-- dump date   	20140619_051151
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
257309000001	chromosomal replication initiation protein; Provisional; Region: dnaA; PRK14086
257309000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309000003	Walker A motif; other site
257309000004	ATP binding site [chemical binding]; other site
257309000005	Walker B motif; other site
257309000006	arginine finger; other site
257309000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
257309000008	DnaA box-binding interface [nucleotide binding]; other site
257309000009	HMMPfam hit to PF00308, Bacterial dnaA protein
257309000010	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000011	FPrintScan hit to PR00051, Bacterial chromosomal replication initiator (DNAA) signature
257309000012	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000013	FPrintScan hit to PR00051, Bacterial chromosomal replication initiator (DNAA) signature
257309000014	FPrintScan hit to PR00051, Bacterial chromosomal replication initiator (DNAA) signature
257309000015	FPrintScan hit to PR00051, Bacterial chromosomal replication initiator (DNAA) signature
257309000016	FPrintScan hit to PR00051, Bacterial chromosomal replication initiator (DNAA) signature; ScanRegExp hit to PS01008, DnaA protein signature.
257309000017	DNA polymerase III subunit beta; Validated; Region: PRK07761
257309000018	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
257309000019	putative DNA binding surface [nucleotide binding]; other site
257309000020	dimer interface [polypeptide binding]; other site
257309000021	beta-clamp/clamp loader binding surface; other site
257309000022	beta-clamp/translesion DNA polymerase binding surface; other site
257309000023	HMMPfam hit to PF00712, DNA polymerase III beta subunit, N-terminal domain
257309000024	HMMSmart hit to SM00480, DNA polymerase III beta catalytic subunit
257309000025	HMMPfam hit to PF02767, DNA polymerase III beta subunit, central domain
257309000026	HMMPfam hit to PF02768, DNA polymerase III beta subunit, C-terminal domain
257309000027	recombination protein F; Reviewed; Region: recF; PRK00064
257309000028	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
257309000029	Walker A/P-loop; other site
257309000030	ATP binding site [chemical binding]; other site
257309000031	Q-loop/lid; other site
257309000032	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309000033	ABC transporter signature motif; other site
257309000034	Walker B; other site
257309000035	D-loop; other site
257309000036	H-loop/switch region; other site
257309000037	HMMPfam hit to PF00470, RecF protein
257309000038	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000039	ScanRegExp hit to PS00617, RecF protein signature 1.
257309000040	ScanRegExp hit to PS00618, RecF protein signature 2.
257309000041	hypothetical protein; Provisional; Region: PRK00111
257309000042	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
257309000043	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309000044	ATP binding site [chemical binding]; other site
257309000045	Mg2+ binding site [ion binding]; other site
257309000046	G-X-G motif; other site
257309000047	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
257309000048	anchoring element; other site
257309000049	dimer interface [polypeptide binding]; other site
257309000050	ATP binding site [chemical binding]; other site
257309000051	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
257309000052	active site
257309000053	putative metal-binding site [ion binding]; other site
257309000054	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
257309000055	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000056	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309000057	HMMSmart hit to SM00433, TopoisomeraseII
257309000058	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000059	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000060	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000061	HMMPfam hit to PF00204, DNA topoisomerase II (N-terminal region)
257309000062	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000063	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000064	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000065	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000066	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000067	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000068	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000069	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000070	ScanRegExp hit to PS00177, DNA topoisomerase II signature.
257309000071	HMMPfam hit to PF01751, Toprim domain
257309000072	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000073	BlastProDom hit to PD000616, PD000616
257309000074	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000075	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000076	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000077	HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus
257309000078	BlastProDom hit to PD149633, PD149633
257309000079	FPrintScan hit to PR00418, DNA topoisomerase II family signature
257309000080	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000081	FPrintScan hit to PR01159, DNA gyrase subunit B signature
257309000082	DNA gyrase subunit A; Validated; Region: PRK05560
257309000083	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
257309000084	CAP-like domain; other site
257309000085	active site
257309000086	primary dimer interface [polypeptide binding]; other site
257309000087	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
257309000088	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
257309000089	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
257309000090	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
257309000091	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
257309000092	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
257309000093	HMMSmart hit to SM00434, DNA Topoisomerase IV
257309000094	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A
257309000095	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309000096	Transmembrane domain of unknown function (DUF3566); Region: DUF3566; pfam12089
257309000097	2 probable transmembrane helices predicted for DIP0010 by TMHMM2.0
257309000098	Transcriptional regulators [Transcription]; Region: FadR; COG2186
257309000099	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309000100	DNA-binding site [nucleotide binding]; DNA binding site
257309000101	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
257309000102	HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309000103	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family
257309000104	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309000105	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309000106	Predicted helix-turn-helix motif with score 1020 (+2.66 SD) at aa 34-55, sequence PGERALAEQFELSRASVREAIR
257309000107	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309000108	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
257309000109	L-lactate permease; Region: Lactate_perm; cl00701
257309000110	13 probable transmembrane helices predicted for DIP0012 by TMHMM2.0
257309000111	HMMPfam hit to PF02652, L-lactate permease
257309000112	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309000113	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309000114	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309000115	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309000116	Cadherin repeat-like domain; Region: CA_like; cl15786
257309000117	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309000118	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309000119	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
257309000120	Walker A/P-loop; other site
257309000121	ATP binding site [chemical binding]; other site
257309000122	Q-loop/lid; other site
257309000123	ABC transporter signature motif; other site
257309000124	Walker B; other site
257309000125	D-loop; other site
257309000126	H-loop/switch region; other site
257309000127	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309000128	6 probable transmembrane helices predicted for DIP0014 by TMHMM2.0
257309000129	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000130	HMMPfam hit to PF00005, ABC transporter
257309000131	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000132	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000133	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000134	ScanRegExp hit to PS00211, ABC transporters family signature.
257309000135	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309000136	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
257309000137	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309000138	Walker A/P-loop; other site
257309000139	ATP binding site [chemical binding]; other site
257309000140	Q-loop/lid; other site
257309000141	ABC transporter signature motif; other site
257309000142	Walker B; other site
257309000143	D-loop; other site
257309000144	H-loop/switch region; other site
257309000145	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309000146	5 probable transmembrane helices predicted for DIP0015 by TMHMM2.0
257309000147	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000148	HMMPfam hit to PF00005, ABC transporter
257309000149	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000150	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000151	ScanRegExp hit to PS00211, ABC transporters family signature.
257309000152	2 probable transmembrane helices predicted for DIP0016 by TMHMM2.0
257309000153	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
257309000154	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
257309000155	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312
257309000156	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
257309000157	putative ligand binding site [chemical binding]; other site
257309000158	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar binding domain of the LacI family.
257309000159	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
257309000160	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
257309000161	TM-ABC transporter signature motif; other site
257309000162	9 probable transmembrane helices predicted for DIP0022 by TMHMM2.0
257309000163	ProfileScan hit to PS50281, Binding-system dependent bacterial transporters (araH, livH/limM families)
257309000164	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309000165	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
257309000166	Walker A/P-loop; other site
257309000167	ATP binding site [chemical binding]; other site
257309000168	Q-loop/lid; other site
257309000169	ABC transporter signature motif; other site
257309000170	Walker B; other site
257309000171	D-loop; other site
257309000172	H-loop/switch region; other site
257309000173	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000174	HMMPfam hit to PF00005, ABC transporter
257309000175	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000176	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000177	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000178	ScanRegExp hit to PS00211, ABC transporters family signature.
257309000179	1 probable transmembrane helix predicted for DIP0024 by TMHMM2.0
257309000180	ProfileScan hit to PS50318, Lysine-rich region.
257309000181	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
257309000182	active site
257309000183	ProfileScan hit to PS50072, Cyclophilin-type peptidyl-prolyl cis-trans isomerase profile.
257309000184	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-trans isomerase
257309000185	FPrintScan hit to PR00153, Cyclophilin peptidyl-prolyl cis-trans isomerase signature
257309000186	FPrintScan hit to PR00153, Cyclophilin peptidyl-prolyl cis-trans isomerase signature
257309000187	ScanRegExp hit to PS00284, Serpins signature.
257309000188	FPrintScan hit to PR00153, Cyclophilin peptidyl-prolyl cis-trans isomerase signature
257309000189	FPrintScan hit to PR00153, Cyclophilin peptidyl-prolyl cis-trans isomerase signature
257309000190	FPrintScan hit to PR00153, Cyclophilin peptidyl-prolyl cis-trans isomerase signature
257309000191	Integrase core domain; Region: rve_2; pfam13333
257309000192	HMMPfam hit to PF00665, Integrase core domain
257309000193	Rhomboid family; Region: Rhomboid; pfam01694
257309000194	6 probable transmembrane helices predicted for DIP0027 by TMHMM2.0
257309000195	HMMPfam hit to PF01694, Rhomboid family
257309000196	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
257309000197	ThiC-associated domain; Region: ThiC-associated; pfam13667
257309000198	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
257309000199	BlastProDom hit to PD007048, PD007048
257309000200	HMMPfam hit to PF01964, ThiC family
257309000201	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
257309000202	thiamine phosphate binding site [chemical binding]; other site
257309000203	active site
257309000204	pyrophosphate binding site [ion binding]; other site
257309000205	HMMPfam hit to PF02581, Thiamine monophosphate synthase/TENI
257309000206	hydroxyglutarate oxidase; Provisional; Region: PRK11728
257309000207	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
257309000208	HMMPfam hit to PF01266, FAD dependent oxidoreductase
257309000209	ProfileScan hit to PS50205, NAD binding site.
257309000210	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
257309000211	thiS-thiF/thiG interaction site; other site
257309000212	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
257309000213	ThiS interaction site; other site
257309000214	putative active site [active]
257309000215	tetramer interface [polypeptide binding]; other site
257309000216	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309000217	thiamine biosynthesis protein ThiF; Validated; Region: PRK05600
257309000218	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
257309000219	ATP binding site [chemical binding]; other site
257309000220	substrate interface [chemical binding]; other site
257309000221	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
257309000222	active site residue [active]
257309000223	ProfileScan hit to PS50204, UBA/THIF-type NAD binding fold.
257309000224	HMMPfam hit to PF00899, ThiF family
257309000225	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309000226	ProfileScan hit to PS50205, NAD binding site.
257309000227	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309000228	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
257309000229	dimer interface [polypeptide binding]; other site
257309000230	substrate binding site [chemical binding]; other site
257309000231	ATP binding site [chemical binding]; other site
257309000232	CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI; Region: cas_Csn1; TIGR01865
257309000233	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
257309000234	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
257309000235	HMMSmart hit to SM00507, HNH nucleases
257309000236	HMMPfam hit to PF01844, HNH endonuclease
257309000237	Predicted helix-turn-helix motif with score 1063 (+2.81 SD) at aa 663-684, sequence RSMESVAWMANELRSRVAQHFA
257309000238	CRISPR/Cas system-associated protein Cas1; Region: Cas1_II; cd09720
257309000239	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cl11442
257309000240	Pseudogene. Similar to Corynebacterium diphtheriae probable transposase for insertion sequence element SW:TRA_CORDI (P35879) (343 aa) fasta scores: E(): 6e-75, 61.11% id in 342 aa. Note: Also similar to DIP2026 to DIP2029 also a pseudogene (274 aa). Presents frameshifts at positions: 37, 107, 139 and 247; transposase for insertion sequence element (pseudogene)
257309000241	HMMPfam hit to PF00872, Transposase, Mutator family
257309000242	HMMPfam hit to PF00872, Transposase, Mutator family
257309000243	HMMPfam hit to PF00872, Transposase, Mutator family
257309000244	Transposase [DNA replication, recombination, and repair]; Region: COG5421
257309000245	HMMPfam hit to PF01609, Transposase (IS4 family)
257309000246	Integrase core domain; Region: rve_3; cl15866
257309000247	HMMPfam hit to PF00665, Integrase core domain
257309000248	putative septation inhibitor protein; Reviewed; Region: PRK00159
257309000249	2 probable transmembrane helices predicted for DIP0052 by TMHMM2.0
257309000250	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
257309000251	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
257309000252	active site
257309000253	ATP binding site [chemical binding]; other site
257309000254	substrate binding site [chemical binding]; other site
257309000255	activation loop (A-loop); other site
257309000256	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
257309000257	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309000258	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309000259	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309000260	PASTA domain; Region: PASTA; pfam03793
257309000261	2 probable transmembrane helices predicted for DIP0053 by TMHMM2.0
257309000262	HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain; ProfileScan hit to PS50011, Protein kinase domain profile.
257309000263	HMMSmart hit to SM00219, Tyrosine kinase, catalytic domain
257309000264	HMMPfam hit to PF00069, Protein kinase domain
257309000265	ScanRegExp hit to PS00108, Serine/Threonine protein kinases active-site signature.
257309000266	ScanRegExp hit to PS00107, Protein kinases ATP-binding region signature.
257309000267	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
257309000268	Catalytic domain of Protein Kinases; Region: PKc; cd00180
257309000269	active site
257309000270	ATP binding site [chemical binding]; other site
257309000271	substrate binding site [chemical binding]; other site
257309000272	activation loop (A-loop); other site
257309000273	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
257309000274	ProfileScan hit to PS50099, Proline-rich region.
257309000275	FPrintScan hit to PR01217, Proline rich extensin signature
257309000276	FPrintScan hit to PR01217, Proline rich extensin signature
257309000277	FPrintScan hit to PR01217, Proline rich extensin signature
257309000278	FPrintScan hit to PR01217, Proline rich extensin signature
257309000279	ProfileScan hit to PS50011, Protein kinase domain profile.
257309000280	HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain
257309000281	HMMSmart hit to SM00219, Tyrosine kinase, catalytic domain
257309000282	HMMPfam hit to PF00069, Protein kinase domain
257309000283	ScanRegExp hit to PS00108, Serine/Threonine protein kinases active-site signature.
257309000284	ScanRegExp hit to PS00107, Protein kinases ATP-binding region signature.
257309000285	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
257309000286	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
257309000287	HMMPfam hit to PF00905, Penicillin binding protein transpeptidase domain
257309000288	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
257309000289	HMMPfam hit to PF01098, Cell cycle protein
257309000290	12 probable transmembrane helices predicted for DIP0056 by TMHMM2.0
257309000291	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
257309000292	Protein phosphatase 2C; Region: PP2C; pfam00481
257309000293	active site
257309000294	1 probable transmembrane helix predicted for DIP0057 by TMHMM2.0
257309000295	ProfileScan hit to PS50170, Protein phosphatase 2C, box 2.
257309000296	HMMSmart hit to SM00331, Sigma factor PP2C-like phosphatases
257309000297	HMMSmart hit to SM00332, Serine/threonine phosphatases, family 2C, catalytic domain
257309000298	HMMPfam hit to PF00481, Protein phosphatase 2C
257309000299	BlastProDom hit to PD006823, PD006823
257309000300	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
257309000301	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
257309000302	phosphopeptide binding site; other site
257309000303	HMMPfam hit to PF00498, FHA domain
257309000304	HMMSmart hit to SM00240, Forkhead associated domain
257309000305	ProfileScan hit to PS50006, Forkhead-associated (FHA) domain profile.
257309000306	Protein of unknown function (DUF2662); Region: DUF3662; pfam12401
257309000307	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
257309000308	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
257309000309	phosphopeptide binding site; other site
257309000310	HMMPfam hit to PF00498, FHA domain
257309000311	HMMSmart hit to SM00240, Forkhead associated domain
257309000312	ProfileScan hit to PS50006, Forkhead-associated (FHA) domain profile.
257309000313	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309000314	Pseudogene. Similar to Corynebacterium glutamicum IS1628 transposase TnpB TR:Q9X542 (EMBL:AF121000) (236 aa) fasta scores: E(): 9e-47, 86.923% id in 130 aa. Presents frameshifts at residues 18 and 62;IS1628 transposase (pseudogene)
257309000315	Anomalous G+C content (63.8%) and dinucleotide signature.  metal transport system. Present also in C.glutamicum
257309000316	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
257309000317	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
257309000318	Soluble P-type ATPase [General function prediction only]; Region: COG4087
257309000319	8 probable transmembrane helices predicted for DIP0061 by TMHMM2.0
257309000320	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309000321	FPrintScan hit to PR00120, H+-transporting ATPase (proton pump) signature
257309000322	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309000323	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309000324	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309000325	FPrintScan hit to PR00120, H+-transporting ATPase (proton pump) signature
257309000326	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309000327	FPrintScan hit to PR00120, H+-transporting ATPase (proton pump) signature
257309000328	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309000329	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309000330	ProfileScan hit to PS50310, Alanine-rich region.
257309000331	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309000332	ScanRegExp hit to PS00154, E1-E2 ATPases phosphorylation site.
257309000333	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309000334	HMMPfam hit to PF00122, E1-E2 ATPase
257309000335	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309000336	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309000337	ScanRegExp hit to PS01039, Bacterial extracellular solute-binding proteins, family 3 signature.
257309000338	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309000339	ProfileScan hit to PS50316, Histidine-rich region.
257309000340	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
257309000341	metal-binding site [ion binding]
257309000342	HMMPfam hit to PF00403, Heavy-metal-associated domain
257309000343	ScanRegExp hit to PS01047, Heavy-metal-associated domain.
257309000344	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
257309000345	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
257309000346	dimerization interface [polypeptide binding]; other site
257309000347	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
257309000348	dimer interface [polypeptide binding]; other site
257309000349	phosphorylation site [posttranslational modification]
257309000350	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309000351	ATP binding site [chemical binding]; other site
257309000352	Mg2+ binding site [ion binding]; other site
257309000353	G-X-G motif; other site
257309000354	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309000355	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309000356	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309000357	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309000358	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309000359	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309000360	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain; HMMSmart hit to SM00388, His Kinase A (phosphoacceptor) domain
257309000361	HMMSmart hit to SM00304, HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
257309000362	HMMPfam hit to PF00672, HAMP domain
257309000363	2 probable transmembrane helices predicted for DIP0063 by TMHMM2.0
257309000364	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
257309000365	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309000366	active site
257309000367	phosphorylation site [posttranslational modification]
257309000368	intermolecular recognition site; other site
257309000369	dimerization interface [polypeptide binding]; other site
257309000370	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
257309000371	DNA binding site [nucleotide binding]
257309000372	HMMPfam hit to PF00486, Transcriptional regulatory protein, C terminal
257309000373	HMMPfam hit to PF00072, Response regulator receiver domain
257309000374	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309000375	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309000376	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
257309000377	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
257309000378	Multicopper oxidase; Region: Cu-oxidase; pfam00394
257309000379	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
257309000380	Potential twin-arginine recognition motif RRQFLL
257309000381	HMMPfam hit to PF00394, Multicopper oxidase
257309000382	ScanRegExp hit to PS00079, Multicopper oxidases signature 1.
257309000383	HMMPfam hit to PF00394, Multicopper oxidase
257309000384	ScanRegExp hit to PS00215, Mitochondrial energy transfer proteins signature.
257309000385	HMMPfam hit to PF00394, Multicopper oxidase
257309000386	ScanRegExp hit to PS00079, Multicopper oxidases signature 1.
257309000387	ScanRegExp hit to PS00080, Multicopper oxidases signature 2.
257309000388	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
257309000389	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
257309000390	Pseudogene. Similar to Corynebacterium striatum transposase Tnp1250A or Tnp1250B TR:Q9ET89 (EMBL:AF024666) (416 aa) fasta scores: E(): 1.3e-143, 88.38% id in 396 aa. Presents a frameshift at residue 244;transposase (pseudogene)
257309000391	HMMPfam hit to PF00872, Transposase, Mutator family
257309000392	HMMPfam hit to PF00872, Transposase, Mutator family
257309000393	ScanRegExp hit to PS01007, Transposases, Mutator family, signature.
257309000394	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309000395	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
257309000396	1 probable transmembrane helix predicted for DIP0084 by TMHMM2.0
257309000397	4 probable transmembrane helices predicted for DIP0085 by TMHMM2.0
257309000398	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
257309000399	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309000400	non-specific DNA binding site [nucleotide binding]; other site
257309000401	salt bridge; other site
257309000402	sequence-specific DNA binding site [nucleotide binding]; other site
257309000403	HMMSmart hit to SM00530, Helix-turn-helix XRE-family like proteins, DNA-binding
257309000404	HMMPfam hit to PF01381, Helix-turn-helix
257309000405	Predicted helix-turn-helix motif with score 1845 (+5.47 SD) at aa 36-57, sequence MSRAQLAELVDVNPQTIGALER
257309000406	Pseudogene. Similar to Pseudomonas chlororaphis phenazine biosynthesis protein PhzF or PhzC SW:PHZF_PSECL (Q51520) (278 aa) fasta scores: E(): 1.1e-11, 32.92% id in 246 aa, and to Pseudomonas fluorescens phenazine biosynthesis protein PhzF SW:PHZF_PSEFL (Q51792) (278 aa) fasta scores: E(): 1.8e-11, 32.38% id in 247 aa. Presents a frameshift at residue 109; antibiotic production protein (pseudogene)
257309000407	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732
257309000408	10 probable transmembrane helices predicted for DIP0089 by TMHMM2.0
257309000409	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
257309000410	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
257309000411	Walker A/P-loop; other site
257309000412	ATP binding site [chemical binding]; other site
257309000413	Q-loop/lid; other site
257309000414	ABC transporter signature motif; other site
257309000415	Walker B; other site
257309000416	D-loop; other site
257309000417	H-loop/switch region; other site
257309000418	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000419	HMMPfam hit to PF00005, ABC transporter
257309000420	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000421	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000422	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000423	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000424	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
257309000425	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309000426	active site
257309000427	phosphorylation site [posttranslational modification]
257309000428	intermolecular recognition site; other site
257309000429	dimerization interface [polypeptide binding]; other site
257309000430	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
257309000431	DNA binding residues [nucleotide binding]
257309000432	dimerization interface [polypeptide binding]; other site
257309000433	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family
257309000434	HMMSmart hit to SM00421, helix_turn_helix, Lux Regulon
257309000435	ProfileScan hit to PS50043, Helix-turn-helix domain, luxR and related types (substantial overlap with lysR type).
257309000436	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309000437	ScanRegExp hit to PS00622, Bacterial regulatory proteins, luxR family signature.
257309000438	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309000439	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309000440	HMMPfam hit to PF00072, Response regulator receiver domain
257309000441	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309000442	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309000443	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
257309000444	Histidine kinase; Region: HisKA_3; pfam07730
257309000445	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
257309000446	6 probable transmembrane helices predicted for DIP0092 by TMHMM2.0
257309000447	ScanRegExp hit to PS00133, Zinc carboxypeptidases, zinc-binding region 2 signature.
257309000448	ProfileScan hit to PS50326, Valine-rich region.
257309000449	3 probable transmembrane helices predicted for DIP0093 by TMHMM2.0
257309000450	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
257309000451	5 probable transmembrane helices predicted for DIP0095 by TMHMM2.0
257309000452	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309000453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309000454	dimer interface [polypeptide binding]; other site
257309000455	conserved gate region; other site
257309000456	putative PBP binding loops; other site
257309000457	ABC-ATPase subunit interface; other site
257309000458	5 probable transmembrane helices predicted for DIP0096 by TMHMM2.0
257309000459	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309000460	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
257309000461	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
257309000462	Walker A/P-loop; other site
257309000463	ATP binding site [chemical binding]; other site
257309000464	Q-loop/lid; other site
257309000465	ABC transporter signature motif; other site
257309000466	Walker B; other site
257309000467	D-loop; other site
257309000468	H-loop/switch region; other site
257309000469	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000470	HMMPfam hit to PF00005, ABC transporter
257309000471	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000472	ScanRegExp hit to PS00211, ABC transporters family signature.
257309000473	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000474	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000475	Anti-sigma-K factor rskA; Region: RskA; pfam10099
257309000476	1 probable transmembrane helix predicted for DIP0098 by TMHMM2.0
257309000477	RNA polymerase sigma factor SigK; Reviewed; Region: PRK09646
257309000478	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309000479	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309000480	DNA binding residues [nucleotide binding]
257309000481	Predicted helix-turn-helix motif with score 1081 (+2.87 SD) at aa 152-173, sequence LTHSEIAEATGVPLGTAKTRLR
257309000482	HMMPfam hit to PF00776, Sigma-70 factor (ECF subfamily)
257309000483	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
257309000484	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
257309000485	TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; Region: TlpA_like_DipZ_like; cd03012
257309000486	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
257309000487	catalytic residues [active]
257309000488	HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembrane region
257309000489	6 probable transmembrane helices predicted for DIP0101 by TMHMM2.0
257309000490	ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).
257309000491	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
257309000492	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
257309000493	DNA binding residues [nucleotide binding]
257309000494	dimer interface [polypeptide binding]; other site
257309000495	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
257309000496	HMMSmart hit to SM00422, helix_turn_helix, mercury resistance
257309000497	FPrintScan hit to PR00040, MerR bacterial regulatory protein HTH signature
257309000498	HMMPfam hit to PF00376, Bacterial regulatory proteins, merR family
257309000499	ScanRegExp hit to PS00552, Bacterial regulatory proteins, merR family signature.
257309000500	FPrintScan hit to PR00040, MerR bacterial regulatory protein HTH signature
257309000501	Predicted helix-turn-helix motif with score 1580 (+4.57 SD) at aa 11-32, sequence RTVGEVADLVGVSVRTLHHWDD
257309000502	FPrintScan hit to PR00040, MerR bacterial regulatory protein HTH signature
257309000503	MT0933-like antitoxin protein; Region: MT0933_antitox; pfam14013
257309000504	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
257309000505	M20 Peptidase, carboxypeptidase yscS-like; Region: M20_yscS_like; cd05675
257309000506	putative metal binding site [ion binding]; other site
257309000507	HMMPfam hit to PF01546, Peptidase M20/M25/M40
257309000508	biotin synthase; Validated; Region: PRK06256
257309000509	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309000510	FeS/SAM binding site; other site
257309000511	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
257309000512	HMMPfam hit to PF01792, Biotin synthase
257309000513	Anomalous G+C content (56.29%). DtxR-regulated operon siderophore-dependent iron uptake system. Not present in C.glutamicum
257309000514	DtxR-regulated promoter/operator
257309000515	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
257309000516	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
257309000517	putative ligand binding residues [chemical binding]; other site
257309000518	HMMPfam hit to PF01497, Periplasmic binding protein
257309000519	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309000520	ABC-ATPase subunit  interface; other site
257309000521	dimer interface [polypeptide binding]; other site
257309000522	putative PBP binding regions; other site
257309000523	9 probable transmembrane helices predicted for DIP0109 by TMHMM2.0
257309000524	HMMPfam hit to PF01032, FecCD transport family
257309000525	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309000526	ProfileScan hit to PS50281, Binding-system dependent bacterial transporters (araH, livH/limM families)
257309000527	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
257309000528	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
257309000529	Walker A/P-loop; other site
257309000530	ATP binding site [chemical binding]; other site
257309000531	Q-loop/lid; other site
257309000532	ABC transporter signature motif; other site
257309000533	Walker B; other site
257309000534	D-loop; other site
257309000535	H-loop/switch region; other site
257309000536	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000537	HMMPfam hit to PF00005, ABC transporter
257309000538	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000539	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000540	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000541	ScanRegExp hit to PS00211, ABC transporters family signature.
257309000542	ScanRegExp hit to PS00430, TonB-dependent receptor proteins signature 1.
257309000543	Uncharacterized conserved protein [Function unknown]; Region: COG5646
257309000544	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
257309000545	DNA photolyase; Region: DNA_photolyase; pfam00875
257309000546	HMMPfam hit to PF00875, DNA photolyase
257309000547	FPrintScan hit to PR00147, DNA photolyase signature
257309000548	BlastProDom hit to PD004390, PD004390
257309000549	FPrintScan hit to PR00147, DNA photolyase signature
257309000550	FPrintScan hit to PR00147, DNA photolyase signature
257309000551	FPrintScan hit to PR00147, DNA photolyase signature
257309000552	Protein of unknown function (DUF2871); Region: DUF2871; pfam11070
257309000553	4 probable transmembrane helices predicted for DIP0114 by TMHMM2.0
257309000554	Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260
257309000555	Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; cl00554
257309000556	HMMPfam hit to PF01658, Myo-inositol-1-phosphate synthase
257309000557	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
257309000558	5 probable transmembrane helices predicted for DIP0116 by TMHMM2.0
257309000559	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
257309000560	Lipase (class 2); Region: Lipase_2; pfam01674
257309000561	HMMPfam hit to PF01674, Lipase (class 2)
257309000562	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309000563	NADPH_oxidase. Nitroreductase family containing NADH oxidase and other, uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles; Region: NADH_oxidase; cd03370
257309000564	dimer interface [polypeptide binding]; other site
257309000565	FMN binding site [chemical binding]; other site
257309000566	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
257309000567	Divergent AAA domain; Region: AAA_4; pfam04326
257309000568	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
257309000569	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
257309000570	Sugar-specific transcriptional regulator TrmB; Region: TrmB; cl17775
257309000571	Predicted helix-turn-helix motif with score 1072 (+2.84 SD) at aa 531-552, sequence ISAAEIAESIGMPRPEITEILR
257309000572	Pseudogene. Highly similar to the N-terminal region of Corynebacterium xerosis and Corynebacterium striatum hypothetical 20.7 kDa protein TnpCX TR:Q46485 (EMBL:U21300) (190 aa) fasta scores: E(): 0.057, 63.41% id in 41 aa. Presents a frameshift at residue 17; transposon (pseudogene)
257309000573	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
257309000574	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
257309000575	trimer interface [polypeptide binding]; other site
257309000576	putative metal binding site [ion binding]; other site
257309000577	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000578	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000579	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000580	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000581	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
257309000582	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
257309000583	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
257309000584	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
257309000585	5 probable transmembrane helices predicted for DIP0124 by TMHMM2.0
257309000586	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
257309000587	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
257309000588	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309000589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4805
257309000590	Transcriptional regulators [Transcription]; Region: MarR; COG1846
257309000591	MarR family; Region: MarR; pfam01047
257309000592	HMMSmart hit to SM00347, helix_turn_helix multiple antibiotic resistance protein, DNA-binding
257309000593	HMMPfam hit to PF01047, MarR family
257309000594	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309000595	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309000596	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309000597	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
257309000598	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
257309000599	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
257309000600	10 probable transmembrane helices predicted for DIP0128 by TMHMM2.0
257309000601	hypothetical protein; Provisional; Region: PRK10621
257309000602	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
257309000603	7 probable transmembrane helices predicted for DIP0130 by TMHMM2.0
257309000604	HMMPfam hit to PF01925, Domain of unknown function DUF81
257309000605	HMMPfam hit to PF01925, Domain of unknown function DUF81
257309000606	HrpA-like helicases [DNA replication, recombination, and repair]; Region: HrpA; COG1643
257309000607	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309000608	ATP binding site [chemical binding]; other site
257309000609	putative Mg++ binding site [ion binding]; other site
257309000610	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309000611	nucleotide binding region [chemical binding]; other site
257309000612	Helicase associated domain (HA2); Region: HA2; pfam04408
257309000613	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
257309000614	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309000615	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309000616	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309000617	ScanRegExp hit to PS00690, DEAH-box subfamily ATP-dependent helicases signature.
257309000618	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000619	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
257309000620	maltose O-acetyltransferase; Provisional; Region: PRK10092
257309000621	active site
257309000622	substrate binding site [chemical binding]; other site
257309000623	trimer interface [polypeptide binding]; other site
257309000624	CoA binding site [chemical binding]; other site
257309000625	ScanRegExp hit to PS00101, Hexapeptide-repeat containing-transferases signature.
257309000626	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000627	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000628	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000629	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309000630	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
257309000631	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
257309000632	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
257309000633	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
257309000634	NAD(P) binding site [chemical binding]; other site
257309000635	active site
257309000636	HMMPfam hit to PF00106, short chain dehydrogenase
257309000637	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000638	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309000639	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature; FPrintScan hit to PR00080, Short-chain dehydrogenase/reductase (SDR) superfamily signature
257309000640	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309000641	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000642	FPrintScan hit to PR00080, Short-chain dehydrogenase/reductase (SDR) superfamily signature
257309000643	ScanRegExp hit to PS00061, Short-chain dehydrogenases/reductases family signature.
257309000644	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature; FPrintScan hit to PR00080, Short-chain dehydrogenase/reductase (SDR) superfamily signature
257309000645	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309000646	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000647	2 probable transmembrane helices predicted for DIP0139 by TMHMM2.0
257309000648	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
257309000649	Pseudogene. Similar to Mycobacterium tuberculosis CDC1551 IS1603, transposase MT3281 TR:AAK47622 (EMBL:AE007140) (344 aa) fasta scores: E(): 2.1e-42, 40.65% id in 337 aa. Presents frameshifts at residues 36 and 242; transposase (pseudogene)
257309000650	BlastProDom hit to PD002997, PD002997
257309000651	HMMPfam hit to PF00665, Integrase core domain
257309000652	BlastProDom hit to PD002997, PD002997
257309000653	HMMPfam hit to PF00665, Integrase core domain
257309000654	SdpI/YhfL protein family; Region: SdpI; pfam13630
257309000655	3 probable transmembrane helices predicted for DIP0146 by TMHMM2.0
257309000656	1 probable transmembrane helix predicted for DIP0147 by TMHMM2.0
257309000657	Pseudogene. Similar to the plasmid borne Corynebacterium striatum YtpG TR:Q9FB50 (EMBL:AF024666) (76 aa) fasta scores: E(): 3.2e-09, 78.46% id in 65 aa. Presents a frameshift at residue 50;Conserved hypothetical protein (pseudogene)
257309000658	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
257309000659	RNA binding surface [nucleotide binding]; other site
257309000660	HMMPfam hit to PF01479, S4 domain
257309000661	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
257309000662	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
257309000663	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
257309000664	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
257309000665	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
257309000666	active site
257309000667	DNA binding site [nucleotide binding]
257309000668	HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferase, DNA binding domain
257309000669	Predicted helix-turn-helix motif with score 1011 (+2.63 SD) at aa 31-52, sequence TTYGDIARRVGCGARHVGSIMR
257309000670	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
257309000671	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
257309000672	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
257309000673	active site
257309000674	Zn binding site [ion binding]; other site
257309000675	HMMPfam hit to PF01431, Peptidase M13
257309000676	FPrintScan hit to PR00786, Neprilysin metalloprotease (M13) family signature
257309000677	FPrintScan hit to PR00786, Neprilysin metalloprotease (M13) family signature
257309000678	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309000679	FPrintScan hit to PR00786, Neprilysin metalloprotease (M13) family signature
257309000680	FPrintScan hit to PR00786, Neprilysin metalloprotease (M13) family signature
257309000681	Protease prsW family; Region: PrsW-protease; pfam13367
257309000682	8 probable transmembrane helices predicted for DIP0156 by TMHMM2.0
257309000683	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
257309000684	Mycobacterial cell wall arabinan synthesis protein; Region: Arabinose_trans; pfam04602
257309000685	13 probable transmembrane helices predicted for DIP0159 by TMHMM2.0
257309000686	Arabinofuranosyltransferase N terminal; Region: AftA_N; pfam12250
257309000687	Arabinofuranosyltransferase A C terminal; Region: AftA_C; pfam12249
257309000688	11 probable transmembrane helices predicted for DIP0160 by TMHMM2.0
257309000689	ScanRegExp hit to PS00237, G-protein coupled receptors family 1 signature.
257309000690	short chain dehydrogenase; Provisional; Region: PRK07904
257309000691	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
257309000692	NAD(P) binding site [chemical binding]; other site
257309000693	active site
257309000694	HMMPfam hit to PF00106, short chain dehydrogenase
257309000695	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000696	FPrintScan hit to PR01167, Insect alcohol dehydrogenase signature
257309000697	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000698	FPrintScan hit to PR01167, Insect alcohol dehydrogenase signature
257309000699	ScanRegExp hit to PS00061, Short-chain dehydrogenases/reductases family signature.
257309000700	FPrintScan hit to PR01167, Insect alcohol dehydrogenase signature
257309000701	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000702	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000703	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309000704	FPrintScan hit to PR01167, Insect alcohol dehydrogenase signature
257309000705	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
257309000706	FAD binding domain; Region: FAD_binding_4; pfam01565
257309000707	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
257309000708	HMMPfam hit to PF01565, FAD binding domain
257309000709	3 probable transmembrane helices predicted for DIP0164 by TMHMM2.0
257309000710	Predicted membrane protein [Function unknown]; Region: COG2246
257309000711	GtrA-like protein; Region: GtrA; pfam04138
257309000712	4 probable transmembrane helices predicted for DIP0166 by TMHMM2.0
257309000713	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
257309000714	putative active site [active]
257309000715	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
257309000716	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
257309000717	active site
257309000718	HMMPfam hit to PF00535, Glycosyl transferase
257309000719	ProfileScan hit to PS50167, General Glycosyltransferase domain.
257309000720	Anomalous G+C content (57.26%) and GC deviation. metal transport system
257309000721	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309000722	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
257309000723	intersubunit interface [polypeptide binding]; other site
257309000724	Potential twin-arginine recognition motif RRGFIR
257309000725	HMMPfam hit to PF01297, Periplasmic solute binding protein family
257309000726	FPrintScan hit to PR00691, Adhesin B signature
257309000727	FPrintScan hit to PR00690, Adhesin family signature
257309000728	FPrintScan hit to PR00691, Adhesin B signature
257309000729	FPrintScan hit to PR00690, Adhesin family signature
257309000730	FPrintScan hit to PR00691, Adhesin B signature
257309000731	FPrintScan hit to PR00690, Adhesin family signature
257309000732	FPrintScan hit to PR00691, Adhesin B signature
257309000733	FPrintScan hit to PR00690, Adhesin family signature
257309000734	FPrintScan hit to PR00691, Adhesin B signature
257309000735	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
257309000736	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
257309000737	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000738	HMMPfam hit to PF00005, ABC transporter
257309000739	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000740	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000741	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000742	ScanRegExp hit to PS00211, ABC transporters family signature.
257309000743	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
257309000744	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309000745	ABC-ATPase subunit  interface; other site
257309000746	dimer interface [polypeptide binding]; other site
257309000747	putative PBP binding regions; other site
257309000748	HMMPfam hit to PF00950, ABC 3 transport family
257309000749	8 probable transmembrane helices predicted for DIP0171 by TMHMM2.0
257309000750	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
257309000751	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309000752	ABC-ATPase subunit  interface; other site
257309000753	dimer interface [polypeptide binding]; other site
257309000754	putative PBP binding regions; other site
257309000755	HMMPfam hit to PF00950, ABC 3 transport family
257309000756	8 probable transmembrane helices predicted for DIP0172 by TMHMM2.0
257309000757	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309000758	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
257309000759	intersubunit interface [polypeptide binding]; other site
257309000760	HMMPfam hit to PF01297, Periplasmic solute binding protein family
257309000761	FPrintScan hit to PR00691, Adhesin B signature
257309000762	FPrintScan hit to PR00690, Adhesin family signature
257309000763	FPrintScan hit to PR00690, Adhesin family signature
257309000764	FPrintScan hit to PR00690, Adhesin family signature
257309000765	ProfileScan hit to PS50316, Histidine-rich region.
257309000766	FPrintScan hit to PR00691, Adhesin B signature
257309000767	O-antigen export system
257309000768	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
257309000769	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
257309000770	Walker A/P-loop; other site
257309000771	ATP binding site [chemical binding]; other site
257309000772	Q-loop/lid; other site
257309000773	ABC transporter signature motif; other site
257309000774	Walker B; other site
257309000775	D-loop; other site
257309000776	H-loop/switch region; other site
257309000777	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000778	HMMPfam hit to PF00005, ABC transporter
257309000779	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309000780	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309000781	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000782	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
257309000783	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
257309000784	HMMPfam hit to PF01061, ABC-2 type transporter
257309000785	6 probable transmembrane helices predicted for DIP0175 by TMHMM2.0
257309000786	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
257309000787	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
257309000788	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
257309000789	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
257309000790	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
257309000791	NAD(P) binding site [chemical binding]; other site
257309000792	HMMPfam hit to PF00107, Zinc-binding dehydrogenases
257309000793	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
257309000794	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309000795	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309000796	homodimer interface [polypeptide binding]; other site
257309000797	catalytic residue [active]
257309000798	HMMPfam hit to PF00155, Aminotransferase class I and II
257309000799	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309000800	ScanRegExp hit to PS00599, Aminotransferases class-II pyridoxal-phosphate attachment site.
257309000801	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309000802	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
257309000803	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
257309000804	transmembrane helices; other site
257309000805	14 probable transmembrane helices predicted for DIP0179 by TMHMM2.0
257309000806	HMMPfam hit to PF00939, Sodium:sulfate symporter transmembrane region
257309000807	Corynephage
257309000808	Protein of unknown function (DUF3644); Region: DUF3644; pfam12358
257309000809	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
257309000810	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
257309000811	active site
257309000812	catalytic residues [active]
257309000813	DNA binding site [nucleotide binding]
257309000814	Int/Topo IB signature motif; other site
257309000815	HMMPfam hit to PF00589, Phage integrase
257309000816	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309000817	sequence-specific DNA binding site [nucleotide binding]; other site
257309000818	salt bridge; other site
257309000819	Domain of unknown function (DUF955); Region: DUF955; cl01076
257309000820	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309000821	HMMSmart hit to SM00530, Helix-turn-helix XRE-family like proteins, DNA-binding
257309000822	HMMPfam hit to PF01381, Helix-turn-helix
257309000823	Predicted helix-turn-helix motif with score 2114 (+6.39 SD) at aa 17-38, sequence RSQGEFAEQLGIAQSTLSSVER
257309000824	Domain of unknown function (DUF955); Region: DUF955; pfam06114
257309000825	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309000826	non-specific DNA binding site [nucleotide binding]; other site
257309000827	salt bridge; other site
257309000828	sequence-specific DNA binding site [nucleotide binding]; other site
257309000829	HMMSmart hit to SM00530, Helix-turn-helix XRE-family like proteins, DNA-binding
257309000830	HMMPfam hit to PF01381, Helix-turn-helix
257309000831	Prophage antirepressor [Transcription]; Region: COG3617
257309000832	BRO family, N-terminal domain; Region: Bro-N; smart01040
257309000833	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
257309000834	HMMPfam hit to PF02498, BRO family, N-terminus
257309000835	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000836	ProfileScan hit to PS50310, Alanine-rich region.
257309000837	ProfileScan hit to PS50323, Arginine-rich region.
257309000838	HMMSmart hit to SM00507, HNH nucleases
257309000839	Pseudogene. Similar to Bacteriophage BFK20 hypothetical 75.6 kDa protein TR:Q9MBK4 (EMBL:AJ278322) (679 aa) fasta scores: E(): 6e-79, 40.76% id in 677 aa. Presents a frameshift at residue 117; phage terminase (pseudogene)
257309000840	ProfileScan hit to PS50312, Aspartic acid-rich region.
257309000841	Phage-related protein [Function unknown]; Region: COG4695; cl01923
257309000842	Phage portal protein; Region: Phage_portal; pfam04860
257309000843	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
257309000844	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000845	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
257309000846	Phage capsid family; Region: Phage_capsid; pfam05065
257309000847	ScanRegExp hit to PS00430, TonB-dependent receptor proteins signature 1.
257309000848	Phage-related minor tail protein [Function unknown]; Region: COG5280
257309000849	ProfileScan hit to PS50310, Alanine-rich region.
257309000850	4 probable transmembrane helices predicted for DIP0212 by TMHMM2.0
257309000851	ProfileScan hit to PS50310, Alanine-rich region.
257309000852	ScanRegExp hit to PS00213, Lipocalin signature.
257309000853	ProfileScan hit to PS50315, Glycine-rich region.
257309000854	ProfileScan hit to PS50315, Glycine-rich region.
257309000855	ProfileScan hit to PS50310, Alanine-rich region.
257309000856	Domain of unknown function (DUF1906); Region: DUF1906; pfam08924
257309000857	N-acetylmuramoyl-L-alanine amidase; Region: Amidase_2; pfam01510
257309000858	amidase catalytic site [active]
257309000859	Zn binding residues [ion binding]; other site
257309000860	substrate binding site [chemical binding]; other site
257309000861	2 probable transmembrane helices predicted for DIP0219 by TMHMM2.0
257309000862	4 probable transmembrane helices predicted for DIP0220 by TMHMM2.0
257309000863	tox promoter, DtxR-regulated
257309000864	ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell; Region: ADP_ribosyl; cd01341
257309000865	nad+ binding pocket [chemical binding]; other site
257309000866	Diphtheria toxin, T domain; Region: Diphtheria_T; pfam02764
257309000867	Diphtheria toxin, R domain; Region: Diphtheria_R; pfam01324
257309000868	BlastProDom hit to PD025441, PD025441
257309000869	HMMPfam hit to PF02763, Diphtheria toxin, C domain
257309000870	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000871	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000872	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000873	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000874	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000875	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000876	HMMPfam hit to PF02764, Diphtheria toxin, T domain
257309000877	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000878	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000879	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000880	FPrintScan hit to PR00769, Diphtheria toxin signature
257309000881	HMMPfam hit to PF01324, Diphtheria toxin, R domain
257309000882	Anomalous G+C content (56.92%) and G/C deviation. pathogenicity island. Not present in C.glutamicum
257309000883	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
257309000884	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
257309000885	HMMPfam hit to PF01522, Polysaccharide deacetylase
257309000886	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
257309000887	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309000888	DNA-binding site [nucleotide binding]; DNA binding site
257309000889	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309000890	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309000891	homodimer interface [polypeptide binding]; other site
257309000892	catalytic residue [active]
257309000893	ScanRegExp hit to PS00758, ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
257309000894	ProfileScan hit to PS50099, Proline-rich region.
257309000895	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family; HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309000896	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309000897	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309000898	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309000899	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
257309000900	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
257309000901	active site
257309000902	multimer interface [polypeptide binding]; other site
257309000903	BlastProDom hit to PD004958, PD004958; HMMPfam hit to PF01680, SOR/SNZ family
257309000904	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309000905	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
257309000906	predicted active site [active]
257309000907	catalytic triad [active]
257309000908	HMMPfam hit to PF01174, SNO glutamine amidotransferase
257309000909	1 probable transmembrane helix predicted for DIP0229 by TMHMM2.0
257309000910	Pseudogene. Similar to Shigella flexneri transposase for IS110 S0128 TR:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 5.4e-25, 34.75% id in 328 aa. Presents frameshifts at residues 85 and 194 and lacks stop codon;IS element transposase (pseudogene)
257309000911	This hit extended beyond the end of the feature by 1 aa and was clipped.; HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family
257309000912	ScanRegExp hit to PS00217, Sugar transport proteins signature 2.
257309000913	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
257309000914	active site
257309000915	catalytic site [active]
257309000916	2 probable transmembrane helices predicted for DIP0233 by TMHMM2.0
257309000917	Cna protein B-type domain; Region: Cna_B; pfam05738
257309000918	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
257309000919	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309000920	potential sortase anchor site LPMTG
257309000921	1 probable transmembrane helix predicted for DIP0235 by TMHMM2.0
257309000922	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
257309000923	active site
257309000924	catalytic site [active]
257309000925	2 probable transmembrane helices predicted for DIP0236 by TMHMM2.0
257309000926	ProfileScan hit to PS50099, Proline-rich region.
257309000927	potential sortase anchor site LALTG
257309000928	probable transmembrane helix predicted for DIP0237 by TMHMM2.0
257309000929	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
257309000930	metal ion-dependent adhesion site (MIDAS); other site
257309000931	ProfileScan hit to PS50099, Proline-rich region.
257309000932	ScanRegExp hit to PS00678, Trp-Asp (WD) repeats signature.
257309000933	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309000934	potential sortase anchor site LPKTG
257309000935	probable transmembrane helix predicted for DIP0238 by TMHMM2.0
257309000936	Pseudogene. No database matches. Note: Contains a potential sortase anchor site (LPSTG). Presents a frameshift at residue 125; surface-anchored protein (pseudogene)
257309000937	potential sortase anchor site LPSTG
257309000938	1 probable transmembrane helix predicted for DIP0239 by TMHMM2.0
257309000939	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
257309000940	prephenate dehydrogenase; Validated; Region: PRK08507
257309000941	HMMPfam hit to PF02153, Prephenate dehydrogenase
257309000942	putative tRNA adenosine deaminase-associated protein; Region: tRNA_deam_assoc; TIGR03941
257309000943	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase zinc-binding region
257309000944	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
257309000945	nucleoside/Zn binding site; other site
257309000946	dimer interface [polypeptide binding]; other site
257309000947	catalytic motif [active]
257309000948	ScanRegExp hit to PS00903, Cytidine and deoxycytidylate deaminases zinc-binding region signature.
257309000949	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
257309000950	DNA binding residues [nucleotide binding]
257309000951	Predicted helix-turn-helix motif with score 1896 (+5.64 SD) at aa 82-103, sequence VTTQQAAELLGVSRPTVVKLIE
257309000952	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
257309000953	12 probable transmembrane helices predicted for DIP0250 by TMHMM2.0
257309000954	FPrintScan hit to PR00702, Acriflavin resistance protein family signature
257309000955	ProfileScan hit to PS50156, Sterol-sensing domain (SSD) profile.
257309000956	FPrintScan hit to PR00702, Acriflavin resistance protein family signature
257309000957	FPrintScan hit to PR00702, Acriflavin resistance protein family signature
257309000958	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
257309000959	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
257309000960	HMMPfam hit to PF01702, Queuine tRNA-ribosyltransferase
257309000961	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
257309000962	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
257309000963	active site
257309000964	HIGH motif; other site
257309000965	nucleotide binding site [chemical binding]; other site
257309000966	active site
257309000967	KMSKS motif; other site
257309000968	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q)
257309000969	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309000970	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309000971	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309000972	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309000973	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q)
257309000974	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309000975	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
257309000976	fructuronate transporter; Provisional; Region: PRK10034; cl15264
257309000977	13 probable transmembrane helices predicted for DIP0253 by TMHMM2.0
257309000978	HMMPfam hit to PF02447, GntP family permease
257309000979	Shikimate kinase; Region: SKI; pfam01202
257309000980	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
257309000981	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000982	ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309000983	Alanine-glyoxylate amino-transferase; Region: Aminotran_MocR; pfam12897
257309000984	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309000985	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309000986	homodimer interface [polypeptide binding]; other site
257309000987	catalytic residue [active]
257309000988	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
257309000989	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
257309000990	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309000991	Walker A motif; other site
257309000992	ATP binding site [chemical binding]; other site
257309000993	Walker B motif; other site
257309000994	arginine finger; other site
257309000995	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
257309000996	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309000997	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309000998	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309000999	ProfileScan hit to PS50150, Replication factor C conserved domain.
