-- dump date 20140619_051152 -- class Genbank::CDS -- table cds_note -- id note NP_938410.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_938411.2 binds the polymerase to DNA and acts as a sliding clamp NP_938412.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_938413.1 Similar to Mycobacterium paratuberculosis hypothetical 17.5 kDa protein TR:Q9L7L4 (EMBL:AF222789) (166 aa) fasta scores: E(): 5.6e-18, 45.45% id in 143 aa NP_938414.1 negatively supercoils closed circular double-stranded DNA NP_938415.1 Doubtful CDS. No significant database matches NP_938416.1 Doubtful CDS. No significant database matches NP_938417.1 Similar to Streptomyces coelicolor hypothetical 7.1 kDa protein SC10A5.13 TR:O54104 (EMBL:AL021529) (64 aa) fasta scores: E(): 0.18, 52.5% id in 40 aa NP_938418.1 negatively supercoils closed circular double-stranded DNA NP_938419.1 Similar in its C-terminal region to Mycobacterium leprae hypothetical 32.2 kDa protein MLB1770.07 or ML0007 TR:O32870 (EMBL:Z70722) (303 aa) fasta scores: E(): 9.9e-08, 36.28% id in 113 aa NP_938420.1 Similar to Escherichia coli glc operon transcriptional activator GlcC or B2980 SW:GLCC_ECOLI (P52072) (254 aa) fasta scores: E(): 1.2e-05, 23.5% id in 234 aa NP_938421.1 Similar to Escherichia coli L-lactate permease LldP or LctP or B3603 SW:LLDP_ECOLI (P33231) (551 aa) fasta scores: E(): 2.4e-68, 40.1% id in 561 aa NP_938423.1 Low similarity to Staphylococcus aureus subsp aureus N315 SA0639 protein TR:Q99VT7 (EMBL:AP003131) (543 aa) fasta scores: E(): 3e-23, 25.56% id in 485 aa NP_938424.1 Similar to Escherichia coli, and Escherichia coli O157:H7 probable transport ATP-binding protein MsbA or B0914 or Z1260 or ECS0997 SWALL:MSBA_ECOLI (SWALL:P27299) (582 aa) fasta scores: E(): 7e-30, 26.73% id in 561 aa, and to Pasteurella multocida hypothetical protein PM1473 TR:Q9CKX8 (EMBL:AE006183) (552 aa) fasta scores: E(): 6.1e-33, 27.97% id in 554 aa NP_938425.1 No database matches. Possible membrane protein NP_938426.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938427.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938428.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938429.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938430.1 Similar to Streptomyces coelicolor probable solute-binding lipoprotein SC8F11.05 TR:Q9KZH3 (EMBL:AL353864) (340 aa) fasta scores: E(): 2.8e-63, 54.98% id in 331 aa NP_938431.1 Similar to Streptomyces coelicolor probable ABC transport protein, membrane component SC8F11.06 TR:Q9KZH2 (EMBL:AL353864) (359 aa) fasta scores: E(): 1.1e-72, 57.66% id in 326 aa NP_938432.1 Similar to Streptomyces coelicolor probable ABC transport protein, ATP-binding component SC8F11.07 TR:Q9KZH1 (EMBL:AL353864) (330 aa) fasta scores: E(): 2.8e-51, 62.15% id in 251 aa NP_938433.1 Possible membrane protein. No database matches NP_938434.1 Similar to Mycobacterium tuberculosis probable peptidyl-prolyl cis-trans isomerase A PpiA or Rv0009 or MT0011 or MTCY10H4.08 SW:PPIA_MYCTU (P71578) (182 aa) fasta scores: E(): 4.7e-52, 78.36% id in 171 aa NP_938435.1 Similar to Streptococcus mutans transposase (fragment) TR:Q9ZHF4 (EMBL:AF065413) (75 aa) fasta scores: E(): 3.5e-11, 47.22% id in 72 aa NP_938436.1 Similar to Mycobacterium tuberculosis transmembrane protein Rv0110 or MTV031.04 TR:O53632 (EMBL:AL021926) (249 aa) fasta scores: E(): 1.4e-13, 34.19% id in 193 aa NP_938438.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_938439.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate NP_938440.1 Similar to Rhizobium etli thiamine biosynthesis oxidoreductase ThiO SW:THIO_RHIET (O34292) (327 aa) fasta scores: E(): 5.4e-09, 31.67% id in 341 aa NP_938441.1 Similar to Streptomyces coelicolor hypothetical 6.6 kDa protein SC6E10.02 TR:Q9S2N5 (EMBL:AL109661) (66 aa) fasta scores: E(): 1.1e-06, 36.36% id in 66 aa NP_938442.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_938443.1 catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate NP_938444.1 Similar to Escherichia coli phosphomethylpyrimidine kinase ThiD or B2103 SW:THID_ECOLI (P76422) (266 aa) fasta scores: E(): 5.5e-30, 44.9% id in 265 aa NP_938445.1 Similar in its N-terminal region to Pasteurella multocida hypothetical protein PM1127 TR:Q9CLT2 (EMBL:AE006153) (1056 aa) fasta scores: E(): 1.4e-15, 21.94% id in 802 aa NP_938446.1 Similar to Neisseria meningitidis hypothetical protein NMA0630 TR:Q9JVY0 (EMBL:AL162753) (304 aa) fasta scores: E(): 2.7e-22, 37.5% id in 256 aa, and to Pasteurella multocida hypothetical protein PM1126 TR:Q9CLT3 (EMBL:AE006153) (343 aa) fasta scores: E(): 3.5e-22, 32.04% id in 284 aa NP_938447.1 Similar to Pasteurella multocida hypothetical protein PM1125 TR:Q9CLT4 (EMBL:AE006153) (108 aa) fasta scores: E(): 9.3e-07, 42.85% id in 77 aa NP_938448.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938449.1 Similar to the C-terminal region of Rickettsia prowazekii hypothetical protein RP756 SW:Y756_RICPR (Q9ZCI4) (105 aa) fasta scores: E(): 3.4, 33.33% id in 51 aa NP_938450.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938451.1 Similar to Mycobacterium smegmatis transposase TR:O70063 (EMBL:AF036759) (503 aa) fasta scores: E(): 4.7e-88, 50% id in 498 aa. Presents a frameshift at residue 65 NP_938452.1 Similar to Corynebacterium jeikeium transposase B TnpB TR:AAK67710 (EMBL:AY036070) (302 aa) fasta scores: E(): 1.2e-06, 45.45% id in 55 aa, and to Escherichia coli O157:H7 EDL933 partial transposase Z1207 TR:AAG55352 (EMBL:AE005276) (82 aa) fasta scores: E(): 5.2e-05, 38% id in 50 aa NP_938453.1 Doubtful CDS. No significant database matches NP_938454.1 Doubtful CDS. No significant database matches NP_938455.1 integral membrane protein involved in inhibition of the Z-ring formation NP_938456.1 Similar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa NP_938457.1 Similar to Mycobacterium leprae probable serine/threonine-protein kinase PnkA or ML0017 SW:PKNA_MYCLE (P54743) (437 aa) fasta scores: E(): 4e-37, 41.99% id in 431 aa NP_938458.1 Similar to Mycobacterium leprae penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa NP_938459.1 Similar to Mycobacterium tuberculosis probable cell division protein FtsW or Rv0017c or MT0020 or MTCY10H4.17c SW:FTSW_MYCTU (P71587) (469 aa) fasta scores: E(): 8.7e-72, 48.61% id in 434 aa, and to Escherichia coli rod shape-determining protein MrdB or RodA or B0634 or Z0780 or ECS0672 SW:RODA_ECOLI (P15035) (370 aa) fasta scores: E(): 8.5e-19, 26.57% id in 365 aa NP_938460.1 Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa NP_938461.1 Similar to Mycobacterium leprae hypothetical 17.2 kDa protein MLB1770.14c or ML0021 TR:Q50189 (EMBL:Z70722) (155 aa) fasta scores: E(): 2.3e-13, 35% id in 160 aa NP_938462.1 Similar to Streptomyces coelicolor hypothetical 30.8 kDa protein SCH69.13 TR:Q9XA21 (EMBL:AL079308) (290 aa) fasta scores: E(): 3.1e-11, 27.6% id in 297 aa NP_938463.1 Similar to Enterococcus hirae probable copper exporting ATPase B CopB SW:COPB_ENTHR (P05425) (745 aa) fasta scores: E(): 2.2e-94, 43.228% id in 731 aa, and to Mycobacterium tuberculosis probable cation-transporting ATPase V CtpV or Rv0969 or MT0997 or MTCY10D7.05c SW:CTPV_MYCTU (P77894) (770 aa) fasta scores: E(): 2e-69, 40.092% id in 651 aa NP_938464.1 Similar to Deinococcus radiodurans conserved hypothetical protein DR2452 TR:Q9RRN6 (EMBL:AE002074) (68 aa) fasta scores: E(): 0.0038, 43.103% id in 58 aa, and to Streptococcus pyogenes copper chaperone-copper transport operon CopZ or SPY1714 TR:Q99YG6 (EMBL:AE006600) (67 aa) fasta scores: E(): 0.0065, 40.000% id in 60 aa, and to Pseudomonas syringae Plasmid pPaCu1 copper resistance operon ORFH protein TR:Q9KWM7 (EMBL:AB033420) (65 aa) fasta scores: E(): 0.025, 40.000% id in 60 aa, and to Candida albicans copper-transporting p-type ATPase Ccc2 TR:AAK52331 (EMBL:AY033084) (1204 aa) fasta scores: E(): 0.03, 28.571% id in 84 aa NP_938465.1 Similar to Escherichia coli sensor protein BaeS or B2078 SW:BAES_ECOLI (P30847) (467 aa) fasta scores: E(): 1.8e-28, 33.333% id in 372 aa NP_938466.1 Similar to Enterococcus faecalis VicR protein TR:Q9REA7 (EMBL:AJ012050) (283 aa) fasta scores: E(): 5.5e-35, 44.978% id in 229 aa, to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 3e-34, 42.918% id in 233 aa, and to Bacillus subtilis hypothetical sensory transduction protein YycF SW:YYCF_BACSU (P37478) (235 aa) fasta scores: E(): 1.8e-33, 43.478% id in 230 aa NP_938467.1 No database matches NP_938468.1 Similar to Mycobacterium tuberculosis CDC1551 copper-binding protein, MT0869 TR:AAK45112 (EMBL:AE006975) (504 aa) fasta scores: E(): 9e-68, 43.028% id in 502 aa, and to Nicotiana tabacum L-ascorbate oxidase precursor Aao SW:ASO_TOBAC (Q40588) (578 aa) fasta scores: E(): 2.5e-14, 25.344% id in 509 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRQFLL) at the N-terminal region NP_938469.1 Weak similarities to Streptomyces coelicolor DNA polymerase III, epsilon chain SCI8.12 TR:Q9RJ41 (EMBL:AL132644) (328 aa) fasta scores: E(): 2.7, 42.22% id in 45 aa, and to Thermotoga maritima DNA polymerase III PolC-type PolC or TM0576 SW:DPO3_THEMA (Q9ZHF6) (1367 aa) fasta scores: E(): 9.3, 39.58% id in 48 aa NP_938472.1 Weakly similar to Rhizobium loti MLR2640 protein TR:Q98HZ4 (EMBL:AP003000) (140 aa) fasta scores: E(): 4.2, 27.1% id in 107 aa; Conserved hypothetical protein NP_938473.1 Doubtful CDS. No significant database matches NP_938479.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938480.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938481.1 Possible secreted protein. No database matches NP_938482.1 Doubtful CDS. No significant database matches NP_938483.1 Doubtful CDS. Possible membrane protein. No database matches NP_938484.1 Weakly similar to Euhadra herklotsi NADH dehydrogenase subunit 1 TR:O21342 (EMBL:Z71695) (296 aa) fasta scores: E(): 0.57, 24.16% id in 120 aa NP_938485.1 Similar to Deinococcus radiodurans transcriptional regulator, HTH_3 family DR2259 TR:Q9RS68 (EMBL:AE002058) (82 aa) fasta scores: E(): 1.3e-10, 47.67% id in 86 aa NP_938486.1 Weakly similar in its N-terminal region to Bacillus subtilis SpaE TR:O52853 (EMBL:U09819) (251 aa) fasta scores: E(): 0.0095, 21% id in 200 aa NP_938487.1 Similar to Lactococcus lactis NisF TR:Q48597 (EMBL:U17255) (225 aa) fasta scores: E(): 1.3e-25, 43.8% id in 226 aa, and to Staphylococcus epidermidis ABC transporter subunit EpiF TR:Q54002 (EMBL:U77778) (231 aa) fasta scores: E(): 7.1e-21, 38.15% id in 228 aa NP_938488.1 Similar to Streptomyces lividans response regulator homolog TR:P72471 (EMBL:U63847) (225 aa) fasta scores: E(): 2.7e-29, 42.98% id in 221 aa, and to Streptomyces coelicolor two-component system regulator SCH10.18c TR:Q9X8Q7 (EMBL:AL049754) (228 aa) fasta scores: E(): 3e-26, 38.53% id in 218 aa NP_938489.1 Similar to Streptomyces coelicolor two component sensor kinase SC5F7.35c TR:Q9S2S0 (EMBL:AL096872) (416 aa) fasta scores: E(): 2.9e-17, 32.79% id in 308 aa, and to Streptomyces coelicolor two-component system sensor kinase SCH10.17c TR:Q9X8Q6 (EMBL:AL049754) (472 aa) fasta scores: E(): 1.1e-11, 33.61% id in 241 aa NP_938490.1 Probable membrane protein. No database matches NP_938491.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938492.1 Similar to Bacillus subtilis choline transport system permease OpuBB or ProW SW:OPBB_BACSU (Q45461) (217 aa) fasta scores: E(): 3e-14, 30.72% id in 192 aa, and to Mycobacterium tuberculosis transport system permease Rv3756c or MTV025.104c TR:O69722 (EMBL:AL022121) (239 aa) fasta scores: E(): 1.9e-28, 48.32% id in 209 aa NP_938493.1 Similar to Bacillus subtilis choline transport system permease OpuBD or ProZ SW:OPBD_BACSU (P39775) (226 aa) fasta scores: E(): 8.5e-13, 29.44% id in 197 aa, and to Mycobacterium tuberculosis transport system permease Rv3757c or MTV025.105c TR:O69723 (EMBL:AL022121) (229 aa) fasta scores: E(): 4.7e-25, 39.71% id in 209 aa NP_938494.1 Similar to Bacillus subtilis choline transport ATP-binding protein OpuBA or ProV SW:OPBA_BACSU (Q45460) (381 aa) fasta scores: E(): 2.5e-42, 50.58% id in 255 aa, and to Mycobacterium tuberculosis ABC transporter ATP-binding protein Rv3758c or MTV025.106c TR:O69724 (EMBL:AL022121) (376 aa) fasta scores: E(): 1.3e-42, 53.62% id in 248 aa NP_938495.1 Weakly similar to Mycobacterium tuberculosis hypothetical 23.9 kDa protein Rv0444c or MTV037.08C TR:O53729 (EMBL:AL021932) (232 aa) fasta scores: E(): 0.004, 25.94% id in 212 aa NP_938496.1 Similar to Streptomyces coelicolor RNA polymerase sigma factor SCI11.12c TR:Q9S2A7 (EMBL:AL096849) (185 aa) fasta scores: E(): 2.8e-25, 47.36% id in 171 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 3.9e-10, 31.39% id in 172 aa NP_938498.1 Similar to Mycobacterium tuberculosis DipZ protein Rv2874 or MT2942 or MTCY274.05 SW:DIPZ_MYCTU (Q10801) (695 aa) fasta scores: E(): 1.6e-43, 43.65% id in 591 aa NP_938499.1 Similar to Streptomyces coelicolor transcriptional activator TipA or SCE9.20 SW:TIPA_STRCO (P32184) (253 aa) fasta scores: E(): 5.3e-24, 35.85% id in 251 aa NP_938500.1 Similar to Mycobacterium leprae hypothetical protein ML2114 TR:Q9CBE3 (EMBL:AL583924) (56 aa) fasta scores: E(): 1.7e-05, 52.08% id in 48 aa NP_938501.1 Similar to Streptomyces coelicolor peptidase SCI52.18c TR:Q9AD91 (EMBL:AL590507) (445 aa) fasta scores: E(): 1e-31, 32.04% id in 440 aa NP_938502.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine NP_938503.1 Similar to Mycobacterium tuberculosis hypothetical 8.6 kDa protein Rv1590 or MT1625 or MTCY336.14c TR:O06600 (EMBL:Z95586) (79 aa) fasta scores: E(): 4.1e-11, 67.24% id in 58 aa NP_938504.1 Almost identical to previously sequenced Corynebacterium diphtheriae ferrisiderophore receptor Irp6A SWALL:Q8VVA8 (EMBL:AY061890) (395 aa) fasta scores: E(): 8.7e-146, 97.46% id in 395 aa NP_938505.1 Almost identical to previously sequenced Corynebacterium diphtheriae membrane protein permease Irp6B SWALL:Q8VVA7 (EMBL:AY061890) (347 aa) fasta scores: E(): 1e-116, 98.27% id in 347 aa and similar to Rhizobium meliloti iron ABC transporter permease SMB21430 TR:CAC49658 (EMBL:AL603646) (356 aa) fasta scores: E(): 1.6e-55, 50.87% id in 342 aa and to Corynebacterium diphtheriae HmuU SWALL:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 2.1e-36, 40.66% id in 332 aa NP_938506.1 Almost identical to previously sequenced Corynebacterium diphtheriae ATP-binding protein Irp6C SWALL:Q8VVA6 (EMBL:AY061890) (252 aa) fasta scores: E(): 1.4e-79, 99.6% id in 252 aa and similar to Escherichia coli iron FecE or B4287 SWALL:FECE_ECOLI (SWALL:P15031) (255 aa) fasta scores: E(): 5.7e-19, 37.64% id in 263 aa NP_938507.1 Similar to Corynebacterium glutamicum ATCC 13032 hypothetical protein CGL1283 SWALL:BAB98676 (EMBL:AP005278) (581 aa) fasta scores: E(): 1.8e-63, 45.63% id in 504 aa NP_938508.1 Similar to Bacillus subtilis YdhG protein TR:O05499 (EMBL:D88802) (135 aa) fasta scores: E(): 2.3e-20, 41.46% id in 123 aa NP_938509.1 Similar to Streptomyces griseus deoxyribodipyrimidine photolyase Phr SW:PHR_STRGR (P12768) (455 aa) fasta scores: E(): 3.5e-36, 36.75% id in 468 aa, and to Escherichia coli deoxyribodipyrimidine photolyase PhrB or Phr or B0708 SW:PHR_ECOLI (P00914) (472 aa) fasta scores: E(): 9.9e-32, 34.01% id in 488 aa NP_938510.1 Similar to Staphylococcus aureus subsp aureus N315 hypothetical protein SA2163 TR:Q99RQ4 (EMBL:AP003137) (143 aa) fasta scores: E(): 2.4e-15, 39.16% id in 143 aa NP_938511.1 Similar to Streptomyces coelicolor hypothetical 39.2 kDa protein SCH24.21c TR:Q9X8T5 (EMBL:AL049826) (360 aa) fasta scores: E(): 5e-111, 79.49% id in 356 aa NP_938512.1 Similar to Rhizobium loti MLR6622 protein TR:Q988S0 (EMBL:AP003009) (231 aa) fasta scores: E(): 1.4e-25, 40.99% id in 222 aa NP_938513.1 Similar to Streptomyces coelicolor secreted lipase SCI11.24c TR:Q9S295 (EMBL:AL096849) (290 aa) fasta scores: E(): 6.8e-20, 33.18% id in 223 aa, and to Pseudomonas sp lipase precursor Lip SW:LIP_PSES5 (P25275) (364 aa) fasta scores: E(): 5.6e-05, 28.4% id in 176 aa NP_938514.1 Similar to Thermus aquaticus NADH dehydrogenase Nox SW:NOX_THETH (Q60049) (205 aa) fasta scores: E(): 3.2e-07, 34.18% id in 196 aa NP_938515.1 Similar to Deinococcus radiodurans ATP-dependent DNA helicase RecG-related protein DR2199 TR:Q9RSC6 (EMBL:AE002053) (596 aa) fasta scores: E(): 8.9e-13, 24.04% id in 445 aa NP_938516.1 Similar to parts of Mycobacterium smegmatis TnpA protein TR:Q50440 (EMBL:M76495) (413 aa) fasta scores: E(): 0.8, 44.44% id in 36 aa NP_938517.1 Similar to Streptomyces coelicolor siderophore binding protein SCBAC36F5.26 TR:CAC42862 (EMBL:AL592292) (178 aa) fasta scores: E(): 6.3e-25, 48.48% id in 165 aa NP_938518.1 Similar to Mycobacterium tuberculosis hypothetical 46.1 kDa protein Rv0485 or MT0503 or MTCY20G9.11 SW:Y485_MYCTU (Q11151) (438 aa) fasta scores: E(): 1.4e-12, 32.14% id in 224 aa NP_938519.1 Similar to Streptomyces coelicolor integral membrane protein SCBAC19F3.14 TR:CAC44337 (EMBL:AL596102) (517 aa) fasta scores: E(): 3.6e-47, 37.96% id in 453 aa NP_938520.1 Similar to the C-terminal region of Pseudomonas aeruginosa hypothetical protein PA4923 SW:YDC3_PSEAE (P48636) (195 aa) fasta scores: E(): 3.3e-27, 44.97% id in 189 aa NP_938521.1 Similar to Streptomyces coelicolor conserved hypothetical protein SCBAC36F5.07 TR:CAC42843 (EMBL:AL592292) (562 aa) fasta scores: E(): 3.6e-40, 35.62% id in 553 aa NP_938522.1 Similar to Streptomyces coelicolor regulatory protein SCE50.15 TR:Q9L048 (EMBL:AL163672) (168 aa) fasta scores: E(): 3.3e-18, 41.89% id in 148 aa NP_938523.1 Similar to Escherichia coli AbrB protein or B0715 SW:ABRB_ECOLI (P75747) (348 aa) fasta scores: E(): 3.6e-20, 30.72% id in 345 aa NP_938525.1 Similar to Streptomyces coelicolor hypothetical 26.0 kDa protein SC7A8.24c TR:Q9L2D4 (EMBL:AL137187) (260 aa) fasta scores: E(): 1e-34, 42.8% id in 257 aa NP_938526.1 Similar to Escherichia coli ATP-dependent helicase HrpB or B0148 SW:HRPB_ECOLI (P37024) (809 aa) fasta scores: E(): 2.6e-40, 35.09% id in 815 aa NP_938527.1 Similar to Streptomyces coelicolor sugar acetyltransferase SCBAC25F8.11c TR:CAC42146 (EMBL:AL592126) (193 aa) fasta scores: E(): 2.2e-24, 44.7% id in 170 aa, and to Escherichia coli galactoside O-acetyltransferase LacA or B0342 SWALL:THGA_ECOLI (SWALL:P07464) (203 aa) fasta scores: E(): 2.3e-21, 36.51% id in 178 aa NP_938528.1 Similar to Escherichia coli alkylated DNA repair protein Alkb or AidD or B2212 SW:ALKB_ECOLI (P05050) (216 aa) fasta scores: E(): 1.4e-12, 35.02% id in 237 aa NP_938529.1 Similar to Mycobacterium tuberculosis CDC1551 DNA-3-methyladenine glycosidase I MT1248 TR:AAK45505 (EMBL:AE007001) (204 aa) fasta scores: E(): 8.3e-35, 52.71% id in 184 aa, and to Escherichia coli DNA-3-methyladenine glycosylase I Tag or B3549 SW:3MG1_ECOLI (P05100) (187 aa) fasta scores: E(): 1.5e-25, 44.88% id in 176 aa NP_938530.1 Similar to Mycobacterium tuberculosis oxidoreductase Rv0484c or MT0502 or MTCY20G9.10c SW:Y484_MYCTU (Q11150) (251 aa) fasta scores: E(): 1.2e-45, 57.32% id in 232 aa NP_938532.1 Similar to a region of Corynebacterium glutamicum Ycg4K TR:Q9EUM3 (EMBL:AF164956) (256 aa) fasta scores: E(): 9.2e-09, 75.61% id in 41 aa NP_938533.1 Doubtful CDS. No significant database matches NP_938535.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938536.1 Doubtful CDS. No significant database matches NP_938538.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938540.1 Doubtful CDS. No significant database matches NP_938541.1 Similar to Bacillus subtilis hypothetical 7.9 kDa protein in dnaN-recF intergenic region YaaA SW:YAAA_BACSU (P05650) (71 aa) fasta scores: E(): 2.5e-05, 44.92% id in 69 aa NP_938542.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0934.1 TR:AAK45182 (EMBL:AE006980) (257 aa) fasta scores: E(): 3.3e-32, 41.96% id in 255 aa NP_938543.1 Similar to Streptomyces coelicolor conserved hypothetical protein SC10F4.36c TR:Q9F3M5 (EMBL:AL450350) (94 aa) fasta scores: E(): 8.6e-07, 38.2% id in 89 aa, and to Mycobacterium tuberculosis hypothetical 11.0 kDa protein Rv3204 or MTCY07D11.22c TR:O05862 (EMBL:Z95120) (101 aa) fasta scores: E(): 0.00013, 40% id in 95 aa NP_938546.1 Similar to Mycobacterium tuberculosis CDC1551 endopeptidase, peptidase M13 MT0208 TR:AAK44429 (EMBL:AE006930) (663 aa) fasta scores: E(): 2.9e-89, 46.97% id in 662 aa NP_938547.1 No significant database matches. Possible secreted protein NP_938548.1 No significant database matches. Possible membrane protein NP_938549.1 Similar to Mycobacterium tuberculosis CDC1551 amino acid ABC transporter, amino acid-binding protein, MT3866 TR:AAK48230 (EMBL:AE007181) (343 aa) fasta scores: E(): 2.6e-26, 35.69% id in 311 aa NP_938550.1 No significant database matches. Possible secreted protein NP_938551.1 Similar to Mycobacterium tuberculosis CDC1551 arabinosyl transferase MT3902 TR:AAK48268 (EMBL:AE007183) (1098 aa) fasta scores: E(): 1.3e-49, 38.11% id in 1149 aa NP_938552.1 Similar to Mycobacterium tuberculosis hypothetical 69.5 kDa protein CY13D12.26 Rv3792 or MTCY13D12.26 TR:P72058 (EMBL:Z80343) (643 aa) fasta scores: E(): 3.7e-53, 34.5% id in 652 aa NP_938553.1 Similar to Mycobacterium leprae oxidoreductase ML0108 TR:Q9CDA5 (EMBL:AL583917) (254 aa) fasta scores: E(): 5.6e-50, 57.14% id in 252 aa NP_938554.1 Similar to Mycobacterium tuberculosis CDC1551 oxidoreductase, FAD-binding MT3898 TR:AAK48263 (EMBL:AE007183) (463 aa) fasta scores: E(): 4.2e-118, 67.57% id in 478 aa NP_938556.1 No significant database matches. Possible membrane protein NP_938558.1 Similar to Mycobacterium tuberculosis hypothetical 13.4 kDa protein Rv3789 or MT3897 or MTCY13D12.23 SW:Y1I9_MYCTU (P72055) (121 aa) fasta scores: E(): 4.2e-17, 48.78% id in 123 aa NP_938559.1 No significant database matches. Note: Also similar to DIP2059 (271 aa) E(): 1e-38; 44.747% identity in 257 aa overlap NP_938560.1 Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT3891 TR:AAK48256 (EMBL:AE007182) (304 aa) fasta scores: E(): 1.8e-71, 62.17% id in 304 aa NP_938561.1 Similar to Treponema pallidum periplasmic zinc-binding protein TroA or TroMP1 or TP0163 SWALL:TROA_TREPA (SWALL:P96116) (308 aa) fasta scores: E(): 4.2e-29, 35.27% id in 292 aa, and to Streptococcus pneumoniae manganese ABC transporter substrate-binding lipoprotein precursor PsaA or SP1650 SWALL:P72538 (EMBL:U53509) (309 aa) fasta scores: E(): 1.6e-19, 28.47% id in 309 aa, and to Streptococcus gordonii challis coagregation-mediating adhesin precursor ScaA SW:ADHS_STRGC () (310 aa) fasta scores: E(): 1.9e-20, 30.15% id in 315 aa. Note: Also similar to the downstream DIP0173 (333 aa) E(): 6.5e-38;56.061% identity in 330 aa overlap. Contains a twin-arginine translocation (TAT) system recognition motif (RRGFIR) at the N-terminal region NP_938562.1 Similar to Bacillus subtilis probable metal transport system ATP-binding protein YtgB SW:YTGB_BACSU (O34338) (250 aa) fasta scores: E(): 5.3e-33, 45.61% id in 228 aa, and to Streptococcus gordonii challis hypothetical ABC transporter ATP-binding protein in ScaA 5'region SW:YSC1_STRGC (P42360) (251 aa) fasta scores: E(): 4.6e-30, 40.26% id in 231 aa NP_938563.1 Similar to Bacillus subtilis probable metal transport system membrane protein YtgC SW:YTGC_BACSU (O35024) (435 aa) fasta scores: E(): 3.1e-22, 33.91% id in 286 aa, and to Treponema pallidum zinc transport system membrane protein TroC or TP0165 SW:TROC_TREPA (P96118) (298 aa) fasta scores: E(): 1.5e-21, 35.69% id in 297 aa NP_938564.1 Similar to Treponema pallidum zinc transport system membrane protein Trod or TP0166 SW:TROD_TREPA (P96119) (367 aa) fasta scores: E(): 3.4e-27, 35.97% id in 278 aa, and to Bacillus subtilis YtgD TR:O34500 (EMBL:AF008220) (295 aa) fasta scores: E(): 2.8e-25, 35.92% id in 270 aa NP_938565.1 Similar to Neisseria meningitidis periplasmic binding protein NMA0789 SWALL:Q9JVL4 (EMBL:AL162754) (308 aa) fasta scores: E(): 2.7e-24, 31.71% id in 309 aa, and to Treponema pallidum periplasmic zinc-binding protein TroA or TroMP1 or TP0163 SWALL:TROA_TREPA (SWALL:P96116) (308 aa) fasta scores: E(): 2.5e-16, 33.12% id in 317 aa, and to Streptococcus pyogenes zinc-binding protein precursor AdcA or SPY0714 SWALL:Q9A0L9 (EMBL:AE006523) (515 aa) fasta scores: E(): 2.5e-16, 28.85% id in 298 aa Note: Also similar to the upstream DIP0169, (321 aa) E(): 4.5e-38; 56.798% identity in 331 aa overlap NP_938566.1 Similar to Mycobacterium leprae ABC transporter ATP-binding component ML0114 SWALL:Q9CDA0 (EMBL:AL583917) (272 aa) fasta scores: E(): 2.3e-60, 74.4% id in 254 aa, and to Xylella fastidiosa ABC transporter ATP-binding protein XF2568 SWALL:Q9PAF0 (EMBL:AE004064) (246 aa) fasta scores: E(): 1.4e-34, 45.93% id in 246 aa NP_938567.1 Similar to Mycobacterium leprae ABC transporter component ML0112 SWALL:Q9CDA2 (EMBL:AL583917) (276 aa) fasta scores: E(): 1.2e-60, 55.23% id in 277 aa, and to Xylella fastidiosa ABC transporter permease XF2567 SWALL:Q9PAF1 (EMBL:AE004064) (267 aa) fasta scores: E(): 5.2e-37, 36.5% id in 263 aa NP_938568.1 Similar to Mycobacterium leprae hypothetical protein ML0117 TR:Q9CD97 (EMBL:AL583917) (398 aa) fasta scores: E(): 8.1e-38, 35.73% id in 417 aa NP_938569.1 Similar to Streptomyces coelicolor quinone oxidoreductase SCGD3.24c TR:Q9XA55 (EMBL:AL096822) (326 aa) fasta scores: E(): 1.4e-57, 53.87% id in 323 aa NP_938570.1 Similar to Streptomyces coelicolor histidinol-phophate aminotransferase SCD78.11 TR:Q9ZBY8 (EMBL:AL034355) (359 aa) fasta scores: E(): 6.9e-55, 49.85% id in 345 aa, and to Streptomyces tendae NikT protein TR:Q9F2E4 (EMBL:AJ250581) (440 aa) fasta scores: E(): 1.1e-42, 42.9% id in 324 aa NP_938571.1 Similar to Staphylococcus aureus subsp aureus Mu50 hypothetical 57.2 kDa protein SAV1916 TR:BAB58078 (EMBL:AP003363) (520 aa) fasta scores: E(): 3.6e-71, 41.38% id in 505 aa, and to Helicobacter pylori sodium-dependent transporter HP0214 TR:O25003 (EMBL:AE000541) (552 aa) fasta scores: E(): 9.3e-34, 50.45% id in 555 aa NP_938574.1 Similar to Mycobacterium phage MS6 Integrase Int TR:O55248 (EMBL:AF030986) (372 aa) fasta scores: E(): 1.5e-09, 26.48% id in 370 aa NP_938575.1 Similar to Streptococcus pneumoniae transcriptional regulator SP1809 TR:AAK75882 (EMBL:AE007473) (383 aa) fasta scores: E(): 8.2e-14, 29.35% id in 310 aa NP_938579.1 Similar to Pyrococcus abyssi repressor protein, PAB7155 TR:Q9V101 (EMBL:AJ248284) (73 aa) fasta scores: E(): 0.002, 36.06% id in 61 aa NP_938582.1 Similar to Staphylococcus aureus prophage phiPV83 antirepressor TR:Q9MBT0 (EMBL:AB044554) (265 aa) fasta scores: E(): 1.5e-32, 42.8% id in 257 aa NP_938584.1 No significant database matches. Possible exported protein NP_938594.1 C-terminal region similar to Bacteriophage BFK20 portal protein TR:Q9MBK2 (EMBL:AJ278322) (215 aa) fasta scores: E(): 1e-40, 56.45% id in 209 aa, and N-terminal region to Bacteriophage BFK20 hypothetical 24.1 kDa protein TR:Q9MBK3 (EMBL:AJ278322) (213 aa) fasta scores: E(): 3.8e-29, 41.79% id in 201 aa. Note: It seems these two bacterophage proteins have been fused into DIP0203 NP_938595.1 C-terminal region similar to Bacteriophage BFK20 prohead protease TR:Q9MBK0 (EMBL:AJ278322) (204 aa) fasta scores: E(): 1.1e-35, 66.46% id in 164 aa, and N-terminal region to Bacteriophage BFK20 hypothetical 18.4 kDa protein TR:Q9MBK1 (EMBL:AJ278322) (176 aa) fasta scores: E(): 6.2e-14, 51.06% id in 94 aa. Note: It seems these two bacterophage proteins have been fused into DIP0204 NP_938596.1 Similar to Bacteriophage BFK20 major capsid protein TR:Q9MBJ9 (EMBL:AJ278322) (428 aa) fasta scores: E(): 5e-66, 47.14% id in 420 aa NP_938598.1 Similar to Bacteriophage BFK20 hypothetical 19.9 kDa protein TR:Q9MBJ8 (EMBL:AJ278322) (180 aa) fasta scores: E(): 3.6e-16, 38.46% id in 156 aa NP_938600.1 Similar to Bacteriophage BFK20 hypothetical 10.2 kDa protein TR:Q9MBJ7 (EMBL:AJ278322) (94 aa) fasta scores: E(): 2.5e-07, 44.57% id in 83 aa NP_938601.1 Similar to Bacteriophage BFK20 hypothetical 13.7 kDa protein TR:Q9MBJ6 (EMBL:AJ278322) (126 aa) fasta scores: E(): 1.5e-11, 37.06% id in 116 aa NP_938602.1 N-terminal region similar to Bacteriophage BFK20 hypothetical 13.9 kDa protein TR:Q9MBJ5 (EMBL:AJ278322) (125 aa) fasta scores: E(): 1.3e-21, 50% id in 116 aa, and C-terminal region to Bacteriophage BFK20 hypothetical 14.9 kDa protein TR:Q9MBJ4 (EMBL:AJ278322) (145 aa) fasta scores: E(): 3e-10, 37.85% id in 140 aa. Note: It seems these two bacterophage proteins have been fused into DIP0210 NP_938603.1 Similar to Bacteriophage BFK20 hypothetical 15.7 kDa protein TR:Q9MBJ3 (EMBL:AJ278322) (138 aa) fasta scores: E(): 3.2e-08, 37.09% id in 124 aa NP_938605.1 C-terminal region identical to Corynephage beta immunity-specific protein Beta241 TR:Q37919 (EMBL:L04258) (241 aa) fasta scores: E(): 3.1e-64, 100% id in 241 aa, and whole length similar to Staphylococcus aureus subspaureus Mu50 phi pvl ORF15 and 16 homologue SAV1955 TR:BAB58117 (EMBL:AP003364) (1509 aa) fasta scores: E(): 2.9e-19, 23.76% id in 1073 aa NP_938606.1 Similar to the previously sequenced Corynephage beta immunity-specific protein Beta201 TR:Q37920 (EMBL:L04258) (201 aa) fasta scores: E(): 3.9e-64, 85.64% id in 202 aa. Note: there is a frameshift in the already sequenced data in from residue 167 NP_938607.1 Almost identical to previously sequenced Corynephage beta immunity-specific protein Beta286 TR:Q37921 (EMBL:L04258) (286 aa) fasta scores: E(): 1.1e-115, 99.65% id in 286 aa NP_938608.1 Almost identical to previously sequenced Corynephage beta immunity-specific protein Beta371 beta371 TR:Q37922 (EMBL:L04258) (371 aa) fasta scores: E(): 9.9e-126, 89.75% id in 371 aa NP_938609.1 Low similarity to N-terminal region of Bacteriophage lambda side tail fiber protein Stf SW:STF_LAMBD (P03764) (774 aa) fasta scores: E(): 0.0021, 24.28% id in 383 aa NP_938611.1 C-terminal region similar to C-terminal region of Mycobacteriophage TM4 GP29 TR:Q9ZX49 (EMBL:AF068845) (547 aa) fasta scores: E(): 3.7e-35, 49.14% id in 234 aa NP_938615.1 Identical to previously sequenced Corynephage beta diphtheria toxin precursor SW:DTX_CORBE (P00588) (567 aa) fasta scores: E(): 6.2e-216, 100% id in 560 aa, and to Corynephage omega diphtheria toxin precursor SW:DTX_COROM (P00587) (560 aa) fasta scores: E(): 1.1e-215, 99.82% id in 560 aa. Note: The start codon for DIP0222 is 7 residues downstream of the one in Corynephage beta NP_938618.1 N-terminal region similar to Mycobacterium tuberculosis CDC1551 polysaccharide deacetylase, MT1128 TR:AAK45386 (EMBL:AE006993) (291 aa) fasta scores: E(): 2.1e-22, 42.43% id in 205 aa NP_938619.1 Similar to Streptomyces coelicolor GntR-family regulator SC5G8.04 TR:Q9KZB0 (EMBL:AL353872) (462 aa) fasta scores: E(): 8.4e-38, 36.46% id in 458 aa NP_938620.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate NP_938621.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate NP_938624.1 Similar to Actinomyces naeslundii fimbrial associated protein TR:O05996 (EMBL:U85709) (280 aa) fasta scores: E(): 4.5e-16, 40.000% id in 215 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 1.2, 26.923% id in 156 aa. Note: Also similar to DIP0236 (312 aa) E(): 5.7e-25; 45.342% identity in 322 aa overlap, DIP2224, DIP2012 and DIP2225 NP_938626.1 Similar to Actinomyces viscosus type-1 fimbrial major subunit precursor FimP TR:Q9X4D1 (EMBL:AF106034) (535 aa) fasta scores: E(): 6.9e-16, 31.5% id in 530 aa. Note: Contains a potential sortase anchor site (LTMPG) upstream of the C-terminal region transmembrane domain NP_938627.1 Similar to Actinomyces naeslundii fimbrial associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 1.2e-31, 42.802% id in 257 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.094, 27.559% id in 127 aa. Note: Also similar to DIP0233 (329 aa) E(): 5.2e-25; 45.031% identity in 322 aa overlap. Note: Also similar to DIP2012, DIP2224 and DIP2225 NP_938628.1 No significant database matches. Note: Contains a potential sortase anchor site (LALTG) upstream of the C-terminal region transmembrane domain NP_938629.1 weak similarity to Actimomyces fimbrial associated protein. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain NP_938632.1 Similar to Burkholderia cepacia insertion element IS401 hypothetical 12.4 kDa protein SW:YISX_BURCE (Q51647) (107 aa) fasta scores: E(): 1.6e-06, 36.78% id in 87 aa NP_938634.1 No significant database matches. Possible secreted protein NP_938635.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_938636.1 Similar to Mycobacterium tuberculosis hypothetical 17.9 kDa protein Rv3753c or MTV025.10c TR:O69720 (EMBL:AL022121) (166 aa) fasta scores: E(): 1e-20, 45.57% id in 147 aa; Conserved hypothetical protein NP_938637.1 Similar to Bifidobacterium longum cytosine deaminase TR:Q9F9W7 (EMBL:AF160969) (143 aa) fasta scores: E(): 1.2e-28, 53.47% id in 144 aa, and to Mycobacterium tuberculosis CDC1551 cytidine and deoxycytidylate deaminase MT3859 TR:AAK48223 (EMBL:AE007181) (152 aa) fasta scores: E(): 6.9e-28, 53.47% id in 144 aa NP_938638.1 Similar to Arthrobacter spTM1 excisionase TR:Q9LCU5 (EMBL:AF042490) (174 aa) fasta scores: E(): 4.4e-21, 41.07% id in 168 aa NP_938639.1 Doubtful CDS. No significant database matches NP_938640.1 Similar to Streptomyces coelicolor membrane transport protein sce87.17C TR:Q9RKC1 (EMBL:AL132674) (745 aa) fasta scores: E(): 2.9e-36, 42.48% id in 798 aa NP_938641.1 Similar to Archaeoglobus fulgidus queuine tRNA-ribosyltransferase Tgt or AF1485 SW:TGT_ARCFU (O28787) (403 aa) fasta scores: E(): 8.6e-40, 40.78% id in 407 aa, and to Escherichia coli queuine tRNA-ribosyltransferase Tgt or B0406 or Z0505 or ECS0457 SW:TGT_ECOLI (P19675) (375 aa) fasta scores: E(): 4.5e-13, 37.68% id in 406 aa NP_938642.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu NP_938643.1 Similar to Corynebacterium glutamicum gluconate permease GntP TR:Q9AL75 (EMBL:AJ296014) (463 aa) fasta scores: E(): 2.9e-113, 69.34% id in 460 aa, and to Bacillus subtilis gluconate permease GntP SW:GNTP_BACSU (P12012) (448 aa) fasta scores: E(): 4.8e-53, 38.58% id in 451 aa NP_938644.1 Similar to Streptomyces coelicolor gluconokinase SCI52.21 TR:Q9AD88 (EMBL:AL590507) (175 aa) fasta scores: E(): 4.2e-33, 60.39% id in 154 aa, and to Escherichia coli thermosensitive gluconokinase IdnK or GntV or B4268 SW:IDNK_ECOLI (P39208) (187 aa) fasta scores: E(): 3e-20, 44.15% id in 154 aa NP_938645.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938646.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938647.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3825 TR:AAK48194 (EMBL:AE007179) (435 aa) fasta scores: E(): 5.2e-94, 55.95% id in 420 aa NP_938649.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_938650.1 Similar to Mycobacterium tuberculosis protein Rv3716c or MT3819 or MTV025.064c SW:Y1B6_MYCTU (O69683) (133 aa) fasta scores: E(): 2.7e-14, 54.16% id in 96 aa NP_938651.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_938652.1 Similar to Mycobacterium tuberculosis CDC1551 cobyric acid synthase MT3816 TR:AAK48185 (EMBL:AE007178) (231 aa) fasta scores: E(): 1.3e-31, 58.13% id in 246 aa, and to Streptomyces coelicolor hypothetical 26.2 kDa protein 2SCG58.13 TR:Q9FCA0 (EMBL:AL391017) (242 aa) fasta scores: E(): 6.6e-20, 42.85% id in 252 aa NP_938653.1 Similar to Mycobacterium tuberculosis hypothetical 43.4 kDa protein Rv3712 or MTV025.060 TR:O69679 (EMBL:AL022121) (413 aa) fasta scores: E(): 2.3e-86, 59.95% id in 412 aa, and to Streptomyces coelicolor ligase 2SCG58.12 TR:Q9FCA1 (EMBL:AL391017) (412 aa) fasta scores: E(): 4.3e-59, 43.03% id in 409 aa NP_938654.1 3'-5' exonuclease of DNA polymerase III NP_938655.1 Similar to Escherichia coli oxygen-insensitive NADPH nitroreductase NfsA or MdaA or Mda18 or B0851 SW:NFSA_ECOLI (P17117) (240 aa) fasta scores: E(): 2e-23, 36.32% id in 223 aa NP_938656.2 Similar to Corynebacterium glutamicum 2-isopropylmalate synthase LeuA SW:LEU1_CORGL (P42455) (616 aa) fasta scores: E(): 2.5e-205, 83.27% id in 604 aa NP_938657.1 Similar to Bacillus subtilis deoxyribonucleoside regulator DeoR SW:DEOR_BACSU (P39140) (313 aa) fasta scores: E(): 6.6e-43, 42.9% id in 303 aa NP_938658.1 C-terminal region similar to C-terminal region of Mycobacterium tuberculosis hypothetical 58.9 kDa protein Rv2100 precursor or MT2160 or MTCY49.40 SW:YL00_MYCTU (Q10709) (550 aa) fasta scores: E(): 7.5e-09, 35.11% id in 131 aa NP_938659.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate NP_938660.1 Similar to Staphylococcus aureus SA0132 protein TR:Q99X78 (EMBL:AP003129) (450 aa) fasta scores: E(): 3.5e-67, 46.1% id in 436 aa, and to Bacillus subtilis tetracycline resistance protein TetB or Tet SW:TCRB_BACSU (P23054) (458 aa) fasta scores: E(): 1.3e-23, 26.3% id in 403 aa NP_938661.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate NP_938662.1 Similar to Streptomyces coelicolor phosphomannomutase SCK13.08c TR:Q9AD82 (EMBL:AL512667) (549 aa) fasta scores: E(): 7.9e-86, 46.75% id in 554 aa NP_938663.1 Similar to Streptomyces coelicolor integral membrane protein 2SCI34.05 TR:Q9EWX4 (EMBL:AL445403) (396 aa) fasta scores: E(): 1.3e-08, 28.77% id in 358 aa NP_938664.1 Similar to Corynebacterium glutamicum hypothetical 29.6 kDa protein in leuA-lysC intergenic region SW:YLEU_CORGL (P42459) (270 aa) fasta scores: E(): 4.6e-47, 58.18% id in 220 aa NP_938665.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. NP_938666.1 Low similarity to Staphylococcus aureus Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein SdrE or SAV0563 TR:BAB56725 (EMBL:AP003359) (1141 aa) fasta scores: E(): 1.9e-05, 21.85% id in 668 aa. Note: Contains a potential sortase anchor site (LARTG) upstream of the C-terminal region transmembrane domain NP_938667.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_938668.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription NP_938669.1 Similar to Onchocerca volvulus endobacterium catalase Cat SW:CATA_ONCVE (Q27710) (482 aa) fasta scores: E(): 8e-92, 52.24% id in 490 aa NP_938670.1 Similar to Vibrio cholerae iron (III) ABC transporter, ATP-binding protein VC0610 TR:Q9KUB3 (EMBL:AE004146) (343 aa) fasta scores: E(): 7e-18, 34.743% id in 331 aa, and to Archaeoglobus fulgidus branched-chain amino acid ABC transporter, ATP-binding protein AF0221 TR:O30018 (EMBL:AE001090) (224 aa) fasta scores: E(): 9.2e-17, 34.562% id in 217 aa NP_938671.1 Similar to Treponema hyodysenteriae permease ShiD TR:O54371 (EMBL:U75349) (277 aa) fasta scores: E(): 0.0013, 21.739% id in 184 aa, and to Escherichia coli O157:H7 EDL933 transport system permease YabK TR:AAG54371 (EMBL:AE005183) (536 aa) fasta scores: E(): 0.019, 21.995% id in 441 aa NP_938672.1 Similar to Escherichia coli O157:H7 periplasmic-iron-binding protein ECS0415 TR:BAB33838 (EMBL:AP002551) (343 aa) fasta scores: E(): 5.5e-19, 27.139% id in 339 aa, and to Actinobacillus pleuropneumoniae AfuA protein TR:Q57512 (EMBL:U05042) (346 aa) fasta scores: E(): 4.2e-16, 26.280% id in 293 aa, and to Serratia marcescens iron(III)-binding periplasmic protein precursor SfuA SW:SFUA_SERMA (P21408) (338 aa) fasta scores: E(): 0.00026, 20.000% id in 290 aa NP_938673.1 Similar to Bacillus subtilis glycerol-3-phosphate transporter GlpT SW:GLPT_BACSU (P37948) (444 aa) fasta scores: E(): 1.4e-74, 45.434% id in 438 aa, and to Escherichia coli glycerol-3-phosphate transporter GlpT or B2240 SW:GLPT_ECOLI (P08194) (452 aa) fasta scores: E(): 4.2e-74, 44.295% id in 447 aa NP_938674.1 Similar to Klebsiella pneumoniae phosphate regulon transcriptional regulatory protein PhoB SW:PHOB_KLEPN (P45605) (229 aa) fasta scores: E(): 1.7e-25, 40.708% id in 226 aa, to Shigella dysenteriae phosphate regulon transcriptional regulatory protein PhoB SW:PHOB_SHIDY (P45606) (229 aa) fasta scores: E(): 6.5e-25, 40.265% id in 226 aa, and to Escherichia coli phosphate regulon transcriptional regulatory protein PhoB or B0399 or Z0497 or ECS0449 SW:PHOB_ECOLI (P08402) (229 aa) fasta scores: E(): 6.5e-25, 40.265% id in 226 aa NP_938675.1 Similar to Escherichia coli sensor protein RcsC or B2218 SW:RCSC_ECOLI (P14376) (933 aa) fasta scores: E(): 5.5e-10, 26.339% id in 224 aa, and to Pseudomonas syringae sensor protein GacS or LemA SW:GACS_PSESY (P48027) (907 aa) fasta scores: E(): 2e-09, 27.530% id in 247 aa NP_938676.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport NP_938677.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_938678.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_938679.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone NP_938680.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_938681.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_938682.1 Similar to Deinococcus radiodurans conserved hypothetical protein DR0075 TR:Q9RY75 (EMBL:AE001870) (1467 aa) fasta scores: E(): 3e-06, 27.568% id in 370 aa NP_938684.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3785 TR:AAK48152 (EMBL:AE007176) (319 aa) fasta scores: E(): 1.6e-59, 54.08% id in 294 aa NP_938685.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3790 TR:AAK48157 (EMBL:AE007176) (154 aa) fasta scores: E(): 2e-23, 57.14% id in 154 aa NP_938686.1 Similar to Mycobacterium leprae Pbp1 Pon1 SWALL:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 4.9e-130, 48.08% id in 757 aa, and to Mycobacterium tuberculosis CDC1551 penicillin-binding protein 1 MT3784 TR:AAK48151 (EMBL:AE007176) (810 aa) fasta scores: E(): 4.8e-134, 48.75% id in 761 aa NP_938687.1 Similar to Mycobacterium tuberculosis regulatory protein Rv681c or MTV025.029c TR:O69649 (EMBL:AL022121) (100 aa) fasta scores: E(): 4.9e-22, 65.06% id in 83 aa, and to Mycobacterium tuberculosis CDC1551 WhiB-related protein MT3783 TR:AAK48150 (EMBL:AE007176) (118 aa) fasta scores: E(): 5.6e-22, 65.06% id in 83 aa NP_938688.1 Similar to Streptomyces coelicolor hypothetical 6.1 kDa protein SCH17.10c TR:Q9XA37 (EMBL:AL079353) (53 aa) fasta scores: E(): 5.4e-16, 85.71% id in 49 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3780 TR:AAK48147 (EMBL:AE007175) (53 aa) fasta scores: E(): 5.9e-14, 77.08% id in 48 aa NP_938689.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3779 TR:AAK48146 (EMBL:AE007175) (151 aa) fasta scores: E(): 1.3e-30, 63.75% id in 149 aa, and to Streptomyces coelicolor hypothetical 15.7 kDa protein SCH17.09c TR:Q9XA38 (EMBL:AL079353) (155 aa) fasta scores: E(): 2.5e-29, 62.25% id in 151 aa NP_938690.1 Similar to Mycobacterium tuberculosis hydrolase Rv3677c or MTV025.025c TR:O69645 (EMBL:AL022121) (264 aa) fasta scores: E(): 1.1e-18, 40.89% id in 269 aa NP_938691.1 Similar to Corynebacterium glutamicum probable transcription regulator TR:AAK58838 (EMBL:AF293334) (227 aa) fasta scores: E(): 8e-79, 91.18% id in 227 aa, and to Escherichia coli catabolite gene activator Crp or Cap or Csm or B3357 or Z4718 or ECS4208 SW:CRP_ECOLI (P03020) (210 aa) fasta scores: E(): 4.6e-15, 33.68% id in 190 aa NP_938692.1 Similar to Mycobacterium tuberculosis endonuclease III Nth or Rv3674c or MT3775 or MTV025.022c SW:END3_MYCTU (O69642) (245 aa) fasta scores: E(): 2.2e-59, 62.04% id in 245 aa, and to Bacillus subtilis probable endonuclease III Nth or JooB SW:END3_BACSU (P39788) (219 aa) fasta scores: E(): 1.4e-28, 41.96% id in 193 aa NP_938693.1 Similar to Mycobacterium tuberculosis CDC1551 thioredoxin-related protein MT3774 TR:AAK48141 (EMBL:AE007175) (227 aa) fasta scores: E(): 7.6e-13, 32.84% id in 204 aa NP_938694.1 Similar to Streptomyces coelicolor hypothetical 26.5 kDa protein SCH17.02c TR:Q9XA45 (EMBL:AL079353) (247 aa) fasta scores: E(): 1.9e-26, 40.08% id in 227 aa NP_938695.1 Similar to Mycobacterium tuberculosis CDC1551 serine protease MT3772 TR:AAK48139 (EMBL:AE007175) (397 aa) fasta scores: E(): 1.5e-47, 38.19% id in 398 aa NP_938696.1 Similar to Streptomyces coelicolor hydrolase SCH5.29 TR:Q9X931 (EMBL:AL035636) (324 aa) fasta scores: E(): 5.8e-17, 31.21% id in 330 aa NP_938697.1 Similar to Mycobacterium tuberculosis hypothetical 18.9 kDa protein Rv3669 or MTV025.017 TR:O69637 (EMBL:AL022121) (172 aa) fasta scores: E(): 1.8e-20, 51.85% id in 135 aa NP_938698.1 Similar to Mycobacterium tuberculosis hypothetical 26.4 kDa protein Rv3662c or MTV025.010c TR:O69630 (EMBL:AL022121) (256 aa) fasta scores: E(): 3.1e-07, 31.44% id in 229 aa NP_938699.1 Similar to Mycobacterium tuberculosis hypothetical 30.7 kDa protein Rv3661 or MT3761 or MTV025.009 SW:Y0G1_MYCTU (O69629) (287 aa) fasta scores: E(): 2.2e-40, 45.22% id in 272 aa, and to Streptomyces coelicolor morphological differentiation-associated protein SCH5.21 TR:Q9X923 (EMBL:AL035636) (268 aa) fasta scores: E(): 5e-38, 45.8% id in 262 aa NP_938700.1 Similar to Mycobacterium tuberculosis hypothetical 35.8 kDa protein Rv3660c or MT3760 or MTV25.008c TR:O69628 (EMBL:AL022121) (350 aa) fasta scores: E(): 9.7e-19, 30.29% id in 340 aa, and to Streptomyces cyaneus (Streptomyces curacoi) inhibition of morphological differentiation TR:O33612 (EMBL:AB004855) (370 aa) fasta scores: E(): 1.6e-13, 33.08% id in 266 aa NP_938701.1 Similar to Mycobacterium tuberculosis hypothetical 36.7 kDa protein Rv3659c or MTV025.007c TR:O69627 (EMBL:AL022121) (352 aa) fasta scores: E(): 6.7e-51, 52.21% id in 316 aa NP_938702.1 Similar to Mycobacterium tuberculosis transmembrane protein Rv3658c or MTV025.006c TR:O69626 (EMBL:AL022121) (266 aa) fasta scores: E(): 6.1e-17, 36.52% id in 230 aa NP_938703.1 Similar to Mycobacterium tuberculosis hypothetical 19.1 kDa protein Rv3657c or MTV025.005c TR:O69625 (EMBL:AL022121) (191 aa) fasta scores: E(): 2.9e-10, 36.66% id in 150 aa NP_938704.1 Similar to Mycobacterium tuberculosis hypothetical 7.1 kDa protein Rv3656c or MTV025.004c TR:O69624 (EMBL:AL022121) (68 aa) fasta scores: E(): 2.6e-05, 43.33% id in 60 aa NP_938705.1 Similar to Mycobacterium tuberculosis hypothetical 13.0 kDa protein Rv3655c or MTV025.003c TR:O69623 (EMBL:AL022121) (125 aa) fasta scores: E(): 1.4, 31.81% id in 66 aa NP_938706.1 Similar to the central region of Streptomyces coelicolor membrane spanning protein SCH5.14c TR:Q9X916 (EMBL:AL035636) (230 aa) fasta scores: E(): 2.6e-05, 35.23% id in 105 aa NP_938707.1 Similar to Mycobacterium tuberculosis CDC1551 ATP-dependent RNA helicase, DeaD/DeaH box family MT3751 TR:AAK48112 (EMBL:AE007173) (771 aa) fasta scores: E(): 1.3e-152, 54.73% id in 760 aa, and to Bacillus subtilis helicase YprA SW:YPRA_BACSU (P50830) (749 aa) fasta scores: E(): 4.7e-67, 34.86% id in 763 aa NP_938708.1 Similar to Mycobacterium smegmatis cold-shock protein CspA TR:Q9KGW0 (EMBL:AF281675) (67 aa) fasta scores: E(): 5.8e-23, 86.56% id in 67 aa NP_938709.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding protein SC4A2.02c TR:O86658 (EMBL:AL031182) (229 aa) fasta scores: E(): 6.7e-12, 39.3% id in 201 aa NP_938710.1 Similar to Escherichia coli hypothetical ABC transporter ATP-binding protein YddO or B1483 SW:YDDO_ECOLI (P77622) (308 aa) fasta scores: E(): 1.7e-15, 36.36% id in 209 aa NP_938711.1 Similar to Streptomyces coelicolor transport system permease sc4g2.20 TR:O86692 (EMBL:AL031371) (436 aa) fasta scores: E(): 4.5e-47, 42.61% id in 406 aa NP_938712.1 Similar to Streptomyces coelicolor solute-binding lipoprotein SC4G2.18 TR:O86690 (EMBL:AL031371) (503 aa) fasta scores: E(): 1.3e-64, 39.63% id in 497 aa NP_938713.1 Similar to Streptomyces coelicolor transport system permease SC4G2.19 TR:O86691 (EMBL:AL031371) (601 aa) fasta scores: E(): 1.9e-62, 37.01% id in 570 aa NP_938714.1 Similar to Streptomyces coelicolor oxidoreductase SCF43A.31 TR:Q9XA84 (EMBL:AL096837) (520 aa) fasta scores: E(): 7.8e-84, 44.21% id in 484 aa NP_938715.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_938716.1 Similar to Streptococcus pneumoniae Pap2 family protein SP0489 TR:AAK74647 (EMBL:AE007360) (216 aa) fasta scores: E(): 2.3e-06, 30.43% id in 207 aa NP_938717.1 Similar to Mycobacterium tuberculosis CDC1551 opt family protein MT2465 TR:AAK46760 (EMBL:AE007086) (667 aa) fasta scores: E(): 3.6e-138, 61.18% id in 644 aa NP_938718.1 C-terminal region similar to Micromonospora viridifaciens sialidase precursor NedA SW:NANH_MICVI (Q02834) (647 aa) fasta scores: E(): 1.8e-23, 34.24% id in 403 aa NP_938719.1 Similar to Klebsiella oxytoca YiaX1 TR:AAK69523 (EMBL:AF282849) (315 aa) fasta scores: E(): 4.4e-18, 31.94% id in 313 aa NP_938720.1 Similar to Mycobacterium tuberculosis CDC1551 adenylate cyclase, MT3748 TR:AAK48108 (EMBL:AE007173) (549 aa) fasta scores: E(): 5.4e-73, 42.99% id in 507 aa NP_938721.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_938724.1 Similar to Mycobacterium tuberculosis hypothetical 8.5 kDa protein Rv1055 or MTV017.08 TR:O53403 (EMBL:AL021897) (78 aa) fasta scores: E(): 0.00013, 45.16% id in 62 aa NP_938725.1 Low similarity to bacteriophage BIL309 Integrase Int TR:Q9AZR0 (EMBL:AF323670) (377 aa) fasta scores: E(): 0.45, 27.41% id in 124 aa NP_938731.1 Similar to Escherichia coli transposase InsI for insertion sequence element IS30B/C/D (InsI1 or B0256) and (InsI2 or B1404) and (InsI3 or B4284) SW:INSI_ECOLI (P37246) (383 aa) fasta scores: E(): 0.72, 45.45% id in 44 aa NP_938733.1 Similar to Neisseria meningitidis hypothetical protein NMB0459 TR:Q9K0V1 (EMBL:AE002402) (369 aa) fasta scores: E(): 1.8e-58, 45.47% id in 365 aa NP_938734.1 Similar to Streptomyces coelicolor DNA repair protein SCG20A.20c TR:Q9K3M0 (EMBL:AL360055) (216 aa) fasta scores: E(): 1.4e-27, 44.54% id in 220 aa, and to Escherichia coli alkylated DNA repair protein AlkB or AidD or B2212 SW:ALKB_ECOLI (P05050) (216 aa) fasta scores: E(): 5.6e-10, 32.46% id in 231 aa NP_938735.1 Similar to Streptomyces coelicolor hydrolase SCBAC14E8.01c TR:Q9ADJ8 (EMBL:AL590435) (228 aa) fasta scores: E(): 1.6e-05, 28.49% id in 186 aa NP_938736.1 Low similarity to central part of Corynebacterium glutamicum replicase RepA TR:Q9EUN5 (EMBL:AF164956) (479 aa) fasta scores: E(): 1.8e-16, 56.86% id in 102 aa NP_938737.1 Similar to Clostridium perfringens hypothetical 6.1 kDa protein SW:YPI8_CLOPE (P18018) (55 aa) fasta scores: E(): 1, 42.85% id in 35 aa NP_938738.1 Similar to N-terminal region of Streptococcus pneumoniae 3-hydroxy-3-methylglutaryl-CoA reductase SP1726 TR:AAK75803 (EMBL:AE007465) (424 aa) fasta scores: E(): 8.7, 26.38% id in 144 aa NP_938740.1 C-terminal region Similar to Deinococcus radiodurans alpha-dextran endo-1,6-alpha-glucosidase DR0405 TR:Q9RXB0 (EMBL:AE001900) (910 aa) fasta scores: E(): 3.1e-110, 41.4% id in 942 aa, and N-terminal region similar to Streptomyces lividans alpha-amylase precursor Amy SW:AMY_STRLI (Q05884) (919 aa) fasta scores: E(): 1.4e-86, 41.56% id in 676 aa NP_938741.1 activates fatty acids by binding to coenzyme A NP_938742.1 Low similarity to Streptomyces scabies esterase precursor EstA SW:ESTA_STRSC (P22266) (345 aa) fasta scores: E(): 0.12, 26.28% id in 331 aa NP_938743.1 Similar to Escherichia coli glucose-1-phosphate thymidylyltransferase RfbA SW:RBA2_ECOLI (P55253) (293 aa) fasta scores: E(): 1.5e-64, 59.93% id in 287 aa NP_938744.1 N-terminal region similar to Streptococcus pneumoniae dTDP-4-keto-6-deoxyglucose-3,5-epimerase CPS19AM TR:Q9Z642 (EMBL:AF105113) (197 aa) fasta scores: E(): 2.5e-29, 51.68% id in 178 aa, and C-terminal region to Serratia marcescens dTDP-L-rhamnose synthase RmlD TR:O52480 (EMBL:AF038816) (288 aa) fasta scores: E(): 6.7e-28, 38.79% id in 281 aa NP_938745.1 Similar to Mycobacterium leprae dTDP-(glucose or rhamnose)-4,6-dehydratase RmlB TR:Q9X7A3 (EMBL:AL049491) (331 aa) fasta scores: E(): 8.3e-84, 63.77% id in 334 aa NP_938746.1 Similar to Streptomyces coelicolor metallopeptidase SCD95A.06c TR:Q9KXW8 (EMBL:AL357432) (473 aa) fasta scores: E(): 5.2e-42, 32.16% id in 457 aa NP_938747.1 Similar to Mycobacterium tuberculosis CDC1551 prolyl oligopeptidase MT0473 TR:AAK44697 (EMBL:AE006950) (673 aa) fasta scores: E(): 9.6e-118, 46.64% id in 671 aa NP_938748.1 Similar to Corynebacterium ammoniagenes surface layer protein A SlpA TR:BAB62413 (EMBL:AB055224) (358 aa) fasta scores: E(): 1.4e-69, 52.76% id in 362 aa, and to Mycobacterium tuberculosis antigen 85-A precursor FbpA or MPT44 or Rv3804c or MT3911 or MTV026.09c SW:A85A_MYCTU (P17944) (338 aa) fasta scores: E(): 9.7e-18, 31.56% id in 320 aa NP_938749.1 Doubtful CDS. No significant database matches NP_938751.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component NP_938752.1 Similar to Mycobacterium tuberculosis CDC1551 DNA-binding protein, MT0481 TR:AAK44705 (EMBL:AE006950) (474 aa) fasta scores: E(): 2.8e-101, 55.34% id in 477 aa NP_938753.1 Low similarity to Bacillus pseudofirmus succinate dehydrogenease cytochrome B-558 subunit DhsC SWALL:O54447 (EMBL:U91843) (159 aa) fasta scores: E(): 0.011, 28.22% id in 163 aa, and to Streptomyces coelicolor cytochrome B subunit SCM10.12c TR:Q9RCY6 (EMBL:AL133469) (243 aa) fasta scores: E(): 1.8e-18, 36.01% id in 236 aa NP_938754.