-- dump date   	20140619_043957
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
720554000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
720554000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
720554000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000004	Walker A motif; other site
720554000005	ATP binding site [chemical binding]; other site
720554000006	Walker B motif; other site
720554000007	arginine finger; other site
720554000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
720554000009	DnaA box-binding interface [nucleotide binding]; other site
720554000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
720554000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
720554000012	putative DNA binding surface [nucleotide binding]; other site
720554000013	dimer interface [polypeptide binding]; other site
720554000014	beta-clamp/clamp loader binding surface; other site
720554000015	beta-clamp/translesion DNA polymerase binding surface; other site
720554000016	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554000017	RNA binding surface [nucleotide binding]; other site
720554000018	recombination protein F; Reviewed; Region: recF; PRK00064
720554000019	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
720554000020	Walker A/P-loop; other site
720554000021	ATP binding site [chemical binding]; other site
720554000022	Q-loop/lid; other site
720554000023	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554000024	ABC transporter signature motif; other site
720554000025	Walker B; other site
720554000026	D-loop; other site
720554000027	H-loop/switch region; other site
720554000028	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
720554000029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554000030	ATP binding site [chemical binding]; other site
720554000031	Mg2+ binding site [ion binding]; other site
720554000032	G-X-G motif; other site
720554000033	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
720554000034	anchoring element; other site
720554000035	dimer interface [polypeptide binding]; other site
720554000036	ATP binding site [chemical binding]; other site
720554000037	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
720554000038	active site
720554000039	putative metal-binding site [ion binding]; other site
720554000040	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
720554000041	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
720554000042	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
720554000043	P-loop; other site
720554000044	Magnesium ion binding site [ion binding]; other site
720554000045	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
720554000046	ParB-like nuclease domain; Region: ParB; smart00470
720554000047	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
720554000048	binding surface
720554000049	TPR motif; other site
720554000050	TPR repeat; Region: TPR_11; pfam13414
720554000051	seryl-tRNA synthetase; Provisional; Region: PRK05431
720554000052	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
720554000053	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
720554000054	dimer interface [polypeptide binding]; other site
720554000055	active site
720554000056	motif 1; other site
720554000057	motif 2; other site
720554000058	motif 3; other site
720554000059	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
720554000060	putative substrate translocation pore; other site
720554000061	Major Facilitator Superfamily; Region: MFS_1; pfam07690
720554000062	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
720554000063	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554000064	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
720554000065	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
720554000066	active site
720554000067	dimer interface [polypeptide binding]; other site
720554000068	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
720554000069	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
720554000070	active site
720554000071	FMN binding site [chemical binding]; other site
720554000072	substrate binding site [chemical binding]; other site
720554000073	3Fe-4S cluster binding site [ion binding]; other site
720554000074	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
720554000075	domain interface; other site
720554000076	S-layer homology domain; Region: SLH; pfam00395
720554000077	S-layer homology domain; Region: SLH; pfam00395
720554000078	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
720554000079	VanW like protein; Region: VanW; pfam04294
720554000080	G5 domain; Region: G5; pfam07501
720554000081	SigmaK-factor processing regulatory protein BofA; Region: BofA; cl06466
720554000082	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
720554000083	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
720554000084	dimer interface [polypeptide binding]; other site
720554000085	PYR/PP interface [polypeptide binding]; other site
720554000086	TPP binding site [chemical binding]; other site
720554000087	substrate binding site [chemical binding]; other site
720554000088	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554000089	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
720554000090	Domain of unknown function; Region: EKR; pfam10371
720554000091	4Fe-4S binding domain; Region: Fer4_6; pfam12837
720554000092	4Fe-4S binding domain; Region: Fer4; pfam00037
720554000093	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
720554000094	TPP-binding site [chemical binding]; other site
720554000095	dimer interface [polypeptide binding]; other site
720554000096	cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223
720554000097	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
720554000098	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554000099	non-specific DNA binding site [nucleotide binding]; other site
720554000100	salt bridge; other site
720554000101	sequence-specific DNA binding site [nucleotide binding]; other site
720554000102	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
720554000103	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
720554000104	active site
720554000105	ATP binding site [chemical binding]; other site
720554000106	substrate binding site [chemical binding]; other site
720554000107	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
720554000108	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
720554000109	Potassium binding sites [ion binding]; other site
720554000110	Cesium cation binding sites [ion binding]; other site
720554000111	YabG peptidase U57; Region: Peptidase_U57; pfam05582
720554000112	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
720554000113	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
720554000114	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
720554000115	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
720554000116	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
720554000117	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554000118	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
720554000119	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
720554000120	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
720554000121	Transcriptional regulators [Transcription]; Region: FadR; COG2186
720554000122	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
720554000123	DNA-binding site [nucleotide binding]; DNA binding site
720554000124	FCD domain; Region: FCD; pfam07729
720554000125	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554000126	metal-binding site [ion binding]
720554000127	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
720554000128	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554000129	active site
720554000130	phosphorylation site [posttranslational modification]
720554000131	intermolecular recognition site; other site
720554000132	dimerization interface [polypeptide binding]; other site
720554000133	CheB methylesterase; Region: CheB_methylest; pfam01339
720554000134	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000135	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554000136	Walker A motif; other site
720554000137	ATP binding site [chemical binding]; other site
720554000138	Walker B motif; other site
720554000139	arginine finger; other site
720554000140	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
720554000141	Protein of unknown function (DUF342); Region: DUF342; pfam03961
720554000142	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
720554000143	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
720554000144	active site
720554000145	metal binding site [ion binding]; metal-binding site
720554000146	DNA binding site [nucleotide binding]
720554000147	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554000148	AAA domain; Region: AAA_23; pfam13476
720554000149	Walker A/P-loop; other site
720554000150	ATP binding site [chemical binding]; other site
720554000151	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
720554000152	NlpC/P60 family; Region: NLPC_P60; pfam00877
720554000153	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
720554000154	Oxygen tolerance; Region: BatD; pfam13584
720554000155	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554000156	TPR motif; other site
720554000157	TPR repeat; Region: TPR_11; pfam13414
720554000158	binding surface
720554000159	von Willebrand factor type A domain; Region: VWA_2; pfam13519
720554000160	metal ion-dependent adhesion site (MIDAS); other site
720554000161	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
720554000162	metal ion-dependent adhesion site (MIDAS); other site
720554000163	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
720554000164	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554000165	metal ion-dependent adhesion site (MIDAS); other site
720554000166	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554000167	ATPase family associated with various cellular activities (AAA); Region: AAA_3; pfam07726
720554000168	ATP binding site [chemical binding]; other site
720554000169	Walker A motif; other site
720554000170	Walker B motif; other site
720554000171	arginine finger; other site
720554000172	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
720554000173	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
720554000174	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
720554000175	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
720554000176	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554000177	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
720554000178	germination protein YpeB; Region: spore_YpeB; TIGR02889
720554000179	CAAX protease self-immunity; Region: Abi; pfam02517
720554000180	DNA replication protein DnaC; Validated; Region: PRK06835
720554000181	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000182	Walker A motif; other site
720554000183	ATP binding site [chemical binding]; other site
720554000184	Walker B motif; other site
720554000185	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
720554000186	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
720554000187	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
720554000188	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
720554000189	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
720554000190	flagellar motor protein MotP; Reviewed; Region: PRK06743
720554000191	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
720554000192	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
720554000193	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
720554000194	ligand binding site [chemical binding]; other site
720554000195	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
720554000196	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
720554000197	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554000198	S-adenosylmethionine binding site [chemical binding]; other site
720554000199	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
720554000200	Domain of unknown function DUF20; Region: UPF0118; pfam01594
720554000201	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
720554000202	SLBB domain; Region: SLBB; pfam10531
720554000203	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554000204	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
720554000205	FMN-binding domain; Region: FMN_bind; cl01081
720554000206	electron transport complex RsxE subunit; Provisional; Region: PRK12405
720554000207	electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943
720554000208	Predicted NADH:ubiquinone oxidoreductase, subunit RnfB [Energy production and conversion]; Region: COG2878
720554000209	Putative Fe-S cluster; Region: FeS; cl17515
720554000210	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
720554000211	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
720554000212	shikimate kinase; Reviewed; Region: aroK; PRK00131
720554000213	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
720554000214	ADP binding site [chemical binding]; other site
720554000215	magnesium binding site [ion binding]; other site
720554000216	putative shikimate binding site; other site
720554000217	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
720554000218	substrate binding site [chemical binding]; other site
720554000219	active site
720554000220	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
720554000221	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
720554000222	oligoendopeptidase F; Region: pepF; TIGR00181
720554000223	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
720554000224	active site
720554000225	Zn binding site [ion binding]; other site
720554000226	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
720554000227	homodimer interface [polypeptide binding]; other site
720554000228	chemical substrate binding site [chemical binding]; other site
720554000229	oligomer interface [polypeptide binding]; other site
720554000230	metal binding site [ion binding]; metal-binding site
720554000231	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000232	Interdomain contacts; other site
720554000233	Cytokine receptor motif; other site
720554000234	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000235	Interdomain contacts; other site
720554000236	Cytokine receptor motif; other site
720554000237	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000238	Interdomain contacts; other site
720554000239	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000240	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000241	Interdomain contacts; other site
720554000242	Cytokine receptor motif; other site
720554000243	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000244	Interdomain contacts; other site
720554000245	Cytokine receptor motif; other site
720554000246	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000247	Interdomain contacts; other site
720554000248	Cytokine receptor motif; other site
720554000249	S-layer homology domain; Region: SLH; pfam00395
720554000250	S-layer homology domain; Region: SLH; pfam00395
720554000251	putative oxidoreductase; Provisional; Region: PRK12831
720554000252	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554000253	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
720554000254	ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222
720554000255	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
720554000256	FAD binding pocket [chemical binding]; other site
720554000257	FAD binding motif [chemical binding]; other site
720554000258	phosphate binding motif [ion binding]; other site
720554000259	beta-alpha-beta structure motif; other site
720554000260	NAD binding pocket [chemical binding]; other site
720554000261	Iron coordination center [ion binding]; other site
720554000262	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554000263	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
720554000264	active site
720554000265	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
720554000266	glutamate dehydrogenase; Provisional; Region: PRK09414
720554000267	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
720554000268	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
720554000269	NAD(P) binding site [chemical binding]; other site
720554000270	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
720554000271	nucleoside/Zn binding site; other site
720554000272	dimer interface [polypeptide binding]; other site
720554000273	catalytic motif [active]
720554000274	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
720554000275	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
720554000276	Glycosyl hydrolase family 43; Region: GH43_4; cd08983
720554000277	active site
720554000278	Alpha-L-arabinofuranosidase B (ABFB); Region: AbfB; pfam05270
720554000279	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000280	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000281	P-loop Domain of unknown function (DUF2791); Region: DUF2791; pfam10923
720554000282	AAA ATPase domain; Region: AAA_16; pfam13191
720554000283	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
720554000284	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
720554000285	V-type ATP synthase subunit D; Reviewed; Region: PRK00373
720554000286	V-type ATP synthase subunit B; Provisional; Region: PRK04196
720554000287	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
720554000288	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
720554000289	Walker A motif homologous position; other site
720554000290	Walker B motif; other site
720554000291	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
720554000292	V-type ATP synthase subunit A; Provisional; Region: PRK04192
720554000293	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
720554000294	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
720554000295	Walker A motif/ATP binding site; other site
720554000296	Walker B motif; other site
720554000297	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
720554000298	V-type ATP synthase subunit F; Provisional; Region: PRK01395
720554000299	V-type ATP synthase subunit C; Provisional; Region: PRK01198
720554000300	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
720554000301	V-type ATP synthase subunit E; Provisional; Region: PRK03963; cl17074
720554000302	ATP synthase (E/31 kDa) subunit; Region: vATP-synt_E; pfam01991
720554000303	ATP synthase subunit C; Region: ATP-synt_C; cl00466
720554000304	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
720554000305	V-type ATP synthase subunit I; Validated; Region: PRK05771
720554000306	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
720554000307	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
720554000308	putative catalytic cysteine [active]
720554000309	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
720554000310	putative active site [active]
720554000311	metal binding site [ion binding]; metal-binding site
720554000312	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
720554000313	Domain of unknown function DUF20; Region: UPF0118; pfam01594
720554000314	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
720554000315	Prephenate dehydratase; Region: PDT; pfam00800
720554000316	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
720554000317	putative L-Phe binding site [chemical binding]; other site
720554000318	MazG-like family; Region: MazG-like; pfam12643
720554000319	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
720554000320	DHH family; Region: DHH; pfam01368
720554000321	DHHA1 domain; Region: DHHA1; pfam02272
720554000322	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
720554000323	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
720554000324	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
720554000325	replicative DNA helicase; Region: DnaB; TIGR00665
720554000326	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
720554000327	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
720554000328	Walker A motif; other site
720554000329	ATP binding site [chemical binding]; other site
720554000330	Walker B motif; other site
720554000331	DNA binding loops [nucleotide binding]
720554000332	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
720554000333	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
720554000334	Ligand Binding Site [chemical binding]; other site
720554000335	TilS substrate C-terminal domain; Region: TilS_C; smart00977
720554000336	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554000337	active site
720554000338	FtsH Extracellular; Region: FtsH_ext; pfam06480
720554000339	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
720554000340	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000341	Walker A motif; other site
720554000342	ATP binding site [chemical binding]; other site
720554000343	Walker B motif; other site
720554000344	arginine finger; other site
720554000345	Peptidase family M41; Region: Peptidase_M41; pfam01434
720554000346	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
720554000347	PHB binding site; other site
720554000348	CoenzymeA binding site [chemical binding]; other site
720554000349	subunit interaction site [polypeptide binding]; other site
720554000350	S-adenosylmethionine synthetase; Validated; Region: PRK05250
720554000351	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
720554000352	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
720554000353	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
720554000354	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
720554000355	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
720554000356	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
720554000357	active site
720554000358	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
720554000359	AAA domain; Region: AAA_30; pfam13604
720554000360	Family description; Region: UvrD_C_2; pfam13538
720554000361	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
720554000362	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000363	Walker A motif; other site
720554000364	ATP binding site [chemical binding]; other site
720554000365	Walker B motif; other site
720554000366	arginine finger; other site
720554000367	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
720554000368	hypothetical protein; Validated; Region: PRK00153
720554000369	recombination protein RecR; Reviewed; Region: recR; PRK00076
720554000370	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
720554000371	RecR protein; Region: RecR; pfam02132
720554000372	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
720554000373	putative active site [active]
720554000374	putative metal-binding site [ion binding]; other site
720554000375	tetramer interface [polypeptide binding]; other site
720554000376	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
720554000377	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554000378	Methyltransferase domain; Region: Methyltransf_31; pfam13847
720554000379	S-adenosylmethionine binding site [chemical binding]; other site
720554000380	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
720554000381	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554000382	Coenzyme A binding pocket [chemical binding]; other site
720554000383	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
720554000384	Domain of unknown function (DUF4037); Region: DUF4037; pfam13228
720554000385	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554000386	LysE type translocator; Region: LysE; pfam01810
720554000387	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554000388	S-adenosylmethionine binding site [chemical binding]; other site
720554000389	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
720554000390	active site
720554000391	NTP binding site [chemical binding]; other site
720554000392	metal binding triad [ion binding]; metal-binding site
720554000393	antibiotic binding site [chemical binding]; other site
720554000394	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
720554000395	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
720554000396	active site
720554000397	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554000398	dimerization interface [polypeptide binding]; other site
720554000399	putative DNA binding site [nucleotide binding]; other site
720554000400	putative Zn2+ binding site [ion binding]; other site
720554000401	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
720554000402	Sodium Bile acid symporter family; Region: SBF; cl17470
720554000403	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
720554000404	Low molecular weight phosphatase family; Region: LMWPc; cd00115
720554000405	active site
720554000406	Predicted permeases [General function prediction only]; Region: COG0701
720554000407	Predicted permease; Region: DUF318; cl17795
720554000408	Ferredoxin [Energy production and conversion]; Region: COG1146
720554000409	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
720554000410	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
720554000411	Domain of unknown function (DUF2703); Region: DUF2703; pfam10865
720554000412	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
720554000413	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
720554000414	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
720554000415	MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149
720554000416	This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110
720554000417	P loop nucleotide binding; other site
720554000418	switch II; other site
720554000419	This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110
720554000420	P loop nucleotide binding; other site
720554000421	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
720554000422	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
720554000423	switch II; other site
720554000424	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
720554000425	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
720554000426	metal binding site 2 [ion binding]; metal-binding site
720554000427	putative DNA binding helix; other site
720554000428	metal binding site 1 [ion binding]; metal-binding site
720554000429	dimer interface [polypeptide binding]; other site
720554000430	structural Zn2+ binding site [ion binding]; other site
720554000431	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554000432	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554000433	DNA binding residues [nucleotide binding]
720554000434	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
720554000435	putative active site [active]
720554000436	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
720554000437	four helix bundle protein; Region: TIGR02436
720554000438	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
720554000439	Mg binding site [ion binding]; other site
720554000440	nucleotide binding site [chemical binding]; other site
720554000441	putative protofilament interface [polypeptide binding]; other site
720554000442	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554000443	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554000444	DNA binding residues [nucleotide binding]
720554000445	DNA primase (bacterial type) [DNA replication, recombination, and repair]; Region: DnaG; COG0358
720554000446	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
720554000447	active site
720554000448	metal binding site [ion binding]; metal-binding site
720554000449	interdomain interaction site; other site
720554000450	Stage V sporulation protein S (SpoVS); Region: SpoVS; cl01005
720554000451	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554000452	non-specific DNA binding site [nucleotide binding]; other site
720554000453	salt bridge; other site
720554000454	sequence-specific DNA binding site [nucleotide binding]; other site
720554000455	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554000456	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554000457	metal binding site [ion binding]; metal-binding site
720554000458	active site
720554000459	I-site; other site
720554000460	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
720554000461	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554000462	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
720554000463	putative active site [active]
720554000464	putative NTP binding site [chemical binding]; other site
720554000465	putative nucleic acid binding site [nucleotide binding]; other site
720554000466	DNA-sulfur modification-associated; Region: DndB; pfam14072
720554000467	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
720554000468	active site
720554000469	Radical SAM superfamily; Region: Radical_SAM; pfam04055
720554000470	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554000471	FeS/SAM binding site; other site
720554000472	HsdM N-terminal domain; Region: HsdM_N; pfam12161
720554000473	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
720554000474	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554000475	S-adenosylmethionine binding site [chemical binding]; other site
720554000476	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554000477	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
720554000478	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554000479	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
720554000480	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
720554000481	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554000482	ATP binding site [chemical binding]; other site
720554000483	putative Mg++ binding site [ion binding]; other site
720554000484	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
720554000485	DEAD-like helicases superfamily; Region: DEXDc; smart00487
720554000486	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554000487	ATP binding site [chemical binding]; other site
720554000488	putative Mg++ binding site [ion binding]; other site
720554000489	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
720554000490	nucleotide binding region [chemical binding]; other site
720554000491	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
720554000492	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
720554000493	active site
720554000494	DNA binding site [nucleotide binding]
720554000495	Int/Topo IB signature motif; other site
720554000496	CHC2 zinc finger; Region: zf-CHC2; cl17510
720554000497	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
720554000498	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
720554000499	Integrase core domain; Region: rve; pfam00665
720554000500	AAA domain; Region: AAA_22; pfam13401
720554000501	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000502	Walker A motif; other site
720554000503	ATP binding site [chemical binding]; other site
720554000504	Bacterial TniB protein; Region: TniB; pfam05621
720554000505	Walker B motif; other site
720554000506	TniQ; Region: TniQ; pfam06527
720554000507	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
720554000508	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
720554000509	ligand binding site [chemical binding]; other site
720554000510	flexible hinge region; other site
720554000511	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
720554000512	non-specific DNA interactions [nucleotide binding]; other site
720554000513	DNA binding site [nucleotide binding]
720554000514	sequence specific DNA binding site [nucleotide binding]; other site
720554000515	putative cAMP binding site [chemical binding]; other site
720554000516	Cupin domain; Region: Cupin_2; cl17218
720554000517	Predicted permease; Region: DUF318; cl17795
720554000518	Predicted permease; Region: DUF318; cl17795
720554000519	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
720554000520	LysE type translocator; Region: LysE; cl00565
720554000521	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554000522	Zn2+ binding site [ion binding]; other site
720554000523	Mg2+ binding site [ion binding]; other site
720554000524	Uncharacterized conserved protein [Function unknown]; Region: COG3339
720554000525	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
720554000526	Low molecular weight phosphatase family; Region: LMWPc; cd00115
720554000527	active site
720554000528	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554000529	dimerization interface [polypeptide binding]; other site
720554000530	putative DNA binding site [nucleotide binding]; other site
720554000531	putative Zn2+ binding site [ion binding]; other site
720554000532	Predicted permeases [General function prediction only]; Region: COG0701
720554000533	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
720554000534	Domain of unknown function (DUF2703); Region: DUF2703; pfam10865
720554000535	Divergent AAA domain; Region: AAA_4; pfam04326
720554000536	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554000537	S-adenosylmethionine binding site [chemical binding]; other site
720554000538	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
720554000539	active site
720554000540	NTP binding site [chemical binding]; other site
720554000541	metal binding triad [ion binding]; metal-binding site
720554000542	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
720554000543	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
720554000544	active site
720554000545	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
720554000546	putative active site [active]
720554000547	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
720554000548	four helix bundle protein; Region: TIGR02436
720554000549	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
720554000550	Mg binding site [ion binding]; other site
720554000551	nucleotide binding site [chemical binding]; other site
720554000552	putative protofilament interface [polypeptide binding]; other site
720554000553	DNA primase, catalytic core; Region: dnaG; TIGR01391
720554000554	CHC2 zinc finger; Region: zf-CHC2; cl17510
720554000555	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
720554000556	active site
720554000557	metal binding site [ion binding]; metal-binding site
720554000558	interdomain interaction site; other site
720554000559	Protein of unknown function (DUF1009); Region: DUF1009; cl09182
720554000560	Stage V sporulation protein S (SpoVS); Region: SpoVS; cl01005
720554000561	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554000562	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554000563	metal binding site [ion binding]; metal-binding site
720554000564	active site
720554000565	I-site; other site
720554000566	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
720554000567	DNA-sulfur modification-associated; Region: DndB; pfam14072
720554000568	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
720554000569	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
720554000570	adenylosuccinate synthase; Region: purA; TIGR00184
720554000571	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554000572	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
720554000573	TIGR02687 family protein; Region: TIGR02687
720554000574	PglZ domain; Region: PglZ; pfam08665
720554000575	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
720554000576	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
720554000577	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
720554000578	Predicted nuclease of the RecB family [DNA replication, recombination, and repair]; Region: COG1637
720554000579	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
720554000580	Protein of unknown function (DUF1444); Region: DUF1444; cl02011
720554000581	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554000582	non-specific DNA binding site [nucleotide binding]; other site
720554000583	salt bridge; other site
720554000584	sequence-specific DNA binding site [nucleotide binding]; other site
720554000585	Domain of unknown function (DUF955); Region: DUF955; pfam06114
720554000586	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
720554000587	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
720554000588	active site
720554000589	DNA binding site [nucleotide binding]
720554000590	Int/Topo IB signature motif; other site
720554000591	DEAD-like helicases superfamily; Region: DEXDc; smart00487
720554000592	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554000593	ATP binding site [chemical binding]; other site
720554000594	putative Mg++ binding site [ion binding]; other site
720554000595	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554000596	nucleotide binding region [chemical binding]; other site
720554000597	ATP-binding site [chemical binding]; other site
720554000598	The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p; Region: HIRAN; smart00910
720554000599	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
720554000600	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
720554000601	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
720554000602	Integrase core domain; Region: rve; pfam00665
720554000603	AAA domain; Region: AAA_22; pfam13401
720554000604	TniQ; Region: TniQ; pfam06527
720554000605	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
720554000606	Divergent AAA domain; Region: AAA_4; pfam04326
720554000607	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
720554000608	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
720554000609	putative DNA binding site [nucleotide binding]; other site
720554000610	putative Zn2+ binding site [ion binding]; other site
720554000611	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554000612	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554000613	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554000614	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
720554000615	DOMON-like type 9 carbohydrate binding module of xylanases; Region: CBM9_like_1; cd00005
720554000616	Ca binding site [ion binding]; other site
720554000617	carbohydrate binding site [chemical binding]; other site
720554000618	S-layer homology domain; Region: SLH; pfam00395
720554000619	S-layer homology domain; Region: SLH; pfam00395
720554000620	S-layer homology domain; Region: SLH; pfam00395
720554000621	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
720554000622	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
720554000623	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
720554000624	peptide chain release factor 1; Validated; Region: prfA; PRK00591
720554000625	This domain is found in peptide chain release factors; Region: PCRF; smart00937
720554000626	RF-1 domain; Region: RF-1; pfam00472
720554000627	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
720554000628	ZIP Zinc transporter; Region: Zip; pfam02535
720554000629	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
720554000630	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
720554000631	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
720554000632	Low molecular weight phosphatase family; Region: LMWPc; cd00115
720554000633	active site
720554000634	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
720554000635	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554000636	active site
720554000637	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
720554000638	catalytic motif [active]
720554000639	Zn binding site [ion binding]; other site
720554000640	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
720554000641	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
720554000642	Mg++ binding site [ion binding]; other site
720554000643	putative catalytic motif [active]
720554000644	substrate binding site [chemical binding]; other site
720554000645	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
720554000646	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
720554000647	active site
720554000648	homodimer interface [polypeptide binding]; other site
720554000649	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
720554000650	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
720554000651	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
720554000652	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
720554000653	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
720554000654	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
720554000655	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
720554000656	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
720554000657	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
720554000658	beta subunit interaction interface [polypeptide binding]; other site
720554000659	Walker A motif; other site
720554000660	ATP binding site [chemical binding]; other site
720554000661	Walker B motif; other site
720554000662	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
720554000663	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
720554000664	core domain interface [polypeptide binding]; other site
720554000665	delta subunit interface [polypeptide binding]; other site
720554000666	epsilon subunit interface [polypeptide binding]; other site
720554000667	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
720554000668	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
720554000669	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
720554000670	alpha subunit interaction interface [polypeptide binding]; other site
720554000671	Walker A motif; other site
720554000672	ATP binding site [chemical binding]; other site
720554000673	Walker B motif; other site
720554000674	inhibitor binding site; inhibition site
720554000675	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
720554000676	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
720554000677	gamma subunit interface [polypeptide binding]; other site
720554000678	epsilon subunit interface [polypeptide binding]; other site
720554000679	LBP interface [polypeptide binding]; other site
720554000680	Fibronectin type 3 domain; Region: FN3; smart00060
720554000681	S-layer homology domain; Region: SLH; pfam00395
720554000682	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000683	Interdomain contacts; other site
720554000684	Cytokine receptor motif; other site
720554000685	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000686	Interdomain contacts; other site
720554000687	Cytokine receptor motif; other site
720554000688	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554000689	Interdomain contacts; other site
720554000690	Cytokine receptor motif; other site
720554000691	S-layer homology domain; Region: SLH; pfam00395
720554000692	S-layer homology domain; Region: SLH; pfam00395
720554000693	Protein of unknown function (DUF1779); Region: DUF1779; pfam08680
720554000694	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
720554000695	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
720554000696	hinge; other site
720554000697	active site
720554000698	Stage II sporulation protein; Region: SpoIID; pfam08486
720554000699	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
720554000700	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
720554000701	Peptidase family M23; Region: Peptidase_M23; pfam01551
720554000702	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554000703	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554000704	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554000705	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554000706	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000707	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000708	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
720554000709	NlpC/P60 family; Region: NLPC_P60; cl17555
720554000710	Stage III sporulation protein D; Region: SpoIIID; pfam12116
720554000711	rod shape-determining protein Mbl; Provisional; Region: PRK13928
720554000712	MreB and similar proteins; Region: MreB_like; cd10225
720554000713	nucleotide binding site [chemical binding]; other site
720554000714	Mg binding site [ion binding]; other site
720554000715	putative protofilament interaction site [polypeptide binding]; other site
720554000716	RodZ interaction site [polypeptide binding]; other site
720554000717	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
720554000718	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
720554000719	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
720554000720	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
720554000721	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
720554000722	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
720554000723	Rod binding protein; Region: Rod-binding; pfam10135
720554000724	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
720554000725	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
720554000726	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
720554000727	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554000728	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
720554000729	pur operon repressor; Provisional; Region: PRK09213
720554000730	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
720554000731	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554000732	active site
720554000733	regulatory protein SpoVG; Reviewed; Region: PRK13259
720554000734	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
720554000735	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
720554000736	Substrate binding site; other site
720554000737	Mg++ binding site; other site
720554000738	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
720554000739	active site
720554000740	substrate binding site [chemical binding]; other site
720554000741	CoA binding site [chemical binding]; other site
720554000742	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
720554000743	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
720554000744	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554000745	active site
720554000746	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
720554000747	putative active site [active]
720554000748	catalytic residue [active]
720554000749	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
720554000750	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
720554000751	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554000752	ATP binding site [chemical binding]; other site
720554000753	putative Mg++ binding site [ion binding]; other site
720554000754	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554000755	nucleotide binding region [chemical binding]; other site
720554000756	ATP-binding site [chemical binding]; other site
720554000757	TRCF domain; Region: TRCF; pfam03461
720554000758	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
720554000759	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
720554000760	stage V sporulation protein T; Region: spore_V_T; TIGR02851
720554000761	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
720554000762	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
720554000763	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
720554000764	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
720554000765	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
720554000766	homodimer interface [polypeptide binding]; other site
720554000767	metal binding site [ion binding]; metal-binding site
720554000768	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
720554000769	homodimer interface [polypeptide binding]; other site
720554000770	active site
720554000771	putative chemical substrate binding site [chemical binding]; other site
720554000772	metal binding site [ion binding]; metal-binding site
720554000773	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
720554000774	IHF dimer interface [polypeptide binding]; other site
720554000775	IHF - DNA interface [nucleotide binding]; other site
720554000776	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554000777	RNA binding surface [nucleotide binding]; other site
720554000778	YabP family; Region: YabP; cl06766
720554000779	Spore cortex protein YabQ (Spore_YabQ); Region: Spore_YabQ; pfam09578
720554000780	Septum formation initiator; Region: DivIC; pfam04977
720554000781	hypothetical protein; Provisional; Region: PRK05807
720554000782	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
720554000783	RNA binding site [nucleotide binding]; other site
720554000784	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554000785	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
720554000786	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
720554000787	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
720554000788	TrkA-N domain; Region: TrkA_N; pfam02254
720554000789	TrkA-C domain; Region: TrkA_C; pfam02080
720554000790	TrkA-N domain; Region: TrkA_N; pfam02254
720554000791	TrkA-C domain; Region: TrkA_C; pfam02080
720554000792	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554000793	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554000794	Integrase core domain; Region: rve; pfam00665
720554000795	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554000796	MULE transposase domain; Region: MULE; pfam10551
720554000797	Transposase; Region: HTH_Tnp_1; cl17663
720554000798	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554000799	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554000800	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
720554000801	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
720554000802	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000803	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000804	Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Region: Endoglucanase_E_like; cd01831
720554000805	active site
720554000806	catalytic triad [active]
720554000807	oxyanion hole [active]
720554000808	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554000809	Coenzyme A binding pocket [chemical binding]; other site
720554000810	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554000811	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554000812	putative Zn2+ binding site [ion binding]; other site
720554000813	putative DNA binding site [nucleotide binding]; other site
720554000814	Integrase core domain; Region: rve; pfam00665
720554000815	transposase; Provisional; Region: PRK06526
720554000816	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000817	Walker A motif; other site
720554000818	ATP binding site [chemical binding]; other site
720554000819	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554000820	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
720554000821	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554000822	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554000823	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554000824	FtsX-like permease family; Region: FtsX; pfam02687
720554000825	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554000826	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554000827	Walker A/P-loop; other site
720554000828	ATP binding site [chemical binding]; other site
720554000829	Q-loop/lid; other site
720554000830	ABC transporter signature motif; other site
720554000831	Walker B; other site
720554000832	D-loop; other site
720554000833	H-loop/switch region; other site
720554000834	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554000835	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554000836	ATP binding site [chemical binding]; other site
720554000837	Mg2+ binding site [ion binding]; other site
720554000838	G-X-G motif; other site
720554000839	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554000840	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554000841	active site
720554000842	phosphorylation site [posttranslational modification]
720554000843	intermolecular recognition site; other site
720554000844	dimerization interface [polypeptide binding]; other site
720554000845	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554000846	DNA binding site [nucleotide binding]
720554000847	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554000848	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554000849	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
720554000850	Walker A/P-loop; other site
720554000851	ATP binding site [chemical binding]; other site
720554000852	Q-loop/lid; other site
720554000853	ABC transporter signature motif; other site
720554000854	Walker B; other site
720554000855	D-loop; other site
720554000856	H-loop/switch region; other site
720554000857	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554000858	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554000859	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554000860	Walker A/P-loop; other site
720554000861	ATP binding site [chemical binding]; other site
720554000862	Q-loop/lid; other site
720554000863	ABC transporter signature motif; other site
720554000864	Walker B; other site
720554000865	D-loop; other site
720554000866	H-loop/switch region; other site
720554000867	ABC-type Co2+ transport system, permease component [Inorganic ion transport and metabolism]; Region: CbiM; cl00397
720554000868	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
720554000869	PDGLE domain; Region: PDGLE; pfam13190
720554000870	cobalt ABC transporter, permease protein CbiQ; Region: CbiQ_TIGR; TIGR02454
720554000871	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
720554000872	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
720554000873	Walker A/P-loop; other site
720554000874	ATP binding site [chemical binding]; other site
720554000875	Q-loop/lid; other site
720554000876	ABC transporter signature motif; other site
720554000877	Walker B; other site
720554000878	D-loop; other site
720554000879	H-loop/switch region; other site
720554000880	YcxB-like protein; Region: YcxB; pfam14317
720554000881	YcxB-like protein; Region: YcxB; pfam14317
720554000882	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554000883	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554000884	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]; Region: PpiB; COG0652
720554000885	active site
720554000886	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
720554000887	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554000888	motif II; other site
720554000889	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
720554000890	ABC1 family; Region: ABC1; cl17513
720554000891	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
720554000892	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
720554000893	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
720554000894	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
720554000895	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554000896	motif II; other site
720554000897	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
720554000898	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
720554000899	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
720554000900	S-layer homology domain; Region: SLH; pfam00395
720554000901	TraB family; Region: TraB; pfam01963
720554000902	Chagasin family peptidase inhibitor I42; Region: Inhibitor_I42; pfam09394
720554000903	Chagasin family peptidase inhibitor I42; Region: Inhibitor_I42; pfam09394
720554000904	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
720554000905	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
720554000906	HSP70 interaction site [polypeptide binding]; other site
720554000907	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
720554000908	substrate binding site [polypeptide binding]; other site
720554000909	dimer interface [polypeptide binding]; other site
720554000910	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
720554000911	Clp amino terminal domain; Region: Clp_N; pfam02861
720554000912	Clp amino terminal domain; Region: Clp_N; pfam02861
720554000913	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000914	Walker A motif; other site
720554000915	ATP binding site [chemical binding]; other site
720554000916	Walker B motif; other site
720554000917	arginine finger; other site
720554000918	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554000919	Walker A motif; other site
720554000920	ATP binding site [chemical binding]; other site
720554000921	Walker B motif; other site
720554000922	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
720554000923	DNA methylase; Region: N6_N4_Mtase; cl17433
720554000924	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
720554000925	Uncharacterized conserved protein [Function unknown]; Region: COG2006
720554000926	Domain of unknown function (DUF362); Region: DUF362; pfam04015
720554000927	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
720554000928	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
720554000929	stage II sporulation protein E; Region: spore_II_E; TIGR02865
720554000930	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
720554000931	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554000932	dimerization interface [polypeptide binding]; other site
720554000933	Histidine kinase; Region: His_kinase; pfam06580
720554000934	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554000935	ATP binding site [chemical binding]; other site
720554000936	Mg2+ binding site [ion binding]; other site
720554000937	G-X-G motif; other site
720554000938	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
720554000939	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554000940	active site
720554000941	phosphorylation site [posttranslational modification]
720554000942	intermolecular recognition site; other site
720554000943	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554000944	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554000945	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
720554000946	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
720554000947	PilZ domain; Region: PilZ; pfam07238
720554000948	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
720554000949	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
720554000950	FMN binding site [chemical binding]; other site
720554000951	active site
720554000952	catalytic residues [active]
720554000953	substrate binding site [chemical binding]; other site
720554000954	Competence protein A; Region: Competence_A; pfam11104
720554000955	Cell division protein FtsA; Region: FtsA; cl17206
720554000956	Cell division protein FtsA; Region: FtsA; pfam14450
720554000957	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
720554000958	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554000959	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
720554000960	NlpC/P60 family; Region: NLPC_P60; pfam00877
720554000961	stage V sporulation protein B; Region: spore_V_B; TIGR02900
720554000962	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
720554000963	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
720554000964	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
720554000965	putative dimer interface [polypeptide binding]; other site
720554000966	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
720554000967	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
720554000968	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
720554000969	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
720554000970	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
720554000971	trimer interface [polypeptide binding]; other site
720554000972	active site
720554000973	substrate binding site [chemical binding]; other site
720554000974	CoA binding site [chemical binding]; other site
720554000975	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554000976	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
720554000977	Domain of unknown function (DUF4330); Region: DUF4330; pfam14221
720554000978	O-Antigen ligase; Region: Wzy_C; cl04850
720554000979	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
720554000980	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
720554000981	Uncharacterized conserved protein [Function unknown]; Region: COG0062
720554000982	putative carbohydrate kinase; Provisional; Region: PRK10565
720554000983	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
720554000984	putative substrate binding site [chemical binding]; other site
720554000985	putative ATP binding site [chemical binding]; other site
720554000986	alanine racemase; Reviewed; Region: alr; PRK00053
720554000987	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
720554000988	active site
720554000989	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
720554000990	dimer interface [polypeptide binding]; other site
720554000991	substrate binding site [chemical binding]; other site
720554000992	catalytic residues [active]
720554000993	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864
720554000994	PemK-like protein; Region: PemK; pfam02452
720554000995	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
720554000996	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
720554000997	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554000998	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
720554000999	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
720554001000	polysaccharide pyruvyl transferase CsaB; Region: S_layer_CsaB; TIGR03609
720554001001	Uncharacterized conserved protein [Function unknown]; Region: COG1284
720554001002	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
720554001003	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
720554001004	transketolase; Reviewed; Region: PRK05899
720554001005	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
720554001006	TPP-binding site [chemical binding]; other site
720554001007	dimer interface [polypeptide binding]; other site
720554001008	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
720554001009	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
720554001010	PYR/PP interface [polypeptide binding]; other site
720554001011	dimer interface [polypeptide binding]; other site
720554001012	TPP binding site [chemical binding]; other site
720554001013	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554001014	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
720554001015	Leucine rich repeat; Region: LRR_8; pfam13855
720554001016	Leucine rich repeat; Region: LRR_8; pfam13855
720554001017	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
720554001018	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001019	Leucine-rich repeats; other site
720554001020	Substrate binding site [chemical binding]; other site
720554001021	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001022	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001023	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001024	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001025	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
720554001026	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001027	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001028	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001029	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554001030	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554001031	S-layer homology domain; Region: SLH; pfam00395
720554001032	S-layer homology domain; Region: SLH; pfam00395
720554001033	S-layer homology domain; Region: SLH; pfam00395
720554001034	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001035	Leucine rich repeat; Region: LRR_8; pfam13855
720554001036	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
720554001037	Leucine rich repeat; Region: LRR_8; pfam13855
720554001038	Leucine-rich repeats; other site
720554001039	Substrate binding site [chemical binding]; other site
720554001040	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001041	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001042	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001043	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001044	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001045	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001046	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001047	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554001048	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554001049	S-layer homology domain; Region: SLH; pfam00395
720554001050	S-layer homology domain; Region: SLH; pfam00395
720554001051	S-layer homology domain; Region: SLH; pfam00395
720554001052	Leucine rich repeat; Region: LRR_8; pfam13855
720554001053	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001054	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001055	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
720554001056	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001057	Leucine-rich repeats; other site
720554001058	Substrate binding site [chemical binding]; other site
720554001059	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001060	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001061	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001062	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001063	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001064	Leucine rich repeat; Region: LRR_8; pfam13855
720554001065	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554001066	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554001067	S-layer homology domain; Region: SLH; pfam00395
720554001068	S-layer homology domain; Region: SLH; pfam00395
720554001069	S-layer homology domain; Region: SLH; pfam00395
720554001070	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
720554001071	Substrate binding site [chemical binding]; other site
720554001072	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001073	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001074	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001075	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001076	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001077	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001078	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001079	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001080	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554001081	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554001082	S-layer homology domain; Region: SLH; pfam00395
720554001083	S-layer homology domain; Region: SLH; pfam00395
720554001084	S-layer homology domain; Region: SLH; pfam00395
720554001085	AAA domain; Region: AAA_31; pfam13614
720554001086	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
720554001087	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
720554001088	ATP binding site [chemical binding]; other site
720554001089	Walker A motif; other site
720554001090	hexamer interface [polypeptide binding]; other site
720554001091	Walker B motif; other site
720554001092	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
720554001093	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
720554001094	Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400
720554001095	TPR repeat; Region: TPR_11; pfam13414
720554001096	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554001097	binding surface
720554001098	TPR motif; other site
720554001099	KWG Leptospira; Region: KWG; pfam07656
720554001100	KWG Leptospira; Region: KWG; pfam07656
720554001101	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
720554001102	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
720554001103	phosphopeptide binding site; other site
720554001104	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
720554001105	active site
720554001106	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
720554001107	Catalytic domain of Protein Kinases; Region: PKc; cd00180
720554001108	active site
720554001109	ATP binding site [chemical binding]; other site
720554001110	substrate binding site [chemical binding]; other site
720554001111	activation loop (A-loop); other site
720554001112	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554001113	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554001114	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
720554001115	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
720554001116	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
720554001117	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
720554001118	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554001119	Walker A/P-loop; other site
720554001120	ATP binding site [chemical binding]; other site
720554001121	Q-loop/lid; other site
720554001122	ABC transporter signature motif; other site
720554001123	Walker B; other site
720554001124	D-loop; other site
720554001125	H-loop/switch region; other site
720554001126	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
720554001127	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
720554001128	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554001129	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554001130	Walker A motif; other site
720554001131	ATP binding site [chemical binding]; other site
720554001132	Walker B motif; other site
720554001133	arginine finger; other site
720554001134	Protein of unknown function DUF58; Region: DUF58; pfam01882
720554001135	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
720554001136	von Willebrand factor type A domain; Region: VWA_2; pfam13519
720554001137	metal ion-dependent adhesion site (MIDAS); other site
720554001138	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554001139	metal ion-dependent adhesion site (MIDAS); other site
720554001140	Protein of unknown function (DUF1355); Region: DUF1355; cl17712
720554001141	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554001142	metal ion-dependent adhesion site (MIDAS); other site
720554001143	Protein of unknown function (DUF1355); Region: DUF1355; cl17712
720554001144	Filamin/ABP280 repeat; Region: Filamin; pfam00630
720554001145	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554001146	MULE transposase domain; Region: MULE; pfam10551
720554001147	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554001148	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554001149	active site
720554001150	phosphorylation site [posttranslational modification]
720554001151	intermolecular recognition site; other site
720554001152	dimerization interface [polypeptide binding]; other site
720554001153	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554001154	DNA binding site [nucleotide binding]
720554001155	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554001156	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554001157	dimerization interface [polypeptide binding]; other site
720554001158	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554001159	dimer interface [polypeptide binding]; other site
720554001160	phosphorylation site [posttranslational modification]
720554001161	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001162	ATP binding site [chemical binding]; other site
720554001163	Mg2+ binding site [ion binding]; other site
720554001164	G-X-G motif; other site
720554001165	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
720554001166	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
720554001167	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
720554001168	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554001169	Walker A/P-loop; other site
720554001170	ATP binding site [chemical binding]; other site
720554001171	Q-loop/lid; other site
720554001172	ABC transporter signature motif; other site
720554001173	Walker B; other site
720554001174	D-loop; other site
720554001175	H-loop/switch region; other site
720554001176	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
720554001177	Tubby C 2; Region: Tub_2; cl02043
720554001178	Protein of unknown function (DUF3237); Region: DUF3237; cl07905
720554001179	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
720554001180	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
720554001181	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
720554001182	Transcriptional regulators [Transcription]; Region: PurR; COG1609
720554001183	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
720554001184	DNA binding site [nucleotide binding]
720554001185	domain linker motif; other site
720554001186	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
720554001187	dimerization interface [polypeptide binding]; other site
720554001188	ligand binding site [chemical binding]; other site
720554001189	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
720554001190	N-terminal domain of cellobiose phosphorylase (CBP) and similar proteins; Region: GH94N_CBP_like; cd11754
720554001191	catalytic domain interface [polypeptide binding]; other site
720554001192	homodimer interface [polypeptide binding]; other site
720554001193	putative active site [active]
720554001194	N-terminal domain of cellodextrin phosphorylase (CDP) and similar proteins; Region: GH94N_CDP_like; cd11752
720554001195	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
720554001196	Bacterial Ig-like domain; Region: Big_5; pfam13205
720554001197	MG2 domain; Region: A2M_N; pfam01835
720554001198	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
720554001199	Alpha-2-macroglobulin family; Region: A2M; pfam00207
720554001200	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554001201	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554001202	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554001203	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554001204	active site
720554001205	phosphorylation site [posttranslational modification]
720554001206	intermolecular recognition site; other site
720554001207	dimerization interface [polypeptide binding]; other site
720554001208	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554001209	DNA binding site [nucleotide binding]
720554001210	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554001211	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554001212	dimerization interface [polypeptide binding]; other site
720554001213	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554001214	dimer interface [polypeptide binding]; other site
720554001215	phosphorylation site [posttranslational modification]
720554001216	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001217	ATP binding site [chemical binding]; other site
720554001218	Mg2+ binding site [ion binding]; other site
720554001219	G-X-G motif; other site
720554001220	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554001221	binding surface
720554001222	TPR motif; other site
720554001223	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
720554001224	Part of AAA domain; Region: AAA_19; pfam13245
720554001225	Family description; Region: UvrD_C_2; pfam13538
720554001226	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
720554001227	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
720554001228	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
720554001229	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
720554001230	DNA interaction; other site
720554001231	Metal-binding active site; metal-binding site
720554001232	Transcriptional regulators [Transcription]; Region: PurR; COG1609
720554001233	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
720554001234	DNA binding site [nucleotide binding]
720554001235	domain linker motif; other site
720554001236	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
720554001237	dimerization interface [polypeptide binding]; other site
720554001238	ligand binding site [chemical binding]; other site
720554001239	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
720554001240	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
720554001241	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
720554001242	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
720554001243	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554001244	Coenzyme A binding pocket [chemical binding]; other site
720554001245	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
720554001246	HsdM N-terminal domain; Region: HsdM_N; pfam12161
720554001247	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554001248	Predicted ATPase [General function prediction only]; Region: COG5293
720554001249	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
720554001250	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554001251	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
720554001252	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554001253	Protein of unknown function DUF45; Region: DUF45; pfam01863
720554001254	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554001255	MULE transposase domain; Region: MULE; pfam10551
720554001256	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
720554001257	Double zinc ribbon; Region: DZR; pfam12773
720554001258	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
720554001259	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554001260	Coenzyme A binding pocket [chemical binding]; other site
720554001261	ornithine carbamoyltransferase; Provisional; Region: PRK00779
720554001262	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
720554001263	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
720554001264	acetylornithine aminotransferase; Provisional; Region: PRK02627
720554001265	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
720554001266	inhibitor-cofactor binding pocket; inhibition site
720554001267	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554001268	catalytic residue [active]
720554001269	PilZ domain; Region: PilZ; pfam07238
720554001270	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
720554001271	feedback inhibition sensing region; other site
720554001272	homohexameric interface [polypeptide binding]; other site
720554001273	nucleotide binding site [chemical binding]; other site
720554001274	N-acetyl-L-glutamate binding site [chemical binding]; other site
720554001275	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
720554001276	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
720554001277	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
720554001278	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
720554001279	Walker A/P-loop; other site
720554001280	ATP binding site [chemical binding]; other site
720554001281	Q-loop/lid; other site
720554001282	ABC transporter signature motif; other site
720554001283	Walker B; other site
720554001284	D-loop; other site
720554001285	H-loop/switch region; other site
720554001286	TOBE domain; Region: TOBE_2; pfam08402
720554001287	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
720554001288	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
720554001289	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
720554001290	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554001291	Walker A/P-loop; other site
720554001292	ATP binding site [chemical binding]; other site
720554001293	Q-loop/lid; other site
720554001294	ABC transporter signature motif; other site
720554001295	Walker B; other site
720554001296	D-loop; other site
720554001297	H-loop/switch region; other site
720554001298	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
720554001299	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
720554001300	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
720554001301	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
720554001302	Peptidase family M23; Region: Peptidase_M23; pfam01551
720554001303	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
720554001304	C-terminal peptidase (prc); Region: prc; TIGR00225
720554001305	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
720554001306	protein binding site [polypeptide binding]; other site
720554001307	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
720554001308	Catalytic dyad [active]
720554001309	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
720554001310	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
720554001311	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554001312	S-adenosylmethionine binding site [chemical binding]; other site
720554001313	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
720554001314	DNA-binding site [nucleotide binding]; DNA binding site
720554001315	RNA-binding motif; other site
720554001316	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
720554001317	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
720554001318	dimerization interface [polypeptide binding]; other site
720554001319	domain crossover interface; other site
720554001320	redox-dependent activation switch; other site
720554001321	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554001322	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554001323	Integrase core domain; Region: rve; pfam00665
720554001324	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
720554001325	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
720554001326	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
720554001327	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554001328	substrate binding pocket [chemical binding]; other site
720554001329	membrane-bound complex binding site; other site
720554001330	hinge residues; other site
720554001331	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
720554001332	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554001333	dimer interface [polypeptide binding]; other site
720554001334	conserved gate region; other site
720554001335	putative PBP binding loops; other site
720554001336	ABC-ATPase subunit interface; other site
720554001337	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
720554001338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554001339	dimer interface [polypeptide binding]; other site
720554001340	conserved gate region; other site
720554001341	putative PBP binding loops; other site
720554001342	ABC-ATPase subunit interface; other site
720554001343	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
720554001344	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
720554001345	Walker A/P-loop; other site
720554001346	ATP binding site [chemical binding]; other site
720554001347	Q-loop/lid; other site
720554001348	ABC transporter signature motif; other site
720554001349	Walker B; other site
720554001350	D-loop; other site
720554001351	H-loop/switch region; other site
720554001352	TOBE-like domain; Region: TOBE_3; pfam12857
720554001353	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
720554001354	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
720554001355	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
720554001356	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
720554001357	active site
720554001358	NAD binding site [chemical binding]; other site
720554001359	metal binding site [ion binding]; metal-binding site
720554001360	carbon-monoxide dehydrogenase, catalytic subunit; Region: CO_DH_cata; TIGR01702
720554001361	Carbon monoxide dehydrogenase (CODH) is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA, respectively. CODH has two types of metal clusters, a cubane [Fe4-S4] center (B-cluster) similar to...; Region: CODH; cd01915
720554001362	ACS interaction site; other site
720554001363	CODH interaction site; other site
720554001364	cubane metal cluster (B-cluster) [ion binding]; other site
720554001365	Ni-Fe-S cluster (C-cluster) [ion binding]; other site
720554001366	Response regulator receiver domain; Region: Response_reg; pfam00072
720554001367	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554001368	active site
720554001369	phosphorylation site [posttranslational modification]
720554001370	intermolecular recognition site; other site
720554001371	dimerization interface [polypeptide binding]; other site
720554001372	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554001373	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554001374	metal binding site [ion binding]; metal-binding site
720554001375	active site
720554001376	I-site; other site
720554001377	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
720554001378	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
720554001379	peptide binding site [polypeptide binding]; other site
720554001380	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
720554001381	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
720554001382	Histidine kinase; Region: HisKA_3; pfam07730
720554001383	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001384	ATP binding site [chemical binding]; other site
720554001385	Mg2+ binding site [ion binding]; other site
720554001386	G-X-G motif; other site
720554001387	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
720554001388	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
720554001389	active site
720554001390	metal binding site [ion binding]; metal-binding site
720554001391	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554001392	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554001393	Bacterial SH3 domain; Region: SH3_3; pfam08239
720554001394	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554001395	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554001396	Transposase; Region: HTH_Tnp_1; pfam01527
720554001397	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554001398	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554001399	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554001400	Predicted glycosyl hydrolase [General function prediction only]; Region: COG3858
720554001401	Bacterial SH3 domain; Region: SH3_3; pfam08239
720554001402	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in  bacterial endospore germination.  CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells.  SleB translocates across the...; Region: GH18_CFLE_spore_hydrolase; cd02874
720554001403	active site
720554001404	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
720554001405	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
720554001406	CoA binding domain; Region: CoA_binding; smart00881
720554001407	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
720554001408	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
720554001409	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
720554001410	ABC transporter; Region: ABC_tran_2; pfam12848
720554001411	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