257309001000	ProfileScan hit to PS50310, Alanine-rich region.
257309001001	FPrintScan hit to PR01217, Proline rich extensin signature
257309001002	FPrintScan hit to PR01217, Proline rich extensin signature
257309001003	ProfileScan hit to PS50099, Proline-rich region.
257309001004	FPrintScan hit to PR01217, Proline rich extensin signature
257309001005	FPrintScan hit to PR01217, Proline rich extensin signature
257309001006	hypothetical protein; Validated; Region: PRK00153
257309001007	HMMPfam hit to PF02575, Uncharacterized BCR, YbaB family COG0718
257309001008	recombination protein RecR; Reviewed; Region: recR; PRK00076
257309001009	RecR protein; Region: RecR; pfam02132
257309001010	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
257309001011	putative active site [active]
257309001012	putative metal-binding site [ion binding]; other site
257309001013	tetramer interface [polypeptide binding]; other site
257309001014	HMMPfam hit to PF02132, RecR protein
257309001015	ScanRegExp hit to PS01300, RecR protein signature.
257309001016	HMMPfam hit to PF01751, Toprim domain
257309001017	HMMSmart hit to SM00493, No definition
257309001018	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
257309001019	catalytic triad [active]
257309001020	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase
257309001021	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
257309001022	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
257309001023	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
257309001024	HMMPfam hit to PF01225, Mur ligase, catalytic domain
257309001025	DNA polymerase III subunit epsilon; Validated; Region: PRK05601
257309001026	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
257309001027	active site
257309001028	catalytic site [active]
257309001029	substrate binding site [chemical binding]; other site
257309001030	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
257309001031	dimer interface [polypeptide binding]; other site
257309001032	FMN binding site [chemical binding]; other site
257309001033	NADPH bind site [chemical binding]; other site
257309001034	HMMPfam hit to PF00881, Nitroreductase
257309001035	2-isopropylmalate synthase; Validated; Region: PRK03739
257309001036	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
257309001037	active site
257309001038	catalytic residues [active]
257309001039	metal binding site [ion binding]; metal-binding site
257309001040	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
257309001041	HMMPfam hit to PF00682, HMGL-like
257309001042	ScanRegExp hit to PS00816, Alpha-isopropylmalate and homocitrate synthases signature 2.
257309001043	ScanRegExp hit to PS00815, Alpha-isopropylmalate and homocitrate synthases signature 1.
257309001044	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
257309001045	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309001046	DNA binding residues [nucleotide binding]
257309001047	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
257309001048	Predicted helix-turn-helix motif with score 2347 (+7.18 SD) at aa 52-73, sequence LGQAQVAKELGISRPTVSKLLS
257309001049	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309001050	active site
257309001051	HMMSmart hit to SM00507, HNH nucleases
257309001052	HMMPfam hit to PF01844, HNH endonuclease
257309001053	Pseudogene. Similar to Corynebacterium glutamicum DNA, transposable element IS31831 TR:Q45144 (EMBL:D17429) (436 aa) fasta scores: E(): 1.8e-14, 39.2% id in 403 aa, and to Mycobacterium smegmatis TnpA protein TR:Q50440 (EMBL:M76495) (413 aa) fasta scores: E(): 5.4e-07, 35.42% id in 223 aa. Presents internal in-frame stop codons, multiple frameshifts at residues 86, 141, 209 and 227 and lacks final stop codon; transposase (pseudogene)
257309001054	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
257309001055	HMMPfam hit to PF01048, Phosphorylase
257309001056	ScanRegExp hit to PS01232, Purine and other phosphorylases family 1 signature.
257309001057	ScanRegExp hit to PS00039, DEAD-box subfamily ATP-dependent helicases signature.
257309001058	Major Facilitator Superfamily; Region: MFS_1; pfam07690
257309001059	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309001060	putative substrate translocation pore; other site
257309001061	HMMPfam hit to PF00083, Sugar (and other) transporter
257309001062	13 probable transmembrane helices predicted for DIP0272 by TMHMM2.0
257309001063	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309001064	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309001065	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309001066	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309001067	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309001068	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309001069	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
257309001070	intersubunit interface [polypeptide binding]; other site
257309001071	active site
257309001072	catalytic residue [active]
257309001073	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase
257309001074	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309001075	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
257309001076	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
257309001077	active site
257309001078	substrate binding site [chemical binding]; other site
257309001079	metal binding site [ion binding]; metal-binding site
257309001080	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
257309001081	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309001082	ScanRegExp hit to PS00710, Phosphoglucomutase and phosphomannomutase phosphoserine signature.
257309001083	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
257309001084	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309001085	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309001086	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
257309001087	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-terminal domain
257309001088	Mannosyltransferase (PIG-V)); Region: Mannosyl_trans2; pfam04188
257309001089	8 probable transmembrane helices predicted for DIP0275 by TMHMM2.0
257309001090	9 probable transmembrane helices predicted for DIP0276 by TMHMM2.0
257309001091	aspartate kinase; Reviewed; Region: PRK06635
257309001092	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
257309001093	putative nucleotide binding site [chemical binding]; other site
257309001094	putative catalytic residues [active]
257309001095	putative Mg ion binding site [ion binding]; other site
257309001096	putative aspartate binding site [chemical binding]; other site
257309001097	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
257309001098	putative allosteric regulatory site; other site
257309001099	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
257309001100	putative allosteric regulatory residue; other site
257309001101	HMMPfam hit to PF00696, Amino acid kinase
257309001102	ScanRegExp hit to PS00324, Aspartokinase signature.
257309001103	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309001104	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309001105	HMMPfam hit to PF01842, ACT domain
257309001106	HMMPfam hit to PF01842, ACT domain
257309001107	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001108	ProfileScan hit to PS50099, Proline-rich region.
257309001109	potential sortase anchor site LARTG
257309001110	1 probable transmembrane helix predicted for DIP0278 by TMHMM2.0
257309001111	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
257309001112	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
257309001113	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD binding domain
257309001114	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisation domain
257309001115	ScanRegExp hit to PS01103, Aspartate-semialdehyde dehydrogenase signature.
257309001116	RNA polymerase sigma factor; Provisional; Region: PRK12535
257309001117	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309001118	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
257309001119	DNA binding residues [nucleotide binding]
257309001120	Predicted helix-turn-helix motif with score 1077 (+2.86 SD) at aa 150-171, sequence FSYEEAAKIADVRIGTIRSRVA
257309001121	HMMPfam hit to PF00776, Sigma-70 factor (ECF subfamily)
257309001122	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
257309001123	Catalase-like heme-binding proteins and protein domains; Region: catalase_like; cl09506
257309001124	heme binding pocket [chemical binding]; other site
257309001125	BlastProDom hit to PD000510, PD000510
257309001126	HMMPfam hit to PF00199, Catalase
257309001127	FPrintScan hit to PR00067, Catalase signature
257309001128	FPrintScan hit to PR00067, Catalase signature
257309001129	FPrintScan hit to PR00067, Catalase signature
257309001130	FPrintScan hit to PR00067, Catalase signature
257309001131	FPrintScan hit to PR00067, Catalase signature
257309001132	FPrintScan hit to PR00067, Catalase signature
257309001133	ScanRegExp hit to PS00437, Catalase proximal heme-ligand signature.
257309001134	Anomalous G+C content (55.53%), G/C deviation and dinucleotide signature.  pathogencity island. Not present in C.glutamicum
257309001135	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
257309001136	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
257309001137	Walker A/P-loop; other site
257309001138	ATP binding site [chemical binding]; other site
257309001139	Q-loop/lid; other site
257309001140	ABC transporter signature motif; other site
257309001141	Walker B; other site
257309001142	D-loop; other site
257309001143	H-loop/switch region; other site
257309001144	TOBE domain; Region: TOBE_2; pfam08402
257309001145	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309001146	HMMPfam hit to PF00005, ABC transporter
257309001147	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309001148	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309001149	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001150	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309001151	dimer interface [polypeptide binding]; other site
257309001152	conserved gate region; other site
257309001153	ABC-ATPase subunit interface; other site
257309001154	12 probable transmembrane helices predicted for DIP0283 by TMHMM2.0
257309001155	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
257309001156	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein
257309001157	Predicted helix-turn-helix motif with score 1105 (+2.95 SD) at aa 46-67, sequence QWKRDIARELGLNVRYVSLPTQ
257309001158	1 probable transmembrane helix predicted for DIP0284 by TMHMM2.0
257309001159	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
257309001160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309001161	putative substrate translocation pore; other site
257309001162	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309001163	HMMPfam hit to PF00083, Sugar (and other) transporter
257309001164	12 probable transmembrane helices predicted for DIP0285 by TMHMM2.0
257309001165	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
257309001166	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309001167	active site
257309001168	phosphorylation site [posttranslational modification]
257309001169	intermolecular recognition site; other site
257309001170	dimerization interface [polypeptide binding]; other site
257309001171	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
257309001172	DNA binding site [nucleotide binding]
257309001173	HMMPfam hit to PF00486, Transcriptional regulatory protein, C terminal
257309001174	HMMPfam hit to PF00072, Response regulator receiver domain
257309001175	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309001176	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309001177	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
257309001178	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
257309001179	dimer interface [polypeptide binding]; other site
257309001180	phosphorylation site [posttranslational modification]
257309001181	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309001182	ATP binding site [chemical binding]; other site
257309001183	Mg2+ binding site [ion binding]; other site
257309001184	G-X-G motif; other site
257309001185	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309001186	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309001187	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001188	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001189	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001190	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain; HMMSmart hit to SM00388, His Kinase A (phosphoacceptor) domain
257309001191	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309001192	1 probable transmembrane helix predicted for DIP0287 by TMHMM2.0
257309001193	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12674
257309001194	3 probable transmembrane helices predicted for DIP0288 by TMHMM2.0
257309001195	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12612
257309001196	3 probable transmembrane helices predicted for DIP0289 by TMHMM2.0
257309001197	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12654
257309001198	HMMPfam hit to PF01899, Protein of unknown function DUF68
257309001199	1 probable transmembrane helix predicted for DIP0290 by TMHMM2.0
257309001200	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK08375
257309001201	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
257309001202	14 probable transmembrane helices predicted for DIP0291 by TMHMM2.0
257309001203	HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), various chains
257309001204	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001205	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001206	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001207	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK07375
257309001208	HMMPfam hit to PF01898, Protein of unknown function DUF67
257309001209	BlastProDom hit to PD006097, PD006097
257309001210	3 probable transmembrane helices predicted for DIP0292 by TMHMM2.0
257309001211	putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12650
257309001212	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
257309001213	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
257309001214	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
257309001215	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
257309001216	23 probable transmembrane helices predicted for DIP0293 by TMHMM2.0
257309001217	FPrintScan hit to PR01434, NADH-ubiquinone oxidoreductase chain 5 signature
257309001218	HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), various chains
257309001219	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001220	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001221	FPrintScan hit to PR01434, NADH-ubiquinone oxidoreductase chain 5 signature
257309001222	FPrintScan hit to PR01434, NADH-ubiquinone oxidoreductase chain 5 signature
257309001223	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001224	FPrintScan hit to PR01434, NADH-ubiquinone oxidoreductase chain 5 signature
257309001225	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001226	FPrintScan hit to PR01437, NADH-ubiquinone oxidoreductase subunit 4 signature
257309001227	FPrintScan hit to PR01434, NADH-ubiquinone oxidoreductase chain 5 signature
257309001228	HMMPfam hit to PF00662, NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
257309001229	FPrintScan hit to PR01434, NADH-ubiquinone oxidoreductase chain 5 signature
257309001230	Predicted membrane protein [Function unknown]; Region: COG1511
257309001231	Predicted membrane protein [Function unknown]; Region: COG1511
257309001232	5 probable transmembrane helices predicted for DIP0294 by TMHMM2.0
257309001233	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
257309001234	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
257309001235	putative active site [active]
257309001236	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
257309001237	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
257309001238	putative active site [active]
257309001239	putative metal binding site [ion binding]; other site
257309001240	ProfileScan hit to PS50185, Metallo-phosphoesterase motif.
257309001241	Yqey-like protein; Region: YqeY; pfam09424
257309001242	HMMPfam hit to PF02637, GatB/Yqey domain
257309001243	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
257309001244	Transglycosylase; Region: Transgly; pfam00912
257309001245	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
257309001246	PASTA domain; Region: PASTA; pfam03793
257309001247	HMMPfam hit to PF00905, Penicillin binding protein transpeptidase domain
257309001248	HMMPfam hit to PF00912, Transglycosylase
257309001249	BlastProDom hit to PD001895, PD001895
257309001250	Transcription factor WhiB; Region: Whib; pfam02467
257309001251	HMMPfam hit to PF02467, Transcription factor WhiB
257309001252	Domain of unknown function (DUF4177); Region: DUF4177; pfam13783
257309001253	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
257309001254	homotrimer interaction site [polypeptide binding]; other site
257309001255	putative active site [active]
257309001256	HMMPfam hit to PF01042, YjgF family
257309001257	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
257309001258	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
257309001259	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily
257309001260	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
257309001261	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
257309001262	ligand binding site [chemical binding]; other site
257309001263	flexible hinge region; other site
257309001264	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
257309001265	putative switch regulator; other site
257309001266	non-specific DNA interactions [nucleotide binding]; other site
257309001267	DNA binding site [nucleotide binding]
257309001268	sequence specific DNA binding site [nucleotide binding]; other site
257309001269	putative cAMP binding site [chemical binding]; other site
257309001270	HMMSmart hit to SM00419, helix_turn_helix, cAMP Regulatory protein, DNA-binding
257309001271	HMMPfam hit to PF00325, Bacterial regulatory proteins, crp family
257309001272	Predicted helix-turn-helix motif with score 1990 (+5.96 SD) at aa 178-199, sequence LTQEEIAQLVGASRETVNKALA
257309001273	HMMSmart hit to SM00100, Cyclic nucleotide-monophosphate binding domain
257309001274	ProfileScan hit to PS50042, cAMP/cGMP binding motif.
257309001275	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain
257309001276	FPrintScan hit to PR00103, cAMP-dependent protein kinase signature
257309001277	FPrintScan hit to PR00103, cAMP-dependent protein kinase signature
257309001278	FPrintScan hit to PR00103, cAMP-dependent protein kinase signature
257309001279	FPrintScan hit to PR00103, cAMP-dependent protein kinase signature
257309001280	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
257309001281	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
257309001282	minor groove reading motif; other site
257309001283	helix-hairpin-helix signature motif; other site
257309001284	substrate binding pocket [chemical binding]; other site
257309001285	active site
257309001286	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
257309001287	HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair protein
257309001288	HMMSmart hit to SM00478, endonuclease III
257309001289	HMMSmart hit to SM00525, No definition
257309001290	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
257309001291	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
257309001292	catalytic residues [active]
257309001293	ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).
257309001294	ScanRegExp hit to PS00194, Thioredoxin family active site.
257309001295	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
257309001296	putative active site [active]
257309001297	putative CoA binding site [chemical binding]; other site
257309001298	nudix motif; other site
257309001299	metal binding site [ion binding]; metal-binding site
257309001300	HMMPfam hit to PF00293, MutT-like domain
257309001301	ScanRegExp hit to PS01293, Uncharacterized protein family UPF0035 signature.
257309001302	Colicin V production protein; Region: Colicin_V; pfam02674
257309001303	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
257309001304	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
257309001305	4 probable transmembrane helices predicted for DIP0307 by TMHMM2.0
257309001306	FPrintScan hit to PR00839, V8 serine protease signature
257309001307	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309001308	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309001309	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309001310	FPrintScan hit to PR00839, V8 serine protease signature
257309001311	FPrintScan hit to PR00839, V8 serine protease signature
257309001312	ScanRegExp hit to PS00294, Prenyl group binding site (CAAX box).
257309001313	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
257309001314	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
257309001315	HMMPfam hit to PF00561, alpha/beta hydrolase fold
257309001316	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature; FPrintScan hit to PR00412, Epoxide hydrolase signature
257309001317	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309001318	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature; FPrintScan hit to PR00412, Epoxide hydrolase signature
257309001319	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature; FPrintScan hit to PR00412, Epoxide hydrolase signature
257309001320	FPrintScan hit to PR00412, Epoxide hydrolase signature
257309001321	Protein of unknown function (DUF1469); Region: DUF1469; pfam07332
257309001322	2 probable transmembrane helices predicted for DIP0309 by TMHMM2.0
257309001323	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
257309001324	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309001325	motif II; other site
257309001326	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309001327	helicase/secretion neighborhood CpaE-like protein; Region: CpaE_hom_Actino; TIGR03815
257309001328	ScanRegExp hit to PS00687, Aldehyde dehydrogenases glutamic acid active site.
257309001329	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
257309001330	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
257309001331	ATP binding site [chemical binding]; other site
257309001332	Walker A motif; other site
257309001333	hexamer interface [polypeptide binding]; other site
257309001334	Walker B motif; other site
257309001335	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309001336	HMMPfam hit to PF00437, Bacterial type II secretion system protein
257309001337	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001338	ScanRegExp hit to PS00778, Histidine acid phosphatases active site signature.
257309001339	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
257309001340	4 probable transmembrane helices predicted for DIP0314 by TMHMM2.0
257309001341	ProfileScan hit to PS50310, Alanine-rich region.
257309001342	1 probable transmembrane helix predicted for DIP0315 by TMHMM2.0
257309001343	Protein of unknown function (DUF4244); Region: DUF4244; pfam14029
257309001344	1 probable transmembrane helix predicted for DIP0316 by TMHMM2.0
257309001345	helicase/secretion neighborhood TadE-like protein; Region: tadE_like_DECH; TIGR03816
257309001346	ProfileScan hit to PS50310, Alanine-rich region.
257309001347	helicase/secretion neighborhood putative DEAH-box helicase; Region: DECH_helic; TIGR03817
257309001348	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309001349	ATP binding site [chemical binding]; other site
257309001350	putative Mg++ binding site [ion binding]; other site
257309001351	nucleotide binding region [chemical binding]; other site
257309001352	helicase superfamily c-terminal domain; Region: HELICc; smart00490
257309001353	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
257309001354	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309001355	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309001356	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309001357	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309001358	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
257309001359	DNA-binding site [nucleotide binding]; DNA binding site
257309001360	RNA-binding motif; other site
257309001361	HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain
257309001362	HMMSmart hit to SM00357, Cold shock protein domain
257309001363	FPrintScan hit to PR00050, Cold shock protein signature
257309001364	BlastProDom hit to PD000621, PD000621
257309001365	ScanRegExp hit to PS00352, 'Cold-shock' domain signature.
257309001366	FPrintScan hit to PR00050, Cold shock protein signature
257309001367	FPrintScan hit to PR00050, Cold shock protein signature
257309001368	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
257309001369	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309001370	Walker A/P-loop; other site
257309001371	ATP binding site [chemical binding]; other site
257309001372	Q-loop/lid; other site
257309001373	ABC transporter signature motif; other site
257309001374	Walker B; other site
257309001375	D-loop; other site
257309001376	H-loop/switch region; other site
257309001377	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309001378	HMMPfam hit to PF00005, ABC transporter
257309001379	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309001380	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001381	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309001382	ScanRegExp hit to PS00211, ABC transporters family signature.
257309001383	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
257309001384	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309001385	Walker A/P-loop; other site
257309001386	ATP binding site [chemical binding]; other site
257309001387	Q-loop/lid; other site
257309001388	ABC transporter signature motif; other site
257309001389	Walker B; other site
257309001390	D-loop; other site
257309001391	H-loop/switch region; other site
257309001392	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309001393	HMMPfam hit to PF00005, ABC transporter
257309001394	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309001395	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001396	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309001397	ScanRegExp hit to PS00211, ABC transporters family signature.
257309001398	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309001399	Major Facilitator Superfamily; Region: MFS_1; pfam07690
257309001400	putative substrate translocation pore; other site
257309001401	10 probable transmembrane helices predicted for DIP0323 by TMHMM2.0
257309001402	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
257309001403	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490
257309001404	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309001405	ScanRegExp hit to PS01040, Bacterial extracellular solute-binding proteins, family 5 signature.
257309001406	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001407	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309001408	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
257309001409	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
257309001410	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
257309001411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309001412	dimer interface [polypeptide binding]; other site
257309001413	conserved gate region; other site
257309001414	putative PBP binding loops; other site
257309001415	ABC-ATPase subunit interface; other site
257309001416	12 probable transmembrane helices predicted for DIP0325 by TMHMM2.0
257309001417	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309001418	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
257309001419	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
257309001420	NAD(P) binding site [chemical binding]; other site
257309001421	active site
257309001422	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
257309001423	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
257309001424	DNA topoisomerase I, bacterial; Region: topA_bact; TIGR01051
257309001425	active site
257309001426	interdomain interaction site; other site
257309001427	putative metal-binding site [ion binding]; other site
257309001428	nucleotide binding site [chemical binding]; other site
257309001429	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
257309001430	domain I; other site
257309001431	DNA binding groove [nucleotide binding]
257309001432	phosphate binding site [ion binding]; other site
257309001433	domain II; other site
257309001434	domain III; other site
257309001435	nucleotide binding site [chemical binding]; other site
257309001436	catalytic site [active]
257309001437	domain IV; other site
257309001438	Uncharacterized C-terminal domain of topoisomerase IA [General function prediction only]; Region: COG1754
257309001439	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
257309001440	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
257309001441	HMMPfam hit to PF01751, Toprim domain
257309001442	HMMSmart hit to SM00493, No definition
257309001443	FPrintScan hit to PR00417, Prokaryotic DNA topoisomerase I signature
257309001444	HMMSmart hit to SM00436, Bacterial DNA topoisomeraes I ATP-binding domain
257309001445	HMMPfam hit to PF01131, DNA topoisomerase
257309001446	FPrintScan hit to PR00417, Prokaryotic DNA topoisomerase I signature
257309001447	HMMSmart hit to SM00437, Bacterial DNA topoisomerase I DNA-binding domain
257309001448	ScanRegExp hit to PS00396, Prokaryotic DNA topoisomerase I active site.
257309001449	FPrintScan hit to PR00417, Prokaryotic DNA topoisomerase I signature
257309001450	FPrintScan hit to PR00417, Prokaryotic DNA topoisomerase I signature
257309001451	FPrintScan hit to PR00417, Prokaryotic DNA topoisomerase I signature
257309001452	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
257309001453	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
257309001454	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
257309001455	active site
257309001456	HMMPfam hit to PF01569, PAP2 superfamily
257309001457	6 probable transmembrane helices predicted for DIP0328 by TMHMM2.0
257309001458	HMMSmart hit to SM00014, Acid phosphatase homologues
257309001459	ProfileScan hit to PS50226, PA-phosphatase and other phosphomonoesterases.
257309001460	Predicted membrane protein [Function unknown]; Region: COG1297
257309001461	putative oligopeptide transporter, OPT family; Region: TIGR00733
257309001462	18 probable transmembrane helices predicted for DIP0329 by TMHMM2.0
257309001463	Laminin G domain; Region: Laminin_G_2; pfam02210
257309001464	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
257309001465	catalytic site [active]
257309001466	Asp-box motif; other site
257309001467	HMMPfam hit to PF02012, BNR repeat
257309001468	HMMPfam hit to PF02012, BNR repeat
257309001469	HMMPfam hit to PF02012, BNR repeat
257309001470	HMMPfam hit to PF02012, BNR repeat
257309001471	HMMPfam hit to PF02012, BNR repeat
257309001472	ScanRegExp hit to PS00087, Copper/Zinc superoxide dismutase signature 1.
257309001473	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
257309001474	dimerization interface [polypeptide binding]; other site
257309001475	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
257309001476	cyclase homology domain; Region: CHD; cd07302
257309001477	nucleotidyl binding site; other site
257309001478	metal binding site [ion binding]; metal-binding site
257309001479	dimer interface [polypeptide binding]; other site
257309001480	HMMSmart hit to SM00044, Adenylyl- / guanylyl cyclase, catalytic domain
257309001481	ProfileScan hit to PS50125, Guanylate cyclases profile.
257309001482	HMMPfam hit to PF00211, Adenylate and Guanylate cyclase catalytic domain
257309001483	HMMSmart hit to SM00304, HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
257309001484	HMMPfam hit to PF00672, HAMP domain
257309001485	6 probable transmembrane helices predicted for DIP0332 by TMHMM2.0
257309001486	DNA polymerase III subunit delta'; Validated; Region: PRK07940
257309001487	DNA polymerase III subunit delta'; Validated; Region: PRK08485
257309001488	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
257309001489	Anomalous G+C content (51.29%).  pathogenicity island. Not present in C.glutamicum. Contains a CDS possibly encoding for a starch degrading enzyme: This ability of degrading starch is a characteristic of the Corynebacterium diphtheria strain gravis and not of strain mitis nor strain intermedius
257309001490	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
257309001491	1 probable transmembrane helix predicted for DIP0335 by TMHMM2.0
257309001492	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
257309001493	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
257309001494	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
257309001495	DNA binding site [nucleotide binding]
257309001496	Pseudogene. Similar to Salmonella typhimurium LT2 cytoplasmic protein RhuM TR:AAL22613 (EMBL:AE008874) (345 aa) fasta scores: E(): 3.5e-25, 46.87% id in 224 aa. Presents frameshifts at residues 86 and 180; phage protein (pseudogene)
257309001497	1 probable transmembrane helix predicted for DIP0345 by TMHMM2.0
257309001498	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
257309001499	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
257309001500	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
257309001501	Fic family protein [Function unknown]; Region: COG3177
257309001502	Fic/DOC family; Region: Fic; pfam02661
257309001503	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
257309001504	Trypsin; Region: Trypsin; pfam00089
257309001505	active site
257309001506	ProfileScan hit to PS50240, Serine proteases, trypsin domain profile.
257309001507	HMMSmart hit to SM00020, Trypsin-like serine protease
257309001508	HMMPfam hit to PF00089, Trypsin
257309001509	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309001510	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001511	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309001512	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309001513	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
257309001514	putative DNA binding site [nucleotide binding]; other site
257309001515	putative Zn2+ binding site [ion binding]; other site
257309001516	Predicted helix-turn-helix motif with score 1076 (+2.85 SD) at aa 75-96, sequence PTARQIAGEIGITKRMVNIHLK
257309001517	Pseudogene. Similar to Streptomyces coelicolor insertion element IS110 hypothetical 43.6 kDa protein SC3C8.10 and SCC57A.30c and SCG2.18 and SC5E9.30 SW:YIS1_STRCO (P19780) (405 aa) fasta scores: E(): 7.8e-21, 37.09% id in 337 aa. Presents frameshifts at residues 211 and 249; IS element tranposase (pseudogene)
257309001518	HMMPfam hit to PF01548, Transposase
257309001519	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
257309001520	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
257309001521	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
257309001522	active site
257309001523	catalytic site [active]
257309001524	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
257309001525	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
257309001526	alpha-1,6-glucosidases, pullulanase-type; Region: pullul_strch; TIGR02103
257309001527	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
257309001528	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
257309001529	Ca binding site [ion binding]; other site
257309001530	active site
257309001531	catalytic site [active]
257309001532	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
257309001533	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309001534	HMMPfam hit to PF02922, Isoamylase N-terminal domain
257309001535	1 probable transmembrane helix predicted for DIP0357 by TMHMM2.0
257309001536	acyl-CoA synthetase; Validated; Region: PRK07788
257309001537	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001538	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001539	acyl-activating enzyme (AAE) consensus motif; other site
257309001540	acyl-activating enzyme (AAE) consensus motif; other site
257309001541	AMP binding site [chemical binding]; other site
257309001542	active site
257309001543	CoA binding site [chemical binding]; other site
257309001544	HMMPfam hit to PF00501, AMP-binding enzyme
257309001545	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309001546	SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is...; Region: SEST_like; cd01823
257309001547	active site
257309001548	catalytic triad [active]
257309001549	oxyanion hole [active]
257309001550	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
257309001551	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
257309001552	substrate binding site; other site
257309001553	tetramer interface; other site
257309001554	HMMPfam hit to PF00483, Nucleotidyl transferase
257309001555	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
257309001556	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
257309001557	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
257309001558	NADP binding site [chemical binding]; other site
257309001559	active site
257309001560	putative substrate binding site [chemical binding]; other site
257309001561	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase
257309001562	BlastProDom hit to PD001462, PD001462
257309001563	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
257309001564	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
257309001565	NAD binding site [chemical binding]; other site
257309001566	substrate binding site [chemical binding]; other site
257309001567	homodimer interface [polypeptide binding]; other site
257309001568	active site
257309001569	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase
257309001570	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
257309001571	Zn binding site [ion binding]; other site
257309001572	HMMPfam hit to PF01433, Peptidase M1
257309001573	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309001574	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309001575	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309001576	HMMPfam hit to PF01433, Peptidase M1
257309001577	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309001578	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309001579	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
257309001580	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
257309001581	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309001582	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309001583	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309001584	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309001585	HMMPfam hit to PF00326, Prolyl oligopeptidase
257309001586	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309001587	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309001588	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309001589	HMMPfam hit to PF02897, Prolyl oligopeptidase, N-terminal beta-propeller domain
257309001590	Putative esterase; Region: Esterase; pfam00756
257309001591	HMMPfam hit to PF00756,  esterase
257309001592	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK07818
257309001593	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
257309001594	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
257309001595	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
257309001596	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase
257309001597	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001598	ProfileScan hit to PS50205, NAD binding site.
257309001599	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309001600	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001601	ScanRegExp hit to PS00076, Pyridine nucleotide-disulphide oxidoreductases class-I active site.
257309001602	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309001603	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001604	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309001605	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001606	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309001607	ProfileScan hit to PS50205, NAD binding site.
257309001608	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001609	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309001610	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001611	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001612	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
257309001613	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001614	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309001615	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001616	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
257309001617	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309001618	non-specific DNA binding site [nucleotide binding]; other site
257309001619	salt bridge; other site
257309001620	sequence-specific DNA binding site [nucleotide binding]; other site
257309001621	Predicted transcriptional regulator [General function prediction only]; Region: COG3800
257309001622	Domain of unknown function (DUF955); Region: DUF955; pfam06114
257309001623	Predicted transcriptional regulator (DUF2083); Region: DUF2083; pfam09856
257309001624	ScanRegExp hit to PS00622, Bacterial regulatory proteins, luxR family signature.
257309001625	HMMSmart hit to SM00530, Helix-turn-helix XRE-family like proteins, DNA-binding
257309001626	HMMPfam hit to PF01381, Helix-turn-helix
257309001627	Predicted helix-turn-helix motif with score 2003 (+6.01 SD) at aa 19-40, sequence LTQAALAELLGISASYINQIEH
257309001628	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
257309001629	putative Iron-sulfur protein interface [polypeptide binding]; other site
257309001630	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
257309001631	proximal heme binding site [chemical binding]; other site
257309001632	distal heme binding site [chemical binding]; other site
257309001633	putative dimer interface [polypeptide binding]; other site
257309001634	5 probable transmembrane helices predicted for DIP0370 by TMHMM2.0
257309001635	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
257309001636	L-aspartate oxidase; Provisional; Region: PRK06175
257309001637	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
257309001638	HMMPfam hit to PF00890, FAD binding domain
257309001639	HMMPfam hit to PF00890, FAD binding domain
257309001640	HMMPfam hit to PF02910, Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain
257309001641	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
257309001642	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
257309001643	ScanRegExp hit to PS00197, 2Fe-2S ferredoxins, iron-sulfur binding region signature.
257309001644	HMMPfam hit to PF00037, 4Fe-4S binding domain
257309001645	ScanRegExp hit to PS00198, 4Fe-4S ferredoxins, iron-sulfur binding region signature.
257309001646	HMMPfam hit to PF00037, 4Fe-4S binding domain
257309001647	2 probable transmembrane helices predicted for DIP0373 by TMHMM2.0
257309001648	1 probable transmembrane helix predicted for DIP0374 by TMHMM2.0
257309001649	Predicted membrane protein [Function unknown]; Region: COG2733
257309001650	3 probable transmembrane helices predicted for DIP0375 by TMHMM2.0
257309001651	Protein of unknown function (DUF2516); Region: DUF2516; pfam10724
257309001652	2 probable transmembrane helices predicted for DIP0376 by TMHMM2.0
257309001653	Class I aldolases; Region: Aldolase_Class_I; cd00945
257309001654	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
257309001655	1 probable transmembrane helix predicted for DIP0378 by TMHMM2.0
257309001656	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
257309001657	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309001658	FeS/SAM binding site; other site
257309001659	BlastProDom hit to PD004758, PD004758
257309001660	ScanRegExp hit to PS01087, Radical activating enzymes signature.
257309001661	ScanRegExp hit to PS00190, Cytochrome c family heme-binding site signature.
257309001662	HMMPfam hit to PF02143, Radical activating enzyme
257309001663	Pseudogene. Similar to Escherichia coli formate acetyltransferase 1 PflB or Pfl or B0903 SW:PFLB_ECOLI (P09373) (759 aa) fasta scores: E(): 1.5e-171, 57.65% id in 758 aa. Presents a frameshift at residue 698;formate acetyltransferase 1 (pseudogene)
257309001664	ScanRegExp hit to PS00850, Glycine radical signature.
257309001665	ScanRegExp hit to PS00136, Serine proteases, subtilase, aspartic acid active site.
257309001666	HMMPfam hit to PF02901, Pyruvate formate lyase
257309001667	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
257309001668	Protein of unknown function (DUF2505); Region: DUF2505; pfam10698
257309001669	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13903
257309001670	FAD binding domain; Region: FAD_binding_4; pfam01565
257309001671	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
257309001672	HMMPfam hit to PF02215, UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding domain
257309001673	HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
257309001674	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
257309001675	pentamer interface [polypeptide binding]; other site
257309001676	dodecaamer interface [polypeptide binding]; other site
257309001677	ScanRegExp hit to PS00294, Prenyl group binding site (CAAX box).
257309001678	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK05605
257309001679	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001680	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001681	acyl-activating enzyme (AAE) consensus motif; other site
257309001682	AMP binding site [chemical binding]; other site
257309001683	active site
257309001684	CoA binding site [chemical binding]; other site
257309001685	HMMPfam hit to PF00501, AMP-binding enzyme
257309001686	FPrintScan hit to PR00154, AMP-binding signature
257309001687	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309001688	FPrintScan hit to PR00154, AMP-binding signature
257309001689	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK05605
257309001690	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001691	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001692	acyl-activating enzyme (AAE) consensus motif; other site
257309001693	AMP binding site [chemical binding]; other site
257309001694	active site
257309001695	CoA binding site [chemical binding]; other site
257309001696	HMMPfam hit to PF00501, AMP-binding enzyme
257309001697	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309001698	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
257309001699	D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449
257309001700	putative ADP-binding pocket [chemical binding]; other site
257309001701	HMMPfam hit to PF00534, Glycosyl transferases group 1
257309001702	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309001703	catalytic core [active]
257309001704	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309001705	HMMPfam hit to PF00300, Phosphoglycerate mutase
257309001706	ScanRegExp hit to PS00175, Phosphoglycerate mutase phosphohistidine signature.
257309001707	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
257309001708	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
257309001709	dimer interface [polypeptide binding]; other site
257309001710	phosphorylation site [posttranslational modification]
257309001711	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309001712	ATP binding site [chemical binding]; other site
257309001713	Mg2+ binding site [ion binding]; other site
257309001714	G-X-G motif; other site
257309001715	1 probable transmembrane helix predicted for DIP0390 by TMHMM2.0
257309001716	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain; HMMSmart hit to SM00388, His Kinase A (phosphoacceptor) domain
257309001717	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309001718	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309001719	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001720	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001721	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001722	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309001723	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
257309001724	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309001725	active site
257309001726	phosphorylation site [posttranslational modification]
257309001727	intermolecular recognition site; other site
257309001728	dimerization interface [polypeptide binding]; other site
257309001729	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
257309001730	DNA binding site [nucleotide binding]
257309001731	HMMPfam hit to PF00072, Response regulator receiver domain
257309001732	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309001733	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309001734	HMMPfam hit to PF00486, Transcriptional regulatory protein, C terminal
257309001735	3 probable transmembrane helices predicted for DIP0393 by TMHMM2.0
257309001736	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
257309001737	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
257309001738	HMMPfam hit to PF01089, Delta 1-pyrroline-5-carboxylate reductase
257309001739	ScanRegExp hit to PS00521, Delta 1-pyrroline-5-carboxylate reductase signature.
257309001740	DNA binding domain, excisionase family; Region: excise; TIGR01764
257309001741	Predicted helix-turn-helix motif with score 1715 (+5.03 SD) at aa 10-31, sequence LTVAEVAEIMRVSKMTVYRLVH
257309001742	Thioredoxin; Region: Thioredoxin_4; cl17273
257309001743	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
257309001744	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
257309001745	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
257309001746	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309001747	motif II; other site
257309001748	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309001749	Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768
257309001750	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
257309001751	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
257309001752	tRNA; other site
257309001753	putative tRNA binding site [nucleotide binding]; other site
257309001754	putative NADP binding site [chemical binding]; other site
257309001755	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
257309001756	HMMPfam hit to PF00745, Glutamyl-tRNAGlu reductase
257309001757	ScanRegExp hit to PS00747, Glutamyl-tRNA reductase signature.
257309001758	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
257309001759	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
257309001760	domain interfaces; other site
257309001761	active site
257309001762	HMMPfam hit to PF01379, Porphobilinogen deaminase
257309001763	FPrintScan hit to PR00151, Porphobilinogen deaminase signature
257309001764	FPrintScan hit to PR00151, Porphobilinogen deaminase signature
257309001765	FPrintScan hit to PR00151, Porphobilinogen deaminase signature
257309001766	ScanRegExp hit to PS00453, FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
257309001767	FPrintScan hit to PR00151, Porphobilinogen deaminase signature
257309001768	ScanRegExp hit to PS00533, Porphobilinogen deaminase cofactor-binding site.
257309001769	S-AdoMet dependent tetrapyrrole methylases; Region: TP_methylase; cd09815
257309001770	active site
257309001771	homodimer interface [polypeptide binding]; other site
257309001772	SAM binding site [chemical binding]; other site
257309001773	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
257309001774	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
257309001775	active site
257309001776	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309001777	ScanRegExp hit to PS00839, Uroporphyrin-III C-methyltransferase signature 1.
257309001778	HMMPfam hit to PF02602, Uroporphyrinogen-III synthase HemD
257309001779	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
257309001780	dimer interface [polypeptide binding]; other site
257309001781	active site
257309001782	Schiff base residues; other site
257309001783	HMMPfam hit to PF00490, Delta-aminolevulinic acid dehydratase
257309001784	BlastProDom hit to PD002304, PD002304
257309001785	FPrintScan hit to PR00144, Delta-aminolevulinic acid dehydratase signature
257309001786	FPrintScan hit to PR00144, Delta-aminolevulinic acid dehydratase signature
257309001787	FPrintScan hit to PR00144, Delta-aminolevulinic acid dehydratase signature
257309001788	FPrintScan hit to PR00144, Delta-aminolevulinic acid dehydratase signature
257309001789	ScanRegExp hit to PS00169, Delta-aminolevulinic acid dehydratase active site.
257309001790	FPrintScan hit to PR00144, Delta-aminolevulinic acid dehydratase signature
257309001791	FPrintScan hit to PR00144, Delta-aminolevulinic acid dehydratase signature
257309001792	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
257309001793	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
257309001794	ProfileScan hit to PS50323, Arginine-rich region.
257309001795	7 probable transmembrane helices predicted for DIP0405 by TMHMM2.0
257309001796	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309001797	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309001798	HMMPfam hit to PF00122, E1-E2 ATPase
257309001799	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309001800	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309001801	Predicted membrane protein [Function unknown]; Region: COG2311
257309001802	Protein of unknown function (DUF418); Region: DUF418; pfam04235
257309001803	10 probable transmembrane helices predicted for DIP0406 by TMHMM2.0
257309001804	ScanRegExp hit to PS00622, Bacterial regulatory proteins, luxR family signature.
257309001805	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
257309001806	substrate binding site [chemical binding]; other site
257309001807	active site
257309001808	HMMPfam hit to PF01208, Uroporphyrinogen decarboxylase (URO-D)
257309001809	ScanRegExp hit to PS00906, Uroporphyrinogen decarboxylase signature 1.
257309001810	ScanRegExp hit to PS00907, Uroporphyrinogen decarboxylase signature 2.
257309001811	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
257309001812	HMMPfam hit to PF01593, Flavin containing amine oxidase
257309001813	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
257309001814	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
257309001815	inhibitor-cofactor binding pocket; inhibition site
257309001816	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309001817	catalytic residue [active]
257309001818	HMMPfam hit to PF00202, Aminotransferase class-III
257309001819	ScanRegExp hit to PS00600, Aminotransferases class-III pyridoxal-phosphate attachment site.
257309001820	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309001821	catalytic core [active]
257309001822	HMMPfam hit to PF00300, Phosphoglycerate mutase
257309001823	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
257309001824	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
257309001825	catalytic residues [active]
257309001826	ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).
257309001827	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
257309001828	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
257309001829	6 probable transmembrane helices predicted for DIP0412 by TMHMM2.0
257309001830	HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembrane region
257309001831	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; COG1333
257309001832	ResB-like family; Region: ResB; pfam05140
257309001833	4 probable transmembrane helices predicted for DIP0413 by TMHMM2.0
257309001834	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
257309001835	8 probable transmembrane helices predicted for DIP0414 by TMHMM2.0
257309001836	HMMPfam hit to PF01578, Cytochrome C assembly protein
257309001837	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
257309001838	dimerization interface [polypeptide binding]; other site
257309001839	putative DNA binding site [nucleotide binding]; other site
257309001840	putative Zn2+ binding site [ion binding]; other site
257309001841	HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family
257309001842	HMMSmart hit to SM00418, helix_turn_helix, Arsenical Resistance Operon Repressor, DNA-binding
257309001843	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309001844	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309001845	Predicted helix-turn-helix motif with score 1021 (+2.66 SD) at aa 32-53, sequence LCCVDLSEALAVSAPTVTHHMK
257309001846	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309001847	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309001848	1 probable transmembrane helix predicted for DIP0416 by TMHMM2.0
257309001849	Protein of unknown function (DUF4229); Region: DUF4229; pfam14012
257309001850	2 probable transmembrane helices predicted for DIP0417 by TMHMM2.0
257309001851	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
257309001852	UbiA prenyltransferase family; Region: UbiA; pfam01040
257309001853	7 probable transmembrane helices predicted for DIP0418 by TMHMM2.0
257309001854	HMMPfam hit to PF01040, UbiA prenyltransferase
257309001855	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
257309001856	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309001857	active site
257309001858	HMMSmart hit to SM00507, HNH nucleases
257309001859	HMMPfam hit to PF01844, HNH endonuclease
257309001860	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309001861	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK07824
257309001862	acyl-activating enzyme (AAE) consensus motif; other site
257309001863	AMP binding site [chemical binding]; other site
257309001864	active site
257309001865	CoA binding site [chemical binding]; other site
257309001866	HMMPfam hit to PF00501, AMP-binding enzyme
257309001867	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309001868	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
257309001869	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
257309001870	substrate binding site [chemical binding]; other site
257309001871	oxyanion hole (OAH) forming residues; other site
257309001872	trimer interface [polypeptide binding]; other site
257309001873	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309001874	HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase
257309001875	ScanRegExp hit to PS00166, Enoyl-CoA hydratase/isomerase signature.
257309001876	O-succinylbenzoate synthase; Provisional; Region: PRK02901
257309001877	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
257309001878	active site
257309001879	HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
257309001880	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
257309001881	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
257309001882	dimer interface [polypeptide binding]; other site
257309001883	tetramer interface [polypeptide binding]; other site
257309001884	PYR/PP interface [polypeptide binding]; other site
257309001885	TPP binding site [chemical binding]; other site
257309001886	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
257309001887	TPP-binding site; other site
257309001888	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
257309001889	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
257309001890	2 probable transmembrane helices predicted for DIP0424 by TMHMM2.0
257309001891	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
257309001892	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
257309001893	HMMPfam hit to PF00534, Glycosyl transferases group 1
257309001894	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
257309001895	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309001896	S-adenosylmethionine binding site [chemical binding]; other site
257309001897	HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase
257309001898	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309001899	ProfileScan hit to PS50124, Generic methyl-transferase profile.
257309001900	A subgroup of L-lactate dehydrogenases; Region: LDH_3; cd05290
257309001901	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
257309001902	NAD binding site [chemical binding]; other site
257309001903	dimer interface [polypeptide binding]; other site
257309001904	tetramer (dimer of dimers) interface [polypeptide binding]; other site
257309001905	substrate binding site [chemical binding]; other site
257309001906	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-terminal domain
257309001907	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309001908	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309001909	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding domain
257309001910	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309001911	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309001912	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309001913	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
257309001914	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309001915	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309001916	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309001917	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001918	HMMPfam hit to PF01494, FAD binding domain
257309001919	ProfileScan hit to PS50205, NAD binding site.
257309001920	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309001921	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
257309001922	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
257309001923	substrate binding pocket [chemical binding]; other site
257309001924	chain length determination region; other site
257309001925	substrate-Mg2+ binding site; other site
257309001926	catalytic residues [active]
257309001927	aspartate-rich region 1; other site
257309001928	active site lid residues [active]
257309001929	aspartate-rich region 2; other site
257309001930	HMMPfam hit to PF00348, Polyprenyl synthetase
257309001931	ScanRegExp hit to PS00038, Myc-type, 'helix-loop-helix' dimerization domain signature.
257309001932	ScanRegExp hit to PS00444, Polyprenyl synthetases signature 2.
257309001933	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
257309001934	HMMPfam hit to PF00584, SecE/Sec61-gamma subunits of protein translocation complex
257309001935	1 probable transmembrane helix predicted for DIP0430 by TMHMM2.0
257309001936	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
257309001937	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
257309001938	putative homodimer interface [polypeptide binding]; other site
257309001939	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
257309001940	heterodimer interface [polypeptide binding]; other site
257309001941	homodimer interface [polypeptide binding]; other site
257309001942	HMMPfam hit to PF02357, Transcription termination factor nusG
257309001943	FPrintScan hit to PR00338, Transcription termination factor NUSG signature
257309001944	FPrintScan hit to PR00338, Transcription termination factor NUSG signature
257309001945	FPrintScan hit to PR00338, Transcription termination factor NUSG signature
257309001946	ScanRegExp hit to PS01014, Transcription termination factor nusG signature.
257309001947	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
257309001948	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
257309001949	23S rRNA interface [nucleotide binding]; other site
257309001950	L7/L12 interface [polypeptide binding]; other site
257309001951	putative thiostrepton binding site; other site
257309001952	L25 interface [polypeptide binding]; other site
257309001953	BlastProDom hit to PD001367, PD001367; HMMPfam hit to PF00298, Ribosomal protein L11
257309001954	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
257309001955	mRNA/rRNA interface [nucleotide binding]; other site
257309001956	HMMPfam hit to PF00687, Ribosomal protein L1p/L10e family
257309001957	BlastProDom hit to PD001314, PD001314
257309001958	ScanRegExp hit to PS01199, Ribosomal protein L1 signature.
257309001959	putative transposase OrfB; Reviewed; Region: PHA02517
257309001960	HTH-like domain; Region: HTH_21; pfam13276
257309001961	Integrase core domain; Region: rve; pfam00665
257309001962	Integrase core domain; Region: rve_2; pfam13333
257309001963	HMMPfam hit to PF00665, Integrase core domain
257309001964	Homeodomain-like domain; Region: HTH_23; cl17451
257309001965	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
257309001966	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309001967	Predicted helix-turn-helix motif with score 1129 (+3.03 SD) at aa 23-44, sequence YGSRAVANRLGVRREQVRHLED
257309001968	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
257309001969	23S rRNA interface [nucleotide binding]; other site
257309001970	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
257309001971	HMMPfam hit to PF00466, Ribosomal protein L10
257309001972	ScanRegExp hit to PS01109, Ribosomal protein L10 signature.
257309001973	50S ribosomal protein L7/L12; Reviewed; Region: rplL; PRK00157
257309001974	L11 interface [polypeptide binding]; other site
257309001975	putative EF-Tu interaction site [polypeptide binding]; other site
257309001976	putative EF-G interaction site [polypeptide binding]; other site
257309001977	HMMPfam hit to PF00542, Ribosomal protein L7/L12 C-terminal domain
257309001978	BlastProDom hit to PD001326, PD001326
257309001979	Anomalous G+C content (52.22%).  fimbriae-related pathogenicity islet
257309001980	anchored repeat ABC transporter, substrate-binding protein; Region: anch_rpt_subst; TIGR03772
257309001981	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309001982	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309001983	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309001984	HMMPfam hit to PF01297, Periplasmic solute binding protein family
257309001985	FPrintScan hit to PR00691, Adhesin B signature
257309001986	FPrintScan hit to PR00690, Adhesin family signature
257309001987	FPrintScan hit to PR00691, Adhesin B signature
257309001988	FPrintScan hit to PR00690, Adhesin family signature
257309001989	FPrintScan hit to PR00691, Adhesin B signature
257309001990	FPrintScan hit to PR00690, Adhesin family signature
257309001991	FPrintScan hit to PR00691, Adhesin B signature
257309001992	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309001993	1 probable transmembrane helix predicted for DIP0439 by TMHMM2.0
257309001994	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
257309001995	anchored repeat-type ABC transporter, ATP-binding subunit; Region: anch_rpt_ABC; TIGR03771
257309001996	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309001997	HMMPfam hit to PF00005, ABC transporter
257309001998	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309001999	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002000	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002001	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002002	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
257309002003	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309002004	ABC-ATPase subunit  interface; other site
257309002005	dimer interface [polypeptide binding]; other site
257309002006	putative PBP binding regions; other site
257309002007	9 probable transmembrane helices predicted for DIP0441 by TMHMM2.0
257309002008	HMMPfam hit to PF00950, ABC 3 transport family
257309002009	putative ABC transporter-associated repeat protein; Region: anch_rpt_wall; TIGR03773
257309002010	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309002011	1 probable transmembrane helix predicted for DIP0442 by TMHMM2.0
257309002012	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309002013	ScanRegExp hit to PS00225, Crystallins beta and gamma 'Greek key' motif signature.
257309002014	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002015	potential sortase anchor site LPDTG
257309002016	1 probable transmembrane helix predicted for DIP0443 by TMHMM2.0
257309002017	ProfileScan hit to PS50318, Lysine-rich region.
257309002018	1 probable transmembrane helix predicted for DIP0444 by TMHMM2.0
257309002019	Protein of unknown function (DUF3068); Region: DUF3068; pfam11271
257309002020	1 probable transmembrane helix predicted for DIP0445 by TMHMM2.0
257309002021	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
257309002022	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
257309002023	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
257309002024	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
257309002025	RPB1 interaction site [polypeptide binding]; other site
257309002026	RPB10 interaction site [polypeptide binding]; other site
257309002027	RPB11 interaction site [polypeptide binding]; other site
257309002028	RPB3 interaction site [polypeptide binding]; other site
257309002029	RPB12 interaction site [polypeptide binding]; other site
257309002030	HMMPfam hit to PF00562, RNA polymerase beta subunit
257309002031	ScanRegExp hit to PS01166, RNA polymerases beta chain signature.
257309002032	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
257309002033	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
257309002034	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
257309002035	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
257309002036	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
257309002037	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
257309002038	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
257309002039	G-loop; other site
257309002040	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
257309002041	DNA binding site [nucleotide binding]
257309002042	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
257309002043	HMMPfam hit to PF00623, RNA polymerase alpha subunit
257309002044	HMMPfam hit to PF01854, RNA polymerase A/beta'/A'' subunit
257309002045	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309002046	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
257309002047	Walker A/P-loop; other site
257309002048	ATP binding site [chemical binding]; other site
257309002049	Q-loop/lid; other site
257309002050	ABC transporter signature motif; other site
257309002051	Walker B; other site
257309002052	D-loop; other site
257309002053	H-loop/switch region; other site
257309002054	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002055	HMMPfam hit to PF00005, ABC transporter
257309002056	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002057	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002058	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002059	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002060	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309002061	10 probable transmembrane helices predicted for DIP0449 by TMHMM2.0
257309002062	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309002063	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309002064	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309002065	Predicted helix-turn-helix motif with score 1309 (+3.65 SD) at aa 30-51, sequence EACKIVAPKLGVSWHTARQWTQ
257309002066	Pseudogene. Similar to Mycobacterium tuberculosis CDC1551 helicase, /conserved hypothetical protein MT2082 TR:AAK46361 (EMBL:AE007059) (1606 aa) fasta scores: E(): 2.1e-149, 57.16% id in 1662 aa. Contains a frameshift after residue 190; helicase (pseudogene)
257309002067	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309002068	FPrintScan hit to PR00142, RecA protein signature
257309002069	FPrintScan hit to PR00142, RecA protein signature
257309002070	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309002071	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309002072	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309002073	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309002074	FPrintScan hit to PR00142, RecA protein signature
257309002075	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
257309002076	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
257309002077	Histidine kinase; Region: HisKA_3; pfam07730
257309002078	5 probable transmembrane helices predicted for DIP0458 by TMHMM2.0
257309002079	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
257309002080	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309002081	active site
257309002082	phosphorylation site [posttranslational modification]
257309002083	intermolecular recognition site; other site
257309002084	dimerization interface [polypeptide binding]; other site
257309002085	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
257309002086	DNA binding residues [nucleotide binding]
257309002087	dimerization interface [polypeptide binding]; other site
257309002088	HMMPfam hit to PF00072, Response regulator receiver domain
257309002089	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309002090	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309002091	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family
257309002092	HMMSmart hit to SM00421, helix_turn_helix, Lux Regulon
257309002093	ProfileScan hit to PS50043, Helix-turn-helix domain, luxR and related types (substantial overlap with lysR type).
