interacting factor 3), score 339.1, E-value 5e-99 413999013030 Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384 413999013031 Family of unknown function (DUF633); Region: DUF633; pfam04816 413999013032 Pfam match to entry PF04816 DUF633, Family of unknown function (DUF633), score 227.3, E-value 2.3e-65 413999013033 Protein of unknown function (DUF2679); Region: DUF2679; pfam10882 413999013034 5 probable transmembrane helices predicted for CBO2937 by TMHMM2.0 at aa 7-29, 44-63, 186-208, 241-260 and 272-294 413999013035 RNA polymerase sigma factor RpoD; Validated; Region: PRK09210 413999013036 Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979 413999013037 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 413999013038 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999013039 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 413999013040 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999013041 DNA binding residues [nucleotide binding] 413999013042 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 94.0, E-value 3.1e-25 413999013043 PS00716 Sigma-70 factors family signature 2. 413999013044 Pfam match to entry PF04539 sigma70_r3, Sigma-70 region 3, score 153.4, E-value 4.2e-43 413999013045 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 107.6, E-value 2.5e-29 413999013046 PS00715 Sigma-70 factors family signature 1. 413999013047 Pfam match to entry PF00140 sigma70_r1_2, Sigma-70 factor, region 1.2, score 76.8, E-value 4.7e-20 413999013048 Pfam match to entry PF03979 sigma70_r1_1, Sigma-70 factor, region 1.1, score 75.7, E-value 9.8e-20 413999013049 DNA primase, catalytic core; Region: dnaG; TIGR01391 413999013050 CHC2 zinc finger; Region: zf-CHC2; pfam01807 413999013051 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 413999013052 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 413999013053 active site 413999013054 metal binding site [ion binding]; metal-binding site 413999013055 interdomain interaction site; other site 413999013056 DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410 413999013057 Pfam match to entry PF01751 Toprim, Toprim domain,score 87.6, E-value 2.6e-23 413999013058 Pfam match to entry PF01807 zf-CHC2, CHC2 zinc finger, score 184.5, E-value 1.8e-52 413999013059 deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286 413999013060 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999013061 Zn2+ binding site [ion binding]; other site 413999013062 Mg2+ binding site [ion binding]; other site 413999013063 Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286 413999013064 Pfam match to entry PF01966 HD, HD domain, score 68.4, E-value 1.6e-17 413999013065 spore coat protein YsxE; Region: spore_ysxE; TIGR02904 413999013066 spore coat protein, CotS family; Region: spore_CotS; TIGR02906 413999013067 pyruvate phosphate dikinase; Provisional; Region: PRK09279 413999013068 Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326 413999013069 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 413999013070 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 413999013071 Pfam match to entry PF02896 PEP-utilizers_C,PEP-utilising enzyme, TIM barrel domain, score 555.7,E-value 3.2e-164 413999013072 PS00742 PEP-utilizing enzymes signature 2. 413999013073 Pfam match to entry PF00391 PEP-utilizers,PEP-utilising enzyme, mobile domain, score 167.0, E-value 3.4e-47 413999013074 PS00370 PEP-utilizing enzymes phosphorylation site signature. 413999013075 Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain, score 628.3, E-value 4.5e-186 413999013076 HTH domain; Region: HTH_11; pfam08279 413999013077 FOG: CBS domain [General function prediction only]; Region: COG0517 413999013078 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617 413999013079 Pfam match to entry PF00571 CBS, CBS domain, score 29.0, E-value 1.2e-05 413999013080 Pfam match to entry PF00571 CBS, CBS domain, score 29.8, E-value 6.5e-06 413999013081 SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389 413999013082 Domain of unknown function (DUF4342); Region: DUF4342; pfam14242 413999013083 1 probable transmembrane helix predicted for CBO2944 by TMHMM2.0 at aa 92-114 413999013084 Pfam match to entry PF00627 UBA, UBA/TS-N domain,score 29.7, E-value 7e-06 413999013085 DNA repair protein RecO; Reviewed; Region: recO; PRK00085 413999013086 Recombination protein O N terminal; Region: RecO_N; pfam11967 413999013087 Recombination protein O C terminal; Region: RecO_C; pfam02565 413999013088 Pfam match to entry PF02565 RecO, Recombination protein O, score 20.1, E-value 7.5e-06 413999013089 GTPase Era; Reviewed; Region: era; PRK00089 413999013090 E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163 413999013091 G1 box; other site 413999013092 GTP/Mg2+ binding site [chemical binding]; other site 413999013093 Switch I region; other site 413999013094 G2 box; other site 413999013095 Switch II region; other site 413999013096 G3 box; other site 413999013097 G4 box; other site 413999013098 G5 box; other site 413999013099 Pfam match to entry PF00013 KH, KH domain, score 11.5, E-value 0.028 413999013100 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013101 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 413999013102 active site 413999013103 catalytic motif [active] 413999013104 Zn binding site [ion binding]; other site 413999013105 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region, score 110.2, E-value 4.2e-30 413999013106 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 413999013107 Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219 413999013108 PAP2_like proteins, diacylglycerol_kinase like sub-family. In some prokaryotes, PAP2_like phosphatase domains appear fused to E. coli DAGK-like trans-membrane diacylglycerol kinase domains. The cellular function of these architectures remains to be...; Region: PAP2_diacylglycerolkinase; cd03383 413999013109 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 413999013110 active site 413999013111 Pfam match to entry PF01569 PAP2, PAP2 superfamily,score 32.8, E-value 8.6e-07 413999013112 6 probable transmembrane helices predicted for CBO2948 by TMHMM2.0 at aa 27-44, 49-71, 91-113, 132-154,174-196 and 209-231 413999013113 Pfam match to entry PF01219 DAGK_prokar,Prokaryotic diacylglycerol kinase, score 119.8, E-value 5.3e-33 413999013114 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013115 metal-binding heat shock protein; Provisional; Region: PRK00016 413999013116 Pfam match to entry PF02130 UPF0054,Uncharacterized protein family UPF0054, score 132.6,E-value 7.6e-37 413999013117 PS01306 Uncharacterized protein family UPF0054 signature. 413999013118 Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480 413999013119 7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698 413999013120 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999013121 Zn2+ binding site [ion binding]; other site 413999013122 Mg2+ binding site [ion binding]; other site 413999013123 Pfam match to entry PF01966 HD, HD domain, score 84.8, E-value 1.9e-22 413999013124 6 probable transmembrane helices predicted for CBO2950 by TMHMM2.0 at aa 19-38, 268-290, 319-341,356-378, 391-413 and 423-445 413999013125 Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898 413999013126 sporulation protein YqfD; Region: spore_yqfD; TIGR02876 413999013127 1 probable transmembrane helix predicted for CBO2951 by TMHMM2.0 at aa 86-108 413999013128 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 413999013129 sporulation protein YqfC; Region: spore_yqfC; TIGR02856 413999013130 Yqey-like protein; Region: YqeY; pfam09424 413999013131 Pfam match to entry PF02637 GatB_Yqey, GatB/Yqey domain, score 76.1, E-value 7.5e-20 413999013132 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013133 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 413999013134 Pfam match to entry PF01165 Ribosomal_S21,Ribosomal protein S21, score 109.6, E-value 6.2e-30 413999013135 PS01181 Ribosomal protein S21 signature. 413999013136 Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276 413999013137 nucleotide binding site/active site [active] 413999013138 HIT family signature motif; other site 413999013139 catalytic residue [active] 413999013140 Pfam match to entry PF01230 HIT, HIT domain, score 164.9, E-value 1.4e-46 413999013141 PS00892 HIT family signature. 413999013142 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621 413999013143 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 413999013144 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999013145 FeS/SAM binding site; other site 413999013146 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 111.6, E-value 1.5e-30 413999013147 PS01278 Uncharacterized protein family UPF0004 signature. 413999013148 Pfam match to entry PF00919 UPF0004,Uncharacterized protein family UPF0004, score 143.7,E-value 3.5e-40 413999013149 16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713 413999013150 RNA methyltransferase, RsmE family; Region: TIGR00046 413999013151 Pfam match to entry PF04452 DUF558, Protein of unknown function (DUF558), score 154.2, E-value 2.4e-43 413999013152 Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325 413999013153 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 413999013154 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999013155 S-adenosylmethionine binding site [chemical binding]; other site 413999013156 Pfam match to entry PF06325 PrmA, Ribosomal protein L11 methyltransferase (PrmA), score 462.3, E-value 4.2e-136 413999013157 chaperone protein DnaJ; Provisional; Region: PRK14297 413999013158 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 413999013159 HSP70 interaction site [polypeptide binding]; other site 413999013160 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262 413999013161 substrate binding site [polypeptide binding]; other site 413999013162 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719 413999013163 Zn binding sites [ion binding]; other site 413999013164 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747 413999013165 dimer interface [polypeptide binding]; other site 413999013166 Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region, score 235.3, E-value 9.2e-68 413999013167 Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ central domain (4 repeats), score 149.3, E-value 7.2e-42 413999013168 PS00190 Cytochrome c family heme-binding site signature. 413999013169 PS00637 CXXCXGXG dnaJ domain signature. 413999013170 Pfam match to entry PF00226 DnaJ, DnaJ domain,score 153.9, E-value 2.9e-43 413999013171 PS00636 Nt-dnaJ domain signature. 413999013172 molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290 413999013173 Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234 413999013174 nucleotide binding site [chemical binding]; other site 413999013175 NEF interaction site [polypeptide binding]; other site 413999013176 SBD interface [polypeptide binding]; other site 413999013177 Pfam match to entry PF00012 HSP70, Hsp70 protein,score 1296.6, E-value 0 413999013178 PS01036 Heat shock hsp70 proteins family signature 3. 413999013179 PS00329 Heat shock hsp70 proteins family signature 2. 413999013180 PS00297 Heat shock hsp70 proteins family signature 1. 413999013181 GrpE; Region: GrpE; pfam01025 413999013182 GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446 413999013183 dimer interface [polypeptide binding]; other site 413999013184 hsp70 (ATPase domain) interactions [polypeptide binding]; other site 413999013185 Pfam match to entry PF01025 GrpE, GrpE, score 216.6, E-value 3.9e-62 413999013186 PS01071 grpE protein signature. 413999013187 heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082 413999013188 HTH domain; Region: HTH_11; cl17392 413999013189 Pfam match to entry PF01628 HrcA, HrcA protein C terminal domain, score 214.4, E-value 1.8e-61 413999013190 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013191 coproporphyrinogen III oxidase; Provisional; Region: PRK05799 413999013192 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999013193 FeS/SAM binding site; other site 413999013194 HemN C-terminal domain; Region: HemN_C; pfam06969 413999013195 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 108.6, E-value 1.2e-29 413999013196 GTP-binding protein LepA; Provisional; Region: PRK05433 413999013197 LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890 413999013198 G1 box; other site 413999013199 putative GEF interaction site [polypeptide binding]; other site 413999013200 GTP/Mg2+ binding site [chemical binding]; other site 413999013201 Switch I region; other site 413999013202 G2 box; other site 413999013203 G3 box; other site 413999013204 Switch II region; other site 413999013205 G4 box; other site 413999013206 G5 box; other site 413999013207 lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699 413999013208 lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709 413999013209 GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421 413999013210 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus, score 143.9, E-value 3e-40 413999013211 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 48.3, E-value 1.7e-11 413999013212 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 245.4, E-value 8.5e-71 413999013213 PS00301 GTP-binding elongation factors signature. 413999013214 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013215 1 probable transmembrane helix predicted for CBO2964 by TMHMM2.0 at aa 20-39 413999013216 Stage II sporulation protein P (SpoIIP); Region: SpoIIP; pfam07454 413999013217 stage II sporulation protein P; Region: spore_II_P; TIGR02867 413999013218 1 probable transmembrane helix predicted for CBO2965 by TMHMM2.0 at aa 17-36 413999013219 germination protease; Provisional; Region: PRK12362 413999013220 Pfam match to entry PF03418 Peptidase_U3,Germination protease, score 303.8, E-value 2.1e-88 413999013221 30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239 413999013222 Pfam match to entry PF01649 Ribosomal_S20p,Ribosomal protein S20, score 96.9, E-value 4.2e-26 413999013223 DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574 413999013224 DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144 413999013225 Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658 413999013226 Competence protein; Region: Competence; pfam03772 413999013227 9 probable transmembrane helices predicted for CBO2969 by TMHMM2.0 at aa 5-39, 49-68, 192-211, 226-248,261-280, 337-359, 364-386, 401-421 and 428-450 413999013228 Pfam match to entry PF03772 Competence, Competence protein, score 95.8, E-value 8.9e-26 413999013229 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013230 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 413999013231 ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494 413999013232 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 413999013233 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 413999013234 10 probable transmembrane helices predicted for CBO2971 by TMHMM2.0 at aa 52-74, 79-98, 242-264, 277-299,678-697, 707-729, 750-767, 777-797, 810-832 and 842-860 413999013235 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase, score 95.7, E-value 9.5e-26 413999013236 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus, score 19.8, E-value 2.5e-05 413999013237 Protein of unknown function (DUF1538); Region: DUF1538; pfam07556 413999013238 Protein of unknown function (DUF1538); Region: DUF1538; pfam07556 413999013239 14 probable transmembrane helices predicted for CBO2972 by TMHMM2.0 at aa 13-35, 40-62, 82-104, 114-136,148-170, 174-196, 208-230, 264-286, 293-315, 335-357,373-395, 400-422, 429-446 and 461-483 413999013240 1 probable transmembrane helix predicted for CBO2973 by TMHMM2.0 at aa 7-24 413999013241 Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]; Region: SelB; COG3276 413999013242 SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171 413999013243 G1 box; other site 413999013244 putative GEF interaction site [polypeptide binding]; other site 413999013245 GTP/Mg2+ binding site [chemical binding]; other site 413999013246 Switch I region; other site 413999013247 G2 box; other site 413999013248 G3 box; other site 413999013249 Switch II region; other site 413999013250 G4 box; other site 413999013251 G5 box; other site 413999013252 selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696 413999013253 This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094 413999013254 Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106 413999013255 Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107 413999013256 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 72.0, E-value 1.3e-18 413999013257 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 152.4, E-value 8.2e-43 413999013258 PS00301 GTP-binding elongation factors signature. 413999013259 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013260 seryl-tRNA(sec) selenium transferase; Region: selA; TIGR00474 413999013261 Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390 413999013262 Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921 413999013263 Pfam match to entry PF03841 SelA, L-seryl-tRNA selenium transferase, score 675.0, E-value 3.9e-200 413999013264 selenophosphate synthetase; Provisional; Region: PRK00943 413999013265 Selenophosphate synthetase (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195 413999013266 dimerization interface [polypeptide binding]; other site 413999013267 putative ATP binding site [chemical binding]; other site 413999013268 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain, score 66.5, E-value 6e-17 413999013269 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013270 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain, score 70.1, E-value 4.9e-18 413999013271 SLBB domain; Region: SLBB; pfam10531 413999013272 Helix-hairpin-helix motif; Region: HHH; pfam00633 413999013273 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 6.5, E-value 1 413999013274 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 33.9, E-value 4e-07 413999013275 1 probable transmembrane helix predicted for CBO2978 by TMHMM2.0 at aa 7-26 413999013276 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 413999013277 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768 413999013278 1 probable transmembrane helix predicted for CBO2979 by TMHMM2.0 at aa 3-25 413999013279 Pfam match to entry PF00768 Peptidase_S11,D-alanyl-D-alanine carboxypeptidase, score 239.2, E-value 6.2e-69 413999013280 Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain, score 20.5, E-value 1.6e-05 413999013281 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 413999013282 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999013283 RNA binding surface [nucleotide binding]; other site 413999013284 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 413999013285 active site 413999013286 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase, score 181.9, E-value 1.1e-51 413999013287 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 413999013288 homotrimer interaction site [polypeptide binding]; other site 413999013289 putative active site [active] 413999013290 Pfam match to entry PF01042 ribonuc_L-PSP,Endoribonuclease L-PSP, score 223.3, E-value 3.7e-64 413999013291 PS01094 Uncharacterized protein family UPF0076 signature. 413999013292 Transcriptional regulator [Transcription]; Region: LytR; COG1316 413999013293 LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399 413999013294 Pfam match to entry PF03816 LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain, score 213.5, E-value 3.4e-61 413999013295 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999013296 Zn2+ binding site [ion binding]; other site 413999013297 Mg2+ binding site [ion binding]; other site 413999013298 Pfam match to entry PF01966 HD, HD domain, score 44.1, E-value 3.2e-10 413999013299 nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071 413999013300 Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165 413999013301 active site 413999013302 (T/H)XGH motif; other site 413999013303 Pfam match to entry PF01467 CTP_transf_2,Cytidylyltransferase, score 170.2, E-value 3.5e-48 413999013304 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534 413999013305 Pfam match to entry PF01985 CRS1_YhbY, CRS1 / YhbY domain, score 133.7, E-value 3.5e-37 413999013306 GTPase CgtA; Reviewed; Region: obgE; PRK12297 413999013307 GTP1/OBG; Region: GTP1_OBG; pfam01018 413999013308 Obg GTPase; Region: Obg; cd01898 413999013309 G1 box; other site 413999013310 GTP/Mg2+ binding site [chemical binding]; other site 413999013311 Switch I region; other site 413999013312 G2 box; other site 413999013313 G3 box; other site 413999013314 Switch II region; other site 413999013315 G4 box; other site 413999013316 G5 box; other site 413999013317 Domain of unknown function (DUF1967); Region: DUF1967; pfam09269 413999013318 Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG family, score 403.0, E-value 3e-118 413999013319 PS00905 GTP1/OBG family signature. 413999013320 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013321 50S ribosomal protein L27; Validated; Region: rpmA; PRK05435 413999013322 Pfam match to entry PF01016 Ribosomal_L27,Ribosomal L27 protein, score 184.2, E-value 2.2e-52 413999013323 PS00831 Ribosomal protein L27 signature. 413999013324 hypothetical protein; Provisional; Region: PRK14553 413999013325 Pfam match to entry PF04327 DUF464, Protein of unknown function (DUF464), score 115.2, E-value 1.3e-31 413999013326 50S ribosomal protein L21; Validated; Region: rplU; PRK05573 413999013327 Pfam match to entry PF00829 Ribosomal_L21p,Ribosomal prokaryotic L21 protein, score 182.9, E-value 5.3e-52 413999013328 PS01169 Ribosomal protein L21 signature. 413999013329 Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530 413999013330 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 413999013331 homodimer interface [polypeptide binding]; other site 413999013332 oligonucleotide binding site [chemical binding]; other site 413999013333 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013334 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 16.6, E-value 0.0012 413999013335 radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936 413999013336 Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; pfam10105 413999013337 radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960 413999013338 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999013339 FeS/SAM binding site; other site 413999013340 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 83.1, E-value 5.9e-22 413999013341 SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F...; Region: S2P-M50_SpoIVFB; cd06161 413999013342 Peptidase family M50; Region: Peptidase_M50; pfam02163 413999013343 active site 413999013344 putative substrate binding region [chemical binding]; other site 413999013345 Pfam match to entry PF02163 Peptidase_M50,Peptidase M50, score 79.6, E-value 6.8e-21 413999013346 5 probable transmembrane helices predicted for CBO2993 by TMHMM2.0 at aa 7-29, 44-63, 76-98, 103-125 and 146-168 413999013347 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999013348 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 413999013349 Peptidase family M23; Region: Peptidase_M23; pfam01551 413999013350 Pfam match to entry PF01551 Peptidase_M37,Peptidase M23/M37, score 104.3, E-value 2.5e-28 413999013351 1 probable transmembrane helix predicted for CBO2994 by TMHMM2.0 at aa 47-69 413999013352 rod shape-determining protein RodA; Region: rodA_shape; TIGR02210 413999013353 Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein, score 359.0, E-value 5.2e-105 413999013354 9 probable transmembrane helices predicted for CBO2995 by TMHMM2.0 at aa 15-37, 50-72, 77-94, 137-159,163-182, 189-211, 276-293, 305-327 and 342-364 413999013355 PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 413999013356 cell division topological specificity factor MinE; Provisional; Region: PRK13987 413999013357 Pfam match to entry PF03776 MinE, Septum formation topological specificity factor MinE, score 79.6, E-value 6.6e-21 413999013358 Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036 413999013359 CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656 413999013360 Switch I; other site 413999013361 Switch II; other site 413999013362 Pfam match to entry PF00991 ParA, ParA family ATPase, score 56.1, E-value 8.1e-14 413999013363 Pfam match to entry PF00142 fer4_NifH, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family, score 24.6, E-value 3.9e-07 413999013364 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013365 septum formation inhibitor; Reviewed; Region: minC; PRK00513 413999013366 Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775 413999013367 Pfam match to entry PF03775 MinC_C, Septum formation inhibitor MinC, C-terminal domain, score 137.4,E-value 2.7e-38 413999013368 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 413999013369 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 413999013370 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 413999013371 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 413999013372 Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain, score 143.4, E-value 4.3e-40 413999013373 PS00216 Sugar transport proteins signature 1. 413999013374 Pfam match to entry PF03717 PBP_dimer,Penicillin-binding Protein dimerisation domain, score 97.7, E-value 2.4e-26 413999013375 1 probable transmembrane helix predicted for CBO2999 by TMHMM2.0 at aa 13-32 413999013376 rod shape-determining protein MreD; Region: shape_MreD; TIGR03426 413999013377 Pfam match to entry PF04093 MreD, rod shape-determining protein MreD, score 51.1, E-value 2.5e-12 413999013378 4 probable transmembrane helices predicted for CBO3000 by TMHMM2.0 at aa 7-29, 73-95, 100-122 and 132-154 413999013379 rod shape-determining protein MreC; Provisional; Region: PRK13922 413999013380 rod shape-determining protein MreC; Region: MreC; pfam04085 413999013381 Pfam match to entry PF04085 MreC, rod shape-determining protein MreC, score 139.4, E-value 6.8e-39 413999013382 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013383 rod shape-determining protein MreB; Provisional; Region: PRK13927 413999013384 MreB and similar proteins; Region: MreB_like; cd10225 413999013385 nucleotide binding site [chemical binding]; other site 413999013386 Mg binding site [ion binding]; other site 413999013387 putative protofilament interaction site [polypeptide binding]; other site 413999013388 RodZ interaction site [polypeptide binding]; other site 413999013389 PS01259 Apoptosis regulator, Bcl-2 family BH3 domain signature. 413999013390 hypothetical protein; Reviewed; Region: PRK00024 413999013391 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 413999013392 helix-hairpin-helix signature motif; other site 413999013393 Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071 413999013394 MPN+ (JAMM) motif; other site 413999013395 Zinc-binding site [ion binding]; other site 413999013396 Pfam match to entry PF04002 RadC, RadC, DNA repair protein, score 212.8, E-value 5.4e-61 413999013397 PS01302 DNA repair protein radC family signature. 413999013398 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 21.1, E-value 0.0028 413999013399 Maf-like protein; Reviewed; Region: PRK00078 413999013400 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 413999013401 active site 413999013402 dimer interface [polypeptide binding]; other site 413999013403 Pfam match to entry PF02545 Maf, Maf-like protein,score 244.2, E-value 1.9e-70 413999013404 Domain of unknown function (DUF4321); Region: DUF4321; pfam14209 413999013405 2 probable transmembrane helices predicted for CBO3005 by TMHMM2.0 at aa 9-31 and 60-82 413999013406 1 probable transmembrane helix predicted for CBO3006 by TMHMM2.0 at aa 16-38 413999013407 Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420 413999013408 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 413999013409 Pfam match to entry PF02567 PhzC-PhzF, Phenazine biosynthesis-like protein, score -52.5, E-value 4.9e-05 413999013410 PS00070 Aldehyde dehydrogenases cysteine active site. 413999013411 hypothetical protein; Provisional; Region: PRK04435 413999013412 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393 413999013413 DNA-binding interface [nucleotide binding]; DNA binding site 413999013414 C-terminal ACT domain of a small (; 147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and related domains; Region: ACT_PheB-BS; cd04888 413999013415 Pfam match to entry PF01842 ACT, ACT domain, score 25.7, E-value 0.00011 413999013416 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 413999013417 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 413999013418 N-acetyl-D-glucosamine binding site [chemical binding]; other site 413999013419 catalytic residue [active] 413999013420 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain, score 127.8, E-value 2.1e-35 413999013421 1 probable transmembrane helix predicted for CBO3012 by TMHMM2.0 at aa 4-23 413999013422 Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022 413999013423 Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237 413999013424 CoA-binding site [chemical binding]; other site 413999013425 ATP-binding [chemical binding]; other site 413999013426 Pfam match to entry PF01121 CoaE, Dephospho-CoA kinase, score 168.5, E-value 1.2e-47 413999013427 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013428 DNA polymerase I; Provisional; Region: PRK05755 413999013429 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 413999013430 active site 413999013431 metal binding site 1 [ion binding]; metal-binding site 413999013432 putative 5' ssDNA interaction site; other site 413999013433 metal binding site 3; metal-binding site 413999013434 metal binding site 2 [ion binding]; metal-binding site 413999013435 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 413999013436 putative DNA binding site [nucleotide binding]; other site 413999013437 putative metal binding site [ion binding]; other site 413999013438 inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140 413999013439 Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637 413999013440 active site 413999013441 DNA binding site [nucleotide binding] 413999013442 catalytic site [active] 413999013443 Pfam match to entry PF00476 DNA_pol_A, DNA polymerase A, score 603.2, E-value 1.6e-178 413999013444 PS00447 DNA polymerase A signature. 413999013445 Pfam match to entry PF01612 3_5_exonuclease, 3'-5' exonuclease, score -26.1, E-value 0.0009 413999013446 Pfam match to entry PF01367 5_3_exonuclease, 5'-3' exonuclease, C-terminal SAM fold, score 158.9, E-value 9.3e-45 413999013447 Pfam match to entry PF02739 5_3_exonuc_N, 5'-3' exonuclease, N-terminal resolvase-like domain, score 277.3, E-value 2.1e-80 413999013448 Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082 413999013449 Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304 413999013450 Tetramer interface [polypeptide binding]; other site 413999013451 active site 413999013452 FMN-binding site [chemical binding]; other site 413999013453 Pfam match to entry PF01264 Chorismate_synt,Chorismate synthase, score 416.4, E-value 2.7e-122 413999013454 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999013455 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999013456 active site 413999013457 metal binding site [ion binding]; metal-binding site 413999013458 Bacterial SH3 domain; Region: SH3_3; pfam08239 413999013459 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 50.9, E-value 2.9e-12 413999013460 2 probable transmembrane helices predicted for CBO3017 by TMHMM2.0 at aa 13-32 and 36-53 413999013461 Haemolysin XhlA; Region: XhlA; pfam10779 413999013462 1 probable transmembrane helix predicted for CBO3018 by TMHMM2.0 at aa 61-83 413999013463 possible genomic island which is highly in Clostridium tetani but absent from C. perfringens and C. acetobutylicum 413999013464 Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385 413999013465 Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042 413999013466 Caspase domain; Region: Peptidase_C14; pfam00656 413999013467 DivIVA protein; Region: DivIVA; pfam05103 413999013468 2 probable transmembrane helices predicted for CBO3032 by TMHMM2.0 at aa 178-200 and 220-242 413999013469 possible remnant of an integrated prophage 413999013470 hypothetical protein; Validated; Region: PRK08116 413999013471 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999013472 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 413999013473 Walker A motif; other site 413999013474 ATP binding site [chemical binding]; other site 413999013475 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013476 N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; pfam09681 413999013477 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 413999013478 non-specific DNA binding site [nucleotide binding]; other site 413999013479 salt bridge; other site 413999013480 sequence-specific DNA binding site [nucleotide binding]; other site 413999013481 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 27.8, E-value 2.6e-05 413999013482 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999013483 non-specific DNA binding site [nucleotide binding]; other site 413999013484 salt bridge; other site 413999013485 sequence-specific DNA binding site [nucleotide binding]; other site 413999013486 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 46.3, E-value 7.2e-11 413999013487 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 413999013488 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999013489 non-specific DNA binding site [nucleotide binding]; other site 413999013490 salt bridge; other site 413999013491 sequence-specific DNA binding site [nucleotide binding]; other site 413999013492 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 62.3, E-value 1.1e-15 413999013493 Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696 413999013494 7 probable transmembrane helices predicted for CBO3046 by TMHMM2.0 at aa 9-31, 46-64, 84-106, 327-349,370-392, 432-449 and 461-483 413999013495 Pfam match to entry PF03062 MBOAT, MBOAT family,score 212.7, E-value 6e-61 413999013496 1 probable transmembrane helix predicted for CBO3047 by TMHMM2.0 at aa 5-27 413999013497 Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269 413999013498 Pfam match to entry PF00269 SASP, Small,acid-soluble spore proteins, alpha/beta type, score 89.6,E-value 6.8e-24 413999013499 PS00684 Small, acid-soluble spore proteins,alpha/beta type, signature 2. 