720554001412	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554001413	Transposase; Region: HTH_Tnp_1; pfam01527
720554001414	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554001415	putative transposase OrfB; Reviewed; Region: PHA02517
720554001416	HTH-like domain; Region: HTH_21; pfam13276
720554001417	Integrase core domain; Region: rve; pfam00665
720554001418	Integrase core domain; Region: rve_3; pfam13683
720554001419	prephenate dehydrogenase; Validated; Region: PRK08507
720554001420	prephenate dehydrogenase; Validated; Region: PRK06545
720554001421	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
720554001422	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
720554001423	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
720554001424	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
720554001425	elongation factor G; Reviewed; Region: PRK12740
720554001426	G1 box; other site
720554001427	putative GEF interaction site [polypeptide binding]; other site
720554001428	GTP/Mg2+ binding site [chemical binding]; other site
720554001429	Switch I region; other site
720554001430	G2 box; other site
720554001431	G3 box; other site
720554001432	Switch II region; other site
720554001433	G4 box; other site
720554001434	G5 box; other site
720554001435	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
720554001436	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
720554001437	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
720554001438	Protein of unknown function (DUF1624); Region: DUF1624; pfam07786
720554001439	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
720554001440	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
720554001441	UvrB/uvrC motif; Region: UVR; pfam02151
720554001442	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
720554001443	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
720554001444	ADP binding site [chemical binding]; other site
720554001445	phosphagen binding site; other site
720554001446	substrate specificity loop; other site
720554001447	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
720554001448	Clp amino terminal domain; Region: Clp_N; pfam02861
720554001449	Clp amino terminal domain; Region: Clp_N; pfam02861
720554001450	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554001451	Walker A motif; other site
720554001452	ATP binding site [chemical binding]; other site
720554001453	Walker B motif; other site
720554001454	arginine finger; other site
720554001455	UvrB/uvrC motif; Region: UVR; pfam02151
720554001456	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554001457	Walker A motif; other site
720554001458	ATP binding site [chemical binding]; other site
720554001459	Walker B motif; other site
720554001460	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
720554001461	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
720554001462	Tim44-like domain; Region: Tim44; cl09208
720554001463	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
720554001464	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
720554001465	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
720554001466	Double zinc ribbon; Region: DZR; pfam12773
720554001467	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
720554001468	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554001469	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554001470	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
720554001471	Protein of unknown function DUF58; Region: DUF58; pfam01882
720554001472	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554001473	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554001474	Walker A motif; other site
720554001475	ATP binding site [chemical binding]; other site
720554001476	Walker B motif; other site
720554001477	arginine finger; other site
720554001478	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554001479	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554001480	Integrase core domain; Region: rve; pfam00665
720554001481	HAMP domain; Region: HAMP; pfam00672
720554001482	GAF domain; Region: GAF_2; pfam13185
720554001483	GAF domain; Region: GAF_3; pfam13492
720554001484	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554001485	dimer interface [polypeptide binding]; other site
720554001486	phosphorylation site [posttranslational modification]
720554001487	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001488	ATP binding site [chemical binding]; other site
720554001489	Mg2+ binding site [ion binding]; other site
720554001490	G-X-G motif; other site
720554001491	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
720554001492	putative active site [active]
720554001493	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
720554001494	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
720554001495	DXD motif; other site
720554001496	oligosaccharide amylase; Region: oligosac_amyl; TIGR01577
720554001497	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
720554001498	DNA repair protein RadA; Provisional; Region: PRK11823
720554001499	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
720554001500	Walker A motif/ATP binding site; other site
720554001501	ATP binding site [chemical binding]; other site
720554001502	Walker B motif; other site
720554001503	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
720554001504	DNA integrity scanning protein DisA; Provisional; Region: PRK13482
720554001505	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
720554001506	DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635
720554001507	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
720554001508	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
720554001509	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
720554001510	substrate binding site; other site
720554001511	dimer interface; other site
720554001512	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
720554001513	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554001514	Walker A/P-loop; other site
720554001515	ATP binding site [chemical binding]; other site
720554001516	Q-loop/lid; other site
720554001517	ABC transporter signature motif; other site
720554001518	Walker B; other site
720554001519	D-loop; other site
720554001520	H-loop/switch region; other site
720554001521	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
720554001522	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
720554001523	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554001524	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001525	ATP binding site [chemical binding]; other site
720554001526	Mg2+ binding site [ion binding]; other site
720554001527	G-X-G motif; other site
720554001528	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554001529	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001530	ATP binding site [chemical binding]; other site
720554001531	Mg2+ binding site [ion binding]; other site
720554001532	G-X-G motif; other site
720554001533	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
720554001534	homotrimer interaction site [polypeptide binding]; other site
720554001535	zinc binding site [ion binding]; other site
720554001536	CDP-binding sites; other site
720554001537	Bacterial SH3 domain; Region: SH3_3; pfam08239
720554001538	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
720554001539	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
720554001540	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
720554001541	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_9; cd13135
720554001542	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
720554001543	active site
720554001544	dimerization interface [polypeptide binding]; other site
720554001545	Protein of unknown function DUF84; Region: NTPase_I-T; cl00866
720554001546	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
720554001547	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
720554001548	Beta-lactamase; Region: Beta-lactamase; pfam00144
720554001549	FkbH-like domain; Region: FkbH; TIGR01686
720554001550	Acid Phosphatase; Region: Acid_PPase; cl17256
720554001551	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554001552	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
720554001553	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
720554001554	active site
720554001555	TDP-binding site; other site
720554001556	acceptor substrate-binding pocket; other site
720554001557	homodimer interface [polypeptide binding]; other site
720554001558	Condensation domain; Region: Condensation; pfam00668
720554001559	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
720554001560	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
720554001561	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554001562	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
720554001563	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554001564	RNA binding surface [nucleotide binding]; other site
720554001565	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
720554001566	active site
720554001567	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
720554001568	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
720554001569	active site
720554001570	Substrate binding site; other site
720554001571	Mg++ binding site; other site
720554001572	putative trimer interface [polypeptide binding]; other site
720554001573	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
720554001574	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
720554001575	putative CoA binding site [chemical binding]; other site
720554001576	putative trimer interface [polypeptide binding]; other site
720554001577	putative CoA binding site [chemical binding]; other site
720554001578	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
720554001579	GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity.  The protein contains an...; Region: MPG1_transferase; cd05805
720554001580	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
720554001581	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554001582	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554001583	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554001584	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
720554001585	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
720554001586	homotrimer interaction site [polypeptide binding]; other site
720554001587	putative active site [active]
720554001588	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
720554001589	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554001590	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554001591	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554001592	S-adenosylmethionine binding site [chemical binding]; other site
720554001593	putative UV damage endonuclease; Provisional; Region: uvsE; PRK02308
720554001594	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
720554001595	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
720554001596	putative substrate binding site [chemical binding]; other site
720554001597	putative ATP binding site [chemical binding]; other site
720554001598	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554001599	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554001600	active site
720554001601	phosphorylation site [posttranslational modification]
720554001602	intermolecular recognition site; other site
720554001603	dimerization interface [polypeptide binding]; other site
720554001604	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554001605	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554001606	metal binding site [ion binding]; metal-binding site
720554001607	active site
720554001608	I-site; other site
720554001609	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
720554001610	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
720554001611	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
720554001612	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
720554001613	RNA binding site [nucleotide binding]; other site
720554001614	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
720554001615	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554001616	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
720554001617	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
720554001618	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
720554001619	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
720554001620	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
720554001621	catalytic residues [active]
720554001622	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
720554001623	catalytic residues [active]
720554001624	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
720554001625	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554001626	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554001627	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
720554001628	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554001629	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
720554001630	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554001631	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554001632	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
720554001633	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
720554001634	active site residue [active]
720554001635	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436
720554001636	CPxP  motif; other site
720554001637	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
720554001638	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554001639	dimerization interface [polypeptide binding]; other site
720554001640	putative DNA binding site [nucleotide binding]; other site
720554001641	putative Zn2+ binding site [ion binding]; other site
720554001642	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
720554001643	intersubunit interface [polypeptide binding]; other site
720554001644	active site
720554001645	catalytic residue [active]
720554001646	Sporulation and spore germination; Region: Germane; pfam10646
720554001647	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
720554001648	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554001649	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554001650	DNA binding residues [nucleotide binding]
720554001651	anti-sigma factor, putative, ChrR family; Region: anti_sig_ChrR; TIGR02451
720554001652	PQQ-like domain; Region: PQQ_2; pfam13360
720554001653	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
720554001654	Trp docking motif [polypeptide binding]; other site
720554001655	active site
720554001656	Transthyretin-like family; Region: DUF290; pfam01060
720554001657	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
720554001658	Zn binding site [ion binding]; other site
720554001659	S-layer homology domain; Region: SLH; pfam00395
720554001660	S-layer homology domain; Region: SLH; pfam00395
720554001661	S-layer homology domain; Region: SLH; pfam00395
720554001662	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
720554001663	Domain of unknown function DUF87; Region: DUF87; pfam01935
720554001664	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
720554001665	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
720554001666	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
720554001667	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
720554001668	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
720554001669	glutamate racemase; Provisional; Region: PRK00865
720554001670	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
720554001671	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
720554001672	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
720554001673	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
720554001674	active site
720554001675	HIGH motif; other site
720554001676	KMSK motif region; other site
720554001677	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
720554001678	tRNA binding surface [nucleotide binding]; other site
720554001679	anticodon binding site; other site
720554001680	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
720554001681	Beta-lactamase superfamily domain; Region: Lactamase_B_3; pfam13483
720554001682	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
720554001683	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
720554001684	dimer interface [polypeptide binding]; other site
720554001685	PYR/PP interface [polypeptide binding]; other site
720554001686	TPP binding site [chemical binding]; other site
720554001687	substrate binding site [chemical binding]; other site
720554001688	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
720554001689	Domain of unknown function; Region: EKR; smart00890
720554001690	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554001691	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
720554001692	TPP-binding site [chemical binding]; other site
720554001693	dimer interface [polypeptide binding]; other site
720554001694	S-layer homology domain; Region: SLH; pfam00395
720554001695	S-layer homology domain; Region: SLH; pfam00395
720554001696	S-layer homology domain; Region: SLH; pfam00395
720554001697	S-layer homology domain; Region: SLH; pfam00395
720554001698	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
720554001699	C-terminal peptidase (prc); Region: prc; TIGR00225
720554001700	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
720554001701	protein binding site [polypeptide binding]; other site
720554001702	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
720554001703	Catalytic dyad [active]
720554001704	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
720554001705	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554001706	CTP synthetase; Validated; Region: pyrG; PRK05380
720554001707	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
720554001708	Catalytic site [active]
720554001709	active site
720554001710	UTP binding site [chemical binding]; other site
720554001711	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
720554001712	active site
720554001713	putative oxyanion hole; other site
720554001714	catalytic triad [active]
720554001715	Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; pfam09551
720554001716	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
720554001717	MgtC family; Region: MgtC; pfam02308
720554001718	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
720554001719	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
720554001720	homodimer interface [polypeptide binding]; other site
720554001721	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554001722	catalytic residue [active]
720554001723	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
720554001724	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
720554001725	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
720554001726	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
720554001727	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
720554001728	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554001729	motif II; other site
720554001730	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
720554001731	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
720554001732	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554001733	Walker A/P-loop; other site
720554001734	ATP binding site [chemical binding]; other site
720554001735	Q-loop/lid; other site
720554001736	ABC transporter signature motif; other site
720554001737	Walker B; other site
720554001738	D-loop; other site
720554001739	H-loop/switch region; other site
720554001740	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
720554001741	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
720554001742	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
720554001743	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
720554001744	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
720554001745	Uncharacterized membrane protein [Function unknown]; Region: COG3949
720554001746	Colicin V production protein; Region: Colicin_V; pfam02674
720554001747	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
720554001748	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK06048
720554001749	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
720554001750	PYR/PP interface [polypeptide binding]; other site
720554001751	dimer interface [polypeptide binding]; other site
720554001752	TPP binding site [chemical binding]; other site
720554001753	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
720554001754	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
720554001755	TPP-binding site [chemical binding]; other site
720554001756	dimer interface [polypeptide binding]; other site
720554001757	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
720554001758	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
720554001759	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
720554001760	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
720554001761	putative homodimer interface [polypeptide binding]; other site
720554001762	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
720554001763	heterodimer interface [polypeptide binding]; other site
720554001764	homodimer interface [polypeptide binding]; other site
720554001765	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
720554001766	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
720554001767	23S rRNA interface [nucleotide binding]; other site
720554001768	L7/L12 interface [polypeptide binding]; other site
720554001769	putative thiostrepton binding site; other site
720554001770	L25 interface [polypeptide binding]; other site
720554001771	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
720554001772	mRNA/rRNA interface [nucleotide binding]; other site
720554001773	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
720554001774	23S rRNA interface [nucleotide binding]; other site
720554001775	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
720554001776	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
720554001777	core dimer interface [polypeptide binding]; other site
720554001778	peripheral dimer interface [polypeptide binding]; other site
720554001779	L10 interface [polypeptide binding]; other site
720554001780	L11 interface [polypeptide binding]; other site
720554001781	putative EF-Tu interaction site [polypeptide binding]; other site
720554001782	putative EF-G interaction site [polypeptide binding]; other site
720554001783	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
720554001784	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
720554001785	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
720554001786	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
720554001787	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
720554001788	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
720554001789	RPB10 interaction site [polypeptide binding]; other site
720554001790	RPB1 interaction site [polypeptide binding]; other site
720554001791	RPB11 interaction site [polypeptide binding]; other site
720554001792	RPB3 interaction site [polypeptide binding]; other site
720554001793	RPB12 interaction site [polypeptide binding]; other site
720554001794	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
720554001795	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
720554001796	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
720554001797	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
720554001798	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
720554001799	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
720554001800	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
720554001801	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
720554001802	G-loop; other site
720554001803	DNA binding site [nucleotide binding]
720554001804	putative ribosomal protein L7Ae-like; Provisional; Region: PRK13602
720554001805	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
720554001806	S17 interaction site [polypeptide binding]; other site
720554001807	S8 interaction site; other site
720554001808	16S rRNA interaction site [nucleotide binding]; other site
720554001809	streptomycin interaction site [chemical binding]; other site
720554001810	23S rRNA interaction site [nucleotide binding]; other site
720554001811	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
720554001812	30S ribosomal protein S7; Validated; Region: PRK05302
720554001813	elongation factor G; Reviewed; Region: PRK00007
720554001814	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
720554001815	G1 box; other site
720554001816	putative GEF interaction site [polypeptide binding]; other site
720554001817	GTP/Mg2+ binding site [chemical binding]; other site
720554001818	Switch I region; other site
720554001819	G2 box; other site
720554001820	G3 box; other site
720554001821	Switch II region; other site
720554001822	G4 box; other site
720554001823	G5 box; other site
720554001824	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
720554001825	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
720554001826	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
720554001827	elongation factor Tu; Reviewed; Region: PRK00049
720554001828	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
720554001829	G1 box; other site
720554001830	GEF interaction site [polypeptide binding]; other site
720554001831	GTP/Mg2+ binding site [chemical binding]; other site
720554001832	Switch I region; other site
720554001833	G2 box; other site
720554001834	G3 box; other site
720554001835	Switch II region; other site
720554001836	G4 box; other site
720554001837	G5 box; other site
720554001838	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
720554001839	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
720554001840	Antibiotic Binding Site [chemical binding]; other site
720554001841	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
720554001842	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554001843	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554001844	DNA binding residues [nucleotide binding]
720554001845	Putative zinc-finger; Region: zf-HC2; pfam13490
720554001846	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
720554001847	VanW like protein; Region: VanW; pfam04294
720554001848	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
720554001849	dimerization domain swap beta strand [polypeptide binding]; other site
720554001850	regulatory protein interface [polypeptide binding]; other site
720554001851	active site
720554001852	regulatory phosphorylation site [posttranslational modification]; other site
720554001853	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
720554001854	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
720554001855	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
720554001856	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
720554001857	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
720554001858	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
720554001859	GIY-YIG motif/motif A; other site
720554001860	active site
720554001861	catalytic site [active]
720554001862	putative DNA binding site [nucleotide binding]; other site
720554001863	metal binding site [ion binding]; metal-binding site
720554001864	UvrB/uvrC motif; Region: UVR; pfam02151
720554001865	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
720554001866	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
720554001867	DNA binding site [nucleotide binding]
720554001868	Deinococcus radiodurans DR1119 and related proteins, metallophosphatase domain; Region: MPP_DR1119; cd07393
720554001869	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
720554001870	putative active site [active]
720554001871	putative metal binding site [ion binding]; other site
720554001872	trigger factor; Provisional; Region: tig; PRK01490
720554001873	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
720554001874	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
720554001875	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
720554001876	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
720554001877	oligomer interface [polypeptide binding]; other site
720554001878	active site residues [active]
720554001879	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
720554001880	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
720554001881	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554001882	Walker A motif; other site
720554001883	ATP binding site [chemical binding]; other site
720554001884	Walker B motif; other site
720554001885	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
720554001886	ATP-dependent protease LonB; Region: spore_lonB; TIGR02902
720554001887	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554001888	Walker A motif; other site
720554001889	ATP binding site [chemical binding]; other site
720554001890	Walker B motif; other site
720554001891	arginine finger; other site
720554001892	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
720554001893	UGMP family protein; Validated; Region: PRK09604
720554001894	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
720554001895	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554001896	FeS/SAM binding site; other site
720554001897	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
720554001898	Protein of unknown function (DUF512); Region: DUF512; pfam04459
720554001899	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
720554001900	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
720554001901	N-acetyl-D-glucosamine binding site [chemical binding]; other site
720554001902	catalytic residue [active]
720554001903	Protein of unknown function (DUF402); Region: DUF402; pfam04167
720554001904	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
720554001905	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
720554001906	active site
720554001907	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
720554001908	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
720554001909	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
720554001910	SmpB-tmRNA interface; other site
720554001911	Helix-turn-helix domain; Region: HTH_17; pfam12728
720554001912	Domain of unknown function (DUF4373); Region: DUF4373; pfam14297
720554001913	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554001914	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554001915	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554001916	Mu-like prophage protein [General function prediction only]; Region: COG3941
720554001917	RNA polymerase factor sigma-70; Validated; Region: PRK08295
720554001918	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554001919	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554001920	non-specific DNA binding site [nucleotide binding]; other site
720554001921	salt bridge; other site
720554001922	sequence-specific DNA binding site [nucleotide binding]; other site
720554001923	Domain of unknown function (DUF4375); Region: DUF4375; pfam14300
720554001924	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554001925	Transposase; Region: HTH_Tnp_1; pfam01527
720554001926	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554001927	putative transposase OrfB; Reviewed; Region: PHA02517
720554001928	HTH-like domain; Region: HTH_21; pfam13276
720554001929	Integrase core domain; Region: rve; pfam00665
720554001930	Integrase core domain; Region: rve_3; pfam13683
720554001931	Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600
720554001932	Reductive dehalogenase subunit; Region: Dehalogenase; pfam13486
720554001933	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
720554001934	dinuclear metal binding motif [ion binding]; other site
720554001935	Staygreen protein; Region: Staygreen; pfam12638
720554001936	Carbohydrate Binding Module family 35 (CBM35), pectate lyase-like; appended mainly to enzymes that bind mannan (Man), xylan, glucuronic acid (GlcA) and possibly glucans; Region: CBM35_pectate_lyase-like; cd04082
720554001937	Ca binding site [ion binding]; other site
720554001938	Ca binding site (active) [ion binding]; other site
720554001939	ligand binding site [chemical binding]; other site
720554001940	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554001941	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554001942	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554001943	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554001944	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554001945	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554001946	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
720554001947	HSP70 interaction site [polypeptide binding]; other site
720554001948	Domain of Unknown Function with PDB structure (DUF3862); Region: DUF3862; pfam12978
720554001949	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554001950	MULE transposase domain; Region: MULE; pfam10551
720554001951	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
720554001952	binding surface
720554001953	TPR motif; other site
720554001954	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554001955	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
720554001956	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
720554001957	ATP cone domain; Region: ATP-cone; pfam03477
720554001958	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
720554001959	Class III ribonucleotide reductase; Region: RNR_III; cd01675
720554001960	active site
720554001961	Zn binding site [ion binding]; other site
720554001962	glycine loop; other site
720554001963	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
720554001964	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554001965	FeS/SAM binding site; other site
720554001966	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
720554001967	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
720554001968	peptide binding site [polypeptide binding]; other site
720554001969	Cache domain; Region: Cache_1; pfam02743
720554001970	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
720554001971	Histidine kinase; Region: HisKA_3; pfam07730
720554001972	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554001973	ATP binding site [chemical binding]; other site
720554001974	Mg2+ binding site [ion binding]; other site
720554001975	G-X-G motif; other site
720554001976	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
720554001977	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554001978	active site
720554001979	phosphorylation site [posttranslational modification]
720554001980	intermolecular recognition site; other site
720554001981	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
720554001982	DNA binding residues [nucleotide binding]
720554001983	dimerization interface [polypeptide binding]; other site
720554001984	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
720554001985	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554001986	Coenzyme A binding pocket [chemical binding]; other site
720554001987	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
720554001988	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
720554001989	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
720554001990	TAP-like protein; Region: Abhydrolase_4; pfam08386
720554001991	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554001992	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
720554001993	WYL domain; Region: WYL; pfam13280
720554001994	WYL domain; Region: WYL; pfam13280
720554001995	TROVE domain; Region: TROVE; pfam05731
720554001996	RNA repair, ligase-Pnkp-associating, region of Hen1; Region: Hen1_L; pfam12623
720554001997	3' terminal RNA ribose 2'-O-methyltransferase Hen1; Region: bacter_Hen1; TIGR04074
720554001998	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554001999	S-adenosylmethionine binding site [chemical binding]; other site
720554002000	polynucleotide kinase-phosphatase; Region: bacter_Pnkp; TIGR04075
720554002001	Bacillus subtilis PrpE and related proteins, metallophosphatase domain; Region: MPP_PrpE; cd07423
720554002002	active site
720554002003	metal binding site [ion binding]; metal-binding site
720554002004	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
720554002005	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
720554002006	active site
720554002007	Transposase domain (DUF772); Region: DUF772; pfam05598
720554002008	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554002009	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554002010	4Fe-4S binding domain; Region: Fer4_5; pfam12801
720554002011	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
720554002012	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
720554002013	Transposase domain (DUF772); Region: DUF772; pfam05598
720554002014	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554002015	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554002016	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554002017	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
720554002018	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; cl00614
720554002019	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
720554002020	nicotinamide-nucleotide adenylyltransferase, NadR type; Region: nadR_NMN_Atrans; TIGR01526
720554002021	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
720554002022	active site
720554002023	nucleotide binding site [chemical binding]; other site
720554002024	HIGH motif; other site
720554002025	KMSKS motif; other site
720554002026	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
720554002027	Predicted membrane protein [Function unknown]; Region: COG3212
720554002028	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
720554002029	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
720554002030	dimanganese center [ion binding]; other site
720554002031	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
720554002032	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
720554002033	dimer interface [polypeptide binding]; other site
720554002034	PYR/PP interface [polypeptide binding]; other site
720554002035	TPP binding site [chemical binding]; other site
720554002036	substrate binding site [chemical binding]; other site
720554002037	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
720554002038	Domain of unknown function; Region: EKR; pfam10371
720554002039	4Fe-4S binding domain; Region: Fer4_6; pfam12837
720554002040	4Fe-4S binding domain; Region: Fer4; pfam00037
720554002041	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
720554002042	TPP-binding site [chemical binding]; other site
720554002043	dimer interface [polypeptide binding]; other site
720554002044	Domain of unknown function (DUF3787); Region: DUF3787; pfam12655
720554002045	biotin synthase; Region: bioB; TIGR00433
720554002046	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554002047	FeS/SAM binding site; other site
720554002048	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
720554002049	RNA 2'-phosphotransferase, Tpt1 / KptA family; Region: PTS_2-RNA; pfam01885
720554002050	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
720554002051	Domain of unknown function (DUF4272); Region: DUF4272; pfam14094
720554002052	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
720554002053	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554002054	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
720554002055	Putative esterase; Region: Esterase; pfam00756
720554002056	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
720554002057	Ubiquitin-like proteins; Region: UBQ; cl00155
720554002058	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554002059	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554002060	dimer interface [polypeptide binding]; other site
720554002061	putative CheW interface [polypeptide binding]; other site
720554002062	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
720554002063	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
720554002064	ligand binding site [chemical binding]; other site
720554002065	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554002066	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554002067	dimer interface [polypeptide binding]; other site
720554002068	putative CheW interface [polypeptide binding]; other site
720554002069	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
720554002070	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
720554002071	ligand binding site [chemical binding]; other site
720554002072	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554002073	Accessory gene regulator B; Region: AgrB; pfam04647
720554002074	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
720554002075	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
720554002076	Walker A/P-loop; other site
720554002077	ATP binding site [chemical binding]; other site
720554002078	Q-loop/lid; other site
720554002079	ABC transporter signature motif; other site
720554002080	Walker B; other site
720554002081	D-loop; other site
720554002082	H-loop/switch region; other site
720554002083	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732
720554002084	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
720554002085	lantibiotic protection ABC transporter permease subunit, MutG family; Region: lanti_perm_MutG; TIGR03733
720554002086	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
720554002087	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554002088	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554002089	active site
720554002090	phosphorylation site [posttranslational modification]
720554002091	intermolecular recognition site; other site
720554002092	dimerization interface [polypeptide binding]; other site
720554002093	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554002094	DNA binding site [nucleotide binding]
720554002095	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554002096	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554002097	dimerization interface [polypeptide binding]; other site
720554002098	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554002099	dimer interface [polypeptide binding]; other site
720554002100	phosphorylation site [posttranslational modification]
720554002101	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554002102	ATP binding site [chemical binding]; other site
720554002103	Mg2+ binding site [ion binding]; other site
720554002104	G-X-G motif; other site
720554002105	Predicted nucleotidyltransferase [General function prediction only]; Region: COG3541
720554002106	Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417
720554002107	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
720554002108	active site
720554002109	catalytic motif [active]
720554002110	Zn binding site [ion binding]; other site
720554002111	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
720554002112	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
720554002113	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
720554002114	methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370
720554002115	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
720554002116	B12 binding site [chemical binding]; other site
720554002117	cobalt ligand [ion binding]; other site
720554002118	Sensory domain found in PocR; Region: PocR; pfam10114
720554002119	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
720554002120	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554002121	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554002122	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554002123	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
720554002124	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
720554002125	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
720554002126	Methanol-cobalamin methyltransferase B subunit; Region: MtaB; pfam12176
720554002127	Protein of unknown function (DUF1638); Region: DUF1638; pfam07796
720554002128	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
720554002129	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
720554002130	putative dimer interface [polypeptide binding]; other site
720554002131	active site pocket [active]
720554002132	putative cataytic base [active]
720554002133	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
720554002134	Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894
720554002135	catalytic loop [active]
720554002136	iron binding site [ion binding]; other site
720554002137	Transcriptional regulators [Transcription]; Region: PurR; COG1609
720554002138	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
720554002139	DNA binding site [nucleotide binding]
720554002140	domain linker motif; other site
720554002141	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
720554002142	dimerization interface [polypeptide binding]; other site
720554002143	ligand binding site [chemical binding]; other site
720554002144	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
720554002145	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
720554002146	substrate binding site [chemical binding]; other site
720554002147	dimer interface [polypeptide binding]; other site
720554002148	ATP binding site [chemical binding]; other site
720554002149	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
720554002150	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
720554002151	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
720554002152	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
720554002153	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
720554002154	TM-ABC transporter signature motif; other site
720554002155	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
720554002156	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
720554002157	Walker A/P-loop; other site
720554002158	ATP binding site [chemical binding]; other site
720554002159	Q-loop/lid; other site
720554002160	ABC transporter signature motif; other site
720554002161	Walker B; other site
720554002162	D-loop; other site
720554002163	H-loop/switch region; other site
720554002164	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
720554002165	D-ribose pyranase; Provisional; Region: PRK11797
720554002166	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
720554002167	active site
720554002168	catalytic residues [active]
720554002169	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
720554002170	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
720554002171	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
720554002172	active site
720554002173	ribonuclease Z; Reviewed; Region: PRK00055
720554002174	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
720554002175	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
720554002176	synthetase active site [active]
720554002177	NTP binding site [chemical binding]; other site
720554002178	metal binding site [ion binding]; metal-binding site
720554002179	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554002180	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554002181	Integrase core domain; Region: rve; pfam00665
720554002182	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554002183	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554002184	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554002185	Walker A/P-loop; other site
720554002186	ATP binding site [chemical binding]; other site
720554002187	Q-loop/lid; other site
720554002188	ABC transporter signature motif; other site
720554002189	Walker B; other site
720554002190	D-loop; other site
720554002191	H-loop/switch region; other site
720554002192	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554002193	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554002194	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
720554002195	Walker A/P-loop; other site
720554002196	ATP binding site [chemical binding]; other site
720554002197	Q-loop/lid; other site
720554002198	ABC transporter signature motif; other site
720554002199	Walker B; other site
720554002200	D-loop; other site
720554002201	H-loop/switch region; other site
720554002202	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002203	NPCBM/NEW2 domain; Region: NPCBM; cl07060
720554002204	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554002205	Prismane/CO dehydrogenase family; Region: Prismane; pfam03063
720554002206	ACS interaction site; other site
720554002207	CODH interaction site; other site
720554002208	metal cluster binding site [ion binding]; other site
720554002209	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
720554002210	NMT1-like family; Region: NMT1_2; pfam13379
720554002211	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554002212	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554002213	dimer interface [polypeptide binding]; other site
720554002214	conserved gate region; other site
720554002215	putative PBP binding loops; other site
720554002216	ABC-ATPase subunit interface; other site
720554002217	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
720554002218	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
720554002219	Walker A/P-loop; other site
720554002220	ATP binding site [chemical binding]; other site
720554002221	Q-loop/lid; other site
720554002222	ABC transporter signature motif; other site
720554002223	Walker B; other site
720554002224	D-loop; other site
720554002225	H-loop/switch region; other site
720554002226	HlyD family secretion protein; Region: HlyD; pfam00529
720554002227	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
720554002228	HlyD family secretion protein; Region: HlyD_3; pfam13437
720554002229	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554002230	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554002231	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554002232	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554002233	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554002234	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554002235	Transposase domain (DUF772); Region: DUF772; pfam05598
720554002236	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554002237	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554002238	MULE transposase domain; Region: MULE; pfam10551
720554002239	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
720554002240	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
720554002241	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
720554002242	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
720554002243	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554002244	protein-splicing catalytic site; other site
720554002245	thioester formation/cholesterol transfer; other site
720554002246	transposase; Provisional; Region: PRK06526
720554002247	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554002248	Walker A motif; other site
720554002249	ATP binding site [chemical binding]; other site
720554002250	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554002251	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554002252	putative Zn2+ binding site [ion binding]; other site
720554002253	putative DNA binding site [nucleotide binding]; other site
720554002254	Integrase core domain; Region: rve; pfam00665
720554002255	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
720554002256	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
720554002257	active site
720554002258	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
720554002259	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554002260	binding surface
720554002261	TPR repeat; Region: TPR_11; pfam13414
720554002262	TPR motif; other site
720554002263	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
720554002264	binding surface
720554002265	TPR motif; other site
720554002266	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
720554002267	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
720554002268	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
720554002269	Proteins of 100 residues with WXG; Region: WXG100; cl02005
720554002270	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
720554002271	FMN binding site [chemical binding]; other site
720554002272	dimer interface [polypeptide binding]; other site
720554002273	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
720554002274	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
720554002275	active site
720554002276	metal binding site [ion binding]; metal-binding site
720554002277	nudix motif; other site
720554002278	Aromatic prenyltransferase Orf2; Region: PTase_Orf2; pfam11468
720554002279	peroxiredoxin; Region: AhpC; TIGR03137
720554002280	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
720554002281	dimer interface [polypeptide binding]; other site
720554002282	decamer (pentamer of dimers) interface [polypeptide binding]; other site
720554002283	catalytic triad [active]
720554002284	peroxidatic and resolving cysteines [active]
720554002285	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
720554002286	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
720554002287	catalytic residue [active]
720554002288	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
720554002289	catalytic residues [active]
720554002290	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554002291	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554002292	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
720554002293	Transposase domain (DUF772); Region: DUF772; pfam05598
720554002294	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554002295	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554002296	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
720554002297	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
720554002298	peptide binding site [polypeptide binding]; other site
720554002299	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
720554002300	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
720554002301	Walker A/P-loop; other site
720554002302	ATP binding site [chemical binding]; other site
720554002303	Q-loop/lid; other site
720554002304	ABC transporter signature motif; other site
720554002305	Walker B; other site
720554002306	D-loop; other site
720554002307	H-loop/switch region; other site
720554002308	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
720554002309	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
720554002310	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
720554002311	Walker A/P-loop; other site
720554002312	ATP binding site [chemical binding]; other site
720554002313	Q-loop/lid; other site
720554002314	ABC transporter signature motif; other site
720554002315	Walker B; other site
720554002316	D-loop; other site
720554002317	H-loop/switch region; other site
720554002318	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
720554002319	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
720554002320	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
720554002321	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554002322	dimer interface [polypeptide binding]; other site
720554002323	conserved gate region; other site
720554002324	putative PBP binding loops; other site
720554002325	ABC-ATPase subunit interface; other site
720554002326	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
720554002327	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554002328	dimer interface [polypeptide binding]; other site
720554002329	conserved gate region; other site
720554002330	putative PBP binding loops; other site
720554002331	ABC-ATPase subunit interface; other site
720554002332	peroxiredoxin; Region: AhpC; TIGR03137
720554002333	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
720554002334	dimer interface [polypeptide binding]; other site
720554002335	decamer (pentamer of dimers) interface [polypeptide binding]; other site
720554002336	catalytic triad [active]
720554002337	peroxidatic and resolving cysteines [active]
720554002338	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
720554002339	active site
720554002340	HlyD family secretion protein; Region: HlyD; pfam00529
720554002341	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
720554002342	HlyD family secretion protein; Region: HlyD_3; pfam13437
720554002343	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002344	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002345	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002346	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554002347	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554002348	putative active site [active]
720554002349	putative NTP binding site [chemical binding]; other site
720554002350	putative nucleic acid binding site [nucleotide binding]; other site
720554002351	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554002352	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554002353	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554002354	Transposase; Region: HTH_Tnp_1; cl17663
720554002355	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554002356	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002357	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002358	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
720554002359	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
720554002360	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554002361	Coenzyme A binding pocket [chemical binding]; other site
720554002362	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
720554002363	putative metal binding site [ion binding]; other site
720554002364	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
720554002365	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002366	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554002367	putative transposase OrfB; Reviewed; Region: PHA02517
720554002368	HTH-like domain; Region: HTH_21; pfam13276
720554002369	Integrase core domain; Region: rve; pfam00665
720554002370	Integrase core domain; Region: rve_3; pfam13683
720554002371	Transposase; Region: HTH_Tnp_1; pfam01527
720554002372	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554002373	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
720554002374	Penicillinase repressor; Region: Pencillinase_R; pfam03965
720554002375	Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231
720554002376	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
720554002377	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
720554002378	Asp-box motif; other site
720554002379	Pyruvate formate lyase 1; Region: PFL1; cd01678
720554002380	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
720554002381	coenzyme A binding site [chemical binding]; other site
720554002382	active site
720554002383	catalytic residues [active]
720554002384	glycine loop; other site
720554002385	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
720554002386	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554002387	FeS/SAM binding site; other site
720554002388	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
720554002389	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
720554002390	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
720554002391	G1 box; other site
720554002392	GTP/Mg2+ binding site [chemical binding]; other site
720554002393	Switch I region; other site
720554002394	G2 box; other site
720554002395	G3 box; other site
720554002396	Switch II region; other site
720554002397	G4 box; other site
720554002398	G5 box; other site
720554002399	Nucleoside recognition; Region: Gate; pfam07670
720554002400	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
720554002401	Nucleoside recognition; Region: Gate; pfam07670
720554002402	zinc transporter ZupT; Provisional; Region: PRK04201
720554002403	ZIP Zinc transporter; Region: Zip; pfam02535
720554002404	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
720554002405	putative active site [active]
720554002406	Rubrerythrin [Energy production and conversion]; Region: COG1592
720554002407	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
720554002408	binuclear metal center [ion binding]; other site
720554002409	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
720554002410	iron binding site [ion binding]; other site
720554002411	AAA domain; Region: AAA_11; pfam13086
720554002412	Part of AAA domain; Region: AAA_19; pfam13245
720554002413	AAA domain; Region: AAA_12; pfam13087
720554002414	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
720554002415	catalytic site [active]
720554002416	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
720554002417	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554002418	hybrid cluster protein; Provisional; Region: PRK05290
720554002419	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554002420	ACS interaction site; other site
720554002421	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
720554002422	hybrid metal cluster; other site
720554002423	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554002424	Zn2+ binding site [ion binding]; other site
720554002425	Mg2+ binding site [ion binding]; other site
720554002426	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
720554002427	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
720554002428	active site
720554002429	FMN binding site [chemical binding]; other site
720554002430	putative catalytic residues [active]
720554002431	substrate binding site [chemical binding]; other site
720554002432	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
720554002433	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
720554002434	DNA interaction; other site
720554002435	Metal-binding active site; metal-binding site
720554002436	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002437	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002438	Carbohydrate Binding Module family 35 (CBM35), pectate lyase-like; appended mainly to enzymes that bind mannan (Man), xylan, glucuronic acid (GlcA) and possibly glucans; Region: CBM35_pectate_lyase-like; cd04082
720554002439	Ca binding site [ion binding]; other site
720554002440	Ca binding site (active) [ion binding]; other site
720554002441	ligand binding site [chemical binding]; other site
720554002442	putative pectinesterase; Region: PLN02432; cl01911
720554002443	Pectinesterase; Region: Pectinesterase; pfam01095
720554002444	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
720554002445	AAA domain; Region: AAA_30; pfam13604
720554002446	Family description; Region: UvrD_C_2; pfam13538
720554002447	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
720554002448	YmaF family; Region: YmaF; pfam12788
720554002449	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
720554002450	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
720554002451	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
720554002452	dimer interface [polypeptide binding]; other site
720554002453	active site
720554002454	metal binding site [ion binding]; metal-binding site
720554002455	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
720554002456	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
720554002457	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
720554002458	Alpha-glucuronidase [Carbohydrate transport and metabolism]; Region: AguA; COG3661
720554002459	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
720554002460	Glycosyl hydrolase family 67 C-terminus; Region: Glyco_hydro_67C; pfam07477
720554002461	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
720554002462	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554002463	dimer interface [polypeptide binding]; other site
720554002464	putative CheW interface [polypeptide binding]; other site
720554002465	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
720554002466	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
720554002467	ligand binding site [chemical binding]; other site
720554002468	Glucosyl transferase GtrII; Region: Glucos_trans_II; cl10304
720554002469	PAS domain S-box; Region: sensory_box; TIGR00229
720554002470	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554002471	putative active site [active]
720554002472	heme pocket [chemical binding]; other site
720554002473	PAS domain S-box; Region: sensory_box; TIGR00229
720554002474	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554002475	putative active site [active]
720554002476	heme pocket [chemical binding]; other site
720554002477	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554002478	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554002479	metal binding site [ion binding]; metal-binding site
720554002480	active site
720554002481	I-site; other site
720554002482	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
720554002483	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
720554002484	metal binding site 2 [ion binding]; metal-binding site
720554002485	putative DNA binding helix; other site
720554002486	metal binding site 1 [ion binding]; metal-binding site
720554002487	dimer interface [polypeptide binding]; other site
720554002488	structural Zn2+ binding site [ion binding]; other site
720554002489	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
720554002490	flavodoxin; Provisional; Region: PRK05568
720554002491	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
720554002492	Protein of unknown function (DUF3793); Region: DUF3793; pfam12672
720554002493	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
720554002494	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
720554002495	DNA interaction; other site
720554002496	Metal-binding active site; metal-binding site
720554002497	AMP-binding domain protein; Validated; Region: PRK08315
720554002498	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
720554002499	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
720554002500	acyl-activating enzyme (AAE) consensus motif; other site
720554002501	acyl-activating enzyme (AAE) consensus motif; other site
720554002502	putative AMP binding site [chemical binding]; other site
720554002503	putative active site [active]
720554002504	putative CoA binding site [chemical binding]; other site
720554002505	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
720554002506	dimer interface [polypeptide binding]; other site
720554002507	FMN binding site [chemical binding]; other site
720554002508	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554002509	MULE transposase domain; Region: MULE; pfam10551
720554002510	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
720554002511	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
720554002512	active site
720554002513	HIGH motif; other site
720554002514	nucleotide binding site [chemical binding]; other site
720554002515	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
720554002516	active site
720554002517	KMSKS motif; other site
720554002518	Protein of unknown function, DUF624; Region: DUF624; cl02369
720554002519	SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases; Region: XynE_like; cd01830
720554002520	active site
720554002521	catalytic triad [active]
720554002522	oxyanion hole [active]
720554002523	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554002524	Coenzyme A binding pocket [chemical binding]; other site
720554002525	Clostripain family; Region: Peptidase_C11; pfam03415
720554002526	TfoX C-terminal domain; Region: TfoX_C; pfam04994
720554002527	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
720554002528	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
720554002529	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
720554002530	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554002531	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
720554002532	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
720554002533	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554002534	motif II; other site
720554002535	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
720554002536	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
720554002537	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
720554002538	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
720554002539	FMN binding site [chemical binding]; other site
720554002540	active site
720554002541	catalytic residues [active]
720554002542	substrate binding site [chemical binding]; other site
720554002543	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
720554002544	DNA-binding site [nucleotide binding]; DNA binding site
720554002545	RNA-binding motif; other site
720554002546	Protein of unknown function (DUF1256); Region: DUF1256; cl06087
720554002547	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
720554002548	putative deacylase active site [active]
720554002549	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554002550	S-adenosylmethionine binding site [chemical binding]; other site
720554002551	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
720554002552	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
720554002553	putative active site [active]
720554002554	putative metal binding site [ion binding]; other site
720554002555	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
720554002556	AzlC protein; Region: AzlC; pfam03591
720554002557	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
720554002558	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
720554002559	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
720554002560	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
720554002561	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554002562	catalytic residue [active]
720554002563	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
720554002564	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
720554002565	substrate binding site [chemical binding]; other site
720554002566	active site
720554002567	catalytic residues [active]
720554002568	heterodimer interface [polypeptide binding]; other site
720554002569	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
720554002570	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554002571	non-specific DNA binding site [nucleotide binding]; other site
720554002572	salt bridge; other site
720554002573	sequence-specific DNA binding site [nucleotide binding]; other site
720554002574	AAA domain; Region: AAA_13; pfam13166
720554002575	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
720554002576	Domain of unknown function DUF21; Region: DUF21; pfam01595
720554002577	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
720554002578	Transporter associated domain; Region: CorC_HlyC; pfam03471
720554002579	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
720554002580	putative CheA interaction surface; other site
720554002581	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
720554002582	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554002583	dimerization interface [polypeptide binding]; other site
720554002584	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554002585	dimer interface [polypeptide binding]; other site
720554002586	putative CheW interface [polypeptide binding]; other site
720554002587	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: MutS; COG0249
720554002588	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554002589	Walker A/P-loop; other site
720554002590	ATP binding site [chemical binding]; other site
720554002591	Q-loop/lid; other site
720554002592	ABC transporter signature motif; other site
720554002593	Walker B; other site
720554002594	D-loop; other site
720554002595	H-loop/switch region; other site
720554002596	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: MutS; COG0249
720554002597	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554002598	Walker A/P-loop; other site
720554002599	ATP binding site [chemical binding]; other site
720554002600	Q-loop/lid; other site
720554002601	ABC transporter signature motif; other site
720554002602	Walker B; other site
720554002603	D-loop; other site
720554002604	H-loop/switch region; other site
720554002605	hydrogenase 4 subunit D; Validated; Region: PRK06525
720554002606	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
720554002607	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
720554002608	NADH dehydrogenase; Region: NADHdh; cl00469
720554002609	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
720554002610	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; pfam00329
720554002611	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
720554002612	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
720554002613	4Fe-4S binding domain; Region: Fer4; cl02805
720554002614	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
720554002615	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
720554002616	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
720554002617	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554002618	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554002619	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
720554002620	G4 box; other site
720554002621	G5 box; other site
720554002622	Acylphosphatase; Region: Acylphosphatase; pfam00708
720554002623	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
720554002624	HypF finger; Region: zf-HYPF; pfam07503
720554002625	HypF finger; Region: zf-HYPF; pfam07503
720554002626	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
720554002627	HupF/HypC family; Region: HupF_HypC; pfam01455
720554002628	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
720554002629	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
720554002630	dimerization interface [polypeptide binding]; other site
720554002631	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
720554002632	ATP binding site [chemical binding]; other site
720554002633	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
720554002634	nudix motif; other site
720554002635	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
720554002636	Isochorismatase family; Region: Isochorismatase; pfam00857
720554002637	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
720554002638	catalytic triad [active]
720554002639	conserved cis-peptide bond; other site
720554002640	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
720554002641	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
720554002642	active site
720554002643	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
720554002644	active site
720554002645	substrate-binding site [chemical binding]; other site
720554002646	metal-binding site [ion binding]
720554002647	GTP binding site [chemical binding]; other site
720554002648	transglutaminase; Provisional; Region: tgl; PRK03187
720554002649	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
720554002650	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
720554002651	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554002652	catalytic residue [active]
720554002653	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002654	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
720554002655	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
720554002656	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
720554002657	intersubunit interface [polypeptide binding]; other site
720554002658	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
720554002659	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
720554002660	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
720554002661	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
720554002662	ABC-ATPase subunit  interface; other site
720554002663	dimer interface [polypeptide binding]; other site
720554002664	putative PBP binding regions; other site
720554002665	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554002666	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554002667	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
720554002668	Leucine rich repeat; Region: LRR_8; pfam13855
720554002669	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554002670	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
720554002671	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554002672	Walker A/P-loop; other site
720554002673	ATP binding site [chemical binding]; other site
720554002674	Q-loop/lid; other site
720554002675	ABC transporter signature motif; other site
720554002676	Walker B; other site
720554002677	D-loop; other site
720554002678	H-loop/switch region; other site
720554002679	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
720554002680	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
720554002681	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554002682	Chain length determinant protein; Region: Wzz; cl15801
720554002683	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
720554002684	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
720554002685	NAD(P) binding site [chemical binding]; other site
720554002686	homodimer interface [polypeptide binding]; other site
720554002687	substrate binding site [chemical binding]; other site
720554002688	active site
720554002689	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
720554002690	classical (c) SDRs; Region: SDR_c; cd05233
720554002691	NAD(P) binding site [chemical binding]; other site
720554002692	active site
720554002693	Bacterial sugar transferase; Region: Bac_transf; pfam02397
720554002694	transketolase; Reviewed; Region: PRK05899
720554002695	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
720554002696	TPP-binding site [chemical binding]; other site
720554002697	dimer interface [polypeptide binding]; other site
720554002698	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
720554002699	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
720554002700	PYR/PP interface [polypeptide binding]; other site
720554002701	dimer interface [polypeptide binding]; other site
720554002702	TPP binding site [chemical binding]; other site
720554002703	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554002704	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
720554002705	active site
720554002706	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
720554002707	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
720554002708	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
720554002709	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
720554002710	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
720554002711	LicD family; Region: LicD; cl01378
720554002712	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
720554002713	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
720554002714	active site
720554002715	metal-binding site
720554002716	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
720554002717	Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719
720554002718	NAD(P) binding site [chemical binding]; other site
720554002719	homodimer interface [polypeptide binding]; other site
720554002720	substrate binding site [chemical binding]; other site
720554002721	active site
720554002722	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
720554002723	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
720554002724	inhibitor-cofactor binding pocket; inhibition site
720554002725	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554002726	catalytic residue [active]
720554002727	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
720554002728	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
720554002729	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
720554002730	catalytic residue [active]
720554002731	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554002732	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
720554002733	Coenzyme A binding pocket [chemical binding]; other site
720554002734	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
720554002735	active site
720554002736	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
720554002737	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
720554002738	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
720554002739	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554002740	NAD(P) binding site [chemical binding]; other site
720554002741	active site
720554002742	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
720554002743	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
720554002744	HIGH motif; other site
720554002745	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
720554002746	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
720554002747	active site
720554002748	KMSKS motif; other site
720554002749	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
720554002750	tRNA binding surface [nucleotide binding]; other site
720554002751	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
720554002752	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
720554002753	putative catalytic site [active]
720554002754	putative metal binding site [ion binding]; other site
720554002755	putative phosphate binding site [ion binding]; other site
720554002756	Rhomboid family; Region: Rhomboid; cl11446
720554002757	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
720554002758	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
720554002759	dimerization interface [polypeptide binding]; other site
720554002760	ligand binding site [chemical binding]; other site
720554002761	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554002762	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554002763	ATP binding site [chemical binding]; other site
720554002764	Mg2+ binding site [ion binding]; other site
720554002765	G-X-G motif; other site
720554002766	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554002767	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554002768	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554002769	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554002770	Walker A motif; other site
720554002771	ATP binding site [chemical binding]; other site
720554002772	Walker B motif; other site
720554002773	arginine finger; other site
720554002774	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
720554002775	Protein of unknown function DUF58; Region: DUF58; pfam01882
720554002776	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
720554002777	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554002778	non-specific DNA binding site [nucleotide binding]; other site
720554002779	salt bridge; other site
720554002780	sequence-specific DNA binding site [nucleotide binding]; other site
720554002781	desulfoferrodoxin; Region: dfx_rbo; TIGR00320
720554002782	Superoxide reductase-like (SORL) domain; present in a family of mononuclear non-heme iron proteins that includes superoxide reductase and desulfoferrodoxin. Superoxide reductase-like proteins scavenge superoxide anion radicals as a defense mechanism...; Region: SORL; cl00014
720554002783	non-heme iron binding site [ion binding]; other site
720554002784	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
720554002785	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
720554002786	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
720554002787	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
720554002788	Walker A/P-loop; other site
720554002789	ATP binding site [chemical binding]; other site
720554002790	Q-loop/lid; other site
720554002791	ABC transporter signature motif; other site
720554002792	Walker B; other site
720554002793	D-loop; other site
720554002794	H-loop/switch region; other site
720554002795	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
720554002796	NMT1/THI5 like; Region: NMT1; pfam09084
720554002797	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554002798	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554002799	dimer interface [polypeptide binding]; other site
720554002800	conserved gate region; other site
720554002801	putative PBP binding loops; other site
720554002802	ABC-ATPase subunit interface; other site
720554002803	Domain of unknown function DUF77; Region: DUF77; pfam01910
720554002804	S-layer homology domain; Region: SLH; pfam00395
720554002805	S-layer homology domain; Region: SLH; pfam00395
720554002806	S-layer homology domain; Region: SLH; pfam00395
720554002807	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
720554002808	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
720554002809	putative catalytic cysteine [active]
720554002810	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002811	Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: IleS; COG0060
720554002812	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
720554002813	HIGH motif; other site
720554002814	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
720554002815	active site
720554002816	KMSKS motif; other site
720554002817	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
720554002818	tRNA binding surface [nucleotide binding]; other site
720554002819	anticodon binding site; other site
720554002820	prolyl-tRNA synthetase; Provisional; Region: PRK08661
720554002821	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
720554002822	dimer interface [polypeptide binding]; other site
720554002823	motif 1; other site
720554002824	active site
720554002825	motif 2; other site
720554002826	motif 3; other site
720554002827	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
720554002828	anticodon binding site; other site
720554002829	zinc-binding site [ion binding]; other site
720554002830	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
720554002831	putative active site [active]
720554002832	putative metal binding residues [ion binding]; other site
720554002833	signature motif; other site
720554002834	putative dimer interface [polypeptide binding]; other site
720554002835	putative phosphate binding site [ion binding]; other site
720554002836	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002837	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
720554002838	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554002839	Cellulose binding domain; Region: CBM_3; pfam00942