257309002094	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309002095	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309002096	Predicted helix-turn-helix motif with score 1227 (+3.37 SD) at aa 177-198, sequence KSNTEIAEELFISLPTVKTHVS
257309002097	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309002098	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309002099	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
257309002100	Walker A/P-loop; other site
257309002101	ATP binding site [chemical binding]; other site
257309002102	Q-loop/lid; other site
257309002103	ABC transporter signature motif; other site
257309002104	Walker B; other site
257309002105	D-loop; other site
257309002106	H-loop/switch region; other site
257309002107	Putative NAD(P)-binding; Region: NAD_binding_7; cl17660
257309002108	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002109	HMMPfam hit to PF00005, ABC transporter
257309002110	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002111	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002112	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002113	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002114	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
257309002115	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
257309002116	6 probable transmembrane helices predicted for DIP0461 by TMHMM2.0
257309002117	TIGR03943 family protein; Region: TIGR03943
257309002118	3 probable transmembrane helices predicted for DIP0462 by TMHMM2.0
257309002119	Predicted permeases [General function prediction only]; Region: COG0701
257309002120	8 probable transmembrane helices predicted for DIP0463 by TMHMM2.0
257309002121	Radical SAM superfamily; Region: Radical_SAM; pfam04055
257309002122	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309002123	FeS/SAM binding site; other site
257309002124	ScanRegExp hit to PS00190, Cytochrome c family heme-binding site signature.
257309002125	Anaerobic ribonucleoside-triphosphate reductase; Region: NRDD; pfam13597
257309002126	Class III ribonucleotide reductase; Region: RNR_III; cd01675
257309002127	effector binding site; other site
257309002128	active site
257309002129	Zn binding site [ion binding]; other site
257309002130	glycine loop; other site
257309002131	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
257309002132	S17 interaction site [polypeptide binding]; other site
257309002133	S8 interaction site; other site
257309002134	16S rRNA interaction site [nucleotide binding]; other site
257309002135	streptomycin interaction site [chemical binding]; other site
257309002136	23S rRNA interaction site [nucleotide binding]; other site
257309002137	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
257309002138	HMMPfam hit to PF00164, Ribosomal protein S12
257309002139	BlastProDom hit to PD000576, PD000576
257309002140	FPrintScan hit to PR01034, Ribosomal protein S12 signature
257309002141	FPrintScan hit to PR01034, Ribosomal protein S12 signature
257309002142	ScanRegExp hit to PS00055, Ribosomal protein S12 signature.
257309002143	FPrintScan hit to PR01034, Ribosomal protein S12 signature
257309002144	FPrintScan hit to PR01034, Ribosomal protein S12 signature
257309002145	FPrintScan hit to PR01034, Ribosomal protein S12 signature
257309002146	FPrintScan hit to PR01034, Ribosomal protein S12 signature
257309002147	30S ribosomal protein S7; Validated; Region: PRK05302
257309002148	HMMPfam hit to PF00177, Ribosomal protein S7p/S5e
257309002149	BlastProDom hit to PD000817, PD000817
257309002150	ScanRegExp hit to PS00052, Ribosomal protein S7 signature.
257309002151	elongation factor G; Reviewed; Region: PRK00007
257309002152	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
257309002153	G1 box; other site
257309002154	putative GEF interaction site [polypeptide binding]; other site
257309002155	GTP/Mg2+ binding site [chemical binding]; other site
257309002156	Switch I region; other site
257309002157	G2 box; other site
257309002158	G3 box; other site
257309002159	Switch II region; other site
257309002160	G4 box; other site
257309002161	G5 box; other site
257309002162	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
257309002163	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
257309002164	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
257309002165	HMMPfam hit to PF00009, Elongation factor Tu family
257309002166	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002167	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002168	ScanRegExp hit to PS00301, GTP-binding elongation factors signature.
257309002169	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002170	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002171	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002172	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002173	HMMPfam hit to PF03144
257309002174	HMMPfam hit to PF00679, Elongation factor G C-terminus
257309002175	elongation factor Tu; Reviewed; Region: PRK00049
257309002176	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
257309002177	G1 box; other site
257309002178	GEF interaction site [polypeptide binding]; other site
257309002179	GTP/Mg2+ binding site [chemical binding]; other site
257309002180	Switch I region; other site
257309002181	G2 box; other site
257309002182	G3 box; other site
257309002183	Switch II region; other site
257309002184	G4 box; other site
257309002185	G5 box; other site
257309002186	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
257309002187	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
257309002188	Antibiotic Binding Site [chemical binding]; other site
257309002189	HMMPfam hit to PF00009, Elongation factor Tu family
257309002190	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002191	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002192	ScanRegExp hit to PS00301, GTP-binding elongation factors signature.
257309002193	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002194	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002195	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002196	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309002197	HMMPfam hit to PF03144
257309002198	HMMPfam hit to PF03143
257309002199	Predicted membrane protein [Function unknown]; Region: COG2323
257309002200	3 probable transmembrane helices predicted for DIP0471 by TMHMM2.0
257309002201	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
257309002202	BlastProDom hit to PD001272, PD001272
257309002203	HMMPfam hit to PF00338, Ribosomal protein S10p/S20e
257309002204	FPrintScan hit to PR00971, Ribosomal protein S10 family signature
257309002205	ScanRegExp hit to PS00361, Ribosomal protein S10 signature.
257309002206	FPrintScan hit to PR00971, Ribosomal protein S10 family signature
257309002207	FPrintScan hit to PR00971, Ribosomal protein S10 family signature
257309002208	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
257309002209	BlastProDom hit to PD001374, PD001374
257309002210	HMMPfam hit to PF00297, Ribosomal protein L3
257309002211	ScanRegExp hit to PS00474, Ribosomal protein L3 signature.
257309002212	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
257309002213	HMMPfam hit to PF00573, Ribosomal protein L4/L1 family
257309002214	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
257309002215	HMMPfam hit to PF00276, Ribosomal protein L23
257309002216	BlastProDom hit to PD001141, PD001141
257309002217	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
257309002218	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
257309002219	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
257309002220	HMMPfam hit to PF00181, Ribosomal Proteins L2
257309002221	ScanRegExp hit to PS00467, Ribosomal protein L2 signature.
257309002222	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
257309002223	BlastProDom hit to PD001012, PD001012; HMMPfam hit to PF00203, Ribosomal protein S19
257309002224	FPrintScan hit to PR00975, Ribosomal protein S19 family signature
257309002225	ScanRegExp hit to PS00323, Ribosomal protein S19 signature.
257309002226	FPrintScan hit to PR00975, Ribosomal protein S19 family signature
257309002227	FPrintScan hit to PR00975, Ribosomal protein S19 family signature
257309002228	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
257309002229	putative translocon binding site; other site
257309002230	protein-rRNA interface [nucleotide binding]; other site
257309002231	HMMPfam hit to PF00237, Ribosomal protein L22p/L17e
257309002232	BlastProDom hit to PD001032, PD001032
257309002233	ScanRegExp hit to PS00464, Ribosomal protein L22 signature.
257309002234	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
257309002235	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
257309002236	G-X-X-G motif; other site
257309002237	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
257309002238	HMMPfam hit to PF00417, Ribosomal protein S3, N-terminal domain.
257309002239	ProfileScan hit to PS50823, Type-2 KH domain profile.
257309002240	HMMSmart hit to SM00322, K homology RNA-binding domain
257309002241	HMMPfam hit to PF00013, KH domain
257309002242	HMMPfam hit to PF00189, Ribosomal protein S3, C-terminal domain.
257309002243	ScanRegExp hit to PS00548, Ribosomal protein S3 signature.
257309002244	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
257309002245	23S rRNA interface [nucleotide binding]; other site
257309002246	5S rRNA interface [nucleotide binding]; other site
257309002247	putative antibiotic binding site [chemical binding]; other site
257309002248	L25 interface [polypeptide binding]; other site
257309002249	L27 interface [polypeptide binding]; other site
257309002250	HMMPfam hit to PF00252, Ribosomal protein L16
257309002251	FPrintScan hit to PR00060, Ribosomal protein L16 signature
257309002252	FPrintScan hit to PR00060, Ribosomal protein L16 signature
257309002253	FPrintScan hit to PR00060, Ribosomal protein L16 signature
257309002254	ScanRegExp hit to PS00701, Ribosomal protein L16 signature 2.
257309002255	FPrintScan hit to PR00060, Ribosomal protein L16 signature
257309002256	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
257309002257	putative translocon interaction site; other site
257309002258	23S rRNA interface [nucleotide binding]; other site
257309002259	signal recognition particle (SRP54) interaction site; other site
257309002260	L23 interface [polypeptide binding]; other site
257309002261	trigger factor interaction site; other site
257309002262	HMMPfam hit to PF00831, Ribosomal L29 protein
257309002263	ScanRegExp hit to PS00579, Ribosomal protein L29 signature.
257309002264	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
257309002265	BlastProDom hit to PD001295, PD001295; HMMPfam hit to PF00366, Ribosomal protein S17
257309002266	FPrintScan hit to PR00973, Ribosomal protein S17 family signature
257309002267	ScanRegExp hit to PS00056, Ribosomal protein S17 signature.
257309002268	FPrintScan hit to PR00973, Ribosomal protein S17 family signature
257309002269	FPrintScan hit to PR00973, Ribosomal protein S17 family signature
257309002270	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
257309002271	HlyD family secretion protein; Region: HlyD_3; pfam13437
257309002272	ProfileScan hit to PS50310, Alanine-rich region.
257309002273	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309002274	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
257309002275	Walker A/P-loop; other site
257309002276	ATP binding site [chemical binding]; other site
257309002277	Q-loop/lid; other site
257309002278	ABC transporter signature motif; other site
257309002279	Walker B; other site
257309002280	D-loop; other site
257309002281	H-loop/switch region; other site
257309002282	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002283	HMMPfam hit to PF00005, ABC transporter
257309002284	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002285	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002286	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002287	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002288	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
257309002289	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
257309002290	FtsX-like permease family; Region: FtsX; pfam02687
257309002291	4 probable transmembrane helices predicted for DIP0485 by TMHMM2.0
257309002292	HMMPfam hit to PF02687, Predicted permease
257309002293	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
257309002294	BlastProDom hit to PD001093, PD001093; HMMPfam hit to PF00238, Ribosomal protein L14p/L23e
257309002295	ScanRegExp hit to PS00049, Ribosomal protein L14 signature.
257309002296	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
257309002297	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
257309002298	RNA binding site [nucleotide binding]; other site
257309002299	BlastProDom hit to PD001677, PD001677
257309002300	HMMPfam hit to PF00467, KOW motif
257309002301	ScanRegExp hit to PS01108, Ribosomal protein L24 signature.
257309002302	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
257309002303	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
257309002304	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
257309002305	HMMPfam hit to PF00281, Ribosomal protein L5
257309002306	BlastProDom hit to PD001076, PD001076
257309002307	HMMPfam hit to PF00673, ribosomal L5P family C-terminus
257309002308	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
257309002309	serine transporter; Region: stp; TIGR00814
257309002310	ProfileScan hit to PS50286, Permeases for amino acids and related compounds, family II.
257309002311	11 probable transmembrane helices predicted for DIP0489 by TMHMM2.0
257309002312	FPrintScan hit to PR00166, Aromatic amino acid permease signature
257309002313	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309002314	FPrintScan hit to PR00166, Aromatic amino acid permease signature
257309002315	FPrintScan hit to PR00166, Aromatic amino acid permease signature
257309002316	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002317	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
257309002318	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
257309002319	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
257309002320	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
257309002321	active site
257309002322	homotetramer interface [polypeptide binding]; other site
257309002323	homodimer interface [polypeptide binding]; other site
257309002324	Potential twin-arginine recognition motif RRSFLG
257309002325	FPrintScan hit to PR00139, Asparaginase/glutaminase signature
257309002326	ScanRegExp hit to PS00144, Asparaginase / glutaminase active site signature 1.
257309002327	HMMPfam hit to PF00710, Asparaginase
257309002328	FPrintScan hit to PR00139, Asparaginase/glutaminase signature
257309002329	FPrintScan hit to PR00139, Asparaginase/glutaminase signature
257309002330	molybdopterin biosynthesis protein MoeB; Validated; Region: PRK05597
257309002331	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
257309002332	ATP binding site [chemical binding]; other site
257309002333	substrate interface [chemical binding]; other site
257309002334	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
257309002335	active site residue [active]
257309002336	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309002337	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309002338	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature
257309002339	ProfileScan hit to PS50204, UBA/THIF-type NAD binding fold.
257309002340	HMMPfam hit to PF00899, ThiF family
257309002341	ProfileScan hit to PS50205, NAD binding site.
257309002342	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature
257309002343	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
257309002344	MPT binding site; other site
257309002345	trimer interface [polypeptide binding]; other site
257309002346	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
257309002347	MoaE homodimer interface [polypeptide binding]; other site
257309002348	MoaD interaction [polypeptide binding]; other site
257309002349	active site residues [active]
257309002350	HMMPfam hit to PF02391, Molydopterin converting factor subunit 2
257309002351	BlastProDom hit to PD002460, PD002460
257309002352	ScanRegExp hit to PS01078, Molybdenum cofactor biosynthesis proteins signature 1.
257309002353	Predicted transcriptional regulator [Transcription]; Region: COG2345
257309002354	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
257309002355	DNA binding residues [nucleotide binding]
257309002356	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
257309002357	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309002358	dimer interface [polypeptide binding]; other site
257309002359	conserved gate region; other site
257309002360	putative PBP binding loops; other site
257309002361	ABC-ATPase subunit interface; other site
257309002362	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309002363	ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: ModC; COG4148
257309002364	Walker A/P-loop; other site
257309002365	ATP binding site [chemical binding]; other site
257309002366	Q-loop/lid; other site
257309002367	ABC transporter signature motif; other site
257309002368	Walker B; other site
257309002369	D-loop; other site
257309002370	H-loop/switch region; other site
257309002371	TOBE domain; Region: TOBE; cl01440
257309002372	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002373	HMMPfam hit to PF00005, ABC transporter
257309002374	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002375	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002376	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002377	7 probable transmembrane helices predicted for DIP0495 by TMHMM2.0
257309002378	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309002379	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309002380	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
257309002381	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
257309002382	Nitrate reductase gamma subunit; Region: Nitrate_red_gam; pfam02665
257309002383	HMMPfam hit to PF02665, Nitrate reductase gamma subunit
257309002384	5 probable transmembrane helices predicted for DIP0497 by TMHMM2.0
257309002385	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
257309002386	HMMPfam hit to PF02613, Nitrate reductase delta subunit
257309002387	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
257309002388	ScanRegExp hit to PS00190, Cytochrome c family heme-binding site signature.
257309002389	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
257309002390	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
257309002391	[4Fe-4S] binding site [ion binding]; other site
257309002392	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
257309002393	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
257309002394	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
257309002395	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
257309002396	molybdopterin cofactor binding site; other site
257309002397	HMMPfam hit to PF01568, Molydopterin dinucleotide binding domain
257309002398	HMMPfam hit to PF00384, Molybdopterin oxidoreductase
257309002399	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309002400	ScanRegExp hit to PS00490, Prokaryotic molybdopterin oxidoreductases signature 2.
257309002401	HMMPfam hit to PF00384, Molybdopterin oxidoreductase
257309002402	ScanRegExp hit to PS00551, Prokaryotic molybdopterin oxidoreductases signature 1.
257309002403	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
257309002404	12 probable transmembrane helices predicted for DIP0501 by TMHMM2.0
257309002405	ScanRegExp hit to PS00030, Eukaryotic RNA Recognition Motif (RRM) RNP-1 region signature.
257309002406	nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886
257309002407	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309002408	putative substrate translocation pore; other site
257309002409	HMMPfam hit to PF00083, Sugar (and other) transporter
257309002410	12 probable transmembrane helices predicted for DIP0502 by TMHMM2.0
257309002411	Predicted helix-turn-helix motif with score 1078 (+2.86 SD) at aa 345-366, sequence LLIFSLGCAMGVGKAAVYKHIP
257309002412	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
257309002413	MPT binding site; other site
257309002414	trimer interface [polypeptide binding]; other site
257309002415	BlastProDom hit to PD002460, PD002460
257309002416	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
257309002417	GTP binding site; other site
257309002418	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
257309002419	trimer interface [polypeptide binding]; other site
257309002420	dimer interface [polypeptide binding]; other site
257309002421	putative active site [active]
257309002422	HMMPfam hit to PF01967, MoaC family
257309002423	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
257309002424	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
257309002425	dimer interface [polypeptide binding]; other site
257309002426	putative functional site; other site
257309002427	putative MPT binding site; other site
257309002428	HMMPfam hit to PF00994, Molybdenum cofactor biosynthesis protein
257309002429	BlastProDom hit to PD002460, PD002460
257309002430	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
257309002431	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309002432	FeS/SAM binding site; other site
257309002433	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
257309002434	HMMPfam hit to PF01444, moaA / nifB / pqqE family
257309002435	ScanRegExp hit to PS00136, Serine proteases, subtilase, aspartic acid active site.
257309002436	ScanRegExp hit to PS01305, moaA / nifB / pqqE family signature.
257309002437	Pseudogene. Similar to N-terminal region of Pasteurella multocida hypothetical protein PM1540 TR:Q9CKR6 (EMBL:AE006190) (309 aa) fasta scores: E(): 5.9e-13, 29.66% id in 236 aa. Contains two frameshifts at residues 77 and 160;Conserved hypothetical protein (pseudogene; partial)
257309002438	1 probable transmembrane helix predicted for DIP0508 by TMHMM2.0
257309002439	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
257309002440	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
257309002441	inhibitor site; inhibition site
257309002442	active site
257309002443	dimer interface [polypeptide binding]; other site
257309002444	catalytic residue [active]
257309002445	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase
257309002446	BlastProDom hit to PD001859, PD001859
257309002447	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309002448	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309002449	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309002450	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
257309002451	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309002452	Walker A/P-loop; other site
257309002453	ATP binding site [chemical binding]; other site
257309002454	Q-loop/lid; other site
257309002455	ABC transporter signature motif; other site
257309002456	Walker B; other site
257309002457	D-loop; other site
257309002458	H-loop/switch region; other site
257309002459	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
257309002460	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002461	HMMPfam hit to PF00005, ABC transporter
257309002462	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002463	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002464	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002465	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002466	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
257309002467	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309002468	dimer interface [polypeptide binding]; other site
257309002469	conserved gate region; other site
257309002470	putative PBP binding loops; other site
257309002471	ABC-ATPase subunit interface; other site
257309002472	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
257309002473	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309002474	Walker A/P-loop; other site
257309002475	ATP binding site [chemical binding]; other site
257309002476	Q-loop/lid; other site
257309002477	ABC transporter signature motif; other site
257309002478	Walker B; other site
257309002479	D-loop; other site
257309002480	H-loop/switch region; other site
257309002481	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
257309002482	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002483	HMMPfam hit to PF00005, ABC transporter
257309002484	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002485	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002486	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002487	ScanRegExp hit to PS00589, PTS HPR component serine phosphorylation site signature.
257309002488	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002489	5 probable transmembrane helices predicted for DIP0513 by TMHMM2.0
257309002490	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309002491	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
257309002492	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309002493	dimer interface [polypeptide binding]; other site
257309002494	conserved gate region; other site
257309002495	putative PBP binding loops; other site
257309002496	ABC-ATPase subunit interface; other site
257309002497	6 probable transmembrane helices predicted for DIP0514 by TMHMM2.0
257309002498	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309002499	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309002500	TAT (twin-arginine translocation) pathway signal sequence; Region: TAT_signal; pfam10518
257309002501	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
257309002502	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
257309002503	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309002504	Potential twin-arginine recognition motif RRDFFK
257309002505	Transcriptional regulators [Transcription]; Region: FadR; COG2186
257309002506	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309002507	DNA-binding site [nucleotide binding]; DNA binding site
257309002508	FCD domain; Region: FCD; pfam07729
257309002509	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family; HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309002510	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309002511	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309002512	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309002513	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
257309002514	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
257309002515	nucleotide binding site [chemical binding]; other site
257309002516	HMMPfam hit to PF00480, ROK family
257309002517	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
257309002518	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
257309002519	putative active site cavity [active]
257309002520	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309002521	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
257309002522	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
257309002523	active site
257309002524	dimer interface [polypeptide binding]; other site
257309002525	HMMPfam hit to PF02612, N-acetylglucosamine-6-phosphate deacetylase
257309002526	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
257309002527	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
257309002528	active site
257309002529	trimer interface [polypeptide binding]; other site
257309002530	allosteric site; other site
257309002531	active site lid [active]
257309002532	hexamer (dimer of trimers) interface [polypeptide binding]; other site
257309002533	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
257309002534	Htaa; Region: HtaA; pfam04213
257309002535	1 probable transmembrane helix predicted for DIP0522 by TMHMM2.0
257309002536	1 probable transmembrane helix predicted for DIP0523 by TMHMM2.0
257309002537	Predicted helix-turn-helix motif with score 984 (+2.54 SD) at aa 259-280, sequence HNRQALATSLPMPAPTVSVPLD
257309002538	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
257309002539	HMMPfam hit to PF00410, Ribosomal protein S8
257309002540	BlastProDom hit to PD001098, PD001098
257309002541	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
257309002542	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
257309002543	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
257309002544	HMMPfam hit to PF00347, Ribosomal protein L6
257309002545	FPrintScan hit to PR00059, Ribosomal protein L6 signature
257309002546	BlastProDom hit to PD002236, PD002236
257309002547	FPrintScan hit to PR00059, Ribosomal protein L6 signature
257309002548	FPrintScan hit to PR00059, Ribosomal protein L6 signature
257309002549	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
257309002550	5S rRNA interface [nucleotide binding]; other site
257309002551	L27 interface [polypeptide binding]; other site
257309002552	23S rRNA interface [nucleotide binding]; other site
257309002553	L5 interface [polypeptide binding]; other site
257309002554	HMMPfam hit to PF00861, Ribosomal L18p/L5e family
257309002555	BlastProDom hit to PD001394, PD001394
257309002556	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
257309002557	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
257309002558	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
257309002559	HMMPfam hit to PF00333, Ribosomal protein S5
257309002560	ScanRegExp hit to PS00585, Ribosomal protein S5 signature.
257309002561	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
257309002562	23S rRNA binding site [nucleotide binding]; other site
257309002563	HMMPfam hit to PF00327, Ribosomal protein L30p/L7e
257309002564	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
257309002565	HMMPfam hit to PF01305, Ribosomal protein L15 amino terminal region
257309002566	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002567	HMMPfam hit to PF00256, Ribosomal protein L15
257309002568	ScanRegExp hit to PS00475, Ribosomal protein L15 signature.
257309002569	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
257309002570	HMMPfam hit to PF01226, Formate/nitrite transporter
257309002571	6 probable transmembrane helices predicted for DIP0530 by TMHMM2.0
257309002572	FdhD/NarQ family; Region: FdhD-NarQ; cl00659
257309002573	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins; Region: AmyAc_OligoGlu_TS; cd11332
257309002574	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
257309002575	active site
257309002576	catalytic site [active]
257309002577	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309002578	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
257309002579	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
257309002580	active site
257309002581	catalytic site [active]
257309002582	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309002583	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
257309002584	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
257309002585	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein
257309002586	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309002587	dimer interface [polypeptide binding]; other site
257309002588	conserved gate region; other site
257309002589	putative PBP binding loops; other site
257309002590	ABC-ATPase subunit interface; other site
257309002591	8 probable transmembrane helices predicted for DIP0535 by TMHMM2.0
257309002592	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309002593	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309002594	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
257309002595	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309002596	dimer interface [polypeptide binding]; other site
257309002597	conserved gate region; other site
257309002598	putative PBP binding loops; other site
257309002599	ABC-ATPase subunit interface; other site
257309002600	5 probable transmembrane helices predicted for DIP0536 by TMHMM2.0
257309002601	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309002602	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309002603	5 probable transmembrane helices predicted for DIP0537 by TMHMM2.0
257309002604	Domain of unknown function (DUF4032); Region: DUF4032; pfam13224
257309002605	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
257309002606	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
257309002607	Walker A/P-loop; other site
257309002608	ATP binding site [chemical binding]; other site
257309002609	Q-loop/lid; other site
257309002610	ABC transporter signature motif; other site
257309002611	Walker B; other site
257309002612	D-loop; other site
257309002613	H-loop/switch region; other site
257309002614	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002615	HMMPfam hit to PF00005, ABC transporter
257309002616	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002617	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002618	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002619	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002620	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
257309002621	SecY translocase; Region: SecY; pfam00344
257309002622	10 probable transmembrane helices predicted for DIP0540 by TMHMM2.0
257309002623	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002624	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002625	HMMPfam hit to PF00344, eubacterial secY protein
257309002626	ScanRegExp hit to PS00755, Protein secY signature 1.
257309002627	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002628	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002629	ScanRegExp hit to PS00756, Protein secY signature 2.
257309002630	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002631	ScanRegExp hit to PS00095, C-5 cytosine-specific DNA methylases C-terminal signature.
257309002632	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002633	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002634	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002635	FPrintScan hit to PR00303, Preprotein translocase SecY subunit signature
257309002636	adenylate kinase; Reviewed; Region: adk; PRK00279
257309002637	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
257309002638	AMP-binding site [chemical binding]; other site
257309002639	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
257309002640	FPrintScan hit to PR00094, Adenylate kinase signature
257309002641	HMMPfam hit to PF00406, Adenylate kinase
257309002642	BlastProDom hit to PD000657, PD000657
257309002643	FPrintScan hit to PR00094, Adenylate kinase signature
257309002644	FPrintScan hit to PR00094, Adenylate kinase signature
257309002645	ScanRegExp hit to PS00113, Adenylate kinase signature.
257309002646	FPrintScan hit to PR00094, Adenylate kinase signature
257309002647	FPrintScan hit to PR00094, Adenylate kinase signature
257309002648	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
257309002649	active site
257309002650	HMMPfam hit to PF00557, metallopeptidase M24
257309002651	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309002652	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309002653	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309002654	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309002655	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
257309002656	catalytic site [active]
257309002657	BNR repeat-like domain; Region: BNR_2; pfam13088
257309002658	Asp-box motif; other site
257309002659	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002660	HMMPfam hit to PF02012, BNR repeat
257309002661	HMMPfam hit to PF02012, BNR repeat
257309002662	HMMPfam hit to PF02012, BNR repeat
257309002663	HMMPfam hit to PF02012, BNR repeat
257309002664	HMMPfam hit to PF02012, BNR repeat
257309002665	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002666	ProfileScan hit to PS50310, Alanine-rich region.
257309002667	1 probable transmembrane helix predicted for DIP0543 by TMHMM2.0
257309002668	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
257309002669	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
257309002670	rRNA binding site [nucleotide binding]; other site
257309002671	predicted 30S ribosome binding site; other site
257309002672	HMMPfam hit to PF00575, S1 RNA binding domain
257309002673	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309002674	ScanRegExp hit to PS00215, Mitochondrial energy transfer proteins signature.
257309002675	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
257309002676	30S ribosomal protein S13; Region: bact_S13; TIGR03631
257309002677	HMMPfam hit to PF00416, Ribosomal protein S13/S18
257309002678	ProfileScan hit to PS50159, Ribosomal protein S13/S18 family.
257309002679	BlastProDom hit to PD001363, PD001363
257309002680	ScanRegExp hit to PS00646, Ribosomal protein S13 signature.
257309002681	30S ribosomal protein S11; Validated; Region: PRK05309
257309002682	BlastProDom hit to PD001010, PD001010
257309002683	HMMPfam hit to PF00411, Ribosomal protein S11
257309002684	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
257309002685	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
257309002686	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
257309002687	RNA binding surface [nucleotide binding]; other site
257309002688	HMMPfam hit to PF00163, Ribosomal protein S4/S9 N-terminal domain
257309002689	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002690	ScanRegExp hit to PS00632, Ribosomal protein S4 signature.
257309002691	HMMSmart hit to SM00363, S4 RNA-binding domain
257309002692	HMMPfam hit to PF01479, S4 domain
257309002693	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
257309002694	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
257309002695	alphaNTD - beta interaction site [polypeptide binding]; other site
257309002696	alphaNTD homodimer interface [polypeptide binding]; other site
257309002697	alphaNTD - beta' interaction site [polypeptide binding]; other site
257309002698	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
257309002699	BlastProDom hit to PD001179, PD001179
257309002700	HMMPfam hit to PF01000, Bacterial RNA polymerase, alpha chain
257309002701	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002702	HMMPfam hit to PF03118
257309002703	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
257309002704	BlastProDom hit to PD004277, PD004277
257309002705	HMMPfam hit to PF01196, Ribosomal protein L17
257309002706	ScanRegExp hit to PS01167, Ribosomal protein L17 signature.
257309002707	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
257309002708	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
257309002709	dimerization interface 3.5A [polypeptide binding]; other site
257309002710	active site
257309002711	HMMPfam hit to PF01416, tRNA pseudouridine synthase
257309002712	Protein of unknown function (DUF690); Region: DUF690; cl04939
257309002713	1 probable transmembrane helix predicted for DIP0552 by TMHMM2.0
257309002714	ESAT-6 gene cluster. Conserved genomic organisation as in Mycobacterium tuberculosis ESAT-6 gene cluster region 4: Encode  T-cell antigens that lack detectable secretion signals (Ref: Gey van Pittius, et al. Genome Biology (2001), 2(10):research 0044.1-0044.18)
257309002715	TIGR02611 family protein; Region: TIGR02611
257309002716	3 probable transmembrane helices predicted for DIP0553 by TMHMM2.0
257309002717	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
257309002718	active site
257309002719	catalytic residues [active]
257309002720	FPrintScan hit to PR00723, Subtilisin serine protease (S8) signature
257309002721	HMMPfam hit to PF00082, Subtilase
257309002722	ScanRegExp hit to PS00137, Serine proteases, subtilase, histidine active site.
257309002723	FPrintScan hit to PR00723, Subtilisin serine protease (S8) signature
257309002724	FPrintScan hit to PR00723, Subtilisin serine protease (S8) signature
257309002725	ScanRegExp hit to PS00136, Serine proteases, subtilase, aspartic acid active site.
257309002726	type VII secretion integral membrane protein EccD; Region: T7SS_EccD; TIGR03920
257309002727	11 probable transmembrane helices predicted for DIP0555 by TMHMM2.0
257309002728	potential sortase anchor site LPNTG
257309002729	type VII secretion protein EccCa; Region: T7SS_EccC_a; TIGR03924
257309002730	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
257309002731	type VII secretion protein EccCb; Region: T7SS_EccC_b; TIGR03925
257309002732	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
257309002733	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
257309002734	1 probable transmembrane helix predicted for DIP0556 by TMHMM2.0
257309002735	ProfileScan hit to PS50320, Methionine-rich region.
257309002736	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002737	HMMPfam hit to PF01580, FtsK/SpoIIIE family
257309002738	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002739	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002740	HMMPfam hit to PF01580, FtsK/SpoIIIE family
257309002741	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002742	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002743	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002744	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002745	type VII secretion-associated protein, Rv3446c family, C-terminal domain; Region: T7SS_Rv3446c; TIGR03931
257309002746	1 probable transmembrane helix predicted for DIP0557 by TMHMM2.0
257309002747	WXG100 family type VII secretion target; Region: WXG100_ESAT6; TIGR03930
257309002748	ESAT-6-like WXG100 family protein conserved motif (WXG)
257309002749	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4842
257309002750	ESAT-6-like WXG100 family protein conserved motif (WXG)
257309002751	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
257309002752	23S rRNA interface [nucleotide binding]; other site
257309002753	L3 interface [polypeptide binding]; other site
257309002754	HMMPfam hit to PF00572, Ribosomal protein L13
257309002755	BlastProDom hit to PD001791, PD001791
257309002756	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
257309002757	BlastProDom hit to PD001627, PD001627; HMMPfam hit to PF00380, Ribosomal protein S9/S16
257309002758	ScanRegExp hit to PS00360, Ribosomal protein S9 signature.
257309002759	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14318
257309002760	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
257309002761	active site
257309002762	substrate binding site [chemical binding]; other site
257309002763	metal binding site [ion binding]; metal-binding site
257309002764	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
257309002765	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309002766	ScanRegExp hit to PS00710, Phosphoglucomutase and phosphomannomutase phosphoserine signature.
257309002767	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
257309002768	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309002769	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309002770	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
257309002771	ProfileScan hit to PS50239, Phospholipid and glycerol acyltransferase (from 'motifs_6.msf').
257309002772	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-terminal domain
257309002773	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002774	ProfileScan hit to PS50099, Proline-rich region.
257309002775	FPrintScan hit to PR01217, Proline rich extensin signature
257309002776	ProfileScan hit to PS50325, Threonine-rich region.
257309002777	1 probable transmembrane helix predicted for DIP0565 by TMHMM2.0
257309002778	ProfileScan hit to PS50099, Proline-rich region.
257309002779	FPrintScan hit to PR01217, Proline rich extensin signature
257309002780	FPrintScan hit to PR01217, Proline rich extensin signature
257309002781	FPrintScan hit to PR01217, Proline rich extensin signature
257309002782	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
257309002783	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309002784	alanine racemase; Reviewed; Region: alr; PRK00053
257309002785	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
257309002786	active site
257309002787	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
257309002788	dimer interface [polypeptide binding]; other site
257309002789	substrate binding site [chemical binding]; other site
257309002790	catalytic residues [active]
257309002791	FPrintScan hit to PR00992, Alanine racemase signature
257309002792	HMMPfam hit to PF00842, Alanine racemase
257309002793	FPrintScan hit to PR00992, Alanine racemase signature
257309002794	ScanRegExp hit to PS00024, Hemopexin domain signature.
257309002795	FPrintScan hit to PR00992, Alanine racemase signature
257309002796	FPrintScan hit to PR00992, Alanine racemase signature
257309002797	FPrintScan hit to PR00992, Alanine racemase signature
257309002798	FPrintScan hit to PR00992, Alanine racemase signature
257309002799	FPrintScan hit to PR00992, Alanine racemase signature
257309002800	FPrintScan hit to PR00992, Alanine racemase signature
257309002801	FPrintScan hit to PR00992, Alanine racemase signature
257309002802	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
257309002803	HMMPfam hit to PF02367, Uncharacterised P-loop hydrolase UPF0079
257309002804	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002805	Predicted permease [General function prediction only]; Region: COG2985
257309002806	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
257309002807	TrkA-C domain; Region: TrkA_C; pfam02080
257309002808	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
257309002809	10 probable transmembrane helices predicted for DIP0570 by TMHMM2.0
257309002810	HMMPfam hit to PF02080, Potassium channel
257309002811	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
257309002812	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
257309002813	Glycoprotease family; Region: Peptidase_M22; pfam00814
257309002814	BlastProDom hit to PD002367, PD002367
257309002815	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309002816	Coenzyme A binding pocket [chemical binding]; other site
257309002817	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309002818	UGMP family protein; Validated; Region: PRK09604
257309002819	HMMPfam hit to PF00814, Glycoprotease
257309002820	BlastProDom hit to PD002367, PD002367
257309002821	FPrintScan hit to PR00789, O-sialoglycoprotein endopeptidase (M22) metallo-protease signature
257309002822	FPrintScan hit to PR00789, O-sialoglycoprotein endopeptidase (M22) metallo-protease signature
257309002823	ScanRegExp hit to PS01016, Glycoprotease signature.
257309002824	FPrintScan hit to PR00789, O-sialoglycoprotein endopeptidase (M22) metallo-protease signature
257309002825	FPrintScan hit to PR00789, O-sialoglycoprotein endopeptidase (M22) metallo-protease signature
257309002826	FPrintScan hit to PR00789, O-sialoglycoprotein endopeptidase (M22) metallo-protease signature
257309002827	FPrintScan hit to PR00789, O-sialoglycoprotein endopeptidase (M22) metallo-protease signature
257309002828	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
257309002829	oligomerisation interface [polypeptide binding]; other site
257309002830	mobile loop; other site
257309002831	roof hairpin; other site
257309002832	HMMPfam hit to PF00166, Chaperonin 10 Kd subunit
257309002833	BlastProDom hit to PD000566, PD000566
257309002834	ScanRegExp hit to PS00681, Chaperonins cpn10 signature.
257309002835	FPrintScan hit to PR00297, 10kDa chaperonin signature
257309002836	FPrintScan hit to PR00297, 10kDa chaperonin signature
257309002837	FPrintScan hit to PR00297, 10kDa chaperonin signature
257309002838	FPrintScan hit to PR00297, 10kDa chaperonin signature
257309002839	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
257309002840	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
257309002841	ring oligomerisation interface [polypeptide binding]; other site
257309002842	ATP/Mg binding site [chemical binding]; other site
257309002843	stacking interactions; other site
257309002844	hinge regions; other site
257309002845	HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family
257309002846	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309002847	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309002848	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309002849	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309002850	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309002851	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309002852	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309002853	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309002854	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309002855	ScanRegExp hit to PS00296, Chaperonins cpn60 signature.
257309002856	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309002857	ProfileScan hit to PS50316, Histidine-rich region.
257309002858	RNA polymerase sigma factor SigD; Reviewed; Region: PRK09648
257309002859	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309002860	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309002861	DNA binding residues [nucleotide binding]
257309002862	Predicted helix-turn-helix motif with score 1323 (+3.69 SD) at aa 151-172, sequence LSAEETAEIVGSTPGAVRVAQH
257309002863	1 probable transmembrane helix predicted for DIP0578 by TMHMM2.0
257309002864	ProfileScan hit to PS50325, Threonine-rich region.
257309002865	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
257309002866	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
257309002867	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
257309002868	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
257309002869	active site
257309002870	HMMPfam hit to PF01574, IMP dehydrogenase / GMP reductase N terminus
257309002871	HMMPfam hit to PF00571, CBS domain
257309002872	HMMSmart hit to SM00116, Domain in cystathionine beta-synthase and other proteins.
257309002873	ProfileScan hit to PS50147, SNF4 repeat.
257309002874	HMMPfam hit to PF00571, CBS domain
257309002875	HMMSmart hit to SM00116, Domain in cystathionine beta-synthase and other proteins.
257309002876	ProfileScan hit to PS50147, SNF4 repeat.
257309002877	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase C terminus
257309002878	ScanRegExp hit to PS00487, IMP dehydrogenase / GMP reductase signature.
257309002879	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309002880	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK08649
257309002881	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
257309002882	phosphate binding site [ion binding]; other site
257309002883	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase C terminus
257309002884	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309002885	iron uptake system
257309002886	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
257309002887	siderophore binding site; other site
257309002888	1 probable transmembrane helix predicted for DIP0582 by TMHMM2.0
257309002889	HMMPfam hit to PF01497, Periplasmic binding protein
257309002890	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002891	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309002892	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
257309002893	dimer interface [polypeptide binding]; other site
257309002894	putative PBP binding regions; other site
257309002895	ABC-ATPase subunit  interface; other site
257309002896	8 probable transmembrane helices predicted for DIP0583 by TMHMM2.0
257309002897	HMMPfam hit to PF01032, FecCD transport family
257309002898	BlastProDom hit to PD001557, PD001557
257309002899	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
257309002900	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309002901	ABC-ATPase subunit  interface; other site
257309002902	dimer interface [polypeptide binding]; other site
257309002903	putative PBP binding regions; other site
257309002904	9 probable transmembrane helices predicted for DIP0584 by TMHMM2.0
257309002905	HMMPfam hit to PF01032, FecCD transport family
257309002906	BlastProDom hit to PD001557, PD001557
257309002907	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
257309002908	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
257309002909	Walker A/P-loop; other site
257309002910	ATP binding site [chemical binding]; other site
257309002911	Q-loop/lid; other site
257309002912	ABC transporter signature motif; other site
257309002913	Walker B; other site
257309002914	D-loop; other site
257309002915	H-loop/switch region; other site
257309002916	HMMPfam hit to PF00013, KH domain
257309002917	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309002918	HMMPfam hit to PF00005, ABC transporter
257309002919	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309002920	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309002921	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309002922	ScanRegExp hit to PS00211, ABC transporters family signature.
257309002923	IucA / IucC family; Region: IucA_IucC; pfam04183
257309002924	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
257309002925	IucA / IucC family; Region: IucA_IucC; pfam04183
257309002926	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
257309002927	H+ Antiporter protein; Region: 2A0121; TIGR00900
257309002928	10 probable transmembrane helices predicted for DIP0587 by TMHMM2.0
257309002929	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309002930	4 probable transmembrane helices predicted for DIP0588 by TMHMM2.0
257309002931	Threonine/homoserine efflux transporter [Amino acid transport and metabolism]; Region: rhtA; COG5006
257309002932	EamA-like transporter family; Region: EamA; pfam00892
257309002933	10 probable transmembrane helices predicted for DIP0589 by TMHMM2.0
257309002934	HMMPfam hit to PF00892, Integral membrane protein DUF6
257309002935	Pseudogene. Similar to central parts of Deinococcus radiodurans hypothetical 77.5 kDa protein DR2265 TR:Q9RS62 (EMBL:AE002059) (725 aa) fasta scores: E(): 9.6e-10, 34.54% id in 165 aa. Presents an internal stop codon;Conserved hypothetical protein (pseudogene)
257309002936	1 probable transmembrane helix predicted for DIP0590 by TMHMM2.0
257309002937	1 probable transmembrane helix predicted for DIP0591 by TMHMM2.0
257309002938	GMP synthase; Reviewed; Region: guaA; PRK00074
257309002939	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
257309002940	AMP/PPi binding site [chemical binding]; other site
257309002941	candidate oxyanion hole; other site
257309002942	catalytic triad [active]
257309002943	potential glutamine specificity residues [chemical binding]; other site
257309002944	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
257309002945	ATP Binding subdomain [chemical binding]; other site
257309002946	Ligand Binding sites [chemical binding]; other site
257309002947	Dimerization subdomain; other site
257309002948	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309002949	HMMPfam hit to PF00117, Glutamine amidotransferase class-I
257309002950	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309002951	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309002952	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309002953	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature; ScanRegExp hit to PS00442, Glutamine amidotransferases class-I active site.
257309002954	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309002955	HMMPfam hit to PF00958, GMP synthase C terminal domain
257309002956	PspC domain; Region: PspC; pfam04024
257309002957	3 probable transmembrane helices predicted for DIP0598 by TMHMM2.0
257309002958	PspC domain; Region: PspC; pfam04024
257309002959	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
257309002960	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
257309002961	ATP binding site [chemical binding]; other site
257309002962	Mg2+ binding site [ion binding]; other site
257309002963	G-X-G motif; other site
257309002964	6 probable transmembrane helices predicted for DIP0599 by TMHMM2.0
257309002965	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase
257309002966	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
257309002967	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309002968	active site
257309002969	phosphorylation site [posttranslational modification]
257309002970	intermolecular recognition site; other site
257309002971	dimerization interface [polypeptide binding]; other site
257309002972	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
257309002973	DNA binding residues [nucleotide binding]
257309002974	dimerization interface [polypeptide binding]; other site
257309002975	HMMPfam hit to PF00072, Response regulator receiver domain
257309002976	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309002977	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309002978	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family
257309002979	HMMSmart hit to SM00421, helix_turn_helix, Lux Regulon
257309002980	ProfileScan hit to PS50043, Helix-turn-helix domain, luxR and related types (substantial overlap with lysR type).
257309002981	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309002982	ScanRegExp hit to PS00622, Bacterial regulatory proteins, luxR family signature.
257309002983	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309002984	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309002985	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309002986	intersubunit interface [polypeptide binding]; other site
257309002987	3 probable transmembrane helices predicted for DIP0602 by TMHMM2.0
257309002988	DNA Polymerase Y-family; Region: PolY_like; cd03468
257309002989	active site
257309002990	DNA binding site [nucleotide binding]
257309002991	ProfileScan hit to PS50173, UMUC domain (DNA-repair).
257309002992	TRX-like [2Fe-2S] Ferredoxin (Fd) family, Sucrase subfamily; composed of proteins with similarity to a novel plant enzyme, isolated from potato, which contains a Fd-like domain and exhibits sucrolytic activity. The putative active site of the Fd-like...; Region: TRX_Fd_Sucrase; cd03062
257309002993	putative dimer interface [polypeptide binding]; other site
257309002994	putative [2Fe-2S] cluster binding site [ion binding]; other site
257309002995	Mechanosensitive ion channel; Region: MS_channel; pfam00924
257309002996	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
257309002997	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
257309002998	ProfileScan hit to PS50324, Serine-rich region.
257309002999	HMMPfam hit to PF00924, Mechanosensitive ion channel
257309003000	3 probable transmembrane helices predicted for DIP0607 by TMHMM2.0
257309003001	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309003002	dimer interface [polypeptide binding]; other site
257309003003	conserved gate region; other site
257309003004	ABC-ATPase subunit interface; other site
257309003005	5 probable transmembrane helices predicted for DIP0608 by TMHMM2.0
257309003006	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309003007	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309003008	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
257309003009	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
257309003010	Walker A/P-loop; other site
257309003011	ATP binding site [chemical binding]; other site
257309003012	Q-loop/lid; other site
257309003013	ABC transporter signature motif; other site
257309003014	Walker B; other site
257309003015	D-loop; other site
257309003016	H-loop/switch region; other site
257309003017	NIL domain; Region: NIL; cl09633
257309003018	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309003019	HMMPfam hit to PF00005, ABC transporter
257309003020	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309003021	ScanRegExp hit to PS00211, ABC transporters family signature.
257309003022	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309003023	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003024	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
257309003025	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
257309003026	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
257309003027	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
257309003028	error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672
257309003029	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
257309003030	active site
257309003031	PHP Thumb interface [polypeptide binding]; other site
257309003032	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
257309003033	generic binding surface II; other site
257309003034	generic binding surface I; other site
257309003035	HMMSmart hit to SM00481, DNA polymerase alpha chain like domain
257309003036	HMMPfam hit to PF02231, PHP domain N-terminal region
257309003037	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain
257309003038	iron uptake system
257309003039	Uncharacterized conserved protein [Function unknown]; Region: COG3402
257309003040	2 probable transmembrane helices predicted for DIP0613 by TMHMM2.0
257309003041	Predicted membrane protein [Function unknown]; Region: COG3428
257309003042	Bacterial PH domain; Region: DUF304; pfam03703
257309003043	Bacterial PH domain; Region: DUF304; pfam03703
257309003044	Bacterial PH domain; Region: DUF304; pfam03703
257309003045	3 probable transmembrane helices predicted for DIP0614 by TMHMM2.0
257309003046	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309003047	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
257309003048	intersubunit interface [polypeptide binding]; other site
257309003049	1 probable transmembrane helix predicted for DIP0615 by TMHMM2.0
257309003050	HMMPfam hit to PF01297, Periplasmic solute binding protein family
257309003051	FPrintScan hit to PR00691, Adhesin B signature
257309003052	FPrintScan hit to PR00690, Adhesin family signature
257309003053	FPrintScan hit to PR00691, Adhesin B signature
257309003054	FPrintScan hit to PR00690, Adhesin family signature
257309003055	FPrintScan hit to PR00691, Adhesin B signature
257309003056	FPrintScan hit to PR00690, Adhesin family signature
257309003057	FPrintScan hit to PR00691, Adhesin B signature
257309003058	FPrintScan hit to PR00691, Adhesin B signature
257309003059	FPrintScan hit to PR00690, Adhesin family signature
257309003060	FPrintScan hit to PR00691, Adhesin B signature
257309003061	FPrintScan hit to PR00690, Adhesin family signature
257309003062	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
257309003063	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
257309003064	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309003065	HMMPfam hit to PF00005, ABC transporter
257309003066	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309003067	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003068	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309003069	ScanRegExp hit to PS00211, ABC transporters family signature.
257309003070	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
257309003071	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309003072	dimer interface [polypeptide binding]; other site
257309003073	putative PBP binding regions; other site
257309003074	ABC-ATPase subunit  interface; other site
257309003075	8 probable transmembrane helices predicted for DIP0617 by TMHMM2.0
257309003076	HMMPfam hit to PF00950, ABC 3 transport family
257309003077	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
257309003078	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
257309003079	ABC-ATPase subunit  interface; other site
257309003080	dimer interface [polypeptide binding]; other site
257309003081	putative PBP binding regions; other site
257309003082	7 probable transmembrane helices predicted for DIP0618 by TMHMM2.0
257309003083	HMMPfam hit to PF00950, ABC 3 transport family
257309003084	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
257309003085	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
257309003086	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
257309003087	This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; Region: FeoA; smart00899
257309003088	HMMSmart hit to SM00529, Helix-turn-helix diphteria tox regulatory element
257309003089	HMMPfam hit to PF02742, Iron dependent repressor, metal binding and dimerisation domain
257309003090	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14193
257309003091	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
257309003092	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
257309003093	homodimer interface [polypeptide binding]; other site
257309003094	NADP binding site [chemical binding]; other site
257309003095	substrate binding site [chemical binding]; other site
257309003096	HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
257309003097	BlastProDom hit to PD002300, PD002300
257309003098	FPrintScan hit to PR00085, Tetrahydrofolate dehydrogenase/cyclohydrolase signature
257309003099	FPrintScan hit to PR00085, Tetrahydrofolate dehydrogenase/cyclohydrolase signature
257309003100	FPrintScan hit to PR00085, Tetrahydrofolate dehydrogenase/cyclohydrolase signature
257309003101	HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
257309003102	FPrintScan hit to PR00085, Tetrahydrofolate dehydrogenase/cyclohydrolase signature
257309003103	FPrintScan hit to PR00085, Tetrahydrofolate dehydrogenase/cyclohydrolase signature
257309003104	FPrintScan hit to PR00085, Tetrahydrofolate dehydrogenase/cyclohydrolase signature
257309003105	Protein of unknown function (DUF3017); Region: DUF3017; pfam11222
257309003106	3 probable transmembrane helices predicted for DIP0621 by TMHMM2.0
257309003107	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309003108	active site
257309003109	HMMPfam hit to PF01844, HNH endonuclease
257309003110	HMMSmart hit to SM00507, HNH nucleases
257309003111	1 probable transmembrane helix predicted for DIP0622 by TMHMM2.0
257309003112	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
257309003113	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
257309003114	HMMPfam hit to PF00561, alpha/beta hydrolase fold
257309003115	3 probable transmembrane helices predicted for DIP0624 by TMHMM2.0
257309003116	heme-related iron uptake system
257309003117	Htaa; Region: HtaA; pfam04213
257309003118	Htaa; Region: HtaA; pfam04213
257309003119	1 probable transmembrane helix predicted for DIP0625 by TMHMM2.0
257309003120	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
257309003121	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
257309003122	intersubunit interface [polypeptide binding]; other site
257309003123	HMMPfam hit to PF01497, Periplasmic binding protein
257309003124	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
257309003125	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309003126	ABC-ATPase subunit  interface; other site
257309003127	dimer interface [polypeptide binding]; other site
257309003128	putative PBP binding regions; other site
257309003129	8 probable transmembrane helices predicted for DIP0627 by TMHMM2.0
257309003130	HMMPfam hit to PF01032, FecCD transport family
257309003131	ProfileScan hit to PS50281, Binding-system dependent bacterial transporters (araH, livH/limM families)
257309003132	BlastProDom hit to PD001557, PD001557
257309003133	ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG4559
257309003134	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
257309003135	Walker A/P-loop; other site
257309003136	ATP binding site [chemical binding]; other site
257309003137	Q-loop/lid; other site
257309003138	ABC transporter signature motif; other site
257309003139	Walker B; other site
257309003140	D-loop; other site
257309003141	H-loop/switch region; other site
257309003142	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309003143	HMMPfam hit to PF00005, ABC transporter
257309003144	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309003145	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003146	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309003147	ScanRegExp hit to PS00211, ABC transporters family signature.
257309003148	Htaa; Region: HtaA; pfam04213
257309003149	1 probable transmembrane helix predicted for DIP0629 by TMHMM2.0
257309003150	O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK05613
257309003151	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
257309003152	homodimer interface [polypeptide binding]; other site
257309003153	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309003154	substrate-cofactor binding pocket; other site
257309003155	catalytic residue [active]
257309003156	HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzyme
257309003157	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
257309003158	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
257309003159	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
257309003160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309003161	putative substrate translocation pore; other site
257309003162	HMMPfam hit to PF00083, Sugar (and other) transporter
257309003163	12 probable transmembrane helices predicted for DIP0632 by TMHMM2.0
257309003164	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
257309003165	putative catalytic site [active]
257309003166	putative metal binding site [ion binding]; other site
257309003167	putative phosphate binding site [ion binding]; other site
257309003168	HMMPfam hit to PF01260, AP endonuclease 1
257309003169	HMMPfam hit to PF01260, AP endonuclease 1
257309003170	2 probable transmembrane helices predicted for DIP0634 by TMHMM2.0
257309003171	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
257309003172	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
257309003173	active site
257309003174	HIGH motif; other site
257309003175	dimer interface [polypeptide binding]; other site
257309003176	KMSKS motif; other site
257309003177	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y)
257309003178	FPrintScan hit to PR01039, Tryptophanyl-tRNA synthetase signature
257309003179	FPrintScan hit to PR01039, Tryptophanyl-tRNA synthetase signature
257309003180	FPrintScan hit to PR01039, Tryptophanyl-tRNA synthetase signature
257309003181	FPrintScan hit to PR01039, Tryptophanyl-tRNA synthetase signature
257309003182	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
257309003183	6 probable transmembrane helices predicted for DIP0636 by TMHMM2.0
257309003184	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
257309003185	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
257309003186	1 probable transmembrane helix predicted for DIP0637 by TMHMM2.0
257309003187	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase
257309003188	FPrintScan hit to PR00725, D-Ala-D-Ala carboxypeptidase 1 (S11) family signature
257309003189	FPrintScan hit to PR00725, D-Ala-D-Ala carboxypeptidase 1 (S11) family signature
257309003190	FPrintScan hit to PR00725, D-Ala-D-Ala carboxypeptidase 1 (S11) family signature
257309003191	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
257309003192	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309003193	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
257309003194	NlpC/P60 family; Region: NLPC_P60; pfam00877
257309003195	HMMPfam hit to PF00877, NLP/P60 family
257309003196	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309003197	active site
257309003198	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309003199	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
257309003200	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309003201	non-specific DNA binding site [nucleotide binding]; other site
257309003202	salt bridge; other site
257309003203	sequence-specific DNA binding site [nucleotide binding]; other site
257309003204	HMMSmart hit to SM00530, Helix-turn-helix XRE-family like proteins, DNA-binding
257309003205	HMMPfam hit to PF01381, Helix-turn-helix
257309003206	Predicted helix-turn-helix motif with score 1855 (+5.50 SD) at aa 38-59, sequence LTQDGLAEIANLSRNQISNLER
257309003207	ProfileScan hit to PS50312, Aspartic acid-rich region.
257309003208	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
257309003209	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like4; cd08014
257309003210	metal binding site [ion binding]; metal-binding site
257309003211	putative dimer interface [polypeptide binding]; other site
257309003212	HMMPfam hit to PF01546, Peptidase M20/M25/M40
257309003213	flavoprotein disulfide reductase; Reviewed; Region: PRK07845
257309003214	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
257309003215	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
257309003216	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase
257309003217	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003218	ProfileScan hit to PS50205, NAD binding site.