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_938755.1 catalyzes the reversible formation of fumarate and ubiquinol from succinate and ubiquinone NP_938758.1 Similar to Mycobacterium tuberculosis membrane protein Rv0473 or MTV038.17 TR:O53758 (EMBL:AL021933) (456 aa) fasta scores: E(): 2.5e-69, 44.47% id in 416 aa NP_938759.1 Similar to Streptomyces coelicolor membrane protein 2SCD46.14 TR:Q9FCG9 (EMBL:AL391406) (113 aa) fasta scores: E(): 0.0064, 32.14% id in 84 aa NP_938762.1 Similar to Clostridium pasteurianum pyruvate formate-lyase ativating enzyme Act SW:PFLA_CLOPA (Q46267) (238 aa) fasta scores: E(): 1.4e-32, 44.24% id in 226 aa, and to Escherichia coli pyruvate formate-lyase 1 activating enzyme PflA or Act or B0902 or Z1246 or ECS0985 SW:PFLA_ECOLI (P09374) (245 aa) fasta scores: E(): 1.1e-31, 38.68% id in 243 aa NP_938763.1 Similar to Streptomyces coelicolor hypothetical 29.8 kDa protein 2SCD46.17c TR:Q9FCG6 (EMBL:AL391406) (271 aa) fasta scores: E(): 3e-26, 47.92% id in 265 aa NP_938764.1 Low similarity to Mycobacterium tuberculosis hypothetical 19.1 kDa protein Rv0481c or MT0499 or MTCY20G9.07c SW:Y481_MYCTU (Q11147) (174 aa) fasta scores: E(): 0.028, 23.92% id in 163 aa NP_938765.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_938766.1 Similar to Bacillus subtilis YjqA protein TR:O34593 (EMBL:Z99110) (125 aa) fasta scores: E(): 5e-11, 35.51% id in 107 aa NP_938767.1 activates fatty acids by binding to coenzyme A NP_938768.1 activates fatty acids by binding to coenzyme A NP_938769.1 Similar to Streptomyces coelicolor glycosyl transferase GlgA TR:Q9X9U5 (EMBL:AJ243803) (387 aa) fasta scores: E(): 3.5e-19, 29.88% id in 415 aa and to Mycobacterium leprae hypothetical 45.3 kDa protein ML2443 or U2168f or B2168_c2_201 SW:Y486_MYCLE (P54138) (428 aa) fasta scores: E(): 1.3e-73, 52.23% id in 402 aa NP_938770.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_938771.1 Similar to Mycobacterium tuberculosis sensor-like histidine kinase SenX3 or Rv0490 or MT0509 or MTCY20G9.16 SW:SEX3_MYCTU (Q11155) (410 aa) fasta scores: E(): 3.6e-60, 48.84% id in 389 aa NP_938772.1 Similar to Mycobacterium tuberculosis sensory transduction protein RegX3 or Rv0491 or MT0510 or MTCY20G9.17 SW:RGX3_MYCTU (Q11156) (227 aa) fasta scores: E(): 4e-68, 80.97% id in 226 aa NP_938773.1 Similar to Mycobacterium tuberculosis hypothetical 32.9 kDa protein Rv0495c or MT0515 or MTCY20G9.21c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 3.6e-25, 44.07% id in 270 aa NP_938775.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_938776.1 Similar to Mycobacterium leprae B2168_C1_172 ML2429 TR:Q49828 (EMBL:U00018) (86 aa) fasta scores: E(): 7.6e-16, 80% id in 55 aa NP_938777.1 Similar to Mycobacterium tuberculosis and Mycobacterium leprae hypothetical 4.1 kDa protein Rv0500.1/ML2428.1 or Rv0500B or MT0521.1 or ML2428.1 or ML2428A SW:Y50A_MYCTU (Q9CB56) (33 aa) fasta scores: E(): 1.6e-08, 100% id in 33 aa NP_938778.1 Similar to Streptomyces coelicolor membrane protein SCBAC16H6.28 TR:CAC44607 (EMBL:AL596162) (270 aa) fasta scores: E(): 4.9e-22, 39.13% id in 207 aa NP_938779.1 Similar to Mycobacterium tuberculosis hypothetical 32.7 kDa protein Rv0505c or MT0526 or MTCY20G9.32c SW:Y505_MYCTU (Q11169) (308 aa) fasta scores: E(): 4.7e-52, 59.67% id in 243 aa NP_938780.1 Similar to Mycobacterium tuberculosis hypothetical 10.7 kDa protein Rv0508 or MT0529 or MTCY20G9.35 SW:Y508_MYCTU (Q11172) (97 aa) fasta scores: E(): 2.7e-08, 40.74% id in 81 aa NP_938781.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_938782.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_938783.1 Similar to Mycobacterium leprae possible uroporphyrin-III C-methyltransferase HemD or ML2420 TR:Q9CB60 (EMBL:AL583925) (563 aa) fasta scores: E(): 9.3e-91, 52.81% id in 551 aa NP_938784.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_938786.1 Similar to Mycobacterium tuberculosis probable cation-transporting ATPase V CtpV or Rv0969 or MT0997 or MTCY10D7.05c SW:CTPV_MYCTU (P77894) (770 aa) fasta scores: E(): 4.5e-29, 27.6% id in 797 aa NP_938787.1 Low similarity to Bacillus halodurans BH0756 protein TR:Q9KEU3 (EMBL:AP001509) (410 aa) fasta scores: E(): 1.4e-07, 23.95% id in 405 aa NP_938788.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_938789.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX NP_938790.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_938791.1 Similar to Streptomyces coelicolor phosphoglycerate mutase SCD65.13 TR:Q9F2R9 (EMBL:AL392176) (233 aa) fasta scores: E(): 1.5e-35, 50.25% id in 199 aa and low similarity to Escherichia coli probable phosphoglycerate mutase 2 GpmB or B4395 or Z5997 or ECS5353 SW:PMG2_ECOLI (P36942) (215 aa) fasta scores: E(): 8.5e-06, 25.96% id in 181 aa NP_938792.1 Similar to Deinococcus radiodurans thiol:disulfide interchange protein DR0189 TR:Q9RXW6 (EMBL:AE001881) (185 aa) fasta scores: E(): 7.1e-09, 34.84% id in 132 aa, and to Bacillus halodurans thioredoxin BH1522 TR:Q9KCP7 (EMBL:AP001512) (177 aa) fasta scores: E(): 3.4e-08, 34.12% id in 126 aa and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0548 TR:AAK44771 (EMBL:AE006954) (216 aa) fasta scores: E(): 9.2e-31, 48.95% id in 192 aa NP_938793.1 Similar to Mycobacterium leprae B2168_C1_192 ML2411 TR:Q49810 (EMBL:U00018) (262 aa) fasta scores: E(): 8.6e-46, 53.2% id in 250 aa NP_938794.1 Similar to Mycobacterium tuberculosis hypothetical 57.1 kDa protein Rv0528 or MTCY25D10.07 TR:O06394 (EMBL:Z95558) (529 aa) fasta scores: E(): 3.9e-103, 49.43% id in 532 aa NP_938795.1 Similar to Mycobacterium tuberculosis CDC1551 cytochrome C assembly family protein MT0551 TR:AAK44774 (EMBL:AE006954) (324 aa) fasta scores: E(): 6.3e-54, 47.81% id in 320 aa NP_938796.1 Similar to Streptomyces coelicolor ArsR-family transcriptional regulator SC4A9.07 TR:Q9L1V5 (EMBL:AL138668) (117 aa) fasta scores: E(): 7.2e-10, 44.57% id in 83 aa, and to Methanococcus jannaschii hypothetical protein MJ1325 TR:Q58721 (EMBL:U67573) (89 aa) fasta scores: E(): 5.1e-09, 42.16% id in 83 aa NP_938797.1 Low similarity to Mycobacterium tuberculosis CDC1551 hypothetical 6.1 kDa protein MT0553 TR:AAK44776 (EMBL:AE006954) (53 aa) fasta scores: E(): 4, 34.04% id in 47 aa NP_938798.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0554 TR:AAK44777 (EMBL:AE006954) (105 aa) fasta scores: E(): 3.1e-05, 35.8% id in 81 aa NP_938799.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_938800.1 Low similarity in parts to Mycobacterium tuberculosis hypothetical 58.9 kDa protein precursor Rv2100 or MT2160 or MTCY49.40 SW:YL00_MYCTU (Q10709) (550 aa) fasta scores: E(): 1.7e-06, 32.57% id in 132 aa NP_938801.1 Similar to Mycobacterium leprae O-succinylbenzoic acid-CoA ligase MenE or ML2257 TR:Q9CBB8 (EMBL:AL583924) (368 aa) fasta scores: E(): 7.1e-41, 43.71% id in 366 aa, and to Escherichia coli O-succinylbenzoic acid--CoA ligase MenE or B2260 SW:MENE_ECOLI (P37353) (451 aa) fasta scores: E(): 8.2e-14, 29.28% id in 379 aa NP_938802.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_938803.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate NP_938804.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis NP_938805.1 Similar to Mycobacterium tuberculosis hypothetical 18.7 kDa protein Rv0556 or MTCY25D10.35 TR:O06422 (EMBL:Z95558) (171 aa) fasta scores: E(): 1.2e-11, 42.14% id in 121 aa NP_938806.1 Similar to Agrobacterium tumefaciens Agr_C_4173p TR:AAK88039 (EMBL:AE008145) (363 aa) fasta scores: E(): 1.9e-22, 31.8% id in 305 aa NP_938807.2 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_938808.1 Similar to Clostridium acetobutylicum lactate dehydrogenase CAC3552 TR:AAK81477 (EMBL:AE007851) (320 aa) fasta scores: E(): 1.6e-36, 38.6% id in 316 aa, and to Bacillus subtilis L-lactate dehydrogenase Ldh or LctE SW:LDH_BACSU (P13714) (320 aa) fasta scores: E(): 2.9e-25, 33.95% id in 324 aa NP_938809.1 Similar to Mycobacterium leprae FAD-linked oxidoreductase ML2276 TR:Q9CBA6 (EMBL:AL583925) (408 aa) fasta scores: E(): 7.2e-61, 54.47% id in 391 aa NP_938810.1 Similar to Mycobacterium leprae polyprenyl diphosphate synthase component ML2277 TR:Q9CBA5 (EMBL:AL583925) (330 aa) fasta scores: E(): 1.6e-57, 51.69% id in 325 aa, and to Bacillus stearothermophilus heptaprenyl diphosphate synthase component II HepT or HepS-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 9.6e-33, 38.99% id in 318 aa NP_938811.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_938812.1 Modulates Rho-dependent transcription termination NP_938813.1 binds directly to 23S ribosomal RNA NP_938814.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_938815.1 Similar to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 1.3e-42, 44.48% id in 263 aa. Identical to DIP1517, DIP1526, DIP1809 and DIP2123 NP_938816.1 Similar to Streptococcus pneumoniae hypothetical 20.7 kDa protein TR:Q9KK22 (EMBL:AF154034) (171 aa) fasta scores: E(): 1.1e-07, 32.69% id in 156 aa, and to Yersinia pestis insertion element IS1661 DNA-binding protein YPO4046 TR:CAC93502 (EMBL:AJ414160) (171 aa) fasta scores: E(): 0.00096, 26.06% id in 165 aa. Identical to DIP1518, DIP1525, DIP1808 and DIP2124 NP_938817.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_938818.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_938819.1 C-terminal similar to Bacillus halodurans surface adhesin A precursor PsaA or BH0516 TR:Q9KFG3 (EMBL:AP001508) (300 aa) fasta scores: E(): 2.9e-14, 34.09% id in 176 aa NP_938820.1 No significant database matches. Note: Also presents similarities with DIP1724, DIP0442, DIP2325 and DIP0443 NP_938821.1 Similar to Deinococcus radiodurans manganese ABC transporter, ATP-binding protein, DR2284 TR:Q9RS43 (EMBL:AE002060) (239 aa) fasta scores: E(): 5.3e-25, 39.57% id in 235 aa NP_938822.1 Similar to Streptococcus gordonii challis 29 kDa membrane protein in psaA 5'region SW:P29K_STRGC (P42361) (278 aa) fasta scores: E(): 3.8e-28, 38.25% id in 264 aa NP_938823.1 No significant database matches. Note: Also similar to DIP0439, DIP1724, DIP2325 and DIP0443 NP_938824.1 No significant database matches. Note: Contains a potential sortase anchor site (LPDTG) upstream of the C-terminal region transmembrane domain. Also similar to DIP0439, DIP1724, DIP0442 and DIP2325 NP_938825.1 No significant database matches. Contains a lysine rich region close to the C-terminal end NP_938826.1 Low similarity to Mycobacterium leprae integral membrane protein ML2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 2.5, 24.7% id in 344 aa NP_938827.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_938828.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_938829.1 Similar to Streptomyces coelicolor ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 2.4e-29, 44.49% id in 236 aa NP_938830.1 Low similarity to Staphylococcus aureus, ABC transporter VraE or SA2493 or SAV2702 TR:Q9KWJ6 (EMBL:AB035452) (626 aa) fasta scores: E(): 0.066, 21.03% id in 385 aa NP_938833.1 Low similarity to Corynebacterium jeikeium transposase A TnpA TR:AAK67709 (EMBL:AY036070) (105 aa) fasta scores: E(): 0.17, 32.63% id in 95 aa NP_938834.1 Low similarity to Pseudomonas aeruginosa probable transcriptional regulator PA3689 TR:Q9HXV1 (EMBL:AE004788) (156 aa) fasta scores: E(): 2.1, 34.34% id in 99 aa NP_938837.1 Almost identical to already sequenced Corynebacterium diphtheriae histidine kinase CstS TR:Q9RPE8 (EMBL:AF161328) (408 aa) fasta scores: E(): 2e-149, 97.3% id in 408 aa NP_938838.1 Identical to previously sequenced Corynebacterium diphtheriae response regulator CstA TR:Q9RPE7 (EMBL:AF161328) (233 aa) fasta scores: E(): 4.9e-83, 99.57% id in 233 aa NP_938839.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding subunit 2SC6G5.39c TR:Q9K4B6 (EMBL:AL359152) (346 aa) fasta scores: E(): 9.6e-39, 44.02% id in 318 aa NP_938840.1 Low similarity to Streptomyces coelicolor integral membrane protein SCBAC17A6.12c TR:CAC44657 (EMBL:AL596248) (387 aa) fasta scores: E(): 0.021, 30.04% id in 213 aa NP_938842.1 Similar to Streptococcus pyogenes hypothetical protein SPY0576 TR:Q9A0X1 (EMBL:AE006514) (300 aa) fasta scores: E(): 2.3e-31, 36.93% id in 287 aa NP_938843.1 Low similarity to the central part of Alcaligenes eutrophus NrdG protein TR:Q9ZER3 (EMBL:AJ012479) (256 aa) fasta scores: E(): 6.4e-13, 37.5% id in 168 aa NP_938844.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates NP_938846.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_938847.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_938848.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_938849.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_938850.1 Similar to N-terminal region of Bacillus halodurans BH2297 protein TR:Q9KAJ0 (EMBL:AP001515) (232 aa) fasta scores: E(): 1.5e-08, 30.82% id in 146 aa NP_938851.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_938852.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_938853.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_938854.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_938855.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_938856.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_938857.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_938858.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_938859.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_938860.1 one of the stabilizing components for the large ribosomal subunit NP_938861.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_938862.1 C-terminal region presents los similarity to Streptococcus pneumoniae hypothetical protein SP0785 TR:AAK74922 (EMBL:AE007385) (399 aa) fasta scores: E(): 4e-08, 28.25% id in 315 aa NP_938863.1 Similar to Bacillus subtilis YknY protein TR:O31711 (EMBL:Z99111) (230 aa) fasta scores: E(): 3.2e-43, 57.01% id in 221 aa NP_938864.1 Similar to Bacillus halodurans BH3121 protein TR:Q9K885 (EMBL:AP001517) (398 aa) fasta scores: E(): 4e-20, 33.33% id in 438 aa NP_938865.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_938866.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_938867.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_938868.1 Similar to Escherichia coli serine transporter SdaC or DcrA or B2796 or Z4113 or ECS3656 SW:SDAC_ECOLI (P36559) (429 aa) fasta scores: E(): 4.6e-100, 61.66% id in 420 aa NP_938869.1 Similar to Escherichia coli L-serine dehydratase 1 SdaA or B1814 SW:SDHL_ECOLI (P16095) (454 aa) fasta scores: E(): 4.8e-113, 63.08% id in 447 aa NP_938870.1 Similar to Mycobacterium leprae probable L-asparaginase AnsA or ML1198 or MLCB458.13c SW:ASPG_MYCLE (Q9X7E6) (310 aa) fasta scores: E(): 6.4e-18, 36.39% id in 305 aa, and to Erwinia chrysanthemi L-asparaginase precursor AnsB or Asn SW:ASPG_ERWCH (P06608) (348 aa) fasta scores: E(): 2.5e-11, 30.9% id in 330 aa. Also similar to DIP1587, 306 aa; fasta scores: E(): 1.1e-48, 52.303% identity in 304 aa overlap. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRSFLG) at the N-terminal region NP_938871.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase NP_938872.1 N-terminal region similar to the C-terminal region of Synechococcus sp molybdenum cofactor biosynthesis protein CB MoaCB SW:MOCB_SYNP7 (Q56208) (319 aa) fasta scores: E(): 5.2e-09, 35.06% id in 154 aa and C-terminal region similar to Mycobacterium tuberculosis molybdopterin converting factor subunit 2 MoAE or Rv3119 or MT3201 or MTCY164.29 SWALL:MOAE_MYCTU (SWALL:O05795) (147 aa) fasta scores: E(): 5.7e-11, 38.97% id in 136 aa NP_938873.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 24.2 kDa protein MT2696 TR:AAK47012 (EMBL:AE007102) (224 aa) fasta scores: E(): 1.3e-10, 31.37% id in 204 aa NP_938874.1 N-terminal region similar to Mycobacterium tuberculosis molybdenum transport system permease ModB or Rv1858 or MT1906 or MTCY359.15c SW:MODB_MYCTU (P95156) blast scores: E(): 2e-32, score: 353 37% id, and C-terminal region to Mycobacterium tuberculosis molybdenum transport ATP-binding protein ModC or Rv1859 or MT1907 or MTCY359.14 SW:MODC_MYCTU (P95155) blast scores: E(): 1e-17, score: 93 28% id NP_938875.1 Similar to part of Escherichia coli molybdate-binding periplasmic protein precursor ModA or B0763 SW:MODA_ECOLI (P37329) (257 aa) fasta scores: E(): 0.36, 31.6% id in 193 aa NP_938876.1 Similar to Streptomyces coelicolor nitrate reductase gamma chain NarI TR:O86714 (EMBL:AL031515) (240 aa) fasta scores: E(): 1e-44, 49.78% id in 237 aa, and to Bacillus subtilis nitrate reductase gamma chain NarI SW:NARI_BACSU (P42177) (223 aa) fasta scores: E(): 6.2e-33, 42.27% id in 220 aa NP_938877.1 Similar to Streptomyces coelicolor nitrate reductase delta chain NarJ3 TR:Q9EWF5 (EMBL:AL451182) (220 aa) fasta scores: E(): 3e-20, 39.39% id in 198 aa, and to Bacillus subtilis nitrate reductase delta chain NarJ SW:NARJ_BACSU (P42178) (184 aa) fasta scores: E(): 1.9e-12, 29.14% id in 175 aa NP_938878.1 Similar to Bacillus subtilis nitrate reductase beta chain NarH SW:NARH_BACSU (P42176) (487 aa) fasta scores: E(): 1.4e-114, 56.31% id in 499 aa NP_938879.1 Similar to Escherichia coli respiratory nitrate reductase 1 alpha chain NarG or NarC or BisD or B1224 SW:NARG_ECOLI (P09152) (1246 aa) fasta scores: E(): 0, 46.16% id in 1237 aa NP_938880.1 Similar to Thermus thermophilus Nark2 TR:Q9RA45 (EMBL:AJ237974) (443 aa) fasta scores: E(): 2e-79, 50.22% id in 448 aa, and to Escherichia coli nitrite extrusion protein 2 NarU or B1469 SW:NARU_ECOLI (P37758) (462 aa) fasta scores: E(): 1.2e-31, 33.47% id in 472 aa NP_938881.1 Similar to Thermus thermophilus NarK1 TR:Q9RA46 (EMBL:AJ237974) (435 aa) fasta scores: E(): 2e-64, 59.56% id in 418 aa, and to Escherichia coli nitrite extrusion protein 1 NarK or B1223 SW:NARK_ECOLI (P10903) (463 aa) fasta scores: E(): 5.2e-17, 27.63% id in 427 aa NP_938882.1 Similar to Streptomyces coelicolor molybdenum cofactor biosynthesis protein MoaB TR:Q9RKA9 (EMBL:AL132674) (179 aa) fasta scores: E(): 7.6e-12, 35.13% id in 148 aa NP_938883.1 Similar to Rhodobacter capsulatus molybdopterin-guanine dinucleotide biosynthesis protein A MobA SW:MOBA_RHOCA (Q9X7K0) (190 aa) fasta scores: E(): 6.3e-05, 29.53% id in 193 aa, and to Pseudomonas putida molybdopterin-guanine dinucleotide biosynthesis protein A MobA SW:MOBA_PSEPU (Q9WWW0) (191 aa) fasta scores: E(): 0.00032, 28.71% id in 195 aa NP_938884.1 Similar to Streptomyces coelicolor molybdenum cofactor biosynthesis protein MoaC TR:Q9RKA8 (EMBL:AL132674) (170 aa) fasta scores: E(): 2.5e-29, 55.92% id in 152 aa, and to Escherichia coli, and molybdenum cofactor biosynthesis protein C MoaC or ChlA3 or B0783 or Z1002 or ECS0861 SW:MOAC_ECOLI (P30747) (160 aa) fasta scores: E(): 1.9e-19, 47.74% id in 155 aa NP_938885.1 Similar to Escherichia coli molybdopterin biosynthesis protein MoeA or ChlE or BisB or NarE or B0827 SW:MOEA_ECOLI (P12281) (411 aa) fasta scores: E(): 3.9e-25, 32.82% id in 326 aa NP_938886.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_938887.1 Similar to Agrobacterium tumefaciens Agr_C_1883p TR:AAK86832 (EMBL:AE008033) (294 aa) fasta scores: E(): 3.5e-20, 31.69% id in 306 aa, and to Bacillus subtilis dihydrodipicolinate synthase DapA SW:DAPA_BACSU (Q04796) (290 aa) fasta scores: E(): 1.1e-15, 29.68% id in 283 aa NP_938888.1 Similar to Bacillus subtilis oligopeptide transport ATP-binding protein OppF or Spo0KE SW:OPPF_BACSU (P24137) (308 aa) fasta scores: E(): 1.7e-36, 48.51% id in 235 aa NP_938889.1 C-terminal region similar to Salmonella typhimurium oligopeptide transport ATP-binding protein OppD or STM1743 SW:OPPD_SALTY (P04285) (335 aa) fasta scores: E(): 3.2e-38, 42.07% id in 328 aa, and N-terminal region to Bacillus firmus dipeptide transport system permease DppC SW:DPPC_BACFI (P94312) (304 aa) fasta scores: E(): 4.2e-32, 41.19% id in 267 aa NP_938890.1 Similar to Bacillus subtilis oligopeptide transport system permease AppB SW:APPB_BACSU (P42062) (317 aa) fasta scores: E(): 4.6e-31, 34.7% id in 317 aa NP_938891.1 Similar to Escherichia coli O157:H7 EDL933 transport protein Z1054 TR:AAG55204 (EMBL:AE005264) (512 aa) fasta scores: E(): 4.3e-19, 24% id in 479 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRDFFK) at the N-terminal region NP_938892.1 Doubtful CDS. No significant database matches NP_938893.1 Similar to Escherichia coli galactonate operon transcriptional repressor DgoR or B3694/B3695 SW:DGOR_ECOLI (P31460) (229 aa) fasta scores: E(): 8.4e-09, 23.11% id in 199 aa NP_938894.1 Similar to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 8e-13, 30.91% id in 317 aa NP_938895.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate NP_938896.1 Similar to Bacillus subtilis N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_BACSU (O34450) (396 aa) fasta scores: E(): 1.3e-23, 34.7% id in 389 aa, and to Escherichia coli, and N-acetylglucosamine-6-phosphate deacetylase NagA or B0677 or Z0824 or ECS0707 SW:NAGA_ECOLI (P15300) (382 aa) fasta scores: E(): 2.9e-18, 26.15% id in 390 aa NP_938897.1 Similar to Streptomyces coelicolor glucosamine phosphate isomerase SC7E4.33c TR:Q9K487 (EMBL:AL359214) (261 aa) fasta scores: E(): 5e-50, 54.44% id in 259 aa, and to Escherichia coli glucosamine-6-phosphate isomerase NagB or GlmD or B0678 or Z0825 or ECS0708 SW:NAGB_ECOLI (P09375) (266 aa) fasta scores: E(): 4.4e-32, 44.39% id in 223 aa NP_938898.1 Similar to Streptomyces coelicolor hypothetical 48.2 kDa protein SCC75A.17c TR:Q9RKQ7 (EMBL:AL133220) (477 aa) fasta scores: E(): 4.8e-06, 25.21% id in 353 aa NP_938900.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_938901.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_938902.1 binds 5S rRNA along with protein L5 and L25 NP_938903.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_938904.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_938905.1 late assembly protein NP_938906.1 Similar to Streptococcus pneumoniae transporter, FNT family, SP1215 TR:AAK75321 (EMBL:AE007421) (265 aa) fasta scores: E(): 1.4e-31, 42.24% id in 258 aa NP_938907.1 Similar to Mycobacterium tuberculosis FdhD protein homolog or Rv2899c or MT2967 or MTCY274.30c SW:FDHD_MYCTU (Q10820) (276 aa) fasta scores: E(): 0.0013, 28.34% id in 254 aa NP_938908.1 Similar to Streptomyces coelicolor alpha-glucosidase AglA TR:Q9KZ09 (EMBL:AL355752) (577 aa) fasta scores: E(): 2.2e-97, 48.09% id in 578 aa NP_938909.1 Similar to Bacillus coagulans oligo-1,6-glucosidase MalL SW:O16G_BACCO (Q45101) (555 aa) fasta scores: E(): 1.3e-26, 30.98% id in 539 aa NP_938910.1 Similar to Lactococcus lactis maltose ABC transporter substrate binding protein MalE TR:Q9CEZ8 (EMBL:AE006399) (410 aa) fasta scores: E(): 8.8e-35, 33.66% id in 407 aa NP_938911.1 Similar to Lactococcus lactis maltose ABC transporter permease MalF TR:Q9CEZ7 (EMBL:AE006399) (452 aa) fasta scores: E(): 9.4e-61, 39.15% id in 452 aa NP_938912.1 Similar to Streptococcus pneumoniae maltodextrin transport system permease MalD or SP2110 SW:MALD_STRPN (Q04699) (277 aa) fasta scores: E(): 2.9e-21, 30.85% id in 282 aa NP_938914.1 Similar to Streptomyces coelicolor hypothetical 46.2 kDa protein SC5F8.10c TR:Q9K4L4 (EMBL:AL357613) (410 aa) fasta scores: E(): 2.1e-74, 50% id in 394 aa NP_938915.1 Similar to Bacillus subtilis probable multiple sugar-binding transport ATP-binding protein MsmX SW:MSMX_BACSU (P94360) (365 aa) fasta scores: E(): 1.1e-54, 49.86% id in 367 aa NP_938916.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_938917.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_938918.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_938919.1 Similar to Micromonospora viridifaciens sialidase precursor NedA SW:NANH_MICVI (Q02834) (647 aa) fasta scores: E(): 4e-06, 33.62% id in 455 aa. Note: Contains a potential colied-coil region at residues 518..639 NP_938920.1 Similar to Streptomyces coelicolor secreted protein 3SC5B7.14c TR:Q9EWT5 (EMBL:AL449216) (231 aa) fasta scores: E(): 9.9e-08, 30.99% id in 242 aa NP_938921.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_938922.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_938923.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_938924.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_938925.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_938926.1 is a component of the macrolide binding site in the peptidyl transferase center NP_938927.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_938928.1 Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3556 TR:AAK47896 (EMBL:AE007159) (482 aa) fasta scores: E(): 8.1e-16, 29.36% id in 487 aa NP_938929.1 Low similarity to Streptomyces coelicolor membrane protein SCl2.30c TR:Q9L269 (EMBL:AL137778) (150 aa) fasta scores: E(): 1.9e-06, 35.48% id in 93 aa NP_938930.1 Similar to Streptomyces coelicolor serine protease SC3C3.08 TR:O86642 (EMBL:AL031231) (413 aa) fasta scores: E(): 4e-11, 32.37% id in 278 aa and to Mycobacterium tuberculosis hypothetical 46.0 kDa protein Rv3449 or MTCY13E12.02 or MT3555 SWALL:O06316 (EMBL:Z95390) (455 aa) fasta scores: E(): 4.7e-10, 38.11% id in 307 aa NP_938931.1 Very low similarity to Mycobacterium tuberculosis hypothetical protein Rv3448 or MTCY77.20 or MT3554 SWALL:O33354 (EMBL:Z95390) (467 aa) fasta scores: E(): 0.0016, 21.96% id in 478 aa. Note: Contains a sortase anchor site (LPNTG) NP_938932.1 Similar to Mycobacterium tuberculosis CDC1551 FtsK/SpoIIIE family protein MT3553 TR:AAK47893 (EMBL:AE007159) (1200 aa) fasta scores: E(): 1.7e-97, 37.59% id in 1221 aa NP_938934.1 Very low similarity to Mycobacterium tuberculosis hypothetical 13.5 kDa protein Rv3445c or MTCY77.17c TR:O06262 (EMBL:Z95389) (125 aa) fasta scores: E(): 0.0007, 31.52% id in 92 aa NP_938935.1 Similar to Mycobacterium tuberculosis hypothetical 11.1 kDa protein Rv3444c or MTCY77.16c TR:O06261 (EMBL:Z95389) (100 aa) fasta scores: E(): 1e-08, 35.48% id in 93 aa NP_938936.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_938937.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_938938.1 forms a direct contact with the tRNA during translation NP_938939.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_938941.1 No significant database matches. High concentration of alanine, glycine and proline residues NP_938943.1 Similar to Mycobacterium leprae hypothetical protein ML0370 TR:Q9CCV6 (EMBL:AL583918) (289 aa) fasta scores: E(): 6.4e-34, 42.46% id in 252 aa NP_938944.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer NP_938945.1 Similar to Mycobacterium tuberculosis hypothetical 18.2 kDa protein Rv3422c or MT3531 or MTCY78.07 SW:YY22_MYCTU (Q50706) (168 aa) fasta scores: E(): 4.4e-19, 46.71% id in 152 aa NP_938946.1 Similar to Escherichia coli O157:H7 transport protein ECS4625 TR:BAB38048 (EMBL:AP002566) (561 aa) fasta scores: E(): 3.1e-24, 29.47% id in 536 aa NP_938948.1 Similar to Mycobacterium leprae hypothetical 38.0 kDa protein ML0378 precursor or B229_C1_170 SW:YY21_MYCLE (Q49857) (359 aa) fasta scores: E(): 4.2e-30, 48.16% id in 218 aa NP_938949.1 Similar to Escherichia coli ribosomal-protein-alanine acetyltransferase RimI or B4373 or Z5974 or ECS5331 SW:RIMI_ECOLI (P09453) (148 aa) fasta scores: E(): 4.9e-09, 34.4% id in 125 aa NP_938950.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_938951.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_938952.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth NP_938953.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase NP_938955.1 Similar to Mycobacterium tuberculosis hypothetical 15.3 kDa protein Rv3412 or MT3521 or MTCY78.16C SW:YY12_MYCTU (Q50714) (136 aa) fasta scores: E(): 7.8e-18, 43.36% id in 113 aa NP_938956.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_938957.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_938958.1 Similar to Escherichia coli iron FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.6e-12, 28.57% id in 287 aa NP_938959.1 Similar to Escherichia coli iron FecC or B4289 SW:FECC_ECOLI (P15030) (332 aa) fasta scores: E(): 1.6e-22, 33.77% id in 305 aa NP_938960.1 Similar to Escherichia coli iron FecD or B4288 SW:FECD_ECOLI (P15029) (318 aa) fasta scores: E(): 2.6e-28, 35.01% id in 317 aa NP_938961.1 Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa NP_938962.1 Similar in its N-terminal region and C-terminal region to Rhizobium sp hypothetical 71.0 kDa protein Y4xN SW:Y4XN_RHISN (P55706) blast scores: E(): 3e-23, score: 277 22% id and also to Rhizobium meliloti rhizobactin siderophore biosynthesis protein RhbC or RhsC or RA1260 or SMA2404 SWALL:AAK65918 (EMBL:AF110737) (585 aa) fasta scores: E(): 6e-12, 26.23% id in 526 aa. Possible duplication NP_938963.1 Similar to Streptomyces coelicolor membrane transport protein SC5F8.19 TR:Q9K4K5 (EMBL:AL357613) (444 aa) fasta scores: E(): 7.2e-10, 27.72% id in 404 aa NP_938965.1 Similar to Streptomyces coelicolor integral membrane protein SCD10.06 TR:Q9K3X0 (EMBL:AL359988) (295 aa) fasta scores: E(): 6.6e-36, 43.82% id in 267 aa NP_938969.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_938973.1 Similar to Streptomyces coelicolor two-component system sensor kinase SCD63A.02 TR:Q9KY73 (EMBL:AL356832) (430 aa) fasta scores: E(): 3e-12, 37.09% id in 434 aa NP_938974.1 Similar to Streptomyces coelicolor two-component system DNA-binding response regulator SSCD63A.03 TR:Q9KY72 (EMBL:AL356832) (251 aa) fasta scores: E(): 3.8e-26, 58.72% id in 235 aa, and to Bacillus brevis transcriptional regulatory protein DegU SW:DEGU_BACBR (P54662) (236 aa) fasta scores: E(): 2.7e-10, 30.97% id in 226 aa NP_938978.1 Similar to Mycobacterium tuberculosis hypothetical 56.7 kDa protein Rv3394c or MTV004.52c TR:O50419 (EMBL:AL009198) (527 aa) fasta scores: E(): 2e-34, 32.63% id in 527 aa NP_938980.1 Similar to Corynebacterium glutamicum hypothetical 31.3 kDa protein TR:Q93QX1 (EMBL:AF159510) (287 aa) fasta scores: E(): 3.9e-56, 51.52% id in 295 aa NP_938981.1 Similar to Mycobacterium tuberculosis hypothetical 33.4 kDa protein Rv3104c or MTCY164.14c TR:O05781 (EMBL:Z95150) (308 aa) fasta scores: E(): 1.3e-15, 33.94% id in 271 aa NP_938982.1 Similar to Staphylococcus aureus (strain N315) SA0421 protein or SAV0463 TR:BAB56625 (EMBL:AP003130) (219 aa) fasta scores: E(): 1.7e-31, 46.6% id in 206 aa, and to Salmonella enteritidis integral membrane protein SfbC TR:Q9S4Y9 (EMBL:AF102556) (202 aa) fasta scores: E(): 8.9e-28, 42.71% id in 199 aa NP_938983.1 Similar to Bacillus halodurans ABC transporter BH3481 TR:Q9K789 (EMBL:AP001518) (338 aa) fasta scores: E(): 1.1e-47, 48.61% id in 325 aa, and to N-terminal region of Escherichia coli ATP-binding protein ABC or B0199 SW:ABC_ECOLI (P30750) (343 aa) fasta scores: E(): 3.9e-43, 55.2% id in 250 aa NP_938984.1 Similar to Escherichia coli lipoprotein-28 precursor NlpA or B3661 SW:NLPA_ECOLI (P04846) (272 aa) fasta scores: E(): 1.9e-20, 34.36% id in 259 aa. Possible duplication of the CDS upstream, CDIP0611 (66.667% identity in 288 aa overlap) NP_938985.1 Similar to Escherichia coli lipoprotein-28 precursor NlpA or B3661 SW:NLPA_ECOLI (P04846) (272 aa) fasta scores: E(): 1.5e-20, 33.83% id in 266 aa. Possible duplication of the CDS downstream, CDIP0610 (66.667% identity in 288 aa overlap) NP_938986.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. NP_938987.1 Similar to Streptomyces coelicolor integral membrane protein SCE126.11 TR:Q9X854 (EMBL:AL049630) (151 aa) fasta scores: E(): 1.4e-15, 41.21% id in 148 aa NP_938988.1 Similar to Streptomyces coelicolor hypothetical 47.7 kDa protein SCE9.01 TR:Q9X8H4 (EMBL:AL049841) (436 aa) fasta scores: E(): 8.3e-18, 28.97% id in 428 aa NP_938989.1 Similar to Yersinia pestis periplasmic chelated iron-binding protein YfeA precursor or YPO2439 SW:YFEA_YERPE (Q56952) (311 aa) fasta scores: E(): 1.8e-19, 30.03% id in 303 aa NP_938990.1 Similar to Yersinia pestis chelated iron transport system membrane protein YfeB or YPO2440 SW:YFEB_YERPE (Q56953) (296 aa) fasta scores: E(): 1.7e-20, 37.05% id in 251 aa NP_938991.1 Similar to Yersinia pestis chelated iron transport system membrane protein YfeC or YPO2441 SW:YFEC_YERPE (Q56954) (294 aa) fasta scores: E(): 1.6e-13, 26.81% id in 276 aa NP_938992.1 Similar to Lactococcus lactis manganese ABC transporter permease MtsC TR:Q9CFZ4 (EMBL:AE006363) (281 aa) fasta scores: E(): 3.3e-13, 27.96% id in 261 aa NP_938993.1 Similar to Mycobacterium tuberculosis iron-dependent repressor IdeR or DtxR or Rv2711 or MT2784 or MTCY05A6.32 SW:IDER_MYCTU (Q50495) (230 aa) fasta scores: E(): 1.1e-10, 31.84% id in 201 aa and low similarity to Corynebacterium diphtheriae diphtheria toxin repressor DtxR SW:DTXR_CORDI (P33120) (226 aa) fasta scores: E(): 7.7e-08, 35.08% identity in 114 aa overlap NP_938994.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_938997.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine NP_938999.1 Similar to the C-terminal region of Corynebacterium ulcerans HtaA TR:Q9EZ58 (EMBL:AF304009) (410 aa) fasta scores: E(): 4.9e-58, 54.14% id in 410 aa, and to Streptomyces coelicolor hypothetical 48.2 kDa protein SCC75A.17c TR:Q9RKQ7 (EMBL:AL133220) (477 aa) fasta scores: E(): 4.9e-06, 26.25% id in 579 aa NP_939000.1 Identical to previously sequenced Corynebacterium diphtheriae HmuT precursor TR:Q9XD89 (EMBL:AF109162) (353 aa) fasta scores: E(): 3.9e-123, 98.86% id in 353 aa, and highly similar to Corynebacterium ulcerans hemin receptor precursor HmuT TR:Q9EZ57 (EMBL:AF304009) (351 aa) fasta scores: E(): 2.6e-99, 79.83% id in 352 aa NP_939001.1 Almost identical to previously sequenced Corynebacterium diphtheriae HmuU TR:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 6.1e-120, 98% id in 350 aa, and highly similar to Corynebacterium ulcerans permease HmuU TR:Q9EZ56 (EMBL:AF304009) (350 aa) fasta scores: E(): 4.3e-100, 81.14% id in 350 aa NP_939002.1 Almost identical to the previously sequenced Corynebacterium diphtheriae HmuV TR:Q9XD87 (EMBL:AF109162) (277 aa) fasta scores: E(): 3.2e-88, 97.83% id in 277 aa, and to Escherichia coli iron (III) dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 1.2e-23, 41.94% id in 236 aa NP_939003.1 Almost identical to previously sequenced Corynebacterium diphtheriae secreted protein precursor TR:Q9XD85 (EMBL:AF109162) (339 aa) fasta scores: E(): 2.9e-99, 89.21% id in 306 aa NP_939004.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol NP_939005.1 Highly similar to Corynebacterium glutamicum isocitrate dehydrogenase [NADP] Icd SW:IDH_CORGL (P50216) (738 aa) fasta scores: E(): 0, 83.31% id in 737 aa NP_939006.1 Similar to Rhizobium meliloti transport transmembrane protein SMC02161 TR:CAC41922 (EMBL:AL591783) (411 aa) fasta scores: E(): 5.7e-56, 46.61% id in 384 aa, and to Streptomyces coelicolor transmembrane efflux protein SC1G2.16c TR:Q9RDR3 (EMBL:AL136500) (413 aa) fasta scores: E(): 4.7e-46, 41.62% id in 370 aa NP_939007.1 Similar to Streptomyces coelicolor exodeoxyribonuclease SCE87.25c TR:Q9RKB3 (EMBL:AL132674) (274 aa) fasta scores: E(): 2.6e-27, 44.3% id in 307 aa NP_939009.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_939010.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3439 TR:AAK47783 (EMBL:AE007151) (289 aa) fasta scores: E(): 1.6e-33, 33.91% id in 286 aa NP_939011.1 Similar to Mycobacterium leprae D-alanyl-D-alanine carboxypeptidase ML0691 TR:Q9CCM2 (EMBL:AL583919) (411 aa) fasta scores: E(): 6.2e-45, 40.1% id in 389 aa, and to Bacillus subtilis penicillin-binding protein 5* precursor DacB SW:DACB_BACSU (P35150) (382 aa) fasta scores: E(): 2e-13, 30.26% id in 261 aa NP_939012.1 Low similarity to C-terminal region of Streptomyces coelicolor adenosine deaminase SC5H1.24c TR:Q9X7T2 (EMBL:AL049863) (359 aa) fasta scores: E(): 2.1e-06, 28.88% id in 225 aa NP_939013.1 Similar to Mycobacterium tuberculosis hypothetical 45.7 kDa protein Rv3311 or MTV016.10 TR:O53362 (EMBL:AL021841) (420 aa) fasta scores: E(): 1.4e-25, 34.05% id in 417 aa NP_939014.1 C-terminal region similar to C-terminal region of Mycobacterium leprae secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 4.6e-12, 37.57% id in 173 aa NP_939016.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_939018.1 Similar to Mycobacterium tuberculosis CDC1551 hydrolase, Ama/HipO/HyuC family MT3404 TR:AAK47747 (EMBL:AE007149) (389 aa) fasta scores: E(): 4.5e-74, 49.74% id in 388 aa NP_939019.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity NP_939020.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate NP_939021.1 Similar to Streptococcus pyogenes hypothetical protein SPY1216 TR:Q99ZI6 (EMBL:AE006562) (270 aa) fasta scores: E(): 3.2e-07, 33.82% id in 136 aa NP_939023.1 Similar to Corynebacterium glutamicum acyl coenzyme A carboxylase AccBC TR:P71122 (EMBL:U35023) (591 aa) fasta scores: E(): 1.5e-188, 85.47% id in 592 aa, and to Mycobacterium leprae acetyl-/propionyl-coenzyme A carboxylase alpha chain [includes: biotin carboxylase ; biotin carboxyl carrier protein(BCCP)] BccA or ML0726 or B1308_C1_129 SW:BCCA_MYCLE (P46392) (598 aa) fasta scores: E(): 1.1e-159, 72.46% id in 592 aa NP_939024.1 Similar to Mycobacterium tuberculosis thiosulfate sulfurtransferase SseA or Rv3283 or MT3382 or MTCY71.23 SW:THT2_MYCTU (P96888) (297 aa) fasta scores: E(): 1.5e-78, 60.67% id in 295 aa, and to Corynebacterium glutamicum thiosulfate sulfurtransferase ThtR SW:THTR_CORGL (P71121) (225 aa) fasta scores: E(): 1.2e-56, 63.72% id in 215 aa NP_939025.1 Similar to Campylobacter jejuni hypothetical protein CJ0069 TR:Q9PJ50 (EMBL:AL139074) (343 aa) fasta scores: E(): 3e-85, 61.36% id in 352 aa NP_939026.1 Similar to Mycobacterium leprae conserved membrane protein ML1213 TR:Q9CC68 (EMBL:AL583921) (733 aa) fasta scores: E(): 1.2e-78, 38.27% id in 708 aa NP_939027.1 Similar to Mycobacterium leprae hypothetical 14.5 kDa protein ML0284 or MLCB4.27c TR:O69598 (EMBL:AL023514) (137 aa) fasta scores: E(): 3.5e-22, 50% id in 140 aa NP_939028.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell NP_939029.1 Similar to Streptomyces coelicolor carbohydrate kinase SCC57A.19 TR:Q9RDH9 (EMBL:AL136519) (306 aa) fasta scores: E(): 1.3e-32, 44.06% id in 295 aa, and to Escherichia coli ribokinase RbsK or B3752 or Z5253 or ECS4694 SW:RBSK_ECOLI (P05054) (309 aa) fasta scores: E(): 4.3e-24, 35.69% id in 297 aa NP_939030.1 Similar to Streptomyces coelicolor probable lacI-family transcriptional regulator SCC57A.16 TR:Q9RDI2 (EMBL:AL136519) (347 aa) fasta scores: E(): 5.5e-32, 34.04% id in 326 aa, and to Bacillus megaterium glucose-resistance amylase regulator CcpA SW:CCPA_BACME (P46828) (332 aa) fasta scores: E(): 5.1e-24, 29.17% id in 329 aa NP_939032.1 Similar to Corynebacterium glutamicum DtsR2 protein TR:O87201 (EMBL:AB018531) (537 aa) fasta scores: E(): 2e-182, 87.87% id in 536 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 5.2e-137, 64.83% id in 546 aa. Possible duplication of DIP0660 (69.309% identity in 492 aa overlap) NP_939034.1 Similar to Corynebacterium glutamicum DtsR1 protein TR:O88155 (EMBL:AB018531) (543 aa) fasta scores: E(): 1.5e-173, 81.76% id in 543 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 2.7e-127, 59.89% id in 546 aa. Possible duplication of DIP0658 (69.309% identity in 492 aa overlap) NP_939035.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon NP_939037.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_939038.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway NP_939039.1 Similar to the C-terminal region of Lactococcus lactis hypothetical protein YebE TR:Q9CIF2 (EMBL:AE006277) (194 aa) fasta scores: E(): 2.7e-05, 36.76% id in 136 aa NP_939040.1 Similar to Escherichia coli hydrogenase isoenzymes formation protein HypD or B2729 SW:HYPD_ECOLI (P24192) (373 aa) fasta scores: E(): 4.1e-77, 51.73% id in 375 aa, and to Nostoc punctiforme HypD-like protein TR:Q9EYH5 (EMBL:AF325724) (392 aa) fasta scores: E(): 8.7e-94, 58.74% id in 366 aa NP_939041.1 Similar to Rhodobacter capsulatus hydrogenase expression/formation protein HypC SW:HYPC_RHOCA (P40428) (96 aa) fasta scores: E(): 4.7e-09, 50% id in 82 aa, and to Escherichia coli hydrogenase-2 operon protein HybG or B2990 or Z4344 or ECS3875 SW:HYBG_ECOLI (P37185) (82 aa) fasta scores: E(): 8e-08, 44% id in 75 aa NP_939042.1 Similar to Rhodobacter capsulatus hydrogenase expression/formation protein HypE SW:HYPE_RHOCA (P26412) (340 aa) fasta scores: E(): 8e-46, 49.7% id in 336 aa, and to Escherichia coli hydrogenase isoenzymes formation protein HypE or B2730 SW:HYPE_ECOLI (P24193) (322 aa) fasta scores: E(): 5.7e-38, 43.03% id in 323 aa NP_939043.1 Similar to Azotobacter chroococcum MCD 1 hydrogenase maturation protein HypF or HupY SW:HYPF_AZOCH (Q43950) (776 aa) fasta scores: E(): 2.5e-73, 37.62% id in 784 aa, and to Escherichia coli hydrogenase maturation protein HypF or HydA or B2712 SW:HYPF_ECOLI (P30131) (750 aa) fasta scores: E(): 1e-43, 38.82% id in 765 aa NP_939044.1 Similar to Nostoc punctiforme hydrogenase nickel incorporation protein HypA SW:HYPA_NOSPU (Q9EYH3) (113 aa) fasta scores: E(): 4.6e-06, 30.35% id in 112 aa, and to Rhodobacter capsulatus hydrogenase nickel incorporation protein HypA or HupL SW:HYPA_RHOCA (P26409) (113 aa) fasta scores: E(): 0.0006, 27.67% id in 112 aa NP_939045.1 Similar to Rhodobacter capsulatus hydrogenase nickel incorporation protein HypB or HupM SW:HYPB_RHOCA (P26410) (335 aa) fasta scores: E(): 1.3e-34, 45.78% id in 249 aa, and to Escherichia coli hydrogenase isoenzymes nickel incorporation protein HypB or B2727 SW:HYPB_ECOLI (P24190) (290 aa) fasta scores: E(): 7.4e-34, 44.58% id in 231 aa NP_939046.1 Similar to Azotobacter vinelandii uptake hydrogenase small subunit precursor HoxK SW:MBHS_AZOVI (P21950) (358 aa) fasta scores: E(): 4.6e-64, 45.75% id in 365 aa, and to Escherichia coli hydrogenase-1 small chain precursor HyaA or B0972 SW:MBHS_ECOLI (P19928) (372 aa) fasta scores: E(): 1.3e-58, 42.54% id in 369 aa NP_939047.1 Similar to Bradyrhizobium japonicum uptake hydrogenase large subunit HupB or HupL SW:MBHL_BRAJA (P12636) (596 aa) fasta scores: E(): 2.8e-98, 45% id in 591 aa, and to Escherichia coli hydrogenase-1 large chain HyaB or B0973 SW:MBHL_ECOLI (P19927) (597 aa) fasta scores: E(): 2.5e-91, 41.25% id in 589 aa NP_939048.1 Similar to Bradyrhizobium japonicum probable Ni/Fe-hydrogenase B-type cytochrome subunit HupC SW:CYBH_BRAJA (P21960) (244 aa) fasta scores: E(): 2.3e-16, 32.65% id in 245 aa, and to Escherichia coli probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit HyaC or B0974 or Z1391 or ECS1130 SW:CYBH_ECOLI (P19929) (235 aa) fasta scores: E(): 6e-13, 30.04% id in 213 aa and N-terminal region similar to Homo sapiens vacuolar proton translocating ATPase 116 kDa subunit A isoform 2 SW:VPP2_HUMAN (Q9Y487) blast scores: E(): 2.6, score: 34 30% id NP_939049.1 Similar to Escherichia coli hydrogenase 2 maturation protease HybD or B2993 SW:HYBD_ECOLI (P37182) (164 aa) fasta scores: E(): 6.6e-12, 34.88% id in 172 aa NP_939050.1 Similar to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HypA SW:HYPA_BRAJA (Q45256) (113 aa) fasta scores: E(): 4e-06, 28.07% id in 114 aa NP_939051.1 Similar to Methanococcus voltae methylviologen-reducing hydrogenase Vhu alpha subunit VhuA TR:Q00407 (EMBL:X61204) (420 aa) fasta scores: E(): 9e-06, 24.37% id in 398 aa NP_939052.1 Similar to Azotobacter vinelandii probable hydrogenase expression/formation protein HypC or HupF SW:HYPC_AZOVI (P31881) (84 aa) fasta scores: E(): 8.5e-06, 36.25% id in 80 aa, and to Escherichia coli hydrogenase-2 operon protein HybG or B2990 or Z4344 or ECS3875 SW:HYBG_ECOLI (P37185) (82 aa) fasta scores: E(): 0.0017, 28.94% id in 76 aa NP_939053.1 Similar to Mycobacterium tuberculosis hypothetical 23.7 kDa protein Rv3268 or MTCY71.08 TR:P96873 (EMBL:Z92771) (229 aa) fasta scores: E(): 7.6e-11, 31.48% id in 235 aa NP_939054.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3367 TR:AAK47708 (EMBL:AE007146) (497 aa) fasta scores: E(): 6e-73, 50.1% id in 469 aa NP_939055.1 Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT3365 TR:AAK47706 (EMBL:AE007146) (301 aa) fasta scores: E(): 5.1e-56, 52.12% id in 282 aa NP_939056.1 Similar to Mycobacterium tuberculosis CDC1551 mannose-1-phosphate guanyltransferase MT3364 TR:AAK47705 (EMBL:AE007146) (359 aa) fasta scores: E(): 1e-93, 70.45% id in 352 aa NP_939057.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939058.1 Highly similar on its C-terminal region to the C-terminal region of Streptomyces coelicolor regulatory protein WhiB TR:Q53963 (EMBL:X62287) (87 aa) fasta scores: E(): 2.4e-22, 82.6% id in 69 aa NP_939059.1 Similar to Mycobacterium tuberculosis hypothetical 15.6 kDa protein Rv3259 or MTV015.04 TR:O53352 (EMBL:AL021840) (139 aa) fasta scores: E(): 4.2e-21, 50% id in 136 aa NP_939060.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 16.8 kDa protein MT3356 TR:AAK47698 (EMBL:AE007146) (163 aa) fasta scores: E(): 8.5e-16, 47.65% id in 149 aa NP_939061.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells NP_939062.1 Similar in its N-terminal region to Mycobacterium tuberculosis hypothetical 35.3 kDa protein Rv3256c or MTV015.01c or MTCY20b11.31c TR:O05899 (EMBL:Z95121) (346 aa) fasta scores: E(): 5.1e-06, 27.69% id in 260 aa NP_939063.1 Similar to Mycobacterium tuberculosis CDC1551 mannose-6-phosphate isomerase MT3353 TR:AAK47695 (EMBL:AE007145) (408 aa) fasta scores: E(): 1.6e-57, 47.43% id in 409 aa, and to Escherichia coli mannose-6-phosphate isomerase ManA or Pmi or B1613 SW:MANA_ECOLI (P00946) (391 aa) fasta scores: E(): 1.7e-24, 38.34% id in 399 aa NP_939064.1 No significant database matches. Contains various regions with high content in proline amino acid residues NP_939066.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine NP_939067.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_939068.1 Similar to Mycobacterium tuberculosis MtrA protein or Rv3246c or MTCY20B11.21c TR:Q50447 (EMBL:Z95121) (228 aa) fasta scores: E(): 7.6e-61, 70.66% id in 225 aa, and to Streptomyces coelicolor transcriptional regulatory protein AfsQ1 or 2SCK8.33c SW:AFQ1_STRCO (Q04942) (225 aa) fasta scores: E(): 2.4e-36, 45.2% id in 219 aa NP_939069.1 Similar to Mycobacterium tuberculosis MtrB or Rv3245c or MTCY20B11.20c TR:O05890 (EMBL:Z95121) (567 aa) fasta scores: E(): 4.6e-89, 53.73% id in 482 aa, and to Streptomyces coelicolor sensor protein AfsQ2 or 2SCK8.32c SW:AFQ2_STRCO (Q04943) (535 aa) fasta scores: E(): 1.4e-23, 30.64% id in 447 aa NP_939070.1 Similar to Mycobacterium tuberculosis hypothetical 61.2 kDa protein LpqB or Rv3244c or MTCY20B11.19c TR:O05889 (EMBL:Z95121) (583 aa) fasta scores: E(): 1.6e-14, 28.76% id in 591 aa NP_939071.1 Similar to Mycobacterium tuberculosis hypothetical 22.5 kDa protein Rv3242c or MTCY20B11.17c TR:O05887 (EMBL:Z95121) (213 aa) fasta scores: E(): 8.3e-21, 41.5% id in 212 aa NP_939072.1 Similar to Mycobacterium leprae hypothetical protein ML0778 TR:Q9CCI7 (EMBL:AL583919) (229 aa) fasta scores: E(): 4.6e-35, 48.41% id in 221 aa NP_939073.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_939075.1 Similar to C-terminal region of Mycobacterium tuberculosis CDC1551 hydrolase, haloacid dehalogenase-like family MT3486 TR:AAK47822 (EMBL:AE007155) (217 aa) fasta scores: E(): 0.0053, 32.35% id in 136 aa NP_939076.1 Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv3231c or MTCY20B11.06c TR:O05876 (EMBL:Z95121) (169 aa) fasta scores: E(): 2.4e-25, 53.52% id in 170 aa NP_939077.1 Similar to Mycobacterium tuberculosis hypothetical 40.8 kDa protein Rv3230c or MTCY20B11.05c TR:O05875 (EMBL:Z95121) (380 aa) fasta scores: E(): 4.8e-60, 49.14% id in 350 aa, and to Escherichia coli NADH oxidoreductase Hcr or B0872 SW:HCR_ECOLI (P75824) (322 aa) fasta scores: E(): 1.9e-13, 28.71% id in 296 aa NP_939078.1 Similar to Mycobacterium tuberculosis hypothetical 48.4 kDa protein DesA3 or Rv3229c or MTCY20B11.04c TR:O05874 (EMBL:Z95121) (427 aa) fasta scores: E(): 1.5e-86, 52.59% id in 405 aa NP_939079.1 Similar to Mycobacterium tuberculosis hypothetical 34.9 kDa protein Rv3228 or MTCY20B11.03 TR:O05873 (EMBL:Z95121) (330 aa) fasta scores: E(): 9.1e-70, 60.18% id in 324 aa NP_939080.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_939081.1 Similar to Halobacterium sp VNG0686c TR:Q9HRI0 (EMBL:AE005014) (229 aa) fasta scores: E(): 4.5e-12, 35.51% id in 245 aa NP_939082.1 Similar to Escherichia coli protein YbaK or B0481 SW:YBAK_ECOLI (P37175) (159 aa) fasta scores: E(): 1.2e-21, 46.49% id in 157 aa NP_939083.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response NP_939084.1 Similar to Streptomyces coelicolor anti-sigma factor RsrA TR:Q9RL96 (EMBL:AJ010320) (105 aa) fasta scores: E(): 5.5e-06, 35.71% id in 70 aa NP_939086.1 Similar to Mycobacterium leprae transcriptional regulator WhiB1 or ML0804 TR:Q9CCH7 (EMBL:AL583919) (84 aa) fasta scores: E(): 1.5e-29, 81.7% id in 82 aa NP_939088.1 Similar to Mycobacterium leprae membrane protein ML0806 TR:Q9CCH6 (EMBL:AL583919) (173 aa) fasta scores: E(): 2e-07, 38.34% id in 133 aa NP_939089.1 Low similarity to Mycobacterium leprae membrane protein ML0810 TR:Q9CCH4 (EMBL:AL583919) (407 aa) fasta scores: E(): 1.1e-21, 26.81% id in 414 aa NP_939090.1 Similar to Mycobacterium leprae ATP-dependent RNA helicase RhlE or ML0811 TR:Q9CCH3 (EMBL:AL583919) (544 aa) fasta scores: E(): 2.1e-87, 55.78% id in 441 aa, and to Klebsiella pneumoniae cold-shock dead-box protein A DeaD or CsdA SW:DEAD_KLEPN (P33906) (642 aa) fasta scores: E(): 5.7e-49, 41.91% id in 377 aa NP_939091.1 Doubtful CDS. No significant database matches NP_939092.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 10.1 kDa protein MT3304 TR:AAK47646 (EMBL:AE007142) (97 aa) fasta scores: E(): 4.5e-11, 51.38% id in 72 aa NP_939093.1 Similar to Mycobacterium tuberculosis hypothetical 31.0 kDa protein Rv3207c or MTCY07D11.19 TR:O05859 (EMBL:Z95120) (285 aa) fasta scores: E(): 1.7e-44, 46.69% id in 287 aa NP_939094.1 Similar to Mycobacterium leprae hypothetical protein ML0818 TR:Q9CCG7 (EMBL:AL583919) (297 aa) fasta scores: E(): 1.2e-34, 39.47% id in 266 aa NP_939095.1 Similar to Streptomyces coelicolor ATP-dependent DNA helicase 2SC3B6.07 TR:Q9FCK5 (EMBL:AL390968) (1159 aa) fasta scores: E(): 6.2e-29, 32.21% id in 1161 aa NP_939096.1 Similar to Mycobacterium tuberculosis CDC1551 helicase, UvrD/Rep family MT3295 TR:AAK47638 (EMBL:AE007142) (1101 aa) fasta scores: E(): 2.9e-25, 43.03% id in 1120 aa NP_939097.1 Similar to Mycobacterium tuberculosis CDC1551 transporter, MT3294 TR:AAK47637 (EMBL:AE007142) (355 aa) fasta scores: E(): 2.5e-75, 61.78% id in 348 aa, and to Escherichia coli potassium channel protein Kch or B1250 SW:KCH_ECOLI (P31069) (417 aa) fasta scores: E(): 1.5e-07, 26.06% id in 234 aa NP_939098.1 Similar to C-terminal region of Vibrio cholerae NADH pyrophosphatase NudC or VC0331 SW:NUDC_VIBCH (Q9KV27) (269 aa) fasta scores: E(): 2.3e-11, 32.75% id in 174 aa NP_939099.1 Similar to Mycobacterium tuberculosis probable DNA helicase II homolog UvrD or Rv3198c or MT3291 or MTV014.42c SW:UVRD_MYCTU (O53344) (700 aa) fasta scores: E(): 2.7e-133, 58.92% id in 689 aa, and to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or RecL or B3813 SW:UVRD_ECOLI (P03018) (720 aa) fasta scores: E(): 7.8e-37, 32.16% id in 656 aa NP_939100.1 Low similarity to Mycobacterium tuberculosis CDC1551 hypothetical 31.6 kDa protein MT3288 TR:AAK47629 (EMBL:AE007141) (299 aa) fasta scores: E(): 3.9e-06, 28.12% id in 288 aa NP_939101.1 Similar to Streptomyces coelicolor hypothetical 19.2 kDa protein 2SC3B6.18 TR:Q9FCJ4 (EMBL:AL390968) (168 aa) fasta scores: E(): 2e-25, 46% id in 150 aa NP_939102.1 Similar to Mycobacterium tuberculosis hypothetical 49.4 kDa protein Rv3195 or MTV014.39 TR:O53341 (EMBL:AL021646) (472 aa) fasta scores: E(): 5.1e-65, 45.37% id in 432 aa NP_939103.1 Similar to Mycobacterium leprae secreted protein ML0643 TR:Q9CCM7 (EMBL:AL583919) (340 aa) fasta scores: E(): 5.2e-46, 43.42% id in 350 aa NP_939106.1 Similar to Mycobacterium tuberculosis integral membrane protein Rv3193c or MTV014.37c TR:O53339 (EMBL:AL021646) (992 aa) fasta scores: E(): 1e-154, 46.03% id in 1008 aa NP_939109.1 C-terminal region similar to Drosophila erecta trypsin zeta precursor Try-ZetA SW:TRYZ_DROER (P54630) (281 aa) fasta scores: E(): 0.17, 26.03% id in 242 aa NP_939111.1 Doubtful CDS. No significant database matches NP_939112.1 Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source NP_939113.1 Similar to Propionigenium modestum methylmalonyl-CoA decarboxylase, alpha-subunit MmdA TR:O54028 (EMBL:AJ002015) (512 aa) fasta scores: E(): 2.2e-105, 54.1% id in 512 aa, and to Bacillus subtilis propionyl-CoA carboxylase beta chain YqjD SW:PCCB_BACSU (P54541) (506 aa) fasta scores: E(): 9.2e-91, 50.1% id in 497 aa NP_939115.1 Similar to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl- transferase SW:BCCP_PROFR (P02904) (123 aa) fasta scores: E(): 2.6e-15, 49.18% id in 122 aa NP_939117.1 Similar to Mycobacterium tuberculosis hypothetical 27.7 kDa protein Rv3137 or MTCY03A2.21c TR:P95189 (EMBL:Z83867) (260 aa) fasta scores: E(): 1.4e-65, 63.42% id in 257 aa NP_939118.1 Similar to Rhizobium loti myo-inositol-1-monophosphotase MLR4874 TR:Q98D39 (EMBL:AP003005) (264 aa) fasta scores: E(): 1.9e-18, 32.92% id in 243 aa, and to Streptomyces spectabilis myo-inositol-1-monophosphotase SpcA TR:Q9L630 (EMBL:AF244574) (265 aa) fasta scores: E(): 3.8e-14, 31.59% id in 269 aa NP_939119.