720554002840	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554002841	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554002842	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
720554002843	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002844	endoglucanase; Region: PLN02420
720554002845	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554002846	Cellulose binding domain; Region: CBM_3; pfam00942
720554002847	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002848	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
720554002849	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
720554002850	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
720554002851	peroxiredoxin; Provisional; Region: PRK13189
720554002852	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
720554002853	dimer interface [polypeptide binding]; other site
720554002854	decamer (pentamer of dimers) interface [polypeptide binding]; other site
720554002855	catalytic triad [active]
720554002856	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554002857	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554002858	active site
720554002859	phosphorylation site [posttranslational modification]
720554002860	intermolecular recognition site; other site
720554002861	dimerization interface [polypeptide binding]; other site
720554002862	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554002863	DNA binding site [nucleotide binding]
720554002864	Lamin Tail Domain; Region: LTD; pfam00932
720554002865	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
720554002866	CotH protein; Region: CotH; pfam08757
720554002867	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554002868	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
720554002869	putative metal binding residues [ion binding]; other site
720554002870	signature motif; other site
720554002871	dimer interface [polypeptide binding]; other site
720554002872	active site
720554002873	polyP binding site; other site
720554002874	substrate binding site [chemical binding]; other site
720554002875	acceptor-phosphate pocket; other site
720554002876	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
720554002877	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
720554002878	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
720554002879	putative ligand binding site [chemical binding]; other site
720554002880	putative NAD binding site [chemical binding]; other site
720554002881	catalytic site [active]
720554002882	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
720554002883	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554002884	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
720554002885	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
720554002886	active site
720554002887	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554002888	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554002889	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554002890	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554002891	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
720554002892	Putative zinc-finger; Region: zf-HC2; pfam13490
720554002893	Bacterial Ig-like domain; Region: Big_5; pfam13205
720554002894	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
720554002895	Alpha-2-macroglobulin family; Region: A2M; pfam00207
720554002896	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
720554002897	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554002898	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554002899	DNA binding residues [nucleotide binding]
720554002900	glycogen synthase; Provisional; Region: glgA; PRK00654
720554002901	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
720554002902	ADP-binding pocket [chemical binding]; other site
720554002903	homodimer interface [polypeptide binding]; other site
720554002904	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
720554002905	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
720554002906	active site
720554002907	catalytic tetrad [active]
720554002908	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554002909	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554002910	Walker A motif; other site
720554002911	ATP binding site [chemical binding]; other site
720554002912	Walker B motif; other site
720554002913	arginine finger; other site
720554002914	isocitrate dehydrogenase; Validated; Region: PRK08299
720554002915	tRNA pseudouridine synthase A; Reviewed; Region: PRK12434
720554002916	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
720554002917	dimerization interface 3.5A [polypeptide binding]; other site
720554002918	active site
720554002919	hypothetical protein; Provisional; Region: PRK05590
720554002920	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
720554002921	Sulfatase; Region: Sulfatase; pfam00884
720554002922	Rubrerythrin [Energy production and conversion]; Region: COG1592
720554002923	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
720554002924	iron binding site [ion binding]; other site
720554002925	Protein of unknown function DUF45; Region: DUF45; pfam01863
720554002926	Sporulation protein YtrH; Region: Spore_YtrH; pfam14034
720554002927	DNA gyrase/topoisomerase IV, subunit A; Region: DNA_topoisoIV; pfam00521
720554002928	Predicted membrane protein (DUF2142); Region: DUF2142; pfam09913
720554002929	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
720554002930	active site
720554002931	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
720554002932	dimer interface [polypeptide binding]; other site
720554002933	active site
720554002934	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
720554002935	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
720554002936	putative dimer interface [polypeptide binding]; other site
720554002937	putative anticodon binding site; other site
720554002938	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
720554002939	homodimer interface [polypeptide binding]; other site
720554002940	motif 1; other site
720554002941	motif 2; other site
720554002942	active site
720554002943	motif 3; other site
720554002944	pyruvate kinase; Provisional; Region: PRK06354
720554002945	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
720554002946	domain interfaces; other site
720554002947	active site
720554002948	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
720554002949	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
720554002950	active site
720554002951	putative catalytic site [active]
720554002952	DNA binding site [nucleotide binding]
720554002953	putative phosphate binding site [ion binding]; other site
720554002954	metal binding site A [ion binding]; metal-binding site
720554002955	AP binding site [nucleotide binding]; other site
720554002956	metal binding site B [ion binding]; metal-binding site
720554002957	excinuclease ABC subunit C; Provisional; Region: uvrC; PRK14669
720554002958	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
720554002959	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
720554002960	spermidine/putrescine ABC transporter ATP-binding subunit; Region: potA; TIGR01187
720554002961	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554002962	PAS fold; Region: PAS_3; pfam08447
720554002963	putative active site [active]
720554002964	heme pocket [chemical binding]; other site
720554002965	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554002966	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554002967	dimer interface [polypeptide binding]; other site
720554002968	phosphorylation site [posttranslational modification]
720554002969	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554002970	ATP binding site [chemical binding]; other site
720554002971	Mg2+ binding site [ion binding]; other site
720554002972	G-X-G motif; other site
720554002973	Response regulator receiver domain; Region: Response_reg; pfam00072
720554002974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554002975	active site
720554002976	phosphorylation site [posttranslational modification]
720554002977	intermolecular recognition site; other site
720554002978	dimerization interface [polypeptide binding]; other site
720554002979	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
720554002980	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554002981	ATP binding site [chemical binding]; other site
720554002982	G-X-G motif; other site
720554002983	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
720554002984	YtxH-like protein; Region: YtxH; pfam12732
720554002985	Probable zinc-binding domain; Region: zf-trcl; pfam13451
720554002986	Putative amidase domain; Region: Amidase_6; pfam12671
720554002987	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
720554002988	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
720554002989	heterotetramer interface [polypeptide binding]; other site
720554002990	active site pocket [active]
720554002991	cleavage site
720554002992	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
720554002993	Found in ATP-dependent protease La (LON); Region: LON; smart00464
720554002994	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554002995	Walker A motif; other site
720554002996	ATP binding site [chemical binding]; other site
720554002997	Walker B motif; other site
720554002998	arginine finger; other site
720554002999	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
720554003000	PRC-barrel domain containing protein [General function prediction only]; Region: COG3881
720554003001	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
720554003002	VanW like protein; Region: VanW; pfam04294
720554003003	G5 domain; Region: G5; pfam07501
720554003004	Negative regulator of genetic competence (MecA); Region: MecA; cl02022
720554003005	putative minor structural protein; Region: PHA01351
720554003006	Maf-like protein; Reviewed; Region: PRK00078
720554003007	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
720554003008	active site
720554003009	dimer interface [polypeptide binding]; other site
720554003010	rod shape-determining protein MreB; Provisional; Region: PRK13927
720554003011	MreB and similar proteins; Region: MreB_like; cd10225
720554003012	nucleotide binding site [chemical binding]; other site
720554003013	Mg binding site [ion binding]; other site
720554003014	putative protofilament interaction site [polypeptide binding]; other site
720554003015	RodZ interaction site [polypeptide binding]; other site
720554003016	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
720554003017	rod shape-determining protein MreC; Region: MreC; pfam04085
720554003018	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
720554003019	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
720554003020	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
720554003021	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
720554003022	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
720554003023	septum formation inhibitor; Reviewed; Region: minC; PRK00513
720554003024	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
720554003025	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
720554003026	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
720554003027	Switch I; other site
720554003028	Switch II; other site
720554003029	cell division topological specificity factor MinE; Provisional; Region: PRK13987
720554003030	methylglyoxal synthase; Validated; Region: mgsA; PRK05234
720554003031	substrate binding site [chemical binding]; other site
720554003032	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
720554003033	Peptidase family M23; Region: Peptidase_M23; pfam01551
720554003034	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
720554003035	active site
720554003036	putative substrate binding region [chemical binding]; other site
720554003037	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
720554003038	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
720554003039	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554003040	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
720554003041	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
720554003042	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
720554003043	catalytic motif [active]
720554003044	Zn binding site [ion binding]; other site
720554003045	RibD C-terminal domain; Region: RibD_C; cl17279
720554003046	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
720554003047	Lumazine binding domain; Region: Lum_binding; pfam00677
720554003048	Lumazine binding domain; Region: Lum_binding; pfam00677
720554003049	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
720554003050	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
720554003051	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
720554003052	dimerization interface [polypeptide binding]; other site
720554003053	active site
720554003054	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
720554003055	homopentamer interface [polypeptide binding]; other site
720554003056	active site
720554003057	PilZ domain; Region: PilZ; pfam07238
720554003058	HPr kinase/phosphorylase; Provisional; Region: PRK05428
720554003059	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
720554003060	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
720554003061	Hpr binding site; other site
720554003062	active site
720554003063	homohexamer subunit interaction site [polypeptide binding]; other site
720554003064	putative hydrolase; Validated; Region: PRK09248
720554003065	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
720554003066	active site
720554003067	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
720554003068	FAD binding domain; Region: FAD_binding_4; pfam01565
720554003069	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
720554003070	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
720554003071	shikimate kinase; Provisional; Region: PRK13947
720554003072	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
720554003073	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
720554003074	phosphate binding site [ion binding]; other site
720554003075	putative substrate binding pocket [chemical binding]; other site
720554003076	dimer interface [polypeptide binding]; other site
720554003077	Glycogen debranching enzyme N terminal; Region: GDE_N; pfam12439
720554003078	glycogen debranching enzyme, archaeal type, putative; Region: gde_arch; TIGR01561
720554003079	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
720554003080	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
720554003081	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
720554003082	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
720554003083	dimerization domain swap beta strand [polypeptide binding]; other site
720554003084	regulatory protein interface [polypeptide binding]; other site
720554003085	active site
720554003086	regulatory phosphorylation site [posttranslational modification]; other site
720554003087	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
720554003088	anti sigma factor interaction site; other site
720554003089	regulatory phosphorylation site [posttranslational modification]; other site
720554003090	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
720554003091	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554003092	ATP binding site [chemical binding]; other site
720554003093	Mg2+ binding site [ion binding]; other site
720554003094	G-X-G motif; other site
720554003095	sporulation sigma factor SigF; Validated; Region: PRK05572
720554003096	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554003097	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
720554003098	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554003099	DNA binding residues [nucleotide binding]
720554003100	SpoVA protein; Region: SpoVA; cl04298
720554003101	stage V sporulation protein AD; Validated; Region: PRK08304
720554003102	stage V sporulation protein AD; Provisional; Region: PRK12404
720554003103	SpoVA protein; Region: SpoVA; cl04298
720554003104	Stage V sporulation protein AE1; Region: SpoVAE; pfam14097
720554003105	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
720554003106	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
720554003107	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
720554003108	M20 Peptidase T like enzymes specifically cleave tripeptides; Region: M20_peptT_like; cd05683
720554003109	peptidase T-like protein; Region: PepT-like; TIGR01883
720554003110	metal binding site [ion binding]; metal-binding site
720554003111	putative dimer interface [polypeptide binding]; other site
720554003112	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
720554003113	phosphofructokinase; Region: PFK_mixed; TIGR02483
720554003114	active site
720554003115	ADP/pyrophosphate binding site [chemical binding]; other site
720554003116	dimerization interface [polypeptide binding]; other site
720554003117	allosteric effector site; other site
720554003118	fructose-1,6-bisphosphate binding site; other site
720554003119	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
720554003120	glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PTZ00023
720554003121	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
720554003122	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
720554003123	Phosphoglycerate kinase; Region: PGK; pfam00162
720554003124	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
720554003125	substrate binding site [chemical binding]; other site
720554003126	hinge regions; other site
720554003127	ADP binding site [chemical binding]; other site
720554003128	catalytic site [active]
720554003129	triosephosphate isomerase; Provisional; Region: PRK14565
720554003130	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
720554003131	substrate binding site [chemical binding]; other site
720554003132	dimer interface [polypeptide binding]; other site
720554003133	catalytic triad [active]
720554003134	phosphoglyceromutase; Provisional; Region: PRK05434
720554003135	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
720554003136	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
720554003137	sugar binding site [chemical binding]; other site
720554003138	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
720554003139	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554003140	RHS Repeat; Region: RHS_repeat; pfam05593
720554003141	RHS Repeat; Region: RHS_repeat; pfam05593
720554003142	RHS Repeat; Region: RHS_repeat; pfam05593
720554003143	RHS Repeat; Region: RHS_repeat; pfam05593
720554003144	RHS Repeat; Region: RHS_repeat; pfam05593
720554003145	RHS Repeat; Region: RHS_repeat; cl11982
720554003146	RHS Repeat; Region: RHS_repeat; pfam05593
720554003147	RHS Repeat; Region: RHS_repeat; pfam05593
720554003148	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554003149	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554003150	protein-splicing catalytic site; other site
720554003151	thioester formation/cholesterol transfer; other site
720554003152	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554003153	Protein of unknown function (DUF2433); Region: DUF2433; pfam10360
720554003154	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554003155	MULE transposase domain; Region: MULE; pfam10551
720554003156	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554003157	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
720554003158	Uncharacterized conserved protein [Function unknown]; Region: COG2006
720554003159	Domain of unknown function (DUF362); Region: DUF362; pfam04015
720554003160	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
720554003161	Cellulose binding domain; Region: CBM_3; pfam00942
720554003162	enolase; Provisional; Region: eno; PRK00077
720554003163	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
720554003164	dimer interface [polypeptide binding]; other site
720554003165	metal binding site [ion binding]; metal-binding site
720554003166	substrate binding pocket [chemical binding]; other site
720554003167	Preprotein translocase SecG subunit; Region: SecG; pfam03840
720554003168	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554003169	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554003170	Zn2+ binding site [ion binding]; other site
720554003171	Mg2+ binding site [ion binding]; other site
720554003172	ribonuclease R; Region: RNase_R; TIGR02063
720554003173	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
720554003174	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
720554003175	RNB domain; Region: RNB; pfam00773
720554003176	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
720554003177	RNA binding site [nucleotide binding]; other site
720554003178	Uncharacterized conserved protein [Function unknown]; Region: COG1683
720554003179	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
720554003180	regulatory protein interface [polypeptide binding]; other site
720554003181	regulatory phosphorylation site [posttranslational modification]; other site
720554003182	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
720554003183	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
720554003184	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554003185	FeS/SAM binding site; other site
720554003186	hypothetical protein; Provisional; Region: PRK05473
720554003187	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
720554003188	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
720554003189	active site
720554003190	catalytic tetrad [active]
720554003191	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
720554003192	Protein of unknown function (DUF3048); Region: DUF3048; pfam11258
720554003193	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
720554003194	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
720554003195	B12 binding site [chemical binding]; other site
720554003196	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554003197	FeS/SAM binding site; other site
720554003198	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
720554003199	Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; pfam10105
720554003200	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
720554003201	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
720554003202	homodimer interface [polypeptide binding]; other site
720554003203	oligonucleotide binding site [chemical binding]; other site
720554003204	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
720554003205	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
720554003206	Protein of unknown function (DUF464); Region: DUF464; pfam04327
720554003207	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
720554003208	GTPase CgtA; Reviewed; Region: obgE; PRK12297
720554003209	GTP1/OBG; Region: GTP1_OBG; pfam01018
720554003210	Obg GTPase; Region: Obg; cd01898
720554003211	G1 box; other site
720554003212	GTP/Mg2+ binding site [chemical binding]; other site
720554003213	Switch I region; other site
720554003214	G2 box; other site
720554003215	G3 box; other site
720554003216	Switch II region; other site
720554003217	G4 box; other site
720554003218	G5 box; other site
720554003219	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
720554003220	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
720554003221	Domain of unknown function (DUF4364); Region: DUF4364; pfam14277
720554003222	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
720554003223	Response regulator receiver domain; Region: Response_reg; pfam00072
720554003224	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554003225	active site
720554003226	phosphorylation site [posttranslational modification]
720554003227	intermolecular recognition site; other site
720554003228	dimerization interface [polypeptide binding]; other site
720554003229	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
720554003230	Sulfatase; Region: Sulfatase; pfam00884
720554003231	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
720554003232	Putative catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases which consist of a 5-stranded beta/alpha barrel; Region: CE4_DAC_u3_5s; cd10972
720554003233	putative active site [active]
720554003234	putative metal binding site [ion binding]; other site
720554003235	argininosuccinate lyase; Provisional; Region: PRK00855
720554003236	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
720554003237	active sites [active]
720554003238	tetramer interface [polypeptide binding]; other site
720554003239	argininosuccinate synthase; Provisional; Region: PRK13820
720554003240	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
720554003241	ANP binding site [chemical binding]; other site
720554003242	Substrate Binding Site II [chemical binding]; other site
720554003243	Substrate Binding Site I [chemical binding]; other site
720554003244	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
720554003245	active site
720554003246	putative DNA-binding cleft [nucleotide binding]; other site
720554003247	dimer interface [polypeptide binding]; other site
720554003248	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
720554003249	RuvA N terminal domain; Region: RuvA_N; pfam01330
720554003250	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
720554003251	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
720554003252	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554003253	Walker A motif; other site
720554003254	ATP binding site [chemical binding]; other site
720554003255	Walker B motif; other site
720554003256	arginine finger; other site
720554003257	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
720554003258	type IV pilus assembly protein PilM; Region: pilM; TIGR01175
720554003259	Cell division protein FtsA; Region: FtsA; cl17206
720554003260	Cell division protein FtsA; Region: FtsA; pfam14450
720554003261	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554003262	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554003263	AMIN domain; Region: AMIN; pfam11741
720554003264	AMIN domain; Region: AMIN; pfam11741
720554003265	AMIN domain; Region: AMIN; pfam11741
720554003266	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
720554003267	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
720554003268	active site
720554003269	metal binding site [ion binding]; metal-binding site
720554003270	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
720554003271	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
720554003272	NAD binding site [chemical binding]; other site
720554003273	homodimer interface [polypeptide binding]; other site
720554003274	active site
720554003275	substrate binding site [chemical binding]; other site
720554003276	Sporulation and spore germination; Region: Germane; pfam10646
720554003277	Sporulation and spore germination; Region: Germane; pfam10646
720554003278	ribonuclease PH; Reviewed; Region: rph; PRK00173
720554003279	Ribonuclease PH; Region: RNase_PH_bact; cd11362
720554003280	hexamer interface [polypeptide binding]; other site
720554003281	active site
720554003282	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
720554003283	active site
720554003284	dimerization interface [polypeptide binding]; other site
720554003285	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
720554003286	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
720554003287	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
720554003288	Family description; Region: UvrD_C_2; pfam13538
720554003289	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
720554003290	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
720554003291	DHH family; Region: DHH; pfam01368
720554003292	DHHA1 domain; Region: DHHA1; pfam02272
720554003293	Protein phosphatase 2C; Region: PP2C; pfam00481
720554003294	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
720554003295	active site
720554003296	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
720554003297	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
720554003298	active site
720554003299	ATP binding site [chemical binding]; other site
720554003300	substrate binding site [chemical binding]; other site
720554003301	activation loop (A-loop); other site
720554003302	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
720554003303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554003304	dimer interface [polypeptide binding]; other site
720554003305	conserved gate region; other site
720554003306	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
720554003307	ABC-ATPase subunit interface; other site
720554003308	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
720554003309	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554003310	ABC-ATPase subunit interface; other site
720554003311	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
720554003312	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
720554003313	SEC-C motif; Region: SEC-C; pfam02810
720554003314	FeoA domain; Region: FeoA; pfam04023
720554003315	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
720554003316	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554003317	NAD(P) binding site [chemical binding]; other site
720554003318	active site
720554003319	Transposase domain (DUF772); Region: DUF772; pfam05598
720554003320	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554003321	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554003322	PAS domain; Region: PAS_9; pfam13426
720554003323	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
720554003324	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
720554003325	dinuclear metal binding motif [ion binding]; other site
720554003326	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
720554003327	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
720554003328	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554003329	TPR motif; other site
720554003330	binding surface
720554003331	Ribulose bisphosphate carboxylase like proteins (RLPs) similar to R.rubrum RLP; Region: RLP_RrRLP; cd08210
720554003332	dimer interface [polypeptide binding]; other site
720554003333	active site
720554003334	catalytic residue [active]
720554003335	metal binding site [ion binding]; metal-binding site
720554003336	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
720554003337	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
720554003338	PYR/PP interface [polypeptide binding]; other site
720554003339	dimer interface [polypeptide binding]; other site
720554003340	TPP binding site [chemical binding]; other site
720554003341	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554003342	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
720554003343	TPP-binding site [chemical binding]; other site
720554003344	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
720554003345	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
720554003346	HIGH motif; other site
720554003347	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
720554003348	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
720554003349	active site
720554003350	KMSKS motif; other site
720554003351	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
720554003352	tRNA binding surface [nucleotide binding]; other site
720554003353	anticodon binding site; other site
720554003354	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
720554003355	ANTAR domain; Region: ANTAR; pfam03861
720554003356	nitrogenase reductase; Reviewed; Region: nifH; PRK13235
720554003357	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
720554003358	Nucleotide-binding sites [chemical binding]; other site
720554003359	Walker A motif; other site
720554003360	Switch I region of nucleotide binding site; other site
720554003361	Fe4S4 binding sites [ion binding]; other site
720554003362	Switch II region of nucleotide binding site; other site
720554003363	Nitrogen regulatory protein P-II; Region: P-II; pfam00543
720554003364	Nitrogen regulatory protein P-II; Region: P-II; smart00938
720554003365	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
720554003366	Nitrogen regulatory protein P-II; Region: P-II; smart00938
720554003367	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554003368	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554003369	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554003370	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554003371	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554003372	nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Region: nifE; TIGR01283
720554003373	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554003374	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554003375	nitrogenase cofactor biosynthesis protein NifB; Region: nifB; TIGR01290
720554003376	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554003377	FeS/SAM binding site; other site
720554003378	NifB belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme as part of...; Region: NifB; cd00852
720554003379	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
720554003380	dimer interface [polypeptide binding]; other site
720554003381	[2Fe-2S] cluster binding site [ion binding]; other site
720554003382	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
720554003383	active site
720554003384	Streptomyces rubellomurinus FrbC and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_NifV; cd07939
720554003385	active site
720554003386	catalytic residues [active]
720554003387	metal binding site [ion binding]; metal-binding site
720554003388	NAD synthetase; Reviewed; Region: nadE; PRK02628
720554003389	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
720554003390	multimer interface [polypeptide binding]; other site
720554003391	active site
720554003392	catalytic triad [active]
720554003393	protein interface 1 [polypeptide binding]; other site
720554003394	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
720554003395	homodimer interface [polypeptide binding]; other site
720554003396	NAD binding pocket [chemical binding]; other site
720554003397	ATP binding pocket [chemical binding]; other site
720554003398	Mg binding site [ion binding]; other site
720554003399	active-site loop [active]
720554003400	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554003401	MULE transposase domain; Region: MULE; pfam10551
720554003402	transposase; Provisional; Region: PRK06526
720554003403	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554003404	Walker A motif; other site
720554003405	ATP binding site [chemical binding]; other site
720554003406	Walker B motif; other site
720554003407	arginine finger; other site
720554003408	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554003409	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554003410	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554003411	Walker A/P-loop; other site
720554003412	ATP binding site [chemical binding]; other site
720554003413	Q-loop/lid; other site
720554003414	ABC transporter signature motif; other site
720554003415	Walker B; other site
720554003416	D-loop; other site
720554003417	H-loop/switch region; other site
720554003418	Hemerythrin; Region: Hemerythrin; cd12107
720554003419	Fe binding site [ion binding]; other site
720554003420	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554003421	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554003422	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554003423	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554003424	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
720554003425	NMT1/THI5 like; Region: NMT1; pfam09084
720554003426	substrate binding pocket [chemical binding]; other site
720554003427	membrane-bound complex binding site; other site
720554003428	hinge residues; other site
720554003429	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554003430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554003431	dimer interface [polypeptide binding]; other site
720554003432	conserved gate region; other site
720554003433	putative PBP binding loops; other site
720554003434	ABC-ATPase subunit interface; other site
720554003435	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
720554003436	Sulfatase; Region: Sulfatase; cl17466
720554003437	coproporphyrinogen III oxidase; Validated; Region: PRK08208
720554003438	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554003439	FeS/SAM binding site; other site
720554003440	HemN C-terminal domain; Region: HemN_C; pfam06969
720554003441	phosphoglycolate phosphatase; Provisional; Region: PRK01158
720554003442	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554003443	active site
720554003444	motif I; other site
720554003445	motif II; other site
720554003446	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554003447	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554003448	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554003449	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
720554003450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554003451	active site
720554003452	phosphorylation site [posttranslational modification]
720554003453	intermolecular recognition site; other site
720554003454	dimerization interface [polypeptide binding]; other site
720554003455	LytTr DNA-binding domain; Region: LytTR; smart00850
720554003456	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
720554003457	active site
720554003458	catalytic residues [active]
720554003459	S-layer homology domain; Region: SLH; pfam00395
720554003460	S-layer homology domain; Region: SLH; pfam00395
720554003461	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554003462	Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism]; Region: COG4305
720554003463	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
720554003464	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
720554003465	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554003466	dimer interface [polypeptide binding]; other site
720554003467	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
720554003468	conserved gate region; other site
720554003469	putative PBP binding loops; other site
720554003470	ABC-ATPase subunit interface; other site
720554003471	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
720554003472	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554003473	Walker A/P-loop; other site
720554003474	ATP binding site [chemical binding]; other site
720554003475	Q-loop/lid; other site
720554003476	ABC transporter signature motif; other site
720554003477	Walker B; other site
720554003478	D-loop; other site
720554003479	H-loop/switch region; other site
720554003480	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
720554003481	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
720554003482	G1 box; other site
720554003483	putative GEF interaction site [polypeptide binding]; other site
720554003484	GTP/Mg2+ binding site [chemical binding]; other site
720554003485	Switch I region; other site
720554003486	G2 box; other site
720554003487	G3 box; other site
720554003488	Switch II region; other site
720554003489	G4 box; other site
720554003490	G5 box; other site
720554003491	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
720554003492	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
720554003493	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
720554003494	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
720554003495	active site
720554003496	DRTGG domain; Region: DRTGG; pfam07085
720554003497	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
720554003498	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554003499	ATP binding site [chemical binding]; other site
720554003500	Mg2+ binding site [ion binding]; other site
720554003501	G-X-G motif; other site
720554003502	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
720554003503	4Fe-4S binding domain; Region: Fer4; pfam00037
720554003504	4Fe-4S binding domain; Region: Fer4_6; pfam12837
720554003505	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
720554003506	Putative Fe-S cluster; Region: FeS; cl17515
720554003507	DRTGG domain; Region: DRTGG; pfam07085
720554003508	PHP domain; Region: PHP; pfam02811
720554003509	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432
720554003510	active site
720554003511	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432
720554003512	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
720554003513	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
720554003514	putative dimer interface [polypeptide binding]; other site
720554003515	[2Fe-2S] cluster binding site [ion binding]; other site
720554003516	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554003517	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554003518	ATP binding site [chemical binding]; other site
720554003519	Mg2+ binding site [ion binding]; other site
720554003520	G-X-G motif; other site
720554003521	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
720554003522	dimer interface [polypeptide binding]; other site
720554003523	[2Fe-2S] cluster binding site [ion binding]; other site
720554003524	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
720554003525	dimer interface [polypeptide binding]; other site
720554003526	[2Fe-2S] cluster binding site [ion binding]; other site
720554003527	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
720554003528	SLBB domain; Region: SLBB; pfam10531
720554003529	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
720554003530	4Fe-4S binding domain; Region: Fer4; pfam00037
720554003531	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
720554003532	4Fe-4S binding domain; Region: Fer4; pfam00037
720554003533	bidirectional hydrogenase complex protein HoxU; Validated; Region: PRK07569
720554003534	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
720554003535	catalytic loop [active]
720554003536	iron binding site [ion binding]; other site
720554003537	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
720554003538	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
720554003539	4Fe-4S binding domain; Region: Fer4; pfam00037
720554003540	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
720554003541	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
720554003542	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
720554003543	active site
720554003544	8-oxo-dGMP binding site [chemical binding]; other site
720554003545	nudix motif; other site
720554003546	metal binding site [ion binding]; metal-binding site
720554003547	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
720554003548	putative FMN binding site [chemical binding]; other site
720554003549	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
720554003550	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554003551	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554003552	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554003553	LL-diaminopimelate aminotransferase; Provisional; Region: PRK09276
720554003554	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554003555	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554003556	homodimer interface [polypeptide binding]; other site
720554003557	catalytic residue [active]
720554003558	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
720554003559	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
720554003560	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
720554003561	dimer interface [polypeptide binding]; other site
720554003562	motif 1; other site
720554003563	active site
720554003564	motif 2; other site
720554003565	motif 3; other site
720554003566	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
720554003567	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
720554003568	putative tRNA-binding site [nucleotide binding]; other site
720554003569	B3/4 domain; Region: B3_4; pfam03483
720554003570	tRNA synthetase B5 domain; Region: B5; smart00874
720554003571	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
720554003572	dimer interface [polypeptide binding]; other site
720554003573	motif 1; other site
720554003574	motif 3; other site
720554003575	motif 2; other site
720554003576	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
720554003577	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
720554003578	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
720554003579	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
720554003580	active site
720554003581	dimer interface [polypeptide binding]; other site
720554003582	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
720554003583	dimer interface [polypeptide binding]; other site
720554003584	active site
720554003585	phosphodiesterase YaeI; Provisional; Region: PRK11340
720554003586	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
720554003587	putative active site [active]
720554003588	putative metal binding site [ion binding]; other site
720554003589	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554003590	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554003591	dimer interface [polypeptide binding]; other site
720554003592	putative CheW interface [polypeptide binding]; other site
720554003593	Predicted glycosylase [Carbohydrate transport and metabolism]; Region: COG2152
720554003594	Domain of unknown function (DUF377); Region: DUF377; pfam04041
720554003595	active site
720554003596	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
720554003597	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
720554003598	active site
720554003599	Substrate binding site; other site
720554003600	Mg++ binding site; other site
720554003601	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
720554003602	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
720554003603	putative trimer interface [polypeptide binding]; other site
720554003604	putative CoA binding site [chemical binding]; other site
720554003605	This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides; Region: GT1_ecORF704_like; cd03822
720554003606	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554003607	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
720554003608	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
720554003609	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
720554003610	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
720554003611	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
720554003612	5S rRNA interface [nucleotide binding]; other site
720554003613	CTC domain interface [polypeptide binding]; other site
720554003614	L16 interface [polypeptide binding]; other site
720554003615	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07666
720554003616	classical (c) SDRs; Region: SDR_c; cd05233
720554003617	NAD(P) binding site [chemical binding]; other site
720554003618	active site
720554003619	HTH domain; Region: HTH_11; pfam08279
720554003620	WYL domain; Region: WYL; pfam13280
720554003621	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554003622	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554003623	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554003624	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
720554003625	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554003626	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554003627	DNA binding residues [nucleotide binding]
720554003628	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
720554003629	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554003630	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
720554003631	active site
720554003632	motif I; other site
720554003633	motif II; other site
720554003634	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
720554003635	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
720554003636	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
720554003637	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554003638	PilZ domain; Region: PilZ; pfam07238
720554003639	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
720554003640	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554003641	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
720554003642	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
720554003643	dimer interface [polypeptide binding]; other site
720554003644	PYR/PP interface [polypeptide binding]; other site
720554003645	TPP binding site [chemical binding]; other site
720554003646	substrate binding site [chemical binding]; other site
720554003647	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554003648	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
720554003649	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
720554003650	TPP-binding site [chemical binding]; other site
720554003651	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
720554003652	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
720554003653	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
720554003654	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
720554003655	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
720554003656	YmaF family; Region: YmaF; pfam12788
720554003657	Transcriptional regulator [Transcription]; Region: LytR; COG1316
720554003658	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
720554003659	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554003660	active site
720554003661	phosphorylation site [posttranslational modification]
720554003662	intermolecular recognition site; other site
720554003663	dimerization interface [polypeptide binding]; other site
720554003664	LytTr DNA-binding domain; Region: LytTR; smart00850
720554003665	hypothetical protein; Provisional; Region: PRK13665
720554003666	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
720554003667	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
720554003668	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554003669	ATP binding site [chemical binding]; other site
720554003670	Mg2+ binding site [ion binding]; other site
720554003671	G-X-G motif; other site
720554003672	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
720554003673	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
720554003674	homodimer interface [polypeptide binding]; other site
720554003675	substrate-cofactor binding pocket; other site
720554003676	catalytic residue [active]
720554003677	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
720554003678	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554003679	active site
720554003680	motif I; other site
720554003681	motif II; other site
720554003682	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
720554003683	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
720554003684	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
720554003685	shikimate binding site; other site
720554003686	NAD(P) binding site [chemical binding]; other site
720554003687	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
720554003688	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
720554003689	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
720554003690	Late competence development protein ComFB; Region: ComFB; pfam10719
720554003691	AP endonuclease family 2; Region: AP2Ec; smart00518
720554003692	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
720554003693	Metal-binding active site; metal-binding site
720554003694	AP (apurinic/apyrimidinic) site pocket; other site
720554003695	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
720554003696	Dehydroquinase class II; Region: DHquinase_II; pfam01220
720554003697	active site
720554003698	trimer interface [polypeptide binding]; other site
720554003699	dimer interface [polypeptide binding]; other site
720554003700	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
720554003701	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
720554003702	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
720554003703	active site
720554003704	elongation factor P; Validated; Region: PRK00529
720554003705	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
720554003706	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
720554003707	RNA binding site [nucleotide binding]; other site
720554003708	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
720554003709	RNA binding site [nucleotide binding]; other site
720554003710	probable DNA metabolism protein; Region: SAM_7_link_chp; TIGR03915
720554003711	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554003712	PAS domain; Region: PAS_9; pfam13426
720554003713	putative active site [active]
720554003714	heme pocket [chemical binding]; other site
720554003715	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554003716	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554003717	metal binding site [ion binding]; metal-binding site
720554003718	active site
720554003719	I-site; other site
720554003720	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
720554003721	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
720554003722	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
720554003723	RNA polymerase factor sigma-70; Validated; Region: PRK06811
720554003724	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554003725	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554003726	DNA binding residues [nucleotide binding]
720554003727	Beta propeller domain; Region: Beta_propel; pfam09826
720554003728	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
720554003729	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
720554003730	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
720554003731	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
720554003732	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554003733	Walker A/P-loop; other site
720554003734	ATP binding site [chemical binding]; other site
720554003735	Q-loop/lid; other site
720554003736	ABC transporter signature motif; other site
720554003737	Walker B; other site
720554003738	D-loop; other site
720554003739	H-loop/switch region; other site
720554003740	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
720554003741	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554003742	FeS/SAM binding site; other site
720554003743	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
720554003744	Peptidase family M23; Region: Peptidase_M23; pfam01551
720554003745	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
720554003746	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
720554003747	dimanganese center [ion binding]; other site
720554003748	CotJB protein; Region: CotJB; pfam12652
720554003749	Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007
720554003750	Predicted amidohydrolase [General function prediction only]; Region: COG0388
720554003751	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
720554003752	putative active site [active]
720554003753	catalytic triad [active]
720554003754	dimer interface [polypeptide binding]; other site
720554003755	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
720554003756	16S/18S rRNA binding site [nucleotide binding]; other site
720554003757	S13e-L30e interaction site [polypeptide binding]; other site
720554003758	25S rRNA binding site [nucleotide binding]; other site
720554003759	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
720554003760	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
720554003761	RNase E interface [polypeptide binding]; other site
720554003762	trimer interface [polypeptide binding]; other site
720554003763	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
720554003764	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
720554003765	RNase E interface [polypeptide binding]; other site
720554003766	trimer interface [polypeptide binding]; other site
720554003767	active site
720554003768	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
720554003769	putative nucleic acid binding region [nucleotide binding]; other site
720554003770	G-X-X-G motif; other site
720554003771	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
720554003772	RNA binding site [nucleotide binding]; other site
720554003773	domain interface; other site
720554003774	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
720554003775	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
720554003776	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
720554003777	dipicolinate synthase subunit A; Reviewed; Region: PRK08306
720554003778	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; Region: 2-Hacid_dh_C; pfam02826
720554003779	dipicolinate synthase subunit B; Reviewed; Region: spoVFB; PRK08305
720554003780	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
720554003781	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
720554003782	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
720554003783	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
720554003784	Walker A motif; other site
720554003785	ATP binding site [chemical binding]; other site
720554003786	Walker B motif; other site
720554003787	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
720554003788	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
720554003789	Walker A motif; other site
720554003790	ATP binding site [chemical binding]; other site
720554003791	Walker B motif; other site
720554003792	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
720554003793	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
720554003794	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
720554003795	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
720554003796	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
720554003797	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
720554003798	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
720554003799	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
720554003800	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
720554003801	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
720554003802	active site
720554003803	YlzJ-like protein; Region: YlzJ; pfam14035
720554003804	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
720554003805	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
720554003806	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
720554003807	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
720554003808	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
720554003809	hypothetical protein; Provisional; Region: PRK00955
720554003810	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
720554003811	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
720554003812	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
720554003813	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
720554003814	homodimer interface [polypeptide binding]; other site
720554003815	NADP binding site [chemical binding]; other site
720554003816	substrate binding site [chemical binding]; other site
720554003817	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554003818	Walker B; other site
720554003819	D-loop; other site
720554003820	H-loop/switch region; other site
720554003821	V-type ATP synthase subunit E; Provisional; Region: PRK03963; cl17074
720554003822	phosphodiesterase; Provisional; Region: PRK12704
720554003823	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554003824	Zn2+ binding site [ion binding]; other site
720554003825	Mg2+ binding site [ion binding]; other site
720554003826	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
720554003827	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
720554003828	putative active site [active]
720554003829	metal binding site [ion binding]; metal-binding site
720554003830	homodimer binding site [polypeptide binding]; other site
720554003831	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
720554003832	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554003833	Transposase; Region: HTH_Tnp_1; cl17663
720554003834	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554003835	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554003836	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554003837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554003838	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554003839	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554003840	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554003841	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
720554003842	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
720554003843	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
720554003844	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
720554003845	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
720554003846	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
720554003847	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
720554003848	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554003849	NAD(P) binding site [chemical binding]; other site
720554003850	active site
720554003851	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3879
720554003852	Septum formation initiator; Region: DivIC; cl17659
720554003853	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
720554003854	Carbohydrate binding domain; Region: CBM_25; smart01066
720554003855	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
720554003856	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
720554003857	active site
720554003858	Substrate binding site; other site
720554003859	Mg++ binding site; other site
720554003860	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
720554003861	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
720554003862	putative trimer interface [polypeptide binding]; other site
720554003863	putative CoA binding site [chemical binding]; other site
720554003864	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
720554003865	GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity.  The protein contains an...; Region: MPG1_transferase; cd05805
720554003866	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
720554003867	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3879
720554003868	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
720554003869	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
720554003870	Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948
720554003871	NodB motif; other site
720554003872	active site
720554003873	catalytic site [active]
720554003874	Cd binding site [ion binding]; other site
720554003875	YabP family; Region: YabP; cl06766
720554003876	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
720554003877	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
720554003878	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
720554003879	PhoH-like protein; Region: PhoH; pfam02562
720554003880	7TM-HD extracellular; Region: 7TMR-HDED; pfam07697
720554003881	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
720554003882	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554003883	Zn2+ binding site [ion binding]; other site
720554003884	Mg2+ binding site [ion binding]; other site
720554003885	metal-binding heat shock protein; Provisional; Region: PRK00016
720554003886	GTPase Era; Reviewed; Region: era; PRK00089
720554003887	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
720554003888	G1 box; other site
720554003889	GTP/Mg2+ binding site [chemical binding]; other site
720554003890	Switch I region; other site
720554003891	G2 box; other site
720554003892	Switch II region; other site
720554003893	G3 box; other site
720554003894	G4 box; other site
720554003895	G5 box; other site
720554003896	YqzL-like protein; Region: YqzL; pfam14006
720554003897	Recombination protein O N terminal; Region: RecO_N; pfam11967
720554003898	DNA repair protein RecO; Region: reco; TIGR00613
720554003899	Recombination protein O C terminal; Region: RecO_C; pfam02565
720554003900	GEMM cis-regulatory element
720554003901	PilZ domain; Region: PilZ; pfam07238
720554003902	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
720554003903	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
720554003904	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
720554003905	catalytic residue [active]
720554003906	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
720554003907	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
720554003908	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
720554003909	Ligand Binding Site [chemical binding]; other site
720554003910	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
720554003911	VanW like protein; Region: VanW; pfam04294
720554003912	G5 domain; Region: G5; pfam07501
720554003913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655
720554003914	Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986
720554003915	AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like1; cd06061
720554003916	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypE; COG0309
720554003917	dimerization interface [polypeptide binding]; other site
720554003918	putative ATP binding site [chemical binding]; other site
720554003919	O-Antigen ligase; Region: Wzy_C; pfam04932
720554003920	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
720554003921	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
720554003922	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
720554003923	dimer interface [polypeptide binding]; other site
720554003924	active site
720554003925	glycine-pyridoxal phosphate binding site [chemical binding]; other site
720554003926	folate binding site [chemical binding]; other site
720554003927	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554003928	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554003929	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
720554003930	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
720554003931	Protein of unknown function DUF58; Region: DUF58; pfam01882
720554003932	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554003933	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554003934	Walker A motif; other site
720554003935	ATP binding site [chemical binding]; other site
720554003936	Walker B motif; other site
720554003937	arginine finger; other site
720554003938	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
720554003939	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
720554003940	NAD binding site [chemical binding]; other site
720554003941	dimer interface [polypeptide binding]; other site
720554003942	substrate binding site [chemical binding]; other site
720554003943	tetramer (dimer of dimers) interface [polypeptide binding]; other site
720554003944	competence damage-inducible protein A; Provisional; Region: PRK00549
720554003945	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
720554003946	putative MPT binding site; other site
720554003947	Competence-damaged protein; Region: CinA; pfam02464
720554003948	integral membrane protein MviN; Region: mviN; TIGR01695
720554003949	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
720554003950	recombinase A; Provisional; Region: recA; PRK09354
720554003951	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
720554003952	hexamer interface [polypeptide binding]; other site
720554003953	Walker A motif; other site
720554003954	ATP binding site [chemical binding]; other site
720554003955	Walker B motif; other site
720554003956	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
720554003957	HflK protein; Region: hflK; TIGR01933
720554003958	HflC protein; Region: hflC; TIGR01932
720554003959	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
720554003960	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
720554003961	Spore germination protein; Region: Spore_permease; cl17796
720554003962	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
720554003963	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
720554003964	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; pfam09989
720554003965	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
720554003966	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
720554003967	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554003968	putative active site [active]
720554003969	heme pocket [chemical binding]; other site
720554003970	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554003971	dimer interface [polypeptide binding]; other site
720554003972	phosphorylation site [posttranslational modification]
720554003973	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554003974	ATP binding site [chemical binding]; other site
720554003975	Mg2+ binding site [ion binding]; other site
720554003976	G-X-G motif; other site
720554003977	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
720554003978	pyrroline-5-carboxylate reductase; Region: PLN02688
720554003979	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
720554003980	RNA/DNA hybrid binding site [nucleotide binding]; other site
720554003981	active site
720554003982	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
720554003983	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
720554003984	dimer interface [polypeptide binding]; other site
720554003985	ADP-ribose binding site [chemical binding]; other site
720554003986	active site
720554003987	nudix motif; other site
720554003988	metal binding site [ion binding]; metal-binding site
720554003989	Integral membrane protein DUF95; Region: DUF95; cl00572
720554003990	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
720554003991	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
720554003992	active site
720554003993	Int/Topo IB signature motif; other site
720554003994	phosphopentomutase; Provisional; Region: PRK05362
720554003995	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
720554003996	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
720554003997	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
720554003998	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
720554003999	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
720554004000	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
720554004001	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
720554004002	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
720554004003	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
720554004004	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554004005	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554004006	Walker A motif; other site
720554004007	ATP binding site [chemical binding]; other site
720554004008	Walker B motif; other site
720554004009	arginine finger; other site
720554004010	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
720554004011	Protein of unknown function DUF58; Region: DUF58; pfam01882
720554004012	RDD family; Region: RDD; pfam06271
720554004013	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554004014	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554004015	Integrase core domain; Region: rve; pfam00665
720554004016	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
720554004017	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554004018	metal binding site [ion binding]; metal-binding site
720554004019	ligand binding site [chemical binding]; other site
720554004020	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004021	Domain of unknown function (DUF303); Region: DUF303; pfam03629
720554004022	diaminopimelate decarboxylase; Region: lysA; TIGR01048
720554004023	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
720554004024	active site
720554004025	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
720554004026	substrate binding site [chemical binding]; other site
720554004027	catalytic residues [active]
720554004028	dimer interface [polypeptide binding]; other site
720554004029	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
720554004030	Peptidase family M28; Region: Peptidase_M28; pfam04389
720554004031	metal binding site [ion binding]; metal-binding site
720554004032	DHH family; Region: DHH; pfam01368
720554004033	FOG: CBS domain [General function prediction only]; Region: COG0517
720554004034	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with an upstream DHH domain which performs a phosphoesterase function and a downstream polyA polymerase domain. CBS is a small domain originally...; Region: CBS_pair_DHH_polyA_Pol_assoc; cd04595
720554004035	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
720554004036	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
720554004037	active site
720554004038	NTP binding site [chemical binding]; other site
720554004039	metal binding triad [ion binding]; metal-binding site
720554004040	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
720554004041	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
720554004042	Peptidase family M50; Region: Peptidase_M50; pfam02163
720554004043	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
720554004044	active site
720554004045	putative substrate binding region [chemical binding]; other site
720554004046	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
720554004047	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
720554004048	active site
720554004049	HIGH motif; other site
720554004050	dimer interface [polypeptide binding]; other site
720554004051	KMSKS motif; other site
720554004052	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
720554004053	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
720554004054	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
720554004055	sporulation protein YtfJ; Region: spore_ytfJ; TIGR02874
720554004056	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
720554004057	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554004058	RNA binding surface [nucleotide binding]; other site
720554004059	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
720554004060	active site
720554004061	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
720554004062	spermidine synthase; Provisional; Region: PRK00811
720554004063	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554004064	S-adenosylmethionine binding site [chemical binding]; other site
720554004065	agmatinase; Region: agmatinase; TIGR01230
720554004066	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
720554004067	putative active site [active]
720554004068	Mn binding site [ion binding]; other site
720554004069	Methyltransferase domain; Region: Methyltransf_31; pfam13847
720554004070	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554004071	S-adenosylmethionine binding site [chemical binding]; other site
720554004072	PilZ domain; Region: PilZ; pfam07238
720554004073	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
720554004074	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
720554004075	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
720554004076	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
720554004077	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
720554004078	carboxyltransferase (CT) interaction site; other site
720554004079	biotinylation site [posttranslational modification]; other site
720554004080	oxaloacetate decarboxylase; Provisional; Region: PRK12331
720554004081	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
720554004082	active site
720554004083	catalytic residues [active]
720554004084	metal binding site [ion binding]; metal-binding site
720554004085	homodimer binding site [polypeptide binding]; other site
720554004086	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554004087	Interdomain contacts; other site
720554004088	Cytokine receptor motif; other site
720554004089	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554004090	Interdomain contacts; other site
720554004091	Cytokine receptor motif; other site
720554004092	Kelch motif; Region: Kelch_1; pfam01344
720554004093	Kelch domain; Region: Kelch; smart00612
720554004094	Kelch motif; Region: Kelch_1; pfam01344
720554004095	Kelch motif; Region: Kelch_1; pfam01344
720554004096	Kelch motif; Region: Kelch_1; pfam01344
720554004097	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554004098	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554004099	Domain of unknown function (DUF4304); Region: DUF4304; pfam14137
720554004100	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554004101	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004102	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554004103	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554004104	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554004105	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004106	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004107	Transposase; Region: HTH_Tnp_1; cl17663
720554004108	VirE N-terminal domain; Region: VirE_N; pfam08800
720554004109	D5 N terminal like; Region: D5_N; pfam08706
720554004110	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
720554004111	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
720554004112	Phage capsid family; Region: Phage_capsid; pfam05065
720554004113	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554004114	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554004115	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554004116	Transposase; Region: HTH_Tnp_1; cl17663
720554004117	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004118	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004119	RHS Repeat; Region: RHS_repeat; cl11982
720554004120	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554004121	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
720554004122	ADP-ribose binding site [chemical binding]; other site
720554004123	Transposase; Region: HTH_Tnp_1; cl17663
720554004124	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004125	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004126	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
720554004127	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
720554004128	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554004129	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554004130	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
720554004131	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
720554004132	putative ligand binding site [chemical binding]; other site
720554004133	DOMON-like type 9 carbohydrate binding module of xylanases; Region: CBM9_like_1; cd00005
720554004134	Ca binding site [ion binding]; other site
720554004135	carbohydrate binding site [chemical binding]; other site
720554004136	DOMON-like type 9 carbohydrate binding module of xylanases; Region: CBM9_like_1; cd00005
720554004137	Ca binding site [ion binding]; other site
720554004138	carbohydrate binding site [chemical binding]; other site
720554004139	S-layer homology domain; Region: SLH; pfam00395
720554004140	S-layer homology domain; Region: SLH; pfam00395
720554004141	S-layer homology domain; Region: SLH; pfam00395
720554004142	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004143	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004144	Transposase; Region: HTH_Tnp_1; cl17663
720554004145	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554004146	dimerization interface [polypeptide binding]; other site
720554004147	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554004148	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554004149	dimer interface [polypeptide binding]; other site
720554004150	putative CheW interface [polypeptide binding]; other site
720554004151	CHASE3 domain; Region: CHASE3; pfam05227
720554004152	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554004153	dimerization interface [polypeptide binding]; other site
720554004154	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554004155	dimer interface [polypeptide binding]; other site
720554004156	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
720554004157	putative CheW interface [polypeptide binding]; other site
720554004158	CHASE3 domain; Region: CHASE3; pfam05227
720554004159	Domain of unknown function (DUF303); Region: DUF303; pfam03629
720554004160	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004161	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004162	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
720554004163	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554004164	Coenzyme A binding pocket [chemical binding]; other site
720554004165	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
720554004166	TPR repeat; Region: TPR_11; pfam13414
720554004167	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004168	binding surface
720554004169	TPR motif; other site
720554004170	Tetratricopeptide repeat; Region: TPR_16; pfam13432
720554004171	TPR repeat; Region: TPR_11; pfam13414
720554004172	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004173	binding surface
720554004174	TPR motif; other site
720554004175	TPR repeat; Region: TPR_11; pfam13414
720554004176	TPR repeat; Region: TPR_11; pfam13414
720554004177	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004178	binding surface
720554004179	TPR motif; other site
720554004180	Tetratricopeptide repeat; Region: TPR_16; pfam13432
720554004181	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554004182	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004183	binding surface
720554004184	TPR motif; other site
720554004185	TPR repeat; Region: TPR_11; pfam13414
720554004186	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004187	Clostridium thermocellum (Cth)TTM and similar proteins, a subgroup of the CYTH-like superfamily; Region: CYTH-like_CthTTM-like; cd07761
720554004188	putative active site [active]
720554004189	putative metal binding residues [ion binding]; other site
720554004190	signature motif; other site
720554004191	putative dimer interface [polypeptide binding]; other site
720554004192	putative phosphate binding site [ion binding]; other site
720554004193	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
720554004194	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
720554004195	putative ATP binding site [chemical binding]; other site
720554004196	putative substrate interface [chemical binding]; other site
720554004197	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
720554004198	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554004199	Walker A/P-loop; other site
720554004200	ATP binding site [chemical binding]; other site
720554004201	Q-loop/lid; other site
720554004202	ABC transporter signature motif; other site
720554004203	Walker B; other site
720554004204	D-loop; other site
720554004205	H-loop/switch region; other site
720554004206	Predicted transcriptional regulators [Transcription]; Region: COG1725
720554004207	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
720554004208	DNA-binding site [nucleotide binding]; DNA binding site
720554004209	Protein of unknown function (DUF1538); Region: DUF1538; pfam07556
720554004210	Protein of unknown function (DUF1538); Region: DUF1538; pfam07556
720554004211	Nitrogen regulatory protein P-II; Region: P-II; smart00938
720554004212	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
720554004213	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004214	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004215	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
720554004216	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
720554004217	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
720554004218	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
720554004219	N-acetyl-D-glucosamine binding site [chemical binding]; other site
720554004220	catalytic residue [active]
720554004221	endoglucanase; Region: PLN02420
720554004222	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
720554004223	Cellulose binding domain; Region: CBM_3; cl03026
720554004224	Cellulose binding domain; Region: CBM_3; pfam00942
720554004225	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004226	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004227	endoglucanase; Region: PLN02420
720554004228	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554004229	Cellulose binding domain; Region: CBM_3; smart01067
720554004230	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004231	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004232	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
720554004233	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
720554004234	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554004235	FeS/SAM binding site; other site
720554004236	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
720554004237	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554004238	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554004239	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554004240	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
720554004241	biotin synthase; Provisional; Region: PRK07094
720554004242	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554004243	FeS/SAM binding site; other site
720554004244	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
720554004245	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
720554004246	Aspartase; Region: Aspartase; cd01357
720554004247	active sites [active]
720554004248	tetramer interface [polypeptide binding]; other site
720554004249	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
720554004250	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
720554004251	G1 box; other site
720554004252	GTP/Mg2+ binding site [chemical binding]; other site
720554004253	Switch I region; other site
720554004254	G2 box; other site
720554004255	Switch II region; other site
720554004256	G3 box; other site
720554004257	G4 box; other site
720554004258	G5 box; other site
720554004259	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
720554004260	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
720554004261	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
720554004262	catalytic residue [active]
720554004263	Cell division protein FtsA; Region: FtsA; cl17206
720554004264	Competence protein A; Region: Competence_A; pfam11104
720554004265	Cell division protein FtsA; Region: FtsA; pfam14450
720554004266	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
720554004267	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
720554004268	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
