-- dump date   	20140619_044445
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001219835.1	3'-5' exonuclease of DNA polymerase III
YP_001219870.1	contains predicted intein
YP_001393436.1	chromosomal replication initiator protein; binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself
YP_001393437.1	DNA polymerase III, beta chain; binds the polymerase to DNA and acts as a sliding clamp
YP_001393439.1	DNA replication and repair protein RecF; Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_001393441.1	DNA gyrase, subunit B; negatively supercoils closed circular double-stranded DNA
YP_001393442.1	DNA gyrase, subunit A; negatively supercoils closed circular double-stranded DNA
YP_001393448.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001393450.1	regulatory protein VanR
YP_001393451.1	sensor protein VanS
YP_001393463.1	ATPase component
YP_001393467.1	related to phosphoesterase
YP_001393471.1	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate
YP_001393476.1	predicted phosphatidylserine decarboxylase; catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_001393480.1	predicted tRNA-specific adenosine deaminase
YP_001393485.1	flavoredoxin
YP_001393491.1	predicted phosphoenolpyruvate synthase
YP_001393497.1	ATPase and permease component
YP_001393498.1	ATPase and permease component
YP_001393510.1	predicted aspartyl aminopeptidase; catalyzes the removal of amino acids from the N termini of peptides
YP_001393512.1	adenylosuccinate synthase; catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_001393516.1	acts to load the DnaB helicase onto the initiation site during DNA replication
YP_001393520.1	3-oxoacyl-[acyl-carrier-protein] synthase
YP_001393521.1	acyl carrier protein
YP_001393522.1	predicted enoyl-[acyl-carrier protein] reductase
YP_001393523.1	malonyl-CoA-acyl carrier protein transacylase
YP_001393524.1	3-oxoacyl-[acyl-carrier-protein] reductase
YP_001393525.1	3-oxoacyl-[acyl-carrier-protein] synthase; FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_001393526.1	biotin carboxyl carrier protein of acetyl-CoA carboxylase
YP_001393527.1	predicted hydroxymyristoyl-[acyl carrier protein] dehydratase; in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_001393529.1	acetyl-coenzyme A carboxylase, subunit beta
YP_001393530.1	acetyl-coenzyme A carboxylase, subunit alpha; catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_001393531.1	ferritin
YP_001393536.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001393537.1	methylated-DNA--protein-cysteine methyltransferase
YP_001393541.1	partial similarity to the SecA translocase subunit
YP_001393545.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001393548.1	predicted glutamine synthetase
YP_001393549.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_001393556.1	predicted 2-phosphosulfolactate phosphatase; catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate
YP_001393561.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001393563.1	stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus
YP_001393564.1	predicted bifunctional protein GcaD; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_001393565.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_001393569.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_001393570.1	predicted transcription-repair coupling factor
YP_001393571.1	predicted foldase protein precursor; cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein
YP_001393575.1	DNA-binding protein HU
YP_001393582.1	tRNA(Ile)-lysidine synthase
YP_001393583.1	hypoxanthine-guanine phosphoribosyltransferase
YP_001393584.1	cell division protein FtsH homolog
YP_001393586.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_001393587.1	tRNA-dihydrouridine synthase
YP_001393589.1	transcription elongation factor; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_001393590.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001393591.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001393592.1	predicted UDP-N-acetylmuramoylalanine--D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_001393593.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001393595.1	predicted alpha-ribazole phosphatase
YP_001393599.1	predicted ATP-dependent Clp protease, ATP-binding subunit
YP_001393600.1	DNA repair protein RadA homolog; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001393601.1	non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair
YP_001393604.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_001393605.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_001393609.1	predicted RNA polymerase sigma factor; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_001393610.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001393611.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif
YP_001393612.1	predicted preprotein translocase SecE subunit
YP_001393613.1	Modulates Rho-dependent transcription termination
YP_001393614.1	binds directly to 23S ribosomal RNA
YP_001393615.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001393616.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001393617.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001393618.1	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_001393619.1	DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_001393621.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001393622.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001393623.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001393624.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001393625.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_001393626.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001393627.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001393628.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001393629.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001393630.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_001393631.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_001393632.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_001393633.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001393634.1	one of the stabilizing components for the large ribosomal subunit
YP_001393635.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_001393636.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_001393637.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_001393638.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001393639.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
YP_001393640.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001393641.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_001393642.1	binds 5S rRNA along with protein L5 and L25
YP_001393643.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001393644.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_001393645.1	late assembly protein
YP_001393646.1	preprotein translocase, SecY subunit; forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_001393647.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_001393648.1	predicted methionine aminopeptidase