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_939120.1 Similar to Neisseria gonorrhoeae efflux pump component MtrF TR:Q9RNX1 (EMBL:AF176821) (522 aa) fasta scores: E(): 2.4e-35, 40.03% id in 527 aa, and to Escherichia coli aminobenzoyl-glutamate transport protein AbgT or B1336 SW:ABGT_ECOLI (P46133) (510 aa) fasta scores: E(): 1.7e-28, 34.72% id in 527 aa NP_939121.1 Similar to Streptomyces coelicolor cell division ATP-binding protein FtsE TR:Q9L1S6 (EMBL:AL138851) (229 aa) fasta scores: E(): 2.6e-43, 61.06% id in 226 aa, and to Escherichia coli cell division ATP-binding protein FtsE or B3463 or Z4837 or ECS4312 SW:FTSE_ECOLI (P10115) (222 aa) fasta scores: E(): 5.9e-26, 43.36% id in 226 aa NP_939122.1 Similar to Mycobacterium leprae cell division protein FtsX homolog or ML0670 or MLCB1779.20c SW:FTSX_MYCLE (O32882) (297 aa) fasta scores: E(): 3.4e-41, 41.19% id in 301 aa, and to Escherichia coli cell division protein FtsX or FtsS or B3462 SW:FTSX_ECOLI (P10122) (352 aa) fasta scores: E(): 3.5e-06, 25% id in 240 aa NP_939123.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_939124.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939125.1 Similar to Escherichia coli possible transposase of IS1353 YahA TR:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 2.6e-62, 41.595% id in 464 aa, and to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 2.7e-35, 38.628% id in 277 aa NP_939126.1 Similar to Staphylococcus aureus lantibiotic modifying enzyme TR:Q9S4D1 (EMBL:AF147744) (965 aa) fasta scores: E(): 5.3e-32, 21.471% id in 1006 aa, and to Lactococcus lactis Plasmid pMRC01 lacticin 481/lactococcin biosynthesis protein LcnDR2 TR:O87238 (EMBL:AE001272) (980 aa) fasta scores: E(): 2.6e-16, 21.221% id in 999 aa NP_939127.1 Similar to Staphylococcus aureus transporter TR:Q9S4D0 (EMBL:AF147744) (720 aa) fasta scores: E(): 2.4e-57, 29.986% id in 707 aa, and to Lactococcus lactis cytolysin B transport protein TR:O87239 (EMBL:AE001272) (708 aa) fasta scores: E(): 7.1e-55, 28.571% id in 714 aa NP_939128.1 Similar to Bacillus subtilis SpaF TR:Q45404 (EMBL:U09819) (247 aa) fasta scores: E(): 2.2e-22, 42.991% id in 214 aa, and to Corynebacterium jeikeium BlsD TR:AAK94047 (EMBL:AF401314) (301 aa) fasta scores: E(): 2.5e-22, 33.106% id in 293 aa NP_939129.1 Similar to Streptomyces coelicolor ABC transporter integral membrane protein SCE8.16c TR:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 0.0032, 26.695% id in 236 aa, and to Corynebacterium jeikeium BlsC TR:AAK94048 (EMBL:AF401314) (247 aa) fasta scores: E(): 0.81, 21.116% id in 251 aa NP_939130.1 Similar to part of Yersinia enterocolitica IS1222-like transposase TR:Q9X9I1 (EMBL:AJ132945) (165 aa) fasta scores: E(): 5.3e-08, 40.625% id in 64 aa, and of Xanthomonas campestris insertion element IS476 hypothetical 39.2 kDa protein SW:YI61_XANCA (P25438) (346 aa) fasta scores: E(): 3.3e-06, 34.722% id in 72 aa. Also similar to the C-terminal region of DIP0760, transposase (pseudogene) (361 aa) fasta scores: E(): 9.6e-27, 80.000% identity in 70 aa overlap NP_939131.1 Similar to part of Salmonella typhimurium LT2 integrase core domain STM2764 TR:AAL21650 (EMBL:AE008826) (155 aa) fasta scores: E(): 0.94, 36.36% id in 44 aa NP_939132.1 Similar to part of Mycobacterium ulcerans probable transposase Tnp TR:Q9ZG97 (EMBL:AF082836) (444 aa) fasta scores: E(): 1.5e-08, 50% id in 82 aa NP_939133.1 Similar to Methanothermobacter thermautotrophicus hypothetical 11.0 kDa protein MTH1452 TR:O27501 (EMBL:AE000906) (99 aa) fasta scores: E(): 2.8e-10, 41.48% id in 94 aa NP_939134.1 Similar to Mycobacterium tuberculosis hypothetical 29.5 kDa protein Rv2622 or MTCY01A10.10c TR:O06190 (EMBL:Z95387) (273 aa) fasta scores: E(): 2.9e-44, 50.96% id in 259 aa NP_939135.1 Similar to Escherichia coli transposase InsI for insertion sequence element IS30B/C/D (InsI1 or B0256) and (InsI2 or B1404) and (InsI3 or B4284) SW:INSI_ECOLI (P37246) (383 aa) fasta scores: E(): 7.2e-19, 37.94% id in 390 aa NP_939136.1 Similar to Corynebacterium jeikeium transposase A TnpA TR:AAK51146 (EMBL:AY033500) (103 aa) fasta scores: E(): 8.1e-16, 56% id in 100 aa NP_939138.1 Similar to Mycobacterium tuberculosis CDC1551 ATP-dependent DNA helicase, MT0884 TR:AAK45125 (EMBL:AE006976) (542 aa) fasta scores: E(): 1.5e-161, 74.63% id in 544 aa NP_939139.1 Similar to Mycobacterium leprae possible DNA-binding protein ML2156 TR:Q9CBE1 (EMBL:AL583924) (753 aa) fasta scores: E(): 1.2e-60, 33.5% id in 758 aa NP_939140.1 Similar to Mycobacterium leprae hypothetical protein ML2155 TR:Q9CBE2 (EMBL:AL583924) (74 aa) fasta scores: E(): 7.5e-08, 54.09% id in 61 aa NP_939141.1 Similar to Streptomyces coelicolor secreted protein SCE41.06c TR:Q9F2Q2 (EMBL:AL442120) (244 aa) fasta scores: E(): 5.7e-20, 56.3% id in 119 aa NP_939142.1 Similar to Mycobacterium tuberculosis cold shock protein B CspB or Rv0871 or MTV043.64 TR:O53883 (EMBL:AL022004) (135 aa) fasta scores: E(): 8.9e-24, 52.23% id in 134 aa, and to Streptomyces coelicolor cold shock protein B CspB TR:Q9KXN2 (EMBL:AL357524) (127 aa) fasta scores: E(): 1.8e-19, 48.06% id in 129 aa NP_939143.1 Similar to Mycobacterium tuberculosis hypothetical 17.8 kDa protein Rv0875c precursor or MT0898 or MTCY31.03c SW:Y875_MYCTU (Q10537) (162 aa) fasta scores: E(): 6e-05, 25.92% id in 162 aa NP_939144.1 Similar to Deinococcus radiodurans glutamine cyclotransferase DR0112 TR:Q9RY39 (EMBL:AE001874) (294 aa) fasta scores: E(): 1e-28, 40.84% id in 284 aa NP_939145.1 Similar to Mycobacterium leprae hypothetical 28.2 kDa protein ML2142 or MLCB57.29 TR:O33058 (EMBL:Z99494) (269 aa) fasta scores: E(): 5.4e-18, 43.55% id in 225 aa NP_939146.1 Similar to Streptomyces coelicolor integral membrane protein SCD12A.17 TR:Q9KXM3 (EMBL:AL357524) (485 aa) fasta scores: E(): 4.6e-64, 46.04% id in 493 aa NP_939147.1 Similar to Mycobacterium tuberculosis hypothetical tRNA/rRNA methyltransferase Rv0881 or MT0904 or MTCY31.09 SW:Y881_MYCTU (Q10543) (288 aa) fasta scores: E(): 2.5e-52, 53.16% id in 284 aa NP_939149.1 Similar to Mycobacterium leprae hypothetical 27.4 kDa protein ML2137 or MLCB57.36c TR:O33061 (EMBL:Z99494) (251 aa) fasta scores: E(): 1.4e-17, 33.45% id in 284 aa NP_939150.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate NP_939151.2 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH NP_939152.1 Similar to Corynebacterium glutamicum probable FK506-binding protein SW:FKBP_CORGL (P42458) (118 aa) fasta scores: E(): 8.4e-38, 82.05% id in 117 aa, and to Escherichia coli FkbP-type peptidyl-prolyl cis-trans isomerase FkpA precursor or B3347 SW:FKBA_ECOLI (P45523) (270 aa) fasta scores: E(): 2.3e-09, 42.71% id in 103 aa NP_939153.1 Similar to Corynebacterium glutamicum carboxyltransferase subunit of acetyl-CoA carboxylase AccDA TR:CAC42827 (EMBL:Y17592) (491 aa) fasta scores: E(): 8.9e-58, 55.31% id in 499 aa, and to Escherichia coli acetyl-coenzyme A carboxylase carboxyl transferase subunit beta AccD or DedB or Usg or B2316 or Z3578 or ECS3200 SW:ACCD_ECOLI (P08193) (304 aa) fasta scores: E(): 8.6e-22, 34.89% id in 235 aa NP_939154.1 Similar to Streptomyces coelicolor oxidoreductase SC4B5.01c TR:Q9ZBW7 (EMBL:AL034443) (277 aa) fasta scores: E(): 1.3e-48, 48% id in 275 aa, and to Corynebacterium sp 2,5-diketo-D-gluconic acid reductase SW:2DKG_CORSP (P15339) (277 aa) fasta scores: E(): 1.1e-39, 44.52% id in 274 aa NP_939155.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_939156.1 Similar to Streptomyces coelicolor integral membrane protein SCI8.08c TR:Q9RJ45 (EMBL:AL132644) (124 aa) fasta scores: E(): 2.6e-18, 43.63% id in 110 aa NP_939157.1 Similar to Streptomyces coelicolor transmembrane transport protein SCI8.07c TR:Q9RJ46 (EMBL:AL132644) (544 aa) fasta scores: E(): 4.2e-82, 58.31% id in 547 aa NP_939159.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2601 TR:AAK46909 (EMBL:AE007096) (240 aa) fasta scores: E(): 4.3e-31, 46.31% id in 244 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRSFLT) at the N-terminal region NP_939160.1 Similar to Streptomyces coelicolor integral membrane efflux protein SCE39.29 TR:Q9X8F2 (EMBL:AL049573) (404 aa) fasta scores: E(): 7.7e-37, 35.500% id in 400 aa, and to Enterococcus hirae Na(+)/H(+) antiporter NapA SW:NAPA_ENTHR (P26235) (383 aa) fasta scores: E(): 7.5e-12, 21.964% id in 387 aa NP_939162.1 Similar to bacteriophage bIL311 ORF21 TR:Q9AZG0 (EMBL:AF323672) (306 aa) fasta scores: E(): 0.048, 28.030% id in 132 aa NP_939168.1 Similar to bacteriophage bIL311 ORF21 TR:Q9AZG0 (EMBL:AF323672) (306 aa) fasta scores: E(): 0.0075, 25.203% id in 123 aa NP_939171.1 Similar to Haemophilus influenzae type III restriction-modification system HinDVIp enzyme Mod HI1056 SW:T3MH_HAEIN (P71366) (629 aa) fasta scores: E(): 8.3e-26, 29.960% id in 504 aa, and to Lactococcus lactis modification methylase LlaFI Mod TR:Q9Z6H7 (EMBL:AF054600) (680 aa) fasta scores: E(): 5.8e-13, 29.369% id in 412 aa NP_939172.1 Similar to Bacteriophage P1 hypothetical 19.9 kDa protein TR:Q9XJP4 (EMBL:AF137370) (166 aa) fasta scores: E(): 8.2e-09, 28.467% id in 137 aa NP_939181.1 Similar to Mycobacterium tuberculosis probable integrase/recombinase XerC or Rv2894c or MT2962 or MTCY274.25c SW:XERC_MYCTU (Q10815) (298 aa) fasta scores: E(): 3.7, 24.904% id in 261 aa NP_939186.1 catalyzes the formation of precorrin 6x from precorrin 5 NP_939187.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3292 TR:AAK47635 (EMBL:AE007142) (84 aa) fasta scores: E(): 4.4e-12, 48.1% id in 79 aa NP_939188.1 Similar to Mycobacterium avium dihydrofolate reductase FolA TR:O30463 (EMBL:AF006616) (181 aa) fasta scores: E(): 2e-22, 46.1% id in 167 aa, and to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.5e-13, 42.76% id in 152 aa NP_939189.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_939190.1 Similar to Mycobacterium tuberculosis CysQ protein homolog or Rv2131c or MT2189 or MTCY270.37 SW:CYSQ_MYCTU (O06244) (267 aa) fasta scores: E(): 9.2e-23, 52.51% id in 259 aa NP_939191.1 Similar to Escherichia coli probable ATP-dependent helicase Lhr or RhlF or B1653 SW:LHR_ECOLI (P30015) (1538 aa) fasta scores: E(): 1.4e-134, 46.42% id in 1579 aa NP_939192.1 Similar to Streptomyces coelicolor G/U mismatch-specific DNA glycosylase Mug TR:Q9K3I5 (EMBL:AL390188) (160 aa) fasta scores: E(): 1.6e-21, 46.49% id in 157 aa, and to Escherichia coli G/U mismatch-specific DNA glycosylase Mug or B3068 SW:MUG_ECOLI (P43342) (168 aa) fasta scores: E(): 1.1e-15, 36.84% id in 171 aa NP_939193.1 Similar to Streptomyces coelicolor endonuclease VIII Nei or SC7C7.15c SW:END8_STRCO (O86820) (276 aa) fasta scores: E(): 2.5e-39, 40.87% id in 274 aa, and to Escherichia coli endonuclease VIII Nei or B0714 SW:END8_ECOLI (P50465) (262 aa) fasta scores: E(): 4.6e-14, 28.88% id in 277 aa NP_939194.1 Similar to Escherichia coli hypothetical 58.9 kDa protein YidE or B3685 SW:YIDE_ECOLI (P29211) (553 aa) fasta scores: E(): 1.8e-44, 33.21% id in 554 aa NP_939195.1 Similar to Streptomyces coelicolor integral membrane protein SCD39.10 TR:Q9F2V1 (EMBL:AL392146) (138 aa) fasta scores: E(): 8.5e-26, 54.26% id in 129 aa NP_939196.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_939197.1 Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or B2661 SW:GABD_ECOLI (P25526) (482 aa) fasta scores: E(): 2.9e-76, 44.37% id in 471 aa NP_939198.1 Similar to Mycobacterium tuberculosis hypothetical 11.8 kDa protein Rv0948c or MT0975 or MTCY10D7.26 SW:Y948_MYCTU (P71562) (105 aa) fasta scores: E(): 1.6e-14, 62.35% id in 85 aa NP_939199.1 Similar to Mycobacterium leprae ATP-dependent DNA helicase PcrA or UvrD or ML0153 SW:PCRA_MYCLE (Q9CD72) (778 aa) fasta scores: E(): 5.7e-165, 59.08% id in 804 aa, and to Bacillus subtilis ATP-dependent DNA helicase PcrA SW:PCRA_BACSU (O34580) (739 aa) fasta scores: E(): 4.1e-80, 42.76% id in 802 aa NP_939200.1 Similar to C-terminal region of Mycobacterium tuberculosis CDC1551 peptidase, M23/M37 family MT0977 TR:AAK45225 (EMBL:AE006983) (332 aa) fasta scores: E(): 2.2e-33, 45.25% id in 232 aa NP_939201.1 Low similarity to Mycobacterium tuberculosis hypothetical 46.1 kDa protein Rv0955 or MT0982 or MTCY10D7.19c SW:Y955_MYCTU (P71555) (455 aa) fasta scores: E(): 1.9e-17, 28.01% id in 439 aa NP_939202.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate NP_939203.1 involved in de novo purine biosynthesis NP_939204.1 No significant database matches. Similar to CDS downstream DIP0841 38.272% identity in 162 aa overlap NP_939205.1 No significant database matches. Similar to CDS upstream DIP0840 38.272% identity in 162 aa overlap NP_939207.1 Similar to Escherichia coli possible transposase of IS1353 YahA SWALL:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 8.7e-62, 41.25% id in 463 aa NP_939209.1 Similar to Mycobacterium tuberculosis CDC1551 citrate lyase, beta subunit MT2573 TR:AAK46877 (EMBL:AE007094) (273 aa) fasta scores: E(): 9.7e-35, 42.42% id in 264 aa, and to Escherichia coli citrate lyase beta chain CitE or B0616 SW:CILB_ECOLI (P77770) (302 aa) fasta scores: E(): 1.8e-06, 25.83% id in 298 aa NP_939210.1 Similar to Corynebacterium glutamicum AmtR protein TR:Q9S3L4 (EMBL:AJ133719) (222 aa) fasta scores: E(): 9.6e-59, 70.18% id in 218 aa NP_939212.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_939213.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_939214.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_939215.1 required for 70S ribosome assembly NP_939216.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_939217.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_939218.1 Similar to Corynebacterium glutamicum response regulator TR:Q9F161 (EMBL:AF119221) (232 aa) fasta scores: E(): 2.4e-67, 79.31% id in 232 aa, and to Pseudomonas syringae transcriptional activator protein CopR SW:COPR_PSESM (Q02540) (227 aa) fasta scores: E(): 1.9e-32, 48% id in 225 aa NP_939219.1 Similar to Corynebacterium glutamicum sensor kinase TR:Q9F160 (EMBL:AF119221) (455 aa) fasta scores: E(): 6.5e-71, 46.98% id in 447 aa, and to Burkholderia pseudomallei sensor protein IrlS SW:IRLS_BURPS (O31396) (464 aa) fasta scores: E(): 4.6e-18, 26% id in 446 aa NP_939220.1 Similar to Mycobacterium tuberculosis serine protease Rv0983 or MTV044.11 SWALL:O53896 (EMBL:AL021999) (464 aa) fasta scores: E(): 3.8e-46, 43.84% id in 406 aa, and to Brucella abortus probable serine protease do-like precursor DegP or HtrA SWALL:DEGP_BRUAB (SWALL:Q44597) (513 aa) fasta scores: E(): 7.6e-25, 44.56% id in 285 aa NP_939221.1 Similar to Mycobacterium leprae molybdenum cofactor biosynthesis protein MoaB or ML0177 or MLCB373.29 TR:Q9Z5G5 (EMBL:AL035500) (181 aa) fasta scores: E(): 8.3e-28, 60% id in 150 aa NP_939222.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939223.1 Similar to Mycobacterium tuberculosis large-conductance mechanosensitive channel MscL or Rv0985c or MT1013 or MTV044.13c SW:MSCL_MYCTU (O53898) (151 aa) fasta scores: E(): 3e-16, 48.5% id in 134 aa, and to Escherichia coli, and large-conductance mechanosensitive channel MscL or B3291 or Z4661 or ECS4156 SW:MSCL_ECOLI (P23867) (136 aa) fasta scores: E(): 9.2e-11, 41.3% id in 138 aa NP_939225.1 Similar to Mycobacterium leprae hypothetical 21.3 kDa protein ML0181 or MLCB373.33c TR:Q9Z5G2 (EMBL:AL035500) (197 aa) fasta scores: E(): 2.1e-14, 34.73% id in 190 aa NP_939226.1 Similar to Mycobacterium tuberculosis CDC1551 UTP--glucose-1-phosphate uridylyltransferase MT1022 TR:AAK45269 (EMBL:AE006986) (306 aa) fasta scores: E(): 3.2e-65, 64.8% id in 287 aa, and to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SW:GTAB_BACSU (Q05852) (292 aa) fasta scores: E(): 1.4e-32, 40.67% id in 295 aa NP_939227.1 Similar to Mycobacterium tuberculosis molybdopterin biosynthesis protein MoeA or Rv0994 or MT1023 or MTCI237.08 SW:MOEA_MYCTU (O05577) (426 aa) fasta scores: E(): 1.1e-89, 58.35% id in 425 aa, and to Escherichia coli molybdopterin biosynthesis protein MoeA or ChlE or BisB or NarE or B0827 SW:MOEA_ECOLI (P12281) (411 aa) fasta scores: E(): 1.1e-17, 29.58% id in 409 aa NP_939228.1 Similar to Mycobacterium leprae possible acetyltransferase RimJ or ML0184 TR:Q9CD65 (EMBL:AL583917) (214 aa) fasta scores: E(): 3.6e-35, 47.03% id in 202 aa NP_939229.1 Similar to Mycobacterium tuberculosis hypothetical 39.5 kDa protein Rv0996 or MTCI237.10 TR:O05579 (EMBL:Z94752) (358 aa) fasta scores: E(): 1.8e-13, 30.27% id in 370 aa NP_939230.1 Similar to Mycobacterium leprae integral membrane protein ML0956 TR:Q9CCC8 (EMBL:AL583920) (169 aa) fasta scores: E(): 2.1e-11, 39.51% id in 124 aa NP_939232.1 Similar to Mycobacterium leprae membrane protein ML0192 TR:Q9CD61 (EMBL:AL583917) (510 aa) fasta scores: E(): 8e-80, 42.74% id in 496 aa NP_939233.1 Similar to Corynebacterium glutamicum glycine betaine transporter BetP SW:BETP_CORGL (P54582) (595 aa) fasta scores: E(): 7.8e-154, 70.87% id in 563 aa, and to Bacillus subtilis glycine betaine transporter OpuD SW:OPUD_BACSU (P54417) (512 aa) fasta scores: E(): 1.1e-76, 43.52% id in 517 aa NP_939234.1 Similar to Staphylococcus aureus (strain N315) hypothetical protein SA2305 or SAV2517 TR:BAB58679 (EMBL:AP003137) (359 aa) fasta scores: E(): 1.3e-35, 32.55% id in 344 aa NP_939235.1 Similar to Mycobacterium tuberculosis hypothetical 29.7 kDa protein Rv1003 or MT1032 or MTCI237.19 SW:YA03_MYCTU (O05588) (285 aa) fasta scores: E(): 2.1e-51, 58.54% id in 275 aa NP_939236.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_939237.1 Similar to Corynebacterium glutamicum Mg-dependent DNAse CGL0908 SWALL:Q8NRY3 (EMBL:AP005276) (277 aa) fasta scores: E(): 3.7e-81, 73.74% id in 278 aa, and to Mycobacterium tuberculosis hypothetical protein Ycfh Rv1008 or MTCI237.25 TR:O08343 (EMBL:Z94752) (264 aa) fasta scores: E(): 4.4e-40, 44.61% id in 260 aa NP_939238.1 Similar to Mycobacterium tuberculosis hypothetical 38.1 kDa protein Rv1009 or MTCI237.26 TR:O05594 (EMBL:Z94752) (362 aa) fasta scores: E(): 1.8e-39, 38.71% id in 372 aa NP_939239.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_939240.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis NP_939241.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding subunit SCE66.26c TR:Q9K3R7 (EMBL:AL359989) (604 aa) fasta scores: E(): 2.3e-97, 54.75% id in 610 aa NP_939242.1 Similar to Mycobacterium tuberculosis hypothetical 12.0 kDa protein Rv1117 or MTCY22G8.06 TR:O06569 (EMBL:Z95585) (107 aa) fasta scores: E(): 3.6e-13, 43.92% id in 107 aa NP_939244.1 Similar to Xanthomonas campestris probable RNA polymerase sigma factor RfaY SW:RFAY_XANCP (P46358) (217 aa) fasta scores: E(): 9.8e-07, 32.88% id in 149 aa NP_939246.1 Similar to Mycobacterium tuberculosis CDC1551 RNA polymerase sigma factor, MT3329 TR:AAK47672 (EMBL:AE007144) (295 aa) fasta scores: E(): 1.4e-68, 61.42% id in 280 aa, and to Pseudomonas aeruginosa pao substrain OT684 pyoverdine gene transcriptional regulator PvdS TR:P72119 (EMBL:U12891) (237 aa) fasta scores: E(): 5.9e-56, 59.91% id in 237 aa NP_939247.1 Low similarity to Escherichia coli protein PnuC or B0751 SW:PNUC_ECOLI (P31215) (239 aa) fasta scores: E(): 5e-07, 23.75% id in 240 aa NP_939248.1 Similar to Streptococcus pyogenes hypothetical protein SPY0567 TR:Q9A0X9 (EMBL:AE006513) (265 aa) fasta scores: E(): 6.5e-20, 32.31% id in 263 aa NP_939249.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA NP_939251.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939252.1 Similar to Streptomyces coelicolor tetR-family transcriptional regulator SCF56.06 TR:Q9RD60 (EMBL:AL133424) (213 aa) fasta scores: E(): 2.9e-07, 40.51% id in 116 aa NP_939253.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939254.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939255.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent NP_939257.1 Low similarity to Arabidopsis thaliana AT2G37870 protein or T8P21.22 TR:Q9SHA0 (EMBL:AC007661) (115 aa) fasta scores: E(): 6.8, 31.66% id in 60 aa NP_939258.1 Similar to Caulobacter crescentus peptide chain release factor 3 CC1070 TR:Q9A9B9 (EMBL:AE005784) (534 aa) fasta scores: E(): 2.4e-70, 40% id in 545 aa, and to Staphylococcus aureus peptide chain release factor 3 PrfC or Rf3 SW:RF3_STAAU (O86490) (521 aa) fasta scores: E(): 2e-38, 38.57% id in 547 aa, and to Escherichia coli peptide chain release factor 3 PrfC or Tos or MiaD or B4375 or Z5976 or ECS5333 SW:RF3_ECOLI (P33998) (528 aa) fasta scores: E(): 1.6e-24, 41.94% id in 534 aa NP_939259.1 Similar to Streptomyces peucetius daunorubicin C-13 ketoreductase DnrU TR:Q9ZAU1 (EMBL:U77891) (287 aa) fasta scores: E(): 1.3e-16, 35.25% id in 278 aa NP_939260.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_939262.1 Low similarity to parts of Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0103 TR:AAK44326 (EMBL:AE006921) (287 aa) fasta scores: E(): 5.6e-09, 39.04% id in 105 aa NP_939263.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_939264.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_939265.1 Similar to the C-terminal regions of Thermotoga maritima pullulanase precursor PulA or TM1845 SW:PULA_THEMA (O33840) (843 aa) fasta scores: E(): 3.3e-67, 36.72% id in 610 aa, and of Klebsiella pneumoniae pullulanase precursor PulA SW:PULA_KLEPN (P07206) (1090 aa) fasta scores: E(): 1.2e-20, 28.94% id in 615 aa NP_939266.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_939267.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_939268.1 Similar to Pseudomonas aeruginosa probable transcriptional regulator PA3398 TR:Q9HYK6 (EMBL:AE004761) (308 aa) fasta scores: E(): 4e-18, 30.94% id in 265 aa NP_939269.1 Low similarity to Streptomyces coelicolor integral membrane protein SCI35.39 TR:O88074 (EMBL:AL031541) (394 aa) fasta scores: E(): 1.8e-16, 29.34% id in 351 aa NP_939270.1 Similar to Corynebacterium glutamicum hypothetical 33.0 kDa protein in proB-proA intergenic region SW:YPRA_CORGL (P45637) (304 aa) fasta scores: E(): 7.5e-48, 45.3% id in 309 aa, and to Escherichia coli 2-ketogluconate reductase TkrA or B3553 SW:TKRA_ECOLI (P37666) (324 aa) fasta scores: E(): 1.4e-13, 31.57% id in 247 aa NP_939271.1 Similar to Corynebacterium striatum ABC transporter TetA TR:Q9Z4Q1 (EMBL:U21300) (513 aa) fasta scores: E(): 1.3e-45, 33.98% id in 509 aa NP_939272.1 Similar to C-terminal region of Mycobacterium smegmatis ExiT TR:O85018 (EMBL:AF034152) (1122 aa) fasta scores: E(): 5.9e-45, 34.56% id in 596 aa, and to Streptomyces coelicolor ABC-transporter transmembrane protein SCF34.12c TR:Q9RK13 (EMBL:AL109974) (601 aa) fasta scores: E(): 1.5e-42, 33.98% id in 612 aa NP_939273.1 Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, tetR family MT1047 TR:AAK45298 (EMBL:AE006987) (202 aa) fasta scores: E(): 4.4e-45, 63.9% id in 205 aa NP_939274.1 Similar to Mycobacterium tuberculosis transcription-repair coupling factor Mfd or Rv1020 or MT1048 or MTCY10G2.29c SW:MFD_MYCTU (P96380) (1234 aa) fasta scores: E(): 2e-200, 57.37% id in 1234 aa, and to Escherichia coli transcription-repair coupling factor Mfd or B1114 SW:MFD_ECOLI (P30958) (1148 aa) fasta scores: E(): 7e-103, 36.52% id in 1191 aa NP_939277.1 Similar to Corynebacterium glutamicum L-Lysine transport protein LysI SW:LYSI_CORGL (P35865) (501 aa) fasta scores: E(): 9.3e-131, 69.85% id in 491 aa NP_939278.1 Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv1021 or MTCY10G2.28c TR:P96379 (EMBL:Z92539) (325 aa) fasta scores: E(): 3.2e-20, 38.61% id in 202 aa NP_939279.1 Similar to Mycobacterium tuberculosis hypothetical 25.8 kDa protein LpqU or Rv1022 or MTCY10G2.27c TR:P96378 (EMBL:Z92539) (243 aa) fasta scores: E(): 7.2e-34, 46.02% id in 239 aa NP_939280.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_939281.1 Similar to Mycobacterium tuberculosis hypothetical 24.6 kDa protein Rv1024 or MTCY10G2.25c TR:P96376 (EMBL:Z92539) (228 aa) fasta scores: E(): 1.5e-08, 31.21% id in 157 aa NP_939282.1 Similar to Mycobacterium leprae hypothetical protein ML0257 TR:Q9CD40 (EMBL:AL583917) (167 aa) fasta scores: E(): 4e-33, 59.49% id in 158 aa NP_939283.1 Similar to Mycobacterium leprae hypothetical 33.5 kDa protein ML0258 or MLCB4.02 TR:O69585 (EMBL:AL023514) (317 aa) fasta scores: E(): 9e-53, 52.56% id in 312 aa NP_939285.1 Similar to Pseudomonas aeruginosa probable transcriptional regulator PA2488 TR:Q9I0Z4 (EMBL:AE004676) (254 aa) fasta scores: E(): 5.9e-10, 34.66% id in 150 aa, and to Streptomyces coelicolor araC-family transcriptional regulator SC9H11.05 TR:Q9KYN4 (EMBL:AL356592) (289 aa) fasta scores: E(): 3.3e-05, 29.49% id in 217 aa NP_939286.1 Similar to Mycobacterium tuberculosis transmembrane protein Rv1072 or MTV017.25 TR:O53420 (EMBL:AL021897) (278 aa) fasta scores: E(): 2.4e-47, 58.21% id in 280 aa NP_939288.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_939289.1 Similar to Mycobacterium leprae conserved membrane protein ML2392 TR:Q9CB66 (EMBL:AL583925) (144 aa) fasta scores: E(): 6.2e-10, 33.56% id in 143 aa NP_939290.1 Similar to Mycobacterium leprae LmbE (hypothetical protein ML2391) TR:Q50060 (EMBL:U15183) (290 aa) fasta scores: E(): 9e-62, 55.17% id in 290 aa NP_939292.1 Similar to Mycobacterium leprae possible undecaprenyl pyrophosphate synthetase ML2467 TR:Q9CB36 (EMBL:AL583925) (262 aa) fasta scores: E(): 4.1e-57, 60% id in 250 aa, and to Bacillus subtilis undecaprenyl pyrophosphate synthetase UppS SW:UPPS_BACSU (O31751) (260 aa) fasta scores: E(): 2.1e-26, 36.84% id in 247 aa NP_939294.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_939295.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_939296.1 Similar to Streptomyces coelicolor hypothetical 14.7 kDa protein 2SCG38.16 TR:Q9EX03 (EMBL:AL445503) (132 aa) fasta scores: E(): 1.2e-18, 53.39% id in 103 aa NP_939297.1 Low similarity to Streptomyces coelicolor regulatory protein 2SCG38.15c TR:Q9EX04 (EMBL:AL445503) (278 aa) fasta scores: E(): 2.1e-10, 28.39% id in 236 aa NP_939298.1 Similar to Alcaligenes faecalis phosphinothricin N-acetyltransferase Bar SW:PAT_ALCFA (P31668) (197 aa) fasta scores: E(): 7.8e-08, 31.176% identity in 170 aa overlap and to Streptomyces coelicolor phosphinothricin N-acetyltransferase Bar or SCE22.20 SW:PAT_STRCO (P21861) (171 aa) fasta scores: E(): 5.3e-07, 25.56% id in 176 aa NP_939299.1 Similar to Streptomyces coelicolor integral membrane transport protein SCC8A.02c TR:Q9KY46 (EMBL:AL356892) (689 aa) fasta scores: E(): 8.5e-70, 42.83% id in 523 aa, and to Mycobacterium tuberculosis CDC1551 drug transporter MT1926 TR:AAK46198 (EMBL:AE007049) (687 aa) fasta scores: E(): 1.1e-57, 37.45% id in 518 aa NP_939300.1 Similar to Streptomyces coelicolor tetR-family transcriptional regulator SCF56.06 TR:Q9RD60 (EMBL:AL133424) (213 aa) fasta scores: E(): 4.4e-06, 35.59% id in 118 aa NP_939301.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle NP_939302.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese NP_939303.1 Low similarity to Mycobacterium tuberculosis hypothetical 24.6 kDa protein Rv1100 or MTV017.53 TR:O53448 (EMBL:AL021897) (233 aa) fasta scores: E(): 8e-06, 28.92% id in 204 aa NP_939304.1 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_939305.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_939306.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_939308.1 Similar to Streptomyces coelicolor integral membrane protein SCF6.09 TR:Q9RJL9 (EMBL:AL121849) (363 aa) fasta scores: E(): 2e-46, 44.73% id in 342 aa, and to Escherichia coli permease perm PerM or B2493 or Z3755 or ECS3355 SW:PERM_ECOLI (P77406) (353 aa) fasta scores: E(): 4.7e-17, 29.2% id in 339 aa NP_939310.1 Similar to Pasteurella multocida hypothetical protein PM0718 TR:Q9CMU0 (EMBL:AE006109) (502 aa) fasta scores: E(): 6.7e-106, 57.72% id in 492 aa, and to Haemophilus influenzae hypothetical sodium-dependent transporter HI0736 SW:Y736_HAEIN (P44849) (508 aa) fasta scores: E(): 2.9e-104, 55.17% id in 502 aa NP_939311.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_939312.1 Similar to Deinococcus radiodurans conserved hypothetical protein DR1297 TR:Q9RUT5 (EMBL:AE001977) (311 aa) fasta scores: E(): 2.2e-57, 51.92% id in 312 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3176.1 TR:AAK47515 (EMBL:AE007134) (306 aa) fasta scores: E(): 5.1e-55, 54.54% id in 297 aa NP_939313.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_939314.1 Similar to Bacillus subtilis YkoE TR:O34738 (EMBL:AJ002571) (199 aa) fasta scores: E(): 5.8e-16, 39.36% id in 188 aa NP_939315.1 Similar to Neisseria meningitidis chloride channel protein-related protein NMB0982 TR:Q9JZM8 (EMBL:AE002449) (380 aa) fasta scores: E(): 1.4e-21, 31.25% id in 352 aa NP_939316.1 Similar to Staphylococcus aureus (strain N315) SA0928 protein or SAV1076 TR:BAB57238 (EMBL:AP003132) (466 aa) fasta scores: E(): 6.9e-32, 34.18% id in 433 aa NP_939317.1 Low similarity to Bacillus subtilis YkoC TR:O34572 (EMBL:AJ002571) (254 aa) fasta scores: E(): 1.3e-06, 24.48% id in 241 aa NP_939319.1 Similar to Corynebacterium glutamicum ABC-type transporter, periplasmic component CGL1990 SWALL:Q8NP35 (EMBL:AP005280) (534 aa) fasta scores: E(): 7.8e-143, 66.79% id in 533 aa, and to Mycobacterium tuberculosis peptide transport system secreted peptide-binding protein Rv3666c or MTV025.014c or MT3767 SWALL:O69634 (EMBL:AL022121) (541 aa) fasta scores: E(): 6.8e-75, 49.06% id in 534 aa, and to Bacillus subtilis dipeptide-binding protein precursor DppE or DciAE SWALL:DPPE_BACSU (SWALL:P26906) (543 aa) fasta scores: E(): 1.2e-18, 24.49% id in 539 aa NP_939320.1 Similar to Mycobacterium tuberculosis peptide transport system permease Rv3665c or MTV025.013c TR:O69633 (EMBL:AL022121) (308 aa) fasta scores: E(): 4.9e-69, 63.48% id in 304 aa, and to Bacillus subtilis oligopeptide transport system permease OppB or Spo0KB SW:OPPB_BACSU (P24138) (311 aa) fasta scores: E(): 1.8e-37, 37.33% id in 308 aa, and to Corynebacterium glutamicum ABC-type transporter, permease components CGL1991 SWALL:Q8NP34 (EMBL:AP005280) (308 aa) fasta scores: E(): 1.5e-95, 84.09% id in 308 aa NP_939321.1 Similar to Streptomyces coelicolor peptide transport system integral membrane protein SC9E12.04 TR:Q9F351 (EMBL:AL391751) (305 aa) fasta scores: E(): 1.2e-56, 50.86% id in 289 aa, and to Bacillus subtilis oligopeptide transport system permease OppC or Spo0KC SW:OPPC_BACSU (P24139) (305 aa) fasta scores: E(): 5.5e-35, 36.86% id in 293 aa, and to Corynebacterium glutamicum ABC-type transporter, permease components CGL1992 SWALL:Q8NP33 (EMBL:AP005280) (333 aa) fasta scores: E(): 2.4e-98, 80.32% id in 310 aa NP_939322.1 Similar in its full length to Mycobacterium tuberculosis peptide ABC transporter ATP-binding protein Rv3663c or MTV025.011c TR:O69631 (EMBL:AL022121) (548 aa) fasta scores: E(): 4.5e-100, 58.27% id in 544 aa, and N-terminal region and C-termianl region both similar to Bacillus subtilis oligopeptide transport ATP-binding protein OppD or Spo0KD SW:OPPD_BACSU (P24136) (358 aa) fasta scores: E(): 3.1e-38, 46.56% id in 262 aa NP_939324.1 Similar to Bacillus subtilis homologous to many ATP-binding transport proteins YxlF TR:P94374 (EMBL:D83026) (295 aa) fasta scores: E(): 6.4e-12, 31.22% id in 221 aa, and to Escherichia coli, and aliphatic sulfonates transport ATP-binding protein SsuB or B0933 or Z1281 or ECS1016 SW:SSUB_ECOLI (P38053) (255 aa) fasta scores: E(): 3.3e-08, 31.25% id in 208 aa NP_939327.1 Similar to Streptomyces coelicolor hydrolase SCBAC14E8.01c TR:Q9ADJ8 (EMBL:AL590435) (228 aa) fasta scores: E(): 0.0013, 30.47% id in 233 aa NP_939328.1 Similar to Escherichia coli arsenate reductase ArsC or ArsG or B3503 SW:ARSC_ECOLI (P37311) (141 aa) fasta scores: E(): 1.8e-14, 48.24% id in 114 aa NP_939329.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 16.6 kDa protein MT1668 TR:AAK45938 (EMBL:AE007030) (147 aa) fasta scores: E(): 1.1e-16, 39.43% id in 142 aa NP_939330.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 36.6 kDa protein MT1193 TR:AAK45450 (EMBL:AE006997) (371 aa) fasta scores: E(): 7.8e-15, 33.91% id in 230 aa NP_939331.1 Similar to Mycobacterium tuberculosis CDC1551 GTP-binding elongation factor family protein MT1202 TR:AAK45459 (EMBL:AE006997) (628 aa) fasta scores: E(): 6.7e-148, 67.88% id in 629 aa, and to Escherichia coli GTP-binding protein TypA/BipA TypA or BipA or B3871 SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 3.3e-58, 46.49% id in 613 aa NP_939332.1 Similar to Mycobacterium tuberculosis hypothetical 66.1 kDa protein LpqW or Rv1166 or MTV005.02 TR:O50422 (EMBL:AL010186) (635 aa) fasta scores: E(): 4.6e-29, 32.02% id in 381 aa NP_939333.1 Similar to Mycobacterium tuberculosis hypothetical 31.7 kDa protein Rv1170 or MTV005.06 TR:O50426 (EMBL:AL010186) (303 aa) fasta scores: E(): 3.9e-27, 40.34% id in 290 aa NP_939335.1 Highly similar to Saccharopolyspora erythraea ferredoxin FdxA SW:FER_SACER (P24496) (105 aa) fasta scores: E(): 9.3e-32, 76.69% id in 103 aa NP_939336.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis NP_939337.1 Similar to, although shorter than, Mycobacterium tuberculosis CDC1551 RNA pseudouridylate synthase MT3399 TR:AAK47742 (EMBL:AE007148) (305 aa) fasta scores: E(): 3.5e-23, 37.33% id in 233 aa, and similar to Escherichia coli ribosomal large subunit pseudouridine synthase A RluR or B0058 SW:RLUA_ECOLI (P39219) (218 aa) fasta scores: E(): 1.8e-07, 26.76% id in 213 aa NP_939340.1 Similar to Corynebacterium glutamicum aromatic amino acid transport protein AroP SW:AROP_CORGL (Q46065) (463 aa) fasta scores: E(): 1.1e-91, 56.16% id in 454 aa. Possible duplication of DIP0980 (57.395% identity in 453 aa overlap) NP_939341.1 Similar to Mycobacterium tuberculosis CDC1551 tetrahydrodipicolinate N-succinyltransferase, MT1239 TR:AAK45496 (EMBL:AE007001) (317 aa) fasta scores: E(): 1.4e-70, 66.35% id in 324 aa, and to Vibrio cholerae 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase VC2329 TR:Q9KPN7 (EMBL:AE004303) (343 aa) fasta scores: E(): 3e-53, 52.16% id in 347 aa. Similar also to DIP0981 (45.614% identity in 285 aa overlap) NP_939342.1 Similar to Corynebacterium glutamicum aromatic amino acid transport protein AroP SW:AROP_CORGL (Q46065) (463 aa) fasta scores: E(): 6.2e-118, 74.27% id in 447 aa, and to Escherichia coli gaba permease GabP or B2663 SW:GABP_ECOLI (P25527) (466 aa) fasta scores: E(): 6.2e-59, 41.03% id in 446 aa. Possible duplication of DIP0978 (57.395% identity in 453 aa overlap) NP_939343.1 Similar to Mycobacterium tuberculosis CDC1551 tetrahydrodipicolinate N-succinyltransferase, MT1239 TR:AAK45496 (EMBL:AE007001) (317 aa) fasta scores: E(): 3.2e-46, 46.53% id in 303 aa, and C-terminal region to Corynebacterium glutamicum tetrahydrodipicolinate succinylase DapD TR:O69283 (EMBL:AJ004934) (230 aa) fasta scores: E(): 1.6e-28, 45.2% id in 219 aa. Similar also to DIP0979 (45.614% identity in 285 aa overlap) NP_939344.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate NP_939345.1 Similar in its N-terminal region to Corynebacterium glutamicum ORF2 protein TR:Q46063 (EMBL:X81379) (211 aa) fasta scores: E(): 2.5e-63, 76.66% id in 210 aa, and to Streptomyces coelicolor hypothetical 27.5 kDa protein SCP8.03 TR:Q9FBL8 (EMBL:AL390975) (252 aa) fasta scores: E(): 7.5e-60, 64.08% id in 245 aa NP_939346.1 Similar to Mycobacterium leprae dihydropteroate synthase FolP1 or FolP or ML0224 and FolP2 or ML1063 SW:DHPS_MYCLE (P46812) (291 aa) fasta scores: E(): 4.8e-57, 58.69% id in 276 aa, and to Escherichia coli dihydropteroate synthase FolP or DhpS or B3177 SW:DHPS_ECOLI (P26282) (282 aa) fasta scores: E(): 1.2e-25, 35.79% id in 257 aa NP_939347.1 Similar to Streptomyces coelicolor hypothetical 34.0 kDa protein SCD95A.25c TR:Q9KXU9 (EMBL:AL357432) (314 aa) fasta scores: E(): 2.9e-29, 47.67% id in 258 aa, and to Methanothermobacter thermautotrophicus dolichyl-phosphate mannose synthase related protein MTH374 TR:O26474 (EMBL:AE000823) (291 aa) fasta scores: E(): 1.4e-08, 31.89% id in 254 aa NP_939348.1 Similar to, although shorter than, Streptomyces coelicolor secreted protein SCP8.05 TR:Q9FBL6 (EMBL:AL390975) (119 aa) fasta scores: E(): 1.1, 32.09% id in 81 aa NP_939349.1 Similar to C-terminal region of Streptomyces coelicolor conserved hypothetical protein SCP8.08 TR:Q9FBL3 (EMBL:AL390975) (74 aa) fasta scores: E(): 8.5e-11, 60.37% id in 53 aa NP_939350.1 Similar to Micromonospora griseorubida mycinamicin-resistance protein MyrA SW:MYRA_MICGR (P37000) (295 aa) fasta scores: E(): 2.8e-31, 39.51% id in 286 aa, and to Streptomyces fradiae tylosin resistance protein TlrB TR:Q9ZHQ6 (EMBL:AF055922) (280 aa) fasta scores: E(): 2.4e-30, 37.82% id in 267 aa NP_939351.1 Similar to the N-terminal region of Pichia jadinii beta-D-fructofuranoside fructohydrolase Inv1 TR:O94224 (EMBL:Y12659) (533 aa) fasta scores: E(): 1.5e-09, 26.33% id in 300 aa, and to the C-terminal region of Pseudomonas mucidolens endo-inulinase TR:Q9RGC0 (EMBL:AF141320) (776 aa) fasta scores: E(): 3.6e-07, 21.77% id in 473 aa NP_939352.1 Similar to Bacillus subtilis alpha-acetolactate decarboxylase AlsD SW:ALDC_BACSU (Q04777) (255 aa) fasta scores: E(): 2.1e-38, 44.78% id in 230 aa NP_939353.1 Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT1250 TR:AAK45507 (EMBL:AE007001) (387 aa) fasta scores: E(): 2.9e-91, 60.72% id in 387 aa, and to Bacillus subtilis spore coat protein SA CotSA SW:CTSA_BACSU (P46915) (377 aa) fasta scores: E(): 1.6e-13, 24.37% id in 402 aa NP_939354.2 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate NP_939355.1 Similar to Mycobacterium tuberculosis CDC1551 O-methyltransferase MT1258 TR:AAK45515 (EMBL:AE007002) (215 aa) fasta scores: E(): 6e-17, 37.91% id in 182 aa NP_939356.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence NP_939357.1 Similar to Mycobacterium leprae hypothetical protein ML1077 TR:Q9CCA5 (EMBL:AL583920) (139 aa) fasta scores: E(): 8e-09, 40.35% id in 114 aa NP_939358.1 Similar to Streptomyces lividans twin arginine translocation complex component TatB TR:Q9EWB3 (EMBL:AJ292256) (158 aa) fasta scores: E(): 1.8e-05, 28.88% id in 135 aa, and to Escherichia coli Sec-independent protein translocase TatB or MttA2 or B3838 or Z5359 or ECS4767 SW:TATB_ECOLI (O69415) (171 aa) fasta scores: E(): 0.0023, 29.33% id in 150 aa NP_939359.1 Similar to Mycobacterium tuberculosis Mrp protein homolog or Rv1229c or MT1267 or MTCI61.12c or MTV006.01c SW:MRP_MYCTU (O33225) (381 aa) fasta scores: E(): 1.4e-84, 65.21% id in 368 aa NP_939360.1 Similar to Mycobacterium tuberculosis hypothetical 20.4 kDa protein Rv1231c or MTV006.03c TR:O86314 (EMBL:Z98260) (180 aa) fasta scores: E(): 4.5e-31, 60.81% id in 148 aa NP_939361.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 47.3 kDa protein MT1270 TR:AAK45528 (EMBL:AE007003) (435 aa) fasta scores: E(): 5e-77, 52.51% id in 417 aa NP_939362.1 Similar to Mycobacterium tuberculosis hypothetical 18.6 kDa protein Rv1234 or MTV006.06 TR:O50451 (EMBL:AL021006) (175 aa) fasta scores: E(): 2.9e-27, 56.42% id in 140 aa NP_939363.1 no database matches NP_939364.2 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth NP_939365.1 Similar to Streptomyces coelicolor ABC transporter protein, ATP-binding component SCC57A.34c TR:Q9RDG5 (EMBL:AL136519) (1243 aa) fasta scores: E(): 3e-116, 42.18% id in 1247 aa NP_939366.1 Similar to Mycobacterium tuberculosis hypothetical 27.6 kDa protein Rv1249c or MTV006.21c TR:O50464 (EMBL:AL021006) (262 aa) fasta scores: E(): 2.1e-15, 31.57% id in 209 aa NP_939367.1 Similar to part of Mycobacterium smegmatis IS1096 TnpA protein TR:Q50440 (EMBL:M76495) (413 aa) fasta scores: E(): 0.7, 29.47% id in 95 aa NP_939368.1 catalyzes the conversion of shikimate to 3-dehydroshikimate NP_939369.1 Similar to Bacillus spBP-7. type B carboxylesterase EstA1 TR:Q9L378 (EMBL:AJ278066) (486 aa) fasta scores: E(): 3.2e-47, 34% id in 500 aa, and to Bacillus subtilis para-nitrobenzyl esterase PnbA SW:PNBA_BACSU (P37967) (489 aa) fasta scores: E(): 3.3e-49, 33.93% id in 501 aa NP_939373.1 Similar to aldose 1-epimerases e.g. Escherichia coli O157:H7 aldose-1-epimerase ECS4802 TR:BAB38225 (EMBL:AP002567) (300 aa) fasta scores: E(): 3.1e-21, 29.09% id in 299 aa, and to Escherichia coli hypothetical protein YihR or B3879 SW:YIHR_ECOLI (P32139) (308 aa) fasta scores: E(): 7.7e-21, 30.35% id in 280 aa, and to Salmonella typhimurium aldose-1-epimerase YihR TR:Q9L7R7 (EMBL:AF220438) (280 aa) fasta scores: E(): 1.1e-13, 29.53% id in 281 aa. Contains weak match to PFAM:PF01263 Aldose 1-epimerase E: 0.089 NP_939374.1 Similar to Streptomyces coelicolor sodium:solute symporter SCE66.18 TR:Q9K3S5 (EMBL:AL359989) (562 aa) fasta scores: E(): 7e-115, 56.42% id in 553 aa, and to Rattus norvegicus sodium-dependent multivitamin transporter slc5a6 or smvT SW:SL56_RAT (O70247) (634 aa) fasta scores: E(): 3.3e-23, 24.2% id in 504 aa NP_939375.1 Similar to Streptomyces coelicolor membrane protein SCE66.19 TR:Q9K3S4 (EMBL:AL359989) (98 aa) fasta scores: E(): 6.7e-06, 46.15% id in 65 aa NP_939376.1 Similar to Escherichia coli galactose-1-phosphate uridylyltransferase GalT or GalB or B0758 SW:GAL7_ECOLI (P09148) (348 aa) fasta scores: E(): 1.2e-24, 30.34% id in 346 aa, and to Streptomyces lividans galactose-1-phosphate uridylyltransferase GalT SW:GAL7_STRLI (P13212) (354 aa) fasta scores: E(): 4.9e-30, 38.8% id in 384 aa, and to Homo sapiens galactose-1-phosphate uridylyltransferase GalT SW:GAL7_HUMAN (P07902) (379 aa) fasta scores: E(): 8.1e-29, 33.82% id in 340 aa NP_939377.1 Similar to Streptomyces lividans galactokinase GalK SW:GAL1_STRLI (P13227) (397 aa) fasta scores: E(): 1.3e-27, 36.45% id in 384 aa, and to Homo sapiens galactokinase GalK1 or GalK SW:GAL1_HUMAN (P51570) (392 aa) fasta scores: E(): 3e-23, 38.29% id in 410 aa, and to Escherichia coli galactokinase GalK or GalA or B0757 or Z0927 or ECS0785 SW:GAL1_ECOLI (P06976) (381 aa) fasta scores: E(): 1e-11, 32.08% id in 399 aa NP_939378.1 Similar to Streptomyces coelicolor helicase SCE20.37 TR:Q9RD88 (EMBL:AL136058) (945 aa) fasta scores: E(): 5.3e-162, 46.4% id in 933 aa, and to Vibrio cholerae helicase-related protein VC0812 TR:Q9KTS6 (EMBL:AE004166) (979 aa) fasta scores: E(): 3.5e-48, 31.6% id in 674 aa NP_939379.1 Similar to Staphylococcus aureus (strain N315) SA2278 or SAV2490 TR:BAB58652 (EMBL:AP003137) (130 aa) fasta scores: E(): 1e-24, 56.91% id in 123 aa, and to Escherichia coli CTP pyrophosphohydrolase NudG or B1759 SW:NUDG_ECOLI (P77788) (135 aa) fasta scores: E(): 3.3e-13, 41.4% id in 128 aa NP_939380.1 Similar to Mycobacterium tuberculosis cold-shock DEAD-box protein A homolog DeaD or CsdA or Rv1253 or MT1292 or MTCY50.29c SW:DEAD_MYCTU (Q11039) (563 aa) fasta scores: E(): 1.4e-97, 59.85% id in 563 aa, and to Escherichia coli cold-shock DEAD-box protein A DeaD or CsdA or MssB or B3162 SW:DEAD_ECOLI (P23304) (628 aa) fasta scores: E(): 7e-97, 50.32% id in 622 aa NP_939381.1 no database matches NP_939382.1 Similar to Streptomyces coelicolor integral membrane protein scf42.06C TR:Q9L2K7 (EMBL:AL137165) (164 aa) fasta scores: E(): 0.0052, 31.54% id in 168 aa, and to Rhizobium meliloti hypothetical transmembrane protein Smc01456 smc01456 TR:CAC46718 (EMBL:AL591789) (144 aa) fasta scores: E(): 0.27, 23.61% id in 144 aa NP_939383.1 Similar to Mycobacterium tuberculosis hypothetical 25.9 kDa protein Rv2972c or MTCY349.15 TR:P95123 (EMBL:Z83018) (237 aa) fasta scores: E(): 1.3e-16, 34.7% id in 170 aa, and to Streptomyces coelicolor secreted protein scp1.323c or scp1.31 TR:Q99QB5 (EMBL:AL590464) (219 aa) fasta scores: E(): 2.2e-13, 35.18% id in 162 aa NP_939384.1 Similar to Corynebacterium glutamicum proline transport system putP TR:O32355 (EMBL:Y09163) (524 aa) fasta scores: E(): 2.3e-143, 69.23% id in 520 aa, and to Escherichia coli sodium/proline symporter putP or B1015 SW:PUTP_ECOLI (P07117) (502 aa) fasta scores: E(): 2.2e-41, 45.69% id in 499 aa NP_939385.1 Similar to Mycobacterium tuberculosis CDC1551 helicase, SNF2/RAD54 family MT2161 TR:AAK46443 (EMBL:AE007065) (954 aa) fasta scores: E(): 7.8e-94, 38.56% id in 1006 aa, and to Synechocystis sp helicase of the SNF2/RAD54 family SLL1366 TR:P74552 (EMBL:D90916) (1039 aa) fasta scores: E(): 1.9e-83, 34.17% id in 986 aa NP_939386.1 Similar to Streptomyces coelicolor hypothetical 59.8 kDa protein orfZ TR:O86854 (EMBL:AJ007731) (566 aa) fasta scores: E(): 1.2e-07, 31.21% id in 189 aa, and to Sulfolobus solfataricus hypothetical protein Sso1656 sso1656 TR:Q97XQ4 (EMBL:AE006779) (217 aa) fasta scores: E(): 1.1e-06, 25.11% id in 211 aa NP_939387.1 Similar to Mycobacterium tuberculosis CDC1551 exonuclease SbcD-related protein MT1314 TR:AAK45575 (EMBL:AE007006) (417 aa) fasta scores: E(): 3e-43, 40.1% id in 384 aa, and to Bacillus subtilis exonuclease SbcD homolog SW:SBCD_BACSU (P23479) (325 aa) fasta scores: E(): 1.6, 27.13% id in 258 aa NP_939388.1 Similar to Mycobacterium leprae hypothetical protein ML1120 TR:Q9CC83 (EMBL:AL583920) (873 aa) fasta scores: E(): 1.9e-14, 28.49% id in 888 aa, and to Mycobacterium tuberculosis hypothetical 93.4 kDa protein Rv1278 or MT1315 or MTCY50.04c SW:YC78_MYCTU (Q11042) (875 aa) fasta scores: E(): 3.3e-13, 29% id in 893 aa. Contains coiled-coil domains, and thus some probably non-specific similarity to e.g. Drosophila melanogaster myosin heavy chain, non-muscle zip SW:MYSN_DROME (Q99323) (2017 aa) fasta scores: E(): 5.7e-07, 23.06% id in 568 aa NP_939389.1 Similar to Streptomyces coelicolor hypothetical 20.0 kDa protein SC1C2.14C TR:O86515 (EMBL:AL031124) (185 aa) fasta scores: E(): 1e-29, 48.04% id in 179 aa, and to Thermoplasma volcanium hypothetical protein Tvg0219791 TR:BAB59353 (EMBL:AP000991) (177 aa) fasta scores: E(): 2.4e-28, 50.93% id in 161 aa NP_939390.1 Similar to Streptomyces coelicolor MarR-family transcriptional repressor SCE22.22 TR:Q9KYU1 (EMBL:AL355832) (163 aa) fasta scores: E(): 3.5e-17, 37.06% id in 143 aa, and to Escherichia coli transcriptional repressor MprA EmrR or B2684 or Z3985 or ECS3546 SW:MPRA_ECOLI (P24201) (176 aa) fasta scores: E(): 0.0011, 24.79% id in 121 aa NP_939391.1 Similar to Streptomyces coelicolor membrane protein 2SCK8.29C TR:Q9AK23 (EMBL:AL589164) (67 aa) fasta scores: E(): 1.6e-05, 37.03% id in 54 aa, and to Thermotoga maritima conserved hypothetical protein TM1156 TR:Q9X0P0 (EMBL:AE001773) (129 aa) fasta scores: E(): 0.00055, 37.5% id in 56 aa NP_939392.1 Similar to Streptomyces coelicolor hypothetical 23.2 kDa protein SCF43A.07 TR:Q9XAA8 (EMBL:AL096837) (215 aa) fasta scores: E(): 3.3e-26, 44.65% id in 215 aa, and to Deinococcus radiodurans conserved hypothetical protein DR1909 TR:Q9RT57 (EMBL:AE002030) (212 aa) fasta scores: E(): 7.8e-17, 37.44% id in 211 aa NP_939393.1 Similar to Streptomyces coelicolor iron-sulfur protein SCF43A.06 TR:Q9XAA9 (EMBL:AL096837) (492 aa) fasta scores: E(): 9.1e-97, 57.35% id in 483 aa, and to Escherichia coli electron transport protein YkgF or B0307 SW:YKGF_ECOLI (P77536) (475 aa) fasta scores: E(): 5.4e-64, 39.41% id in 482 aa NP_939394.1 Similar to C-terminus of e.g. Escherichia coli anaerobic glycerol-3-phosphate dehydrogenase subunit C GlpC or B2243 or Z3501 or ECS3128 SW:GLPC_ECOLI (P13034) (396 aa) fasta scores: E(): 2.8e-11, 27.71% id in 249 aa, and to C-terminus of Escherichia coli glycolate oxidase iron-sulfur subunit GlcF or gox or B2978 SW:GLCF_ECOLI (P52074) (407 aa) fasta scores: E(): 9.8e-10, 23.27% id in 232 aa NP_939395.1 Similar to Escherichia coli L-lactate permease LldP or LctP or B3603 SW:LLDP_ECOLI (P33231) (551 aa) fasta scores: E(): 1e-58, 36.28% id in 554 aa NP_939396.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_939397.1 Similar to Corynebacterium glutamicum diaminopimelate decarboxylase LysA SW:DCDA_CORGL (P09890) (445 aa) fasta scores: E(): 2.8e-119, 70.61% id in 439 aa, and to Bacillus subtilis diaminopimelate decarboxylase LysA or Lys SW:DCDA_BACSU (P23630) (441 aa) fasta scores: E(): 3e-67, 43.76% id in 425 aa NP_939398.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_939399.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_939400.1 activates fatty acids by binding to coenzyme A NP_939401.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_939402.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_939403.1 Similar to Mycobacterium tuberculosis HemK protein homolog HemK or Rv1300 or MT1339 or MTCY373.20 SW:HEMK_MYCTU (Q10602) (304 aa) fasta scores: E(): 2.7e-33, 44.24% id in 278 aa, and to Escherichia coli protein HemK or B1212 SW:HEMK_ECOLI (P37186) (277 aa) fasta scores: E(): 1.2e-16, 29.71% id in 276 aa NP_939404.1 Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv1301 or MT1340 or MTCY373.21 SW:YD01_MYCTU (Q10618) (217 aa) fasta scores: E(): 2.3e-50, 64.92% id in 211 aa, and to Bacillus subtilis hypothetical 37.0 kDa protein in spoIIR-glyC intergenic region YwlC or Ipc-29D SW:YWLC_BACSU (P39153) (346 aa) fasta scores: E(): 1.2e-18, 33.01% id in 206 aa NP_939405.1 Similar to Mycobacterium tuberculosis undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe or Rv1302 or MT1341 or MTCY373.22 SW:RFE_MYCTU (Q10606) (404 aa) fasta scores: E(): 1e-75, 56.91% id in 369 aa, and to Bacillus subtilis phospho-N-acetylmuramoyl-pentapeptide-transferase MraY SW:MRAY_BACSU (Q03521) (324 aa) fasta scores: E(): 3.6e-10, 26.53% id in 343 aa NP_939406.1 no database matches NP_939407.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_939408.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 NP_939409.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_939410.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_939411.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_939412.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_939413.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_939414.