720554004269	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
720554004270	Walker A/P-loop; other site
720554004271	ATP binding site [chemical binding]; other site
720554004272	Q-loop/lid; other site
720554004273	ABC transporter signature motif; other site
720554004274	Walker B; other site
720554004275	D-loop; other site
720554004276	H-loop/switch region; other site
720554004277	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554004278	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554004279	dimer interface [polypeptide binding]; other site
720554004280	conserved gate region; other site
720554004281	putative PBP binding loops; other site
720554004282	ABC-ATPase subunit interface; other site
720554004283	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
720554004284	NMT1-like family; Region: NMT1_2; pfam13379
720554004285	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like; cd07473
720554004286	catalytic triad [active]
720554004287	putative active site [active]
720554004288	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
720554004289	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
720554004290	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554004291	dockerin binding interface; other site
720554004292	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554004293	Interdomain contacts; other site
720554004294	Cytokine receptor motif; other site
720554004295	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554004296	Interdomain contacts; other site
720554004297	Cytokine receptor motif; other site
720554004298	CARDB; Region: CARDB; pfam07705
720554004299	CARDB; Region: CARDB; pfam07705
720554004300	CARDB; Region: CARDB; pfam07705
720554004301	CARDB; Region: CARDB; pfam07705
720554004302	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554004303	metal ion-dependent adhesion site (MIDAS); other site
720554004304	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
720554004305	intermolecular salt bridges; other site
720554004306	calcium mediated ligand binding site; other site
720554004307	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
720554004308	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004309	protein-splicing catalytic site; other site
720554004310	thioester formation/cholesterol transfer; other site
720554004311	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004312	The BURPS668_1122 family of deaminases; Region: Toxin-deaminase; pfam14424
720554004313	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004314	protein-splicing catalytic site; other site
720554004315	thioester formation/cholesterol transfer; other site
720554004316	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004317	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554004318	Integrase core domain; Region: rve; pfam00665
720554004319	transposase; Provisional; Region: PRK06526
720554004320	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554004321	Walker A motif; other site
720554004322	ATP binding site [chemical binding]; other site
720554004323	Walker B motif; other site
720554004324	Transposase; Region: HTH_Tnp_1; cl17663
720554004325	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004326	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004327	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554004328	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004329	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554004330	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554004331	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554004332	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004333	protein-splicing catalytic site; other site
720554004334	thioester formation/cholesterol transfer; other site
720554004335	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004336	Immunity protein Imm5; Region: Imm5; pfam14423
720554004337	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554004338	MULE transposase domain; Region: MULE; pfam10551
720554004339	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004340	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004341	Transposase; Region: HTH_Tnp_1; cl17663
720554004342	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
720554004343	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554004344	Transposase; Region: HTH_Tnp_1; pfam01527
720554004345	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554004346	putative transposase OrfB; Reviewed; Region: PHA02517
720554004347	HTH-like domain; Region: HTH_21; pfam13276
720554004348	Integrase core domain; Region: rve; pfam00665
720554004349	Integrase core domain; Region: rve_3; pfam13683
720554004350	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554004351	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554004352	Integrase core domain; Region: rve; pfam00665
720554004353	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004354	protein-splicing catalytic site; other site
720554004355	thioester formation/cholesterol transfer; other site
720554004356	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004357	DYW family of nucleic acid deaminases; Region: DYW_deaminase; pfam14432
720554004358	Immunity protein Imm5; Region: Imm5; pfam14423
720554004359	Transposase; Region: HTH_Tnp_1; cl17663
720554004360	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554004361	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554004362	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
720554004363	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
720554004364	DDE domain; Region: DDE_Tnp_IS240; pfam13610
720554004365	Integrase core domain; Region: rve; pfam00665
720554004366	Integrase core domain; Region: rve_3; pfam13683
720554004367	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004368	protein-splicing catalytic site; other site
720554004369	thioester formation/cholesterol transfer; other site
720554004370	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004371	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004372	protein-splicing catalytic site; other site
720554004373	thioester formation/cholesterol transfer; other site
720554004374	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004375	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554004376	protein-splicing catalytic site; other site
720554004377	thioester formation/cholesterol transfer; other site
720554004378	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554004379	The BURPS668_1122 family of deaminases; Region: Toxin-deaminase; pfam14424
720554004380	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554004381	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554004382	putative Zn2+ binding site [ion binding]; other site
720554004383	putative DNA binding site [nucleotide binding]; other site
720554004384	Integrase core domain; Region: rve; pfam00665
720554004385	transposase; Provisional; Region: PRK06526
720554004386	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554004387	Walker A motif; other site
720554004388	ATP binding site [chemical binding]; other site
720554004389	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
720554004390	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
720554004391	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
720554004392	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
720554004393	radical SAM/SPASM domain Clo7bot peptide maturase; Region: rSAM_Clo7bot; TIGR04334
720554004394	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554004395	FeS/SAM binding site; other site
720554004396	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
720554004397	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554004398	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
720554004399	3D domain; Region: 3D; pfam06725
720554004400	recombination regulator RecX; Reviewed; Region: recX; PRK00117
720554004401	Predicted membrane protein [Function unknown]; Region: COG1971
720554004402	Domain of unknown function DUF; Region: DUF204; pfam02659
720554004403	Domain of unknown function DUF; Region: DUF204; pfam02659
720554004404	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
720554004405	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
720554004406	active site
720554004407	metal binding site [ion binding]; metal-binding site
720554004408	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554004409	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
720554004410	TPR repeat; Region: TPR_11; pfam13414
720554004411	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004412	binding surface
720554004413	TPR motif; other site
720554004414	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004415	TPR motif; other site
720554004416	binding surface
720554004417	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
720554004418	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554004419	Fibronectin type 3 domain; Region: FN3; smart00060
720554004420	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
720554004421	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554004422	Interdomain contacts; other site
720554004423	Cytokine receptor motif; other site
720554004424	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
720554004425	active site
720554004426	NTP binding site [chemical binding]; other site
720554004427	metal binding triad [ion binding]; metal-binding site
720554004428	antibiotic binding site [chemical binding]; other site
720554004429	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01710
720554004430	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554004431	Methyltransferase domain; Region: Methyltransf_31; pfam13847
720554004432	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554004433	S-adenosylmethionine binding site [chemical binding]; other site
720554004434	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
720554004435	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
720554004436	oligomer interface [polypeptide binding]; other site
720554004437	active site
720554004438	metal binding site [ion binding]; metal-binding site
720554004439	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
720554004440	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
720554004441	oligomer interface [polypeptide binding]; other site
720554004442	active site
720554004443	metal binding site [ion binding]; metal-binding site
720554004444	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
720554004445	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
720554004446	oligomer interface [polypeptide binding]; other site
720554004447	active site
720554004448	metal binding site [ion binding]; metal-binding site
720554004449	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
720554004450	Uncharacterized conserved protein [Function unknown]; Region: COG1434
720554004451	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
720554004452	putative active site [active]
720554004453	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
720554004454	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554004455	Beta-Casp domain; Region: Beta-Casp; smart01027
720554004456	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
720554004457	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554004458	S-adenosylmethionine binding site [chemical binding]; other site
720554004459	enoyl-CoA hydratase; Provisional; Region: PRK06688
720554004460	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
720554004461	substrate binding site [chemical binding]; other site
720554004462	oxyanion hole (OAH) forming residues; other site
720554004463	trimer interface [polypeptide binding]; other site
720554004464	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
720554004465	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554004466	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554004467	putative active site [active]
720554004468	putative NTP binding site [chemical binding]; other site
720554004469	putative nucleic acid binding site [nucleotide binding]; other site
720554004470	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554004471	Helix-turn-helix domain; Region: HTH_17; pfam12728
720554004472	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
720554004473	HsdM N-terminal domain; Region: HsdM_N; pfam12161
720554004474	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554004475	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554004476	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
720554004477	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
720554004478	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
720554004479	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554004480	ATP binding site [chemical binding]; other site
720554004481	putative Mg++ binding site [ion binding]; other site
720554004482	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
720554004483	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
720554004484	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554004485	ATP binding site [chemical binding]; other site
720554004486	putative Mg++ binding site [ion binding]; other site
720554004487	helicase superfamily c-terminal domain; Region: HELICc; smart00490
720554004488	ATP-binding site [chemical binding]; other site
720554004489	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
720554004490	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554004491	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554004492	Integrase core domain; Region: rve; pfam00665
720554004493	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
720554004494	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
720554004495	PBP superfamily domain; Region: PBP_like_2; cl17296
720554004496	PBP superfamily domain; Region: PBP_like_2; cl17296
720554004497	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
720554004498	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554004499	dimer interface [polypeptide binding]; other site
720554004500	conserved gate region; other site
720554004501	putative PBP binding loops; other site
720554004502	ABC-ATPase subunit interface; other site
720554004503	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
720554004504	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554004505	dimer interface [polypeptide binding]; other site
720554004506	conserved gate region; other site
720554004507	putative PBP binding loops; other site
720554004508	ABC-ATPase subunit interface; other site
720554004509	phosphate transporter ATP-binding protein; Provisional; Region: PRK14240
720554004510	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
720554004511	Walker A/P-loop; other site
720554004512	ATP binding site [chemical binding]; other site
720554004513	Q-loop/lid; other site
720554004514	ABC transporter signature motif; other site
720554004515	Walker B; other site
720554004516	D-loop; other site
720554004517	H-loop/switch region; other site
720554004518	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
720554004519	PhoU domain; Region: PhoU; pfam01895
720554004520	PhoU domain; Region: PhoU; pfam01895
720554004521	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554004522	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554004523	active site
720554004524	phosphorylation site [posttranslational modification]
720554004525	intermolecular recognition site; other site
720554004526	dimerization interface [polypeptide binding]; other site
720554004527	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554004528	DNA binding site [nucleotide binding]
720554004529	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
720554004530	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554004531	heme pocket [chemical binding]; other site
720554004532	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554004533	dimer interface [polypeptide binding]; other site
720554004534	phosphorylation site [posttranslational modification]
720554004535	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554004536	ATP binding site [chemical binding]; other site
720554004537	Mg2+ binding site [ion binding]; other site
720554004538	G-X-G motif; other site
720554004539	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
720554004540	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
720554004541	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554004542	Walker A/P-loop; other site
720554004543	ATP binding site [chemical binding]; other site
720554004544	Q-loop/lid; other site
720554004545	ABC transporter signature motif; other site
720554004546	Walker B; other site
720554004547	D-loop; other site
720554004548	H-loop/switch region; other site
720554004549	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
720554004550	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554004551	non-specific DNA binding site [nucleotide binding]; other site
720554004552	salt bridge; other site
720554004553	sequence-specific DNA binding site [nucleotide binding]; other site
720554004554	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
720554004555	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
720554004556	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
720554004557	active site
720554004558	catalytic tetrad [active]
720554004559	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554004560	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
720554004561	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
720554004562	acyl-activating enzyme (AAE) consensus motif; other site
720554004563	putative AMP binding site [chemical binding]; other site
720554004564	putative active site [active]
720554004565	putative CoA binding site [chemical binding]; other site
720554004566	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
720554004567	active site
720554004568	catalytic motif [active]
720554004569	Zn binding site [ion binding]; other site
720554004570	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
720554004571	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
720554004572	TM-ABC transporter signature motif; other site
720554004573	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
720554004574	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
720554004575	TM-ABC transporter signature motif; other site
720554004576	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
720554004577	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554004578	Walker A/P-loop; other site
720554004579	ATP binding site [chemical binding]; other site
720554004580	Q-loop/lid; other site
720554004581	ABC transporter signature motif; other site
720554004582	Walker B; other site
720554004583	D-loop; other site
720554004584	H-loop/switch region; other site
720554004585	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
720554004586	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
720554004587	4Fe-4S binding domain; Region: Fer4; pfam00037
720554004588	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554004589	FeS/SAM binding site; other site
720554004590	Protein of unknown function (DUF3029); Region: DUF3029; pfam11230
720554004591	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
720554004592	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
720554004593	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
720554004594	ligand binding site [chemical binding]; other site
720554004595	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
720554004596	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
720554004597	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
720554004598	putative active site pocket [active]
720554004599	dimerization interface [polypeptide binding]; other site
720554004600	putative catalytic residue [active]
720554004601	PUA domain; Region: PUA; cl00607
720554004602	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
720554004603	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
720554004604	putative RNA binding site [nucleotide binding]; other site
720554004605	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554004606	S-adenosylmethionine binding site [chemical binding]; other site
720554004607	indolepyruvate ferredoxin oxidoreductase, alpha subunit; Region: IOR_alpha; TIGR03336
720554004608	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
720554004609	dimer interface [polypeptide binding]; other site
720554004610	PYR/PP interface [polypeptide binding]; other site
720554004611	TPP binding site [chemical binding]; other site
720554004612	substrate binding site [chemical binding]; other site
720554004613	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
720554004614	TPP-binding site; other site
720554004615	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
720554004616	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
720554004617	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
720554004618	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
720554004619	acyl-activating enzyme (AAE) consensus motif; other site
720554004620	AMP binding site [chemical binding]; other site
720554004621	active site
720554004622	CoA binding site [chemical binding]; other site
720554004623	ACT domain-containing protein [General function prediction only]; Region: COG4747
720554004624	N-terminal ACT domain of a novel protein composed almost entirely of two tandem ACT domains; Region: ACT_Bt0572_1; cd04908
720554004625	C-terminal ACT domain of a novel protein composed of just two ACT domains; Region: ACT_Bt0572_2; cd04882
720554004626	recombination factor protein RarA; Reviewed; Region: PRK13342
720554004627	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554004628	Walker A motif; other site
720554004629	ATP binding site [chemical binding]; other site
720554004630	Walker B motif; other site
720554004631	arginine finger; other site
720554004632	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
720554004633	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554004634	active site
720554004635	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328
720554004636	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
720554004637	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554004638	FeS/SAM binding site; other site
720554004639	TRAM domain; Region: TRAM; pfam01938
720554004640	Protein of unknown function (DUF964); Region: DUF964; pfam06133
720554004641	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
720554004642	MutS domain I; Region: MutS_I; pfam01624
720554004643	MutS domain II; Region: MutS_II; pfam05188
720554004644	MutS domain III; Region: MutS_III; pfam05192
720554004645	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
720554004646	Walker A/P-loop; other site
720554004647	ATP binding site [chemical binding]; other site
720554004648	Q-loop/lid; other site
720554004649	ABC transporter signature motif; other site
720554004650	Walker B; other site
720554004651	D-loop; other site
720554004652	H-loop/switch region; other site
720554004653	DNA mismatch repair protein MutL; Region: mutl; TIGR00585
720554004654	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554004655	ATP binding site [chemical binding]; other site
720554004656	Mg2+ binding site [ion binding]; other site
720554004657	G-X-G motif; other site
720554004658	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
720554004659	ATP binding site [chemical binding]; other site
720554004660	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
720554004661	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
720554004662	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
720554004663	bacterial Hfq-like; Region: Hfq; cd01716
720554004664	hexamer interface [polypeptide binding]; other site
720554004665	Sm1 motif; other site
720554004666	RNA binding site [nucleotide binding]; other site
720554004667	Sm2 motif; other site
720554004668	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
720554004669	LexA repressor; Validated; Region: PRK00215
720554004670	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
720554004671	Catalytic site [active]
720554004672	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554004673	Ring-infected erythrocyte surface antigen; Provisional; Region: PTZ00341
720554004674	TadE-like protein; Region: TadE; pfam07811
720554004675	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
720554004676	CoenzymeA binding site [chemical binding]; other site
720554004677	subunit interaction site [polypeptide binding]; other site
720554004678	PHB binding site; other site
720554004679	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
720554004680	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554004681	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554004682	DNA binding residues [nucleotide binding]
720554004683	Putative zinc-finger; Region: zf-HC2; pfam13490
720554004684	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
720554004685	Sporulation protein YtfJ (Spore_YtfJ); Region: Spore_YtfJ; cl01596
720554004686	putative DNA-binding protein; Validated; Region: PRK00118
720554004687	signal recognition particle protein; Provisional; Region: PRK10867
720554004688	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
720554004689	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
720554004690	P loop; other site
720554004691	GTP binding site [chemical binding]; other site
720554004692	Signal peptide binding domain; Region: SRP_SPB; pfam02978
720554004693	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
720554004694	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
720554004695	hypothetical protein; Provisional; Region: PRK00468
720554004696	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
720554004697	RimM N-terminal domain; Region: RimM; pfam01782
720554004698	PRC-barrel domain; Region: PRC; pfam05239
720554004699	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
720554004700	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
720554004701	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554004702	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554004703	Chromate transporter; Region: Chromate_transp; pfam02417
720554004704	Chromate transporter; Region: Chromate_transp; pfam02417
720554004705	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
720554004706	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
720554004707	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
720554004708	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
720554004709	substrate binding site [chemical binding]; other site
720554004710	glutamase interaction surface [polypeptide binding]; other site
720554004711	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
720554004712	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554004713	substrate binding pocket [chemical binding]; other site
720554004714	membrane-bound complex binding site; other site
720554004715	hinge residues; other site
720554004716	HEAT repeats; Region: HEAT_2; pfam13646
720554004717	Chorismate mutase type II; Region: CM_2; cl00693
720554004718	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
720554004719	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554004720	Cna protein B-type domain; Region: Cna_B_2; pfam13715
720554004721	S-layer homology domain; Region: SLH; pfam00395
720554004722	S-layer homology domain; Region: SLH; pfam00395
720554004723	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554004724	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554004725	dimer interface [polypeptide binding]; other site
720554004726	putative CheW interface [polypeptide binding]; other site
720554004727	VanW like protein; Region: VanW; pfam04294
720554004728	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
720554004729	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
720554004730	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
720554004731	tRNA; other site
720554004732	putative tRNA binding site [nucleotide binding]; other site
720554004733	putative NADP binding site [chemical binding]; other site
720554004734	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
720554004735	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
720554004736	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
720554004737	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
720554004738	domain interfaces; other site
720554004739	active site
720554004740	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
720554004741	active site
720554004742	SAM binding site [chemical binding]; other site
720554004743	homodimer interface [polypeptide binding]; other site
720554004744	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
720554004745	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
720554004746	active site
720554004747	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
720554004748	dimer interface [polypeptide binding]; other site
720554004749	active site
720554004750	Schiff base residues; other site
720554004751	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
720554004752	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
720554004753	inhibitor-cofactor binding pocket; inhibition site
720554004754	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554004755	catalytic residue [active]
720554004756	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
720554004757	putative active site [active]
720554004758	para-aminobenzoate synthase component I; Validated; Region: PRK07093
720554004759	hypothetical protein; Provisional; Region: PRK07101
720554004760	substrate-cofactor binding pocket; other site
720554004761	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
720554004762	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554004763	DNA-binding interface [nucleotide binding]; DNA binding site
720554004764	Integrase core domain; Region: rve; pfam00665
720554004765	transposase/IS protein; Provisional; Region: PRK09183
720554004766	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554004767	Walker A motif; other site
720554004768	ATP binding site [chemical binding]; other site
720554004769	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
720554004770	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
720554004771	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004772	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004773	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
720554004774	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
720554004775	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
720554004776	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
720554004777	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
720554004778	active site
720554004779	DNA binding site [nucleotide binding]
720554004780	Int/Topo IB signature motif; other site
720554004781	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004782	dockerin binding interface; other site
720554004783	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004784	dockerin binding interface; other site
720554004785	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004786	dockerin binding interface; other site
720554004787	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004788	dockerin binding interface; other site
720554004789	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004790	dockerin binding interface; other site
720554004791	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004792	dockerin binding interface; other site
720554004793	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554004794	dockerin binding interface; other site
720554004795	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
720554004796	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
720554004797	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
720554004798	Trp docking motif [polypeptide binding]; other site
720554004799	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
720554004800	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
720554004801	DNA-binding site [nucleotide binding]; DNA binding site
720554004802	UTRA domain; Region: UTRA; pfam07702
720554004803	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
720554004804	Adenylsuccinate lyase (ASL)_subgroup 2; Region: Adenylsuccinate_lyase_2; cd03302
720554004805	tetramer interface [polypeptide binding]; other site
720554004806	active site
720554004807	aspartate aminotransferase; Provisional; Region: PRK05764
720554004808	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554004809	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554004810	homodimer interface [polypeptide binding]; other site
720554004811	catalytic residue [active]
720554004812	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
720554004813	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
720554004814	active site
720554004815	dimer interface [polypeptide binding]; other site
720554004816	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
720554004817	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004818	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004819	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
720554004820	hypothetical protein; Reviewed; Region: PRK00024
720554004821	helix-hairpin-helix signature motif; other site
720554004822	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
720554004823	MPN+ (JAMM) motif; other site
720554004824	Zinc-binding site [ion binding]; other site
720554004825	hypothetical protein; Reviewed; Region: PRK12497
720554004826	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
720554004827	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
720554004828	lichenase, member of glycosyl hydrolase family 16; Region: GH16_lichenase; cd02175
720554004829	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
720554004830	active site
720554004831	active site
720554004832	catalytic residues [active]
720554004833	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004834	Transcriptional regulators [Transcription]; Region: PurR; COG1609
720554004835	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
720554004836	DNA binding site [nucleotide binding]
720554004837	domain linker motif; other site
720554004838	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
720554004839	dimerization interface [polypeptide binding]; other site
720554004840	ligand binding site [chemical binding]; other site
720554004841	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
720554004842	RNA/DNA hybrid binding site [nucleotide binding]; other site
720554004843	active site
720554004844	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
720554004845	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
720554004846	GTP/Mg2+ binding site [chemical binding]; other site
720554004847	G4 box; other site
720554004848	G5 box; other site
720554004849	G1 box; other site
720554004850	Switch I region; other site
720554004851	G2 box; other site
720554004852	G3 box; other site
720554004853	Switch II region; other site
720554004854	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
720554004855	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
720554004856	Catalytic site [active]
720554004857	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
720554004858	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554004859	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554004860	Integrase core domain; Region: rve; pfam00665
720554004861	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
720554004862	HSP70 interaction site [polypeptide binding]; other site
720554004863	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004864	binding surface
720554004865	TPR motif; other site
720554004866	Tetratricopeptide repeat; Region: TPR_16; pfam13432
720554004867	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004868	binding surface
720554004869	TPR motif; other site
720554004870	Tetratricopeptide repeat; Region: TPR_16; pfam13432
720554004871	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004872	binding surface
720554004873	TPR motif; other site
720554004874	TPR repeat; Region: TPR_11; pfam13414
720554004875	TPR repeat; Region: TPR_11; pfam13414
720554004876	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004877	binding surface
720554004878	TPR motif; other site
720554004879	TPR repeat; Region: TPR_11; pfam13414
720554004880	TPR repeat; Region: TPR_11; pfam13414
720554004881	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554004882	binding surface
720554004883	TPR motif; other site
720554004884	TPR repeat; Region: TPR_11; pfam13414
720554004885	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
720554004886	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
720554004887	nucleotide binding site [chemical binding]; other site
720554004888	putative NEF/HSP70 interaction site [polypeptide binding]; other site
720554004889	SBD interface [polypeptide binding]; other site
720554004890	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554004891	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554004892	dimer interface [polypeptide binding]; other site
720554004893	putative CheW interface [polypeptide binding]; other site
720554004894	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
720554004895	putative metal binding site [ion binding]; other site
720554004896	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
720554004897	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004898	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554004899	RDD family; Region: RDD; pfam06271
720554004900	peptidylprolyl isomerase; Reviewed; Region: prsA; PRK03002
720554004901	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
720554004902	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
720554004903	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
720554004904	putative substrate binding site [chemical binding]; other site
720554004905	putative ATP binding site [chemical binding]; other site
720554004906	PilZ domain; Region: PilZ; pfam07238
720554004907	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
720554004908	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
720554004909	Tetramer interface [polypeptide binding]; other site
720554004910	active site
720554004911	FMN-binding site [chemical binding]; other site
720554004912	shikimate kinase; Reviewed; Region: aroK; PRK00131
720554004913	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
720554004914	ADP binding site [chemical binding]; other site
720554004915	magnesium binding site [ion binding]; other site
720554004916	putative shikimate binding site; other site
720554004917	Transcriptional regulator [Transcription]; Region: LytR; COG1316
720554004918	M18 Peptidase Aminopeptidase I; Region: M18_API; cd05659
720554004919	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
720554004920	oligomer interface [polypeptide binding]; other site
720554004921	putative active site [active]
720554004922	metal binding site [ion binding]; metal-binding site
720554004923	Response regulator receiver domain; Region: Response_reg; pfam00072
720554004924	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554004925	active site
720554004926	phosphorylation site [posttranslational modification]
720554004927	intermolecular recognition site; other site
720554004928	dimerization interface [polypeptide binding]; other site
720554004929	Domain of unknown function (DUF3369); Region: DUF3369; pfam11849
720554004930	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554004931	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554004932	Zn2+ binding site [ion binding]; other site
720554004933	Mg2+ binding site [ion binding]; other site
720554004934	histidinol-phosphatase; Provisional; Region: PRK05588
720554004935	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
720554004936	active site
720554004937	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
720554004938	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
720554004939	active site
720554004940	HIGH motif; other site
720554004941	dimer interface [polypeptide binding]; other site
720554004942	KMSKS motif; other site
720554004943	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554004944	RNA binding surface [nucleotide binding]; other site
720554004945	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
720554004946	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
720554004947	Ligand Binding Site [chemical binding]; other site
720554004948	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
720554004949	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
720554004950	trimerization site [polypeptide binding]; other site
720554004951	active site
720554004952	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
720554004953	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
720554004954	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
720554004955	catalytic residue [active]
720554004956	Transcriptional regulator; Region: Rrf2; cl17282
720554004957	Rrf2 family protein; Region: rrf2_super; TIGR00738
720554004958	Uncharacterized protein family (UPF0180); Region: UPF0180; cl04214
720554004959	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
720554004960	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
720554004961	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554004962	S-adenosylmethionine binding site [chemical binding]; other site
720554004963	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
720554004964	active site
720554004965	multimer interface [polypeptide binding]; other site
720554004966	S-adenosylmethionine decarboxylase proenzyme; Provisional; Region: PRK03124
720554004967	4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; Reviewed; Region: PRK00087
720554004968	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
720554004969	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
720554004970	RNA binding site [nucleotide binding]; other site
720554004971	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
720554004972	RNA binding site [nucleotide binding]; other site
720554004973	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
720554004974	RNA binding site [nucleotide binding]; other site
720554004975	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
720554004976	RNA binding site [nucleotide binding]; other site
720554004977	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
720554004978	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
720554004979	putative acyl-acceptor binding pocket; other site
720554004980	cytidylate kinase; Provisional; Region: cmk; PRK00023
720554004981	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
720554004982	CMP-binding site; other site
720554004983	The sites determining sugar specificity; other site
720554004984	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
720554004985	homotrimer interaction site [polypeptide binding]; other site
720554004986	active site
720554004987	Histidine Utilizing Protein, the hut operon positive regulatory protein; Region: HutP; cd11640
720554004988	hexamer interface [polypeptide binding]; other site
720554004989	RNA binding site [nucleotide binding]; other site
720554004990	Histidine-zinc binding site [chemical binding]; other site
720554004991	HI0933-like protein; Region: HI0933_like; pfam03486
720554004992	L-aspartate oxidase; Provisional; Region: PRK06175
720554004993	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
720554004994	catalytic core [active]
720554004995	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
720554004996	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
720554004997	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
720554004998	putative active site [active]
720554004999	Protein of unknown function (DUF4264); Region: DUF4264; pfam14084
720554005000	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
720554005001	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
720554005002	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
720554005003	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
720554005004	active site
720554005005	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
720554005006	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
720554005007	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
720554005008	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
720554005009	active site
720554005010	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
720554005011	active site
720554005012	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
720554005013	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
720554005014	putative NADP binding site [chemical binding]; other site
720554005015	active site
720554005016	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
720554005017	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
720554005018	acyl-activating enzyme (AAE) consensus motif; other site
720554005019	AMP binding site [chemical binding]; other site
720554005020	active site
720554005021	CoA binding site [chemical binding]; other site
720554005022	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
720554005023	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
720554005024	dimer interface [polypeptide binding]; other site
720554005025	active site
720554005026	CoA binding pocket [chemical binding]; other site
720554005027	Phosphopantetheine attachment site; Region: PP-binding; cl09936
720554005028	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
720554005029	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
720554005030	active site
720554005031	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005032	Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism]; Region: COG4305
720554005033	Glycosyl hydrolase family 81; Region: Glyco_hydro_81; cl02310
720554005034	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005035	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005036	endoglucanase; Region: PLN02420
720554005037	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554005038	Cellulose binding domain; Region: CBM_3; cl03026
720554005039	Cellulose binding domain; Region: CBM_3; pfam00942
720554005040	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005041	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005042	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
720554005043	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
720554005044	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
720554005045	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
720554005046	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
720554005047	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005048	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
720554005049	substrate binding site [chemical binding]; other site
720554005050	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
720554005051	active site
720554005052	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
720554005053	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
720554005054	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
720554005055	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
720554005056	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
720554005057	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
720554005058	RNA polymerase sigma factor SigY; Reviewed; Region: PRK09638
720554005059	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005060	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554005061	DNA binding residues [nucleotide binding]
720554005062	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
720554005063	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
720554005064	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
720554005065	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
720554005066	Walker A/P-loop; other site
720554005067	ATP binding site [chemical binding]; other site
720554005068	Q-loop/lid; other site
720554005069	ABC transporter signature motif; other site
720554005070	Walker B; other site
720554005071	D-loop; other site
720554005072	H-loop/switch region; other site
720554005073	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
720554005074	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554005075	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005076	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554005077	DNA binding residues [nucleotide binding]
720554005078	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
720554005079	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
720554005080	active site
720554005081	FMN binding site [chemical binding]; other site
720554005082	substrate binding site [chemical binding]; other site
720554005083	putative catalytic residue [active]
720554005084	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
720554005085	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554005086	OPT oligopeptide transporter protein; Region: OPT; cl14607
720554005087	putative oligopeptide transporter, OPT family; Region: TIGR00733
720554005088	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
720554005089	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
720554005090	metal binding site [ion binding]; metal-binding site
720554005091	dimer interface [polypeptide binding]; other site
720554005092	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
720554005093	Protein of unknown function (DUF554); Region: DUF554; pfam04474
720554005094	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
720554005095	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
720554005096	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
720554005097	catalytic residue [active]
720554005098	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005099	SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833
720554005100	active site
720554005101	oxyanion hole [active]
720554005102	catalytic triad [active]
720554005103	Penicillinase repressor; Region: Pencillinase_R; pfam03965
720554005104	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
720554005105	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
720554005106	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
720554005107	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
720554005108	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005109	dimer interface [polypeptide binding]; other site
720554005110	conserved gate region; other site
720554005111	putative PBP binding loops; other site
720554005112	ABC-ATPase subunit interface; other site
720554005113	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005114	putative PBP binding loops; other site
720554005115	ABC-ATPase subunit interface; other site
720554005116	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
720554005117	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
720554005118	Walker A/P-loop; other site
720554005119	ATP binding site [chemical binding]; other site
720554005120	Q-loop/lid; other site
720554005121	ABC transporter signature motif; other site
720554005122	Walker B; other site
720554005123	D-loop; other site
720554005124	H-loop/switch region; other site
720554005125	TOBE domain; Region: TOBE_2; pfam08402
720554005126	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
720554005127	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554005128	non-specific DNA binding site [nucleotide binding]; other site
720554005129	salt bridge; other site
720554005130	sequence-specific DNA binding site [nucleotide binding]; other site
720554005131	Cupin domain; Region: Cupin_2; pfam07883
720554005132	DNA polymerase III PolC; Validated; Region: polC; PRK00448
720554005133	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
720554005134	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
720554005135	generic binding surface II; other site
720554005136	generic binding surface I; other site
720554005137	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
720554005138	active site
720554005139	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
720554005140	active site
720554005141	catalytic site [active]
720554005142	substrate binding site [chemical binding]; other site
720554005143	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
720554005144	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
720554005145	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
720554005146	Int/Topo IB signature motif; other site
720554005147	Helix-turn-helix domain; Region: HTH_17; pfam12728
720554005148	CRISPR/Cas system-associated transcriptional regulator CasRa; Region: CasRa_I-A; cd09655
720554005149	DNA methylase; Region: N6_N4_Mtase; cl17433
720554005150	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554005151	non-specific DNA binding site [nucleotide binding]; other site
720554005152	salt bridge; other site
720554005153	sequence-specific DNA binding site [nucleotide binding]; other site
720554005154	Restriction endonuclease [Defense mechanisms]; Region: COG3587
720554005155	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554005156	ATP binding site [chemical binding]; other site
720554005157	DNA methylase; Region: N6_N4_Mtase; pfam01555
720554005158	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
720554005159	DNA methylase; Region: N6_N4_Mtase; cl17433
720554005160	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
720554005161	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_c; cd10311
720554005162	putative active site [active]
720554005163	catalytic site [active]
720554005164	DEAD-like helicases superfamily; Region: DEXDc; smart00487
720554005165	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554005166	ATP binding site [chemical binding]; other site
720554005167	putative Mg++ binding site [ion binding]; other site
720554005168	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554005169	nucleotide binding region [chemical binding]; other site
720554005170	ATP-binding site [chemical binding]; other site
720554005171	Helix-turn-helix domain; Region: HTH_17; pfam12728
720554005172	multiple promoter invertase; Provisional; Region: mpi; PRK13413
720554005173	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
720554005174	catalytic residues [active]
720554005175	catalytic nucleophile [active]
720554005176	Presynaptic Site I dimer interface [polypeptide binding]; other site
720554005177	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
720554005178	Synaptic Flat tetramer interface [polypeptide binding]; other site
720554005179	Synaptic Site I dimer interface [polypeptide binding]; other site
720554005180	DNA binding site [nucleotide binding]
720554005181	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554005182	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554005183	putative transposase OrfB; Reviewed; Region: PHA02517
720554005184	HTH-like domain; Region: HTH_21; pfam13276
720554005185	Integrase core domain; Region: rve; pfam00665
720554005186	Integrase core domain; Region: rve_3; pfam13683
720554005187	Transposase; Region: HTH_Tnp_1; pfam01527
720554005188	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554005189	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
720554005190	Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; pfam04277
720554005191	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
720554005192	active site
720554005193	catalytic site [active]
720554005194	substrate binding site [chemical binding]; other site
720554005195	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
720554005196	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554005197	FeS/SAM binding site; other site
720554005198	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
720554005199	Pyruvate formate lyase 1; Region: PFL1; cd01678
720554005200	coenzyme A binding site [chemical binding]; other site
720554005201	active site
720554005202	catalytic residues [active]
720554005203	glycine loop; other site
720554005204	Protein of unknown function (DUF342); Region: DUF342; pfam03961
720554005205	RNA polymerase sigma factor WhiG; Reviewed; Region: PRK06288
720554005206	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005207	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
720554005208	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554005209	DNA binding residues [nucleotide binding]
720554005210	CheD chemotactic sensory transduction; Region: CheD; cl00810
720554005211	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
720554005212	CheC-like family; Region: CheC; pfam04509
720554005213	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
720554005214	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
720554005215	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
720554005216	putative binding surface; other site
720554005217	active site
720554005218	P2 response regulator binding domain; Region: P2; pfam07194
720554005219	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
720554005220	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554005221	ATP binding site [chemical binding]; other site
720554005222	Mg2+ binding site [ion binding]; other site
720554005223	G-X-G motif; other site
720554005224	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
720554005225	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
720554005226	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005227	active site
720554005228	phosphorylation site [posttranslational modification]
720554005229	intermolecular recognition site; other site
720554005230	dimerization interface [polypeptide binding]; other site
720554005231	CheB methylesterase; Region: CheB_methylest; pfam01339
720554005232	Flagellar protein YcgR; Region: YcgR_2; pfam12945
720554005233	PilZ domain; Region: PilZ; pfam07238
720554005234	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
720554005235	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554005236	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
720554005237	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
720554005238	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554005239	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
720554005240	FHIPEP family; Region: FHIPEP; pfam00771
720554005241	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
720554005242	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
720554005243	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
720554005244	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
720554005245	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
720554005246	flagellar biosynthetic protein FliO; Region: FliO_TIGR; TIGR03500
720554005247	Response regulator receiver domain; Region: Response_reg; pfam00072
720554005248	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005249	active site
720554005250	phosphorylation site [posttranslational modification]
720554005251	intermolecular recognition site; other site
720554005252	dimerization interface [polypeptide binding]; other site
720554005253	flagellar motor switch protein; Validated; Region: PRK08119
720554005254	CheC-like family; Region: CheC; pfam04509
720554005255	CheC-like family; Region: CheC; pfam04509
720554005256	flagellar motor switch protein FliN; Region: fliN; TIGR02480
720554005257	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
720554005258	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
720554005259	Flagellar basal body-associated protein FliL; Region: FliL; cl00681
720554005260	Flagellar protein (FlbD); Region: FlbD; pfam06289
720554005261	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
720554005262	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
720554005263	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
720554005264	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
720554005265	Protein of unknown function (DUF3766); Region: DUF3766; cl11797
720554005266	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK09618
720554005267	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
720554005268	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
720554005269	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554005270	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554005271	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554005272	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
720554005273	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
720554005274	flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497
720554005275	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
720554005276	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
720554005277	Walker A motif/ATP binding site; other site
720554005278	Walker B motif; other site
720554005279	flagellar assembly protein H; Validated; Region: fliH; PRK06669
720554005280	Flagellar assembly protein FliH; Region: FliH; pfam02108
720554005281	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
720554005282	FliG C-terminal domain; Region: FliG_C; pfam01706
720554005283	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
720554005284	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
720554005285	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
720554005286	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
720554005287	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
720554005288	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
720554005289	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
720554005290	Flagellar basal body protein [Cell motility and secretion]; Region: FlgB; COG1815
720554005291	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
720554005292	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
720554005293	Glucose inhibited division protein A; Region: GIDA; pfam01134
720554005294	DNA topoisomerase I; Validated; Region: PRK05582
720554005295	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
720554005296	active site
720554005297	interdomain interaction site; other site
720554005298	putative metal-binding site [ion binding]; other site
720554005299	nucleotide binding site [chemical binding]; other site
720554005300	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
720554005301	domain I; other site
720554005302	DNA binding groove [nucleotide binding]
720554005303	phosphate binding site [ion binding]; other site
720554005304	domain II; other site
720554005305	domain III; other site
720554005306	nucleotide binding site [chemical binding]; other site
720554005307	catalytic site [active]
720554005308	domain IV; other site
720554005309	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
720554005310	DNA protecting protein DprA; Region: dprA; TIGR00732
720554005311	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
720554005312	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
720554005313	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
720554005314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554005315	Walker A motif; other site
720554005316	ATP binding site [chemical binding]; other site
720554005317	Walker B motif; other site
720554005318	arginine finger; other site
720554005319	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
720554005320	endoglucanase; Region: PLN02308
720554005321	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554005322	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005323	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005324	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
720554005325	active site
720554005326	catalytic motif [active]
720554005327	Zn binding site [ion binding]; other site
720554005328	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554005329	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554005330	dockerin binding interface; other site
720554005331	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
720554005332	Sulfatase; Region: Sulfatase; pfam00884
720554005333	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
720554005334	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
720554005335	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005336	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005337	potassium/proton antiporter; Reviewed; Region: PRK05326
720554005338	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
720554005339	TrkA-C domain; Region: TrkA_C; pfam02080
720554005340	TrkA-C domain; Region: TrkA_C; pfam02080
720554005341	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
720554005342	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
720554005343	catalytic core [active]
720554005344	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
720554005345	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
720554005346	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG2; TIGR02495
720554005347	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554005348	FeS/SAM binding site; other site
720554005349	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK08270
720554005350	ATP cone domain; Region: ATP-cone; pfam03477
720554005351	Class III ribonucleotide reductase; Region: RNR_III; cd01675
720554005352	effector binding site; other site
720554005353	active site
720554005354	Zn binding site [ion binding]; other site
720554005355	glycine loop; other site
720554005356	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554005357	active site
720554005358	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
720554005359	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
720554005360	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
720554005361	substrate binding pocket [chemical binding]; other site
720554005362	dimer interface [polypeptide binding]; other site
720554005363	inhibitor binding site; inhibition site
720554005364	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
720554005365	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
720554005366	B12 binding site [chemical binding]; other site
720554005367	cobalt ligand [ion binding]; other site
720554005368	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
720554005369	Coat F domain; Region: Coat_F; pfam07875
720554005370	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
720554005371	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
720554005372	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182
720554005373	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
720554005374	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
720554005375	active site
720554005376	dimer interface [polypeptide binding]; other site
720554005377	metal binding site [ion binding]; metal-binding site
720554005378	DivIVA protein; Region: DivIVA; pfam05103
720554005379	DivIVA domain; Region: DivI1A_domain; TIGR03544
720554005380	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
720554005381	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554005382	RNA binding surface [nucleotide binding]; other site
720554005383	YGGT family; Region: YGGT; pfam02325
720554005384	Protein of unknown function (DUF552); Region: DUF552; pfam04472
720554005385	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
720554005386	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
720554005387	catalytic residue [active]
720554005388	HlyD family secretion protein; Region: HlyD_2; pfam12700
720554005389	putative membrane fusion protein; Region: TIGR02828
720554005390	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
720554005391	Aluminium resistance protein; Region: Alum_res; pfam06838
720554005392	maltodextrin glucosidase; Provisional; Region: PRK10785
720554005393	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
720554005394	homodimer interface [polypeptide binding]; other site
720554005395	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
720554005396	active site
720554005397	homodimer interface [polypeptide binding]; other site
720554005398	catalytic site [active]
720554005399	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
720554005400	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
720554005401	active site
720554005402	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
720554005403	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg1; cd04764
720554005404	DNA binding residues [nucleotide binding]
720554005405	1,3-beta-glucan synthase component; Region: Glucan_synthase; pfam02364
720554005406	Penicillinase repressor; Region: Pencillinase_R; pfam03965
720554005407	Response regulator receiver domain; Region: Response_reg; pfam00072
720554005408	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005409	active site
720554005410	phosphorylation site [posttranslational modification]
720554005411	intermolecular recognition site; other site
720554005412	dimerization interface [polypeptide binding]; other site
720554005413	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
720554005414	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554005415	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
720554005416	putative active site [active]
720554005417	heme pocket [chemical binding]; other site
720554005418	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554005419	putative active site [active]
720554005420	heme pocket [chemical binding]; other site
720554005421	PAS domain S-box; Region: sensory_box; TIGR00229
720554005422	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
720554005423	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
720554005424	putative active site [active]
720554005425	heme pocket [chemical binding]; other site
720554005426	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554005427	dimer interface [polypeptide binding]; other site
720554005428	phosphorylation site [posttranslational modification]
720554005429	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554005430	ATP binding site [chemical binding]; other site
720554005431	Mg2+ binding site [ion binding]; other site
720554005432	G-X-G motif; other site
720554005433	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
720554005434	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005435	active site
720554005436	phosphorylation site [posttranslational modification]
720554005437	intermolecular recognition site; other site
720554005438	dimerization interface [polypeptide binding]; other site
720554005439	CheB methylesterase; Region: CheB_methylest; pfam01339
720554005440	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
720554005441	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
720554005442	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
720554005443	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
720554005444	putative CheA interaction surface; other site
720554005445	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
720554005446	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
720554005447	putative binding surface; other site
720554005448	active site
720554005449	P2 response regulator binding domain; Region: P2; pfam07194
720554005450	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
720554005451	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554005452	ATP binding site [chemical binding]; other site
720554005453	Mg2+ binding site [ion binding]; other site
720554005454	G-X-G motif; other site
720554005455	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
720554005456	Response regulator receiver domain; Region: Response_reg; pfam00072
720554005457	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005458	active site
720554005459	phosphorylation site [posttranslational modification]
720554005460	intermolecular recognition site; other site
720554005461	dimerization interface [polypeptide binding]; other site
720554005462	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
720554005463	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005464	active site
720554005465	phosphorylation site [posttranslational modification]
720554005466	intermolecular recognition site; other site
720554005467	dimerization interface [polypeptide binding]; other site
720554005468	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
720554005469	stage IV sporulation protein B; Region: spore_IV_B; TIGR02860
720554005470	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
720554005471	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
720554005472	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
720554005473	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
720554005474	Walker A/P-loop; other site
720554005475	ATP binding site [chemical binding]; other site
720554005476	Q-loop/lid; other site
720554005477	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
720554005478	ABC transporter signature motif; other site
720554005479	Walker B; other site
720554005480	D-loop; other site
720554005481	H-loop/switch region; other site
720554005482	arginine repressor; Provisional; Region: argR; PRK00441
720554005483	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
720554005484	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
720554005485	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
720554005486	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
720554005487	TPR repeat; Region: TPR_11; pfam13414
720554005488	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554005489	binding surface
720554005490	TPR motif; other site
720554005491	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554005492	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
720554005493	TPR motif; other site
720554005494	binding surface
720554005495	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
720554005496	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
720554005497	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
720554005498	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
720554005499	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
720554005500	Fatty acid synthesis protein; Region: FA_synthesis; cl17261
720554005501	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554005502	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554005503	Src Homology 3 domain superfamily; Region: SH3; cl17036
720554005504	peptide ligand binding site [polypeptide binding]; other site
720554005505	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
720554005506	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554005507	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554005508	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005509	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005510	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005511	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005512	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005513	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005514	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005515	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005516	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005517	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005518	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005519	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005520	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005521	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554005522	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005523	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554005524	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
720554005525	FtsX-like permease family; Region: FtsX; pfam02687
720554005526	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
720554005527	FtsX-like permease family; Region: FtsX; pfam02687
720554005528	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554005529	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554005530	Walker A/P-loop; other site
720554005531	ATP binding site [chemical binding]; other site
720554005532	Q-loop/lid; other site
720554005533	ABC transporter signature motif; other site
720554005534	Walker B; other site
720554005535	D-loop; other site
720554005536	H-loop/switch region; other site
720554005537	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554005538	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554005539	dimer interface [polypeptide binding]; other site
720554005540	phosphorylation site [posttranslational modification]
720554005541	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554005542	ATP binding site [chemical binding]; other site
720554005543	Mg2+ binding site [ion binding]; other site
720554005544	G-X-G motif; other site
720554005545	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554005546	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005547	active site
720554005548	phosphorylation site [posttranslational modification]
720554005549	intermolecular recognition site; other site
720554005550	dimerization interface [polypeptide binding]; other site
720554005551	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554005552	DNA binding site [nucleotide binding]
720554005553	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554005554	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005555	active site
720554005556	phosphorylation site [posttranslational modification]
720554005557	intermolecular recognition site; other site
720554005558	dimerization interface [polypeptide binding]; other site
720554005559	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554005560	DNA binding site [nucleotide binding]
720554005561	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554005562	dimerization interface [polypeptide binding]; other site
720554005563	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
720554005564	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554005565	dimer interface [polypeptide binding]; other site
720554005566	phosphorylation site [posttranslational modification]
720554005567	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554005568	ATP binding site [chemical binding]; other site
720554005569	Mg2+ binding site [ion binding]; other site
720554005570	G-X-G motif; other site
720554005571	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
720554005572	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554005573	RNA binding surface [nucleotide binding]; other site
720554005574	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
720554005575	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
720554005576	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
720554005577	TPP-binding site; other site
720554005578	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
720554005579	PYR/PP interface [polypeptide binding]; other site
720554005580	dimer interface [polypeptide binding]; other site
720554005581	TPP binding site [chemical binding]; other site
720554005582	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554005583	Divergent PAP2 family; Region: DUF212; pfam02681
720554005584	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
720554005585	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
720554005586	substrate binding pocket [chemical binding]; other site
720554005587	chain length determination region; other site
720554005588	substrate-Mg2+ binding site; other site
720554005589	catalytic residues [active]
720554005590	aspartate-rich region 1; other site
720554005591	active site lid residues [active]
720554005592	aspartate-rich region 2; other site
720554005593	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
720554005594	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
720554005595	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
720554005596	generic binding surface II; other site
720554005597	generic binding surface I; other site
720554005598	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
720554005599	putative RNA binding site [nucleotide binding]; other site
720554005600	Small integral membrane protein (DUF2273); Region: DUF2273; pfam10031
720554005601	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
720554005602	Asp23 family; Region: Asp23; pfam03780
720554005603	Asp23 family; Region: Asp23; pfam03780
720554005604	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
720554005605	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
720554005606	Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; pfam09581
720554005607	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; pfam09546
720554005608	stage III sporulation protein AD; Region: spore_III_AD; TIGR02849
720554005609	stage III sporulation protein AC; Region: spore_III_AC; TIGR02848
720554005610	Stage III sporulation protein AB (spore_III_AB); Region: Spore_III_AB; pfam09548
720554005611	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
720554005612	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
720554005613	Walker A motif; other site
720554005614	ATP binding site [chemical binding]; other site
720554005615	uracil transporter; Provisional; Region: PRK10720
720554005616	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554005617	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554005618	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554005619	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554005620	metal binding site [ion binding]; metal-binding site
720554005621	active site
720554005622	I-site; other site
720554005623	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554005624	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554005625	Zn2+ binding site [ion binding]; other site
720554005626	Mg2+ binding site [ion binding]; other site
720554005627	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
720554005628	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
720554005629	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
720554005630	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
720554005631	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
720554005632	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
720554005633	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
720554005634	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554005635	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554005636	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554005637	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554005638	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
720554005639	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005640	dimer interface [polypeptide binding]; other site
720554005641	ABC-ATPase subunit interface; other site
720554005642	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
720554005643	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005644	dimer interface [polypeptide binding]; other site
720554005645	conserved gate region; other site
720554005646	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
720554005647	ABC-ATPase subunit interface; other site
720554005648	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
720554005649	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
720554005650	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554005651	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554005652	Walker A/P-loop; other site
720554005653	ATP binding site [chemical binding]; other site
720554005654	Q-loop/lid; other site
720554005655	ABC transporter signature motif; other site
720554005656	Walker B; other site
720554005657	D-loop; other site
720554005658	H-loop/switch region; other site
720554005659	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cd06462
720554005660	Catalytic site [active]
720554005661	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
720554005662	SynChlorMet cassette protein ScmC; Region: SCM_chp_ScmC; TIGR04249
720554005663	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
720554005664	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
720554005665	putative efflux protein, MATE family; Region: matE; TIGR00797
720554005666	Protein of unknown function (DUF3237); Region: DUF3237; pfam11578
720554005667	Protein of unknown function (DUF3237); Region: DUF3237; cl07905
720554005668	SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833
720554005669	active site
720554005670	catalytic triad [active]
720554005671	oxyanion hole [active]
720554005672	SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833
720554005673	active site
720554005674	catalytic triad [active]
720554005675	oxyanion hole [active]
720554005676	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554005677	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554005678	Alpha-L-arabinofuranosidase B (ABFB); Region: AbfB; pfam05270
720554005679	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554005680	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005681	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
720554005682	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
720554005683	active site
720554005684	catalytic site [active]
720554005685	metal binding site [ion binding]; metal-binding site
720554005686	dimer interface [polypeptide binding]; other site
720554005687	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
720554005688	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554005689	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554005690	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554005691	lipoic acid synthase; Region: PLN02428
720554005692	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554005693	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554005694	Protein of unknown function DUF54; Region: DUF54; cl00585
720554005695	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
720554005696	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cd00688
720554005697	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
720554005698	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
720554005699	von Willebrand factor (vWF) type A domain; Region: VWA; smart00327
720554005700	S-layer homology domain; Region: SLH; pfam00395
720554005701	S-layer homology domain; Region: SLH; pfam00395
720554005702	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
720554005703	Uncharacterized conserved protein [Function unknown]; Region: COG0327
720554005704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
720554005705	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
720554005706	Uncharacterized conserved protein [Function unknown]; Region: COG0327
720554005707	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