413999013500 PS00304 Small, acid-soluble spore proteins,alpha/beta type, signature 1. 413999013501 Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246 413999013502 Pfam match to entry PF04246 RseC_MucC, Positive regulator of sigma(E), RseC/MucC, score -1.2, E-value 0.00011 413999013503 2 probable transmembrane helices predicted for CBO3053 by TMHMM2.0 at aa 70-92 and 102-119 413999013504 aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476 413999013505 EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317 413999013506 dimer interface [polypeptide binding]; other site 413999013507 anticodon binding site; other site 413999013508 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 413999013509 homodimer interface [polypeptide binding]; other site 413999013510 motif 1; other site 413999013511 active site 413999013512 motif 2; other site 413999013513 GAD domain; Region: GAD; pfam02938 413999013514 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 413999013515 motif 3; other site 413999013516 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N), score 69.5, E-value 7.6e-18 413999013517 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999013518 Pfam match to entry PF02938 GAD, GAD domain, score 116.6, E-value 5.1e-32 413999013519 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999013520 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 76.2, E-value 7e-20 413999013521 histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037 413999013522 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 413999013523 dimer interface [polypeptide binding]; other site 413999013524 motif 1; other site 413999013525 active site 413999013526 motif 2; other site 413999013527 motif 3; other site 413999013528 HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859 413999013529 anticodon binding site; other site 413999013530 Pfam match to entry PF03129 HGTP_anticodon,Anticodon binding domain, score 63.3, E-value 5.4e-16 413999013531 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score 134.8, E-value 1.7e-37 413999013532 coproporphyrinogen III oxidase; Provisional; Region: PRK08207 413999013533 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999013534 FeS/SAM binding site; other site 413999013535 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 99.9, E-value 5.4e-27 413999013536 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 413999013537 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 127.9, E-value 1.9e-35 413999013538 D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563 413999013539 putative active site [active] 413999013540 dimerization interface [polypeptide binding]; other site 413999013541 putative tRNAtyr binding site [nucleotide binding]; other site 413999013542 Pfam match to entry PF02580 Tyr_Deacylase,D-Tyr-tRNA(Tyr) deacylase, score 249.7, E-value 4.2e-72 413999013543 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 413999013544 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999013545 Zn2+ binding site [ion binding]; other site 413999013546 Mg2+ binding site [ion binding]; other site 413999013547 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 413999013548 synthetase active site [active] 413999013549 NTP binding site [chemical binding]; other site 413999013550 metal binding site [ion binding]; metal-binding site 413999013551 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 413999013552 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 413999013553 Pfam match to entry PF02824 TGS, TGS domain, score 118.8, E-value 1.1e-32 413999013554 Pfam match to entry PF04607 RelA_SpoT, Region found in RelA / SpoT proteins, score 254.0, E-value 2.1e-73 413999013555 Pfam match to entry PF01966 HD, HD domain, score 66.0, E-value 8.6e-17 413999013556 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999013557 active site 413999013558 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 176.5, E-value 4.5e-50 413999013559 PS00144 Asparaginase / glutaminase active site signature 1. 413999013560 DHH family; Region: DHH; pfam01368 413999013561 Pfam match to entry PF01368 DHH, DHH family, score 67.6, E-value 2.8e-17 413999013562 preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022 413999013563 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 413999013564 Protein export membrane protein; Region: SecD_SecF; pfam02355 413999013565 Pfam match to entry PF02355 SecD_SecF, Protein export membrane protein, score 318.3, E-value 9.7e-93 413999013566 6 probable transmembrane helices predicted for CBO3062 by TMHMM2.0 at aa 9-27, 125-144, 146-168, 178-200,228-245 and 255-277 413999013567 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013568 protein-export membrane protein SecD; Region: secD; TIGR01129 413999013569 protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916 413999013570 Pfam match to entry PF02355 SecD_SecF, Protein export membrane protein, score -56.1, E-value 1.6e-06 413999013571 6 probable transmembrane helices predicted for CBO3063 by TMHMM2.0 at aa 13-35, 249-271, 278-297,302-324, 345-367 and 377-399 413999013572 SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974 413999013573 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999013574 FeS/SAM binding site; other site 413999013575 radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085 413999013576 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 56.7, E-value 5.3e-14 413999013577 PS01305 moaA / nifB / pqqE family signature. 413999013578 Protein of unknown function (DUF4001); Region: DUF4001; pfam13165 413999013579 Protein of unknown function (DUF3792); Region: DUF3792; pfam12670 413999013580 4 probable transmembrane helices predicted for CBO3066 by TMHMM2.0 at aa 12-34, 44-63, 70-92 and 102-121 413999013581 preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585 413999013582 Pfam match to entry PF02699 YajC, Preprotein translocase subunit, score 62.2, E-value 1.2e-15 413999013583 1 probable transmembrane helix predicted for CBO3067 by TMHMM2.0 at aa 4-26 413999013584 queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112 413999013585 Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343 413999013586 Pfam match to entry PF01702 TGT, Queuine tRNA-ribosyltransferase, score 400.5, E-value 1.7e-117 413999013587 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147 413999013588 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113 413999013589 PS00697 ATP-dependent DNA ligase AMP-binding site. 413999013590 Pfam match to entry PF02547 Queuosine_synth,Queuosine biosynthesis protein, score 407.7, E-value 1.2e-119 413999013591 Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080 413999013592 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999013593 Walker A motif; other site 413999013594 ATP binding site [chemical binding]; other site 413999013595 Walker B motif; other site 413999013596 arginine finger; other site 413999013597 Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491 413999013598 Pfam match to entry PF05491 RuvB_C, Holliday junction DNA helicase ruvB C-terminus, score 189.1,E-value 7.6e-54 413999013599 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 108.4, E-value 1.4e-29 413999013600 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013601 Pfam match to entry PF05496 RuvB_N, Holliday junction DNA helicase ruvB N-terminus, score 87.6, E-value 2.7e-23 413999013602 Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116 413999013603 RuvA N terminal domain; Region: RuvA_N; pfam01330 413999013604 RuvA, C-terminal domain; Region: RuvA_C; pfam07499 413999013605 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 15.8, E-value 0.077 413999013606 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 4.2, E-value 1.9 413999013607 Pfam match to entry PF01330 RuvA, RuvA N terminal domain, score 91.6, E-value 1.7e-24 413999013608 1 probable transmembrane helix predicted for CBO3072 by TMHMM2.0 at aa 7-26 413999013609 hypothetical protein; Validated; Region: PRK00110 413999013610 Pfam match to entry PF01709 DUF28, Domain of unknown function DUF28, score 509.2, E-value 3.2e-150 413999013611 Uncharacterized conserved protein [Function unknown]; Region: COG1739 413999013612 Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205 413999013613 Domain of unknown function (DUF1949); Region: DUF1949; pfam09186 413999013614 Pfam match to entry PF01205 UPF0029,Uncharacterized protein family UPF0029, score 197.4,E-value 2.3e-56 413999013615 PS00910 Uncharacterized protein family UPF0029 signature. 413999013616 HEAT repeats; Region: HEAT_2; pfam13646 413999013617 HEAT-like repeat; Region: HEAT_EZ; pfam13513 413999013618 Pfam match to entry PF03130 HEAT_PBS, PBS lyase HEAT-like repeat, score 22.8, E-value 0.00083 413999013619 Pfam match to entry PF03130 HEAT_PBS, PBS lyase HEAT-like repeat, score 19.9, E-value 0.0063 413999013620 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 413999013621 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 413999013622 DNA-binding site [nucleotide binding]; DNA binding site 413999013623 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999013624 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999013625 homodimer interface [polypeptide binding]; other site 413999013626 catalytic residue [active] 413999013627 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family, score 31.5, E-value 2e-06 413999013628 PS00043 Bacterial regulatory proteins, gntR family signature. 413999013629 Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403 413999013630 active site 413999013631 NTP binding site [chemical binding]; other site 413999013632 metal binding triad [ion binding]; metal-binding site 413999013633 antibiotic binding site [chemical binding]; other site 413999013634 Pfam match to entry PF01909 NTP_transf_2,Nucleotidyltransferase domain, score 40.2, E-value 5e-09 413999013635 Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730 413999013636 Rubredoxin; Region: Rubredoxin; pfam00301 413999013637 iron binding site [ion binding]; other site 413999013638 Pfam match to entry PF00301 rubredoxin, Rubredoxin,score 114.6, E-value 2e-31 413999013639 PS00202 Rubredoxin signature. 413999013640 GTP-binding protein HflX; Region: GTP_HflX; TIGR03156 413999013641 GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167 413999013642 HflX GTPase family; Region: HflX; cd01878 413999013643 G1 box; other site 413999013644 GTP/Mg2+ binding site [chemical binding]; other site 413999013645 Switch I region; other site 413999013646 G2 box; other site 413999013647 G3 box; other site 413999013648 Switch II region; other site 413999013649 G4 box; other site 413999013650 G5 box; other site 413999013651 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013652 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999013653 active site 413999013654 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 104.5, E-value 2.1e-28 413999013655 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 413999013656 Sporulation protein YunB (Spo_YunB); Region: Spore_YunB; cl09783 413999013657 Transglycosylase; Region: Transgly; pfam00912 413999013658 penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074 413999013659 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 413999013660 1 probable transmembrane helix predicted for CBO3083 by TMHMM2.0 at aa 13-35 413999013661 Pfam match to entry PF00912 Transglycosyl,Transglycosylase, score 239.9, E-value 3.8e-69 413999013662 Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain, score 108.1, E-value 1.8e-29 413999013663 stage V sporulation protein AE; Region: spore_V_AE; TIGR02839 413999013664 Pfam match to entry PF03862 spoVA, SpoVA protein,score 69.6, E-value 7.1e-18 413999013665 3 probable transmembrane helices predicted for CBO3084 by TMHMM2.0 at aa 3-20, 30-52 and 89-111 413999013666 stage V sporulation protein AD; Validated; Region: PRK08304 413999013667 stage V sporulation protein AD; Provisional; Region: PRK12404 413999013668 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013669 SpoVA protein; Region: SpoVA; cl04298 413999013670 Pfam match to entry PF03862 spoVA, SpoVA protein,score 122.6, E-value 7.5e-34 413999013671 4 probable transmembrane helices predicted for CBO3086 by TMHMM2.0 at aa 30-52, 62-81, 88-110 and 125-147 413999013672 sporulation sigma factor SigF; Validated; Region: PRK05572 413999013673 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999013674 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 413999013675 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 413999013676 DNA binding residues [nucleotide binding] 413999013677 Pfam match to entry PF04545 sigma70_r4, Sigma-70,region 4, score 55.4, E-value 1.3e-13 413999013678 PS00716 Sigma-70 factors family signature 2. 413999013679 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 63.8, E-value 3.8e-16 413999013680 PS00715 Sigma-70 factors family signature 1. 413999013681 anti-sigma F factor; Provisional; Region: PRK03660 413999013682 Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172 413999013683 ATP binding site [chemical binding]; other site 413999013684 Mg2+ binding site [ion binding]; other site 413999013685 G-X-G motif; other site 413999013686 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 63.9,E-value 3.6e-16 413999013687 Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043 413999013688 anti sigma factor interaction site; other site 413999013689 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 413999013690 regulatory phosphorylation site [posttranslational modification]; other site 413999013691 Pfam match to entry PF01740 STAS, STAS domain,score 116.3, E-value 6.1e-32 413999013692 TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950 413999013693 Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948 413999013694 delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884 413999013695 NodB motif; other site 413999013696 active site 413999013697 catalytic site [active] 413999013698 Cd binding site [ion binding]; other site 413999013699 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013700 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 147.1, E-value 3.3e-41 413999013701 capsular polysaccharide biosynthsis gene cluster 413999013702 Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922 413999013703 The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533 413999013704 Pfam match to entry PF03808 Glyco_tran_WecB,Glycosyl transferase WecB/TagA/CpsF family, score 253.2,E-value 3.7e-73 413999013705 Bacterial sugar transferase; Region: Bac_transf; pfam02397 413999013706 Pfam match to entry PF02397 Bact_transf, Bacterial sugar transferase, score 260.6, E-value 2.2e-75 413999013707 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013708 1 probable transmembrane helix predicted for CBO3093 by TMHMM2.0 at aa 28-50 413999013709 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 413999013710 Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128 413999013711 14 probable transmembrane helices predicted for CBO3094 by TMHMM2.0 at aa 13-35, 45-67, 80-102, 117-139,148-170, 180-202, 215-234, 249-271, 292-310, 320-342,355-377, 382-404, 411-433 and 437-454 413999013712 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 38.5, E-value 1.6e-08 413999013713 PS00037 Myb DNA-binding domain repeat signature 1. 413999013714 PS00027 'Homeobox' domain signature. 413999013715 Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728 413999013716 MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123 413999013717 14 probable transmembrane helices predicted for CBO3095 by TMHMM2.0 at aa 9-31, 46-68, 92-114, 129-151,158-180, 185-204, 235-257, 272-294, 306-328, 348-370,383-400, 404-426, 439-461 and 476-498 413999013718 Pfam match to entry PF03023 MVIN, MviN-like protein, score 294.8, E-value 1.1e-85 413999013719 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 5.7, E-value 6e-05 413999013720 Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439 413999013721 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 413999013722 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999013723 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 135.3, E-value 1.1e-37 413999013724 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999013725 This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798 413999013726 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 141.3, E-value 1.8e-39 413999013727 Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307 413999013728 O-Antigen ligase; Region: Wzy_C; pfam04932 413999013729 10 probable transmembrane helices predicted for CBO3098 by TMHMM2.0 at aa 7-24, 37-54, 67-89, 99-118,130-152, 172-189, 198-220, 230-252, 330-347 and 367-386 413999013730 Pfam match to entry PF04932 Wzy_C, O-Antigen Polymerase, score 69.8, E-value 5.9e-18 413999013731 This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794 413999013732 putative glycosyl transferase; Provisional; Region: PRK10307 413999013733 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 68.5, E-value 1.5e-17 413999013734 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 413999013735 active site 413999013736 UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350 413999013737 homodimer interface [polypeptide binding]; other site 413999013738 Pfam match to entry PF02350 Epimerase_2,UDP-N-acetylglucosamine 2-epimerase, score 478.7, E-value 5e-141 413999013739 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013740 This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798 413999013741 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999013742 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 186.0, E-value 6.5e-53 413999013743 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 413999013744 12 probable transmembrane helices predicted for CBO3103 by TMHMM2.0 at aa 2-19, 34-56, 77-99, 119-140,179-196, 206-223, 228-247, 252-271, 284-306, 366-388,395-414 and 418-440 413999013745 PS00043 Bacterial regulatory proteins, gntR family signature. 413999013746 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013747 Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309 413999013748 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999013749 Leucine-rich repeats; other site 413999013750 Substrate binding site [chemical binding]; other site 413999013751 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999013752 Leucine rich repeat; Region: LRR_8; pfam13855 413999013753 Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799 413999013754 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 15.7, E-value 0.11 413999013755 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 13.5, E-value 0.53 413999013756 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 18.9, E-value 0.012 413999013757 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 10.2, E-value 4.4 413999013758 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 9.7, E-value 5.2 413999013759 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 11.8, E-value 1.8 413999013760 Pfam match to entry PF00560 LRR, Leucine Rich Repeat, score 18.0, E-value 0.024 413999013761 1 probable transmembrane helix predicted for CBO3104 by TMHMM2.0 at aa 16-33 413999013762 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 413999013763 Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128 413999013764 12 probable transmembrane helices predicted for CBO3105 by TMHMM2.0 at aa 7-29, 39-61, 81-98, 113-135,147-164, 168-187, 207-226, 246-268, 288-310, 320-342,349-371 and 375-397 413999013765 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 51.4, E-value 2.1e-12 413999013766 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 413999013767 putative trimer interface [polypeptide binding]; other site 413999013768 putative CoA binding site [chemical binding]; other site 413999013769 WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358 413999013770 putative trimer interface [polypeptide binding]; other site 413999013771 putative active site [active] 413999013772 putative substrate binding site [chemical binding]; other site 413999013773 putative CoA binding site [chemical binding]; other site 413999013774 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 11.1,E-value 2.8 413999013775 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 0.8,E-value 78 413999013776 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.4,E-value 4.5 413999013777 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 19.2,E-value 0.01 413999013778 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 7.0,E-value 14 413999013779 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 5.0,E-value 24 413999013780 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 19.8,E-value 0.0069 413999013781 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 20.8,E-value 0.0035 413999013782 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 13.2,E-value 0.65 413999013783 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 413999013784 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 413999013785 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 413999013786 Pfam match to entry PF02894 GFO_IDH_MocA_C,Oxidoreductase, C-terminal alpha/beta domain, score 42.0, E-value 1.4e-09 413999013787 Pfam match to entry PF01408 GFO_IDH_MocA,Oxidoreductase, NAD-binding Rossmann fold, score 127.0, E-value 3.7e-35 413999013788 UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677 413999013789 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 413999013790 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 413999013791 Pfam match to entry PF03720 UDPG_MGDP_dh_C,UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain, score 59.5, E-value 7.4e-15 413999013792 Pfam match to entry PF00984 UDPG_MGDP_dh,UDP-glucose/GDP-mannose dehydrogenase, central domain, score 122.5, E-value 8.1e-34 413999013793 Pfam match to entry PF03721 UDPG_MGDP_dh_N,UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain, score 206.2, E-value 5.2e-59 413999013794 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 413999013795 Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719 413999013796 NAD(P) binding site [chemical binding]; other site 413999013797 homodimer interface [polypeptide binding]; other site 413999013798 substrate binding site [chemical binding]; other site 413999013799 active site 413999013800 Pfam match to entry PF02719 Polysacc_synt_2,Polysaccharide biosynthesis protein, score 771.1, E-value 4.7e-229 413999013801 4 probable transmembrane helices predicted for CBO3109 by TMHMM2.0 at aa 7-26, 41-60, 80-99 and 112-134 413999013802 triple tyrosine motif-containing protein; Provisional; Region: PRK14081 413999013803 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999013804 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999013805 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999013806 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999013807 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999013808 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999013809 active site 413999013810 metal binding site [ion binding]; metal-binding site 413999013811 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 94.3, E-value 2.6e-25 413999013812 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013813 1 probable transmembrane helix predicted for CBO3110 by TMHMM2.0 at aa 13-35 413999013814 triple tyrosine motif-containing protein; Provisional; Region: PRK14081 413999013815 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999013816 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999013817 active site 413999013818 metal binding site [ion binding]; metal-binding site 413999013819 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 153.5, E-value 3.9e-43 413999013820 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013821 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013822 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013823 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013824 1 probable transmembrane helix predicted for CBO3111 by TMHMM2.0 at aa 12-29 413999013825 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 413999013826 dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209 413999013827 active site 413999013828 tetramer interface; other site 413999013829 Pfam match to entry PF00483 NTP_transferase,Nucleotidyl transferase, score 91.2, E-value 2.2e-24 413999013830 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999013831 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999013832 binding surface 413999013833 TPR motif; other site 413999013834 Pfam match to entry PF00515 TPR, TPR Domain, score 4.4, E-value 1.1 413999013835 Pfam match to entry PF00515 TPR, TPR Domain, score 15.9, E-value 0.047 413999013836 Pfam match to entry PF00515 TPR, TPR Domain, score 30.8, E-value 3.3e-06 413999013837 phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150 413999013838 This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799 413999013839 active site 413999013840 substrate binding site [chemical binding]; other site 413999013841 metal binding site [ion binding]; metal-binding site 413999013842 Pfam match to entry PF00408 PGM_PMM,Phosphoglucomutase/phosphomannomutase, C-terminal domain,score 4.4, E-value 0.005 413999013843 Pfam match to entry PF02880 PGM_PMM_III,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III, score 10.2, E-value 0.0035 413999013844 Pfam match to entry PF02879 PGM_PMM_II,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II, score -10.9, E-value 0.011 413999013845 Pfam match to entry PF02878 PGM_PMM_I,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I, score 173.6, E-value 3.3e-49 413999013846 50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618 413999013847 Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495 413999013848 5S rRNA interface [nucleotide binding]; other site 413999013849 CTC domain interface [polypeptide binding]; other site 413999013850 L16 interface [polypeptide binding]; other site 413999013851 Pfam match to entry PF01386 Ribosomal_L25p,Ribosomal L25p family, score 50.6, E-value 3.5e-12 413999013852 Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982 413999013853 Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615 413999013854 homodimer interface [polypeptide binding]; other site 413999013855 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999013856 catalytic residue [active] 413999013857 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 413999013858 Pfam match to entry PF01276 OKR_DC_1, Orn/Lys/Arg decarboxylase, major domain, score 461.6, E-value 6.8e-136 413999013859 Pfam match to entry PF03711 OKR_DC_1_C, Orn/Lys/Arg decarboxylase, C-terminal domain, score 9.9, E-value 4.1e-05 413999013860 Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212 413999013861 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999013862 Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase, score 167.1, E-value 3e-47 413999013863 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999013864 Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809 413999013865 active site 413999013866 substrate binding site [chemical binding]; other site 413999013867 FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070 413999013868 FMN binding site [chemical binding]; other site 413999013869 putative catalytic residues [active] 413999013870 Pfam match to entry PF01070 FMN_dh, FMN-dependent dehydrogenase, score 91.3, E-value 2e-24 413999013871 PS00912 Dihydroorotate dehydrogenase signature 2. 413999013872 Uncharacterized conserved protein [Function unknown]; Region: COG1683 413999013873 Pfam match to entry PF04463 DUF523, Protein of unknown function (DUF523), score 208.8, E-value 8.8e-60 413999013874 recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409 413999013875 MutS domain III; Region: MutS_III; pfam05192 413999013876 ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280 413999013877 Walker A/P-loop; other site 413999013878 ATP binding site [chemical binding]; other site 413999013879 Q-loop/lid; other site 413999013880 ABC transporter signature motif; other site 413999013881 Walker B; other site 413999013882 D-loop; other site 413999013883 H-loop/switch region; other site 413999013884 Smr domain; Region: Smr; pfam01713 413999013885 Pfam match to entry PF01713 Smr, Smr domain, score 111.5, E-value 1.7e-30 413999013886 Pfam match to entry PF00488 MutS_V, MutS domain V,score 22.2, E-value 1.5e-15 413999013887 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013888 Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826 413999013889 Peptidase family U32; Region: Peptidase_U32; pfam01136 413999013890 Collagenase; Region: DUF3656; pfam12392 413999013891 Peptidase family U32; Region: Peptidase_U32; cl03113 413999013892 Pfam match to entry PF01136 Peptidase_U32,Peptidase U32, score 411.2, E-value 1e-120 413999013893 PS01276 Peptidase U32 signature. 413999013894 Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942 413999013895 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 413999013896 Cell division protein ZapA; Region: ZapA; pfam05164 413999013897 Pfam match to entry PF05164 DUF710, Family of unknown function (DUF710), score 66.0, E-value 8.3e-17 413999013898 phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629 413999013899 tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796 413999013900 putative tRNA-binding site [nucleotide binding]; other site 413999013901 B3/4 domain; Region: B3_4; pfam03483 413999013902 tRNA synthetase B5 domain; Region: B5; smart00874 413999013903 Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an...; Region: PheRS_beta_core; cd00769 413999013904 dimer interface [polypeptide binding]; other site 413999013905 motif 1; other site 413999013906 motif 3; other site 413999013907 motif 2; other site 413999013908 Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896 413999013909 Pfam match to entry PF03147 FDX-ACB,Ferredoxin-fold anticodon binding domain, score 158.3,E-value 1.4e-44 413999013910 Pfam match to entry PF03484 B5, tRNA synthetase B5 domain, score 99.3, E-value 7.8e-27 413999013911 Pfam match to entry PF03483 B3_4, B3/4 domain,score 236.7, E-value 3.6e-68 413999013912 Pfam match to entry PF01588 tRNA_bind, tRNA binding domain, score 91.4, E-value 1.8e-24 413999013913 phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488 413999013914 Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912 413999013915 Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496 413999013916 dimer interface [polypeptide binding]; other site 413999013917 motif 1; other site 413999013918 active site 413999013919 motif 2; other site 413999013920 motif 3; other site 413999013921 Pfam match to entry PF01409 tRNA-synt_2d, tRNA synthetases class II core domain (F), score 500.3, E-value 1.5e-147 413999013922 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999013923 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999013924 Pfam match to entry PF02912 Phe_tRNA-synt_N,Aminoacyl tRNA synthetase class II, N-terminal domain,score 68.5, E-value 1.5e-17 413999013925 rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566 413999013926 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967 413999013927 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 413999013928 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase, score 108.4, E-value 1.4e-29 413999013929 K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569 413999013930 TrkA-N domain; Region: TrkA_N; pfam02254 413999013931 TrkA-C domain; Region: TrkA_C; pfam02080 413999013932 Pfam match to entry PF02080 TrkA-C, TrkA-C domain,score 68.5, E-value 1.5e-17 413999013933 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 413999013934 Pfam match to entry PF02254 TrkA-N, TrkA-N domain,score 158.4, E-value 1.3e-44 413999013935 Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168 413999013936 potassium uptake protein, TrkH family; Region: 2a38; TIGR00933 413999013937 Pfam match to entry PF02386 TrkH, Cation transport protein, score 295.7, E-value 6.2e-86 413999013938 8 probable transmembrane helices predicted for CBO3134 by TMHMM2.0 at aa 13-35, 77-99, 130-152, 191-213,230-249, 296-330, 347-369 and 389-411 413999013939 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999013940 Ribosomal protein L20; Region: Ribosomal_L20; cd07026 413999013941 23S rRNA binding site [nucleotide binding]; other site 413999013942 L21 binding site [polypeptide binding]; other site 413999013943 L13 binding site [polypeptide binding]; other site 413999013944 Pfam match to entry PF00453 Ribosomal_L20,Ribosomal protein L20, score 195.0, E-value 1.2e-55 413999013945 PS00937 Ribosomal protein L20 signature. 