257309003219	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309003220	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003221	HMMPfam hit to PF02780, Transketolase, C-terminal domain
257309003222	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003223	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309003224	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003225	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309003226	ProfileScan hit to PS50205, NAD binding site.
257309003227	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309003228	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003229	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309003230	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003231	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003232	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
257309003233	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309003234	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003235	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309003236	pyruvate carboxylase; Reviewed; Region: PRK12999
257309003237	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
257309003238	ATP-grasp domain; Region: ATP-grasp_4; cl17255
257309003239	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
257309003240	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
257309003241	active site
257309003242	catalytic residues [active]
257309003243	metal binding site [ion binding]; metal-binding site
257309003244	homodimer binding site [polypeptide binding]; other site
257309003245	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
257309003246	carboxyltransferase (CT) interaction site; other site
257309003247	biotinylation site [posttranslational modification]; other site
257309003248	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain, N-terminal domain
257309003249	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP binding domain
257309003250	ScanRegExp hit to PS00867, Carbamoyl-phosphate synthase subdomain signature 2.
257309003251	HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain
257309003252	HMMPfam hit to PF00682, HMGL-like
257309003253	HMMPfam hit to PF02436, Conserved carboxylase domain
257309003254	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309003255	ScanRegExp hit to PS00188, Biotin-requiring enzymes attachment site.
257309003256	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cd02749
257309003257	ADP-ribose binding site [chemical binding]; other site
257309003258	HMMPfam hit to PF01661, Appr-1''-p processing enzyme family
257309003259	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
257309003260	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
257309003261	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
257309003262	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
257309003263	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
257309003264	carboxyltransferase (CT) interaction site; other site
257309003265	biotinylation site [posttranslational modification]; other site
257309003266	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309003267	ScanRegExp hit to PS00188, Biotin-requiring enzymes attachment site.
257309003268	HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain
257309003269	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309003270	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP binding domain
257309003271	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309003272	ScanRegExp hit to PS00867, Carbamoyl-phosphate synthase subdomain signature 2.
257309003273	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309003274	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309003275	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain, N-terminal domain
257309003276	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
257309003277	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
257309003278	active site residue [active]
257309003279	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
257309003280	active site residue [active]
257309003281	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309003282	HMMPfam hit to PF00581, Rhodanese-like domain
257309003283	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309003284	ScanRegExp hit to PS00683, Rhodanese C-terminal signature.
257309003285	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309003286	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309003287	HMMPfam hit to PF00581, Rhodanese-like domain
257309003288	ScanRegExp hit to PS00380, Rhodanese signature 1.
257309003289	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
257309003290	11 probable transmembrane helices predicted for DIP0652 by TMHMM2.0
257309003291	Protein of unknown function (DUF3151); Region: DUF3151; pfam11349
257309003292	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
257309003293	active site
257309003294	dimer interface [polypeptide binding]; other site
257309003295	HMMPfam hit to PF02545, Maf-like protein
257309003296	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
257309003297	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
257309003298	substrate binding site [chemical binding]; other site
257309003299	dimer interface [polypeptide binding]; other site
257309003300	ATP binding site [chemical binding]; other site
257309003301	HMMPfam hit to PF00294, pfkB family carbohydrate kinase
257309003302	ScanRegExp hit to PS00584, pfkB family of carbohydrate kinases signature 2.
257309003303	FPrintScan hit to PR00990, Ribokinase signature
257309003304	FPrintScan hit to PR00990, Ribokinase signature
257309003305	FPrintScan hit to PR00990, Ribokinase signature
257309003306	ScanRegExp hit to PS00583, pfkB family of carbohydrate kinases signature 1.
257309003307	FPrintScan hit to PR00990, Ribokinase signature
257309003308	FPrintScan hit to PR00990, Ribokinase signature
257309003309	Transcriptional regulators [Transcription]; Region: PurR; COG1609
257309003310	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
257309003311	DNA binding site [nucleotide binding]
257309003312	domain linker motif; other site
257309003313	Ligand-binding domain of DNA-binding regulatory protein from Corynebacterium glutamicum which has a unique ability to produce significant amounts of L-glutamate directly from cheap sugar and ammonia; Region: PBP1_LacI_like_13; cd06299
257309003314	dimerization interface [polypeptide binding]; other site
257309003315	putative ligand binding site [chemical binding]; other site
257309003316	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar binding domain of the LacI family.
257309003317	HMMSmart hit to SM00354, helix_turn _helix lactose operon repressor, DNA-binding
257309003318	Predicted helix-turn-helix motif with score 1943 (+5.80 SD) at aa 25-46, sequence ITLKDIAADTGLSISTVSRALA
257309003319	Acyl-CoA carboxylase epsilon subunit; Region: ACC_epsilon; pfam13822
257309003320	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
257309003321	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
257309003322	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
257309003323	HMMPfam hit to PF01039, Carboxyl transferase domain
257309003324	1 probable transmembrane helix predicted for DIP0658 by TMHMM2.0
257309003325	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003326	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003327	1 probable transmembrane helix predicted for DIP0659 by TMHMM2.0
257309003328	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
257309003329	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
257309003330	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
257309003331	HMMPfam hit to PF01039, Carboxyl transferase domain
257309003332	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003333	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003334	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
257309003335	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
257309003336	HMMPfam hit to PF03099
257309003337	HMMPfam hit to PF02237, Biotin protein ligase C terminal domain
257309003338	2 probable transmembrane helices predicted for DIP0662 by TMHMM2.0
257309003339	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
257309003340	ATP-grasp domain; Region: ATP-grasp; pfam02222
257309003341	HMMPfam hit to PF02222, ATP-grasp domain
257309003342	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
257309003343	HMMPfam hit to PF00731, AIR carboxylase
257309003344	Uncharacterized conserved protein [Function unknown]; Region: COG1434
257309003345	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
257309003346	putative active site [active]
257309003347	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
257309003348	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
257309003349	HMMPfam hit to PF01924, Hydrogenase formation hypA family
257309003350	HupF/HypC family; Region: HupF_HypC; pfam01455
257309003351	HMMPfam hit to PF01455, HupF/HypC family
257309003352	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003353	BlastProDom hit to PD003112, PD003112
257309003354	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003355	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003356	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003357	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
257309003358	dimerization interface [polypeptide binding]; other site
257309003359	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
257309003360	ATP binding site [chemical binding]; other site
257309003361	HMMPfam hit to PF00586, AIR synthase related protein, N-terminal domain
257309003362	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal domain
257309003363	Acylphosphatase; Region: Acylphosphatase; pfam00708
257309003364	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
257309003365	HypF finger; Region: zf-HYPF; pfam07503
257309003366	HypF finger; Region: zf-HYPF; pfam07503
257309003367	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
257309003368	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
257309003369	HMMPfam hit to PF01300, SUA5/yciO/yrdC family
257309003370	HMMPfam hit to PF00708, Acylphosphatase
257309003371	ScanRegExp hit to PS00150, Acylphosphatase signature 1.
257309003372	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
257309003373	HMMPfam hit to PF01155, Hydrogenase expression/synthesis hypA family
257309003374	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
257309003375	ProfileScan hit to PS50316, Histidine-rich region.
257309003376	HMMPfam hit to PF01495, HypB/UreG nucleotide-binding domain
257309003377	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
257309003378	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
257309003379	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003380	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003381	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 Kd subunit
257309003382	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003383	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003384	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003385	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003386	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003387	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003388	FPrintScan hit to PR00614, Ni-Fe hydrogenase small subunit signature
257309003389	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
257309003390	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
257309003391	HMMPfam hit to PF00374, Nickel-dependent hydrogenase
257309003392	ScanRegExp hit to PS00508, Nickel-dependent hydrogenases large subunit signature 2.
257309003393	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
257309003394	HMMPfam hit to PF01292, Nickel-dependent hydrogenases b-type cytochrome subunit
257309003395	BlastProDom hit to PD005374, PD005374
257309003396	FPrintScan hit to PR00161, Nickel-dependent hydrogenase/B-type cytochrome signature
257309003397	4 probable transmembrane helices predicted for DIP0674 by TMHMM2.0
257309003398	FPrintScan hit to PR00161, Nickel-dependent hydrogenase/B-type cytochrome signature
257309003399	FPrintScan hit to PR00161, Nickel-dependent hydrogenase/B-type cytochrome signature
257309003400	FPrintScan hit to PR00161, Nickel-dependent hydrogenase/B-type cytochrome signature
257309003401	FPrintScan hit to PR00161, Nickel-dependent hydrogenase/B-type cytochrome signature
257309003402	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
257309003403	putative substrate-binding site; other site
257309003404	nickel binding site [ion binding]; other site
257309003405	FPrintScan hit to PR00446, Hydrogen uptake protein signature
257309003406	FPrintScan hit to PR00446, Hydrogen uptake protein signature
257309003407	HMMPfam hit to PF01750, Hydrogenase maturation protease
257309003408	FPrintScan hit to PR00446, Hydrogen uptake protein signature
257309003409	FPrintScan hit to PR00446, Hydrogen uptake protein signature
257309003410	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
257309003411	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
257309003412	HMMPfam hit to PF01155, Hydrogenase expression/synthesis hypA family
257309003413	BlastProDom hit to PD003620, PD003620
257309003414	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
257309003415	HMMPfam hit to PF00374, Nickel-dependent hydrogenase
257309003416	HupF/HypC family; Region: HupF_HypC; pfam01455
257309003417	BlastProDom hit to PD003112, PD003112; HMMPfam hit to PF01455, HupF/HypC family
257309003418	ScanRegExp hit to PS01097, Hydrogenases expression/synthesis hupF/hypC family signature.
257309003419	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003420	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003421	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003422	FPrintScan hit to PR00445, HupF/HypC hydrogenase expression/synthesis family signature
257309003423	TIGR03089 family protein; Region: TIGR03089
257309003424	HMMPfam hit to PF00501, AMP-binding enzyme
257309003425	HMMPfam hit to PF00501, AMP-binding enzyme
257309003426	Transcriptional regulator [Transcription]; Region: LytR; COG1316
257309003427	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
257309003428	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
257309003429	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
257309003430	active site
257309003431	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
257309003432	ProfileScan hit to PS50167, General Glycosyltransferase domain.
257309003433	HMMPfam hit to PF00535, Glycosyl transferase
257309003434	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
257309003435	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
257309003436	active site
257309003437	Substrate binding site; other site
257309003438	Mg++ binding site; other site
257309003439	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
257309003440	putative trimer interface [polypeptide binding]; other site
257309003441	putative CoA binding site [chemical binding]; other site
257309003442	HMMPfam hit to PF00483, Nucleotidyl transferase
257309003443	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309003444	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309003445	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309003446	Transcription factor WhiB; Region: Whib; pfam02467
257309003447	HMMPfam hit to PF02467, Transcription factor WhiB
257309003448	Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria; Region: MMP_TTHA0227_like_1; cd12954
257309003449	Protein of unknown function (DUF3499); Region: DUF3499; pfam12005
257309003450	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
257309003451	phosphomannomutase/phosphoglucomutase; Reviewed; Region: manB; PRK09542
257309003452	active site
257309003453	substrate binding site [chemical binding]; other site
257309003454	metal binding site [ion binding]; metal-binding site
257309003455	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
257309003456	ScanRegExp hit to PS00307, Legume lectins beta-chain signature.
257309003457	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309003458	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
257309003459	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309003460	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309003461	FPrintScan hit to PR00509, Phosphoglucomutase/phosphomannomutase signature
257309003462	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
257309003463	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-terminal domain
257309003464	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
257309003465	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
257309003466	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
257309003467	HMMPfam hit to PF01238, Phosphomannose isomerase type I
257309003468	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003469	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003470	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003471	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003472	ScanRegExp hit to PS00965, Phosphomannose isomerase type I signature 1.
257309003473	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003474	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003475	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003476	FPrintScan hit to PR00714, Phosphomannose isomerase type I signature
257309003477	FPrintScan hit to PR01217, Proline rich extensin signature
257309003478	ProfileScan hit to PS50099, Proline-rich region.
257309003479	FPrintScan hit to PR01217, Proline rich extensin signature
257309003480	FPrintScan hit to PR01217, Proline rich extensin signature
257309003481	FPrintScan hit to PR01217, Proline rich extensin signature
257309003482	FPrintScan hit to PR01217, Proline rich extensin signature
257309003483	1 probable transmembrane helix predicted for DIP0690 by TMHMM2.0
257309003484	Domain of unknown function (DUF4259); Region: DUF4259; pfam14078
257309003485	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
257309003486	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
257309003487	homotetramer interface [polypeptide binding]; other site
257309003488	ligand binding site [chemical binding]; other site
257309003489	catalytic site [active]
257309003490	NAD binding site [chemical binding]; other site
257309003491	HMMPfam hit to PF00670, S-adenosyl-L-homocysteine hydrolase
257309003492	ScanRegExp hit to PS00738, S-adenosyl-L-homocysteine hydrolase signature 1.
257309003493	ScanRegExp hit to PS00739, S-adenosyl-L-homocysteine hydrolase signature 2.
257309003494	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
257309003495	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
257309003496	TMP-binding site; other site
257309003497	ATP-binding site [chemical binding]; other site
257309003498	HMMPfam hit to PF02223, Thymidylate kinase
257309003499	ScanRegExp hit to PS01331, Thymidylate kinase signature.
257309003500	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
257309003501	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309003502	active site
257309003503	phosphorylation site [posttranslational modification]
257309003504	intermolecular recognition site; other site
257309003505	dimerization interface [polypeptide binding]; other site
257309003506	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
257309003507	DNA binding site [nucleotide binding]
257309003508	HMMPfam hit to PF00072, Response regulator receiver domain
257309003509	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309003510	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309003511	HMMPfam hit to PF00486, Transcriptional regulatory protein, C terminal
257309003512	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
257309003513	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
257309003514	dimerization interface [polypeptide binding]; other site
257309003515	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
257309003516	dimer interface [polypeptide binding]; other site
257309003517	phosphorylation site [posttranslational modification]
257309003518	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309003519	ATP binding site [chemical binding]; other site
257309003520	Mg2+ binding site [ion binding]; other site
257309003521	G-X-G motif; other site
257309003522	1 probable transmembrane helix predicted for DIP0695 by TMHMM2.0
257309003523	HMMPfam hit to PF00672, HAMP domain
257309003524	HMMSmart hit to SM00304, HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
257309003525	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain; HMMSmart hit to SM00388, His Kinase A (phosphoacceptor) domain
257309003526	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309003527	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309003528	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309003529	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309003530	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309003531	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309003532	lipoprotein LpqB; Provisional; Region: PRK13616
257309003533	Sporulation and spore germination; Region: Germane; pfam10646
257309003534	comF family protein; Region: comF; TIGR00201
257309003535	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309003536	active site
257309003537	ScanRegExp hit to PS00103, Purine/pyrimidine phosphoribosyl transferases signature.
257309003538	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
257309003539	30S subunit binding site; other site
257309003540	HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA ribosomal protein
257309003541	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
257309003542	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
257309003543	ATP binding site [chemical binding]; other site
257309003544	putative Mg++ binding site [ion binding]; other site
257309003545	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
257309003546	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309003547	nucleotide binding region [chemical binding]; other site
257309003548	ATP-binding site [chemical binding]; other site
257309003549	HMMPfam hit to PF01043, SecA protein, amino terminal region
257309003550	FPrintScan hit to PR00906, SecA protein signature
257309003551	FPrintScan hit to PR00906, SecA protein signature
257309003552	FPrintScan hit to PR00906, SecA protein signature
257309003553	FPrintScan hit to PR00906, SecA protein signature
257309003554	FPrintScan hit to PR00906, SecA protein signature
257309003555	FPrintScan hit to PR00906, SecA protein signature
257309003556	FPrintScan hit to PR00906, SecA protein signature
257309003557	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309003558	HMMPfam hit to PF00271, Helicase conserved C-terminal domain
257309003559	ScanRegExp hit to PS01312, Protein secA signatures.
257309003560	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
257309003561	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_2; cd06216
257309003562	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
257309003563	FAD binding pocket [chemical binding]; other site
257309003564	FAD binding motif [chemical binding]; other site
257309003565	phosphate binding motif [ion binding]; other site
257309003566	beta-alpha-beta structure motif; other site
257309003567	NAD binding pocket [chemical binding]; other site
257309003568	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
257309003569	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
257309003570	catalytic loop [active]
257309003571	iron binding site [ion binding]; other site
257309003572	HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain
257309003573	FPrintScan hit to PR00410, Phenol hydroxylase reductase signature
257309003574	FPrintScan hit to PR00371, Flavoprotein pyridine nucleotide cytochrome reductase signature
257309003575	FPrintScan hit to PR00371, Flavoprotein pyridine nucleotide cytochrome reductase signature
257309003576	FPrintScan hit to PR00406, Cytochrome B5 reductase signature
257309003577	FPrintScan hit to PR00410, Phenol hydroxylase reductase signature
257309003578	HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain
257309003579	FPrintScan hit to PR00406, Cytochrome B5 reductase signature; FPrintScan hit to PR00371, Flavoprotein pyridine nucleotide cytochrome reductase signature; FPrintScan hit to PR00410, Phenol hydroxylase reductase signature
257309003580	FPrintScan hit to PR00371, Flavoprotein pyridine nucleotide cytochrome reductase signature
257309003581	FPrintScan hit to PR00406, Cytochrome B5 reductase signature; FPrintScan hit to PR00410, Phenol hydroxylase reductase signature
257309003582	HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain
257309003583	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
257309003584	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
257309003585	putative di-iron ligands [ion binding]; other site
257309003586	Predicted GTPases [General function prediction only]; Region: COG1162
257309003587	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
257309003588	GTPase/Zn-binding domain interface [polypeptide binding]; other site
257309003589	GTP/Mg2+ binding site [chemical binding]; other site
257309003590	G4 box; other site
257309003591	G5 box; other site
257309003592	G1 box; other site
257309003593	Switch I region; other site
257309003594	G2 box; other site
257309003595	G3 box; other site
257309003596	Switch II region; other site
257309003597	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003598	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
257309003599	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
257309003600	hinge; other site
257309003601	active site
257309003602	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
257309003603	BlastProDom hit to PD001867, PD001867
257309003604	Predicted helix-turn-helix motif with score 1310 (+3.65 SD) at aa 363-384, sequence GSCTELADGLHITPSTLHGGTW
257309003605	ScanRegExp hit to PS00885, EPSP synthase signature 2.
257309003606	ScanRegExp hit to PS00104, EPSP synthase signature 1.
257309003607	Uncharacterized conserved protein [Function unknown]; Region: COG2135
257309003608	HMMPfam hit to PF02586, Uncharacterized ACR, COG2135
257309003609	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
257309003610	putative deacylase active site [active]
257309003611	RNA polymerase sigma-70 factor, TIGR02947 family; Region: SigH_actino
257309003612	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309003613	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309003614	DNA binding residues [nucleotide binding]
257309003615	HMMPfam hit to PF00776, Sigma-70 factor (ECF subfamily)
257309003616	ScanRegExp hit to PS01063, Sigma-70 factors ECF subfamily signature.
257309003617	mycothiol system anti-sigma-R factor; Region: antisig_RsrA; TIGR03988
257309003618	Domain of unknown function (DUF4288); Region: DUF4288; pfam14119
257309003619	Transcription factor WhiB; Region: Whib; pfam02467
257309003620	HMMPfam hit to PF02467, Transcription factor WhiB
257309003621	4 probable transmembrane helices predicted for DIP0715 by TMHMM2.0
257309003622	PQQ-like domain; Region: PQQ_2; pfam13360
257309003623	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
257309003624	DEAD-like helicases superfamily; Region: DEXDc; smart00487
257309003625	ATP binding site [chemical binding]; other site
257309003626	putative Mg++ binding site [ion binding]; other site
257309003627	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309003628	nucleotide binding region [chemical binding]; other site
257309003629	ATP-binding site [chemical binding]; other site
257309003630	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309003631	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309003632	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309003633	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309003634	ScanRegExp hit to PS00039, DEAD-box subfamily ATP-dependent helicases signature.
257309003635	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003636	Protein of unknown function (DUF3107); Region: DUF3107; pfam11305
257309003637	Protein of unknown function (DUF3152); Region: DUF3152; pfam11350
257309003638	1 probable transmembrane helix predicted for DIP0720 by TMHMM2.0
257309003639	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309003640	TIGR02569 family protein; Region: TIGR02569_actnb
257309003641	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
257309003642	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
257309003643	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
257309003644	ScanRegExp hit to PS00430, TonB-dependent receptor proteins signature 1.
257309003645	HMMPfam hit to PF00580, UvrD/REP helicase
257309003646	HMMPfam hit to PF00580, UvrD/REP helicase
257309003647	ScanRegExp hit to PS00136, Serine proteases, subtilase, aspartic acid active site.
257309003648	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
257309003649	Part of AAA domain; Region: AAA_19; pfam13245
257309003650	Family description; Region: UvrD_C_2; pfam13538
257309003651	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
257309003652	HMMPfam hit to PF00580, UvrD/REP helicase
257309003653	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003654	Ion channel; Region: Ion_trans_2; pfam07885
257309003655	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
257309003656	TrkA-N domain; Region: TrkA_N; pfam02254
257309003657	2 probable transmembrane helices predicted for DIP0724 by TMHMM2.0
257309003658	ProfileScan hit to PS50265, Pore region of potassium channels.
257309003659	HMMPfam hit to PF02254, KTN NAD-binding domain
257309003660	ProfileScan hit to PS50205, NAD binding site.
257309003661	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
257309003662	putative NADH binding site [chemical binding]; other site
257309003663	putative active site [active]
257309003664	nudix motif; other site
257309003665	putative metal binding site [ion binding]; other site
257309003666	HMMPfam hit to PF00293, MutT-like domain
257309003667	ScanRegExp hit to PS00893, Nudix hydrolase signature.
257309003668	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
257309003669	Part of AAA domain; Region: AAA_19; pfam13245
257309003670	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
257309003671	Family description; Region: UvrD_C_2; pfam13538
257309003672	HRDC domain; Region: HRDC; pfam00570
257309003673	HMMPfam hit to PF00580, UvrD/REP helicase
257309003674	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003675	HMMPfam hit to PF00570, HRDC domain; HMMSmart hit to SM00341, Helicase and RNase D C-terminal
257309003676	Protein of unknown function DUF45; Region: DUF45; pfam01863
257309003677	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309003678	putative hydrolase; Region: TIGR03624
257309003679	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
257309003680	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
257309003681	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF).
257309003682	hypothetical protein; Validated; Region: PRK00068
257309003683	Uncharacterized conserved protein [Function unknown]; Region: COG1615; cl09133
257309003684	7 probable transmembrane helices predicted for DIP0733 by TMHMM2.0
257309003685	Na+/glutamate symporter [Amino acid transport and metabolism]; Region: GltS; COG0786
257309003686	5 probable transmembrane helices predicted for DIP0734 by TMHMM2.0
257309003687	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cl00149
257309003688	active site
257309003689	1 probable transmembrane helix predicted for DIP0736 by TMHMM2.0
257309003690	ProfileScan hit to PS50240, Serine proteases, trypsin domain profile.
257309003691	HMMSmart hit to SM00020, Trypsin-like serine protease
257309003692	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309003693	ScanRegExp hit to PS00135, Serine proteases, trypsin family, serine active site.
257309003694	HMMPfam hit to PF00089, Trypsin
257309003695	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309003696	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309003697	Protein of unknown function (DUF418); Region: DUF418; cl12135
257309003698	9 probable transmembrane helices predicted for DIP0737 by TMHMM2.0
257309003699	oxaloacetate decarboxylase; Provisional; Region: PRK12330
257309003700	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
257309003701	active site
257309003702	catalytic residues [active]
257309003703	metal binding site [ion binding]; metal-binding site
257309003704	homodimer binding site [polypeptide binding]; other site
257309003705	HMMPfam hit to PF00682, HMGL-like
257309003706	HMMPfam hit to PF02436, Conserved carboxylase domain
257309003707	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
257309003708	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
257309003709	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
257309003710	HMMPfam hit to PF01039, Carboxyl transferase domain
257309003711	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003712	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003713	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003714	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
257309003715	carboxyltransferase (CT) interaction site; other site
257309003716	biotinylation site [posttranslational modification]; other site
257309003717	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309003718	ScanRegExp hit to PS00188, Biotin-requiring enzymes attachment site.
257309003719	ScanRegExp hit to PS00134, Serine proteases, trypsin family, histidine active site.
257309003720	Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate,  or similar substrates; Region: Bacterial_IMPase_like_1; cd01641
257309003721	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
257309003722	active site
257309003723	HMMPfam hit to PF00459, Inositol monophosphatase
257309003724	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003725	FPrintScan hit to PR00377, Inositol phosphatase/fructose-1,6-bisphosphatase signature
257309003726	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003727	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003728	ScanRegExp hit to PS00629, Inositol monophosphatase signature 1.
257309003729	FPrintScan hit to PR00377, Inositol phosphatase/fructose-1,6-bisphosphatase signature
257309003730	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003731	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
257309003732	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
257309003733	active site
257309003734	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003735	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003736	HMMPfam hit to PF00459, Inositol monophosphatase
257309003737	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003738	ScanRegExp hit to PS00629, Inositol monophosphatase signature 1.
257309003739	FPrintScan hit to PR00378, Inositol phosphatase signature
257309003740	peptide chain release factor 2; Validated; Region: prfB; PRK00578
257309003741	This domain is found in peptide chain release factors; Region: PCRF; smart00937
257309003742	RF-1 domain; Region: RF-1; pfam00472
257309003743	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain
257309003744	ScanRegExp hit to PS00745, Prokaryotic-type class I peptide chain release factors signature.
257309003745	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
257309003746	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
257309003747	12 probable transmembrane helices predicted for DIP0747 by TMHMM2.0
257309003748	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
257309003749	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309003750	Walker A/P-loop; other site
257309003751	ATP binding site [chemical binding]; other site
257309003752	Q-loop/lid; other site
257309003753	ABC transporter signature motif; other site
257309003754	Walker B; other site
257309003755	D-loop; other site
257309003756	H-loop/switch region; other site
257309003757	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309003758	HMMPfam hit to PF00005, ABC transporter
257309003759	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309003760	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003761	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309003762	ScanRegExp hit to PS00211, ABC transporters family signature.
257309003763	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
257309003764	FtsX-like permease family; Region: FtsX; pfam02687
257309003765	4 probable transmembrane helices predicted for DIP0749 by TMHMM2.0
257309003766	HMMPfam hit to PF02687, Predicted permease
257309003767	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
257309003768	SmpB-tmRNA interface; other site
257309003769	HMMPfam hit to PF01668, SmpB protein
257309003770	BlastProDom hit to PD004488, PD004488
257309003771	ScanRegExp hit to PS01317, SSRA-binding protein.
257309003772	Anomalous G+C content (50.90%) and dinucleotide signature. Possible lantibiotic biosynthesis cluster - pathogenicity island. Not present in C.glutamicum
257309003773	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
257309003774	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
257309003775	HTH-like domain; Region: HTH_21; pfam13276
257309003776	Integrase core domain; Region: rve; pfam00665
257309003777	Integrase core domain; Region: rve_2; pfam13333
257309003778	HMMPfam hit to PF00665, Integrase core domain
257309003779	type 2 lantibiotic biosynthesis protein LanM; Region: lanti_2_LanM; TIGR03897
257309003780	LanM-like proteins. LanM is a bifunctional enzyme, involved in the synthesis of class II lantibiotics. It is responsible for both the dehydration and the cyclization of the precursor-peptide during lantibiotic synthesis. The C-terminal domain shows...; Region: LanM-like; cd04792
257309003781	active site
257309003782	zinc binding site [ion binding]; other site
257309003783	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003784	sortase B anchoring signal. NPQTN - NPFTN
257309003785	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39F; cd02425
257309003786	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
257309003787	putative active site [active]
257309003788	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309003789	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
257309003790	Walker A/P-loop; other site
257309003791	ATP binding site [chemical binding]; other site
257309003792	Q-loop/lid; other site
257309003793	ABC transporter signature motif; other site
257309003794	Walker B; other site
257309003795	D-loop; other site
257309003796	H-loop/switch region; other site
257309003797	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309003798	5 probable transmembrane helices predicted for DIP0754 by TMHMM2.0
257309003799	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309003800	HMMPfam hit to PF00005, ABC transporter
257309003801	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309003802	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003803	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309003804	ScanRegExp hit to PS00211, ABC transporters family signature.
257309003805	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309003806	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
257309003807	Walker A/P-loop; other site
257309003808	ATP binding site [chemical binding]; other site
257309003809	Q-loop/lid; other site
257309003810	ABC transporter signature motif; other site
257309003811	Walker B; other site
257309003812	D-loop; other site
257309003813	H-loop/switch region; other site
257309003814	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309003815	HMMPfam hit to PF00005, ABC transporter
257309003816	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309003817	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003818	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309003819	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309003820	ScanRegExp hit to PS00211, ABC transporters family signature.
257309003821	6 probable transmembrane helices predicted for DIP0756 by TMHMM2.0
257309003822	Integrase core domain; Region: rve_3; pfam13683
257309003823	HMMPfam hit to PF00665, Integrase core domain
257309003824	Transposase, Mutator family; Region: Transposase_mut; pfam00872
257309003825	HMMPfam hit to PF00872, Transposase, Mutator family
257309003826	Pseudogene. Similar to Xanthomonas axonopodis pv. dieffenbachiae transposase TR:Q9F822 (EMBL:AF263433) (363 aa) fasta scores: E(): 2.7e-23, 33.42% id in 365 aa. C-terminal region also similar to DIP0757, IS element transposase (partial) (88 aa) fasta scores: E(): 3.9e-23, 80.000% identity in 70 aa overlap; transposase (pseudogene)
257309003827	HMMPfam hit to PF01527, Transposase
257309003828	Predicted helix-turn-helix motif with score 1667 (+4.86 SD) at aa 27-48, sequence STVAEVCRELGISEATYHRWQR
257309003829	HMMPfam hit to PF00665, Integrase core domain
257309003830	Cupin domain; Region: Cupin_2; cl17218
257309003831	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309003832	S-adenosylmethionine binding site [chemical binding]; other site
257309003833	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
257309003834	ProfileScan hit to PS50124, Generic methyl-transferase profile.
257309003835	Pseudogene. Similar to Corynebacterium jeikeium transposase B TnpB TR:Q93SI6 (EMBL:AY033500) (294 aa) fasta scores: E(): 6.7e-46, 55.29% id in 293 aa, and to Corynebacterium glutamicum IS3 related insertion element TR:Q46069 (EMBL:X69104) (298 aa) fasta scores: E(): 3.1e-45, 56.56% id in 297 aa;transposase B (pseudogene)
257309003836	HMMPfam hit to PF00665, Integrase core domain
257309003837	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
257309003838	Helix-turn-helix domain; Region: HTH_38; pfam13936
257309003839	Integrase core domain; Region: rve; pfam00665
257309003840	BlastProDom hit to PD002997, PD002997
257309003841	HMMPfam hit to PF00665, Integrase core domain
257309003842	Predicted helix-turn-helix motif with score 1647 (+4.80 SD) at aa 13-34, sequence ITTAQAALQVGVSVPVGTRWFR
257309003843	HMMPfam hit to PF00665, Integrase core domain
257309003844	HMMPfam hit to PF01527, Transposase
257309003845	Predicted helix-turn-helix motif with score 1456 (+4.15 SD) at aa 23-44, sequence LSLAAAAAELRVNRASLHQWKK
257309003846	Pseudogene. Similar to Mycobacterium tuberculosis CDC1551 aminotransferase, class I MT0881 TR:AAK45122 (EMBL:AE006976) (397 aa) fasta scores: E(): 6.1e-44, 45.9% id in 305 aa. Presents frameshifts at residues 38 and 226; aminotransferase (pseudogene)
257309003847	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309003848	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309003849	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309003850	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309003851	Protein of unknown function (DUF3239); Region: DUF3239; pfam11580
257309003852	2 probable transmembrane helices predicted for DIP0771 by TMHMM2.0
257309003853	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
257309003854	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
257309003855	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309003856	nucleotide binding region [chemical binding]; other site
257309003857	ATP-binding site [chemical binding]; other site
257309003858	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309003859	FPrintScan hit to PR00851, Xeroderma pigmentosum group B protein signature
257309003860	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309003861	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309003862	FPrintScan hit to PR00851, Xeroderma pigmentosum group B protein signature
257309003863	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
257309003864	Predicted helix-turn-helix motif with score 1123 (+3.01 SD) at aa 293-314, sequence RPVATLSRALDVEETTLYRVIA
257309003865	Transglycosylase-like domain; Region: Transglycosylas; pfam06737
257309003866	Protein of unknown function (DUF3235); Region: DUF3235; pfam11574
257309003867	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
257309003868	DNA-binding site [nucleotide binding]; DNA binding site
257309003869	RNA-binding motif; other site
257309003870	HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain
257309003871	HMMSmart hit to SM00357, Cold shock protein domain
257309003872	FPrintScan hit to PR00050, Cold shock protein signature
257309003873	FPrintScan hit to PR00050, Cold shock protein signature
257309003874	FPrintScan hit to PR00050, Cold shock protein signature
257309003875	Protein of unknown function (DUF2771); Region: DUF2771; pfam10969
257309003876	1 probable transmembrane helix predicted for DIP0777 by TMHMM2.0
257309003877	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
257309003878	Protein of unknown function (DUF3027); Region: DUF3027; pfam11228
257309003879	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
257309003880	HMMPfam hit to PF00860, Xanthine/uracil permeases family
257309003881	12 probable transmembrane helices predicted for DIP0780 by TMHMM2.0
257309003882	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
257309003883	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
257309003884	HMMPfam hit to PF00588, SpoU rRNA Methylase
257309003885	BlastProDom hit to PD001243, PD001243
257309003886	Protein of unknown function (DUF3071); Region: DUF3071; pfam11268
257309003887	Predicted helix-turn-helix motif with score 1170 (+3.17 SD) at aa 130-151, sequence ATIAEIAEENGVTESRIEPYAH
257309003888	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
257309003889	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
257309003890	catalytic residue [active]
257309003891	BlastProDom hit to PD001544, PD001544
257309003892	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
257309003893	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
257309003894	dimer interface [polypeptide binding]; other site
257309003895	active site
257309003896	citrylCoA binding site [chemical binding]; other site
257309003897	NADH binding [chemical binding]; other site
257309003898	cationic pore residues; other site
257309003899	oxalacetate/citrate binding site [chemical binding]; other site
257309003900	coenzyme A binding site [chemical binding]; other site
257309003901	catalytic triad [active]
257309003902	HMMPfam hit to PF00285, Citrate synthase
257309003903	FPrintScan hit to PR00143, Citrate synthase signature
257309003904	FPrintScan hit to PR00143, Citrate synthase signature
257309003905	FPrintScan hit to PR00143, Citrate synthase signature
257309003906	FPrintScan hit to PR00143, Citrate synthase signature
257309003907	ScanRegExp hit to PS00480, Citrate synthase signature.
257309003908	FPrintScan hit to PR00143, Citrate synthase signature
257309003909	FPrintScan hit to PR00143, Citrate synthase signature
257309003910	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
257309003911	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomerase
257309003912	ProfileScan hit to PS50059, FKBP-type peptidyl-prolyl cis-trans isomerase domain profile.
257309003913	ScanRegExp hit to PS00453, FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
257309003914	ScanRegExp hit to PS00454, FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
257309003915	Carboxyl transferase domain; Region: Carboxyl_trans; pfam01039
257309003916	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
257309003917	HMMPfam hit to PF01039, Carboxyl transferase domain
257309003918	FPrintScan hit to PR01069, Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature
257309003919	FPrintScan hit to PR01069, Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature
257309003920	FPrintScan hit to PR01069, Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature
257309003921	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003922	HMMPfam hit to PF01039, Carboxyl transferase domain
257309003923	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003924	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003925	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003926	FPrintScan hit to PR01070, Acetyl-CoA carboxylase carboxyl transferase beta subunit signature
257309003927	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
257309003928	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
257309003929	active site
257309003930	catalytic tetrad [active]
257309003931	HMMPfam hit to PF00248, Aldo/keto reductase
257309003932	FPrintScan hit to PR00069, Aldo-keto reductase signature
257309003933	ScanRegExp hit to PS00798, Aldo/keto reductase signature 1.
257309003934	FPrintScan hit to PR00069, Aldo-keto reductase signature
257309003935	FPrintScan hit to PR00069, Aldo-keto reductase signature
257309003936	FPrintScan hit to PR00069, Aldo-keto reductase signature
257309003937	FPrintScan hit to PR00069, Aldo-keto reductase signature
257309003938	ScanRegExp hit to PS00063, Aldo/keto reductase active site signature.
257309003939	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
257309003940	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
257309003941	substrate binding site [chemical binding]; other site
257309003942	oxyanion hole (OAH) forming residues; other site
257309003943	trimer interface [polypeptide binding]; other site
257309003944	HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase
257309003945	ScanRegExp hit to PS00166, Enoyl-CoA hydratase/isomerase signature.
257309003946	Protein of unknown function, DUF485; Region: DUF485; pfam04341
257309003947	2 probable transmembrane helices predicted for DIP0790 by TMHMM2.0
257309003948	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
257309003949	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
257309003950	Na binding site [ion binding]; other site
257309003951	13 probable transmembrane helices predicted for DIP0791 by TMHMM2.0
257309003952	ProfileScan hit to PS50283, Sodium:solute symporter family profile.
257309003953	HMMPfam hit to PF00474, Sodium:solute symporter family
257309003954	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309003955	Domain of unknown function (DUF1906); Region: DUF1906; pfam08924
257309003956	ProfileScan hit to PS50099, Proline-rich region.
257309003957	Potential twin-arginine recognition motif RRSFLT
257309003958	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
257309003959	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
257309003960	HMMPfam hit to PF00999, Sodium/hydrogen exchanger family
257309003961	11 probable transmembrane helices predicted for DIP0794 by TMHMM2.0
257309003962	Anomalous G+C content (59.68%) and dinucleotide signature.  phage related pathogenicity island. Not present in C.glutamicum
257309003963	Fic/DOC family; Region: Fic; cl00960
257309003964	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
257309003965	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
257309003966	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
257309003967	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
257309003968	ProfileScan hit to PS50099, Proline-rich region.
257309003969	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
257309003970	DNA methylase; Region: N6_N4_Mtase; pfam01555
257309003971	DNA methylase; Region: N6_N4_Mtase; pfam01555
257309003972	HMMPfam hit to PF01555, DNA methylase
257309003973	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309003974	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309003975	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309003976	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309003977	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309003978	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309003979	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309003980	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309003981	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309003982	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
257309003983	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
257309003984	active site
257309003985	Int/Topo IB signature motif; other site
257309003986	catalytic residues [active]
257309003987	DNA binding site [nucleotide binding]
257309003988	HMMPfam hit to PF00589, Phage integrase
257309003989	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309003990	sequence-specific DNA binding site [nucleotide binding]; other site
257309003991	salt bridge; other site
257309003992	Predicted helix-turn-helix motif with score 1325 (+3.70 SD) at aa 56-77, sequence TSPSEFCDNIGISHATLGRILR
257309003993	Precorrin-6A synthase, the cobalamin biosynthesis enzyme CobF; Region: Precorrin-6A-synthase; cd11643
257309003994	active site
257309003995	SAM binding site [chemical binding]; other site
257309003996	homodimer interface [polypeptide binding]; other site
257309003997	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309003998	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
257309003999	catalytic residues [active]
257309004000	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
257309004001	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
257309004002	folate binding site [chemical binding]; other site
257309004003	NADP+ binding site [chemical binding]; other site
257309004004	HMMPfam hit to PF00186, Dihydrofolate reductase
257309004005	FPrintScan hit to PR00070, Dihydrofolate reductase signature
257309004006	FPrintScan hit to PR00070, Dihydrofolate reductase signature
257309004007	ScanRegExp hit to PS00075, Dihydrofolate reductase signature.
257309004008	FPrintScan hit to PR00070, Dihydrofolate reductase signature
257309004009	FPrintScan hit to PR00070, Dihydrofolate reductase signature
257309004010	thymidylate synthase; Reviewed; Region: thyA; PRK01827
257309004011	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
257309004012	dimerization interface [polypeptide binding]; other site
257309004013	active site
257309004014	HMMPfam hit to PF00303, Thymidylate synthase
257309004015	BlastProDom hit to PD001180, PD001180
257309004016	FPrintScan hit to PR00108, Thymidylate synthase signature
257309004017	FPrintScan hit to PR00108, Thymidylate synthase signature
257309004018	FPrintScan hit to PR00108, Thymidylate synthase signature
257309004019	FPrintScan hit to PR00108, Thymidylate synthase signature
257309004020	FPrintScan hit to PR00108, Thymidylate synthase signature
257309004021	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
257309004022	active site
257309004023	HMMPfam hit to PF00459, Inositol monophosphatase
257309004024	FPrintScan hit to PR00378, Inositol phosphatase signature
257309004025	FPrintScan hit to PR00378, Inositol phosphatase signature
257309004026	FPrintScan hit to PR00378, Inositol phosphatase signature
257309004027	ScanRegExp hit to PS00629, Inositol monophosphatase signature 1.
257309004028	FPrintScan hit to PR00378, Inositol phosphatase signature
257309004029	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309004030	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
257309004031	ATP binding site [chemical binding]; other site
257309004032	putative Mg++ binding site [ion binding]; other site
257309004033	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309004034	nucleotide binding region [chemical binding]; other site
257309004035	ATP-binding site [chemical binding]; other site
257309004036	DEAD/H associated; Region: DEAD_assoc; pfam08494
257309004037	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309004038	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309004039	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004040	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004041	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309004042	HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309004043	HMMPfam hit to PF00271, Helicase conserved C-terminal domain
257309004044	ScanRegExp hit to PS00678, Trp-Asp (WD) repeats signature.
257309004045	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
257309004046	active site
257309004047	SUMO-1 interface [polypeptide binding]; other site
257309004048	HMMPfam hit to PF02299, G:T/U mismatch-specific DNA glycosylase
257309004049	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
257309004050	N-terminal domain of the actinomycetal Nei2 and related DNA glycosylases; Region: AcNei2_N; cd08971
257309004051	putative DNA binding site [nucleotide binding]; other site
257309004052	catalytic residue [active]
257309004053	putative H2TH interface [polypeptide binding]; other site
257309004054	putative catalytic residues [active]
257309004055	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
257309004056	BlastProDom hit to PD003680, PD003680; HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase
257309004057	Predicted permease [General function prediction only]; Region: COG2985
257309004058	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
257309004059	TrkA-C domain; Region: TrkA_C; pfam02080
257309004060	TrkA-C domain; Region: TrkA_C; pfam02080
257309004061	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
257309004062	10 probable transmembrane helices predicted for DIP0830 by TMHMM2.0
257309004063	hypothetical protein; Provisional; Region: PRK11770
257309004064	Domain of unknown function (DUF307); Region: DUF307; pfam03733
257309004065	Domain of unknown function (DUF307); Region: DUF307; pfam03733
257309004066	3 probable transmembrane helices predicted for DIP0831 by TMHMM2.0
257309004067	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
257309004068	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
257309004069	active site
257309004070	dimer interface [polypeptide binding]; other site
257309004071	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
257309004072	dimer interface [polypeptide binding]; other site
257309004073	active site
257309004074	HMMPfam hit to PF00342, Phosphoglucose isomerase
257309004075	ScanRegExp hit to PS00174, Phosphoglucose isomerase signature 2.
257309004076	FPrintScan hit to PR00662, Glucose-6-phosphate isomerase signature
257309004077	FPrintScan hit to PR00662, Glucose-6-phosphate isomerase signature
257309004078	FPrintScan hit to PR00662, Glucose-6-phosphate isomerase signature
257309004079	FPrintScan hit to PR00662, Glucose-6-phosphate isomerase signature
257309004080	FPrintScan hit to PR00662, Glucose-6-phosphate isomerase signature
257309004081	ScanRegExp hit to PS00765, Phosphoglucose isomerase signature 1.
257309004082	FPrintScan hit to PR00662, Glucose-6-phosphate isomerase signature
257309004083	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
257309004084	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
257309004085	tetramerization interface [polypeptide binding]; other site
257309004086	NAD(P) binding site [chemical binding]; other site
257309004087	catalytic residues [active]
257309004088	HMMPfam hit to PF00171, Aldehyde dehydrogenase
257309004089	ScanRegExp hit to PS00687, Aldehyde dehydrogenases glutamic acid active site.
257309004090	hypothetical protein; Provisional; Region: PRK07857
257309004091	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
257309004092	Part of AAA domain; Region: AAA_19; pfam13245
257309004093	Family description; Region: UvrD_C_2; pfam13538
257309004094	HMMPfam hit to PF00580, UvrD/REP helicase
257309004095	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004096	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
257309004097	Peptidase family M23; Region: Peptidase_M23; pfam01551
257309004098	HMMPfam hit to PF01551, Peptidase M23/M37
257309004099	1 probable transmembrane helix predicted for DIP0836 by TMHMM2.0
257309004100	9 probable transmembrane helices predicted for DIP0837 by TMHMM2.0
257309004101	ProfileScan hit to PS50313, Glutamic acid-rich region.
257309004102	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
257309004103	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
257309004104	active site
257309004105	substrate binding site [chemical binding]; other site
257309004106	cosubstrate binding site; other site
257309004107	catalytic site [active]
257309004108	HMMPfam hit to PF00551, Formyl transferase
257309004109	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
257309004110	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
257309004111	purine monophosphate binding site [chemical binding]; other site
257309004112	dimer interface [polypeptide binding]; other site
257309004113	putative catalytic residues [active]
257309004114	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
257309004115	HMMPfam hit to PF02142, MGS-like domain
257309004116	HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme
257309004117	BlastProDom hit to PD004666, PD004666
257309004118	1 probable transmembrane helix predicted for DIP0840 by TMHMM2.0
257309004119	1 probable transmembrane helix predicted for DIP0841 by TMHMM2.0
257309004120	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
257309004121	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
257309004122	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
257309004123	HTH-like domain; Region: HTH_21; pfam13276
257309004124	Integrase core domain; Region: rve; pfam00665
257309004125	Integrase core domain; Region: rve_2; pfam13333
257309004126	HMMPfam hit to PF00665, Integrase core domain
257309004127	1 probable transmembrane helix predicted for DIP0843 by TMHMM2.0
257309004128	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
257309004129	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309004130	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309004131	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309004132	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309004133	Predicted helix-turn-helix motif with score 1536 (+4.42 SD) at aa 40-61, sequence TSTHQIADAVGIRQASLYYHFP
257309004134	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309004135	Putative nucleotidyltransferase substrate binding domain; Region: DUF294_C; pfam10335
257309004136	30S ribosomal protein S18; Provisional; Region: PRK13401
257309004137	FPrintScan hit to PR00974, Ribosomal protein S18 family signature
257309004138	HMMPfam hit to PF01084, Ribosomal protein S18
257309004139	BlastProDom hit to PD002239, PD002239
257309004140	FPrintScan hit to PR00974, Ribosomal protein S18 family signature
257309004141	FPrintScan hit to PR00974, Ribosomal protein S18 family signature
257309004142	FPrintScan hit to PR00974, Ribosomal protein S18 family signature
257309004143	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
257309004144	HMMPfam hit to PF00253, Ribosomal protein S14p/S29e
257309004145	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
257309004146	HMMPfam hit to PF00471, Ribosomal protein L33
257309004147	BlastProDom hit to PD002595, PD002595
257309004148	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
257309004149	HMMPfam hit to PF00830, Ribosomal L28 family
257309004150	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
257309004151	HMMPfam hit to PF01197, Ribosomal protein L31
257309004152	FPrintScan hit to PR01249, Ribosomal protein L31 signature
257309004153	FPrintScan hit to PR01249, Ribosomal protein L31 signature
257309004154	FPrintScan hit to PR01249, Ribosomal protein L31 signature
257309004155	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
257309004156	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
257309004157	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309004158	active site
257309004159	phosphorylation site [posttranslational modification]
257309004160	intermolecular recognition site; other site
257309004161	dimerization interface [polypeptide binding]; other site
257309004162	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
257309004163	DNA binding site [nucleotide binding]
257309004164	HMMPfam hit to PF00072, Response regulator receiver domain
257309004165	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309004166	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309004167	ScanRegExp hit to PS00217, Sugar transport proteins signature 2.
257309004168	HMMPfam hit to PF00486, Transcriptional regulatory protein, C terminal
257309004169	Signal peptide predicted for DIP0855 by SignalP 2.0 HMM (Signal peptide probability 0.705) with cleavage site probability 0.338 between residues 57 and 58
257309004170	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
257309004171	dimerization interface [polypeptide binding]; other site
257309004172	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
257309004173	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
257309004174	dimer interface [polypeptide binding]; other site
257309004175	phosphorylation site [posttranslational modification]
257309004176	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309004177	ATP binding site [chemical binding]; other site
257309004178	Mg2+ binding site [ion binding]; other site
257309004179	G-X-G motif; other site
257309004180	2 probable transmembrane helices predicted for DIP0855 by TMHMM2.0
257309004181	HMMPfam hit to PF00672, HAMP domain
257309004182	HMMSmart hit to SM00304, HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
257309004183	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain; HMMSmart hit to SM00388, His Kinase A (phosphoacceptor) domain
257309004184	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309004185	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309004186	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309004187	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309004188	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309004189	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309004190	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
257309004191	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
257309004192	protein binding site [polypeptide binding]; other site
257309004193	1 probable transmembrane helix predicted for DIP0856 by TMHMM2.0
257309004194	HMMPfam hit to PF00089, Trypsin
257309004195	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309004196	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309004197	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309004198	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309004199	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309004200	ProfileScan hit to PS50106, PDZ domain profile.
257309004201	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF).