720554005708	Family of unknown function (DUF633); Region: DUF633; pfam04816
720554005709	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
720554005710	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
720554005711	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
720554005712	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
720554005713	ligand binding site [chemical binding]; other site
720554005714	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
720554005715	Uncharacterized conserved protein [Function unknown]; Region: COG1633
720554005716	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
720554005717	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
720554005718	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
720554005719	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005720	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
720554005721	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554005722	DNA binding residues [nucleotide binding]
720554005723	DNA primase; Validated; Region: dnaG; PRK05667
720554005724	CHC2 zinc finger; Region: zf-CHC2; pfam01807
720554005725	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
720554005726	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
720554005727	active site
720554005728	metal binding site [ion binding]; metal-binding site
720554005729	interdomain interaction site; other site
720554005730	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
720554005731	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
720554005732	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554005733	Zn2+ binding site [ion binding]; other site
720554005734	Mg2+ binding site [ion binding]; other site
720554005735	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
720554005736	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554005737	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554005738	Zn2+ binding site [ion binding]; other site
720554005739	Mg2+ binding site [ion binding]; other site
720554005740	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
720554005741	tetramerization interface [polypeptide binding]; other site
720554005742	active site
720554005743	pantoate--beta-alanine ligase; Region: panC; TIGR00018
720554005744	Pantoate-beta-alanine ligase; Region: PanC; cd00560
720554005745	active site
720554005746	ATP-binding site [chemical binding]; other site
720554005747	pantoate-binding site; other site
720554005748	HXXH motif; other site
720554005749	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
720554005750	oligomerization interface [polypeptide binding]; other site
720554005751	active site
720554005752	metal binding site [ion binding]; metal-binding site
720554005753	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
720554005754	Protein export membrane protein; Region: SecD_SecF; pfam02355
720554005755	protein-export membrane protein SecD; Region: secD; TIGR01129
720554005756	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
720554005757	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554005758	Zn2+ binding site [ion binding]; other site
720554005759	Mg2+ binding site [ion binding]; other site
720554005760	SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974
720554005761	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554005762	FeS/SAM binding site; other site
720554005763	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
720554005764	Protein of unknown function (DUF4001); Region: DUF4001; pfam13165
720554005765	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
720554005766	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554005767	RNA binding surface [nucleotide binding]; other site
720554005768	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
720554005769	active site
720554005770	lipoprotein signal peptidase; Provisional; Region: PRK14787
720554005771	lipoprotein signal peptidase; Provisional; Region: PRK14791
720554005772	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
720554005773	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554005774	Zn2+ binding site [ion binding]; other site
720554005775	Mg2+ binding site [ion binding]; other site
720554005776	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
720554005777	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554005778	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005779	dimer interface [polypeptide binding]; other site
720554005780	ABC-ATPase subunit interface; other site
720554005781	putative PBP binding loops; other site
720554005782	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554005783	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005784	dimer interface [polypeptide binding]; other site
720554005785	conserved gate region; other site
720554005786	putative PBP binding loops; other site
720554005787	ABC-ATPase subunit interface; other site
720554005788	Uncharacterized small protein (DUF2292); Region: DUF2292; pfam10055
720554005789	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554005790	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554005791	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554005792	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554005793	nitrogenase reductase; Reviewed; Region: nifH; PRK13235
720554005794	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
720554005795	Nucleotide-binding sites [chemical binding]; other site
720554005796	Walker A motif; other site
720554005797	Switch I region of nucleotide binding site; other site
720554005798	Fe4S4 binding sites [ion binding]; other site
720554005799	Switch II region of nucleotide binding site; other site
720554005800	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
720554005801	NMT1/THI5 like; Region: NMT1; pfam09084
720554005802	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
720554005803	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554005804	substrate binding pocket [chemical binding]; other site
720554005805	membrane-bound complex binding site; other site
720554005806	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554005807	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005808	dimer interface [polypeptide binding]; other site
720554005809	conserved gate region; other site
720554005810	putative PBP binding loops; other site
720554005811	ABC-ATPase subunit interface; other site
720554005812	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554005813	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554005814	dimer interface [polypeptide binding]; other site
720554005815	conserved gate region; other site
720554005816	putative PBP binding loops; other site
720554005817	ABC-ATPase subunit interface; other site
720554005818	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
720554005819	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
720554005820	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
720554005821	peptide binding site [polypeptide binding]; other site
720554005822	dimer interface [polypeptide binding]; other site
720554005823	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
720554005824	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
720554005825	plasma-membrane calcium-translocating P-type ATPase; Region: ATPase-IIB_Ca; TIGR01517
720554005826	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
720554005827	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
720554005828	PilZ domain; Region: PilZ; pfam07238
720554005829	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
720554005830	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
720554005831	active site
720554005832	HIGH motif; other site
720554005833	nucleotide binding site [chemical binding]; other site
720554005834	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
720554005835	KMSKS motif; other site
720554005836	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
720554005837	Predicted membrane protein [Function unknown]; Region: COG2246
720554005838	GtrA-like protein; Region: GtrA; pfam04138
720554005839	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
720554005840	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
720554005841	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
720554005842	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
720554005843	active site
720554005844	short chain dehydrogenase; Provisional; Region: PRK06924
720554005845	sepiapterin reductase (SPR)-like, classical (c) SDRs; Region: SPR-like_SDR_c; cd05367
720554005846	NADP binding site [chemical binding]; other site
720554005847	homodimer interface [polypeptide binding]; other site
720554005848	active site
720554005849	?-D-glucose-1-phosphatase; Provisional; Region: PRK09456
720554005850	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
720554005851	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
720554005852	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
720554005853	YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in...; Region: Rieske_YhfW_C; cd03477
720554005854	[2Fe-2S] cluster binding site [ion binding]; other site
720554005855	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554005856	Zn2+ binding site [ion binding]; other site
720554005857	Mg2+ binding site [ion binding]; other site
720554005858	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
720554005859	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
720554005860	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cd09637
720554005861	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
720554005862	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cd09634
720554005863	CRISPR-associated protein (Cas_Cas02710); Region: Cas_Cas02710; pfam09670
720554005864	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09747
720554005865	CRISPR-associated (Cas) DxTHG family; Region: Cas_DxTHG; pfam09455
720554005866	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09732
720554005867	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cl17439
720554005868	CRISPR-associated protein; Region: TIGR03986
720554005869	CRISPR-associated protein, TIGR03984 family; Region: TIGR03984
720554005870	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cd09726
720554005871	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cd09726
720554005872	CRISPR/Cas system-associated RAMP superfamily protein Csx10; Region: Csx10; cl17558
720554005873	CRISPR/Cas system-associated RAMP superfamily protein Csx10; Region: Csx10; cl17558
720554005874	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cd09726
720554005875	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
720554005876	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
720554005877	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
720554005878	CRISPR-associated protein Cas5, subtype I-B/HMARI; Region: cas_Cas5h; TIGR02592
720554005879	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cl12040
720554005880	Family of unknown function (DUF694); Region: DUF694; pfam05107
720554005881	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cd09730
720554005882	Protein of unknown function DUF115; Region: MAF_flag10; pfam01973
720554005883	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
720554005884	ATP cone domain; Region: ATP-cone; pfam03477
720554005885	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
720554005886	sporulation sigma factor SigG; Reviewed; Region: PRK08215
720554005887	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005888	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
720554005889	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554005890	DNA binding residues [nucleotide binding]
720554005891	sporulation sigma factor SigE; Reviewed; Region: PRK08301
720554005892	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554005893	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554005894	DNA binding residues [nucleotide binding]
720554005895	Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419
720554005896	sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854
720554005897	cell division protein FtsZ; Validated; Region: PRK09330
720554005898	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
720554005899	nucleotide binding site [chemical binding]; other site
720554005900	SulA interaction site; other site
720554005901	cell division protein FtsA; Region: ftsA; TIGR01174
720554005902	Cell division protein FtsA; Region: FtsA; smart00842
720554005903	Cell division protein FtsA; Region: FtsA; pfam14450
720554005904	Protein of unknown function (DUF1290); Region: DUF1290; pfam06947
720554005905	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
720554005906	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
720554005907	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554005908	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
720554005909	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
720554005910	catalytic triad [active]
720554005911	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554005912	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554005913	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554005914	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
720554005915	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
720554005916	putative ligand binding site [chemical binding]; other site
720554005917	DOMON-like type 9 carbohydrate binding module of xylanases; Region: CBM9_like_1; cd00005
720554005918	Ca binding site [ion binding]; other site
720554005919	carbohydrate binding site [chemical binding]; other site
720554005920	hypothetical protein; Provisional; Region: PRK06851
720554005921	prolyl-tRNA synthetase; Provisional; Region: PRK09194
720554005922	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
720554005923	dimer interface [polypeptide binding]; other site
720554005924	motif 1; other site
720554005925	active site
720554005926	motif 2; other site
720554005927	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
720554005928	putative deacylase active site [active]
720554005929	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
720554005930	active site
720554005931	motif 3; other site
720554005932	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
720554005933	anticodon binding site; other site
720554005934	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
720554005935	Iron-containing alcohol dehydrogenase; Region: Fe-ADH8; cd08186
720554005936	putative active site [active]
720554005937	metal binding site [ion binding]; metal-binding site
720554005938	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
720554005939	predicted active site [active]
720554005940	catalytic triad [active]
720554005941	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
720554005942	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
720554005943	active site
720554005944	multimer interface [polypeptide binding]; other site
720554005945	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
720554005946	DNA-binding site [nucleotide binding]; DNA binding site
720554005947	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
720554005948	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554005949	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554005950	homodimer interface [polypeptide binding]; other site
720554005951	catalytic residue [active]
720554005952	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
720554005953	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
720554005954	dimer interface [polypeptide binding]; other site
720554005955	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554005956	catalytic residue [active]
720554005957	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
720554005958	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
720554005959	homodimer interface [polypeptide binding]; other site
720554005960	substrate-cofactor binding pocket; other site
720554005961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554005962	catalytic residue [active]
720554005963	Predicted transcriptional regulator [Transcription]; Region: COG1959
720554005964	Transcriptional regulator; Region: Rrf2; cl17282
720554005965	Predicted transcriptional regulator [Transcription]; Region: COG1959
720554005966	Transcriptional regulator; Region: Rrf2; cl17282
720554005967	Homoserine O-succinyltransferase; Region: HTS; pfam04204
720554005968	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
720554005969	proposed active site lysine [active]
720554005970	conserved cys residue [active]
720554005971	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554005972	metal-binding site [ion binding]
720554005973	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
720554005974	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554005975	metal-binding site [ion binding]
720554005976	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
720554005977	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554005978	metal-binding site [ion binding]
720554005979	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
720554005980	Soluble P-type ATPase [General function prediction only]; Region: COG4087
720554005981	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
720554005982	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554005983	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554005984	dimerization interface [polypeptide binding]; other site
720554005985	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554005986	dimer interface [polypeptide binding]; other site
720554005987	phosphorylation site [posttranslational modification]
720554005988	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554005989	ATP binding site [chemical binding]; other site
720554005990	Mg2+ binding site [ion binding]; other site
720554005991	G-X-G motif; other site
720554005992	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554005993	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554005994	active site
720554005995	phosphorylation site [posttranslational modification]
720554005996	intermolecular recognition site; other site
720554005997	dimerization interface [polypeptide binding]; other site
720554005998	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554005999	DNA binding site [nucleotide binding]
720554006000	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554006001	metal-binding site [ion binding]
720554006002	Family description; Region: DsbD_2; pfam13386
720554006003	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
720554006004	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554006005	Resolvase, N terminal domain; Region: Resolvase; smart00857
720554006006	catalytic residues [active]
720554006007	catalytic nucleophile [active]
720554006008	Recombinase; Region: Recombinase; pfam07508
720554006009	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554006010	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554006011	Walker A motif; other site
720554006012	ATP binding site [chemical binding]; other site
720554006013	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
720554006014	active site
720554006015	Ap6A binding site [chemical binding]; other site
720554006016	nudix motif; other site
720554006017	metal binding site [ion binding]; metal-binding site
720554006018	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
720554006019	Putative catalytic domain, repeat 1, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_1; cd09154
720554006020	putative active site [active]
720554006021	catalytic site [active]
720554006022	Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_2; cd09160
720554006023	putative active site [active]
720554006024	catalytic site [active]
720554006025	RNA polymerase sigma-70 factor, TIGR02952 family; Region: Sig70_famx2
720554006026	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554006027	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554006028	DNA binding residues [nucleotide binding]
720554006029	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
720554006030	DNA polymerase IV; Reviewed; Region: PRK03103
720554006031	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
720554006032	active site
720554006033	DNA binding site [nucleotide binding]
720554006034	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
720554006035	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
720554006036	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
720554006037	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
720554006038	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
720554006039	endoglucanase; Region: PLN02308
720554006040	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554006041	Cellulose binding domain; Region: CBM_3; smart01067
720554006042	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
720554006043	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
720554006044	active site
720554006045	6-phosphofructokinase; Provisional; Region: PRK03202
720554006046	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
720554006047	active site
720554006048	ADP/pyrophosphate binding site [chemical binding]; other site
720554006049	dimerization interface [polypeptide binding]; other site
720554006050	allosteric effector site; other site
720554006051	fructose-1,6-bisphosphate binding site; other site
720554006052	transcription attenuation protein MtrB; Provisional; Region: PRK13251
720554006053	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826
720554006054	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
720554006055	active site
720554006056	PHP Thumb interface [polypeptide binding]; other site
720554006057	metal binding site [ion binding]; metal-binding site
720554006058	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
720554006059	generic binding surface II; other site
720554006060	generic binding surface I; other site
720554006061	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
720554006062	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
720554006063	active site
720554006064	substrate binding site [chemical binding]; other site
720554006065	metal binding site [ion binding]; metal-binding site
720554006066	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554006067	MULE transposase domain; Region: MULE; pfam10551
720554006068	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554006069	non-specific DNA binding site [nucleotide binding]; other site
720554006070	salt bridge; other site
720554006071	sequence-specific DNA binding site [nucleotide binding]; other site
720554006072	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
720554006073	GEMM cis-regulatory element
720554006074	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
720554006075	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554006076	active site
720554006077	phosphorylation site [posttranslational modification]
720554006078	intermolecular recognition site; other site
720554006079	dimerization interface [polypeptide binding]; other site
720554006080	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
720554006081	DNA binding residues [nucleotide binding]
720554006082	dimerization interface [polypeptide binding]; other site
720554006083	Sensor protein DegS; Region: DegS; pfam05384
720554006084	Histidine kinase; Region: HisKA_3; pfam07730
720554006085	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
720554006086	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554006087	ATP binding site [chemical binding]; other site
720554006088	Mg2+ binding site [ion binding]; other site
720554006089	G-X-G motif; other site
720554006090	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
720554006091	Nucleoside recognition; Region: Gate; pfam07670
720554006092	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
720554006093	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
720554006094	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
720554006095	active site
720554006096	(T/H)XGH motif; other site
720554006097	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
720554006098	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554006099	S-adenosylmethionine binding site [chemical binding]; other site
720554006100	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
720554006101	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
720554006102	generic binding surface II; other site
720554006103	ssDNA binding site; other site
720554006104	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554006105	ATP binding site [chemical binding]; other site
720554006106	putative Mg++ binding site [ion binding]; other site
720554006107	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554006108	nucleotide binding region [chemical binding]; other site
720554006109	ATP-binding site [chemical binding]; other site
720554006110	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
720554006111	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
720554006112	GAF domain; Region: GAF_3; pfam13492
720554006113	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554006114	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554006115	metal binding site [ion binding]; metal-binding site
720554006116	active site
720554006117	I-site; other site
720554006118	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
720554006119	Cell division protein FtsA; Region: FtsA; smart00842
720554006120	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
720554006121	nucleotide binding site [chemical binding]; other site
720554006122	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
720554006123	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
720554006124	minor groove reading motif; other site
720554006125	helix-hairpin-helix signature motif; other site
720554006126	substrate binding pocket [chemical binding]; other site
720554006127	active site
720554006128	glycogen synthase; Provisional; Region: glgA; PRK00654
720554006129	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
720554006130	ADP-binding pocket [chemical binding]; other site
720554006131	homodimer interface [polypeptide binding]; other site
720554006132	GAF domain; Region: GAF_3; pfam13492
720554006133	GAF domain; Region: GAF_2; pfam13185
720554006134	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554006135	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554006136	Zn2+ binding site [ion binding]; other site
720554006137	Mg2+ binding site [ion binding]; other site
720554006138	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
720554006139	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
720554006140	protein binding site [polypeptide binding]; other site
720554006141	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554006142	dimerization interface [polypeptide binding]; other site
720554006143	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554006144	dimer interface [polypeptide binding]; other site
720554006145	phosphorylation site [posttranslational modification]
720554006146	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554006147	ATP binding site [chemical binding]; other site
720554006148	Mg2+ binding site [ion binding]; other site
720554006149	G-X-G motif; other site
720554006150	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554006151	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554006152	active site
720554006153	phosphorylation site [posttranslational modification]
720554006154	intermolecular recognition site; other site
720554006155	dimerization interface [polypeptide binding]; other site
720554006156	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554006157	DNA binding site [nucleotide binding]
720554006158	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
720554006159	active site
720554006160	cofactor-independent phosphoglycerate mutase; Provisional; Region: PRK04200
720554006161	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: PhosphMutase; cl17294
720554006162	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554006163	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554006164	Zn2+ binding site [ion binding]; other site
720554006165	Mg2+ binding site [ion binding]; other site
720554006166	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
720554006167	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
720554006168	DNA binding residues [nucleotide binding]
720554006169	dimer interface [polypeptide binding]; other site
720554006170	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
720554006171	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
720554006172	DNA polymerase IV; Reviewed; Region: PRK03103
720554006173	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
720554006174	active site
720554006175	DNA binding site [nucleotide binding]
720554006176	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
720554006177	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554006178	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006179	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
720554006180	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
720554006181	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
720554006182	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
720554006183	Walker A/P-loop; other site
720554006184	ATP binding site [chemical binding]; other site
720554006185	Q-loop/lid; other site
720554006186	ABC transporter signature motif; other site
720554006187	Walker B; other site
720554006188	D-loop; other site
720554006189	H-loop/switch region; other site
720554006190	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554006191	dimer interface [polypeptide binding]; other site
720554006192	conserved gate region; other site
720554006193	putative PBP binding loops; other site
720554006194	ABC-ATPase subunit interface; other site
720554006195	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554006196	hinge residues; other site
720554006197	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
720554006198	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554006199	substrate binding pocket [chemical binding]; other site
720554006200	membrane-bound complex binding site; other site
720554006201	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006202	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
720554006203	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554006204	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
720554006205	catalytic residues [active]
720554006206	catalytic nucleophile [active]
720554006207	Recombinase; Region: Recombinase; pfam07508
720554006208	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554006209	CAAX protease self-immunity; Region: Abi; pfam02517
720554006210	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
720554006211	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
720554006212	Predicted membrane protein (DUF2085); Region: DUF2085; pfam09858
720554006213	Double zinc ribbon; Region: DZR; pfam12773
720554006214	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
720554006215	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
720554006216	5S rRNA interface [nucleotide binding]; other site
720554006217	CTC domain interface [polypeptide binding]; other site
720554006218	L16 interface [polypeptide binding]; other site
720554006219	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
720554006220	dinuclear metal binding motif [ion binding]; other site
720554006221	hypothetical protein; Provisional; Region: PRK13670
720554006222	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
720554006223	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
720554006224	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554006225	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
720554006226	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554006227	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
720554006228	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
720554006229	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
720554006230	putative active site [active]
720554006231	PhoH-like protein; Region: PhoH; pfam02562
720554006232	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
720554006233	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
720554006234	nitrogenase iron protein; Region: nifH; TIGR01287
720554006235	Nucleotide-binding sites [chemical binding]; other site
720554006236	Walker A motif; other site
720554006237	Switch I region of nucleotide binding site; other site
720554006238	Fe4S4 binding sites [ion binding]; other site
720554006239	Switch II region of nucleotide binding site; other site
720554006240	Family description; Region: DsbD_2; pfam13386
720554006241	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
720554006242	Plastocyanin domain containing protein [General function prediction only]; Region: COG4633
720554006243	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
720554006244	S-layer homology domain; Region: SLH; pfam00395
720554006245	S-layer homology domain; Region: SLH; pfam00395
720554006246	S-layer homology domain; Region: SLH; pfam00395
720554006247	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
720554006248	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
720554006249	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
720554006250	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554006251	metal-binding site [ion binding]
720554006252	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
720554006253	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554006254	motif II; other site
720554006255	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
720554006256	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
720554006257	Walker A/P-loop; other site
720554006258	ATP binding site [chemical binding]; other site
720554006259	Q-loop/lid; other site
720554006260	ABC transporter signature motif; other site
720554006261	Walker B; other site
720554006262	D-loop; other site
720554006263	H-loop/switch region; other site
720554006264	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
720554006265	NMT1/THI5 like; Region: NMT1; pfam09084
720554006266	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554006267	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554006268	dimer interface [polypeptide binding]; other site
720554006269	conserved gate region; other site
720554006270	putative PBP binding loops; other site
720554006271	ABC-ATPase subunit interface; other site
720554006272	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554006273	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554006274	dimer interface [polypeptide binding]; other site
720554006275	ABC-ATPase subunit interface; other site
720554006276	putative PBP binding loops; other site
720554006277	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554006278	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554006279	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554006280	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554006281	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
720554006282	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
720554006283	methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370
720554006284	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
720554006285	B12 binding site [chemical binding]; other site
720554006286	cobalt ligand [ion binding]; other site
720554006287	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
720554006288	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
720554006289	dimer interface [polypeptide binding]; other site
720554006290	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554006291	catalytic residue [active]
720554006292	Nitroreductase family; Region: Nitroreductase; pfam00881
720554006293	FMN binding site [chemical binding]; other site
720554006294	dimer interface [polypeptide binding]; other site
720554006295	nitrogenase cofactor biosynthesis protein NifB; Region: nifB; TIGR01290
720554006296	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554006297	FeS/SAM binding site; other site
720554006298	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cl00252
720554006299	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cd00562
720554006300	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
720554006301	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
720554006302	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; cl01811
720554006303	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554006304	MULE transposase domain; Region: MULE; pfam10551
720554006305	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554006306	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006307	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554006308	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554006309	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554006310	transposase; Provisional; Region: PRK06526
720554006311	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554006312	Walker A motif; other site
720554006313	ATP binding site [chemical binding]; other site
720554006314	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554006315	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554006316	putative Zn2+ binding site [ion binding]; other site
720554006317	putative DNA binding site [nucleotide binding]; other site
720554006318	Integrase core domain; Region: rve; pfam00665
720554006319	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006320	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554006321	Transposase; Region: HTH_Tnp_1; cl17663
720554006322	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554006323	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554006324	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554006325	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554006326	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
720554006327	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554006328	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006329	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554006330	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554006331	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006332	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554006333	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554006334	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006335	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554006336	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554006337	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006338	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554006339	Transposase; Region: HTH_Tnp_1; cl17663
720554006340	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006341	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554006342	Transposase; Region: HTH_Tnp_1; cl17663
720554006343	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cl17442
720554006344	thioester formation/cholesterol transfer; other site
720554006345	protein-splicing catalytic site; other site
720554006346	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554006347	Hint domain; Region: Hint_2; pfam13403
720554006348	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
720554006349	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554006350	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554006351	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006352	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554006353	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554006354	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554006355	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554006356	Transposase; Region: HTH_Tnp_1; cl17663
720554006357	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554006358	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554006359	protein-splicing catalytic site; other site
720554006360	thioester formation/cholesterol transfer; other site
720554006361	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554006362	The BURPS668_1122 family of deaminases; Region: Toxin-deaminase; pfam14424
720554006363	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006364	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554006365	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554006366	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554006367	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554006368	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554006369	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554006370	Interdomain contacts; other site
720554006371	Cytokine receptor motif; other site
720554006372	Bacterial SH3 domain; Region: SH3_3; pfam08239
720554006373	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554006374	RHS Repeat; Region: RHS_repeat; cl11982
720554006375	RHS Repeat; Region: RHS_repeat; pfam05593
720554006376	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554006377	RHS Repeat; Region: RHS_repeat; pfam05593
720554006378	RHS Repeat; Region: RHS_repeat; pfam05593
720554006379	RHS Repeat; Region: RHS_repeat; pfam05593
720554006380	RHS Repeat; Region: RHS_repeat; pfam05593
720554006381	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554006382	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
720554006383	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554006384	Putative zinc-finger; Region: zf-HC2; pfam13490
720554006385	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554006386	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554006387	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554006388	DNA binding residues [nucleotide binding]
720554006389	S-layer homology domain; Region: SLH; pfam00395
720554006390	S-layer homology domain; Region: SLH; pfam00395
720554006391	S-layer homology domain; Region: SLH; pfam00395
720554006392	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
720554006393	transposase/IS protein; Provisional; Region: PRK09183
720554006394	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554006395	Walker A motif; other site
720554006396	ATP binding site [chemical binding]; other site
720554006397	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
720554006398	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554006399	DNA-binding interface [nucleotide binding]; DNA binding site
720554006400	Integrase core domain; Region: rve; pfam00665
720554006401	Protein of unknown function (DUF3990); Region: DUF3990; pfam13151
720554006402	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
720554006403	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
720554006404	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554006405	FeS/SAM binding site; other site
720554006406	ribonuclease III; Reviewed; Region: rnc; PRK00102
720554006407	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
720554006408	dimerization interface [polypeptide binding]; other site
720554006409	active site
720554006410	metal binding site [ion binding]; metal-binding site
720554006411	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
720554006412	dsRNA binding site [nucleotide binding]; other site
720554006413	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
720554006414	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
720554006415	dimer interface [polypeptide binding]; other site
720554006416	active site
720554006417	acyl carrier protein; Provisional; Region: acpP; PRK00982
720554006418	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
720554006419	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
720554006420	NAD(P) binding site [chemical binding]; other site
720554006421	homotetramer interface [polypeptide binding]; other site
720554006422	homodimer interface [polypeptide binding]; other site
720554006423	active site
720554006424	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
720554006425	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
720554006426	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
720554006427	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
720554006428	dimer interface [polypeptide binding]; other site
720554006429	active site
720554006430	CoA binding pocket [chemical binding]; other site
720554006431	putative phosphate acyltransferase; Provisional; Region: PRK05331
720554006432	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
720554006433	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
720554006434	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
720554006435	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
720554006436	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
720554006437	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554006438	FeS/SAM binding site; other site
720554006439	PAC2 family; Region: PAC2; cl00847
720554006440	chromosome segregation protein; Provisional; Region: PRK03918
720554006441	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554006442	Walker A/P-loop; other site
720554006443	ATP binding site [chemical binding]; other site
720554006444	Rad50 zinc hook motif; Region: Rad50_zn_hook; pfam04423
720554006445	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
720554006446	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
720554006447	active site
720554006448	metal binding site [ion binding]; metal-binding site
720554006449	DNA binding site [nucleotide binding]
720554006450	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
720554006451	catalytic core [active]
720554006452	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
720554006453	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
720554006454	heterodimer interface [polypeptide binding]; other site
720554006455	active site
720554006456	FMN binding site [chemical binding]; other site
720554006457	homodimer interface [polypeptide binding]; other site
720554006458	substrate binding site [chemical binding]; other site
720554006459	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
720554006460	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
720554006461	FAD binding pocket [chemical binding]; other site
720554006462	FAD binding motif [chemical binding]; other site
720554006463	phosphate binding motif [ion binding]; other site
720554006464	beta-alpha-beta structure motif; other site
720554006465	NAD binding pocket [chemical binding]; other site
720554006466	Iron coordination center [ion binding]; other site
720554006467	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
720554006468	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
720554006469	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
720554006470	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
720554006471	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
720554006472	ATP-grasp domain; Region: ATP-grasp_4; cl17255
720554006473	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
720554006474	IMP binding site; other site
720554006475	dimer interface [polypeptide binding]; other site
720554006476	interdomain contacts; other site
720554006477	partial ornithine binding site; other site
720554006478	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
720554006479	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
720554006480	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
720554006481	catalytic site [active]
720554006482	subunit interface [polypeptide binding]; other site
720554006483	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
720554006484	active site
720554006485	dimer interface [polypeptide binding]; other site
720554006486	dihydroorotase; Validated; Region: pyrC; PRK09357
720554006487	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
720554006488	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
720554006489	active site
720554006490	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
720554006491	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
720554006492	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
720554006493	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
720554006494	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554006495	active site
720554006496	Protein of unknown function (DUF3792); Region: DUF3792; pfam12670
720554006497	Carbohydrate binding domain (family 25); Region: CBM_25; cl04060
720554006498	Preprotein translocase subunit; Region: YajC; pfam02699
720554006499	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
720554006500	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
720554006501	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
720554006502	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
720554006503	Stage II sporulation protein; Region: SpoIID; pfam08486
720554006504	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
720554006505	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
720554006506	dihydrodipicolinate synthase; Region: dapA; TIGR00674
720554006507	dimer interface [polypeptide binding]; other site
720554006508	active site
720554006509	catalytic residue [active]
720554006510	dihydrodipicolinate reductase; Provisional; Region: PRK00048
720554006511	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
720554006512	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
720554006513	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins; Region: ACT_AK-LysC-DapG-like_1; cd04891
720554006514	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923
720554006515	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
720554006516	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
720554006517	homodimer interface [polypeptide binding]; other site
720554006518	Walker A motif; other site
720554006519	ATP binding site [chemical binding]; other site
720554006520	hydroxycobalamin binding site [chemical binding]; other site
720554006521	Walker B motif; other site
720554006522	NAD-dependent deacetylase; Provisional; Region: PRK00481
720554006523	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
720554006524	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
720554006525	pentamer interface [polypeptide binding]; other site
720554006526	dodecaamer interface [polypeptide binding]; other site
720554006527	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
720554006528	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
720554006529	ABC transporter; Region: ABC_tran_2; pfam12848
720554006530	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
720554006531	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554006532	MULE transposase domain; Region: MULE; pfam10551
720554006533	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
720554006534	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
720554006535	active site
720554006536	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554006537	binding surface
720554006538	TPR repeat; Region: TPR_11; pfam13414
720554006539	TPR motif; other site
720554006540	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
720554006541	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554006542	metal ion-dependent adhesion site (MIDAS); other site
720554006543	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
720554006544	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
720554006545	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
720554006546	active site
720554006547	homodimer interface [polypeptide binding]; other site
720554006548	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
720554006549	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
720554006550	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
720554006551	Mg++ binding site [ion binding]; other site
720554006552	putative catalytic motif [active]
720554006553	putative substrate binding site [chemical binding]; other site
720554006554	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
720554006555	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
720554006556	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554006557	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
720554006558	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
720554006559	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
720554006560	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554006561	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
720554006562	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
720554006563	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
720554006564	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
720554006565	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
720554006566	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
720554006567	MraW methylase family; Region: Methyltransf_5; pfam01795
720554006568	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
720554006569	cell division protein MraZ; Reviewed; Region: PRK00326
720554006570	MraZ protein; Region: MraZ; pfam02381
720554006571	MraZ protein; Region: MraZ; pfam02381
720554006572	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
720554006573	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
720554006574	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
720554006575	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
720554006576	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
720554006577	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
720554006578	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
720554006579	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554006580	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554006581	metal binding site [ion binding]; metal-binding site
720554006582	active site
720554006583	I-site; other site
720554006584	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
720554006585	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
720554006586	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
720554006587	DOMON-like type 9 carbohydrate binding module of xylanases; Region: CBM9_like_1; cd00005
720554006588	Ca binding site [ion binding]; other site
720554006589	carbohydrate binding site [chemical binding]; other site
720554006590	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
720554006591	putative ligand binding site [chemical binding]; other site
720554006592	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
720554006593	DOMON-like type 9 carbohydrate binding module of xylanases; Region: CBM9_like_1; cd00005
720554006594	Ca binding site [ion binding]; other site
720554006595	carbohydrate binding site [chemical binding]; other site
720554006596	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
720554006597	Transcriptional regulators [Transcription]; Region: PurR; COG1609
720554006598	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
720554006599	DNA binding site [nucleotide binding]
720554006600	domain linker motif; other site
720554006601	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
720554006602	ligand binding site [chemical binding]; other site
720554006603	dimerization interface [polypeptide binding]; other site
720554006604	Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003
720554006605	substrate binding site [chemical binding]; other site
720554006606	active site
720554006607	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554006608	ligand binding site [chemical binding]; other site
720554006609	metal binding site [ion binding]; metal-binding site
720554006610	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006611	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006612	SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833
720554006613	active site
720554006614	catalytic triad [active]
720554006615	oxyanion hole [active]
720554006616	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006617	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
720554006618	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
720554006619	intersubunit interface [polypeptide binding]; other site
720554006620	active site
720554006621	Zn2+ binding site [ion binding]; other site
720554006622	L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-RBK_like; cd07778
720554006623	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
720554006624	putative N- and C-terminal domain interface [polypeptide binding]; other site
720554006625	putative active site [active]
720554006626	MgATP binding site [chemical binding]; other site
720554006627	catalytic site [active]
720554006628	metal binding site [ion binding]; metal-binding site
720554006629	putative carbohydrate binding site [chemical binding]; other site
720554006630	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
720554006631	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554006632	metal binding site [ion binding]; metal-binding site
720554006633	ligand binding site [chemical binding]; other site
720554006634	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006635	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
720554006636	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
720554006637	substrate binding site [chemical binding]; other site
720554006638	active site
720554006639	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554006640	metal binding site [ion binding]; metal-binding site
720554006641	ligand binding site [chemical binding]; other site
720554006642	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
720554006643	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
720554006644	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
720554006645	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
720554006646	Beta-lactamase; Region: Beta-lactamase; pfam00144
720554006647	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
720554006648	Putative esterase; Region: Esterase; pfam00756
720554006649	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554006650	metal binding site [ion binding]; metal-binding site
720554006651	ligand binding site [chemical binding]; other site
720554006652	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006653	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
720554006654	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
720554006655	active site
720554006656	Riboflavin kinase; Region: Flavokinase; pfam01687
720554006657	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
720554006658	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
720554006659	RNA binding site [nucleotide binding]; other site
720554006660	active site
720554006661	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
720554006662	DHH family; Region: DHH; pfam01368
720554006663	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
720554006664	translation initiation factor IF-2; Region: IF-2; TIGR00487
720554006665	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
720554006666	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
720554006667	G1 box; other site
720554006668	putative GEF interaction site [polypeptide binding]; other site
720554006669	GTP/Mg2+ binding site [chemical binding]; other site
720554006670	Switch I region; other site
720554006671	G2 box; other site
720554006672	G3 box; other site
720554006673	Switch II region; other site
720554006674	G4 box; other site
720554006675	G5 box; other site
720554006676	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
720554006677	Translation-initiation factor 2; Region: IF-2; pfam11987
720554006678	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
720554006679	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
720554006680	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
720554006681	putative RNA binding cleft [nucleotide binding]; other site
720554006682	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
720554006683	NusA N-terminal domain; Region: NusA_N; pfam08529
720554006684	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
720554006685	RNA binding site [nucleotide binding]; other site
720554006686	homodimer interface [polypeptide binding]; other site
720554006687	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
720554006688	G-X-X-G motif; other site
720554006689	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
720554006690	G-X-X-G motif; other site
720554006691	Sm and related proteins; Region: Sm_like; cl00259
720554006692	ribosome maturation protein RimP; Reviewed; Region: PRK00092
720554006693	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
720554006694	putative oligomer interface [polypeptide binding]; other site
720554006695	putative RNA binding site [nucleotide binding]; other site
720554006696	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
720554006697	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
720554006698	RIP metalloprotease RseP; Region: TIGR00054
720554006699	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
720554006700	active site
720554006701	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
720554006702	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
720554006703	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
720554006704	putative substrate binding region [chemical binding]; other site
720554006705	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
720554006706	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
720554006707	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
720554006708	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
720554006709	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
720554006710	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
720554006711	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
720554006712	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
720554006713	catalytic residue [active]
720554006714	putative FPP diphosphate  binding site; other site
720554006715	putative FPP binding hydrophobic cleft; other site
720554006716	dimer interface [polypeptide binding]; other site
720554006717	putative IPP diphosphate binding site; other site
720554006718	ribosome recycling factor; Reviewed; Region: frr; PRK00083
720554006719	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
720554006720	hinge region; other site
720554006721	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
720554006722	putative nucleotide binding site [chemical binding]; other site
720554006723	uridine monophosphate binding site [chemical binding]; other site
720554006724	homohexameric interface [polypeptide binding]; other site
720554006725	elongation factor Ts; Reviewed; Region: tsf; PRK12332
720554006726	UBA/TS-N domain; Region: UBA; pfam00627
720554006727	Elongation factor TS; Region: EF_TS; pfam00889
720554006728	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
720554006729	rRNA interaction site [nucleotide binding]; other site
720554006730	S8 interaction site; other site
720554006731	putative laminin-1 binding site; other site
720554006732	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
720554006733	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
720554006734	G1 box; other site
720554006735	putative GEF interaction site [polypeptide binding]; other site
720554006736	GTP/Mg2+ binding site [chemical binding]; other site
720554006737	Switch I region; other site
720554006738	G2 box; other site
720554006739	G3 box; other site
720554006740	Switch II region; other site
720554006741	G4 box; other site
720554006742	G5 box; other site
720554006743	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
720554006744	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
720554006745	YceG-like family; Region: YceG; pfam02618
720554006746	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
720554006747	dimerization interface [polypeptide binding]; other site
720554006748	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
720554006749	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554006750	S-adenosylmethionine binding site [chemical binding]; other site
720554006751	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
720554006752	Peptidase family U32; Region: Peptidase_U32; pfam01136
720554006753	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
720554006754	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
720554006755	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
720554006756	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
720554006757	RNA polymerase sigma-K factor; Region: spore_sigmaK; TIGR02846
720554006758	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554006759	Sigma-70, region 4; Region: Sigma70_r4; pfam04545
720554006760	DNA binding residues [nucleotide binding]
720554006761	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
720554006762	Domain of unknown function DUF20; Region: UPF0118; pfam01594
720554006763	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
720554006764	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
720554006765	phosphate binding site [ion binding]; other site
720554006766	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
720554006767	NADPH-dependent butanol dehydrogenase involved in the butanol and ethanol formation pathway in bacteria; Region: NADPH_BDH; cd08179
720554006768	putative active site [active]
720554006769	metal binding site [ion binding]; metal-binding site
720554006770	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cd04722
720554006771	phosphate binding site [ion binding]; other site
720554006772	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
720554006773	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
720554006774	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
720554006775	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
720554006776	substrate binding site [chemical binding]; other site
720554006777	ATP binding site [chemical binding]; other site
720554006778	Isochorismatase family; Region: Isochorismatase; pfam00857
720554006779	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
720554006780	catalytic triad [active]
720554006781	conserved cis-peptide bond; other site
720554006782	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
720554006783	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
720554006784	TM-ABC transporter signature motif; other site
720554006785	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
720554006786	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
720554006787	TM-ABC transporter signature motif; other site
720554006788	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
720554006789	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554006790	Walker A/P-loop; other site
720554006791	ATP binding site [chemical binding]; other site
720554006792	Q-loop/lid; other site
720554006793	ABC transporter signature motif; other site
720554006794	Walker B; other site
720554006795	D-loop; other site
720554006796	H-loop/switch region; other site
720554006797	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
720554006798	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
720554006799	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
720554006800	ligand binding site [chemical binding]; other site
720554006801	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
720554006802	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
720554006803	DNA-binding site [nucleotide binding]; DNA binding site
720554006804	UTRA domain; Region: UTRA; pfam07702
720554006805	flavodoxin; Provisional; Region: PRK06242
720554006806	parallel beta-helix repeat-containing protein; Region: beta_helix_1; TIGR03805
720554006807	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554006808	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554006809	MULE transposase domain; Region: MULE; pfam10551
720554006810	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554006811	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
720554006812	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554006813	Transposase domain (DUF772); Region: DUF772; pfam05598
720554006814	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554006815	putative transposase OrfB; Reviewed; Region: PHA02517
720554006816	HTH-like domain; Region: HTH_21; pfam13276
720554006817	Integrase core domain; Region: rve; pfam00665
720554006818	Integrase core domain; Region: rve_3; pfam13683
720554006819	Transposase; Region: HTH_Tnp_1; pfam01527
720554006820	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554006821	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
720554006822	Interdomain contacts; other site
720554006823	Kelch motif; Region: Kelch_1; pfam01344
720554006824	Kelch domain; Region: Kelch; smart00612
720554006825	Kelch motif; Region: Kelch_1; pfam01344
720554006826	Kelch motif; Region: Kelch_1; pfam01344
720554006827	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
720554006828	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554006829	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554006830	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554006831	RHS Repeat; Region: RHS_repeat; pfam05593
720554006832	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
720554006833	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554006834	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
720554006835	MutS domain III; Region: MutS_III; pfam05192
720554006836	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
720554006837	Walker A/P-loop; other site
720554006838	ATP binding site [chemical binding]; other site
720554006839	Q-loop/lid; other site
720554006840	ABC transporter signature motif; other site
720554006841	Walker B; other site
720554006842	D-loop; other site
720554006843	H-loop/switch region; other site
720554006844	Smr domain; Region: Smr; pfam01713
720554006845	Methyltransferase TYW3; Region: TYW3; cl00689
720554006846	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554006847	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
720554006848	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
720554006849	active site
720554006850	metal binding site [ion binding]; metal-binding site
720554006851	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
720554006852	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
720554006853	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
720554006854	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554006855	dimer interface [polypeptide binding]; other site
720554006856	conserved gate region; other site
720554006857	putative PBP binding loops; other site
720554006858	ABC-ATPase subunit interface; other site
720554006859	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
720554006860	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554006861	dimer interface [polypeptide binding]; other site
720554006862	conserved gate region; other site
720554006863	putative PBP binding loops; other site
720554006864	ABC-ATPase subunit interface; other site
720554006865	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
720554006866	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
720554006867	stage IV sporulation protein A; Region: spore_IV_A; TIGR02836
720554006868	Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547
720554006869	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
720554006870	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
720554006871	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
720554006872	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; pfam02660
720554006873	GTP-binding protein Der; Reviewed; Region: PRK00093
720554006874	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
720554006875	G1 box; other site
720554006876	GTP/Mg2+ binding site [chemical binding]; other site
720554006877	Switch I region; other site
720554006878	G2 box; other site
720554006879	Switch II region; other site
720554006880	G3 box; other site
720554006881	G4 box; other site
720554006882	G5 box; other site
720554006883	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
720554006884	G1 box; other site
720554006885	GTP/Mg2+ binding site [chemical binding]; other site
720554006886	Switch I region; other site
720554006887	G2 box; other site
720554006888	G3 box; other site
720554006889	Switch II region; other site
720554006890	G4 box; other site
720554006891	G5 box; other site
720554006892	putative FeS-containing Cyanobacterial-specific oxidoreductase; Region: cyano_FeS_chp; TIGR03279
720554006893	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
720554006894	Protein of unknown function (DUF512); Region: DUF512; pfam04459
720554006895	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
720554006896	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
720554006897	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
720554006898	propionate/acetate kinase; Provisional; Region: PRK12379
720554006899	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
720554006900	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
720554006901	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
720554006902	GatB domain; Region: GatB_Yqey; smart00845
720554006903	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
720554006904	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
720554006905	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
720554006906	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
720554006907	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
720554006908	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554006909	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554006910	DNA binding residues [nucleotide binding]
720554006911	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554006912	MULE transposase domain; Region: MULE; pfam10551
720554006913	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
720554006914	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
720554006915	nucleotide binding pocket [chemical binding]; other site
720554006916	K-X-D-G motif; other site
720554006917	catalytic site [active]
720554006918	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
720554006919	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
720554006920	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
720554006921	Dimer interface [polypeptide binding]; other site
720554006922	BRCT sequence motif; other site
720554006923	Peptidase M50B-like; Region: Peptidase_M50B; pfam13398
720554006924	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
720554006925	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
720554006926	active site
720554006927	metal binding site [ion binding]; metal-binding site
720554006928	germination protease; Provisional; Region: PRK12362
720554006929	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
720554006930	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
720554006931	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
720554006932	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
720554006933	Competence protein; Region: Competence; pfam03772
720554006934	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554006935	Bacterial SH3 domain; Region: SH3_3; pfam08239
720554006936	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
720554006937	NlpC/P60 family; Region: NLPC_P60; pfam00877
720554006938	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
720554006939	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554006940	Coenzyme A binding pocket [chemical binding]; other site
720554006941	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
720554006942	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
720554006943	thiamine biosynthesis protein ThiC; Provisional; Region: PRK13352
720554006944	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
720554006945	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
720554006946	thiamine phosphate binding site [chemical binding]; other site
720554006947	active site
720554006948	pyrophosphate binding site [ion binding]; other site
720554006949	thiamine biosynthesis protein ThiF; Provisional; Region: PRK08644
720554006950	E1_ThiF_like. Member of superfamily of activating enzymes (E1) of the ubiquitin-like proteins. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like substrate, on...; Region: E1_ThiF_like; cd01487
720554006951	putative ATP binding site [chemical binding]; other site
720554006952	putative substrate interface [chemical binding]; other site
720554006953	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
720554006954	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554006955	FeS/SAM binding site; other site
720554006956	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
720554006957	thiazole synthase; Reviewed; Region: thiG; PRK00208
720554006958	phosphate binding site [ion binding]; other site
720554006959	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
720554006960	thiS-thiF/thiG interaction site; other site
720554006961	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
720554006962	G1 box; other site
720554006963	GTP/Mg2+ binding site [chemical binding]; other site
720554006964	Switch I region; other site
720554006965	G2 box; other site
720554006966	G3 box; other site
720554006967	Switch II region; other site
720554006968	G4 box; other site
720554006969	G5 box; other site
720554006970	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
720554006971	chaperone protein DnaJ; Provisional; Region: PRK14277
720554006972	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
720554006973	S-layer homology domain; Region: SLH; pfam00395
720554006974	S-layer homology domain; Region: SLH; pfam00395
720554006975	Cadherin-like beta sandwich domain; Region: Cadherin-like; pfam12733
720554006976	Predicted membrane protein [Function unknown]; Region: COG4485
720554006977	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
720554006978	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
720554006979	Ligand binding site; other site
720554006980	Putative Catalytic site; other site
720554006981	DXD motif; other site
720554006982	Predicted membrane protein [Function unknown]; Region: COG4905
720554006983	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
720554006984	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
720554006985	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
720554006986	Protein of unknown function (DUF503); Region: DUF503; pfam04456
720554006987	Response regulator receiver domain; Region: Response_reg; pfam00072
720554006988	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554006989	active site
720554006990	phosphorylation site [posttranslational modification]
720554006991	intermolecular recognition site; other site
720554006992	dimerization interface [polypeptide binding]; other site
720554006993	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
720554006994	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
720554006995	Domain of unknown function (DUF814); Region: DUF814; pfam05670
720554006996	aspartate aminotransferase; Provisional; Region: PRK06836
720554006997	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554006998	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554006999	homodimer interface [polypeptide binding]; other site
720554007000	catalytic residue [active]
720554007001	Thiamine pyrophosphokinase; Region: TPK; cd07995
720554007002	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
720554007003	active site
720554007004	dimerization interface [polypeptide binding]; other site
720554007005	thiamine binding site [chemical binding]; other site
720554007006	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
720554007007	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
720554007008	substrate binding site [chemical binding]; other site
720554007009	hexamer interface [polypeptide binding]; other site
720554007010	metal binding site [ion binding]; metal-binding site
720554007011	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
720554007012	GTPase RsgA; Reviewed; Region: PRK00098
720554007013	RNA binding site [nucleotide binding]; other site
720554007014	homodimer interface [polypeptide binding]; other site
720554007015	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
720554007016	GTPase/Zn-binding domain interface [polypeptide binding]; other site
720554007017	GTP/Mg2+ binding site [chemical binding]; other site
720554007018	G4 box; other site
720554007019	G5 box; other site
720554007020	G1 box; other site
720554007021	Switch I region; other site
720554007022	G2 box; other site
720554007023	G3 box; other site
720554007024	Switch II region; other site
720554007025	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
720554007026	Catalytic domain of Protein Kinases; Region: PKc; cd00180
720554007027	active site
720554007028	ATP binding site [chemical binding]; other site
720554007029	substrate binding site [chemical binding]; other site
720554007030	activation loop (A-loop); other site
720554007031	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
720554007032	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
720554007033	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
720554007034	Protein phosphatase 2C; Region: PP2C; pfam00481
720554007035	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
720554007036	active site
720554007037	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14454
720554007038	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554007039	FeS/SAM binding site; other site
720554007040	16S rRNA methyltransferase B; Provisional; Region: PRK14902
720554007041	NusB family; Region: NusB; pfam01029
720554007042	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554007043	S-adenosylmethionine binding site [chemical binding]; other site
720554007044	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
720554007045	Protein of unknown function DUF116; Region: DUF116; pfam01976
720554007046	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
720554007047	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
720554007048	putative active site [active]
720554007049	substrate binding site [chemical binding]; other site
720554007050	putative cosubstrate binding site; other site
720554007051	catalytic site [active]
720554007052	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
720554007053	substrate binding site [chemical binding]; other site
720554007054	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
720554007055	active site
720554007056	catalytic residues [active]
720554007057	metal binding site [ion binding]; metal-binding site
720554007058	primosome assembly protein PriA; Validated; Region: PRK05580
720554007059	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554007060	ATP binding site [chemical binding]; other site
720554007061	putative Mg++ binding site [ion binding]; other site
720554007062	helicase superfamily c-terminal domain; Region: HELICc; smart00490
720554007063	nucleotide binding region [chemical binding]; other site
720554007064	ATP-binding site [chemical binding]; other site
720554007065	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
720554007066	N-Utilization Substance G (NusG) N terminal (NGN) insert and Lin0431 are part of DUF1312; Region: DUF1312; cd09846
720554007067	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
720554007068	ApbE family; Region: ApbE; pfam02424
720554007069	single-stranded DNA-binding protein; Provisional; Region: PRK05813
720554007070	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
720554007071	dimer interface [polypeptide binding]; other site
720554007072	ssDNA binding site [nucleotide binding]; other site
720554007073	tetramer (dimer of dimers) interface [polypeptide binding]; other site
720554007074	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554007075	Putative catalytic NodB homology domain of uncharacterized protein YlxY from Bacillus subtilis and its bacterial homologs; Region: CE4_BsYlxY_like; cd10950
720554007076	NodB motif; other site
720554007077	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
720554007078	Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair]; Region: COG2231
720554007079	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
720554007080	minor groove reading motif; other site
720554007081	helix-hairpin-helix signature motif; other site
720554007082	substrate binding pocket [chemical binding]; other site
720554007083	active site
720554007084	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
720554007085	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
720554007086	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
720554007087	active site
720554007088	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
720554007089	dimer interface [polypeptide binding]; other site
720554007090	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
720554007091	Ligand Binding Site [chemical binding]; other site
720554007092	Molecular Tunnel; other site
720554007093	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554007094	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554007095	Integrase core domain; Region: rve; pfam00665
720554007096	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554007097	metal binding site [ion binding]; metal-binding site
720554007098	ligand binding site [chemical binding]; other site
720554007099	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554007100	metal binding site [ion binding]; metal-binding site
720554007101	ligand binding site [chemical binding]; other site
720554007102	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554007103	metal binding site [ion binding]; metal-binding site
720554007104	ligand binding site [chemical binding]; other site
720554007105	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554007106	metal binding site [ion binding]; metal-binding site
720554007107	ligand binding site [chemical binding]; other site
720554007108	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA_subfamily_ECM; cd01450
720554007109	integrin inhibitor binding pocket; other site
720554007110	putative vWF-collagen binding site; other site
720554007111	glycoprotein Ib (GpIb) binding site [polypeptide binding]; other site
720554007112	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
720554007113	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
720554007114	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
720554007115	dimerization interface [polypeptide binding]; other site