YP_001393649.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_001393650.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_001393651.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_001393652.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001393653.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_001393654.1	DNA-directed RNA polymerase alpha chain; catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001393655.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_001393656.1	with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene
YP_001393657.1	with CbiNQ forms the ABC transporter for cobalt import; Clostridia have two adjacent copies of this gene
YP_001393659.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001393660.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_001393661.1	forms a direct contact with the tRNA during translation
YP_001393666.1	related to rpoE
YP_001393704.1	methylaspartate mutase, subunit E
YP_001393705.1	fumarate hydratase, alpha subunit; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid
YP_001393706.1	fumarate hydratase, beta subunit
YP_001393709.1	phosphoenolpyruvate-protein phosphotransferase
YP_001393712.1	thioredoxin
YP_001393713.1	predicted thioredoxin reductase
YP_001393718.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_001393719.1	glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001393728.1	pyrroline-5-carboxylate reductase
YP_001393736.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_001393738.1	predicted spore germination protein GerKB
YP_001393740.1	predicted spore germination protein GerKC
YP_001393741.1	predicted spore germination protein GerKA
YP_001393743.1	ferric uptake regulation protein
YP_001393745.1	peptide methionine sulfoxide reductase; this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
YP_001393755.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_001393761.1	predicted peptide deformylase
YP_001393764.1	alkyl hydroperoxide reductase, subunit F
YP_001393765.1	alkyl hydroperoxide reductase, subunit C
YP_001393772.1	nitrogenase iron-iron protein alpha chain
YP_001393773.1	nitrogenase iron-iron protein delta chain
YP_001393774.1	nitrogenase iron-iron protein beta chain
YP_001393796.1	predicted poly(beta-D-mannuronate) O-acetylase
YP_001393821.1	predicted Cu-Zn superoxide dismutase
YP_001393828.1	predicted threonine dehydratase; catalyzes the formation of 2-oxobutanoate from L-threonine
YP_001393829.1	related to Mrp-family
YP_001393838.1	phosphoglycerate dehydrogenase
YP_001393842.1	formate-tetrahydrofolate ligase; catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate
YP_001393843.1	methenyltetrahydrofolate cyclohydrolase
YP_001393844.1	bifunctional protein FolD
YP_001393848.1	predicted O-sialoglycoprotein endopeptidase; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_001393849.1	predicted pyruvate carboxylase; biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
YP_001393855.1	modulates transcription in response to the NADH/NAD(+) redox state
YP_001393856.1	catalyzes the formation of crotonoyl-CoA from (3R)-3-hydroxybutanoyl-CoA
YP_001393857.1	butyryl-CoA dehydrogenase
YP_001393858.1	electron transfer flavoprotein beta subunit
YP_001393859.1	electron transfer flavoprotein alpha subunit
YP_001393860.1	3-hydroxybutyryl-CoA dehydrogenase
YP_001393862.1	function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain
YP_001393865.1	10 kDa chaperonin; 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_001393866.1	60 kDa chaperonin; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001393867.1	inosine-5'-monophosphate dehydrogenase; catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_001393868.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_001393910.1	Na(+)/H(+) antiporter
YP_001393911.1	catalyzes the formation of pyruvate from D-cysteine
YP_001393914.1	predicted chaperone protein
YP_001393915.1	predicted chaperone protein
YP_001393916.1	predicted chaperone protein
YP_001393917.1	predicted chaperone protein
YP_001393940.1	predicted protein-glutamine gamma-glutamyltransferase; involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links
YP_001393944.1	signal-transduction and transcriptional-control protein
YP_001393945.1	NADPH-dependent butanol dehydrogenase
YP_001393948.1	Converts isocitrate to alpha ketoglutarate
YP_001393961.1	predicted DNA topoisomerase I
YP_001393975.1	chemotaxis-specific methylesterase
YP_001394004.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_001394005.1	cell division protein ftsH homolog
YP_001394007.1	hydrogenase maturation protein HydE; catalyzes the formation of biotin from dethiobiotin and sulfur
YP_001394009.1	aspartokinase
YP_001394010.1	diaminopimelate decarboxylase
YP_001394011.1	cyclic beta 1-2 glucan synthetase
YP_001394012.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001394026.1	related to Mrp-family
YP_001394032.1	predicted ferric uptake regulator
YP_001394039.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_001394040.1	pantoate-beta-alanine ligase; catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_001394042.1	stage V sporulation protein R
YP_001394051.1	carbamoyl-phosphate synthase small chain; catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_001394052.1	carbamoyl-phosphate synthase large chain; four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_001394053.1	N-acyl-L-amino acid amidohydrolase
YP_001394059.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_001394060.1	glutamate-1-semialdehyde 2,1-aminomutase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_001394062.1	alanine dehydrogenase
YP_001394071.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_001394072.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_001394077.1	predicted spore coat protein CotJC
YP_001394078.1	predicted spore coat protein CotJB
YP_001394100.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001394101.1	L-serine dehydratase, beta chain
YP_001394102.1	L-serine dehydratase, alpha chain
YP_001394103.1	cold shock protein
YP_001394105.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_001394114.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_001394115.1	predicted threonine-phosphate decarboxylase
YP_001394116.1	cob(I)yrinic acid a,c-diamide adenosyltransferase
YP_001394117.1	catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3
YP_001394119.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_001394120.1	porphyrin biosynthesis protein HemD
YP_001394121.1	sirohydrochlorin cobaltochelatase
YP_001394122.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_001394123.1	cobyrinic acid A,C-diamide synthase; responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
YP_001394124.1	catalyzes the interconversion of precorrin-8X and cobyrinic acid
YP_001394125.1	precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A
YP_001394126.1	precorrin-6Y C(5)-methyltransferase
YP_001394127.1	precorrin-6Y C(15)-methyltransferase
YP_001394128.1	precorrin-2 C(20)-methyltransferase; catalyzes the formation of precorrin-3A from precorrin-2
YP_001394129.1	precorrin-4 C(11)-methyltransferase
YP_001394130.1	precorrin-6A reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6
YP_001394131.1	precorrin-3B C(17)-methyltransferase
YP_001394132.1	bifunctional adenosylcobalamin biosynthesis protein CobU; catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP
YP_001394133.1	alpha-ribazole phosphatase
YP_001394137.1	NADPH-dependent butanol dehydrogenase
YP_001394149.1	quinolinate synthetase A
YP_001394150.1	L-aspartate oxidase
YP_001394151.1	nicotinate-nucleotide pyrophosphorylase