257309004202	HMMSmart hit to SM00228, Domain present in PSD-95, Dlg, and ZO-1/2.
257309004203	FPrintScan hit to PR00834, HtrA/DegQ protease signature
257309004204	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
257309004205	MPT binding site; other site
257309004206	trimer interface [polypeptide binding]; other site
257309004207	BlastProDom hit to PD002460, PD002460
257309004208	ScanRegExp hit to PS01078, Molybdenum cofactor biosynthesis proteins signature 1.
257309004209	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
257309004210	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
257309004211	HMMPfam hit to PF01741, Large-conductance mechanosensitive channel, MscL
257309004212	BlastProDom hit to PD007253, PD007253
257309004213	FPrintScan hit to PR01264, Bacterial mechano-sensitive ion channel signature
257309004214	2 probable transmembrane helices predicted for DIP0859 by TMHMM2.0
257309004215	FPrintScan hit to PR01264, Bacterial mechano-sensitive ion channel signature
257309004216	FPrintScan hit to PR01264, Bacterial mechano-sensitive ion channel signature
257309004217	1 probable transmembrane helix predicted for DIP0860 by TMHMM2.0
257309004218	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
257309004219	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
257309004220	HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase
257309004221	UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: GalU; COG1210
257309004222	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
257309004223	active site
257309004224	HMMPfam hit to PF00483, Nucleotidyl transferase
257309004225	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
257309004226	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
257309004227	dimer interface [polypeptide binding]; other site
257309004228	putative functional site; other site
257309004229	putative MPT binding site; other site
257309004230	HMMPfam hit to PF00994, Molybdenum cofactor biosynthesis protein
257309004231	BlastProDom hit to PD002460, PD002460
257309004232	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
257309004233	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
257309004234	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309004235	2 probable transmembrane helices predicted for DIP0865 by TMHMM2.0
257309004236	ProfileScan hit to PS50312, Aspartic acid-rich region.
257309004237	Predicted membrane protein [Function unknown]; Region: COG2259
257309004238	3 probable transmembrane helices predicted for DIP0866 by TMHMM2.0
257309004239	Predicted integral membrane protein [Function unknown]; Region: COG5660
257309004240	Putative zinc-finger; Region: zf-HC2; pfam13490
257309004241	4 probable transmembrane helices predicted for DIP0867 by TMHMM2.0
257309004242	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
257309004243	8 probable transmembrane helices predicted for DIP0868 by TMHMM2.0
257309004244	HMMPfam hit to PF02366, Dolichyl-phosphate-mannose-protein mannosyltransferase
257309004245	BCCT family transporter; Region: BCCT; pfam02028
257309004246	HMMPfam hit to PF02028, BCCT family transporter
257309004247	12 probable transmembrane helices predicted for DIP0869 by TMHMM2.0
257309004248	BlastProDom hit to PD010111, PD010111
257309004249	ScanRegExp hit to PS01303, BCCT family of transporters signature.
257309004250	Uncharacterized membrane protein [Function unknown]; Region: COG3949
257309004251	10 probable transmembrane helices predicted for DIP0870 by TMHMM2.0
257309004252	Predicted methyltransferases [General function prediction only]; Region: COG0313
257309004253	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
257309004254	putative SAM binding site [chemical binding]; other site
257309004255	putative homodimer interface [polypeptide binding]; other site
257309004256	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309004257	BlastProDom hit to PD007098, PD007098
257309004258	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
257309004259	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
257309004260	active site
257309004261	HIGH motif; other site
257309004262	KMSKS motif; other site
257309004263	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
257309004264	tRNA binding surface [nucleotide binding]; other site
257309004265	anticodon binding site; other site
257309004266	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V)
257309004267	FPrintScan hit to PR01041, Methionyl-tRNA synthetase signature
257309004268	FPrintScan hit to PR01041, Methionyl-tRNA synthetase signature
257309004269	FPrintScan hit to PR01041, Methionyl-tRNA synthetase signature
257309004270	FPrintScan hit to PR01041, Methionyl-tRNA synthetase signature
257309004271	FPrintScan hit to PR01041, Methionyl-tRNA synthetase signature
257309004272	FPrintScan hit to PR01041, Methionyl-tRNA synthetase signature
257309004273	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309004274	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
257309004275	active site
257309004276	HMMPfam hit to PF01026, TatD related DNase
257309004277	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3583
257309004278	Domain of unknown function (DUF348); Region: DUF348; pfam03990
257309004279	Domain of unknown function (DUF348); Region: DUF348; pfam03990
257309004280	Domain of unknown function (DUF348); Region: DUF348; pfam03990
257309004281	G5 domain; Region: G5; pfam07501
257309004282	Transglycosylase-like domain; Region: Transglycosylas; pfam06737
257309004283	1 probable transmembrane helix predicted for DIP0874 by TMHMM2.0
257309004284	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
257309004285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309004286	S-adenosylmethionine binding site [chemical binding]; other site
257309004287	HMMPfam hit to PF00398, Ribosomal RNA adenine dimethylase
257309004288	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309004289	ScanRegExp hit to PS01131, Ribosomal RNA adenine dimethylases signature.
257309004290	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK03188
257309004291	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
257309004292	ScanRegExp hit to PS00430, TonB-dependent receptor proteins signature 1.
257309004293	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
257309004294	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
257309004295	ABC transporter; Region: ABC_tran_2; pfam12848
257309004296	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
257309004297	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004298	HMMPfam hit to PF00005, ABC transporter
257309004299	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004300	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004301	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004302	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004303	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004304	HMMPfam hit to PF00005, ABC transporter
257309004305	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004306	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004307	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004308	Uncharacterized conserved protein [Function unknown]; Region: COG1359
257309004309	HMMPfam hit to PF02619, Uncharacterized ACR, YneC family COG1359
257309004310	1 probable transmembrane helix predicted for DIP0879 by TMHMM2.0
257309004311	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
257309004312	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309004313	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309004314	DNA binding residues [nucleotide binding]
257309004315	HMMPfam hit to PF00776, Sigma-70 factor (ECF subfamily)
257309004316	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
257309004317	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
257309004318	6 probable transmembrane helices predicted for DIP0883 by TMHMM2.0
257309004319	ScanRegExp hit to PS00962, Ribosomal protein S2 signature 1.
257309004320	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309004321	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
257309004322	active site
257309004323	motif I; other site
257309004324	motif II; other site
257309004325	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
257309004326	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309004327	ScanRegExp hit to PS01228, Hypothetical cof family signature 1.
257309004328	3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617
257309004329	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
257309004330	substrate binding site [chemical binding]; other site
257309004331	oxyanion hole (OAH) forming residues; other site
257309004332	trimer interface [polypeptide binding]; other site
257309004333	2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766
257309004334	HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase
257309004335	ScanRegExp hit to PS00294, Prenyl group binding site (CAAX box).
257309004336	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309004337	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309004338	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309004339	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309004340	Predicted helix-turn-helix motif with score 1652 (+4.81 SD) at aa 34-55, sequence ATVSAIAQRAGVSQRTFHNYFN
257309004341	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309004342	glyceraldehyde-3-phosphate dehydrogenase; Reviewed; Region: PRK08289
257309004343	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
257309004344	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
257309004345	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
257309004346	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309004347	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309004348	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309004349	ScanRegExp hit to PS00071, Glyceraldehyde 3-phosphate dehydrogenase active site.
257309004350	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
257309004351	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309004352	6 probable transmembrane helices predicted for DIP0893 by TMHMM2.0
257309004353	DtxR-regulated promoter/operator (IRP5: Lee et al., Infection and Immunity, (1997)65(10):4273-4280)
257309004354	Cytokine interleukin-12p40 C-terminus; Region: IL12p40_C; pfam10420
257309004355	Peptide chain release factor RF-3 [Translation, ribosomal structure and biogenesis]; Region: PrfC; COG4108
257309004356	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
257309004357	G1 box; other site
257309004358	putative GEF interaction site [polypeptide binding]; other site
257309004359	GTP/Mg2+ binding site [chemical binding]; other site
257309004360	Switch I region; other site
257309004361	G2 box; other site
257309004362	G3 box; other site
257309004363	Switch II region; other site
257309004364	G4 box; other site
257309004365	G5 box; other site
257309004366	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
257309004367	HMMPfam hit to PF03144
257309004368	HMMPfam hit to PF00009, Elongation factor Tu family
257309004369	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004370	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004371	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004372	ScanRegExp hit to PS00301, GTP-binding elongation factors signature.
257309004373	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004374	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004375	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004376	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
257309004377	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
257309004378	NAD(P) binding site [chemical binding]; other site
257309004379	active site
257309004380	HMMPfam hit to PF00106, short chain dehydrogenase
257309004381	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309004382	ScanRegExp hit to PS00061, Short-chain dehydrogenases/reductases family signature.
257309004383	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309004384	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309004385	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
257309004386	putative active site [active]
257309004387	catalytic residue [active]
257309004388	BlastProDom hit to PD005324, PD005324; HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase
257309004389	ScanRegExp hit to PS01195, Peptidyl-tRNA hydrolase signature 1.
257309004390	Predicted helix-turn-helix motif with score 1056 (+2.78 SD) at aa 29-50, sequence KSKEDLAAVLGFDPTRVGRYQK
257309004391	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309004392	active site
257309004393	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
257309004394	putative active site [active]
257309004395	catalytic residue [active]
257309004396	HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase
257309004397	BlastProDom hit to PD005324, PD005324
257309004398	ScanRegExp hit to PS01196, Peptidyl-tRNA hydrolase signature 2.
257309004399	ScanRegExp hit to PS01195, Peptidyl-tRNA hydrolase signature 1.
257309004400	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
257309004401	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
257309004402	5S rRNA interface [nucleotide binding]; other site
257309004403	CTC domain interface [polypeptide binding]; other site
257309004404	L16 interface [polypeptide binding]; other site
257309004405	HMMPfam hit to PF01386, Ribosomal L25p family
257309004406	BlastProDom hit to PD012503, PD012503
257309004407	pullulanase, type I; Region: pulA_typeI; TIGR02104
257309004408	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
257309004409	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
257309004410	Ca binding site [ion binding]; other site
257309004411	active site
257309004412	catalytic site [active]
257309004413	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309004414	HMMPfam hit to PF02922, Isoamylase N-terminal domain
257309004415	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
257309004416	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK03092
257309004417	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309004418	active site
257309004419	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309004420	ScanRegExp hit to PS00144, Asparaginase / glutaminase active site signature 1.
257309004421	ScanRegExp hit to PS00103, Purine/pyrimidine phosphoribosyl transferases signature.
257309004422	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14352
257309004423	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
257309004424	Substrate binding site; other site
257309004425	Mg++ binding site; other site
257309004426	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
257309004427	active site
257309004428	substrate binding site [chemical binding]; other site
257309004429	CoA binding site [chemical binding]; other site
257309004430	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309004431	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309004432	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309004433	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309004434	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309004435	HMMPfam hit to PF00483, Nucleotidyl transferase
257309004436	Transcriptional regulator [Transcription]; Region: LysR; COG0583
257309004437	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
257309004438	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
257309004439	putative dimerization interface [polypeptide binding]; other site
257309004440	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protein, lysR family
257309004441	Predicted helix-turn-helix motif with score 1122 (+3.01 SD) at aa 23-44, sequence GSVSAAADIVGTSQANASRSLS
257309004442	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_like_2; cd09320
257309004443	gating phenylalanine in ion channel; other site
257309004444	9 probable transmembrane helices predicted for DIP0906 by TMHMM2.0
257309004445	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
257309004446	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_2; cd12159
257309004447	putative ligand binding site [chemical binding]; other site
257309004448	putative NAD binding site [chemical binding]; other site
257309004449	catalytic site [active]
257309004450	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
257309004451	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309004452	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309004453	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309004454	Q-loop/lid; other site
257309004455	ABC transporter signature motif; other site
257309004456	Walker B; other site
257309004457	D-loop; other site
257309004458	H-loop/switch region; other site
257309004459	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309004460	6 probable transmembrane helices predicted for DIP0908 by TMHMM2.0
257309004461	HMMPfam hit to PF00005, ABC transporter
257309004462	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004463	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004464	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309004465	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309004466	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309004467	Walker A/P-loop; other site
257309004468	ATP binding site [chemical binding]; other site
257309004469	Q-loop/lid; other site
257309004470	ABC transporter signature motif; other site
257309004471	Walker B; other site
257309004472	D-loop; other site
257309004473	H-loop/switch region; other site
257309004474	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309004475	5 probable transmembrane helices predicted for DIP0909 by TMHMM2.0
257309004476	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004477	HMMPfam hit to PF00005, ABC transporter
257309004478	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004479	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004480	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004481	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309004482	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309004483	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309004484	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309004485	Predicted helix-turn-helix motif with score 1437 (+4.08 SD) at aa 31-52, sequence ASMEEIAARAGVSKPVVYEHFG
257309004486	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309004487	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
257309004488	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
257309004489	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309004490	ATP binding site [chemical binding]; other site
257309004491	putative Mg++ binding site [ion binding]; other site
257309004492	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309004493	nucleotide binding region [chemical binding]; other site
257309004494	ATP-binding site [chemical binding]; other site
257309004495	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
257309004496	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309004497	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309004498	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004499	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309004500	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309004501	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
257309004502	13 probable transmembrane helices predicted for DIP0914 by TMHMM2.0
257309004503	HMMPfam hit to PF00324, Amino acid permease
257309004504	ProfileScan hit to PS50285, Permeases for amino acids and related compounds, family I.
257309004505	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
257309004506	homodimer interface [polypeptide binding]; other site
257309004507	metal binding site [ion binding]; metal-binding site
257309004508	Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane]; Region: MltB; COG2951
257309004509	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
257309004510	enolase; Provisional; Region: eno; PRK00077
257309004511	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
257309004512	dimer interface [polypeptide binding]; other site
257309004513	metal binding site [ion binding]; metal-binding site
257309004514	substrate binding pocket [chemical binding]; other site
257309004515	HMMPfam hit to PF00113, Enol-ase
257309004516	BlastProDom hit to PD000902, PD000902
257309004517	FPrintScan hit to PR00148, Enolase signature
257309004518	FPrintScan hit to PR00148, Enolase signature
257309004519	FPrintScan hit to PR00148, Enolase signature
257309004520	FPrintScan hit to PR00148, Enolase signature
257309004521	FPrintScan hit to PR00148, Enolase signature
257309004522	ScanRegExp hit to PS00164, Enolase signature.
257309004523	FPrintScan hit to PR00148, Enolase signature
257309004524	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
257309004525	Septum formation initiator; Region: DivIC; pfam04977
257309004526	1 probable transmembrane helix predicted for DIP0918 by TMHMM2.0
257309004527	Uncharacterized conserved protein [Function unknown]; Region: COG1507
257309004528	exopolyphosphatase; Region: exo_poly_only; TIGR03706
257309004529	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
257309004530	HMMPfam hit to PF02541, Ppx/GppA phosphatase
257309004531	Helix-turn-helix domain; Region: HTH_18; pfam12833
257309004532	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
257309004533	DtxR-regulated promoter/operator region (Differs in 1 base with the promoter/operator named IRP3 in Lee et al., Infection and Immunity, (1997)65(10):4273-4280)
257309004534	ProfileScan hit to PS01124, Bacterial regulatory proteins, araC family DNA-binding domain profile.
257309004535	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix proteins, araC family
257309004536	HMMSmart hit to SM00342, helix_turn_helix, arabinose operon control protein, DNA-binding
257309004537	Predicted helix-turn-helix motif with score 1130 (+3.04 SD) at aa 133-154, sequence TPLLEFAQLHNISSRTLQRQFV
257309004538	ScanRegExp hit to PS00041, Bacterial regulatory proteins, araC family signature.
257309004539	Bax inhibitor 1 like; Region: BaxI_1; cl17691
257309004540	7 probable transmembrane helices predicted for DIP0923 by TMHMM2.0
257309004541	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
257309004542	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
257309004543	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
257309004544	HMMPfam hit to PF01272, Prokaryotic transcription elongation factor, GreA/GreB
257309004545	BlastProDom hit to PD004918, PD004918
257309004546	ScanRegExp hit to PS00830, Prokaryotic transcription elongation factors signature 2.
257309004547	ScanRegExp hit to PS00829, Prokaryotic transcription elongation factors signature 1.
257309004548	Domain of unknown function (DUF4307); Region: DUF4307; pfam14155
257309004549	1 probable transmembrane helix predicted for DIP0926 by TMHMM2.0
257309004550	mycothiol conjugate amidase Mca; Region: mycothiol_Mca; TIGR03446
257309004551	HMMPfam hit to PF02585, Uncharacterized LmbE-like protein, COG2120
257309004552	1 probable transmembrane helix predicted for DIP0928 by TMHMM2.0
257309004553	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
257309004554	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
257309004555	catalytic residue [active]
257309004556	putative FPP diphosphate  binding site; other site
257309004557	putative FPP binding hydrophobic cleft; other site
257309004558	dimer interface [polypeptide binding]; other site
257309004559	putative IPP diphosphate binding site; other site
257309004560	HMMPfam hit to PF01255,  undecaprenyl diphosphate synthase
257309004561	BlastProDom hit to PD003461, PD003461
257309004562	ScanRegExp hit to PS01066, Undecaprenyl pyrophosphate synthetase signature.
257309004563	Flavodoxin domain; Region: Flavodoxin_5; cl17428
257309004564	pantothenate kinase; Provisional; Region: PRK05439
257309004565	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
257309004566	ATP-binding site [chemical binding]; other site
257309004567	CoA-binding site [chemical binding]; other site
257309004568	Mg2+-binding site [ion binding]; other site
257309004569	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase
257309004570	FPrintScan hit to PR00988, Uridine kinase signature
257309004571	FPrintScan hit to PR00988, Uridine kinase signature
257309004572	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004573	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
257309004574	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
257309004575	dimer interface [polypeptide binding]; other site
257309004576	active site
257309004577	glycine-pyridoxal phosphate binding site [chemical binding]; other site
257309004578	folate binding site [chemical binding]; other site
257309004579	HMMPfam hit to PF00464, Serine hydroxymethyltransferase
257309004580	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
257309004581	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
257309004582	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309004583	Coenzyme A binding pocket [chemical binding]; other site
257309004584	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309004585	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
257309004586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309004587	putative substrate translocation pore; other site
257309004588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309004589	14 probable transmembrane helices predicted for DIP0936 by TMHMM2.0
257309004590	HMMPfam hit to PF00083, Sugar (and other) transporter
257309004591	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309004592	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309004593	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309004594	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309004595	ScanRegExp hit to PS00217, Sugar transport proteins signature 2.
257309004596	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309004597	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309004598	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309004599	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309004600	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309004601	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309004602	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309004603	fumarate hydratase; Reviewed; Region: fumC; PRK00485
257309004604	Class II fumarases; Region: Fumarase_classII; cd01362
257309004605	active site
257309004606	tetramer interface [polypeptide binding]; other site
257309004607	HMMPfam hit to PF00206, Lyase
257309004608	FPrintScan hit to PR00145, Delta crystallin signature; FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309004609	ScanRegExp hit to PS00163, Fumarate lyases signature.
257309004610	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309004611	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309004612	FPrintScan hit to PR00145, Delta crystallin signature
257309004613	FPrintScan hit to PR00145, Delta crystallin signature
257309004614	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309004615	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
257309004616	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
257309004617	putative active site [active]
257309004618	Protein of unknown function (DUF4245); Region: DUF4245; pfam14030
257309004619	1 probable transmembrane helix predicted for DIP0940 by TMHMM2.0
257309004620	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
257309004621	HMMPfam hit to PF02609, Exonuclease VII small subunit
257309004622	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
257309004623	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
257309004624	generic binding surface II; other site
257309004625	generic binding surface I; other site
257309004626	HMMPfam hit to PF02601, Exonuclease VII, large subunit
257309004627	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain
257309004628	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
257309004629	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
257309004630	HMMPfam hit to PF02401, LytB protein
257309004631	4 probable transmembrane helices predicted for DIP0944 by TMHMM2.0
257309004632	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
257309004633	Domain of unknown function DUF20; Region: UPF0118; pfam01594
257309004634	HMMPfam hit to PF01594, Domain of unknown function DUF20
257309004635	7 probable transmembrane helices predicted for DIP0945 by TMHMM2.0
257309004636	1 probable transmembrane helix predicted for DIP0946 by TMHMM2.0
257309004637	uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain; Region: SLC6sbd_u1; cd10334
257309004638	Na2 binding site [ion binding]; other site
257309004639	putative substrate binding site 1 [chemical binding]; other site
257309004640	Na binding site 1 [ion binding]; other site
257309004641	putative substrate binding site 2 [chemical binding]; other site
257309004642	ProfileScan hit to PS50267, Sodium:neurotransmitter symporter family profile.
257309004643	12 probable transmembrane helices predicted for DIP0947 by TMHMM2.0
257309004644	HMMPfam hit to PF00209, Sodium:neurotransmitter symporter family
257309004645	FPrintScan hit to PR00176, Sodium/chloride neurotransmitter symporter signature
257309004646	FPrintScan hit to PR00176, Sodium/chloride neurotransmitter symporter signature
257309004647	HMMPfam hit to PF00209, Sodium:neurotransmitter symporter family
257309004648	FPrintScan hit to PR00176, Sodium/chloride neurotransmitter symporter signature
257309004649	FPrintScan hit to PR00176, Sodium/chloride neurotransmitter symporter signature
257309004650	ScanRegExp hit to PS00610, Sodium:neurotransmitter symporter family signature 1.
257309004651	FPrintScan hit to PR00176, Sodium/chloride neurotransmitter symporter signature
257309004652	GTP-binding protein YchF; Reviewed; Region: PRK09601
257309004653	YchF GTPase; Region: YchF; cd01900
257309004654	G1 box; other site
257309004655	GTP/Mg2+ binding site [chemical binding]; other site
257309004656	Switch I region; other site
257309004657	G2 box; other site
257309004658	Switch II region; other site
257309004659	G3 box; other site
257309004660	G4 box; other site
257309004661	G5 box; other site
257309004662	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
257309004663	HMMPfam hit to PF01018, GTP1/OBG family
257309004664	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309004665	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004666	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309004667	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309004668	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309004669	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2354
257309004670	4 probable transmembrane helices predicted for DIP0949 by TMHMM2.0
257309004671	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
257309004672	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
257309004673	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
257309004674	HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA
257309004675	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
257309004676	5 probable transmembrane helices predicted for DIP0951 by TMHMM2.0
257309004677	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
257309004678	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
257309004679	Cl- selectivity filter; other site
257309004680	Cl- binding residues [ion binding]; other site
257309004681	pore gating glutamate residue; other site
257309004682	dimer interface [polypeptide binding]; other site
257309004683	7 probable transmembrane helices predicted for DIP0952 by TMHMM2.0
257309004684	FPrintScan hit to PR00762, Chloride channel signature
257309004685	FPrintScan hit to PR00762, Chloride channel signature
257309004686	FPrintScan hit to PR00762, Chloride channel signature
257309004687	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
257309004688	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
257309004689	Walker A/P-loop; other site
257309004690	ATP binding site [chemical binding]; other site
257309004691	Q-loop/lid; other site
257309004692	ABC transporter signature motif; other site
257309004693	Walker B; other site
257309004694	D-loop; other site
257309004695	H-loop/switch region; other site
257309004696	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
257309004697	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
257309004698	Walker A/P-loop; other site
257309004699	ATP binding site [chemical binding]; other site
257309004700	Q-loop/lid; other site
257309004701	ABC transporter signature motif; other site
257309004702	Walker B; other site
257309004703	D-loop; other site
257309004704	H-loop/switch region; other site
257309004705	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004706	HMMPfam hit to PF00005, ABC transporter
257309004707	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004708	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004709	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004710	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004711	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004712	HMMPfam hit to PF00005, ABC transporter
257309004713	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004714	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004715	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004716	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004717	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
257309004718	4 probable transmembrane helices predicted for DIP0954 by TMHMM2.0
257309004719	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cd02019
257309004720	active site
257309004721	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004722	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
257309004723	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
257309004724	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309004725	ScanRegExp hit to PS01040, Bacterial extracellular solute-binding proteins, family 5 signature.
257309004726	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
257309004727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309004728	dimer interface [polypeptide binding]; other site
257309004729	conserved gate region; other site
257309004730	ABC-ATPase subunit interface; other site
257309004731	6 probable transmembrane helices predicted for DIP0957 by TMHMM2.0
257309004732	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309004733	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
257309004734	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309004735	dimer interface [polypeptide binding]; other site
257309004736	conserved gate region; other site
257309004737	putative PBP binding loops; other site
257309004738	ABC-ATPase subunit interface; other site
257309004739	6 probable transmembrane helices predicted for DIP0958 by TMHMM2.0
257309004740	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309004741	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
257309004742	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309004743	Walker A/P-loop; other site
257309004744	ATP binding site [chemical binding]; other site
257309004745	Q-loop/lid; other site
257309004746	ABC transporter signature motif; other site
257309004747	Walker B; other site
257309004748	D-loop; other site
257309004749	H-loop/switch region; other site
257309004750	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
257309004751	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309004752	Walker A/P-loop; other site
257309004753	ATP binding site [chemical binding]; other site
257309004754	Q-loop/lid; other site
257309004755	ABC transporter signature motif; other site
257309004756	Walker B; other site
257309004757	D-loop; other site
257309004758	H-loop/switch region; other site
257309004759	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
257309004760	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004761	HMMPfam hit to PF00005, ABC transporter
257309004762	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004763	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004764	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004765	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004766	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004767	HMMPfam hit to PF00005, ABC transporter
257309004768	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004769	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004770	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004771	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004772	Low G+C content region (43.62%)
257309004773	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
257309004774	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309004775	Walker A/P-loop; other site
257309004776	ATP binding site [chemical binding]; other site
257309004777	ABC transporter signature motif; other site
257309004778	Walker B; other site
257309004779	D-loop; other site
257309004780	H-loop/switch region; other site
257309004781	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004782	HMMPfam hit to PF00005, ABC transporter
257309004783	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004784	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004785	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004786	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004787	7 probable transmembrane helices predicted for DIP0962 by TMHMM2.0
257309004788	6 probable transmembrane helices predicted for DIP0963 by TMHMM2.0
257309004789	Trypsin; Region: Trypsin; pfam00089
257309004790	active site
257309004791	substrate binding sites [chemical binding]; other site
257309004792	ProfileScan hit to PS50240, Serine proteases, trypsin domain profile.
257309004793	HMMSmart hit to SM00020, Trypsin-like serine protease
257309004794	HMMPfam hit to PF00089, Trypsin
257309004795	FPrintScan hit to PR00839, V8 serine protease signature
257309004796	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309004797	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309004798	FPrintScan hit to PR00839, V8 serine protease signature
257309004799	FPrintScan hit to PR00722, Chymotrypsin serine protease (S1) signature
257309004800	1 probable transmembrane helix predicted for DIP0964 by TMHMM2.0
257309004801	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
257309004802	ArsC family; Region: ArsC; pfam03960
257309004803	catalytic residues [active]
257309004804	Protein of unknown function (DUF402); Region: DUF402; cl00979
257309004805	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
257309004806	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
257309004807	G1 box; other site
257309004808	GTP/Mg2+ binding site [chemical binding]; other site
257309004809	G2 box; other site
257309004810	Switch I region; other site
257309004811	G3 box; other site
257309004812	Switch II region; other site
257309004813	G4 box; other site
257309004814	G5 box; other site
257309004815	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
257309004816	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
257309004817	HMMPfam hit to PF00009, Elongation factor Tu family
257309004818	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004819	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004820	ScanRegExp hit to PS00301, GTP-binding elongation factors signature.
257309004821	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004822	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004823	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004824	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309004825	HMMPfam hit to PF03144
257309004826	The substrate-binding domain of mycobacterial lipoprotein Lpqw contains type 2 periplasmic binding fold; Region: PBP2_Lpqw; cd08501
257309004827	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
257309004828	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
257309004829	ScanRegExp hit to PS00228, Tubulin-beta mRNA autoregulation signal.
257309004830	HMMPfam hit to PF02585, Uncharacterized LmbE-like protein, COG2120
257309004831	4 probable transmembrane helices predicted for DIP0972 by TMHMM2.0
257309004832	Ferredoxin [Energy production and conversion]; Region: COG1146
257309004833	4Fe-4S binding domain; Region: Fer4; pfam00037
257309004834	FPrintScan hit to PR00354, 7Fe ferredoxin signature
257309004835	FPrintScan hit to PR00354, 7Fe ferredoxin signature
257309004836	HMMPfam hit to PF00037, 4Fe-4S binding domain
257309004837	FPrintScan hit to PR00354, 7Fe ferredoxin signature
257309004838	ScanRegExp hit to PS00198, 4Fe-4S ferredoxins, iron-sulfur binding region signature.
257309004839	N-succinyldiaminopimelate aminotransferase; Reviewed; Region: PRK07865
257309004840	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309004841	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309004842	homodimer interface [polypeptide binding]; other site
257309004843	catalytic residue [active]
257309004844	HMMPfam hit to PF00155, Aminotransferase class I and II
257309004845	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
257309004846	active site
257309004847	BlastProDom hit to PD001819, PD001819
257309004848	HMMPfam hit to PF00849, RNA pseudouridylate synthase
257309004849	ScanRegExp hit to PS01129, Rlu family of pseudouridine synthase signature.
257309004850	Predicted membrane protein [Function unknown]; Region: COG2246
257309004851	GtrA-like protein; Region: GtrA; pfam04138
257309004852	4 probable transmembrane helices predicted for DIP0976 by TMHMM2.0
257309004853	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309004854	active site
257309004855	HMMSmart hit to SM00507, HNH nucleases
257309004856	Possible duplication region
257309004857	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
257309004858	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
257309004859	HMMPfam hit to PF00324, Amino acid permease
257309004860	12 probable transmembrane helices predicted for DIP0978 by TMHMM2.0
257309004861	ProfileScan hit to PS50286, Permeases for amino acids and related compounds, family II.
257309004862	ProfileScan hit to PS50285, Permeases for amino acids and related compounds, family I.
257309004863	ScanRegExp hit to PS00218, Amino acid permeases signature.
257309004864	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Region: DapD_actino; TIGR03535
257309004865	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
257309004866	putative trimer interface [polypeptide binding]; other site
257309004867	putative CoA binding site [chemical binding]; other site
257309004868	gamma-aminobutyrate permease; Region: GABAperm; TIGR01773
257309004869	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
257309004870	HMMPfam hit to PF00324, Amino acid permease
257309004871	12 probable transmembrane helices predicted for DIP0980 by TMHMM2.0
257309004872	ProfileScan hit to PS50286, Permeases for amino acids and related compounds, family II.
257309004873	ProfileScan hit to PS50285, Permeases for amino acids and related compounds, family I.
257309004874	ScanRegExp hit to PS00213, Lipocalin signature.
257309004875	ScanRegExp hit to PS00218, Amino acid permeases signature.
257309004876	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Region: DapD_gpp; TIGR03536
257309004877	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
257309004878	putative trimer interface [polypeptide binding]; other site
257309004879	putative CoA binding site [chemical binding]; other site
257309004880	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13007
257309004881	M20 Peptidase actinobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_actinobac; cd05647
257309004882	metal binding site [ion binding]; metal-binding site
257309004883	putative dimer interface [polypeptide binding]; other site
257309004884	HMMPfam hit to PF01546, Peptidase M20/M25/M40
257309004885	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
257309004886	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
257309004887	dihydropteroate synthase; Region: DHPS; TIGR01496
257309004888	substrate binding pocket [chemical binding]; other site
257309004889	dimer interface [polypeptide binding]; other site
257309004890	inhibitor binding site; inhibition site
257309004891	ScanRegExp hit to PS00792, Dihydropteroate synthase signature 1.
257309004892	HMMPfam hit to PF00809, Dihydropteroate synthase
257309004893	ScanRegExp hit to PS00793, Dihydropteroate synthase signature 2.
257309004894	putative glucosyl-3-phosphoglycerate synthase; Provisional; Region: PRK13915
257309004895	ProfileScan hit to PS50167, General Glycosyltransferase domain.
257309004896	HMMPfam hit to PF00535, Glycosyl transferase
257309004897	1 probable transmembrane helix predicted for DIP0986 by TMHMM2.0
257309004898	Protein of unknown function (DUF3117); Region: DUF3117; pfam11314
257309004899	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
257309004900	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309004901	S-adenosylmethionine binding site [chemical binding]; other site
257309004902	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309004903	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
257309004904	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
257309004905	active site
257309004906	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
257309004907	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
257309004908	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
257309004909	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
257309004910	HMMPfam hit to PF00534, Glycosyl transferases group 1
257309004911	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00844
257309004912	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
257309004913	ligand binding site; other site
257309004914	oligomer interface; other site
257309004915	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
257309004916	dimer interface [polypeptide binding]; other site
257309004917	N-terminal domain interface [polypeptide binding]; other site
257309004918	sulfate 1 binding site; other site
257309004919	HMMPfam hit to PF00483, Nucleotidyl transferase
257309004920	ScanRegExp hit to PS00808, ADP-glucose pyrophosphorylase signature 1.
257309004921	ScanRegExp hit to PS00809, ADP-glucose pyrophosphorylase signature 2.
257309004922	ScanRegExp hit to PS00810, ADP-glucose pyrophosphorylase signature 3.
257309004923	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
257309004924	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
257309004925	RNA polymerase sigma factor SigE; Reviewed; Region: PRK09647
257309004926	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309004927	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309004928	DNA binding residues [nucleotide binding]
257309004929	HMMPfam hit to PF00776, Sigma-70 factor (ECF subfamily)
257309004930	ScanRegExp hit to PS00225, Crystallins beta and gamma 'Greek key' motif signature.
257309004931	Predicted helix-turn-helix motif with score 1360 (+3.82 SD) at aa 190-211, sequence MSYDEIADTLGVKMGTVRSRIH
257309004932	Putative zinc-finger; Region: zf-HC2; pfam13490
257309004933	sec-independent translocase; Provisional; Region: tatB; PRK00182
257309004934	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
257309004935	FPrintScan hit to PR01506, Bacterial sec-independent translocation TatB protein signature
257309004936	FPrintScan hit to PR01506, Bacterial sec-independent translocation TatB protein signature
257309004937	FPrintScan hit to PR01506, Bacterial sec-independent translocation TatB protein signature
257309004938	Domain of unknown function DUF59; Region: DUF59; pfam01883
257309004939	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
257309004940	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
257309004941	HMMPfam hit to PF00142, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family
257309004942	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004943	BlastProDom hit to PD005595, PD005595
257309004944	HMMPfam hit to PF01883, Domain of unknown function DUF59
257309004945	Predicted membrane protein [Function unknown]; Region: COG4420
257309004946	2 probable transmembrane helices predicted for DIP0998 by TMHMM2.0
257309004947	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
257309004948	MgtE intracellular N domain; Region: MgtE_N; smart00924
257309004949	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
257309004950	2 probable transmembrane helices predicted for DIP.1000 by TMHMM2.0
257309004951	alpha-ketoglutarate decarboxylase; Reviewed; Region: kgd; PRK12270
257309004952	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
257309004953	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
257309004954	TPP-binding site [chemical binding]; other site
257309004955	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
257309004956	HMMPfam hit to PF02779, Transketolase, pyridine binding domain
257309004957	HMMPfam hit to PF00676, Dehydrogenase E1 component
257309004958	HMMPfam hit to PF00198, 2-oxo acid dehydrogenases acyltransferase (catalytic domain)
257309004959	BlastProDom hit to PD001115, PD001115
257309004960	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309004961	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309004962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309004963	Walker A/P-loop; other site
257309004964	ATP binding site [chemical binding]; other site
257309004965	Q-loop/lid; other site
257309004966	ABC transporter signature motif; other site
257309004967	Walker B; other site
257309004968	D-loop; other site
257309004969	H-loop/switch region; other site
257309004970	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309004971	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309004972	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309004973	Walker A/P-loop; other site
257309004974	ATP binding site [chemical binding]; other site
257309004975	Q-loop/lid; other site
257309004976	ABC transporter signature motif; other site
257309004977	Walker B; other site
257309004978	D-loop; other site
257309004979	H-loop/switch region; other site
257309004980	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004981	HMMPfam hit to PF00005, ABC transporter
257309004982	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004983	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004984	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004985	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309004986	11 probable transmembrane helices predicted for DIP1003 by TMHMM2.0
257309004987	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309004988	HMMPfam hit to PF00005, ABC transporter
257309004989	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309004990	ScanRegExp hit to PS00211, ABC transporters family signature.
257309004991	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309004992	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309004993	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309004994	Transposase; Region: DDE_Tnp_ISL3; pfam01610
257309004995	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
257309004996	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
257309004997	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
257309004998	shikimate binding site; other site
257309004999	NAD(P) binding site [chemical binding]; other site
257309005000	HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase
257309005001	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
257309005002	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
257309005003	substrate binding pocket [chemical binding]; other site
257309005004	catalytic triad [active]
257309005005	HMMPfam hit to PF00135, Carboxylesterase
257309005006	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309005007	ScanRegExp hit to PS00122, Carboxylesterases type-B serine active site.
257309005008	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
257309005009	ProfileScan hit to PS50312, Aspartic acid-rich region.
257309005010	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
257309005011	active site
257309005012	catalytic residues [active]
257309005013	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u2; cd11478
257309005014	putative transporter; Provisional; Region: PRK10484
257309005015	Na binding site [ion binding]; other site
257309005016	14 probable transmembrane helices predicted for DIP1012 by TMHMM2.0
257309005017	ProfileScan hit to PS50283, Sodium:solute symporter family profile.
257309005018	HMMPfam hit to PF00474, Sodium:solute symporter family
257309005019	2 probable transmembrane helices predicted for DIP1013 by TMHMM2.0
257309005020	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
257309005021	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
257309005022	nucleotide binding site/active site [active]
257309005023	HIT family signature motif; other site
257309005024	catalytic residue [active]
257309005025	BlastProDom hit to PD005051, PD005051
257309005026	HMMPfam hit to PF01087, Galactose-1-phosphate uridyl transferase, N-terminal domain
257309005027	ScanRegExp hit to PS00117, Galactose-1-phosphate uridyl transferase 1 active site signature.
257309005028	HMMPfam hit to PF02744, Galactose-1-phosphate uridyl transferase, C-terminal domain
257309005029	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
257309005030	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
257309005031	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
257309005032	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
257309005033	FPrintScan hit to PR00959, Mevalonate kinase signature
257309005034	FPrintScan hit to PR00960, LmbP protein signature
257309005035	FPrintScan hit to PR00473, Galactokinase signature
257309005036	ScanRegExp hit to PS00106, Galactokinase signature.
257309005037	FPrintScan hit to PR00473, Galactokinase signature
257309005038	HMMPfam hit to PF00288, GHMP kinases  ATP-binding protein
257309005039	FPrintScan hit to PR00473, Galactokinase signature
257309005040	FPrintScan hit to PR00959, Mevalonate kinase signature
257309005041	FPrintScan hit to PR00960, LmbP protein signature
257309005042	ScanRegExp hit to PS00627, GHMP kinases ATP-binding domain.
257309005043	FPrintScan hit to PR00959, Mevalonate kinase signature
257309005044	FPrintScan hit to PR00473, Galactokinase signature
257309005045	FPrintScan hit to PR00959, Mevalonate kinase signature
257309005046	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b1; cd09203
257309005047	PLD-like domain; Region: PLDc_2; pfam13091
257309005048	putative homodimer interface [polypeptide binding]; other site
257309005049	putative active site [active]
257309005050	catalytic site [active]
257309005051	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
257309005052	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309005053	putative Mg++ binding site [ion binding]; other site
257309005054	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309005055	nucleotide binding region [chemical binding]; other site
257309005056	ATP-binding site [chemical binding]; other site
257309005057	Domain of unknown function (DUF3427); Region: DUF3427; pfam11907
257309005058	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309005059	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309005060	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309005061	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309005062	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005063	ProfileScan hit to PS50035, Phospholipase D/Transphosphatidylase (also polyphosphate kinases, secreted nucleases)
257309005064	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
257309005065	active site
257309005066	8-oxo-dGMP binding site [chemical binding]; other site
257309005067	nudix motif; other site
257309005068	metal binding site [ion binding]; metal-binding site
257309005069	HMMPfam hit to PF00293, MutT-like domain
257309005070	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309005071	ScanRegExp hit to PS00893, Nudix hydrolase signature.
257309005072	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309005073	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
257309005074	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
257309005075	ATP binding site [chemical binding]; other site
257309005076	Mg++ binding site [ion binding]; other site
257309005077	motif III; other site
257309005078	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309005079	nucleotide binding region [chemical binding]; other site
257309005080	ATP-binding site [chemical binding]; other site
257309005081	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
257309005082	putative RNA binding site [nucleotide binding]; other site
257309005083	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309005084	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309005085	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005086	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309005087	ScanRegExp hit to PS00039, DEAD-box subfamily ATP-dependent helicases signature.
257309005088	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309005089	ProfileScan hit to PS50323, Arginine-rich region.
257309005090	ProfileScan hit to PS50315, Glycine-rich region.
257309005091	4 probable transmembrane helices predicted for DIP1020 by TMHMM2.0
257309005092	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
257309005093	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
257309005094	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
257309005095	Na binding site [ion binding]; other site
257309005096	12 probable transmembrane helices predicted for DIP1022 by TMHMM2.0
257309005097	ProfileScan hit to PS50283, Sodium:solute symporter family profile.
257309005098	ScanRegExp hit to PS00457, Sodium:solute symporter family signature 2.
257309005099	HMMPfam hit to PF00474, Sodium:solute symporter family
257309005100	SNF2 Helicase protein; Region: DUF3670; pfam12419
257309005101	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
257309005102	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309005103	ATP binding site [chemical binding]; other site
257309005104	putative Mg++ binding site [ion binding]; other site
257309005105	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309005106	nucleotide binding region [chemical binding]; other site
257309005107	ATP-binding site [chemical binding]; other site
257309005108	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309005109	HMMPfam hit to PF00176, SNF2 and others N-terminal domain
257309005110	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309005111	Uncharacterized conserved protein [Function unknown]; Region: COG4279
257309005112	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
257309005113	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
257309005114	active site
257309005115	metal binding site [ion binding]; metal-binding site
257309005116	DNA binding site [nucleotide binding]
257309005117	HMMPfam hit to PF02549, DNA repair exonuclease
257309005118	ProfileScan hit to PS50185, Metallo-phosphoesterase motif.
257309005119	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
257309005120	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309005121	Walker A/P-loop; other site
257309005122	ATP binding site [chemical binding]; other site
257309005123	Q-loop/lid; other site
257309005124	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005125	Uncharacterized conserved protein [Function unknown]; Region: COG2353
257309005126	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
257309005127	MarR family; Region: MarR_2; pfam12802
257309005128	HMMSmart hit to SM00347, helix_turn_helix multiple antibiotic resistance protein, DNA-binding
257309005129	HMMPfam hit to PF01047, MarR family
257309005130	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
257309005131	1 probable transmembrane helix predicted for DIP1029 by TMHMM2.0
257309005132	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
257309005133	HMMPfam hit to PF02589, Uncharacterized ACR, YkgG family COG1556
257309005134	ScanRegExp hit to PS00215, Mitochondrial energy transfer proteins signature.
257309005135	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
257309005136	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
257309005137	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
257309005138	ScanRegExp hit to PS00198, 4Fe-4S ferredoxins, iron-sulfur binding region signature.
257309005139	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
257309005140	Cysteine-rich domain; Region: CCG; pfam02754
257309005141	Cysteine-rich domain; Region: CCG; pfam02754
257309005142	HMMPfam hit to PF02754, Domain of unknown function (DUF224)
257309005143	HMMPfam hit to PF02754, Domain of unknown function (DUF224)
257309005144	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
257309005145	L-lactate permease; Region: Lactate_perm; cl00701
257309005146	13 probable transmembrane helices predicted for DIP1033 by TMHMM2.0
257309005147	HMMPfam hit to PF02652, L-lactate permease
257309005148	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
257309005149	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
257309005150	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
257309005151	active site
257309005152	HIGH motif; other site
257309005153	KMSK motif region; other site
257309005154	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
257309005155	tRNA binding surface [nucleotide binding]; other site
257309005156	anticodon binding site; other site
257309005157	HMMPfam hit to PF00750, tRNA synthetases class I (R)
257309005158	FPrintScan hit to PR01038, Arginyl-tRNA synthetase signature
257309005159	ScanRegExp hit to PS00178, Aminoacyl-transfer RNA synthetases class-I signature.
257309005160	FPrintScan hit to PR01038, Arginyl-tRNA synthetase signature
257309005161	FPrintScan hit to PR01038, Arginyl-tRNA synthetase signature
257309005162	FPrintScan hit to PR01038, Arginyl-tRNA synthetase signature
257309005163	diaminopimelate decarboxylase; Region: lysA; TIGR01048
257309005164	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
257309005165	active site
257309005166	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
257309005167	substrate binding site [chemical binding]; other site
257309005168	catalytic residues [active]
257309005169	dimer interface [polypeptide binding]; other site
257309005170	HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, pyridoxal binding domain
257309005171	FPrintScan hit to PR01179, Ornithine/diaminopimelate/arginine (ODA) decarboxylase signature; ScanRegExp hit to PS00878, Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.
257309005172	FPrintScan hit to PR01181, Diaminopimelate decarboxylase signature
257309005173	FPrintScan hit to PR01179, Ornithine/diaminopimelate/arginine (ODA) decarboxylase signature
257309005174	FPrintScan hit to PR01181, Diaminopimelate decarboxylase signature
257309005175	FPrintScan hit to PR01179, Ornithine/diaminopimelate/arginine (ODA) decarboxylase signature
257309005176	ScanRegExp hit to PS00879, Orn/DAP/Arg decarboxylases family 2 signature 2.
257309005177	FPrintScan hit to PR01179, Ornithine/diaminopimelate/arginine (ODA) decarboxylase signature
257309005178	HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-terminal sheet domain
257309005179	FPrintScan hit to PR01181, Diaminopimelate decarboxylase signature
257309005180	FPrintScan hit to PR01179, Ornithine/diaminopimelate/arginine (ODA) decarboxylase signature
257309005181	FPrintScan hit to PR01181, Diaminopimelate decarboxylase signature
257309005182	homoserine dehydrogenase; Provisional; Region: PRK06349
257309005183	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
257309005184	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
257309005185	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
257309005186	HMMPfam hit to PF00742, Homoserine dehydrogenase
257309005187	ScanRegExp hit to PS01042, Homoserine dehydrogenase signature.
257309005188	HMMPfam hit to PF01842, ACT domain
257309005189	homoserine kinase; Provisional; Region: PRK01212
257309005190	FPrintScan hit to PR00958, Homoserine kinase signature
257309005191	HMMPfam hit to PF00288, GHMP kinases  ATP-binding protein
257309005192	ScanRegExp hit to PS00627, GHMP kinases ATP-binding domain.
257309005193	FPrintScan hit to PR00958, Homoserine kinase signature
257309005194	FPrintScan hit to PR00958, Homoserine kinase signature
257309005195	FPrintScan hit to PR00958, Homoserine kinase signature
257309005196	FPrintScan hit to PR00958, Homoserine kinase signature
257309005197	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK05620
257309005198	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309005199	acyl-activating enzyme (AAE) consensus motif; other site
257309005200	AMP binding site [chemical binding]; other site
257309005201	active site
257309005202	CoA binding site [chemical binding]; other site
257309005203	HMMPfam hit to PF00501, AMP-binding enzyme
257309005204	HMMPfam hit to PF00501, AMP-binding enzyme
257309005205	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309005206	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
257309005207	transcription termination factor Rho; Provisional; Region: PRK12608
257309005208	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
257309005209	RNA binding site [nucleotide binding]; other site
257309005210	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
257309005211	multimer interface [polypeptide binding]; other site
257309005212	Walker A motif; other site
257309005213	ATP binding site [chemical binding]; other site
257309005214	Walker B motif; other site
257309005215	ProfileScan hit to PS50323, Arginine-rich region.
257309005216	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleotide-binding domain
257309005217	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309005218	peptide chain release factor 1; Validated; Region: prfA; PRK00591
257309005219	This domain is found in peptide chain release factors; Region: PCRF; smart00937
257309005220	RF-1 domain; Region: RF-1; pfam00472
257309005221	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain
257309005222	ScanRegExp hit to PS00745, Prokaryotic-type class I peptide chain release factors signature.
257309005223	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
257309005224	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309005225	S-adenosylmethionine binding site [chemical binding]; other site
257309005226	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309005227	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309005228	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
257309005229	HMMPfam hit to PF01300, SUA5/yciO/yrdC family
257309005230	ScanRegExp hit to PS01147, SUA5/yciO/yrdC family signature.
257309005231	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
257309005232	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
257309005233	Mg++ binding site [ion binding]; other site
257309005234	putative catalytic motif [active]
257309005235	substrate binding site [chemical binding]; other site
257309005236	11 probable transmembrane helices predicted for DIP1044 by TMHMM2.0
257309005237	HMMPfam hit to PF00953, Glycosyl transferase
257309005238	4 probable transmembrane helices predicted for DIP1045 by TMHMM2.0
257309005239	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
257309005240	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
257309005241	6 probable transmembrane helices predicted for DIP1046 by TMHMM2.0
257309005242	HMMPfam hit to PF00119, ATP synthase A chain
257309005243	FPrintScan hit to PR00123, ATP synthase A subunit signature
257309005244	FPrintScan hit to PR00123, ATP synthase A subunit signature
257309005245	ScanRegExp hit to PS00449, ATP synthase a subunit signature.
257309005246	FPrintScan hit to PR00123, ATP synthase A subunit signature
257309005247	F0F1 ATP synthase subunit C; Validated; Region: PRK07874
257309005248	2 probable transmembrane helices predicted for DIP1047 by TMHMM2.0
257309005249	HMMPfam hit to PF00137, ATP synthase subunit C
257309005250	FPrintScan hit to PR00124, ATP synthase C subunit signature
257309005251	FPrintScan hit to PR00124, ATP synthase C subunit signature
257309005252	ScanRegExp hit to PS00605, ATP synthase c subunit signature.
257309005253	FPrintScan hit to PR00124, ATP synthase C subunit signature
257309005254	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
257309005255	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
257309005256	1 probable transmembrane helix predicted for DIP1048 by TMHMM2.0
257309005257	HMMPfam hit to PF00430, ATP synthase B/B' CF(0)
257309005258	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13430
257309005259	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
257309005260	HMMPfam hit to PF00213, ATP synthase delta (OSCP) subunit
257309005261	FPrintScan hit to PR00125, ATP synthase delta subunit signature
257309005262	ScanRegExp hit to PS00389, ATP synthase delta (OSCP) subunit signature.
257309005263	FPrintScan hit to PR00125, ATP synthase delta subunit signature
257309005264	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
257309005265	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
257309005266	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
257309005267	beta subunit interaction interface [polypeptide binding]; other site
257309005268	Walker A motif; other site
257309005269	ATP binding site [chemical binding]; other site
257309005270	Walker B motif; other site
257309005271	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
257309005272	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-barrel domain
257309005273	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleotide-binding domain
257309005274	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005275	ScanRegExp hit to PS00152, ATP synthase alpha and beta subunits signature.
257309005276	BlastProDom hit to PD001099, PD001099
257309005277	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C terminal domain
257309005278	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
257309005279	core domain interface [polypeptide binding]; other site
257309005280	delta subunit interface [polypeptide binding]; other site
257309005281	epsilon subunit interface [polypeptide binding]; other site
257309005282	HMMPfam hit to PF00231, ATP synthase
257309005283	FPrintScan hit to PR00126, ATP synthase gamma subunit signature
257309005284	FPrintScan hit to PR00126, ATP synthase gamma subunit signature
257309005285	FPrintScan hit to PR00126, ATP synthase gamma subunit signature
257309005286	FPrintScan hit to PR00126, ATP synthase gamma subunit signature
257309005287	ScanRegExp hit to PS00153, ATP synthase gamma subunit signature.
257309005288	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
257309005289	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
257309005290	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
257309005291	alpha subunit interaction interface [polypeptide binding]; other site
257309005292	Walker A motif; other site
257309005293	ATP binding site [chemical binding]; other site
257309005294	Walker B motif; other site
257309005295	inhibitor binding site; inhibition site
257309005296	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
257309005297	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-barrel domain
257309005298	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleotide-binding domain
257309005299	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309005300	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005301	ScanRegExp hit to PS00152, ATP synthase alpha and beta subunits signature.
257309005302	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C terminal domain
257309005303	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
257309005304	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
257309005305	gamma subunit interface [polypeptide binding]; other site
257309005306	epsilon subunit interface [polypeptide binding]; other site
257309005307	LBP interface [polypeptide binding]; other site
257309005308	HMMPfam hit to PF02823, ATP synthase, Delta/Epsilon chain, beta-sandwich domain
257309005309	BlastProDom hit to PD000944, PD000944
257309005310	Protein of unknown function (DUF2550); Region: DUF2550; pfam10739
257309005311	Predicted nuclease of the RecB family [DNA replication, recombination, and repair]; Region: COG1637
257309005312	hypothetical protein; Provisional; Region: PRK03298
257309005313	HMMPfam hit to PF01939, Protein of unknown function DUF91
257309005314	BlastProDom hit to PD013521, PD013521
257309005315	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
257309005316	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
257309005317	dimer interface [polypeptide binding]; other site
257309005318	substrate binding site [chemical binding]; other site
257309005319	metal binding site [ion binding]; metal-binding site
257309005320	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
257309005321	Domain of unknown function DUF77; Region: DUF77; pfam01910
257309005322	HMMPfam hit to PF01910, Protein of unknown function DUF77
257309005323	iron uptake system. Low GC content (58.02%)
257309005324	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
257309005325	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
257309005326	Walker A/P-loop; other site
257309005327	ATP binding site [chemical binding]; other site
257309005328	Q-loop/lid; other site
257309005329	ABC transporter signature motif; other site
257309005330	Walker B; other site
257309005331	D-loop; other site
257309005332	H-loop/switch region; other site
257309005333	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309005334	HMMPfam hit to PF00005, ABC transporter
257309005335	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309005336	ScanRegExp hit to PS00211, ABC transporters family signature.