413999013946 50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172 413999013947 Pfam match to entry PF01632 Ribosomal_L35p,Ribosomal protein L35, score 88.5, E-value 1.4e-23 413999013948 PS00936 Ribosomal protein L35 signature. 413999013949 translation initiation factor IF-3; Reviewed; Region: infC; PRK00028 413999013950 Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198 413999013951 Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707 413999013952 Pfam match to entry PF00707 IF3_C, Translation initiation factor IF-3, C-terminal domain, score 155.7,E-value 8.2e-44 413999013953 Pfam match to entry PF05198 IF3_N, Translation initiation factor IF-3, N-terminal domain, score 72.4,E-value 9.8e-19 413999013954 PS00938 Initiation factor 3 signature. 413999013955 threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413 413999013956 TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667 413999013957 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 413999013958 Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771 413999013959 active site 413999013960 dimer interface [polypeptide binding]; other site 413999013961 motif 1; other site 413999013962 motif 2; other site 413999013963 motif 3; other site 413999013964 ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860 413999013965 anticodon binding site; other site 413999013966 Pfam match to entry PF03129 HGTP_anticodon,Anticodon binding domain, score 140.6, E-value 2.9e-39 413999013967 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score 186.4, E-value 4.7e-53 413999013968 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999013969 Pfam match to entry PF02824 TGS, TGS domain, score 43.5, E-value 4.9e-10 413999013970 YtxC-like family; Region: YtxC; pfam08812 413999013971 12 probable transmembrane helices predicted for CBO3141 by TMHMM2.0 at aa 26-43, 58-77, 104-126, 141-163,175-193, 203-225, 237-259, 322-344, 351-373, 424-446,459-481 and 491-513 413999013972 ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555 413999013973 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 413999013974 Walker A/P-loop; other site 413999013975 ATP binding site [chemical binding]; other site 413999013976 Q-loop/lid; other site 413999013977 ABC transporter signature motif; other site 413999013978 Walker B; other site 413999013979 D-loop; other site 413999013980 H-loop/switch region; other site 413999013981 Pfam match to entry PF00005 ABC_tran, ABC transporter score 170.5, E-value 3e-48 413999013982 PS00211 ABC transporters family signature. 413999013983 PS00017 ATP/GTP-binding site motif A (P-loop). 413999013984 Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114 413999013985 Heat shock protein 33 (Hsp33): Cytosolic protein that acts as a molecular chaperone under oxidative conditions. In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498 413999013986 dimerization interface [polypeptide binding]; other site 413999013987 domain crossover interface; other site 413999013988 redox-dependent activation switch; other site 413999013989 Pfam match to entry PF01430 HSP33, Hsp33 protein,score 473.9, E-value 1.3e-139 413999013990 SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500 413999013991 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999013992 S-adenosylmethionine binding site [chemical binding]; other site 413999013993 Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269 413999013994 Pfam match to entry PF00269 SASP, Small,acid-soluble spore proteins, alpha/beta type, score 25.1,E-value 1.7e-06 413999013995 PS00304 Small, acid-soluble spore proteins,alpha/beta type, signature 1. 413999013996 ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608 413999013997 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 413999013998 Walker A/P-loop; other site 413999013999 ATP binding site [chemical binding]; other site 413999014000 Q-loop/lid; other site 413999014001 ABC transporter signature motif; other site 413999014002 Walker B; other site 413999014003 D-loop; other site 413999014004 H-loop/switch region; other site 413999014005 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 413999014006 Pfam match to entry PF00005 ABC_tran, ABC transporter score 200.8, E-value 2.3e-57 413999014007 PS00211 ABC transporters family signature. 413999014008 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014009 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444 413999014010 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 413999014011 Walker A/P-loop; other site 413999014012 ATP binding site [chemical binding]; other site 413999014013 Q-loop/lid; other site 413999014014 ABC transporter signature motif; other site 413999014015 Walker B; other site 413999014016 D-loop; other site 413999014017 H-loop/switch region; other site 413999014018 oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727 413999014019 Pfam match to entry PF00005 ABC_tran, ABC transporter score 222.5, E-value 6.7e-64 413999014020 PS00211 ABC transporters family signature. 413999014021 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014022 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 413999014023 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 413999014024 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999014025 putative PBP binding loops; other site 413999014026 dimer interface [polypeptide binding]; other site 413999014027 ABC-ATPase subunit interface; other site 413999014028 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 161.5, E-value 1.5e-45 413999014029 6 probable transmembrane helices predicted for CBO3148 by TMHMM2.0 at aa 42-64, 105-127, 140-162,166-185, 216-238 and 269-291 413999014030 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 413999014031 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999014032 dimer interface [polypeptide binding]; other site 413999014033 conserved gate region; other site 413999014034 putative PBP binding loops; other site 413999014035 ABC-ATPase subunit interface; other site 413999014036 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 203.4, E-value 3.8e-58 413999014037 6 probable transmembrane helices predicted for CBO3149 by TMHMM2.0 at aa 9-31, 100-122, 134-156, 166-188,227-249 and 277-299 413999014038 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 413999014039 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 413999014040 peptide binding site [polypeptide binding]; other site 413999014041 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, score 286.3, E-value 4.1e-83 413999014042 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999014043 aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874 413999014044 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 413999014045 Pfam match to entry PF01118 Semialdhyde_dh,Semialdehyde dehydrogenase, NAD binding domain, score 173.0, E-value 5.2e-49 413999014046 Pfam match to entry PF02774 Semialdhyde_dhC,Semialdehyde dehydrogenase, dimerisation domain, score 220.5, E-value 2.6e-63 413999014047 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 413999014048 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 413999014049 dimer interface [polypeptide binding]; other site 413999014050 active site 413999014051 catalytic residue [active] 413999014052 Pfam match to entry PF00701 DHDPS,Dihydrodipicolinate synthetase, score 363.0,E-value 3.3e-106 413999014053 PS00665 Dihydrodipicolinate synthetase signature 1. 413999014054 PS00583 pfkB family of carbohydrate kinases signature 1. 413999014055 PS00666 Dihydrodipicolinate synthetase signature 2. 413999014056 dihydrodipicolinate reductase; Provisional; Region: PRK00048 413999014057 Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113 413999014058 Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173 413999014059 Pfam match to entry PF01113 DapB_N,Dihydrodipicolinate reductase, N-terminus, score 128.1,E-value 1.7e-35 413999014060 Pfam match to entry PF05173 DapB_C,Dihydrodipicolinate reductase, C-terminus, score 213.0,E-value 4.9e-61 413999014061 PS01298 Dihydrodipicolinate reductase signature. 413999014062 aminotransferase A; Validated; Region: PRK07683 413999014063 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 413999014064 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999014065 homodimer interface [polypeptide binding]; other site 413999014066 catalytic residue [active] 413999014067 Pfam match to entry PF00155 aminotran_1_2,Aminotransferase class I and II, score 157.8, E-value 1.9e-44 413999014068 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 413999014069 Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503 413999014070 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532 413999014071 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350 413999014072 trimer interface [polypeptide binding]; other site 413999014073 active site 413999014074 substrate binding site [chemical binding]; other site 413999014075 CoA binding site [chemical binding]; other site 413999014076 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 14.7,E-value 0.24 413999014077 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 15.8,E-value 0.11 413999014078 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 8.6,E-value 8.9 413999014079 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 17.9,E-value 0.026 413999014080 PS00101 Hexapeptide-repeat containing-transferases signature. 413999014081 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.6,E-value 4 413999014082 single-stranded DNA-binding protein; Provisional; Region: PRK05813 413999014083 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 413999014084 dimer interface [polypeptide binding]; other site 413999014085 ssDNA binding site [nucleotide binding]; other site 413999014086 tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999014087 Pfam match to entry PF00436 SSB, Single-strand binding protein family, score 81.6, E-value 1.7e-21 413999014088 Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917 413999014089 NodB motif; other site 413999014090 active site 413999014091 catalytic site [active] 413999014092 metal binding site [ion binding]; metal-binding site 413999014093 Pfam match to entry PF01522 Polysacc_deacet,Polysaccharide deacetylase, score 156.8, E-value 4e-44 413999014094 1 probable transmembrane helix predicted for CBO3159 by TMHMM2.0 at aa 9-26 413999014095 Domain of unknown function (DUF4364); Region: DUF4364; pfam14277 413999014096 PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866 413999014097 uncharacterized protein TIGR03905; Region: TIGR03905_4_Cys 413999014098 Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285 413999014099 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999014100 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 413999014101 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain, score 46.8,E-value 5.1e-11 413999014102 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 63.4, E-value 4.9e-16 413999014103 PS01012 Folylpolyglutamate synthase signature 2. 413999014104 PS01011 Folylpolyglutamate synthase signature 1. 413999014105 valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729 413999014106 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 413999014107 active site 413999014108 HIGH motif; other site 413999014109 nucleotide binding site [chemical binding]; other site 413999014110 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 413999014111 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 413999014112 active site 413999014113 KMSKS motif; other site 413999014114 Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962 413999014115 tRNA binding surface [nucleotide binding]; other site 413999014116 anticodon binding site; other site 413999014117 Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458 413999014118 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V), score 878.7, E-value 1.8e-261 413999014119 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999014120 putative acetyltransferase YhhY; Provisional; Region: PRK10140 413999014121 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999014122 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 413999014123 Coenzyme A binding pocket [chemical binding]; other site 413999014124 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 83.6, E-value 4.3e-22 413999014125 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 413999014126 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 413999014127 Walker A/P-loop; other site 413999014128 ATP binding site [chemical binding]; other site 413999014129 Q-loop/lid; other site 413999014130 ABC transporter signature motif; other site 413999014131 Walker B; other site 413999014132 D-loop; other site 413999014133 H-loop/switch region; other site 413999014134 Pfam match to entry PF00005 ABC_tran, ABC transporter score 192.8, E-value 5.9e-55 413999014135 PS00211 ABC transporters family signature. 413999014136 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014137 8 probable transmembrane helices predicted for CBO3167 by TMHMM2.0 at aa 5-27, 37-59, 80-98, 108-130,160-182, 420-437, 473-492 and 512-534 413999014138 4 probable transmembrane helices predicted for CBO3168 by TMHMM2.0 at aa 7-24, 51-73, 80-102 and 112-129 413999014139 NMT1-like family; Region: NMT1_2; pfam13379 413999014140 NMT1/THI5 like; Region: NMT1; pfam09084 413999014141 Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; Region: CH; cl00030 413999014142 putative actin binding surface [polypeptide binding]; other site 413999014143 1 probable transmembrane helix predicted for CBO3169 by TMHMM2.0 at aa 7-24 413999014144 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999014145 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924 413999014146 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999014147 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580 413999014148 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999014149 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581 413999014150 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 99.0, E-value 9.6e-27 413999014151 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 28.7, E-value 2.6e-09 413999014152 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014153 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 413999014154 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 413999014155 Walker A/P-loop; other site 413999014156 ATP binding site [chemical binding]; other site 413999014157 Q-loop/lid; other site 413999014158 ABC transporter signature motif; other site 413999014159 Walker B; other site 413999014160 D-loop; other site 413999014161 H-loop/switch region; other site 413999014162 Pfam match to entry PF00005 ABC_tran, ABC transporter score 206.1, E-value 5.6e-59 413999014163 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014164 PS00211 ABC transporters family signature. 413999014165 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 413999014166 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 413999014167 dimer interface [polypeptide binding]; other site 413999014168 conserved gate region; other site 413999014169 putative PBP binding loops; other site 413999014170 ABC-ATPase subunit interface; other site 413999014171 6 probable transmembrane helices predicted for CBO3172 by TMHMM2.0 at aa 22-41, 79-101, 113-132, 137-159,180-202 and 235-257 413999014172 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 109.5, E-value 6.8e-30 413999014173 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999014174 TPR repeat; Region: TPR_11; pfam13414 413999014175 binding surface 413999014176 TPR motif; other site 413999014177 Pfam match to entry PF00515 TPR, TPR Domain, score 22.1, E-value 0.0014 413999014178 Pfam match to entry PF00515 TPR, TPR Domain, score 20.9, E-value 0.0032 413999014179 Pfam match to entry PF00515 TPR, TPR Domain, score 15.1, E-value 0.059 413999014180 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 413999014181 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 413999014182 Pfam match to entry PF01841 Transglut_core,Transglutaminase-like superfamily, score 49.0, E-value 1.1e-11 413999014183 4 probable transmembrane helices predicted for CBO3174 by TMHMM2.0 at aa 7-29, 44-63, 89-111 and 144-166 413999014184 recombination regulator RecX; Provisional; Region: recX; PRK14134 413999014185 Pfam match to entry PF02631 RecX, RecX family,score 17.6, E-value 0.00023 413999014186 Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612 413999014187 Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675 413999014188 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 413999014189 Pfam match to entry PF05193 Peptidase_M16_C,Peptidase M16 inactive domain, score 124.1, E-value 2.7e-34 413999014190 Pfam match to entry PF00675 Peptidase_M16,Insulinase (Peptidase M16), score 118.0, E-value 1.9e-32 413999014191 PS00143 Insulinase, zinc-binding region signature. 413999014192 QueT transporter; Region: QueT; pfam06177 413999014193 Pfam match to entry PF06177 DUF988, Protein of unknown function (DUF988), score 189.4, E-value 6.2e-54 413999014194 5 probable transmembrane helices predicted for CBO3177 by TMHMM2.0 at aa 12-34, 47-69, 76-93, 103-125 and 132-154 413999014195 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 413999014196 Pfam match to entry PF01613 Flavin_Reduct, Flavin reductase like domain, score -5.6, E-value 4e-05 413999014197 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 413999014198 Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376 413999014199 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 413999014200 1 probable transmembrane helix predicted for CBO3179 by TMHMM2.0 at aa 7-24 413999014201 Pfam match to entry PF03734 ErfK_YbiS_YhnG,ErfK/YbiS/YcfS/YnhG, score 123.7, E-value 3.7e-34 413999014202 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain, score 24.0, E-value 3e-06 413999014203 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 413999014204 8 probable transmembrane helices predicted for CBO3180 by TMHMM2.0 at aa 4-21, 34-56, 102-124, 131-153,168-190, 195-217, 237-254 and 261-278 413999014205 Protein of unknown function (DUF1255); Region: DUF1255; pfam06865 413999014206 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232 413999014207 pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880 413999014208 Pfam match to entry PF01089 P5CR, Delta 1-pyrroline-5-carboxylate reductase, score 365.6, E-value 5.3e-107 413999014209 PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 413999014210 glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774 413999014211 Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677 413999014212 dimer interface [polypeptide binding]; other site 413999014213 active site 413999014214 glycine loop; other site 413999014215 Pfam match to entry PF01228 Gly_radical, Glycine radical, score 68.2, E-value 1.8e-17 413999014216 Pfam match to entry PF02901 PFL, Pyruvate formate lyase, score 277.3, E-value 2.1e-80 413999014217 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999014218 4Fe-4S dicluster domain; Region: Fer4_9; pfam13187 413999014219 pyruvate formate lyase II activase; Provisional; Region: PRK10076 413999014220 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 61.8, E-value 1.6e-15 413999014221 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 34.9, E-value 1.9e-07 413999014222 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999014223 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 21.0, E-value 0.00012 413999014224 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999014225 sequence-specific DNA binding site [nucleotide binding]; other site 413999014226 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 413999014227 salt bridge; other site 413999014228 Cupin domain; Region: Cupin_2; pfam07883 413999014229 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 54.2, E-value 3.1e-13 413999014230 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 413999014231 Dimer interface [polypeptide binding]; other site 413999014232 BRCT sequence motif; other site 413999014233 Pfam match to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) domain, score 23.2, E-value 1.6e-06 413999014234 agmatine deiminase; Region: agmatine_aguA; TIGR03380 413999014235 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2425 413999014236 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057 413999014237 metal ion-dependent adhesion site (MIDAS); other site 413999014238 Pfam match to entry PF00092 vwa, von Willebrand factor type A domain, score 24.0, E-value 7.5e-05 413999014239 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999014240 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 413999014241 Walker A motif; other site 413999014242 ATP binding site [chemical binding]; other site 413999014243 Walker B motif; other site 413999014244 arginine finger; other site 413999014245 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014246 Saccharopine dehydrogenase N-terminal domain; Region: SDH_N_domain; cl04528 413999014247 Uncharacterized conserved protein [Function unknown]; Region: COG1915 413999014248 Uncharacterized conserved protein [Function unknown]; Region: COG1915 413999014249 4Fe-4S single cluster domain; Region: Fer4_15; pfam13459 413999014250 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 10.7, E-value 0.0053 413999014251 CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; pfam09989 413999014252 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581 413999014253 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581 413999014254 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924 413999014255 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999014256 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 124.6, E-value 1.9e-34 413999014257 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221 413999014258 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999014259 Walker A motif; other site 413999014260 ATP binding site [chemical binding]; other site 413999014261 Walker B motif; other site 413999014262 arginine finger; other site 413999014263 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 413999014264 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family, score 52.2, E-value 1.2e-12 413999014265 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999014266 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 446.0, E-value 3.3e-131 413999014267 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999014268 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999014269 butyric acid fermentation 413999014270 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 413999014271 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 413999014272 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 413999014273 PS00696 Electron transfer flavoprotein alpha-subunit signature. 413999014274 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit, score 523.2, E-value 1.9e-154 413999014275 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 413999014276 Ligand binding site [chemical binding]; other site 413999014277 Electron transfer flavoprotein domain; Region: ETF; pfam01012 413999014278 Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit, score 400.8, E-value 1.4e-117 413999014279 PS01065 Electron transfer flavoprotein beta-subunit signature. 413999014280 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 413999014281 Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158 413999014282 FAD binding site [chemical binding]; other site 413999014283 homotetramer interface [polypeptide binding]; other site 413999014284 substrate binding pocket [chemical binding]; other site 413999014285 catalytic base [active] 413999014286 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain, score 271.7, E-value 1e-78 413999014287 PS00073 Acyl-CoA dehydrogenases signature 2. 413999014288 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain, score 183.0, E-value 5.2e-52 413999014289 PS00072 Acyl-CoA dehydrogenases signature 1. 413999014290 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain, score 172.2, E-value 9e-49 413999014291 putative acyltransferase; Provisional; Region: PRK05790 413999014292 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 413999014293 dimer interface [polypeptide binding]; other site 413999014294 active site 413999014295 Pfam match to entry PF02803 thiolase_C, Thiolase,C-terminal domain, score 273.1, E-value 3.9e-79 413999014296 PS00099 Thiolases active site. 413999014297 PS00737 Thiolases signature 2. 413999014298 Pfam match to entry PF00108 thiolase, Thiolase,N-terminal domain, score 580.7, E-value 9.9e-172 413999014299 PS00098 Thiolases acyl-enzyme intermediate signature. 413999014300 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808 413999014301 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 413999014302 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 413999014303 Pfam match to entry PF00725 3HCDH,3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, score 183.8, E-value 2.9e-52 413999014304 PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 413999014305 Pfam match to entry PF02737 3HCDH_N,3-hydroxyacyl-CoA dehydrogenase, NAD binding domain, score 285.6, E-value 6.8e-83 413999014306 3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809 413999014307 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 413999014308 substrate binding site [chemical binding]; other site 413999014309 oxyanion hole (OAH) forming residues; other site 413999014310 trimer interface [polypeptide binding]; other site 413999014311 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase, score 251.0, E-value 1.8e-72 413999014312 PS00166 Enoyl-CoA hydratase/isomerase signature. 413999014313 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 413999014314 GIY-YIG motif/motif A; other site 413999014315 active site 413999014316 catalytic site [active] 413999014317 putative DNA binding site [nucleotide binding]; other site 413999014318 metal binding site [ion binding]; metal-binding site 413999014319 Pfam match to entry PF01541 Exci_endo_N,Endo/excinuclease amino terminal domain, score 75.0,E-value 1.6e-19 413999014320 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 413999014321 9 probable transmembrane helices predicted for CBO3205 by TMHMM2.0 at aa 20-42, 49-71, 97-119, 136-158,168-190, 197-214, 245-267, 323-345 and 383-405 413999014322 Pfam match to entry PF00860 xan_ur_permease,Permease, score 85.4, E-value 1.2e-22 413999014323 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999014324 Zn2+ binding site [ion binding]; other site 413999014325 Mg2+ binding site [ion binding]; other site 413999014326 Pfam match to entry PF01966 HD, HD domain, score 67.4, E-value 3.2e-17 413999014327 prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437 413999014328 Pfam match to entry PF01790 LGT, Prolipoprotein diacylglyceryl transferase, score 388.0, E-value 9.5e-114 413999014329 7 probable transmembrane helices predicted for CBO3209 by TMHMM2.0 at aa 11-33, 45-67, 87-104, 111-128,170-189, 196-213 and 226-248 413999014330 PS01311 Prolipoprotein diacylglyceryl transferase signature. 413999014331 Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841 413999014332 homotetramer interface [polypeptide binding]; other site 413999014333 active site 413999014334 metal binding site [ion binding]; metal-binding site 413999014335 Pfam match to entry PF00149 Metallophos,Calcineurin-like phosphoesterase, score 31.3, E-value 2.3e-06 413999014336 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 413999014337 Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563 413999014338 active site 413999014339 catalytic site [active] 413999014340 metal binding site [ion binding]; metal-binding site 413999014341 dimer interface [polypeptide binding]; other site 413999014342 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase, score 182.7, E-value 6.3e-52 413999014343 Cache domain; Region: Cache_1; pfam02743 413999014344 HAMP domain; Region: HAMP; pfam00672 413999014345 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999014346 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999014347 dimer interface [polypeptide binding]; other site 413999014348 putative CheW interface [polypeptide binding]; other site 413999014349 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 136.7, E-value 4.3e-38 413999014350 Pfam match to entry PF00672 HAMP, HAMP domain,score 33.8, E-value 4e-07 413999014351 2 probable transmembrane helices predicted for CBO3213 by TMHMM2.0 at aa 10-32 and 283-305 413999014352 Pfam match to entry PF02743 Cache, Cache domain,score 68.6, E-value 1.4e-17 413999014353 Rubredoxin [Energy production and conversion]; Region: COG1773 413999014354 Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729 413999014355 iron binding site [ion binding]; other site 413999014356 Rubrerythrin [Energy production and conversion]; Region: COG1592 413999014357 rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046 413999014358 diiron binding motif [ion binding]; other site 413999014359 Pfam match to entry PF02915 Rubrerythrin,Rubrerythrin, score 96.1, E-value 7.5e-26 413999014360 Pfam match to entry PF00301 rubredoxin, Rubredoxin,score 44.7, E-value 2.2e-10 413999014361 pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493 413999014362 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999014363 FeS/SAM binding site; other site 413999014364 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 88.1, E-value 1.8e-23 413999014365 PS01087 Radical activating enzymes signature. 413999014366 PS00190 Cytochrome c family heme-binding site signature. 413999014367 formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255 413999014368 Pyruvate formate lyase 1; Region: PFL1; cd01678 413999014369 coenzyme A binding site [chemical binding]; other site 413999014370 active site 413999014371 catalytic residues [active] 413999014372 glycine loop; other site 413999014373 Pfam match to entry PF01228 Gly_radical, Glycine radical, score 182.1, E-value 9.3e-52 413999014374 PS00850 Glycine radical signature. 