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_939415.1 Similar to Mycobacterium leprae hypothetical 16.5 kDa protein ML1147 or u471B SW:YD12_MYCLE (P53432) (147 aa) fasta scores: E(): 4.8e-12, 31.65% id in 139 aa, and to Mycobacterium tuberculosis hypothetical 16.6 kDa protein Rv1312 MT1352 or MTCY373.32 SW:YD12_MYCTU (Q10620) (147 aa) fasta scores: E(): 1.6e-11, 32.37% id in 139 aa, and to Streptomyces coelicolor secreted/membrane protein 2sc6g5.19 TR:Q9K4D3 (EMBL:AL359152) (151 aa) fasta scores: E(): 1.1e-05, 27.97% id in 143 aa NP_939416.1 Similar to Mycobacterium tuberculosis hypothetical 25.1 kDa protein Rv1321 MT1363 or MTCY130.06 SW:YD21_MYCTU (Q10634) (226 aa) fasta scores: E(): 1.8e-66, 73.79% id in 229 aa, and to Mycobacterium leprae hypothetical 24.4 kDa protein MLl1155 or B1549_c3_223 SW:YD21_MYCLE (P53524) (220 aa) fasta scores: E(): 9.1e-64, 72.56% id in 226 aa NP_939417.1 Similar to Streptomyces coelicolor ATP/GTP-binding protein, doubtful CDS 2SC6G5.35 TR:Q9K4C0 (EMBL:AL359152) (110 aa) fasta scores: E(): 1.1e-12, 46.87% id in 96 aa, and to Mycobacterium tuberculosis hypothetical 11.3 kDa protein Rv1322 MT1363.1 or MTCY130.07 SW:YD22_MYCTU (Q10635) (98 aa) fasta scores: E(): 1.4e-10, 42.22% id in 90 aa NP_939418.1 Similar to Mycobacterium leprae B1549_F2_87 ML1157 TR:Q49717 (EMBL:U00014) (155 aa) fasta scores: E(): 1.2e-28, 55.47% id in 137 aa, and to Mycobacterium tuberculosis CDC1551 4-hydroxyphenylpyruvate dioxygenase C terminal domain containing protein MT1364 TR:AAK45627 (EMBL:AE007009) (152 aa) fasta scores: E(): 3e-27, 53.28% id in 137 aa, and to Pyrococcus horikoshii methylmalonyl-CoA epimerase PHO272 TR:AAK52053 (EMBL:AF364548) (136 aa) fasta scores: E(): 9.8e-13, 38.63% id in 132 aa, and to Homo sapiens methylmalonyl-CoA epimerase TR:AAK52052 (EMBL:AF364547) (176 aa) fasta scores: E(): 2.7e-11, 36.84% id in 133 aa NP_939419.1 Similar to Mycobacterium tuberculosis hypothetical 11.0 kDa protein Rv1898 or MT1949 or MTCY180.20c SW:YI98_MYCTU (O07734) (102 aa) fasta scores: E(): 5.8e-16, 56.43% id in 101 aa, and to Aquifex aeolicus hypothetical 17.9 kDa protein AQ_2067 TR:O67847 (EMBL:AE000771) (157 aa) fasta scores: E(): 4.7e-08, 40.19% id in 102 aa NP_939420.1 Similar to Streptomyces coelicolor iron-siderophore uptake system ATP-binding component SCI51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 1.9e-42, 50.58% id in 255 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein fepC b0588 SW:FEPC_ECOLI (P23878) (271 aa) fasta scores: E(): 1.1e-41, 49.61% id in 262 aa NP_939421.1 Similar to Streptomyces coelicolor iron-siderophore uptake system transmembrane component sci51.26C TR:Q9S214 (EMBL:AL109848) (375 aa) fasta scores: E(): 5e-40, 40.74% id in 324 aa, and to Escherichia coli ferric enterobactin transport system permease fepg fepg or B0589 SW:FEPG_ECOLI (P23877) (330 aa) fasta scores: E(): 1.8e-45, 44.09% id in 322 aa NP_939422.1 Similar to Streptomyces coelicolor iron-siderophore uptake system transmembrane component sci51.27C TR:Q9S213 (EMBL:AL109848) (348 aa) fasta scores: E(): 8e-36, 36.53% id in 323 aa, and to Escherichia coli ferric enterobactin transport system permease fepD or B0590 SW:FEPD_ECOLI (P23876) (334 aa) fasta scores: E(): 5.2e-40, 40.37% id in 322 aa NP_939423.1 Similar to Escherichia coli iron(III) dicitrate-binding periplasmic protein precursor FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.1e-12, 25.55% id in 270 aa, and to Campylobacter jejuni enterochelin uptake periplasmic binding protein CeuE or CJ1355 TR:Q9PMU4 (EMBL:AL139078) (330 aa) fasta scores: E(): 3e-12, 28.35% id in 328 aa, and to Vibrio anguillarum ferric anguibactin-binding protein precursor FatB SW:FATB_VIBAN (P11460) (322 aa) fasta scores: E(): 1.5e-09, 28.72% id in 289 aa NP_939424.1 Weakly similar to Streptomyces coelicolor membrane protein SCL2.30c TR:Q9L269 (EMBL:AL137778) (150 aa) fasta scores: E(): 0.12, 28.3% id in 106 aa NP_939425.1 Similar to Mycobacterium leprae TrxA SWALL:Q49716 (EMBL:U00014) (255 aa) fasta scores: E(): 7.3e-18, 37.22% id in 223 aa, and to Streptomyces coelicolor thioredoxin SC8F4.23 TR:Q9L2A3 (EMBL:AL137242) (318 aa) fasta scores: E(): 6.6e-10, 34.06% id in 320 aa, and to Corynebacterium nephridii thioredoxin C-1 SW:THI1_CORNE (P00275) (105 aa) fasta scores: E(): 0.11, 25.96% id in 104 aa NP_939426.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_939427.1 Similar to Mycobacterium smegmatis glucanase GlgE TR:Q9RP48 (EMBL:AF172946) (697 aa) fasta scores: E(): 2.1e-155, 58.52% id in 692 aa, and to Streptomyces coelicolor alpha-amylase Pep1A TR:Q9L1K2 (EMBL:AL138978) (675 aa) fasta scores: E(): 5.1e-126, 50% id in 662 aa, and to Dictyoglomus thermophilum alpha-amylase 3 AmyC SW:AMY3_DICTH (P14899) (498 aa) fasta scores: E(): 0.17, 23.84% id in 453 aa NP_939428.1 Similar to Mycobacterium tuberculosis ABC transporter ATP-binding protein Rv3041c or MTV012.56c TR:O53288 (EMBL:AL021287) (287 aa) fasta scores: E(): 3.2e-63, 62.95% id in 278 aa, and to Streptomyces coelicolor ABC transporter ATP-binding subunit SCI5.06c TR:Q9X9Z4 (EMBL:AL079332) (265 aa) fasta scores: E(): 1e-41, 49.41% id in 257 aa NP_939429.1 Similar to Mycobacterium tuberculosis hypothetical 31.5 kDa protein Rv3040c or MTV012.55c TR:O53287 (EMBL:AL021287) (288 aa) fasta scores: E(): 4.1e-25, 37.2% id in 258 aa, and to uncultured proteobacterium EBAC31A08 predicted MutT superfamily hydrolase TR:Q9F7R7 (EMBL:AF279106) (264 aa) fasta scores: E(): 8.4e-18, 31.79% id in 239 aa NP_939430.1 Similar to Mycobacterium tuberculosis hypothetical 39.1 kDa protein Rv3037c or MTV012.52C TR:O53284 (EMBL:AL021287) (358 aa) fasta scores: E(): 3.1e-43, 42.49% id in 353 aa, and to Streptomyces coelicolor Sc6g4.36C protein sc6g4.36C TR:O86799 (EMBL:AL031317) (426 aa) fasta scores: E(): 2.5e-18, 31.36% id in 322 aa NP_939431.1 Similar to Mycobacterium tuberculosis electron transfer flavoprotein beta-subunit FixA or Rv3029c or MT3113 or MTV012.44c SW:ETFB_MYCTU (O53276) (266 aa) fasta scores: E(): 8.4e-45, 51.31% id in 267 aa NP_939432.1 Similar to Mycobacterium tuberculosis electron transfer flavoprotein alpha-subunit EtfA or FixB or Rv3028c or MT3112 or MTV012.43c SW:ETFA_MYCTU (O53275) (318 aa) fasta scores: E(): 1.8e-48, 51.1% id in 317 aa NP_939433.1 Similar to Mycobacterium tuberculosis CDC1551 aminotransferase, class V MT3109 TR:AAK47439 (EMBL:AE007129) (393 aa) fasta scores: E(): 1.1e-52, 45.71% id in 385 aa, and to Mycobacterium tuberculosis NifS-like protein Rv3025c or MTV012.40C TR:O53272 (EMBL:AL021287) (393 aa) fasta scores: E(): 1.1e-52, 45.71% id in 385 aa, and to Ruminococcus flavefaciens cysteine desulfurase IscS or NifS SW:ISCS_RUMFL (O54055) (396 aa) fasta scores: E(): 2.1e-40, 36.48% id in 381 aa NP_939434.1 Similar to Streptomyces coelicolor hypothetical 30.6 kDa protein 2scc13.11C TR:Q9F3H8 (EMBL:AL442165) (289 aa) fasta scores: E(): 5.6e-28, 36.2% id in 279 aa, and to Neisseria meningitidis (serogroup A), and transferase nma1087 or nmb0869 TR:Q9JQL8 (EMBL:AL162755) (263 aa) fasta scores: E(): 1.6e-09, 26.42% id in 246 aa, and to Escherichia coli spermidine synthase spee or B0121 SW:SPEE_ECOLI (P09158) (287 aa) fasta scores: E(): 0.0013, 28.28% id in 152 aa NP_939435.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_939436.1 Similar to Mycobacterium leprae hypothetical protein ML1706 TR:Q9CBR6 (EMBL:AL583923) (337 aa) fasta scores: E(): 4.5e-19, 32.26% id in 313 aa, and to Mycobacterium tuberculosis CDC1551 vitamin-b12 independent methionine synthase MT3095 TR:AAK47424 (EMBL:AE007129) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa, and to Mycobacterium tuberculosis hypothetical 34.2 kDa protein Rv3015c or MTV012.29C TR:O53262 (EMBL:AL021287) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa NP_939437.1 3'-5' exonuclease of DNA polymerase III NP_939438.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_939439.1 Similar to Mycobacterium tuberculosis hypothetical 23.0 kDa protein Rv3013 or MTV012.27 TR:O53260 (EMBL:AL021287) (218 aa) fasta scores: E(): 2.6e-27, 40.63% id in 219 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3093 TR:AAK47422 (EMBL:AE007128) (240 aa) fasta scores: E(): 2.8e-27, 40.63% id in 219 aa, and to Mycobacterium leprae hypothetical 24.4 kDa protein MLCB637.11c TR:O33103 (EMBL:Z99263) (230 aa) fasta scores: E(): 1.3e-26, 40.18% id in 219 aa, and to Mycobacterium leprae hypothetical protein ML1704 TR:Q9CBR7 (EMBL:AL583923) (232 aa) fasta scores: E(): 1.3e-26, 40.18% id in 219 aa NP_939440.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_939441.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_939442.1 Similar to Bacillus halodurans ribosomal-protein (S18)-alanine acetyltransferase BH0547 TR:Q9KFD4 (EMBL:AP001508) (151 aa) fasta scores: E(): 0.0026, 52.83% id in 53 aa, and to Homo sapiens similar to spermidine/spermine N1-acetyl transferase TR:AAH11751 (EMBL:BC011751) (170 aa) fasta scores: E(): 0.0061, 28.85% id in 149 aa NP_939443.1 Similar to Mycobacterium tuberculosis CDC1551 drug transporter MT1289 TR:AAK45547 (EMBL:AE007004) (579 aa) fasta scores: E(): 9.3e-70, 43.87% id in 449 aa, and to Streptomyces coelicolor transmembrane efflux protein SCD82.12 TR:Q9L0L9 (EMBL:AL160431) (490 aa) fasta scores: E(): 5.7e-43, 31.79% id in 456 aa, and to Streptomyces glaucescens tetracenomycin C resistance and export protein TcmA SW:TCMA_STRGA (P39886) (538 aa) fasta scores: E(): 3.5e-39, 31.29% id in 425 aa NP_939444.1 Similar to Streptomyces coelicolor membrane protein SCE6.24 TR:Q9KZR4 (EMBL:AL353832) (100 aa) fasta scores: E(): 4.1e-13, 49.47% id in 95 aa NP_939445.1 Similar to Streptomyces coelicolor FecCD-family membrane transport protein SC2H12.15 TR:Q9K469 (EMBL:AL359215) (368 aa) fasta scores: E(): 2.3e-50, 48.1% id in 343 aa, and to Yersinia pestis hemin transport system permease HmuU YPO0280 SW:HMUU_YERPE (Q56992) (334 aa) fasta scores: E(): 6.8e-30, 36.33% id in 344 aa NP_939446.1 Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 5.1e-24, 35.15% id in 256 aa, and to Escherichia coli iron(III)dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5.5e-24, 37.86% id in 243 aa NP_939447.1 Similar to Streptomyces coelicolor iron transport lipoprotein SC2H12.17 TR:Q9K467 (EMBL:AL359215) (345 aa) fasta scores: E(): 8.3e-30, 36.76% id in 321 aa, and to Yersinia pestis hemin-binding periplasmic protein HmuT precursor YPO0281 SW:HMUT_YERPE (Q56991) (279 aa) fasta scores: E(): 0.022, 22.69% id in 282 aa NP_939449.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_939450.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_939451.1 Similar to Escherichia coli ORF_O346 B3001 TR:Q46851 (EMBL:U28377) (346 aa) fasta scores: E(): 2.5e-73, 56.21% id in 354 aa, to Streptomyces coelicolor oxidoreductase SC7H9.06 TR:Q9EWJ0 (EMBL:AL450223) (348 aa) fasta scores: E(): 1.6e-65, 58.48% id in 342 aa, and to Homo sapiens voltage-gated potassium channel beta-2 subunit KcnAB2 or KcnA2B or KcnK2 TR:Q13303 (EMBL:U33429) (367 aa) fasta scores: E(): 9.5e-27, 34.74% id in 331 aa NP_939452.1 Similar to Corynebacterium glutamicum lysine exporter protein LysE SW:LYSE_CORGL (P94633) (233 aa) fasta scores: E(): 3.8e-40, 45.02% id in 231 aa, and to Escherichia coli hypothetical protein YggA or B2923 SW:YGGA_ECOLI (P11667) (211 aa) fasta scores: E(): 3.1e-09, 32.44% id in 225 aa NP_939453.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport NP_939454.1 Similar to Streptomyces lividans and S. coelicolor hypothetical 38.1 kDa protein 3SCF60.09 TR:O85700 (EMBL:AF072709) (341 aa) fasta scores: E(): 4.8e-70, 54.38% id in 331 aa, and to Rhodobacter sphaeroides hypothetical 38.5 kDa protein ORF11 TR:O33560 (EMBL:AJ000977) (333 aa) fasta scores: E(): 5.6e-48, 45.28% id in 318 aa NP_939455.1 Similar to Mycobacterium tuberculosis hypothetical 25.9 kDa protein Rv2972c or MTCY349.15 TR:P95123 (EMBL:Z83018) (237 aa) fasta scores: E(): 3.4e-25, 36.55% id in 238 aa, and to Streptomyces coelicolor lipoprotein SCE41.16c TR:Q9F2P3 (EMBL:AL442120) (258 aa) fasta scores: E(): 1.5e-19, 37.86% id in 169 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRSFIRK) at the N-terminal region NP_939456.1 Similar to Mycobacterium leprae hypothetical 29.5 kDa protein ML1698 or MLCB637.18 TR:O33110 (EMBL:Z99263) (277 aa) fasta scores: E(): 6.4e-10, 30.79% id in 276 aa, and to Mycobacterium tuberculosis hypothetical 28.9 kDa protein Rv3005c or MTV012.19c TR:O53252 (EMBL:AL021287) (279 aa) fasta scores: E(): 1.3e-08, 28.15% id in 277 aa NP_939457.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_939458.1 Similar to Mycobacterium tuberculosis low molecular weight protein antigen 6 Cfp6 or Rv3004 or MT3084.1 or MTV012.18 SW:CFP6_MYCTU (O53251) (112 aa) fasta scores: E(): 7.9e-07, 34.57% id in 107 aa NP_939459.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate NP_939460.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_939461.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_939462.1 Similar to Staphylococcus aureus (strain N315) CzrB protein or SA1948 or SAV2146 TR:BAB58308 (EMBL:AP003136) (325 aa) fasta scores: E(): 4e-37, 37.74% id in 302 aa, and to Alcaligenes eutrophus cobalt-zinc-cadmium resistance protein CzcD SW:CZCD_ALCEU (P13512) (316 aa) fasta scores: E(): 9.2e-36, 40.84% id in 284 aa NP_939463.1 Similar to Anabaena sp All3615 protein TR:BAB75314 (EMBL:AP003593) (621 aa) fasta scores: E(): 1.8e-37, 29.29% id in 594 aa, and to Streptomyces coelicolor hypothetical 67.8 kDa protein SC4G2.12c TR:O86684 (EMBL:AL031371) (605 aa) fasta scores: E(): 9.5e-29, 34.55% id in 602 aa NP_939465.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate NP_939466.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_939467.1 Some similarity to Vibrio cholerae DNA polymerase III, epsilon subunit, VC1290 TR:Q9KSG6 (EMBL:AE004208) (236 aa) fasta scores: E(): 0.37, 38.33% id in 60 aa NP_939468.1 no significant database matches NP_939469.1 Similar to Mycobacterium tuberculosis possible 2-hydroxyhepta-2,4-diene- 1,7-dioate isomerase Rv2993c or MTV012.07c TR:O53242 (EMBL:AL021287) (239 aa) fasta scores: E(): 2.5e-42, 48.73% id in 238 aa NP_939470.1 Similar to Streptomyces coelicolor methyltransferase SCF43A.25c TR:Q9XA90 (EMBL:AL096837) (215 aa) fasta scores: E(): 2.2e-12, 36.23% id in 207 aa NP_939471.1 synthesizes isochorismate acid from chorismate NP_939472.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_939473.1 Similar to Mycobacterium tuberculosis CDC1551 esterase, MT3397 TR:AAK47740 (EMBL:AE007148) (304 aa) fasta scores: E(): 5.3e-09, 30.57% id in 242 aa, and to Piromyces equi cinnamoyl ester hydrolase EstA TR:Q9Y871 (EMBL:AF164516) (536 aa) fasta scores: E(): 1.2e-06, 25.19% id in 258 aa, and to Pseudomonas fluorescens esterase D XynD TR:Q51815 (EMBL:X58956) (583 aa) fasta scores: E(): 5.8e-06, 27.37% id in 274 aa NP_939474.1 Similar to Streptomyces coelicolor SC10A5.11 protein TR:O54102 (EMBL:AL021529) (198 aa) fasta scores: E(): 8.8e-14, 32.94% id in 170 aa, and to Streptomyces roseosporus WhiR protein TR:P72569 (EMBL:U58281) (179 aa) fasta scores: E(): 1.5e-05, 24.5% id in 151 aa NP_939475.1 Similar to Streptomyces coelicolor membrane protein SC10A5.10c SW:MMLB_STRCO (O54101) (847 aa) fasta scores: E(): 5.3e-106, 47.61% id in 733 aa, and to Mycobacterium tuberculosis membrane protein MmpL8 or Rv3823c or MT3931 or MTCY409.07 SW:MML8_MYCTU (O07800) (1089 aa) fasta scores: E(): 1.1e-21, 27.76% id in 461 aa NP_939476.1 Similar to Mycobacterium leprae hypothetical protein ML0099 TR:Q9CDB3 (EMBL:AL583917) (336 aa) fasta scores: E(): 7e-07, 27.58% id in 261 aa, and to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 4.2e-06, 27.98% id in 243 aa NP_939478.1 Doubtful CDS. No significant database matches NP_939479.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate NP_939480.1 Similar to Streptomyces verticillus PhnA-like protein TR:Q9FB32 (EMBL:AF210249) (117 aa) fasta scores: E(): 3.3e-20, 56.19% id in 121 aa, and to Escherichia coli PhnA protein or B4108 or Z5710 or ECS5090 SW:PHNA_ECOLI (P16680) (111 aa) fasta scores: E(): 7.1e-17, 51.28% id in 117 aa NP_939481.1 Similar to Bacillus subtilis biotin synthase BioB SW:BIOB_BACSU (P53557) (335 aa) fasta scores: E(): 1.4e-38, 38.19% id in 322 aa, and to Corynebacterium glutamicum biotin synthase BioB SW:BIOB_CORGL (P46396) (334 aa) fasta scores: E(): 3.1e-31, 35.78% id in 299 aa NP_939482.1 Similar to Synechocystis sp. hypothetical 21.9 kDa protein SLL1660 SWALL:P72810 (EMBL:D90901) (194 aa) fasta scores: E(): 2.9e-16, 33.13% id in 166 aa, and to Pseudomonas denitrificans hypothetical 19.2 kDa protein in cobO 3'region SWALL:YCB8_PSEDE (SWALL:P29941) (175 aa) fasta scores: E(): 6.6e-07, 34.24% id in 146 aa NP_939483.1 Similar to Mycobacterium tuberculosis probable transcriptional regulator Rv2989 or MT3067 or MTV012.03 SWALL:AAK47396 (EMBL:AL021287) (267 aa) fasta scores: E(): 8.6e-39, 48.26% id in 230 aa, and to Streptomyces coelicolor transcriptional regulator SC1C2.33c SWALL:O86533 (EMBL:AL031124) (238 aa) fasta scores: E(): 7.2e-31, 42.24% id in 232 aa NP_939484.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate NP_939485.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D NP_939486.1 Similar to Mycobacterium leprae hypothetical protein ML1682 SWALL:Q9CBR8 (EMBL:AL583923) (311 aa) fasta scores: E(): 1.4e-40, 42.66% id in 300 aa, and N-terminal region to Streptomyces coelicolor MutT-like protein SCD84.10c SWALL:Q9KZV8 (EMBL:AL353816) (142 aa) fasta scores: E(): 4.4e-13, 42.4% id in 125 aa NP_939487.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_939488.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_939489.1 Similar to Mycobacterium leprae possible secreted protein ML1677 TR:Q9CBS1 (EMBL:AL583923) (191 aa) fasta scores: E(): 8.9e-13, 32.447% id in 188 aa, and to Mycobacterium tuberculosis hypothetical 18.8 kDa protein Rv2980 or MTCY349.07c TR:P95115 (EMBL:Z83018) (181 aa) fasta scores: E(): 1.5e-09, 31.098% id in 164 aa NP_939490.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP NP_939491.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_939492.1 Similar to Mycobacterium tuberculosis hypothetical 46.7 kDa protein Rv2974c or MTCY349.13 TR:P95121 (EMBL:Z83018) (470 aa) fasta scores: E(): 4e-28, 33.402% id in 485 aa, and to Clostridium acetobutylicum predicted kinase related to hydroxyacetone kinase YloV ortholog CAC1735 TR:AAK79701 (EMBL:AE007682) (547 aa) fasta scores: E(): 3.8e-21, 25.690% id in 471 aa NP_939493.1 Similar to Bacillus subtilis ATP-dependent DNA helicase RecG SW:RECG_BACSU (O34942) (682 aa) fasta scores: E(): 3.3e-69, 33.862% id in 694 aa, and to Escherichia coli ATP-dependent DNA helicase RecG or B3652 SW:RECG_ECOLI (P24230) (693 aa) fasta scores: E(): 8.9e-63, 34.765% id in 722 aa NP_939494.1 Similar to C-terminus of Mycobacterium smegmatis pyruvate carboxylase Pyc TR:Q9F843 (EMBL:AF262949) (1127 aa) fasta scores: E(): 1.9e-05, 47.761% id in 67 aa, to Bacillus subtilis YngXX TR:Q9R9I3 (EMBL:AF184956) (73 aa) fasta scores: E(): 0.0043, 36.765% id in 68 aa, and to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl- transferase SW:BCCP_PROFR (P02904) (123 aa) fasta scores: E(): 0.0079, 38.806% id in 67 aa NP_939495.1 Similar to Mycobacterium tuberculosis hypothetical 19.8 kDa protein Rv2966c or MTCY349.21 TR:P95128 (EMBL:Z83018) (188 aa) fasta scores: E(): 2.6e-22, 42.703% id in 185 aa, and to Streptomyces coelicolor methylase SC7A1.11 TR:Q9ZBR2 (EMBL:AL034447) (195 aa) fasta scores: E(): 1.2e-21, 44.505% id in 182 aa NP_939496.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_939499.1 Similar to Streptomyces coelicolor ATP-binding protein AtrC SWALL:Q9F3K7 (EMBL:AL391763) (253 aa) fasta scores: E(): 5.1e-58, 68% id in 250 aa, and to Rhizobium sp TAL1145 MidC SWALL:Q9EYT0 (EMBL:AF312768) (265 aa) fasta scores: E(): 1.9e-52, 60.78% id in 255 aa NP_939500.1 Similar to Streptomyces coelicolor permease AtrB SWALL:Q9F3K6 (EMBL:AL391763) (316 aa) fasta scores: E(): 7.1e-49, 50.72% id in 276 aa, and to Rhizobium meliloti amino acid uptake ABC transporter permease RB0674 or SMB21095 SWALL:CAC49074 (EMBL:AL603644) (290 aa) fasta scores: E(): 3.5e-37, 42.96% id in 263 aa NP_939501.1 Similar to Rhizobium spTAL1145 MidA SWALL:Q9EYT2 (EMBL:AF312768) (281 aa) fasta scores: E(): 4.6e-18, 30.36% id in 247 aa, and to Escherichia coli glutamine-binding periplasmic protein precursor GlnH or B0811 or Z1033 or ECS0889 SWALL:GLNH_ECOLI (SWALL:P10344) (248 aa) fasta scores: E(): 1.1e-13, 30.55% id in 252 aa NP_939502.1 Similar to Vibrio cholerae hypothetical protein VCA0040 SWALL:Q9KNC5 (EMBL:AE004347) (308 aa) fasta scores: E(): 3.4e-22, 31.48% id in 270 aa, and to Methanothermobacter thermautotrophicus hypothetical 35.5 kDa protein MTH465 SWALL:O26565 (EMBL:AE000831) (319 aa) fasta scores: E(): 2.9e-18, 31.12% id in 241 aa NP_939503.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_939504.1 Similar to Streptomyces coelicolor hypothetical 24.3 kDa protein SC7H2.13 SWALL:Q9S2K4 (EMBL:AL109732) (220 aa) fasta scores: E(): 1.4e-39, 50% id in 216 aa, and to Bacillus halodurans BH0355 protein SWALL:Q9KFW5 (EMBL:AP001508) (246 aa) fasta scores: E(): 1.3e-10, 28.51% id in 242 aa NP_939505.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_939506.1 Similar to Pasteurella multocida hypothetical protein PM0933 SWALL:Q9CMA1 (EMBL:AE006132) (462 aa) fasta scores: E(): 9.1e-43, 32.62% id in 469 aa, and to Escherichia coli anaerobic C4-dicarboxylate transporter DcuC or B0621 or Z0766 or ECS0660 SWALL:DCUC_ECOLI (SWALL:Q47134) (461 aa) fasta scores: E(): 9.6e-19, 31.76% id in 466 aa NP_939507.1 Similar to Bacillus subtilis transcription antiterminator LicT or N15A SWALL:LICT_BACSU (SWALL:P39805) (277 aa) fasta scores: E(): 2.6e-20, 28.72% id in 275 aa, and to Escherichia coli cryptic beta-glucoside Bgl operon antiterminator BglG or BglC or B3723 SWALL:BGLG_ECOLI (SWALL:P11989) (278 aa) fasta scores: E(): 1.4e-18, 27.33% id in 278 aa NP_939508.1 Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa NP_939509.1 Similar to Corynebacterium glutamicum dephospho-CoA kinase CoaE SWALL:COAE_CORGL (SWALL:P56187) (195 aa) fasta scores: E(): 7.6e-25, 50.81% id in 185 aa, and to Escherichia coli dephospho-CoA kinase CoaE or B0103 or Z0113 or ECS0107 SWALL:COAE_ECOLI (SWALL:P36679) (206 aa) fasta scores: E(): 2.4e-15, 38.37% id in 185 aa NP_939510.1 Similar to Archaeoglobus fulgidus coenzyme PQQ synthesis protein AF2413 SWALL:O30258 (EMBL:AE001109) (375 aa) fasta scores: E(): 1.1e-54, 40.79% id in 375 aa, and to Methylobacterium extorquens coenzyme PQQ synthesis protein E PqqE SWALL:PQQE_METEX (SWALL:P71517) (384 aa) fasta scores: E(): 1e-05, 24.67% id in 381 aa NP_939511.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_939512.1 Similar to Mycobacterium tuberculosis CDC1551 universal stress protein family MT1672 SWALL:AAK45942 (EMBL:AE007031) (146 aa) fasta scores: E(): 1.4e-19, 49.31% id in 146 aa, and to Rhizobium meliloti hypothetical protein RA0598 or SMA1100 SWALL:AAK65256 (EMBL:AE007249) (153 aa) fasta scores: E(): 6.8e-07, 38.37% id in 86 aa NP_939513.1 Similar to Streptomyces coelicolor helicase SCE59.11c SWALL:Q9L1U3 (EMBL:AL138851) (744 aa) fasta scores: E(): 5.4e-32, 34.77% id in 788 aa, and to Clostridium acetobutylicum superfamily I DNA helicase CAC1026 SWALL:AAK79002 (EMBL:AE007618) (763 aa) fasta scores: E(): 2e-15, 23.98% id in 788 aa NP_939514.1 N-terminal region similar to Streptomyces coelicolor hypothetical 18.8 kDa protein SC9H11.26c SWALL:Q9KYL5 (EMBL:AL356592) (177 aa) fasta scores: E(): 9.8e-11, 35.13% id in 148 aa. Note: Possible colied-coil region at C-terminal domain from residue 242 till the end NP_939515.1 Similar to Mycobacterium tuberculosis CDC1551 metallo-beta-lactamase superfamily protein MT1673 SWALL:AAK45943 (EMBL:AE007031) (264 aa) fasta scores: E(): 5e-29, 45.58% id in 204 aa, and to Streptomyces coelicolor hydrolase SCC54.20 SWALL:Q9Z505 (EMBL:AL035591) (218 aa) fasta scores: E(): 7.2e-26, 40.55% id in 217 aa NP_939516.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_939517.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_939518.1 Similar to Streptomyces coelicolor 50S ribosomal protein L35 RpmI or SCI35.21c SWALL:RL35_STRCO (SWALL:O88059) (64 aa) fasta scores: E(): 1.1e-10, 58.06% id in 62 aa, and to Bacillus subtilis 50S ribosomal protein L35 RpmI SWALL:RL35_BACSU (SWALL:P55874) (65 aa) fasta scores: E(): 1.5e-07, 50% id in 60 aa NP_939519.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_939521.1 Similar to Mycobacterium tuberculosis TsnR or Rv1644 or MT1682 or MTCY06H11.08 SWALL:AAK45951 (EMBL:Z85982) (260 aa) fasta scores: E(): 2.4e-45, 52.85% id in 263 aa, and to Mycobacterium leprae rRNA methyltransferase TsnR or ML1397 SWALL:Q9CC19 (EMBL:AL583921) (259 aa) fasta scores: E(): 6.7e-45, 52.89% id in 259 aa, and to Bacillus halodurans rRNA methylase BH3112 SWALL:Q9K894 (EMBL:AP001517) (251 aa) fasta scores: E(): 3.2e-17, 35.24% id in 244 aa NP_939522.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_939523.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_939524.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_939525.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_939526.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_939527.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine NP_939528.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation NP_939529.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes NP_939530.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_939531.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_939532.1 Similar to Caulobacter crescentus hypothetical protein CC0108 SWALL:Q9ABW2 (EMBL:AE005685) (65 aa) fasta scores: E(): 9.4e-08, 44.64% id in 56 aa, and to Mycobacterium tuberculosis hypothetical 8.3 kDa protein Rv1684 or MTCI125.06 SWALL:O33186 (EMBL:Z98268) (74 aa) fasta scores: E(): 2.1e-07, 57.69% id in 52 aa. Note: Two possible alternative start codons at residues 8 or 11 NP_939533.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_939534.1 C-terminal region similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1730 SWALL:AAK45999 (EMBL:AE007035) (250 aa) fasta scores: E(): 4e-32, 47.73% id in 243 aa, and to Streptomyces coelicolor hypothetical 22.8 kDa protein SCI51.30c SWALL:Q9S210 (EMBL:AL109848) (210 aa) fasta scores: E(): 3.1e-24, 49.17% id in 181 aa NP_939535.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1731 SWALL:AAK46000 (EMBL:AE007035) (353 aa) fasta scores: E(): 1e-33, 41.06% id in 302 aa, and to Streptomyces coelicolor hypothetical 35.2 kDa protein SCI51.28c SWALL:Q9S212 (EMBL:AL109848) (343 aa) fasta scores: E(): 4e-32, 39.4% id in 302 aa NP_939536.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939537.1 Similar to Mycobacterium tuberculosis CDC1551 cytotoxin/hemolysin MT1733 SWALL:AAK46002 (EMBL:AE007035) (268 aa) fasta scores: E(): 2.2e-53, 56.56% id in 274 aa, and to Caulobacter crescentus hemolysin A CC1324 SWALL:Q9A8M9 (EMBL:AE005808) (243 aa) fasta scores: E(): 1.2e-29, 42.27% id in 246 aa NP_939538.1 catalyzes the phosphorylation of NAD to NADP NP_939539.1 Similar to Mycobacterium tuberculosis DNA repair protein RecN or Rv1696 or MT1735 or MTCI125.18 SWALL:RECN_MYCTU (SWALL:O33197) (587 aa) fasta scores: E(): 1.9e-53, 47.99% id in 598 aa, and to Streptomyces coelicolor DNA repair protein RecN or SCI51.20c SWALL:RECN_STRCO (SWALL:Q9S220) (572 aa) fasta scores: E(): 1.2e-54, 45.64% id in 585 aa, and to Bacillus subtilis DNA repair protein RecN SWALL:RECN_BACSU (SWALL:P17894) (576 aa) fasta scores: E(): 2.5e-38, 32.31% id in 591 aa NP_939540.1 Similar to Mycobacterium leprae conserved membrane protein ML1361 SWALL:Q9CC30 (EMBL:AL583921) (393 aa) fasta scores: E(): 7.2e-57, 44.16% id in 394 aa, and to Mycobacterium tuberculosis hypothetical 42.4 kDa protein Rv1697 or MTCI125.19 SWALL:O33198 (EMBL:Z98268) (393 aa) fasta scores: E(): 2.9e-56, 43.4% id in 394 aa NP_939541.1 Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1698 precursor or MT1737 or MTCI125.20 SWALL:YG98_MYCTU (SWALL:P58212) (314 aa) fasta scores: E(): 4.4e-22, 31.57% id in 304 aa NP_939542.1 Similar to Mycobacterium tuberculosis CDC1551 MutT/NudXx family protein MT1739 SWALL:AAK46008 (EMBL:AE007036) (207 aa) fasta scores: E(): 6.7e-35, 48.3% id in 207 aa, and to Bacillus subtilis ADP-ribose pyrophosphatase NudF SWALL:ADPP_BACSU (SWALL:P54570) (185 aa) fasta scores: E(): 7.9e-15, 35.06% id in 154 aa NP_939543.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_939544.1 Similar to Mycobacterium leprae possible regulatory protein ML1367 SWALL:Q9CC29 (EMBL:AL583921) (287 aa) fasta scores: E(): 1.8e-76, 72.72% id in 275 aa, and to Bacillus subtilis sporulation initiation inhibitor protein Soj SWALL:SOJ_BACSU (SWALL:P37522) (253 aa) fasta scores: E(): 1.2e-44, 51.21% id in 248 aa NP_939545.1 Similar to Mycobacterium tuberculosis hypothetical 30.6 kDa protein Rv1709 or MTCI125.31 SWALL:O33208 (EMBL:Z98268) (278 aa) fasta scores: E(): 2.2e-55, 60.31% id in 252 aa, and to Streptomyces coelicolor hypothetical 29.6 kDa protein SCI51.10c SWALL:Q9S230 (EMBL:AL109848) (264 aa) fasta scores: E(): 1.2e-46, 59.41% id in 239 aa NP_939546.1 Similar to Corynebacterium glutamicum dethiobiotin synthetase BioD SWALL:BIOD_CORGL (SWALL:P46397) (224 aa) fasta scores: E(): 4e-08, 38.94% id in 208 aa, and to Streptomyces coelicolor dethiobiotin synthetase BioD SWALL:Q9FCC1 (EMBL:AL391014) (238 aa) fasta scores: E(): 3.6e-06, 28.37% id in 222 aa. Note: Similar to the downstream CDS DIP1192, 222 aa; E(): 1.3e-13; 38.914% identity in 221 aa overlap - possible duplication NP_939547.1 Similar to Bacillus subtilis hypothetical transporter YclF SWALL:YCLF_BACSU (SWALL:P94408) (492 aa) fasta scores: E(): 2e-53, 33.73% id in 495 aa, and to Neisseria meningitidis peptide transporter NMA0222 SWALL:Q9JWV5 (EMBL:AL162752) (485 aa) fasta scores: E(): 6.2e-47, 34.63% id in 488 aa NP_939548.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate NP_939549.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_939550.1 Similar to Streptomyces coelicolor Na+/H+ antiporter SC4A10.04c SWALL:Q9S2Y0 (EMBL:AL109663) (528 aa) fasta scores: E(): 1.2e-47, 39.09% id in 532 aa, and to Rhizobium loti Na+/H+ antiporter MLL3064 SWALL:Q98H22 (EMBL:AP003001) (517 aa) fasta scores: E(): 9.6e-31, 28.62% id in 531 aa NP_939551.1 Similar to Mycobacterium leprae hypothetical 25.3 kDa protein ML1369 or MLC1351.04C SWALL:O05669 (EMBL:Z95117) (231 aa) fasta scores: E(): 3.1e-33, 59.19% id in 174 aa, and to Bacillus halodurans BH1561 protein SWALL:Q9KCL0 (EMBL:AP001512) (197 aa) fasta scores: E(): 1.7e-13, 38.67% id in 181 aa NP_939552.1 Similar to Mycobacterium tuberculosis hypothetical 27.6 kDa protein Rv1711 or MT1751.1 or MTCI125.33 SWALL:YH11_MYCTU (SWALL:O33210) (254 aa) fasta scores: E(): 2.8e-52, 60.74% id in 242 aa, and to Bacillus subtilis ribosomal large subunit pseudouridine synthase B RluB SWALL:RLUB_BACSU (SWALL:P35159) (229 aa) fasta scores: E(): 2e-28, 46.72% id in 229 aa. Note: Alternative start codon at residue 55 NP_939553.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_939554.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_939555.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters NP_939556.1 Similar to, although longer in its N-terminal region than Mycobacterium tuberculosis methyltransferase Rv3342 or MT3445 or MTV016.42 SWALL:YX42_MYCTU (SWALL:O53392) (243 aa) fasta scores: E(): 2e-16, 31.71% id in 227 aa, and to Pseudomonas aeruginosa hypothetical protein PA0558 SWALL:Q9I5X8 (EMBL:AE004492) (255 aa) fasta scores: E(): 8.9e-11, 28.06% id in 253 aa NP_939557.1 Similar to Corynebacterium glutamicum hypothetical 45.7 kDa protein in lysI 3'region SWALL:YLI2_CORGL (SWALL:P35866) (426 aa) fasta scores: E(): 4.7e-68, 46.93% id in 424 aa, and to Mycobacterium tuberculosis hypothetical 51.8 kDa protein Rv1639c or MTCY06H11.03c SWALL:P94973 (EMBL:Z85982) (489 aa) fasta scores: E(): 1.8e-16, 23.89% id in 385 aa NP_939558.1 Similar to Streptomyces coelicolor conserved hypothetical protein SCI52.19 SWALL:Q9AD90 (EMBL:AL590507) (124 aa) fasta scores: E(): 2.7e-20, 49.58% id in 121 aa, and to Escherichia coli hypothetical protein YchJ or B1233 SWALL:YCHJ_ECOLI (SWALL:P37052) (152 aa) fasta scores: E(): 7.6e-15, 38.71% id in 124 aa NP_939559.1 Similar to Rhizobium meliloti hypothetical protein RA1044 or SMA1898 SWALL:AAK65702 (EMBL:AE007290) (408 aa) fasta scores: E(): 8.8e-49, 39.34% id in 399 aa, and to Clostridium acetobutylicum alpha/beta superfamily hydrolase CAC3665 SWALL:AAK81587 (EMBL:AE007861) (265 aa) fasta scores: E(): 2.6e-07, 22.43% id in 263 aa NP_939560.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins NP_939561.1 Similar to Mycobacterium smegmatis signal transduction protein GarA SWALL:Q9RP36 (EMBL:AF173844) (158 aa) fasta scores: E(): 6.6e-34, 68.21% id in 151 aa, and to Mycobacterium tuberculosis hypothetical 17.3 kDa protein Rv1827 or MT1875 or MTCY1A11.16c SWALL:YI27_MYCTU (SWALL:Q50606) (162 aa) fasta scores: E(): 3.7e-32, 67.83% id in 143 aa NP_939562.1 Similar to Streptomyces coelicolor hypothetical 26.5 kDa protein SC1A8A.03c SWALL:Q9KZP9 (EMBL:AL353861) (246 aa) fasta scores: E(): 1.4e-27, 41.44% id in 222 aa, and to Mycobacterium tuberculosis hypothetical 26.4 kDa protein Rv1828 or MT1876 or MTCY1A11.15c SWALL:YI28_MYCTU (SWALL:Q50605) (247 aa) fasta scores: E(): 1.2e-14, 40.25% id in 236 aa NP_939563.1 Similar to Mycobacterium leprae hypothetical 18.1 kDa protein ML2074 or MLCB1788.34c SWALL:O32917 (EMBL:AL008609) (164 aa) fasta scores: E(): 7.8e-13, 32.02% id in 153 aa, and to Mycobacterium tuberculosis hypothetical 18.1 kDa protein Rv1829 or MT1877 or MTCY1A11.14c SWALL:YI29_MYCTU (SWALL:Q50604) (164 aa) fasta scores: E(): 9.1e-13, 34.07% id in 135 aa NP_939564.1 Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa NP_939566.1 Similar to Rhodococcus fascians hypothetical 34.0 kDa protein SWALL:Q9AE56 (EMBL:AJ301559) (304 aa) fasta scores: E(): 2.2e-46, 44.91% id in 285 aa NP_939567.1 Similar to Rhodococcus fascians hypothetical 40.3 kDa protein SWALL:Q9AE57 (EMBL:AJ301559) (380 aa) fasta scores: E(): 5.4e-62, 50.28% id in 348 aa, to Streptomyces coelicolor integral membrane protein SC6D7.04 SWALL:Q9RKZ3 (EMBL:AL133213) (347 aa) fasta scores: E(): 8.2e-47, 40.93% id in 342 aa, and to Bacillus subtilis hypothetical 49.9 kDa protein in citA-sspB intergenic region YhdP SWALL:YHDP_BACSU (SWALL:O07585) (444 aa) fasta scores: E(): 5.3e-34, 34.48% id in 348 aa NP_939568.1 Similar to Mycobacterium tuberculosis hypothetical 48.1 kDa protein Rv1842c or MT1890 or MTCY1A11.02 or MTCY359.31 SWALL:YI42_MYCTU (SWALL:Q50592) (455 aa) fasta scores: E(): 8.3e-77, 49.55% id in 444 aa, and to Myxococcus xanthus hemolysin TlyC SWALL:AAK64446 (EMBL:AF377339) (463 aa) fasta scores: E(): 9.4e-38, 34.74% id in 449 aa NP_939569.1 Similar to Streptomyces coelicolor SC10A5.25c protein SWALL:O54116 (EMBL:AL021529) (498 aa) fasta scores: E(): 6.5e-63, 46.93% id in 424 aa, and to Escherichia coli ATP-dependent RNA helicase RhlE or B0797 SWALL:RHLE_ECOLI (SWALL:P25888) (454 aa) fasta scores: E(): 7.6e-44, 36.06% id in 452 aa NP_939570.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_939571.1 Similar to Mycobacterium tuberculosis hypothetical 15.1 kDa protein Rv1847 or MT1895 or MTCY359.26c SWALL:YI47_MYCTU (SWALL:P95162) (140 aa) fasta scores: E(): 1.6e-08, 34.67% id in 124 aa, and to Pseudomonas aeruginosa hypothetical protein PA1618 SWALL:YG18_PSEAE (SWALL:Q9I3A4) (145 aa) fasta scores: E(): 2e-05, 32.82% id in 131 aa NP_939572.1 Similar to Mycobacterium tuberculosis magnesium and cobalt transport protein CorA or Rv1239c or MT1277 or MTV006.11c SWALL:O50455 (EMBL:AL021006) (366 aa) fasta scores: E(): 1.9e-59, 43.45% id in 359 aa, and to Escherichia coli magnesium and cobalt transport protein CorA or B3816 or Z5333 or ECS4746 SWALL:CORA_ECOLI (SWALL:P27841) (316 aa) fasta scores: E(): 3e-05, 24.03% id in 312 aa NP_939573.1 Low similarity to Agrobacterium tumefaciens StrC58 AGR_C_2998p SWALL:AAK87404 (EMBL:AE008084) (321 aa) fasta scores: E(): 2.8e-06, 31.33% id in 150 aa, and to Rhizobium meliloti hypothetical protein RB0059 or SMB20059 SWALL:CAC48459 (EMBL:AL603642) (259 aa) fasta scores: E(): 6.5e-05, 28.67% id in 143 aa NP_939574.1 Similar to Corynebacterium glutamicum NADH dehydrogenase Ndh SWALL:Q9X710 (EMBL:AJ238250) (467 aa) fasta scores: E(): 2.7e-137, 78.71% id in 451 aa, and to Escherichia coli NADH dehydrogenase Ndh or B1109 SWALL:DHNA_ECOLI (SWALL:P00393) (433 aa) fasta scores: E(): 4.9e-20, 27.08% id in 443 aa NP_939575.1 Low similarity to Mycobacterium tuberculosis cyclopropane fatty acid synthase UfaA1 or Rv0447c or MT0463 or MTV037.11C SWALL:O53732 (EMBL:AL021932) (427 aa) fasta scores: E(): 2.2e-13, 27.14% id in 431 aa, and to Agrobacterium tumefaciens StrC58 AGR_C_3601p SWALL:AAK87737 (EMBL:AE008115) (410 aa) fasta scores: E(): 5.1e-06, 21.91% id in 356 aa NP_939576.1 Similar to Salmonella typhimurium Na+-dependent transporter STM4195 SWALL:AAL23019 (EMBL:AE008896) (313 aa) fasta scores: E(): 8e-40, 41.43% id in 292 aa, and to Bacillus halodurans sodium-dependent transporter BH0858 SWALL:Q9KEJ4 (EMBL:AP001510) (323 aa) fasta scores: E(): 1.1e-38, 41.29% id in 293 aa NP_939578.1 Low similarity to Xylella fastidiosa hypothetical protein XF1327 SWALL:Q9PDQ2 (EMBL:AE003965) (189 aa) fasta scores: E(): 0.14, 25.23% id in 210 aa, and to Streptomyces coelicolor hypothetical 28.6 kDa protein 2SC10A7.34c SWALL:Q9ADM8 (EMBL:AL583945) (273 aa) fasta scores: E(): 0.23, 25.11% id in 215 aa NP_939579.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 13.2 kDa protein MT2109 SWALL:AAK46388 (EMBL:AE007062) (120 aa) fasta scores: E(): 5e-15, 43.92% id in 107 aa NP_939580.1 Similar to Mycobacterium tuberculosis hypothetical 13.0 kDa protein Rv2050 or MTV018.37 SWALL:O53492 (EMBL:AL021899) (111 aa) fasta scores: E(): 6.5e-28, 70% id in 110 aa, and to Mycobacterium leprae hypothetical protein ML1439 SWALL:Q9CC05 (EMBL:AL583922) (111 aa) fasta scores: E(): 2.9e-27, 68.18% id in 110 aa NP_939581.1 Similar to Mycobacterium smegmatis polyprenol phosphate mannosyl transferase 1 Ppm1 SWALL:Q9F408 (EMBL:AJ294477) (265 aa) fasta scores: E(): 1.6e-56, 61.6% id in 237 aa, and to Schizosaccharomyces pombe dolichol-phosphate mannosyltransferase Dpm1 or SPAC31G5.16c SWALL:O14466 (EMBL:AF007873) (236 aa) fasta scores: E(): 1.2e-24, 39.54% id in 220 aa NP_939582.1 Similar to Streptomyces coelicolor transferase 2SCG2.28c SWALL:Q9EX26 (EMBL:AL445963) (537 aa) fasta scores: E(): 2.4e-42, 37.71% id in 517 aa, and to Escherichia coli apolipoprotein N-acyltransferase Lnt or CutE or B0657 SWALL:LNT_ECOLI (SWALL:P23930) (512 aa) fasta scores: E(): 1.6e-19, 25.89% id in 533 aa NP_939583.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein NP_939584.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism NP_939585.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939586.1 Similar to Mycobacterium tuberculosis CDC1551 CobG-related protein MT2124 SWALL:AAK46404 (EMBL:AE007063) (363 aa) fasta scores: E(): 5.1e-43, 39.56% id in 369 aa NP_939587.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate NP_939588.1 Similar to Mycobacterium tuberculosis cobalamin biosynthesis protein [includes: precorrin-2 C20- methyltransferase; precorrin-3 methylase] CobIJ or Rv2066 or MT2126 or MTCY49.05 SWALL:COBI_MYCTU (SWALL:Q10677) (508 aa) fasta scores: E(): 3.6e-88, 50.7% id in 495 aa, C-terminal region to Rhodobacter capsulatus precorrin-3 methylase SWALL:O68097 (EMBL:AF010496) (245 aa) fasta scores: E(): 1.1e-34, 48.14% id in 243 aa, and N-terminal region to Pseudomonas aeruginosa precorrin-2 methyltransferase CobI or PA2904 SWALL:Q9HZU3 (EMBL:AE004716) (250 aa) fasta scores: E(): 1.4e-33, 43.3% id in 254 aa NP_939589.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 NP_939590.1 Similar to Pseudomonas denitrificans precorrin-4 C11-methyltransferase CobM SWALL:COBM_PSEDE (SWALL:P21922) (253 aa) fasta scores: E(): 5.4e-46, 55.37% id in 251 aa, and to Rhodococcus erythropolis precorrin-4 C11-methyltransferase CobM SWALL:COBM_RHOER (SWALL:Q53138) (249 aa) fasta scores: E(): 3.4e-57, 61.04% id in 249 aa NP_939591.1 Similar to Mycobacterium tuberculosis precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL or Rv2072c or MT2132 or MTCY49.11c SWALL:COBL_MYCTU (SWALL:Q10671) (390 aa) fasta scores: E(): 5.8e-57, 44.22% id in 398 aa, and to Pseudomonas denitrificans precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL SWALL:COBL_PSEDE (SWALL:P21921) (413 aa) fasta scores: E(): 1.5e-47, 39.5% id in 405 aa NP_939592.1 probable dehydrogenase NP_939593.1 Similar to Mycobacterium tuberculosis probable dipeptidase Rv2089c or MT2150 or MTCY49.29c SWALL:YK89_MYCTU (SWALL:Q10698) (375 aa) fasta scores: E(): 3.1e-56, 49.86% id in 377 aa, and to Halobacterium sp probable peptidase PepQ1 or Vng0723g SWALL:Q9HRF6 (EMBL:AE005016) (369 aa) fasta scores: E(): 2.2e-37, 38.62% id in 378 aa NP_939594.1 Similar to Mycobacterium tuberculosis probable helicase HelY or Rv2092c or MT2153 or MTCY49.30c SWALL:HELY_MYCTU (SWALL:Q10701) (906 aa) fasta scores: E(): 4.5e-69, 48.87% id in 933 aa, and to Synechocystis sp antiviral protein Ski2 or SLR0451 SWALL:P74686 (EMBL:D90917) (1006 aa) fasta scores: E(): 2.3e-27, 29.42% id in 1040 aa NP_939595.1 Similar to Mycobacterium leprae tRNA/rRNA methyltransferase ML0419 SWALL:Q9CCU7 (EMBL:AL583918) (158 aa) fasta scores: E(): 7.7e-35, 58.71% id in 155 aa, and to Escherichia coli hypothetical tRNA/rRNA methyltransferase YibK or B3606 SWALL:YIBK_ECOLI (SWALL:P33899) (157 aa) fasta scores: E(): 3.3e-28, 50% id in 152 aa NP_939596.1 Similar to, although longer in its C-terminal region than Mycobacterium tuberculosis Sec-independent protein translocase TatC homolog or Rv2093c or MT2154 or MTCY49.33c SWALL:TATC_MYCTU (SWALL:Q10702) (308 aa) fasta scores: E(): 1.6e-54, 56.55% id in 290 aa, and to Escherichia coli Sec-independent protein translocase TatC or MttB or B3839 or Z5360 or ECS4768 SWALL:TATC_ECOLI (SWALL:P27857) (258 aa) fasta scores: E(): 9.3e-14, 28.04% id in 271 aa NP_939597.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes NP_939598.1 Similar to Rhodococcus erythropolis ORF11 SWALL:P72265 (EMBL:Z82004) (326 aa) fasta scores: E(): 1.3e-24, 31.42% id in 315 aa, and to Mycobacterium tuberculosis hypothetical 33.8 kDa protein Rv2095c precursor or MT2156 or MTCY49.35c SWALL:YK95_MYCTU (SWALL:Q10704) (316 aa) fasta scores: E(): 3.4e-24, 31.57% id in 304 aa NP_939599.1 Similar to Rhodococcus erythropolis ORF10 SWALL:P72264 (EMBL:Z82004) (330 aa) fasta scores: E(): 6.6e-20, 31.42% id in 331 aa, and to Mycobacterium leprae hypothetical 35.4 kDa protein ML1329 or MLCB2533.25 or B2126_C3_266 SWALL:YK96_MYCLE (SWALL:P54076) (331 aa) fasta scores: E(): 2.8e-19, 30.42% id in 332 aa NP_939600.1 Similar to Rhodococcus erythropolis ORF9 SWALL:P72270 (EMBL:Z82005) (447 aa) fasta scores: E(): 8.7e-96, 55.7% id in 456 aa, and to Mycobacterium tuberculosis hypothetical 51.4 kDa protein Rv2097c or MT2158 or MTCY49.37c SWALL:YK97_MYCTU (SWALL:Q10706) (452 aa) fasta scores: E(): 8.8e-96, 54.56% id in 460 aa NP_939601.1 Similar to Mycobacterium smegmatis hypothetical 7.0 kDa protein PrcS SWALL:O30517 (EMBL:AF009645) (64 aa) fasta scores: E(): 3.2e-07, 60.71% id in 56 aa, and to Rhodococcus erythropolis similar to ORF7 SWALL:Q53082 (EMBL:U26422) (64 aa) fasta scores: E(): 1.6e-06, 55% id in 60 aa NP_939602.1 Similar to Rhodococcus erythropolis similar to ORF6 SWALL:Q53081 (EMBL:U26422) (499 aa) fasta scores: E(): 2.2e-72, 48.04% id in 512 aa, and to Frankia spACN14A/ts-r. hypothetical 56.4 kDa protein SWALL:Q9RAW9 (EMBL:AF142435) (505 aa) fasta scores: E(): 3.8e-51, 47.36% id in 494 aa NP_939603.1 Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa NP_939604.1 Similar to Rhodococcus erythropolis hypothetical 35.2 kDa protein SWALL:Q9ZG14 (EMBL:AF088800) (324 aa) fasta scores: E(): 7.9e-71, 65.45% id in 275 aa, and to Mycobacterium tuberculosis hypothetical 30.1 kDa protein Rv2118c or MTCY261.14c SWALL:O33253 (EMBL:Z97559) (280 aa) fasta scores: E(): 2.6e-62, 58.27% id in 278 aa NP_939605.1 catalyzes the removal of amino acids from the N termini of peptides NP_939606.1 Similar to Mycobacterium tuberculosis hypothetical 30.9 kDa protein Rv2119 or MTCY261.15 SWALL:O33254 (EMBL:Z97559) (278 aa) fasta scores: E(): 9e-48, 48.16% id in 272 aa, and to Streptomyces coelicolor hypothetical 31.9 kDa protein SCI41.36 SWALL:Q9RJ55 (EMBL:AL132648) (284 aa) fasta scores: E(): 2.8e-45, 47.34% id in 264 aa NP_939607.1 Low similarity to Caulobacter crescentus virulence-associated protein, CC2867 SWALL:Q9A4G7 (EMBL:AE005951) (104 aa) fasta scores: E(): 0.00032, 29.26% id in 82 aa, and to Bacteroides nodosus virulence-associated protein I VapI SWALL:VAPI_BACNO (SWALL:Q46560) (108 aa) fasta scores: E(): 0.0023, 27.58% id in 87 aa NP_939608.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate NP_939609.1 catalyzes the formation of fumarate from aspartate NP_939610.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB NP_939611.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors NP_939612.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis NP_939613.1 Similar to Streptomyces coelicolor hydrolase SCI46.01c SWALL:Q9EWH4 (EMBL:AL499607) (233 aa) fasta scores: E(): 4.7e-15, 32.8% id in 189 aa, and to Rhodobacter capsulatus CbbY protein SWALL:CBBY_RHOCA (SWALL:O33513) (227 aa) fasta scores: E(): 1.6e-11, 33.65% id in 205 aa NP_939614.1 Similar to Mycobacterium tuberculosis 5-methyltetrahydrofolate--homocysteine methyltransferase MetH or Rv2124c or MTCY261.20c SWALL:METH_MYCTU (SWALL:O33259) (1192 aa) fasta scores: E(): 0, 70.85% id in 1194 aa, and to Escherichia coli 5-methyltetrahydrofolate--homocysteine methyltransferase MetH or B4019 SWALL:METH_ECOLI (SWALL:P13009) (1226 aa) fasta scores: E(): 2.8e-92, 32.4% id in 1225 aa NP_939615.1 Similar to the plasmid borne Corynebacterium striatum YtpA SWALL:Q9FB56 (EMBL:AF024666) (132 aa) fasta scores: E(): 7.6e-12, 37.19% id in 121 aa NP_939616.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_939617.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell NP_939618.1 Similar to Corynebacterium striatum LppL SWALL:Q9EVJ8 (EMBL:AF024666) (350 aa) fasta scores: E(): 4.3e-35, 34.21% id in 342 aa NP_939619.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors NP_939620.1 Similar to Corynebacterium striatum YbhB SWALL:Q9FB60 (EMBL:AF024666) (177 aa) fasta scores: E(): 5.1e-42, 60.67% id in 178 aa, and to Vibrio cholerae hypothetical protein VC1075 SWALL:Q9KT30 (EMBL:AE004189) (180 aa) fasta scores: E(): 1.2e-19, 41.1% id in 163 aa NP_939621.1 Similar to, although shorter in its N-terminal region than Escherichia coli possible transposase of IS1353 YahA SWALL:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 2.5e-62, 41.59% id in 464 aa, and similar to, although longer in its N-terminal region than Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SWALL:INSK_ECOLI (SWALL:P19769) (283 aa) fasta scores: E(): 2.6e-35, 38.62% id in 277 aa NP_939622.1 Similar to, although sorter in its N-terminal region than Vibrio cholerae thiosulfate sulfurtransferase SseA, VCA0620 SWALL:Q9KLX1 (EMBL:AE004392) (276 aa) fasta scores: E(): 6.9e-30, 38.72% id in 235 aa, and than Escherichia coli O157:H7 3-mercaptopyruvate sulfurtransferase SseA or Z3788 or ECS3387 SWALL:AAG57635 (EMBL:AE005482) (334 aa) fasta scores: E(): 2e-27, 38.65% id in 238 aa. Note: In the database matches for this CDS, the non-catalitic domain lies in the N-terminal region of the protein, hence this CDS being shorter in that region should not suppose a change in the possible catalytic activity, mostly if we consider that the possibly active-site residue 204 (cysteine) lies within the almost conserved region (CGCGVTA in E. coli and CGSRVTA in C. diphtheriae) possibly responsible for substrate specificity NP_939623.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins NP_939624.1 MDM; functions in conversion of succinate to propionate NP_939625.1 Similar to Mycobacterium tuberculosis probable methylmalonyl-CoA mutase small subunit MutA or Rv1492 or MT1539 or MTCY277.14 SWALL:MUTA_MYCTU (SWALL:P71773) (615 aa) fasta scores: E(): 1.5e-69, 43.15% id in 621 aa, and to Porphyromonas gingivalis methylmalonyl-CoA mutase small subunit MutA or McmA SWALL:MUTA_PORGI (SWALL:Q59676) (617 aa) fasta scores: E(): 4.9e-31, 30.73% id in 628 aa NP_939626.1 Similar to Mycobacterium tuberculosis hypothetical 26.6 kDa protein Rv1491c or MT1538 or MTCY277.13c SWALL:YE91_MYCTU (SWALL:P71772) (252 aa) fasta scores: E(): 2.5e-24, 36.09% id in 205 aa, and to Streptomyces coelicolor integral membrane protein 2SCG61.05c SWALL:Q9K410 (EMBL:AL359949) (258 aa) fasta scores: E(): 2.3e-10, 28.09% id in 210 aa NP_939628.1 Similar to Mycobacterium tuberculosis hypothetical 41.2 kDa protein Rv1488 or MT1533.2 or MTCY277.09 SWALL:YE88_MYCTU (SWALL:P71768) (381 aa) fasta scores: E(): 1.4e-79, 62.53% id in 363 aa, and to Pyrococcus abyssi stomatin-like protein PAB1324 SWALL:Q9UYE4 (EMBL:AJ248288) (299 aa) fasta scores: E(): 2.7e-35, 42.65% id in 279 aa NP_939629.1 Similar to Mycobacterium avium MAV145 SWALL:O07404 (EMBL:AF002133) (145 aa) fasta scores: E(): 2.2e-11, 35.25% id in 139 aa, and to Streptomyces coelicolor integral membrane protein SC2H12.25 SWALL:Q9K459 (EMBL:AL359215) (146 aa) fasta scores: E(): 7.4e-11, 33.08% id in 136 aa NP_939630.1 Similar to Streptomyces coelicolor hypothetical 29.4 kDa protein SCC77.24 SWALL:Q9RDD4 (EMBL:AL136503) (274 aa) fasta scores: E(): 1.3e-46, 50.57% id in 259 aa, and to Mycobacterium tuberculosis hypothetical 30.5 kDa protein Rv2033c or MTV018.20 SWALL:O53477 (EMBL:AL021899) (280 aa) fasta scores: E(): 6.7e-37, 46.78% id in 280 aa NP_939632.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_939633.1 Similar to Mycobacterium tuberculosis hypothetical 49.8 kDa protein Rv1477 or MT1524 or MTV007.24 SWALL:O53168 (EMBL:AL021184) (472 aa) fasta scores: E(): 3.5e-21, 31.88% id in 577 aa, and C-terminal half similar to the whole length of Mycobacterium tuberculosis hypothetical invasion protein Inv1 SWALL:O33171 (EMBL:AF006054) (277 aa) fasta scores: E(): 1e-17, 39.5% id in 281 aa. Note: Contains two possible colied-coil region at residues 102..130 and 182..360 NP_939634.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939635.2 Catalyzes the conversion of citrate to isocitrate NP_939636.1 Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, TetR family MT1521 SWALL:AAK45786 (EMBL:AE007021) (187 aa) fasta scores: E(): 1.8e-40, 60.42% id in 187 aa, and to Deinococcus radiodurans transcriptional regulator, TetR family DR2148 SWALL:Q9RSH6 (EMBL:AE002049) (204 aa) fasta scores: E(): 9e-06, 30.48% id in 164 aa NP_939637.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group NP_939638.1 ACT domain-containing protein NP_939639.1 Similar to Streptococcus pneumoniae hypothetical protein SP0239 SWALL:AAK74419 (EMBL:AE007336) (445 aa) fasta scores: E(): 8e-101, 65.91% id in 446 aa, and to Neisseria meningitidis hypothetical protein NMA1908 SWALL:Q9JTA4 (EMBL:AL162757) (451 aa) fasta scores: E(): 4.7e-98, 62.1% id in 446 aa NP_939640.1 Similar to Bacillus subtilis hypothetical YxlE SWALL:P94373 (EMBL:D83026) (62 aa) fasta scores: E(): 0.028, 31.03% id in 58 aa NP_939641.1 Similar to Mycobacterium tuberculosis CDC1551 ABC transporter, ATP-binding protein MT1519 SWALL:AAK45784 (EMBL:AE007021) (542 aa) fasta scores: E(): 2.2e-114, 70.95% id in 544 aa, and to Bacillus halodurans ABC transporter BH2025 SWALL:Q9KBA3 (EMBL:AP001514) (539 aa) fasta scores: E(): 6.5e-33, 32.07% id in 505 aa NP_939642.1 Similar to Mycobacterium tuberculosis hypothetical 12.4 kDa protein Rv1466 or MTV007.13 SWALL:O53157 (EMBL:AL021184) (115 aa) fasta scores: E(): 6.7e-24, 67.3% id in 104 aa, and to Deinococcus radiodurans conserved hypothetical protein DR2165 SWALL:Q9RSF9 (EMBL:AE002050) (149 aa) fasta scores: E(): 1.1e-13, 43.59% id in 117 aa NP_939643.1 Similar to Mycobacterium tuberculosis CDC1551 nitrogen fixation protein NifU-related protein MT1512 SWALL:AAK45776 (EMBL:AE007020) (162 aa) fasta scores: E(): 2.6e-35, 63.69% id in 146 aa, and to Bacillus subtilis NifU-like protein NifU SWALL:NIFU_BACSU (SWALL:O32163) (147 aa) fasta scores: E(): 3.7e-18, 44.21% id in 147 aa NP_939644.1 Similar to Mycobacterium tuberculosis probable cysteine desulfurase Csd or Rv1464 or MT1511 or MTV007.11 SWALL:CSD_MYCTU (SWALL:O53155) (417 aa) fasta scores: E(): 1.4e-99, 63.81% id in 409 aa, and to Escherichia coli selenocysteine lyase CsdB or SufS or B1680 SWALL:CSDB_ECOLI (SWALL:P77444) (406 aa) fasta scores: E(): 1.4e-63, 41.7% id in 410 aa NP_939645.