YP_001394153.1	peptide chain release factor 3
YP_001394159.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_001394178.1	predicted glycine betaine/L-proline transporter, ATP-binding protein
YP_001394179.1	predicted glycine betaine/L-proline transporter, permease protein
YP_001394180.1	predicted glycine betaine/L-proline binding protein
YP_001394181.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001394185.1	phospho-2-dehydro-3-deoxyheptonate aldolase; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate
YP_001394186.1	prephenate dehydrogenase
YP_001394187.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_001394188.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_001394189.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_001394190.1	predicted bifunctional chorismate mutase/ prephenate dehydratase
YP_001394191.1	shikimate dehydrogenase
YP_001394192.1	shikimate kinase
YP_001394197.1	predicted copper-transporting ATPase
YP_001394199.1	predicted phosphoglucomutase
YP_001394200.1	fructose-1,6-bisphosphatase
YP_001394201.1	predicted cardiolipin synthetase
YP_001394217.1	cysteine desulfurase
YP_001394218.1	thiamine biosynthesis protein; Required for the synthesis of the thiazole moiety
YP_001394226.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001394227.1	nitrogenase molybdenum-iron protein, beta chain
YP_001394232.1	predicted cysteine desulfurase
YP_001394233.1	NifU-like protein
YP_001394234.1	predicted adenosine deaminase; catalyzes the formation of inosine from adenosine
YP_001394242.1	glycerol dehydratase, large subunit
YP_001394243.1	glycerol dehydratase, small subunit
YP_001394257.1	predicted phenylalanine biosynthesis protein
YP_001394258.1	homoserine dehydrogenase
YP_001394259.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_001394263.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_001394264.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_001394265.1	functions in MreBCD complex in some organisms
YP_001394266.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_001394269.1	septum site-determining protein MinC; blocks the formation of polar Z-ring septums
YP_001394270.1	septum site-determining protein MinD
YP_001394271.1	septum formation topological specificity factor
YP_001394277.1	predicted ribonuclease E
YP_001394280.1	involved in the peptidyltransferase reaction during translation
YP_001394281.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_001394282.1	predicted nicotinate-nucleotide adenylyltransferase; transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_001394285.1	predicted ribosomal large subunit pseudouridine synthase D
YP_001394286.1	predicted D-alanyl-D-alanine carboxypeptidase precursor
YP_001394288.1	predicted aspartate aminotransferase; catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001394291.1	predicted membrane protein
YP_001394292.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_001394293.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001394294.1	predicted germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YP_001394297.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001394298.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001394299.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_001394300.1	heat shock protein; with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_001394301.1	chaperone protein; heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001394302.1	chaperone protein; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_001394303.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_001394304.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_001394307.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_001394314.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_001394315.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_001394316.1	predicted DNA repair protein; involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_001394319.1	pyruvate, phosphate dikinase; catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_001394321.1	predicted glyoxylate reductase
YP_001394323.1	predicted glutamate 5-kinase
YP_001394334.1	catalyzes the reduction of hydroxylamine to ammonia and water
YP_001394336.1	predicted dethiobiotin synthetase; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_001394337.1	adenosylmethionine-8-amino-7-oxononanoate aminotransferase
YP_001394338.1	predicted spore coat protein
YP_001394339.1	dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate
YP_001394340.1	synthesizes RNA primers at the replication forks
YP_001394341.1	RNA polymerase sigma factor
YP_001394347.1	ferrous iron transport protein B
YP_001394348.1	ferrous iron transport protein A
YP_001394351.1	dihydropteroate synthase
YP_001394352.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_001394364.1	Catalyzes the conversion of citrate to isocitrate
YP_001394366.1	predicted methionine synthase
YP_001394371.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_001394372.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_001394382.1	glutamine-dependent NAD(+) synthetase; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_001394386.1	predicted ATP-dependent nuclease, subunit B
YP_001394387.1	5'-nucleotidase SurE; catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_001394388.1	predicted transaldolase
YP_001394390.1	RNA polymerase sigma-E factor; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_001394392.1	cystathione gamma-synthase
YP_001394393.1	cysteine synthase
YP_001394397.1	3-dehydroquinate dehydratase
YP_001394398.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_001394404.1	predicted shikimate 5-dehydrogenase; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_001394409.1	predicted spore coat polysaccharide biosynthesis protein
YP_001394412.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001394414.1	predicted asparagine synthetase
YP_001394423.1	nitrogenase iron protein
YP_001394424.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001394425.1	nitrogenase molybdenum-iron protein, beta chain
YP_001394426.1	FeMo cofactor biosynthesis protein NifB
YP_001394432.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001394433.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001394434.1	nitrogenase molybdenum-iron protein, beta chain
YP_001394435.1	nitrogenase iron protein
YP_001394436.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001394437.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001394438.1	nitrogenase molybdenum-iron protein, beta chain
YP_001394439.1	oligopeptide ABC transporter, extracellular solute-binding protein
YP_001394440.1	oligopeptide ABC transporter, permease protein
YP_001394441.1	oligopeptide ABC transporter, permease protein
YP_001394442.1	oligopeptide ABC transporter, ATP-binding protein
YP_001394443.1	oligopeptide ABC transporter, ATP-binding protein
YP_001394454.1	predicted spore germination protein XA
YP_001394458.1	predicted DNA topoisomerase III; decatenates replicating daughter chromosomes
YP_001394459.1	NAD-dependent butanol dehydrogenase
YP_001394462.1	related to EutM
YP_001394463.1	related to EutL
YP_001394470.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_001394471.1	predicted acetolactate synthase, large subunit
YP_001394477.1	predicted cysteine desulfurase