720554007116	ATP binding site [chemical binding]; other site
720554007117	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
720554007118	dimerization interface [polypeptide binding]; other site
720554007119	ATP binding site [chemical binding]; other site
720554007120	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
720554007121	putative active site [active]
720554007122	catalytic triad [active]
720554007123	Transcriptional regulator [Transcription]; Region: LysR; COG0583
720554007124	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
720554007125	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
720554007126	dimerization interface [polypeptide binding]; other site
720554007127	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
720554007128	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554007129	non-specific DNA binding site [nucleotide binding]; other site
720554007130	salt bridge; other site
720554007131	sequence-specific DNA binding site [nucleotide binding]; other site
720554007132	Cupin domain; Region: Cupin_2; pfam07883
720554007133	Medium-chain acyl-CoA synthetase (MACS) of AAE_MA like; Region: MACS_AAE_MA_like; cd05970
720554007134	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
720554007135	active site
720554007136	acyl-activating enzyme (AAE) consensus motif; other site
720554007137	putative CoA binding site [chemical binding]; other site
720554007138	AMP binding site [chemical binding]; other site
720554007139	heat shock protein 90; Provisional; Region: PRK05218
720554007140	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554007141	ATP binding site [chemical binding]; other site
720554007142	Mg2+ binding site [ion binding]; other site
720554007143	G-X-G motif; other site
720554007144	ferric uptake regulator; Provisional; Region: fur; PRK09462
720554007145	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
720554007146	metal binding site 2 [ion binding]; metal-binding site
720554007147	putative DNA binding helix; other site
720554007148	metal binding site 1 [ion binding]; metal-binding site
720554007149	dimer interface [polypeptide binding]; other site
720554007150	structural Zn2+ binding site [ion binding]; other site
720554007151	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
720554007152	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
720554007153	phosphopeptide binding site; other site
720554007154	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554007155	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554007156	metal binding site [ion binding]; metal-binding site
720554007157	active site
720554007158	I-site; other site
720554007159	AAA ATPase domain; Region: AAA_16; pfam13191
720554007160	AAA ATPase domain; Region: AAA_16; pfam13191
720554007161	Predicted ATPase [General function prediction only]; Region: COG3903
720554007162	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
720554007163	G1 box; other site
720554007164	GTP/Mg2+ binding site [chemical binding]; other site
720554007165	G2 box; other site
720554007166	Switch I region; other site
720554007167	G3 box; other site
720554007168	Switch II region; other site
720554007169	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554007170	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554007171	binding surface
720554007172	TPR motif; other site
720554007173	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554007174	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007175	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007176	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007177	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
720554007178	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
720554007179	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
720554007180	active site
720554007181	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554007182	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554007183	MULE transposase domain; Region: MULE; pfam10551
720554007184	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554007185	TPR repeat; Region: TPR_11; pfam13414
720554007186	binding surface
720554007187	TPR motif; other site
720554007188	TPR repeat; Region: TPR_11; pfam13414
720554007189	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554007190	binding surface
720554007191	TPR motif; other site
720554007192	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
720554007193	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554007194	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
720554007195	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
720554007196	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554007197	ATP binding site [chemical binding]; other site
720554007198	putative Mg++ binding site [ion binding]; other site
720554007199	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
720554007200	RecX family; Region: RecX; cl00936
720554007201	Trp repressor protein; Region: Trp_repressor; cl17266
720554007202	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
720554007203	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
720554007204	active site
720554007205	NTP binding site [chemical binding]; other site
720554007206	metal binding triad [ion binding]; metal-binding site
720554007207	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
720554007208	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554007209	Zn2+ binding site [ion binding]; other site
720554007210	Mg2+ binding site [ion binding]; other site
720554007211	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
720554007212	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
720554007213	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
720554007214	Transposase; Region: HTH_Tnp_1; pfam01527
720554007215	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554007216	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554007217	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
720554007218	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
720554007219	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
720554007220	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
720554007221	CRISPR-associated protein Cas5, subtype I-B/TNEAP; Region: cas_Cas5t; TIGR01895
720554007222	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cl12040
720554007223	CRISPR-associated autoregulator DevR family; Region: cas_MJ0381; TIGR01875
720554007224	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cl00803
720554007225	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cd09754
720554007226	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cl09909
720554007227	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554007228	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554007229	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554007230	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
720554007231	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554007232	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554007233	DNA binding residues [nucleotide binding]
720554007234	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
720554007235	active site
720554007236	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
720554007237	active site
720554007238	ribulose/triose binding site [chemical binding]; other site
720554007239	phosphate binding site [ion binding]; other site
720554007240	substrate (anthranilate) binding pocket [chemical binding]; other site
720554007241	product (indole) binding pocket [chemical binding]; other site
720554007242	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
720554007243	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
720554007244	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
720554007245	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
720554007246	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
720554007247	glutamine binding [chemical binding]; other site
720554007248	catalytic triad [active]
720554007249	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
720554007250	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
720554007251	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
720554007252	helicase 45; Provisional; Region: PTZ00424
720554007253	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
720554007254	ATP binding site [chemical binding]; other site
720554007255	Mg++ binding site [ion binding]; other site
720554007256	motif III; other site
720554007257	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554007258	nucleotide binding region [chemical binding]; other site
720554007259	ATP-binding site [chemical binding]; other site
720554007260	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554007261	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554007262	Integrase core domain; Region: rve; pfam00665
720554007263	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
720554007264	GTP-binding protein YchF; Reviewed; Region: PRK09601
720554007265	YchF GTPase; Region: YchF; cd01900
720554007266	G1 box; other site
720554007267	GTP/Mg2+ binding site [chemical binding]; other site
720554007268	Switch I region; other site
720554007269	G2 box; other site
720554007270	Switch II region; other site
720554007271	G3 box; other site
720554007272	G4 box; other site
720554007273	G5 box; other site
720554007274	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
720554007275	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
720554007276	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
720554007277	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
720554007278	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554007279	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554007280	metal binding site [ion binding]; metal-binding site
720554007281	active site
720554007282	I-site; other site
720554007283	alpha-galactosidase; Provisional; Region: PRK15076
720554007284	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
720554007285	NAD binding site [chemical binding]; other site
720554007286	sugar binding site [chemical binding]; other site
720554007287	divalent metal binding site [ion binding]; other site
720554007288	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
720554007289	dimer interface [polypeptide binding]; other site
720554007290	CCC1-related family of proteins; Region: CCC1_like; cd01059
720554007291	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554007292	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554007293	metal binding site [ion binding]; metal-binding site
720554007294	active site
720554007295	I-site; other site
720554007296	EamA-like transporter family; Region: EamA; pfam00892
720554007297	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
720554007298	flagellar operon protein TIGR03826; Region: YvyF
720554007299	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
720554007300	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
720554007301	N-acetyl-D-glucosamine binding site [chemical binding]; other site
720554007302	catalytic residue [active]
720554007303	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
720554007304	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
720554007305	CoA-binding site [chemical binding]; other site
720554007306	ATP-binding [chemical binding]; other site
720554007307	DNA polymerase I; Provisional; Region: PRK05755
720554007308	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
720554007309	active site
720554007310	metal binding site 1 [ion binding]; metal-binding site
720554007311	putative 5' ssDNA interaction site; other site
720554007312	metal binding site 3; metal-binding site
720554007313	metal binding site 2 [ion binding]; metal-binding site
720554007314	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
720554007315	putative DNA binding site [nucleotide binding]; other site
720554007316	putative metal binding site [ion binding]; other site
720554007317	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
720554007318	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
720554007319	active site
720554007320	DNA binding site [nucleotide binding]
720554007321	catalytic site [active]
720554007322	Protein of unknown function (DUF3006); Region: DUF3006; pfam11213
720554007323	Putative zinc-finger; Region: zf-HC2; pfam13490
720554007324	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554007325	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554007326	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554007327	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
720554007328	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554007329	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554007330	DNA binding residues [nucleotide binding]
720554007331	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
720554007332	putative active site [active]
720554007333	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
720554007334	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
720554007335	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554007336	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
720554007337	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
720554007338	Walker A/P-loop; other site
720554007339	ATP binding site [chemical binding]; other site
720554007340	Q-loop/lid; other site
720554007341	TATA element modulatory factor 1 TATA binding; Region: TMF_TATA_bd; pfam12325
720554007342	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
720554007343	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
720554007344	ABC transporter signature motif; other site
720554007345	Walker B; other site
720554007346	D-loop; other site
720554007347	H-loop/switch region; other site
720554007348	Pyridoxal phosphate biosynthesis protein [Coenzyme metabolism]; Region: PdxA; COG1995
720554007349	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
720554007350	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
720554007351	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
720554007352	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
720554007353	HlyD family secretion protein; Region: HlyD_3; pfam13437
720554007354	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554007355	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554007356	Walker A/P-loop; other site
720554007357	ATP binding site [chemical binding]; other site
720554007358	Q-loop/lid; other site
720554007359	ABC transporter signature motif; other site
720554007360	Walker B; other site
720554007361	D-loop; other site
720554007362	H-loop/switch region; other site
720554007363	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
720554007364	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
720554007365	FtsX-like permease family; Region: FtsX; pfam02687
720554007366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
720554007367	H+ Antiporter protein; Region: 2A0121; TIGR00900
720554007368	putative substrate translocation pore; other site
720554007369	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
720554007370	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
720554007371	active site
720554007372	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007373	thioester reductase domain; Region: Thioester-redct; TIGR01746
720554007374	extended (e) SDRs, subgroup 1; Region: SDR_e1; cd05235
720554007375	putative NAD(P) binding site [chemical binding]; other site
720554007376	active site
720554007377	putative substrate binding site [chemical binding]; other site
720554007378	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
720554007379	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
720554007380	acyl-activating enzyme (AAE) consensus motif; other site
720554007381	AMP binding site [chemical binding]; other site
720554007382	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007383	Condensation domain; Region: Condensation; pfam00668
720554007384	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
720554007385	Condensation domain; Region: Condensation; pfam00668
720554007386	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
720554007387	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
720554007388	acyl-activating enzyme (AAE) consensus motif; other site
720554007389	AMP binding site [chemical binding]; other site
720554007390	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007391	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
720554007392	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
720554007393	active site
720554007394	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
720554007395	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
720554007396	putative NADP binding site [chemical binding]; other site
720554007397	active site
720554007398	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007399	Condensation domain; Region: Condensation; pfam00668
720554007400	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
720554007401	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
720554007402	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
720554007403	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
720554007404	active site
720554007405	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
720554007406	putative NADP binding site [chemical binding]; other site
720554007407	KR domain; Region: KR; pfam08659
720554007408	active site
720554007409	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007410	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
720554007411	Peptidase family M28; Region: Peptidase_M28; pfam04389
720554007412	metal binding site [ion binding]; metal-binding site
720554007413	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
720554007414	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
720554007415	active site
720554007416	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
720554007417	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
720554007418	putative NADP binding site [chemical binding]; other site
720554007419	active site
720554007420	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007421	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
720554007422	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
720554007423	active site
720554007424	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
720554007425	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
720554007426	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
720554007427	putative NADP binding site [chemical binding]; other site
720554007428	active site
720554007429	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007430	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
720554007431	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
720554007432	acyl-CoA synthetase; Validated; Region: PRK09192
720554007433	The adenylation domain of nonribosomal peptide synthetases (NRPS) similar to mycosubtilin synthase subunit A (MycA); Region: A_NRPS_MycA_like; cd05908
720554007434	acyl-activating enzyme (AAE) consensus motif; other site
720554007435	putative AMP binding site [chemical binding]; other site
720554007436	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
720554007437	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
720554007438	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
720554007439	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554007440	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
720554007441	Integrase core domain; Region: rve; pfam00665
720554007442	Integrase core domain; Region: rve_3; pfam13683
720554007443	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
720554007444	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
720554007445	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554007446	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554007447	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554007448	Transposase; Region: HTH_Tnp_1; cl17663
720554007449	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554007450	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554007451	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554007452	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554007453	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554007454	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554007455	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554007456	Transposase; Region: HTH_Tnp_1; cl17663
720554007457	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
720554007458	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554007459	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554007460	protein-splicing catalytic site; other site
720554007461	thioester formation/cholesterol transfer; other site
720554007462	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554007463	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH; Region: AHH; pfam14412
720554007464	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
720554007465	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554007466	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554007467	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554007468	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554007469	Transposase; Region: HTH_Tnp_1; cl17663
720554007470	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554007471	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554007472	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554007473	RHS Repeat; Region: RHS_repeat; pfam05593
720554007474	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554007475	RHS Repeat; Region: RHS_repeat; pfam05593
720554007476	RHS Repeat; Region: RHS_repeat; pfam05593
720554007477	RHS Repeat; Region: RHS_repeat; pfam05593
720554007478	RHS Repeat; Region: RHS_repeat; pfam05593
720554007479	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554007480	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
720554007481	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554007482	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
720554007483	protein-splicing catalytic site; other site
720554007484	thioester formation/cholesterol transfer; other site
720554007485	Pretoxin HINT domain; Region: PT-HINT; pfam07591
720554007486	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554007487	MULE transposase domain; Region: MULE; pfam10551
720554007488	RHS Repeat; Region: RHS_repeat; pfam05593
720554007489	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
720554007490	Putative Ig domain; Region: He_PIG; pfam05345
720554007491	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554007492	Protein of unknown function (DUF2947); Region: DUF2947; pfam11163
720554007493	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
720554007494	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554007495	ABC-ATPase subunit interface; other site
720554007496	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
720554007497	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
720554007498	Walker A/P-loop; other site
720554007499	ATP binding site [chemical binding]; other site
720554007500	Q-loop/lid; other site
720554007501	ABC transporter signature motif; other site
720554007502	Walker B; other site
720554007503	D-loop; other site
720554007504	H-loop/switch region; other site
720554007505	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
720554007506	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554007507	substrate binding pocket [chemical binding]; other site
720554007508	membrane-bound complex binding site; other site
720554007509	hinge residues; other site
720554007510	Protein of unknown function (DUF1847); Region: DUF1847; pfam08901
720554007511	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
720554007512	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
720554007513	methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370
720554007514	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
720554007515	B12 binding site [chemical binding]; other site
720554007516	cobalt ligand [ion binding]; other site
720554007517	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554007518	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554007519	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
720554007520	dimer interface [polypeptide binding]; other site
720554007521	ADP-ribose binding site [chemical binding]; other site
720554007522	active site
720554007523	nudix motif; other site
720554007524	metal binding site [ion binding]; metal-binding site
720554007525	Uncharacterized small protein (DUF2292); Region: DUF2292; pfam10055
720554007526	2-ketoisovalerate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11864
720554007527	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
720554007528	TPP-binding site [chemical binding]; other site
720554007529	pyruvate ferredoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK08367
720554007530	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
720554007531	dimer interface [polypeptide binding]; other site
720554007532	PYR/PP interface [polypeptide binding]; other site
720554007533	TPP binding site [chemical binding]; other site
720554007534	substrate binding site [chemical binding]; other site
720554007535	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
720554007536	Ferredoxin [Energy production and conversion]; Region: COG1146
720554007537	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
720554007538	2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; Region: PorC_KorC; TIGR02175
720554007539	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
720554007540	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
720554007541	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
720554007542	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554007543	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554007544	homodimer interface [polypeptide binding]; other site
720554007545	catalytic residue [active]
720554007546	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
720554007547	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
720554007548	acyl-activating enzyme (AAE) consensus motif; other site
720554007549	AMP binding site [chemical binding]; other site
720554007550	active site
720554007551	CoA binding site [chemical binding]; other site
720554007552	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554007553	dimer interface [polypeptide binding]; other site
720554007554	conserved gate region; other site
720554007555	putative PBP binding loops; other site
720554007556	ABC-ATPase subunit interface; other site
720554007557	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
720554007558	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
720554007559	Walker A/P-loop; other site
720554007560	ATP binding site [chemical binding]; other site
720554007561	Q-loop/lid; other site
720554007562	ABC transporter signature motif; other site
720554007563	Walker B; other site
720554007564	D-loop; other site
720554007565	H-loop/switch region; other site
720554007566	NIL domain; Region: NIL; pfam09383
720554007567	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
720554007568	Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894
720554007569	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
720554007570	catalytic loop [active]
720554007571	iron binding site [ion binding]; other site
720554007572	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
720554007573	nucleotide binding site [chemical binding]; other site
720554007574	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
720554007575	MtaA_CmuA_like family. MtaA/CmuA, also MtsA, or methyltransferase 2 (MT2) MT2-A and MT2-M isozymes, are methylcobamide:Coenzyme M methyltransferases, which play a role in metabolic pathways of methane formation from various substrates, such as methylated...; Region: Mta_CmuA_like; cd03307
720554007576	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
720554007577	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554007578	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554007579	homodimer interface [polypeptide binding]; other site
720554007580	catalytic residue [active]
720554007581	ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606
720554007582	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_I; cd01990
720554007583	Ligand Binding Site [chemical binding]; other site
720554007584	Predicted transcriptional regulator [Transcription]; Region: COG1959
720554007585	Transcriptional regulator; Region: Rrf2; cl17282
720554007586	tRNAHis guanylyltransferase; Region: Thg1; pfam04446
720554007587	Uncharacterized conserved protein [Function unknown]; Region: COG4021
720554007588	Thg1 C terminal domain; Region: Thg1C; pfam14413
720554007589	AAA domain; Region: AAA_33; pfam13671
720554007590	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
720554007591	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
720554007592	DNA binding residues [nucleotide binding]
720554007593	dimer interface [polypeptide binding]; other site
720554007594	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
720554007595	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
720554007596	putative active site pocket [active]
720554007597	dimerization interface [polypeptide binding]; other site
720554007598	putative catalytic residue [active]
720554007599	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554007600	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554007601	Integrase core domain; Region: rve; pfam00665
720554007602	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554007603	MULE transposase domain; Region: MULE; pfam10551
720554007604	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554007605	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554007606	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554007607	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554007608	dockerin binding interface; other site
720554007609	S-layer homology domain; Region: SLH; pfam00395
720554007610	S-layer homology domain; Region: SLH; pfam00395
720554007611	S-layer homology domain; Region: SLH; pfam00395
720554007612	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
720554007613	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
720554007614	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554007615	metal binding site [ion binding]; metal-binding site
720554007616	ligand binding site [chemical binding]; other site
720554007617	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554007618	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554007619	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
720554007620	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
720554007621	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554007622	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007623	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007624	D-alanine--D-alanine ligase; Region: D_ala_D_alaTIGR; TIGR01205
720554007625	ATP-grasp domain; Region: ATP-grasp_4; cl17255
720554007626	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
720554007627	Domain of unknown function (DUF4363); Region: DUF4363; pfam14276
720554007628	Predicted membrane protein [Function unknown]; Region: COG2323
720554007629	pyruvate phosphate dikinase; Provisional; Region: PRK09279
720554007630	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
720554007631	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
720554007632	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
720554007633	glycyl-tRNA synthetase; Provisional; Region: PRK04173
720554007634	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
720554007635	motif 1; other site
720554007636	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
720554007637	active site
720554007638	motif 2; other site
720554007639	motif 3; other site
720554007640	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
720554007641	anticodon binding site; other site
720554007642	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
720554007643	Flavoprotein; Region: Flavoprotein; pfam02441
720554007644	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
720554007645	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
720554007646	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
720554007647	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
720554007648	catalytic site [active]
720554007649	G-X2-G-X-G-K; other site
720554007650	hypothetical protein; Provisional; Region: PRK04323
720554007651	hypothetical protein; Provisional; Region: PRK11820
720554007652	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
720554007653	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
720554007654	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
720554007655	active site
720554007656	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
720554007657	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
720554007658	putative sugar binding sites [chemical binding]; other site
720554007659	Q-X-W motif; other site
720554007660	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554007661	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554007662	Response regulator receiver domain; Region: Response_reg; pfam00072
720554007663	active site
720554007664	phosphorylation site [posttranslational modification]
720554007665	intermolecular recognition site; other site
720554007666	dimerization interface [polypeptide binding]; other site
720554007667	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
720554007668	RNA methyltransferase, RsmE family; Region: TIGR00046
720554007669	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
720554007670	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554007671	S-adenosylmethionine binding site [chemical binding]; other site
720554007672	chaperone protein DnaJ; Provisional; Region: PRK14277
720554007673	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
720554007674	HSP70 interaction site [polypeptide binding]; other site
720554007675	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
720554007676	substrate binding site [polypeptide binding]; other site
720554007677	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
720554007678	Zn binding sites [ion binding]; other site
720554007679	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
720554007680	dimer interface [polypeptide binding]; other site
720554007681	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
720554007682	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
720554007683	nucleotide binding site [chemical binding]; other site
720554007684	NEF interaction site [polypeptide binding]; other site
720554007685	SBD interface [polypeptide binding]; other site
720554007686	GrpE; Region: GrpE; pfam01025
720554007687	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
720554007688	dimer interface [polypeptide binding]; other site
720554007689	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
720554007690	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
720554007691	coproporphyrinogen III oxidase; Provisional; Region: PRK05799
720554007692	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554007693	FeS/SAM binding site; other site
720554007694	HemN C-terminal domain; Region: HemN_C; pfam06969
720554007695	GTP-binding protein LepA; Provisional; Region: PRK05433
720554007696	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
720554007697	G1 box; other site
720554007698	putative GEF interaction site [polypeptide binding]; other site
720554007699	GTP/Mg2+ binding site [chemical binding]; other site
720554007700	Switch I region; other site
720554007701	G2 box; other site
720554007702	G3 box; other site
720554007703	Switch II region; other site
720554007704	G4 box; other site
720554007705	G5 box; other site
720554007706	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
720554007707	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
720554007708	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
720554007709	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
720554007710	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
720554007711	active site
720554007712	catalytic site [active]
720554007713	Stage II sporulation protein P (SpoIIP); Region: SpoIIP; pfam07454
720554007714	stage II sporulation protein P; Region: spore_II_P; TIGR02867
720554007715	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
720554007716	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
720554007717	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
720554007718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
720554007719	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
720554007720	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
720554007721	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
720554007722	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
720554007723	Catalytic site [active]
720554007724	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
720554007725	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
720554007726	dimer interface [polypeptide binding]; other site
720554007727	anticodon binding site; other site
720554007728	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
720554007729	homodimer interface [polypeptide binding]; other site
720554007730	motif 1; other site
720554007731	active site
720554007732	motif 2; other site
720554007733	GAD domain; Region: GAD; pfam02938
720554007734	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
720554007735	motif 3; other site
720554007736	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
720554007737	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
720554007738	dimer interface [polypeptide binding]; other site
720554007739	motif 1; other site
720554007740	active site
720554007741	motif 2; other site
720554007742	motif 3; other site
720554007743	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
720554007744	anticodon binding site; other site
720554007745	coproporphyrinogen III oxidase; Provisional; Region: PRK08207
720554007746	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554007747	FeS/SAM binding site; other site
720554007748	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
720554007749	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
720554007750	putative active site [active]
720554007751	dimerization interface [polypeptide binding]; other site
720554007752	putative tRNAtyr binding site [nucleotide binding]; other site
720554007753	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
720554007754	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554007755	Zn2+ binding site [ion binding]; other site
720554007756	Mg2+ binding site [ion binding]; other site
720554007757	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
720554007758	synthetase active site [active]
720554007759	NTP binding site [chemical binding]; other site
720554007760	metal binding site [ion binding]; metal-binding site
720554007761	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
720554007762	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
720554007763	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554007764	active site
720554007765	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
720554007766	DHH family; Region: DHH; pfam01368
720554007767	DHHA1 domain; Region: DHHA1; pfam02272
720554007768	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
720554007769	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554007770	Yqey-like protein; Region: YqeY; pfam09424
720554007771	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
720554007772	SWIM zinc finger; Region: SWIM; pfam04434
720554007773	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
720554007774	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
720554007775	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554007776	ATP binding site [chemical binding]; other site
720554007777	putative Mg++ binding site [ion binding]; other site
720554007778	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554007779	nucleotide binding region [chemical binding]; other site
720554007780	ATP-binding site [chemical binding]; other site
720554007781	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
720554007782	Bacterial sugar transferase; Region: Bac_transf; pfam02397
720554007783	Predicted integral membrane protein [Function unknown]; Region: COG5652
720554007784	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007785	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554007786	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554007787	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554007788	seryl-tRNA synthetase; Provisional; Region: PRK05431
720554007789	HEAT repeats; Region: HEAT_2; pfam13646
720554007790	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
720554007791	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
720554007792	O-Antigen ligase; Region: Wzy_C; pfam04932
720554007793	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
720554007794	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554007795	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554007796	This family is most closely related to the GT1 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1); Region: GT1_CapH_like; cd03812
720554007797	putative ADP-binding pocket [chemical binding]; other site
720554007798	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
720554007799	active site
720554007800	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554007801	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
720554007802	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
720554007803	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
720554007804	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
720554007805	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
720554007806	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
720554007807	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
720554007808	CotH protein; Region: CotH; pfam08757
720554007809	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554007810	Lamin Tail Domain; Region: LTD; pfam00932
720554007811	Fn3 associated; Region: Fn3_assoc; pfam13287
720554007812	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
720554007813	Bacterial sugar transferase; Region: Bac_transf; pfam02397
720554007814	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554007815	MULE transposase domain; Region: MULE; pfam10551
720554007816	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
720554007817	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
720554007818	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
720554007819	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
720554007820	active site
720554007821	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
720554007822	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
720554007823	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554007824	putative ADP-binding pocket [chemical binding]; other site
720554007825	Transcription antiterminator [Transcription]; Region: NusG; COG0250
720554007826	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cd08000
720554007827	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
720554007828	heterodimer interface [polypeptide binding]; other site
720554007829	homodimer interface [polypeptide binding]; other site
720554007830	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
720554007831	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
720554007832	substrate binding site; other site
720554007833	tetramer interface; other site
720554007834	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
720554007835	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
720554007836	NADP binding site [chemical binding]; other site
720554007837	active site
720554007838	putative substrate binding site [chemical binding]; other site
720554007839	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
720554007840	Chain length determinant protein; Region: Wzz; cl15801
720554007841	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
720554007842	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
720554007843	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554007844	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
720554007845	S-layer homology domain; Region: SLH; pfam00395
720554007846	S-layer homology domain; Region: SLH; pfam00395
720554007847	S-layer homology domain; Region: SLH; pfam00395
720554007848	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
720554007849	nucleotide binding site/active site [active]
720554007850	HIT family signature motif; other site
720554007851	catalytic residue [active]
720554007852	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
720554007853	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
720554007854	motif 1; other site
720554007855	active site
720554007856	motif 2; other site
720554007857	motif 3; other site
720554007858	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
720554007859	Domain of unknown function DUF20; Region: UPF0118; pfam01594
720554007860	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
720554007861	PRC-barrel domain containing protein [General function prediction only]; Region: COG3881
720554007862	PRC-barrel domain; Region: PRC; pfam05239
720554007863	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
720554007864	Uncharacterized conserved protein [Function unknown]; Region: COG4198
720554007865	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554007866	Cellulose binding domain; Region: CBM_3; cl03026
720554007867	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554007868	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554007869	TPR motif; other site
720554007870	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554007871	binding surface
720554007872	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554007873	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554007874	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554007875	binding surface
720554007876	TPR motif; other site
720554007877	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554007878	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
720554007879	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554007880	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554007881	DNA translocase FtsK; Provisional; Region: PRK10263
720554007882	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
720554007883	Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009
720554007884	Zn binding site [ion binding]; other site
720554007885	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554007886	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554007887	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554007888	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
720554007889	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
720554007890	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
720554007891	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
720554007892	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
720554007893	ATP binding site [chemical binding]; other site
720554007894	Walker A motif; other site
720554007895	hexamer interface [polypeptide binding]; other site
720554007896	Walker B motif; other site
720554007897	AAA domain; Region: AAA_31; pfam13614
720554007898	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554007899	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554007900	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
720554007901	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554007902	ATP binding site [chemical binding]; other site
720554007903	Mg2+ binding site [ion binding]; other site
720554007904	G-X-G motif; other site
720554007905	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
720554007906	Radical SAM superfamily; Region: Radical_SAM; pfam04055
720554007907	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554007908	FeS/SAM binding site; other site
720554007909	Protein of unknown function (DUF4080); Region: DUF4080; pfam13311
720554007910	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
720554007911	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
720554007912	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
720554007913	Protein of unknown function (DUF342); Region: DUF342; pfam03961
720554007914	monogalactosyldiacylglycerol synthase; Region: PLN02605
720554007915	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
720554007916	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
720554007917	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
720554007918	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
720554007919	TrkA-N domain; Region: TrkA_N; pfam02254
720554007920	TrkA-C domain; Region: TrkA_C; pfam02080
720554007921	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
720554007922	TrkA-N domain; Region: TrkA_N; pfam02254
720554007923	Predicted membrane protein [Function unknown]; Region: COG2323
720554007924	Domain of unknown function (DUF4363); Region: DUF4363; pfam14276
720554007925	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
720554007926	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
720554007927	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
720554007928	putative lipid kinase; Reviewed; Region: PRK13059
720554007929	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
720554007930	ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: GlgC; COG0448
720554007931	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
720554007932	ligand binding site; other site
720554007933	oligomer interface; other site
720554007934	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
720554007935	dimer interface [polypeptide binding]; other site
720554007936	N-terminal domain interface [polypeptide binding]; other site
720554007937	sulfate 1 binding site; other site
720554007938	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
720554007939	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
720554007940	ligand binding site; other site
720554007941	oligomer interface; other site
720554007942	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
720554007943	dimer interface [polypeptide binding]; other site
720554007944	N-terminal domain interface [polypeptide binding]; other site
720554007945	sulfate 1 binding site; other site
720554007946	Response regulator receiver domain; Region: Response_reg; pfam00072
720554007947	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554007948	active site
720554007949	phosphorylation site [posttranslational modification]
720554007950	intermolecular recognition site; other site
720554007951	dimerization interface [polypeptide binding]; other site
720554007952	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554007953	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554007954	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554007955	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
720554007956	catalytic residues [active]
720554007957	Carbohydrate binding domain; Region: CBM_25; smart01066
720554007958	Methyltransferase domain; Region: Methyltransf_31; pfam13847
720554007959	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554007960	S-adenosylmethionine binding site [chemical binding]; other site
720554007961	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554007962	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
720554007963	RNA binding surface [nucleotide binding]; other site
720554007964	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
720554007965	active site
720554007966	uracil binding [chemical binding]; other site
720554007967	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
720554007968	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554007969	S-adenosylmethionine binding site [chemical binding]; other site
720554007970	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
720554007971	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554007972	dimer interface [polypeptide binding]; other site
720554007973	putative CheW interface [polypeptide binding]; other site
720554007974	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
720554007975	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
720554007976	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
720554007977	catalytic core [active]
720554007978	cobalamin synthase; Reviewed; Region: cobS; PRK00235
720554007979	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554007980	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
720554007981	homotrimer interface [polypeptide binding]; other site
720554007982	Walker A motif; other site
720554007983	GTP binding site [chemical binding]; other site
720554007984	Walker B motif; other site
720554007985	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
720554007986	aspartate kinase; Reviewed; Region: PRK09034
720554007987	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
720554007988	nucleotide binding site [chemical binding]; other site
720554007989	substrate binding site [chemical binding]; other site
720554007990	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
720554007991	allosteric regulatory residue; other site
720554007992	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
720554007993	homoserine dehydrogenase; Provisional; Region: PRK06349
720554007994	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
720554007995	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
720554007996	hypothetical protein; Provisional; Region: PRK04435
720554007997	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
720554007998	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554007999	active site
720554008000	phosphorylation site [posttranslational modification]
720554008001	intermolecular recognition site; other site
720554008002	dimerization interface [polypeptide binding]; other site
720554008003	Domain of unknown function (DUF3369); Region: DUF3369; pfam11849
720554008004	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554008005	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554008006	Zn2+ binding site [ion binding]; other site
720554008007	Mg2+ binding site [ion binding]; other site
720554008008	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
720554008009	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
720554008010	Response regulator receiver domain; Region: Response_reg; pfam00072
720554008011	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554008012	active site
720554008013	phosphorylation site [posttranslational modification]
720554008014	intermolecular recognition site; other site
720554008015	dimerization interface [polypeptide binding]; other site
720554008016	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
720554008017	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
720554008018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554008019	catalytic residue [active]
720554008020	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
720554008021	nucleophile elbow; other site
720554008022	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
720554008023	active site
720554008024	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
720554008025	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
720554008026	Double zinc ribbon; Region: DZR; pfam12773
720554008027	DNA directed RNA polymerase, 7 kDa subunit; Region: DNA_RNApol_7kD; cl00874
720554008028	Repair protein; Region: Repair_PSII; pfam04536
720554008029	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
720554008030	Acyltransferase family; Region: Acyl_transf_3; pfam01757
720554008031	YhhN-like protein; Region: YhhN; cl01505
720554008032	3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Region: LeuD; COG0066
720554008033	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
720554008034	substrate binding site [chemical binding]; other site
720554008035	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
720554008036	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
720554008037	substrate binding site [chemical binding]; other site
720554008038	ligand binding site [chemical binding]; other site
720554008039	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
720554008040	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
720554008041	HSP70 interaction site [polypeptide binding]; other site
720554008042	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008043	binding surface
720554008044	TPR repeat; Region: TPR_11; pfam13414
720554008045	TPR motif; other site
720554008046	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
720554008047	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
720554008048	nucleotide binding site [chemical binding]; other site
720554008049	putative NEF/HSP70 interaction site [polypeptide binding]; other site
720554008050	SBD interface [polypeptide binding]; other site
720554008051	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
720554008052	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
720554008053	putative FMN binding site [chemical binding]; other site
720554008054	NAD(P)H:flavin oxidoreductase-like family 2.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_2; cd02151
720554008055	putative FMN binding site [chemical binding]; other site
720554008056	VanZ like family; Region: VanZ; pfam04892
720554008057	manganese transport transcriptional regulator; Provisional; Region: PRK03902
720554008058	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
720554008059	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
720554008060	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
720554008061	Rubrerythrin [Energy production and conversion]; Region: COG1592
720554008062	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
720554008063	binuclear metal center [ion binding]; other site
720554008064	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
720554008065	iron binding site [ion binding]; other site
720554008066	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
720554008067	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
720554008068	active site
720554008069	trimer interface [polypeptide binding]; other site
720554008070	allosteric site; other site
720554008071	active site lid [active]
720554008072	hexamer (dimer of trimers) interface [polypeptide binding]; other site
720554008073	Putative glucose-1-phosphate thymidylyltransferase, C-terminal Left-handed parallel beta-Helix (LbH) domain: Proteins in this family show simlarity to glucose-1-phosphate adenylyltransferases in that they contain N-terminal catalytic domains that...; Region: LbH_G1P_TT_C_like; cd05636
720554008074	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
720554008075	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246
720554008076	putative dimer interface [polypeptide binding]; other site
720554008077	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554008078	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
720554008079	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
720554008080	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
720554008081	Domain of unknown function (DUF1848); Region: DUF1848; pfam08902
720554008082	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
720554008083	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
720554008084	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
720554008085	TIGR02687 family protein; Region: TIGR02687
720554008086	PglZ domain; Region: PglZ; pfam08665
720554008087	Divergent AAA domain; Region: AAA_4; pfam04326
720554008088	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
720554008089	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554008090	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
720554008091	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
720554008092	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
720554008093	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
720554008094	active site
720554008095	LysE type translocator; Region: LysE; pfam01810
720554008096	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
720554008097	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
720554008098	dimer interface [polypeptide binding]; other site
720554008099	active site
720554008100	glycine-pyridoxal phosphate binding site [chemical binding]; other site
720554008101	folate binding site [chemical binding]; other site
720554008102	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
720554008103	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
720554008104	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
720554008105	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554008106	S-layer homology domain; Region: SLH; pfam00395
720554008107	S-layer homology domain; Region: SLH; pfam00395
720554008108	S-layer homology domain; Region: SLH; pfam00395
720554008109	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
720554008110	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554008111	metal ion-dependent adhesion site (MIDAS); other site
720554008112	S-layer homology domain; Region: SLH; pfam00395
720554008113	S-layer homology domain; Region: SLH; pfam00395
720554008114	TniQ; Region: TniQ; pfam06527
720554008115	potential frameshift: common BLAST hit: gi|125973631|ref|YP_001037541.1| HMG-I and HMG-Y, DNA-binding
720554008116	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
720554008117	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
720554008118	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
720554008119	transposase; Provisional; Region: PRK06526
720554008120	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008121	Walker A motif; other site
720554008122	ATP binding site [chemical binding]; other site
720554008123	Walker B motif; other site
720554008124	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554008125	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554008126	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554008127	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554008128	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554008129	MULE transposase domain; Region: MULE; pfam10551
720554008130	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554008131	MULE transposase domain; Region: MULE; pfam10551
720554008132	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
720554008133	Mg binding site [ion binding]; other site
720554008134	nucleotide binding site [chemical binding]; other site
720554008135	putative protofilament interface [polypeptide binding]; other site
720554008136	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554008137	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554008138	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554008139	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554008140	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
720554008141	four helix bundle protein; Region: TIGR02436
720554008142	Domain of unknown function (DUF2703); Region: DUF2703; pfam10865
720554008143	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
720554008144	Predicted permeases [General function prediction only]; Region: COG0701
720554008145	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
720554008146	Low molecular weight phosphatase family; Region: LMWPc; cd00115
720554008147	active site
720554008148	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
720554008149	arsenical-resistance protein; Region: acr3; TIGR00832
720554008150	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554008151	dimerization interface [polypeptide binding]; other site
720554008152	putative DNA binding site [nucleotide binding]; other site
720554008153	putative Zn2+ binding site [ion binding]; other site
720554008154	Polyferredoxin [Energy production and conversion]; Region: NapH; COG0348
720554008155	Uncharacterized conserved protein [Function unknown]; Region: COG3339
720554008156	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
720554008157	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
720554008158	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
720554008159	glutaminase active site [active]
720554008160	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
720554008161	dimer interface [polypeptide binding]; other site
720554008162	active site
720554008163	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
720554008164	dimer interface [polypeptide binding]; other site
720554008165	active site
720554008166	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
720554008167	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
720554008168	active site
720554008169	substrate binding site [chemical binding]; other site
720554008170	metal binding site [ion binding]; metal-binding site
720554008171	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
720554008172	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
720554008173	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
720554008174	YbbR-like protein; Region: YbbR; pfam07949
720554008175	Uncharacterized conserved protein [Function unknown]; Region: COG1624
720554008176	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
720554008177	Pyruvate-formate lyase-activating enzyme [Posttranslational modification, protein turnover, chaperones]; Region: PflA; COG1180
720554008178	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554008179	FeS/SAM binding site; other site
720554008180	hypothetical protein; Provisional; Region: PRK03881
720554008181	The N-terminal domain, an extradiol dioxygenase class III subunit B-like domain, of unknown proteins containing a C-terminal AMMECR1 domain; Region: ED_3B_N_AMMECR1; cd07951
720554008182	AMMECR1; Region: AMMECR1; pfam01871
720554008183	GEMM cis-regulatory element
720554008184	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
720554008185	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
720554008186	G1 box; other site
720554008187	GTP/Mg2+ binding site [chemical binding]; other site
720554008188	Switch I region; other site
720554008189	G2 box; other site
720554008190	G3 box; other site
720554008191	Switch II region; other site
720554008192	G4 box; other site
720554008193	G5 box; other site
720554008194	Nucleoside recognition; Region: Gate; pfam07670
720554008195	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
720554008196	Nucleoside recognition; Region: Gate; pfam07670
720554008197	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
720554008198	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
720554008199	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
720554008200	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
720554008201	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
720554008202	Protein of unknown function (DUF970); Region: DUF970; cl17525
720554008203	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
720554008204	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
720554008205	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
720554008206	PilZ domain; Region: PilZ; pfam07238
720554008207	Uncharacterized ACR, YagE family COG1723; Region: DUF155; pfam02582
720554008208	Uncharacterized ACR, YagE family COG1723; Region: DUF155; pfam02582
720554008209	Small acid-soluble spore protein H family; Region: SspH; cl06949
720554008210	Family description; Region: VCBS; pfam13517
720554008211	endoglucanase; Region: PLN02420
720554008212	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554008213	Cellulose binding domain; Region: CBM_3; pfam00942
720554008214	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008215	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008216	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
720554008217	Glucuronate isomerase; Region: UxaC; pfam02614
720554008218	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
720554008219	S-layer homology domain; Region: SLH; pfam00395
720554008220	S-layer homology domain; Region: SLH; pfam00395
720554008221	S-layer homology domain; Region: SLH; pfam00395
720554008222	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
720554008223	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
720554008224	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
720554008225	active site
720554008226	putative substrate binding pocket [chemical binding]; other site
720554008227	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
720554008228	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
720554008229	homotetramer interface [polypeptide binding]; other site
720554008230	ligand binding site [chemical binding]; other site
720554008231	catalytic site [active]
720554008232	NAD binding site [chemical binding]; other site
720554008233	purine nucleoside phosphorylase; Provisional; Region: PRK08202
720554008234	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554008235	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554008236	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554008237	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554008238	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
720554008239	SpoVR like protein; Region: SpoVR; pfam04293
720554008240	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554008241	metal ion-dependent adhesion site (MIDAS); other site
720554008242	Putative Ser protein kinase [Signal transduction mechanisms]; Region: PrkA; COG2766
720554008243	AAA ATPase domain; Region: AAA_16; pfam13191
720554008244	AAA domain; Region: AAA_17; pfam13207
720554008245	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
720554008246	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
720554008247	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
720554008248	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
720554008249	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
720554008250	Clp amino terminal domain; Region: Clp_N; pfam02861
720554008251	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008252	Walker A motif; other site
720554008253	ATP binding site [chemical binding]; other site
720554008254	Walker B motif; other site
720554008255	arginine finger; other site
720554008256	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008257	Walker A motif; other site
720554008258	ATP binding site [chemical binding]; other site
720554008259	Walker B motif; other site
720554008260	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
720554008261	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
720554008262	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
720554008263	Protein of unknown function (DUF3131); Region: DUF3131; pfam11329
720554008264	Putative glucoamylase; Region: Glycoamylase; pfam10091
720554008265	Second GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_2_like; cd11753
720554008266	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
720554008267	First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756
720554008268	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
720554008269	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
720554008270	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008271	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008272	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
720554008273	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
720554008274	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
720554008275	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
720554008276	23S rRNA binding site [nucleotide binding]; other site
720554008277	L21 binding site [polypeptide binding]; other site
720554008278	L13 binding site [polypeptide binding]; other site
720554008279	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
720554008280	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
720554008281	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
720554008282	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
720554008283	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554008284	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554008285	Integrase core domain; Region: rve; pfam00665
720554008286	Thymidylate synthase complementing protein; Region: Thy1; pfam02511
720554008287	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
720554008288	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
720554008289	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
720554008290	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
720554008291	active site
720554008292	dimer interface [polypeptide binding]; other site
720554008293	motif 1; other site
720554008294	motif 2; other site
720554008295	motif 3; other site
720554008296	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
720554008297	anticodon binding site; other site
720554008298	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
720554008299	ATP binding site [chemical binding]; other site
720554008300	Mg2+ binding site [ion binding]; other site
720554008301	G-X-G motif; other site
720554008302	Glycosyl hydrolase family 48; Region: Glyco_hydro_48; pfam02011
720554008303	endoglucanase; Region: PLN02308
720554008304	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554008305	Cellulose binding domain; Region: CBM_3; smart01067
720554008306	Cellulose binding domain; Region: CBM_3; pfam00942
720554008307	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554008308	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
720554008309	SLBB domain; Region: SLBB; pfam10531
720554008310	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
720554008311	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
720554008312	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
720554008313	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
720554008314	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
720554008315	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554008316	MULE transposase domain; Region: MULE; pfam10551
720554008317	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
720554008318	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554008319	Walker A/P-loop; other site
720554008320	ATP binding site [chemical binding]; other site
720554008321	Q-loop/lid; other site
720554008322	ABC transporter signature motif; other site
720554008323	Walker B; other site
720554008324	D-loop; other site
720554008325	H-loop/switch region; other site
720554008326	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554008327	MULE transposase domain; Region: MULE; pfam10551
720554008328	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
720554008329	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
720554008330	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554008331	Zn2+ binding site [ion binding]; other site
720554008332	Mg2+ binding site [ion binding]; other site
720554008333	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
720554008334	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
720554008335	active site
720554008336	(T/H)XGH motif; other site
720554008337	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
720554008338	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
720554008339	nucleotide binding site [chemical binding]; other site
720554008340	Alpha-L-arabinofuranosidase B (ABFB); Region: AbfB; pfam05270
720554008341	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
720554008342	active site
720554008343	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008344	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008345	GH3 auxin-responsive promoter; Region: GH3; pfam03321
720554008346	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
720554008347	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
720554008348	putative NAD(P) binding site [chemical binding]; other site
720554008349	active site
720554008350	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
720554008351	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
720554008352	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554008353	Coenzyme A binding pocket [chemical binding]; other site
720554008354	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
720554008355	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
720554008356	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
720554008357	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
720554008358	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
720554008359	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
720554008360	purine monophosphate binding site [chemical binding]; other site
720554008361	dimer interface [polypeptide binding]; other site
720554008362	putative catalytic residues [active]
720554008363	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
720554008364	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
720554008365	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
720554008366	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
720554008367	active site
720554008368	substrate binding site [chemical binding]; other site
720554008369	cosubstrate binding site; other site
720554008370	catalytic site [active]
720554008371	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
720554008372	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
720554008373	dimerization interface [polypeptide binding]; other site
720554008374	putative ATP binding site [chemical binding]; other site
720554008375	amidophosphoribosyltransferase; Provisional; Region: PRK05793
720554008376	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
720554008377	active site
720554008378	tetramer interface [polypeptide binding]; other site
720554008379	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554008380	active site
720554008381	AIR carboxylase; Region: AIRC; pfam00731
720554008382	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
720554008383	Predicted permeases [General function prediction only]; Region: COG0679
720554008384	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554008385	delta endotoxin, N-terminal domain; Region: Endotoxin_N; pfam03945
720554008386	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554008387	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554008388	Integrase core domain; Region: rve; pfam00665
720554008389	GMP synthase; Reviewed; Region: guaA; PRK00074
720554008390	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
720554008391	AMP/PPi binding site [chemical binding]; other site
720554008392	candidate oxyanion hole; other site
720554008393	catalytic triad [active]
720554008394	potential glutamine specificity residues [chemical binding]; other site
720554008395	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
720554008396	ATP Binding subdomain [chemical binding]; other site
720554008397	Ligand Binding sites [chemical binding]; other site
720554008398	Dimerization subdomain; other site
720554008399	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
720554008400	Protein of unknown function DUF111; Region: DUF111; pfam01969
720554008401	NCAIR mutase (PurE)-related proteins [General function prediction only]; Region: COG1691
720554008402	AIR carboxylase; Region: AIRC; smart01001
720554008403	Uncharacterized conserved protein [Function unknown]; Region: COG5495
720554008404	Rossmann-like domain; Region: Rossmann-like; pfam10727
720554008405	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
720554008406	peptide chain release factor 2; Provisional; Region: PRK05589
720554008407	This domain is found in peptide chain release factors; Region: PCRF; smart00937
720554008408	RF-1 domain; Region: RF-1; pfam00472
720554008409	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
720554008410	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554008411	non-specific DNA binding site [nucleotide binding]; other site
720554008412	salt bridge; other site
720554008413	sequence-specific DNA binding site [nucleotide binding]; other site
720554008414	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
720554008415	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
720554008416	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554008417	active site
720554008418	motif I; other site
720554008419	motif II; other site
720554008420	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554008421	hypothetical protein; Validated; Region: PRK07682
720554008422	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554008423	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554008424	homodimer interface [polypeptide binding]; other site
720554008425	catalytic residue [active]
720554008426	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
720554008427	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
720554008428	AsnC family; Region: AsnC_trans_reg; pfam01037
720554008429	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
720554008430	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
720554008431	catalytic residues [active]
720554008432	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
720554008433	putative homodimer interface [polypeptide binding]; other site
720554008434	putative homotetramer interface [polypeptide binding]; other site
720554008435	putative allosteric switch controlling residues; other site
720554008436	putative metal binding site [ion binding]; other site
720554008437	putative homodimer-homodimer interface [polypeptide binding]; other site
720554008438	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
720554008439	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
720554008440	putative homodimer interface [polypeptide binding]; other site
720554008441	putative active site pocket [active]
720554008442	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
720554008443	PHP family phosphoesterase with a Zn ribbon [General function prediction only]; Region: COG1379
720554008444	PHP-associated; Region: PHP_C; pfam13263
720554008445	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
720554008446	DNA binding site [nucleotide binding]
720554008447	4-hydroxy-2-oxovalerate aldolase-like, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA_like; cd07944
720554008448	active site
720554008449	catalytic residues [active]
720554008450	metal binding site [ion binding]; metal-binding site
720554008451	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
720554008452	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554008453	metal binding site [ion binding]; metal-binding site
720554008454	ligand binding site [chemical binding]; other site
720554008455	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
720554008456	metal binding site [ion binding]; metal-binding site
720554008457	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
720554008458	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
720554008459	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
720554008460	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; pfam09989
720554008461	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
720554008462	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
720554008463	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
720554008464	Catalytic site [active]
720554008465	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
720554008466	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
720554008467	intersubunit interface [polypeptide binding]; other site
720554008468	active site
720554008469	zinc binding site [ion binding]; other site
720554008470	Na+ binding site [ion binding]; other site
720554008471	6-phosphofructokinase; Provisional; Region: PRK14072
720554008472	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
720554008473	active site
720554008474	ADP/pyrophosphate binding site [chemical binding]; other site
720554008475	dimerization interface [polypeptide binding]; other site
720554008476	allosteric effector site; other site
720554008477	fructose-1,6-bisphosphate binding site; other site
720554008478	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
720554008479	Pyruvate formate lyase 1; Region: PFL1; cd01678
720554008480	coenzyme A binding site [chemical binding]; other site
720554008481	active site
720554008482	catalytic residues [active]
720554008483	glycine loop; other site
720554008484	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
720554008485	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554008486	FeS/SAM binding site; other site
720554008487	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554008488	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
720554008489	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
720554008490	Walker A motif; other site
720554008491	ATP binding site [chemical binding]; other site
720554008492	Walker B motif; other site
720554008493	AAA domain; Region: AAA_31; pfam13614
720554008494	PilZ domain; Region: PilZ; pfam07238
720554008495	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
720554008496	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
720554008497	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008498	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554008499	Walker A motif; other site
720554008500	ATP binding site [chemical binding]; other site
720554008501	Walker B motif; other site
720554008502	arginine finger; other site
720554008503	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008504	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554008505	Walker A motif; other site
720554008506	ATP binding site [chemical binding]; other site
720554008507	Walker B motif; other site
720554008508	arginine finger; other site
720554008509	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
720554008510	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
720554008511	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
720554008512	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
720554008513	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
720554008514	excinuclease ABC subunit B; Provisional; Region: PRK05298
720554008515	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554008516	ATP binding site [chemical binding]; other site
720554008517	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