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding subunit SCC22.04c SWALL:Q9XAD4 (EMBL:AL096839) (254 aa) fasta scores: E(): 4.3e-58, 70.4% id in 250 aa, and to Mycobacterium tuberculosis hypothetical 28.8 kDa protein Rv1463 or MTV007.10 SWALL:O53154 (EMBL:AL021184) (266 aa) fasta scores: E(): 8.8e-59, 70% id in 250 aa, and to Staphylococcus aureus (strain N315) SA0774 protein or SAV0842 SWALL:BAB57004 (EMBL:AP003131) (253 aa) fasta scores: E(): 1.7e-44, 58.63% id in 249 aa NP_939646.1 Similar to Mycobacterium tuberculosis hypothetical 42.5 kDa protein Rv1462 or MT1509 or MTV007.09 SWALL:YE62_MYCTU (SWALL:O53153) (397 aa) fasta scores: E(): 7.7e-84, 56.05% id in 380 aa, and to Streptomyces coelicolor conserved hypothetical protein SCC22.06c SWALL:Q9XAD2 (EMBL:AL096839) (394 aa) fasta scores: E(): 6.1e-75, 52.86% id in 367 aa NP_939647.1 Similar to Streptomyces coelicolor conserved hypothetical protein SCC22.07c SWALL:Q9XAD1 (EMBL:AL096839) (473 aa) fasta scores: E(): 1.9e-154, 82.78% id in 459 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0778 or SAV0846 SWALL:Q99VF9 (EMBL:AP003131) (465 aa) fasta scores: E(): 1.7e-123, 65.14% id in 459 aa NP_939648.1 Similar to Mycobacterium tuberculosis hypothetical 29.2 kDa protein Rv1460 or MTV007.07 SWALL:O53151 (EMBL:AL021184) (278 aa) fasta scores: E(): 3.4e-38, 46.25% id in 240 aa, and to Streptomyces coelicolor DNA-binding protein scc22.08C SWALL:Q9XAD0 (EMBL:AL096839) (252 aa) fasta scores: E(): 9e-27, 42.35% id in 229 aa NP_939650.1 Similar to Mycobacterium tuberculosis hypothetical 62.7 kDa protein Rv1459c or MT1506 or MTV007.06c SWALL:AAK45770 (EMBL:AL021184) (591 aa) fasta scores: E(): 2.6e-33, 36.63% id in 546 aa, and to Mycobacterium tuberculosis membrane protein Rv2174 or MT2230 or MTV021.07 SWALL:O53508 (EMBL:AL021957) (516 aa) fasta scores: E(): 2.1e-18, 30.6% id in 464 aa, and low similarity to Rhizobium meliloti cytochrome C oxidase polypeptide I transmembrane protein CtaD or R00905 or SMC00010 SWALL:Q92RG9 (EMBL:AL591785) (562 aa) fasta scores: E(): 1.6, 22.94% id in 475 aa NP_939651.1 Similar to Mycobacterium tuberculosis ABC-transporter ATP-binding protein Rv1458c or MTV007.05c SWALL:O53149 (EMBL:AL021184) (313 aa) fasta scores: E(): 2e-48, 50.32% id in 304 aa, and to Streptomyces peucetius daunorubicin resistance ATP-binding protein DrrA SWALL:DRRA_STRPE (SWALL:P32010) (330 aa) fasta scores: E(): 1.5e-24, 34.09% id in 305 aa NP_939652.1 Similar to Mycobacterium tuberculosis hypothetical 27.4 kDa protein Rv1457c or MTV007.04c SWALL:O86349 (EMBL:AL021184) (261 aa) fasta scores: E(): 1.5e-31, 41.47% id in 258 aa, and to Mycobacterium smegmatis hypothetical 24.4 kDa protein SWALL:O87317 (EMBL:AF027770) (236 aa) fasta scores: E(): 1.1e-23, 37.55% id in 237 aa NP_939653.1 Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1456c or MT1503 or MTV007.03C SWALL:AAK45767 (EMBL:AL021184) (311 aa) fasta scores: E(): 3.7e-43, 43.75% id in 304 aa, and to Streptomyces coelicolor integral membrane transport protein SCC22.12 SWALL:Q9XAC6 (EMBL:AL096839) (356 aa) fasta scores: E(): 6.9e-24, 33.01% id in 312 aa, and low similarity to Bacillus firmus cytochrome aa3 controlling protein ctaA SWALL:CTAA_BACFI (SWALL:Q04443) (297 aa) fasta scores: E(): 0.0021, 21.42% id in 266 aa NP_939654.1 converts protoheme IX and farnesyl diphosphate to heme O NP_939655.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_939656.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate NP_939657.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_939658.1 Similar to Streptomyces coelicolor hypothetical 37.7 kDa protein SCC22.20 SWALL:Q9XAB8 (EMBL:AL096839) (351 aa) fasta scores: E(): 1.5e-36, 41.82% id in 318 aa, and to Mycobacterium tuberculosis hypothetical 32.7 kDa protein OpcA or Rv1446c or MT1493 or MTCY493.08 SWALL:AAK45756 (EMBL:Z95844) (303 aa) fasta scores: E(): 9.5e-35, 39.3% id in 318 aa NP_939659.1 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone NP_939660.1 Similar to Corynebacterium glutamicum protein-export membrane protein SecG SWALL:SECG_CORGL (SWALL:Q9Z469) (77 aa) fasta scores: E(): 7.3e-22, 82.89% id in 76 aa, and to Escherichia coli protein-export membrane protein SecG or B3175 or Z4537 or ECS4054 SWALL:SECG_ECOLI (SWALL:P33582) (110 aa) fasta scores: E(): 0.55, 26.02% id in 73 aa NP_939661.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_939662.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_939663.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_939664.1 Similar to Mycobacterium tuberculosis hypothetical 34.9 kDa protein CY21B4.41 Rv1423 or MT1466 or MTCY21B4.41 or MTCY493.31c SWALL:AAK45731 (EMBL:Z80108) (327 aa) fasta scores: E(): 4.2e-71, 61.84% id in 325 aa, and to Streptomyces coelicolor WhiA SWALL:Q9S4Y1 (EMBL:AF106003) (330 aa) fasta scores: E(): 3.7e-67, 57.53% id in 325 aa NP_939665.1 Similar to Mycobacterium leprae hypothetical protein ML0564 SWALL:Q9CCN9 (EMBL:AL583918) (359 aa) fasta scores: E(): 2.7e-63, 57.6% id in 309 aa, and to Escherichia coli hypothetical protein YbhK or B0780 SWALL:YBHK_ECOLI (SWALL:P75767) (302 aa) fasta scores: E(): 1.5e-11, 31.95% id in 291 aa NP_939666.1 Similar to Mycobacterium tuberculosis hypothetical 32.9 kDa protein Rv1421 or MT1464 or MTCY21B4.39 SWALL:YE21_MYCTU (SWALL:P71690) (301 aa) fasta scores: E(): 9e-52, 47.82% id in 299 aa, and to Clostridium acetobutylicum predicted P-loop containing kinase, similar to B.subtilis YvcJ CAC0511 SWALL:AAK78491 (EMBL:AE007566) (294 aa) fasta scores: E(): 4.8e-43, 44.21% id in 285 aa NP_939667.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_939668.1 Similar to Corynebacterium ammoniagenes RibX protein SWALL:O24754 (EMBL:AB003693) (184 aa) fasta scores: E(): 1.3e-34, 45.98% id in 187 aa, and to Mycobacterium leprae membrane protein ML0561 SWALL:Q9CCP2 (EMBL:AL583918) (156 aa) fasta scores: E(): 2.3e-15, 37.58% id in 141 aa NP_939669.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_939670.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate NP_939671.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_939672.1 Similar to Corynebacterium ammoniagenes riboflavin biosynthesis protein [includes: riboflavin-specific deaminase and uracil reductase] RibD or RibG SWALL:RIBD_CORAM (SWALL:O24750) (337 aa) fasta scores: E(): 4.7e-50, 46.89% id in 322 aa, and to Bacillus subtilis riboflavin biosynthesis protein RibD or RibG SWALL:RIBD_BACSU (SWALL:P17618) (361 aa) fasta scores: E(): 2.8e-22, 34.76% id in 325 aa NP_939673.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_939674.1 Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa NP_939675.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_939676.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_939677.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_939678.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_939679.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine NP_939680.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_939681.1 Essential for recycling GMP and indirectly, cGMP NP_939682.1 Similar to Mycobacterium smegmatis integration host factor MihF SWALL:P96802 (EMBL:U75344) (105 aa) fasta scores: E(): 7.1e-21, 72.38% id in 105 aa, and to Mycobacterium tuberculosis hypothetical 20.8 kDa protein CY21B4.05 Rv1388 or MT1433 or MTCY21B4.05 SWALL:AAK45698 (EMBL:Z80108) (111 aa) fasta scores: E(): 3.8e-21, 74.75% id in 103 aa NP_939683.1 OMP decarboxylase; OMPDCase; OMPdecase; type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_939684.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_939685.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_939686.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_939687.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_939688.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity NP_939689.1 C-terminal region similar to Mycobacterium tuberculosis hypothetical 31.7 kDa protein Rv2216 or MT2273 or MTCY190.27 SWALL:YM16_MYCTU (SWALL:Q10403) (301 aa) fasta scores: E(): 4e-32, 36.51% id in 293 aa, and N-terminal region to Bacillus halodurans BH1480 protein SWALL:Q9KCT9 (EMBL:AP001512) (144 aa) fasta scores: E(): 0.047, 27.35% id in 106 aa NP_939692.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_939693.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_939694.1 Similar to Mycobacterium tuberculosis hypothetical 38.8 kDa protein PepQ or Rv2535c or MTCY159.21 SWALL:P95018 (EMBL:Z83863) (372 aa) fasta scores: E(): 2.3e-52, 45.64% id in 344 aa, and to Bacillus halodurans xaa-pro dipeptidase BH2800 SWALL:Q9K950 (EMBL:AP001516) (355 aa) fasta scores: E(): 1.2e-43, 41.57% id in 356 aa NP_939695.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_939696.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_939697.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_939698.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_939699.1 Similar to the C-terminal region of Aeromonas salmonicida type 4 prepilin-like proteins leader peptide processing enzyme [includes: leader peptidase TapD or PilD] SWALL:LEP4_AERSA (SWALL:O68964) (291 aa) fasta scores: E(): 0.012, 26.71% id in 146 aa NP_939700.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_939701.1 Similar to, although shorter in its N-terminal region than Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2630 SWALL:AAK46942 (EMBL:AE007097) (417 aa) fasta scores: E(): 2.3e-52, 41.38% id in 389 aa, and similar to Haemophilus influenzae hypothetical protein HI0457 SWALL:YCEG_HAEIN (SWALL:P44720) (347 aa) fasta scores: E(): 7.2e-14, 28.76% id in 365 aa NP_939702.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_939703.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_939704.1 Similar to Mycobacterium tuberculosis hypothetical 47.5 kDa protein Rv2559c or MT2636 or MTCY9C4.09 SWALL:YP59_MYCTU (SWALL:Q50739) (452 aa) fasta scores: E(): 3.1e-95, 66.59% id in 455 aa, and to Streptomyces coelicolor conserved ATP/GTP binding protein SC9C5.30c SWALL:Q9KXP4 (EMBL:AL357523) (451 aa) fasta scores: E(): 4.3e-84, 63.52% id in 414 aa NP_939706.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_939707.1 Similar to Mycobacterium tuberculosis hypothetical 30.8 kDa protein Rv2575 or MT2651 or MTCY227.26c SWALL:YP75_MYCTU (SWALL:Q50646) (293 aa) fasta scores: E(): 1.8e-45, 44.74% id in 295 aa, and to Agrobacterium tumefaciens strC58 AGR_C_3948p SWALL:AAK87920 (EMBL:AE008134) (305 aa) fasta scores: E(): 1.1e-31, 36.66% id in 300 aa NP_939708.1 Similar to Streptomyces coelicolor bifunctional protein SCBAC20F6.07 SWALL:Q9ADE3 (EMBL:AL590942) (800 aa) fasta scores: E(): 5e-37, 39% id in 700 aa, and to Streptomyces griseus hypothetical 77.7 kDa protein SWALL:BAB64333 (EMBL:AB056583) (724 aa) fasta scores: E(): 2.5e-32, 34.85% id in 680 aa NP_939709.1 Similar to Bacillus subtilis hypothetical 84.1 kDa protein in hemY-gltT intergenic region YhgE SWALL:YHGE_BACSU (SWALL:P32399) (775 aa) fasta scores: E(): 5.1e-22, 25.23% id in 761 aa, and to Lactococcus lactis hypothetical protein YjaE or LL0882 SWALL:Q9CH57 (EMBL:AE006322) (799 aa) fasta scores: E(): 6.5e-20, 24.68% id in 790 aa NP_939711.1 Similar to Streptomyces coelicolor TetR family transcriptional regulator SCF6.16 SWALL:Q9RJL5 (EMBL:AL121849) (194 aa) fasta scores: E(): 6.8e-06, 25.53% id in 188 aa, and to Rhizobium loti probable transcription regulator MLL1924 SWALL:Q98JI8 (EMBL:AP002998) (205 aa) fasta scores: E(): 1.1e-05, 25.77% id in 194 aa NP_939712.1 Similar to Pseudomonas aeruginosa L-serine dehydratase SdaB or PA5379 SWALL:Q9HTI5 (EMBL:AE004950) (458 aa) fasta scores: E(): 3.5e-84, 53.99% id in 463 aa, and to Escherichia coli L-serine dehydratase 1 SdaA or B1814 SWALL:SDHL_ECOLI (SWALL:P16095) (454 aa) fasta scores: E(): 3e-70, 49.24% id in 461 aa NP_939713.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_939714.1 Similar to Streptomyces coelicolor possible hydrolase SC9C5.33c SWALL:Q9KXP1 (EMBL:AL357523) (235 aa) fasta scores: E(): 6.5e-25, 40.35% id in 223 aa, and to Escherichia coli hypothetical protein YcbL or B0927 SWALL:YCBL_ECOLI (SWALL:P75849) (215 aa) fasta scores: E(): 3.7e-23, 36.79% id in 212 aa NP_939715.1 Similar to Escherichia coli thiol peroxidase Tpx or B1324 or Z2452 or ECS1903 SWALL:TPX_ECOLI (SWALL:P37901) (167 aa) fasta scores: E(): 5.8e-35, 61.11% id in 162 aa, and to Pseudomonas aeruginosa probable thiol peroxidase Tpx or PA2532 SWALL:TPX_PSEAE (SWALL:P57668) (165 aa) fasta scores: E(): 4.8e-32, 55.75% id in 165 aa NP_939716.1 Similar to Mycobacterium tuberculosis probable peptidyl-prolyl cis-trans isomerase B PpiB or Ppi or Rv2582 or MT2659 or MTCY227.19c SWALL:PPIB_MYCTU (SWALL:Q50639) (308 aa) fasta scores: E(): 5.5e-37, 46.23% id in 292 aa, and to Streptomyces coelicolor peptidyl-prolyl cis-trans isomerase SC9C5.34 SWALL:Q9KXP0 (EMBL:AL357523) (277 aa) fasta scores: E(): 3.5e-26, 37.5% id in 288 aa NP_939718.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939719.1 Similar to, although shorter than Escherichia coli possible transposase of IS1353 YahA SWALL:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 1.4e-62, 41.59% id in 464 aa, and similar in its C-terminal region to Escherichia coli transposase InsK for insertion sequence element IS150 InsK or B3558 SWALL:INSK_ECOLI (SWALL:P19769) (283 aa) fasta scores: E(): 1.4e-35, 38.98% id in 277 aa NP_939720.1 Similar to Corynebacterium glutamicum GTP pyrophosphokinase RelA or Rel SWALL:RELA_CORGL (SWALL:O87331) (760 aa) fasta scores: E(): 0, 86.05% id in 760 aa, and to Escherichia coli GTP pyrophosphokinase RelA or B2784 or Z4099 or ECS3644 SWALL:RELA_ECOLI (SWALL:P11585) (744 aa) fasta scores: E(): 4.1e-97, 36.54% id in 684 aa, and to Streptomyces coelicolor GTP pyrophosphokinase RelA or SCL2.03c SWALL:RELA_STRCO (SWALL:P52560) (847 aa) fasta scores: E(): 7.3e-90, 58.33% id in 768 aa NP_939721.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_939722.1 Similar to Corynebacterium glutamicum dipeptide-binding protein DciaE SWALL:O87329 (EMBL:AF038651) (502 aa) fasta scores: E(): 4e-83, 48.61% id in 434 aa, and to Mycobacterium tuberculosis hypothetical lipoprotein Rv2585c precursor or MT2662 or MTCY227.16 SWALL:YP85_MYCTU (SWALL:Q50636) (557 aa) fasta scores: E(): 7.1e-30, 29.09% id in 574 aa NP_939723.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_939724.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane NP_939726.1 Similar to Corynebacterium glutamicum hypothetical 13.5 kDa protein SWALL:Q9AE08 (EMBL:AF038651) (121 aa) fasta scores: E(): 7.2e-10, 34.83% id in 89 aa, and to Mycobacterium tuberculosis hypothetical 13.0 kDa protein Rv2588c precursor or MT2665 or MTCY227.13 SWALL:YP88_MYCTU (SWALL:Q50633) (115 aa) fasta scores: E(): 5.9e-05, 37.77% id in 90 aa NP_939727.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_939728.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_939729.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity NP_939730.1 Highly similar to Corynebacterium glutamicum hypothetical structural protein YfcA SWALL:Q9AE12 (EMBL:AF038651) (251 aa) fasta scores: E(): 2.7e-76, 83.53% id in 249 aa, and to Escherichia coli protein YebC in 249 aa NP_939731.1 Similar to Mycobacterium tuberculosis TesB or TesB2 or Rv2605c or MTCY01A10.28 SWALL:O06209 (EMBL:Z95387) (281 aa) fasta scores: E(): 1.9e-49, 50.17% id in 279 aa, and to Escherichia coli acyl-CoA thioesterase II TesB or B0452 or Z0564 or ECS0506 SWALL:TESB_ECOLI (SWALL:P23911) (285 aa) fasta scores: E(): 3e-20, 37.27% id in 279 aa NP_939733.1 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A NP_939734.1 Similar to Bacillus sphaericus 8-amino-7-oxononanoate synthase BioF SWALL:BIOF_BACSH (SWALL:P22806) (389 aa) fasta scores: E(): 8.9e-47, 40.95% id in 376 aa, and to Escherichia coli 8-amino-7-oxononanoate synthase BioF or B0776 SWALL:BIOF_ECOLI (SWALL:P12998) (384 aa) fasta scores: E(): 9.8e-39, 37.39% id in 353 aa NP_939735.1 Similar to the N-terminal region of Mycobacterium tuberculosis CDC1551 MutT/NudIX family protein MT2684 SWALL:AAK47000 (EMBL:AE007101) (351 aa) fasta scores: E(): 1.2e-06, 42.2% id in 154 aa, and to Streptomyces coelicolor hypothetical 19.8 kDa protein SCL2.14c SWALL:Q9L285 (EMBL:AL137778) (180 aa) fasta scores: E(): 0.0099, 35.88% id in 170 aa NP_939736.1 Similar to Streptomyces coelicolor sugar transferase SCL2.15c SWALL:Q9L284 (EMBL:AL137778) (387 aa) fasta scores: E(): 3.5e-45, 49.06% id in 375 aa, and to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT2685 SWALL:AAK47001 (EMBL:AE007101) (378 aa) fasta scores: E(): 9.2e-42, 47.89% id in 380 aa NP_939737.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA NP_939738.1 Similar to Mycobacterium tuberculosis CDC1551 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, MT2687 SWALL:AAK47003 (EMBL:AE007101) (217 aa) fasta scores: E(): 6.9e-34, 48.29% id in 205 aa, and to Mycobacterium smegmatis phosphatidylinositol synthase PgsA SWALL:Q9F7Y9 (EMBL:AF265558) (222 aa) fasta scores: E(): 8.7e-31, 47% id in 200 aa NP_939739.1 Similar to Mycobacterium leprae hypothetical protein ML0455 SWALL:Q9CCU0 (EMBL:AL583918) (206 aa) fasta scores: E(): 6.3e-43, 61.49% id in 174 aa, and to Mycobacterium leprae hypothetical 20.7 kDa protein MLCl581.17c SWALL:O07150 (EMBL:Z96801) (186 aa) fasta scores: E(): 4.1e-42, 62.13% id in 169 aa NP_939740.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_939741.1 Similar to Yersinia pestis hypothetical protein YPO1856 SWALL:Q8ZF62 (EMBL:AJ414150) (434 aa) fasta scores: E(): 8.7e-30, 33.74% id in 406 aa, and to Escherichia coli hypothetical protein YcdB precursor or B1019 SWALL:YCDB_ECOLI (SWALL:P31545) (423 aa) fasta scores: E(): 2.4e-29, 32.22% id in 419 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRGFLT) at the N-terminal region NP_939742.1 Low similarity to Vibrio cholerae hypothetical protein VCA0037 SWALL:Q9KNC8 (EMBL:AE004347) (150 aa) fasta scores: E(): 9.6e-09, 34.09% id in 132 aa, and to Rhizobium loti MLL3326 protein SWALL:Q98GH4 (EMBL:AP003001) (179 aa) fasta scores: E(): 3.1e-05, 29.45% id in 146 aa NP_939744.1 Similar to Mycobacterium leprae hypothetical 29.0 kDa protein ML1340 or MLC1351.23 TR:O05684 (EMBL:Z95117) (268 aa) fasta scores: E(): 1.4e-12, 30.97% id in 226 aa, and to Mycobacterium tuberculosis hypothetical 27.7 kDa protein CY441.40 Rv2671 or MT2745 or MTCY441.40 TR:AAK47060 (EMBL:Z80225) (239 aa) fasta scores: E(): 9.8e-12, 29.27% id in 222 aa NP_939745.1 Similar to Mycobacterium tuberculosis CDC1551 PilB-related protein MT2748 TR:AAK47063 (EMBL:AE007105) (136 aa) fasta scores: E(): 6.2e-39, 70.67% id in 133 aa, and to Streptomyces coelicolor oxidoreductase SC9B1.08 TR:Q9X828 (EMBL:AL049727) (135 aa) fasta scores: E(): 4.3e-33, 67.74% id in 124 aa NP_939746.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2750 TR:AAK47065 (EMBL:AE007105) (231 aa) fasta scores: E(): 3e-55, 59.3% id in 231 aa, and to Streptomyces coelicolor hypothetical 28.1 kDa protein Sc1B5.02 TR:O69830 (EMBL:AL023517) (243 aa) fasta scores: E(): 5.5e-48, 54.7% id in 223 aa NP_939747.1 Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv2680 or MT2754 or MTV010.04 TR:O86317 (EMBL:Z96072) (210 aa) fasta scores: E(): 2.7e-38, 56.59% id in 182 aa, and to Streptomyces coelicolor hypothetical 24.7 kDa protein Sc1C3.1cC TR:O69860 (EMBL:AL023702) (238 aa) fasta scores: E(): 1.2e-22, 41.17% id in 187 aa NP_939748.1 Similar to Mycobacterium tuberculosis CDC1551 ribonuclease D, MT2755 TR:AAK47070 (EMBL:AE007105) (438 aa) fasta scores: E(): 5.1e-49, 38.14% id in 409 aa, and to Escherichia coli ribonuclease D Rnd or B1804 SW:RND_ECOLI (P09155) (375 aa) fasta scores: E(): 1.2e-10, 28.36% id in 342 aa NP_939749.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_939750.1 Similar to Mycobacterium tuberculosis hypothetical 43.2 kDa protein Rv2689c or MT2763 or MTCY05A6.10c TR:O07191 (EMBL:Z96072) (405 aa) fasta scores: E(): 3.4e-27, 40.39% id in 401 aa, and to Streptomyces coelicolor SC10A5.06 protein TR:O54099 (EMBL:AL021529) (458 aa) fasta scores: E(): 1e-20, 31.59% id in 440 aa NP_939751.1 Similar to Mycobacterium leprae U1764K ML1029 TR:Q49993 (EMBL:U15181) (273 aa) fasta scores: E(): 1e-24, 38.88% id in 234 aa, and to Mycobacterium tuberculosis hypothetical 27.2 kDa protein Rv2696c or MTCY05A6.17c TR:O07198 (EMBL:Z96072) (259 aa) fasta scores: E(): 1.5e-24, 37.34% id in 241 aa NP_939752.1 catalyzes the formation of dUMP from dUTP NP_939753.1 Similar to Mycobacterium tuberculosis hypothetical 17.6 kDa protein Rv2698 or MTCY05A6.19 TR:O07200 (EMBL:Z96072) (161 aa) fasta scores: E(): 1.9e-21, 45.28% id in 159 aa, and to Mycobacterium leprae U1764I ML12027 TR:Q49991 (EMBL:U15181) (157 aa) fasta scores: E(): 3e-19, 41.77% id in 158 aa NP_939754.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa NP_939755.1 Similar to Mycobacterium tuberculosis inositol-1-monophosphatase SuhB or Rv2701c or MT2775 or MTCY05A6.22c SW:SUHB_MYCTU (O07203) (290 aa) fasta scores: E(): 1e-38, 45% id in 280 aa, and to Escherichia coli inositol-1-monophosphatase SuhB or SsyA or B2533 SW:SUHB_ECOLI (P22783) (267 aa) fasta scores: E(): 3.2e-19, 37.22% id in 231 aa NP_939756.1 Similar to Mycobacterium tuberculosis polyphosphate glucokinase PpgK or Rv2702 or MT2776 or MTCY05A6.23 SW:PPGK_MYCTU (Q59568) (265 aa) fasta scores: E(): 1.5e-50, 57.91% id in 240 aa, and to Corynebacterium ammoniagenes polyphosphate glucokinase PpgK TR:Q9AGV8 (EMBL:AF326348) (277 aa) fasta scores: E(): 3.2e-59, 63.85% id in 249 aa NP_939758.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released NP_939760.1 Similar, but shorter in its N-terminal region, to Mycobacterium tuberculosis hypothetical 65.8 kDa protein Rv2917 or MT2985 or MTCY338.05 SW:YT17_MYCTU (Q10966) (602 aa) fasta scores: E(): 6.4e-116, 62.39% id in 569 aa, and to Mycobacterium leprae hypothetical 65.2 kDa protein ML1624 or MLCB250.18c SW:YT17_MYCLE (O33011) (596 aa) fasta scores: E(): 8.8e-113, 60.28% id in 569 aa NP_939761.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2781 TR:AAK47097 (EMBL:AE007107) (82 aa) fasta scores: E(): 1.4e-17, 65.78% id in 76 aa, and to Mycobacterium leprae U1764c ML1016 TR:Q49984 (EMBL:U15181) (107 aa) fasta scores: E(): 2.8e-16, 65.78% id in 76 aa NP_939763.1 Similar to Streptomyces coelicolor transferase SCH5.08c TR:Q9X911 (EMBL:AL035636) (505 aa) fasta scores: E(): 3.6e-46, 35.44% id in 522 aa NP_939764.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_939765.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase NP_939766.1 Almost identical to the previously sequenced Corynebacterium diphtheriae diphtheria toxin repressor DtxR SW:DTXR_CORDI (P33120) (226 aa) fasta scores: E(): 7.6e-81, 99.11% id in 226 aa, and similar to Corynebacterium equii iron dependent regulatory protein IdeR TR:Q9F7T3 (EMBL:AF277002) (230 aa) fasta scores: E(): 1.1e-43, 56.71% id in 231 aa NP_939767.1 Almost identical to previously sequenced Corynebacterium diphtheriae UDP-glucose 4-epimerase GalE SW:GALE_CORDI (P33119) (328 aa) fasta scores: E(): 1.6e-126, 99.39% id in 328 aa, and to Corynebacterium glutamicum UDP-glucose 4-epimerase GalE SW:GALE_CORGL (Q45291) (329 aa) fasta scores: E(): 5.1e-97, 75.22% id in 327 aa, and to Lactobacillus casei UDP-glucose 4-epimerase GalE SW:GALE_LACCA (O84903) (331 aa) fasta scores: E(): 3.1e-55, 48.89% id in 317 aa NP_939769.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2787 TR:AAK47103 (EMBL:AE007107) (324 aa) fasta scores: E(): 2.1e-45, 45.09% id in 306 aa, and to Streptomyces coelicolor conserved hypothetical protein SCI52.04 TR:Q9ADA5 (EMBL:AL590507) (333 aa) fasta scores: E(): 4.2e-12, 26.64% id in 304 aa NP_939770.1 Similar in its full length to Streptomyces coelicolor helicase SCG8A.06 TR:Q9KZJ3 (EMBL:AL353863) (854 aa) fasta scores: E(): 2.1e-184, 56.4% id in 828 aa, and to the C-terminal region of Schizosaccharomyces pombe helicase SPAC6F12.16c SW:YDVG_SCHPO (O14232) (1117 aa) fasta scores: E(): 1.5e-13, 27.64% id in 445 aa NP_939771.1 Similar to Mycobacterium tuberculosis AhpD protein or Rv2429 or MT2504 or MTCY428.17c SW:AHPD_MYCTU (Q57353) (177 aa) fasta scores: E(): 1.5e-38, 59.53% id in 173 aa, and to Streptomyces viridosporus hypothetical 18.8 kDa protein AhpX TR:Q9X5V1 (EMBL:AF127576) (174 aa) fasta scores: E(): 1.5e-28, 49.13% id in 173 aa NP_939772.1 Almost identical to previously sequenced Corynebacterium diphtheriae iron repressible polypeptide DirA TR:Q46025 (EMBL:U18620) (198 aa) fasta scores: E(): 8.8e-79, 98.99% id in 198 aa, and to Mycobacterium smegmatis alkyl hydroperoxide reductase C AhpC TR:Q57529 (EMBL:U43719) (195 aa) fasta scores: E(): 5.2e-52, 66.12% id in 186 aa NP_939773.1 Similar to Erwinia carotovora hydrogen peroxide-inducible genes activator OxyR SW:OXYR_ERWCA (P71318) (302 aa) fasta scores: E(): 1.6e-34, 37.5% id in 296 aa, and to Escherichia coli hydrogen peroxide-inducible genes activator OxyR or MomR or Mor or B3961 or Z5519 or ECS4890 SW:OXYR_ECOLI (P11721) (305 aa) fasta scores: E(): 7e-34, 37.8% id in 291 aa NP_939775.1 Similar to Escherichia coli ATP-dependent helicase HrpA or B1413 SW:HRPA_ECOLI (P43329) (1300 aa) fasta scores: E(): 1.7e-172, 46.92% id in 1315 aa, and to Vibrio cholerae ATP-dependent helicase HrpA VC1382 TR:Q9KS77 (EMBL:AE004217) (1309 aa) fasta scores: E(): 2.3e-171, 47.6% id in 1317 aa NP_939776.1 Similar to Mycobacterium tuberculosis hypothetical 17.2 kDa protein Rv2718c or MT2791 or MTCY05A6.39c SW:YR18_MYCTU (O07217) (154 aa) fasta scores: E(): 1.3e-35, 69.65% id in 145 aa, and to Bacillus subtilis hypothetical protein YtcG SW:YTCG_BACSU (Q45549) (152 aa) fasta scores: E(): 1.4e-21, 42% id in 150 aa NP_939778.1 Represses a number of genes involved in the response to DNA damage NP_939779.1 Similar to Streptomyces coelicolor DeoR-family transcriptional regulator SCE22.15c TR:Q9KYU7 (EMBL:AL355832) (253 aa) fasta scores: E(): 9.3e-31, 44.85% id in 243 aa, and to Escherichia coli galactitol utilization operon repressor GatR or B2087/B2090 SW:GATR_ECOLI (P36930) (259 aa) fasta scores: E(): 3.9e-20, 35.76% id in 260 aa. Note: Similar also to the downstream CDIP1429 267 aa, 41.634% identity in 257 aa overlap NP_939780.1 Similar to Corynebacterium glutamicum phosphoenolpyruvate:sugar phosphotransferase system enzyme I PtsI TR:AAK76445 (EMBL:AF392620) (565 aa) fasta scores: E(): 2.9e-159, 76.69% id in 562 aa, and to Xanthomonas campestris multiphosphoryl transfer protein FruB SW:PTF1_XANCP (P45597) (837 aa) fasta scores: E(): 1.4e-50, 37.2% id in 559 aa NP_939781.1 Similar to Spiroplasma citri transcriptional regulator FruR TR:Q9RMF6 (EMBL:AF202665) (233 aa) fasta scores: E(): 7.3e-17, 33.75% id in 237 aa, and to Escherichia coli galactitol utilization operon repressor GatR or B2087/B2090 SW:GATR_ECOLI (P36930) (259 aa) fasta scores: E(): 4e-13, 30% id in 240 aa. Note: Similar also to the upstream CDIP1427 258 aa, 41.634% identity in 257 aa overlap NP_939782.1 Similar to Rhodobacter capsulatus 1-phosphofructokinase FruK SW:K1PF_RHOCA (P23386) (316 aa) fasta scores: E(): 1.2e-05, 32.6% id in 322 aa, and to Escherichia coli 6-phosphofructokinase isozyme 2 PfkB or B1723 SW:K6P2_ECOLI (P06999) (309 aa) fasta scores: E(): 0.00069, 30.51% id in 308 aa NP_939783.1 Similar to Bacillus megaterium phosphocarrier protein HPr PtsH SW:PTHP_BACME (O69250) (88 aa) fasta scores: E(): 3e-06, 37.5% id in 80 aa, and to Bacillus subtilis phosphocarrier protein HPr PtsH SW:PTHP_BACSU (P08877) (87 aa) fasta scores: E(): 0.00032, 30.86% id in 81 aa NP_939784.1 Similar to Streptomyces coelicolor oxidoreductase SCE15.13c TR:Q9X888 (EMBL:AL049707) (367 aa) fasta scores: E(): 1.8e-106, 72.11% id in 355 aa, and to Photorhabdus luminescens alkanal monooxygenase alpha chain LuxA SW:LXA1_PHOLU (P19839) (360 aa) fasta scores: E(): 2.5e-06, 25.87% id in 228 aa NP_939785.1 Similar to Streptomyces coelicolor oxidoreductase SCE15.12c TR:Q9X887 (EMBL:AL049707) (222 aa) fasta scores: E(): 1.1e-26, 46.15% id in 221 aa, and to the middle region of Escherichia coli NAD SsuE or B0937 SW:SSUE_ECOLI (P80644) (191 aa) fasta scores: E(): 8.8e-09, 40.35% id in 114 aa NP_939786.1 Similar to Escherichia coli O157:H7 uracil transport protein PyrP TR:Q9KX94 (EMBL:AP000422) (442 aa) fasta scores: E(): 5e-46, 45.97% id in 422 aa, and to Escherichia coli uracil permease UraA or B2497 or Z3760 or ECS3359 SW:URAA_ECOLI (P33780) (429 aa) fasta scores: E(): 6.2e-25, 40.9% id in 396 aa NP_939787.1 Similar to Mycobacterium tuberculosis hypothetical 53.3 kDa protein HflX or Rv2725c or MTCY154.05c TR:O33230 (EMBL:Z98209) (495 aa) fasta scores: E(): 4.6e-102, 63.75% id in 469 aa, and to Escherichia coli GTP-binding protein HflX or B4173 SW:HFLX_ECOLI (P25519) (426 aa) fasta scores: E(): 3.1e-45, 40.62% id in 416 aa NP_939790.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_939791.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_939793.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 49.8 kDa protein MT2802 TR:AAK47120 (EMBL:AE007108) (450 aa) fasta scores: E(): 5.4e-66, 48.52% id in 441 aa NP_939795.1 Low similarity to Mycobacterium tuberculosis CDC1551 hypothetical 19.3 kDa protein MT2802.1 TR:AAK47121 (EMBL:AE007108) (180 aa) fasta scores: E(): 3.3e-07, 25.68% id in 183 aa NP_939796.1 Similar to Mycobacterium tuberculosis hypothetical 55.1 kDa protein Rv2733c or MT2803 or MTCY154.13c SW:YR33_MYCTU (O33238) (512 aa) fasta scores: E(): 2.7e-130, 67.67% id in 498 aa, and to Bacillus subtilis hypothetical 58.2 kDa protein in klb-cotE intergenic region YmcB SW:YMCB_BACSU (O31778) (509 aa) fasta scores: E(): 4.9e-65, 39.61% id in 462 aa NP_939797.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_939798.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_939799.1 Similar to Mycobacterium leprae hypothetical protein ML0986 TR:Q9CCC1 (EMBL:AL583920) (67 aa) fasta scores: E(): 7e-06, 39.68% id in 63 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2808 TR:AAK47129 (EMBL:AE007109) (68 aa) fasta scores: E(): 4.1e-05, 34.92% id in 63 aa NP_939800.1 Similar to Streptococcus pyogenes biotin synthase SPY0207 TR:Q9A1L4 (EMBL:AE006489) (179 aa) fasta scores: E(): 2e-15, 37.57% id in 173 aa, and to Rhizobium meliloti hypothetical transmembrane protein SMC00964 TR:CAC45460 (EMBL:AL591785) (187 aa) fasta scores: E(): 2.7e-14, 37.43% id in 179 aa NP_939801.1 Similar to Deinococcus radiodurans ABC transporter, ATP-binding protein DR2469 TR:Q9RRL9 (EMBL:AE002076) (226 aa) fasta scores: E(): 2.1e-33, 46.84% id in 222 aa, and to Rhizobium meliloti ATP-binding ABC transporter protein SMC00962 TR:CAC45462 (EMBL:AL591785) (226 aa) fasta scores: E(): 5e-27, 40.36% id in 218 aa NP_939802.1 Similar to Deinococcus radiodurans conserved hypothetical protein DR2468 TR:Q9RRM0 (EMBL:AE002076) (198 aa) fasta scores: E(): 7.8e-15, 36.18% id in 199 aa, and to Rhizobium meliloti hypothetical transmembrane protein SMC00963 TR:CAC45461 (EMBL:AL591785) (201 aa) fasta scores: E(): 2.5e-07, 29.38% id in 194 aa NP_939803.1 Similar in its full length to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SW:35KD_MYCTU (P31511) (270 aa) fasta scores: E(): 1.2e-51, 75.8% id in 248 aa, N-terminal region to Mycobacterium leprae B2235_C2_187 MLCB33.06c TR:Q49840 (EMBL:U00019) (167 aa) fasta scores: E(): 2.9e-27, 72.1% id in 147 aa, and C-terminal region to Mycobacterium leprae B2235_C3_214 MLCB33.05c TR:Q49845 (EMBL:U00019) (114 aa) fasta scores: E(): 3.4e-12, 58.18% id in 110 aa NP_939804.1 Similar to Mycobacterium tuberculosis CDC1551 DNA-binding protein, MT2816 TR:AAK47136 (EMBL:AE007109) (112 aa) fasta scores: E(): 1.2e-09, 56.16% id in 73 aa, and to Streptomyces coelicolor hypothetical 13.6 kDa protein SC7C7.10 TR:O86815 (EMBL:AL031031) (126 aa) fasta scores: E(): 1.1e-08, 49.39% id in 83 aa NP_939805.1 Similar to Streptomyces coelicolor hypothetical 18.5 kDa protein Sc7C7.09 TR:O86814 (EMBL:AL031031) (181 aa) fasta scores: E(): 1.7e-13, 36.87% id in 160 aa, and to the C-terminal region of Streptococcus pneumoniae competence-damage protein CinA or Exp10 or SP1941 SW:CINA_STRPN (P54184) (418 aa) fasta scores: E(): 4.3e-15, 47.86% id in 117 aa NP_939806.1 Similar to Bacillus subtilis CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA SW:PGSA_BACSU (P46322) (193 aa) fasta scores: E(): 1.6e-12, 40.55% id in 180 aa, and to Escherichia coli CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA or B1912 or Z3000 or ECS2650 SW:PGSA_ECOLI (P06978) (181 aa) fasta scores: E(): 1.7e-10, 35.91% id in 181 aa NP_939807.1 Similar to Agrobacterium tumefaciens StrC58 AGR_C_4802p TR:AAK88371 (EMBL:AE008178) (97 aa) fasta scores: E(): 2.2e-05, 33.67% id in 98 aa, and to Rhizobium loti MSR4226 protein TR:Q98EI5 (EMBL:AP003003) (98 aa) fasta scores: E(): 6e-05, 32.63% id in 95 aa NP_939808.1 Similar to Streptomyces coelicolor integral membrane protein SCM1.25c TR:Q9RD18 (EMBL:AL133422) (316 aa) fasta scores: E(): 3.1e-54, 48.93% id in 327 aa, and to Xylella fastidiosa export protein XF0406 TR:Q9PG96 (EMBL:AE003892) (319 aa) fasta scores: E(): 1.3e-39, 39.43% id in 317 aa NP_939809.1 Similar to Streptomyces coelicolor FtsK homolog SC7C7.05 TR:O86810 (EMBL:AL031031) (929 aa) fasta scores: E(): 2.1e-106, 50.17% id in 837 aa, and similar to C-terminal region of Escherichia coli cell division protein FtsK or B0890 SW:FTSK_ECOLI (P46889) (1329 aa) fasta scores: E(): 6.5e-34, 39.14% id in 700 aa NP_939810.1 Similar to Streptomyces coelicolor hypothetical 23.6 kDa protein SC4G6.14 TR:Q9S2U0 (EMBL:AL096884) (211 aa) fasta scores: E(): 1.4e-09, 31.86% id in 204 aa, and to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1929c or MTCY09F9.35 TR:P95285 (EMBL:Z84498) (214 aa) fasta scores: E(): 4.3e-07, 32.71% id in 217 aa NP_939811.1 Similar to Corynebacterium glutamicum hypothetical 77.6 kDa protein SW:YOR4_CORGL (P54122) (718 aa) fasta scores: E(): 1.9e-189, 79.21% id in 717 aa, and to Campylobacter jejuni hypothetical protein CJ1710c TR:Q9PLW8 (EMBL:AL139079) (664 aa) fasta scores: E(): 6.9e-65, 34.08% id in 625 aa NP_939812.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_939813.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor NP_939814.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_939815.1 Similar to Mycobacterium tuberculosis guanosine pentaphosphate synthetase/ polyribonucleotide nucleotidyltransferase GpsI or Rv2783c or MTV002.48C TR:O33325 (EMBL:AL008967) (752 aa) fasta scores: E(): 1.6e-187, 71.52% id in 755 aa, and to Bacillus subtilis polyribonucleotide nucleotidyltransferase PnpA or ComR SW:PNP_BACSU (P50849) (704 aa) fasta scores: E(): 4.6e-74, 45.5% id in 723 aa, and to Corynebacterium glutamicum polyribonucleotide nucleotidyltransferase CGL1975 SWALL:Q8NP50 (EMBL:AP005280) (753 aa) fasta scores: E(): 0, 82.04% id in 752 aa NP_939816.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_939817.1 Similar to Rhizobium meliloti nucleoside hydrolase SMC01105 TR:CAC41852 (EMBL:AL591783) (314 aa) fasta scores: E(): 2.3e-28, 33.96% id in 315 aa, and to Crithidia fasciculata inosine-uridine preferring nucleoside hydrolase IunH SW:IUNH_CRIFA (Q27546) (314 aa) fasta scores: E(): 4.6e-26, 33.33% id in 315 aa NP_939818.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_939819.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_939820.1 Similar to Streptomyces coelicolor hypothetical 24.5 kDa protein Sc5A7.23 TR:O88029 (EMBL:AL031107) (226 aa) fasta scores: E(): 6.2e-26, 45.77% id in 201 aa, and to Streptomyces verticillus phosphopantetheinyl transferase PptA TR:Q9F0Q6 (EMBL:AF210311) (246 aa) fasta scores: E(): 1.6e-24, 44.04% id in 193 aa NP_939821.1 Similar to Mycobacterium tuberculosis hypothetical 37.6 kDa protein Rv2795c or MTV002.60c TR:O33337 (EMBL:AL008967) (324 aa) fasta scores: E(): 1e-22, 46.79% id in 265 aa, and to Streptomyces coelicolor hypothetical 33.5 kDa protein SC5A7.22 TR:O88028 (EMBL:AL031107) (295 aa) fasta scores: E(): 1.1e-17, 41.63% id in 257 aa NP_939822.1 Similar to Mycobacterium tuberculosis hypothetical 44.8 kDa protein DinF or Rv2836c or MTCY16B7.06 TR:P71616 (EMBL:Z81331) (439 aa) fasta scores: E(): 1e-72, 50.59% id in 423 aa, and to Rhizobium loti DNA-damage-inducible protein MLR5680 TR:Q98B90 (EMBL:AP003007) (471 aa) fasta scores: E(): 1.9e-19, 30.07% id in 429 aa NP_939823.1 Similar to, although shorter in its N-terminal region than, Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv2837c or MTCY16B7.05 TR:P71615 (EMBL:Z81331) (336 aa) fasta scores: E(): 8.5e-29, 34.84% id in 287 aa, and to Clostridium acetobutylicum exopolyphosphatase CAC1804 TR:AAK79769 (EMBL:AE007689) (321 aa) fasta scores: E(): 1.9e-19, 33.19% id in 235 aa NP_939824.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_939825.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_939826.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2906 TR:AAK47232 (EMBL:AE007115) (99 aa) fasta scores: E(): 1.3e-06, 43.67% id in 87 aa, and to Rhizobium meliloti hypothetical protein SMC02913 TR:CAC41675 (EMBL:AL591783) (230 aa) fasta scores: E(): 0.00061, 32.14% id in 112 aa NP_939827.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_939828.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_939830.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_939831.1 Similar to Streptomyces coelicolor hypothetical 27.2 kDa protein SCC30.05 TR:Q9L016 (EMBL:AL352972) (260 aa) fasta scores: E(): 4.2e-19, 34.61% id in 260 aa, and to Neisseria meningitidis hypothetical protein NMA1114 TR:Q9JUV9 (EMBL:AL162755) (259 aa) fasta scores: E(): 6.9e-08, 27.23% id in 235 aa NP_939832.1 Similar to Propionibacterium freudenreichii shermanii uroporphyrinogen III methyltransferase CobA TR:Q51720 (EMBL:U13043) (257 aa) fasta scores: E(): 1.6e-37, 47.05% id in 238 aa, and to Bacillus megaterium uroporphyrinogen III methylase CysGA TR:O87699 (EMBL:AJ000758) (243 aa) fasta scores: E(): 4.5e-32, 44.58% id in 240 aa NP_939833.1 Similar to Bacillus halodurans BH3939 protein TR:Q9K5Z6 (EMBL:AP001520) (492 aa) fasta scores: E(): 6.3e-56, 41.8% id in 488 aa, and to Rhizobium meliloti hypothetical protein SMC00453 TR:CAC45554 (EMBL:AL591785) (490 aa) fasta scores: E(): 9.8e-55, 40.53% id in 491 aa NP_939834.1 Similar to Staphylococcus aureus (strain N315) hypothetical protein SA0410 or SAV0450 TR:BAB56612 (EMBL:AP003130) (400 aa) fasta scores: E(): 4.2e-50, 48.16% id in 326 aa, and to Pseudomonas denitrificans CobW protein SW:COBW_PSEDE (P29937) (353 aa) fasta scores: E(): 1.1e-19, 29.22% id in 349 aa NP_939835.1 Similar to Escherichia coli methylated-DNA--protein-cysteine methyltransferase Ogt or B1335 SW:OGT_ECOLI (P09168) (171 aa) fasta scores: E(): 8.7e-12, 32.7% id in 159 aa, and to Salmonella typhimurium methylated-DNA--protein-cysteine methyltransferase Ogt or STM1659 or STY1405 SW:OGT_SALTY (P37429) (171 aa) fasta scores: E(): 1e-10, 31.44% id in 159 aa NP_939836.2 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid NP_939837.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide NP_939838.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate NP_939839.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 38.2 kDa protein MT2921 TR:AAK47246 (EMBL:AE007116) (346 aa) fasta scores: E(): 5.6e-43, 40.95% id in 337 aa NP_939840.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide NP_939841.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation NP_939842.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential NP_939843.1 Similar to Mycobacterium tuberculosis penecillin binding protein Rv2864c or MTV003.10c TR:O33346 (EMBL:AL008883) (603 aa) fasta scores: E(): 1.9e-81, 42.81% id in 612 aa, and to Staphylococcus aureus beta-lactam-inducible penicillin-binding protein Pbp SW:PBP_STAAU (P07944) (670 aa) fasta scores: E(): 2.3e-07, 21.04% id in 632 aa NP_939844.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_939845.1 Similar to Mycobacterium leprae probable integral membrane protein ML1582 TR:Q9CBU4 (EMBL:AL583922) (404 aa) fasta scores: E(): 1.1e-60, 42.71% id in 405 aa NP_939846.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_939848.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_939849.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3867 TR:AAK48231 (EMBL:AE007181) (117 aa) fasta scores: E(): 1.1e-09, 47.25% id in 91 aa NP_939850.1 Similar to Mycobacterium tuberculosis phosphatidate cytidylyltransferase CdsA or Rv2881c or MT2948 or MTCY274.12c SW:CDSA_MYCTU (Q10807) (306 aa) fasta scores: E(): 2.4e-51, 51.73% id in 288 aa, and to Escherichia coli phosphatidate cytidylyltransferase CdsA or Cds or B0175 or Z0186 or ECS0177 SW:CDSA_ECOLI (P06466) (249 aa) fasta scores: E(): 1.9e-14, 35.35% id in 198 aa NP_939851.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_939852.1 Catalyzes the phosphorylation of UMP to UDP NP_939853.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_939854.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_939855.1 Similar to the N-terminal region of Mycobacterium tuberculosis hypothetical 25.8 kDa protein Rv2891 precursor or MT2958.2 or MTCY274.22 SW:YS91_MYCTU (Q10812) (249 aa) fasta scores: E(): 2.1e-14, 39.05% id in 169 aa NP_939856.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_939857.1 Similar to Mycobacterium tuberculosis hypothetical 40.1 kDa protein Rv2896c or MT2964 or MTCY274.27C SW:YS96_MYCTU (Q10817) (389 aa) fasta scores: E(): 3.5e-42, 42.21% id in 379 aa NP_939858.1 Similar to Mycobacterium tuberculosis hypothetical 52.9 kDa protein Rv2897c or MT2965 or MTCY274.28C SW:YS97_MYCTU (Q10818) (503 aa) fasta scores: E(): 8.8e-58, 45.63% id in 515 aa, and to Haemophilus influenzae competence protein ComM or HI1117 SW:COMM_HAEIN (P45049) (509 aa) fasta scores: E(): 3.5e-49, 36.59% id in 511 aa NP_939859.1 Similar to Streptomyces coelicolor hypothetical protein SC2E1.19 SW:YE19_STRCO (O69890) (130 aa) fasta scores: E(): 2.6e-05, 32.54% id in 126 aa NP_939860.1 Similar to Mycobacterium tuberculosis hypothetical 12.2 kDa protein Rv2901c or MT2969 or MTCY274.32c SW:YT01_MYCTU (Q10822) (101 aa) fasta scores: E(): 3.7e-31, 70.29% id in 101 aa, and to Streptomyces coelicolor hypothetical 12.3 kDa protein SC2E1.18 TR:O69889 (EMBL:AL023797) (102 aa) fasta scores: E(): 2.9e-27, 67% id in 100 aa NP_939861.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_939862.1 Similar to Mycobacterium tuberculosis probable signal peptidase I LepB or Rv2903c or MT2971 or MTCY274.34C SW:LEP_MYCTU (Q10789) (294 aa) fasta scores: E(): 3.3e-40, 44.18% id in 258 aa, and to Bacillus licheniformis signal peptidase I Sip SW:LEP_BACLI (P42668) (186 aa) fasta scores: E(): 5.7e-08, 30.56% id in 229 aa NP_939863.1 Similar to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 2.3e-44, 45.62% id in 263 aa. Identical to DIP0434, DIP1526, DIP1809 and DIP2123 NP_939864.1 Similar to Streptococcus pneumoniae hypothetical 20.7 kDa protein TR:Q9KK22 (EMBL:AF154034) (171 aa) fasta scores: E(): 1.3e-08, 33.75% id in 157 aa, and to Yersinia pestis insertion element IS1661 DNA-binding protein YPO4046 TR:CAC93502 (EMBL:AJ414160) (171 aa) fasta scores: E(): 0.00044, 25.45% id in 165 aa. Identical to DIP0435, DIP1525, DIP1808 and DIP2124 NP_939865.1 Similar to Corynebacterium diphtheriae secreted protein precursor TR:Q9XD85 (EMBL:AF109162) (339 aa) fasta scores: E(): 2.7e-34, 42.4% id in 250 aa NP_939867.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939868.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939869.1 Similar to Streptococcus pneumoniae hypothetical 20.7 kDa protein TR:Q9KK22 (EMBL:AF154034) (171 aa) fasta scores: E(): 1.3e-08, 33.75% id in 157 aa, and to Yersinia pestis insertion element ISs1661 DNA-binding protein YPO4091 TR:CAC93541 (EMBL:AJ414160) (171 aa) fasta scores: E(): 0.00044, 25.45% id in 165 aa. Identical to DIP0435, DIP1518, DIP1808 and DIP2124 NP_939870.1 Similar to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 2.3e-44, 45.62% id in 263 aa. Identical to DIP0434, DIP1517, DIP1809 and DIP2123 NP_939871.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_939872.1 Similar to Streptomyces coelicolor transcriptional accessory protein SC5F2A.26c TR:Q9X7P9 (EMBL:AL049587) (780 aa) fasta scores: E(): 8.5e-161, 59.94% id in 774 aa, and to Escherichia coli protein YhgF or B3407 SW:YHGF_ECOLI (P46837) (773 aa) fasta scores: E(): 7.3e-153, 57.44% id in 766 aa NP_939874.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_939875.1 Essential for efficient processing of 16S rRNA NP_939876.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_939877.1 Similar to Mycobacterium tuberculosis signal recognition particle protein Ffh or Rv2916c or MT2984 or MTCY338.04c SW:SR54_MYCTU (Q10963) (525 aa) fasta scores: E(): 2e-110, 66.6% id in 542 aa, and to Bacillus subtilis signal recognition particle protein Ffh SW:SR54_BACSU (P37105) (446 aa) fasta scores: E(): 3.2e-43, 51.52% id in 458 aa, and to Escherichia coli signal recognition particle protein Ffh or B2610 or Z3904 or ECS3473 SW:SR54_ECOLI (P07019) (453 aa) fasta scores: E(): 2.6e-38, 46.36% id in 468 aa NP_939878.1 Uridylylates and de-uridylylates the small trimeric protein Pii NP_939879.1 Similar to Corynebacterium glutamicum PII protein GlnB TR:Q9X705 (EMBL:AJ010319) (112 aa) fasta scores: E(): 3.4e-31, 73.21% id in 112 aa, and to Azospirillum brasilense nitrogen regulatory protein P-II GlnB SW:GLNB_AZOBR (P21193) (112 aa) fasta scores: E(): 5.2e-25, 57.14% id in 112 aa, and to Escherichia coli nitrogen regulatory protein P-II 1 GlnB or B2553 or Z3829 or ECS3419 or STY2808 SW:GLNB_ECOLI (P05826) (112 aa) fasta scores: E(): 2e-24, 59.82% id in 112 aa NP_939880.1 Similar to Salmonella enterica subsp. enterica serovar Typhi cell division protein FtsY TR:CAD08059 (EMBL:AL627281) (491 aa) fasta scores: E(): 5e-39, 35.58% id in 503 aa, and to Escherichia coli cell division protein FtsY or B3464 SW:FTSY_ECOLI (P10121) (497 aa) fasta scores: E(): 2.6e-38, 35.79% id in 500 aa NP_939881.1 No significant database matches. High content in alanine, leucine and valine amino acid residues Low G+C content (52.14%) NP_939882.1 Similar to Mycobacterium leprae chromosome partition protein Smc or ML1629 or MLCB250.01 SW:SMC_MYCLE (Q9CBT5) (1203 aa) fasta scores: E(): 1.4e-70, 46.09% id in 1191 aa, and to Bacillus subtilis chromosome partition protein Smc SW:SMC_BACSU (P51834) (1186 aa) fasta scores: E(): 2.1e-34, 28.92% id in 1217 aa. Note: Contains various possible colied-coil regions throughout the whole length of the CDS NP_939883.1 Similar to Mycobacterium tuberculosis acylphosphatase Rv2922.1c or MT2991 or MTCY338.11bc SW:ACYP_MYCTU (P56543) (93 aa) fasta scores: E(): 1.3e-14, 52.08% id in 96 aa, and to Escherichia coli acylphosphatase YccX or B0968 or Z1320 or ECS1052 SW:ACYP_ECOLI (P75877) (92 aa) fasta scores: E(): 1.2e-07, 43.82% id in 89 aa NP_939884.1 Similar to Staphylococcus aureus (strain N315) amino acid carrier protein AlsT or SA1190 or SAV1356 TR:BAB57518 (EMBL:AP003133) (486 aa) fasta scores: E(): 5.8e-84, 48.83% id in 473 aa, and to Bacillus subtilis amino acid carrier protein AlsT SW:ALST_BACSU (Q45068) (465 aa) fasta scores: E(): 1.3e-73, 46.18% id in 472 aa NP_939885.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_939886.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_939887.1 Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical 22.4 kDa protein Rrv2926c or MT2996 or MTCY338.15c SW:YT26_MYCTU (Q10972) (207 aa) fasta scores: E(): 9.5e-13, 30.46% id in 174 aa NP_939888.1 Similar to Mycobacterium tuberculosis hypothetical 27.0 kDa protein Rv2927c or MT2997 or MTCY338.16c SW:YT27_MYCTU (Q10973) (245 aa) fasta scores: E(): 9e-21, 47.89% id in 238 aa NP_939889.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer NP_939890.1 Similar to Bacillus halodurans glycerate kinase GlxK or BH0555 SW:GRK_BACHD (Q9Z9P2) (380 aa) fasta scores: E(): 1e-29, 35.14% id in 350 aa, and to Bacillus subtilis glycerate kinase GlxK or S14A SW:GRK_BACSU (P42100) (382 aa) fasta scores: E(): 7.1e-28, 32.4% id in 395 aa, and to Escherichia coli glycerate kinase 1 GlxK or GlxB5 or B0514 SW:GRK1_ECOLI (P77364) (381 aa) fasta scores: E(): 7.6e-25, 33.93% id in 333 aa NP_939893.1 Similar to Streptomyces coelicolor peptidase SCD17.07c TR:Q9RKM4 (EMBL:AL118515) (423 aa) fasta scores: E(): 6.6e-71, 45.3% id in 415 aa, and to Thermoplasma volcanium carboxypeptidase TVG0758219 TR:BAB59893 (EMBL:AP000993) (404 aa) fasta scores: E(): 2.1e-34, 34.03% id in 379 aa NP_939894.1 Similar to Escherichia coli maltodextrin phosphorylase MalP or B3417 SW:PHSM_ECOLI (P00490) (796 aa) fasta scores: E(): 5.5e-100, 44.48% id in 780 aa, and to Bacillus subtilis glycogen phosphorylase GlgP SW:PHSG_BACSU (P39123) (798 aa) fasta scores: E(): 1.2e-98, 45.43% id in 777 aa NP_939895.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_939896.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_939897.1 Similar to Mycobacterium tuberculosis indole-3-glycerol phosphate synthase TrpC or Rv1611 or MT1646 or MTCY01B2.03 SW:TRPC_MYCTU (O06129) (272 aa) fasta scores: E(): 1.4e-52, 55.59% id in 268 aa, and to Streptomyces coelicolor indole-3-glycerol phosphate synthase 1 TrpC1 or TrpC or SC4G6.08c SW:TRC1_STRCO (O68814) (269 aa) fasta scores: E(): 1.1e-44, 48.28% id in 263 aa NP_939898.1 Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1645 TR:AAK45914 (EMBL:AE007029) (235 aa) fasta scores: E(): 1e-08, 28.64% id in 206 aa NP_939899.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers NP_939900.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_939901.1 Similar to Corynebacterium glutamicum inositol monophosphate phosphatase ImpA TR:O52736 (EMBL:AF045998) (259 aa) fasta scores: E(): 3.2e-42, 50.42% id in 236 aa, and to Mycobacterium smegmatis inositol monophosphate phosphatase ImpA TR:O51845 (EMBL:AF005905) (276 aa) fasta scores: E(): 8e-34, 42.35% id in 255 aa NP_939902.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis NP_939903.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_939904.1 Similar to Streptomyces coelicolor transmembrane transport protein SC5G9.26c TR:Q9RL01 (EMBL:AL117385) (420 aa) fasta scores: E(): 8e-11, 28.37% id in 437 aa, and to Streptomyces lipmanii puromycin resistance protein Pur8 SW:PUR8_STRLP (P42670) (503 aa) fasta scores: E(): 2.4e-08, 24.39% id in 455 aa NP_939906.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_939907.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_939908.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_939910.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939911.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939913.1 Similar to Escherichia coli tetracycline repressor protein class D TetR SW:TER4_ECOLI (P09164) (217 aa) fasta scores: E(): 8.1e-09, 30.48% id in 187 aa, and to Pasteurella piscicida tetracycline repressor protein class H TetR SW:TER8_PASPI (P51562) (218 aa) fasta scores: E(): 8.1e-09, 30.48% id in 187 aa NP_939914.1 Similar to Mycobacterium tuberculosis glycogen operon protein GlgX homolog or Rv1564c or MT1615 or MTCY48.01 SW:GLGX_MYCTU (Q10767) (721 aa) fasta scores: E(): 5.5e-205, 69.12% id in 706 aa, and to Escherichia coli glycogen operon protein GlgX or GlyX or B3431 SW:GLGX_ECOLI (P15067) (657 aa) fasta scores: E(): 8.1e-87, 46.38% id in 664 aa NP_939915.1 Similar to Clostridium acetobutylicum DNA polymerase III epsilon subunit CAC0738 TR:AAK78714 (EMBL:AE007589) (306 aa) fasta scores: E(): 1.4e-14, 28.9% id in 339 aa, and to the exonuclease domain of Bacillus halodurans DNA polymerase III PolC-type PolC or BH2418 SW:DPO3_BACHD (Q9KA72) (1433 aa) fasta scores: E(): 2.7e-08, 28.62% id in 248 aa NP_939917.1 Similar to N-terminal region of Deinococcus radiodurans conserved hypothetical protein DRr1631 TR:Q9RTX1 (EMBL:AE002006) (394 aa) fasta scores: E(): 4.7e-12, 31.28% id in 211 aa NP_939918.1 Similar to Rhizobium loti MLR3853 protein TR:Q98FB3 (EMBL:AP003002) (131 aa) fasta scores: E(): 2.9e-09, 42.01% id in 119 aa, and to Escherichia coli heat shock protein 15 HslR or B3400 or Z4754 or ECS4242 SW:HSLR_ECOLI (P45802) (133 aa) fasta scores: E(): 2.7e-06, 32.54% id in 126 aa NP_939920.1 Similar to Bacillus subtilis hypothetical 24.8 kDa protein in degS-tagO intergenic region YvyE or YvhK SW:YVYE_BACSU (P32437) (217 aa) fasta scores: E(): 1.3e-24, 37.5% id in 208 aa NP_939921.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic NP_939922.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_939923.1 Similar to Streptomyces coelicolor integral membrane protein SCD20.10c TR:Q9F2W9 (EMBL:AL392148) (362 aa) fasta scores: E(): 2.4e-45, 45.54% id in 292 aa NP_939925.1 Similar to Mycobacterium leprae pseudouridine synthase RluC or ML1200 or MLCB458.15 TR:Q9X7E8 (EMBL:AL049478) (308 aa) fasta scores: E(): 1.2e-79, 68.62% id in 306 aa, and to Streptomyces coelicolor ribosomal large subunit pseudouridine synthase SC4A10.06c TR:Q9S2X8 (EMBL:AL109663) (314 aa) fasta scores: E(): 8.5e-75, 64.37% id in 306 aa NP_939926.1 Similar to Streptomyces coelicolor lipoprotein signal peptidase SC4A10.07c TR:Q9S2X7 (EMBL:AL109663) (204 aa) fasta scores: E(): 1e-20, 43.03% id in 165 aa, and to Bacillus subtilis lipoprotein signal peptidase LspA or Lps SW:LSPA_BACSU (Q45479) (154 aa) fasta scores: E(): 1.7e-11, 35.71% id in 154 aa NP_939928.1 Similar to Mycobacterium tuberculosis lipoprotein LppK precursor or Rv2116 or MT2176 or MTCY261.12 SW:LPPK_MYCTU (O33251) (189 aa) fasta scores: E(): 0.0014, 30.48% id in 187 aa NP_939929.1 Similar to Mycobacterium leprae probable L-asparaginase AnsA or ML1198 or MLCB458.13c SW:ASPG_MYCLE (Q9X7E6) (310 aa) fasta scores: E(): 4.7e-19, 37.65% id in 316 aa, and to Erwinia chrysanthemi L-asparaginase precursor AnsB or Asn SW:ASPG_ERWCH (P06608) (348 aa) fasta scores: E(): 3.4e-09, 29.51% id in 332 aa. Also similar to DIP0491 E(): 2e-48, 52.303% identity in 304 aa overlap NP_939930.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function NP_939931.