YP_001394478.1	predicted tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_001394479.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_001394495.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_001394496.1	pyruvate formate-lyase activating enzyme
YP_001394497.1	pyruvate formate-lyase
YP_001394503.1	predicted general secretion pathway protein E
YP_001394504.1	predicted general secretion pathway protein F
YP_001394512.1	chemotaxis protein CheY
YP_001394513.1	chemotaxis protein CheA
YP_001394514.1	chemotaxis protein CheW
YP_001394534.1	predicted deoxyuridine 5'-triphosphate nucleotidohydrolase; catalyzes the formation of dUMP from dUTP
YP_001394536.1	predicted lactoylglutathione lyase
YP_001394537.1	single-stranded DNA-binding protein
YP_001394539.1	flagellin subunit protein B
YP_001394540.1	flagellar basal body protein FlgB; with FlgF and C makes up the proximal portion of the flagellar basal body rod
YP_001394541.1	flagellar basal-body rod protein FlgC; with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_001394542.1	flagellar hook-basal body complex protein FliE; forms a junction between the M-ring and FlgB during flagella biosynthesis
YP_001394543.1	flagellar M-ring protein FliF; the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_001394544.1	flagellar motor switch protein FliG; One of three proteins involved in switching the direction of the flagellar rotation
YP_001394545.1	flagellar assembly protein FliH
YP_001394546.1	flagellum-specific ATP synthase
YP_001394547.1	flagellar biosynthesis chaperone FliJ
YP_001394549.1	predicted flagellar hook protein FlgD
YP_001394550.1	flagellar hook protein FlgE
YP_001394552.1	flagellar biosynthesis protein FliL
YP_001394553.1	flagellar biosynthesis protein FliO
YP_001394554.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_001394555.1	flagellar biosynthesis protein FliQ
YP_001394556.1	FlhB is a membrane protein responsible for substrate specificity in switching from rod/hook-type export to filament-type export; FliR is required for export of flagellar proteins, although a specific role has not yet been determined
YP_001394557.1	membrane protein involved in the flagellar export apparatus
YP_001394558.1	flagellar biosynthesis protein FlhF; positive regulator of class III flagellar genes
YP_001394559.1	flagellar synthesis regulator FleN
YP_001394562.1	flagellar basal-body rod protein; makes up the distal portion of the flagellar basal body rod; the Clostridia have two adjacent copies of the FlgG gene
YP_001394563.1	flagellar basal-body rod protein; makes up the distal portion of the flagellar basal body rod; the Clostridia have 2 adjacent copies of the FlgG gene
YP_001394566.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_001394570.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_001394571.1	predicted S-adenosyl-methyltransferase
YP_001394573.1	predicted cell division protein
YP_001394574.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_001394575.1	predicted UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
YP_001394576.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001394577.1	cell division protein
YP_001394578.1	cell division protein
YP_001394587.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_001394588.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_001394590.1	predicted uracil permease
YP_001394591.1	predicted bifunctional protein PyrR; regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_001394593.1	predicted diaminopimelate epimerase; involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_001394595.1	predicted general secretion pathway protein E
YP_001394596.1	predicted general secretion pathway protein F
YP_001394605.1	predicted Xaa-Pro dipeptidase
YP_001394606.1	elongation factor EF-P; Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_001394609.1	necessary for complete engulfment of forespore
YP_001394617.1	N utilization substance protein B homolog; Regulates rRNA biosynthesis by transcriptional antitermination
YP_001394618.1	predicted exodeoxyribonuclease VII large subunit; bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_001394619.1	predicted exodeoxyribonuclease VII small subunit
YP_001394620.1	predicted geranyltranstransferase
YP_001394621.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_001394623.1	nicotinamide adenine dinucleotide kinase
YP_001394624.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
YP_001394625.1	predicted DNA repair protein RecN
YP_001394627.1	stage 0 sporulation protein A homolog
YP_001394629.1	predicted stage II sporulation protein M
YP_001394631.1	predicted tyrosine recombinase
YP_001394632.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_001394643.1	predicted D-alanyl-D-alanine carboxypeptidase precursor
YP_001394644.1	predicted bifunctional tRNA-nucleotidyltransferase
YP_001394645.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB
YP_001394646.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer
YP_001394654.1	electron transport complex protein RnfC
YP_001394655.1	electron transport complex protein RnfD
YP_001394656.1	electron transport complex protein RnfG
YP_001394657.1	electron transport complex protein RnfE
YP_001394658.1	electron transport complex protein RnfA
YP_001394659.1	electron transport complex protein RnfB
YP_001394664.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_001394665.1	anthranilate synthase component II
YP_001394666.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001394667.1	indole-3-glycerol phosphate synthase; involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_001394668.1	N-(5'-phosphoribosyl)anthranilate isomerase
YP_001394669.1	tryptophan synthase beta chain; catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_001394670.1	tryptophan synthase alpha chain; catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_001394674.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001394676.1	predicted phosphoribosylformylglycinamidine synthase
YP_001394683.1	ATP phosphoribosyltransferase, regulatory subunit
YP_001394684.1	ATP phosphoribosyltransferase; short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_001394685.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_001394686.1	histidinol-phosphate aminotransferase
YP_001394687.1	imidazoleglycerol-phosphate dehydratase
YP_001394688.1	imidazole glycerol phosphate synthase subunit; with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_001394689.1	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_001394690.1	imidazole glycerol phosphate synthase subunit; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_001394691.1	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers
YP_001394692.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_001394708.1	predicted cysteine desulfurase
YP_001394709.1	NifU-like protein
YP_001394714.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001394716.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_001394718.1	ferric uptake regulation protein
YP_001394725.1	predicted RNA polymerase sigma-E factor precursor; sigma-28; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell after engulfment
YP_001394726.1	predicted twitching motility protein
YP_001394728.1	cell division protein FtsA
YP_001394729.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_001394731.1	RNA polymerase sigma-E factor precursor; sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation
YP_001394732.1	RNA polymerase sigma-G factor; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin
YP_001394736.1	predicted transcriptional regulator
YP_001394737.1	predicted phosphate regulon sensor protein
YP_001394738.1	predicted extracellular phosphate-binding protein
YP_001394739.1	predicted phosphate transport system permease protein
YP_001394740.1	predicted phosphate transport system permease protein
YP_001394741.1	predicted phosphate import ATP-binding protein
YP_001394742.1	predicted phosphate transport system protein
YP_001394744.1	predicted phosphate permease
YP_001394746.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001394747.1	predicted glycerol-3-phosphate dehydrogenase; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_001394755.1	Essential for recycling GMP and indirectly, cGMP
YP_001394756.1	Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_001394757.1	predicted phosphopantothenoylcysteine synthase/decarboxylase; catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_001394758.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_001394759.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_001394760.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_001394763.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_001394766.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_001394767.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_001394770.1	required for 70S ribosome assembly
YP_001394774.1	catalyzes branch migration in Holliday junction intermediates
YP_001394776.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_001394780.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
YP_001394781.1	acetate kinase
YP_001394783.1	ribosomal protein L32; some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_001394784.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_001394785.1	carries the fatty acid chain in fatty acid biosynthesis
YP_001394786.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_001394789.1	predicted cell division protein
YP_001394792.1	ribosomal protein S16; binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_001394794.1	Essential for efficient processing of 16S rRNA
YP_001394795.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001394796.1	ribosomal protein L19; this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001394798.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
YP_001394799.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_001394805.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_001394806.1	predicted transcriptional repressor CodY; CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
YP_001394807.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_001394808.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_001394809.1	Catalyzes the phosphorylation of UMP to UDP
YP_001394810.1	predicted ribosome recycling factor; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_001394811.1	predicted undecaprenyl pyrophosphate synthetase; catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
YP_001394813.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_001394815.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_001394816.1	DNA polymerase III; catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity
YP_001394817.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_001394818.1	transcription elongation protein; modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_001394821.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_001394822.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_001394824.1	predicted tRNA pseudouridine synthase B; catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_001394825.1	predicted riboflavin biosynthesis protein; catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_001394826.1	ribosomal protein S15; primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_001394827.1	polyribonucleotide nucleotidyltransferase
YP_001394830.1	aspartokinase; catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive
YP_001394832.1	DNA translocase
YP_001394834.1	predicted CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
YP_001394835.1	RecA protein; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_001394836.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_001394838.1	catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate
YP_001394841.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001394842.1	predicted phosphocarrier protein
YP_001394844.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_001394846.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_001394847.1	glyceraldehyde-3-phosphate dehydrogenase
YP_001394848.1	predicted D-alanyl-D-alanine carboxypeptidase precursor
YP_001394857.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_001394859.1	sensor kinase
YP_001394860.1	transcriptional regulator
YP_001394861.1	potassium-transporting ATPase, a chain; catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_001394862.1	potassium-transporting ATPase, b chain; One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_001394863.1	potassium-transporting ATPase, c chain; one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex
YP_001394864.1	related to purH
YP_001394865.1	related to purH
YP_001394871.1	predicted ribosomal large subunit pseudouridine synthase D
YP_001394879.1	predicted bifunctional HPr kinase/phosphorylase; catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
YP_001394929.1	catalyzes the removal of amino acids from the N termini of peptides
YP_001394936.1	catalyzes the formation of fumarate from aspartate
YP_001394937.1	UDP-glucose 4-epimerase
YP_001394938.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001394943.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_001394944.1	bifunctional arginine biosynthesis protein
YP_001394945.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_001394946.1	acetylornithine aminotransferase
YP_001394948.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_001394956.1	predicted cytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_001394957.1	these proteins appear to have resulted from a fusion of lytB and rpsA; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_001394958.1	predicted S-adenosylmethionine decarboxylase proenzyme; Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
YP_001394960.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001394963.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_001394964.1	This protein performs the mismatch recognition step during the DNA repair process
YP_001394965.1	DNA mismatch repair protein MutL
YP_001394966.1	predicted tRNA delta(2)-isopentenylpyrophosphate transferase; IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_001394969.1	predicted LexA repressor; Represses a number of genes involved in the response to DNA damage
YP_001394972.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_001394988.1	predicted oligo-1,6-glucosidase
YP_001394991.1	ferrous iron transport protein
YP_001394994.1	translation initiation factor IF-3
YP_001394995.1	predicted Na(+)/H(+) antiporter
YP_001394998.1	purine nucleoside phosphorylase
YP_001394999.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
YP_001395004.1	bicunctional aldehyde-alcohol dehydrogenase
YP_001395007.1	acetolactate synthase, small subunit
YP_001395008.1	acetolactate synthase, large subunit