413999014375 Pfam match to entry PF02901 PFL, Pyruvate formate lyase, score 1095.6, E-value 0 413999014376 50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618 413999014377 Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495 413999014378 5S rRNA interface [nucleotide binding]; other site 413999014379 CTC domain interface [polypeptide binding]; other site 413999014380 L16 interface [polypeptide binding]; other site 413999014381 Pfam match to entry PF01386 Ribosomal_L25p,Ribosomal L25p family, score 32.5, E-value 1.1e-06 413999014382 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999014383 1 probable transmembrane helix predicted for CBO3219 by TMHMM2.0 at aa 4-26 413999014384 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 413999014385 metal binding site 2 [ion binding]; metal-binding site 413999014386 putative DNA binding helix; other site 413999014387 metal binding site 1 [ion binding]; metal-binding site 413999014388 dimer interface [polypeptide binding]; other site 413999014389 structural Zn2+ binding site [ion binding]; other site 413999014390 Pfam match to entry PF01475 FUR, Ferric uptake regulator family, score 125.0, E-value 1.4e-34 413999014391 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 413999014392 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 413999014393 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein, score 41.1, E-value 2.7e-09 413999014394 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999014395 1 probable transmembrane helix predicted for CBO3222 by TMHMM2.0 at aa 13-30 413999014396 HTH domain; Region: HTH_11; pfam08279 413999014397 WYL domain; Region: WYL; pfam13280 413999014398 1 probable transmembrane helix predicted for CBO3225 by TMHMM2.0 at aa 35-57 413999014399 CAAX protease self-immunity; Region: Abi; pfam02517 413999014400 6 probable transmembrane helices predicted for CBO3226 by TMHMM2.0 at aa 6-24, 31-53, 98-120, 141-163,178-196 and 217-239 413999014401 Pfam match to entry PF02517 Abi, CAAX amino terminal protease, score 41.9, E-value 1.5e-09 413999014402 YihA (EngB) GTPase family; Region: YihA_EngB; cd01876 413999014403 G1 box; other site 413999014404 GTP/Mg2+ binding site [chemical binding]; other site 413999014405 Switch I region; other site 413999014406 G2 box; other site 413999014407 G3 box; other site 413999014408 Switch II region; other site 413999014409 G4 box; other site 413999014410 G5 box; other site 413999014411 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014412 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466 413999014413 Found in ATP-dependent protease La (LON); Region: LON; smart00464 413999014414 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999014415 Walker A motif; other site 413999014416 ATP binding site [chemical binding]; other site 413999014417 Walker B motif; other site 413999014418 arginine finger; other site 413999014419 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 413999014420 Pfam match to entry PF05362 Lon_C, Lon protease (S16) C-terminal proteolytic domain, score 487.5, E-value 1.1e-143 413999014421 PS01046 ATP-dependent serine proteases, lon family,serine active site. 413999014422 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 165.1, E-value 1.2e-46 413999014423 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014424 Pfam match to entry PF02190 LON, ATP-dependent protease La (LON) domain, score 102.6, E-value 8.3e-28 413999014425 ATP-dependent protease LonB; Region: spore_lonB; TIGR02902 413999014426 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999014427 Walker A motif; other site 413999014428 ATP binding site [chemical binding]; other site 413999014429 Walker B motif; other site 413999014430 arginine finger; other site 413999014431 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 413999014432 Pfam match to entry PF05362 Lon_C, Lon protease (S16) C-terminal proteolytic domain, score 26.4, E-value 8.2e-17 413999014433 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 82.5, E-value 9.4e-22 413999014434 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999014435 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014436 1 probable transmembrane helix predicted for CBO3229 by TMHMM2.0 at aa 5-24 413999014437 ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342 413999014438 ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689 413999014439 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999014440 Walker A motif; other site 413999014441 ATP binding site [chemical binding]; other site 413999014442 Walker B motif; other site 413999014443 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 413999014444 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 104.8, E-value 1.7e-28 413999014445 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014446 Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740 413999014447 Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017 413999014448 oligomer interface [polypeptide binding]; other site 413999014449 active site residues [active] 413999014450 Pfam match to entry PF00574 CLP_protease, Clp protease, score 469.2, E-value 3.7e-138 413999014451 PS00382 Endopeptidase Clp histidine active site. 413999014452 PS00381 Endopeptidase Clp serine active site. 413999014453 trigger factor; Provisional; Region: tig; PRK01490 413999014454 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 413999014455 Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698 413999014456 Pfam match to entry PF05698 Trigger_C, Bacterial trigger factor protein (TF) C-terminus, score 210.5,E-value 2.7e-60 413999014457 Pfam match to entry PF00254 FKBP, FKBP-type peptidyl-prolyl cis-trans isomerase, score 75.7, E-value 1e-19 413999014458 Pfam match to entry PF05697 Trigger_N, Bacterial trigger factor protein (TF), score 232.5, E-value 6.4e-67 413999014459 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 413999014460 AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060 413999014461 DNA interaction; other site 413999014462 Metal-binding active site; metal-binding site 413999014463 Pfam match to entry PF01261 AP_endonuc_2, AP endonuclease 2, score 79.4, E-value 7.7e-21 413999014464 1 probable transmembrane helix predicted for CBO3234 by TMHMM2.0 at aa 21-43 413999014465 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999014466 active site 413999014467 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 74.8, E-value 1.9e-19 413999014468 dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037 413999014469 Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740 413999014470 heterodimer interface [polypeptide binding]; other site 413999014471 active site 413999014472 FMN binding site [chemical binding]; other site 413999014473 homodimer interface [polypeptide binding]; other site 413999014474 substrate binding site [chemical binding]; other site 413999014475 Pfam match to entry PF01180 DHOdehase,Dihydroorotate dehydrogenase, score 292.0, E-value 7.8e-85 413999014476 PS00912 Dihydroorotate dehydrogenase signature 2. 413999014477 dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054 413999014478 FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218 413999014479 FAD binding pocket [chemical binding]; other site 413999014480 FAD binding motif [chemical binding]; other site 413999014481 phosphate binding motif [ion binding]; other site 413999014482 beta-alpha-beta structure motif; other site 413999014483 NAD binding pocket [chemical binding]; other site 413999014484 Iron coordination center [ion binding]; other site 413999014485 Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725 413999014486 active site 413999014487 dimer interface [polypeptide binding]; other site 413999014488 Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family, score 72.8,E-value 7.6e-19 413999014489 dihydroorotase; Validated; Region: pyrC; PRK09357 413999014490 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 413999014491 Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317 413999014492 active site 413999014493 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 78.8, E-value 1.1e-20 413999014494 PS00483 Dihydroorotase signature 2. 413999014495 PS00482 Dihydroorotase signature 1. 413999014496 aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893 413999014497 Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948 413999014498 Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748 413999014499 Pfam match to entry PF01948 PyrI, Aspartate carbamoyltransferase regulatory chain, allosteric domain,score 70.1, E-value 4.9e-18 413999014500 aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856 413999014501 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 413999014502 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 413999014503 Pfam match to entry PF00185 OTCace,Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain, score 151.5, E-value 1.6e-42 413999014504 Pfam match to entry PF02729 OTCace_N,Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain, score 212.6, E-value 6e-61 413999014505 PS00097 Aspartate and ornithine carbamoyltransferases signature. 413999014506 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 413999014507 nucleotide binding site [chemical binding]; other site 413999014508 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 207.6, E-value 1.9e-59 413999014509 Protein of unknown function (DUF3343); Region: DUF3343; pfam11823 413999014510 benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263 413999014511 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999014512 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 386.0, E-value 3.8e-113 413999014513 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999014514 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 316.4, E-value 3.6e-92 413999014515 DsrE/DsrF-like family; Region: DrsE; cl00672 413999014516 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 413999014517 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 413999014518 Walker A/P-loop; other site 413999014519 ATP binding site [chemical binding]; other site 413999014520 Q-loop/lid; other site 413999014521 ABC transporter signature motif; other site 413999014522 Walker B; other site 413999014523 D-loop; other site 413999014524 H-loop/switch region; other site 413999014525 Pfam match to entry PF00005 ABC_tran, ABC transporter score 190.5, E-value 2.9e-54 413999014526 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014527 1 probable transmembrane helix predicted for CBO3248 by TMHMM2.0 at aa 13-32 413999014528 Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport system inner membrane component, score 12.9, E-value 0.0011 413999014529 5 probable transmembrane helices predicted for CBO3249 by TMHMM2.0 at aa 28-46, 89-106, 119-138, 143-162 and 183-205 413999014530 1 probable transmembrane helix predicted for CBO3251 by TMHMM2.0 at aa 5-23 413999014531 Alkylmercury lyase; Region: MerB; pfam03243 413999014532 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 413999014533 NMT1-like family; Region: NMT1_2; pfam13379 413999014534 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999014535 1 probable transmembrane helix predicted for CBO3255 by TMHMM2.0 at aa 7-24 413999014536 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999014537 Predicted permeases [General function prediction only]; Region: COG0701 413999014538 9 probable transmembrane helices predicted for CBO3256 by TMHMM2.0 at aa 20-39, 60-82, 86-108, 115-134,182-204, 213-235, 239-261, 282-304 and 326-347 413999014539 Pfam match to entry PF03773 DUF318, Predicted permease, score 140.8, E-value 2.5e-39 413999014540 Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841 413999014541 homotetramer interface [polypeptide binding]; other site 413999014542 active site 413999014543 metal binding site [ion binding]; metal-binding site 413999014544 Pfam match to entry PF00149 Metallophos,Calcineurin-like phosphoesterase, score 30.1, E-value 9.5e-08 413999014545 NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515 413999014546 active site 413999014547 dimerization interface [polypeptide binding]; other site 413999014548 Pfam match to entry PF01725 Ham1p_like, Ham1 family, score 246.6, E-value 3.6e-71 413999014549 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 413999014550 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 413999014551 peptide binding site [polypeptide binding]; other site 413999014552 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, score 71.8, E-value 1.5e-18 413999014553 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999014554 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999014555 aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477 413999014556 GatB/GatE catalytic domain; Region: GatB_N; pfam02934 413999014557 GatB domain; Region: GatB_Yqey; smart00845 413999014558 Pfam match to entry PF02637 GatB_Yqey, GatB/Yqey domain, score 199.7, E-value 4.7e-57 413999014559 Pfam match to entry PF01162 GatB, PET112 family, C terminal region, score 132.8, E-value 6.7e-37 413999014560 Pfam match to entry PF02934 GatB_N, PET112 family,N terminal region, score 505.9, E-value 3.3e-149 413999014561 PS01234 PET112 family signature. 413999014562 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154 413999014563 aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012 413999014564 Pfam match to entry PF01425 Amidase, Amidase, score 700.3, E-value 9.5e-208 413999014565 PS00571 Amidases signature. 413999014566 aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034 413999014567 Pfam match to entry PF02686 Glu-tRNAGln,Glu-tRNAGln amidotransferase C subunit, score 65.8,E-value 9.5e-17 413999014568 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 413999014569 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 413999014570 Pfam match to entry PF00375 SDF,Sodium:dicarboxylate symporter family, score -42.2,E-value 4.1e-08 413999014571 8 probable transmembrane helices predicted for CBO3268 by TMHMM2.0 at aa 5-23, 38-60, 73-95, 123-145,166-188, 203-225, 273-295 and 310-332 413999014572 3 probable transmembrane helices predicted for CBO3269 by TMHMM2.0 at aa 12-34, 44-60 and 73-91 413999014573 NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956 413999014574 NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114 413999014575 nucleotide binding pocket [chemical binding]; other site 413999014576 K-X-D-G motif; other site 413999014577 catalytic site [active] 413999014578 NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120 413999014579 NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119 413999014580 H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815 413999014581 DNA binding site [nucleotide binding] 413999014582 metal binding site [ion binding]; metal-binding site 413999014583 Helix-hairpin-helix motif; Region: HHH; pfam00633 413999014584 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 413999014585 Dimer interface [polypeptide binding]; other site 413999014586 Pfam match to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) domain, score 59.0, E-value 1.1e-14 413999014587 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 33.0, E-value 7e-07 413999014588 Pfam match to entry PF03119 DNA_ligase_ZBD,NAD-dependent DNA ligase C4 zinc finger domain, score 25.6, E-value 0.00012 413999014589 Pfam match to entry PF03120 DNA_ligase_OB,NAD-dependent DNA ligase OB-fold domain, score 130.4,E-value 3.5e-36 413999014590 PS01056 NAD-dependent DNA ligase signature 2. 413999014591 Pfam match to entry PF01653 DNA_ligase_N,NAD-dependent DNA ligase adenylation domain, score 333.3,E-value 2.9e-97 413999014592 ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073 413999014593 Part of AAA domain; Region: AAA_19; pfam13245 413999014594 Family description; Region: UvrD_C_2; pfam13538 413999014595 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 715.6, E-value 2.4e-212 413999014596 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014597 Trp repressor protein; Region: Trp_repressor; cl17266 413999014598 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 413999014599 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999014600 RNA binding surface [nucleotide binding]; other site 413999014601 Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553 413999014602 active site 413999014603 uracil binding [chemical binding]; other site 413999014604 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase, score 61.1, E-value 2.4e-15 413999014605 PS01149 Rsu family of pseudouridine synthase signature. 413999014606 Pfam match to entry PF01479 S4, S4 domain, score 45.9, E-value 9.2e-11 413999014607 lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222 413999014608 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 413999014609 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 413999014610 N-acetyl-D-glucosamine binding site [chemical binding]; other site 413999014611 catalytic residue [active] 413999014612 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain, score 121.3, E-value 1.9e-33 413999014613 PS00922 Prokaryotic transglycosylases signature. 413999014614 triple tyrosine motif-containing protein; Provisional; Region: PRK14081 413999014615 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999014616 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999014617 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999014618 Y_Y_Y domain; Region: Y_Y_Y; pfam07495 413999014619 hypothetical protein; Validated; Region: PRK00124 413999014620 Pfam match to entry PF02639 DUF188, Uncharacterized BCR, YaiI/YqxD family COG1671, score 77.0, E-value 4e-20 413999014621 glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097 413999014622 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015 413999014623 active site 413999014624 dimer interface [polypeptide binding]; other site 413999014625 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016 413999014626 dimer interface [polypeptide binding]; other site 413999014627 active site 413999014628 Pfam match to entry PF00342 PGI, Phosphoglucose isomerase, score 494.7, E-value 7.2e-146 413999014629 PS00174 Phosphoglucose isomerase signature 2. 413999014630 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014631 PS00765 Phosphoglucose isomerase signature 1. 413999014632 Probable zinc-binding domain; Region: zf-trcl; pfam13451 413999014633 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999014634 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999014635 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 69.2, E-value 9.4e-18 413999014636 PS01081 Bacterial regulatory proteins, tetR family signature. 413999014637 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 28.4, E-value 4.9e-09 413999014638 D-lactate dehydrogenase; Validated; Region: PRK08605 413999014639 D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186 413999014640 homodimer interface [polypeptide binding]; other site 413999014641 ligand binding site [chemical binding]; other site 413999014642 NAD binding site [chemical binding]; other site 413999014643 catalytic site [active] 413999014644 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain,score 67.1, E-value 3.9e-17 413999014645 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain,score 245.6, E-value 7.1e-71 413999014646 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 413999014647 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 413999014648 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 413999014649 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 413999014650 Putative Lactate dehydrogenase and (R)-2-Hydroxyglutarate Dehydrogenase-like proteins, NAD-binding and catalytic domains; Region: HGDH_LDH_like; cd12185 413999014651 putative ligand binding site [chemical binding]; other site 413999014652 putative NAD binding site [chemical binding]; other site 413999014653 catalytic site [active] 413999014654 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain,score 273.7, E-value 2.5e-79 413999014655 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 413999014656 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 413999014657 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 413999014658 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain,score 88.7, E-value 1.3e-23 413999014659 Uncharacterized membrane protein [Function unknown]; Region: COG3949 413999014660 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 413999014661 10 probable transmembrane helices predicted for CBO3285 by TMHMM2.0 at aa 20-39, 54-76, 103-125, 130-152,159-181, 204-226, 239-261, 281-303, 324-346 and 352-370 413999014662 4Fe-4S binding domain; Region: Fer4; pfam00037 413999014663 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 413999014664 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 413999014665 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 413999014666 PS00696 Electron transfer flavoprotein alpha-subunit signature. 413999014667 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit, score 464.7, E-value 8.2e-137 413999014668 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 31.3, E-value 2.4e-06 413999014669 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999014670 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 35.5, E-value 1.3e-07 413999014671 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999014672 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 413999014673 Ligand binding site [chemical binding]; other site 413999014674 Electron transfer flavoprotein domain; Region: ETF; pfam01012 413999014675 Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit, score 343.6, E-value 2.3e-100 413999014676 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 413999014677 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 413999014678 active site 413999014679 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain, score 277.2, E-value 2.2e-80 413999014680 PS00073 Acyl-CoA dehydrogenases signature 2. 413999014681 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain, score 151.3, E-value 1.8e-42 413999014682 PS00072 Acyl-CoA dehydrogenases signature 1. 413999014683 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain, score 153.5, E-value 3.8e-43 413999014684 benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263 413999014685 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999014686 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 566.3, E-value 2e-167 413999014687 benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260 413999014688 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999014689 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 710.2, E-value 9.7e-211 413999014690 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924 413999014691 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 413999014692 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 260.7, E-value 2e-75 413999014693 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 413999014694 CoA-transferase family III; Region: CoA_transf_3; pfam02515 413999014695 Pfam match to entry PF02515 CoA_transf_3,CoA-transferase III, score 90.7, E-value 3e-24 413999014696 AMP-binding domain protein; Validated; Region: PRK08315 413999014697 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 413999014698 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917 413999014699 acyl-activating enzyme (AAE) consensus motif; other site 413999014700 putative AMP binding site [chemical binding]; other site 413999014701 putative active site [active] 413999014702 putative CoA binding site [chemical binding]; other site 413999014703 Pfam match to entry PF00501 AMP-binding,AMP-binding enzyme, score 354.3, E-value 1.4e-103 413999014704 PS00455 AMP-binding domain signature. 413999014705 Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547 413999014706 Pfam match to entry PF05525 Branch_AA_trans,Branched-chain amino acid transport protein, score 479.7,E-value 2.5e-141 413999014707 12 probable transmembrane helices predicted for CBO3294 by TMHMM2.0 at aa 12-29, 42-64, 77-99, 114-136,152-174, 194-213, 226-248, 273-295, 308-330, 334-356,368-390 and 405-424 413999014708 GMP synthase; Reviewed; Region: guaA; PRK00074 413999014709 Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742 413999014710 AMP/PPi binding site [chemical binding]; other site 413999014711 candidate oxyanion hole; other site 413999014712 catalytic triad [active] 413999014713 potential glutamine specificity residues [chemical binding]; other site 413999014714 The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997 413999014715 ATP Binding subdomain [chemical binding]; other site 413999014716 Ligand Binding sites [chemical binding]; other site 413999014717 Dimerization subdomain; other site 413999014718 Pfam match to entry PF00958 GMP_synt_C, GMP synthase C terminal domain, score 250.6, E-value 2.3e-72 413999014719 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I, score 180.7, E-value 2.6e-51 413999014720 PS00442 Glutamine amidotransferases class-I active site. 413999014721 inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567 413999014722 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 413999014723 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601 413999014724 IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381 413999014725 active site 413999014726 Pfam match to entry PF00478 IMPDH, IMP dehydrogenase / GMP reductase domain, score 713.8, E-value 8.2e-212 413999014727 PS00487 IMP dehydrogenase / GMP reductase signature. 413999014728 Pfam match to entry PF00571 CBS, CBS domain, score 52.6, E-value 9.2e-13 413999014729 Pfam match to entry PF00571 CBS, CBS domain, score 57.0, E-value 4.4e-14 413999014730 tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696 413999014731 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_II; cd01993 413999014732 Ligand Binding Site [chemical binding]; other site 413999014733 Pfam match to entry PF01171 ATP_bind3, PP-loop family, score 63.1, E-value 6.1e-16 413999014734 chaperonin GroEL; Reviewed; Region: groEL; PRK12849 413999014735 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 413999014736 ring oligomerisation interface [polypeptide binding]; other site 413999014737 ATP/Mg binding site [chemical binding]; other site 413999014738 stacking interactions; other site 413999014739 hinge regions; other site 413999014740 Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family, score 656.1, E-value 1.9e-194 413999014741 PS00296 Chaperonins cpn60 signature. 413999014742 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 413999014743 oligomerisation interface [polypeptide binding]; other site 413999014744 mobile loop; other site 413999014745 roof hairpin; other site 413999014746 Pfam match to entry PF00166 cpn10, Chaperonin 10 Kd subunit, score 193.5, E-value 3.6e-55 413999014747 PS00681 Chaperonins cpn10 signature. 413999014748 Protein of unknown function (DUF1461); Region: DUF1461; pfam07314 413999014749 4 probable transmembrane helices predicted for CBO3300 by TMHMM2.0 at aa 12-31, 98-120, 127-149 and 185-207 413999014750 Uncharacterized conserved protein [Function unknown]; Region: COG0398 413999014751 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 413999014752 6 probable transmembrane helices predicted for CBO3301 by TMHMM2.0 at aa 25-44, 59-81, 102-124, 144-161,182-201 and 211-230 413999014753 [FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105 413999014754 4Fe-4S binding domain; Region: Fer4; pfam00037 413999014755 4Fe-4S binding domain; Region: Fer4; pfam00037 413999014756 Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906 413999014757 Pfam match to entry PF02906 Fe_hyd_lg_C, Iron only hydrogenase large subunit, C-terminal domain, score 0.7,E-value 4.5e-17 413999014758 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 37.3, E-value 3.6e-08 413999014759 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999014760 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 35.8, E-value 1e-07 413999014761 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999014762 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122 413999014763 8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934 413999014764 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 413999014765 minor groove reading motif; other site 413999014766 helix-hairpin-helix signature motif; other site 413999014767 substrate binding pocket [chemical binding]; other site 413999014768 active site 413999014769 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein, score 53.3,E-value 5.6e-13 413999014770 putative oxidoreductase; Provisional; Region: PRK12831 413999014771 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999014772 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999014773 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 104.6, E-value 2e-28 413999014774 ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222 413999014775 FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219 413999014776 FAD binding pocket [chemical binding]; other site 413999014777 FAD binding motif [chemical binding]; other site 413999014778 phosphate binding motif [ion binding]; other site 413999014779 beta-alpha-beta structure motif; other site 413999014780 NAD binding pocket [chemical binding]; other site 413999014781 Iron coordination center [ion binding]; other site 413999014782 Pfam match to entry PF00175 NAD_binding_1,Oxidoreductase NAD-binding domain, score 3.0, E-value 0.00011 413999014783 redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472 413999014784 Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971 413999014785 CoA binding domain; Region: CoA_binding; pfam02629 413999014786 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 413999014787 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999014788 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999014789 ABC transporter; Region: ABC_tran_2; pfam12848 413999014790 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 413999014791 Pfam match to entry PF00005 ABC_tran, ABC transporter score 141.7, E-value 1.4e-39 413999014792 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014793 PS00211 ABC transporters family signature. 413999014794 Pfam match to entry PF00005 ABC_tran, ABC transporter score 112.1, E-value 1.1e-30 413999014795 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014796 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 413999014797 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999014798 active site 413999014799 phosphorylation site [posttranslational modification] 413999014800 intermolecular recognition site; other site 413999014801 dimerization interface [polypeptide binding]; other site 413999014802 LytTr DNA-binding domain; Region: LytTR; pfam04397 413999014803 Pfam match to entry PF04397 LytTR, LytTr DNA-binding domain, score 110.4, E-value 3.5e-30 413999014804 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 86.8, E-value 4.7e-23 413999014805 Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275 413999014806 5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694 413999014807 Histidine kinase; Region: His_kinase; pfam06580 413999014808 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999014809 ATP binding site [chemical binding]; other site 413999014810 Mg2+ binding site [ion binding]; other site 413999014811 G-X-G motif; other site 413999014812 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 53.1,E-value 6.4e-13 413999014813 5 probable transmembrane helices predicted for CBO3309 by TMHMM2.0 at aa 38-60, 70-92, 99-121, 136-153 and 166-188 413999014814 Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966 413999014815 Carbon starvation protein CstA; Region: CstA; pfam02554 413999014816 Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966 413999014817 C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722 413999014818 Pfam match to entry PF02554 CstA, Carbon starvation protein CstA, score 167.3, E-value 2.7e-47 413999014819 13 probable transmembrane helices predicted for CBO3310 by TMHMM2.0 at aa 4-22, 53-75, 79-101, 127-149,159-181, 188-210, 225-242, 263-285, 316-338, 359-381,385-404, 409-431 and 441-458 413999014820 Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]; Region: COG1026 413999014821 Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675 413999014822 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 413999014823 Peptidase M16C associated; Region: M16C_assoc; pfam08367 413999014824 Pfam match to entry PF05193 Peptidase_M16_C,Peptidase M16 inactive domain, score 22.3, E-value 0.00053 413999014825 Pfam match to entry PF05193 Peptidase_M16_C,Peptidase M16 inactive domain, score 101.0, E-value 2.5e-27 413999014826 pyruvate carboxylase; Reviewed; Region: PRK12999 413999014827 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 413999014828 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 413999014829 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 413999014830 Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937 413999014831 active site 413999014832 catalytic residues [active] 413999014833 metal binding site [ion binding]; metal-binding site 413999014834 homodimer binding site [polypeptide binding]; other site 413999014835 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 413999014836 carboxyltransferase (CT) interaction site; other site 413999014837 biotinylation site [posttranslational modification]; other site 413999014838 Pfam match to entry PF00364 biotin_lipoyl,Biotin-requiring enzyme, score 89.4, E-value 7.6e-24 413999014839 PS00188 Biotin-requiring enzymes attachment site. 413999014840 Pfam match to entry PF02436 PYC_OADA, carboxylase domain, score 317.6, E-value 1.6e-92 413999014841 Pfam match to entry PF00682 HMGL-like, HMGL-like,score 147.4, E-value 2.7e-41 413999014842 Pfam match to entry PF02785 Biotin_carb_C, Biotin carboxylase C-terminal domain, score 196.4, E-value 4.8e-56 413999014843 Pfam match to entry PF02786 CPSase_L_D2,Carbamoyl-phosphate synthase L chain, ATP binding domain,score 360.9, E-value 1.4e-105 413999014844 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 413999014845 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 413999014846 Pfam match to entry PF00289 CPSase_L_chain,Carbamoyl-phosphate synthase L chain, N-terminal domain,score 155.1, E-value 1.3e-43 413999014847 UGMP family protein; Validated; Region: PRK09604 413999014848 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 413999014849 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 413999014850 Pfam match to entry PF00814 Peptidase_M22,Glycoprotease, score 390.7, E-value 1.5e-114 413999014851 Endodeoxyribonuclease RusA; Region: RusA; pfam05866 413999014852 Pfam match to entry PF05866 RusA,Endodeoxyribonuclease RusA, score 132.6, E-value 7.6e-37 413999014853 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999014854 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 413999014855 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 74.4, E-value 2.4e-19 413999014856 zinc-ribbon domain; Region: zf-ribbon_3; pfam13248 413999014857 5 probable transmembrane helices predicted for CBO3317 by TMHMM2.0 at aa 4-23, 132-151, 171-193, 198-220 and 248-270 413999014858 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 413999014859 Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297 413999014860 intersubunit interface [polypeptide binding]; other site 413999014861 Pfam match to entry PF01297 SBP_bac_9, Periplasmic solute binding protein family, score 49.0, E-value 1.4e-13 413999014862 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999014863 Zn2+ binding site [ion binding]; other site 413999014864 Mg2+ binding site [ion binding]; other site 413999014865 c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206 413999014866 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999014867 Zn2+ binding site [ion binding]; other site 413999014868 Mg2+ binding site [ion binding]; other site 413999014869 Pfam match to entry PF01966 HD, HD domain, score 33.5, E-value 5.2e-07 413999014870 Pfam match to entry PF01966 HD, HD domain, score 83.9, E-value 3.5e-22 413999014871 Predicted ATPase or kinase [General function prediction only]; Region: COG0802 413999014872 Pfam match to entry PF02367 UPF0079,Uncharacterised P-loop hydrolase UPF0079, score 158.6,E-value 1.1e-44 413999014873 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014874 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 413999014875 Glycoprotease family; Region: Peptidase_M22; pfam00814 413999014876 Pfam match to entry PF00814 Peptidase_M22,Glycoprotease, score 42.1, E-value 4.6e-12 413999014877 ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575 413999014878 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 413999014879 Coenzyme A binding pocket [chemical binding]; other site 413999014880 Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 85.9, E-value 8.6e-23 413999014881 tyrosyl-tRNA synthetase; Validated; Region: PRK05912 413999014882 catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805 413999014883 active site 413999014884 HIGH motif; other site 413999014885 dimer interface [polypeptide binding]; other site 413999014886 KMSKS motif; other site 413999014887 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999014888 RNA binding surface [nucleotide binding]; other site 413999014889 Pfam match to entry PF01479 S4, S4 domain, score 23.6, E-value 0.00049 413999014890 Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y), score 382.0, E-value 6.2e-112 413999014891 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 413999014892 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999014893 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865 413999014894 Divergent AAA domain; Region: AAA_4; pfam04326 413999014895 Pfam match to entry PF04326 AAA_div, Divergent AAA domain, score 50.0, E-value 5.5e-12 413999014896 ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155 413999014897 4 probable transmembrane helices predicted for CBO3326 by TMHMM2.0 at aa 12-34, 78-100, 113-135 and 160-177 413999014898 2 probable transmembrane helices predicted for CBO3327 by TMHMM2.0 at aa 10-29 and 69-86 413999014899 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 413999014900 PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386 413999014901 active site 413999014902 7 probable transmembrane helices predicted for CBO3328 by TMHMM2.0 at aa 26-45, 76-93, 143-165, 178-200,220-242, 251-273 and 278-300 413999014903 Pfam match to entry PF01569 PAP2, PAP2 superfamily,score 17.1, E-value 0.00014 413999014904 Peptide chain release factor RF-3 [Translation, ribosomal structure and biogenesis]; Region: PrfC; COG4108 413999014905 Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169 413999014906 G1 box; other site 413999014907 putative GEF interaction site [polypeptide binding]; other site 413999014908 GTP/Mg2+ binding site [chemical binding]; other site 413999014909 Switch I region; other site 413999014910 G2 box; other site 413999014911 G3 box; other site 413999014912 Switch II region; other site 413999014913 G4 box; other site 413999014914 G5 box; other site 413999014915 RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689 413999014916 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 40.9, E-value 3.1e-09 413999014917 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 234.0, E-value 2.2e-67 413999014918 PS00301 GTP-binding elongation factors signature. 