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) NP_939932.1 Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three colied-coil regions (residues 84..131, 193..235, 248..273) NP_939933.1 Similar to Streptomyces coelicolor hypothetical 10.7 kDa protein SC4A10.11c TR:Q9S2X3 (EMBL:AL109663) (94 aa) fasta scores: E(): 2.6e-09, 34.78% id in 92 aa, and to Mycobacterium leprae possible membrane protein ML0921 TR:Q9CCE0 (EMBL:AL583920) (96 aa) fasta scores: E(): 6.7e-09, 41.57% id in 89 aa NP_939934.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_939935.1 Similar to Corynebacterium glutamicum Yak1 protein TR:Q9KX18 (EMBL:Y08964) (152 aa) fasta scores: E(): 1.1e-21, 52.9% id in 155 aa, and to Streptomyces coelicolor conserved hypothetical protein 2SCI34.02 TR:Q9EWX7 (EMBL:AL445403) (146 aa) fasta scores: E(): 9.1e-07, 31.88% id in 138 aa NP_939936.1 Similar to Corynebacterium glutamicum hypothetical 26.0 kDa protein in FtsZ 3'region SW:YFTZ_CORGL (P94338) (246 aa) fasta scores: E(): 6.5e-66, 68.72% id in 243 aa, and to Streptomyces griseus hypothetical 25.3 kDa protein in FtsZ 3'region SW:YFTZ_STRGR (P45496) (246 aa) fasta scores: E(): 7.4e-41, 50% id in 228 aa NP_939937.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_939938.1 Similar to Corynebacterium glutamicum cell division protein homolog FtsQ or DivB SW:FTSQ_CORGL (P94336) (222 aa) fasta scores: E(): 3.3e-30, 41.36% id in 220 aa, and to Mycobacterium tuberculosis cell division protein homolog FtsQ or Rv2151c or MT2210 or MTCY270.17 SW:FTSQ_MYCTU (O06226) (314 aa) fasta scores: E(): 4e-16, 32.4% id in 216 aa NP_939939.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_939940.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_939941.1 Similar to Corynebacterium glutamicum FtsW protein TR:Q9L4H4 (EMBL:AJ242646) (490 aa) fasta scores: E(): 9.6e-78, 48.85% id in 481 aa, and to Escherichia coli cell division protein FtsW or B0089 or Z0099 or ECS0093 SW:FTSW_ECOLI (P16457) (414 aa) fasta scores: E(): 1e-21, 32.53% id in 375 aa NP_939942.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_939943.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_939944.1 Similar to Mycobacterium tuberculosis UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-- D-alanyl-D- alanyl ligase MurF or Rv2157c or MT2216 or MTCY270.11 SW:MURF_MYCTU (O06220) (510 aa) fasta scores: E(): 2.3e-75, 49.7% id in 513 aa, and to Streptomyces toyocaensis probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-- D- alanyl-D-alanyl ligase MurF or MurX SW:MURF_STRTO (O33804) (443 aa) fasta scores: E(): 3.9e-30, 40.6% id in 495 aa NP_939945.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_939946.1 Similar to Corynebacterium glutamicum penicillin-binding protein FtsI TR:Q9FAD4 (EMBL:AB041009) (704 aa) fasta scores: E(): 3.1e-122, 59.38% id in 677 aa, and to Streptomyces coelicolor FtsI TR:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 2e-42, 32.24% id in 611 aa NP_939948.1 Similar to Mycobacterium tuberculosis hypothetical 37.2 kDa protein Rv2165c or MT2223 or MTCY270.03 SW:YL65_MYCTU (O06212) (344 aa) fasta scores: E(): 4.8e-62, 56.34% id in 323 aa NP_939949.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_939950.1 Similar to Mycobacterium tuberculosis hypothetical 14.6 kDa protein Rv2169c or MTV021.02c TR:O53503 (EMBL:AL021957) (134 aa) fasta scores: E(): 8.5e-11, 38.93% id in 131 aa NP_939952.1 Similar to Mycobacterium tuberculosis hypothetical 22.9 kDa protein Rv2170 or MTV021.03 TR:O53504 (EMBL:AL021957) (206 aa) fasta scores: E(): 3.4e-16, 35.14% id in 202 aa NP_939953.1 Similar to Streptomyces lividans 5,10-methylenetetrahydrofolate reductase MetF SW:METF_STRLI (O54235) (307 aa) fasta scores: E(): 4.1e-41, 41.58% id in 303 aa, and to Escherichia coli 5,10-methylenetetrahydrofolate reductase MetF or B3941 SW:METF_ECOLI (P00394) (296 aa) fasta scores: E(): 9.2e-15, 33.65% id in 309 aa NP_939954.1 Similar to Mycobacterium aurum geranylgeranyl pyrophosphate synthase GgpP TR:Q9K567 (EMBL:AJ133724) (371 aa) fasta scores: E(): 1.5e-36, 39.09% id in 353 aa, and to Sulfolobus acidocaldarius geranylgeranyl pyrophosphate synthetase Gds SW:GGPP_SULAC (P39464) (330 aa) fasta scores: E(): 3.1e-11, 28.49% id in 358 aa NP_939955.1 Similar to Mycobacterium tuberculosis membrane protein Rv2174 or MTV021.07 TR:O53508 (EMBL:AL021957) (516 aa) fasta scores: E(): 2.2e-56, 34.69% id in 464 aa NP_939956.1 Similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv2175c or MTV021.08c TR:O53509 (EMBL:AL021957) (146 aa) fasta scores: E(): 7.8e-08, 40.45% id in 131 aa NP_939957.1 Similar to Streptomyces coelicolor eukaryotic-type protein kinase PkaF TR:Q9ZNB3 (EMBL:AB019394) (629 aa) fasta scores: E(): 8.2e-37, 36.22% id in 646 aa NP_939958.1 Similar to Streptomyces coelicolor phospho-2-dehydro-3-deoxyheptonate aldolase AroH or SC6E10.09c SW:AROF_STRCO (P80574) (449 aa) fasta scores: E(): 2.4e-92, 55.6% id in 437 aa, and to Mycobacterium tuberculosis CDC1551 phospho-2-dehydro-3-deoxyheptonate aldolase, MT2234 TR:AAK46519 (EMBL:AE007070) (462 aa) fasta scores: E(): 2.9e-129, 67.53% id in 462 aa NP_939959.1 Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2234.1 TR:AAK46520 (EMBL:AE007070) (168 aa) fasta scores: E(): 1.1e-35, 59.35% id in 155 aa NP_939960.1 Similar to Corynebacterium glutamicum hypothetical 27.1 kDa protein TR:Q9KKE6 (EMBL:AF096280) (245 aa) fasta scores: E(): 1.9e-67, 67.91% id in 240 aa, and to Streptomyces coelicolor acyltransferase 2SCG1.03 TR:Q9FCD9 (EMBL:AL391014) (240 aa) fasta scores: E(): 1.3e-37, 46.63% id in 238 aa NP_939961.1 Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa NP_939962.1 Similar to Mycobacterium leprae hypothetical 41.1 kDa protein ML0886 or MLCB268.31c TR:O69579 (EMBL:AL022602) (384 aa) fasta scores: E(): 1.9e-64, 51.18% id in 381 aa, and to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT2243 TR:AAK46529 (EMBL:AE007070) (385 aa) fasta scores: E(): 8e-64, 50.65% id in 381 aa NP_939963.1 Similar to Mycobacterium leprae secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 1.7e-22, 36.2% id in 348 aa NP_939964.1 Similar to the C-terminal region of Mycobacterium leprae secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 6e-19, 40.35% id in 223 aa NP_939966.1 Similar to Corynebacterium glutamicum cytochrome B of BC1 complex CytB or QcrB TR:Q9AEL5 (EMBL:AJ306418) (539 aa) fasta scores: E(): 1.1e-173, 81.08% id in 534 aa, and to Streptomyces lividans ubiquinol-cytochrome C reductase cytochrome B subunit QcrB SW:QCRB_STRLI (Q9ZFB6) (549 aa) fasta scores: E(): 2.2e-88, 47.32% id in 486 aa NP_939967.1 Similar to Corynebacterium glutamicum iron-sulfur protein QcrA TR:Q9F482 (EMBL:AB047851) (392 aa) fasta scores: E(): 5.7e-128, 76.78% id in 392 aa, and to Mycobacterium tuberculosis ubiquinol-cytochrome C reductase iron-sulfur subunit QcrA or Rv2195 or MT2251 or MTCY190.06 SW:QCRA_MYCTU (Q10387) (429 aa) fasta scores: E(): 4.9e-37, 51.13% id in 395 aa NP_939968.1 Similar to Corynebacterium glutamicum cytochrome CC1 subunit QcrC TR:Q9F483 (EMBL:AB047851) (283 aa) fasta scores: E(): 1.9e-86, 81.36% id in 279 aa, and to Mycobacterium tuberculosis ubiquinol-cytochrome C reductase cytochrome C subunit QcrC or Rv2194 or MT2250 or MTCY190.05 SW:QCRC_MYCTU (Q10386) (280 aa) fasta scores: E(): 3.5e-29, 60.43% id in 278 aa NP_939969.1 Similar to Corynebacterium glutamicum cytochrome AA3 oxidase subunit III CtaE TR:Q9AEL8 (EMBL:AJ306418) (205 aa) fasta scores: E(): 9.9e-67, 81.95% id in 205 aa, and to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide III CtaE or Rv2193 or MT2249 or MTCY190.04 SW:COX3_MYCTU (Q10385) (203 aa) fasta scores: E(): 3.6e-47, 60% id in 205 aa NP_939970.1 Similar to Mycobacterium leprae membrane protein ML0876 TR:Q9CCF0 (EMBL:AL583920) (139 aa) fasta scores: E(): 6.6e-13, 34.93% id in 146 aa NP_939971.1 Similar to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide II precursor CtaC or Rv2200c or MT2256 or MTCY190.11c SW:COX2_MYCTU (Q10375) (363 aa) fasta scores: E(): 3.5e-59, 47.55% id in 347 aa, and to Bacillus subtilis cytochrome C oxidase polypeptide II precursor CtaC SW:COX2_BACSU (P24011) (356 aa) fasta scores: E(): 2.1e-07, 24.61% id in 321 aa NP_939972.1 Highly similar to Corynebacterium glutamicum LtsA TR:Q9LCB7 (EMBL:AB029550) (640 aa) fasta scores: E(): 0, 83.9% id in 640 aa, and to Bacillus subtilis asparagine synthetase [glutamine-hydrolyzing] 1 AsnB or Asn SW:ASNB_BACSU (P54420) (632 aa) fasta scores: E(): 2.8e-111, 49.76% id in 631 aa NP_939973.1 Similar to Corynebacterium glutamicum ORF1 TR:Q9LCB6 (EMBL:AB029550) (114 aa) fasta scores: E(): 3.2e-36, 84.21% id in 114 aa, and to Escherichia coli hypothetical protein YadR or B0156 or Z0167 or ECS0160 SW:YADR_ECOLI (P37026) (114 aa) fasta scores: E(): 7.2e-15, 44.66% id in 103 aa NP_939974.1 Similar to Streptomyces coelicolor integral membrane protein SC5F7.32 TR:Q9S2R7 (EMBL:AL096872) (251 aa) fasta scores: E(): 4.8e-10, 30.45% id in 220 aa NP_939975.1 Similar to Mycobacterium tuberculosis cobinamide kinase CobU or Rv0254c or MTV034.20 TR:O53676 (EMBL:AL021929) (174 aa) fasta scores: E(): 6.7e-21, 44.38% id in 178 aa, and to Escherichia coli, and bifunctional cobalamin biosynthesis protein CobU [includes: cobinamide kinase; cobinamide phosphate guanylyltransferase] or B1993 or Z3153 or ECS2788 SW:COBU_ECOLI (P46886) (181 aa) fasta scores: E(): 1.8e-13, 35.48% id in 186 aa NP_939976.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole NP_939977.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole NP_939978.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_939979.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_939980.1 Similar to Saccharopolyspora erythraea ORF1, 5' end; NADH-ferredoxin oxidoreductase (fragment) TR:Q54100 (EMBL:L38646) (93 aa) fasta scores: E(): 1.9e-08, 42.16% id in 83 aa NP_939981.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains NP_939982.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein NP_939983.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_939984.1 Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rvv2219 precursor or MT2276 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 2.4e-36, 42.8% id in 250 aa NP_939985.1 Similar to Streptomyces coelicolor integral membrane protein SC3H12.05c TR:Q9S2N9 (EMBL:AL355740) (155 aa) fasta scores: E(): 6.1e-16, 43.04% id in 151 aa NP_939986.1 Similar to Corynebacterium glutamicum glutamine synthetase I GlnA TR:O32354 (EMBL:Y13221) (477 aa) fasta scores: E(): 6.8e-157, 79.49% id in 478 aa, and to Streptomyces coelicolor glutamine synthetase GlnA or SC3H12.06 SW:GLNA_STRCO (P15106) (469 aa) fasta scores: E(): 3.6e-128, 66.31% id in 475 aa. Also similar to DIP1671, glnA2 (456 aa); fasta scores: E(): 5e-31, 32.353% identity in 476 aa overlap NP_939988.1 Similar to Caulobacter crescentus hypothetical protein CC3515 TR:Q9A2P1 (EMBL:AE006010) (188 aa) fasta scores: E(): 7.7e-06, 31.200% id in 125 aa NP_939991.1 Similar to Neisseria meningitidis hypothetical protein NMB0234 TR:Q9K1C8 (EMBL:AE002381) (179 aa) fasta scores: E(): 0.00039, 28.313% id in 166 aa NP_939992.1 Similar to Streptomyces coelicolor secreted protein SC2G5.19 TR:Q9Z5A4 (EMBL:AL035478) (1156 aa) fasta scores: E(): 7.4e-51, 32.373% id in 1041 aa NP_939994.1 Weak similarity to C-terminus of Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 4.3e-06, 26.943% id in 193 aa NP_939995.1 Weak similarity to C-terminus of Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.7e-07, 40.196% id in 102 aa NP_939996.1 Similar to Helicobacter pylori hypothetical 88.8 kDa protein HP1142 TR:O25761 (EMBL:AE000620) (759 aa) fasta scores: E(): 1.7e-53, 29.896% id in 766 aa, and to Staphylococcus aureus hypothetical 50.1 kDa protein TR:BAB47139 (EMBL:AB047239) (422 aa) fasta scores: E(): 1.4e-05, 24.340% id in 341 aa NP_940000.1 Similar to Agrobacterium tumefaciens AGR_C_1429p AGR_C_1429 TR:AAK86591 (EMBL:AE008011) (63 aa) fasta scores: E(): 0.0028, 45.283% id in 53 aa, and to Streptococcus pyogenes hypothetical protein SPY1261 TR:Q99ZE6 (EMBL:AE006565) (66 aa) fasta scores: E(): 0.0045, 37.931% id in 58 aa, and to Rhizobium meliloti hypothetical 10.1 kDa protein SMA2071 TR:AAK65789 (EMBL:AE007299) (96 aa) fasta scores: E(): 0.0053, 46.154% id in 52 aa, and to Staphylococcus aureus subspaureus N315. sigmaB-controlled gene product CsbD or SA1452 TR:Q99TM4 (EMBL:AP003134) (60 aa) fasta scores: E(): 0.0065, 38.983% id in 59 aa NP_940001.1 Similar to Neisseria meningitidis integral membrane protein NMA0370 TR:Q9JWH5 (EMBL:AL162753) (462 aa) fasta scores: E(): 8.6e-89, 59.488% id in 469 aa, and to Pasteurella multocida hypothetical protein PM0989 TR:Q9CM54 (EMBL:AE006138) (452 aa) fasta scores: E(): 3.3e-82, 52.402% id in 458 aa NP_940002.1 Similar to Streptomyces coelicolor GntR-family transcriptional regulator SCGD3.11c TR:Q9XA67 (EMBL:AL096822) (216 aa) fasta scores: E(): 3e-22, 35.122% id in 205 aa, and to Rhizobium meliloti GntR-family transcriptional regulator SMA0065 TR:AAK64690 (EMBL:AE007198) (230 aa) fasta scores: E(): 6.1e-11, 29.293% id in 198 aa NP_940003.1 Similar to Streptomyces viridifaciens valanimycin resistant protein VlmF TR:Q9LA76 (EMBL:AF148322) (402 aa) fasta scores: E(): 2.2e-10, 28.186% id in 408 aa, and to Pseudomonas aeruginosa probable MFS transporter PA5282 TR:Q9HTS2 (EMBL:AE004940) (389 aa) fasta scores: E(): 2.7e-06, 27.877% id in 391 aa NP_940004.1 Similar to Streptomyces coelicolor Mut-like protein 2SCG2.26c TR:Q9EX27 (EMBL:AL445963) (159 aa) fasta scores: E(): 1.3e-15, 46.7% id in 167 aa NP_940005.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_940006.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_940009.1 Almost identical to previously sequenced as Corynebacterium diphtheriae heme oxygenase HmuO SW:HMUO_CORDI (P71119) (215 aa) fasta scores: E(): 3.8e-78, 97.67% id in 215 aa NP_940010.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme NP_940011.1 Similar to Corynebacterium glutamicum glutamine synthetase II GlnA2 TR:Q9AEL4 (EMBL:AJ310086) (427 aa) fasta scores: E(): 4.4e-141, 78.4% id in 426 aa, and to Bacillus subtilis glutamine synthetase GlnA SW:GLNA_BACSU (P12425) (443 aa) fasta scores: E(): 1.3e-69, 44.62% id in 437 aa. Note: Also similar to DIP1644 (478 aa); fasta scores: E(): 9.9e-32; 32.353% identity in 476 aa overlap NP_940012.1 Similar to Mycobacterium tuberculosis hypothetical 56.3 kDa protein Rv2226 or MT2285 or MTCY427.07 SW:YM26_MYCTU (Q10510) (513 aa) fasta scores: E(): 2.6e-38, 34.64% id in 534 aa NP_940013.1 Low similarity to Streptomyces coelicolor hypothetical 10.4 kDa protein SCC75A.11c TR:Q9RKR3 (EMBL:AL133220) (92 aa) fasta scores: E(): 0.00053, 39.28% id in 56 aa NP_940014.1 Very low similarity to Homo sapiens galactokinase GalK1 or GalK SW:GAL1_HUMAN (P51570) blast scores: E(): 3e-05, score: 51 24% id NP_940016.1 Similar to Mycobacterium leprae hypothetical 39.8 kDa protein ML1637 or MLCB1243.38 TR:O69483 (EMBL:AL023635) (371 aa) fasta scores: E(): 1.8e-73, 54.61% id in 379 aa NP_940017.1 Low similarity to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2229c or MT2288 or MTCY427.10c SW:YM29_MYCTU (Q10513) (245 aa) fasta scores: E(): 1.9e-06, 23.75% id in 240 aa NP_940018.1 Similar to Mycobacterium leprae hypothetical 40.3 kDa protein ML1639 or MLCB1243.36 TR:O69481 (EMBL:AL023635) (385 aa) fasta scores: E(): 4.3e-74, 54.27% id in 374 aa NP_940019.1 Similar to Mycobacterium tuberculosis aminotransferase Rv2231c or MT2290 or MTCY427.12c SW:YM31_MYCTU (Q10503) (364 aa) fasta scores: E(): 1.7e-50, 45.67% id in 335 aa and to Salmonella typhimurium CobD TR:P97084 (EMBL:U90625) (364 aa) fasta scores: E(): 3.6e-18, 27.76% id in 335 aa NP_940020.1 Similar to Alcaligenes eutrophus phosphoglycolate phosphatase, chromosomal CbbZC SW:GPHC_ALCEU (P40852) (231 aa) fasta scores: E(): 3.5e-08, 30.85% id in 188 aa NP_940021.1 Similar to Streptomyces coelicolor low molecular weight protein-tyrosine-phosphatase PtpA or SCQ11.04c SW:PTPA_STRCO (P53433) (164 aa) fasta scores: E(): 1.3e-21, 47.43% id in 156 aa, and to Bos taurus low molecular weight phosphotyrosine protein phosphatase Acp1 SW:PPAC_BOVIN (P11064) (157 aa) fasta scores: E(): 9.2e-12, 35.55% id in 135 aa NP_940022.1 Similar to Mycobacterium tuberculosis hypothetical 29.8 kDa protein Rv2235 precursor or MT2294 or MTCY427.16 SW:YM35_MYCTU (Q10517) (271 aa) fasta scores: E(): 1.4e-34, 38.54% id in 275 aa NP_940023.1 Similar to Streptomyces coelicolor cobalamin biosynthesis protein CobD TR:Q9RJ21 (EMBL:AL132644) (327 aa) fasta scores: E(): 3.7e-39, 44.8% id in 308 aa, and to Rhodobacter capsulatus cobalamin biosynthesis protein CobD or BluD SW:COBD_RHOCA (Q52683) (314 aa) fasta scores: E(): 2.4e-23, 33.44% id in 311 aa NP_940024.1 Similar to Mycobacterium leprae hypothetical 15.2 kDa protein ML1649 or MLCB1243.26 TR:O69479 (EMBL:AL023635) (140 aa) fasta scores: E(): 4.1e-24, 56.55% id in 122 aa NP_940025.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC NP_940026.1 Similar to Streptomyces coelicolor secreted protein SCJ1.02c TR:Q9RJ12 (EMBL:AL109962) (195 aa) fasta scores: E(): 4.6e-25, 44.69% id in 179 aa NP_940027.1 Similar to Mycobacterium tuberculosis CDC1551 lipopolysaccharide biosynthesis protein WbpC, MT1616 TR:AAK45883 (EMBL:AE007027) (729 aa) fasta scores: E(): 8.2e-42, 34.25% id in 762 aa NP_940028.1 Similar to Mycobacterium leprae hypothetical 50.2 kDa protein ML1338 or MLC1351.25 TR:O05686 (EMBL:Z95117) (440 aa) fasta scores: E(): 1.8e-11, 29.77% id in 393 aa NP_940029.1 Similar to Mycobacterium tuberculosis CDC1551 hydrolase, alpha/beta hydrolase fold family MT3260 TR:AAK47599 (EMBL:AE007139) (323 aa) fasta scores: E(): 3.5e-10, 29.32% id in 324 aa NP_940030.1 Similar to Thermotoga maritima acyl carrier protein TM0662 TR:Q9WZD0 (EMBL:AE001739) (81 aa) fasta scores: E(): 0.0012, 32.05% id in 78 aa, and to Bacillus halodurans acyl carrier protein AcpA or BH2490 SW:ACP_BACHD (Q9KA04) (77 aa) fasta scores: E(): 0.0062, 32.87% id in 73 aa NP_940031.1 Similar to Streptomyces coelicolor conserved hypothetical protein SCE20.17c TR:Q9RDA8 (EMBL:AL136058) (259 aa) fasta scores: E(): 4.9e-62, 65.86% id in 249 aa, and to Escherichia coli NagD protein or B0675 or Z0822 or ECS0705 SW:NAGD_ECOLI (P15302) (250 aa) fasta scores: E(): 1e-37, 43.02% id in 251 aa NP_940033.1 Similar to Streptomyces coelicolor hypothetical 28.7 kDa protein SC4A7.08 TR:Q9RDQ4 (EMBL:AL133423) (273 aa) fasta scores: E(): 1.3e-49, 50.19% id in 259 aa NP_940034.1 Similar to Streptomyces coelicolor hypothetical protein SC2A11.15 SW:YU26_STRCO (O86576) (219 aa) fasta scores: E(): 8.3e-14, 32.68% id in 205 aa NP_940035.1 Similar to Mycobacterium tuberculosis CDC1551 hypothetical 10.3 kDa protein MT2407 TR:AAK46700 (EMBL:AE007081) (97 aa) fasta scores: E(): 2.2e-05, 46.42% id in 56 aa NP_940036.1 Similar to Corynebacterium glutamicum thiamine biosynthesis protein X ThiX SW:THIX_CORGL (P42461) (133 aa) fasta scores: E(): 2.5e-12, 38.09% id in 126 aa NP_940037.1 synthesizes RNA primers at the replication forks NP_940038.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_940039.1 Similar to Streptomyces aureofaciens guanyl-specific ribonuclease SA3 precursor RNAse3 SW:RNS3_STRAU (P30289) (141 aa) fasta scores: E(): 1.7e-10, 42.14% id in 140 aa NP_940041.1 dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate NP_940043.1 Similar to Mycobacterium tuberculosis hypothetical 70.0 kDa protein Rv2345 or MTCY98.14 TR:P95241 (EMBL:Z83860) (660 aa) fasta scores: E(): 1.6e-41, 30.4% id in 671 aa NP_940046.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_940047.1 Similar to Mycobacterium leprae ArsR-family transcriptional regulator ML0825 TR:Q9CCG5 (EMBL:AL583919) (140 aa) fasta scores: E(): 8.8e-08, 44.7% id in 85 aa, and to Sinorhizobium spAs4. ArsR TR:Q9RA93 (EMBL:AF178758) (115 aa) fasta scores: E(): 3.4e-05, 34.04% id in 94 aa NP_940048.1 Similar to Mycobacterium tuberculosis CDC1551 ferric uptake regulation protein MT2428 TR:AAK46722 (EMBL:AE007082) (130 aa) fasta scores: E(): 6.1e-24, 53.6% id in 125 aa, and to Escherichia coli ferric uptake regulation protein Fur or B0683 or Z0831 or ECS0714 SW:FUR_ECOLI (P06975) (148 aa) fasta scores: E(): 2.4e-10, 29.77% id in 131 aa NP_940049.1 Similar to Pseudomonas aeruginosa hypothetical protein PA3851 TR:Q9HXF5 (EMBL:AE004802) (250 aa) fasta scores: E(): 9.2e-22, 38.29% id in 235 aa, and to Pyrococcus abyssi hypothetical 40.7 kDa protein PAB1273 TR:Q9UY73 (EMBL:AJ248288) (364 aa) fasta scores: E(): 1.3e-12, 28.69% id in 345 aa NP_940050.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_940051.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_940052.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_940053.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal NP_940054.1 Similar to Mycobacterium tuberculosis hypothetical 47.2 kDa protein Rv2366c or MT2435 or MTCY27.14 SW:YN66_MYCTU (O05832) (435 aa) fasta scores: E(): 1.1e-67, 53.91% id in 434 aa NP_940055.1 Similar to Mycobacterium tuberculosis hypothetical 19.7 kDa protein Rv2367c or MT2436 or MTCY27.13 SW:YN67_MYCTU (O05831) (177 aa) fasta scores: E(): 4.7e-40, 69.33% id in 150 aa NP_940056.1 Similar to Mycobacterium tuberculosis PhoH-like protein Rv2368c or MT2437 or MTCY27.12 SW:PHOL_MYCTU (O05830) (352 aa) fasta scores: E(): 2.2e-66, 63.25% id in 313 aa, and to Bacillus subtilis PhoH-like protein PhoH SW:PHOL_BACSU (P46343) (319 aa) fasta scores: E(): 2.9e-52, 52.47% id in 303 aa NP_940057.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_940058.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_940059.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_940060.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_940062.1 No significant database matches. Note: Contains a potential sortase anchor site (LANTG) upstream of the C-terminal region transmembrane domain. Contains also a twin-arginine translocation (TAT) system recognition motif (RRVFAS) at the N-terminal region. Also similar to DIP0439, DIP0442, DIP2325 and DIP0443 NP_940063.1 Similar to Mycobacterium tuberculosis long-chain-fatty-acid-CoA ligase FadD15 or Rv2187 or MTV021.20 TR:O53521 (EMBL:AL021957) (600 aa) fasta scores: E(): 9.3e-80, 46.48% id in 611 aa, and to Streptomyces coelicolor long chain fatty acid CoA ligase SC6G10.04 TR:Q9X7Z0 (EMBL:AL049497) (598 aa) fasta scores: E(): 1.7e-78, 46.72% id in 610 aa NP_940064.1 Similar to Mycobacterium tuberculosis 4-alpha-glucanotransferase MalQ or Rv1781c or MT1831 or MTV049.03c SW:MALQ_MYCTU (O53932) (724 aa) fasta scores: E(): 7.8e-73, 45.87% id in 728 aa, and to Escherichia coli 4-alpha-glucanotransferase MalQ or MalA or B3416 SW:MALQ_ECOLI (P15977) (694 aa) fasta scores: E(): 1.2e-29, 28.48% id in 660 aa NP_940066.1 Similar to Escherichia coli peptidyl-dipeptidase Dcp or B1538 SW:DCP_ECOLI (P24171) (680 aa) fasta scores: E(): 6.5e-63, 38.52% id in 680 aa, and to Escherichia coli oligopeptidase A PrlC or OpdA or B3498 SW:OPDA_ECOLI (P27298) (680 aa) fasta scores: E(): 1.8e-37, 31.35% id in 689 aa NP_940067.1 Similar to Streptomyces coelicolor carboxylesterase SC5G9.30 TR:Q9RKZ7 (EMBL:AL117385) (518 aa) fasta scores: E(): 3.2e-14, 30.57% id in 363 aa, and to Bacillus subtilis para-nitrobenzyl esterase PnbA SW:PNBA_BACSU (P37967) (489 aa) fasta scores: E(): 7.3e-12, 28.22% id in 372 aa NP_940068.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate NP_940073.1 Similar to Amycolatopsis orientalis hypothetical 71.1 kDa protein PCZA363.2 CZA382.30 TR:O52818 (EMBL:AJ223999) (650 aa) fasta scores: E(): 1.8e-39, 30.58% id in 618 aa NP_940074.1 Similar to Corynebacterium glutamicum beta C-S lyase AecD TR:Q46061 (EMBL:M89931) (325 aa) fasta scores: E(): 3e-66, 53.93% id in 330 aa NP_940075.1 Similar to Corynebacterium glutamicum branched-chain amino acid transport system carrier protein BrnQ SW:BRNQ_CORGL (O06754) (426 aa) fasta scores: E(): 8.7e-50, 53.09% id in 420 aa, and to Escherichia coli branched-chain amino acid transport system II carrier protein BrnQ or B0401 or Z0499 or ECS0451 SW:BRNQ_ECOLI (P37011) (439 aa) fasta scores: E(): 2.4e-40, 33.17% id in 431 aa NP_940076.1 Similar to Agrobacterium tumefaciens StrC58 AGR_l_2217p TR:AAK89679 (EMBL:AE008310) (333 aa) fasta scores: E(): 5.1e-42, 45.79% id in 321 aa NP_940077.1 Similar to Corynebacterium glutamicum EctP protein (Transport of ectoine, glycine betaine, proline) TR:O86143 (EMBL:AJ001436) (615 aa) fasta scores: E(): 5.2e-181, 73.23% id in 609 aa, and to Bacillus subtilis glycine betaine transporter OpuD SW:OPUD_BACSU (P54417) (512 aa) fasta scores: E(): 2.4e-65, 38.35% id in 511 aa NP_940078.1 Similar to Rhizobium loti dipeptide-binding protein of ABC transporter MLR1186 TR:Q98L42 (EMBL:AP002996) (497 aa) fasta scores: E(): 8e-52, 34.96% id in 449 aa NP_940079.1 Similar to Rhizobium loti permease of oligopeptide ABC transporter MLR1187 TR:Q98L41 (EMBL:AP002996) (315 aa) fasta scores: E(): 1.3e-43, 42.2% id in 308 aa, and to Bacillus subtilis oligopeptide transport system permease AppB SW:APPB_BACSU (P42062) (317 aa) fasta scores: E(): 2e-35, 35.93% id in 320 aa NP_940080.1 Similar to Rhizobium loti permease of oligopeptide ABC transporter MLR1189 TR:Q98L40 (EMBL:AP002996) (289 aa) fasta scores: E(): 1.8e-49, 52.1% id in 261 aa, and to Escherichia coli dipeptide transport system permease DppC or B3542 or Z4959 or ECS4422 SW:DPPC_ECOLI (P37315) (300 aa) fasta scores: E(): 5e-36, 42.96% id in 270 aa NP_940081.1 Similar to Streptomyces coelicolor oligopeptide ABC transporter ATP-binding protein SCBAC1A6.35c TR:Q9ADF2 (EMBL:AL589708) (585 aa) fasta scores: E(): 1.2e-33, 44.29% id in 526 aa NP_940082.1 Similar to Streptomyces coelicolor prolyl aminopeptidase SCF43.16c TR:Q9RD72 (EMBL:AL136502) (433 aa) fasta scores: E(): 5e-44, 41.16% id in 396 aa, and to Aeromonas sobria proline iminopeptidase Pip or Pap SW:PIP_AERSO (P46547) (424 aa) fasta scores: E(): 8e-26, 40.25% id in 395 aa NP_940083.1 Similar to Xylella fastidiosa hypothetical protein XF1717 TR:Q9PCR1 (EMBL:AE003995) (266 aa) fasta scores: E(): 1.7e-28, 46.22% id in 225 aa NP_940084.1 Similar to Escherichia coli xylulose kinase XylB or B3564 SW:XYLB_ECOLI (P09099) (484 aa) fasta scores: E(): 6.8e-22, 30.57% id in 471 aa NP_940086.1 Similar to Lactococcus lactis NADH oxidase NoxC TR:Q9CHE6 (EMBL:AE006312) (547 aa) fasta scores: E(): 5.8e-81, 44.95% id in 545 aa, and to Enterococcus faecalis NADH oxidase Nox SW:NAOX_ENTFA (P37061) (446 aa) fasta scores: E(): 3.8e-30, 27.46% id in 437 aa NP_940087.1 Similar to Streptomyces coelicolor hypothetical 10.2 kDa protein SCF56.04c TR:Q9RD62 (EMBL:AL133424) (92 aa) fasta scores: E(): 4.6e-13, 52.22% id in 90 aa NP_940088.1 Similar to Vibrio cholerae glutathione-regulated potassium-efflux system protein KefB, VC0992 TR:Q9KTB1 (EMBL:AE004180) (528 aa) fasta scores: E(): 1.3e-37, 33.26% id in 514 aa NP_940090.1 Similar to Lactococcus lactis multidrug transporter YqiA TR:Q9CF47 (EMBL:AE006394) (476 aa) fasta scores: E(): 1.5e-87, 58.69% id in 460 aa, and to Streptomyces glaucescens tetracenomycin C resistance and export protein TcmA SW:TCMA_STRGA (P39886) (538 aa) fasta scores: E(): 3.8e-15, 24.88% id in 422 aa NP_940091.1 Similar to Crithidia fasciculata inosine-uridine preferring nucleoside hydrolase IunH SW:IUNH_CRIFA (Q27546) (314 aa) fasta scores: E(): 2.3e-73, 64.19% id in 310 aa NP_940092.1 Similar to Streptomyces coelicolor integral membrane protein SC4A2.12 TR:O86668 (EMBL:AL031182) (299 aa) fasta scores: E(): 9.2e-18, 34.31% id in 271 aa NP_940094.1 Similar to Neisseria meningitidis hypothetical protein NMA1791 TR:Q9JTG2 (EMBL:AL162757) (803 aa) fasta scores: E(): 1.8e-94, 40.58% id in 818 aa, and to Deinococcus radiodurans DNA modification methyltransferase-related protein DR2267 TR:Q9RS60 (EMBL:AE002059) (840 aa) fasta scores: E(): 1.8e-15, 25.93% id in 879 aa NP_940095.1 Similar to Mycobacterium tuberculosis CDC1551 Mrr restriction system protein MT2603 TR:AAK46913 (EMBL:AE007096) (306 aa) fasta scores: E(): 1.1e-06, 25.67% id in 261 aa, and to Escherichia coli restriction system protein Mrr or B4351 SW:MRR_ECOLI (P24202) (304 aa) fasta scores: E(): 0.015, 23.68% id in 266 aa. Note: In E.coli this ORF is involved in acceptance of foreign DNA which is modified, restricting both adenine and cytosime methylated DNA NP_940096.1 Doubtful CDS. No significant database matches NP_940097.1 Similar to Pasteurella multocida hypothetical protein PM1540 TR:Q9CKR6 (EMBL:AE006190) (309 aa) fasta scores: E(): 3.2e-26, 35.98% id in 239 aa, and to Staphylococcus aureus hypothetical protein SAV0801 TR:BAB56963 (EMBL:AP003360) (322 aa) fasta scores: E(): 1.6e-06, 22.13% id in 244 aa NP_940098.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_940100.1 Poor database matches. Weakly similar to Streptomyces coelicolor hypothetical protein SCI41.33c TR:O87592 (EMBL:AF086832) (196 aa) fasta scores: E(): 8.3, 24.27% id in 173 aa NP_940101.1 Similar to Corynebacterium glutamicum hypothetical protein CGL1238 SWALL:Q8NR26 (EMBL:AP005277) (383 aa) fasta scores: E(): 4.8e-30, 31.77% id in 384 aa, and to Bifidobacterium longum NCC2705 hypothetical protein BL0662 SWALL:AAN24484 (EMBL:AE014688) (368 aa) fasta scores: E(): 4.5e-20, 39.73% id in 380 aa NP_940102.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_940103.1 Poor database matches. C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv2405 TR:P71738 (EMBL:Z81368) (189 aa) fasta scores: E(): 1.9e-22, 43.7% id in 135 aa. Possible alternative translational start site NP_940104.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_940105.1 Similar to Escherichia coli threonine efflux protein RhtC SW:RHTC_ECOLI (P27846) (206 aa) fasta scores: E(): 2.7e-18, 30.43% id in 207 aa, and to Salmonella typhimurium LT2 threonine efflux protein RhtC TR:Q9L6N7 (EMBL:AF233324) (206 aa) fasta scores: E(): 1.7e-18, 30.88% id in 204 aa NP_940106.1 Similar to Streptomyces coelicolor ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa NP_940107.1 required for the assembly and function of the DNAX complex which are required fro the assembly of the beta subunit onto primed DNA NP_940108.1 Poor database matches. Weakly similar to Mycobacterium tuberculosis hypothetical protein Rv2414c TR:P71729 (EMBL:Z81368) (514 aa) fasta scores: E(): 7.8e-27, 33.81% id in 482 aa NP_940109.1 No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Bacillus halodurans late competence operon required for DNA binding and uptake BH1333 TR:Q9KD84 (EMBL:AP001511) (210 aa) fasta scores: E(): 0.00087, 40.55% id in 143 aa, and Streptomyces coelicolor DNA-binding protein SCC123.06c TR:Q9RDL8 (EMBL:AL136518) (355 aa) fasta scores: E(): 3e-06, 40.93% id in 193 aa NP_940110.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2417c TR:P71726 (EMBL:Z81368) (280 aa) fasta scores: E(): 1e-21, 34.92% id in 272 aa, and to Streptomyces coelicolor hypothetical protein SCC123.07c TR:Q9RDL7 (EMBL:AL136518) (281 aa) fasta scores: E(): 6e-21, 36.13% id in 274 aa NP_940111.1 Similar to Mycobacterium leprae possible phosphoglycerate mutase ML1452 TR:Q9CC00 (EMBL:AL583922) (224 aa) fasta scores: E(): 1.1e-34, 44.26% id in 244 aa, and to Mycobacterium tuberculosis hypothetical protein Rv2419c TR:P71724 (EMBL:Z81368) (223 aa) fasta scores: E(): 6.3e-34, 52.88% id in 191 aa NP_940112.1 Similar to Streptomyces coelicolor hypothetical protein SCC123.15c TR:Q9RDK9 (EMBL:AL136518) (148 aa) fasta scores: E(): 1.7e-21, 50.34% id in 145 aa, and to Mycobacterium tuberculosis hypothetical protein Rv2420c TR:O86327 (EMBL:Z81368) (126 aa) fasta scores: E(): 4.5e-20, 50.42% id in 117 aa NP_940113.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_940114.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_940115.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_940116.1 No significant database matches. Doubtful CDS NP_940117.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_940118.1 involved in the peptidyltransferase reaction during translation NP_940119.1 Similar to Escherichia coli 50S ribosomal protein L21 RplU SW:RL21_ECOLI (P02422) (103 aa) fasta scores: E(): 1.5e-10, 38.61% id in 101 aa, and to Mycobacterium leprae 50S ribosomal protein L21 ML1467 SW:RL21_MYCLE (Q9CBZ2) (103 aa) fasta scores: E(): 5.7e-23, 71% id in 100 aa NP_940120.1 C-terminus is similar to the N-terminal region of Escherichia coli ribonuclease E Rne SW:RNE_ECOLI (P21513) (1061 aa) fasta scores: E(): 5.5e-38, 33.08% id in 659 aa. Full length CDS is similar to Mycobacterium leprae possible ribonuclease ML1468 TR:Q9CBZ1 (EMBL:AL583922) (924 aa) fasta scores: E(): 1.1e-107, 47.24% id in 853 aa NP_940121.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_940122.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2446c TR:O53173 (EMBL:AL021246) (123 aa) fasta scores: E(): 1.5e-07, 31.35% id in 118 aa, and to Mycobacterium leprae conserved membrane protein ML1470 TR:Q9CBY9 (EMBL:AL583922) (123 aa) fasta scores: E(): 4.9e-07, 30.46% id in 128 aa NP_940123.1 Similar to Mycobacterium tuberculosis folylpolyglutamate synthase Rv2447c TR:O53174 (EMBL:AL021246) (487 aa) fasta scores: E(): 1.2e-100, 57.46% id in 496 aa, and to Mycobacterium leprae folylpolyglutamate synthase ML1471 TR:Q9CBY8 (EMBL:AL583922) (485 aa) fasta scores: E(): 3.8e-96, 56.17% id in 470 aa NP_940124.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_940125.1 catalyzes the oxidation of malate to oxaloacetate NP_940126.1 Similar to Rhizobium meliloti transcription regulator protein SMC04134 TR:CAC41505 (EMBL:AL591782) (225 aa) fasta scores: E(): 3.4e-17, 30.8% id in 198 aa, and to Caulobacter crescentus TetR family transcriptional regulator CC2608 TR:Q9A556 (EMBL:AE005928) (230 aa) fasta scores: E(): 4e-13, 31.7% id in 205 aa NP_940127.1 binds and unfolds substrates as part of the ClpXP protease NP_940128.1 N-terminal region is similar to Streptomyces griseus para-aminobenzoate synthase Pab SW:PABS_STRGR (P32483) (723 aa) fasta scores: E(): 1.8e-48, 39.11% id in 698 aa, and to Streptomyces pristinaespiralis p-aminobenzoate synthase PapA TR:P72539 (EMBL:U60417) (719 aa) fasta scores: E(): 6.1e-43, 35.83% id in 734 aa NP_940129.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_940130.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_940131.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_940132.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_940133.1 Poor database matches. Similar to the C-terminal region of Streptomyces coelicolor secreted protein SC1C2.11 TR:O86512 (EMBL:AL031124) (450 aa) fasta scores: E(): 0.47, 27.13% id in 269 aa NP_940134.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_940135.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2466c TR:O53193 (EMBL:AL021246) (207 aa) fasta scores: E(): 2.5e-43, 57.63% id in 203 aa, and to Mycobacterium leprae hypothetical protein ML1485 TR:Q9CBY0 (EMBL:AL583922) (207 aa) fasta scores: E(): 1.7e-40, 55.94% id in 202 aa NP_940136.1 Similar to Streptomyces lividans aminopeptidase N PepN SW:AMPN_STRLI (Q11010) (857 aa) fasta scores: E(): 1.2e-88, 45.27% id in 888 aa, and to Mycobacterium tuberculosis aminopeptidase Rv2467 TR:O53194 (EMBL:AL021246) (861 aa) fasta scores: E(): 1.9e-132, 51.97% id in 885 aa. CDS appears to be extended at the N-terminus in comparison to orthologues. Possible alternative translational start site, although current start has better RBS and extented region contains Pfam hit NP_940137.1 C-terminus is similar to thye C-terminal region of Streptomyces coelicolor hypothetical protein SCF43A.26C TR:Q9XA89 (EMBL:AL096837) (333 aa) fasta scores: E(): 1.4e-38, 41.75% id in 297 aa. Similar to an internal region of Streptomyces coelicolor membrane protein SC8E4A.26 TR:Q9L1X9 (EMBL:AL138662) (408 aa) fasta scores: E(): 2.7e-28, 38.41% id in 302 aa NP_940138.1 Similar to Mycobacterium tuberculosis hemoglobin-like protein Rv2470 TR:O53197 (EMBL:AL021246) (128 aa) fasta scores: E(): 6.5e-24, 51.61% id in 124 aa, and to Mycobacterium leprae hemoglobin-like protein ML1253 TR:Q9CC59 (EMBL:AL583921) (128 aa) fasta scores: E(): 5.9e-23, 50.8% id in 124 aa NP_940139.1 Limited database matches. Similar to Mycobacterium tuberculosis hypothetical protein Rv2474c TR:O53201 (EMBL:AL021246) (217 aa) fasta scores: E(): 2.2e-14, 39.59% id in 197 aa NP_940140.1 Similar to Halobacterium sp hypothetical protein VNG1407C TR:Q9HPZ1 (EMBL:AE005058) (132 aa) fasta scores: E(): 2.8e-09, 37.06% id in 116 aa, and to Pseudomonas aeruginosa hypothetical protein PA2801 TR:Q9I042 (EMBL:AE004707) (134 aa) fasta scores: E(): 4e-07, 35.38% id in 130 aa NP_940141.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence NP_940142.1 Similar to Mycobacterium tuberculosis single-strand binding protein Ssb SW:SSB_MYCTU (P71711) (164 aa) fasta scores: E(): 0.00073, 29.11% id in 158 aa, and to Mycobacterium smegmatis single-stranded DNA-binding protein TR:Q9AFI5 (EMBL:AF349434) (165 aa) fasta scores: E(): 0.00024, 27.95% id in 161 aa NP_940143.1 Similar to Mycobacterium leprae hypothetical protein ML1998 SW:Y102_MYCLE (P53525) (659 aa) fasta scores: E(): 2e-44, 31.72% id in 665 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0102 SW:Y102_MYCTU (Q10897) (661 aa) fasta scores: E(): 2.2e-44, 30.76% id in 650 aa NP_940144.1 Similar to Escherichia coli carbon starvation protein A CstA SW:CSTA_ECOLI (P15078) (701 aa) fasta scores: E(): 2.3e-129, 53.01% id in 696 aa, and to Mycobacterium tuberculosis carbon starvation protein A homologue Rv3063 SW:CSTA_MYCTU (P95095) (758 aa) fasta scores: E(): 5.9e-175, 61.47% id in 719 aa. CDS contains an extended N-terminus in comparison to the E. coli orthologue NP_940145.1 Similar to Pseudomonas aeruginosa hypothetical protein PA4605 TR:Q9HVI4 (EMBL:AE004874) (67 aa) fasta scores: E(): 0.032, 29.57% id in 71 aa, and to Campylobacter jejuni hypothetical protein Cj0916c TR:Q9PP17 (EMBL:AL139076) (65 aa) fasta scores: E(): 0.052, 34.61% id in 52 aa NP_940146.1 Similar to Streptococcus pneumoniae hypothetical 20.7 kDa protein TR:Q9KK22 (EMBL:AF154034) (171 aa) fasta scores: E(): 1.3e-08, 33.75% id in 157 aa and to Yersinia pestis insertion element IS1661 DNA-binding protein YPO3492 TR:CAC92721 (EMBL:AJ414157) (171 aa) fasta scores: E(): 0.00044, 25.45% id in 165 aa. Identical to DIP0435, DIP1518, DIP1525 and DIP2124 NP_940147.1 Similar to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 2.5e-43, 44.86% id in 263 aa. Identical to DIP0434, DIP1517, DIP1526 and DIP2123 NP_940148.1 Similar to Streptomyces spectabilis export protein SpcT TR:Q9L629 (EMBL:AF244574) (432 aa) fasta scores: E(): 3.1e-05, 28.46% id in 411 aa, and to Mycobacterium tuberculosis membrane protein Rv0246 TR:O53668 (EMBL:AL021929) (436 aa) fasta scores: E(): 5.4e-06, 20.94% id in 401 aa NP_940149.1 Similar to Rhizobium loti dehydrogenase; zinc-binding alcohol dehydrogenase; NADPH quinone oxidoreductase; oxidoreductase MLR3212 TR:Q98GR0 (EMBL:AP003001) (329 aa) fasta scores: E(): 4.7e-52, 47.67% id in 323 aa, and to Pseudomonas aeruginosa probable oxidoreductase PA1833 TR:Q9I2R2 (EMBL:AE004609) (330 aa) fasta scores: E(): 5.9e-45, 43.82% id in 324 aa NP_940150.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2509 TR:O06172 (EMBL:Z95556) (268 aa) fasta scores: E(): 1.3e-46, 52.25% id in 266 aa, and to Mycobacterium leprae dehydrogenase MLCl383.36c TR:O07709 (EMBL:Z97179) (268 aa) fasta scores: E(): 1.8e-44, 50.56% id in 265 aa NP_940151.1 3'-5' exoribonuclease specific for small oligoribonuclotides NP_940152.1 Similar to Corynebacterium glutamicum dihydrodipicolinate synthase DapA SW:DAPA_CORGL (P19808) (301 aa) fasta scores: E(): 7.7e-14, 29.25% id in 270 aa, and to Streptomyces coelicolor dihydrodipicolinate synthase SC9A10.08 SW:DAPA_STRCO (O86841) (299 aa) fasta scores: E(): 2.5e-13, 27.94% id in 272 aa NP_940153.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2518c TR:O53223 (EMBL:AL021185) (408 aa) fasta scores: E(): 6.9e-67, 53.02% id in 347 aa, and to Mycobacterium leprae secreted protein ML0426 TR:Q9CCU5 (EMBL:AL583918) (404 aa) fasta scores: E(): 5.2e-63, 49.28% id in 349 aa NP_940155.1 Weakly similar to Bacillus halodurans hypothetical protein Bh3463 TR:Q9K7A5 (EMBL:AP001518) (79 aa) fasta scores: E(): 2.9, 27.778% id in 72 aa NP_940159.1 Questionable CDS; no significant database matches NP_940161.1 Similar to bacteriophage phi-C31 hypothetical protein orf 7 TR:Q38028 (EMBL:X76288) (121 aa) fasta scores: E(): 0.0011, 40.385% id in 52 aa, and to Deinococcus radiodurans conserved hypothetical protein DR2409 TR:Q9RRS6 (EMBL:AE002071) (186 aa) fasta scores: E(): 0.0026, 39.683% id in 63 aa, and to Mycobacterium tuberculosis CDC1551 HNH endonuclease MT2545 TR:AAK46845 (EMBL:AE007091) (222 aa) fasta scores: E(): 0.049, 36.986% id in 73 aa NP_940162.1 Similar to Mycobacteriophage TM4 terminase gp4 TR:Q9ZX73 (EMBL:AF068845) (474 aa) fasta scores: E(): 2.6e-13, 24.364% id in 472 aa, and to Bacteriophage HK97 terminase large subunit 2 TR:Q9MCT1 (EMBL:AF069529) (504 aa) fasta scores: E(): 0.019, 23.741% id in 278 aa NP_940164.1 Some similarity to Clostridium perfringens plasmid pCP13 hypothetical 28.2 kDa protein pcp29 TR:BAB62467 (EMBL:AP003515) (252 aa) fasta scores: E(): 1.4e-05, 27.513% id in 189 aa NP_940166.1 Similar to Mycobacterium tuberculosis hypothetical 18.5 kDa protein Rv1577c or MTCY336.27 TR:O06613 (EMBL:Z95586) (170 aa) fasta scores: E(): 4.4e-06, 34.507% id in 142 aa, and to Mycobacterium tuberculosis hypothetical 19.3 kDa protein Rv2651c or MTCY441.20c TR:P71948 (EMBL:Z80225) (177 aa) fasta scores: E(): 4.5e-06, 35.664% id in 143 aa NP_940169.1 Similar to Bifidobacterium longum NCC2705 hypothetical protein BL0379 SWALL:AAN24215 (EMBL:AE014655) (140 aa) fasta scores: E(): 1.7e-05, 34.14% id in 123 aa NP_940170.1 Similar to Bacteriophage phi-C31 gp40 40 TR:Q9ZXA7 (EMBL:AJ006589) (143 aa) fasta scores: E(): 1.3e-05, 25.362% id in 138 aa NP_940171.1 Similar to Bacteriophage Mu hypothetical protein gp14 14 or e15 SW:VG14_BPMU (Q38492) (100 aa) fasta scores: E(): 0.86, 32.955% id in 88 aa NP_940172.1 Similar to Bacteriophage r1t ORF40 TR:Q38126 (EMBL:U38906) (213 aa) fasta scores: E(): 0.019, 25.904% id in 166 aa, and to Escherichia coli O157:H7 tail length tape measure protein precursor ECS2949 TR:BAB36372 (EMBL:AP002560) (881 aa) fasta scores: E(): 0.025, 27.698% id in 278 aa NP_940174.1 Contains collagen-like Pro/Gly repeat; Similar to Gallus gallus collagen alpha 1 Col3A1 SW:CA13_CHICK (P12105) (1262 aa) fasta scores: E(): 3.8e-13, 48.023% id in 177 aa NP_940175.1 Similar to Mycobacterium tuberculosis CDC1551 phage integrase MT2724 TR:AAK47038 (EMBL:AE007103) (332 aa) fasta scores: E(): 1.9e-29, 39.615% id in 260 aa, and to Bacillus subtilis probable integrase/recombinase RipX ripX SW:RIPX_BACSU (P46352) (296 aa) fasta scores: E(): 0.00033, 30.435% id in 230 aa NP_940177.1 Poor database matches. C-terminus is similar to the C-terminal regions of Streptomyces coelicolor nicotinamidase SCE19A.18 TR:Q9S2G3 (EMBL:AL096852) (195 aa) fasta scores: E(): 6.4e-06, 33.33% id in 105 aa, and Mycobacterium avium pyrazinamidase/nicotinamidase PncA TR:P94914 (EMBL:U80820) (187 aa) fasta scores: E(): 2.8e-05, 36% id in 125 aa NP_940178.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3592 TR:O06156 (EMBL:Z95555) (105 aa) fasta scores: E(): 1.5e-21, 58.16% id in 98 aa, and to Mycobacterium leprae hypothetical protein ML1922 TR:Q9CBI8 (EMBL:AL583923) (105 aa) fasta scores: E(): 5.5e-19, 53.46% id in 101 aa NP_940179.1 Poor database matches. Similar to Mycobacterium tuberculosis hypothetical protein Rv2520c TR:O53225 (EMBL:AL021185) (75 aa) fasta scores: E(): 2.7e-06, 45.33% id in 75 aa NP_940180.1 Similar to Escherichia coli bacterioferritin comigratory protein Bcp SW:BCP_ECOLI (P23480) (156 aa) fasta scores: E(): 7e-23, 46.8% id in 141 aa, and to Mycobacterium tuberculosis bacterioferritin comigratory protein Rv2521 TR:O53226 (EMBL:AL021185) (157 aa) fasta scores: E(): 3.5e-37, 62.17% id in 156 aa NP_940181.1 Similar to Rhizobium loti transcriptional regulator MLL3939 TR:Q98F48 (EMBL:AP003003) (209 aa) fasta scores: E(): 4.6e-12, 33.65% id in 208 aa, and to Pseudomonas aeruginosa probable transcriptional regulator PA1403 TR:Q9I3U1 (EMBL:AE004569) (210 aa) fasta scores: E(): 2e-05, 27.57% id in 214 aa NP_940182.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_940183.1 Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa NP_940185.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1343c SW:YD43_MYCTU (Q11013) (126 aa) fasta scores: E(): 6.9e-12, 47.61% id in 84 aa, and to Mycobacterium leprae hypothetical protein ML1177 SW:YD43_MYCLE (P54134) (126 aa) fasta scores: E(): 1.5e-11, 46.42% id in 84 aa NP_940186.1 Similar to Mycobacterium leprae hypothetical protein ML1176 (P54133) (119 aa) fasta scores: E(): 3.7e-09, 39.28% id in 112 aa, and to Mycobacterium tuberculosis hypothetical protein Rv1342c SW:YD42_MYCTU (Q11012) (120 aa) fasta scores: E(): 1.5e-08, 37.16% id in 113 aa NP_940187.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_940188.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_940189.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1339 SW:YD39_MYCTU (Q10648) (273 aa) fasta scores: E(): 5.5e-46, 46.18% id in 249 aa, and to Mycobacterium leprae hypothetical protein ML1173 SW:YD39_MYCLE (P50474) (284 aa) fasta scores: E(): 6.6e-46, 46.18% id in 249 aa NP_940190.1 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_940191.1 Similar to Synechocystis sp. hypothetical protein SLR1461 TR:P74553 (EMBL:D90916) (198 aa) fasta scores: E(): 3e-21, 38.95% id in 172 aa, and to Bacillus halodurans hypothetical protein BH0517 TR:Q9KFG2 (EMBL:AP001508) (248 aa) fasta scores: E(): 3.1e-05, 29.1% id in 189 aa NP_940192.1 Similar to Mycobacterium leprae hypothetical protein ML1167 SW:YD33_MYCLE (P53425) (362 aa) fasta scores: E(): 4.2e-24, 48.07% id in 337 aa, and to Streptomyces coelicolor hypothetical protein SCE22.10 TR:Q9KYV2 (EMBL:AL355832) (348 aa) fasta scores: E(): 4.6e-24, 47.38% id in 325 aa NP_940193.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1332 SW:YD32_MYCTU (Q10643) (218 aa) fasta scores: E(): 1.3e-10, 35.53% id in 197 aa, and to Mycobacterium leprae hypothetical protein ML1166 SW:YD32_MYCLE (P53424) (217 aa) fasta scores: E(): 2.1e-08, 33.5% id in 200 aa. CDS is contains fewer residues at the N-terminus in comparison to the Mycobacterium proteins NP_940194.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA NP_940195.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_940196.1 Similar to Escherichia coli probable ATP-dependent helicase DinG SW:DING_ECOLI (P27296) (716 aa) fasta scores: E(): 5.6e-15, 27.57% id in 689 aa, and to Mycobacterium tuberculosis probable ATP-dependent helicase DinG homologue Rv1329c SW:DING_MYCTU (Q10640) (664 aa) fasta scores: E(): 2.2e-131, 55.84% id in 659 aa NP_940197.1 Similar to Streptomyces coelicolor acetyltransferase SCC46.14 TR:Q9L1I8 (EMBL:AL139164) (202 aa) fasta scores: E(): 1.3e-08, 28.09% id in 178 aa, and to Deinococcus radiodurans acetyltransferase DR1800 TR:Q9RTG4 (EMBL:AE002021) (179 aa) fasta scores: E(): 8.9e-08, 29.76% id in 168 aa NP_940198.1 No significant database matches to the full length CDS. C-terminus is similar to an internal region of Mycobacterium tuberculosis hypothetical protein Rv2100 SW:YL00_MYCTU (Q10709) (550 aa) fasta scores: E(): 9.8e-09, 35.15% id in 128 aa NP_940199.1 Poor database matches. Similar to Streptomyces coelicolor hypothetical protein SC1B5.06c TR:O69834 (EMBL:AL023517) (249 aa) fasta scores: E(): 9e-23, 41.42% id in 210 aa. C-terminal region is similar to Pyrococcus horikoshii hypothetical protein PH1539 SW:YF39_PYRHO (O74017) (121 aa) fasta scores: E(): 0.0025, 36.84% id in 95 aa NP_940200.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa NP_940201.1 Similar to Bacillus firmus cytochrome C oxidase subunit I CtaD SW:COX1_BACFI (Q04440) (624 aa) fasta scores: E(): 9.5e-98, 48.56% id in 523 aa, and to Corynebacterium glutamicum cytochrome AA3 oxidase subunit I CtaD TR:Q9AEL9 (EMBL:AJ306417) (584 aa) fasta scores: E(): 1.2e-200, 84.39% id in 564 aa NP_940202.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_940203.1 Similar to Escherichia coli ferritin 1 FtnA SW:FTNA_ECOLI (P23887) (165 aa) fasta scores: E(): 5.9e-10, 29.29% id in 157 aa, and to Methanothermobacter thermautotrophicus ferritin like protein MTH158 TR:O26261 (EMBL:AE000804) (171 aa) fasta scores: E(): 2.6e-17, 36.25% id in 160 aa NP_940204.1 Catalyzes the rate-limiting step in dNTP synthesis NP_940205.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_940206.1 Similar to Escherichia coli glutaredoxin-like protein NrdH SW:NRDH_ECOLI (Q47414) (81 aa) fasta scores: E(): 4.5e-09, 41.66% id in 72 aa, and to Corynebacterium ammoniagenes NrdH-redoxin TR:O69271 (EMBL:Y09572) (75 aa) fasta scores: E(): 4.4e-23, 81.08% id in 74 aa NP_940207.1 Similar to Agrobacterium aurantiacum phytoene synthase CrtB SW:CRTB_AGRAU (P54975) (301 aa) fasta scores: E(): 6.8e-09, 29.57% id in 284 aa, and to Corynebacterium glutamicum phytoene synthase CrtB TR:AAK64298 (EMBL:AF159510) (304 aa) fasta scores: E(): 1.1e-51, 51.22% id in 285 aa NP_940208.1 Similar to Neurospora crassa phytoene dehydrogenase Al-1 SW:CRTI_NEUCR (P21334) (595 aa) fasta scores: E(): 1.6e-33, 29.77% id in 524 aa, and to Corynebacterium glutamicum phytoene desaturase CrtI TR:AAK64299 (EMBL:AF159510) (549 aa) fasta scores: E(): 5.6e-107, 54.59% id in 511 aa NP_940209.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif NP_940210.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_940211.1 Similar to Streptomyces coelicolor hypothetical protein SCJ12.09c TR:Q9RI49 (EMBL:AL109989) (146 aa) fasta scores: E(): 7.2e-10, 38.68% id in 137 aa. C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv3129 TR:O05803 (EMBL:Z95150) (110 aa) fasta scores: E(): 5.1e-11, 47.77% id in 90 aa NP_940212.1 Poor database matches. C-terminal region is similar to Clostridium acetobutylicum hypothetical protein CAC0072 TR:AAK78058 (EMBL:AE007520) (77 aa) fasta scores: E(): 0.01, 29.16% id in 72 aa NP_940213.1 C-terminus is similar to an internal regions of Neisseria gonorrhoeae major anaerobically induced outer membrane protein Pan 1 AniA SW:ANIA_NEIGO (Q02219) (392 aa) fasta scores: E(): 3.5e-18, 30.1% id in 299 aa, and Neisseria meningitidis nitrite reductase, major outer membrane copper-containing protein NMA1887 TR:Q9JTB8 (EMBL:AL162757) (386 aa) fasta scores: E(): 3e-18, 30.43% id in 299 aa NP_940214.1 No significant database matches to the full length CDS. C-terminus is similar to the N-terminal regions of Rhizobium meliloti hypothetical protein SMA0447 TR:AAK64892 (EMBL:AE007216) (373 aa) fasta scores: E(): 0.48, 22.94% id in 353 aa NP_940215.1 Poor database matches. C-terminal region is weakly similar to Sulfolobus solfataricus hypothetical protein Sso2014 sso2014 TR:Q97WV0 (EMBL:AE006808) (307 aa) fasta scores: E(): 0.44, 21.34% id in 328 aa NP_940216.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2621c TR:O06191 (EMBL:Z95387) (224 aa) fasta scores: E(): 2.3e-05, 27.12% id in 188 aa, and to Deinococcus radiodurans conserved hypothetical protein DR0999 TR:Q9RvM8 (EMBL:AE001952) (225 aa) fasta scores: E(): 0.01, 23.62% id in 182 aa NP_940217.1 Poor database matches. Weakly similar to Streptomyces coelicolor hypothetical protein SC4G6.36 TR:Q9S2S3 (EMBL:AL096884) (266 aa) fasta scores: E(): 4.7e-06, 26.22% id in 225 aa, and to Mycobacterium leprae possible conserved membrane protein ML1667 TR:Q9CBS4 (EMBL:AL583923) (264 aa) fasta scores: E(): 1.5e-05, 28.77% id in 212 aa NP_940218.1 Poor database matches. Similar to the N-terminal regions of Paracoccus denitrificans methylamine utilization protein MauE SW:MAUE_PARDE (P29896) (186 aa) fasta scores: E(): 0.00023, 30.89% id in 123 aa, and Methylobacterium extorquens methylamine utilization protein MauE SW:MAUE_METEX (Q49125) (187 aa) fasta scores: E(): 0.026, 29% id in 100 aa NP_940219.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate NP_940220.