YP_001395009.1	glutamate synthase, small subunit
YP_001395010.1	glutamate synthase, large subunit
YP_001395013.1	aspartate 1-decarboxylase precursor; Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_001395015.1	nucleoside diphosphate kinase
YP_001395021.1	homoserine O-succinyltransferase
YP_001395022.1	cystathionine gamma-synthase
YP_001395023.1	S-adenosylmethionine synthetase
YP_001395025.1	thiamine-phosphate pyrophosphorylase
YP_001395026.1	thiazole biosynthesis protein; in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center
YP_001395027.1	thiazole biosynthesis protein; functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_001395028.1	thiamine biosynthesis protein; catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate
YP_001395029.1	sulfur carrier protein
YP_001395083.1	predicted dihydroxy-acid dehydratase; catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_001395086.1	predicted biotin synthase; catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine
YP_001395091.1	predicted spore germination protein
YP_001395092.1	predicted spore germination protein
YP_001395093.1	predicted spore germination protein
YP_001395109.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
YP_001395133.1	vanadium nitrogenase associated protein N
YP_001395134.1	vanadium nitrogenase associated protein E
YP_001395135.1	nitrogenase vanadium-iron protein, beta chain
YP_001395136.1	nitrogenase vanadium-iron protein, delta chain
YP_001395137.1	nitrogenase vanadium-iron protein, alpha chain
YP_001395138.1	nitrogenase iron protein; nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; alternative NifH, may be molybdenum-independent
YP_001395139.1	FeMo cofactor biosynthesis protein
YP_001395147.1	homocitrate synthase, alpha subunit
YP_001395148.1	homocitrate synthase, omega subunit
YP_001395152.1	predicted methionine synthase; catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions
YP_001395153.1	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_001395159.1	dihydrolipoyl dehydrogenase
YP_001395160.1	lipoate-protein ligase A
YP_001395161.1	glycine dehydrogenase, subunit 2; acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein
YP_001395162.1	glycine dehydrogenase, subunit 1
YP_001395163.1	glycine cleavage system H protein; part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_001395164.1	aminomethyltransferase
YP_001395166.1	predicted thiamine biosynthesis protein; required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_001395185.1	sulfate adenylyltransferase
YP_001395186.1	sulfate adenylyltransferase; with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_001395188.1	adenylylsulfate reductase; catalyzes the reduction of adenosine 5'-phosphosulfate to AMP and sulfite
YP_001395189.1	adenylyl-sulfate kinase
YP_001395190.1	sulfate import ATP-binding protein
YP_001395191.1	sulfate transport system permease protein
YP_001395192.1	sulfate transport system permease protein
YP_001395193.1	sulfate-binding protein
YP_001395415.1	rubrerythrin
YP_001395419.1	predicted spore germination protein
YP_001395447.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
YP_001395481.1	CapI protein
YP_001395482.1	UDP-glucose 6-dehydrogenase
YP_001395485.1	3-oxoacyl-[acyl-carrier-protein] reductase
YP_001395486.1	acetolactate synthase, large subunit
YP_001395496.1	flagellar hook-associated protein
YP_001395497.1	flagellar protein FliS
YP_001395499.1	predicted flagellar protein
YP_001395501.1	binds to flagellin and appears to stabilize flagellin during flagella assembly
YP_001395502.1	flagellin
YP_001395504.1	flagellin
YP_001395506.1	negative regulator of flagellin synthesis
YP_001395507.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_001395508.1	flagellar motor switch protein
YP_001395509.1	chemotaxis protein
YP_001395511.1	chemotaxis protein
YP_001395512.1	chemotaxis histidine kinase
YP_001395513.1	chemotaxis protein methyltransferase
YP_001395514.1	chemotaxis response regulator protein-glutamate methylesterase
YP_001395515.1	chemotaxis protein; catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors
YP_001395516.1	chemotaxis protein
YP_001395518.1	predicted branched-chain-amino-acid aminotransferase
YP_001395522.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001395523.1	single-stranded-DNA-specific exonuclease recJ
YP_001395526.1	DNA gyrase subunit A; decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001395527.1	DNA gyrase subunit B; decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001395540.1	3-isopropylmalate dehydrogenase
YP_001395541.1	3-isopropylmalate dehydratase small subunit
YP_001395542.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis
YP_001395543.1	2-isopropylmalate synthase
YP_001395548.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_001395549.1	riboflavin synthase beta chain; RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_001395550.1	riboflavin biosynthesis protein
YP_001395551.1	riboflavin synthase alpha chain
YP_001395552.1	riboflavin biosynthesis protein
YP_001395573.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_001395583.1	predicted dihydrofolate reductase
YP_001395587.1	predicted thymidylate synthase
YP_001395595.1	chaperone protein; molecular chaperone
YP_001395615.1	predicted cation-transporting ATPase
YP_001395623.1	predicted cation-transporting ATPase
YP_001395635.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_001395636.1	predicted exopolyphosphatase
YP_001395637.1	predicted exopolyphosphatase
YP_001395642.1	converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines
YP_001395651.1	dihydrolipoyl dehydrogenase (E3 component of pyruvatedehydrogenase complex)
YP_001395652.1	dihydrolipoyllysine-residue acetyltransferase (E2 component of pyruvatedehydrogenase complex)
YP_001395653.1	pyruvate dehydrogenase E1 component, beta subunit
YP_001395654.1	pyruvate dehydrogenase E1 component, alpha subunit
YP_001395656.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_001395657.1	lipoyltransferase
YP_001395691.1	predicted peptidyl-prolyl cis-trans isomerase
YP_001395693.1	predicted asparagine synthetase; functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP
YP_001395695.1	predicted undecaprenyl-diphosphatase; BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_001395711.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_001395713.1	hydrogenase maturation protein HydF
YP_001395714.1	catalyzes the formation of fumarate from aspartate
YP_001395718.1	ClpA homolog protein
YP_001395719.1	ATP-dependent protease adaptor protein ClpS
YP_001395720.1	chaperone protein
YP_001395721.1	chaperone protein
YP_001395723.1	chaperone protein
YP_001395724.1	chaperone protein
YP_001395757.1	carbamoyl-phosphate synthase large chain; four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_001395758.1	carbamoyl-phosphate synthase large chain; catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_001395759.1	ornithine carbamoyltransferase
YP_001395762.1	predicted ATP-dependent DNA helicase
YP_001395782.1	predicted dihydroorotate dehydrogenase; catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines
YP_001395786.1	N-carbamoyl-L-amino acid hydrolase; allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide
YP_001395788.1	1,3-propanediol dehydrogenase
YP_001395790.1	agmatinase
YP_001395791.1	NADP-dependent malic enzyme