413999014919 sugar phosphate phosphatase; Provisional; Region: PRK10513 413999014920 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999014921 active site 413999014922 motif I; other site 413999014923 motif II; other site 413999014924 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 413999014925 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 26.3, E-value 7.4e-05 413999014926 PS01228 Hypothetical cof family signature 1. 413999014927 tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282 413999014928 catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806 413999014929 active site 413999014930 HIGH motif; other site 413999014931 dimer interface [polypeptide binding]; other site 413999014932 KMSKS motif; other site 413999014933 Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y), score 343.9, E-value 1.9e-100 413999014934 PS00962 Ribosomal protein S2 signature 1. 413999014935 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 413999014936 desulfoferrodoxin; Region: dfx_rbo; TIGR00320 413999014937 Desulforedoxin (DSRD) domain; a small non-heme iron domain present in the desulforedoxin (rubredoxin oxidoreductase) and desulfoferrodoxin proteins of some archeael and bacterial methanogens and sulfate/sulfur reducers. Desulforedoxin is a small; Region: DSRD; cd00974 413999014938 non-heme iron binding site [ion binding]; other site 413999014939 dimer interface [polypeptide binding]; other site 413999014940 Superoxide reductase-like (SORL) domain, class I; SORL-domains are present in a family of mononuclear non-heme iron proteins that includes superoxide reductase and desulfoferrodoxin. Superoxide reductase-like proteins scavenge superoxide anion radicals...; Region: SORL_Dfx_classI; cd03171 413999014941 non-heme iron binding site [ion binding]; other site 413999014942 dimer interface [polypeptide binding]; other site 413999014943 Pfam match to entry PF01880 Desulfoferrodox,Desulfoferrodoxin, score 148.0, E-value 1.7e-41 413999014944 Protein of unknown function (DUF3131); Region: DUF3131; pfam11329 413999014945 Putative glucoamylase; Region: Glycoamylase; pfam10091 413999014946 Second GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_2_like; cd11753 413999014947 Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459 413999014948 First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756 413999014949 Pfam match to entry PF06205 GT36_AF,Glycosyltransferase 36 associated family, score 89.1,E-value 9.5e-24 413999014950 Pfam match to entry PF06165 Glyco_transf_36,Glycosyltransferase 36, score 105.7, E-value 9.3e-29 413999014951 Pfam match to entry PF06204 CBM_X, carbohydrate binding domain, score 108.4, E-value 1.5e-29 413999014952 Pfam match to entry PF06205 GT36_AF,Glycosyltransferase 36 associated family, score 69.4,E-value 8.1e-18 413999014953 Pfam match to entry PF06165 Glyco_transf_36,Glycosyltransferase 36, score 117.0, E-value 3.8e-32 413999014954 Pfam match to entry PF06204 CBM_X, carbohydrate binding domain, score 51.5, E-value 1.9e-12 413999014955 8 probable transmembrane helices predicted for CBO3335 by TMHMM2.0 at aa 4-23, 429-448, 458-480, 826-845,849-871, 892-914, 945-962 and 969-991 413999014956 PS00215 Mitochondrial energy transfer proteins signature. 413999014957 diaminopimelate decarboxylase; Region: lysA; TIGR01048 413999014958 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828 413999014959 active site 413999014960 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999014961 substrate binding site [chemical binding]; other site 413999014962 catalytic residues [active] 413999014963 dimer interface [polypeptide binding]; other site 413999014964 Pfam match to entry PF00278 Orn_DAP_Arg_deC,Pyridoxal-dependent decarboxylase, C-terminal sheet domain, score 147.2, E-value 3e-41 413999014965 Pfam match to entry PF02784 Orn_Arg_deC_N,Pyridoxal-dependent decarboxylase, pyridoxal binding domain, score 253.4, E-value 3.3e-73 413999014966 aspartate kinase; Reviewed; Region: PRK06635 413999014967 AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261 413999014968 putative nucleotide binding site [chemical binding]; other site 413999014969 putative catalytic residues [active] 413999014970 putative Mg ion binding site [ion binding]; other site 413999014971 putative aspartate binding site [chemical binding]; other site 413999014972 ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913 413999014973 putative allosteric regulatory site; other site 413999014974 ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936 413999014975 putative allosteric regulatory residue; other site 413999014976 Pfam match to entry PF01842 ACT, ACT domain, score 25.0, E-value 0.00018 413999014977 Pfam match to entry PF01842 ACT, ACT domain, score 13.3, E-value 0.14 413999014978 Pfam match to entry PF00696 aakinase, Amino acid kinase, score 233.1, E-value 4.1e-67 413999014979 PS00324 Aspartokinase signature. 413999014980 M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658 413999014981 Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127 413999014982 active site 413999014983 metal binding site [ion binding]; metal-binding site 413999014984 Pfam match to entry PF02127 Peptidase_M18,Aminopeptidase I zinc metalloprotease (M18), score 497.4,E-value 1.2e-146 413999014985 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 413999014986 cation diffusion facilitator family transporter; Region: CDF; TIGR01297 413999014987 4 probable transmembrane helices predicted for CBO3339 by TMHMM2.0 at aa 29-51, 98-116, 131-150 and 191-213 413999014988 Pfam match to entry PF01545 Cation_efflux, Cation efflux family, score 288.2, E-value 1.1e-83 413999014989 hypothetical protein; Provisional; Region: PRK06851 413999014990 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014991 Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973 413999014992 Part of AAA domain; Region: AAA_19; pfam13245 413999014993 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 2.7, E-value 0.66 413999014994 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 16.0, E-value 0.00015 413999014995 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase, score 4.6, E-value 0.21 413999014996 PS00017 ATP/GTP-binding site motif A (P-loop). 413999014997 FtsH Extracellular; Region: FtsH_ext; pfam06480 413999014998 ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241 413999014999 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999015000 Walker A motif; other site 413999015001 ATP binding site [chemical binding]; other site 413999015002 Walker B motif; other site 413999015003 arginine finger; other site 413999015004 Peptidase family M41; Region: Peptidase_M41; pfam01434 413999015005 Pfam match to entry PF01434 Peptidase_M41,Peptidase M41, score 344.2, E-value 1.5e-100 413999015006 PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. 413999015007 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 307.7, E-value 1.4e-89 413999015008 PS00674 AAA-protein family signature. 413999015009 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015010 2 probable transmembrane helices predicted for CBO3342 by TMHMM2.0 at aa 15-34 and 114-133 413999015011 dipeptidase PepV; Reviewed; Region: PRK07318 413999015012 M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888 413999015013 active site 413999015014 metal binding site [ion binding]; metal-binding site 413999015015 Pfam match to entry PF01546 Peptidase_M20,Peptidase M20/M25/M40, score 243.1, E-value 4e-70 413999015016 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015017 prolyl-tRNA synthetase; Provisional; Region: PRK08661 413999015018 Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778 413999015019 dimer interface [polypeptide binding]; other site 413999015020 motif 1; other site 413999015021 active site 413999015022 motif 2; other site 413999015023 motif 3; other site 413999015024 ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862 413999015025 anticodon binding site; other site 413999015026 zinc-binding site [ion binding]; other site 413999015027 Pfam match to entry PF03129 HGTP_anticodon,Anticodon binding domain, score 110.6, E-value 3.1e-30 413999015028 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score 109.4, E-value 7e-30 413999015029 The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456 413999015030 GIY-YIG motif/motif A; other site 413999015031 putative active site [active] 413999015032 putative metal binding site [ion binding]; other site 413999015033 Pfam match to entry PF01541 Exci_endo_N,Endo/excinuclease amino terminal domain, score 71.5,E-value 1.8e-18 413999015034 PS00294 Prenyl group binding site (CAAX box). 413999015035 putative transporter; Provisional; Region: PRK11660 413999015036 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 413999015037 Sulfate transporter family; Region: Sulfate_transp; pfam00916 413999015038 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 413999015039 PS00294 Prenyl group binding site (CAAX box). 413999015040 Pfam match to entry PF01740 STAS, STAS domain,score 36.7, E-value 5.6e-08 413999015041 Pfam match to entry PF00916 Sulfate_transp, Sulfate transporter family, score 310.6, E-value 1.9e-90 413999015042 11 probable transmembrane helices predicted for CBO3348 by TMHMM2.0 at aa 26-48, 68-90, 97-119, 123-145,170-192, 202-224, 254-276, 286-308, 321-340, 345-367 and 380-402 413999015043 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999015044 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 413999015045 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999015046 dimer interface [polypeptide binding]; other site 413999015047 phosphorylation site [posttranslational modification] 413999015048 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999015049 ATP binding site [chemical binding]; other site 413999015050 Mg2+ binding site [ion binding]; other site 413999015051 G-X-G motif; other site 413999015052 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 44.9,E-value 1.8e-10 413999015053 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 54.3, E-value 2.9e-13 413999015054 Pfam match to entry PF00672 HAMP, HAMP domain,score 29.7, E-value 7e-06 413999015055 2 probable transmembrane helices predicted for CBO3349 by TMHMM2.0 at aa 13-35 and 165-187 413999015056 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999015057 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999015058 active site 413999015059 phosphorylation site [posttranslational modification] 413999015060 intermolecular recognition site; other site 413999015061 dimerization interface [polypeptide binding]; other site 413999015062 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999015063 DNA binding site [nucleotide binding] 413999015064 ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866 413999015065 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 413999015066 6 probable transmembrane helices predicted for CBO3350 by TMHMM2.0 at aa 13-35, 153-175, 210-232,280-302, 309-331 and 375-397 413999015067 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999015068 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 413999015069 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999015070 Walker A/P-loop; other site 413999015071 ATP binding site [chemical binding]; other site 413999015072 Q-loop/lid; other site 413999015073 ABC transporter signature motif; other site 413999015074 Walker B; other site 413999015075 D-loop; other site 413999015076 H-loop/switch region; other site 413999015077 Pfam match to entry PF00005 ABC_tran, ABC transporter score 189.0, E-value 7.6e-54 413999015078 PS00211 ABC transporters family signature. 413999015079 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015080 2 probable transmembrane helices predicted for CBO3352 by TMHMM2.0 at aa 5-22 and 42-64 413999015081 PS00340 Growth factor and cytokines receptors family signature 2. 413999015082 Uncharacterized conserved protein [Function unknown]; Region: COG3589 413999015083 Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913 413999015084 Pfam match to entry PF05913 DUF871, Bacterial protein of unknown function (DUF871), score 560.1, E-value 1.6e-165 413999015085 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 413999015086 Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism]; Region: COG2971 413999015087 Pfam match to entry PF01869 BcrAD_BadFG,BadF/BadG/BcrA/BcrD ATPase, score 74.9, E-value 1.7e-19 413999015088 PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215 413999015089 methionine cluster; other site 413999015090 active site 413999015091 phosphorylation site [posttranslational modification] 413999015092 metal binding site [ion binding]; metal-binding site 413999015093 Pfam match to entry PF02255 PTS_IIA, PTS system,Lactose/Cellobiose specific IIA subunit, score 153.7,E-value 3.4e-43 413999015094 PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564 413999015095 active site 413999015096 P-loop; other site 413999015097 phosphorylation site [posttranslational modification] 413999015098 Pfam match to entry PF02302 PTS_IIB, PTS system,Lactose/Cellobiose specific IIB subunit, score 140.1,E-value 4.2e-39 413999015099 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221 413999015100 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999015101 Walker A motif; other site 413999015102 ATP binding site [chemical binding]; other site 413999015103 Walker B motif; other site 413999015104 arginine finger; other site 413999015105 Transcriptional antiterminator [Transcription]; Region: COG3933 413999015106 PRD domain; Region: PRD; pfam00874 413999015107 PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025 413999015108 active pocket/dimerization site; other site 413999015109 active site 413999015110 phosphorylation site [posttranslational modification] 413999015111 PRD domain; Region: PRD; pfam00874 413999015112 Pfam match to entry PF00874 PRD, PRD domain, score 35.3, E-value 1.5e-07 413999015113 Pfam match to entry PF03610 EIIA-man, PTS system fructose IIA component, score 46.2, E-value 7.9e-11 413999015114 Pfam match to entry PF00874 PRD, PRD domain, score 88.3, E-value 1.6e-23 413999015115 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 1.6, E-value 2.9e-12 413999015116 PS00690 DEAH-box subfamily ATP-dependent helicases signature. 413999015117 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999015118 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015119 cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592 413999015120 Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455 413999015121 9 probable transmembrane helices predicted for CBO3359 by TMHMM2.0 at aa 31-53, 74-96, 133-155, 176-198,218-240, 283-305, 325-347, 354-376 and 391-413 413999015122 Pfam match to entry PF02378 PTS_EIIC,Phosphotransferase system, EIIC, score 241.8, E-value 9.8e-70 413999015123 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486 413999015124 Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296 413999015125 NAD binding site [chemical binding]; other site 413999015126 sugar binding site [chemical binding]; other site 413999015127 divalent metal binding site [ion binding]; other site 413999015128 tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999015129 dimer interface [polypeptide binding]; other site 413999015130 Pfam match to entry PF02056 Glyco_hydro_4, Family 4 glycosyl hydrolase, score 614.2, E-value 8e-182 413999015131 PS01324 Glycosyl hydrolases family 4 signature. 413999015132 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 413999015133 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 413999015134 metal binding site [ion binding]; metal-binding site 413999015135 active site 413999015136 I-site; other site 413999015137 Pfam match to entry PF00990 GGDEF, GGDEF domain,score 154.8, E-value 1.6e-43 413999015138 2 probable transmembrane helices predicted for CBO3361 by TMHMM2.0 at aa 21-40 and 231-253 413999015139 Pfam match to entry PF02743 Cache, Cache domain,score 12.2, E-value 0.004 413999015140 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 413999015141 active site 413999015142 catalytic residues [active] 413999015143 DNA binding site [nucleotide binding] 413999015144 Int/Topo IB signature motif; other site 413999015145 Pfam match to entry PF00589 Phage_integrase, Phage integrase, score 73.8, E-value 3.7e-19 413999015146 S-adenosylmethionine decarboxylase proenzyme, Bacillus form; Region: SAM_DCase_Bsu; TIGR03330 413999015147 Pfam match to entry PF02675 AdoMetDC,S-adenosylmethionine decarboxylase, score 108.1, E-value 1.8e-29 413999015148 Protein of unknown function DUF43; Region: DUF43; pfam01861 413999015149 Pfam match to entry PF01861 DUF43, Protein of unknown function DUF43, score 35.4, E-value 6.1e-15 413999015150 Mor transcription activator family; Region: Mor; cl02360 413999015151 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999015152 NmrA-like family; Region: NmrA; pfam05368 413999015153 NAD(P) binding site [chemical binding]; other site 413999015154 active site 413999015155 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 413999015156 Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269 413999015157 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265 413999015158 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 413999015159 S-adenosylmethionine binding site [chemical binding]; other site 413999015160 Pfam match to entry PF05958 tRNA_U5-meth_tr, tRNA (Uracil-5-)-methyltransferase, score -128.6, E-value 2.2e-06 413999015161 PS01231 RNA methyltransferase trmA family signature 2. 413999015162 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015163 Pfam match to entry PF01938 TRAM, TRAM domain,score 43.5, E-value 5e-10 413999015164 Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561 413999015165 Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453 413999015166 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 413999015167 active site 413999015168 catalytic tetrad [active] 413999015169 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999015170 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 17.6, E-value 0.00042 413999015171 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999015172 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase, score 34.4, E-value 2.5e-11 413999015173 pyruvate kinase; Provisional; Region: PRK06354 413999015174 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342 413999015175 domain interfaces; other site 413999015176 active site 413999015177 Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848 413999015178 Pfam match to entry PF00391 PEP-utilizers,PEP-utilising enzyme, mobile domain, score 45.6, E-value 1.2e-10 413999015179 Pfam match to entry PF02887 PK_C, Pyruvate kinase,alpha/beta domain, score 142.0, E-value 1.1e-39 413999015180 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999015181 Pfam match to entry PF00224 PK, Pyruvate kinase,barrel domain, score 666.4, E-value 1.5e-197 413999015182 PS00110 Pyruvate kinase active site signature. 413999015183 6-phosphofructokinase; Provisional; Region: PRK03202 413999015184 6-phosphofructokinase; Region: PFKA_ATP; TIGR02482 413999015185 active site 413999015186 ADP/pyrophosphate binding site [chemical binding]; other site 413999015187 dimerization interface [polypeptide binding]; other site 413999015188 allosteric effector site; other site 413999015189 fructose-1,6-bisphosphate binding site; other site 413999015190 Pfam match to entry PF00365 PFK,Phosphofructokinase, score 547.1, E-value 1.3e-161 413999015191 PS00433 Phosphofructokinase signature. 413999015192 DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826 413999015193 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113 413999015194 active site 413999015195 PHP Thumb interface [polypeptide binding]; other site 413999015196 metal binding site [ion binding]; metal-binding site 413999015197 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 413999015198 generic binding surface II; other site 413999015199 generic binding surface I; other site 413999015200 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 36.8, E-value 5.1e-08 413999015201 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region, score 136.8, E-value 4.1e-38 413999015202 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region, score 117.5, E-value 2.7e-32 413999015203 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481 413999015204 Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298 413999015205 Pfam match to entry PF02650 DUF199, Uncharacterized BCR, COG1481, score 294.5, E-value 1.4e-85 413999015206 conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826 413999015207 family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187 413999015208 phosphate binding site [ion binding]; other site 413999015209 putative substrate binding pocket [chemical binding]; other site 413999015210 dimer interface [polypeptide binding]; other site 413999015211 Pfam match to entry PF01933 UPF0052,Uncharacterised protein family UPF0052, score 515.8,E-value 3.3e-152 413999015212 2 probable transmembrane helices predicted for CBO3376 by TMHMM2.0 at aa 15-32 and 39-61 413999015213 glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416 413999015214 Pfam match to entry PF03668 ATP_bind2, P-loop ATPase family, score 423.0, E-value 2.8e-124 413999015215 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015216 UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905 413999015217 FAD binding domain; Region: FAD_binding_4; pfam01565 413999015218 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873 413999015219 Pfam match to entry PF02873 MurB_C,UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain, score 152.4, E-value 8.1e-43 413999015220 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain, score 88.2, E-value 1.7e-23 413999015221 Histidinol phosphatase and related hydrolases of the PHP family [Amino acid transport and metabolism / General function prediction only]; Region: HIS2; COG1387 413999015222 Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437 413999015223 active site 413999015224 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region, score 28.6, E-value 1.5e-05 413999015225 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region, score 44.1, E-value 3.4e-10 413999015226 excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558 413999015227 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 413999015228 GIY-YIG motif/motif A; other site 413999015229 active site 413999015230 catalytic site [active] 413999015231 putative DNA binding site [nucleotide binding]; other site 413999015232 metal binding site [ion binding]; metal-binding site 413999015233 UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459 413999015234 Pfam match to entry PF02151 UVR, UvrB/uvrC motif,score 28.2, E-value 2e-05 413999015235 Pfam match to entry PF01541 Exci_endo_N,Endo/excinuclease amino terminal domain, score 110.1,E-value 4.6e-30 413999015236 Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307 413999015237 4 probable transmembrane helices predicted for CBO3381 by TMHMM2.0 at aa 13-35, 79-101, 108-130 and 176-198 413999015238 Pfam match to entry PF04307 DUF457, Predicted membrane-bound metal-dependent hydrolase (DUF457), score 92.1, E-value 1.2e-24 413999015239 YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492 413999015240 generic binding surface II; other site 413999015241 generic binding surface I; other site 413999015242 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 413999015243 Zn2+ binding site [ion binding]; other site 413999015244 Mg2+ binding site [ion binding]; other site 413999015245 Pfam match to entry PF01966 HD, HD domain, score 32.4, E-value 1.1e-06 413999015246 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 22.9, E-value 0.00082 413999015247 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 413999015248 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 413999015249 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 413999015250 Pfam match to entry PF00905 Transpeptidase,Penicillin binding protein transpeptidase domain, score 269.5, E-value 4.7e-78 413999015251 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015252 Pfam match to entry PF03717 PBP_dimer,Penicillin-binding Protein dimerisation domain, score 23.6, E-value 1.6e-06 413999015253 1 probable transmembrane helix predicted for CBO3383 by TMHMM2.0 at aa 12-34 413999015254 Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772 413999015255 Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein, score 275.6, E-value 6.6e-80 413999015256 12 probable transmembrane helices predicted for CBO3384 by TMHMM2.0 at aa 21-40, 45-67, 72-89, 99-116,128-145, 160-180, 187-206, 210-227, 234-252, 309-331,352-374 and 379-401 413999015257 Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060 413999015258 FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716 413999015259 phosphopeptide binding site; other site 413999015260 Pfam match to entry PF00498 FHA, FHA domain, score 77.5, E-value 2.9e-20 413999015261 1 probable transmembrane helix predicted for CBO3385 by TMHMM2.0 at aa 7-26 413999015262 excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349 413999015263 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 413999015264 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 413999015265 ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271 413999015266 Pfam match to entry PF00005 ABC_tran, ABC transporter score 95.9, E-value 8.5e-26 413999015267 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015268 Pfam match to entry PF00005 ABC_tran, ABC transporter score 9.4, E-value 8.4e-07 413999015269 PS00063 Aldo/keto reductase active site signature. 413999015270 PS00211 ABC transporters family signature. 413999015271 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015272 excinuclease ABC subunit B; Provisional; Region: PRK05298 413999015273 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999015274 ATP binding site [chemical binding]; other site 413999015275 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999015276 nucleotide binding region [chemical binding]; other site 413999015277 ATP-binding site [chemical binding]; other site 413999015278 Ultra-violet resistance protein B; Region: UvrB; pfam12344 413999015279 UvrB/uvrC motif; Region: UVR; pfam02151 413999015280 Pfam match to entry PF02151 UVR, UvrB/uvrC motif,score 51.0, E-value 2.8e-12 413999015281 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 76.7, E-value 4.9e-20 413999015282 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015283 7 probable transmembrane helices predicted for CBO3388 by TMHMM2.0 at aa 4-18, 39-61, 66-88, 93-115,125-147, 168-190 and 212-234 413999015284 C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526 413999015285 C-terminal peptidase (prc); Region: prc; TIGR00225 413999015286 PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988 413999015287 protein binding site [polypeptide binding]; other site 413999015288 C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560 413999015289 Catalytic dyad [active] 413999015290 Pfam match to entry PF03572 Peptidase_S41,Peptidase S41B, score 277.7, E-value 1.6e-80 413999015291 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF), score 48.4, E-value 1.7e-11 413999015292 1 probable transmembrane helix predicted for CBO3389 by TMHMM2.0 at aa 7-29 413999015293 Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177 413999015294 cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026 413999015295 Pfam match to entry PF02687 FtsX, Predicted permease, score 95.5, E-value 1.1e-25 413999015296 4 probable transmembrane helices predicted for CBO3390 by TMHMM2.0 at aa 23-45, 176-198, 219-241 and 268-290 413999015297 Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884 413999015298 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999015299 Walker A/P-loop; other site 413999015300 ATP binding site [chemical binding]; other site 413999015301 Q-loop/lid; other site 413999015302 ABC transporter signature motif; other site 413999015303 Walker B; other site 413999015304 D-loop; other site 413999015305 H-loop/switch region; other site 413999015306 Pfam match to entry PF00005 ABC_tran, ABC transporter score 213.0, E-value 4.8e-61 413999015307 PS00211 ABC transporters family signature. 413999015308 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015309 Uncharacterized conserved protein [Function unknown]; Region: COG1284 413999015310 Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588 413999015311 Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035 413999015312 6 probable transmembrane helices predicted for CBO3392 by TMHMM2.0 at aa 9-27, 37-59, 72-94, 109-129,150-172 and 177-199 413999015313 Pfam match to entry PF02588 DUF161, Uncharacterized BCR, YitT family COG1284, score 91.8, E-value 1.4e-24 413999015314 Pfam match to entry PF02588 DUF161, Uncharacterized BCR, YitT family COG1284, score 70.5, E-value 3.7e-18 413999015315 3 probable transmembrane helices predicted for CBO3393 by TMHMM2.0 at aa 15-33, 40-62 and 89-111 413999015316 Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958 413999015317 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 413999015318 PYR/PP interface [polypeptide binding]; other site 413999015319 dimer interface [polypeptide binding]; other site 413999015320 TPP binding site [chemical binding]; other site 413999015321 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 413999015322 Pfam match to entry PF02780 transketolase_C,Transketolase, C-terminal domain, score 144.9, E-value 1.5e-40 413999015323 Pfam match to entry PF02779 transket_pyr,Transketolase, pyridine binding domain, score 219.0,E-value 7.2e-63 413999015324 transketolase; Reviewed; Region: PRK05899 413999015325 Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012 413999015326 TPP-binding site [chemical binding]; other site 413999015327 dimer interface [polypeptide binding]; other site 413999015328 Pfam match to entry PF00456 transketolase,Transketolase, thiamine diphosphate binding domain, score 212.0, E-value 9.5e-61 413999015329 PS00801 Transketolase signature 1. 