257309005337	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309005338	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005339	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
257309005340	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309005341	ABC-ATPase subunit  interface; other site
257309005342	dimer interface [polypeptide binding]; other site
257309005343	putative PBP binding regions; other site
257309005344	HMMPfam hit to PF01032, FecCD transport family
257309005345	9 probable transmembrane helices predicted for DIP1060 by TMHMM2.0
257309005346	BlastProDom hit to PD001557, PD001557
257309005347	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
257309005348	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309005349	ABC-ATPase subunit  interface; other site
257309005350	dimer interface [polypeptide binding]; other site
257309005351	putative PBP binding regions; other site
257309005352	BlastProDom hit to PD001557, PD001557
257309005353	HMMPfam hit to PF01032, FecCD transport family
257309005354	9 probable transmembrane helices predicted for DIP1061 by TMHMM2.0
257309005355	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
257309005356	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
257309005357	siderophore binding site; other site
257309005358	HMMPfam hit to PF01497, Periplasmic binding protein
257309005359	TIGR02611 family protein; Region: TIGR02611
257309005360	3 probable transmembrane helices predicted for DIP1063 by TMHMM2.0
257309005361	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
257309005362	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
257309005363	ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).
257309005364	ProfileScan hit to PS50005, TPR repeat.
257309005365	glycogen branching enzyme; Provisional; Region: PRK05402
257309005366	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
257309005367	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
257309005368	active site
257309005369	catalytic site [active]
257309005370	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
257309005371	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309005372	HMMPfam hit to PF02922, Isoamylase N-terminal domain
257309005373	Domain of unknown function (DUF3416); Region: DUF3416; pfam11896
257309005374	Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344
257309005375	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
257309005376	active site
257309005377	homodimer interface [polypeptide binding]; other site
257309005378	catalytic site [active]
257309005379	acceptor binding site [chemical binding]; other site
257309005380	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309005381	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]; Region: ModF; COG1119
257309005382	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309005383	Walker A/P-loop; other site
257309005384	ATP binding site [chemical binding]; other site
257309005385	Q-loop/lid; other site
257309005386	ABC transporter signature motif; other site
257309005387	Walker B; other site
257309005388	D-loop; other site
257309005389	H-loop/switch region; other site
257309005390	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309005391	HMMPfam hit to PF00005, ABC transporter
257309005392	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309005393	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005394	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309005395	HMMPfam hit to PF00293, MutT-like domain
257309005396	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
257309005397	Ligand binding site [chemical binding]; other site
257309005398	Electron transfer flavoprotein domain; Region: ETF; pfam01012
257309005399	BlastProDom hit to PD003528, PD003528
257309005400	HMMPfam hit to PF01012, Electron transfer flavoprotein beta subunit
257309005401	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
257309005402	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
257309005403	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
257309005404	HMMPfam hit to PF00766, Electron transfer flavoprotein alpha subunit
257309005405	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309005406	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
257309005407	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
257309005408	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
257309005409	catalytic residue [active]
257309005410	HMMPfam hit to PF00266, Aminotransferase class-V
257309005411	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309005412	S-adenosylmethionine binding site [chemical binding]; other site
257309005413	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309005414	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
257309005415	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
257309005416	HMMPfam hit to PF03054, tRNA methyl transferase
257309005417	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309005418	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
257309005419	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
257309005420	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
257309005421	active site
257309005422	catalytic site [active]
257309005423	substrate binding site [chemical binding]; other site
257309005424	HMMSmart hit to SM00479, No definition
257309005425	HMMPfam hit to PF00929, Exonuclease
257309005426	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
257309005427	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
257309005428	nucleotide binding pocket [chemical binding]; other site
257309005429	K-X-D-G motif; other site
257309005430	catalytic site [active]
257309005431	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
257309005432	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
257309005433	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
257309005434	Dimer interface [polypeptide binding]; other site
257309005435	BRCT sequence motif; other site
257309005436	HMMPfam hit to PF01653, NAD-dependent DNA ligase
257309005437	HMMSmart hit to SM00532, Ligase N family
257309005438	BlastProDom hit to PD003944, PD003944
257309005439	ScanRegExp hit to PS01055, NAD-dependent DNA ligase signature 1.
257309005440	HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold domain
257309005441	HMMPfam hit to PF03119, NAD-dependent DNA ligase C4 zinc finger domain
257309005442	ProfileScan hit to PS50120, Helix-hairpin-helix motif.
257309005443	ProfileScan hit to PS50172, BRCT domain profile.
257309005444	HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain; HMMSmart hit to SM00292, breast cancer carboxy-terminal domain
257309005445	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
257309005446	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309005447	HMMPfam hit to PF01842, ACT domain
257309005448	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
257309005449	HMMPfam hit to PF02686, Glu-tRNAGln amidotransferase C subunit
257309005450	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
257309005451	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
257309005452	HMMPfam hit to PF01425, Amidase
257309005453	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005454	ScanRegExp hit to PS00571, Amidases signature.
257309005455	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
257309005456	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309005457	Coenzyme A binding pocket [chemical binding]; other site
257309005458	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309005459	iron uptake system. Low GC content (49.78%)
257309005460	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309005461	Major Facilitator Superfamily; Region: MFS_1; pfam07690
257309005462	putative substrate translocation pore; other site
257309005463	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309005464	14 probable transmembrane helices predicted for DIP1082 by TMHMM2.0
257309005465	HMMPfam hit to PF00083, Sugar (and other) transporter
257309005466	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309005467	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309005468	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309005469	FPrintScan hit to PR01036, Tetracycline resistance protein TetB signature
257309005470	ProfileScan hit to PS50310, Alanine-rich region.
257309005471	3 probable transmembrane helices predicted for DIP1083 by TMHMM2.0
257309005472	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
257309005473	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
257309005474	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
257309005475	ABC-ATPase subunit  interface; other site
257309005476	dimer interface [polypeptide binding]; other site
257309005477	putative PBP binding regions; other site
257309005478	10 probable transmembrane helices predicted for DIP1084 by TMHMM2.0
257309005479	HMMPfam hit to PF01032, FecCD transport family
257309005480	BlastProDom hit to PD001557, PD001557
257309005481	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
257309005482	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309005483	Walker A/P-loop; other site
257309005484	ATP binding site [chemical binding]; other site
257309005485	Q-loop/lid; other site
257309005486	ABC transporter signature motif; other site
257309005487	Walker B; other site
257309005488	D-loop; other site
257309005489	H-loop/switch region; other site
257309005490	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309005491	HMMPfam hit to PF00005, ABC transporter
257309005492	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309005493	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005494	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309005495	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309005496	ScanRegExp hit to PS00211, ABC transporters family signature.
257309005497	Metal binding protein TroA_a.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148
257309005498	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
257309005499	putative ligand binding residues [chemical binding]; other site
257309005500	HMMPfam hit to PF01497, Periplasmic binding protein
257309005501	4 probable transmembrane helices predicted for DIP1087 by TMHMM2.0
257309005502	Predicted helix-turn-helix motif with score 1165 (+3.15 SD) at aa 169-190, sequence MKLTRLAKETRLSHEVVQKITQ
257309005503	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
257309005504	phosphofructokinase; Region: PFK_mixed; TIGR02483
257309005505	active site
257309005506	ADP/pyrophosphate binding site [chemical binding]; other site
257309005507	dimerization interface [polypeptide binding]; other site
257309005508	allosteric effector site; other site
257309005509	fructose-1,6-bisphosphate binding site; other site
257309005510	BlastProDom hit to PD000707, PD000707
257309005511	HMMPfam hit to PF00365, Phosphofructokinase
257309005512	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005513	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005514	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005515	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005516	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005517	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005518	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005519	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005520	HMMPfam hit to PF00365, Phosphofructokinase
257309005521	FPrintScan hit to PR00476, ATP-dependent phosphofructokinase signature
257309005522	ScanRegExp hit to PS00433, Phosphofructokinase signature.
257309005523	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
257309005524	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
257309005525	GatB domain; Region: GatB_Yqey; smart00845
257309005526	HMMPfam hit to PF02934, PET112 family, N terminal region
257309005527	HMMPfam hit to PF01162, PET112 family, C terminal region
257309005528	HMMPfam hit to PF02637, GatB/Yqey domain
257309005529	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
257309005530	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
257309005531	active site
257309005532	catalytic tetrad [active]
257309005533	HMMPfam hit to PF00248, Aldo/keto reductase
257309005534	Lysine efflux permease [General function prediction only]; Region: COG1279
257309005535	6 probable transmembrane helices predicted for DIP1091 by TMHMM2.0
257309005536	ProfileScan hit to PS50282, Bacterial transmembrane transporters, lysE/yggA family.
257309005537	HMMPfam hit to PF01810, LysE type translocator
257309005538	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
257309005539	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
257309005540	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
257309005541	dimerization interface [polypeptide binding]; other site
257309005542	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protein, lysR family
257309005543	Predicted helix-turn-helix motif with score 2081 (+6.27 SD) at aa 16-37, sequence GSFEDAAFALGISPSAVSQRIK
257309005544	ScanRegExp hit to PS00044, Bacterial regulatory proteins, lysR family signature.
257309005545	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
257309005546	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
257309005547	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
257309005548	putative dimer interface [polypeptide binding]; other site
257309005549	N-terminal domain interface [polypeptide binding]; other site
257309005550	putative substrate binding pocket (H-site) [chemical binding]; other site
257309005551	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain
257309005552	ProfileScan hit to PS50405, Glutathione S-transferase profile (C-terminal sub-domain).
257309005553	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
257309005554	Potential twin-arginine recognition motif RRSFIRK
257309005555	Predicted membrane protein [Function unknown]; Region: COG2259
257309005556	ProfileScan hit to PS50099, Proline-rich region.
257309005557	5 probable transmembrane helices predicted for DIP1095 by TMHMM2.0
257309005558	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
257309005559	HMMPfam hit to PF00920, Dehydratase
257309005560	BlastProDom hit to PD002691, PD002691
257309005561	ScanRegExp hit to PS00887, Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
257309005562	ScanRegExp hit to PS00886, Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
257309005563	Protein of unknown function (DUF2581); Region: DUF2581; pfam10756
257309005564	1 probable transmembrane helix predicted for DIP1097 by TMHMM2.0
257309005565	acetolactate synthase 1 catalytic subunit; Validated; Region: PRK07789
257309005566	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
257309005567	PYR/PP interface [polypeptide binding]; other site
257309005568	dimer interface [polypeptide binding]; other site
257309005569	TPP binding site [chemical binding]; other site
257309005570	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
257309005571	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
257309005572	TPP-binding site [chemical binding]; other site
257309005573	dimer interface [polypeptide binding]; other site
257309005574	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
257309005575	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central domain
257309005576	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
257309005577	ScanRegExp hit to PS00187, Thiamine pyrophosphate enzymes signature.
257309005578	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
257309005579	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
257309005580	putative valine binding site [chemical binding]; other site
257309005581	dimer interface [polypeptide binding]; other site
257309005582	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
257309005583	HMMPfam hit to PF01842, ACT domain
257309005584	ketol-acid reductoisomerase; Provisional; Region: PRK05479
257309005585	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
257309005586	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
257309005587	HMMPfam hit to PF01450, Acetohydroxy acid isomeroreductase, catalytic domain
257309005588	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309005589	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
257309005590	ProfileScan hit to PS50316, Histidine-rich region.
257309005591	6 probable transmembrane helices predicted for DIP1101 by TMHMM2.0
257309005592	HMMPfam hit to PF01545, Cation efflux family
257309005593	Uncharacterized conserved protein [Function unknown]; Region: COG1479
257309005594	Protein of unknown function DUF262; Region: DUF262; pfam03235
257309005595	Uncharacterized conserved protein [Function unknown]; Region: COG3472
257309005596	ScanRegExp hit to PS00436, Peroxidases active site signature.
257309005597	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
257309005598	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
257309005599	ligand binding site [chemical binding]; other site
257309005600	NAD binding site [chemical binding]; other site
257309005601	dimerization interface [polypeptide binding]; other site
257309005602	catalytic site [active]
257309005603	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
257309005604	putative L-serine binding site [chemical binding]; other site
257309005605	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
257309005606	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
257309005607	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005608	ScanRegExp hit to PS00065, D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
257309005609	ScanRegExp hit to PS00589, PTS HPR component serine phosphorylation site signature.
257309005610	HMMPfam hit to PF01842, ACT domain
257309005611	3-isopropylmalate dehydrogenase; Provisional; Region: PRK03437
257309005612	tartrate dehydrogenase; Region: TTC; TIGR02089
257309005613	HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase
257309005614	ScanRegExp hit to PS00470, Isocitrate and isopropylmalate dehydrogenases signature.
257309005615	Pseudogene. Similar to Vibrio cholerae hypothetical protein VC1291 TR:Q9KSG5 (EMBL:AE004208) (637 aa) fasta scores: E(): 2.7e-26, 26.39% id in 485 aa, and to Rhodobacter capsulatus hypothetical 66.0 kDa protein TR:O68043 (EMBL:AF010496) (608 aa) fasta scores: E(): 1.9e-23, 27.38% id in 566 aa. Contains several in-frame stop codons and a frameshift at residue 279;Conserved hypothetical protein (pseudogene)
257309005616	ProfileScan hit to PS50042, cAMP/cGMP binding motif.
257309005617	HMMPfam hit to PF00571, CBS domain
257309005618	HMMPfam hit to PF00571, CBS domain
257309005619	HMMSmart hit to SM00116, Domain in cystathionine beta-synthase and other proteins.
257309005620	ProfileScan hit to PS50147, SNF4 repeat.
257309005621	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
257309005622	2 probable transmembrane helices predicted for DIP1111 by TMHMM2.0
257309005623	Domain of unknown function (DUF2437); Region: DUF2437; pfam10370
257309005624	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
257309005625	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
257309005626	HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase
257309005627	Methyltransferase domain; Region: Methyltransf_23; pfam13489
257309005628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309005629	S-adenosylmethionine binding site [chemical binding]; other site
257309005630	isochorismate synthase DhbC; Validated; Region: PRK06923
257309005631	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
257309005632	BlastProDom hit to PD000779, PD000779
257309005633	HMMPfam hit to PF00425, chorismate binding enzyme
257309005634	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
257309005635	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
257309005636	active site
257309005637	HIGH motif; other site
257309005638	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
257309005639	active site
257309005640	KMSKS motif; other site
257309005641	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q)
257309005642	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309005643	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309005644	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309005645	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309005646	FPrintScan hit to PR00987, Glutamyl-tRNA synthetase signature
257309005647	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: LpqC; COG3509
257309005648	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309005649	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309005650	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309005651	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309005652	Predicted helix-turn-helix motif with score 1984 (+5.94 SD) at aa 28-49, sequence LTLGKVAQEVGISRTALYRYVS
257309005653	MMPL family; Region: MMPL; pfam03176
257309005654	Sterol-sensing domain of SREBP cleavage-activation; Region: Sterol-sensing; pfam12349
257309005655	MMPL family; Region: MMPL; pfam03176
257309005656	12 probable transmembrane helices predicted for DIP1118 by TMHMM2.0
257309005657	ProfileScan hit to PS50156, Sterol-sensing domain (SSD) profile.
257309005658	ProfileScan hit to PS50156, Sterol-sensing domain (SSD) profile.
257309005659	Cutinase; Region: Cutinase; pfam01083
257309005660	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005661	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
257309005662	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
257309005663	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005664	ScanRegExp hit to PS00781, Phosphoenolpyruvate carboxylase active site 1.
257309005665	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005666	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005667	HMMPfam hit to PF00311, Phosphoenolpyruvate carboxylase
257309005668	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005669	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005670	ScanRegExp hit to PS00393, Phosphoenolpyruvate carboxylase active site 2.
257309005671	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005672	FPrintScan hit to PR00150, Phosphoenolpyruvate carboxylase signature
257309005673	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
257309005674	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
257309005675	PhnA protein; Region: PhnA; pfam03831
257309005676	biotin synthase; Region: bioB; TIGR00433
257309005677	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309005678	FeS/SAM binding site; other site
257309005679	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
257309005680	HMMPfam hit to PF01792, Biotin synthase
257309005681	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
257309005682	HD domain; Region: HD_4; pfam13328
257309005683	HMMSmart hit to SM00471, Metal dependent phosphohydrolases with conserved 'HD' motif.
257309005684	Transcriptional regulator [Transcription]; Region: IclR; COG1414
257309005685	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
257309005686	putative DNA binding site [nucleotide binding]; other site
257309005687	putative Zn2+ binding site [ion binding]; other site
257309005688	Bacterial transcriptional regulator; Region: IclR; pfam01614
257309005689	HMMPfam hit to PF01614, Bacterial transcriptional regulator
257309005690	BlastProDom hit to PD002768, PD002768
257309005691	ScanRegExp hit to PS01051, Bacterial regulatory proteins, iclR family signature.
257309005692	HMMSmart hit to SM00346, helix_turn_helix isocitrate lyase regulation
257309005693	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
257309005694	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
257309005695	substrate binding site [chemical binding]; other site
257309005696	ligand binding site [chemical binding]; other site
257309005697	BlastProDom hit to PD000511, PD000511; HMMPfam hit to PF00330, Aconitase (aconitate hydratase)
257309005698	FPrintScan hit to PR00415, Aconitase signature
257309005699	FPrintScan hit to PR00415, Aconitase signature
257309005700	FPrintScan hit to PR00415, Aconitase signature
257309005701	FPrintScan hit to PR00415, Aconitase signature
257309005702	FPrintScan hit to PR00415, Aconitase signature
257309005703	FPrintScan hit to PR00415, Aconitase signature
257309005704	FPrintScan hit to PR00415, Aconitase signature
257309005705	ScanRegExp hit to PS00450, Aconitase signature 1.
257309005706	FPrintScan hit to PR00415, Aconitase signature
257309005707	FPrintScan hit to PR00415, Aconitase signature; ScanRegExp hit to PS01244, Aconitase signature 2.
257309005708	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
257309005709	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
257309005710	substrate binding site [chemical binding]; other site
257309005711	HMMPfam hit to PF00694, Aconitase C-terminal domain
257309005712	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
257309005713	active site
257309005714	Ap6A binding site [chemical binding]; other site
257309005715	nudix motif; other site
257309005716	metal binding site [ion binding]; metal-binding site
257309005717	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309005718	catalytic core [active]
257309005719	HMMPfam hit to PF00293, MutT-like domain
257309005720	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309005721	ScanRegExp hit to PS00893, Nudix hydrolase signature.
257309005722	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309005723	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
257309005724	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
257309005725	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
257309005726	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate dehydrogenase
257309005727	BlastProDom hit to PD001649, PD001649
257309005728	FPrintScan hit to PR00077, NAD-dependent glycerol-3-phosphate dehydrogenase signature
257309005729	FPrintScan hit to PR00077, NAD-dependent glycerol-3-phosphate dehydrogenase signature
257309005730	FPrintScan hit to PR00077, NAD-dependent glycerol-3-phosphate dehydrogenase signature
257309005731	FPrintScan hit to PR00077, NAD-dependent glycerol-3-phosphate dehydrogenase signature
257309005732	FPrintScan hit to PR00077, NAD-dependent glycerol-3-phosphate dehydrogenase signature
257309005733	FPrintScan hit to PR00077, NAD-dependent glycerol-3-phosphate dehydrogenase signature
257309005734	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005735	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
257309005736	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
257309005737	ATP-grasp domain; Region: ATP-grasp_4; cl17255
257309005738	HMMPfam hit to PF01820, D-ala D-ala ligase
257309005739	ScanRegExp hit to PS00843, D-alanine--D-alanine ligase signature 1.
257309005740	ScanRegExp hit to PS00844, D-alanine--D-alanine ligase signature 2.
257309005741	Protein of unknown function (DUF3515); Region: DUF3515; pfam12028
257309005742	Protein of unknown function (DUF3515); Region: DUF3515; pfam12028
257309005743	1 probable transmembrane helix predicted for DIP1132 by TMHMM2.0
257309005744	anomalous G+C content, GC bias and dinucleotide signature
257309005745	thiamine monophosphate kinase; Provisional; Region: PRK05731
257309005746	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
257309005747	ATP binding site [chemical binding]; other site
257309005748	dimerization interface [polypeptide binding]; other site
257309005749	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
257309005750	ligand binding site [chemical binding]; other site
257309005751	active site
257309005752	UGI interface [polypeptide binding]; other site
257309005753	catalytic site [active]
257309005754	BlastProDom hit to PD011327, PD011327
257309005755	HMMPfam hit to PF00315, Uracil-DNA glycosylase
257309005756	BlastProDom hit to PD001589, PD001589
257309005757	ScanRegExp hit to PS00215, Mitochondrial energy transfer proteins signature.
257309005758	ScanRegExp hit to PS00130, Uracil-DNA glycosylase signature.
257309005759	DAK2 domain; Region: Dak2; pfam02734
257309005760	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
257309005761	HMMPfam hit to PF02734, DAK2 domain
257309005762	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
257309005763	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
257309005764	generic binding surface II; other site
257309005765	ssDNA binding site; other site
257309005766	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309005767	ATP binding site [chemical binding]; other site
257309005768	putative Mg++ binding site [ion binding]; other site
257309005769	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309005770	nucleotide binding region [chemical binding]; other site
257309005771	ATP-binding site [chemical binding]; other site
257309005772	ScanRegExp hit to PS01137, TatD deoxyribonuclease signature 1.
257309005773	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309005774	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309005775	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005776	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309005777	ScanRegExp hit to PS00435, Peroxidases proximal heme-ligand signature.
257309005778	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309005779	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
257309005780	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
257309005781	carboxyltransferase (CT) interaction site; other site
257309005782	biotinylation site [posttranslational modification]; other site
257309005783	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309005784	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
257309005785	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309005786	S-adenosylmethionine binding site [chemical binding]; other site
257309005787	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309005788	ScanRegExp hit to PS00579, Ribosomal protein L29 signature.
257309005789	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309005790	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
257309005791	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
257309005792	active site
257309005793	(T/H)XGH motif; other site
257309005794	HMMPfam hit to PF01467, Cytidylyltransferase
257309005795	FPrintScan hit to PR01020, Lipopolysaccharide core biosynthesis protein signature
257309005796	FPrintScan hit to PR01020, Lipopolysaccharide core biosynthesis protein signature
257309005797	FPrintScan hit to PR01020, Lipopolysaccharide core biosynthesis protein signature
257309005798	FPrintScan hit to PR01020, Lipopolysaccharide core biosynthesis protein signature
257309005799	1 probable transmembrane helix predicted for DIP1140 by TMHMM2.0
257309005800	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
257309005801	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
257309005802	Walker A/P-loop; other site
257309005803	ATP binding site [chemical binding]; other site
257309005804	Q-loop/lid; other site
257309005805	ABC transporter signature motif; other site
257309005806	Walker B; other site
257309005807	D-loop; other site
257309005808	H-loop/switch region; other site
257309005809	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
257309005810	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309005811	HMMPfam hit to PF00005, ABC transporter
257309005812	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309005813	ScanRegExp hit to PS00211, ABC transporters family signature.
257309005814	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309005815	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005816	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
257309005817	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309005818	dimer interface [polypeptide binding]; other site
257309005819	conserved gate region; other site
257309005820	putative PBP binding loops; other site
257309005821	ABC-ATPase subunit interface; other site
257309005822	5 probable transmembrane helices predicted for DIP1143 by TMHMM2.0
257309005823	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309005824	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309005825	ScanRegExp hit to PS00225, Crystallins beta and gamma 'Greek key' motif signature.
257309005826	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
257309005827	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
257309005828	substrate binding pocket [chemical binding]; other site
257309005829	membrane-bound complex binding site; other site
257309005830	hinge residues; other site
257309005831	HMMSmart hit to SM00062, Bacterial periplasmic substrate-binding proteins
257309005832	HMMPfam hit to PF00497, Bacterial extracellular solute-binding proteins, family 3
257309005833	ProfileScan hit to PS50121, Solute binding protein/glutamate receptor domain.
257309005834	Domain of unknown function (DUF368); Region: DUF368; pfam04018
257309005835	8 probable transmembrane helices predicted for DIP1145 by TMHMM2.0
257309005836	DNA polymerase I; Provisional; Region: PRK05755
257309005837	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
257309005838	active site
257309005839	metal binding site 1 [ion binding]; metal-binding site
257309005840	putative 5' ssDNA interaction site; other site
257309005841	metal binding site 3; metal-binding site
257309005842	metal binding site 2 [ion binding]; metal-binding site
257309005843	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
257309005844	putative DNA binding site [nucleotide binding]; other site
257309005845	putative metal binding site [ion binding]; other site
257309005846	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
257309005847	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
257309005848	active site
257309005849	DNA binding site [nucleotide binding]
257309005850	catalytic site [active]
257309005851	HMMSmart hit to SM00475, 5'-3' exonuclease
257309005852	HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-like domain
257309005853	ProfileScan hit to PS50182, 5'3'-Exonuclease N-domain.
257309005854	ProfileScan hit to PS50183, 5'3'-Exonuclease I-domain.
257309005855	HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold
257309005856	HMMSmart hit to SM00279, Helix-hairpin-helix class 2 (Pol1 family) motifs
257309005857	HMMSmart hit to SM00474, 3'-5' exonuclease
257309005858	HMMPfam hit to PF00476, DNA polymerase A
257309005859	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005860	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005861	HMMSmart hit to SM00482, DNA polymerase A domain
257309005862	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005863	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005864	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005865	ScanRegExp hit to PS00447, DNA polymerase A signature.
257309005866	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005867	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005868	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005869	FPrintScan hit to PR00868, DNA-polymerase A (pol I) signature
257309005870	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309005871	S-adenosylmethionine binding site [chemical binding]; other site
257309005872	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309005873	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK07899
257309005874	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
257309005875	RNA binding site [nucleotide binding]; other site
257309005876	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
257309005877	RNA binding site [nucleotide binding]; other site
257309005878	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
257309005879	RNA binding site [nucleotide binding]; other site
257309005880	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
257309005881	RNA binding site [nucleotide binding]; other site
257309005882	HMMPfam hit to PF00575, S1 RNA binding domain
257309005883	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309005884	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309005885	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005886	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005887	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005888	HMMPfam hit to PF00575, S1 RNA binding domain
257309005889	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309005890	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309005891	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005892	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005893	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005894	HMMPfam hit to PF00575, S1 RNA binding domain
257309005895	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309005896	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309005897	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005898	HMMPfam hit to PF00575, S1 RNA binding domain
257309005899	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309005900	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309005901	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005902	FPrintScan hit to PR00681, Ribosomal protein S1 signature
257309005903	ProfileScan hit to PS50310, Alanine-rich region.
257309005904	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; cl17322
257309005905	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
257309005906	13 probable transmembrane helices predicted for DIP1149 by TMHMM2.0
257309005907	transcriptional antiterminator BglG; Provisional; Region: PRK09772
257309005908	CAT RNA binding domain; Region: CAT_RBD; smart01061
257309005909	PRD domain; Region: PRD; pfam00874
257309005910	PRD domain; Region: PRD; pfam00874
257309005911	HMMPfam hit to PF00874, Transcriptional antiterminator bglG family
257309005912	HMMPfam hit to PF03123
257309005913	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
257309005914	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
257309005915	active site turn [active]
257309005916	phosphorylation site [posttranslational modification]
257309005917	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
257309005918	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
257309005919	HPr interaction site; other site
257309005920	glycerol kinase (GK) interaction site [polypeptide binding]; other site
257309005921	active site
257309005922	phosphorylation site [posttranslational modification]
257309005923	BlastProDom hit to PD002243, PD002243; HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
257309005924	ScanRegExp hit to PS00371, PTS EIIA domains phosphorylation site signature 1.
257309005925	8 probable transmembrane helices predicted for DIP1151 by TMHMM2.0
257309005926	HMMPfam hit to PF02378, Phosphotransferase system, EIIC
257309005927	BlastProDom hit to PD001476, PD001476; HMMPfam hit to PF00367, phosphotransferase system, EIIB
257309005928	ScanRegExp hit to PS01035, PTS EIIB domains cysteine phosphorylation site signature.
257309005929	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
257309005930	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
257309005931	CoA-binding site [chemical binding]; other site
257309005932	ATP-binding [chemical binding]; other site
257309005933	HMMPfam hit to PF01121, Dephospho-CoA kinase
257309005934	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005935	ScanRegExp hit to PS01294, Dephospho-CoA kinase signature.
257309005936	Predicted helix-turn-helix motif with score 1411 (+3.99 SD) at aa 84-105, sequence ISEEKTAQLNSITHPAIRRQIR
257309005937	radical SAM protein, BA_1875 family; Region: sam_11; TIGR04053
257309005938	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309005939	FeS/SAM binding site; other site
257309005940	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
257309005941	HMMPfam hit to PF01444, moaA / nifB / pqqE family
257309005942	excinuclease ABC subunit B; Provisional; Region: PRK05298
257309005943	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309005944	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309005945	nucleotide binding region [chemical binding]; other site
257309005946	ATP-binding site [chemical binding]; other site
257309005947	Ultra-violet resistance protein B; Region: UvrB; pfam12344
257309005948	UvrB/uvrC motif; Region: UVR; pfam02151
257309005949	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309005950	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309005951	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005952	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309005953	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309005954	HMMPfam hit to PF02151, UvrB/uvrC motif; ProfileScan hit to PS50151, UvrB/uvrC motif.
257309005955	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
257309005956	Ligand Binding Site [chemical binding]; other site
257309005957	ScanRegExp hit to PS00430, TonB-dependent receptor proteins signature 1.
257309005958	HMMPfam hit to PF00582, Universal stress protein family
257309005959	FPrintScan hit to PR01438, Universal stress protein signature
257309005960	FPrintScan hit to PR01438, Universal stress protein signature
257309005961	FPrintScan hit to PR01438, Universal stress protein signature
257309005962	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
257309005963	Part of AAA domain; Region: AAA_19; pfam13245
257309005964	PhoH-like protein; Region: PhoH; cl17668
257309005965	Family description; Region: UvrD_C_2; pfam13538
257309005966	HMMPfam hit to PF00580, UvrD/REP helicase
257309005967	HMMPfam hit to PF00580, UvrD/REP helicase
257309005968	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005969	Predicted membrane protein [Function unknown]; Region: COG2259
257309005970	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
257309005971	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily
257309005972	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
257309005973	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
257309005974	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
257309005975	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
257309005976	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005977	HMMPfam hit to PF00005, ABC transporter
257309005978	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309005979	ScanRegExp hit to PS00211, ABC transporters family signature.
257309005980	HMMPfam hit to PF00005, ABC transporter
257309005981	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309005982	ScanRegExp hit to PS00190, Cytochrome c family heme-binding site signature.
257309005983	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309005984	ScanRegExp hit to PS00211, ABC transporters family signature.
257309005985	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
257309005986	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
257309005987	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
257309005988	BlastProDom hit to PD002880, PD002880; HMMPfam hit to PF00707, Translation initiation factor IF-3
257309005989	ScanRegExp hit to PS00938, Initiation factor 3 signature.
257309005990	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
257309005991	FPrintScan hit to PR00064, Ribosomal protein L35 signature
257309005992	BlastProDom hit to PD003417, PD003417; HMMPfam hit to PF01632, Ribosomal protein L35
257309005993	FPrintScan hit to PR00064, Ribosomal protein L35 signature
257309005994	FPrintScan hit to PR00064, Ribosomal protein L35 signature
257309005995	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
257309005996	23S rRNA binding site [nucleotide binding]; other site
257309005997	L21 binding site [polypeptide binding]; other site
257309005998	L13 binding site [polypeptide binding]; other site
257309005999	HMMPfam hit to PF00453, Ribosomal protein L20
257309006000	BlastProDom hit to PD002389, PD002389
257309006001	FPrintScan hit to PR00062, Ribosomal protein L20 signature
257309006002	FPrintScan hit to PR00062, Ribosomal protein L20 signature
257309006003	ScanRegExp hit to PS00937, Ribosomal protein L20 signature.
257309006004	FPrintScan hit to PR00062, Ribosomal protein L20 signature
257309006005	2 probable transmembrane helices predicted for DIP1163 by TMHMM2.0
257309006006	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
257309006007	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
257309006008	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
257309006009	HMMPfam hit to PF00588, SpoU rRNA Methylase
257309006010	BlastProDom hit to PD001243, PD001243
257309006011	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
257309006012	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
257309006013	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
257309006014	dimer interface [polypeptide binding]; other site
257309006015	motif 1; other site
257309006016	active site
257309006017	motif 2; other site
257309006018	motif 3; other site
257309006019	HMMPfam hit to PF02912, Aminoacyl tRNA synthetase class II, N-terminal domain
257309006020	HMMPfam hit to PF01409, tRNA synthetases class II (F)
257309006021	ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309006022	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
257309006023	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
257309006024	putative tRNA-binding site [nucleotide binding]; other site
257309006025	B3/4 domain; Region: B3_4; pfam03483
257309006026	tRNA synthetase B5 domain; Region: B5; smart00874
257309006027	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
257309006028	dimer interface [polypeptide binding]; other site
257309006029	motif 1; other site
257309006030	motif 3; other site
257309006031	motif 2; other site
257309006032	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
257309006033	ScanRegExp hit to PS00070, Aldehyde dehydrogenases cysteine active site.
257309006034	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
257309006035	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
257309006036	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD binding domain
257309006037	BlastProDom hit to PD003765, PD003765
257309006038	ScanRegExp hit to PS01224, N-acetyl-gamma-glutamyl-phosphate reductase active site.
257309006039	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisation domain
257309006040	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
257309006041	heterotetramer interface [polypeptide binding]; other site
257309006042	active site pocket [active]
257309006043	cleavage site
257309006044	BlastProDom hit to PD004193, PD004193
257309006045	HMMPfam hit to PF01960, ArgJ family
257309006046	ScanRegExp hit to PS01039, Bacterial extracellular solute-binding proteins, family 3 signature.
257309006047	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
257309006048	feedback inhibition sensing region; other site
257309006049	homohexameric interface [polypeptide binding]; other site
257309006050	nucleotide binding site [chemical binding]; other site
257309006051	N-acetyl-L-glutamate binding site [chemical binding]; other site
257309006052	HMMPfam hit to PF00696, Amino acid kinase
257309006053	acetylornithine aminotransferase; Provisional; Region: argD; PRK03244
257309006054	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
257309006055	inhibitor-cofactor binding pocket; inhibition site
257309006056	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309006057	catalytic residue [active]
257309006058	HMMPfam hit to PF00202, Aminotransferase class-III
257309006059	ScanRegExp hit to PS00600, Aminotransferases class-III pyridoxal-phosphate attachment site.
257309006060	ornithine carbamoyltransferase; Provisional; Region: PRK00779
257309006061	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
257309006062	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
257309006063	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
257309006064	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309006065	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309006066	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309006067	ScanRegExp hit to PS00097, Aspartate and ornithine carbamoyltransferases signature.
257309006068	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309006069	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309006070	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309006071	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309006072	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309006073	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
257309006074	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309006075	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309006076	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309006077	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309006078	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309006079	arginine repressor; Provisional; Region: PRK03341
257309006080	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
257309006081	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
257309006082	HMMPfam hit to PF01316, Arginine repressor, DNA binding domain
257309006083	BlastProDom hit to PD007402, PD007402
257309006084	FPrintScan hit to PR01467, Bacterial arginine repressor signature
257309006085	FPrintScan hit to PR01467, Bacterial arginine repressor signature
257309006086	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain
257309006087	FPrintScan hit to PR01467, Bacterial arginine repressor signature
257309006088	FPrintScan hit to PR01467, Bacterial arginine repressor signature
257309006089	argininosuccinate synthase; Provisional; Region: PRK13820
257309006090	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
257309006091	ANP binding site [chemical binding]; other site
257309006092	Substrate Binding Site II [chemical binding]; other site
257309006093	Substrate Binding Site I [chemical binding]; other site
257309006094	BlastProDom hit to PD003544, PD003544; HMMPfam hit to PF00764, Arginosuccinate synthase
257309006095	ScanRegExp hit to PS00564, Argininosuccinate synthase signature 1.
257309006096	ScanRegExp hit to PS00565, Argininosuccinate synthase signature 2.
257309006097	argininosuccinate lyase; Provisional; Region: PRK00855
257309006098	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
257309006099	active sites [active]
257309006100	tetramer interface [polypeptide binding]; other site
257309006101	HMMPfam hit to PF00206, Lyase
257309006102	FPrintScan hit to PR00145, Delta crystallin signature
257309006103	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006104	FPrintScan hit to PR00145, Delta crystallin signature
257309006105	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006106	FPrintScan hit to PR00145, Delta crystallin signature
257309006107	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006108	FPrintScan hit to PR00145, Delta crystallin signature
257309006109	FPrintScan hit to PR00145, Delta crystallin signature; FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006110	ScanRegExp hit to PS00163, Fumarate lyases signature.
257309006111	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006112	FPrintScan hit to PR00145, Delta crystallin signature
257309006113	Uncharacterized conserved protein [Function unknown]; Region: COG2835
257309006114	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
257309006115	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
257309006116	active site
257309006117	HIGH motif; other site
257309006118	dimer interface [polypeptide binding]; other site
257309006119	KMSKS motif; other site
257309006120	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y)
257309006121	ScanRegExp hit to PS00178, Aminoacyl-transfer RNA synthetases class-I signature.
257309006122	FPrintScan hit to PR01040, Tyrosyl-tRNA synthetase signature
257309006123	FPrintScan hit to PR01040, Tyrosyl-tRNA synthetase signature
257309006124	FPrintScan hit to PR01040, Tyrosyl-tRNA synthetase signature
257309006125	FPrintScan hit to PR01040, Tyrosyl-tRNA synthetase signature
257309006126	transcription termination factor Rho; Provisional; Region: PRK12678
257309006127	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
257309006128	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309006129	active site
257309006130	motif I; other site
257309006131	motif II; other site
257309006132	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309006133	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309006134	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
257309006135	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
257309006136	RNA binding surface [nucleotide binding]; other site
257309006137	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309006138	S-adenosylmethionine binding site [chemical binding]; other site
257309006139	HMMSmart hit to SM00363, S4 RNA-binding domain
257309006140	HMMPfam hit to PF01479, S4 domain
257309006141	HMMPfam hit to PF01728, FtsJ-like methyltransferase
257309006142	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03372
257309006143	ATP-NAD kinase; Region: NAD_kinase; pfam01513
257309006144	HMMPfam hit to PF01513, Domain of unknown function DUF15
257309006145	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
257309006146	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
257309006147	Walker A/P-loop; other site
257309006148	ATP binding site [chemical binding]; other site
257309006149	Q-loop/lid; other site
257309006150	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
257309006151	ABC transporter signature motif; other site
257309006152	Walker B; other site
257309006153	D-loop; other site
257309006154	H-loop/switch region; other site
257309006155	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006156	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309006157	ScanRegExp hit to PS00064, L-lactate dehydrogenase active site.
257309006158	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4825
257309006159	Thiamine pyrophosphokinase; Region: TPK; cl08415
257309006160	1 probable transmembrane helix predicted for DIP1183 by TMHMM2.0
257309006161	Protein of unknown function (DUF3186); Region: DUF3186; pfam11382
257309006162	1 probable transmembrane helix predicted for DIP1184 by TMHMM2.0
257309006163	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
257309006164	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
257309006165	dimer interface [polypeptide binding]; other site
257309006166	ADP-ribose binding site [chemical binding]; other site
257309006167	active site
257309006168	nudix motif; other site
257309006169	metal binding site [ion binding]; metal-binding site
257309006170	HMMPfam hit to PF00293, MutT-like domain
257309006171	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
257309006172	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
257309006173	active site
257309006174	Int/Topo IB signature motif; other site
257309006175	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like domain
257309006176	Predicted helix-turn-helix motif with score 1213 (+3.32 SD) at aa 10-31, sequence QWLTHLAVEKGVSDNTLSNYRR
257309006177	HMMPfam hit to PF00589, Phage integrase
257309006178	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
257309006179	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
257309006180	P-loop; other site
257309006181	Magnesium ion binding site [ion binding]; other site
257309006182	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
257309006183	Magnesium ion binding site [ion binding]; other site
257309006184	HMMPfam hit to PF00991, ParA family ATPase
257309006185	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
257309006186	HMMPfam hit to PF02616, Uncharacterized ACR, COG1354
257309006187	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
257309006188	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase
257309006189	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
257309006190	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309006191	POT family; Region: PTR2; cl17359
257309006192	14 probable transmembrane helices predicted for DIP1190 by TMHMM2.0
257309006193	HMMPfam hit to PF00854, POT family
257309006194	HMMPfam hit to PF00854, POT family
257309006195	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05630
257309006196	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
257309006197	inhibitor-cofactor binding pocket; inhibition site
257309006198	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309006199	catalytic residue [active]
257309006200	HMMPfam hit to PF00202, Aminotransferase class-III
257309006201	ScanRegExp hit to PS00600, Aminotransferases class-III pyridoxal-phosphate attachment site.
257309006202	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
257309006203	AAA domain; Region: AAA_26; pfam13500
257309006204	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase
257309006205	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
257309006206	11 probable transmembrane helices predicted for DIP1193 by TMHMM2.0
257309006207	HMMPfam hit to PF00999, Sodium/hydrogen exchanger family
257309006208	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309006209	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309006210	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309006211	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309006212	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309006213	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
257309006214	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
257309006215	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
257309006216	RNA binding surface [nucleotide binding]; other site
257309006217	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
257309006218	active site
257309006219	HMMSmart hit to SM00363, S4 RNA-binding domain
257309006220	HMMPfam hit to PF01479, S4 domain
257309006221	HMMPfam hit to PF00849, RNA pseudouridylate synthase
257309006222	ScanRegExp hit to PS01149, Rsu family of pseudouridine synthase signature.
257309006223	cytidylate kinase; Provisional; Region: cmk; PRK00023
257309006224	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
257309006225	CMP-binding site; other site
257309006226	The sites determining sugar specificity; other site
257309006227	FPrintScan hit to PR00988, Uridine kinase signature
257309006228	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309006229	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006230	HMMPfam hit to PF02224, Cytidylate kinase
257309006231	FPrintScan hit to PR00988, Uridine kinase signature
257309006232	GTP-binding protein Der; Reviewed; Region: PRK03003
257309006233	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
257309006234	G1 box; other site
257309006235	GTP/Mg2+ binding site [chemical binding]; other site
257309006236	Switch I region; other site
257309006237	G2 box; other site
257309006238	Switch II region; other site
257309006239	G3 box; other site
257309006240	G4 box; other site
257309006241	G5 box; other site
257309006242	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
257309006243	G1 box; other site
257309006244	GTP/Mg2+ binding site [chemical binding]; other site
257309006245	Switch I region; other site
257309006246	G2 box; other site
257309006247	G3 box; other site
257309006248	Switch II region; other site
257309006249	G4 box; other site
257309006250	G5 box; other site
257309006251	FPrintScan hit to PR00449, Transforming protein P21 ras signature
257309006252	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006253	HMMPfam hit to PF01926, GTPase of unknown function
257309006254	FPrintScan hit to PR00449, Transforming protein P21 ras signature
257309006255	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309006256	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006257	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309006258	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309006259	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
257309006260	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
257309006261	12 probable transmembrane helices predicted for DIP1198 by TMHMM2.0
257309006262	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309006263	S-adenosylmethionine binding site [chemical binding]; other site
257309006264	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309006265	Putative esterase; Region: Esterase; pfam00756
257309006266	4 probable transmembrane helices predicted for DIP1200 by TMHMM2.0
257309006267	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309006268	hypothetical protein; Provisional; Region: PRK04233
257309006269	SEC-C motif; Region: SEC-C; pfam02810
257309006270	HMMPfam hit to PF02810, SEC-C motif
257309006271	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
257309006272	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309006273	preprotein translocase subunit SecA; Reviewed; Region: PRK12326
257309006274	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
257309006275	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
257309006276	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309006277	nucleotide binding region [chemical binding]; other site
257309006278	ATP-binding site [chemical binding]; other site
257309006279	FPrintScan hit to PR00906, SecA protein signature
257309006280	HMMPfam hit to PF01043, SecA protein, amino terminal region
257309006281	FPrintScan hit to PR00906, SecA protein signature
257309006282	FPrintScan hit to PR00906, SecA protein signature
257309006283	FPrintScan hit to PR00906, SecA protein signature
257309006284	FPrintScan hit to PR00906, SecA protein signature
257309006285	FPrintScan hit to PR00906, SecA protein signature
257309006286	HMMPfam hit to PF00271, Helicase conserved C-terminal domain
257309006287	ScanRegExp hit to PS01312, Protein secA signatures.
257309006288	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
257309006289	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
257309006290	phosphopeptide binding site; other site
257309006291	HMMSmart hit to SM00240, Forkhead associated domain
257309006292	HMMPfam hit to PF00498, FHA domain
257309006293	ProfileScan hit to PS50006, Forkhead-associated (FHA) domain profile.
257309006294	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
257309006295	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
257309006296	DNA binding residues [nucleotide binding]
257309006297	HMMSmart hit to SM00422, helix_turn_helix, mercury resistance
257309006298	HMMPfam hit to PF00376, Bacterial regulatory proteins, merR family
257309006299	Bifunctional nuclease; Region: DNase-RNase; pfam02577
257309006300	HMMPfam hit to PF02577, Uncharacterized ACR, COG1259
257309006301	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
257309006302	DNA binding residues [nucleotide binding]
257309006303	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
257309006304	putative dimer interface [polypeptide binding]; other site
257309006305	HMMSmart hit to SM00422, helix_turn_helix, mercury resistance
257309006306	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
257309006307	metal ion-dependent adhesion site (MIDAS); other site
257309006308	HMMSmart hit to SM00327, von Willebrand factor (vWF) type A domain
257309006309	ProfileScan hit to PS50234, VWFA domain profile.
257309006310	1 probable transmembrane helix predicted for DIP1208 by TMHMM2.0
257309006311	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
257309006312	Domain of unknown function DUF21; Region: DUF21; pfam01595
257309006313	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
257309006314	HMMPfam hit to PF00571, CBS domain
257309006315	ProfileScan hit to PS50147, SNF4 repeat.
257309006316	HMMPfam hit to PF00571, CBS domain
257309006317	HMMPfam hit to PF01595, Domain of unknown function DUF21
257309006318	4 probable transmembrane helices predicted for DIP1210 by TMHMM2.0
257309006319	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
257309006320	Domain of unknown function DUF21; Region: DUF21; pfam01595
257309006321	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
257309006322	Transporter associated domain; Region: CorC_HlyC; smart01091
257309006323	HMMPfam hit to PF00571, CBS domain
257309006324	HMMPfam hit to PF00571, CBS domain
257309006325	HMMPfam hit to PF01595, Domain of unknown function DUF21
257309006326	3 probable transmembrane helices predicted for DIP1211 by TMHMM2.0
257309006327	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
257309006328	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
257309006329	ATP binding site [chemical binding]; other site
257309006330	Mg++ binding site [ion binding]; other site
257309006331	motif III; other site
257309006332	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309006333	nucleotide binding region [chemical binding]; other site
257309006334	ATP-binding site [chemical binding]; other site
257309006335	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309006336	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309006337	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309006338	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309006339	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006340	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
257309006341	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
257309006342	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
257309006343	HMMPfam hit to PF00393, 6-phosphogluconate dehydrogenase
257309006344	FPrintScan hit to PR00076, 6-phosphogluconate dehydrogenase signature
257309006345	FPrintScan hit to PR00076, 6-phosphogluconate dehydrogenase signature
257309006346	ScanRegExp hit to PS00461, 6-phosphogluconate dehydrogenase signature.
257309006347	FPrintScan hit to PR00076, 6-phosphogluconate dehydrogenase signature
257309006348	FPrintScan hit to PR00076, 6-phosphogluconate dehydrogenase signature
257309006349	FPrintScan hit to PR00076, 6-phosphogluconate dehydrogenase signature
257309006350	FPrintScan hit to PR00076, 6-phosphogluconate dehydrogenase signature
257309006351	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
257309006352	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
257309006353	CoenzymeA binding site [chemical binding]; other site
257309006354	subunit interaction site [polypeptide binding]; other site
257309006355	PHB binding site; other site
257309006356	HMMPfam hit to PF02584, Uncharacterized protein PaaI, COG2050
257309006357	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
257309006358	Mycobacterium tuberculosis CorA-like subfamily; Region: MtCorA-like; cd12830
257309006359	oligomer interface [polypeptide binding]; other site
257309006360	metal binding site [ion binding]; metal-binding site
257309006361	metal binding site [ion binding]; metal-binding site
257309006362	putative Cl binding site [ion binding]; other site
257309006363	basic sphincter; other site
257309006364	hydrophobic gate; other site
257309006365	periplasmic entrance; other site
257309006366	HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein
257309006367	2 probable transmembrane helices predicted for DIP1215 by TMHMM2.0
257309006368	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309006369	S-adenosylmethionine binding site [chemical binding]; other site
257309006370	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309006371	ProfileScan hit to PS50124, Generic methyl-transferase profile.
257309006372	sortase B anchoring signal. NPQTN - NPLTN
257309006373	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
257309006374	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
257309006375	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
257309006376	1 probable transmembrane helix predicted for DIP1217 by TMHMM2.0
257309006377	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase
257309006378	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309006379	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309006380	ProfileScan hit to PS50205, NAD binding site.
257309006381	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309006382	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
257309006383	Pseudogene. Similar to Streptomyces coelicolor oxidoreductase SC5F1.26 SWALL:Q9F3A3 (EMBL:AL450165) (998 aa) fasta scores: E(): 2.5e-23, 48.05% id in 154 aa, and to Pseudomonas aeruginosa probable ferredoxin PA4772 SWALL:Q9HV36 (EMBL:AE004890) (938 aa) fasta scores: E(): 2.3e-14, 35.33% id in 150 aa. Presents a frameshift at residue 74 and lacks stop codon; oxidoreductase (pseudogene)
257309006384	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
257309006385	Sodium Bile acid symporter family; Region: SBF; pfam01758
257309006386	9 probable transmembrane helices predicted for DIP1221 by TMHMM2.0
257309006387	HMMPfam hit to PF01758, Sodium Bile acid symporter family
257309006388	2 probable transmembrane helices predicted for DIP1222 by TMHMM2.0
257309006389	YceI-like domain; Region: YceI; pfam04264
257309006390	1 probable transmembrane helix predicted for DIP1223 by TMHMM2.0
257309006391	Domain of unknown function (DUF4109); Region: DUF4109; pfam13397
257309006392	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
257309006393	Ligand binding site; other site
257309006394	Putative Catalytic site; other site
257309006395	DXD motif; other site
257309006396	HMMPfam hit to PF00535, Glycosyl transferase
257309006397	ProfileScan hit to PS50167, General Glycosyltransferase domain.
257309006398	Apolipoprotein N-acyltransferase [Cell envelope biogenesis, outer membrane]; Region: Lnt; COG0815
257309006399	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
257309006400	putative active site [active]
257309006401	catalytic triad [active]
257309006402	putative dimer interface [polypeptide binding]; other site
257309006403	8 probable transmembrane helices predicted for DIP1227 by TMHMM2.0
257309006404	HMMPfam hit to PF00795, Carbon-nitrogen hydrolase
257309006405	ProfileScan hit to PS50263, Nitrilase/cyanide-hydratase/amidase catalytic domain (active site Cys)
257309006406	phage T7 F exclusion suppressor FxsA; Reviewed; Region: fxsA; PRK11463
257309006407	2 probable transmembrane helices predicted for DIP1228 by TMHMM2.0
257309006408	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
257309006409	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
257309006410	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
257309006411	HMMPfam hit to PF02514, CobN/Magnesium Chelatase
257309006412	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309006413	ScanRegExp hit to PS00225, Crystallins beta and gamma 'Greek key' motif signature.
257309006414	precorrin-3B synthase; Region: CobG; TIGR02435
257309006415	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
257309006416	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
257309006417	HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S domain
257309006418	precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285
257309006419	Precorrin-8X methylmutase; Region: CbiC; pfam02570
257309006420	HMMPfam hit to PF02570, Precorrin-8X methylmutase
257309006421	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
257309006422	active site
257309006423	SAM binding site [chemical binding]; other site
257309006424	homodimer interface [polypeptide binding]; other site
257309006425	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
257309006426	homodimer interface [polypeptide binding]; other site
257309006427	active site
257309006428	SAM binding site [chemical binding]; other site
257309006429	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309006430	ScanRegExp hit to PS00840, Uroporphyrin-III C-methyltransferase signature 2.
257309006431	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309006432	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
257309006433	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
257309006434	HMMPfam hit to PF02571, Precorrin-6x reductase CbiJ/CobK
257309006435	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
257309006436	active site
257309006437	SAM binding site [chemical binding]; other site
257309006438	homodimer interface [polypeptide binding]; other site
257309006439	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309006440	ScanRegExp hit to PS00840, Uroporphyrin-III C-methyltransferase signature 2.