YP_001395794.1	member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
YP_001395797.1	glutamine amidotransferase, subunit PdxT; with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
YP_001395798.1	pyridoxal biosynthesis protein PdxS; with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
YP_001395817.1	predicted peptide methionine sulfoxide reductase; this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
YP_001395825.1	predicted hydroxylamine reductase; catalyzes the reduction of hydroxylamine to ammonia and water
YP_001395842.1	nitrogenase iron-molybdenum cofactor biosynthesis protein NifE
YP_001395843.1	nitrogenase iron-molybdenum cofactor biosynthesis protein NifE
YP_001395844.1	nitrogenase iron protein
YP_001395846.1	SugE protein homolog
YP_001395849.1	predicted N-acylneuraminate cytidylyltransferase
YP_001395857.1	predicted dTDP-glucose 4,6-dehydratase
YP_001395879.1	predicted isochorismatase
YP_001395882.1	catalyzes the ATP-dependent transport of cobalt
YP_001395910.1	3-hydroxybutyryl-CoA dehydratase
YP_001395916.1	predicted arsenate reductase
YP_001396033.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_001396036.1	peptide deformylase
YP_001396066.1	predicted phosphoribosylamine--glycine ligase; catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_001396067.1	predicted bifunctional purine biosynthesis protein purH; involved in de novo purine biosynthesis
YP_001396068.1	predicted phosphoribosylglycinamide formyltransferase; glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_001396069.1	phosphoribosylformylglycinamidine cyclo-ligase; catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_001396070.1	predicted amidophosphoribosyltransferase precursor; Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_001396071.1	predicted phosphoribosylaminoimidazole-succinocarboxamide synthase; catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_001396072.1	predicted phosphoribosylaminoimidazole carboxylase catalytic subunit
YP_001396080.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_001396082.1	predicted phosphoenolpyruvate carboxykinase; PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_001396085.1	chaperone
YP_001396104.1	predicted cell division protein FtsH homolog
YP_001396108.1	ferric uptake regulation protein
YP_001396115.1	predicted beta-lactam-inducible penicillin-binding protein
YP_001396117.1	L-allo-threonine aldolase
YP_001396118.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_001396119.1	glutamate 5-kinase
YP_001396120.1	pyrroline-5-carboxylate reductase
YP_001396121.1	predicted H(+)/Cl(-) exchange transporter
YP_001396122.1	predicted branched-chain amino binding protein precursor
YP_001396123.1	predicted branched-chain amino acid transport ATP-binding protein
YP_001396124.1	predicted branched-chain amino acid transport ATP-binding protein
YP_001396125.1	predicted branched-chain amino acid transport system, permease protein
YP_001396126.1	predicted branched-chain amino acid transport system, permease protein
YP_001396128.1	peptide deformylase
YP_001396147.1	predicted spore germination protein
YP_001396148.1	predicted spore germination protein
YP_001396149.1	predicted spore germination protein
YP_001396152.1	malate dehydrogenase
YP_001396154.1	superoxide dismutase [Fe]
YP_001396160.1	deoxyribose-phosphate aldolase
YP_001396163.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001396164.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001396167.1	nitrogenase molybdenum-iron protein, beta chain
YP_001396168.1	nitrogenase molybdenum-iron protein, beta chain
YP_001396169.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001396171.1	KipI antagonist
YP_001396172.1	kinase A inhibitor
YP_001396174.1	methionine aminopeptidase
YP_001396175.1	high molecular weight rubredoxin
YP_001396178.1	predicted 3-hydroxybutyryl-CoA dehydrogenase
YP_001396182.1	predicted dihydrodipicolinate reductase
YP_001396194.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_001396212.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_001396225.1	predicted guanylate kinase
YP_001396231.1	predicted spore germination protein
YP_001396285.1	beta-lactamase, type I precursor
YP_001396290.1	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole
YP_001396291.1	predicted precorrin-2 dehydrogenase; catalyzes the formation of siroheme from precorrin-2
YP_001396292.1	cobalamin biosynthesis protein CobD; CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YP_001396296.1	D-alanine-D-alanine ligase A; D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_001396298.1	phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_001396299.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
YP_001396300.1	hydroxyethylthiazole kinase
YP_001396301.1	phosphomethylpyrimidine kinase
YP_001396375.1	pyruvate:ferredoxin oxidoreductase
YP_001396376.1	pyruvate:ferredoxin oxidoreductase
YP_001396377.1	pyruvate:ferredoxin oxidoreductase
YP_001396378.1	pyruvate:ferredoxin oxidoreductase
YP_001396392.1	RNA polymerase sigma-54 factor; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_001396393.1	NAD-dependent 4-hydroxybutyrate dehydrogenase
YP_001396394.1	succinate semialdehyde dehydrogenase
YP_001396395.1	succinyl-CoA:coenzyme A transferase
YP_001396396.1	predicted transporter
YP_001396397.1	4-hydroxybutyrate coenzyme A transferase
YP_001396399.1	4-hydroxybutyryl-CoA dehydratase
YP_001396405.1	predicted long-chain-fatty-acid-CoA ligase
YP_001396406.1	acyl carrier protein
YP_001396429.1	NADP-specific glutamate dehydrogenase; converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_001396441.1	predicted tryptophan synthase, beta chain; catalyzes the formation of L-tryptophan from indole and L-serine
YP_001396454.1	fusion of beta chain molybdenum-iron nitrogenase and FeMo cofactor biosynthesis protein
YP_001396455.1	nitrogenase iron-molybdenum cofactor biosynthesis protein NifE; functions with NifN to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe
YP_001396456.1	nitrogenase molybdenum-iron protein, beta chain
YP_001396457.1	nitrogenase molybdenum-iron protein, alpha chain
YP_001396460.1	nitrogenase iron protein
YP_001396463.1	predicted molybdenum-pterin binding protein
YP_001396465.1	predicted molybdate-binding extracellular protein precursor
YP_001396466.1	predicted molybdate-binding extracellular protein precursor
YP_001396498.1	4-aminobutyrate aminotransferase
YP_001396505.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001396506.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_001396507.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001396509.1	D-tyrosyl-tRNA deacylase; hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_001396510.1	GTP pyrophosphokinase
YP_001396511.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_001396515.1	predicted protein-export membrane protein; forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_001396516.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_001396521.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_001396522.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_001396523.1	Holliday junction DNA helicase; promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001396524.1	Holliday junction DNA helicase; plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_001396533.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore.