413999015330 PemK-like protein; Region: PemK; pfam02452 413999015331 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864 413999015332 Pfam match to entry PF01402 HTH_4,Ribbon-helix-helix protein, copG family, score 24.3,E-value 0.00031 413999015333 alanine racemase; Reviewed; Region: alr; PRK00053 413999015334 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430 413999015335 active site 413999015336 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 413999015337 dimer interface [polypeptide binding]; other site 413999015338 substrate binding site [chemical binding]; other site 413999015339 catalytic residues [active] 413999015340 Pfam match to entry PF00842 Ala_racemase_C, Alanine racemase, C-terminal domain, score 228.9, E-value 7.8e-66 413999015341 Pfam match to entry PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain, score 285.0, E-value 1e-82 413999015342 Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834 413999015343 1 probable transmembrane helix predicted for CBO3398 by TMHMM2.0 at aa 5-23 413999015344 YjeF-related protein N-terminus; Region: YjeF_N; pfam03853 413999015345 B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171 413999015346 putative substrate binding site [chemical binding]; other site 413999015347 putative ATP binding site [chemical binding]; other site 413999015348 Pfam match to entry PF01256 carb_kinase,Carbohydrate kinase, score 226.6, E-value 3.7e-65 413999015349 Pfam match to entry PF03853 YjeF_N, YjeF-related protein N-terminus, score 162.0, E-value 1.1e-45 413999015350 4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070 413999015351 Pfam match to entry PF01648 ACPS,4'-phosphopantetheinyl transferase superfamily, score 68.1, E-value 1.9e-17 413999015352 Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757 413999015353 C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; cl17322 413999015354 12 probable transmembrane helices predicted for CBO3402 by TMHMM2.0 at aa 12-30, 34-53, 73-90, 100-122,124-146, 150-172, 193-215, 230-252, 257-279, 289-308,329-351 and 404-426 413999015355 Pfam match to entry PF03553 Na_H_antiporter, Na+/H+ antiporter family, score 197.7, E-value 1.9e-56 413999015356 Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631 413999015357 Pfam match to entry PF03631 Ribonuclease_BN,Ribonuclease BN-like family, score 292.2, E-value 6.7e-85 413999015358 6 probable transmembrane helices predicted for CBO3403 by TMHMM2.0 at aa 32-54, 90-112, 133-155, 175-197,209-231 and 241-263 413999015359 30S ribosomal protein S4; Validated; Region: rpsD; PRK05327 413999015360 Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163 413999015361 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999015362 RNA binding surface [nucleotide binding]; other site 413999015363 Pfam match to entry PF01479 S4, S4 domain, score 85.4, E-value 1.2e-22 413999015364 Pfam match to entry PF00163 Ribosomal_S4, Ribosomal protein S4/S9 N-terminal domain, score 63.0, E-value 6.9e-16 413999015365 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 413999015366 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 413999015367 Pfam match to entry PF00375 SDF,Sodium:dicarboxylate symporter family, score -16.1,E-value 5.3e-09 413999015368 9 probable transmembrane helices predicted for CBO3406 by TMHMM2.0 at aa 7-29, 34-56, 69-91, 123-142,163-185, 200-222, 269-291, 306-328 and 333-355 413999015369 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 413999015370 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 413999015371 active site 413999015372 Pfam match to entry PF01569 PAP2, PAP2 superfamily,score 77.5, E-value 2.8e-20 413999015373 4 probable transmembrane helices predicted for CBO3407 by TMHMM2.0 at aa 26-48, 58-80, 124-143 and 148-167 413999015374 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 28.8, E-value 5e-06 413999015375 PS00217 Sugar transport proteins signature 2. 413999015376 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 413999015377 dinuclear metal binding motif [ion binding]; other site 413999015378 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 413999015379 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 413999015380 glutaminase active site [active] 413999015381 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 413999015382 dimer interface [polypeptide binding]; other site 413999015383 active site 413999015384 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 413999015385 dimer interface [polypeptide binding]; other site 413999015386 active site 413999015387 Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956 413999015388 active site 413999015389 intersubunit interactions; other site 413999015390 catalytic residue [active] 413999015391 Pfam match to entry PF00923 Transaldolase,Transaldolase, score 213.6, E-value 3e-61 413999015392 PS01054 Transaldolase signature 1. 413999015393 beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009 413999015394 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999015395 motif II; other site 413999015396 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 120.3, E-value 3.7e-33 413999015397 sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384 413999015398 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 413999015399 NAD(P) binding site [chemical binding]; other site 413999015400 active site 413999015401 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 275.9, E-value 5.6e-80 413999015402 PS00061 Short-chain dehydrogenases/reductases family signature. 413999015403 PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829 413999015404 Pfam match to entry PF03829 PTSIIA_gutA, PTS system glucitol/sorbitol-specific IIA component, score 170.2,E-value 3.5e-48 413999015405 Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732 413999015406 Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612 413999015407 Nucleoside recognition; Region: Gate; pfam07670 413999015408 Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663 413999015409 4 probable transmembrane helices predicted for CBO3415 by TMHMM2.0 at aa 161-180, 185-207, 214-236 and 315-334 413999015410 Pfam match to entry PF03612 EIIBC-GUT, Sorbitol phosphotransferase enzyme II, score 717.0, E-value 8.8e-213 413999015411 PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608 413999015412 Pfam match to entry PF03608 EII-GUT, PTS system enzyme II sorbitol-specific factor, score 434.6, E-value 9.2e-128 413999015413 2 probable transmembrane helices predicted for CBO3416 by TMHMM2.0 at aa 22-44 and 64-86 413999015414 Glucitol operon activator protein (GutM); Region: GutM; pfam06923 413999015415 1 probable transmembrane helix predicted for CBO3417 by TMHMM2.0 at aa 5-22 413999015416 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 413999015417 NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236 413999015418 putative NAD(P) binding site [chemical binding]; other site 413999015419 catalytic Zn binding site [ion binding]; other site 413999015420 Pfam match to entry PF00107 ADH_zinc_N,Zinc-binding dehydrogenase, score 350.3, E-value 2.2e-102 413999015421 PS00059 Zinc-containing alcohol dehydrogenases signature. 413999015422 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 413999015423 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 413999015424 non-specific DNA interactions [nucleotide binding]; other site 413999015425 DNA binding site [nucleotide binding] 413999015426 sequence specific DNA binding site [nucleotide binding]; other site 413999015427 putative cAMP binding site [chemical binding]; other site 413999015428 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 413999015429 Pfam match to entry PF04198 Sugar-bind, sugar-binding domain, score 310.6, E-value 2e-90 413999015430 phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316 413999015431 GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802 413999015432 active site 413999015433 substrate binding site [chemical binding]; other site 413999015434 metal binding site [ion binding]; metal-binding site 413999015435 Pfam match to entry PF00408 PGM_PMM,Phosphoglucomutase/phosphomannomutase, C-terminal domain,score 25.6, E-value 1.4e-05 413999015436 Pfam match to entry PF02880 PGM_PMM_III,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III, score 101.4, E-value 1.8e-27 413999015437 Pfam match to entry PF02879 PGM_PMM_II,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II, score 98.1, E-value 1.8e-26 413999015438 Pfam match to entry PF02878 PGM_PMM_I,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I, score 207.1, E-value 2.8e-59 413999015439 PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 413999015440 Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558 413999015441 Pfam match to entry PF01558 POR, Pyruvate ferredoxin/flavodoxin oxidoreductase, score 105.0, E-value 1.6e-28 413999015442 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013 413999015443 Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375 413999015444 TPP-binding site [chemical binding]; other site 413999015445 2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119 413999015446 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 413999015447 dimer interface [polypeptide binding]; other site 413999015448 PYR/PP interface [polypeptide binding]; other site 413999015449 TPP binding site [chemical binding]; other site 413999015450 substrate binding site [chemical binding]; other site 413999015451 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 413999015452 Pfam match to entry PF02780 transketolase_C,Transketolase, C-terminal domain, score -12.6, E-value 0.0093 413999015453 Pfam match to entry PF01855 POR_N, Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain, score 237.9, E-value 1.5e-68 413999015454 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 413999015455 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 413999015456 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 8.2, E-value 0.013 413999015457 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999015458 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 30.5, E-value 3.9e-06 413999015459 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999015460 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 413999015461 P-loop; other site 413999015462 Magnesium ion binding site [ion binding]; other site 413999015463 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015464 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 413999015465 nucleotide binding site [chemical binding]; other site 413999015466 Acetokinase family; Region: Acetate_kinase; cl17229 413999015467 Pfam match to entry PF00871 Acetate_kinase,Acetokinase, score 442.0, E-value 5.6e-130 413999015468 PS01075 Acetate and butyrate kinases family signature 1. 413999015469 phosphate butyryltransferase; Validated; Region: PRK05805 413999015470 Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase, score 335.8, E-value 5.1e-98 413999015471 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 413999015472 butyrate kinase; Provisional; Region: PRK03011 413999015473 Pfam match to entry PF00871 Acetate_kinase,Acetokinase, score 294.0, E-value 1.9e-85 413999015474 PS01075 Acetate and butyrate kinases family signature 1. 413999015475 Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509 413999015476 YbbR-like protein; Region: YbbR; pfam07949 413999015477 YbbR-like protein; Region: YbbR; pfam07949 413999015478 1 probable transmembrane helix predicted for CBO3430 by TMHMM2.0 at aa 9-28 413999015479 Uncharacterized conserved protein [Function unknown]; Region: COG1624 413999015480 DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457 413999015481 Pfam match to entry PF02457 DUF147, Domain of unknown function DUF147, score 205.7, E-value 7.3e-59 413999015482 2 probable transmembrane helices predicted for CBO3431 by TMHMM2.0 at aa 13-35 and 48-70 413999015483 Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486 413999015484 1 probable transmembrane helix predicted for CBO3432 by TMHMM2.0 at aa 5-22 413999015485 Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492 413999015486 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 413999015487 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase, score 62.4, E-value 1e-15 413999015488 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 413999015489 catalytic residues [active] 413999015490 Pfam match to entry PF00085 thiored, Thioredoxin,score 138.2, E-value 1.6e-38 413999015491 PS00194 Thioredoxin family active site. 413999015492 isoaspartyl dipeptidase; Provisional; Region: PRK10657 413999015493 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 413999015494 active site 413999015495 Pfam match to entry PF01979 Amidohydro_1,Amidohydrolase, score 10.4, E-value 5.1e-05 413999015496 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 413999015497 TPR motif; other site 413999015498 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999015499 binding surface 413999015500 1 probable transmembrane helix predicted for CBO3436 by TMHMM2.0 at aa 180-198 413999015501 Pfam match to entry PF00515 TPR, TPR Domain, score 46.8, E-value 5.2e-11 413999015502 Pfam match to entry PF00515 TPR, TPR Domain, score 13.3, E-value 0.098 413999015503 1 probable transmembrane helix predicted for CBO3437 by TMHMM2.0 at aa 7-24 413999015504 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999015505 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080 413999015506 PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524 413999015507 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 413999015508 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 413999015509 Pfam match to entry PF02896 PEP-utilizers_C,PEP-utilising enzyme, TIM barrel domain, score 574.4,E-value 7.6e-170 413999015510 PS00742 PEP-utilizing enzymes signature 2. 413999015511 Pfam match to entry PF00391 PEP-utilizers,PEP-utilising enzyme, mobile domain, score 130.8, E-value 2.5e-36 413999015512 PS00370 PEP-utilizing enzymes phosphorylation site signature. 413999015513 Pfam match to entry PF05524 PEP-utilisers_N,PEP-utilising enzyme, N-terminal, score 188.7, E-value 9.4e-54 413999015514 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 413999015515 dimerization domain swap beta strand [polypeptide binding]; other site 413999015516 regulatory protein interface [polypeptide binding]; other site 413999015517 active site 413999015518 regulatory phosphorylation site [posttranslational modification]; other site 413999015519 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829 413999015520 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999015521 putative active site [active] 413999015522 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 413999015523 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999015524 Walker A motif; other site 413999015525 ATP binding site [chemical binding]; other site 413999015526 Walker B motif; other site 413999015527 arginine finger; other site 413999015528 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 413999015529 Pfam match to entry PF00989 PAS, PAS domain, score 31.2, E-value 2.6e-06 413999015530 Pfam match to entry PF00989 PAS, PAS domain, score 35.6, E-value 1.2e-07 413999015531 Pfam match to entry PF00158 Sigma54_activat,Sigma-54 interaction domain, score 440.7, E-value 1.3e-129 413999015532 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413999015533 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413999015534 PS00688 Sigma-54 interaction domain C-terminal part signature. 413999015535 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 413999015536 TPR motif; other site 413999015537 binding surface 413999015538 Tetratricopeptide repeat; Region: TPR_12; pfam13424 413999015539 Pfam match to entry PF00515 TPR, TPR Domain, score 8.1, E-value 0.4 413999015540 Pfam match to entry PF00515 TPR, TPR Domain, score 23.7, E-value 0.00046 413999015541 Pfam match to entry PF00515 TPR, TPR Domain, score 20.9, E-value 0.0031 413999015542 Pfam match to entry PF00515 TPR, TPR Domain, score 6.2, E-value 0.69 413999015543 1 probable transmembrane helix predicted for CBO3440 by TMHMM2.0 at aa 21-40 413999015544 fumarate hydratase; Provisional; Region: PRK06842 413999015545 Pfam match to entry PF05683 Fumerase_C, Fumarase C-terminus, score 229.1, E-value 6.6e-66 413999015546 fumarate hydratase; Provisional; Region: PRK06246 413999015547 Pfam match to entry PF05681 Fumerase, Fumarate hydratase (Fumerase), score 550.2, E-value 1.5e-162 413999015548 PS00228 Tubulin-beta mRNA autoregulation signal. 413999015549 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 413999015550 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 413999015551 active site 413999015552 metal binding site [ion binding]; metal-binding site 413999015553 Pfam match to entry PF01520 Amidase_3,N-acetylmuramoyl-L-alanine amidase, score 83.9, E-value 3.5e-22 413999015554 1 probable transmembrane helix predicted for CBO3443 by TMHMM2.0 at aa 10-28 413999015555 Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283 413999015556 Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690 413999015557 Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690 413999015558 PhoU domain; Region: PhoU; pfam01895 413999015559 PhoU domain; Region: PhoU; pfam01895 413999015560 Pfam match to entry PF01895 PhoU, PhoU family,score 53.1, E-value 6.2e-13 413999015561 Pfam match to entry PF01895 PhoU, PhoU family,score 46.0, E-value 8.8e-11 413999015562 8 probable transmembrane helices predicted for CBO3444 by TMHMM2.0 at aa 4-23, 70-92, 102-124, 133-150,165-187, 194-216, 248-270 and 282-301 413999015563 Pfam match to entry PF02690 Na_Pi_cotrans,Na+/Pi-cotransporter score 41.7, E-value 3.5e-11 413999015564 Pfam match to entry PF02690 Na_Pi_cotrans,Na+/Pi-cotransporter score 195.2, E-value 1.1e-55 413999015565 30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132 413999015566 Pfam match to entry PF00380 Ribosomal_S9, Ribosomal protein S9/S16, score 227.1, E-value 2.8e-65 413999015567 PS00360 Ribosomal protein S9 signature. 413999015568 Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392 413999015569 23S rRNA interface [nucleotide binding]; other site 413999015570 L3 interface [polypeptide binding]; other site 413999015571 Pfam match to entry PF00572 Ribosomal_L13,Ribosomal protein L13, score 225.5, E-value 8.1e-65 413999015572 tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021 413999015573 Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA; Region: PseudoU_synth_EcTruA; cd02570 413999015574 dimerization interface 3.5A [polypeptide binding]; other site 413999015575 active site 413999015576 Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase, score 74.3, E-value 2.7e-19 413999015577 Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase, score 118.7, E-value 1.1e-32 413999015578 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 413999015579 4 probable transmembrane helices predicted for CBO3448 by TMHMM2.0 at aa 36-58, 73-95, 107-129 and 247-266 413999015580 Pfam match to entry PF02361 CbiQ, Cobalt transport protein, score 241.9, E-value 9.1e-70 413999015581 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 413999015582 cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13637 413999015583 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 413999015584 Walker A/P-loop; other site 413999015585 ATP binding site [chemical binding]; other site 413999015586 Q-loop/lid; other site 413999015587 ABC transporter signature motif; other site 413999015588 Walker B; other site 413999015589 D-loop; other site 413999015590 H-loop/switch region; other site 413999015591 Pfam match to entry PF00005 ABC_tran, ABC transporter score 224.4, E-value 1.7e-64 413999015592 PS00211 ABC transporters family signature. 413999015593 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015594 cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633 413999015595 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 413999015596 Walker A/P-loop; other site 413999015597 ATP binding site [chemical binding]; other site 413999015598 Q-loop/lid; other site 413999015599 ABC transporter signature motif; other site 413999015600 Walker B; other site 413999015601 D-loop; other site 413999015602 H-loop/switch region; other site 413999015603 Pfam match to entry PF00005 ABC_tran, ABC transporter score 166.1, E-value 6.3e-47 413999015604 PS00211 ABC transporters family signature. 413999015605 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015606 50S ribosomal protein L17; Validated; Region: rplQ; PRK05591 413999015607 Pfam match to entry PF01196 Ribosomal_L17,Ribosomal protein L17, score 187.5, E-value 2.2e-53 413999015608 PS01167 Ribosomal protein L17 signature. 413999015609 DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182 413999015610 N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928 413999015611 alphaNTD homodimer interface [polypeptide binding]; other site 413999015612 alphaNTD - beta interaction site [polypeptide binding]; other site 413999015613 alphaNTD - beta' interaction site [polypeptide binding]; other site 413999015614 Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118 413999015615 Pfam match to entry PF03118 RNA_pol_A_CTD,Bacterial RNA polymerase, alpha chain C terminal domain,score 123.1, E-value 5.6e-34 413999015616 Pfam match to entry PF01000 RNA_pol_A_bac, RNA polymerase Rpb3/RpoA insert domain, score 185.7, E-value 8e-53 413999015617 30S ribosomal protein S4; Validated; Region: rpsD; PRK05327 413999015618 Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163 413999015619 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999015620 RNA binding surface [nucleotide binding]; other site 413999015621 Pfam match to entry PF01479 S4, S4 domain, score 89.2, E-value 8.5e-24 413999015622 PS00632 Ribosomal protein S4 signature. 413999015623 Pfam match to entry PF00163 Ribosomal_S4, Ribosomal protein S4/S9 N-terminal domain, score 103.2, E-value 5.5e-28 413999015624 30S ribosomal protein S11; Validated; Region: PRK05309 413999015625 Pfam match to entry PF00411 Ribosomal_S11,Ribosomal protein S11, score 242.2, E-value 7.8e-70 413999015626 PS00054 Ribosomal protein S11 signature. 413999015627 30S ribosomal protein S13; Validated; Region: rpsM; PRK05179 413999015628 30S ribosomal protein S13; Region: bact_S13; TIGR03631 413999015629 Pfam match to entry PF00416 Ribosomal_S13,Ribosomal protein S13/S18, score 192.4, E-value 7.4e-55 413999015630 PS00646 Ribosomal protein S13 signature. 413999015631 50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465 413999015632 Pfam match to entry PF00444 Ribosomal_L36,Ribosomal protein L36, score 72.3, E-value 1.1e-18 413999015633 PS00828 Ribosomal protein L36 signature. 413999015634 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 413999015635 rRNA binding site [nucleotide binding]; other site 413999015636 predicted 30S ribosome binding site; other site 413999015637 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 45.4, E-value 1.4e-10 413999015638 KOW motif of Ribosomal Protein L14; Region: KOW_RPL14; cd06088 413999015639 RNA binding site [nucleotide binding]; other site 413999015640 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 413999015641 active site 413999015642 Pfam match to entry PF00557 Peptidase_M24,metallopeptidase M24, score 285.0, E-value 1e-82 413999015643 adenylate kinase; Reviewed; Region: adk; PRK00279 413999015644 Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428 413999015645 AMP-binding site [chemical binding]; other site 413999015646 ATP-AMP (Ap5A)-binding site [chemical binding]; other site 413999015647 Pfam match to entry PF00406 ADK, Adenylate kinase,score 297.6, E-value 1.6e-86 413999015648 Pfam match to entry PF05191 ADK_lid, Adenylate kinase, active site lid, score 79.9, E-value 5.4e-21 413999015649 PS00113 Adenylate kinase signature. 413999015650 preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204 413999015651 SecY translocase; Region: SecY; pfam00344 413999015652 Pfam match to entry PF00344 secY, eubacterial secY protein, score 405.7, E-value 4.6e-119 413999015653 10 probable transmembrane helices predicted for CBO3461 by TMHMM2.0 at aa 17-39, 54-76, 115-137, 147-164,171-193, 203-225, 262-284, 304-326, 363-385 and 389-408 413999015654 PS00756 Protein secY signature 2. 413999015655 PS00755 Protein secY signature 1. 413999015656 50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592 413999015657 Pfam match to entry PF00256 L15, Ribosomal protein L15, score 62.0, E-value 1.4e-15 413999015658 PS00475 Ribosomal protein L15 signature. 413999015659 Pfam match to entry PF01305 Ribosomal_L15,Ribosomal protein L15 amino terminal region, score 213.3,E-value 3.9e-61 413999015660 Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658 413999015661 23S rRNA binding site [nucleotide binding]; other site 413999015662 Pfam match to entry PF00327 Ribosomal_L30,Ribosomal protein L30p/L7e, score 54.1, E-value 3.1e-13 413999015663 30S ribosomal protein S5; Validated; Region: rpsE; PRK00550 413999015664 Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333 413999015665 Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719 413999015666 Pfam match to entry PF03719 Ribosomal_S5_C,Ribosomal protein S5, C-terminal domain, score 115.4,E-value 1.1e-31 413999015667 Pfam match to entry PF00333 Ribosomal_S5, Ribosomal protein S5, N-terminal domain, score 125.2, E-value 1.3e-34 413999015668 PS00585 Ribosomal protein S5 signature. 413999015669 Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432 413999015670 5S rRNA interface [nucleotide binding]; other site 413999015671 L27 interface [polypeptide binding]; other site 413999015672 23S rRNA interface [nucleotide binding]; other site 413999015673 L5 interface [polypeptide binding]; other site 413999015674 Pfam match to entry PF00861 Ribosomal_L18p,Ribosomal L18p/L5e family, score 185.9, E-value 6.7e-53 413999015675 50S ribosomal protein L6; Validated; Region: rplF; PRK05498 413999015676 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 413999015677 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 413999015678 Pfam match to entry PF00347 Ribosomal_L6, Ribosomal protein L6, score 111.1, E-value 2.3e-30 413999015679 PS00525 Ribosomal protein L6 signature 1. 413999015680 Pfam match to entry PF00347 Ribosomal_L6, Ribosomal protein L6, score 84.8, E-value 1.8e-22 413999015681 30S ribosomal protein S8; Validated; Region: rpsH; PRK00136 413999015682 Pfam match to entry PF00410 Ribosomal_S8, Ribosomal protein S8, score 234.1, E-value 2.1e-67 413999015683 PS00294 Prenyl group binding site (CAAX box). 413999015684 PS00053 Ribosomal protein S8 signature. 413999015685 30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061 413999015686 Pfam match to entry PF00253 Ribosomal_S14,Ribosomal protein S14p/S29e, score 109.8, E-value 5.4e-30 413999015687 50S ribosomal protein L5; Validated; Region: rplE; PRK00010 413999015688 Ribosomal protein L5; Region: Ribosomal_L5; pfam00281 413999015689 ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673 413999015690 Pfam match to entry PF00673 Ribosomal_L5_C,ribosomal L5P family C-terminus, score 181.9, E-value 1.1e-51 413999015691 Pfam match to entry PF00281 Ribosomal_L5, Ribosomal protein L5, score 126.0, E-value 7e-35 413999015692 PS00358 Ribosomal protein L5 signature. 413999015693 50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004 413999015694 KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089 413999015695 RNA binding site [nucleotide binding]; other site 413999015696 Pfam match to entry PF00467 KOW, KOW motif, score 38.1, E-value 2e-08 413999015697 50S ribosomal protein L14; Validated; Region: rplN; PRK05483 413999015698 Pfam match to entry PF00238 Ribosomal_L14,Ribosomal protein L14p/L23e, score 282.4, E-value 6.1e-82 413999015699 PS00049 Ribosomal protein L14 signature. 413999015700 30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610 413999015701 Pfam match to entry PF00366 Ribosomal_S17,Ribosomal protein S17, score 126.4, E-value 5.6e-35 413999015702 Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427 413999015703 23S rRNA interface [nucleotide binding]; other site 413999015704 putative translocon interaction site; other site 413999015705 signal recognition particle (SRP54) interaction site; other site 413999015706 L23 interface [polypeptide binding]; other site 413999015707 trigger factor interaction site; other site 413999015708 Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433 413999015709 23S rRNA interface [nucleotide binding]; other site 413999015710 5S rRNA interface [nucleotide binding]; other site 413999015711 putative antibiotic binding site [chemical binding]; other site 413999015712 L25 interface [polypeptide binding]; other site 413999015713 L27 interface [polypeptide binding]; other site 413999015714 Pfam match to entry PF00252 Ribosomal_L16,Ribosomal protein L16, score 316.5, E-value 3.4e-92 413999015715 PS00701 Ribosomal protein L16 signature 2. 413999015716 PS00586 Ribosomal protein L16 signature 1. 413999015717 30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310 413999015718 K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3 is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH...; Region: 30S_S3_KH; cd02412 413999015719 G-X-X-G motif; other site 413999015720 Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189 413999015721 Pfam match to entry PF00189 Ribosomal_S3_C,Ribosomal protein S3, C-terminal domain, score 171.0,E-value 2e-48 413999015722 PS00548 Ribosomal protein S3 signature. 413999015723 Pfam match to entry PF00013 KH, KH domain, score 34.7, E-value 2.3e-07 413999015724 Pfam match to entry PF00417 Ribosomal_S3_N,Ribosomal protein S3, N-terminal domain, score 113.2,E-value 5.3e-31 413999015725 Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336 413999015726 putative translocon binding site; other site 413999015727 protein-rRNA interface [nucleotide binding]; other site 413999015728 Pfam match to entry PF00237 Ribosomal_L22,Ribosomal protein L22p/L17e, score 186.8, E-value 3.5e-53 413999015729 PS00464 Ribosomal protein L22 signature. 413999015730 PS00962 Ribosomal protein S2 signature 1. 413999015731 30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357 413999015732 Pfam match to entry PF00203 Ribosomal_S19,Ribosomal protein S19, score 173.3, E-value 4.3e-49 413999015733 PS00323 Ribosomal protein S19 signature. 413999015734 50S ribosomal protein L2; Validated; Region: rplB; PRK09374 413999015735 Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181 413999015736 Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947 413999015737 Pfam match to entry PF03947 Ribosomal_L2_C,Ribosomal Proteins L2, C-terminal domain, score 293.3,E-value 3.3e-85 413999015738 PS00467 Ribosomal protein L2 signature. 413999015739 Pfam match to entry PF00181 Ribosomal_L2, Ribosomal Proteins L2, RNA binding domain, score 170.8, E-value 2.4e-48 413999015740 50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738 413999015741 Pfam match to entry PF00276 Ribosomal_L23,Ribosomal protein L23, score 132.4, E-value 8.5e-37 413999015742 PS00050 Ribosomal protein L23 signature. 413999015743 50S ribosomal protein L4; Provisional; Region: rplD; PRK05319 413999015744 Pfam match to entry PF00573 Ribosomal_L4, Ribosomal protein L4/L1 family, score 256.4, E-value 4.1e-74 413999015745 50S ribosomal protein L3; Validated; Region: rplC; PRK00001 413999015746 Pfam match to entry PF00297 Ribosomal_L3, Ribosomal protein L3, score 310.9, E-value 1.6e-90 413999015747 PS00474 Ribosomal protein L3 signature. 413999015748 30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596 413999015749 Pfam match to entry PF00338 Ribosomal_S10,Ribosomal protein S10p/S20e, score 215.5, E-value 8.2e-62 413999015750 PS00361 Ribosomal protein S10 signature. 413999015751 elongation factor Tu; Reviewed; Region: PRK00049 413999015752 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 413999015753 G1 box; other site 413999015754 GEF interaction site [polypeptide binding]; other site 413999015755 GTP/Mg2+ binding site [chemical binding]; other site 413999015756 Switch I region; other site 413999015757 G2 box; other site 413999015758 G3 box; other site 413999015759 Switch II region; other site 413999015760 G4 box; other site 413999015761 G5 box; other site 413999015762 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 413999015763 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 413999015764 Antibiotic Binding Site [chemical binding]; other site 413999015765 Pfam match to entry PF03143 GTP_EFTU_D3, Elongation factor Tu C-terminal domain, score 198.9, E-value 8.4e-57 413999015766 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 96.6, E-value 5e-26 413999015767 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 343.1, E-value 3.2e-100 413999015768 PS00301 GTP-binding elongation factors signature. 413999015769 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015770 elongation factor G; Reviewed; Region: PRK00007 413999015771 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 413999015772 G1 box; other site 413999015773 putative GEF interaction site [polypeptide binding]; other site 413999015774 GTP/Mg2+ binding site [chemical binding]; other site 413999015775 Switch I region; other site 413999015776 G2 box; other site 413999015777 G3 box; other site 413999015778 Switch II region; other site 413999015779 G4 box; other site 413999015780 G5 box; other site 413999015781 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 413999015782 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 413999015783 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 413999015784 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus, score 168.2, E-value 1.4e-47 413999015785 Pfam match to entry PF03764 EFG_IV, Elongation factor G, domain IV, score 229.8, E-value 4.2e-66 413999015786 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 413999015787 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 71.6, E-value 1.8e-18 413999015788 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 374.2, E-value 1.4e-109 413999015789 PS00301 GTP-binding elongation factors signature. 413999015790 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015791 30S ribosomal protein S7; Validated; Region: PRK05302 413999015792 Pfam match to entry PF00177 Ribosomal_S7, Ribosomal protein S7p/S5e, score 310.8, E-value 1.7e-90 413999015793 PS00052 Ribosomal protein S7 signature. 