720554008518	putative Mg++ binding site [ion binding]; other site
720554008519	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554008520	nucleotide binding region [chemical binding]; other site
720554008521	ATP-binding site [chemical binding]; other site
720554008522	Ultra-violet resistance protein B; Region: UvrB; pfam12344
720554008523	UvrB/uvrC motif; Region: UVR; pfam02151
720554008524	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
720554008525	AAA ATPase domain; Region: AAA_16; pfam13191
720554008526	Predicted ATPase [General function prediction only]; Region: COG3903
720554008527	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554008528	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008529	TPR motif; other site
720554008530	binding surface
720554008531	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554008532	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554008533	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008534	TPR motif; other site
720554008535	binding surface
720554008536	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554008537	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554008538	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554008539	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554008540	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554008541	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554008542	Beta-mannanase [Carbohydrate transport and metabolism]; Region: ManB; COG4124
720554008543	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008544	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554008545	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
720554008546	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554008547	dimer interface [polypeptide binding]; other site
720554008548	phosphorylation site [posttranslational modification]
720554008549	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554008550	ATP binding site [chemical binding]; other site
720554008551	Mg2+ binding site [ion binding]; other site
720554008552	G-X-G motif; other site
720554008553	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554008554	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554008555	active site
720554008556	phosphorylation site [posttranslational modification]
720554008557	intermolecular recognition site; other site
720554008558	dimerization interface [polypeptide binding]; other site
720554008559	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554008560	DNA binding site [nucleotide binding]
720554008561	TPR repeat; Region: TPR_11; pfam13414
720554008562	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008563	binding surface
720554008564	TPR motif; other site
720554008565	TPR repeat; Region: TPR_11; pfam13414
720554008566	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008567	binding surface
720554008568	TPR motif; other site
720554008569	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008570	Tetratricopeptide repeat; Region: TPR_16; pfam13432
720554008571	TPR motif; other site
720554008572	binding surface
720554008573	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008574	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554008575	Walker A motif; other site
720554008576	ATP binding site [chemical binding]; other site
720554008577	Walker B motif; other site
720554008578	arginine finger; other site
720554008579	SUKH-3 immunity protein; Region: SUKH-3; pfam14433
720554008580	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
720554008581	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
720554008582	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
720554008583	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008584	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008585	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
720554008586	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
720554008587	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
720554008588	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
720554008589	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554008590	FeS/SAM binding site; other site
720554008591	magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; Region: BchE; TIGR02026
720554008592	B12 binding domain; Region: B12-binding; pfam02310
720554008593	B12 binding site [chemical binding]; other site
720554008594	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554008595	FeS/SAM binding site; other site
720554008596	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554008597	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
720554008598	active site
720554008599	NTP binding site [chemical binding]; other site
720554008600	nucleic acid binding site [nucleotide binding]; other site
720554008601	B12 binding domain; Region: B12-binding; pfam02310
720554008602	B12 binding site [chemical binding]; other site
720554008603	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
720554008604	B12 binding domain; Region: B12-binding; pfam02310
720554008605	B12 binding site [chemical binding]; other site
720554008606	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
720554008607	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
720554008608	FeS/SAM binding site; other site
720554008609	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
720554008610	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
720554008611	Uncharacterized protein conserved in bacteria C-term(DUF2220); Region: DUF2220; pfam09983
720554008612	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
720554008613	DNA-binding interface [nucleotide binding]; DNA binding site
720554008614	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554008615	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554008616	putative active site [active]
720554008617	putative NTP binding site [chemical binding]; other site
720554008618	putative nucleic acid binding site [nucleotide binding]; other site
720554008619	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554008620	transposase/IS protein; Provisional; Region: PRK09183
720554008621	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554008622	Walker A motif; other site
720554008623	ATP binding site [chemical binding]; other site
720554008624	Walker B motif; other site
720554008625	arginine finger; other site
720554008626	Transposase; Region: HTH_Tnp_1; cl17663
720554008627	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554008628	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554008629	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
720554008630	RHS Repeat; Region: RHS_repeat; cl11982
720554008631	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
720554008632	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554008633	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
720554008634	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
720554008635	DDE domain; Region: DDE_Tnp_IS240; pfam13610
720554008636	Integrase core domain; Region: rve; pfam00665
720554008637	Integrase core domain; Region: rve_3; pfam13683
720554008638	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554008639	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
720554008640	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
720554008641	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
720554008642	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554008643	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554008644	Transposase; Region: HTH_Tnp_1; cl17663
720554008645	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554008646	MULE transposase domain; Region: MULE; pfam10551
720554008647	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008648	binding surface
720554008649	TPR motif; other site
720554008650	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
720554008651	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554008652	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554008653	Walker A/P-loop; other site
720554008654	ATP binding site [chemical binding]; other site
720554008655	Q-loop/lid; other site
720554008656	ABC transporter signature motif; other site
720554008657	Walker B; other site
720554008658	D-loop; other site
720554008659	H-loop/switch region; other site
720554008660	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554008661	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554008662	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554008663	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554008664	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
720554008665	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
720554008666	Putative transposase; Region: Y2_Tnp; pfam04986
720554008667	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554008668	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554008669	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554008670	Transposase; Region: HTH_Tnp_1; pfam01527
720554008671	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554008672	putative transposase OrfB; Reviewed; Region: PHA02517
720554008673	HTH-like domain; Region: HTH_21; pfam13276
720554008674	Integrase core domain; Region: rve; pfam00665
720554008675	Integrase core domain; Region: rve_3; pfam13683
720554008676	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747
720554008677	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
720554008678	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
720554008679	Transposase; Region: HTH_Tnp_1; cl17663
720554008680	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
720554008681	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008682	YtxH-like protein; Region: YtxH; pfam12732
720554008683	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
720554008684	E-class dimer interface [polypeptide binding]; other site
720554008685	P-class dimer interface [polypeptide binding]; other site
720554008686	active site
720554008687	Cu2+ binding site [ion binding]; other site
720554008688	Zn2+ binding site [ion binding]; other site
720554008689	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
720554008690	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
720554008691	CAP-like domain; other site
720554008692	active site
720554008693	primary dimer interface [polypeptide binding]; other site
720554008694	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair]; Region: GyrB; COG0187
720554008695	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
720554008696	Mg2+ binding site [ion binding]; other site
720554008697	G-X-G motif; other site
720554008698	DNA gyrase B; Region: DNA_gyraseB; pfam00204
720554008699	ATP binding site [chemical binding]; other site
720554008700	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
720554008701	active site
720554008702	metal binding site [ion binding]; metal-binding site
720554008703	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
720554008704	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
720554008705	Uncharacterized conserved protein [Function unknown]; Region: COG2966
720554008706	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
720554008707	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554008708	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
720554008709	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
720554008710	Bacterial SH3 domain; Region: SH3_3; cl17532
720554008711	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
720554008712	Spore germination protein; Region: Spore_permease; cl17796
720554008713	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
720554008714	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
720554008715	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
720554008716	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cd01494
720554008717	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
720554008718	catalytic residue [active]
720554008719	BioY family; Region: BioY; pfam02632
720554008720	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
720554008721	putative FMN binding site [chemical binding]; other site
720554008722	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
720554008723	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
720554008724	NADP binding site [chemical binding]; other site
720554008725	homodimer interface [polypeptide binding]; other site
720554008726	active site
720554008727	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
720554008728	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
720554008729	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554008730	S-adenosylmethionine binding site [chemical binding]; other site
720554008731	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
720554008732	homotrimer interaction site [polypeptide binding]; other site
720554008733	putative active site [active]
720554008734	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554008735	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554008736	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554008737	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
720554008738	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
720554008739	catalytic residues [active]
720554008740	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
720554008741	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
720554008742	Glyco_18 domain; Region: Glyco_18; smart00636
720554008743	active site
720554008744	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008745	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
720554008746	DEAD/DEAH box helicase; Region: DEAD; pfam00270
720554008747	DEAD_2; Region: DEAD_2; pfam06733
720554008748	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
720554008749	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
720554008750	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
720554008751	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554008752	metal-binding site [ion binding]
720554008753	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
720554008754	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
720554008755	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554008756	dimerization interface [polypeptide binding]; other site
720554008757	putative DNA binding site [nucleotide binding]; other site
720554008758	putative Zn2+ binding site [ion binding]; other site
720554008759	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
720554008760	beta-galactosidase; Region: BGL; TIGR03356
720554008761	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554008762	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554008763	metal binding site [ion binding]; metal-binding site
720554008764	active site
720554008765	I-site; other site
720554008766	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554008767	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554008768	Zn2+ binding site [ion binding]; other site
720554008769	Mg2+ binding site [ion binding]; other site
720554008770	L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; Region: FucI; COG2407
720554008771	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
720554008772	hexamer (dimer of trimers) interface [polypeptide binding]; other site
720554008773	trimer interface [polypeptide binding]; other site
720554008774	substrate binding site [chemical binding]; other site
720554008775	Mn binding site [ion binding]; other site
720554008776	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
720554008777	S-layer homology domain; Region: SLH; pfam00395
720554008778	S-layer homology domain; Region: SLH; pfam00395
720554008779	S-layer homology domain; Region: SLH; pfam00395
720554008780	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554008781	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554008782	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554008783	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554008784	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554008785	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554008786	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554008787	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
720554008788	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
720554008789	Right handed beta helix region; Region: Beta_helix; pfam13229
720554008790	flavodoxin; Provisional; Region: PRK06242
720554008791	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
720554008792	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554008793	hypothetical protein; Provisional; Region: PRK11770
720554008794	Domain of unknown function (DUF307); Region: DUF307; pfam03733
720554008795	Domain of unknown function (DUF307); Region: DUF307; pfam03733
720554008796	Uncharacterized conserved protein [Function unknown]; Region: COG0432
720554008797	endoglucanase; Region: PLN02420
720554008798	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554008799	Cellulose binding domain; Region: CBM_3; smart01067
720554008800	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008801	Late competence development protein ComFB; Region: ComFB; pfam10719
720554008802	endoglucanase; Region: PLN02308
720554008803	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554008804	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008805	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554008806	Domain of unknown function (DUF1835); Region: DUF1835; pfam08874
720554008807	Protein of unknown function; Region: DUF3658; pfam12395
720554008808	YibE/F-like protein; Region: YibE_F; pfam07907
720554008809	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
720554008810	Major Facilitator Superfamily; Region: MFS_1; pfam07690
720554008811	putative substrate translocation pore; other site
720554008812	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
720554008813	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08665
720554008814	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
720554008815	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
720554008816	active site
720554008817	dimer interface [polypeptide binding]; other site
720554008818	effector binding site; other site
720554008819	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
720554008820	TSCPD domain; Region: TSCPD; pfam12637
720554008821	Putative glycosyl hydrolase domain; Region: DUF4015; pfam13200
720554008822	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
720554008823	active site
720554008824	Fe-S cluster binding site [ion binding]; other site
720554008825	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
720554008826	Fe-S cluster binding site [ion binding]; other site
720554008827	active site
720554008828	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, gammaproteobacterial type; Region: rSAM_QueE_gams; TIGR04349
720554008829	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554008830	FeS/SAM binding site; other site
720554008831	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
720554008832	active site
720554008833	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
720554008834	Ligand Binding Site [chemical binding]; other site
720554008835	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
720554008836	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
720554008837	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
720554008838	metal-binding site [ion binding]
720554008839	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
720554008840	Transcriptional regulator [Transcription]; Region: LytR; COG1316
720554008841	L,L-diaminopimelate aminotransferase; Validated; Region: PRK07590
720554008842	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554008843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554008844	homodimer interface [polypeptide binding]; other site
720554008845	catalytic residue [active]
720554008846	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
720554008847	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
720554008848	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
720554008849	Predicted integral membrane protein [Function unknown]; Region: COG5542
720554008850	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
720554008851	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
720554008852	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
720554008853	Ligand binding site; other site
720554008854	Putative Catalytic site; other site
720554008855	DXD motif; other site
720554008856	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
720554008857	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
720554008858	GDP-binding site [chemical binding]; other site
720554008859	ACT binding site; other site
720554008860	IMP binding site; other site
720554008861	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
720554008862	Fumarase C-terminus; Region: Fumerase_C; cl00795
720554008863	fumarate hydratase; Provisional; Region: PRK06246
720554008864	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
720554008865	Ligand Binding Site [chemical binding]; other site
720554008866	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
720554008867	IHF - DNA interface [nucleotide binding]; other site
720554008868	IHF dimer interface [polypeptide binding]; other site
720554008869	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
720554008870	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554008871	active site
720554008872	phosphorylation site [posttranslational modification]
720554008873	intermolecular recognition site; other site
720554008874	dimerization interface [polypeptide binding]; other site
720554008875	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
720554008876	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
720554008877	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
720554008878	hinge; other site
720554008879	active site
720554008880	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554008881	active site
720554008882	dimerization interface [polypeptide binding]; other site
720554008883	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
720554008884	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
720554008885	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
720554008886	GEMM cis-regulatory element
720554008887	GEMM cis-regulatory element
720554008888	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554008889	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554008890	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008891	dockerin binding interface; other site
720554008892	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008893	dockerin binding interface; other site
720554008894	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008895	dockerin binding interface; other site
720554008896	S-layer homology domain; Region: SLH; pfam00395
720554008897	S-layer homology domain; Region: SLH; pfam00395
720554008898	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008899	dockerin binding interface; other site
720554008900	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008901	dockerin binding interface; other site
720554008902	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008903	dockerin binding interface; other site
720554008904	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008905	dockerin binding interface; other site
720554008906	S-layer homology domain; Region: SLH; pfam00395
720554008907	S-layer homology domain; Region: SLH; pfam00395
720554008908	S-layer homology domain; Region: SLH; pfam00395
720554008909	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008910	dockerin binding interface; other site
720554008911	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008912	dockerin binding interface; other site
720554008913	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008914	dockerin binding interface; other site
720554008915	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008916	dockerin binding interface; other site
720554008917	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
720554008918	dockerin binding interface; other site
720554008919	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008920	dockerin binding interface; other site
720554008921	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008922	dockerin binding interface; other site
720554008923	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008924	dockerin binding interface; other site
720554008925	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008926	dockerin binding interface; other site
720554008927	Cellulose binding domain; Region: CBM_3; pfam00942
720554008928	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008929	dockerin binding interface; other site
720554008930	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008931	dockerin binding interface; other site
720554008932	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008933	dockerin binding interface; other site
720554008934	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554008935	dockerin binding interface; other site
720554008936	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554008937	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
720554008938	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
720554008939	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554008940	motif II; other site
720554008941	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
720554008942	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
720554008943	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
720554008944	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
720554008945	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554008946	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
720554008947	phosphopeptide binding site; other site
720554008948	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554008949	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554008950	metal binding site [ion binding]; metal-binding site
720554008951	active site
720554008952	I-site; other site
720554008953	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554008954	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554008955	Zn2+ binding site [ion binding]; other site
720554008956	Mg2+ binding site [ion binding]; other site
720554008957	Rhomboid family; Region: Rhomboid; pfam01694
720554008958	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554008959	binding surface
720554008960	TPR motif; other site
720554008961	TPR repeat; Region: TPR_11; pfam13414
720554008962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554008963	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
720554008964	Walker A/P-loop; other site
720554008965	ATP binding site [chemical binding]; other site
720554008966	Q-loop/lid; other site
720554008967	ABC transporter signature motif; other site
720554008968	Walker B; other site
720554008969	D-loop; other site
720554008970	H-loop/switch region; other site
720554008971	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
720554008972	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554008973	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554008974	dimerization interface [polypeptide binding]; other site
720554008975	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554008976	dimer interface [polypeptide binding]; other site
720554008977	phosphorylation site [posttranslational modification]
720554008978	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554008979	ATP binding site [chemical binding]; other site
720554008980	Mg2+ binding site [ion binding]; other site
720554008981	G-X-G motif; other site
720554008982	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554008983	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554008984	active site
720554008985	phosphorylation site [posttranslational modification]
720554008986	intermolecular recognition site; other site
720554008987	dimerization interface [polypeptide binding]; other site
720554008988	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554008989	DNA binding site [nucleotide binding]
720554008990	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554008991	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554008992	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
720554008993	Walker A/P-loop; other site
720554008994	ATP binding site [chemical binding]; other site
720554008995	Q-loop/lid; other site
720554008996	ABC transporter signature motif; other site
720554008997	Walker B; other site
720554008998	D-loop; other site
720554008999	H-loop/switch region; other site
720554009000	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
720554009001	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
720554009002	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554009003	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
720554009004	Walker A motif; other site
720554009005	Walker A/P-loop; other site
720554009006	ATP binding site [chemical binding]; other site
720554009007	ATP binding site [chemical binding]; other site
720554009008	Walker B motif; other site
720554009009	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
720554009010	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
720554009011	NAD binding site [chemical binding]; other site
720554009012	dimer interface [polypeptide binding]; other site
720554009013	substrate binding site [chemical binding]; other site
720554009014	tetramer (dimer of dimers) interface [polypeptide binding]; other site
720554009015	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
720554009016	Malic enzyme, N-terminal domain; Region: malic; pfam00390
720554009017	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
720554009018	putative NAD(P) binding site [chemical binding]; other site
720554009019	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
720554009020	active site
720554009021	catalytic triad [active]
720554009022	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554009023	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554009024	Carbohydrate Binding Module family 35 (CBM35), pectate lyase-like; appended mainly to enzymes that bind mannan (Man), xylan, glucuronic acid (GlcA) and possibly glucans; Region: CBM35_pectate_lyase-like; cd04082
720554009025	Ca binding site [ion binding]; other site
720554009026	Ca binding site (active) [ion binding]; other site
720554009027	ligand binding site [chemical binding]; other site
720554009028	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
720554009029	active site
720554009030	catalytic triad [active]
720554009031	CAAX protease self-immunity; Region: Abi; pfam02517
720554009032	DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533
720554009033	ATP-binding cassette domain of MutS-like homolog; Region: ABC_MutS-like; cd03283
720554009034	Walker A/P-loop; other site
720554009035	ATP binding site [chemical binding]; other site
720554009036	Q-loop/lid; other site
720554009037	ABC transporter signature motif; other site
720554009038	Walker B; other site
720554009039	D-loop; other site
720554009040	H-loop/switch region; other site
720554009041	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
720554009042	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
720554009043	putative ligand binding site [chemical binding]; other site
720554009044	putative NAD binding site [chemical binding]; other site
720554009045	putative catalytic site [active]
720554009046	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
720554009047	L-serine binding site [chemical binding]; other site
720554009048	ACT domain interface; other site
720554009049	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
720554009050	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
720554009051	Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342
720554009052	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
720554009053	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554009054	dockerin binding interface; other site
720554009055	S-layer homology domain; Region: SLH; pfam00395
720554009056	S-layer homology domain; Region: SLH; pfam00395
720554009057	S-layer homology domain; Region: SLH; pfam00395
720554009058	Putative glycosyl hydrolase domain; Region: DUF4015; pfam13200
720554009059	Putative zinc-finger; Region: zf-HC2; pfam13490
720554009060	Sporulation and spore germination; Region: Germane; pfam10646
720554009061	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
720554009062	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554009063	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009064	DNA binding residues [nucleotide binding]
720554009065	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554009066	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554009067	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
720554009068	Walker A/P-loop; other site
720554009069	ATP binding site [chemical binding]; other site
720554009070	Q-loop/lid; other site
720554009071	ABC transporter signature motif; other site
720554009072	Walker B; other site
720554009073	D-loop; other site
720554009074	H-loop/switch region; other site
720554009075	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
720554009076	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554009077	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554009078	Walker A/P-loop; other site
720554009079	ATP binding site [chemical binding]; other site
720554009080	Q-loop/lid; other site
720554009081	ABC transporter signature motif; other site
720554009082	Walker B; other site
720554009083	D-loop; other site
720554009084	H-loop/switch region; other site
720554009085	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554009086	putative Zn2+ binding site [ion binding]; other site
720554009087	putative DNA binding site [nucleotide binding]; other site
720554009088	dimerization interface [polypeptide binding]; other site
720554009089	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1_2; cd06113
720554009090	dimer interface [polypeptide binding]; other site
720554009091	Citrate synthase; Region: Citrate_synt; pfam00285
720554009092	active site
720554009093	citrylCoA binding site [chemical binding]; other site
720554009094	oxalacetate/citrate binding site [chemical binding]; other site
720554009095	coenzyme A binding site [chemical binding]; other site
720554009096	catalytic triad [active]
720554009097	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
720554009098	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
720554009099	active site
720554009100	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554009101	active site
720554009102	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554009103	Phosphotransferase enzyme family; Region: APH; pfam01636
720554009104	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
720554009105	substrate binding site [chemical binding]; other site
720554009106	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
720554009107	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
720554009108	ATP-grasp domain; Region: ATP-grasp_4; cl17255
720554009109	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
720554009110	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
720554009111	ATP-grasp domain; Region: ATP-grasp_4; cl17255
720554009112	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
720554009113	IMP binding site; other site
720554009114	dimer interface [polypeptide binding]; other site
720554009115	interdomain contacts; other site
720554009116	partial ornithine binding site; other site
720554009117	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554009118	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
720554009119	active site
720554009120	motif I; other site
720554009121	motif II; other site
720554009122	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
720554009123	Protein of unknown function (DUF458); Region: DUF458; pfam04308
720554009124	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
720554009125	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554009126	dimerization interface [polypeptide binding]; other site
720554009127	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554009128	dimer interface [polypeptide binding]; other site
720554009129	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
720554009130	putative CheW interface [polypeptide binding]; other site
720554009131	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554009132	putative NADPH-dependent glutamate synthase small subunit; Provisional; Region: PRK12814
720554009133	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
720554009134	catalytic loop [active]
720554009135	iron binding site [ion binding]; other site
720554009136	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554009137	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
720554009138	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
720554009139	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
720554009140	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
720554009141	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
720554009142	RNA polymerase sigma-70 factor, TIGR02952 family; Region: Sig70_famx2
720554009143	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554009144	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009145	DNA binding residues [nucleotide binding]
720554009146	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
720554009147	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
720554009148	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
720554009149	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554009150	metal binding site [ion binding]; metal-binding site
720554009151	ligand binding site [chemical binding]; other site
720554009152	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
720554009153	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554009154	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554009155	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
720554009156	metal binding site [ion binding]; metal-binding site
720554009157	ligand binding site [chemical binding]; other site
720554009158	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
720554009159	Catalytic NodB homology domain of Clostridium thermocellum acetylxylan esterase and its bacterial homologs; Region: CE4_CtAXE_like; cd10954
720554009160	NodB motif; other site
720554009161	active site
720554009162	catalytic site [active]
720554009163	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554009164	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554009165	dimer interface [polypeptide binding]; other site
720554009166	phosphorylation site [posttranslational modification]
720554009167	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554009168	ATP binding site [chemical binding]; other site
720554009169	Mg2+ binding site [ion binding]; other site
720554009170	G-X-G motif; other site
720554009171	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554009172	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554009173	active site
720554009174	phosphorylation site [posttranslational modification]
720554009175	intermolecular recognition site; other site
720554009176	dimerization interface [polypeptide binding]; other site
720554009177	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554009178	DNA binding site [nucleotide binding]
720554009179	Rubrerythrin [Energy production and conversion]; Region: COG1592
720554009180	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
720554009181	binuclear metal center [ion binding]; other site
720554009182	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
720554009183	iron binding site [ion binding]; other site
720554009184	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
720554009185	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
720554009186	Phosphate transporter family; Region: PHO4; pfam01384
720554009187	Putative membrane peptidase family (DUF2324); Region: DUF2324; pfam10086
720554009188	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
720554009189	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; pfam03738
720554009190	Protein of unknown function (DUF327); Region: DUF327; cl00753
720554009191	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
720554009192	HSP70 interaction site [polypeptide binding]; other site
720554009193	Domain of unknown function (DUF955); Region: DUF955; pfam06114
720554009194	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
720554009195	non-specific DNA binding site [nucleotide binding]; other site
720554009196	salt bridge; other site
720554009197	sequence-specific DNA binding site [nucleotide binding]; other site
720554009198	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
720554009199	Family description; Region: UvrD_C_2; pfam13538
720554009200	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
720554009201	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
720554009202	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
720554009203	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
720554009204	HlyD family secretion protein; Region: HlyD_3; pfam13437
720554009205	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
720554009206	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
720554009207	putative active site [active]
720554009208	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
720554009209	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554009210	Walker A/P-loop; other site
720554009211	ATP binding site [chemical binding]; other site
720554009212	Q-loop/lid; other site
720554009213	ABC transporter signature motif; other site
720554009214	Walker B; other site
720554009215	D-loop; other site
720554009216	H-loop/switch region; other site
720554009217	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554009218	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554009219	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
720554009220	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187
720554009221	acyl-activating enzyme (AAE) consensus motif; other site
720554009222	AMP binding site [chemical binding]; other site
720554009223	active site
720554009224	CoA binding site [chemical binding]; other site
720554009225	methionine sulfoxide reductase A; Provisional; Region: PRK14054
720554009226	methionine sulfoxide reductase B; Provisional; Region: PRK00222
720554009227	SelR domain; Region: SelR; pfam01641
720554009228	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
720554009229	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554009230	NAD(P) binding site [chemical binding]; other site
720554009231	active site
720554009232	1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]; Region: GlgB; COG0296
720554009233	N-terminal Early set domain associated with the catalytic domain of eukaryotic glycogen branching enzyme (also called 1,4 alpha glucan branching enzyme); Region: E_set_GBE_euk_N; cd02854
720554009234	Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes; Region: AmyAc_bac_euk_BE; cd11321
720554009235	active site
720554009236	catalytic site [active]
720554009237	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
720554009238	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554009239	dockerin binding interface; other site
720554009240	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554009241	dockerin binding interface; other site
720554009242	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554009243	dockerin binding interface; other site
720554009244	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
720554009245	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
720554009246	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
720554009247	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
720554009248	acyl-activating enzyme (AAE) consensus motif; other site
720554009249	putative AMP binding site [chemical binding]; other site
720554009250	putative active site [active]
720554009251	putative CoA binding site [chemical binding]; other site
720554009252	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
720554009253	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554009254	dimerization interface [polypeptide binding]; other site
720554009255	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554009256	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554009257	dimer interface [polypeptide binding]; other site
720554009258	putative CheW interface [polypeptide binding]; other site
720554009259	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554009260	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554009261	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554009262	FIST N domain; Region: FIST; pfam08495
720554009263	FIST C domain; Region: FIST_C; pfam10442
720554009264	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
720554009265	dimerization interface [polypeptide binding]; other site
720554009266	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554009267	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554009268	dimer interface [polypeptide binding]; other site
720554009269	putative CheW interface [polypeptide binding]; other site
720554009270	Uncharacterized protein with conserved CXXC pairs [Function unknown]; Region: COG3862
720554009271	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
720554009272	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
720554009273	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
720554009274	NAD(P) binding pocket [chemical binding]; other site
720554009275	Predicted dehydrogenase [General function prediction only]; Region: COG0579
720554009276	hydroxyglutarate oxidase; Provisional; Region: PRK11728
720554009277	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
720554009278	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
720554009279	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
720554009280	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
720554009281	Ligand binding site; other site
720554009282	Putative Catalytic site; other site
720554009283	DXD motif; other site
720554009284	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
720554009285	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
720554009286	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554009287	NAD(P) binding site [chemical binding]; other site
720554009288	active site
720554009289	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
720554009290	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
720554009291	active site
720554009292	Predicted dehydrogenase [General function prediction only]; Region: COG0579
720554009293	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554009294	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554009295	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554009296	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554009297	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
720554009298	Ferritin-like domain; Region: Ferritin; pfam00210
720554009299	ferroxidase diiron center [ion binding]; other site
720554009300	Ecdysteroid kinase; Region: EcKinase; cl17738
720554009301	Hemerythrin-like domain; Region: Hr-like; cd12108
720554009302	Fe binding site [ion binding]; other site
720554009303	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
720554009304	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
720554009305	CysD dimerization site [polypeptide binding]; other site
720554009306	G1 box; other site
720554009307	putative GEF interaction site [polypeptide binding]; other site
720554009308	GTP/Mg2+ binding site [chemical binding]; other site
720554009309	Switch I region; other site
720554009310	G2 box; other site
720554009311	G3 box; other site
720554009312	Switch II region; other site
720554009313	G4 box; other site
720554009314	G5 box; other site
720554009315	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
720554009316	Domain III of Elongation factor (EF) Tu (EF-TU) and EF-G.  Elongation factors (EF) EF-Tu and EF-G participate in the elongation phase during protein biosynthesis on the ribosome. Their functional cycles depend on GTP binding and its hydrolysis. The EF-Tu...; Region: Translation_factor_III; cl02786
720554009317	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
720554009318	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
720554009319	Active Sites [active]
720554009320	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
720554009321	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
720554009322	Active Sites [active]
720554009323	ferredoxin-nitrite reductase; Reviewed; Region: nirA; PRK09566
720554009324	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
720554009325	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
720554009326	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
720554009327	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
720554009328	homodimer interface [polypeptide binding]; other site
720554009329	substrate-cofactor binding pocket; other site
720554009330	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554009331	catalytic residue [active]
720554009332	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554009333	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554009334	metal binding site [ion binding]; metal-binding site
720554009335	active site
720554009336	I-site; other site
720554009337	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
720554009338	AAA domain; Region: AAA_33; pfam13671
720554009339	AAA domain; Region: AAA_17; pfam13207
720554009340	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
720554009341	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
720554009342	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554009343	Radical SAM superfamily; Region: Radical_SAM; pfam04055
720554009344	FeS/SAM binding site; other site
720554009345	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
720554009346	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
720554009347	Predicted transcriptional regulator [Transcription]; Region: COG2378
720554009348	HTH domain; Region: HTH_11; pfam08279
720554009349	WYL domain; Region: WYL; pfam13280
720554009350	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
720554009351	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
720554009352	Penicillinase repressor; Region: Pencillinase_R; pfam03965
720554009353	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
720554009354	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554009355	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554009356	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
720554009357	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554009358	Zn2+ binding site [ion binding]; other site
720554009359	Mg2+ binding site [ion binding]; other site
720554009360	PilZ domain; Region: PilZ; pfam07238
720554009361	stage II sporulation protein E; Region: spore_II_E; TIGR02865
720554009362	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
720554009363	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
720554009364	aminoglycoside resistance protein; Provisional; Region: PRK13746
720554009365	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
720554009366	active site
720554009367	NTP binding site [chemical binding]; other site
720554009368	metal binding triad [ion binding]; metal-binding site
720554009369	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
720554009370	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554009371	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554009372	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554009373	transposase/IS protein; Provisional; Region: PRK09183
720554009374	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554009375	Walker A motif; other site
720554009376	ATP binding site [chemical binding]; other site
720554009377	Walker B motif; other site
720554009378	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554009379	Integrase core domain; Region: rve; pfam00665
720554009380	SUKH-3 immunity protein; Region: SUKH-3; pfam14433
720554009381	YwqJ-like deaminase; Region: YwqJ-deaminase; pfam14431
720554009382	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
720554009383	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
720554009384	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
720554009385	potential frameshift: common BLAST hit: gi|222530528|ref|YP_002574410.1| transglutaminase domain-containing protein
720554009386	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554009387	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554009388	Uncharacterized conserved protein [Function unknown]; Region: COG5316
720554009389	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
720554009390	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
720554009391	MgtE intracellular N domain; Region: MgtE_N; smart00924
720554009392	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
720554009393	Divalent cation transporter; Region: MgtE; pfam01769
720554009394	Cache domain; Region: Cache_1; pfam02743
720554009395	HAMP domain; Region: HAMP; pfam00672
720554009396	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554009397	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554009398	dimer interface [polypeptide binding]; other site
720554009399	putative CheW interface [polypeptide binding]; other site
720554009400	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
720554009401	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554009402	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554009403	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554009404	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
720554009405	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554009406	S-adenosylmethionine binding site [chemical binding]; other site
720554009407	Domain of unknown function (DUF3784); Region: DUF3784; pfam12650
720554009408	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
720554009409	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
720554009410	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
720554009411	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
720554009412	MASE1; Region: MASE1; cl17823
720554009413	Predicted membrane protein [Function unknown]; Region: COG1511
720554009414	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
720554009415	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
720554009416	trimer interface [polypeptide binding]; other site
720554009417	active site
720554009418	SdpI/YhfL protein family; Region: SdpI; pfam13630
720554009419	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554009420	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
720554009421	active site
720554009422	motif I; other site
720554009423	motif II; other site
720554009424	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
720554009425	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
720554009426	homodimer interface [polypeptide binding]; other site
720554009427	glycosyltransferase, MGT family; Region: MGT; TIGR01426
720554009428	active site
720554009429	TDP-binding site; other site
720554009430	acceptor substrate-binding pocket; other site
720554009431	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
720554009432	GIY-YIG motif/motif A; other site
720554009433	Transposase domain (DUF772); Region: DUF772; pfam05598
720554009434	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554009435	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554009436	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
720554009437	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
720554009438	Cache domain; Region: Cache_1; pfam02743
720554009439	HAMP domain; Region: HAMP; pfam00672
720554009440	dimerization interface [polypeptide binding]; other site
720554009441	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554009442	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554009443	dimer interface [polypeptide binding]; other site
720554009444	putative CheW interface [polypeptide binding]; other site
720554009445	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
720554009446	Helix-turn-helix domain; Region: HTH_38; pfam13936
720554009447	Integrase core domain; Region: rve; pfam00665
720554009448	Transposase domain (DUF772); Region: DUF772; pfam05598
720554009449	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554009450	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554009451	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
720554009452	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554009453	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554009454	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554009455	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
720554009456	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
720554009457	Transposase domain (DUF772); Region: DUF772; pfam05598
720554009458	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554009459	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554009460	Predicted membrane protein [Function unknown]; Region: COG2510
720554009461	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
720554009462	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
720554009463	Ligand binding site; other site
720554009464	metal-binding site
720554009465	Predicted ATPases of PP-loop superfamily [General function prediction only]; Region: COG2102
720554009466	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
720554009467	Ligand Binding Site [chemical binding]; other site
720554009468	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
720554009469	dimer interface [polypeptide binding]; other site
720554009470	substrate binding site [chemical binding]; other site
720554009471	ATP binding site [chemical binding]; other site
720554009472	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
720554009473	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
720554009474	motif II; other site
720554009475	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
720554009476	thiamine phosphate binding site [chemical binding]; other site
720554009477	active site
720554009478	pyrophosphate binding site [ion binding]; other site
720554009479	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
720554009480	substrate binding site [chemical binding]; other site
720554009481	multimerization interface [polypeptide binding]; other site
720554009482	ATP binding site [chemical binding]; other site
720554009483	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
720554009484	metal binding site [ion binding]; metal-binding site
720554009485	spermidine synthase; Provisional; Region: PRK00811
720554009486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554009487	S-adenosylmethionine binding site [chemical binding]; other site
720554009488	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
720554009489	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
720554009490	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
720554009491	Penicillinase repressor; Region: Pencillinase_R; cl17580
720554009492	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
720554009493	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
720554009494	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
720554009495	FtsX-like permease family; Region: FtsX; pfam02687
720554009496	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
720554009497	FtsX-like permease family; Region: FtsX; pfam02687
720554009498	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554009499	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554009500	Walker A/P-loop; other site
720554009501	ATP binding site [chemical binding]; other site
720554009502	Q-loop/lid; other site
720554009503	ABC transporter signature motif; other site
720554009504	Walker B; other site
720554009505	D-loop; other site
720554009506	H-loop/switch region; other site
720554009507	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554009508	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
720554009509	dimer interface [polypeptide binding]; other site
720554009510	phosphorylation site [posttranslational modification]
720554009511	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554009512	ATP binding site [chemical binding]; other site
720554009513	Mg2+ binding site [ion binding]; other site
720554009514	G-X-G motif; other site
720554009515	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554009516	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554009517	active site
720554009518	phosphorylation site [posttranslational modification]
720554009519	intermolecular recognition site; other site
720554009520	dimerization interface [polypeptide binding]; other site
720554009521	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554009522	DNA binding site [nucleotide binding]
720554009523	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
720554009524	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554009525	Coenzyme A binding pocket [chemical binding]; other site
720554009526	Radical SAM superfamily; Region: Radical_SAM; pfam04055
720554009527	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554009528	FeS/SAM binding site; other site
720554009529	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554009530	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
720554009531	catalytic residues [active]
720554009532	catalytic nucleophile [active]
720554009533	Recombinase; Region: Recombinase; pfam07508
720554009534	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554009535	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009536	DNA binding residues [nucleotide binding]
720554009537	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554009538	non-specific DNA binding site [nucleotide binding]; other site
720554009539	salt bridge; other site
720554009540	sequence-specific DNA binding site [nucleotide binding]; other site
720554009541	GEMM cis-regulatory element
720554009542	cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223
720554009543	Accessory gene regulator B; Region: AgrB; pfam04647
720554009544	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
720554009545	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554009546	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554009547	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554009548	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554009549	Chromate transporter; Region: Chromate_transp; pfam02417
720554009550	Chromate transporter; Region: Chromate_transp; pfam02417
720554009551	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
720554009552	ABC-2 type transporter; Region: ABC2_membrane; cl17235
720554009553	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
720554009554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
720554009555	Walker A/P-loop; other site
720554009556	ATP binding site [chemical binding]; other site
720554009557	Q-loop/lid; other site
720554009558	ABC transporter signature motif; other site
720554009559	Walker B; other site
720554009560	D-loop; other site
720554009561	H-loop/switch region; other site
720554009562	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
720554009563	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
720554009564	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
720554009565	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
720554009566	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
720554009567	MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149
720554009568	This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110
720554009569	P loop nucleotide binding; other site
720554009570	switch II; other site
720554009571	This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110
720554009572	P loop nucleotide binding; other site
720554009573	Ferredoxin [Energy production and conversion]; Region: COG1146
720554009574	switch II; other site
720554009575	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
720554009576	hypothetical protein; Provisional; Region: PRK06547
720554009577	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
720554009578	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
720554009579	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
720554009580	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
720554009581	trimerization site [polypeptide binding]; other site
720554009582	active site
720554009583	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554009584	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009585	DNA binding residues [nucleotide binding]
720554009586	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554009587	ATP binding site [chemical binding]; other site
720554009588	Mg2+ binding site [ion binding]; other site
720554009589	G-X-G motif; other site
720554009590	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
720554009591	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554009592	active site
720554009593	phosphorylation site [posttranslational modification]
720554009594	intermolecular recognition site; other site
720554009595	dimerization interface [polypeptide binding]; other site
720554009596	LytTr DNA-binding domain; Region: LytTR; smart00850
720554009597	GEMM cis-regulatory element
720554009598	Predicted RNA-binding protein; Region: RNA_bind_2; pfam10133
720554009599	Domain of unknown function (DUF3842); Region: DUF3842; pfam12953
720554009600	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
720554009601	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
720554009602	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
720554009603	ABC-ATPase subunit  interface; other site
720554009604	dimer interface [polypeptide binding]; other site
720554009605	putative PBP binding regions; other site
720554009606	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
720554009607	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
720554009608	intersubunit interface [polypeptide binding]; other site
720554009609	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
720554009610	Precorrin-8X methylmutase; Region: CbiC; pfam02570
720554009611	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; pfam02572
720554009612	cobyric acid synthase; Provisional; Region: PRK00784
720554009613	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554009614	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554009615	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
720554009616	catalytic triad [active]
720554009617	threonine-phosphate decarboxylase; Provisional; Region: PRK06358
720554009618	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554009619	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554009620	homodimer interface [polypeptide binding]; other site
720554009621	catalytic residue [active]
720554009622	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
720554009623	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
720554009624	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
720554009625	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
720554009626	catalytic triad [active]
720554009627	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
720554009628	active site
720554009629	putative homodimer interface [polypeptide binding]; other site
720554009630	SAM binding site [chemical binding]; other site
720554009631	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
720554009632	precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Region: CbiT; TIGR02469
720554009633	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
720554009634	putative active site [active]
720554009635	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
720554009636	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
720554009637	inhibitor-cofactor binding pocket; inhibition site
720554009638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554009639	catalytic residue [active]
720554009640	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
720554009641	dimer interface [polypeptide binding]; other site
720554009642	active site
720554009643	Schiff base residues; other site
720554009644	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
720554009645	active site
720554009646	SAM binding site [chemical binding]; other site
720554009647	homodimer interface [polypeptide binding]; other site
720554009648	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
720554009649	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
720554009650	active site
720554009651	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
720554009652	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
720554009653	domain interfaces; other site
720554009654	active site
720554009655	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; pfam02571
720554009656	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
720554009657	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
720554009658	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
720554009659	active site
720554009660	SAM binding site [chemical binding]; other site
720554009661	homodimer interface [polypeptide binding]; other site
720554009662	glutamyl-tRNA reductase; Validated; Region: hemA; PRK00676
720554009663	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
720554009664	tRNA; other site
720554009665	putative tRNA binding site [nucleotide binding]; other site
720554009666	putative NADP binding site [chemical binding]; other site
720554009667	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
720554009668	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
720554009669	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
720554009670	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
720554009671	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
720554009672	active site
720554009673	SAM binding site [chemical binding]; other site
720554009674	homodimer interface [polypeptide binding]; other site
720554009675	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
720554009676	active site
720554009677	SAM binding site [chemical binding]; other site
720554009678	homodimer interface [polypeptide binding]; other site
720554009679	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
720554009680	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13636
720554009681	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
720554009682	Walker A/P-loop; other site
720554009683	ATP binding site [chemical binding]; other site
720554009684	Q-loop/lid; other site
720554009685	ABC transporter signature motif; other site
720554009686	Walker B; other site
720554009687	D-loop; other site
720554009688	H-loop/switch region; other site
720554009689	Cobalt transport protein; Region: CbiQ; cl00463
720554009690	cobalt transport protein CbiN; Provisional; Region: PRK02898
720554009691	cobalt transport protein CbiM; Validated; Region: PRK08319
720554009692	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
720554009693	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
720554009694	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
720554009695	active site
720554009696	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
720554009697	Sm and related proteins; Region: Sm_like; cl00259
720554009698	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
720554009699	VRR-NUC domain; Region: VRR_NUC; pfam08774
720554009700	Uncharacterized conserved protein [Function unknown]; Region: COG4983
720554009701	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
720554009702	polymerase nucleotide-binding site; other site
720554009703	DNA-binding residues [nucleotide binding]; DNA binding site
720554009704	nucleotide binding site [chemical binding]; other site
720554009705	primase nucleotide-binding site [nucleotide binding]; other site
720554009706	Domain of unknown function (DUF4367); Region: DUF4367; pfam14285
720554009707	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554009708	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554009709	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009710	DNA binding residues [nucleotide binding]
720554009711	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554009712	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554009713	putative active site [active]
720554009714	putative NTP binding site [chemical binding]; other site
720554009715	putative nucleic acid binding site [nucleotide binding]; other site
720554009716	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554009717	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
720554009718	2',3'-cyclic-nucleotide 2'-phosphodiesterase; Region: CycNucDiestase; TIGR01390
720554009719	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
720554009720	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554009721	Walker A motif; other site
720554009722	ATP binding site [chemical binding]; other site
720554009723	Walker B motif; other site
720554009724	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554009725	Integrase core domain; Region: rve; pfam00665
720554009726	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
720554009727	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
720554009728	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554009729	ATP binding site [chemical binding]; other site
720554009730	putative Mg++ binding site [ion binding]; other site
720554009731	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
720554009732	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554009733	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
720554009734	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554009735	Virulence protein [General function prediction only]; Region: COG3943
720554009736	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
720554009737	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
720554009738	HsdM N-terminal domain; Region: HsdM_N; pfam12161
720554009739	Methyltransferase domain; Region: Methyltransf_26; pfam13659
720554009740	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
720554009741	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
720554009742	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554009743	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554009744	dimer interface [polypeptide binding]; other site
720554009745	phosphorylation site [posttranslational modification]
720554009746	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554009747	ATP binding site [chemical binding]; other site
720554009748	Mg2+ binding site [ion binding]; other site
720554009749	G-X-G motif; other site
720554009750	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554009751	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554009752	active site
720554009753	phosphorylation site [posttranslational modification]
720554009754	intermolecular recognition site; other site
720554009755	dimerization interface [polypeptide binding]; other site
720554009756	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554009757	DNA binding site [nucleotide binding]
720554009758	Domain of unknown function (DUF1413); Region: DUF1413; pfam07205
720554009759	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
720554009760	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
720554009761	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
720554009762	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
720554009763	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
720554009764	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554009765	Walker A motif; other site
720554009766	ATP binding site [chemical binding]; other site
720554009767	Walker B motif; other site
720554009768	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
720554009769	Integrase core domain; Region: rve; pfam00665
720554009770	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554009771	ATP binding site [chemical binding]; other site
720554009772	putative Mg++ binding site [ion binding]; other site
720554009773	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
720554009774	DNA methylase; Region: N6_N4_Mtase; pfam01555
720554009775	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554009776	ATP binding site [chemical binding]; other site
720554009777	putative Mg++ binding site [ion binding]; other site
720554009778	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554009779	nucleotide binding region [chemical binding]; other site
720554009780	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
720554009781	ATP-binding site [chemical binding]; other site
720554009782	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
720554009783	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554009784	non-specific DNA binding site [nucleotide binding]; other site
720554009785	salt bridge; other site
720554009786	sequence-specific DNA binding site [nucleotide binding]; other site
720554009787	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
720554009788	HTH-like domain; Region: HTH_21; pfam13276
720554009789	Integrase core domain; Region: rve; pfam00665
720554009790	Integrase core domain; Region: rve_3; pfam13683
720554009791	Transposase; Region: HTH_Tnp_1; pfam01527
720554009792	Winged helix-turn helix; Region: HTH_29; pfam13551
720554009793	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554009794	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554009795	putative active site [active]
720554009796	putative NTP binding site [chemical binding]; other site
720554009797	putative nucleic acid binding site [nucleotide binding]; other site
720554009798	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554009799	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554009800	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554009801	putative active site [active]
720554009802	putative NTP binding site [chemical binding]; other site
720554009803	putative nucleic acid binding site [nucleotide binding]; other site
720554009804	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554009805	RNA polymerase factor sigma C; Reviewed; Region: PRK09415
720554009806	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554009807	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009808	DNA binding residues [nucleotide binding]
720554009809	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
720554009810	Penicillinase repressor; Region: Pencillinase_R; pfam03965
720554009811	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554009812	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
720554009813	catalytic residues [active]
720554009814	catalytic nucleophile [active]
720554009815	Recombinase; Region: Recombinase; pfam07508
720554009816	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554009817	Recombinase; Region: Recombinase; pfam07508
720554009818	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554009819	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
720554009820	catalytic residues [active]
720554009821	catalytic nucleophile [active]
720554009822	Recombinase; Region: Recombinase; pfam07508
720554009823	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554009824	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
720554009825	amidase catalytic site [active]
720554009826	Zn binding residues [ion binding]; other site
720554009827	substrate binding site [chemical binding]; other site
720554009828	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554009829	Holin family; Region: Phage_holin_4; pfam05105
720554009830	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
720554009831	active site
720554009832	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
720554009833	potential frameshift: common BLAST hit: gi|332983315|ref|YP_004464756.1| phage minor structural protein
720554009834	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
720554009835	Phage tail protein; Region: Sipho_tail; pfam05709
720554009836	Phage-related minor tail protein [Function unknown]; Region: COG5280
720554009837	Abi-like protein; Region: Abi_2; pfam07751
720554009838	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
720554009839	VRR-NUC domain; Region: VRR_NUC; pfam08774
720554009840	HTH domain; Region: HTH_11; pfam08279
720554009841	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554009842	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554009843	Walker A/P-loop; other site
720554009844	ATP binding site [chemical binding]; other site
720554009845	Q-loop/lid; other site
720554009846	ABC transporter signature motif; other site
720554009847	Walker B; other site
720554009848	D-loop; other site
720554009849	H-loop/switch region; other site
720554009850	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
720554009851	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
720554009852	FtsX-like permease family; Region: FtsX; pfam02687
720554009853	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554009854	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554009855	ATP binding site [chemical binding]; other site
720554009856	Mg2+ binding site [ion binding]; other site
720554009857	G-X-G motif; other site
720554009858	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554009859	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554009860	active site
720554009861	phosphorylation site [posttranslational modification]
720554009862	intermolecular recognition site; other site
720554009863	dimerization interface [polypeptide binding]; other site
720554009864	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554009865	DNA binding site [nucleotide binding]
720554009866	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554009867	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554009868	Transposase; Region: HTH_Tnp_1; pfam01527
720554009869	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
720554009870	Transposase [DNA replication, recombination, and repair]; Region: COG5433
720554009871	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554009872	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
720554009873	putative active site [active]
720554009874	putative NTP binding site [chemical binding]; other site
720554009875	putative nucleic acid binding site [nucleotide binding]; other site
720554009876	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
720554009877	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
720554009878	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
720554009879	lipoprotein signal peptidase; Provisional; Region: PRK14787
720554009880	Heavy-metal-associated domain; Region: HMA; pfam00403
720554009881	metal-binding site [ion binding]
720554009882	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
720554009883	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
720554009884	metal-binding site [ion binding]
720554009885	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
720554009886	Soluble P-type ATPase [General function prediction only]; Region: COG4087
720554009887	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554009888	dimerization interface [polypeptide binding]; other site
720554009889	putative DNA binding site [nucleotide binding]; other site
720554009890	putative Zn2+ binding site [ion binding]; other site
720554009891	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554009892	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
720554009893	catalytic residues [active]
720554009894	catalytic nucleophile [active]
720554009895	Recombinase; Region: Recombinase; pfam07508
720554009896	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554009897	Recombinase; Region: Recombinase; pfam07508
720554009898	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
720554009899	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
720554009900	catalytic residues [active]
720554009901	catalytic nucleophile [active]
720554009902	Recombinase; Region: Recombinase; pfam07508
720554009903	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
720554009904	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
720554009905	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
720554009906	amidase catalytic site [active]
720554009907	Zn binding residues [ion binding]; other site
720554009908	substrate binding site [chemical binding]; other site
720554009909	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554009910	Holin family; Region: Phage_holin_4; pfam05105
720554009911	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
720554009912	active site
720554009913	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
720554009914	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
720554009915	Phage tail protein; Region: Sipho_tail; pfam05709
720554009916	Phage-related minor tail protein [Function unknown]; Region: COG5280
720554009917	phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603
720554009918	Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883
720554009919	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
720554009920	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
720554009921	oligomerization interface [polypeptide binding]; other site
720554009922	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
720554009923	Phage capsid family; Region: Phage_capsid; pfam05065
720554009924	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
720554009925	oligomer interface [polypeptide binding]; other site
720554009926	active site residues [active]
720554009927	Phage-related protein [Function unknown]; Region: COG4695
720554009928	Phage portal protein; Region: Phage_portal; pfam04860
720554009929	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
720554009930	terminase ATPase subunit; Provisional; Region: P; PHA02535
720554009931	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
720554009932	putative active site pocket [active]
720554009933	dimerization interface [polypeptide binding]; other site
720554009934	putative catalytic residue [active]
720554009935	Putative amidoligase enzyme; Region: Amidoligase_2; pfam12224
720554009936	Domain of unknown function (DUF4314); Region: DUF4314; pfam14192
720554009937	Putative amidoligase enzyme; Region: Amidoligase_2; pfam12224