YP_001396534.1	binds to sigma F preventing its association with RNA polymerase during sporulation
YP_001396535.1	anti-sigma F factor antagonist
YP_001396536.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_001396556.1	predicted capsular polysaccharide biosynthesis protein
YP_001396557.1	UTP--glucose-1-phosphate uridylyltransferase
YP_001396559.1	predicted phosphoglucomutase
YP_001396560.1	predicted arginine decarboxylase
YP_001396562.1	MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange
YP_001396570.1	phenylalanyl-tRNA synthetase, subunit B; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_001396571.1	phenylalanyl-tRNA synthetase, subunit A; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_001396573.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001396575.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_001396579.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_001396580.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_001396581.1	aspartate-semialdehyde dehydrogenase
YP_001396584.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_001396585.1	predicted 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
YP_001396586.1	predicted single stranded DNA binding protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_001396592.1	predicted folylpolyglutamate synthase
YP_001396593.1	Valyl-tRNA synthetase; valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_001396695.1	type A flavoprotein with an additional rubredoxin domain
YP_001396703.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_001396709.1	predicted transcription elongation factor
YP_001396710.1	predicted undecaprenyl pyrophosphate synthase
YP_001396715.1	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
YP_001396722.1	predicted GTP-binding protein; binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_001396723.1	ATP-dependent protease La
YP_001396724.1	ATP-dependent Clp protease, ATP-binding subunit; binds and unfolds substrates as part of the ClpXP protease
YP_001396725.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_001396726.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_001396729.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001396730.1	dihydroorotate dehydrogenase
YP_001396731.1	responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+)
YP_001396732.1	type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_001396733.1	dihydroorotase
YP_001396734.1	aspartate carbamoyltransferase regulatory chain; involved in the allosteric regulation of aspartate carbamoyltransferase
YP_001396735.1	aspartate carbamoyltransferase; catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_001396749.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_001396750.1	predicted ribonuclease R
YP_001396752.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_001396753.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_001396754.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_001396755.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_001396799.1	predicted cobalt transport protein
YP_001396800.1	predicted cobalt transport protein
YP_001396801.1	predicted cobalt transport protein; periplasmic cobalt binding component of the cobalt transport system
YP_001396802.1	predicted cobalt transport protein; catalyzes the ATP-dependent transport of cobalt
YP_001396805.1	superoxide dismutase [Mn/Fe]
YP_001396809.1	1,3-propanediol dehydrogenase
YP_001396812.1	DNA polymerase IV
YP_001396825.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_001396826.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_001396827.1	predicted hydrogenase maturation factor
YP_001396830.1	predicted oligopeptide-binding protein oppA precursor
YP_001396832.1	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B; allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001396833.1	glutamyl-tRNA amidotransferase, subunit A; allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001396834.1	glutamyl-tRNA amidotransferase, subunit C; allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_001396844.1	DNA ligase
YP_001396846.1	ATP-dependent DNA helicase
YP_001396848.1	ribosomal small subunit pseudouridine synthase A
YP_001396853.1	glucose-6-phosphate isomerase
YP_001396855.1	glycogen biosynthesis protein
YP_001396856.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_001396857.1	amylopullulanase precursor
YP_001396858.1	glycogen phosphorylase
YP_001396859.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
YP_001396860.1	1,4-alpha-glucan branching enzyme
YP_001396875.1	predicted 3-oxoacyl-synthase
YP_001396878.1	electron transfer flavoprotein, alpha subunit
YP_001396879.1	electron transfer flavoprotein, beta subunit
YP_001396888.1	predicted amino acid transport protein
YP_001396889.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_001396920.1	pyruvate kinase
YP_001396921.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_001396922.1	DNA polymerase III, alpha subunit; catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria
YP_001396927.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_001396928.1	excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_001396933.1	excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_001396934.1	excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_001396939.1	predicted transketolase, subunit B
YP_001396940.1	predicted transketolase, subunit A
YP_001396941.1	related to PemK-family
YP_001396943.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
YP_001396946.1	phosphopantetheinyl transferase; Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_001396952.1	similar to YegS from E. coli
YP_001396955.1	phosphatidylserine synthase
YP_001396957.1	butyryl-CoA: acetate CoA transferase
YP_001396961.1	fructose-bisphosphate aldolase
YP_001396964.1	related to DnaJ
YP_001396966.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001396973.1	transcriptional accessory protein
YP_001396978.1	peptide chain release factor B; catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA
YP_001396979.1	protein translocase subunit secA; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_001396981.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_001396982.1	related to tyrosine recombinase
YP_001396986.1	predicted UDP-galactopyranose mutase
YP_001397012.1	related to Mrp-family
YP_001397029.1	related to competence protein
YP_001397035.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_001397041.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1; adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001397043.1	F1Fo ATPase, subunit C; produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex
YP_001397044.1	F1Fo ATPase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001397045.1	F1Fo ATPase, subunit G; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_001397046.1	F1Fo ATPase, subunit A; produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_001397047.1	F1Fo ATPase, subunit H; Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_001397048.1	F1Fo ATPase, subunit F; produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel
YP_001397049.1	F1Fo ATPase, subunit E; produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0
YP_001397050.1	F1Fo ATPase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_001397051.1	F1Fo ATPase, subunit I
YP_001397052.1	acetoacetyl-CoA thiolase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_001397053.1	acetoacetyl-CoA thiolase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_001397054.1	acetoacetyl-CoA thiolase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_001397055.1	predicted UDP-N-acetylglucosamine 2-epimerase
YP_001397058.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_001397059.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_001397061.1	related to Sua5
YP_001397062.1	predicted zinc transporter
YP_001397064.1	peptide chain release factor 1 (RF-1); recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_001397068.1	50S ribosomal protein L31
YP_001397069.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_001397071.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_001397075.1	predicted UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
YP_001397080.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_001397081.1	catalyze the formation of cyanophycin which may act to store excess nitrogen
YP_001397082.1	cyanophycinase
YP_001397086.1	predicted spore coat protein
YP_001397100.1	responsible for recognizing base lesions in the genome and initiating base excision DNA repair
YP_001397102.1	predicted mannose-1-phosphate guanylyltransferase
YP_001397108.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)
YP_001397112.1	predicted anaerobic ribonucleoside-triphosphate reductase activating protein
YP_001397113.1	predicted anaerobic ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_001397118.1	predicted dimethyladenosine transferase; catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_001397122.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_001397130.1	predicted 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
YP_001397133.1	related to phage shock protein A
YP_001397137.1	superoxide reductase
YP_001397138.1	rubrerythrin
YP_001397144.1	predicted chemotaxis protein
YP_001397145.1	predicted chemotaxis protein
YP_001397149.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_001397151.1	predicted thymidylate kinase
YP_001397152.1	predicted arginine decarboxylase
YP_001397157.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_001397171.1	sugar fermentation stimulation protein homolog; Regulatory factor involved in maltose metabolism
YP_001397174.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_001397176.1	DNA polymerase III subunit gamma/tau; catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_001397177.1	hydrogenase maturation protein HydG; in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain
YP_001397248.1	18 kDa heat shock protein
YP_001397249.1	unwinds double stranded DNA
YP_001397251.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_001397255.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001397256.1	predicted single-strand binding protein
YP_001397257.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_001397263.1	predicted chromosome partitioning protein
YP_001397264.1	predicted chromosome partitioning protein
YP_001397266.1	glucose inhibited division protein B; glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_001397267.1	glucose inhibited division protein A; GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_001397268.1	tRNA modification GTPase; in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_001397270.1	predicted membrane protein OxaA; functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_001397272.1	ribonuclease P protein component; protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_001397273.1	in Escherichia coli transcription of this gene is enhanced by polyamines