413999015794 S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368 413999015795 S17 interaction site [polypeptide binding]; other site 413999015796 S8 interaction site; other site 413999015797 16S rRNA interaction site [nucleotide binding]; other site 413999015798 streptomycin interaction site [chemical binding]; other site 413999015799 23S rRNA interaction site [nucleotide binding]; other site 413999015800 aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site 413999015801 Pfam match to entry PF00164 Ribosomal_S12,Ribosomal protein S12, score 262.6, E-value 5.6e-76 413999015802 PS00055 Ribosomal protein S12 signature. 413999015803 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600 413999015804 Pfam match to entry PF01248 Ribosomal_L7Ae,Ribosomal protein L7Ae/L30e/S12e/Gadd45 family, score 26.1, E-value 8.6e-05 413999015805 DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566 413999015806 RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997 413999015807 RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663 413999015808 RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983 413999015809 RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000 413999015810 Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655 413999015811 Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site 413999015812 G-loop; other site 413999015813 Apocytochrome F, C-terminal; Region: Apocytochr_F_C; cl03168 413999015814 Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655 413999015815 DNA binding site [nucleotide binding] 413999015816 Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site 413999015817 Pfam match to entry PF04998 RNA_pol_Rpb1_5, RNA polymerase Rpb1, domain 5, score 194.9, E-value 1.3e-55 413999015818 Pfam match to entry PF05000 RNA_pol_Rpb1_4, RNA polymerase Rpb1, domain 4, score 121.0, E-value 2.4e-33 413999015819 Pfam match to entry PF04983 RNA_pol_Rpb1_3, RNA polymerase Rpb1, domain 3, score 143.6, E-value 3.5e-40 413999015820 Pfam match to entry PF00623 RNA_pol_Rpb1_2, RNA polymerase Rpb1, domain 2, score 296.4, E-value 3.8e-86 413999015821 Pfam match to entry PF04997 RNA_pol_Rpb1_1, RNA polymerase Rpb1, domain 1, score 541.8, E-value 5.1e-160 413999015822 DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405 413999015823 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585 413999015824 RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561 413999015825 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 413999015826 RPB1 interaction site [polypeptide binding]; other site 413999015827 RPB10 interaction site [polypeptide binding]; other site 413999015828 RPB11 interaction site [polypeptide binding]; other site 413999015829 RPB3 interaction site [polypeptide binding]; other site 413999015830 RPB12 interaction site [polypeptide binding]; other site 413999015831 Pfam match to entry PF04560 RNA_pol_Rpb2_7, RNA polymerase Rpb2, domain 7, score 183.3, E-value 4.2e-52 413999015832 Pfam match to entry PF00562 RNA_pol_Rpb2_6, RNA polymerase Rpb2, domain 6, score 845.8, E-value 1.5e-251 413999015833 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015834 PS01166 RNA polymerases beta chain signature. 413999015835 Pfam match to entry PF04565 RNA_pol_Rpb2_3, RNA polymerase Rpb2, domain 3, score 162.7, E-value 6.3e-46 413999015836 Pfam match to entry PF04563 RNA_pol_Rpb2_1, RNA polymerase beta subunit, score 59.0, E-value 1.1e-14 413999015837 Pfam match to entry PF04561 RNA_pol_Rpb2_2, RNA polymerase Rpb2, domain 2, score 21.6, E-value 5.7e-07 413999015838 Pfam match to entry PF04561 RNA_pol_Rpb2_2, RNA polymerase Rpb2, domain 2, score 62.8, E-value 7.9e-16 413999015839 Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387 413999015840 core dimer interface [polypeptide binding]; other site 413999015841 peripheral dimer interface [polypeptide binding]; other site 413999015842 L10 interface [polypeptide binding]; other site 413999015843 L11 interface [polypeptide binding]; other site 413999015844 putative EF-Tu interaction site [polypeptide binding]; other site 413999015845 putative EF-G interaction site [polypeptide binding]; other site 413999015846 Pfam match to entry PF00542 Ribosomal_L12,Ribosomal protein L7/L12 C-terminal domain, score 137.3,E-value 2.8e-38 413999015847 Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797 413999015848 23S rRNA interface [nucleotide binding]; other site 413999015849 Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site 413999015850 Pfam match to entry PF00466 Ribosomal_L10,Ribosomal protein L10, score 90.6, E-value 3.3e-24 413999015851 Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403 413999015852 mRNA/rRNA interface [nucleotide binding]; other site 413999015853 Pfam match to entry PF00687 Ribosomal_L1, Ribosomal protein L1p/L10e family, score 453.5, E-value 1.9e-133 413999015854 PS01199 Ribosomal protein L1 signature. 413999015855 50S ribosomal protein L11; Validated; Region: rplK; PRK00140 413999015856 Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349 413999015857 23S rRNA interface [nucleotide binding]; other site 413999015858 L7/L12 interface [polypeptide binding]; other site 413999015859 putative thiostrepton binding site; other site 413999015860 L25 interface [polypeptide binding]; other site 413999015861 Pfam match to entry PF00298 Ribosomal_L11,Ribosomal protein L11, RNA binding domain, score 139.1,E-value 8.5e-39 413999015862 Pfam match to entry PF03946 Ribosomal_L11_N,Ribosomal protein L11, N-terminal domain, score 133.3,E-value 4.5e-37 413999015863 transcription antitermination protein NusG; Validated; Region: nusG; PRK05609 413999015864 Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891 413999015865 putative homodimer interface [polypeptide binding]; other site 413999015866 NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091 413999015867 heterodimer interface [polypeptide binding]; other site 413999015868 homodimer interface [polypeptide binding]; other site 413999015869 PS01014 Transcription termination factor nusG signature. 413999015870 Pfam match to entry PF00467 KOW, KOW motif, score 36.1, E-value 8.4e-08 413999015871 Pfam match to entry PF02357 NusG, Transcription termination factor nusG, score 62.9, E-value 7.2e-16 413999015872 SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584 413999015873 Pfam match to entry PF00584 SecE, SecE/Sec61-gamma subunits of protein translocation complex, score 43.6,E-value 4.8e-10 413999015874 1 probable transmembrane helix predicted for CBO3494 by TMHMM2.0 at aa 50-72 413999015875 50S ribosomal protein L33; Validated; Region: rpmG; PRK00504 413999015876 Pfam match to entry PF00471 Ribosomal_L33,Ribosomal protein L33, score 87.8, E-value 2.3e-23 413999015877 PS00582 Ribosomal protein L33 signature. 413999015878 elongation factor Tu; Reviewed; Region: PRK00049 413999015879 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 413999015880 G1 box; other site 413999015881 GEF interaction site [polypeptide binding]; other site 413999015882 GTP/Mg2+ binding site [chemical binding]; other site 413999015883 Switch I region; other site 413999015884 G2 box; other site 413999015885 G3 box; other site 413999015886 Switch II region; other site 413999015887 G4 box; other site 413999015888 G5 box; other site 413999015889 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 413999015890 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 413999015891 Antibiotic Binding Site [chemical binding]; other site 413999015892 Pfam match to entry PF03143 GTP_EFTU_D3, Elongation factor Tu C-terminal domain, score 198.9, E-value 8.4e-57 413999015893 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 96.6, E-value 5e-26 413999015894 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 343.1, E-value 3.2e-100 413999015895 PS00301 GTP-binding elongation factors signature. 413999015896 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015897 RNA polymerase sigma-H factor; Region: spore_sigH; TIGR02859 413999015898 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 413999015899 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 413999015900 PS00622 Bacterial regulatory proteins, luxR family signature. 413999015901 Pfam match to entry PF04542 sigma70_r2, Sigma-70 region 2, score 58.4, E-value 1.7e-14 413999015902 YacP-like NYN domain; Region: NYN_YacP; pfam05991 413999015903 Pfam match to entry PF05991 DUF901, Protein of unknown function (DUF901), score 233.3, E-value 3.6e-67 413999015904 rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566 413999015905 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967 413999015906 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 413999015907 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase, score 173.1, E-value 5e-49 413999015908 FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847 413999015909 Pfam match to entry PF02511 Thy1, Thymidylate synthase complementing protein, score 178.0, E-value 1.6e-50 413999015910 Ribonuclease III family protein [Replication, recombination, and repair]; Region: COG1939 413999015911 dimerization interface [polypeptide binding]; other site 413999015912 active site 413999015913 metal binding site [ion binding]; metal-binding site 413999015914 cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260 413999015915 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 413999015916 active site 413999015917 HIGH motif; other site 413999015918 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 413999015919 KMSKS motif; other site 413999015920 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 413999015921 tRNA binding surface [nucleotide binding]; other site 413999015922 anticodon binding site; other site 413999015923 Pfam match to entry PF01406 tRNA-synt_1e, tRNA synthetases class I (C), score 753.2, E-value 1.1e-223 413999015924 threonine dehydratase; Provisional; Region: PRK08198 413999015925 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 413999015926 tetramer interface [polypeptide binding]; other site 413999015927 pyridoxal 5'-phosphate binding site [chemical binding]; other site 413999015928 catalytic residue [active] 413999015929 C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886 413999015930 Pfam match to entry PF01842 ACT, ACT domain, score 17.1, E-value 0.043 413999015931 Pfam match to entry PF00291 PALP,Pyridoxal-phosphate dependent enzyme, score 296.7, E-value 3.1e-86 413999015932 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 413999015933 prolyl-tRNA synthetase; Provisional; Region: PRK09194 413999015934 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 413999015935 motif 1; other site 413999015936 dimer interface [polypeptide binding]; other site 413999015937 active site 413999015938 motif 2; other site 413999015939 INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334 413999015940 putative deacylase active site [active] 413999015941 ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861 413999015942 anticodon binding site; other site 413999015943 Pfam match to entry PF03129 HGTP_anticodon,Anticodon binding domain, score 81.2, E-value 2.2e-21 413999015944 Pfam match to entry PF04073 YbaK, YbaK / prolyl-tRNA synthetases associated domain, score 48.7,E-value 1.4e-11 413999015945 CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516 413999015946 substrate binding site; other site 413999015947 dimer interface; other site 413999015948 Pfam match to entry PF01128 IspD, Uncharacterized protein family UPF0007, score 206.8, E-value 3.6e-59 413999015949 PS01295 Uncharacterized protein family UPF0007 signature. 413999015950 Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956 413999015951 PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877 413999015952 putative active site [active] 413999015953 Pfam match to entry PF01938 TRAM, TRAM domain,score 19.4, E-value 0.0022 413999015954 Pfam match to entry PF01850 PIN, PIN domain, score 72.4, E-value 1e-18 413999015955 4 probable transmembrane helices predicted for CBO3505 by TMHMM2.0 at aa 9-31, 46-68, 89-111 and 115-137 413999015956 DNA integrity scanning protein DisA; Provisional; Region: PRK13482 413999015957 DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457 413999015958 DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635 413999015959 Pfam match to entry PF00633 HHH,Helix-hairpin-helix motif, score 20.5, E-value 0.0041 413999015960 Pfam match to entry PF02457 DUF147, Domain of unknown function DUF147, score 133.6, E-value 3.6e-37 413999015961 DNA repair protein RadA; Provisional; Region: PRK11823 413999015962 Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121 413999015963 Walker A motif/ATP binding site; other site 413999015964 ATP binding site [chemical binding]; other site 413999015965 Walker B motif; other site 413999015966 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 413999015967 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015968 ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542 413999015969 Clp amino terminal domain; Region: Clp_N; pfam02861 413999015970 Clp amino terminal domain; Region: Clp_N; pfam02861 413999015971 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999015972 Walker A motif; other site 413999015973 ATP binding site [chemical binding]; other site 413999015974 Walker B motif; other site 413999015975 arginine finger; other site 413999015976 UvrB/uvrC motif; Region: UVR; pfam02151 413999015977 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999015978 Walker A motif; other site 413999015979 ATP binding site [chemical binding]; other site 413999015980 Walker B motif; other site 413999015981 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 413999015982 PS00871 Chaperonins clpA/B signature 2. 413999015983 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015984 Pfam match to entry PF02151 UVR, UvrB/uvrC motif,score 41.2, E-value 2.4e-09 413999015985 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 52.0, E-value 1.4e-12 413999015986 PS00870 Chaperonins clpA/B signature 1. 413999015987 PS00017 ATP/GTP-binding site motif A (P-loop). 413999015988 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain, score 66.6, E-value 5.6e-17 413999015989 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain, score 65.9, E-value 9.2e-17 413999015990 ATP:guanido phosphotransferase; Provisional; Region: PRK01059 413999015991 Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930 413999015992 ADP binding site [chemical binding]; other site 413999015993 phosphagen binding site; other site 413999015994 substrate specificity loop; other site 413999015995 Pfam match to entry PF00217 ATP-gua_Ptrans,ATP:guanido phosphotransferase, C-terminal catalytic domain, score 30.9, E-value 1.7e-15 413999015996 PS00230 Neuraxin and MAP1B proteins repeated region signature. 413999015997 PS00112 ATP:guanido phosphotransferases active site. 413999015998 Modulator of heat shock repressor CtsR, McsA [Signal transduction mechanisms]; Region: COG3880 413999015999 Pfam match to entry PF02151 UVR, UvrB/uvrC motif,score 38.5, E-value 1.6e-08 413999016000 Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848 413999016001 Pfam match to entry PF05848 CtsR, Firmicute transcriptional repressor of class III stress genes (CtsR), score 242.2, E-value 7.5e-70 413999016002 Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170 413999016003 elongation factor G; Reviewed; Region: PRK12740 413999016004 G1 box; other site 413999016005 putative GEF interaction site [polypeptide binding]; other site 413999016006 GTP/Mg2+ binding site [chemical binding]; other site 413999016007 Switch I region; other site 413999016008 G2 box; other site 413999016009 G3 box; other site 413999016010 Switch II region; other site 413999016011 G4 box; other site 413999016012 G5 box; other site 413999016013 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 413999016014 Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789 413999016015 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 413999016016 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus, score 119.4, E-value 7e-33 413999016017 Pfam match to entry PF03764 EFG_IV, Elongation factor G, domain IV, score 224.6, E-value 1.6e-64 413999016018 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2, score 35.9, E-value 9.7e-08 413999016019 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain, score 189.8, E-value 4.6e-54 413999016020 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016021 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01710 413999016022 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 413999016023 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999016024 Quinolinate phosphoribosyl transferase, C-terminal domain; Region: QRPTase_C; pfam01729 413999016025 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain, score 15.1,E-value 0.0043 413999016026 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 118.4, E-value 1.4e-32 413999016027 glycyl-tRNA synthetase; Provisional; Region: PRK04173 413999016028 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 413999016029 motif 1; other site 413999016030 Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774 413999016031 active site 413999016032 motif 2; other site 413999016033 motif 3; other site 413999016034 GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858 413999016035 anticodon binding site; other site 413999016036 Pfam match to entry PF03129 HGTP_anticodon,Anticodon binding domain, score 115.1, E-value 1.4e-31 413999016037 PS00307 Legume lectins beta-chain signature. 413999016038 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T), score 210.5, E-value 2.7e-60 413999016039 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999016040 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016041 lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484 413999016042 LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322 413999016043 dimer interface [polypeptide binding]; other site 413999016044 putative anticodon binding site; other site 413999016045 Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775 413999016046 motif 1; other site 413999016047 active site 413999016048 motif 2; other site 413999016049 motif 3; other site 413999016050 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N), score 590.2, E-value 1.3e-174 413999016051 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 413999016052 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 413999016053 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain, score 75.1, E-value 1.5e-19 413999016054 transcription elongation factor GreA; Reviewed; Region: greA; PRK00226 413999016055 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 413999016056 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 413999016057 Pfam match to entry PF01272 GreA_GreB, Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain, score 83.5, E-value 4.6e-22 413999016058 PS00830 Prokaryotic transcription elongation factors signature 2. 413999016059 Pfam match to entry PF03449 GreA_GreB_N,Prokaryotic transcription elongation factor, GreA/GreB,N-terminal domain, score 106.9, E-value 4.2e-29 413999016060 PS00829 Prokaryotic transcription elongation factors signature 1. 413999016061 putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737 413999016062 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 413999016063 FMN binding site [chemical binding]; other site 413999016064 active site 413999016065 catalytic residues [active] 413999016066 substrate binding site [chemical binding]; other site 413999016067 Pfam match to entry PF01207 Dus, Dihydrouridine synthase (Dus), score 345.5, E-value 6e-101 413999016068 PS01136 Uncharacterized protein family UPF0034 signature. 413999016069 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 413999016070 nucleotide binding site [chemical binding]; other site 413999016071 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 413999016072 Pfam match to entry PF03309 Bvg_acc_factor,Bordetella pertussis Bvg accessory factor family, score 271.9, E-value 8.6e-79 413999016073 formate--tetrahydrofolate ligase; Provisional; Region: PRK13505 413999016074 Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477 413999016075 Potassium binding sites [ion binding]; other site 413999016076 Cesium cation binding sites [ion binding]; other site 413999016077 Pfam match to entry PF01268 FTHFS,Formate--tetrahydrofolate ligase, score 1139.6, E-value 0 413999016078 PS00722 Formate--tetrahydrofolate ligase signature 2. 413999016079 PS00721 Formate--tetrahydrofolate ligase signature 1. 413999016080 FtsH Extracellular; Region: FtsH_ext; pfam06480 413999016081 ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241 413999016082 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999016083 Walker A motif; other site 413999016084 ATP binding site [chemical binding]; other site 413999016085 Walker B motif; other site 413999016086 arginine finger; other site 413999016087 Peptidase family M41; Region: Peptidase_M41; pfam01434 413999016088 Pfam match to entry PF01434 Peptidase_M41,Peptidase M41, score 372.2, E-value 5.6e-109 413999016089 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 330.0, E-value 2.8e-96 413999016090 PS00674 AAA-protein family signature. 413999016091 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016092 2 probable transmembrane helices predicted for CBO3524 by TMHMM2.0 at aa 6-25 and 104-126 413999016093 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999016094 active site 413999016095 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 116.4, E-value 5.7e-32 413999016096 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 413999016097 tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037 413999016098 N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992 413999016099 Ligand Binding Site [chemical binding]; other site 413999016100 TilS substrate C-terminal domain; Region: TilS_C; smart00977 413999016101 Pfam match to entry PF01171 ATP_bind3, PP-loop family, score 288.3, E-value 1e-83 413999016102 stage II sporulation protein E; Region: spore_II_E; TIGR02865 413999016103 Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228 413999016104 8 probable transmembrane helices predicted for CBO3527 by TMHMM2.0 at aa 27-49, 72-94, 119-141, 148-170,185-204, 211-233, 248-265 and 286-308 413999016105 hypothetical protein; Provisional; Region: PRK05807 413999016106 S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927 413999016107 RNA binding site [nucleotide binding]; other site 413999016108 Pfam match to entry PF00575 S1, S1 RNA binding domain, score 91.4, E-value 1.9e-24 413999016109 Septum formation initiator; Region: DivIC; pfam04977 413999016110 Pfam match to entry PF04977 DivIC, Septum formation initiator, score 68.9, E-value 1.1e-17 413999016111 1 probable transmembrane helix predicted for CBO3530 by TMHMM2.0 at aa 9-28 413999016112 Spore cortex protein YabQ (Spore_YabQ); Region: Spore_YabQ; cl09801 413999016113 4 probable transmembrane helices predicted for CBO3531 by TMHMM2.0 at aa 12-29, 44-66, 73-95 and 110-127 413999016114 sporulation protein YabP; Region: spore_yabP; TIGR02892 413999016115 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 413999016116 RNA binding surface [nucleotide binding]; other site 413999016117 Pfam match to entry PF01479 S4, S4 domain, score 48.4, E-value 1.6e-11 413999016118 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 413999016119 IHF dimer interface [polypeptide binding]; other site 413999016120 IHF - DNA interface [nucleotide binding]; other site 413999016121 Pfam match to entry PF00216 Bac_DNA_binding,Bacterial DNA-binding protein, score 165.3, E-value 1.1e-46 413999016122 PS00045 Bacterial histone-like DNA-binding proteins signature. 413999016123 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only]; Region: COG3956 413999016124 N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723 413999016125 putative SAM binding site [chemical binding]; other site 413999016126 putative homodimer interface [polypeptide binding]; other site 413999016127 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528 413999016128 homodimer interface [polypeptide binding]; other site 413999016129 metal binding site [ion binding]; metal-binding site 413999016130 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529 413999016131 homodimer interface [polypeptide binding]; other site 413999016132 active site 413999016133 putative chemical substrate binding site [chemical binding]; other site 413999016134 metal binding site [ion binding]; metal-binding site 413999016135 Pfam match to entry PF03819 MazG, MazG nucleotide pyrophosphohydrolase domain, score 52.7, E-value 8.7e-13 413999016136 Pfam match to entry PF03819 MazG, MazG nucleotide pyrophosphohydrolase domain, score 125.4, E-value 1.1e-34 413999016137 Pfam match to entry PF00590 TP_methylase,Tetrapyrrole (Corrin/Porphyrin) Methylases, score 29.2,E-value 5.9e-07 413999016138 stage V sporulation protein B; Region: spore_V_B; TIGR02900 413999016139 Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124 413999016140 14 probable transmembrane helices predicted for CBO3536 by TMHMM2.0 at aa 9-31, 46-68, 89-106, 121-143,164-181, 186-208, 225-247, 277-299, 315-337, 357-379,386-405, 410-432, 445-467 and 477-499 413999016141 Pfam match to entry PF01943 Polysacc_synt,Polysaccharide biosynthesis protein, score 89.7, E-value 6e-24 413999016142 stage V sporulation protein T; Region: spore_V_T; TIGR02851 413999016143 looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439 413999016144 Pfam match to entry PF04014 SpoVT_AbrB, SpoVT / AbrB like domain, score 53.2, E-value 6e-13 413999016145 peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059 413999016146 SurA N-terminal domain; Region: SurA_N_3; cl07813 413999016147 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 413999016148 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain, score 118.0, E-value 1.8e-32 413999016149 PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 413999016150 1 probable transmembrane helix predicted for CBO3538 by TMHMM2.0 at aa 7-26 413999016151 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016152 Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197 413999016153 CarD-like/TRCF domain; Region: CarD_TRCF; smart01058 413999016154 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 413999016155 ATP binding site [chemical binding]; other site 413999016156 putative Mg++ binding site [ion binding]; other site 413999016157 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 413999016158 nucleotide binding region [chemical binding]; other site 413999016159 ATP-binding site [chemical binding]; other site 413999016160 TRCF domain; Region: TRCF; pfam03461 413999016161 Pfam match to entry PF03461 TRCF, TRCF domain,score 103.1, E-value 5.9e-28 413999016162 Pfam match to entry PF00271 helicase_C, Helicase C-terminal domain, score 76.6, E-value 5.4e-20 413999016163 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 148.3, E-value 1.4e-41 413999016164 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016165 Pfam match to entry PF02559 CarD_TRCF,CarD-like/TRCF domain, score 180.3, E-value 3.3e-51 413999016166 PS01118 Translation initiation factor SUI1 signature. 413999016167 Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462 413999016168 putative active site [active] 413999016169 catalytic residue [active] 413999016170 Pfam match to entry PF01195 Pept_tRNA_hydro,Peptidyl-tRNA hydrolase, score 288.1, E-value 1.2e-83 413999016171 PS01196 Peptidyl-tRNA hydrolase signature 2. 413999016172 PS01195 Peptidyl-tRNA hydrolase signature 1. 413999016173 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 413999016174 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 413999016175 protein binding site [polypeptide binding]; other site 413999016176 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF), score 56.4, E-value 6.7e-14 413999016177 Pfam match to entry PF00089 trypsin, Trypsin, score 75.0, E-value 1.6e-19 413999016178 1 probable transmembrane helix predicted for CBO3541 by TMHMM2.0 at aa 36-58 413999016179 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 413999016180 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 413999016181 dimerization interface [polypeptide binding]; other site 413999016182 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 413999016183 dimer interface [polypeptide binding]; other site 413999016184 phosphorylation site [posttranslational modification] 413999016185 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 413999016186 ATP binding site [chemical binding]; other site 413999016187 Mg2+ binding site [ion binding]; other site 413999016188 G-X-G motif; other site 413999016189 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, score 121.6, E-value 1.5e-33 413999016190 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain, score 81.6, E-value 1.6e-21 413999016191 Pfam match to entry PF00672 HAMP, HAMP domain,score 69.0, E-value 1.1e-17 413999016192 2 probable transmembrane helices predicted for CBO3542 by TMHMM2.0 at aa 10-32 and 169-191 413999016193 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016194 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 413999016195 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 413999016196 active site 413999016197 phosphorylation site [posttranslational modification] 413999016198 intermolecular recognition site; other site 413999016199 dimerization interface [polypeptide binding]; other site 413999016200 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 413999016201 DNA binding site [nucleotide binding] 413999016202 Pfam match to entry PF00486 trans_reg_C,Transcriptional regulatory protein, C terminal, score 98.6, E-value 1.3e-26 413999016203 Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 141.0, E-value 2.1e-39 413999016204 ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259 413999016205 N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793 413999016206 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999016207 active site 413999016208 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 123.8, E-value 3.3e-34 413999016209 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 413999016210 PS00114 Phosphoribosyl pyrophosphate synthetase signature. 413999016211 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354 413999016212 N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540 413999016213 Substrate binding site; other site 413999016214 Mg++ binding site; other site 413999016215 N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353 413999016216 active site 413999016217 substrate binding site [chemical binding]; other site 413999016218 CoA binding site [chemical binding]; other site 413999016219 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 8.1,E-value 10 413999016220 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 9.8,E-value 6.5 413999016221 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016222 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 4.3,E-value 29 413999016223 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.0,E-value 6 413999016224 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 10.9,E-value 3.3 413999016225 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 8.0,E-value 10 413999016226 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (three repeats), score 20.6,E-value 0.0039 413999016227 Pfam match to entry PF00483 NTP_transferase,Nucleotidyl transferase, score 33.8, E-value 6.9e-13 413999016228 regulatory protein SpoVG; Reviewed; Region: PRK13259 413999016229 Pfam match to entry PF04026 SpoVG, SpoVG, score 220.2, E-value 3.2e-63 413999016230 pur operon repressor; Provisional; Region: PRK09213 413999016231 Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182 413999016232 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 413999016233 active site 413999016234 Pfam match to entry PF00156 Pribosyltran,Phosphoribosyl transferase domain, score 72.8, E-value 7.4e-19 413999016235 UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421 413999016236 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 413999016237 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 413999016238 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 413999016239 1 probable transmembrane helix predicted for CBO3548 by TMHMM2.0 at aa 13-32 413999016240 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain, score 189.5, E-value 5.4e-54 413999016241 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain, score 107.3,E-value 3e-29 413999016242 3 probable transmembrane helices predicted for CBO3549 by TMHMM2.0 at aa 5-27, 42-64 and 71-93 413999016243 Iron only hydrogenase large subunit, C-terminal domain [General function prediction only]; Region: COG4624 413999016244 4Fe-4S binding domain; Region: Fer4; pfam00037 413999016245 Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906 413999016246 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 38.2, E-value 1.9e-08 413999016247 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999016248 Pfam match to entry PF02906 Fe_hyd_lg_C, Iron only hydrogenase large subunit, C-terminal domain, score -30.4,E-value 5.7e-15 413999016249 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 413999016250 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 413999016251 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 413999016252 motif II; other site 413999016253 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 88.9, E-value 1.1e-23 413999016254 1 probable transmembrane helix predicted for CBO3552 by TMHMM2.0 at aa 5-27 413999016255 2-phosphosulfolactate phosphatase; Provisional; Region: PRK00886 413999016256 Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Region: COG2045 413999016257 Pfam match to entry PF04029 2-ph_phosp,2-phosphosulpholactate phosphatase, score 277.7, E-value 1.5e-80 413999016258 Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242 413999016259 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999016260 FeS/SAM binding site; other site 413999016261 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 69.4, E-value 8.2e-18 413999016262 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016263 Uncharacterized membrane protein [Function unknown]; Region: COG3949 413999016264 10 probable transmembrane helices predicted for CBO3556 by TMHMM2.0 at aa 7-29, 44-61, 82-104, 114-135,144-166, 186-208, 221-243, 263-285, 297-319 and 323-345 413999016265 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins [General function prediction only]; Region: PflX; COG1313 413999016266 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999016267 FeS/SAM binding site; other site 413999016268 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 32.3, E-value 1.2e-06 413999016269 Heme NO binding; Region: HNOB; pfam07700 413999016270 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 413999016271 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 413999016272 dimer interface [polypeptide binding]; other site 413999016273 putative CheW interface [polypeptide binding]; other site 413999016274 Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, score 76.8, E-value 4.6e-20 413999016275 1 probable transmembrane helix predicted for CBO3558 by TMHMM2.0 at aa 201-223 413999016276 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 413999016277 non-specific DNA binding site [nucleotide binding]; other site 413999016278 salt bridge; other site 413999016279 sequence-specific DNA binding site [nucleotide binding]; other site 413999016280 Pfam match to entry PF01381 HTH_3,Helix-turn-helix, score 58.9, E-value 1.2e-14 413999016281 Domain of unknown function (DUF3783); Region: DUF3783; pfam12646 413999016282 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 413999016283 cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317 413999016284 active site 413999016285 Pfam match to entry PF00160 pro_isomerase,Cyclophilin type peptidyl-prolyl cis-trans isomerase,score 171.3, E-value 1.7e-48 413999016286 PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 413999016287 glutamate racemase; Provisional; Region: PRK00865 413999016288 Pfam match to entry PF01177 Asp_Glu_race,Asp/Glu/Hydantoin racemase, score 238.3, E-value 1.2e-68 413999016289 PS00924 Aspartate and glutamate racemases signature 2. 