720554009938	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
720554009939	ParB-like nuclease domain; Region: ParB; smart00470
720554009940	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
720554009941	DNA methylase; Region: N6_N4_Mtase; pfam01555
720554009942	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
720554009943	ParB-like nuclease domain; Region: ParBc; pfam02195
720554009944	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
720554009945	DNA methylase; Region: N6_N4_Mtase; pfam01555
720554009946	Phage terminase, small subunit; Region: Terminase_4; cl01525
720554009947	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
720554009948	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
720554009949	active site
720554009950	VRR-NUC domain; Region: VRR_NUC; pfam08774
720554009951	Uncharacterized conserved protein [Function unknown]; Region: COG4983
720554009952	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
720554009953	polymerase nucleotide-binding site; other site
720554009954	DNA-binding residues [nucleotide binding]; DNA binding site
720554009955	nucleotide binding site [chemical binding]; other site
720554009956	primase nucleotide-binding site [nucleotide binding]; other site
720554009957	Prophage antirepressor [Transcription]; Region: COG3617
720554009958	BRO family, N-terminal domain; Region: Bro-N; smart01040
720554009959	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
720554009960	bifunctional 3'-5' exonuclease/DNA polymerase; Provisional; Region: PRK14975
720554009961	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
720554009962	active site
720554009963	catalytic site [active]
720554009964	substrate binding site [chemical binding]; other site
720554009965	DNA polymerase A type from plastids of higher plants possibly involve in DNA replication or in the repair of errors occurring during replication; Region: DNA_pol_A_plastid_like; cd08640
720554009966	active site
720554009967	DNA binding site [nucleotide binding]
720554009968	catalytic site [active]
720554009969	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
720554009970	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
720554009971	ATP binding site [chemical binding]; other site
720554009972	putative Mg++ binding site [ion binding]; other site
720554009973	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
720554009974	nucleotide binding region [chemical binding]; other site
720554009975	ATP-binding site [chemical binding]; other site
720554009976	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554009977	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009978	DNA binding residues [nucleotide binding]
720554009979	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
720554009980	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554009981	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554009982	DNA binding residues [nucleotide binding]
720554009983	TRAM domain; Region: TRAM; cl01282
720554009984	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
720554009985	Predicted small integral membrane protein (DUF2165); Region: DUF2165; cl02290
720554009986	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554009987	S-adenosylmethionine binding site [chemical binding]; other site
720554009988	Methyltransferase domain; Region: Methyltransf_11; pfam08241
720554009989	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
720554009990	RibD C-terminal domain; Region: RibD_C; cl17279
720554009991	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
720554009992	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
720554009993	ArsC family; Region: ArsC; pfam03960
720554009994	putative ArsC-like catalytic residues; other site
720554009995	putative TRX-like catalytic residues [active]
720554009996	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
720554009997	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554009998	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554009999	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554010000	DNA binding residues [nucleotide binding]
720554010001	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
720554010002	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
720554010003	NAD(P) binding site [chemical binding]; other site
720554010004	catalytic residues [active]
720554010005	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
720554010006	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
720554010007	active site
720554010008	NAD binding site [chemical binding]; other site
720554010009	metal binding site [ion binding]; metal-binding site
720554010010	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
720554010011	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
720554010012	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554010013	DEAD-like helicases superfamily; Region: DEXDc; smart00487
720554010014	Walker A motif; other site
720554010015	ATP binding site [chemical binding]; other site
720554010016	Walker B motif; other site
720554010017	arginine finger; other site
720554010018	Nitroreductase family; Region: Nitroreductase; pfam00881
720554010019	FMN binding site [chemical binding]; other site
720554010020	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
720554010021	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
720554010022	dimer interface [polypeptide binding]; other site
720554010023	flavodoxin; Provisional; Region: PRK06242
720554010024	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
720554010025	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
720554010026	Walker A/P-loop; other site
720554010027	ATP binding site [chemical binding]; other site
720554010028	Q-loop/lid; other site
720554010029	ABC transporter signature motif; other site
720554010030	Walker B; other site
720554010031	D-loop; other site
720554010032	H-loop/switch region; other site
720554010033	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554010034	dimer interface [polypeptide binding]; other site
720554010035	conserved gate region; other site
720554010036	putative PBP binding loops; other site
720554010037	ABC-ATPase subunit interface; other site
720554010038	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
720554010039	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554010040	substrate binding pocket [chemical binding]; other site
720554010041	membrane-bound complex binding site; other site
720554010042	hinge residues; other site
720554010043	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
720554010044	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554010045	non-specific DNA binding site [nucleotide binding]; other site
720554010046	salt bridge; other site
720554010047	sequence-specific DNA binding site [nucleotide binding]; other site
720554010048	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
720554010049	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
720554010050	DNA binding site [nucleotide binding]
720554010051	active site
720554010052	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
720554010053	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
720554010054	substrate binding pocket [chemical binding]; other site
720554010055	membrane-bound complex binding site; other site
720554010056	hinge residues; other site
720554010057	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
720554010058	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
720554010059	Walker A/P-loop; other site
720554010060	ATP binding site [chemical binding]; other site
720554010061	Q-loop/lid; other site
720554010062	ABC transporter signature motif; other site
720554010063	Walker B; other site
720554010064	D-loop; other site
720554010065	H-loop/switch region; other site
720554010066	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
720554010067	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554010068	dimer interface [polypeptide binding]; other site
720554010069	conserved gate region; other site
720554010070	putative PBP binding loops; other site
720554010071	ABC-ATPase subunit interface; other site
720554010072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554010073	dimer interface [polypeptide binding]; other site
720554010074	conserved gate region; other site
720554010075	putative PBP binding loops; other site
720554010076	ABC-ATPase subunit interface; other site
720554010077	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554010078	MULE transposase domain; Region: MULE; pfam10551
720554010079	Predicted transcriptional regulators [Transcription]; Region: COG1733
720554010080	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554010081	dimerization interface [polypeptide binding]; other site
720554010082	putative DNA binding site [nucleotide binding]; other site
720554010083	putative Zn2+ binding site [ion binding]; other site
720554010084	Putative arginyl-tRNA:protein arginylyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG2935
720554010085	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
720554010086	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
720554010087	dimer interface [polypeptide binding]; other site
720554010088	conserved gate region; other site
720554010089	putative PBP binding loops; other site
720554010090	ABC-ATPase subunit interface; other site
720554010091	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
720554010092	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
720554010093	Walker A/P-loop; other site
720554010094	ATP binding site [chemical binding]; other site
720554010095	Q-loop/lid; other site
720554010096	ABC transporter signature motif; other site
720554010097	Walker B; other site
720554010098	D-loop; other site
720554010099	H-loop/switch region; other site
720554010100	Transcriptional regulator; Region: Rrf2; cl17282
720554010101	Rrf2 family protein; Region: rrf2_super; TIGR00738
720554010102	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554010103	Coenzyme A binding pocket [chemical binding]; other site
720554010104	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554010105	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554010106	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
720554010107	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
720554010108	Transposase domain (DUF772); Region: DUF772; pfam05598
720554010109	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554010110	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554010111	transposase/IS protein; Provisional; Region: PRK09183
720554010112	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554010113	Walker A motif; other site
720554010114	ATP binding site [chemical binding]; other site
720554010115	Walker B motif; other site
720554010116	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554010117	MULE transposase domain; Region: MULE; pfam10551
720554010118	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554010119	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
720554010120	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
720554010121	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554010122	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554010123	Walker A/P-loop; other site
720554010124	ATP binding site [chemical binding]; other site
720554010125	Q-loop/lid; other site
720554010126	ABC transporter signature motif; other site
720554010127	Walker B; other site
720554010128	D-loop; other site
720554010129	H-loop/switch region; other site
720554010130	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
720554010131	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
720554010132	FtsX-like permease family; Region: FtsX; pfam02687
720554010133	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
720554010134	FtsX-like permease family; Region: FtsX; pfam02687
720554010135	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
720554010136	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
720554010137	Protein of unknown function (DUF1700); Region: DUF1700; pfam08006
720554010138	Predicted transcriptional regulators [Transcription]; Region: COG1695
720554010139	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
720554010140	putative DNA binding site [nucleotide binding]; other site
720554010141	putative Zn2+ binding site [ion binding]; other site
720554010142	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554010143	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554010144	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554010145	potential frameshift: common BLAST hit: gi|346980573|ref|YP_001039164.2| transposase IS3/IS911
720554010146	Transposase; Region: HTH_Tnp_1; pfam01527
720554010147	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
720554010148	putative transposase OrfB; Reviewed; Region: PHA02517
720554010149	HTH-like domain; Region: HTH_21; pfam13276
720554010150	Integrase core domain; Region: rve; pfam00665
720554010151	Integrase core domain; Region: rve_3; pfam13683
720554010152	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
720554010153	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
720554010154	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
720554010155	catalytic triad [active]
720554010156	Methyltransferase domain; Region: Methyltransf_31; pfam13847
720554010157	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554010158	S-adenosylmethionine binding site [chemical binding]; other site
720554010159	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
720554010160	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
720554010161	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
720554010162	Double zinc ribbon; Region: DZR; pfam12773
720554010163	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
720554010164	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
720554010165	FlgN protein; Region: FlgN; pfam05130
720554010166	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
720554010167	Peptidase family M23; Region: Peptidase_M23; pfam01551
720554010168	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
720554010169	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
720554010170	Sporulation protein YunB (Spo_YunB); Region: Spore_YunB; cl09783
720554010171	Transglycosylase; Region: Transgly; pfam00912
720554010172	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
720554010173	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
720554010174	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
720554010175	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554010176	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554010177	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
720554010178	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
720554010179	FtsX-like permease family; Region: FtsX; pfam02687
720554010180	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
720554010181	HlyD family secretion protein; Region: HlyD_3; pfam13437
720554010182	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
720554010183	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
720554010184	Walker A/P-loop; other site
720554010185	ATP binding site [chemical binding]; other site
720554010186	Q-loop/lid; other site
720554010187	ABC transporter signature motif; other site
720554010188	Walker B; other site
720554010189	D-loop; other site
720554010190	H-loop/switch region; other site
720554010191	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
720554010192	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
720554010193	Outer membrane efflux protein; Region: OEP; pfam02321
720554010194	gamma-glutamyl kinase; Provisional; Region: PRK05429
720554010195	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
720554010196	nucleotide binding site [chemical binding]; other site
720554010197	homotetrameric interface [polypeptide binding]; other site
720554010198	putative phosphate binding site [ion binding]; other site
720554010199	putative allosteric binding site; other site
720554010200	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
720554010201	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
720554010202	GGGtGRT protein; Region: GGGtGRT; pfam14057
720554010203	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
720554010204	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
720554010205	Protein of unknown function, DUF486; Region: DUF486; cl01236
720554010206	Carbohydrate binding domain; Region: CBM_25; smart01066
720554010207	aconitate hydratase; Validated; Region: PRK07229
720554010208	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Bact; cd01585
720554010209	substrate binding site [chemical binding]; other site
720554010210	ligand binding site [chemical binding]; other site
720554010211	Bacterial Aconitase-like swivel domain. Aconitase (aconitate hydratase or citrate hydrolyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle.  Cis-aconitate is formed as an intermediate product during the course...; Region: AcnA_Bact_Swivel; cd01579
720554010212	substrate binding site [chemical binding]; other site
720554010213	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1_2; cd06113
720554010214	dimer interface [polypeptide binding]; other site
720554010215	Citrate synthase; Region: Citrate_synt; pfam00285
720554010216	active site
720554010217	citrylCoA binding site [chemical binding]; other site
720554010218	oxalacetate/citrate binding site [chemical binding]; other site
720554010219	coenzyme A binding site [chemical binding]; other site
720554010220	catalytic triad [active]
720554010221	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
720554010222	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
720554010223	DNA-binding site [nucleotide binding]; DNA binding site
720554010224	FCD domain; Region: FCD; pfam07729
720554010225	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
720554010226	AAA domain; Region: AAA_32; pfam13654
720554010227	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554010228	Walker A motif; other site
720554010229	ATP binding site [chemical binding]; other site
720554010230	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
720554010231	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
720554010232	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
720554010233	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
720554010234	Coenzyme A binding pocket [chemical binding]; other site
720554010235	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
720554010236	Glycoprotease family; Region: Peptidase_M22; pfam00814
720554010237	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
720554010238	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
720554010239	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
720554010240	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
720554010241	active site
720554010242	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
720554010243	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
720554010244	putative substrate translocation pore; other site
720554010245	FtsH Extracellular; Region: FtsH_ext; pfam06480
720554010246	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554010247	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
720554010248	Walker A motif; other site
720554010249	ATP binding site [chemical binding]; other site
720554010250	Walker B motif; other site
720554010251	arginine finger; other site
720554010252	Predicted transcriptional regulators [Transcription]; Region: COG1695
720554010253	Transcriptional regulator PadR-like family; Region: PadR; cl17335
720554010254	Protein of unknown function (DUF2812); Region: DUF2812; pfam11193
720554010255	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
720554010256	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
720554010257	active site
720554010258	catalytic tetrad [active]
720554010259	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554010260	Transposase, Mutator family; Region: Transposase_mut; pfam00872
720554010261	MULE transposase domain; Region: MULE; pfam10551
720554010262	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
720554010263	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
720554010264	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
720554010265	pentamer interface [polypeptide binding]; other site
720554010266	dodecaamer interface [polypeptide binding]; other site
720554010267	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
720554010268	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
720554010269	DNA binding residues [nucleotide binding]
720554010270	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
720554010271	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
720554010272	23S rRNA interface [nucleotide binding]; other site
720554010273	L3 interface [polypeptide binding]; other site
720554010274	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
720554010275	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
720554010276	dimerization interface 3.5A [polypeptide binding]; other site
720554010277	active site
720554010278	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
720554010279	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
720554010280	nucleotide binding site [chemical binding]; other site
720554010281	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
720554010282	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
720554010283	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13637
720554010284	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
720554010285	Walker A/P-loop; other site
720554010286	ATP binding site [chemical binding]; other site
720554010287	Q-loop/lid; other site
720554010288	ABC transporter signature motif; other site
720554010289	Walker B; other site
720554010290	D-loop; other site
720554010291	H-loop/switch region; other site
720554010292	Methyltransferase domain; Region: Methyltransf_31; pfam13847
720554010293	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554010294	S-adenosylmethionine binding site [chemical binding]; other site
720554010295	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633
720554010296	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
720554010297	Walker A/P-loop; other site
720554010298	ATP binding site [chemical binding]; other site
720554010299	Q-loop/lid; other site
720554010300	ABC transporter signature motif; other site
720554010301	Walker B; other site
720554010302	D-loop; other site
720554010303	H-loop/switch region; other site
720554010304	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
720554010305	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
720554010306	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
720554010307	alphaNTD homodimer interface [polypeptide binding]; other site
720554010308	alphaNTD - beta interaction site [polypeptide binding]; other site
720554010309	alphaNTD - beta' interaction site [polypeptide binding]; other site
720554010310	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
720554010311	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
720554010312	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
720554010313	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
720554010314	RNA binding surface [nucleotide binding]; other site
720554010315	30S ribosomal protein S11; Validated; Region: PRK05309
720554010316	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
720554010317	30S ribosomal protein S13; Region: bact_S13; TIGR03631
720554010318	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
720554010319	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
720554010320	rRNA binding site [nucleotide binding]; other site
720554010321	predicted 30S ribosome binding site; other site
720554010322	KOW motif of Ribosomal Protein L14; Region: KOW_RPL14; cd06088
720554010323	RNA binding site [nucleotide binding]; other site
720554010324	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
720554010325	active site
720554010326	adenylate kinase; Reviewed; Region: adk; PRK00279
720554010327	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
720554010328	AMP-binding site [chemical binding]; other site
720554010329	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
720554010330	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
720554010331	SecY translocase; Region: SecY; pfam00344
720554010332	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
720554010333	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
720554010334	23S rRNA binding site [nucleotide binding]; other site
720554010335	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
720554010336	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
720554010337	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
720554010338	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
720554010339	5S rRNA interface [nucleotide binding]; other site
720554010340	L27 interface [polypeptide binding]; other site
720554010341	23S rRNA interface [nucleotide binding]; other site
720554010342	L5 interface [polypeptide binding]; other site
720554010343	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
720554010344	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
720554010345	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
720554010346	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
720554010347	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
720554010348	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
720554010349	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
720554010350	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
720554010351	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
720554010352	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
720554010353	RNA binding site [nucleotide binding]; other site
720554010354	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
720554010355	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
720554010356	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
720554010357	23S rRNA interface [nucleotide binding]; other site
720554010358	putative translocon interaction site; other site
720554010359	signal recognition particle (SRP54) interaction site; other site
720554010360	L23 interface [polypeptide binding]; other site
720554010361	trigger factor interaction site; other site
720554010362	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
720554010363	23S rRNA interface [nucleotide binding]; other site
720554010364	5S rRNA interface [nucleotide binding]; other site
720554010365	putative antibiotic binding site [chemical binding]; other site
720554010366	L25 interface [polypeptide binding]; other site
720554010367	L27 interface [polypeptide binding]; other site
720554010368	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
720554010369	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
720554010370	G-X-X-G motif; other site
720554010371	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
720554010372	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
720554010373	putative translocon binding site; other site
720554010374	protein-rRNA interface [nucleotide binding]; other site
720554010375	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
720554010376	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
720554010377	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
720554010378	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
720554010379	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
720554010380	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
720554010381	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
720554010382	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
720554010383	Predicted membrane protein [Function unknown]; Region: XynA; COG2314
720554010384	stage V sporulation protein B; Region: spore_V_B; TIGR02900
720554010385	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
720554010386	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
720554010387	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
720554010388	Mg2+ binding site [ion binding]; other site
720554010389	G-X-G motif; other site
720554010390	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
720554010391	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554010392	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
720554010393	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554010394	DNA binding residues [nucleotide binding]
720554010395	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
720554010396	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
720554010397	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
720554010398	anti sigma factor interaction site; other site
720554010399	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
720554010400	regulatory phosphorylation site [posttranslational modification]; other site
720554010401	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
720554010402	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
720554010403	dimer interface [polypeptide binding]; other site
720554010404	putative anticodon binding site; other site
720554010405	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
720554010406	motif 1; other site
720554010407	active site
720554010408	motif 2; other site
720554010409	motif 3; other site
720554010410	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
720554010411	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
720554010412	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
720554010413	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554010414	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in  bacterial endospore germination.  CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells.  SleB translocates across the...; Region: GH18_CFLE_spore_hydrolase; cd02874
720554010415	active site
720554010416	PilZ domain; Region: PilZ; pfam07238
720554010417	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
720554010418	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
720554010419	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; pfam00759
720554010420	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010421	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010422	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
720554010423	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
720554010424	ring oligomerisation interface [polypeptide binding]; other site
720554010425	ATP/Mg binding site [chemical binding]; other site
720554010426	stacking interactions; other site
720554010427	hinge regions; other site
720554010428	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
720554010429	oligomerisation interface [polypeptide binding]; other site
720554010430	mobile loop; other site
720554010431	roof hairpin; other site
720554010432	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010433	Divergent AAA domain; Region: AAA_4; pfam04326
720554010434	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
720554010435	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
720554010436	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
720554010437	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
720554010438	metal binding site [ion binding]; metal-binding site
720554010439	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
720554010440	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
720554010441	substrate binding site [chemical binding]; other site
720554010442	glutamase interaction surface [polypeptide binding]; other site
720554010443	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
720554010444	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
720554010445	catalytic residues [active]
720554010446	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
720554010447	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
720554010448	putative active site [active]
720554010449	oxyanion strand; other site
720554010450	catalytic triad [active]
720554010451	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
720554010452	ATP binding site [chemical binding]; other site
720554010453	active site
720554010454	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
720554010455	substrate binding site [chemical binding]; other site
720554010456	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
720554010457	putative active site pocket [active]
720554010458	4-fold oligomerization interface [polypeptide binding]; other site
720554010459	metal binding residues [ion binding]; metal-binding site
720554010460	3-fold/trimer interface [polypeptide binding]; other site
720554010461	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
720554010462	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
720554010463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554010464	homodimer interface [polypeptide binding]; other site
720554010465	catalytic residue [active]
720554010466	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
720554010467	histidinol dehydrogenase; Region: hisD; TIGR00069
720554010468	NAD binding site [chemical binding]; other site
720554010469	dimerization interface [polypeptide binding]; other site
720554010470	product binding site; other site
720554010471	substrate binding site [chemical binding]; other site
720554010472	zinc binding site [ion binding]; other site
720554010473	catalytic residues [active]
720554010474	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
720554010475	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
720554010476	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
720554010477	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
720554010478	dimer interface [polypeptide binding]; other site
720554010479	motif 1; other site
720554010480	active site
720554010481	motif 2; other site
720554010482	motif 3; other site
720554010483	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
720554010484	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
720554010485	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010486	conserved hypothetical integral membrane protein; Region: TIGR03766
720554010487	Transposase domain (DUF772); Region: DUF772; pfam05598
720554010488	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
720554010489	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
720554010490	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
720554010491	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
720554010492	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
720554010493	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
720554010494	diiron binding motif [ion binding]; other site
720554010495	CCC1-related domain of ferritin; Region: Ferritin_CCC1_C; cd02431
720554010496	S-layer homology domain; Region: SLH; pfam00395
720554010497	S-layer homology domain; Region: SLH; pfam00395
720554010498	S-layer homology domain; Region: SLH; pfam00395
720554010499	Intracellular proteinase inhibitor; Region: BsuPI; pfam12690
720554010500	Intracellular proteinase inhibitor; Region: BsuPI; pfam12690
720554010501	Intracellular proteinase inhibitor; Region: BsuPI; pfam12690
720554010502	Intracellular proteinase inhibitor; Region: BsuPI; pfam12690
720554010503	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
720554010504	Part of AAA domain; Region: AAA_19; pfam13245
720554010505	Family description; Region: UvrD_C_2; pfam13538
720554010506	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
720554010507	30S subunit binding site; other site
720554010508	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
720554010509	Nitrogen regulatory protein P-II; Region: P-II; smart00938
720554010510	Ammonium Transporter Family; Region: Ammonium_transp; cl03012
720554010511	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
720554010512	active site
720554010513	phosphorylation site [posttranslational modification]
720554010514	intermolecular recognition site; other site
720554010515	dimerization interface [polypeptide binding]; other site
720554010516	ANTAR domain; Region: ANTAR; pfam03861
720554010517	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
720554010518	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
720554010519	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
720554010520	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
720554010521	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
720554010522	DXD motif; other site
720554010523	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
720554010524	DNA methylase; Region: N6_N4_Mtase; cl17433
720554010525	DNA methylase; Region: N6_N4_Mtase; pfam01555
720554010526	DNA methylase; Region: N6_N4_Mtase; cl17433
720554010527	CAAX protease self-immunity; Region: Abi; pfam02517
720554010528	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554010529	non-specific DNA binding site [nucleotide binding]; other site
720554010530	salt bridge; other site
720554010531	sequence-specific DNA binding site [nucleotide binding]; other site
720554010532	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
720554010533	Catalytic site [active]
720554010534	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554010535	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554010536	metal binding site [ion binding]; metal-binding site
720554010537	active site
720554010538	I-site; other site
720554010539	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
720554010540	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
720554010541	Zn2+ binding site [ion binding]; other site
720554010542	Mg2+ binding site [ion binding]; other site
720554010543	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
720554010544	Cellulose binding domain; Region: CBM_3; pfam00942
720554010545	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
720554010546	Putative catalytic NodB homology domain of uncharacterized prokaryotic polysaccharide deacetylases which consist of a 6-stranded beta/alpha barrel; Region: CE4_DAC_u1_6s; cd10970
720554010547	putative active site [active]
720554010548	putative metal binding site [ion binding]; other site
720554010549	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
720554010550	Putative catalytic NodB homology domain of uncharacterized prokaryotic polysaccharide deacetylases which consist of a 6-stranded beta/alpha barrel; Region: CE4_DAC_u1_6s; cd10970
720554010551	putative active site [active]
720554010552	putative metal binding site [ion binding]; other site
720554010553	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
720554010554	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
720554010555	NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family; Region: EDH_00030; TIGR04180
720554010556	NAD binding site [chemical binding]; other site
720554010557	substrate binding site [chemical binding]; other site
720554010558	active site
720554010559	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
720554010560	NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_2; cd06426
720554010561	Substrate binding site; other site
720554010562	metal-binding site
720554010563	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554010564	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
720554010565	NAD(P) binding site [chemical binding]; other site
720554010566	active site
720554010567	Predicted membrane protein [Function unknown]; Region: COG4267
720554010568	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_3; cd03813
720554010569	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
720554010570	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
720554010571	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554010572	NAD(P) binding site [chemical binding]; other site
720554010573	active site
720554010574	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
720554010575	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
720554010576	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
720554010577	FeS/SAM binding site; other site
720554010578	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
720554010579	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010580	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010581	Serpin (serine protease inhibitor); Region: Serpin; pfam00079
720554010582	serpin-like protein; Provisional; Region: PHA02660
720554010583	reactive center loop; other site
720554010584	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
720554010585	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
720554010586	acyl-activating enzyme (AAE) consensus motif; other site
720554010587	putative AMP binding site [chemical binding]; other site
720554010588	putative active site [active]
720554010589	putative CoA binding site [chemical binding]; other site
720554010590	Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168
720554010591	Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480
720554010592	G1 box; other site
720554010593	putative GEF interaction site [polypeptide binding]; other site
720554010594	GTP/Mg2+ binding site [chemical binding]; other site
720554010595	Switch I region; other site
720554010596	G2 box; other site
720554010597	G3 box; other site
720554010598	Switch II region; other site
720554010599	G4 box; other site
720554010600	G5 box; other site
720554010601	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
720554010602	EF-G_domain IV_RPP domain is a part of bacterial ribosomal protected proteins (RPP) family. RPPs such as tetracycline resistance proteins Tet(M) and Tet(O) mediate tetracycline resistance in both gram-positive and -negative species. Tetracyclines inhibit...; Region: Tet_like_IV; cd01684
720554010603	Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711
720554010604	YacP-like NYN domain; Region: NYN_YacP; pfam05991
720554010605	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
720554010606	putative ADP-ribose binding site [chemical binding]; other site
720554010607	putative active site [active]
720554010608	VbhA antitoxin and related proteins; Region: VbhA_like; cd11586
720554010609	FIC domain binding interface [polypeptide binding]; other site
720554010610	Fic/DOC family; Region: Fic; cl00960
720554010611	RNA polymerase factor sigma-70; Validated; Region: PRK08295
720554010612	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554010613	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
720554010614	DNA binding residues [nucleotide binding]
720554010615	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
720554010616	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
720554010617	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
720554010618	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
720554010619	active site
720554010620	metal binding site [ion binding]; metal-binding site
720554010621	dimerization interface [polypeptide binding]; other site
720554010622	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
720554010623	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
720554010624	active site
720554010625	HIGH motif; other site
720554010626	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
720554010627	KMSKS motif; other site
720554010628	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
720554010629	tRNA binding surface [nucleotide binding]; other site
720554010630	anticodon binding site; other site
720554010631	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
720554010632	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
720554010633	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
720554010634	trimer interface [polypeptide binding]; other site
720554010635	active site
720554010636	substrate binding site [chemical binding]; other site
720554010637	CoA binding site [chemical binding]; other site
720554010638	Membrane protein of unknown function; Region: DUF360; pfam04020
720554010639	8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934
720554010640	8-oxoguanine DNA-glycosylase (ogg); Region: ogg; TIGR00588
720554010641	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
720554010642	minor groove reading motif; other site
720554010643	helix-hairpin-helix signature motif; other site
720554010644	substrate binding pocket [chemical binding]; other site
720554010645	active site
720554010646	Asp23 family; Region: Asp23; cl00574
720554010647	YtxC-like family; Region: YtxC; pfam08812
720554010648	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
720554010649	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
720554010650	metal binding site [ion binding]; metal-binding site
720554010651	dimer interface [polypeptide binding]; other site
720554010652	Domain of unknown function (DUF378); Region: DUF378; pfam04070
720554010653	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
720554010654	hypothetical protein; Validated; Region: PRK00110
720554010655	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554010656	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
720554010657	dimer interface [polypeptide binding]; other site
720554010658	phosphorylation site [posttranslational modification]
720554010659	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554010660	ATP binding site [chemical binding]; other site
720554010661	Mg2+ binding site [ion binding]; other site
720554010662	G-X-G motif; other site
720554010663	CoA binding domain; Region: CoA_binding_2; pfam13380
720554010664	Uncharacterized conserved protein [Function unknown]; Region: COG1739
720554010665	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
720554010666	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
720554010667	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
720554010668	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
720554010669	Catalytic site [active]
720554010670	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
720554010671	active site
720554010672	Ap6A binding site [chemical binding]; other site
720554010673	nudix motif; other site
720554010674	metal binding site [ion binding]; metal-binding site
720554010675	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
720554010676	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
720554010677	HflX GTPase family; Region: HflX; cd01878
720554010678	G1 box; other site
720554010679	GTP/Mg2+ binding site [chemical binding]; other site
720554010680	Switch I region; other site
720554010681	G2 box; other site
720554010682	G3 box; other site
720554010683	Switch II region; other site
720554010684	G4 box; other site
720554010685	G5 box; other site
720554010686	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
720554010687	trimer interface [polypeptide binding]; other site
720554010688	active site
720554010689	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
720554010690	Peptidase family U32; Region: Peptidase_U32; pfam01136
720554010691	Collagenase; Region: DUF3656; pfam12392
720554010692	Peptidase family U32; Region: Peptidase_U32; pfam01136
720554010693	BPG-independent PGAM N-terminus (iPGM_N); Region: iPGM_N; cl17463
720554010694	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: PhosphMutase; cl17294
720554010695	Cell division protein ZapA; Region: ZapA; pfam05164
720554010696	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554010697	Glycosyl hydrolase family 48; Region: Glyco_hydro_48; pfam02011
720554010698	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010699	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010700	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554010701	Cellulose binding domain; Region: CBM_3; smart01067
720554010702	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554010703	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554010704	PspC domain; Region: PspC; pfam04024
720554010705	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; pfam07745
720554010706	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010707	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010708	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
720554010709	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
720554010710	Hemerythrin; Region: Hemerythrin; cd12107
720554010711	Fe binding site [ion binding]; other site
720554010712	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
720554010713	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554010714	S-adenosylmethionine binding site [chemical binding]; other site
720554010715	Domain of unknown function (DUF348); Region: DUF348; pfam03990
720554010716	Domain of unknown function (DUF348); Region: DUF348; pfam03990
720554010717	G5 domain; Region: G5; pfam07501
720554010718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
720554010719	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
720554010720	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
720554010721	active site
720554010722	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
720554010723	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
720554010724	active site
720554010725	HIGH motif; other site
720554010726	KMSKS motif; other site
720554010727	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
720554010728	tRNA binding surface [nucleotide binding]; other site
720554010729	anticodon binding site; other site
720554010730	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
720554010731	dimer interface [polypeptide binding]; other site
720554010732	putative tRNA-binding site [nucleotide binding]; other site
720554010733	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
720554010734	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
720554010735	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
720554010736	Predicted methyltransferases [General function prediction only]; Region: COG0313
720554010737	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
720554010738	putative SAM binding site [chemical binding]; other site
720554010739	putative homodimer interface [polypeptide binding]; other site
720554010740	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
720554010741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554010742	S-adenosylmethionine binding site [chemical binding]; other site
720554010743	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
720554010744	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
720554010745	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
720554010746	DNA polymerase III subunit delta'; Validated; Region: PRK05564
720554010747	DNA polymerase III subunit delta'; Validated; Region: PRK08485
720554010748	Protein of unknown function (DUF327); Region: DUF327; pfam03885
720554010749	thymidylate kinase; Validated; Region: tmk; PRK00698
720554010750	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
720554010751	TMP-binding site; other site
720554010752	ATP-binding site [chemical binding]; other site
720554010753	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
720554010754	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
720554010755	homodimer interface [polypeptide binding]; other site
720554010756	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554010757	catalytic residue [active]
720554010758	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
720554010759	Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600
720554010760	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
720554010761	Putative esterase; Region: Esterase; pfam00756
720554010762	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010763	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554010764	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
720554010765	Beta propeller domain; Region: Beta_propel; pfam09826
720554010766	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
720554010767	nucleotide binding site [chemical binding]; other site
720554010768	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
720554010769	active site
720554010770	Biotin operon repressor [Transcription]; Region: BirA; COG1654
720554010771	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
720554010772	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
720554010773	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
720554010774	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
720554010775	catalytic center binding site [active]
720554010776	ATP binding site [chemical binding]; other site
720554010777	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
720554010778	homooctamer interface [polypeptide binding]; other site
720554010779	active site
720554010780	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
720554010781	dihydropteroate synthase; Region: DHPS; TIGR01496
720554010782	substrate binding pocket [chemical binding]; other site
720554010783	dimer interface [polypeptide binding]; other site
720554010784	inhibitor binding site; inhibition site
720554010785	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
720554010786	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
720554010787	active site
720554010788	metal binding site [ion binding]; metal-binding site
720554010789	homotetramer interface [polypeptide binding]; other site
720554010790	Double zinc ribbon; Region: DZR; pfam12773
720554010791	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
720554010792	1,3-propanediol dehydrogenase-like (PPD); Region: PPD-like; cd08181
720554010793	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
720554010794	dimer interface [polypeptide binding]; other site
720554010795	active site
720554010796	metal binding site [ion binding]; metal-binding site
720554010797	Predicted transcriptional regulators [Transcription]; Region: COG1695
720554010798	Transcriptional regulator PadR-like family; Region: PadR; cl17335
720554010799	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554010800	dimerization interface [polypeptide binding]; other site
720554010801	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
720554010802	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
720554010803	dimer interface [polypeptide binding]; other site
720554010804	putative CheW interface [polypeptide binding]; other site
720554010805	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK14869
720554010806	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
720554010807	DRTGG domain; Region: DRTGG; pfam07085
720554010808	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
720554010809	DHH family; Region: DHH; pfam01368
720554010810	DHHA2 domain; Region: DHHA2; pfam02833
720554010811	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
720554010812	homodecamer interface [polypeptide binding]; other site
720554010813	GTP cyclohydrolase I; Provisional; Region: PLN03044
720554010814	active site
720554010815	putative catalytic site residues [active]
720554010816	zinc binding site [ion binding]; other site
720554010817	GTP-CH-I/GFRP interaction surface; other site
720554010818	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
720554010819	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
720554010820	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
720554010821	TM-ABC transporter signature motif; other site
720554010822	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
720554010823	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
720554010824	Walker A/P-loop; other site
720554010825	ATP binding site [chemical binding]; other site
720554010826	Q-loop/lid; other site
720554010827	ABC transporter signature motif; other site
720554010828	Walker B; other site
720554010829	D-loop; other site
720554010830	H-loop/switch region; other site
720554010831	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
720554010832	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
720554010833	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
720554010834	putative ligand binding site [chemical binding]; other site
720554010835	cyanophycin synthetase; Provisional; Region: PRK14016
720554010836	ATP-grasp domain; Region: ATP-grasp_4; cl17255
720554010837	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
720554010838	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
720554010839	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
720554010840	proposed catalytic triad [active]
720554010841	active site nucleophile [active]
720554010842	isoaspartyl dipeptidase; Provisional; Region: PRK10657
720554010843	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
720554010844	active site
720554010845	SOS regulatory protein LexA; Region: lexA; TIGR00498
720554010846	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
720554010847	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
720554010848	Catalytic site [active]
720554010849	tartrate dehydrogenase; Region: TTC; TIGR02089
720554010850	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
720554010851	Cupin domain; Region: Cupin_2; pfam07883
720554010852	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554010853	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
720554010854	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
720554010855	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
720554010856	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554010857	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
720554010858	DNA binding residues [nucleotide binding]
720554010859	Domain of unknown function (DUF4367); Region: DUF4367; pfam14285
720554010860	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
720554010861	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
720554010862	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
720554010863	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
720554010864	PYR/PP interface [polypeptide binding]; other site
720554010865	dimer interface [polypeptide binding]; other site
720554010866	TPP binding site [chemical binding]; other site
720554010867	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
720554010868	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
720554010869	TPP-binding site [chemical binding]; other site
720554010870	hypothetical protein; Provisional; Region: PRK04164
720554010871	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
720554010872	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
720554010873	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
720554010874	ykoK leader
720554010875	FlgN protein; Region: FlgN; pfam05130
720554010876	Flagellar protein FliS; Region: FliS; cl00654
720554010877	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
720554010878	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
720554010879	FlaG protein; Region: FlaG; pfam03646
720554010880	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
720554010881	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554010882	NAD(P) binding site [chemical binding]; other site
720554010883	active site
720554010884	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
720554010885	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
720554010886	inhibitor-cofactor binding pocket; inhibition site
720554010887	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554010888	catalytic residue [active]
720554010889	pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590
720554010890	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
720554010891	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
720554010892	Formyl transferase catalytic core domain found in a group of proteins with unknown functions; Region: FMT_core_like_1; cd08821
720554010893	putative active site [active]
720554010894	putative substrate binding site [chemical binding]; other site
720554010895	putative cosubstrate binding site; other site
720554010896	catalytic site [active]
720554010897	pseudaminic acid synthase; Region: PseI; TIGR03586
720554010898	NeuB family; Region: NeuB; pfam03102
720554010899	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
720554010900	NeuB binding interface [polypeptide binding]; other site
720554010901	putative substrate binding site [chemical binding]; other site
720554010902	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
720554010903	Acid Phosphatase; Region: Acid_PPase; cl17256
720554010904	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
720554010905	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
720554010906	SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat; Region: GT2_SpsF; cd02518
720554010907	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554010908	S-adenosylmethionine binding site [chemical binding]; other site
720554010909	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
720554010910	Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719
720554010911	NAD(P) binding site [chemical binding]; other site
720554010912	homodimer interface [polypeptide binding]; other site
720554010913	substrate binding site [chemical binding]; other site
720554010914	active site
720554010915	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
720554010916	Protein of unknown function DUF115; Region: MAF_flag10; pfam01973
720554010917	flagellin; Provisional; Region: PRK12804
720554010918	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
720554010919	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
720554010920	flagellin; Provisional; Region: PRK12804
720554010921	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
720554010922	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
720554010923	flagellin; Provisional; Region: PRK12804
720554010924	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
720554010925	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
720554010926	carbon storage regulator; Provisional; Region: PRK01712
720554010927	flagellar assembly protein FliW; Provisional; Region: PRK13285
720554010928	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701
720554010929	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
720554010930	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
720554010931	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
720554010932	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
720554010933	flagellar hook-associated protein FlgK; Region: flgK_ends; TIGR02492
720554010934	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
720554010935	metal ion-dependent adhesion site (MIDAS); other site
720554010936	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
720554010937	FlgN protein; Region: FlgN; pfam05130
720554010938	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
720554010939	flagellar operon protein TIGR03826; Region: YvyF
720554010940	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
720554010941	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
720554010942	active site
720554010943	Mechanosensitive ion channel; Region: MS_channel; pfam00924
720554010944	cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223
720554010945	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
720554010946	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
720554010947	catalytic triad [active]
720554010948	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
720554010949	anti sigma factor interaction site; other site
720554010950	regulatory phosphorylation site [posttranslational modification]; other site
720554010951	Rubredoxin [Energy production and conversion]; Region: COG1773
720554010952	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
720554010953	iron binding site [ion binding]; other site
720554010954	Transposase IS200 like; Region: Y1_Tnp; pfam01797
720554010955	Protein of unknown function (DUF1256); Region: DUF1256; cl06087
720554010956	PAS fold; Region: PAS_4; pfam08448
720554010957	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
720554010958	putative active site [active]
720554010959	heme pocket [chemical binding]; other site
720554010960	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
720554010961	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
720554010962	Putative amidase domain; Region: Amidase_6; pfam12671
720554010963	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
720554010964	transcription termination factor Rho; Provisional; Region: PRK12678
720554010965	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
720554010966	CBF/Mak21 family; Region: CBF; cl10505
720554010967	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
720554010968	RNA binding site [nucleotide binding]; other site
720554010969	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
720554010970	multimer interface [polypeptide binding]; other site
720554010971	Walker A motif; other site
720554010972	ATP binding site [chemical binding]; other site
720554010973	Walker B motif; other site
720554010974	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
720554010975	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
720554010976	Walker A/P-loop; other site
720554010977	ATP binding site [chemical binding]; other site
720554010978	Q-loop/lid; other site
720554010979	ABC transporter signature motif; other site
720554010980	Walker B; other site
720554010981	D-loop; other site
720554010982	H-loop/switch region; other site
720554010983	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
720554010984	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
720554010985	ABC-ATPase subunit  interface; other site
720554010986	dimer interface [polypeptide binding]; other site
720554010987	putative PBP binding regions; other site
720554010988	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
720554010989	Periplasmic binding protein YvrC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143
720554010990	putative binding site residues; other site
720554010991	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554010992	Fn3 associated; Region: Fn3_assoc; pfam13287
720554010993	CotH protein; Region: CotH; pfam08757
720554010994	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
720554010995	Ligand Binding Site [chemical binding]; other site
720554010996	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
720554010997	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
720554010998	active site
720554010999	tetramer interface; other site
720554011000	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
720554011001	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
720554011002	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
720554011003	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
720554011004	dimer interface [polypeptide binding]; other site
720554011005	ssDNA binding site [nucleotide binding]; other site
720554011006	tetramer (dimer of dimers) interface [polypeptide binding]; other site
720554011007	Ribosomal protein S6; Region: Ribosomal_S6; pfam01250
720554011008	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
720554011009	GAF domain; Region: GAF_2; pfam13185
720554011010	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
720554011011	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
720554011012	metal binding site [ion binding]; metal-binding site
720554011013	active site
720554011014	I-site; other site
720554011015	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
720554011016	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
720554011017	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
720554011018	Domain of unknown function (DUF368); Region: DUF368; pfam04018
720554011019	putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional; Region: PRK12344
720554011020	Desulfobacterium autotrophicum LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA3; cd07941
720554011021	active site
720554011022	catalytic residues [active]
720554011023	metal binding site [ion binding]; metal-binding site
720554011024	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
720554011025	2-isopropylmalate synthase; Validated; Region: PRK00915
720554011026	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
720554011027	active site
720554011028	catalytic residues [active]
720554011029	metal binding site [ion binding]; metal-binding site
720554011030	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
720554011031	ketol-acid reductoisomerase; Provisional; Region: PRK05479
720554011032	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
720554011033	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
720554011034	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
720554011035	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
720554011036	putative valine binding site [chemical binding]; other site
720554011037	dimer interface [polypeptide binding]; other site
720554011038	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
720554011039	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK06048
720554011040	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
720554011041	PYR/PP interface [polypeptide binding]; other site
720554011042	dimer interface [polypeptide binding]; other site
720554011043	TPP binding site [chemical binding]; other site
720554011044	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
720554011045	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
720554011046	TPP-binding site [chemical binding]; other site
720554011047	dimer interface [polypeptide binding]; other site
720554011048	Predicted integral membrane protein [Function unknown]; Region: COG5542
720554011049	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
720554011050	nucleoside/Zn binding site; other site
720554011051	dimer interface [polypeptide binding]; other site
720554011052	catalytic motif [active]
720554011053	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
720554011054	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
720554011055	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
720554011056	protein binding site [polypeptide binding]; other site
720554011057	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
720554011058	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
720554011059	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
720554011060	Peptidase M14 carboxypeptidase family-like domain of Endopeptidase I; Region: M14_Endopeptidase_I; cd06229
720554011061	putative active site [active]
720554011062	Zn binding site [ion binding]; other site
720554011063	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
720554011064	non-specific DNA binding site [nucleotide binding]; other site
720554011065	salt bridge; other site
720554011066	sequence-specific DNA binding site [nucleotide binding]; other site
720554011067	DNA topoisomerase III; Provisional; Region: PRK07726
720554011068	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
720554011069	active site
720554011070	putative interdomain interaction site [polypeptide binding]; other site
720554011071	putative metal-binding site [ion binding]; other site
720554011072	putative nucleotide binding site [chemical binding]; other site
720554011073	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
720554011074	domain I; other site
720554011075	DNA binding groove [nucleotide binding]
720554011076	phosphate binding site [ion binding]; other site
720554011077	domain II; other site
720554011078	domain III; other site
720554011079	nucleotide binding site [chemical binding]; other site
720554011080	catalytic site [active]
720554011081	domain IV; other site
720554011082	YabG peptidase U57; Region: Peptidase_U57; cl05250
720554011083	Acyltransferase family; Region: Acyl_transf_3; pfam01757
720554011084	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
720554011085	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
720554011086	Protein of unknown function DUF58; Region: DUF58; pfam01882
720554011087	MoxR-like ATPases [General function prediction only]; Region: COG0714
720554011088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
720554011089	Walker A motif; other site
720554011090	ATP binding site [chemical binding]; other site
720554011091	Walker B motif; other site
720554011092	arginine finger; other site
720554011093	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011094	dockerin binding interface; other site
720554011095	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011096	dockerin binding interface; other site
720554011097	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011098	dockerin binding interface; other site
720554011099	Cellulose binding domain; Region: CBM_2; pfam00553
720554011100	Cellulose binding domain; Region: CBM_2; pfam00553
720554011101	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
720554011102	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
720554011103	DDE superfamily endonuclease; Region: DDE_5; cl17874
720554011104	Dockerin type I repeat; Region: Dockerin_1; pfam00404
720554011105	Carbohydrate Binding Module family 35 (CBM35), pectate lyase-like; appended mainly to enzymes that bind mannan (Man), xylan, glucuronic acid (GlcA) and possibly glucans; Region: CBM35_pectate_lyase-like; cd04082
720554011106	Ca binding site [ion binding]; other site
720554011107	Ca binding site (active) [ion binding]; other site
720554011108	ligand binding site [chemical binding]; other site
720554011109	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
720554011110	metal binding site [ion binding]; metal-binding site
720554011111	active site
720554011112	RDD family; Region: RDD; pfam06271
720554011113	RDD family; Region: RDD; pfam06271
720554011114	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
720554011115	Transcriptional regulators [Transcription]; Region: PurR; COG1609
720554011116	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
720554011117	DNA binding site [nucleotide binding]
720554011118	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_1; cd06277
720554011119	putative ligand binding site [chemical binding]; other site
720554011120	putative dimerization interface [polypeptide binding]; other site
720554011121	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
720554011122	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
720554011123	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
720554011124	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
720554011125	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
720554011126	hinge; other site
720554011127	active site
720554011128	YycH protein; Region: YycI; cl02015
720554011129	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
720554011130	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
720554011131	dimerization interface [polypeptide binding]; other site
720554011132	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
720554011133	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
720554011134	dimer interface [polypeptide binding]; other site
720554011135	phosphorylation site [posttranslational modification]
720554011136	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
720554011137	ATP binding site [chemical binding]; other site
720554011138	Mg2+ binding site [ion binding]; other site
720554011139	G-X-G motif; other site
720554011140	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
720554011141	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
720554011142	active site
720554011143	phosphorylation site [posttranslational modification]
720554011144	intermolecular recognition site; other site
720554011145	dimerization interface [polypeptide binding]; other site
720554011146	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
720554011147	DNA binding site [nucleotide binding]
720554011148	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
720554011149	ligand binding site; other site
720554011150	tetramer interface; other site
720554011151	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
720554011152	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
720554011153	active site
720554011154	homodimer interface [polypeptide binding]; other site
720554011155	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
720554011156	NeuB family; Region: NeuB; pfam03102
720554011157	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
720554011158	NeuB binding interface [polypeptide binding]; other site
720554011159	putative substrate binding site [chemical binding]; other site
720554011160	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
720554011161	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
720554011162	putative trimer interface [polypeptide binding]; other site
720554011163	putative CoA binding site [chemical binding]; other site
720554011164	FOG: CBS domain [General function prediction only]; Region: COG0517
720554011165	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain associated with the NTP (Nucleotidyl transferase) domain downstream. CBS is a small domain originally identified in cystathionine beta-synthase and subsequently...; Region: CBS_pair_NTP_transferase_assoc; cd04607
720554011166	NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_2; cd06426
720554011167	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
720554011168	Substrate binding site; other site
720554011169	metal-binding site
720554011170	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
720554011171	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
720554011172	inhibitor-cofactor binding pocket; inhibition site
720554011173	pyridoxal 5'-phosphate binding site [chemical binding]; other site
720554011174	catalytic residue [active]
720554011175	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
720554011176	NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family; Region: EDH_00030; TIGR04180
720554011177	NAD binding site [chemical binding]; other site
720554011178	substrate binding site [chemical binding]; other site
720554011179	active site
720554011180	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
720554011181	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
720554011182	NAD(P) binding site [chemical binding]; other site
720554011183	homodimer interface [polypeptide binding]; other site
720554011184	substrate binding site [chemical binding]; other site
720554011185	active site
720554011186	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
720554011187	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
720554011188	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
720554011189	Transposase; Region: DEDD_Tnp_IS110; pfam01548
720554011190	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
720554011191	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
720554011192	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
720554011193	NAD binding site [chemical binding]; other site
720554011194	substrate binding site [chemical binding]; other site
720554011195	homodimer interface [polypeptide binding]; other site
720554011196	active site
720554011197	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
720554011198	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
720554011199	Probable Catalytic site; other site
720554011200	Protein of unknown function DUF70; Region: DUF70; cl00785
720554011201	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
720554011202	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
720554011203	active site
720554011204	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
720554011205	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554011206	NAD(P) binding site [chemical binding]; other site
720554011207	active site
720554011208	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
720554011209	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
720554011210	NAD(P) binding site [chemical binding]; other site
720554011211	active site
720554011212	Bacterial sugar transferase; Region: Bac_transf; pfam02397
720554011213	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
720554011214	binding surface
720554011215	TPR motif; other site
720554011216	Tetratricopeptide repeat; Region: TPR_12; pfam13424
720554011217	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
720554011218	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
720554011219	Chain length determinant protein; Region: Wzz; pfam02706
720554011220	basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins; Region: B_zip1; cl02576
720554011221	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
720554011222	S-layer homology domain; Region: SLH; pfam00395
720554011223	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
720554011224	Bacterial Ig-like domain; Region: Big_5; pfam13205
720554011225	S-layer homology domain; Region: SLH; pfam00395
720554011226	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
720554011227	Bacterial Ig-like domain; Region: Big_5; pfam13205
720554011228	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
720554011229	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
720554011230	FOG: CBS domain [General function prediction only]; Region: COG0517
720554011231	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622
720554011232	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
720554011233	PGAP1-like protein; Region: PGAP1; pfam07819
720554011234	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
720554011235	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
720554011236	putative active site [active]
720554011237	putative NTP binding site [chemical binding]; other site
720554011238	putative nucleic acid binding site [nucleotide binding]; other site
720554011239	Domains similar to the eukaryotic reeler domain and bacterial cohesins; Region: Reeler_cohesin_like; cl14606
720554011240	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011241	dockerin binding interface; other site
720554011242	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011243	dockerin binding interface; other site
720554011244	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011245	dockerin binding interface; other site
720554011246	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011247	dockerin binding interface; other site
720554011248	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011249	dockerin binding interface; other site
720554011250	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011251	dockerin binding interface; other site
720554011252	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011253	dockerin binding interface; other site
720554011254	Cellulose binding domain; Region: CBM_2; pfam00553
720554011255	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011256	dockerin binding interface; other site
720554011257	Cellulose binding domain; Region: CBM_2; pfam00553
720554011258	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011259	dockerin binding interface; other site
720554011260	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011261	dockerin binding interface; other site
720554011262	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011263	dockerin binding interface; other site
720554011264	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011265	dockerin binding interface; other site
720554011266	Type I cohesin domain, interaction partner of dockerin; Region: Type_I_cohesin_like; cd08548
720554011267	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
720554011268	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
720554011269	dimerization interface [polypeptide binding]; other site
720554011270	active site
720554011271	L-aspartate oxidase; Provisional; Region: PRK06175
720554011272	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
720554011273	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
720554011274	Quinolinate synthetase A protein; Region: NadA; pfam02445
720554011275	Accessory gene regulator B; Region: AgrB; pfam04647
720554011276	DNA gyrase subunit A; Validated; Region: PRK05560
720554011277	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
720554011278	CAP-like domain; other site
720554011279	active site
720554011280	primary dimer interface [polypeptide binding]; other site
720554011281	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
720554011282	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
720554011283	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
720554011284	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
720554011285	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
720554011286	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
720554011287	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
720554011288	ParB-like nuclease domain; Region: ParBc; pfam02195
720554011289	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
720554011290	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
720554011291	S-adenosylmethionine binding site [chemical binding]; other site
720554011292	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
720554011293	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
720554011294	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
720554011295	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
720554011296	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
720554011297	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
720554011298	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
720554011299	GTP/Mg2+ binding site [chemical binding]; other site
720554011300	G4 box; other site
720554011301	trmE is a tRNA modification GTPase; Region: trmE; cd04164
720554011302	G1 box; other site
720554011303	G1 box; other site
720554011304	GTP/Mg2+ binding site [chemical binding]; other site
720554011305	Switch I region; other site
720554011306	Switch I region; other site
720554011307	G2 box; other site
720554011308	G2 box; other site
720554011309	Switch II region; other site
720554011310	G3 box; other site
720554011311	G3 box; other site
720554011312	Switch II region; other site
720554011313	G4 box; other site
720554011314	G5 box; other site
720554011315	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
720554011316	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
720554011317	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
720554011318	G-X-X-G motif; other site
720554011319	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
720554011320	RxxxH motif; other site
720554011321	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
720554011322	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
720554011323	Haemolytic domain; Region: Haemolytic; pfam01809
720554011324	ribonuclease P; Reviewed; Region: rnpA; PRK00499
720554011325	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399