257309006441	ScanRegExp hit to PS00839, Uroporphyrin-III C-methyltransferase signature 1.
257309006442	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
257309006443	active site
257309006444	putative homodimer interface [polypeptide binding]; other site
257309006445	SAM binding site [chemical binding]; other site
257309006446	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
257309006447	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309006448	S-adenosylmethionine binding site [chemical binding]; other site
257309006449	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309006450	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309006451	hypothetical protein; Provisional; Region: PRK05599
257309006452	short chain dehydrogenase; Provisional; Region: PRK08251
257309006453	NAD(P) binding site [chemical binding]; other site
257309006454	active site
257309006455	HMMPfam hit to PF00106, short chain dehydrogenase
257309006456	ScanRegExp hit to PS00061, Short-chain dehydrogenases/reductases family signature.
257309006457	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
257309006458	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
257309006459	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
257309006460	active site
257309006461	HMMPfam hit to PF00557, metallopeptidase M24
257309006462	DEAD-like helicases superfamily; Region: DEXDc; smart00487
257309006463	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309006464	ATP binding site [chemical binding]; other site
257309006465	putative Mg++ binding site [ion binding]; other site
257309006466	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309006467	nucleotide binding region [chemical binding]; other site
257309006468	ATP-binding site [chemical binding]; other site
257309006469	DSHCT (NUC185) domain; Region: DSHCT; pfam08148
257309006470	HMMPfam hit to PF00271, Helicase conserved C-terminal domain
257309006471	HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309006472	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309006473	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309006474	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006475	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
257309006476	HMMPfam hit to PF00588, SpoU rRNA Methylase
257309006477	BlastProDom hit to PD001243, PD001243
257309006478	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
257309006479	6 probable transmembrane helices predicted for DIP1241 by TMHMM2.0
257309006480	HMMPfam hit to PF00902, MttB family UPF0032
257309006481	ScanRegExp hit to PS01218, Uncharacterized protein family UPF0032 signature.
257309006482	twin arginine translocase protein A; Provisional; Region: tatA; PRK00191
257309006483	mttA/Hcf106 family; Region: MttA_Hcf106; pfam02416
257309006484	ProfileScan hit to PS50322, Glutamine-rich region.
257309006485	HMMPfam hit to PF02416, mttA/Hcf106 family
257309006486	1 probable transmembrane helix predicted for DIP1242 by TMHMM2.0
257309006487	Predicted transcriptional regulator [Transcription]; Region: COG2378
257309006488	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
257309006489	WYL domain; Region: WYL; pfam13280
257309006490	WYL domain; Region: WYL; pfam13280
257309006491	proteasome accessory factor PafA; Region: pupylate_PafA; TIGR03686
257309006492	HMMPfam hit to PF03136
257309006493	Pup-like protein; Region: Pup; pfam05639
257309006494	proteasome accessory factor PafA2; Region: pupylate_PafA2; TIGR03688
257309006495	HMMPfam hit to PF03136
257309006496	proteasome ATPase; Region: pup_AAA; TIGR03689
257309006497	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309006498	Walker A motif; other site
257309006499	ATP binding site [chemical binding]; other site
257309006500	Walker B motif; other site
257309006501	arginine finger; other site
257309006502	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309006503	FPrintScan hit to PR00819, CbxX/CfqX superfamily signature
257309006504	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309006505	ScanRegExp hit to PS00674, AAA-protein family signature.
257309006506	FPrintScan hit to PR00819, CbxX/CfqX superfamily signature
257309006507	FPrintScan hit to PR00819, CbxX/CfqX superfamily signature
257309006508	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006509	tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Translation, ribosomal structure and biogenesis]; Region: GCD14; COG2519
257309006510	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309006511	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309006512	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
257309006513	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
257309006514	active site
257309006515	metal binding site [ion binding]; metal-binding site
257309006516	HMMPfam hit to PF02127, Aminopeptidase I zinc metalloprotease (M18)
257309006517	FPrintScan hit to PR00932, Aminopeptidase I zinc metalloprotease (M18) signature
257309006518	FPrintScan hit to PR00932, Aminopeptidase I zinc metalloprotease (M18) signature
257309006519	FPrintScan hit to PR00932, Aminopeptidase I zinc metalloprotease (M18) signature
257309006520	FPrintScan hit to PR00932, Aminopeptidase I zinc metalloprotease (M18) signature
257309006521	FPrintScan hit to PR00932, Aminopeptidase I zinc metalloprotease (M18) signature
257309006522	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
257309006523	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
257309006524	Predicted helix-turn-helix motif with score 1259 (+3.47 SD) at aa 42-63, sequence ISHYDLAKQLHITETSLDHFIA
257309006525	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
257309006526	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
257309006527	Potassium binding sites [ion binding]; other site
257309006528	Cesium cation binding sites [ion binding]; other site
257309006529	HMMPfam hit to PF01268, Formate--tetrahydrofolate ligase
257309006530	ScanRegExp hit to PS00721, Formate--tetrahydrofolate ligase signature 1.
257309006531	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
257309006532	Aspartase; Region: Aspartase; cd01357
257309006533	active sites [active]
257309006534	tetramer interface [polypeptide binding]; other site
257309006535	HMMPfam hit to PF00206, Lyase
257309006536	FPrintScan hit to PR00145, Delta crystallin signature; FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006537	ScanRegExp hit to PS00163, Fumarate lyases signature.
257309006538	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006539	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006540	FPrintScan hit to PR00145, Delta crystallin signature
257309006541	FPrintScan hit to PR00145, Delta crystallin signature
257309006542	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309006543	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
257309006544	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
257309006545	11 probable transmembrane helices predicted for DIP1255 by TMHMM2.0
257309006546	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
257309006547	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
257309006548	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
257309006549	BlastProDom hit to PD003516, PD003516; HMMPfam hit to PF01634, ATP phosphoribosyltransferase
257309006550	ScanRegExp hit to PS01316, ATP phosphoribosyltransferase signature.
257309006551	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Mycobacterium tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs; Region: NTP-PPase_HisE; cd11547
257309006552	homodimer interface [polypeptide binding]; other site
257309006553	putative metal binding site [ion binding]; other site
257309006554	HMMPfam hit to PF01503, Phosphoribosyl-ATP pyrophosphohydrolase
257309006555	BlastProDom hit to PD002611, PD002611
257309006556	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
257309006557	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309006558	motif II; other site
257309006559	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309006560	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
257309006561	5-methyltetrahydrofolate--homocysteine methyltransferase; Region: metH; TIGR02082
257309006562	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
257309006563	substrate binding pocket [chemical binding]; other site
257309006564	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
257309006565	B12 binding site [chemical binding]; other site
257309006566	cobalt ligand [ion binding]; other site
257309006567	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
257309006568	HMMPfam hit to PF02965, Vitamin B12 dependent methionine synthase, activation domain
257309006569	HMMPfam hit to PF02310, B12 binding domain
257309006570	HMMPfam hit to PF02607, B12 binding domain
257309006571	HMMPfam hit to PF02574, Homocysteine S-methyltransferase
257309006572	cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Region: mycothiol_MshC; TIGR03447
257309006573	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309006574	active site
257309006575	HIGH motif; other site
257309006576	nucleotide binding site [chemical binding]; other site
257309006577	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309006578	active site
257309006579	KMSKS motif; other site
257309006580	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
257309006581	tRNA binding surface [nucleotide binding]; other site
257309006582	anticodon binding site; other site
257309006583	HMMPfam hit to PF01406, tRNA synthetases class I (C)
257309006584	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309006585	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309006586	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309006587	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309006588	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK12554
257309006589	5 probable transmembrane helices predicted for DIP1262 by TMHMM2.0
257309006590	HMMPfam hit to PF02673, Bacitracin resistance protein BacA
257309006591	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
257309006592	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
257309006593	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
257309006594	quinone interaction residues [chemical binding]; other site
257309006595	active site
257309006596	catalytic residues [active]
257309006597	FMN binding site [chemical binding]; other site
257309006598	substrate binding site [chemical binding]; other site
257309006599	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase
257309006600	ScanRegExp hit to PS00911, Dihydroorotate dehydrogenase signature 1.
257309006601	ScanRegExp hit to PS00912, Dihydroorotate dehydrogenase signature 2.
257309006602	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
257309006603	substrate binding site [chemical binding]; other site
257309006604	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
257309006605	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
257309006606	HTH-like domain; Region: HTH_21; pfam13276
257309006607	Integrase core domain; Region: rve; pfam00665
257309006608	Integrase core domain; Region: rve_2; pfam13333
257309006609	1 probable transmembrane helix predicted for DIP1266 by TMHMM2.0
257309006610	HMMPfam hit to PF00665, Integrase core domain
257309006611	Pseudogene. Similar to Streptomyces coelicolor oxidoreductase SCM11.12c SWALL:Q9RIU9 (EMBL:AL133278) (500 aa) fasta scores: E(): 8.9e-41, 52.1% id in 428 aa. Presents multiple frameshifts at residues 33, 93, 121, 293 and 299; oxidoreductase (pseudogene)
257309006612	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
257309006613	active site residue [active]
257309006614	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
257309006615	active site residue [active]
257309006616	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309006617	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309006618	HMMPfam hit to PF00581, Rhodanese-like domain
257309006619	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309006620	membrane ATPase/protein kinase; Provisional; Region: PRK09435
257309006621	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
257309006622	Walker A; other site
257309006623	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006624	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
257309006625	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
257309006626	active site
257309006627	substrate binding site [chemical binding]; other site
257309006628	coenzyme B12 binding site [chemical binding]; other site
257309006629	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
257309006630	B12 binding site [chemical binding]; other site
257309006631	cobalt ligand [ion binding]; other site
257309006632	HMMPfam hit to PF02310, B12 binding domain
257309006633	HMMPfam hit to PF01642, Methylmalonyl-CoA mutase
257309006634	methylmalonyl-CoA mutase, heterodimeric type, beta chain; Region: mmCoA_mut_beta; TIGR00642
257309006635	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
257309006636	heterodimer interface [polypeptide binding]; other site
257309006637	substrate interaction site [chemical binding]; other site
257309006638	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
257309006639	HMMPfam hit to PF01642, Methylmalonyl-CoA mutase
257309006640	Uncharacterized conserved protein [Function unknown]; Region: COG0398
257309006641	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
257309006642	5 probable transmembrane helices predicted for DIP1274 by TMHMM2.0
257309006643	ScanRegExp hit to PS01159, WW/rsp5/WWP domain signature.
257309006644	ProfileScan hit to PS50116, Helix-Turn-Helix fis-type.
257309006645	Predicted helix-turn-helix motif with score 2120 (+6.41 SD) at aa 143-164, sequence LNQIEAAEELGISKQAISQRLQ
257309006646	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
257309006647	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
257309006648	HMMPfam hit to PF01145, SPFH domain / Band 7 family
257309006649	FPrintScan hit to PR00721, Stomatin signature
257309006650	HMMSmart hit to SM00244, prohibitin homologues
257309006651	FPrintScan hit to PR00721, Stomatin signature
257309006652	ScanRegExp hit to PS01270, Band 7 protein family signature.
257309006653	FPrintScan hit to PR00721, Stomatin signature
257309006654	FPrintScan hit to PR00721, Stomatin signature
257309006655	FPrintScan hit to PR00721, Stomatin signature
257309006656	FPrintScan hit to PR00721, Stomatin signature
257309006657	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
257309006658	2 probable transmembrane helices predicted for DIP1277 by TMHMM2.0
257309006659	Protein of unknown function (DUF3097); Region: DUF3097; pfam11296
257309006660	ferrochelatase; Reviewed; Region: hemH; PRK00035
257309006661	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
257309006662	C-terminal domain interface [polypeptide binding]; other site
257309006663	active site
257309006664	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
257309006665	active site
257309006666	N-terminal domain interface [polypeptide binding]; other site
257309006667	HMMPfam hit to PF00762, Ferrochelatase
257309006668	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
257309006669	NlpC/P60 family; Region: NLPC_P60; pfam00877
257309006670	HMMPfam hit to PF00877, NLP/P60 family
257309006671	ProfileScan hit to PS50310, Alanine-rich region.
257309006672	aconitate hydratase; Validated; Region: PRK09277
257309006673	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
257309006674	substrate binding site [chemical binding]; other site
257309006675	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
257309006676	ligand binding site [chemical binding]; other site
257309006677	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
257309006678	substrate binding site [chemical binding]; other site
257309006679	HMMPfam hit to PF00330, Aconitase (aconitate hydratase)
257309006680	BlastProDom hit to PD000511, PD000511
257309006681	FPrintScan hit to PR00415, Aconitase signature
257309006682	FPrintScan hit to PR00415, Aconitase signature
257309006683	FPrintScan hit to PR00415, Aconitase signature
257309006684	FPrintScan hit to PR00415, Aconitase signature
257309006685	FPrintScan hit to PR00415, Aconitase signature
257309006686	FPrintScan hit to PR00415, Aconitase signature
257309006687	FPrintScan hit to PR00415, Aconitase signature
257309006688	HMMPfam hit to PF00330, Aconitase (aconitate hydratase)
257309006689	ScanRegExp hit to PS00450, Aconitase signature 1.
257309006690	FPrintScan hit to PR00415, Aconitase signature
257309006691	FPrintScan hit to PR00415, Aconitase signature; ScanRegExp hit to PS01244, Aconitase signature 2.
257309006692	HMMPfam hit to PF00694, Aconitase C-terminal domain
257309006693	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309006694	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309006695	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309006696	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309006697	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309006698	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
257309006699	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
257309006700	catalytic triad [active]
257309006701	ScanRegExp hit to PS00144, Asparaginase / glutaminase active site signature 1.
257309006702	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
257309006703	HMMPfam hit to PF01842, ACT domain
257309006704	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
257309006705	2 probable transmembrane helices predicted for DIP1288 by TMHMM2.0
257309006706	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
257309006707	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
257309006708	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309006709	Walker A/P-loop; other site
257309006710	ATP binding site [chemical binding]; other site
257309006711	Q-loop/lid; other site
257309006712	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
257309006713	ABC transporter signature motif; other site
257309006714	Walker B; other site
257309006715	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
257309006716	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309006717	HMMPfam hit to PF00005, ABC transporter
257309006718	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309006719	ScanRegExp hit to PS00211, ABC transporters family signature.
257309006720	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309006721	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006722	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309006723	HMMPfam hit to PF00005, ABC transporter
257309006724	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309006725	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006726	ScanRegExp hit to PS00211, ABC transporters family signature.
257309006727	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309006728	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006729	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
257309006730	BlastProDom hit to PD005595, PD005595
257309006731	HMMPfam hit to PF01883, Domain of unknown function DUF59
257309006732	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
257309006733	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
257309006734	trimerization site [polypeptide binding]; other site
257309006735	active site
257309006736	HMMPfam hit to PF01592, NifU-like N terminal domain
257309006737	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
257309006738	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
257309006739	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
257309006740	catalytic residue [active]
257309006741	HMMPfam hit to PF00266, Aminotransferase class-V
257309006742	ScanRegExp hit to PS00595, Aminotransferases class-V pyridoxal-phosphate attachment site.
257309006743	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
257309006744	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
257309006745	Walker A/P-loop; other site
257309006746	ATP binding site [chemical binding]; other site
257309006747	Q-loop/lid; other site
257309006748	ABC transporter signature motif; other site
257309006749	Walker B; other site
257309006750	D-loop; other site
257309006751	H-loop/switch region; other site
257309006752	HMMPfam hit to PF00005, ABC transporter
257309006753	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309006754	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309006755	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006756	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
257309006757	FeS assembly protein SufD; Region: sufD; TIGR01981
257309006758	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051)
257309006759	ScanRegExp hit to PS00215, Mitochondrial energy transfer proteins signature.
257309006760	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
257309006761	FeS assembly protein SufB; Region: sufB; TIGR01980
257309006762	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051)
257309006763	Predicted transcriptional regulator [Transcription]; Region: COG2345
257309006764	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
257309006765	putative DNA binding site [nucleotide binding]; other site
257309006766	putative Zn2+ binding site [ion binding]; other site
257309006767	HMMPfam hit to PF02178, AT hook motif
257309006768	Predicted helix-turn-helix motif with score 1296 (+3.60 SD) at aa 30-51, sequence VTATQLGQQLNLSATGIRRHLD
257309006769	carotene biosynthesis associated membrane protein; Region: crt_membr; TIGR03459
257309006770	14 probable transmembrane helices predicted for DIP1297 by TMHMM2.0
257309006771	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309006772	ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263
257309006773	Walker A/P-loop; other site
257309006774	ATP binding site [chemical binding]; other site
257309006775	Q-loop/lid; other site
257309006776	ABC transporter signature motif; other site
257309006777	Walker B; other site
257309006778	D-loop; other site
257309006779	H-loop/switch region; other site
257309006780	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309006781	HMMPfam hit to PF00005, ABC transporter
257309006782	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309006783	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006784	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309006785	ScanRegExp hit to PS00211, ABC transporters family signature.
257309006786	ABC-2 type transporter; Region: ABC2_membrane; cl17235
257309006787	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
257309006788	6 probable transmembrane helices predicted for DIP1299 by TMHMM2.0
257309006789	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
257309006790	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
257309006791	HMMPfam hit to PF02628, Cytochrome oxidase assembly protein
257309006792	8 probable transmembrane helices predicted for DIP1300 by TMHMM2.0
257309006793	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
257309006794	UbiA prenyltransferase family; Region: UbiA; pfam01040
257309006795	9 probable transmembrane helices predicted for DIP1301 by TMHMM2.0
257309006796	HMMPfam hit to PF01040, UbiA prenyltransferase
257309006797	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
257309006798	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
257309006799	TPP-binding site [chemical binding]; other site
257309006800	dimer interface [polypeptide binding]; other site
257309006801	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
257309006802	PYR/PP interface [polypeptide binding]; other site
257309006803	dimer interface [polypeptide binding]; other site
257309006804	TPP binding site [chemical binding]; other site
257309006805	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
257309006806	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate binding domain
257309006807	ScanRegExp hit to PS00801, Transketolase signature 1.
257309006808	HMMPfam hit to PF02779, Transketolase, pyridine binding domain
257309006809	ScanRegExp hit to PS00802, Transketolase signature 2.
257309006810	HMMPfam hit to PF02780, Transketolase, C-terminal domain
257309006811	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
257309006812	putative active site [active]
257309006813	transaldolase; Provisional; Region: PRK03903
257309006814	catalytic residue [active]
257309006815	HMMPfam hit to PF00923, Transaldolase
257309006816	ScanRegExp hit to PS01054, Transaldolase signature 1.
257309006817	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
257309006818	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
257309006819	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
257309006820	HMMPfam hit to PF00479, Glucose-6-phosphate dehydrogenase, NAD binding domain
257309006821	BlastProDom hit to PD001129, PD001129
257309006822	FPrintScan hit to PR00079, Glucose-6-phosphate dehydrogenase signature
257309006823	FPrintScan hit to PR00079, Glucose-6-phosphate dehydrogenase signature
257309006824	ScanRegExp hit to PS00069, Glucose-6-phosphate dehydrogenase active site.
257309006825	HMMPfam hit to PF02781, Glucose-6-phosphate dehydrogenase, C-terminal domain
257309006826	FPrintScan hit to PR00079, Glucose-6-phosphate dehydrogenase signature
257309006827	FPrintScan hit to PR00079, Glucose-6-phosphate dehydrogenase signature
257309006828	FPrintScan hit to PR00079, Glucose-6-phosphate dehydrogenase signature
257309006829	glucose-6-phosphate dehydrogenase assembly protein OpcA; Region: OpcA; TIGR00534
257309006830	Glucose-6-phosphate dehydrogenase subunit; Region: OpcA_G6PD_assem; pfam10128
257309006831	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
257309006832	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
257309006833	putative active site [active]
257309006834	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
257309006835	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
257309006836	2 probable transmembrane helices predicted for DIP1307 by TMHMM2.0
257309006837	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
257309006838	triosephosphate isomerase; Provisional; Region: PRK14567
257309006839	substrate binding site [chemical binding]; other site
257309006840	dimer interface [polypeptide binding]; other site
257309006841	catalytic triad [active]
257309006842	BlastProDom hit to PD001005, PD001005; HMMPfam hit to PF00121, Triosephosphate isomerase
257309006843	ScanRegExp hit to PS00171, Triosephosphate isomerase active site.
257309006844	Phosphoglycerate kinase; Region: PGK; pfam00162
257309006845	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
257309006846	substrate binding site [chemical binding]; other site
257309006847	hinge regions; other site
257309006848	ADP binding site [chemical binding]; other site
257309006849	catalytic site [active]
257309006850	HMMPfam hit to PF00162, Phosphoglycerate kinase
257309006851	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006852	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006853	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006854	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006855	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006856	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006857	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006858	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006859	FPrintScan hit to PR00477, Phosphoglycerate kinase signature
257309006860	ScanRegExp hit to PS00111, Phosphoglycerate kinase signature.
257309006861	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
257309006862	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
257309006863	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
257309006864	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
257309006865	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309006866	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309006867	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309006868	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309006869	ScanRegExp hit to PS00071, Glyceraldehyde 3-phosphate dehydrogenase active site.
257309006870	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
257309006871	FPrintScan hit to PR00078, Glyceraldehyde-3-phosphate dehydrogenase signature
257309006872	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
257309006873	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
257309006874	HMMPfam hit to PF02650, Uncharacterized BCR, COG1481
257309006875	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
257309006876	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
257309006877	phosphate binding site [ion binding]; other site
257309006878	putative substrate binding pocket [chemical binding]; other site
257309006879	dimer interface [polypeptide binding]; other site
257309006880	HMMPfam hit to PF01933, Uncharacterised protein family UPF0052
257309006881	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
257309006882	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
257309006883	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
257309006884	GIY-YIG motif/motif A; other site
257309006885	active site
257309006886	catalytic site [active]
257309006887	putative DNA binding site [nucleotide binding]; other site
257309006888	metal binding site [ion binding]; metal-binding site
257309006889	UvrB/uvrC motif; Region: UVR; pfam02151
257309006890	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
257309006891	ProfileScan hit to PS50120, Helix-hairpin-helix motif.
257309006892	BlastProDom hit to PD005870, PD005870
257309006893	ProfileScan hit to PS50165, UvrC homology region 2.
257309006894	HMMPfam hit to PF02151, UvrB/uvrC motif; ProfileScan hit to PS50151, UvrB/uvrC motif.
257309006895	HMMPfam hit to PF01541, Endo/excinuclease amino terminal domain
257309006896	HMMSmart hit to SM00465, GIY-YIG type nucleases (URI domain)
257309006897	ProfileScan hit to PS50164, UvrC homology region 1.
257309006898	Protein of unknown function (DUF2581); Region: DUF2581; pfam10756
257309006899	2 probable transmembrane helices predicted for DIP1315 by TMHMM2.0
257309006900	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
257309006901	homopentamer interface [polypeptide binding]; other site
257309006902	active site
257309006903	HMMPfam hit to PF00885, 6,7-dimethyl-8-ribityllumazine synthase
257309006904	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
257309006905	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
257309006906	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
257309006907	dimerization interface [polypeptide binding]; other site
257309006908	active site
257309006909	HMMPfam hit to PF00925, GTP cyclohydrolase II
257309006910	HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate synthase
257309006911	BlastProDom hit to PD003034, PD003034
257309006912	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
257309006913	Lumazine binding domain; Region: Lum_binding; pfam00677
257309006914	Lumazine binding domain; Region: Lum_binding; pfam00677
257309006915	BlastProDom hit to PD004110, PD004110
257309006916	HMMPfam hit to PF00677, Lumazine binding domain
257309006917	HMMPfam hit to PF00677, Lumazine binding domain
257309006918	ScanRegExp hit to PS00693, Riboflavin synthase alpha chain family signature.
257309006919	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
257309006920	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
257309006921	catalytic motif [active]
257309006922	Zn binding site [ion binding]; other site
257309006923	RibD C-terminal domain; Region: RibD_C; pfam01872
257309006924	HMMPfam hit to PF01872, RibD C-terminal domain
257309006925	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase zinc-binding region
257309006926	ScanRegExp hit to PS00903, Cytidine and deoxycytidylate deaminases zinc-binding region signature.
257309006927	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
257309006928	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
257309006929	substrate binding site [chemical binding]; other site
257309006930	hexamer interface [polypeptide binding]; other site
257309006931	metal binding site [ion binding]; metal-binding site
257309006932	HMMPfam hit to PF00834, Ribulose-phosphate 3 epimerase
257309006933	ScanRegExp hit to PS01086, Ribulose-phosphate 3-epimerase signature 2.
257309006934	ScanRegExp hit to PS01085, Ribulose-phosphate 3-epimerase signature 1.
257309006935	16S rRNA methyltransferase B; Provisional; Region: PRK14902
257309006936	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
257309006937	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309006938	HMMPfam hit to PF01189, NOL1/NOP2/sun family
257309006939	HMMPfam hit to PF01029, NusB family
257309006940	BlastProDom hit to PD005242, PD005242
257309006941	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
257309006942	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
257309006943	putative active site [active]
257309006944	substrate binding site [chemical binding]; other site
257309006945	putative cosubstrate binding site; other site
257309006946	catalytic site [active]
257309006947	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
257309006948	substrate binding site [chemical binding]; other site
257309006949	HMMPfam hit to PF02911, Formyl transferase, C-terminal domain
257309006950	HMMPfam hit to PF00551, Formyl transferase
257309006951	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
257309006952	active site
257309006953	catalytic residues [active]
257309006954	metal binding site [ion binding]; metal-binding site
257309006955	HMMPfam hit to PF01327, Polypeptide deformylase
257309006956	BlastProDom hit to PD003844, PD003844
257309006957	primosome assembly protein PriA; Provisional; Region: PRK14873
257309006958	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006959	S-adenosylmethionine synthetase; Validated; Region: PRK05250
257309006960	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
257309006961	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
257309006962	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
257309006963	HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-terminal domain
257309006964	ScanRegExp hit to PS00377, S-adenosylmethionine synthetase signature 2.
257309006965	HMMPfam hit to PF02772, S-adenosylmethionine synthetase, central domain
257309006966	ScanRegExp hit to PS00376, S-adenosylmethionine synthetase signature 1.
257309006967	HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-terminal domain
257309006968	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
257309006969	Flavoprotein; Region: Flavoprotein; pfam02441
257309006970	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
257309006971	HMMPfam hit to PF02441, Flavoprotein
257309006972	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
257309006973	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
257309006974	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
257309006975	catalytic site [active]
257309006976	G-X2-G-X-G-K; other site
257309006977	HMMSmart hit to SM00072, Guanylate kinase homologues.
257309006978	ProfileScan hit to PS50052, Guanylate kinase domain profile.
257309006979	HMMPfam hit to PF00625, Guanylate kinase
257309006980	ScanRegExp hit to PS00856, Guanylate kinase signature.
257309006981	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309006982	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
257309006983	active site
257309006984	dimer interface [polypeptide binding]; other site
257309006985	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase
257309006986	ScanRegExp hit to PS00156, Orotidine 5'-phosphate decarboxylase active site.
257309006987	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
257309006988	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
257309006989	ATP-grasp domain; Region: ATP-grasp_4; cl17255
257309006990	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
257309006991	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
257309006992	ATP-grasp domain; Region: ATP-grasp_4; cl17255
257309006993	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
257309006994	IMP binding site; other site
257309006995	dimer interface [polypeptide binding]; other site
257309006996	HMMPfam hit to PF02142, MGS-like domain
257309006997	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP binding domain
257309006998	ScanRegExp hit to PS00867, Carbamoyl-phosphate synthase subdomain signature 2.
257309006999	ScanRegExp hit to PS00866, Carbamoyl-phosphate synthase subdomain signature 1.
257309007000	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain, N-terminal domain
257309007001	HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large chain, oligomerisation domain
257309007002	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007003	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP binding domain
257309007004	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007005	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007006	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007007	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007008	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain, N-terminal domain
257309007009	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007010	FPrintScan hit to PR00098, Carbamoyl-phosphate synthase CPSase domain signature
257309007011	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
257309007012	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
257309007013	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
257309007014	catalytic site [active]
257309007015	subunit interface [polypeptide binding]; other site
257309007016	HMMPfam hit to PF00117, Glutamine amidotransferase class-I
257309007017	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309007018	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309007019	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309007020	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309007021	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature; ScanRegExp hit to PS00442, Glutamine amidotransferases class-I active site.
257309007022	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309007023	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309007024	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309007025	HMMPfam hit to PF00988, Carbamoyl-phosphate synthase small chain, CPSase domain
257309007026	dihydroorotase; Validated; Region: pyrC; PRK09357
257309007027	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
257309007028	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
257309007029	active site
257309007030	HMMPfam hit to PF00744, Dihydroorotase-like
257309007031	ScanRegExp hit to PS00483, Dihydroorotase signature 2.
257309007032	ScanRegExp hit to PS00482, Dihydroorotase signature 1.
257309007033	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
257309007034	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
257309007035	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
257309007036	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309007037	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309007038	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309007039	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309007040	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309007041	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309007042	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309007043	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
257309007044	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309007045	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309007046	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309007047	FPrintScan hit to PR00100, Aspartate/ornithine carbamoyltransferase superfamily signature
257309007048	FPrintScan hit to PR00101, Aspartate carbamoyltransferase signature
257309007049	FPrintScan hit to PR00102, Ornithine carbamoyltransferase signature
257309007050	ScanRegExp hit to PS00097, Aspartate and ornithine carbamoyltransferases signature.
257309007051	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
257309007052	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309007053	active site
257309007054	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309007055	hydrophobic ligand binding site; other site
257309007056	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
257309007057	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
257309007058	TIGR01777 family protein; Region: yfcH
257309007059	NAD(P) binding site [chemical binding]; other site
257309007060	active site
257309007061	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
257309007062	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
257309007063	HMMPfam hit to PF01029, NusB family
257309007064	BlastProDom hit to PD005242, PD005242
257309007065	elongation factor P; Validated; Region: PRK00529
257309007066	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
257309007067	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
257309007068	RNA binding site [nucleotide binding]; other site
257309007069	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
257309007070	RNA binding site [nucleotide binding]; other site
257309007071	HMMPfam hit to PF01132, Elongation factor P (EF-P)
257309007072	ScanRegExp hit to PS01275, Elongation factor P signature.
257309007073	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
257309007074	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
257309007075	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
257309007076	active site
257309007077	HMMPfam hit to PF00557, metallopeptidase M24
257309007078	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309007079	ScanRegExp hit to PS00491, Aminopeptidase P and proline dipeptidase signature.
257309007080	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309007081	Dehydroquinase class II; Region: DHquinase_II; pfam01220
257309007082	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
257309007083	trimer interface [polypeptide binding]; other site
257309007084	active site
257309007085	dimer interface [polypeptide binding]; other site
257309007086	HMMPfam hit to PF01220, Dehydroquinase class II
257309007087	ScanRegExp hit to PS01029, Dehydroquinase class II signature.
257309007088	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
257309007089	active site
257309007090	dimer interface [polypeptide binding]; other site
257309007091	metal binding site [ion binding]; metal-binding site
257309007092	HMMPfam hit to PF01761, 3-dehydroquinate synthase
257309007093	shikimate kinase; Reviewed; Region: aroK; PRK00131
257309007094	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
257309007095	ADP binding site [chemical binding]; other site
257309007096	magnesium binding site [ion binding]; other site
257309007097	putative shikimate binding site; other site
257309007098	HMMPfam hit to PF01202, Shikimate kinase
257309007099	FPrintScan hit to PR01100, Shikimate kinase signature
257309007100	FPrintScan hit to PR01100, Shikimate kinase signature
257309007101	ScanRegExp hit to PS01128, Shikimate kinase signature.
257309007102	FPrintScan hit to PR01100, Shikimate kinase signature
257309007103	FPrintScan hit to PR01100, Shikimate kinase signature
257309007104	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309007105	FPrintScan hit to PR01100, Shikimate kinase signature
257309007106	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007107	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
257309007108	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
257309007109	Tetramer interface [polypeptide binding]; other site
257309007110	active site
257309007111	FMN-binding site [chemical binding]; other site
257309007112	HMMPfam hit to PF01264, Chorismate synthase
257309007113	ScanRegExp hit to PS00789, Chorismate synthase signature 3.
257309007114	BlastProDom hit to PD002941, PD002941
257309007115	ScanRegExp hit to PS00788, Chorismate synthase signature 2.
257309007116	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
257309007117	4 probable transmembrane helices predicted for DIP1346 by TMHMM2.0
257309007118	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
257309007119	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
257309007120	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
257309007121	shikimate binding site; other site
257309007122	NAD(P) binding site [chemical binding]; other site
257309007123	HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase
257309007124	ProfileScan hit to PS50204, UBA/THIF-type NAD binding fold.
257309007125	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
257309007126	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
257309007127	dimerization interface [polypeptide binding]; other site
257309007128	HMMPfam hit to PF02618, Uncharacterized BCR, YceG family COG1559
257309007129	1 probable transmembrane helix predicted for DIP1348 by TMHMM2.0
257309007130	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
257309007131	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
257309007132	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
257309007133	motif 1; other site
257309007134	active site
257309007135	motif 2; other site
257309007136	motif 3; other site
257309007137	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
257309007138	DHHA1 domain; Region: DHHA1; pfam02272
257309007139	HMMPfam hit to PF02272, DHHA1 domain
257309007140	HMMPfam hit to PF01411, tRNA synthetases class II (A)
257309007141	FPrintScan hit to PR00980, Alanyl-tRNA synthetase signature
257309007142	FPrintScan hit to PR00980, Alanyl-tRNA synthetase signature
257309007143	FPrintScan hit to PR00980, Alanyl-tRNA synthetase signature
257309007144	FPrintScan hit to PR00980, Alanyl-tRNA synthetase signature
257309007145	FPrintScan hit to PR00980, Alanyl-tRNA synthetase signature
257309007146	recombination factor protein RarA; Reviewed; Region: PRK13342
257309007147	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309007148	Walker A motif; other site
257309007149	ATP binding site [chemical binding]; other site
257309007150	Walker B motif; other site
257309007151	arginine finger; other site
257309007152	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
257309007153	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007154	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309007155	ProfileScan hit to PS50150, Replication factor C conserved domain.
257309007156	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309007157	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007158	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
257309007159	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
257309007160	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
257309007161	dimer interface [polypeptide binding]; other site
257309007162	anticodon binding site; other site
257309007163	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
257309007164	homodimer interface [polypeptide binding]; other site
257309007165	motif 1; other site
257309007166	active site
257309007167	motif 2; other site
257309007168	GAD domain; Region: GAD; pfam02938
257309007169	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
257309007170	active site
257309007171	motif 3; other site
257309007172	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N)
257309007173	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309007174	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309007175	HMMPfam hit to PF02938, GAD domain
257309007176	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N)
257309007177	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature; ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309007178	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309007179	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309007180	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309007181	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309007182	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain
257309007183	Predicted metalloprotease [General function prediction only]; Region: COG2321
257309007184	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
257309007185	1 probable transmembrane helix predicted for DIP1354 by TMHMM2.0
257309007186	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309007187	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309007188	ATP binding site [chemical binding]; other site
257309007189	putative Mg++ binding site [ion binding]; other site
257309007190	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309007191	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
257309007192	nucleotide binding region [chemical binding]; other site
257309007193	ATP-binding site [chemical binding]; other site
257309007194	HMMPfam hit to PF00271, Helicase conserved C-terminal domain
257309007195	HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309007196	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309007197	HMMPfam hit to PF00176, SNF2 and others N-terminal domain
257309007198	ProfileScan hit to PS50120, Helix-hairpin-helix motif.
257309007199	HMMPfam hit to PF00633, Helix-hairpin-helix motif.
257309007200	Predicted membrane protein [Function unknown]; Region: COG1511
257309007201	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
257309007202	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
257309007203	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
257309007204	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
257309007205	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
257309007206	6 probable transmembrane helices predicted for DIP1356 by TMHMM2.0
257309007207	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007208	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309007209	Q-loop/lid; other site
257309007210	ABC transporter signature motif; other site
257309007211	Walker B; other site
257309007212	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309007213	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309007214	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309007215	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309007216	Predicted helix-turn-helix motif with score 1291 (+3.58 SD) at aa 27-48, sequence MTVESVAERAKVGIATLYRNFP
257309007217	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309007218	1 probable transmembrane helix predicted for DIP1358 by TMHMM2.0
257309007219	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
257309007220	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
257309007221	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
257309007222	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
257309007223	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
257309007224	dimer interface [polypeptide binding]; other site
257309007225	motif 1; other site
257309007226	active site
257309007227	motif 2; other site
257309007228	motif 3; other site
257309007229	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
257309007230	anticodon binding site; other site
257309007231	HMMPfam hit to PF03129
257309007232	HMMPfam hit to PF00587, tRNA synthetase class II (G, H, P, S and T)
257309007233	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
257309007234	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily
257309007235	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
257309007236	dimer interface [polypeptide binding]; other site
257309007237	catalytic triad [active]
257309007238	peroxidatic and resolving cysteines [active]
257309007239	HMMPfam hit to PF00578, AhpC/TSA family
257309007240	ScanRegExp hit to PS01265, Tpx family signature.
257309007241	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
257309007242	active site
257309007243	1 probable transmembrane helix predicted for DIP1363 by TMHMM2.0
257309007244	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-trans isomerase
257309007245	ProfileScan hit to PS50072, Cyclophilin-type peptidyl-prolyl cis-trans isomerase profile.
257309007246	1 probable transmembrane helix predicted for DIP1364 by TMHMM2.0
257309007247	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
257309007248	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
257309007249	HTH-like domain; Region: HTH_21; pfam13276
257309007250	Integrase core domain; Region: rve; pfam00665
257309007251	Integrase core domain; Region: rve_2; pfam13333
257309007252	1 probable transmembrane helix predicted for DIP1366 by TMHMM2.0
257309007253	HMMPfam hit to PF00665, Integrase core domain
257309007254	Pseudogene/partial. Similar to parts of Corynebacterium jeikeium transposase SWALL:Q9AG97 (EMBL:AF338705) (392 aa) fasta scores: E(): 7e-11, 45.91% id in 98 aa. Note: Lacks stop codon; transposase (partial)
257309007255	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
257309007256	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
257309007257	Zn2+ binding site [ion binding]; other site
257309007258	Mg2+ binding site [ion binding]; other site
257309007259	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
257309007260	synthetase active site [active]
257309007261	NTP binding site [chemical binding]; other site
257309007262	metal binding site [ion binding]; metal-binding site
257309007263	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
257309007264	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
257309007265	HMMPfam hit to PF01842, ACT domain
257309007266	HMMPfam hit to PF02824, TGS domain
257309007267	HMMSmart hit to SM00471, Metal dependent phosphohydrolases with conserved 'HD' motif.
257309007268	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309007269	active site
257309007270	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309007271	ScanRegExp hit to PS00103, Purine/pyrimidine phosphoribosyl transferases signature.
257309007272	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
257309007273	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
257309007274	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
257309007275	Protein export membrane protein; Region: SecD_SecF; cl14618
257309007276	HMMPfam hit to PF02355, Protein export membrane protein
257309007277	6 probable transmembrane helices predicted for DIP1371 by TMHMM2.0
257309007278	Preprotein translocase subunit SecD [Intracellular trafficking and secretion]; Region: SecD; COG0342
257309007279	Protein export membrane protein; Region: SecD_SecF; cl14618
257309007280	HMMPfam hit to PF02355, Protein export membrane protein
257309007281	6 probable transmembrane helices predicted for DIP1372 by TMHMM2.0
257309007282	Preprotein translocase subunit; Region: YajC; pfam02699
257309007283	HMMPfam hit to PF02699, Uncharacterized secreted proteins, YajC family COG1862
257309007284	1 probable transmembrane helix predicted for DIP1374 by TMHMM2.0
257309007285	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
257309007286	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309007287	Walker A motif; other site
257309007288	ATP binding site [chemical binding]; other site
257309007289	Walker B motif; other site
257309007290	arginine finger; other site
257309007291	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
257309007292	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309007293	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309007294	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007295	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
257309007296	RuvA N terminal domain; Region: RuvA_N; pfam01330
257309007297	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
257309007298	BlastProDom hit to PD006268, PD006268
257309007299	HMMPfam hit to PF02904, RuvA central domain II
257309007300	HMMPfam hit to PF01330, RuvA N terminal domain
257309007301	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
257309007302	active site
257309007303	putative DNA-binding cleft [nucleotide binding]; other site
257309007304	dimer interface [polypeptide binding]; other site
257309007305	BlastProDom hit to PD008333, PD008333
257309007306	HMMPfam hit to PF02075, Crossover junction endodeoxyribonuclease RuvC
257309007307	FPrintScan hit to PR00696, Crossover junction endodeoxyribonuclease RUVC signature
257309007308	FPrintScan hit to PR00696, Crossover junction endodeoxyribonuclease RUVC signature
257309007309	FPrintScan hit to PR00696, Crossover junction endodeoxyribonuclease RUVC signature
257309007310	FPrintScan hit to PR00696, Crossover junction endodeoxyribonuclease RUVC signature
257309007311	FPrintScan hit to PR00696, Crossover junction endodeoxyribonuclease RUVC signature
257309007312	hypothetical protein; Validated; Region: PRK00110
257309007313	HMMPfam hit to PF01709, Domain of unknown function DUF28
257309007314	BlastProDom hit to PD004323, PD004323
257309007315	Acyl-CoA thioesterase [Lipid metabolism]; Region: TesB; COG1946
257309007316	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
257309007317	active site
257309007318	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
257309007319	catalytic triad [active]
257309007320	dimer interface [polypeptide binding]; other site
257309007321	HMMPfam hit to PF02551, Acyl-CoA thioesterase
257309007322	9 probable transmembrane helices predicted for DIP1380 by TMHMM2.0
257309007323	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309007324	6-carboxyhexanoate--CoA ligase; Region: BioW; pfam03744
257309007325	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
257309007326	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
257309007327	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
257309007328	catalytic residue [active]
257309007329	HMMPfam hit to PF00155, Aminotransferase class I and II
257309007330	1 probable transmembrane helix predicted for DIP1383 by TMHMM2.0
257309007331	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
257309007332	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
257309007333	HMMPfam hit to PF00534, Glycosyl transferases group 1
257309007334	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
257309007335	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
257309007336	putative acyl-acceptor binding pocket; other site
257309007337	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
257309007338	HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase
257309007339	4 probable transmembrane helices predicted for DIP1386 by TMHMM2.0
257309007340	ProfileScan hit to PS50291, CDP-alcohol phosphatidyltransferases profile
257309007341	ScanRegExp hit to PS00379, CDP-alcohol phosphatidyltransferases signature.
257309007342	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
257309007343	nucleotide binding site/active site [active]
257309007344	HIT family signature motif; other site
257309007345	catalytic residue [active]
257309007346	HMMPfam hit to PF01230, HIT family
257309007347	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
257309007348	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
257309007349	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
257309007350	active site
257309007351	dimer interface [polypeptide binding]; other site
257309007352	motif 1; other site
257309007353	motif 2; other site
257309007354	motif 3; other site
257309007355	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
257309007356	anticodon binding site; other site
257309007357	HMMPfam hit to PF03129
257309007358	FPrintScan hit to PR01047, Threonyl-tRNA synthetase signature
257309007359	ScanRegExp hit to PS00339, Aminoacyl-transfer RNA synthetases class-II signature 2.
257309007360	FPrintScan hit to PR01047, Threonyl-tRNA synthetase signature
257309007361	FPrintScan hit to PR01047, Threonyl-tRNA synthetase signature
257309007362	HMMPfam hit to PF00587, tRNA synthetase class II (G, H, P, S and T)
257309007363	FPrintScan hit to PR01047, Threonyl-tRNA synthetase signature
257309007364	ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309007365	FPrintScan hit to PR01047, Threonyl-tRNA synthetase signature
257309007366	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
257309007367	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
257309007368	Potential twin-arginine recognition motif RRGFLT
257309007369	Protein of unknown function (DUF461); Region: DUF461; pfam04314
257309007370	CopC domain; Region: CopC; cl01012
257309007371	1 probable transmembrane helix predicted for DIP1391 by TMHMM2.0
257309007372	hypothetical protein; Provisional; Region: PRK14059
257309007373	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
257309007374	HMMPfam hit to PF01872, RibD C-terminal domain
257309007375	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
257309007376	SelR domain; Region: SelR; pfam01641
257309007377	BlastProDom hit to PD004057, PD004057
257309007378	HMMPfam hit to PF01641, Domain of unknown function DUF25
257309007379	Predicted heme peroxidase involved in anaerobic stress response [General function prediction only]; Region: ywfI; COG3253
257309007380	Protein of unknown function (DUF3000); Region: DUF3000; pfam11452
257309007381	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
257309007382	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
257309007383	catalytic site [active]
257309007384	putative active site [active]
257309007385	putative substrate binding site [chemical binding]; other site
257309007386	HRDC domain; Region: HRDC; pfam00570
257309007387	HMMPfam hit to PF01612, 3'-5' exonuclease
257309007388	HMMSmart hit to SM00474, 3'-5' exonuclease
257309007389	HMMPfam hit to PF00570, HRDC domain
257309007390	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
257309007391	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
257309007392	TPP-binding site; other site
257309007393	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
257309007394	PYR/PP interface [polypeptide binding]; other site
257309007395	dimer interface [polypeptide binding]; other site
257309007396	TPP binding site [chemical binding]; other site
257309007397	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
257309007398	HMMPfam hit to PF02780, Transketolase, C-terminal domain
257309007399	HMMPfam hit to PF02779, Transketolase, pyridine binding domain
257309007400	ScanRegExp hit to PS00802, Transketolase signature 2.
257309007401	ScanRegExp hit to PS00801, Transketolase signature 1.
257309007402	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
257309007403	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
257309007404	HMMPfam hit to PF01938, TRAM domain
257309007405	Protein of unknown function (DUF3710); Region: DUF3710; pfam12502
257309007406	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
257309007407	trimer interface [polypeptide binding]; other site
257309007408	active site
257309007409	HMMPfam hit to PF00692, dUTPase
257309007410	BlastProDom hit to PD000946, PD000946
257309007411	Protein of unknown function (DUF3093); Region: DUF3093; pfam11292
257309007412	2 probable transmembrane helices predicted for DIP1401 by TMHMM2.0
257309007413	Domain of unknown function (DUF4193); Region: DUF4193; pfam13834
257309007414	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
257309007415	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
257309007416	active site
257309007417	dimerization interface [polypeptide binding]; other site
257309007418	HMMPfam hit to PF00459, Inositol monophosphatase
257309007419	FPrintScan hit to PR00378, Inositol phosphatase signature
257309007420	ScanRegExp hit to PS00630, Inositol monophosphatase signature 2.
257309007421	FPrintScan hit to PR00378, Inositol phosphatase signature
257309007422	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309007423	FPrintScan hit to PR00378, Inositol phosphatase signature
257309007424	ScanRegExp hit to PS00629, Inositol monophosphatase signature 1.
257309007425	FPrintScan hit to PR00378, Inositol phosphatase signature
257309007426	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
257309007427	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
257309007428	nucleotide binding site [chemical binding]; other site
257309007429	1 probable transmembrane helix predicted for DIP1405 by TMHMM2.0
257309007430	RNA polymerase sigma factor SigB; Reviewed; Region: PRK07921
257309007431	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
257309007432	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309007433	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
257309007434	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309007435	DNA binding residues [nucleotide binding]
257309007436	ProfileScan hit to PS50318, Lysine-rich region.
257309007437	ProfileScan hit to PS50312, Aspartic acid-rich region.
257309007438	HMMPfam hit to PF00140, Sigma-70 factor
257309007439	ScanRegExp hit to PS00867, Carbamoyl-phosphate synthase subdomain signature 2.
257309007440	ScanRegExp hit to PS00030, Eukaryotic RNA Recognition Motif (RRM) RNP-1 region signature.
257309007441	FPrintScan hit to PR00046, Major sigma-70 factor signature; ScanRegExp hit to PS00715, Sigma-70 factors family signature 1.
257309007442	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007443	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007444	Predicted helix-turn-helix motif with score 1603 (+4.65 SD) at aa 461-482, sequence RTLDEIGQVYGVTRERIRQIES
257309007445	ScanRegExp hit to PS00716, Sigma-70 factors family signature 2.
257309007446	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007447	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007448	3 probable transmembrane helices predicted for DIP1407 by TMHMM2.0
257309007449	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
257309007450	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309007451	ATP binding site [chemical binding]; other site
257309007452	putative Mg++ binding site [ion binding]; other site
257309007453	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309007454	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007455	Protein of unknown function (DUF3039); Region: DUF3039; pfam11238
257309007456	Protein of unknown function (DUF3099); Region: DUF3099; pfam11298
257309007457	2 probable transmembrane helices predicted for DIP1410 by TMHMM2.0
257309007458	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
257309007459	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309007460	S-adenosylmethionine binding site [chemical binding]; other site
257309007461	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309007462	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309007463	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
257309007464	putative active site [active]
257309007465	dimerization interface [polypeptide binding]; other site
257309007466	putative tRNAtyr binding site [nucleotide binding]; other site
257309007467	HMMPfam hit to PF02580, Uncharacterized ACR, COG1490
257309007468	ScanRegExp hit to PS00678, Trp-Asp (WD) repeats signature.
257309007469	RNA polymerase sigma factor SigB; Reviewed; Region: PRK07921
257309007470	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
257309007471	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309007472	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
257309007473	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309007474	DNA binding residues [nucleotide binding]
257309007475	HMMPfam hit to PF00140, Sigma-70 factor
257309007476	ScanRegExp hit to PS00867, Carbamoyl-phosphate synthase subdomain signature 2.
257309007477	FPrintScan hit to PR00046, Major sigma-70 factor signature; ScanRegExp hit to PS00715, Sigma-70 factors family signature 1.