413999016290 PS00923 Aspartate and glutamate racemases signature 1. 413999016291 glutamine synthetase, type I; Region: GlnA; TIGR00653 413999016292 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 413999016293 Pfam match to entry PF00120 gln-synt, Glutamine synthetase, catalytic domain, score 85.0, E-value 1.6e-22 413999016294 2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514 413999016295 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 413999016296 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 413999016297 hinge; other site 413999016298 active site 413999016299 Pfam match to entry PF00275 EPSP_synthase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase),score 398.4, E-value 7.2e-117 413999016300 Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235 413999016301 Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily, score 65.8, E-value 9.9e-17 413999016302 Sporulation and spore germination; Region: Germane; pfam10646 413999016303 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016304 hypothetical protein; Provisional; Region: PRK05590 413999016305 SEC-C motif; Region: SEC-C; pfam02810 413999016306 Pfam match to entry PF02810 SEC-C, SEC-C motif,score 41.5, E-value 1.9e-09 413999016307 rRNA large subunit methyltransferase; Provisional; Region: PRK00103 413999016308 Pfam match to entry PF02590 DUF163, Uncharacterized ACR, COG1576, score 329.6, E-value 3.7e-96 413999016309 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016310 1 probable transmembrane helix predicted for CBO3571 by TMHMM2.0 at aa 7-29 413999016311 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 413999016312 Major Facilitator Superfamily; Region: MFS_1; pfam07690 413999016313 putative substrate translocation pore; other site 413999016314 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter score -101.3, E-value 0.0012 413999016315 12 probable transmembrane helices predicted for CBO3572 by TMHMM2.0 at aa 27-49, 64-86, 93-112, 117-139,152-174, 179-201, 233-255, 265-287, 294-313, 317-336,353-375 and 379-398 413999016316 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016317 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 413999016318 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 413999016319 Pfam match to entry PF03358 FMN_red,NADPH-dependent FMN reductase, score 25.1, E-value 5e-07 413999016320 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 413999016321 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 413999016322 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family, score 69.7, E-value 6.6e-18 413999016323 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999016324 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 413999016325 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 413999016326 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 26.5, E-value 6.5e-05 413999016327 PS00041 Bacterial regulatory proteins, araC family signature. 413999016328 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family, score 39.6, E-value 7.4e-09 413999016329 methionine aminopeptidase; Provisional; Region: PRK12318 413999016330 SEC-C motif; Region: SEC-C; pfam02810 413999016331 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 413999016332 active site 413999016333 Pfam match to entry PF02810 SEC-C, SEC-C motif,score 38.9, E-value 1.2e-08 413999016334 Pfam match to entry PF00557 Peptidase_M24,metallopeptidase M24, score 205.1, E-value 1.1e-58 413999016335 Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139 413999016336 putative FMN binding site [chemical binding]; other site 413999016337 Pfam match to entry PF00881 Nitroreductase,Nitroreductase, score 141.5, E-value 1.6e-39 413999016338 glycine radical enzyme, YjjI family; Region: glycyl_YjjI; TIGR04040 413999016339 Pyruvate formate lyase; Region: PFL; pfam02901 413999016340 glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041 413999016341 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 413999016342 PS01087 Radical activating enzymes signature. 413999016343 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 62.9, E-value 7.4e-16 413999016344 PS00190 Cytochrome c family heme-binding site signature. 413999016345 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 17.9, E-value 0.00038 413999016346 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 413999016347 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain, score 14.2, E-value 0.0015 413999016348 putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959 413999016349 [FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956 413999016350 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999016351 FeS/SAM binding site; other site 413999016352 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 69.8, E-value 6.2e-18 413999016353 thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613 413999016354 VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; Region: VHS_ENTH_ANTH; cl02544 413999016355 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999016356 FeS/SAM binding site; other site 413999016357 Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876 413999016358 Pfam match to entry PF05184 SapB_1, Saposin-like type B, region 1, score 11.6, E-value 0.0085 413999016359 Pfam match to entry PF04055 Radical_SAM, Radical SAM superfamily, score 48.0, E-value 2.2e-11 413999016360 [FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918 413999016361 E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880 413999016362 G1 box; other site 413999016363 GTP/Mg2+ binding site [chemical binding]; other site 413999016364 Switch I region; other site 413999016365 G2 box; other site 413999016366 Switch II region; other site 413999016367 G3 box; other site 413999016368 G4 box; other site 413999016369 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016370 Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322 413999016371 Na binding site [ion binding]; other site 413999016372 Pfam match to entry PF00474 SSF, Sodium:solute symporter family, score -72.3, E-value 1.9e-06 413999016373 10 probable transmembrane helices predicted for CBO3585 by TMHMM2.0 at aa 24-46, 74-96, 106-128, 135-152,167-189, 210-232, 261-283, 304-323, 333-355 and 376-398 413999016374 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 413999016375 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 413999016376 Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 78.7, E-value 1.3e-20 413999016377 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432 413999016378 DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481 413999016379 active site 413999016380 PHP-associated; Region: PHP_C; pfam13263 413999016381 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region, score 16.9, E-value 0.016 413999016382 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region, score 42.6, E-value 9.4e-10 413999016383 dUTPase; Region: dUTPase_2; pfam08761 413999016384 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527 413999016385 active site 413999016386 homodimer interface [polypeptide binding]; other site 413999016387 metal binding site [ion binding]; metal-binding site 413999016388 Protein of unknown function, DUF606; Region: DUF606; pfam04657 413999016389 Pfam match to entry PF04657 DUF606, Protein of unknown function, DUF606, score 119.2, E-value 8e-33 413999016390 5 probable transmembrane helices predicted for CBO3589 by TMHMM2.0 at aa 2-20, 35-57, 66-88, 92-114 and 121-139 413999016391 Transcriptional regulator [Transcription]; Region: LysR; COG0583 413999016392 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 413999016393 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 413999016394 dimerization interface [polypeptide binding]; other site 413999016395 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 86.2, E-value 6.7e-23 413999016396 PS00044 Bacterial regulatory proteins, lysR family signature. 413999016397 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain, score 103.9, E-value 3.2e-28 413999016398 Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404 413999016399 Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459 413999016400 active site 413999016401 catalytic residues [active] 413999016402 Pfam match to entry PF00082 Peptidase_S8, Subtilase, score 25.6, E-value 9e-11 413999016403 PS00136 Serine proteases, subtilase,aspartic acid active site. 413999016404 PS00137 Serine proteases, subtilase,histidine active site. 413999016405 putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837 413999016406 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 413999016407 C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420 413999016408 putative dimerization interface [polypeptide binding]; other site 413999016409 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain, score 172.6, E-value 6.7e-49 413999016410 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 88.0, E-value 2e-23 413999016411 PS00044 Bacterial regulatory proteins, lysR family signature. 413999016412 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 413999016413 Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155 413999016414 putative ligand binding site [chemical binding]; other site 413999016415 NAD binding site [chemical binding]; other site 413999016416 catalytic site [active] 413999016417 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain,score 166.7, E-value 4.2e-47 413999016418 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 413999016419 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain,score 28.9, E-value 1.8e-06 413999016420 acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724 413999016421 Pfam match to entry PF03255 ACCA, Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit, score 153.0, E-value 5.3e-43 413999016422 acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654 413999016423 Elongation factor 1 gamma, conserved domain; Region: EF1G; pfam00647 413999016424 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 413999016425 Pfam match to entry PF01039 Carboxyl_trans,Carboxyl transferase domain, score 53.2, E-value 9.6e-15 413999016426 biotin carboxylase; Validated; Region: PRK05586 413999016427 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 413999016428 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 413999016429 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 413999016430 Pfam match to entry PF02785 Biotin_carb_C, Biotin carboxylase C-terminal domain, score 216.3, E-value 4.6e-62 413999016431 Pfam match to entry PF02786 CPSase_L_D2,Carbamoyl-phosphate synthase L chain, ATP binding domain,score 384.4, E-value 1.2e-112 413999016432 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 413999016433 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 413999016434 Pfam match to entry PF00289 CPSase_L_chain,Carbamoyl-phosphate synthase L chain, N-terminal domain,score 166.5, E-value 4.6e-47 413999016435 FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288 413999016436 Pfam match to entry PF03061 4HBT, Thioesterase superfamily, score 74.3, E-value 2.7e-19 413999016437 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302 413999016438 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 413999016439 carboxyltransferase (CT) interaction site; other site 413999016440 biotinylation site [posttranslational modification]; other site 413999016441 Pfam match to entry PF00364 biotin_lipoyl,Biotin-requiring enzyme, score 105.4, E-value 1.2e-28 413999016442 beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150 413999016443 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 413999016444 dimer interface [polypeptide binding]; other site 413999016445 active site 413999016446 Pfam match to entry PF02801 ketoacyl-synt_C,Beta-ketoacyl synthase, C-terminal domain, score 239.2,E-value 5.9e-69 413999016447 Pfam match to entry PF00109 ketoacyl-synt,Beta-ketoacyl synthase, N-terminal domain, score 271.4,E-value 1.2e-78 413999016448 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 413999016449 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 413999016450 NAD(P) binding site [chemical binding]; other site 413999016451 homotetramer interface [polypeptide binding]; other site 413999016452 homodimer interface [polypeptide binding]; other site 413999016453 active site 413999016454 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 359.4, E-value 4.1e-105 413999016455 PS00061 Short-chain dehydrogenases/reductases family signature. 413999016456 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331 413999016457 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 413999016458 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain, score 166.4, E-value 4.8e-47 413999016459 putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151 413999016460 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 413999016461 FMN binding site [chemical binding]; other site 413999016462 substrate binding site [chemical binding]; other site 413999016463 putative catalytic residue [active] 413999016464 Pfam match to entry PF03060 NPD, 2-nitropropane dioxygenase, score 359.1, E-value 5e-105 413999016465 acyl carrier protein; Provisional; Region: acpP; PRK00982 413999016466 Pfam match to entry PF00550 pp-binding,Phosphopantetheine attachment site, score 58.7, E-value 1.3e-14 413999016467 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 413999016468 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 413999016469 dimer interface [polypeptide binding]; other site 413999016470 active site 413999016471 CoA binding pocket [chemical binding]; other site 413999016472 1 probable transmembrane helix predicted for CBO3604 by TMHMM2.0 at aa 306-325 413999016473 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 413999016474 MarR family; Region: MarR_2; pfam12802 413999016475 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 413999016476 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 413999016477 FMN binding site [chemical binding]; other site 413999016478 substrate binding site [chemical binding]; other site 413999016479 putative catalytic residue [active] 413999016480 Pfam match to entry PF03060 NPD, 2-nitropropane dioxygenase, score 208.8, E-value 8.4e-60 413999016481 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 413999016482 Peptidase family M23; Region: Peptidase_M23; pfam01551 413999016483 Pfam match to entry PF01551 Peptidase_M37,Peptidase M23/M37, score 148.0, E-value 1.7e-41 413999016484 Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935 413999016485 Replication initiation and membrane attachment; Region: DnaB_2; pfam07261 413999016486 Replication initiation and membrane attachment; Region: DnaB_2; cl12121 413999016487 Pfam match to entry PF04271 DnaD, DnaD-like domain,score 84.1, E-value 2.9e-22 413999016488 Pfam match to entry PF04271 DnaD, DnaD-like domain,score 88.1, E-value 1.9e-23 413999016489 DNA replication protein DnaC; Validated; Region: PRK06835 413999016490 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999016491 Walker A motif; other site 413999016492 ATP binding site [chemical binding]; other site 413999016493 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016494 PEP synthetase regulatory protein; Provisional; Region: PRK05339 413999016495 Pfam match to entry PF03618 DUF299, Domain of unknown function (DUF299), score 303.4, E-value 2.9e-88 413999016496 CoA binding domain; Region: CoA_binding_2; pfam13380 413999016497 flavoprotein, HI0933 family; Region: TIGR00275 413999016498 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 413999016499 PS00107 Protein kinases ATP-binding region signature. 413999016500 Pfam match to entry PF03486 HI0933_like,HI0933-like protein, score 463.6, E-value 1.7e-136 413999016501 Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643 413999016502 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 413999016503 active site 413999016504 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 413999016505 active site 413999016506 Pfam match to entry PF01643 Acyl-ACP_TE, Acyl-ACP thioesterase, score 29.5, E-value 4.8e-09 413999016507 hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980 413999016508 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 413999016509 Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788 413999016510 GDP-binding site [chemical binding]; other site 413999016511 ACT binding site; other site 413999016512 IMP binding site; other site 413999016513 Pfam match to entry PF00709 Adenylsucc_synt,Adenylosuccinate synthetase, score 844.9, E-value 2.8e-251 413999016514 PS00513 Adenylosuccinate synthetase active site. 413999016515 PS01266 Adenylosuccinate synthetase GTP-binding site. 413999016516 Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509 413999016517 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 413999016518 Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109 413999016519 This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799 413999016520 active site 413999016521 substrate binding site [chemical binding]; other site 413999016522 metal binding site [ion binding]; metal-binding site 413999016523 Pfam match to entry PF00408 PGM_PMM,Phosphoglucomutase/phosphomannomutase, C-terminal domain,score 7.8, E-value 0.002 413999016524 Pfam match to entry PF02880 PGM_PMM_III,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III, score 3.6, E-value 0.014 413999016525 Pfam match to entry PF02879 PGM_PMM_II,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II, score -11.3, E-value 0.012 413999016526 Pfam match to entry PF02878 PGM_PMM_I,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I, score 207.1, E-value 2.7e-59 413999016527 PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 413999016528 replicative DNA helicase; Provisional; Region: PRK05595 413999016529 DnaB-like helicase N terminal domain; Region: DnaB; pfam00772 413999016530 DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984 413999016531 Walker A motif; other site 413999016532 ATP binding site [chemical binding]; other site 413999016533 Walker B motif; other site 413999016534 DNA binding loops [nucleotide binding] 413999016535 Pfam match to entry PF03796 DnaB_C, DnaB-like helicase C terminal domain, score 442.2, E-value 4.6e-130 413999016536 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016537 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016538 Pfam match to entry PF00772 DnaB, DnaB-like helicase N terminal domain, score 136.1, E-value 6.6e-38 413999016539 ATP-dependent protease, Lon family; Region: spore_lon_C; TIGR02903 413999016540 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 413999016541 Walker A motif; other site 413999016542 ATP binding site [chemical binding]; other site 413999016543 Walker B motif; other site 413999016544 arginine finger; other site 413999016545 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 413999016546 Pfam match to entry PF05362 Lon_C, Lon protease (S16) C-terminal proteolytic domain, score 33.7, E-value 2.2e-17 413999016547 PS01046 ATP-dependent serine proteases, lon family,serine active site. 413999016548 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA), score 42.6, E-value 9.3e-10 413999016549 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016550 50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137 413999016551 Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281 413999016552 Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948 413999016553 Pfam match to entry PF03948 Ribosomal_L9_C,Ribosomal protein L9, C-terminal domain, score 92.4,E-value 9.4e-25 413999016554 Pfam match to entry PF01281 Ribosomal_L9_N,Ribosomal protein L9, N-terminal domain, score 84.8,E-value 1.8e-22 413999016555 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887 413999016556 DHH family; Region: DHH; pfam01368 413999016557 DHHA1 domain; Region: DHHA1; pfam02272 413999016558 Pfam match to entry PF02272 DHHA1, DHHA1 domain,score 51.7, E-value 1.7e-12 413999016559 Pfam match to entry PF01368 DHH, DHH family, score 94.2, E-value 2.8e-25 413999016560 3 probable transmembrane helices predicted for CBO3623 by TMHMM2.0 at aa 13-30, 34-51 and 163-180 413999016561 Predicted membrane protein (DUF2232); Region: DUF2232; pfam09991 413999016562 8 probable transmembrane helices predicted for CBO3624 by TMHMM2.0 at aa 20-42, 55-72, 76-95, 102-124,183-202, 225-244, 254-276 and 289-311 413999016563 MazG-like family; Region: MazG-like; pfam12643 413999016564 30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391 413999016565 Pfam match to entry PF01084 Ribosomal_S18,Ribosomal protein S18, score 110.7, E-value 2.9e-30 413999016566 PS00057 Ribosomal protein S18 signature. 413999016567 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 413999016568 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 413999016569 dimer interface [polypeptide binding]; other site 413999016570 ssDNA binding site [nucleotide binding]; other site 413999016571 tetramer (dimer of dimers) interface [polypeptide binding]; other site 413999016572 Pfam match to entry PF00436 SSB, Single-strand binding protein family, score 150.1, E-value 4.1e-42 413999016573 PS00735 Single-strand binding protein family signature 1. 413999016574 30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453 413999016575 Pfam match to entry PF01250 Ribosomal_S6, Ribosomal protein S6, score 120.9, E-value 2.5e-33 413999016576 benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263 413999016577 2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050 413999016578 Pfam match to entry PF06050 HGD-D,2-hydroxyglutaryl-CoA dehydratase, D-component, score 376.5, E-value 2.8e-110 413999016579 Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107 413999016580 Pfam match to entry PF06107 DUF951, Bacterial protein of unknown function (DUF951), score 143.4, E-value 4.1e-40 413999016581 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 413999016582 Mechanosensitive ion channel; Region: MS_channel; pfam00924 413999016583 Pfam match to entry PF00924 MS_channel,Mechanosensitive ion channel, score 157.4, E-value 2.6e-44 413999016584 2 probable transmembrane helices predicted for CBO3631 by TMHMM2.0 at aa 27-49 and 90-112 413999016585 Protein of unknown function (DUF3343); Region: DUF3343; pfam11823 413999016586 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 413999016587 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 413999016588 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 413999016589 catalytic residue [active] 413999016590 Pfam match to entry PF00266 aminotran_5,Aminotransferase class-V, score -2.9, E-value 6.7e-10 413999016591 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465 413999016592 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20, score 113.4, E-value 4.6e-31 413999016593 8 probable transmembrane helices predicted for CBO3634 by TMHMM2.0 at aa 12-45, 65-87, 152-174, 217-239,244-266, 271-293, 305-324 and 328-345 413999016594 Protein of unknown function (DUF1256); Region: DUF1256; cl06087 413999016595 1 probable transmembrane helix predicted for CBO3637 by TMHMM2.0 at aa 15-37 413999016596 ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180 413999016597 ParB-like nuclease domain; Region: ParB; smart00470 413999016598 Pfam match to entry PF02195 ParBc, ParB-like nuclease domain, score 105.4, E-value 1.2e-28 413999016599 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 413999016600 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 413999016601 P-loop; other site 413999016602 Magnesium ion binding site [ion binding]; other site 413999016603 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 413999016604 Magnesium ion binding site [ion binding]; other site 413999016605 Pfam match to entry PF00991 ParA, ParA family ATPase, score 136.7, E-value 4.4e-38 413999016606 nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285 413999016607 ParB-like nuclease domain; Region: ParBc; pfam02195 413999016608 Pfam match to entry PF02195 ParBc, ParB-like nuclease domain, score 119.6, E-value 6.3e-33 413999016609 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357 413999016610 16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107 413999016611 Pfam match to entry PF02527 GidB, Glucose inhibited division protein, score 230.6, E-value 2.3e-66 413999016612 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192 413999016613 tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335 413999016614 NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206 413999016615 GidA associated domain 3; Region: GIDA_assoc_3; pfam13932 413999016616 Pfam match to entry PF01134 GIDA, Glucose inhibited division protein A, score 726.0, E-value 1.8e-215 413999016617 PS01281 Glucose inhibited division protein A family signature 2. 413999016618 PS01280 Glucose inhibited division protein A family signature 1. 413999016619 tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291 413999016620 GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396 413999016621 trmE is a tRNA modification GTPase; Region: trmE; cd04164 413999016622 G1 box; other site 413999016623 GTP/Mg2+ binding site [chemical binding]; other site 413999016624 Switch I region; other site 413999016625 G2 box; other site 413999016626 Switch II region; other site 413999016627 G3 box; other site 413999016628 G4 box; other site 413999016629 G5 box; other site 413999016630 Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631 413999016631 Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function, score 12.5, E-value 8.3e-08 413999016632 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016633 Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847 413999016634 jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation. The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414 413999016635 G-X-X-G motif; other site 413999016636 R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644 413999016637 RxxxH motif; other site 413999016638 Pfam match to entry PF01424 R3H, R3H domain, score 61.0, E-value 2.7e-15 413999016639 putative inner membrane protein translocase component YidC; Provisional; Region: PRK00145 413999016640 Pfam match to entry PF02096 60KD_IMP, 60Kd inner membrane protein, score 263.1, E-value 3.9e-76 413999016641 4 probable transmembrane helices predicted for CBO3645 by TMHMM2.0 at aa 28-50, 103-125, 138-157 and 172-194 413999016642 Haemolytic domain; Region: Haemolytic; pfam01809 413999016643 Pfam match to entry PF01809 DUF37, Domain of unknown function DUF37, score 147.2, E-value 3e-41 413999016644 ribonuclease P; Reviewed; Region: rnpA; PRK00499 413999016645 Pfam match to entry PF00825 Ribonuclease_P,Ribonuclease P, score 90.7, E-value 3.1e-24 413999016646 50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399 413999016647 Pfam match to entry PF00468 Ribosomal_L34,Ribosomal protein L34, score 57.8, E-value 2.4e-14 413999016648 DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826 413999016649 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113 413999016650 active site 413999016651 PHP Thumb interface [polypeptide binding]; other site 413999016652 metal binding site [ion binding]; metal-binding site 413999016653 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 413999016654 generic binding surface II; other site 413999016655 generic binding surface I; other site 413999016656 superfamily hit to SSF50249, Nucleic acid-binding proteins, score 1.5e-10 413999016657 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 4.4e-14 413999016658 HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 1.2e-269 413999016659 superfamily hit to SSF89550, PHP domain, score 3.4e-59 413999016660 HMMPfam hit to PF02811, PHP domain C-terminal region, score 3.2e-33 413999016661 HMMPfam hit to PF02231, PHP domain N-terminal region, score 3.3e-32 413999016662 BlastProDom hit to PD008230, Q9ZAN0_STAAU_Q9ZAN0;,score 0.0009 413999016663 INT_SG3, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 3, catalytic domain. The CD contains various predicted bacterial and phage integrase/recombinase sequences for which not much experimental characterization is available; Region: INT_SG3_C; cd01186 413999016664 Int/Topo IB signature motif; other site 413999016665 superfamily hit to SSF56349, DNA breaking-rejoining enzymes, score 6.1e-34 413999016666 HMMPfam hit to PF00589, Phage integrase family,score 2e-15 413999016667 superfamily hit to SSF47954, Cyclin-like, score 0.0053 413999016668 Predicted helix-turn-helix motif with score 1388.000, SD 3.91 at aa 42-63, sequence STLRDIASNLNIARSTLRDRFK 413999016669 HMMPfam hit to PF05713, Bacterial mobilisation protein (MobC), score 0.00019 413999016670 Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432 413999016671 HMMPfam hit to PF03432, Relaxase/Mobilisation nuclease domain, score 8.3e-39 413999016672 1 probable transmembrane helix predicted for CBOP13 by TMHMM2.0 at aa 58-80 413999016673 Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126 413999016674 putative heme d1 biosynthesis radical SAM protein NirJ2; Region: rSAM_NirJ2; TIGR04055 413999016675 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 413999016676 FeS/SAM binding site; other site 413999016677 PS00442 Glutamine amidotransferases class-I active site.; ScanRegExp hit to PS00442, GATASE_TYPE_I, score NA 413999016678 HMMPfam hit to PF04055, Radical SAM superfamily,score 1.4e-23 413999016679 1 probable transmembrane helix predicted for btcB by TMHMM2.0 at aa 13-35 413999016680 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 413999016681 Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312 413999016682 Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312 413999016683 superfamily hit to SSF75001, Dipeptidyl peptidase I (cathepsin C), exclusion domain, score 0.015 413999016684 ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204 413999016685 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 413999016686 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 413999016687 Walker A/P-loop; other site 413999016688 ATP binding site [chemical binding]; other site 413999016689 Q-loop/lid; other site 413999016690 ABC transporter signature motif; other site 413999016691 Walker B; other site 413999016692 D-loop; other site 413999016693 H-loop/switch region; other site 413999016694 superfamily hit to SSF90123, Multidrug resistance ABC transporter MsbA, N-terminal domain, score 3.6e-61 413999016695 5 probable transmembrane helices predicted for CBOP19 by TMHMM2.0 at aa 20-42, 62-84, 129-151, 161-183 and 243-265 413999016696 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.5e-17 413999016697 superfamily hit to SSF52540, P-loop containing nucleoside triphosphate hydrolases, score 1e-49 413999016698 HMMPfam hit to PF00005, ABC transporter, score 3.7e-45 413999016699 PS00017 ATP/GTP-binding site motif A (P-loop). 413999016700 BlastProDom hit to PD000006, Q97IT2_CLOAB_Q97IT2;,score 7e-11