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_940221.1 Similar to Streptococcus pneumoniae CrcB protein SP1294 TR:AAK75398 (EMBL:AE007428) (109 aa) fasta scores: E(): 7.4e-06, 33.33% id in 108 aa, and to Bacillus subtilis protein CrcB homolog 1 CrcB1 TR:O07590 (EMBL:Y14082) (118 aa) fasta scores: E(): 0.033, 29.56% id in 115 aa NP_940222.1 Similar to Streptomyces coelicolor ABC transport system integral membrane protein SCE41.19c TR:Q9F2P0 (EMBL:AL442120) (854 aa) fasta scores: E(): 6.5e-62, 30.8% id in 870 aa, and to Streptomyces coelicolor ABC transporter integral membrane protein SCE25.31 TR:Q9KZ59 (EMBL:AL354048) (843 aa) fasta scores: E(): 2.6e-41, 33.83% id in 857 aa NP_940223.1 Similar to Streptomyces coelicolor ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 9.4e-54, 63.9% id in 241 aa, and to Streptomyces coelicolor ABC transporter ATP-binding protein SCE25.30 TR:Q9KZ60 (EMBL:AL354048) (256 aa) fasta scores: E(): 4.6e-53, 67.37% id in 236 aa NP_940224.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_940225.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1314c SW:YD14_MYCTU (Q10622) (193 aa) fasta scores: E(): 3.1e-50, 70.15% id in 191 aa, and to Mycobacterium leprae hypothetical protein ML1149 SW:YD14_MYCLE (P53523) (191 aa) fasta scores: E(): 1e-47, 65.96% id in 191 aa NP_940226.1 Similar to Streptomyces coelicolor transcriptional regulator SC2G5.15C TR:Q9Z5A8 (EMBL:AL035478) (279 aa) fasta scores: E(): 9.5e-35, 44.89% id in 274 aa, and to Rhizobium meliloti transcription regulator protein SMC03015 TR:CAC45219 (EMBL:AL591784) (245 aa) fasta scores: E(): 0.012, 25.55% id in 227 aa NP_940227.1 Similar to the C-terminal region of Arabidopsis thaliana cysteine synthase, mitochondrial precursor ACS 1 SW:CYSM_ARATH (Q43725) (424 aa) fasta scores: E(): 1.5e-58, 53.39% id in 309 aa, and to the full length Neisseria meningitidis (serogroup A) cysteine synthase NMA0974 TR:Q9JQL6 (EMBL:AL162754) (310 aa) fasta scores: E(): 5.6e-65, 59.09% id in 308 aa NP_940228.1 Similar to Staphylococcus xylosus serine acetyltransferase CysE SW:CYSE_STAXY (P77985) (216 aa) fasta scores: E(): 9.3e-33, 55.68% id in 167 aa, and to Azotobacter vinelandii O-acetylserine synthase CysE2 TR:O69218 (EMBL:AF010139) (251 aa) fasta scores: E(): 6.1e-38, 58.85% id in 175 aa NP_940229.1 Similar to Streptomyces coelicolor conserved hypothetical protein SC8D11.21 TR:Q9AJZ8 (EMBL:AL512944) (112 aa) fasta scores: E(): 1.5e-08, 40% id in 85 aa, and to Streptomyces coelicolor conserved hypothetical protein SC8D11.19 TR:Q9AK00 (EMBL:AL512944) (102 aa) fasta scores: E(): 1.9e-05, 32.96% id in 91 aa NP_940230.1 Similar to Escherichia coli glycerol dehydrogenase GldA SW:GLDA_ECOLI (P32665) (367 aa) fasta scores: E(): 6.1e-21, 29% id in 331 aa, and to Streptococcus pneumoniae glycerol dehydrogenase SP0253 TR:AAK74432 (EMBL:AE007338) (362 aa) fasta scores: E(): 3e-22, 29.64% id in 361 aa NP_940231.1 No significant database matches to the full length CDS. Internal region is weakly similar to an internal region of Thermoplasma volcanium hypothetical protein TVG1552703 TR:BAB60643 (EMBL:AP000996) (974 aa) fasta scores: E(): 5.5e-05, 21.86% id in 773 aa NP_940232.1 Internal region is similar to an internal regions of Salmonella typhimurium type III restriction-modification system StyLTI enzyme Mod SW:T3MO_SALTY (P40814) (651 aa) fasta scores: E(): 1.8e-20, 29.39% id in 398 aa, and Xylella fastidiosa methyltransferase XF1968 TR:Q9PC17 (EMBL:AE004016) (534 aa) fasta scores: E(): 5.9e-33, 35.25% id in 417 aa NP_940233.1 Similar to the C-terminal regions of Saccharopolyspora sp. transposase SapX TR:O52713 (EMBL:AF045021) (103 aa) fasta scores: E(): 0.00038, 45.83% id in 48 aa, and Streptomyces lividans similar to Orf1 of the IS3 family TR:Q54335 (EMBL:U50076) (103 aa) fasta scores: E(): 0.076, 47.61% id in 42 aa NP_940234.1 Similar to N-terminal region of Corynebacterium jeikeium transposase B TnpB TR:AAK67710 (EMBL:AY036070) (302 aa) fasta scores: E(): 4.1e-08, 40% id in 100 aa. Probable gene remnant NP_940235.1 N-terminus is similar to the N-terminal region of Escherichia coli cytochrome D ubiquinol oxidase subunit I CydA SW:CYDA_ECOLI (P11026) (522 aa) fasta scores: E(): 5.2e-47, 37.11% id in 485 aa. Similar to Mycobacterium tuberculosis probable cytochrome D ubiquinol oxidase subunit Rv1623c TR:O06140 (EMBL:Z95554) (485 aa) fasta scores: E(): 4.5e-121, 62.11% id in 483 aa NP_940236.1 Similar to Escherichia coli cytochrome D ubiquinol oxidase subunit II CydB SW:CYDB_ECOLI (P11027) (379 aa) fasta scores: E(): 9.8e-28, 37.63% id in 364 aa, and to Corynebacterium glutamicum cytochrome BD-type menaquinol oxidase subunit II CydB TR:Q9KWL7 (EMBL:AB035086) (334 aa) fasta scores: E(): 3.4e-63, 54.26% id in 328 aa NP_940237.1 Similar to Bacillus subtilis transport ATP-binding protein CydC SW:CYDC_BACSU (P94366) (567 aa) fasta scores: E(): 2.3e-21, 31.8% id in 544 aa, and to Vibrio cholerae transport ATP-binding protein VC1181 TR:Q9KSS5 (EMBL:AE004198) (595 aa) fasta scores: E(): 2.5e-19, 27.76% id in 551 aa. CDS is extended at the N-terminus in comparison to similar proteins. Possible alternative translational start site NP_940238.1 Similar to Mycobacterium tuberculosis Rv1620c TR:O06137 (EMBL:Z95554) (576 aa) fasta scores: E(): 2.2e-20, 38.71% id in 527 aa, and to Caulobacter crescentus ABC transporter, ATP-binding protein CC0761 TR:Q9AA45 (EMBL:AE005752) (546 aa) fasta scores: E(): 5.8e-16, 28.73% id in 529 aa NP_940239.1 Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 1.8e-85, 47.56% id in 513 aa, and to Caulobacter crescentus coenzyme A transferase, CC3724 SWALL:Q9A242 (EMBL:AE006030) (514 aa) fasta scores: E(): 1.3e-97, 52.96% id in 506 aa NP_940240.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv0823c SW:Y823_MYCTU (O53835) (389 aa) fasta scores: E(): 4.4e-98, 65.69% id in 379 aa, and to Streptomyces coelicolor hypothetical protein SCC82.03c TR:Q9RDC6 (EMBL:AL133471) (406 aa) fasta scores: E(): 3.6e-62, 53.75% id in 400 aa NP_940241.1 Similar to Mycobacterium tuberculosis phosphate transport system protein PhoU homolog 2 Rv0821c SW:PHU2_MYCTU (O53833) (213 aa) fasta scores: E(): 2.1e-32, 42.72% id in 213 aa, and to Mycobacterium leprae phosphate transport system protein PhoU homolog 1 ML2188 SW:PHU1_MYCLE (Q50047) (222 aa) fasta scores: E(): 8.5e-31, 40.93% id in 215 aa NP_940242.1 Doubtful CDS. No significant database matches NP_940243.1 Similar to Escherichia coli phosphate transport system permease PstA SW:PSTA_ECOLI (P07654) (296 aa) fasta scores: E(): 5.5e-27, 35.48% id in 279 aa, and to Mycobacterium tuberculosis phosphate transport system permease Rv0930 TR:AAK45204 (EMBL:X75297) (304 aa) fasta scores: E(): 1.3e-48, 47.65% id in 277 aa. CDS contains a truncated N-terminus in comparison to othologues NP_940244.1 Similar to Escherichia coli, and phosphate transport system permease PstC SW:PSTC_ECOLI (P07653) (319 aa) fasta scores: E(): 3.5e-26, 32.69% id in 312 aa, and to Mycobacterium tuberculosis phosphate transport system permease Rv0929 TR:O86344 (EMBL:Z47983) (324 aa) fasta scores: E(): 2.8e-43, 46.12% id in 310 aa NP_940245.1 Similar to Escherichia coli phosphate-binding periplasmic protein precursor PstS SW:PSTS_ECOLI (P06128) (346 aa) fasta scores: E(): 5e-20, 29.16% id in 360 aa, and to Mycobacterium avium phosphate-binding protein 3 precursor PstS3 TR:Q9KK89 (EMBL:AF137360) (369 aa) fasta scores: E(): 4.6e-50, 42.23% id in 367 aa NP_940246.1 Similar to Mycobacterium leprae acetyltransferase ML2193 TR:Q9CBC9 (EMBL:AL583924) (311 aa) fasta scores: E(): 3.4e-22, 35.5% id in 307 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0819 TR:O53831 (EMBL:AL022004) (315 aa) fasta scores: E(): 6e-19, 33.33% id in 312 aa NP_940247.1 Poor database matches. Similar to Mycobacterium leprae probable exported protein ML2195 TR:Q50040 (EMBL:U15182) (283 aa) fasta scores: E(): 0.44, 23.39% id in 265 aa NP_940248.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3218 TR:O05848 (EMBL:Z95120) (321 aa) fasta scores: E(): 1.1e-27, 33.43% id in 329 aa, and to Streptomyces coelicolor hypothetical protein 2SC7G11.03c TR:Q9F3M0 (EMBL:AL391763) (322 aa) fasta scores: E(): 2.2e-22, 37.69% id in 329 aa NP_940249.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv0813c TR:O53827 (EMBL:AL022004) (226 aa) fasta scores: E(): 2.9e-33, 45.97% id in 211 aa, and to Mycobacterium leprae hypothetical protein ML2200 TR:Q9CBC6 (EMBL:AL583924) (228 aa) fasta scores: E(): 4.3e-32, 43.66% id in 229 aa NP_940250.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate NP_940251.1 Similar to Corynebacterium ammoniagenes hypothetical protein Orf4 TR:Q9RHX9 (EMBL:AB003158) (359 aa) fasta scores: E(): 7.6e-61, 49.17% id in 362 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0811c TR:O53825 (EMBL:AL022004) (368 aa) fasta scores: E(): 7.9e-11, 42.29% id in 357 aa NP_940252.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv0810c TR:O53824 (EMBL:AL022004) (60 aa) fasta scores: E(): 9.9e-07, 49.23% id in 65 aa, and to Streptomyces coelicolor hypothetical protein SCD25.24c TR:Q9RKJ8 (EMBL:AL118514) (84 aa) fasta scores: E(): 2.1e-07, 52.23% id in 67 aa NP_940253.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_940254.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_940255.1 Similar to Corynebacterium ammoniagenes hypothetical protein Orf3 TR:Q9RHY2 (EMBL:AB003158) (132 aa) fasta scores: E(): 4.5e-26, 61.15% id in 121 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0807 TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 2.3e-24, 57.48% id in 127 aa NP_940256.1 Similar to Corynebacterium ammoniagenes hypothetical protein Orf1 TR:Q9RHY4 (EMBL:AB003158) (245 aa) fasta scores: E(): 3.5e-52, 56.65% id in 233 aa, and to Streptomyces coelicolor conserved hypothetical membrane protein 2SCK36.01c TR:CAC40591 (EMBL:AL591857) (234 aa) fasta scores: E(): 2.2e-26, 38.62% id in 233 aa NP_940257.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_940258.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_940259.1 Similar to Caulobacter crescentus glutathione peroxidase CC1730 TR:Q9A7J3 (EMBL:AE005847) (160 aa) fasta scores: E(): 9.7e-24, 45.39% id in 152 aa, and to Pseudomonas aeruginosa glutathione peroxidase PA0838 TR:Q9I5A2 (EMBL:AE004518) (160 aa) fasta scores: E(): 9.7e-24, 44.15% id in 154 aa NP_940260.1 Similar to Mycobacterium tuberculosis CDC1551 protease II MT0805 TR:AAK45047 (EMBL:AE006971) (718 aa) fasta scores: E(): 1.1e-159, 55.68% id in 695 aa, and to Mycobacterium leprae ML2226 TR:O05748 (EMBL:Z95151) (724 aa) fasta scores: E(): 8.2e-148, 52.36% id in 699 aa NP_940261.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_940262.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_940263.1 Similar to Thermus aquaticus aspartate aminotransferase AspC SW:AAT_THETH (Q56232) (385 aa) fasta scores: E(): 1.1e-29, 32.95% id in 352 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3565 TR:P96847 (EMBL:Z92774) (388 aa) fasta scores: E(): 6.4e-68, 48.15% id in 380 aa NP_940264.1 Similar to Bacillus halodurans potassium uptake protein BH2663 TR:Q9K9I4 (EMBL:AP001516) (220 aa) fasta scores: E(): 1.2e-20, 34.29% id in 207 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0939 TR:Q99V10 (EMBL:AP003132) (220 aa) fasta scores: E(): 4.6e-20, 35.09% id in 208 aa NP_940265.1 Similar to Enterococcus hirae V-type sodium ATP synthase subunit J NtpJ SW:NTPJ_ENTHR (P43440) (451 aa) fasta scores: E(): 3.8e-45, 36.94% id in 452 aa, and to Synechocystis sp Na+-ATPase subunit J SLR1509 TR:P73949 (EMBL:D90911) (444 aa) fasta scores: E(): 4.3e-49, 39.68% id in 446 aa NP_940266.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_940267.1 Similar to Rhodococcus sp. S9 HIT-like protein TR:Q9L4T6 (EMBL:AF265258) (141 aa) fasta scores: E(): 1.4e-24, 52.98% id in 134 aa, and to Mycobacterium leprae hypothetical HIT-like protein ML2237 SW:YHI1_MYCLE (P49774) (134 aa) fasta scores: E(): 1.1e-23, 50.37% id in 133 aa NP_940268.1 No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Streptomyces coelicolor secreted lipase SCD63A.10c TR:Q9KY65 (EMBL:AL356832) (331 aa) fasta scores: E(): 0.00018, 31.3% id in 214 aa, and Streptomyces coelicolor lipase 2SCG18.12c TR:Q9K3H5 (EMBL:AL390188) (289 aa) fasta scores: E(): 0.00064, 28.94% id in 190 aa NP_940269.1 C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv0758 TR:P71815 (EMBL:Z80226) (485 aa) fasta scores: E(): 7.7e-38, 42.88% id in 471 aa, and to Bacillus halodurans two-component sensor histidine kinase BH0373 TR:Q9KFU8 (EMBL:AP001508) (459 aa) fasta scores: E(): 3.7e-29, 30.81% id in 464 aa NP_940270.1 Similar to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 1.3e-32, 42.37% id in 236 aa, and to Mycobacterium tuberculosis hypothetical PhoP-like protein Rv0757 TR:AAK45023 (EMBL:Z80226) (240 aa) fasta scores: E(): 3.2e-57, 66.37% id in 226 aa NP_940271.1 Poor database matches. Similar to the C-terminal region of Bacillus subtilis extracellular metalloprotease precursor Mpr SW:MPR_BACSU (P39790) (313 aa) fasta scores: E(): 8.9, 23.76% id in 202 aa NP_940273.1 Similar to the N-terminus of Thermotoga maritima conserved hypothetical protein TM1156 TR:Q9X0P0 (EMBL:AE001773) (129 aa) fasta scores: E(): 5.1e-05, 39.34% id in 61 aa, and to the full length Bacillus subtilis hypothetical protein YvlC TR:O34719 (EMBL:AF017113) (65 aa) fasta scores: E(): 0.00018, 41.37% id in 58 aa NP_940274.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_940275.1 Similar to Salmonella typhimurium methyl viologen resistance protein SmvA SW:SMVA_SALTY (P37594) (496 aa) fasta scores: E(): 4e-41, 33.4% id in 488 aa, and to Pseudomonas aeruginosa probable MFS transporter PA1282 TR:Q9I462 (EMBL:AE004557) (501 aa) fasta scores: E(): 1.2e-55, 41.17% id in 493 aa NP_940276.1 Similar to Synechocystis sp hypothetical protein SLR0895 TR:Q55363 (EMBL:D64003) (187 aa) fasta scores: E(): 6.6e-05, 24% id in 175 aa, and to Rhizobium meliloti hypothetical protein SMC01522 TR:CAC46995 (EMBL:AL591790) (186 aa) fasta scores: E(): 7.7e-05, 25.88% id in 170 aa NP_940277.1 Similar to Streptomyces coelicolor permease SC9G1.04 TR:Q9RKW2 (EMBL:AL132997) (462 aa) fasta scores: E(): 5.6e-61, 41.93% id in 465 aa, and to Escherichia coli purine permease YgfU SW:YGFU_ECOLI (Q46821) (482 aa) fasta scores: E(): 9e-55, 38.08% id in 449 aa NP_940278.1 Almost identical to Salmonella enterica subsp enterica serovar Typhimurium transposase TnpA TR:Q9FDH9 (EMBL:AF261825) (264 aa) fasta scores: E(): 7e-112, 99.62% id in 264 aa, and to Mycobacterium fortuitum transposase Tnp TR:Q49185 (EMBL:X53635) (254 aa) fasta scores: E(): 6.7e-107, 99.6% id in 254 aa. Note: This CDS is duplicated downstream in CDIP1951 (264 aa) fasta scores: E(): 2.7e-119, 100.000% identity in 264 aa overlap NP_940279.1 N-terminus is identical to the N-terminal regions of Mycobacterium fortuitum integrase Orf2M TR:Q49186 (EMBL:X53635) (303 aa) fasta scores: E(): 3.6e-79, 100% id in 194 aa, and Acinetobacter baumannii integraseTtnp1 TR:AAA56784 (EMBL:U17586) (337 aa) fasta scores: E(): 4e-79, 100% id in 194 aa NP_940280.1 Almost identical to Escherichia coli dihydropteroate synthase type I SulI SW:DHP1_ECOLI (P11744) (279 aa) fasta scores: E(): 3.1e-105, 99.64% id in 278 aa, and to Corynebacterium glutamicum sufamethoxazole resistance protein SulI TR:AAG00283 (EMBL:AF164956) (279 aa) fasta scores: E(): 3.1e-105, 99.64% id in 278 aa. Orthologues are implicated in resistance to sulfonamide and are located on various large self-transmissible plasmids and transposons related to Tn21 NP_940281.1 Identical to Escherichia coli hypothetical protein YbbA TR:P75025 (EMBL:U12441) (166 aa) fasta scores: E(): 1.6e-70, 100% id in 166 aa, and to Acinetobacter baumannii hypothetical protein TR:AAK72477 (EMBL:AY038837) (142 aa) fasta scores: E(): 4.2e-59, 100% id in 142 aa NP_940282.1 Poor database matches. Identical to Salmonella enterica subsp enterica serovar Typhimurium hypothetical protein TR:Q9FDI0 (EMBL:AF261825) (95 aa) fasta scores: E(): 3.9e-37, 100% id in 95 aa NP_940283.1 Almost identical to Salmonella enterica subsp enterica serovar Typhimurium transposase TnpA TR:Q9FDH9 (EMBL:AF261825) (264 aa) fasta scores: E(): 6.6e-112, 99.62% id in 264 aa, and Mycobacterium fortuitum transposase Tnp TR:Q49185 (EMBL:X53635) (254 aa) fasta scores: E(): 6.4e-107, 99.6% id in 254 aa, Note: This CDS is duplicated upstream in CDIP1944 (264 aa) fasta scores: E(): 2.7e-119, 100.000% identity in 264 aa overlap NP_940284.1 catalyzes the formation of acetate from pyruvate NP_940285.1 Similar to Corynebacterium glutamicum threonine export carrier protein ThrE TR:AAK61331 (EMBL:AF326510) (489 aa) fasta scores: E(): 3.8e-75, 48.76% id in 445 aa, and to Mycobacterium tuberculosis membrane protein Rv3737 TR:O69704 (EMBL:AL022121) (529 aa) fasta scores: E(): 2.2e-29, 31.15% id in 414 aa. Note: Also similar to DIP1964 (514 aa) fasta scores: E(): 7.1e-58, 44.662% identity in 459 aa overlap NP_940286.1 Similar to Escherichia coli transposase for insertion sequence element IS150, InsK SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 3.2e-41, 43.23% id in 266 aa, and to Klebsiella pneumoniae hypothetical protein OrfB TR:Q9AG21 (EMBL:AF345899) (281 aa) fasta scores: E(): 1.3e-42, 45.45% id in 264 aa. CDS contains fewer amino acids at the N-terminus in comparison to orthologues NP_940287.1 C-terminal regions is similar to Streptococcus agalactiae hypothetical protein TR:Q53639 (EMBL:M22449) (141 aa) fasta scores: E(): 1.3e-06, 32.43% id in 111 aa, and to Marinococcus halophilus transposase TR:O06062 (EMBL:U66614) (110 aa) fasta scores: E(): 0.051, 27.18% id in 103 aa NP_940290.1 Poor database matches. Similar to the C-terminal region of Bacillus halodurans hypothetical protein BH3550 TR:Q9K723 (EMBL:AP001519) (146 aa) fasta scores: E(): 0.85, 32.03% id in 103 aa NP_940291.1 C-terminus is similar to the C-terminal region of Bacillus subtilis hypothetical protein YqxI SW:YQXI_BACSU (P24812) (159 aa) fasta scores: E(): 7.6, 26.04% id in 96 aa NP_940294.1 Similar to Escherichia coli possible transposase of IS1353 YahA TR:Q9WTH9 (EMBL:AP000342) (514 aa) fasta scores: E(): 1.7e-62, 41.81% id in 464 aa, and to Agrobacterium tumefaciens str. C58 possible transposase of IS1353 AGR_C_3822 TR:AAK87856 (EMBL:AE008127) (512 aa) fasta scores: E(): 2.7e-58, 39.13% id in 460 aa NP_940295.1 Similar to Corynebacterium glutamicum ThrEonine export carrier protein ThrE TR:AAK61331 (EMBL:AF326510) (489 aa) fasta scores: E(): 7e-110, 63.45% id in 487 aa, and to Mycobacterium tuberculosis membrane protein Rv3737 TR:O69704 (EMBL:AL022121) (529 aa) fasta scores: E(): 1.6e-37, 36.1% id in 421 aa. Note: Also similar to DIP1953 (483 aa) fasta scores: E(): 3.6e-61, 44.662% identity in 459 aa overlap NP_940296.1 Limited database matches. Similar to Chlamydia muridarum histone H1-like protein TC0119 SW:HCT1_CHLMU (Q9PLI1) (125 aa) fasta scores: E(): 0.19, 35.39% id in 113 aa, and to Chlamydia trachomatis histone H1-like protein CT743 SW:HCT1_CHLTR (Q02281) (125 aa) fasta scores: E(): 0.22, 35.39% id in 113 aa. CDS contains a C-terminal lysine rich region NP_940297.1 Similar to Schizosaccharomyces pombe alpha,alpha-trehalose-phosphate synthase [UDP-forming] TPS1 SW:TPS1_SCHPO (P40387) (513 aa) fasta scores: E(): 7e-55, 36.68% id in 477 aa, and to Mycobacterium tuberculosis alpha,alpha-trehalose-phosphate synthase Rv3490 TR:O06353 (EMBL:Z95390) (500 aa) fasta scores: E(): 3.1e-98, 55.18% id in 482 aa NP_940299.1 Similar to Escherichia coli trehalose-phosphatase OtsB SW:OTSB_ECOLI (P31678) (266 aa) fasta scores: E(): 1.8e-10, 30.3% id in 231 aa, and to Salmonella typhimurium trehalose-phosphatase STM1929 SW:OTSB_SALTY (Q9L894) (267 aa) fasta scores: E(): 5.1e-11, 29.78% id in 235 aa NP_940300.1 Similar to Escherichia coli raffinose operon repressor RafR SW:RAFR_ECOLI (P21867) (335 aa) fasta scores: E(): 1.5e-08, 24.52% id in 367 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3575c TR:P96857 (EMBL:Z92774) (359 aa) fasta scores: E(): 1.8e-50, 45.82% id in 371 aa NP_940301.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3579c TR:P96861 (EMBL:Z92774) (322 aa) fasta scores: E(): 1.1e-61, 58.33% id in 312 aa, and to Streptomyces coelicolor tRNA/rRNA methyltransferase SCD8A.09 TR:Q9L0Q5 (EMBL:AL160331) (314 aa) fasta scores: E(): 2.7e-57, 55.97% id in 318 aa NP_940302.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_940303.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_940304.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_940305.1 N-terminal region is similar to Mycobacterium tuberculosis transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa NP_940307.1 No significant database matches to the full length CDS. Internal region is similar to the C-terminal region of Streptococcus pneumoniae surface protein PspC TR:Q9KK25 (EMBL:AF154033) (763 aa) fasta scores: E(): 0.081, 25.23% id in 214 aa NP_940308.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_940309.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3587c TR:O53572 (EMBL:AL022075) (264 aa) fasta scores: E(): 2.9e-10, 29.13% id in 230 aa, and to Mycobacterium leprae hypothetical membrane protein ML1918 TR:Q9CBJ2 (EMBL:AL583923) (263 aa) fasta scores: E(): 1e-08, 28.69% id in 230 aa NP_940310.1 Similar to Mycobacterium tuberculosis carbonic anhydrase Rv3588c TR:O53573 (EMBL:AL022075) (207 aa) fasta scores: E(): 6.4e-31, 46.31% id in 190 aa. Weakly similar to Escherichia coli carbonic anhydrase CynT SW:CYNT_ECOLI (P17582) (219 aa) fasta scores: E(): 2.8e-09, 32.22% id in 180 aa NP_940311.1 Similar to Mycobacterium leprae probable DNA glycosylase ML1920 TR:Q9CBJ0 (EMBL:AL583923) (297 aa) fasta scores: E(): 5.3e-52, 51.86% id in 295 aa. N-terminus is similar to the N-terminal region of Escherichia coli A/G-specific adenine glycosylase MutY SW:MUTY_ECOLI (P17802) (350 aa) fasta scores: E(): 2.9e-23, 40.48% id in 205 aa NP_940312.1 N-terminus is similar to the C-terminal region of Rhodobacter capsulatus hypothetical 31.0 kDa protein TR:O68029 (EMBL:AF010496) (289 aa) fasta scores: E(): 5.3e-10, 28.39% id in 243 aa, and to the full length Escherichia coli hypothetical protein YjjP SW:YJJP_ECOLI (P39402) (256 aa) fasta scores: E(): 1.3e-08, 27.16% id in 254 aa NP_940313.1 Poor database matches. Similar to the N-terminal region of Escherichia coli O157:H7 hypothetical protein ECS1344 TR:BAB34767 (EMBL:AE005309) (402 aa) fasta scores: E(): 9.6, 38.33% id in 60 aa. Doubtful CDS NP_940314.1 Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa NP_940315.1 Similar to Pasteurella multocida hypothetical protein PM0821 TR:Q9CMK3 (EMBL:AE006121) (150 aa) fasta scores: E(): 8.8e-19, 46% id in 150 aa, and to Deinococcus radiodurans conserved hypothetical protein DR1979 TR:Q9RSZ0 (EMBL:AE002036) (161 aa) fasta scores: E(): 8.6e-16, 42.66% id in 150 aa NP_940316.1 Poor database matches. C-terminal region is similar to Rhizobium loti hypothetical protein MLL0061 TR:Q98NN3 (EMBL:AP002994) (97 aa) fasta scores: E(): 1.7, 25% id in 96 aa. Possible alternative translational start site NP_940317.1 Similar to Homo sapiens monoglyceride lipase TR:CAC43316 (EMBL:AJ270950) (303 aa) fasta scores: E(): 1.6e-14, 28.88% id in 277 aa, and to Deinococcus radiodurans lipase DR1537 TR:Q9RU57 (EMBL:AE001997) (282 aa) fasta scores: E(): 4.2e-24, 33.69% id in 276 aa NP_940318.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_940319.1 No significant database matches to the full length CDS. N-terminus is similar to the N-terminal region of Streptomyces coelicolor insertion element IS110 hypothetical protein SC3C8.10 SW:YIS1_STRCO (P19780) (405 aa) fasta scores: E(): 8.1e-15, 42.33% id in 137 aa, and to Shigella flexneri transposase for IS110 S0128 TR:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 4.6e-14, 40.87% id in 137 aa NP_940320.1 Weakly similar to Streptomyces coelicolor ABC transporter integral membrane protein SCC30.14 TR:Q9L007 (EMBL:AL352972) (238 aa) fasta scores: E(): 1.9e-11, 28.91% id in 249 aa, and to Bacillus cereus hypothetical protein YvfS TR:Q9L4F5 (EMBL:AJ243712) (239 aa) fasta scores: E(): 3.1e-08, 23.79% id in 248 aa NP_940321.1 Similar to Rhizobium sp nodulation ATP-binding protein I NodI SW:NODI_RHIS3 (P72335) (304 aa) fasta scores: E(): 6.6e-22, 35.94% id in 306 aa, and to Streptomyces coelicolor ABC transporter ATP-binding subunit SCC30.13 TR:Q9L008 (EMBL:AL352972) (308 aa) fasta scores: E(): 2.8e-31, 39.34% id in 305 aa NP_940322.1 Similar to Streptomyces coelicolor transmembrane protein SCK7.11c TR:Q9KIM1 (EMBL:AF230489) (312 aa) fasta scores: E(): 4.5e-47, 50.16% id in 301 aa. C-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP2132 TR:AAK76190 (EMBL:AE007502) (335 aa) fasta scores: E(): 8.7e-22, 42.43% id in 304 aa NP_940323.1 C-terminal region is similar to Escherichia coli proton glutamate symport protein GltP SW:GLTP_ECOLI (P21345) (437 aa) fasta scores: E(): 2.5e-34, 29.25% id in 417 aa, and to the C-terminal region of Caulobacter crescentus sodium:dicarboxylate symporter family protein CC1104 TR:Q9A990 (EMBL:AE005788) (476 aa) fasta scores: E(): 1.4e-90, 57.93% id in 435 aa. Possible alternative translational start site NP_940324.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_940325.1 Poor database matches. N-terminus is similar to the C-terminal region of Pseudomonas aeruginosa malonate decarboxylase alpha subunit PA0208 TR:Q9I6T0 (EMBL:AE004459) (554 aa) fasta scores: E(): 3.7, 32.31% id in 164 aa NP_940326.1 Weakly similar to the N-terminal regions of Mycobacterium leprae membrane protein ML0228 TR:O69526 (EMBL:AL023093) (432 aa) fasta scores: E(): 0.025, 25.15% id in 318 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3709 TR:AAK48067 (EMBL:AE007170) (397 aa) fasta scores: E(): 0.071, 23.51% id in 336 aa NP_940327.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3605c TR:O06277 (EMBL:Z95557) (158 aa) fasta scores: E(): 1.3e-11, 39% id in 141 aa, and to Mycobacterium leprae hypothetical protein ML0227 TR:O69527 (EMBL:AL023093) (158 aa) fasta scores: E(): 5.6e-11, 36.73% id in 147 aa NP_940328.1 Similar to Escherichia coli 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK SW:HPPK_ECOLI (P26281) (158 aa) fasta scores: E(): 1.1e-11, 36.36% id in 154 aa, and to Mycobacterium tuberculosis 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Rv3606c SW:HPPK_MYCTU (O06276) (188 aa) fasta scores: E(): 6e-23, 48.93% id in 141 aa NP_940329.1 Similar to Corynebacterium glutamicum dihydroneopterin aldolase CGL2693 SWALL:BAC00087 (EMBL:AP005282) (130 aa) fasta scores: E(): 1.3e-30, 66.11% id in 121 aa, and to Bacillus subtilis dihydroneopterin aldolase FolB or FolA SWALL:FOLB_BACSU (SWALL:P28823) (120 aa) fasta scores: E(): 2.4e-14, 38.98% id in 118 aa NP_940330.1 Similar to Mycobacterium tuberculosis dihydropteroate synthase 1 FolP1 SW:DHP1_MYCTU (O06274) (280 aa) fasta scores: E(): 4.3e-48, 53.9% id in 269 aa, and to Streptomyces coelicolor dihydropteroate synthase SCE9.05 TR:Q9X8H8 (EMBL:AL049841) (288 aa) fasta scores: E(): 6.9e-46, 53.75% id in 266 aa NP_940331.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_940332.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_940333.1 Similar to Mycobacterium tuberculosis cell division protein FtsH homolog Rv3610c SW:FTSH_MYCTU (P96942) (760 aa) fasta scores: E(): 8e-126, 59.01% id in 793 aa, and to Mycobacterium leprae cell division protein FtsH TR:O69532 (EMBL:AL023093) (787 aa) fasta scores: E(): 2.6e-126, 57.03% id in 817 aa NP_940334.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively NP_940335.1 Similar to Mycobacterium tuberculosis hypothetical 34.1 kDa protein Rv3625c or MT3727 or MTCY15C10.27 SWALL:Y0C5_MYCTU (SWALL:O06382) (323 aa) fasta scores: E(): 5.3e-28, 45.2% id in 292 aa, and to Streptomyces coelicolor hypothetical 36.7 kDa protein SCE9.13c SWALL:Q9X8I6 (EMBL:AL049841) (352 aa) fasta scores: E(): 1.6e-07, 38.72% id in 297 aa NP_940336.1 Similar to Mycobacterium tuberculosis hypothetical 46.8 kDa protein Rv3627c or MT3729 or MTCY15C10.25 SWALL:AAK48090 (EMBL:Z95436) (461 aa) fasta scores: E(): 5.2e-11, 37.04% id in 440 aa, and to Escherichia coli penicillin-binding protein 4 precursor DacB or B3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 4.4e-05, 26.55% id in 433 aa NP_940337.1 Catalyzes the hydrolysis of pyrophosphate NP_940338.1 Similar to Streptomyces coelicolor hypothetical 11.5 kDa protein SCH69.09c SWALL:Q9XA25 (EMBL:AL079308) (109 aa) fasta scores: E(): 4.5e-11, 43.29% id in 97 aa, and to Bacillus subtilis hypothetical 14.6 kDa protein in gcvT-spoIIIAA intergenic region YqhL SWALL:YQHL_BACSU (SWALL:P54510) (126 aa) fasta scores: E(): 4.4e-07, 39.13% id in 92 aa NP_940339.1 Similar to Caulobacter crescentus transcriptional regulator, MarR family CC3677 SWALL:Q9A289 (EMBL:AE006025) (186 aa) fasta scores: E(): 5.8e-05, 29.75% id in 121 aa, and to Escherichia coli multiple antibiotic resistance protein MarR or SoxQ or CfxB or InaR or B1530 SWALL:MARR_ECOLI (SWALL:P27245) (144 aa) fasta scores: E(): 0.00044, 30.35% id in 112 aa NP_940340.1 N-terminal region similar to C-terminal region of Streptomyces lavendulae peptide synthetase SWALL:AAK81825 (EMBL:AF386507) (1531 aa) fasta scores: E(): 1.3e-38, 34.02% id in 814 aa, similar in its full length to Agrobacterium tumefaciens StrC58 AGR_l_3476p SWALL:AAK90311 (EMBL:AE008376) (1344 aa) fasta scores: E(): 6.2e-36, 32.96% id in 1338 aa, and N-terminal region similar to the full length of Amycolatopsis orientalis PCZA361.18 SWALL:O52803 (EMBL:AJ223998) (580 aa) fasta scores: E(): 1.3e-33, 38.2% id in 589 aa. C-terminal region presents low similarity database matches to Rhizobium loti (Mesorhizobium loti) peptide synthetase SWALL:Q98JF4 (1325 aa) blastp scores: E(): 3e-13, Identities = 77/327 (23%), Positives = 127/327 (38%) NP_940341.1 Similar to Actinomyces viscosus usher-like protein precursor TR:Q9AJ93 (EMBL:AF106034) (1411 aa) fasta scores: E(): 0.034, 22.657% id in 843 aa, and to Actinomyces naeslundii fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.14, 25.131% id in 191 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain NP_940342.1 No significant database matches. Note: Contains a potential sortase anchor site (LAFTG) upstream of the C-terminal region transmembrane domain NP_940343.1 Similar to Actinomyces viscosus sortase-like protein SWALL:Q9AJ92 (EMBL:AF106034) (387 aa) fasta scores: E(): 2.7e-39, 43.47% id in 276 aa, and to Bifidobacterium longum NCC2705 sortase-like protein BL0676 SWALL:AAN24497 (EMBL:AE014690) (328 aa) fasta scores: E(): 3.7e-28, 36.94% id in 268 aa, and to Streptococcus pneumoniae sortase, SP0466 SWALL:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 3e-21, 31.78% id in 258 aa NP_940344.1 Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 4.4e-20, 28.827% id in 503 aa, and to Actinomyces naeslundii type-1 fimbrial major subunit precursor FimP TR:Q9X4D8 (EMBL:AF107019) (533 aa) fasta scores: E(): 8.5e-15, 27.432% id in 514 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain NP_940346.1 Similar to Streptomyces coelicolor secreted protein SC10G8.24c TR:Q9L181 (EMBL:AL158057) (445 aa) fasta scores: E(): 7.7e-31, 35.363% id in 427 aa, and to Saccharopolyspora spinosa SpnM TR:Q9ALN4 (EMBL:AY007564) (320 aa) fasta scores: E(): 2.2e-23, 36.111% id in 288 aa, and to Candida albicans secretory lipase 5 Lip5 TR:Q9P8W0 (EMBL:AF191318) (463 aa) fasta scores: E(): 2.1e-17, 24.877% id in 406 aa NP_940347.1 Similar to Pseudomonas aeruginosa hypothetical protein PA0141 SWALL:Q9I6Z1 (EMBL:AE004452) (298 aa) fasta scores: E(): 1.2e-69, 62.06% id in 261 aa, and to Rhizobium loti MLL5641 protein SWALL:Q98BC2 (EMBL:AP003007) (302 aa) fasta scores: E(): 9.2e-57, 49.63% id in 274 aa NP_940348.1 Similar to Mycobacterium leprae hypothetical protein ML2321 SWALL:Q9CB79 (EMBL:AL583925) (336 aa) fasta scores: E(): 5.7e-12, 29.15% id in 343 aa NP_940349.1 Doubtful CDS. No significant database matches NP_940350.1 Similar to Rhizobium loti transposase MLR9644 SWALL:Q98P21 (EMBL:AP003017) (103 aa) fasta scores: E(): 7, 30.58% id in 85 aa NP_940351.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_940352.1 Similar to Corynebacterium jeikeium YkwC SWALL:AAK94053 (EMBL:AF401314) (102 aa) fasta scores: E(): 2.3e-06, 64.28% id in 42 aa NP_940354.1 Similar to the central domain of Arthrobacter keyseri hypothetical 45.9 kDa protein TnpX SWALL:Q9AGM1 (EMBL:AF331043) (421 aa) fasta scores: E(): 2.1e-12, 35.44% id in 237 aa NP_940356.1 Similar to Pseudomonas aeruginosa hypothetical protein PA4583 SWALL:Q9HVK1 (EMBL:AE004872) (404 aa) fasta scores: E(): 7.5e-64, 45.92% id in 405 aa, and to Escherichia coli protein RtcB or B3421 SWALL:RTCB_ECOLI (SWALL:P46850) (408 aa) fasta scores: E(): 6e-45, 46.75% id in 385 aa NP_940357.1 Similar to Xylella fastidiosa NAD(P)H-dependent 2-cyclohexen-1-one reductase XF1732 SWALL:Q9PCP6 (EMBL:AE003996) (368 aa) fasta scores: E(): 1.3e-62, 50.56% id in 356 aa, and to Pseudomonas syringae NAD(P)H-dependent 2-cyclohexen-1-one reductase Ncr SWALL:Q9Z3T1 (EMBL:AF093246) (360 aa) fasta scores: E(): 4e-45, 40.54% id in 365 aa NP_940358.1 Similar to Pseudomonas lemoignei excinuclease ABC subunit A UvrA SWALL:UVRA_PSELE (SWALL:P52087) (689 aa) fasta scores: E(): 1.1e-73, 60.02% id in 703 aa, and to Micrococcus luteus excinuclease ABC subunit A UvrA SWALL:UVRA_MICLU (SWALL:P13567) (992 aa) fasta scores: E(): 8.7e-50, 38.63% id in 1012 aa, and to Streptomyces coelicolor excinuclease ABC subunit A Uvra or SCC54.18c SWALL:UVRA_STRCO (SWALL:Q9Z507) (1014 aa) fasta scores: E(): 2.8e-49, 39.67% id in 993 aa NP_940359.1 Similar to Pseudomonas aeruginosa probable protease PA4171 SWALL:Q9HWL0 (EMBL:AE004833) (187 aa) fasta scores: E(): 3.2e-25, 50.28% id in 175 aa, and to Pyrococcus furiosus protease I PfpI or PF1719 SWALL:PFPI_PYRFU (SWALL:Q51732) (166 aa) fasta scores: E(): 1.8e-19, 40.58% id in 170 aa NP_940360.1 Similar partially to the C-terminal region of Saccharopolyspora sp transposase SapX SWALL:O52713 (EMBL:AF045021) (103 aa) fasta scores: E(): 1.3e-06, 58.53% id in 41 aa, and to Mycobacterium tuberculosis insertion element IS986 hypothetical 6.6 kDa protein SWALL:YIA2_MYCTU (SWALL:P19772) (59 aa) fasta scores: E(): 9.5e-05, 60% id in 35 aa NP_940362.1 Similar to Streptomyces coelicolor peptidase SCG22.20 SWALL:Q9K425 (EMBL:AL359779) (451 aa) fasta scores: E(): 5.7e-70, 44.19% id in 448 aa, and to Mycobacterium leprae hypothetical 46.6 kDa protein ML1193 or MLCB458.08 SWALL:Q9X7E4 (EMBL:AL049478) (442 aa) fasta scores: E(): 1.1e-52, 37.41% id in 441 aa NP_940363.1 Doubtful CDS. No strong consensus RBS usptream. No significant database matches NP_940365.1 Similar to Mycobacterium leprae probable conserved membrane protein ML1504 SWALL:Q9CBX0 (EMBL:AL583922) (430 aa) fasta scores: E(): 1.8e-10, 31.8% id in 349 aa, and to Mycobacterium tuberculosis hypothetical 47.1 kDa protein Rv1159 or MT1195 or MTCI65.26 SWALL:O06557 (EMBL:Z95584) (431 aa) fasta scores: E(): 4.3e-10, 31.66% id in 360 aa NP_940366.1 ATP-dependent carboxylate-amine ligase NP_940368.1 Similar to Streptomyces coelicolor hypothetical 9.6 kDa protein SCD95A.20 SWALL:Q9KXV4 (EMBL:AL357432) (84 aa) fasta scores: E(): 1e-08, 54.09% id in 61 aa, and to Mycobacterium tuberculosis hypothetical 11.7 kDa protein Rv0430 or MT0445 or MTCY22G10.27 SWALL:P96276 (EMBL:Z84724) (102 aa) fasta scores: E(): 2.2e-07, 48.38% id in 62 aa NP_940369.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_940370.1 Similar to Mycobacterium tuberculosis hypothetical 32.6 kDa protein Rv0428c or MT0443 or MTCY22G10.25c SWALL:P96274 (EMBL:Z84724) (302 aa) fasta scores: E(): 2.7e-22, 34.53% id in 304 aa, and to Caulobacter crescentus acetyltransferase, GNAT family CC2209 SWALL:Q9A685 (EMBL:AE005892) (207 aa) fasta scores: E(): 2.4e-06, 30.76% id in 208 aa NP_940371.1 Similar to Streptomyces coelicolor exonuclease SC3A7.09 SWALL:O86610 (EMBL:AL031155) (259 aa) fasta scores: E(): 4.4e-32, 51.93% id in 258 aa, and to Mycobacterium tuberculosis CDC1551 exodeoxyribonuclease III MT0442 SWALL:AAK44665 (EMBL:AE006947) (291 aa) fasta scores: E(): 1.2e-25, 54.16% id in 264 aa NP_940372.1 Similar to Xylella fastidiosa cardiolipin synthase XF1209 SWALL:Q9PE19 (EMBL:AE003954) (467 aa) fasta scores: E(): 3.2e-52, 35.02% id in 474 aa, and to Bacillus firmus cardiolipin synthetase Cls SWALL:CLS_BACFI (SWALL:O66043) (503 aa) fasta scores: E(): 3.4e-41, 30.56% id in 494 aa, and to Escherichia coli cardiolipin synthetase Cls or Nov or B1249 SWALL:CLS_ECOLI (SWALL:P31071) (486 aa) fasta scores: E(): 2.6e-37, 27.18% id in 493 aa NP_940373.1 Low similarity to Streptomyces coelicolor ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa NP_940374.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding subunit 2SC6G5.39c SWALL:Q9K4B6 (EMBL:AL359152) (346 aa) fasta scores: E(): 9.3e-56, 60% id in 305 aa, and to Bacillus sphaericus CDD4-like protein SWALL:Q9Z5R0 (EMBL:AJ224479) (311 aa) fasta scores: E(): 7.9e-29, 37.45% id in 299 aa NP_940375.1 Similar to Mycobacterium leprae membrane protein MLCB1450.21c SWALL:Q9ZBL6 (EMBL:AL035159) (403 aa) fasta scores: E(): 3.4e-22, 32.51% id in 406 aa, and to Mycobacterium tuberculosis hypothetical 47.1 kDa protein Rv0412c or MT0425 or MTCY22G10.08c SWALL:AAK44649 (EMBL:Z84724) (439 aa) fasta scores: E(): 3.1e-21, 33.09% id in 414 aa NP_940376.1 Similar to Mycobacterium tuberculosis CDC1551 amino acid ABC transporter, amino acid-binding protein MT0424 SWALL:AAK44648 (EMBL:AE006946) (328 aa) fasta scores: E(): 1.5e-33, 41.84% id in 325 aa, and to Bacillus stearothermophilus glutamine-binding protein precursor GlnH SWALL:GLNH_BACST (SWALL:P27676) (262 aa) fasta scores: E(): 5.3e-19, 31.25% id in 240 aa NP_940377.1 Similar to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknG or Rv0410c or MT0423 or MTCY22G10.06c SWALL:PKNG_MYCTU (SWALL:P96256) (750 aa) fasta scores: E(): 2.8e-52, 44.97% id in 656 aa, and to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknL or Rv2176 or MT2232 or MTV021.09 SWALL:PKNL_MYCTU (SWALL:O53510) (399 aa) fasta scores: E(): 4e-06, 28.61% id in 318 aa NP_940378.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_940379.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta NP_940380.1 Similar to Streptomyces coelicolor ferredoxin/ferredoxin-NADP reductase SCF15.02 SWALL:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 4e-107, 59.95% id in 452 aa, and to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SWALL:ADRO_RAT (SWALL:P56522) (494 aa) fasta scores: E(): 1.3e-42, 36.02% id in 458 aa, and to Mycobacterium tuberculosis probable ferredoxin/ferredoxin--NADP reductase FprB or Rv0886 or MT0909 or MTCY31.14 SWALL:FPRB_MYCTU (SWALL:Q10547) (575 aa) fasta scores: E(): 2.1e-33, 35.98% id in 453 aa NP_940381.1 Similar to although shorter in its N-terminal region than Pasteurella haemolytica probable phosphoribosylglycinamide formyltransferase 2 PurT or Mpa1 SWALL:PURT_PASHA (SWALL:P46927) (392 aa) fasta scores: E(): 1e-12, 32.24% id in 276 aa, than Bacillus subtilis phosphoribosylglycinamide formyltransferase 2 PurT SWALL:PURT_BACSU (SWALL:P39771) (384 aa) fasta scores: E(): 3.8e-12, 35.81% id in 282 aa, and than Escherichia coli phosphoribosylglycinamide formyltransferase 2 PurT or B1849 SWALL:PURT_ECOLI (SWALL:P33221) (391 aa) fasta scores: E(): 1.2e-09, 29.82% id in 285 aa NP_940382.1 Similar to Streptomyces coelicolor purine phosphoribosyltransferase SCH35.47 SWALL:Q9X8V9 (EMBL:AL078610) (165 aa) fasta scores: E(): 1.1e-27, 52.25% id in 155 aa, and to Aeropyrum pernix 272aa long hypothetical hypoxanthine phosphoribosyltransferase APE2071 SWALL:Q9YA68 (EMBL:AP000063) (272 aa) fasta scores: E(): 3.8e-16, 36.47% id in 159 aa NP_940383.1 No significant database matches. Note: Also similar to DIP0167 (259 aa) E(): 4.6e-41; 44.747% identity in 257 aa overlap NP_940384.1 Low similarity to Campylobacter jejuni membrane protein CjaE SWALL:Q9RM70 (EMBL:AJ249744) (505 aa) fasta scores: E(): 3.1e-24, 28.45% id in 471 aa NP_940385.1 Similar to Helicobacter pylori hypothetical 6.1 kDa protein HP0594 SWALL:O25316 (EMBL:AE000573) (54 aa) fasta scores: E(): 0.026, 32.72% id in 55 aa, and to Campylobacter jejuni small hydrophobic protein CJ0018c SWALL:Q9PJ93 (EMBL:AL139074) (55 aa) fasta scores: E(): 0.046, 35.71% id in 56 aa. Note: Highly hydrophobic NP_940386.1 Low similarity to Streptococcus agalactiae BPS protein precursor Sar5 TR:Q9XAS7 (EMBL:AJ133114) (979 aa) fasta scores: E(): 7.1e-12, 32.35% id in 442 aa, and to Staphylococcus epidermidis cell-surface adhesin SdrF TR:Q9KI14 (EMBL:AF245041) (1733 aa) fasta scores: E(): 0.015, 24.86% id in 539 aa. Note: Contains a potential sortase anchor site (LAATG) upstream of the C-terminal region transmembrane domain NP_940387.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_940388.1 Similar to part of several beta-ketoacyl-ACP synthases e.g. Streptomyces coelicolor actinorhodin polyketide beta-ketoacyl synthase 1 SW:KASA_STRCO (Q02059) (424 aa) fasta scores: E(): 2.1, 31.343% id in 67 aa, and to Arabidopsis thaliana 3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplast precursor Kas1 SW:FABB_ARATH (P52410) (473 aa) fasta scores: E(): 5.8, 27.273% id in 77 aa NP_940389.1 Similar to part of several hyrolases e.g. Rhodococcus globerulus 2-hydroxy-6-ketonona-2,4-dienoate hydrolase HppC TR:O05145 (EMBL:U89712) (288 aa) fasta scores: E(): 3.9e-15, 80.000% id in 45 aa, and to Pseudomonas putida 2-hydroxymuconic semialdehyde hydrolase XylF SW:XYLF_PSEPU (P23106) (281 aa) fasta scores: E(): 0.00093, 41.667% id in 36 aa NP_940390.1 Some similarity to Actinomyces naeslundii fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.0012, 28.803% id in 309 aa. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain NP_940391.1 Similar to Mycobacterium leprae hypothetical 25.3 kDa protein ML0281 or MLCB4.24 SWALL:O69596 (EMBL:AL023514) (229 aa) fasta scores: E(): 6.1e-08, 36.63% id in 202 aa NP_940392.1 Similar to Corynebacterium glutamicum hypothetical protein in fda 3'region SWALL:YFDA_CORGL (SWALL:Q99340) (359 aa) fasta scores: E(): 4.8e-63, 51.61% id in 341 aa, and to Mycobacterium tuberculosis hypothetical 36.8 kDa protein Rv2571c or MT2647 or MTCY227.30 SWALL:YP71_MYCTU (SWALL:Q50650) (355 aa) fasta scores: E(): 1.1e-12, 25.07% id in 331 aa. Note: Also similar to DIP2070 (393 aa) E(): 8.6e-66; 52.174% identity in 368 aa overlap NP_940394.1 Similar to Corynebacterium glutamicum hypothetical protein in fda 3'region SWALL:YFDA_CORGL (SWALL:Q99340) (359 aa) fasta scores: E(): 8.6e-62, 48.97% id in 341 aa, and to Mycobacterium tuberculosis hypothetical 36.8 kDa protein Rv2571c or MT2647 or MTCY227.30 SWALL:YP71_MYCTU (SWALL:Q50650) (355 aa) fasta scores: E(): 3.6e-12, 28.2% id in 234 aa. Note: Also similar to DIP2068 (375 aa) E(): 8.4e-62; 52.174% identity in 368 aa overlap NP_940398.1 Similar to Escherichia coli Hp2 or InsA SWALL:O87507 (EMBL:AF081284) (100 aa) fasta scores: E(): 8.6e-07, 31.95% id in 97 aa, and to Shigella flexneri TnpJ or S0170 or S0109 SWALL:Q9XCG9 (EMBL:AF141323) (100 aa) fasta scores: E(): 8.6e-07, 31.95% id in 97 aa, and to Shigella dysenteriae InsA SWALL:Q9LA21 (EMBL:AF153317) (100 aa) fasta scores: E(): 2.1e-06, 31.95% id in 97 aa NP_940403.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function NP_940404.1 Similar to many oxidoreductases e.g. Rhizobium meliloti oxidoreductase R01702 or SMC00274 SWALL:CAC46281 (EMBL:AL591788) (295 aa) fasta scores: E(): 7.6e-30, 41.4% id in 285 aa, and to Escherichia coli hypothetical oxidoreductase YgbJ or B2736 SWALL:YGBJ_ECOLI (SWALL:Q46888) (302 aa) fasta scores: E(): 2e-26, 36.08% id in 291 aa NP_940405.1 Similar to Synechocystis sp hypothetical 48.5 kDa protein SLR1342 SWALL:P74079 (EMBL:D90912) (445 aa) fasta scores: E(): 2.4e-39, 34.19% id in 462 aa NP_940406.1 Similar to Escherichia coli O157:H7 transcriptional regulator LldR or Z5031 or ECS4482 SWALL:BAB37905 (EMBL:AE005588) (258 aa) fasta scores: E(): 1.9e-14, 33.48% id in 224 aa, and to Pseudomonas aeruginosa transcriptional regulator GlcC or PA5356 SWALL:Q9HTK2 (EMBL:AE004947) (251 aa) fasta scores: E(): 1e-13, 32.36% id in 241 aa NP_940407.1 Similar to Streptomyces coelicolor insertion element IS110 hypothetical 43.6 kDa protein SC3C8.10 and SCC57A.30c and SCG2.18 and SC5E9.30 SWALL:YIS1_STRCO (SWALL:P19780) (405 aa) fasta scores: E(): 1.6e-52, 40.65% id in 396 aa, and to Shigella flexneri transposase for IS110 s0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.5e-47, 42.44% id in 384 aa NP_940408.1 Similar to Streptococcus pneumoniae hypothetical 20.7 kDa protein SWALL:Q9KK22 (EMBL:AF154034) (171 aa) fasta scores: E(): 3.2e-09, 33.54% id in 155 aa, and to Escherichia coli insertion element IS1397 hypothetical 20.1 kDa protein SWALL:YI9A_ECOLI (SWALL:Q47309) (173 aa) fasta scores: E(): 0.0075, 33.62% id in 113 aa NP_940409.1 Low similarity to Staphylococcus aureus (strain N315) Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein SdrC or SA0519 or SAV0561 SWALL:BAB56723 (EMBL:AP003131) (953 aa) fasta scores: E(): 4.5e-06, 28.57% id in 448 aa, and to Staphylococcus aureus SdrC protein SWALL:O86487 (EMBL:AJ005645) (947 aa) fasta scores: E(): 1.6e-05, 25% id in 804 aa. Note: There is no similarity to the C-terminal SD rich region of the database hits and contains a potential sortase anchor site (LAATG) upstream of the C-terminal region transmembrane domain NP_940410.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_940411.1 Similar to Mycobacterium tuberculosis CDC1551 fructose-bisphosphate aldolase MT0381 SWALL:AAK44602 (EMBL:AE006943) (376 aa) fasta scores: E(): 7.2e-55, 43.61% id in 376 aa, and to Corynebacterium glutamicum hypothetical protein in fda 5' region SWALL:Q99336 (EMBL:X17313) (304 aa) fasta scores: E(): 1.6e-37, 60.55% id in 289 aa NP_940412.1 Similar to although shoter in its N-terminal region than Mycobacterium tuberculosis CDC1551 SpoU rRNA methylase MT0393 SWALL:AAK44615 (EMBL:AE006944) (183 aa) fasta scores: E(): 6.2e-51, 74.41% id in 172 aa, and to Escherichia coli tRNA TrmH or SpoU or B3651 or Z5077 or ECS4526 SWALL:TRMH_ECOLI (SWALL:P19396) (229 aa) fasta scores: E(): 4.6e-07, 28.94% id in 152 aa NP_940413.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_940415.1 Similar to Streptomyces coelicolor thiosulfate sulfurtransferase SC9B10.21 SWALL:O50528 (EMBL:AL009204) (283 aa) fasta scores: E(): 1.8e-28, 35% id in 280 aa, and to Pseudomonas aeruginosa probable 3-mercaptopyruvate sulfurtransferase SseA or PA1292 SWALL:THTM_PSEAE (SWALL:Q9I452) (284 aa) fasta scores: E(): 2.4e-28, 36.07% id in 280 aa NP_940417.1 Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap NP_940420.1 Similar to Escherichia coli ClpB or HtpM or B2592 or Z3886 or ECS3455 SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 2.3e-133, 56.67% id in 847 aa, and to Corynebacterium glutamicum ClpB SW:CLPB_CORGL (P53532) (852 aa) fasta scores: E(): 0, 85.25% id in 841 aa NP_940421.1 Similar to the N-terminal portion of many from actinomycetes eg. Streptomyces coelicolor secreted protein SCE41.06c TR:Q9F2Q2 (EMBL:AL442120) (244 aa) fasta scores: E(): 7.5e-21, 65.74% id in 108 aa. Also full length similarity to others from actinomycetes eg. Streptomyces coelicolor membrane protein SC5C11.15 TR:Q9L157 (EMBL:AL158060) (121 aa) fasta scores: E(): 1.9e-14, 50.49% id in 101 aa NP_940422.1 Similar to Streptomyces coelicolor ABC transport system ATP-binding protein SCD10.29c TR:Q9K3U8 (EMBL:AL359988) (263 aa) fasta scores: E(): 8.8e-37, 49.6% id in 252 aa, and to Caulobacter crescentus ABC transporter, ATP-binding protein CC0838 TR:Q9A9X3 (EMBL:AE005760) (250 aa) fasta scores: E(): 2.6e-27, 42.25% id in 239 aa NP_940423.1 Similar to Streptomyces coelicolor integral membrane transport protein SCD10.28c TR:Q9K3U9 (EMBL:AL359988) (550 aa) fasta scores: E(): 6.2e-18, 25.27% id in 542 aa. Lies alongside a ABC transporter ATP-binding subunit NP_940424.1 Weakly similar to many eg. Pseudomonas aeruginosa sodium/glutamate symporter GltS or PA3176 TR:Q9HZ58 (EMBL:AE004741) (404 aa) fasta scores: E(): 2.2e-06, 23.83% id in 365 aa, and to Escherichia coli sodium/glutamate symport carrier protein GltS or GltC or B3653 SW:GLTS_ECOLI (P19933) (401 aa) fasta scores: E(): 0.097, 22.36% id in 398 aa NP_940425.1 Similar to Rhizobium loti MLL2462 protein TR:Q98IC8 (EMBL:AP002999) (352 aa) fasta scores: E(): 1.7e-36, 37.16% id in 339 aa NP_940426.1 Similar to Mycobacterium bovis 47 kDa protein Rv0385 or MT0398 or MTV036.20 TR:O86363 (EMBL:U73653) (390 aa) fasta scores: E(): 4.7e-29, 36.36% id in 352 aa, and to Acinetobacter calcoaceticus phenolhydroxylase component TR:Q43983 (EMBL:Z36909) (350 aa) fasta scores: E(): 2.2e-06, 25.61% id in 246 aa, and to Pseudomonas sp phenol hydroxylase P5 protein DmpP SW:DMPP_PSESP (P19734) (352 aa) fasta scores: E(): 8.3e-06, 24.3% id in 251 aa NP_940427.1 Similar to Mycobacterium leprae hydrolase ML2449 TR:Q9CB47 (EMBL:AL583925) (271 aa) fasta scores: E(): 4.8e-37, 47.84% id in 255 aa, and to Mus musculus Nit protein 2 or 1190017B19riK TR:Q9JHW2 (EMBL:AF284573) (276 aa) fasta scores: E(): 2.7e-17, 29.88% id in 251 aa NP_940428.1 Doubtful CDS. No significant database matches. No stong consensus RBS. Predicted by Frameplot NP_940430.1 Similar to Rhizobium meliloti alcohol dehydrogenase AdhA or RA0704 or SMA1296 SWALL:ADHA_RHIME (SWALL:O31186) (340 aa) fasta scores: E(): 1.4e-71, 55.09% id in 334 aa, and to Pseudomonas aeruginosa alcohol dehydrogenase AdhA or PA5427 SWALL:Q9HTD9 (EMBL:AE004955) (342 aa) fasta scores: E(): 1.5e-79, 58.99% id in 339 aa NP_940431.1 Similar to many eg. Acinetobacter spM-1. aldehyde dehydrogenase 1 Ald1 TR:Q9FDS1 (EMBL:AB042203) (503 aa) fasta scores: E(): 2.5e-143, 69.18% id in 503 aa, and to Alcaligenes eutrophus acetaldehyde dehydrogenase II AcoD SW:DHA2_ALCEU (P46368) (506 aa) fasta scores: E(): 1.8e-135, 66.39% id in 497 aa NP_940432.1 No significant database matches. Lies in a DNA region of unusually low G+C content. NP_940433.1 Similar to Streptomyces coelicolor heat shock protein HspR or SCH44.08c SW:HSPR_STRCO (P40183) (151 aa) fasta scores: E(): 5.4e-16, 52.59% id in 135 aa, and to Mycobacterium tuberculosis HspR or Rv0353 or MTCY13E10.13 TR:O06302 (EMBL:Z95324) (126 aa) fasta scores: E(): 6.6e-23, 66.66% id in 117 aa NP_940434.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_940435.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_940436.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_940437.1 Some similarity to integral membrane sensory proteins though DIP2121 does not appear to be a membrane protein. Similar to Rhodobacter capsulatus potential sensory protein TR:O68073 (EMBL:AF010496) (416 aa) fasta scores: E(): 1.6e-11, 27.93% id in 426 aa, and to Escherichia coli ORFI protein TR:Q56321 (EMBL:X61367) (525 aa) fasta scores: E(): 2.2e-09, 25.78% id in 446 aa, and to Escherichia coli aerotaxis receptor Aer or Air or B3072 SW:AER_ECOLI (P50466) (506 aa) fasta scores: E(): 1e-08, 25.29% id in 423 aa NP_940438.1 Similar to Streptomyces coelicolor integral membrane protein SCF6.09 TR:Q9RJL9 (EMBL:AL121849) (363 aa) fasta scores: E(): 3.1e-49, 44.27% id in 332 aa, and to Escherichia coli permease B2493 or Z3755 or ECS3355 SW:PERM_ECOLI (P77406) (353 aa) fasta scores: E(): 1.7e-18, 27.89% id in 337 aa NP_940439.1 Similar to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SW:INSK_ECOLI (P19769) (283 aa) fasta scores: E(): 1.4e-43, 44.86% id in 263 aa. Identical to DIP0434, DIP1517, DIP1526 and DIP1809 NP_940440.1 Similar to Streptococcus pneumoniae hypothetical 20.7 kDa protein TR:Q9KK22 (EMBL:AF154034) (171 aa) fasta scores: E(): 1.3e-08, 33.75% id in 157 aa, and to Yersinia pestis insertion element IS1661 DNA-binding protein YPO3931 TR:CAC93394 (EMBL:AJ414159) (171 aa) fasta scores: E(): 0.00044, 25.45% id in 165 aa. Identical to DIP0435, DIP1518, DIP1525 and DIP1808 NP_940441.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding protein SC9B5.22 TR:Q9ZBF8 (EMBL:AL035206) (222 aa) fasta scores: E(): 7.5e-19, 41.66% id in 216 aa, and to Escherichia coli nickel transport ATP-binding protein NikE or B3480 SW:NIKE_ECOLI (P33594) (268 aa) fasta scores: E(): 6.3e-17, 38.72% id in 204 aa NP_940442.1 Similar to Streptomyces coelicolor transport permease SC9B5.20 TR:Q9ZBG0 (EMBL:AL035206) (312 aa) fasta scores: E(): 4.4e-32, 45.27% id in 254 aa, and to Bacillus subtilis dipeptide transport system permease DppC or DciAC SW:DPPC_BACSU (P26904) (320 aa) fasta scores: E(): 4.3e-23, 37.19% id in 242 aa NP_940443.1 Similar to Streptomyces coelicolor transport permease SC9B5.19 TR:Q9ZBG1 (EMBL:AL035206) (334 aa) fasta scores: E(): 8.6e-44, 43.51% id in 324 aa, and to Bacillus subtilis oligopeptide transport system permease AppB SW:APPB_BACSU (P42062) (317 aa) fasta scores: E(): 6.2e-25, 28.61% id in 318 aa NP_940444.1 Similar to Streptomyces coelicolor substrate binding protein SC9B5.18 TR:Q9ZBG2 (EMBL:AL035206) (542 aa) fasta scores: E(): 2e-50, 33.14% id in 516 aa, and to Streptomyces lividans Xp55 protein SW:XP55_STRLI (P06109) (542 aa) fasta scores: E(): 1.7e-43, 32.16% id in 485 aa NP_940445.1 Similar to Mycobacterium tuberculosis phosphate permease Rv2281 or MT2339 or MTCY339.29C SW:YM81_MYCTU (Q50684) (552 aa) fasta scores: E(): 1.2e-121, 61% id in 518 aa NP_940446.1 Full length similarity to Streptococcus pneumoniae phosphoribosylformylglycinamidine synthase, SP0045 TR:AAK74234 (EMBL:AE007322) (1241 aa) fasta scores: E(): 7.8e-167, 47.73% id in 1259 aa. Second two thirds similar to many others e.g. Mycobacterium tuberculosis phosphoribosylformylglycinamidine synthase II PurL or Rv0803 or MT0823 or MTCY07H7A.06c SW:PURL_MYCTU (P54876) (754 aa) fasta scores: E(): 8.3e-22, 26.35% id in 740 aa NP_940447.1 Catalyzes hydrolysis of n-ribosyl-purine into a purine and d-ribose NP_940448.1 Weakly similar to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SW:ADRO_RAT (P56522) (494 aa) fasta scores: E(): 0.002, 28.3% id in 159 aa, and to Streptomyces coelicolor ferredoxin/ferredoxin-NADP reductase SCF15.02 TR:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 0.048, 29% id in 131 aa NP_940449.1 Similar to many eg. Mycobacterium tuberculosis hypothetical 95.5 kDa protein Rv0338c or MT0352 or MTCY279.05C TR:O33268 (EMBL:Z97991) (882 aa) fasta scores: E(): 2.4e-55, 43.1% id in 877 aa. N-terminal region appears to be has possible membrane-spanning hydrophobic regions while the C-terminal region is rich in proline and alanine. NP_940450.1 N-terminus similar to those from other actinomycetes eg. Saccharopolyspora erythraea Orf122 protein TR:Q54106 (EMBL:X92556) (121 aa) fasta scores: E(): 0.0076, 31.15% id in 138 aa, and to Streptomyces coelicolor hypothetical 30.8 kDa protein SCE6.30c TR:Q9KZR0 (EMBL:AL353832) (277 aa) fasta scores: E(): 0.02, 36.76% id in 68 aa NP_940451.1 Similar to Neisseria meningitidis zinc-binding alcohol dehydrogenase NMA0808 TR:Q9JVJ8 (EMBL:AL162754) (354 aa) fasta scores: E(): 1.1e-85, 64.62% id in 359 aa, and to Bacillus cereus acetylacetoin reductase AacR TR:BAB60856 (EMBL:AB063194) (349 aa) fasta scores: E(): 5.6e-47, 42.25% id in 355 aa, and to Pseudomonas putida 2,3-butanediol dehydrogenase Adh TR:Q59696 (EMBL:L35343) (362 aa) fasta scores: E(): 6.6e-40, 37.63% id in 364 aa NP_940452.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor NP_940453.1 Similar to Streptomyces coelicolor membrane protein SCQ11.10c TR:Q9X9U1 (EMBL:AL096823) (513 aa) fasta scores: E(): 2.1e-35, 37.59% id in 383 aa, and to Pseudomonas aeruginosa sensor protein GlpS or pa1977 SW:GLPS_PSEAE (P29370) (287 aa) fasta scores: E(): 2.5, 29.41% id in 238 aa NP_940454.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_940456.1 Weakly similar to Lactococcus lactis unknown protein YldA or ll1118 TR:Q9CGH8 (EMBL:AE006344) (209 aa) fasta scores: E(): 0.092, 24% id in 175 aa NP_940457.1 Similar to Streptomyces coelicolor UDP-glucose 6-dehydrogenase SCBAC19G2.07 TR:CAC44517 (EMBL:AL596138) (447 aa) fasta scores: E(): 2.8e-33, 40.75% id in 422 aa, and to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or pa2022 SW:UDG_PSEAE (O86422) (453 aa) fasta scores: E(): 1.9e-26, 39.66% id in 358 aa, and to Rhizobium meliloti UDP-glucose 6-dehydrogenase Rkpk or r01082 or smc02641 SW:UDG_RHIME (O54068) (437 aa) fasta scores: E(): 8.9e-26, 37.71% id in 411 aa, and to Escherichia coli UDP-glucose 6-dehydrogenase KfiD SW:UDG5_ECOLI (Q47329) (392 aa) fasta scores: E(): 1.5e-24, 32.81% id in 323 aa NP_940458.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_940459.1 Weakly similar to Bacillus subtilis hypothetical YxlG TR:P94375 (EMBL:D83026) (259 aa) fasta scores: E(): 1.2, 24.72% id in 182 aa, and to Rhizobium loti Mll2378 protein TR:Q98IJ2 (EMBL:AP002999) (339 aa) fasta scores: E(): 1.3, 26.98% id in 252 aa. Lies alongside a ABC transporter ATP-binding subunit. NP_940460.1 Similar to many eg. Bacillus licheniformis bacitracin transport ATP-binding protein BcrA SW:BCRA_BACLI (P42332) (306 aa) fasta scores: E(): 2.7e-22, 35.01% id in 277 aa NP_940463.1 Similar to Streptomyces coelicolor conserved hypothetical protein SCE20.33c TR:Q9RD92 (EMBL:AL136058) (125 aa) fasta scores: E(): 3e-12, 44.79% id in 96 aa, and to Caulobacter crescentus hypothetical protein Cc3408 TR:Q9A2Z8 (EMBL:AE006001) (108 aa) fasta scores: E(): 2.9e-10, 42.26% id in 97 aa NP_940465.1 Similar to Bacteriophage phi-105 holin TR:Q38456 (EMBL:L35561) (124 aa) fasta scores: E(): 5.4e-14, 41.22% id in 114 aa, and to Escherichia coli O157:H7 holin protein of prophage cp-933c Z1852 or ECS1595 TR:AAG55949 (EMBL:AE005328) (129 aa) fasta scores: E(): 1.7e-07, 40.77% id in 103 aa NP_940466.1 Similar to Xylella fastidiosa phage-related protein XF0684 TR:Q9PFH4 (EMBL:AE003912) (503 aa) fasta scores: E(): 1.8e-13, 56.52% id in 92 aa, and to Lactobacillus casei bacteriophage A2 Antirepressor Ant TR:O64368 (EMBL:AJ251789) (160 aa) fasta scores: E(): 2.9e-08, 36.69% id in 139 aa, and to Bacteriophage r1t integrase, repressor protein TR:Q38091 (EMBL:U38906) (265 aa) fasta scores: E(): 2.3e-06, 36.98% id in 219 aa NP_940467.1 Similar to Pasteurella multocida hypothetical protein Pm1783 TR:Q9CK51 (EMBL:AE006215) (316 aa) fasta scores: E(): 1.4e-26, 32.226% id in 301 aa, and to Staphylococcus aureus subspaureus Mu50. hypothetical 38.5 kDa protein Sav0801 TR:BAB56963 (EMBL:AP003360) (322 aa) fasta scores: E(): 2.7e-07, 22.876% id in 306 aa NP_940468.1 Similar to Yersinia pestis YbtP TR:Q9ZG01 (EMBL:AF091251) (600 aa) fasta scores: E(): 5e-46, 31.046% id in 583 aa, and to Escherichia coli, and probable transport ATP-binding protein MsbA or B0914 or Z1260 or ECS0997 SW:MSBA_ECOLI (P27299) (582 aa) fasta scores: E(): 1.6e-42, 30.969% id in 578 aa NP_940469.1 Similar to Yersinia enterocolitica lipoprotein inner membrane ABC-transporter, Irp6 TR:Q9X9I5 (EMBL:AJ132668) (600 aa) fasta scores: E(): 2.5e-43, 34.286% id in 560 aa, and to Streptomyces natalensis PimB protein TR:Q9EW97 (EMBL:AJ278573) (626 aa) fasta scores: E(): 3e-37, 32.519% id in 532 aa NP_940470.1 Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa NP_940471.1 Similar to Stigmatella aurantiaca myxothiazol synthase MtaC TR:Q9RFK9 (EMBL:AF188287) (1290 aa) fasta scores: E(): 1.7e-86, 35.694% id in 1073 aa, and to Polyangium cellulosum epothilone biosynthase EpoB TR:Q9KIZ9 (EMBL:AF217189) (1410 aa) fasta scores: E(): 1.8e-81, 35.385% id in 975 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF or PA4225 TR:Q9HWG4 (EMBL:AE004839) (1809 aa) fasta scores: E(): 1.9e-81, 37.017% id in 932 aa NP_940472.1 Similar to Streptomyces coelicolor secreted solute-binding protein SC4C2.12 TR:Q9EWQ0 (EMBL:AL450432) (528 aa) fasta scores: E(): 4.7e-23, 29.923% id in 518 aa, and to Rhizobium loti ABC transporter, binding protein MLL5127 TR:Q98CJ3 (EMBL:AP003005) (528 aa) fasta scores: E(): 1.4e-22, 27.921% id in 505 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRDFLK) at the N-terminal region NP_940473.1 Similar to Streptomyces coelicolor metal transport integral membrane protein SC4C2.13 TR:Q9EWP9 (EMBL:AL450432) (316 aa) fasta scores: E(): 3.2e-30, 39.344% id in 305 aa, and to Rhizobium meliloti ABC transporter permease SMA0300 TR:AAK64819 (EMBL:AE007209) (317 aa) fasta scores: E(): 2.1e-20, 27.303% id in 304 aa NP_940474.1 Similar to Streptomyces coelicolor transport system integral membrane protein SC4C2.14 TR:Q9EWP8 (EMBL:AL450432) (284 aa) fasta scores: E(): 4.4e-17, 32.567% id in 261 aa, and to Rhizobium loti ABC transporter, permease MLL7032 TR:Q987J0 (EMBL:AP003010) (283 aa) fasta scores: E(): 1.9e-14, 30.859% id in 256 aa NP_940475.1 Similar to Rhizobium meliloti ABC transporter SMA0298 TR:AAK64817 (EMBL:AE007209) (604 aa) fasta scores: E(): 1.5e-15, 27.536% id in 552 aa, and to Streptomyces coelicolor peptide transport ATP-binding protein SC9F2.04 TR:Q9Z531 (EMBL:AL035559) (359 aa) fasta scores: E(): 3.4e-15, 39.409% id in 203 aa NP_940476.1 Similar to Amycolatopsis orientalis integral membrane sugar transporter CZA382.17c TR:Q9XBD4 (EMBL:AL078635) (444 aa) fasta scores: E(): 3.8e-43, 37.264% id in 424 aa, and to Burkholderia cepacia MopB protein TR:Q45082 (EMBL:U29532) (449 aa) fasta scores: E(): 1.2e-40, 35.885% id in 418 aa NP_940477.1 Similar to fragment of Mycobacterium tuberculosis 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE or Rv1133c or MT1165 or MTC22G8.22 SW:METE_MYCTU (O06584) (759 aa) fasta scores: E(): 2.5e-06, 70.732% id in 41 aa, and to Streptomyces griseus subspgriseus. 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase- like protein TR:Q9KHC5 (EMBL:AF263012) (774 aa) fasta scores: E(): 4.1e-06, 77.778% id in 36 aa, and to Saccharomyces cerevisiae 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Met6 or YER091c SW:METE_YEAST (P05694) (766 aa) fasta scores: E(): 7.8e-05, 71.429% id in 35 aa NP_940478.1 Similar to Streptomyces coelicolor membrane transport protein SCC75A.30c TR:Q9RKP4 (EMBL:AL133220) (428 aa) fasta scores: E(): 5.2e-40, 36.935% id in 398 aa, and to Escherichia coli bicyclomycin resistance protein Bcr or BicA or BicR or Sur or SuxA or b2182 SW:BCR_ECOLI (P28246) (396 aa) fasta scores: E(): 3.4e-31, 30.548% id in 383 aa NP_940480.1 Similar to Bacillus subtilis hypothetical 27.6 kDa protein in fnr-narG intergenic region YwiC SW:YWIC_BACSU (P46909) (239 aa) fasta scores: E(): 5e-08, 28.571% id in 259 aa, and to Haemophilus influenzae hypothetical protein HI1626 SW:YG26_HAEIN (P44278) (238 aa) fasta scores: E(): 3.6e-06, 25.758% id in 264 aa NP_940482.1 Similar to Mycobacterium leprae secreted glycosyl hydrolase ML2569 or MLCB1883.14 TR:O69499 (EMBL:AL022486) (387 aa) fasta scores: E(): 3e-40, 42.33% id in 385 aa, and to Vibrio furnissii beta-hexosaminidase NagZ or Exo II SW:NAGZ_VIBFU (P96157) (329 aa) fasta scores: E(): 9e-13, 30.94% id in 265 aa. Note: Contains a twin-arginine translocation (TAT) system recognition motif (RRVFTP) at the N-terminal region NP_940483.1 Similar to Mycobacterium tuberculosis secreted protein Rv0236.1 precursor or Rv0236A or MT0250 SW:Y23A_MYCTU (P58240) (57 aa) fasta scores: E(): 0.39, 32.72% id in 55 aa NP_940484.1 Similar to Mycobacterium leprae possible integral membrane protein ML2570 TR:Q9CD19 (EMBL:AL583926) (1405 aa) fasta scores: E(): 2.5e-17, 37.3% id in 823 aa, and to Mycobacterium tuberculosis hypothetical 146.3 kDa protein Rv0236c or MT0247 or MTV034.01c or MTV034.02c or MTCY08D5.32c TR:AAK44467 (EMBL:Z92669) (1400 aa) fasta scores: E(): 7.4e-17, 38.32% id in 822 aa. ORF overlaps with convergent downstream ORF NP_940485.1 Similar to Mycobacterium tuberculosis hypothetical 43.3 kDa protein Rv0228 or MT0238 or MTCY08D5.23 TR:P96410 (EMBL:Z92669) (407 aa) fasta scores: E(): 1.2e-31, 38.84% id in 381 aa, and to Streptomyces thermotolerans macrolide antibiotics 3-O-acyltransferase AcyA TR:Q56074 (EMBL:D30759) (389 aa) fasta scores: E(): 6e-07, 30.43% id in 322 aa, and to Streptomyces mycarofaciens acyltransferase MdmB SW:MDMB_STRMY (Q00718) (387 aa) fasta scores: E(): 8e-07, 29.14% id in 398 aa. ORF overlaps with convergent downstream ORF. NP_940486.1 Similar to Mycobacterium leprae integral membrane protein Ml2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 8.6e-14, 27.79% id in 367 aa NP_940487.1 Similar to Mycobacterium tuberculosis hypothetical 59.1 kDa protein Rv0226c or MTCY08D5.21c TR:P96408 (EMBL:Z92669) (576 aa) fasta scores: E(): 6e-08, 30% id in 530 aa. ORF overlaps with convergent downstream ORF NP_940488.1 Similar to Mycobacterium tuberculosis hypothetical 42.1 kDa protein Rv0225 or MTCY08D5.20 TR:P96407 (EMBL:Z92669) (384 aa) fasta scores: E(): 3.5e-62, 51.48% id in 371 aa. ORF overlaps with convergent downstream ORF NP_940489.1 Similar to Mycobacterium tuberculosis hypothetical 27.5 kDa protein Rv0224c or MTCY08D5.19c TR:P96406 (EMBL:Z92669) (254 aa) fasta scores: E(): 2.9e-56, 63.41% id in 246 aa, and to Streptomyces coelicolor methyltransferase SCC53.08c TR:Q9KXK3 (EMBL:AL357591) (244 aa) fasta scores: E(): 7.1e-06, 32.94% id in 173 aa NP_940490.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP NP_940491.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_940492.1 Similar to Mycobacterium tuberculosis hypothetical 26.2 kDa protein Rv0207c or MT0217 or MTCY08D5.02c TR:AAK44438 (EMBL:Z92669) (244 aa) fasta scores: E(): 8.6e-51, 64.03% id in 203 aa NP_940493.1 Similar to Mycobacterium tuberculosis membrane protein MmpL3 or Rv0206c or MT0216 or MTV033.14c or MTCY08D5.01c SW:MML3_MYCTU (O53657) (944 aa) fasta scores: E(): 2.1e-45, 44.69% id in 754 aa, and to Streptomyces coelicolor integral membrane protein SCC24.25 TR:Q9L092 (EMBL:AL163003) (743 aa) fasta scores: E(): 4.6e-42, 34.79% id in 750 aa NP_940494.1 Similar to Mycobacterium tuberculosis hypothetical 44.0 kDa protein Rv0204c or MT0214 or MTV033.12c TR:O53655 (EMBL:AL021928) (412 aa) fasta scores: E(): 3.4e-15, 30.24% id in 324 aa NP_940495.1 Similar to Mycobacterium tuberculosis hypothetical 12.6 kDa protein Rv0401 or MTCY04D9.14 TR:P95210 (EMBL:Z84725) (123 aa) fasta scores: E(): 5.3e-11, 36.6% id in 112 aa NP_940496.1 Similar to Streptomyces coelicolor propionyl-CoA carboxylase complex B subunit PccB TR:Q9X4K7 (EMBL:AF113605) (530 aa) fasta scores: E(): 8.2e-102, 52.29% id in 522 aa, and to Mycobacterium tuberculosis propionyl-CoA carboxylase AccD4 or Rv3799c or MTV026.04c TR:O53578 (EMBL:AL022076) (518 aa) fasta scores: E(): 2.2e-106, 54.51% id in 510 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 1.2e-88, 51.88% id in 530 aa NP_940497.1 Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa NP_940498.1 Activates fatty acids by binding to coenzyme A NP_940499.1 Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa NP_940500.1 N-terminal region presents very low similarity to the following: Corynebacterium equii virulence associated protein VapA TR:Q9EUL9 (EMBL:AF116907) (189 aa) fasta scores: E(): 0.7, 27.92% id in 111 aa, and to Staphylococcus aureus hypothetical protein SAV2001 TR:BAB58163 (EMBL:AP003364) (154 aa) fasta scores: E(): 0.99, 26.61% id in 124 aa, and to Corynebacterium equii virulence-associated 15-17-kDa antigen VapA TR:Q57470 (EMBL:D21236) (189 aa) fasta scores: E(): 4.1, 27.02% id in 111 aa NP_940501.1 Similar to Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.8e-147, 57.51% id in 659 aa, and similar to but longer than Mycobacterium intracellulare antigen 85-B precursor FbpB SW:A85B_MYCIT (Q49575) (330 aa) fasta scores: E(): 1.8e-29, 37.18% id in 320 aa NP_940502.1 Similar to Mycobacterium avium antigen 85-C precursor FbpC SW:A85C_MYCAV (O52972) (352 aa) fasta scores: E(): 3.7e-29, 34.32% id in 335 aa, and similar to but shorter than Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.5e-28, 35.69% id in 297 aa NP_940503.1 Similar to Mycobacterium tuberculosis membrane protein Rv3805c or MT3912 or MTV026.10c TR:O53582 (EMBL:AL022076) (627 aa) fasta scores: E(): 4.1e-25, 36.36% id in 594 aa NP_940504.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate NP_940505.1 Similar to Mycobacterium tuberculosis hypothetical 17.2 kDa protein Rv3807c or MTV026.12 TR:O53584 (EMBL:AL022076) (165 aa) fasta scores: E(): 7.9e-29, 52.56% id in 156 aa, and to Streptomyces coelicolor integral membrane protein SC5G8.11 TR:Q9KZA3 (EMBL:AL353872) (169 aa) fasta scores: E(): 9.1e-17, 46.04% id in 139 aa NP_940506.1 Similar proteins from other actinomycetes eg. Mycobacterium tuberculosis hypothetical 71.5 kDa protein Rv3808c or MT3915 or MTV026.13c TR:O53585 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.3e-88, 54.79% id in 657 aa NP_940507.1 Similar to Corynebacterium ammoniagenes Orf2 protein TR:Q9RHY7 (EMBL:AB003155) (163 aa) fasta scores: E(): 6.5e-14, 39.21% id in 153 aa, and to Escherichia coli hypothetical protein YbjG or B0841 SW:YBJG_ECOLI (P75806) (198 aa) fasta scores: E(): 1.9e-06, 32.69% id in 156 aa NP_940508.1 Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SW:DHAB_BACSU (P71016) (490 aa) fasta scores: E(): 2e-73, 54.63% id in 496 aa, and to Streptomyces coelicolor betaine aldehyde dehydrogenase GbsA TR:Q9K3J2 (EMBL:AL389898) (509 aa) fasta scores: E(): 3.2e-88, 55.75% id in 504 aa NP_940509.1 Similar to Escherichia coli high-affinity choline transport protein BetT or B0314 or Z0401 or ECS0360 SW:BETT_ECOLI (P17447) (677 aa) fasta scores: E(): 1.9e-118, 53.14% id in 668 aa, and to Erwinia amylovora high-affinity choline transport protein BetT TR:Q9F806 (EMBL:AF264948) (676 aa) fasta scores: E(): 2.5e-116, 51.98% id in 681 aa NP_940510.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine NP_940511.1 Similar to Escherichia coli UDP-galactopyranose mutase Glf or B2036 SW:GLF_ECOLI (P37747) (367 aa) fasta scores: E(): 5.4e-48, 45.35% id in 377 aa, and to Mycobacterium tuberculosis UDP-galactopyranose mutase Glf or Rv3809c or MTV026.14 TR:O06934 (EMBL:U96128) (399 aa) fasta scores: E(): 1.3e-121, 76.09% id in 389 aa NP_940512.1 Similar to Mycobacterium tuberculosis hypothetical 23.9 kDa protein Rv0836c or MT0857 or MTV043.29c TR:O53848 (EMBL:AL022004) (217 aa) fasta scores: E(): 4.3e-13, 37.98% id in 129 aa NP_940513.1 Similar to Mycobacterium tuberculosis hypothetical 36.9 kDa protein Rv0837c or MTV043.30c TR:O53849 (EMBL:AL022004) (342 aa) fasta scores: E(): 7.7e-14, 30.38% id in 260 aa NP_940515.1 Similar to Mycobacterium tuberculosis Csp or Rv3811 or MT3918 or MTV026.16 TR:O86334 (EMBL:Z97188) (539 aa) fasta scores: E(): 6.2e-33, 41.84% id in 411 aa, and to Streptomyces coelicolor secreted protein SCE34.21c TR:Q9KZK5 (EMBL:AL353862) (416 aa) fasta scores: E(): 5.6e-20, 28.74% id in 421 aa. Contains a proline/alanine rich region at residues 398-44, no present in homologues NP_940516.1 Similar to Escherichia coli hypothetical protein YgcI precursor or B2757 SW:YGCI_ECOLI (Q46898) (224 aa) fasta scores: E(): 0.02, 26.816% id in 179 aa NP_940517.1 Similar to Escherichia coli O157:H7 hypothetical 38.4 kDa protein ECS3612 TR:BAB37035 (EMBL:AP002562) (351 aa) fasta scores: E(): 8.7e-11, 33.333% id in 306 aa NP_940520.1 Similar to Escherichia coli hypothetical 22.3 kDa protein in iap-cysH intergenic region YgcH or B2756 SW:YGCH_ECOLI (Q46897) (199 aa) fasta scores: E(): 0.042, 24.873% id in 197 aa NP_940521.1 Similar to Escherichia coli hypothetical 100.5 kDa protein in iap-cysH intergenic region YgcB or B2761 SW:YGCB_ECOLI (P38036) (888 aa) fasta scores: E(): 1.1e-28, 28.827% id in 784 aa NP_940522.1 Similar to Escherichia coli hypothetical 33.2 kDa protein in iap-cysH intergenic region YgbT or B2755 SW:YGBT_ECOLI (Q46896) (305 aa) fasta scores: E(): 6.7e-17, 29.119% id in 261 aa NP_940523.1 Similar to Escherichia coli hypothetical 10.5 kDa protein in iap-cysH intergenic region YgbF or B2754 SW:YGBF_ECOLI (P45956) (94 aa) fasta scores: E(): 0.0075, 26.667% id in 90 aa NP_940524.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_940526.1 Similar to Mycobacteriophage TM4 gp6 TR:Q9ZX71 (EMBL:AF068845) (509 aa) fasta scores: E(): 1.4e-05, 32.903% id in 155 aa NP_940527.1 Some similarity to San Miguel sea lion virus RNA dependent RNA polymerase 3d TR:O09787 (EMBL:U52090) (149 aa) fasta scores: E(): 6.6, 31.776% id in 107 aa NP_940530.1 No significant database matches. Note: Contains a potential sortase anchor site (LGNTG) upstream of the C-terminal region transmembrane domain NP_940531.1 Similar to Actinomyces naeslundii fimbriae-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 2.3e-33, 42.500% id in 280 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.0034, 26.115% id in 157 aa NP_940532.1 Similar to Actinomyces naeslundii fimbria-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 3.2e-52, 51.254% id in 279 aa, and to Bifidobacterium longum NCC2705 sortase-like protein BL0676 SWALL:AAN24497 (EMBL:AE014690) (328 aa) fasta scores: E(): 3.6e-28, 34.02% id in 291 aa, and to Staphylococcus aureus subsp aureus Mu50 sortase SrtA TR:BAB58690 (EMBL:AP003365) (206 aa) fasta scores: E(): 0.027, 29.371% id in 143 aa NP_940533.1 Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 1e-30, 38.276% id in 580 aa, and to Actinomyces viscosus fimbrial subunit type 1 precursor SW:FM1_ACTVI (P18477) (533 aa) fasta scores: E(): 7.4e-12, 29.856% id in 556 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain NP_940534.1 Similar to Actinomyces naeslundii hypothetical 103.4 kDa protein TR:Q9EV17 (EMBL:AJ401093) (976 aa) fasta scores: E(): 0.0003, 29.146% id in 597 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain NP_940538.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_940539.1 Similar to Bacillus subtilis glycerol uptake facilitator protein GlpF SW:GLPF_BACSU (P18156) (274 aa) fasta scores: E(): 2.1e-23, 45.83% id in 240 aa NP_940540.1 Similar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa NP_940541.1 Similar to Mycobacterium tuberculosis acyltransferase Rv3816c or MTCY409.14 TR:O07807 (EMBL:Z97188) (259 aa) fasta scores: E(): 2.5e-34, 47.6% id in 250 aa, and to Brassica napus lysophosphatidic acid acyltransferase Act2 TR:Q9LLY4 (EMBL:AF111161) (344 aa) fasta scores: E(): 4.3e-06, 29.05% id in 148 aa NP_940542.1 Similar to Mycobacterium tuberculosis hypothetical 28.5 kDa protein Rv3813c or MTCY409.17 TR:O07810 (EMBL:Z97188) (273 aa) fasta scores: E(): 4.2e-35, 41.69% id in 271 aa, and to Streptomyces coelicolor hypothetical 32.5 kDa protein SCD78.17c TR:Q9ZBY2 (EMBL:AL034355) (305 aa) fasta scores: E(): 2.3e-19, 34.29% id in 277 aa NP_940543.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_940544.1 Similar to Streptomyces coelicolor GntR-family transcriptional regulator SC7E4.28c TR:Q9K492 (EMBL:AL359214) (254 aa) fasta scores: E(): 7.3e-21, 34.82% id in 224 aa, and to Escherichia coli fatty acyl responsive regulator FarR or G30 or B0730 SW:FARR_ECOLI (P13669) (240 aa) fasta scores: E(): 6.4e-14, 30.93% id in 236 aa NP_940545.1 Similar to, but shorter than, Mycobacterium tuberculosis hypothetical 47.0 kDa protein Rv3835 or MTCY01A6.34c TR:P96243 (EMBL:Z83864) (449 aa) fasta scores: E(): 6.4e-31, 34.83% id in 310 aa NP_940546.1 Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv3836 or MTCY01A6.33c TR:P96242 (EMBL:Z83864) (137 aa) fasta scores: E(): 2.5e-18, 47.78% id in 113 aa, and to Streptomyces coelicolor hypothetical 13.1 kDa protein SCD25.30 TR:Q9RKJ2 (EMBL:AL118514) (116 aa) fasta scores: E(): 5.9e-16, 46.08% id in 115 aa NP_940547.1 Similar to Mycoplasma fermentans similar to unrecognized orf in the mycobacterium tuberculosis genome sequence TR:Q9RFP6 (EMBL:AF179376) (373 aa) fasta scores: E(): 1.3e-25, 28.99% id in 369 aa, and to Mycobacterium tuberculosis hypothetical 48.1 kDa protein Rv3179 or MT3270 or MTV014.23 TR:O53329 (EMBL:AL021646) (429 aa) fasta scores: E(): 4e-15, 25.53% id in 423 aa NP_940548.1 Similar to Mycobacterium leprae phosphoglycerate mutase ML0079 TR:Q9CDC3 (EMBL:AL583917) (231 aa) fasta scores: E(): 4e-11, 33.64% id in 214 aa, and to Schizosaccharomyces pombe phosphoglycerate mutase Gpm1 or SPAC26F1.06 SW:PMGY_SCHPO (P36623) (211 aa) fasta scores: E(): 0.28, 24.4% id in 209 aa NP_940549.2 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis NP_940550.1 Similar to Rhodococcus sp enantiomerase-selective amidase AmdA TR:Q53116 (EMBL:M74531) (462 aa) fasta scores: E(): 6.2e-15, 30.19% id in 414 aa, and to Mycobacterium smegmatis nicotinamidase/pyrazinamidase PzaA TR:Q9ZHK8 (EMBL:AF058285) (468 aa) fasta scores: E(): 6.4e-14, 30.55% id in 360 aa, and to Rhodococcus erythropolis amidase AmdA SW:AMID_RHOER (P22984) (520 aa) fasta scores: E(): 2.8e-11, 33.61% id in 238 aa NP_940551.1 Similar to Streptomyces coelicolor integral membrane protein SC10A9.14c TR:Q9AK90 (EMBL:AL583943) (275 aa) fasta scores: E(): 1.6e-17, 41.12% id in 248 aa NP_940552.1 Similar to Pseudomonas aeruginosa nitric-oxide reductase subunit B NorB or PA0524 SW:NORB_PSEAE (Q59647) (466 aa) fasta scores: E(): 4e-19, 28.54% id in 494 aa, and to Pseudomonas stutzeri nitric-oxide reductase subunit B NorB SW:NORB_PSEST (P98008) (473 aa) fasta scores: E(): 3.3e-17, 27.18% id in 493 aa NP_940553.1 Region similar to many eg. Streptomyces coelicolor membrane protein SCBAC19G2.03c TR:CAC44513 (EMBL:AL596138) (397 aa) fasta scores: E(): 4.6e-19, 36.91% id in 409 aa, and to Staphylococcus aureus (strain N315), and SA2103 protein or SAV2310 TR:BAB58472 (EMBL:AP003136) (315 aa) fasta scores: E(): 4.5e-13, 31.07% id in 280 aa NP_940554.1 Similar to Vibrio cholerae sodium/alanine symporter Vc0784 TR:Q9KTV3 (EMBL:AE004164) (516 aa) fasta scores: E(): 1.7e-83, 47.34% id in 509 aa, and to Bacillus PS3 sodium/proton-dependent alanine carrier protein Acp SW:ALCP_BACP3 (P30145) (445 aa) fasta scores: E(): 3.9e-58, 46.25% id in 454 aa NP_940555.1 Similar to Bacillus subtilis hypothetical 72.2 kDa protein YrhL TR:O05402 (EMBL:U93874) (634 aa) fasta scores: E(): 5.9e-41, 31.37% id in 631 aa, and to Streptomyces coelicolor possible integral membrane protein SC8G12.07c TR:Q9KYZ8 (EMBL:AL355753) (418 aa) fasta scores: E(): 2.5e-32, 37.7% id in 419 aa NP_940556.1 Similar to Streptomyces coelicolor hypothetical 34.5 kDa protein SCBAC25E3.11c TR:CAC44698 (EMBL:AL596251) (321 aa) fasta scores: E(): 1.1e-27, 36.17% id in 293 aa NP_940557.1 Similar to Mycobacterium tuberculosis hypothetical 29.9 kDa protein GlpQ1 or Rv3842c or MT3950 or MTCY01A6.27 TR:P96236 (EMBL:Z83864) (274 aa) fasta scores: E(): 1e-08, 36.84% id in 247 aa, and to Streptomyces coelicolor phosphodiesterase 2SCG4.06 TR:Q9K3Q8 (EMBL:AL360034) (227 aa) fasta scores: E(): 1.2e-08, 28.5% id in 228 aa NP_940558.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH NP_940559.1 Similar to many eg. Mycobacterium tuberculosis hypothetical 25.9 kDa protein Rv1593c or MT1629 or MTCY336.11 TR:O06597 (EMBL:Z95586) (236 aa) fasta scores: E(): 1.2e-20, 37.28% id in 228 aa. Note possible alternative translational start site NP_940560.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_940561.1 Member of a large family of including Sulfolobus solfataricus aspartate oxidase NadB or SSO0997 TR:Q97ZC5 (EMBL:AE006719) (487 aa) fasta scores: E(): 1.4e-18, 36.79% id in 405 aa, and to Streptomyces coelicolor L-aspartate oxidase SCE94.33c TR:Q9X8N8 (EMBL:AL049628) (580 aa) fasta scores: E(): 2.1e-15, 39.6% id in 409 aa NP_940562.1 Similar to Mycobacterium tuberculosis nicotinate-nucleotide pyrophosphorylase [carboxylating] NadC or Rv1596 or MT1632 or MTCY336.08c SWALL:NADC_MYCTU (SWALL:O06594) (285 aa) fasta scores: E(): 2.1e-43, 51.09% id in 274 aa, and to Salmonella typhimurium nicotinate-nucleotide pyrophosphorylase [carboxylating] NadC or STM0145 SWALL:NADC_SALTY (SWALL:P30012) (296 aa) fasta scores: E(): 1.6e-34, 41.17% id in 272 aa NP_940563.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_940564.1 Similar to Corynebacterium melassecola manganese superoxide dismutase SodA SWALL:BAB62412 (EMBL:AF236111) (200 aa) fasta scores: E(): 1.7e-67, 84.26% id in 197 aa. Previously described as Corynebacterium diphtheriae superoxide dismutase [Mn] SodA or Sod SWALL:SODM_CORDI (SWALL:P42821) (162 aa) fasta scores: E(): 1.5e-62, 97.56% id in 164 aa (note difference in translational start) NP_940565.1 Similar to Neisseria meningitidis oxidoreductase NMA0666 SWALL:Q9JVV3 (EMBL:AL162753) (188 aa) fasta scores: E(): 5.4e-42, 62.7% id in 185 aa, and to Pseudomonas putida chromate reductase ChrR SWALL:AAK56853 (EMBL:AF375642) (186 aa) fasta scores: E(): 9.1e-28, 45.19% id in 177 aa, and to Arabidopsis thaliana NADPH:quinone oxidoreductase Nqr SWALL:Q9XFI5 (EMBL:AF145234) (196 aa) fasta scores: E(): 1.7e-11, 36.7% id in 158 aa NP_940566.1 Similar to Mycobacterium tuberculosis membrane protein Rv2181 or MTV021.14 SWALL:O53515 (EMBL:AL021957) (427 aa) fasta scores: E(): 1.3e-33, 34.86% id in 370 aa NP_940567.1 Similar to Mycobacterium tuberculosis hypothetical 123.1 kDa protein Rv1251c or MT1290 or MTV006.23c SWALL:O50466 (EMBL:AL021006) (1139 aa) fasta scores: E(): 1.6, 26.47% id in 544 aa NP_940568.1 Similar to Mycobacterium tuberculosis hypothetical 23.8 kDa protein Rv3850 or MTCY01A6.18C SWALL:P96227 (EMBL:Z83864) (218 aa) fasta scores: E(): 7.9e-15, 34.1% id in 217 aa NP_940569.1 Similar to Streptomyces coelicolor Lsr2-like protein SCD25.12c SWALL:Q9RKK8 (EMBL:AL118514) (105 aa) fasta scores: E(): 1.1e-08, 39.04% id in 105 aa, and to Mycobacterium leprae Lsr2 protein precursor or ML0234 SWALL:LSR2_MYCLE (SWALL:P24094) (112 aa) fasta scores: E(): 2.4, 26.95% id in 115 aa NP_940570.1 Similar to Streptomyces coelicolor two component system DNA binding response regulator SC10A9.12 SWALL:Q9AK92 (EMBL:AL583943) (211 aa) fasta scores: E(): 7.7e-38, 59.24% id in 211 aa, and to Corynebacterium diphtheriae response regulator ChrA (DIP2327) SWALL:Q9RPE9 (EMBL:AF161327) (199 aa) fasta scores: E(): 2.1e-21, 49.76% id in 209 aa NP_940571.1 Similar to Streptomyces coelicolor two component system histidine kinase SC10A9.11 SWALL:Q9AK93 (EMBL:AL583943) (404 aa) fasta scores: E(): 7.7e-36, 37.15% id in 401 aa, and to Corynebacterium diphtheriae histidine kinase ChrS (DIP2326) SWALL:Q9RPF0 (EMBL:AF161327) (417 aa) fasta scores: E(): 8.2e-25, 31.17% id in 401 aa NP_940573.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate NP_940574.1 Similar to Streptomyces coelicolor hypothetical 8.0 kDa protein SCH69.22c SWALL:Q9XA12 (EMBL:AL079308) (69 aa) fasta scores: E(): 1.3e-05, 40% id in 50 aa NP_940575.1 Similar to Clostridium acetobutylicum sortase CAC0204 TR:AAK78186 (EMBL:AE007533) (194 aa) fasta scores: E(): 2.6e-06, 30.872% id in 149 aa, and weakly similar to Actinomyces naeslundii fimbria-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 0.25, 32.941% id in 85 aa, and to Streptococcus pneumoniae TIGR4 sortase, SP0466 TR:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 5.3, 25.000% id in 144 aa NP_940576.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_940577.1 Similar to many eg. Streptomyces coelicolor transcriptional regulator SCD6.32c SWALL:Q9KZX2 (EMBL:AL353815) (200 aa) fasta scores: E(): 8.4e-15, 36.72% id in 177 aa NP_940578.1 Similar to Mycobacterium tuberculosis hypothetical 10.3 kDa protein Rv1861 or MTCY359.12c SWALL:P95154 (EMBL:Z83859) (101 aa) fasta scores: E(): 1.6e-10, 47.72% id in 88 aa, and to Escherichia coli transglycosylase associated protein YmgE or Tag or B1195 SWALL:TAG1_ECOLI (SWALL:P76011) (84 aa) fasta scores: E(): 2.5e-05, 38.82% id in 85 aa NP_940579.1 Similar to many including predicted universal stress proteins eg. Mycobacterium tuberculosis hypothetical 30.9 kDa protein Rv2005c or MT2061 or MTCY39.12 SWALL:YK05_MYCTU (SWALL:Q10851) (295 aa) fasta scores: E(): 1.7e-32, 40.87% id in 296 aa, and to Mycobacterium tuberculosis CDC1551 universal stress protein family MT2698 SWALL:AAK47014 (EMBL:AE007102) (297 aa) fasta scores: E(): 1.7e-30, 36.73% id in 294 aa NP_940580.1 Similar to hypothetical proteins and proposed ribosomal pseudouridine synthases eg. Mycobacterium tuberculosis hypothetical 33.3 kDa protein Rv3300c or MT3399 or MTCI418A.02c SWALL:O07166 (EMBL:Z96070) (305 aa) fasta scores: E(): 6.3e-23, 45.74% id in 247 aa, and to Streptomyces coelicolor ribosomal pseudouridine synthase SCI41.08 SWALL:Q9RJ76 (EMBL:AL132648) (324 aa) fasta scores: E(): 1.9e-22, 40.69% id in 317 aa NP_940581.1 No significant database matches. Lies downstream of a ABC transporter ATP-binding subunit NP_940582.1 Similar to many eg. Bacillus halodurans ABC transporter BH3493 SWALL:Q9K777 (EMBL:AP001519) (283 aa) fasta scores: E(): 3.8e-18, 33.97% id in 209 aa, and to Bacillus subtilis hypothetical ABC transporter ATP-binding protein YhcG SWALL:YHCG_BACSU (SWALL:P54591) (232 aa) fasta scores: E(): 4.1e-12, 31.01% id in 216 aa NP_940583.1 Similar to many eg. Bacillus halodurans transcriptional regulator BH3492 SWALL:Q9K778 (EMBL:AP001519) (129 aa) fasta scores: E(): 6.6e-15, 43.36% id in 113 aa NP_940584.1 Similar to Streptomyces coelicolor hypothetical 44.0 kDa protein SC4G6.31c SWALL:Q9S2S7 (EMBL:AL096884) (403 aa) fasta scores: E(): 4.6e-09, 25.49% id in 459 aa NP_940585.1 Similar to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SWALL:35KD_MYCTU (SWALL:P31511) (270 aa) fasta scores: E(): 8.4e-29, 45.52% id in 257 aa NP_940586.1 Similar to Streptomyces coelicolor thioredoxin TrxA2 SWALL:Q9RD25 (EMBL:AL133422) (134 aa) fasta scores: E(): 1.7e-23, 52.89% id in 121 aa, and to Escherichia coli thioredoxin 2 TrxC or B2582 or Z3867 or ECS3448 SWALL:THI2_ECOLI (SWALL:P33636) (139 aa) fasta scores: E(): 5.9e-11, 38% id in 100 aa NP_940587.1 Similar to Streptomyces coelicolor metal associated protein SCG20A.25 SWALL:Q9K3L5 (EMBL:AL360055) (77 aa) fasta scores: E(): 1.3e-05, 45.9% id in 61 aa, and to Helicobacter felis cop associated protein CopP SWALL:COPP_HELFE (SWALL:O32620) (66 aa) fasta scores: E(): 0.0074, 36.92% id in 65 aa NP_940588.1 Similar to Streptomyces coelicolor probable cation-transporting P-type ATPase SCC57A.02 SWALL:Q9RDJ4 (EMBL:AL136519) (760 aa) fasta scores: E(): 7e-146, 60.21% id in 744 aa, and to Rhizobium meliloti copper-transporting ATPase ActP SWALL:ATCU_RHIME (SWALL:Q9X5X3) (827 aa) fasta scores: E(): 1.3e-84, 42.12% id in 762 aa NP_940589.1 Similar to Deinococcus radiodurans sugar transporter, DRA0271 SWALL:Q9RYN9 (EMBL:AE001863) (454 aa) fasta scores: E(): 9.2e-54, 41.12% id in 445 aa, and to Pseudomonas putida 4-hydroxybenzoate transporter PcaK SWALL:PCAK_PSEPU (SWALL:Q51955) (448 aa) fasta scores: E(): 1.8e-25, 30.4% id in 398 aa NP_940590.1 unwinds double stranded DNA NP_940591.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_940592.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_940593.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_940595.1 Similar to Streptomyces coelicolor transmembrane protein SCH24.24 SWALL:Q9X8T8 (EMBL:AL049826) (502 aa) fasta scores: E(): 7.8e-37, 36.2% id in 453 aa NP_940596.1 Similar to Mycobacterium smegmatis penicillin-binding protein 1 PonA SWALL:Q9F9V7 (EMBL:AF165523) (715 aa) fasta scores: E(): 4.1e-105, 51.23% id in 689 aa, and to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 1.4e-32, 29.44% id in 720 aa NP_940597.1 Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv0049 or MT0055 or MTCY21D4.12 SWALL:Y049_MYCTU (SWALL:P71706) (137 aa) fasta scores: E(): 1e-15, 47.52% id in 101 aa NP_940598.1 Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, MarR family MT0048 SWALL:AAK44270 (EMBL:AE006918) (208 aa) fasta scores: E(): 1.9e-07, 34.72% id in 144 aa, and to Streptomyces coelicolor MarR-family transcriptional regulator SC6D11.20 SWALL:Q9L135 (EMBL:AL158061) (155 aa) fasta scores: E(): 4.7e-05, 33.05% id in 121 aa NP_940599.1 Similar to Mycobacterium tuberculosis hypothetical 31.9 kDa protein Rv2319c or MT2382 or MTCY3G12.15 SWALL:YN19_MYCTU (SWALL:P71893) (292 aa) fasta scores: E(): 4.3e-21, 28% id in 300 aa NP_940600.1 Similar to Bacillus subtilis hypothetical oxidoreductase YoxD SWALL:YOXD_BACSU (SWALL:P14802) (238 aa) fasta scores: E(): 2.2e-09, 28.57% id in 231 aa, and to Rhizobium sp short-chain type dehydrogenase/reductase SWALL:Y4EK_RHISN (SWALL:P55434) (248 aa) fasta scores: E(): 2.3e-09, 30% id in 210 aa NP_940602.1 Regions similar to Pyrococcus abyssi hypothetical 32.8 kDa protein PAB0790 SWALL:Q9UZG6 (EMBL:AJ248286) (287 aa) fasta scores: E(): 1.4e-09, 27.45% id in 306 aa, and to Thiobacillus ferrooxidans ATP-dependent DNA helicase RecG SWALL:RECG_THIFE (SWALL:O50224) (652 aa) fasta scores: E(): 1.9e-07, 30.04% id in 223 aa NP_940603.1 Similar to Staphylococcus aureus (strain N315) conserved hypothetical protein SA2481 or SAV2689 SWALL:Q99QV2 (EMBL:AP003138) (318 aa) fasta scores: E(): 3.6e-25, 34.68% id in 297 aa NP_940604.1 Similar to Streptomyces coelicolor integral membrane protein SC4A9.02c SWALL:Q9L1W0 (EMBL:AL138668) (231 aa) fasta scores: E(): 8.7e-31, 41.5% id in 200 aa NP_940605.1 Similar to Haemophilus ducreyi fine tangled pili major subunit FtpA SWALL:FTPA_HAEDU (SWALL:Q47953) (189 aa) fasta scores: E(): 3.5e-23, 46.83% id in 158 aa, and to Escherichia coli DNA protection during starvation protein Dps or Pexb or Vtm or B0812 or Z1034 or ECS0890 SWALL:DPS_ECOLI (SWALL:P27430) (166 aa) fasta scores: E(): 1.6e-14, 38.31% id in 154 aa NP_940606.1 Similar to Streptomyces coelicolor DNA repair hydrolase SCC80.11c SWALL:Q9F308 (EMBL:AL442143) (306 aa) fasta scores: E(): 1.1e-52, 53.22% id in 295 aa, and to Escherichia coli formamidopyrimidine-DNA glycosylase MutM or Fpg or B3635 SWALL:FPG_ECOLI (SWALL:P05523) (269 aa) fasta scores: E(): 1.2e-12, 29.21% id in 243 aa NP_940607.1 Similar to Mycobacterium tuberculosis hypothetical 46.9 kDa protein Rv3433c or MT3539 or MTCY77.05c SWALL:YY33_MYCTU (SWALL:O06250) (473 aa) fasta scores: E(): 1.8e-30, 41.96% id in 510 aa NP_940608.1 Similar to Saccharopolyspora erythraea lysozyme SWALL:O33985 (EMBL:U82823) (241 aa) fasta scores: E(): 1.3e-23, 36.9% id in 233 aa, and to Clostridium acetobutylicum autolytic lysozyme Lyc or CAC0554 SWALL:LYC_CLOAB (SWALL:P34020) (324 aa) fasta scores: E(): 4.7e-10, 28.27% id in 191 aa NP_940610.1 Similar to proteins associated with plasmid replication-partitioning eg. Plesiomonas shigelloides hypothetical SoJ-like protein Soj SWALL:Q9RLE7 (EMBL:AJ249644) (182 aa) fasta scores: E(): 1.8e-05, 29.31% id in 191 aa, and to Pseudomonas fluorescens ParA protein SWALL:Q9RLI2 (EMBL:AJ250853) (394 aa) fasta scores: E(): 3.4e-05, 28.77% id in 212 aa, and to Thermus thermophilus partitioning protein ParA/Soj SWALL:Q9LCY1 (EMBL:AJ277593) (248 aa) fasta scores: E(): 0.00017, 31.63% id in 196 aa, and to Lactobacillus reuteri replication-associated protein A RepA SWALL:O52364 (EMBL:AF036766) (295 aa) fasta scores: E(): 0.00042, 28.91% id in 211 aa NP_940612.1 Similar to N-terminal half of Pyrococcus abyssi hypothetical 48.8 kDa protein Pab1002 SWALL:Q9UYK0 (EMBL:AJ248287) (428 aa) fasta scores: E(): 0.081, 30.05% id in 193 aa NP_940613.1 Similar to Deinococcus radiodurans ATP-dependent DNA helicase RecG-related protein DR2199 SWALL:Q9RSC6 (EMBL:AE002053) (596 aa) fasta scores: E(): 1.1e-09, 27.17% id in 574 aa, and to Thiobacillus ferrooxidans ATP-dependent DNA helicase RecG SWALL:RECG_THIFE (SWALL:O50224) (652 aa) fasta scores: E(): 7.7e-05, 33.08% id in 133 aa NP_940614.1 Similar to Pasteurella haemolytica HsdR SWALL:P95512 (EMBL:U46781) (1055 aa) fasta scores: E(): 1.4e-61, 34.88% id in 1055 aa NP_940615.1 Similar to Lactococcus lactis HsdS subunit SWALL:O68173 (EMBL:AF013596) (395 aa) fasta scores: E(): 2.7e-13, 33.72% id in 172 aa, and to Streptococcus thermophilus type I S-subunit protein HsdS SWALL:O52188 (EMBL:AF027167) (412 aa) fasta scores: E(): 1.6e-12, 27.84% id in 334 aa NP_940616.1 Similar to Klebsiella pneumoniae HsdM SWALL:O34139 (EMBL:U93843) (539 aa) fasta scores: E(): 6.2e-66, 45.37% id in 551 aa, and to Pasteurella multocida HsdM or PM1537 SWALL:Q9CKR9 (EMBL:AE006190) (568 aa) fasta scores: E(): 2e-51, 44.38% id in 561 aa NP_940618.1 Similar to Arthrobacter keyseri hypothetical 45.9 kDa protein TnpX SWALL:Q9AGM1 (EMBL:AF331043) (421 aa) fasta scores: E(): 9.4e-26, 33.86% id in 378 aa, and to Agrobacterium tumefaciens STRC58 AGR_PAT_51p SWALL:AAK90413 (EMBL:AE007876) (393 aa) fasta scores: E(): 1.9e-19, 29.67% id in 374 aa NP_940619.1 Similar to Vibrio cholerae hypothetical protein VCA0786 SWALL:Q9KLF8 (EMBL:AE004407) (549 aa) fasta scores: E(): 1.3e-63, 42.28% id in 570 aa, and to Aeropyrum pernix hypothetical 61.1 kDa protein APE1810 ape1810 SWALL:Q9YAY5 (EMBL:AP000062) (558 aa) fasta scores: E(): 1.5e-39, 33.5% id in 570 aa NP_940620.1 Similar to Mycobacterium paratuberculosis copper zinc superoxide dismutase SodC SWALL:Q9AGW2 (EMBL:AF326234) (226 aa) fasta scores: E(): 1.4e-18, 41.36% id in 220 aa, and to Caulobacter crescentus superoxide dismutase [Cu-Zn] precursor SodC or CC1579 SWALL:SODC_CAUCR (SWALL:P20379) (174 aa) fasta scores: E(): 2e-12, 35.13% id in 185 aa NP_940621.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_940622.1 Doubtful CDS. No significant database matches NP_940624.1 Similar to Streptomyces coelicolor ABC transport system ATP-binding protein SC10A9.09c SWALL:Q9AK95 (EMBL:AL583943) (251 aa) fasta scores: E(): 4.7e-31, 51.35% id in 222 aa NP_940625.1 Similar to Streptomyces coelicolor ABC transport system transmembrane protein SC10A9.10c SWALL:Q9AK94 (EMBL:AL583943) (379 aa) fasta scores: E(): 4.3e-17, 38.94% id in 380 aa. Lies alongside a ABC transporter ATP-binding subunit NP_940626.1 No significant database matches. Note: Contains a potential sortase anchor site (LAETG) upstream of the C-terminal region transmembrane domain. Also similar to DIP0439, DIP1724, DIP0442 and DIP0443 NP_940627.1 Previously sequenced and described as Corynebacterium diphtheriae histidine kinase ChrS SWALL:Q9RPF0 (EMBL:AF161327) (417 aa) fasta scores: E(): 4e-136, 88.72% id in 417 aa. Similar to many eg. Streptomyces reticuli histidine autokinase SenS SWALL:Q9RIM1 (EMBL:Y14336) (398 aa) fasta scores: E(): 1.6e-21, 35.28% id in 411 aa NP_940628.1 Previously sequenced and described as Corynebacterium diphtheriae response regulator ChrA SWALL:Q9RPE9 (EMBL:AF161327) (199 aa) fasta scores: E(): 2.7e-67, 98.49% id in 199 aa. Similar to many eg. Streptomyces reticuli response regulatory protein SenR SWALL:Q9RIM0 (EMBL:Y14336) (217 aa) fasta scores: E(): 1.5e-28, 49.51% id in 204 aa NP_940629.1 Similar to Clostridium acetobutylicum uncharacterized conserved membrane protein, similar to Mdr CAC0829 SWALL:AAK78805 (EMBL:AE007599) (308 aa) fasta scores: E(): 0.0003, 25.88% id in 170 aa, and has region in common with Enterococcus faecium protein VanZ SWALL:VANZ_ENTFC (SWALL:Q06242) (161 aa) fasta scores: E(): 0.19, 29.16% id in 96 aa NP_940630.1 Weak but full length similarity to many eg. Clostridium acetobutylicum uncharacterized conserved membrane protein, YhgE B.subtilis ortholog CAC3589 SWALL:AAK81512 (EMBL:AE007855) (783 aa) fasta scores: E(): 1.6e-16, 23.62% id in 766 aa NP_940631.1 No significant database matches. Lies in DNA region of low GC content. NP_940632.1 Similar to Deinococcus radiodurans succinate-semialdehyde dehydrogenase [NADP+] SsdA or DRA0343 SWALL:GABD_DEIRA (SWALL:O32507) (477 aa) fasta scores: E(): 1.2e-81, 49.44% id in 453 aa, and to Streptomyces coelicolor aldehyde dehydrogenase 2SCG58.04 SWALL:Q9FCA9 (EMBL:AL391017) (461 aa) fasta scores: E(): 4.1e-65, 42.57% id in 458 aa, and to Ustilago maydis indole-3-acetaldehyde dehydrogenase Iad1 SWALL:Q92460 (EMBL:U74468) (497 aa) fasta scores: E(): 1.6e-48, 37.04% id in 467 aa NP_940633.1 Similar to Streptomyces coelicolor hypothetical 17.6 kDa protein SCJ21.18C SWALL:Q9S1Y9 (EMBL:AL109747) (170 aa) fasta scores: E(): 3e-29, 56.97% id in 172 aa, and to Escherichia coli unknown pentitol II, A component SgaA or B4195 or Z5804 or ECS5171 SWALL:PTXA_ECOLI (SWALL:P39303) (154 aa) fasta scores: E(): 1.3e-12, 39.82% id in 113 aa NP_940634.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr NP_940635.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase NP_940636.1 Similar to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak2 SWALL:AAG14892 (EMBL:AF297121) (207 aa) fasta scores: E(): 6.6e-25, 48.51% id in 202 aa, and to Escherichia coli protein YcgS or B1199 SWALL:YCGS_ECOLI (SWALL:P76014) (210 aa) fasta scores: E(): 2e-22, 43.12% id in 211 aa. Lies downstream of a Dhak1 homologue NP_940637.1 Similar to but longer than a family of hypothetical proteins eg. Deinococcus radiodurans conserved hypothetical protein DRB0052 SWALL:Q9RZR3 (EMBL:AE001826) (133 aa) fasta scores: E(): 8.8e-10, 43.75% id in 128 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0607 or SAV0652 SWALL:Q99VW9 (EMBL:AP003131) (120 aa) fasta scores: E(): 1.3e-09, 42.73% id in 117 aa NP_940638.1 Similar to Lactococcus lactis abortive phage resistance protein AbilI SWALL:O06042 (EMBL:U94520) (458 aa) fasta scores: E(): 7.4e-08, 26.39% id in 466 aa. Lies in DNA region of low GC content. NP_940640.1 Similar to a family of proteins members of which are part of the antigen 85 complex responsible for the high affinity of mycobacteria for fibronectin. Similar to Corynebacterium ammoniagenes surface layer protein A SlpA SWALL:BAB62413 (EMBL:AB055224) (358 aa) fasta scores: E(): 2.6e-18, 31.23% id in 317 aa, and to Mycobacterium tuberculosis antigen 85-A precursor FbpA or Mpt44 or Rv3804c or MT3911 or MTV026.09c SWALL:A85A_MYCTU (SWALL:P17944) (338 aa) fasta scores: E(): 4.4e-18, 32.14% id in 280 aa, and to Corynebacterium glutamicum PS1 protein precursor Csp1 SWALL:CSP1_CORGL (SWALL:Q01377) (657 aa) fasta scores: E(): 5.2e-16, 30.02% id in 403 aa NP_940641.1 Similar to members of a family of nucleoside hydrolases eg. Mycobacterium tuberculosis nucleoside hydrolase IunH or Rv3393 or MTV004.51 SWALL:O50418 (EMBL:AL009198) (308 aa) fasta scores: E(): 7.6e-27, 36.07% id in 316 aa, and to Crithidia fasciculata inosine-uridine preferring nucleoside hydrolase IunH SWALL:IUNH_CRIFA (SWALL:Q27546) (314 aa) fasta scores: E(): 2.7e-14, 28.07% id in 317 aa NP_940642.1 Similar to Escherichia coli O157:H7 transporter ECS3800 SWALL:BAB37223 (EMBL:AP002563) (192 aa) fasta scores: E(): 6e-15, 30.16% id in 179 aa. Lies alongside a ABC transporter ATP-binding subunit NP_940643.1 Similar to Streptomyces coelicolor integral membrane transport protein SCE87.11 SWALL:Q9RKC7 (EMBL:AL132674) (253 aa) fasta scores: E(): 0.082, 26.54% id in 226 aa NP_940644.1 Similar to Streptomyces coelicolor ABC transporter ATP-binding subunit SCC53.15 SWALL:Q9KXJ6 (EMBL:AL357591) (563 aa) fasta scores: E(): 1.9e-05, 26.87% id in 439 aa, and to Methanobacterium thermoautotrophicum cobalt transport ATP-binding protein CbiO SWALL:Q50801 (EMBL:X94292) (277 aa) fasta scores: E(): 0.00012, 30.4% id in 171 aa NP_940645.1 Weakly similar to many eg. Escherichia coli unknown protein from 2d-page YeaD or B1780 SWALL:UP08_ECOLI (SWALL:P39173) (294 aa) fasta scores: E(): 0.00013, 28.74% id in 247 aa NP_940647.1 Similar to proteins from streptococci eg. Streptococcus pneumoniae hypothetical protein Sp0341 SWALL:AAK74515 (EMBL:AE007346) (494 aa) fasta scores: E(): 3.6e-101, 51.82% id in 492 aa, and to Streptococcus pyogenes hypothetical protein Spy1343 SWALL:Q99Z89 (EMBL:AE006572) (518 aa) fasta scores: E(): 8.2e-100, 50.9% id in 495 aa NP_940648.1 Weakly similar to Rhizobium meliloti hypothetical protein Smc02732 r02394 or smc02732 TR:CAC46973 (EMBL:AL591790) (134 aa) fasta scores: E(): 1.4, 32.92% id in 82 aa NP_940649.1 Weakly similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv2011c precursor or MT2066 or MTCY39.06 SW:YK11_MYCTU (Q10846) (143 aa) fasta scores: E(): 5.2, 26.66% id in 135 aa NP_940650.1 Similar to Treponema pallidum glutamate/aspartate transporter, tp0555 TR:O83566 (EMBL:AE001231) (396 aa) fasta scores: E(): 2.9e-33, 33.86% id in 375 aa NP_940652.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_940653.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine NP_940654.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity NP_940655.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_940656.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate NP_940657.1 Similar to Neisseria meningitidis membrane protein NMA0754 TR:Q9JVP6 (EMBL:AL162754) (119 aa) fasta scores: E(): 3.9e-14, 47.67% id in 86 aa, and to Escherichia coli, and hypothetical protein YanB or B0468 or Z0585 or ECS0521 SW:YBAN_ECOLI (P45808) (125 aa) fasta scores: E(): 1.2e-10, 37.83% id in 111 aa NP_940658.1 Similar to Mycobacterium tuberculosis pantoate--beta-alanine ligase PanC or Rv3602c or MT3707 or MTCY07H7B.20 SW:PANC_MYCTU (O06280) (309 aa) fasta scores: E(): 1e-42, 47.65% id in 277 aa, and to Corynebacterium glutamicum pantoate--beta-alanine ligase PanC SW:PANC_CORGL (Q9X713) (279 aa) fasta scores: E(): 1.8e-32, 42.65% id in 279 aa NP_940659.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_940660.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_940661.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_940662.1 Similar to Mycobacterium smegmatis Rieske iron-sulfur protein QcrA TR:Q9XBV4 (EMBL:AF155062) (138 aa) fasta scores: E(): 1.7e-11, 40.9% id in 132 aa, and to Streptomyces coelicolor iron-sulphur protein SCI51.03 TR:Q9S237 (EMBL:AL109848) (131 aa) fasta scores: E(): 3.8e-10, 35.15% id in 128 aa NP_940663.1 Similar to Streptomyces coelicolor transmembrane protein SC4B5.06 TR:Q9ZBW2 (EMBL:AL034443) (345 aa) fasta scores: E(): 1.3e-52, 52.73% id in 311 aa NP_940665.1 Similar to Bacillus subtilis branched-chain amino acid transport protein AzlD SW:AZLD_BACSU (O07923) (110 aa) fasta scores: E(): 8.2e-05, 36.27% id in 102 aa NP_940666.1 Similar to Bacillus subtilis branched-chain amino acid transport protein AzlC SW:AZLC_BACSU (O07942) (254 aa) fasta scores: E(): 4.2e-14, 29.38% id in 211 aa NP_940667.1 Similar to Mycobacterium tuberculosis hypothetical 21.8 kDa protein Rv0038 or MT0043 or MTCY10h4.38 SW:Y038_MYCTU (P71608) (202 aa) fasta scores: E(): 4.4e-28, 43.64% id in 181 aa NP_940668.1 Similar to a family of proteins from both prokaryotes and eukaryotes and including poly A polymerases and tRNA nucleotidyl transferases. Since prokaryotes don't generally have poly A tailed mRNAs the prokaryotic proteins are likely to be RNA nucleotidyl transferases. Similar to Mycobacterium tuberculosis PcnA or Rv3907c or MTCY15F10.04 TR:O05438 (EMBL:Z94121) (480 aa) fasta scores: E(): 3.5e-119, 64.61% id in 472 aa, and to Streptomyces coelicolor RNA nucleotidyltransferase SCH24.18 TR:Q9X8T2 (EMBL:AL049826) (483 aa) fasta scores: E(): 1.3e-103, 58.06% id in 465 aa. Similar to Escherichia coli tRNA nucleotidyltransferase Cca or B3056 SW:CCA_ECOLI (P06961) blast scores: E(): 2e-20, score: 250 30% id NP_940669.1 Extensive (but not full length) similarity to Mycobacterium tuberculosis hypothetical 27.1 kDa protein Rv3908 or MTCY15f10.03C TR:O05437 (EMBL:Z94121) (248 aa) fasta scores: E(): 2.3e-25, 47.39% id in 211 aa. Has a hydrophilic N-terminal region. NP_940670.1 Weak but full length similarity to Mycobacterium tuberculosis hypothetical 83.9 kDa protein Rv3909 or MTCY15F10.02c TR:O05436 (EMBL:Z94121) (802 aa) fasta scores: E(): 8.4e-10, 25.54% id in 916 aa NP_940671.1 Similar to Mycobacterium tuberculosis hypothetical 123.6 kDa protein Rv3910 or MTCY15F10.01c or MTV028.01 TR:O05435 (EMBL:Z94121) (1184 aa) fasta scores: E(): 1.1e-83, 35.58% id in 1200 aa, and to Rhizobium tropici virulence factor MviN homolog SW:MVIN_RHITR (O05467) (533 aa) fasta scores: E(): 5.7e-15, 23.87% id in 553 aa NP_940672.1 Similar to Pseudomonas fluorescens alternative sigma factor AlgU TR:AAK94006 (EMBL:AF399758) (193 aa) fasta scores: E(): 8.1e-12, 30.1% id in 186 aa, and to Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU or AlgT or PA0762 SW:RPSH_PSEAE (Q06198) (193 aa) fasta scores: E(): 1.8e-11, 29.03% id in 186 aa NP_940673.1 Similar to Mycobacterium smegmatis thioredoxin reductase TrxB SW:TRXB_MYCSM (O30973) (311 aa) fasta scores: E(): 3.1e-72, 64.82% id in 307 aa NP_940674.1 Similar to Mycobacterium smegmatis thioredoxin TrxA SW:THIO_MYCSM (O30974) (112 aa) fasta scores: E(): 5.8e-18, 48.14% id in 108 aa NP_940675.1 Similar to Mycobacterium tuberculosis hydrolase CwlM or Rv3915 or MTV028.06 TR:O53593 (EMBL:AL021426) (406 aa) fasta scores: E(): 5.4e-78, 52.38% id in 399 aa, and to Bacillus subtilis N-acetylmuramoyl-L-alanine amidase CwlB precursor or LytC SW:CWLB_BACSU (Q02114) (496 aa) fasta scores: E(): 2.8e-07, 25.62% id in 199 aa NP_940676.1 Similar to Mycobacterium tuberculosis probable chromosome partitioning protein ParB or Rv3917c or MT4036 or MTV028.08c SW:PARB_MYCTU (O53595) (344 aa) fasta scores: E(): 7.4e-47, 54.93% id in 375 aa, and to Streptomyces coelicolor chromosome partitioning protein ParB TR:Q9RFM2 (EMBL:AF187159) (368 aa) fasta scores: E(): 3.2e-43, 47.69% id in 369 aa NP_940677.1 Similar to Streptomyces coelicolor chromosome partitioning protein ParA TR:Q9RFM1 (EMBL:AF187159) (357 aa) fasta scores: E(): 2.5e-64, 63.6% id in 294 aa, and to Bacillus subtilis sporulation initiation inhibitor protein Soj SW:SOJ_BACSU (P37522) (253 aa) fasta scores: E(): 2.8e-45, 54.15% id in 253 aa NP_940678.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_940679.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_940680.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_940681.1 in Escherichia coli transcription of this gene is enhanced by polyamines