257309007478	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007479	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007480	Predicted helix-turn-helix motif with score 1921 (+5.73 SD) at aa 288-309, sequence RTLDQIGRQFGLSRERVRQIER
257309007481	ScanRegExp hit to PS00716, Sigma-70 factors family signature 2.
257309007482	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007483	FPrintScan hit to PR00046, Major sigma-70 factor signature
257309007484	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
257309007485	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
257309007486	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
257309007487	FeoA domain; Region: FeoA; cl00838
257309007488	HMMPfam hit to PF01325, Iron dependent repressor, N-terminal DNA binding domain
257309007489	HMMSmart hit to SM00529, Helix-turn-helix diphteria tox regulatory element
257309007490	HMMPfam hit to PF02742, Iron dependent repressor, metal binding and dimerisation domain
257309007491	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
257309007492	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
257309007493	NAD binding site [chemical binding]; other site
257309007494	homodimer interface [polypeptide binding]; other site
257309007495	active site
257309007496	substrate binding site [chemical binding]; other site
257309007497	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase
257309007498	Domain of unknown function (DUF4192); Region: DUF4192; pfam13830
257309007499	PAC2 family; Region: PAC2; pfam09754
257309007500	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309007501	ATP binding site [chemical binding]; other site
257309007502	putative Mg++ binding site [ion binding]; other site
257309007503	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309007504	nucleotide binding region [chemical binding]; other site
257309007505	ATP-binding site [chemical binding]; other site
257309007506	Domain of unknown function (DUF3516); Region: DUF3516; pfam12029
257309007507	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309007508	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309007509	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309007510	alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777
257309007511	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
257309007512	HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase
257309007513	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
257309007514	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
257309007515	dimer interface [polypeptide binding]; other site
257309007516	decamer (pentamer of dimers) interface [polypeptide binding]; other site
257309007517	catalytic triad [active]
257309007518	peroxidatic and resolving cysteines [active]
257309007519	HMMPfam hit to PF00578, AhpC/TSA family
257309007520	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
257309007521	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
257309007522	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
257309007523	dimerization interface [polypeptide binding]; other site
257309007524	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protein, lysR family
257309007525	Predicted helix-turn-helix motif with score 1206 (+3.29 SD) at aa 23-44, sequence KHFGTAAAKLSISQPSLSQALA
257309007526	ScanRegExp hit to PS00044, Bacterial regulatory proteins, lysR family signature.
257309007527	FPrintScan hit to PR00039, LysR bacterial regulatory protein HTH signature
257309007528	FPrintScan hit to PR00039, LysR bacterial regulatory protein HTH signature
257309007529	FPrintScan hit to PR00039, LysR bacterial regulatory protein HTH signature
257309007530	5 probable transmembrane helices predicted for DIP1422 by TMHMM2.0
257309007531	ATP-dependent helicase HrpA; Region: DEAH_box_HrpA; TIGR01967
257309007532	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309007533	ATP binding site [chemical binding]; other site
257309007534	putative Mg++ binding site [ion binding]; other site
257309007535	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
257309007536	nucleotide binding region [chemical binding]; other site
257309007537	ATP-binding site [chemical binding]; other site
257309007538	Helicase associated domain (HA2); Region: HA2; pfam04408
257309007539	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
257309007540	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
257309007541	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309007542	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007543	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309007544	HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309007545	HMMPfam hit to PF00271, Helicase conserved C-terminal domain
257309007546	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
257309007547	ATP cone domain; Region: ATP-cone; pfam03477
257309007548	HMMPfam hit to PF02644, Uncharacterized BCR, COG1327
257309007549	1 probable transmembrane helix predicted for DIP1425 by TMHMM2.0
257309007550	LexA repressor; Validated; Region: PRK00215
257309007551	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
257309007552	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
257309007553	Catalytic site [active]
257309007554	HMMPfam hit to PF01726, LexA DNA binding domain
257309007555	HMMPfam hit to PF00717, Peptidase S24
257309007556	FPrintScan hit to PR00726, Repressor LexA serine protease (S24) family signature
257309007557	FPrintScan hit to PR00726, Repressor LexA serine protease (S24) family signature
257309007558	FPrintScan hit to PR00726, Repressor LexA serine protease (S24) family signature
257309007559	PTS system
257309007560	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
257309007561	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
257309007562	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
257309007563	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family
257309007564	HMMSmart hit to SM00420, helix_turn_helix, Deoxyribose operon repressor, DNA-binding
257309007565	Predicted helix-turn-helix motif with score 1468 (+4.19 SD) at aa 20-41, sequence VNVTELAARFDVTAETIRRDLA
257309007566	FPrintScan hit to PR00037, LacR bacterial regulatory protein HTH signature
257309007567	FPrintScan hit to PR00037, LacR bacterial regulatory protein HTH signature
257309007568	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
257309007569	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
257309007570	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
257309007571	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
257309007572	HMMPfam hit to PF02896, PEP-utilizing enzyme, TIM barrel domain
257309007573	BlastProDom hit to PD000940, PD000940
257309007574	ScanRegExp hit to PS00742, PEP-utilizing enzymes signature 2.
257309007575	HMMPfam hit to PF00391, PEP-utilizing enzyme, mobile domain
257309007576	ScanRegExp hit to PS00370, PEP-utilizing enzymes phosphorylation site signature.
257309007577	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
257309007578	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309007579	DNA-binding site [nucleotide binding]; DNA binding site
257309007580	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
257309007581	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family
257309007582	HMMSmart hit to SM00420, helix_turn_helix, Deoxyribose operon repressor, DNA-binding
257309007583	Predicted helix-turn-helix motif with score 1839 (+5.45 SD) at aa 24-45, sequence SSVTQLAQQFDVTPETIRRDLK
257309007584	FPrintScan hit to PR00037, LacR bacterial regulatory protein HTH signature
257309007585	FPrintScan hit to PR00037, LacR bacterial regulatory protein HTH signature
257309007586	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
257309007587	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
257309007588	putative substrate binding site [chemical binding]; other site
257309007589	putative ATP binding site [chemical binding]; other site
257309007590	HMMPfam hit to PF00294, pfkB family carbohydrate kinase
257309007591	FPrintScan hit to PR00990, Ribokinase signature
257309007592	FPrintScan hit to PR00990, Ribokinase signature
257309007593	ScanRegExp hit to PS00584, pfkB family of carbohydrate kinases signature 2.
257309007594	Pseudogene. Similar to Escherichia coli PTS system, fructose-specific IIBC component FruA or PtsF or B2167 SW:PTFB_ECOLI (P20966) (563 aa) fasta scores: E(): 2.4e-58, 43.86% id in 481 aa, and to Rhodobacter capsulatus PTS system, fructose-specific IIBC component FruA SW:PTFB_RHOCA (P23387) (578 aa) fasta scores: E(): 2.5e-57, 38.86% id in 584 aa. Presents multiple frameshifts at residues 114, 276 and 374; fructose-specific IIBC (PTS system) (pseudogene)
257309007595	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
257309007596	BlastProDom hit to PD001689, PD001689
257309007597	HMMPfam hit to PF02379, PTS system, Fructose specific IIB subunit
257309007598	1 probable transmembrane helix predicted for DIP1434 by TMHMM2.0; 3 probable transmembrane helices predicted for DIP1433 by TMHMM2.0; 2 probable transmembrane helices predicted for DIP1432 by TMHMM2.0; Signal peptide predicted for DIP1434 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.737 between residues 25 and 26
257309007599	HMMPfam hit to PF02378, Phosphotransferase system, EIIC
257309007600	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
257309007601	dimerization domain swap beta strand [polypeptide binding]; other site
257309007602	regulatory protein interface [polypeptide binding]; other site
257309007603	active site
257309007604	regulatory phosphorylation site [posttranslational modification]; other site
257309007605	HMMPfam hit to PF00381, PTS HPr component phosphorylation site
257309007606	FPrintScan hit to PR00107, Phosphocarrier protein signature
257309007607	ScanRegExp hit to PS00369, PTS HPR component histidine phosphorylation site signature.
257309007608	FPrintScan hit to PR00107, Phosphocarrier protein signature
257309007609	FPrintScan hit to PR00107, Phosphocarrier protein signature
257309007610	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
257309007611	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
257309007612	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
257309007613	HMMPfam hit to PF00296, Luciferase-like monooxygenase
257309007614	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
257309007615	LLM-partnered FMN reductase, CE1759 family; Region: LLM_duo_CE1759; TIGR04037
257309007616	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
257309007617	11 probable transmembrane helices predicted for DIP1438 by TMHMM2.0
257309007618	HMMPfam hit to PF00860, Xanthine/uracil permeases family
257309007619	GTPases [General function prediction only]; Region: HflX; COG2262
257309007620	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
257309007621	HflX GTPase family; Region: HflX; cd01878
257309007622	G1 box; other site
257309007623	GTP/Mg2+ binding site [chemical binding]; other site
257309007624	Switch I region; other site
257309007625	G2 box; other site
257309007626	G3 box; other site
257309007627	Switch II region; other site
257309007628	G4 box; other site
257309007629	G5 box; other site
257309007630	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309007631	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309007632	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007633	ProfileScan hit to PS50315, Glycine-rich region.
257309007634	1 probable transmembrane helix predicted for DIP1441 by TMHMM2.0
257309007635	Predicted helix-turn-helix motif with score 1009 (+2.62 SD) at aa 138-159, sequence LNTSQLEKLLDITDQRASQLQQ
257309007636	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
257309007637	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
257309007638	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
257309007639	HMMPfam hit to PF01678, Diaminopimelate epimerase
257309007640	ScanRegExp hit to PS01326, Diaminopimelate epimerase signature.
257309007641	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
257309007642	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
257309007643	HMMPfam hit to PF01715, IPP transferase
257309007644	BlastProDom hit to PD004674, PD004674
257309007645	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007646	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
257309007647	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
257309007648	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
257309007649	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
257309007650	4 probable transmembrane helices predicted for DIP1447 by TMHMM2.0
257309007651	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14326
257309007652	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
257309007653	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309007654	FeS/SAM binding site; other site
257309007655	ScanRegExp hit to PS01278, Uncharacterized protein family UPF0004 signature.
257309007656	HMMPfam hit to PF00919, Uncharacterized protein family UPF0004
257309007657	recombination regulator RecX; Reviewed; Region: recX; PRK00117
257309007658	HMMPfam hit to PF02631, RecX family
257309007659	recombinase A; Provisional; Region: recA; PRK09354
257309007660	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
257309007661	hexamer interface [polypeptide binding]; other site
257309007662	Walker A motif; other site
257309007663	ATP binding site [chemical binding]; other site
257309007664	Walker B motif; other site
257309007665	ProfileScan hit to PS50312, Aspartic acid-rich region.
257309007666	HMMPfam hit to PF00154, recA bacterial DNA recombination protein
257309007667	FPrintScan hit to PR00142, RecA protein signature
257309007668	ProfileScan hit to PS50163, RecA family profile 2.
257309007669	FPrintScan hit to PR00142, RecA protein signature
257309007670	FPrintScan hit to PR00142, RecA protein signature
257309007671	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309007672	ScanRegExp hit to PS00321, recA signature.
257309007673	ProfileScan hit to PS50162, RecA family profile 1.
257309007674	FPrintScan hit to PR00142, RecA protein signature
257309007675	FPrintScan hit to PR00142, RecA protein signature
257309007676	FPrintScan hit to PR00142, RecA protein signature
257309007677	FPrintScan hit to PR00142, RecA protein signature
257309007678	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007679	FPrintScan hit to PR00142, RecA protein signature
257309007680	Protein of unknown function (DUF3046); Region: DUF3046; pfam11248
257309007681	BioY family; Region: BioY; pfam02632
257309007682	6 probable transmembrane helices predicted for DIP1452 by TMHMM2.0
257309007683	HMMPfam hit to PF02632, BioY family
257309007684	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
257309007685	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
257309007686	Walker A/P-loop; other site
257309007687	ATP binding site [chemical binding]; other site
257309007688	Q-loop/lid; other site
257309007689	ABC transporter signature motif; other site
257309007690	Walker B; other site
257309007691	D-loop; other site
257309007692	H-loop/switch region; other site
257309007693	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309007694	HMMPfam hit to PF00005, ABC transporter
257309007695	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309007696	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007697	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309007698	ScanRegExp hit to PS00211, ABC transporters family signature.
257309007699	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
257309007700	HMMPfam hit to PF02361, Cobalt transport protein
257309007701	3 probable transmembrane helices predicted for DIP1454 by TMHMM2.0
257309007702	ScanRegExp hit to PS00659, Glycosyl hydrolases family 5 signature.
257309007703	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
257309007704	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
257309007705	sequence-specific DNA binding site [nucleotide binding]; other site
257309007706	salt bridge; other site
257309007707	HMMSmart hit to SM00530, Helix-turn-helix XRE-family like proteins, DNA-binding
257309007708	HMMPfam hit to PF01381, Helix-turn-helix
257309007709	Predicted helix-turn-helix motif with score 1339 (+3.75 SD) at aa 43-64, sequence ITLRELAETSRVSPGYLSELER
257309007710	Competence-damaged protein; Region: CinA; pfam02464
257309007711	HMMPfam hit to PF02464, Competence-damaged protein
257309007712	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
257309007713	HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase
257309007714	4 probable transmembrane helices predicted for DIP1458 by TMHMM2.0
257309007715	ProfileScan hit to PS50291, CDP-alcohol phosphatidyltransferases profile
257309007716	ScanRegExp hit to PS00379, CDP-alcohol phosphatidyltransferases signature.
257309007717	YCII-related domain; Region: YCII; cl00999
257309007718	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
257309007719	9 probable transmembrane helices predicted for DIP1460 by TMHMM2.0
257309007720	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
257309007721	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
257309007722	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
257309007723	HMMPfam hit to PF01580, FtsK/SpoIIIE family
257309007724	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007725	4 probable transmembrane helices predicted for DIP1461 by TMHMM2.0
257309007726	ProfileScan hit to PS50324, Serine-rich region.
257309007727	TIGR03085 family protein; Region: TIGR03085
257309007728	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
257309007729	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
257309007730	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
257309007731	HMMPfam hit to PF02147, Uncharacterized protein family UPF0036
257309007732	ScanRegExp hit to PS01292, Uncharacterized protein family UPF0036 signature.
257309007733	ScanRegExp hit to PS00595, Aminotransferases class-V pyridoxal-phosphate attachment site.
257309007734	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily
257309007735	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
257309007736	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
257309007737	dimer interface [polypeptide binding]; other site
257309007738	active site
257309007739	catalytic residue [active]
257309007740	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase
257309007741	BlastProDom hit to PD001859, PD001859
257309007742	ScanRegExp hit to PS00666, Dihydrodipicolinate synthetase signature 2.
257309007743	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309007744	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309007745	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309007746	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309007747	ScanRegExp hit to PS00665, Dihydrodipicolinate synthetase signature 1.
257309007748	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
257309007749	HMMPfam hit to PF02511, Thymidylate synthase complementing protein
257309007750	dihydrodipicolinate reductase; Provisional; Region: PRK00048
257309007751	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
257309007752	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
257309007753	HMMPfam hit to PF01113, Dihydrodipicolinate reductase
257309007754	BlastProDom hit to PD004105, PD004105
257309007755	ScanRegExp hit to PS01298, Dihydrodipicolinate reductase signature.
257309007756	guanosine pentaphosphate synthetase I/polynucleotide phosphorylase; Region: pppGpp_PNP; TIGR02696
257309007757	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
257309007758	oligomer interface [polypeptide binding]; other site
257309007759	RNA binding site [nucleotide binding]; other site
257309007760	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
257309007761	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
257309007762	RNase E interface [polypeptide binding]; other site
257309007763	trimer interface [polypeptide binding]; other site
257309007764	active site
257309007765	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
257309007766	putative nucleic acid binding region [nucleotide binding]; other site
257309007767	G-X-X-G motif; other site
257309007768	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
257309007769	RNA binding site [nucleotide binding]; other site
257309007770	domain interface; other site
257309007771	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309007772	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309007773	HMMPfam hit to PF00575, S1 RNA binding domain
257309007774	HMMSmart hit to SM00322, K homology RNA-binding domain
257309007775	ProfileScan hit to PS50084, Type-1 KH domain profile.
257309007776	HMMPfam hit to PF00013, KH domain
257309007777	HMMPfam hit to PF01138, 3' exoribonuclease
257309007778	HMMPfam hit to PF01138, 3' exoribonuclease
257309007779	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
257309007780	16S/18S rRNA binding site [nucleotide binding]; other site
257309007781	S13e-L30e interaction site [polypeptide binding]; other site
257309007782	25S rRNA binding site [nucleotide binding]; other site
257309007783	HMMPfam hit to PF00312, Ribosomal protein S15
257309007784	ScanRegExp hit to PS00362, Ribosomal protein S15 signature.
257309007785	NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These...; Region: nuc_hydro_CaPnhB; cd02650
257309007786	active site
257309007787	HMMPfam hit to PF01156, Inosine-uridine preferring nucleoside hydrolase
257309007788	BlastProDom hit to PD007736, PD007736
257309007789	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
257309007790	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
257309007791	active site
257309007792	Riboflavin kinase; Region: Flavokinase; smart00904
257309007793	HMMPfam hit to PF01687, Riboflavin kinase / FAD synthetase
257309007794	BlastProDom hit to PD003662, PD003662
257309007795	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK03287
257309007796	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
257309007797	RNA binding site [nucleotide binding]; other site
257309007798	active site
257309007799	tRNA Pseudouridine synthase II, C terminal; Region: TruB_C; pfam09142
257309007800	HMMPfam hit to PF01509, TruB family pseudouridylate synthase (N terminal domain)
257309007801	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
257309007802	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
257309007803	FPrintScan hit to PR01399, Enterobactin synthetase component D signature
257309007804	FPrintScan hit to PR01399, Enterobactin synthetase component D signature
257309007805	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
257309007806	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
257309007807	active site
257309007808	metal binding site [ion binding]; metal-binding site
257309007809	ProfileScan hit to PS50185, Metallo-phosphoesterase motif.
257309007810	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
257309007811	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
257309007812	12 probable transmembrane helices predicted for DIP1474 by TMHMM2.0
257309007813	HMMPfam hit to PF01554, Uncharacterized membrane protein family UPF0013
257309007814	HMMPfam hit to PF01554, Uncharacterized membrane protein family UPF0013
257309007815	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
257309007816	DHH family; Region: DHH; pfam01368
257309007817	HMMPfam hit to PF02272, DHHA1 domain
257309007818	HMMPfam hit to PF01368, DHH family
257309007819	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
257309007820	HMMPfam hit to PF02033, Ribosome-binding factor A
257309007821	BlastProDom hit to PD007327, PD007327
257309007822	ScanRegExp hit to PS01319, Ribosome-binding factor A signature.
257309007823	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
257309007824	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
257309007825	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
257309007826	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
257309007827	G1 box; other site
257309007828	putative GEF interaction site [polypeptide binding]; other site
257309007829	GTP/Mg2+ binding site [chemical binding]; other site
257309007830	Switch I region; other site
257309007831	G2 box; other site
257309007832	G3 box; other site
257309007833	Switch II region; other site
257309007834	G4 box; other site
257309007835	G5 box; other site
257309007836	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
257309007837	Translation-initiation factor 2; Region: IF-2; pfam11987
257309007838	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
257309007839	BlastProDom hit to PD186100, PD186100
257309007840	HMMPfam hit to PF03144
257309007841	HMMPfam hit to PF03144
257309007842	HMMPfam hit to PF00009, Elongation factor Tu family
257309007843	HMMSmart hit to SM00173, Ras subfamily of RAS small GTPases
257309007844	FPrintScan hit to PR00449, Transforming protein P21 ras signature
257309007845	FPrintScan hit to PR00449, Transforming protein P21 ras signature
257309007846	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309007847	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309007848	FPrintScan hit to PR00449, Transforming protein P21 ras signature
257309007849	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309007850	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309007851	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007852	ProfileScan hit to PS50315, Glycine-rich region.
257309007853	ProfileScan hit to PS50099, Proline-rich region.
257309007854	FPrintScan hit to PR01217, Proline rich extensin signature
257309007855	ProfileScan hit to PS50310, Alanine-rich region.
257309007856	FPrintScan hit to PR01217, Proline rich extensin signature
257309007857	FPrintScan hit to PR01217, Proline rich extensin signature
257309007858	FPrintScan hit to PR01217, Proline rich extensin signature
257309007859	Protein of unknown function (DUF448); Region: DUF448; pfam04296
257309007860	putative RNA binding cleft [nucleotide binding]; other site
257309007861	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
257309007862	NusA N-terminal domain; Region: NusA_N; pfam08529
257309007863	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
257309007864	RNA binding site [nucleotide binding]; other site
257309007865	homodimer interface [polypeptide binding]; other site
257309007866	NusA-like KH domain; Region: KH_5; pfam13184
257309007867	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
257309007868	G-X-X-G motif; other site
257309007869	ProfileScan hit to PS50084, Type-1 KH domain profile.
257309007870	HMMPfam hit to PF00013, KH domain
257309007871	HMMSmart hit to SM00322, K homology RNA-binding domain
257309007872	HMMPfam hit to PF00013, KH domain
257309007873	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309007874	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
257309007875	Sm and related proteins; Region: Sm_like; cl00259
257309007876	HMMPfam hit to PF02576, Uncharacterized BCR, YhbC family COG0779
257309007877	prolyl-tRNA synthetase; Provisional; Region: PRK09194
257309007878	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
257309007879	dimer interface [polypeptide binding]; other site
257309007880	motif 1; other site
257309007881	active site
257309007882	motif 2; other site
257309007883	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
257309007884	putative deacylase active site [active]
257309007885	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
257309007886	active site
257309007887	motif 3; other site
257309007888	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
257309007889	anticodon binding site; other site
257309007890	HMMPfam hit to PF03129
257309007891	HMMPfam hit to PF00587, tRNA synthetase class II (G, H, P, S and T)
257309007892	ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309007893	FPrintScan hit to PR01046, Prolyl-tRNA synthetase signature
257309007894	FPrintScan hit to PR01046, Prolyl-tRNA synthetase signature
257309007895	FPrintScan hit to PR01046, Prolyl-tRNA synthetase signature
257309007896	FPrintScan hit to PR01046, Prolyl-tRNA synthetase signature
257309007897	hypothetical protein; Validated; Region: PRK02101
257309007898	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
257309007899	active site
257309007900	SAM binding site [chemical binding]; other site
257309007901	homodimer interface [polypeptide binding]; other site
257309007902	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases.
257309007903	Uncharacterized conserved protein [Function unknown]; Region: COG0397
257309007904	hypothetical protein; Validated; Region: PRK00029
257309007905	HMMPfam hit to PF02696, Uncharacterized ACR, YdiU/UPF0061 family
257309007906	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
257309007907	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
257309007908	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
257309007909	HMMPfam hit to PF02492, Cobalamin synthesis protein/P47K
257309007910	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007911	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
257309007912	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
257309007913	DNA binding site [nucleotide binding]
257309007914	active site
257309007915	HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferase, DNA binding domain
257309007916	ScanRegExp hit to PS00374, Methylated-DNA--protein-cysteine methyltransferase active site.
257309007917	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
257309007918	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
257309007919	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
257309007920	catalytic triad [active]
257309007921	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase
257309007922	ScanRegExp hit to PS00237, G-protein coupled receptors family 1 signature.
257309007923	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
257309007924	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
257309007925	Walker A motif; other site
257309007926	homodimer interface [polypeptide binding]; other site
257309007927	ATP binding site [chemical binding]; other site
257309007928	hydroxycobalamin binding site [chemical binding]; other site
257309007929	Walker B motif; other site
257309007930	HMMPfam hit to PF02572, ATP:corrinoid adenosyltransferase BtuR/CobO/CobP
257309007931	Pseudogene. Similar in its full length to Streptomyces coelicolor  chelatase SCI8.35 TR:Q9RJ18 (EMBL:AL132644) (672 aa) fasta scores: E(): 3.9e-87, 50.07% id in 669 aa, and to Chlorobium vibrioforme magnesium-chelatase 67 kDa subunit BchD SW:BCHD_CHLVI (O50313) (619 aa) fasta scores: E(): 8.1e-30, 31.9% id in 652 aa and N-terminal region similar to Rhodobacter capsulatus magnesium-chelatase 38 kDa subunit BchI SW:BCHI_RHOCA (P26239) (350 aa) fasta scores: E(): 6.7e-35, 45.79% id in 321 aa. Presents a frameshift at residue 361; magnesium chelatase (pseudogene)
257309007932	ProfileScan hit to PS50234, VWFA domain profile.
257309007933	HMMSmart hit to SM00327, von Willebrand factor (vWF) type A domain
257309007934	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309007935	HMMPfam hit to PF01078, Magnesium chelatase, subunit ChlI
257309007936	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309007937	malate:quinone oxidoreductase; Validated; Region: PRK05257
257309007938	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
257309007939	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
257309007940	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
257309007941	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309007942	mycothione reductase; Region: mycothione_red; TIGR03452
257309007943	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
257309007944	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
257309007945	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase
257309007946	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007947	ScanRegExp hit to PS00076, Pyridine nucleotide-disulphide oxidoreductases class-I active site.
257309007948	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309007949	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007950	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309007951	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007952	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309007953	FPrintScan hit to PR00945, Mercuric reductase class II signature
257309007954	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007955	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007956	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007957	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
257309007958	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309007959	cobyric acid synthase; Provisional; Region: PRK00784
257309007960	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
257309007961	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
257309007962	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
257309007963	catalytic triad [active]
257309007964	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase
257309007965	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
257309007966	active site
257309007967	HMMPfam hit to PF00557, metallopeptidase M24
257309007968	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309007969	ScanRegExp hit to PS00680, Methionine aminopeptidase subfamily 1 signature.
257309007970	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309007971	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309007972	FPrintScan hit to PR00599, Methionine aminopeptidase-1 signature
257309007973	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
257309007974	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
257309007975	HMMPfam hit to PF00905, Penicillin binding protein transpeptidase domain
257309007976	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007977	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309007978	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
257309007979	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
257309007980	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
257309007981	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
257309007982	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
257309007983	active site
257309007984	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
257309007985	protein binding site [polypeptide binding]; other site
257309007986	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
257309007987	putative substrate binding region [chemical binding]; other site
257309007988	4 probable transmembrane helices predicted for DIP1499 by TMHMM2.0
257309007989	HMMSmart hit to SM00228, Domain present in PSD-95, Dlg, and ZO-1/2.
257309007990	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309007991	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
257309007992	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
257309007993	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
257309007994	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
257309007995	HMMPfam hit to PF02670, 1-deoxy-D-xylulose 5-phosphate reductoisomerase
257309007996	Protein of unknown function (DUF2631); Region: DUF2631; pfam10939
257309007997	1 probable transmembrane helix predicted for DIP1501 by TMHMM2.0
257309007998	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14459
257309007999	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309008000	FeS/SAM binding site; other site
257309008001	Uncharacterized integral membrane protein [Function unknown]; Region: COG5416
257309008002	2 probable transmembrane helices predicted for DIP1503 by TMHMM2.0
257309008003	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
257309008004	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
257309008005	HMMPfam hit to PF01148, Phosphatidate cytidylyltransferase
257309008006	ScanRegExp hit to PS01315, Phosphatidate cytidylyltransferase signature.
257309008007	7 probable transmembrane helices predicted for DIP1504 by TMHMM2.0
257309008008	ribosome recycling factor; Reviewed; Region: frr; PRK00083
257309008009	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
257309008010	hinge region; other site
257309008011	HMMPfam hit to PF01765, Ribosome recycling factor
257309008012	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
257309008013	putative nucleotide binding site [chemical binding]; other site
257309008014	uridine monophosphate binding site [chemical binding]; other site
257309008015	homohexameric interface [polypeptide binding]; other site
257309008016	HMMPfam hit to PF00696, Amino acid kinase
257309008017	elongation factor Ts; Provisional; Region: tsf; PRK09377
257309008018	UBA/TS-N domain; Region: UBA; pfam00627
257309008019	Elongation factor TS; Region: EF_TS; pfam00889
257309008020	Elongation factor TS; Region: EF_TS; pfam00889
257309008021	HMMPfam hit to PF00889, Elongation factor TS
257309008022	ProfileScan hit to PS50310, Alanine-rich region.
257309008023	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008024	ScanRegExp hit to PS01127, Elongation factor Ts signature 2.
257309008025	HMMPfam hit to PF00627, UBA domain
257309008026	ScanRegExp hit to PS01126, Elongation factor Ts signature 1.
257309008027	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
257309008028	rRNA interaction site [nucleotide binding]; other site
257309008029	S8 interaction site; other site
257309008030	putative laminin-1 binding site; other site
257309008031	HMMPfam hit to PF00318, Ribosomal protein S2
257309008032	FPrintScan hit to PR00395, Ribosomal protein S2 signature
257309008033	FPrintScan hit to PR00395, Ribosomal protein S2 signature
257309008034	FPrintScan hit to PR00395, Ribosomal protein S2 signature
257309008035	FPrintScan hit to PR00395, Ribosomal protein S2 signature
257309008036	FPrintScan hit to PR00395, Ribosomal protein S2 signature
257309008037	FPrintScan hit to PR00395, Ribosomal protein S2 signature
257309008038	ScanRegExp hit to PS00962, Ribosomal protein S2 signature 1.
257309008039	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
257309008040	Peptidase family M23; Region: Peptidase_M23; pfam01551
257309008041	HMMPfam hit to PF01551, Peptidase M23/M37
257309008042	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
257309008043	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
257309008044	active site
257309008045	DNA binding site [nucleotide binding]
257309008046	Int/Topo IB signature motif; other site
257309008047	HMMPfam hit to PF00589, Phage integrase
257309008048	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like domain
257309008049	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
257309008050	DNA protecting protein DprA; Region: dprA; TIGR00732
257309008051	HMMPfam hit to PF02481, SMF family
257309008052	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008053	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
257309008054	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
257309008055	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309008056	Walker A motif; other site
257309008057	ATP binding site [chemical binding]; other site
257309008058	Walker B motif; other site
257309008059	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
257309008060	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309008061	HMMPfam hit to PF01078, Magnesium chelatase, subunit ChlI
257309008062	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008063	hypothetical protein; Reviewed; Region: PRK12497
257309008064	HMMPfam hit to PF02021, Uncharacterised protein family UPF0102
257309008065	Protein of unknown function (DUF2469); Region: DUF2469; pfam10611
257309008066	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
257309008067	RNA/DNA hybrid binding site [nucleotide binding]; other site
257309008068	active site
257309008069	HMMPfam hit to PF01351, Ribonuclease HII
257309008070	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
257309008071	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
257309008072	Catalytic site [active]
257309008073	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
257309008074	HMMPfam hit to PF00461, Signal peptidase I
257309008075	FPrintScan hit to PR00727, Bacterial leader peptidase 1 (S26A) family signature
257309008076	ScanRegExp hit to PS00761, Signal peptidases I signature 3.
257309008077	FPrintScan hit to PR00727, Bacterial leader peptidase 1 (S26A) family signature
257309008078	HMMPfam hit to PF00461, Signal peptidase I
257309008079	FPrintScan hit to PR00727, Bacterial leader peptidase 1 (S26A) family signature
257309008080	ScanRegExp hit to PS00501, Signal peptidases I serine active site.
257309008081	1 probable transmembrane helix predicted for DIP1516 by TMHMM2.0
257309008082	putative transposase OrfB; Reviewed; Region: PHA02517
257309008083	HTH-like domain; Region: HTH_21; pfam13276
257309008084	Integrase core domain; Region: rve; pfam00665
257309008085	Integrase core domain; Region: rve_2; pfam13333
257309008086	HMMPfam hit to PF00665, Integrase core domain
257309008087	Homeodomain-like domain; Region: HTH_23; cl17451
257309008088	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309008089	Predicted helix-turn-helix motif with score 1129 (+3.03 SD) at aa 28-49, sequence YGSRAVANRLGVRREQVRHLED
257309008090	Htaa; Region: HtaA; pfam04213
257309008091	1 probable transmembrane helix predicted for DIP1519 by TMHMM2.0
257309008092	Htaa; Region: HtaA; pfam04213
257309008093	1 probable transmembrane helix predicted for DIP1520 by TMHMM2.0
257309008094	Pseudogene. Similar to parts of Corynephage 304L integrase Int TR:Q9ZWV7 (EMBL:Y18058) blast scores: E(): 4e-11, score: 69 Identities = 34/62 (54%); E(): 1.0, Score = 34 Identities = 20/76 (26%). Presents frameshifts at residues 81 and 107; phage related integrase (pseudogene)
257309008095	Homeodomain-like domain; Region: HTH_23; cl17451
257309008096	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309008097	Predicted helix-turn-helix motif with score 1129 (+3.03 SD) at aa 28-49, sequence YGSRAVANRLGVRREQVRHLED
257309008098	putative transposase OrfB; Reviewed; Region: PHA02517
257309008099	HTH-like domain; Region: HTH_21; pfam13276
257309008100	Integrase core domain; Region: rve; pfam00665
257309008101	Integrase core domain; Region: rve_2; pfam13333
257309008102	HMMPfam hit to PF00665, Integrase core domain
257309008103	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
257309008104	HMMPfam hit to PF01245, Ribosomal protein L19
257309008105	BlastProDom hit to PD002979, PD002979
257309008106	FPrintScan hit to PR00061, Ribosomal protein L19 signature
257309008107	ScanRegExp hit to PS01015, Ribosomal protein L19 signature.
257309008108	FPrintScan hit to PR00061, Ribosomal protein L19 signature
257309008109	FPrintScan hit to PR00061, Ribosomal protein L19 signature
257309008110	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
257309008111	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
257309008112	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
257309008113	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
257309008114	RNA binding site [nucleotide binding]; other site
257309008115	HMMPfam hit to PF00575, S1 RNA binding domain
257309008116	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309008117	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309008118	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
257309008119	HMMPfam hit to PF01746, tRNA (Guanine-1)-methyltransferase
257309008120	BlastProDom hit to PD004978, PD004978
257309008121	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309008122	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
257309008123	RimM N-terminal domain; Region: RimM; pfam01782
257309008124	PRC-barrel domain; Region: PRC; pfam05239
257309008125	HMMPfam hit to PF01782, RimM
257309008126	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14520
257309008127	ProfileScan hit to PS50310, Alanine-rich region.
257309008128	HMMPfam hit to PF00886, Ribosomal protein S16
257309008129	signal recognition particle protein; Provisional; Region: PRK10867
257309008130	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
257309008131	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
257309008132	P loop; other site
257309008133	GTP binding site [chemical binding]; other site
257309008134	Signal peptide binding domain; Region: SRP_SPB; pfam02978
257309008135	HMMPfam hit to PF02978, Signal peptide binding domain
257309008136	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309008137	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain
257309008138	BlastProDom hit to PD000819, PD000819
257309008139	ScanRegExp hit to PS00300, SRP54-type proteins GTP-binding domain signature.
257309008140	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008141	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain
257309008142	PII uridylyl-transferase; Provisional; Region: glnD; PRK00227
257309008143	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
257309008144	metal binding triad; other site
257309008145	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
257309008146	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; smart00471
257309008147	HMMPfam hit to PF01966, HD domain
257309008148	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
257309008149	Nitrogen regulatory protein P-II; Region: P-II; smart00938
257309008150	BlastProDom hit to PD001194, PD001194; HMMPfam hit to PF00543, Nitrogen regulatory protein P-II
257309008151	FPrintScan hit to PR00340, P-II protein signature
257309008152	ScanRegExp hit to PS00638, P-II protein C-terminal region signature.
257309008153	FPrintScan hit to PR00340, P-II protein signature
257309008154	ScanRegExp hit to PS00496, P-II protein urydylation site.
257309008155	FPrintScan hit to PR00340, P-II protein signature
257309008156	FPrintScan hit to PR00340, P-II protein signature
257309008157	Pseudogene. Similar to Corynebacterium glutamicum low affinity ammonium uptake protein AmtP SWALL:Q9X704 (EMBL:AJ010319) (438 aa) fasta scores: E(): 4e-53, 54.4% id in 261 aa. Presents multiple frameshifts at residues 103, 121 and 249 and lacks stop codon; low affinity ammonium uptake protein (pseudogene)
257309008158	2 probable transmembrane helices predicted for DIP1537 by TMHMM2.0; 4 probable transmembrane helices predicted for DIP1536 by TMHMM2.0
257309008159	ScanRegExp hit to PS01219, Ammonium transporters signature.
257309008160	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
257309008161	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
257309008162	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
257309008163	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain
257309008164	BlastProDom hit to PD000819, PD000819
257309008165	ScanRegExp hit to PS00300, SRP54-type proteins GTP-binding domain signature.
257309008166	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309008167	ScanRegExp hit to PS00216, Sugar transport proteins signature 1.
257309008168	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008169	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain
257309008170	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
257309008171	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
257309008172	Walker A/P-loop; other site
257309008173	ATP binding site [chemical binding]; other site
257309008174	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
257309008175	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
257309008176	ABC transporter signature motif; other site
257309008177	Walker B; other site
257309008178	D-loop; other site
257309008179	H-loop/switch region; other site
257309008180	HMMPfam hit to PF02483, SMC family, C-terminal domain
257309008181	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309008182	Predicted helix-turn-helix motif with score 974 (+2.50 SD) at aa 482-503, sequence ESKIETLESHRMTRNAVKQWEK
257309008183	HMMPfam hit to PF02463, SMC domain N terminal domain
257309008184	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309008185	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008186	Acylphosphatase; Region: Acylphosphatase; cl00551
257309008187	HMMPfam hit to PF00708, Acylphosphatase
257309008188	BlastProDom hit to PD001884, PD001884
257309008189	ScanRegExp hit to PS00150, Acylphosphatase signature 1.
257309008190	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
257309008191	amino acid carrier protein; Region: agcS; TIGR00835
257309008192	HMMPfam hit to PF01235, Sodium:alanine symporter family
257309008193	9 probable transmembrane helices predicted for DIP1542 by TMHMM2.0
257309008194	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309008195	ProfileScan hit to PS50285, Permeases for amino acids and related compounds, family I.
257309008196	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309008197	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309008198	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309008199	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309008200	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309008201	ScanRegExp hit to PS00873, Sodium:alanine symporter family signature.
257309008202	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
257309008203	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
257309008204	DNA binding site [nucleotide binding]
257309008205	catalytic residue [active]
257309008206	H2TH interface [polypeptide binding]; other site
257309008207	putative catalytic residues [active]
257309008208	turnover-facilitating residue; other site
257309008209	intercalation triad [nucleotide binding]; other site
257309008210	8OG recognition residue [nucleotide binding]; other site
257309008211	putative reading head residues; other site
257309008212	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
257309008213	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
257309008214	BlastProDom hit to PD003680, PD003680; HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase
257309008215	ScanRegExp hit to PS01242, Formamidopyrimidine-DNA glycosylase signature.
257309008216	ribonuclease III; Reviewed; Region: rnc; PRK00102
257309008217	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
257309008218	dimerization interface [polypeptide binding]; other site
257309008219	active site
257309008220	metal binding site [ion binding]; metal-binding site
257309008221	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
257309008222	dsRNA binding site [nucleotide binding]; other site
257309008223	ProfileScan hit to PS50137, Double stranded RNA-binding domain (dsRBD) profile.
257309008224	HMMSmart hit to SM00358, Double-stranded RNA binding motif
257309008225	HMMPfam hit to PF00035, Double-stranded RNA binding motif
257309008226	HMMSmart hit to SM00535, Ribonuclease III family
257309008227	ProfileScan hit to PS50142, Ribonuclease III family domain profile.
257309008228	HMMPfam hit to PF00636, RNase3 domain.
257309008229	ScanRegExp hit to PS00517, Ribonuclease III family signature.
257309008230	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
257309008231	HMMPfam hit to PF02620, Uncharacterized ACR, COG1399
257309008232	Cell division initiation protein [Cell division and chromosome partitioning]; Region: DivIVA; COG3599
257309008233	glutamate dehydrogenase; Provisional; Region: PRK09414
257309008234	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
257309008235	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
257309008236	NAD(P) binding site [chemical binding]; other site
257309008237	HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
257309008238	FPrintScan hit to PR00082, Glutamate/leucine/phenylalanine/valine dehydrogenase signature
257309008239	FPrintScan hit to PR00082, Glutamate/leucine/phenylalanine/valine dehydrogenase signature
257309008240	FPrintScan hit to PR00082, Glutamate/leucine/phenylalanine/valine dehydrogenase signature
257309008241	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
257309008242	ScanRegExp hit to PS00074, Glu / Leu / Phe / Val dehydrogenases active site.
257309008243	FPrintScan hit to PR00082, Glutamate/leucine/phenylalanine/valine dehydrogenase signature
257309008244	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
257309008245	HMMPfam hit to PF02595, Uncharacterized BCR, COG1929
257309008246	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
257309008247	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
257309008248	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like6; cd05664
257309008249	metal binding site [ion binding]; metal-binding site
257309008250	putative dimer interface [polypeptide binding]; other site
257309008251	HMMPfam hit to PF01546, Peptidase M20/M25/M40
257309008252	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
257309008253	homodimer interface [polypeptide binding]; other site
257309008254	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
257309008255	active site pocket [active]
257309008256	HMMPfam hit to PF00343, Carbohydrate phosphorylase
257309008257	HMMPfam hit to PF00343, Carbohydrate phosphorylase
257309008258	ScanRegExp hit to PS00102, Phosphorylase pyridoxal-phosphate attachment site.
257309008259	pyruvate kinase; Provisional; Region: PRK06247
257309008260	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
257309008261	domain interfaces; other site
257309008262	active site
257309008263	HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain
257309008264	BlastProDom hit to PD001009, PD001009
257309008265	HMMPfam hit to PF00224, Pyruvate kinase, barrel domain
257309008266	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008267	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008268	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008269	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008270	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008271	ScanRegExp hit to PS00110, Pyruvate kinase active site signature.
257309008272	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008273	FPrintScan hit to PR01050, Pyruvate kinase signature
257309008274	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
257309008275	HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase
257309008276	7 probable transmembrane helices predicted for DIP1554 by TMHMM2.0
257309008277	ScanRegExp hit to PS00030, Eukaryotic RNA Recognition Motif (RRM) RNP-1 region signature.
257309008278	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
257309008279	active site
257309008280	ribulose/triose binding site [chemical binding]; other site
257309008281	phosphate binding site [ion binding]; other site
257309008282	substrate (anthranilate) binding pocket [chemical binding]; other site
257309008283	product (indole) binding pocket [chemical binding]; other site
257309008284	BlastProDom hit to PD001511, PD001511; HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase
257309008285	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309008286	Tryptophan-associated transmembrane protein (Trp_oprn_chp); Region: Trp_oprn_chp; cl17850
257309008287	3 probable transmembrane helices predicted for DIP1556 by TMHMM2.0
257309008288	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
257309008289	HMMPfam hit to PF01502, Phosphoribosyl-AMP cyclohydrolase
257309008290	BlastProDom hit to PD002610, PD002610
257309008291	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
257309008292	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
257309008293	substrate binding site [chemical binding]; other site
257309008294	glutamase interaction surface [polypeptide binding]; other site
257309008295	HMMPfam hit to PF00977, Histidine biosynthesis protein
257309008296	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309008297	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309008298	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
257309008299	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
257309008300	active site
257309008301	HMMPfam hit to PF00459, Inositol monophosphatase
257309008302	FPrintScan hit to PR00378, Inositol phosphatase signature
257309008303	FPrintScan hit to PR00378, Inositol phosphatase signature
257309008304	FPrintScan hit to PR00378, Inositol phosphatase signature
257309008305	FPrintScan hit to PR00378, Inositol phosphatase signature
257309008306	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
257309008307	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
257309008308	catalytic residues [active]
257309008309	HMMPfam hit to PF00977, Histidine biosynthesis protein
257309008310	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309008311	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309008312	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
257309008313	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
257309008314	putative active site [active]
257309008315	oxyanion strand; other site
257309008316	catalytic triad [active]
257309008317	HMMPfam hit to PF00117, Glutamine amidotransferase class-I
257309008318	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309008319	ScanRegExp hit to PS00442, Glutamine amidotransferases class-I active site.
257309008320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309008321	Major Facilitator Superfamily; Region: MFS_1; pfam07690
257309008322	putative substrate translocation pore; other site
257309008323	HMMPfam hit to PF00083, Sugar (and other) transporter
257309008324	12 probable transmembrane helices predicted for DIP1562 by TMHMM2.0
257309008325	2 probable transmembrane helices predicted for DIP1563 by TMHMM2.0
257309008326	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
257309008327	putative active site pocket [active]
257309008328	4-fold oligomerization interface [polypeptide binding]; other site
257309008329	metal binding residues [ion binding]; metal-binding site
257309008330	3-fold/trimer interface [polypeptide binding]; other site
257309008331	BlastProDom hit to PD002282, PD002282
257309008332	HMMPfam hit to PF00475, Imidazoleglycerol-phosphate dehydratase
257309008333	ScanRegExp hit to PS00955, Imidazoleglycerol-phosphate dehydratase signature 2.
257309008334	ScanRegExp hit to PS00954, Imidazoleglycerol-phosphate dehydratase signature 1.
257309008335	histidinol-phosphate aminotransferase; Provisional; Region: PRK03317
257309008336	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309008337	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309008338	homodimer interface [polypeptide binding]; other site
257309008339	catalytic residue [active]
257309008340	HMMPfam hit to PF00155, Aminotransferase class I and II
257309008341	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
257309008342	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
257309008343	NAD binding site [chemical binding]; other site
257309008344	dimerization interface [polypeptide binding]; other site
257309008345	product binding site; other site
257309008346	substrate binding site [chemical binding]; other site
257309008347	zinc binding site [ion binding]; other site
257309008348	catalytic residues [active]
257309008349	BlastProDom hit to PD002680, PD002680; HMMPfam hit to PF00815, Histidinol dehydrogenase
257309008350	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008351	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008352	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008353	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008354	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008355	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008356	FPrintScan hit to PR00083, Histidinol dehydrogenase signature
257309008357	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
257309008358	tetracycline repressor protein TetR; Provisional; Region: PRK13756
257309008359	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309008360	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
257309008361	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309008362	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309008363	ScanRegExp hit to PS01081, Bacterial regulatory proteins, tetR family signature.
257309008364	FPrintScan hit to PR00400, Tetracycline repressor protein signature
257309008365	Predicted helix-turn-helix motif with score 1855 (+5.50 SD) at aa 60-81, sequence MTMRRLATHLGVAPGALYWHFK
257309008366	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309008367	HMMPfam hit to PF02909, Tetracyclin repressor, C-terminal all-alpha domain
257309008368	FPrintScan hit to PR00400, Tetracycline repressor protein signature
257309008369	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
257309008370	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
257309008371	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
257309008372	active site
257309008373	catalytic site [active]
257309008374	HMMPfam hit to PF02922, Isoamylase N-terminal domain
257309008375	HMMPfam hit to PF00128, Alpha amylase, catalytic domain
257309008376	DNA polymerase III subunit epsilon; Validated; Region: PRK06195
257309008377	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
257309008378	active site
257309008379	catalytic site [active]
257309008380	substrate binding site [chemical binding]; other site
257309008381	HMMSmart hit to SM00479, No definition
257309008382	HMMPfam hit to PF00929, Exonuclease
257309008383	HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain
257309008384	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
257309008385	synthetase active site [active]
257309008386	NTP binding site [chemical binding]; other site
257309008387	metal binding site [ion binding]; metal-binding site
257309008388	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
257309008389	RNA binding surface [nucleotide binding]; other site
257309008390	HMMSmart hit to SM00363, S4 RNA-binding domain
257309008391	HMMPfam hit to PF01479, S4 domain
257309008392	2 probable transmembrane helices predicted for DIP1577 by TMHMM2.0
257309008393	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
257309008394	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
257309008395	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
257309008396	HMMPfam hit to PF01205, Uncharacterized protein family UPF0029
257309008397	ScanRegExp hit to PS00910, Uncharacterized protein family UPF0029 signature.
257309008398	threonine dehydratase; Validated; Region: PRK08639
257309008399	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
257309008400	tetramer interface [polypeptide binding]; other site
257309008401	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309008402	catalytic residue [active]
257309008403	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
257309008404	putative Ile/Val binding site [chemical binding]; other site
257309008405	HMMPfam hit to PF00585, C-terminal domain of Threonine dehydratase
257309008406	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme
257309008407	ProfileScan hit to PS50148, Pyridoxalphosphate dependent enzymes.
257309008408	ScanRegExp hit to PS00165, Serine/threonine dehydratases pyridoxal-phosphate attachment site.
257309008409	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
257309008410	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
257309008411	active site
257309008412	PHP Thumb interface [polypeptide binding]; other site
257309008413	metal binding site [ion binding]; metal-binding site
257309008414	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
257309008415	generic binding surface II; other site
257309008416	generic binding surface I; other site
257309008417	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain
257309008418	HMMPfam hit to PF02811, PHP domain C-terminal region
257309008419	HMMSmart hit to SM00481, DNA polymerase alpha chain like domain
257309008420	HMMPfam hit to PF02231, PHP domain N-terminal region
257309008421	Predicted permeases [General function prediction only]; Region: RarD; COG2962
257309008422	EamA-like transporter family; Region: EamA; cl17759
257309008423	10 probable transmembrane helices predicted for DIP1581 by TMHMM2.0
257309008424	HMMPfam hit to PF00892, Integral membrane protein DUF6
257309008425	HMMPfam hit to PF00892, Integral membrane protein DUF6
257309008426	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
257309008427	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
257309008428	RNA binding surface [nucleotide binding]; other site
257309008429	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
257309008430	active site
257309008431	BlastProDom hit to PD001819, PD001819
257309008432	HMMPfam hit to PF00849, RNA pseudouridylate synthase
257309008433	HMMPfam hit to PF01479, S4 domain
257309008434	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
257309008435	HMMPfam hit to PF01252, Signal peptidase (SPase) II
257309008436	4 probable transmembrane helices predicted for DIP1584 by TMHMM2.0
257309008437	FPrintScan hit to PR00781, Lipoprotein signal peptidase (A8) signature
257309008438	ScanRegExp hit to PS00211, ABC transporters family signature.
257309008439	FPrintScan hit to PR00781, Lipoprotein signal peptidase (A8) signature
257309008440	ScanRegExp hit to PS00855, Signal peptidases II signature.
257309008441	FPrintScan hit to PR00781, Lipoprotein signal peptidase (A8) signature
257309008442	ProfileScan hit to PS50099, Proline-rich region.
257309008443	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
257309008444	active site
257309008445	homotetramer interface [polypeptide binding]; other site
257309008446	homodimer interface [polypeptide binding]; other site
257309008447	FPrintScan hit to PR00139, Asparaginase/glutaminase signature
257309008448	HMMPfam hit to PF00710, Asparaginase
257309008449	FPrintScan hit to PR00139, Asparaginase/glutaminase signature
257309008450	FPrintScan hit to PR00139, Asparaginase/glutaminase signature
257309008451	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008452	DNA polymerase IV; Provisional; Region: PRK03348
257309008453	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
257309008454	active site
257309008455	DNA binding site [nucleotide binding]
257309008456	HMMPfam hit to PF00817, impB/mucB/samB family
257309008457	ProfileScan hit to PS50173, UMUC domain (DNA-repair).
257309008458	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
257309008459	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
257309008460	HIGH motif; other site
257309008461	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
257309008462	active site
257309008463	KMSKS motif; other site
257309008464	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
257309008465	tRNA binding surface [nucleotide binding]; other site
257309008466	anticodon binding site; other site
257309008467	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V)
257309008468	FPrintScan hit to PR00984, Isoleucyl-tRNA synthetase signature
257309008469	FPrintScan hit to PR00984, Isoleucyl-tRNA synthetase signature
257309008470	FPrintScan hit to PR00984, Isoleucyl-tRNA synthetase signature
257309008471	FPrintScan hit to PR00984, Isoleucyl-tRNA synthetase signature
257309008472	ScanRegExp hit to PS00178, Aminoacyl-transfer RNA synthetases class-I signature.
257309008473	FPrintScan hit to PR00984, Isoleucyl-tRNA synthetase signature
257309008474	DivIVA domain; Region: DivI1A_domain; TIGR03544
257309008475	Cell division initiation protein [Cell division and chromosome partitioning]; Region: DivIVA; COG3599
257309008476	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
257309008477	ProfileScan hit to PS50310, Alanine-rich region.
257309008478	YGGT family; Region: YGGT; cl00508
257309008479	3 probable transmembrane helices predicted for DIP1591 by TMHMM2.0
257309008480	Protein of unknown function (DUF552); Region: DUF552; cl00775
257309008481	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
257309008482	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
257309008483	HMMPfam hit to PF02578, Uncharacterized ACR, YfiH family COG1496
257309008484	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
257309008485	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
257309008486	nucleotide binding site [chemical binding]; other site
257309008487	SulA interaction site; other site
257309008488	FPrintScan hit to PR00423, Cell division protein FtsZ signature
257309008489	FPrintScan hit to PR00423, Cell division protein FtsZ signature
257309008490	HMMPfam hit to PF00091, Tubulin/FtsZ family
257309008491	FPrintScan hit to PR00423, Cell division protein FtsZ signature
257309008492	FPrintScan hit to PR00423, Cell division protein FtsZ signature
257309008493	ScanRegExp hit to PS01135, FtsZ protein signature 2.
257309008494	FPrintScan hit to PR00423, Cell division protein FtsZ signature
257309008495	ScanRegExp hit to PS01134, FtsZ protein signature 1.
257309008496	FPrintScan hit to PR00423, Cell division protein FtsZ signature
257309008497	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
257309008498	Cell division protein FtsQ; Region: FtsQ; pfam03799
257309008499	1 probable transmembrane helix predicted for DIP1596 by TMHMM2.0
257309008500	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
257309008501	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
257309008502	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
257309008503	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
257309008504	HMMPfam hit to PF02875, Mur ligase, glutamate ligase domain
257309008505	HMMPfam hit to PF01225, Mur ligase, catalytic domain
257309008506	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
257309008507	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
257309008508	active site
257309008509	homodimer interface [polypeptide binding]; other site
257309008510	HMMPfam hit to PF03033
257309008511	cell division protein FtsW; Region: ftsW; TIGR02614
257309008512	ProfileScan hit to PS50323, Arginine-rich region.
257309008513	HMMPfam hit to PF01098, Cell cycle protein
257309008514	8 probable transmembrane helices predicted for DIP1599 by TMHMM2.0
257309008515	ScanRegExp hit to PS00428, Cell cycle proteins ftsW / rodA / spoVE signature.
257309008516	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK00141
257309008517	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
257309008518	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
257309008519	HMMPfam hit to PF02875, Mur ligase, glutamate ligase domain
257309008520	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309008521	HMMPfam hit to PF01225, Mur ligase, catalytic domain
257309008522	ScanRegExp hit to PS01011, Folylpolyglutamate synthase signature 1.
257309008523	ProfileScan hit to PS50205, NAD binding site.
257309008524	FPrintScan hit to PR00420, Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature
257309008525	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
257309008526	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
257309008527	Mg++ binding site [ion binding]; other site
257309008528	putative catalytic motif [active]
257309008529	putative substrate binding site [chemical binding]; other site
257309008530	10 probable transmembrane helices predicted for DIP1601 by TMHMM2.0
257309008531	HMMPfam hit to PF00953, Glycosyl transferase
257309008532	ScanRegExp hit to PS01348, mraY family signature 2.
257309008533	ScanRegExp hit to PS01347, mraY family signature 1.
257309008534	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
257309008535	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
257309008536	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
257309008537	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
257309008538	HMMPfam hit to PF02875, Mur ligase, glutamate ligase domain
257309008539	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309008540	HMMPfam hit to PF01225, Mur ligase, catalytic domain
257309008541	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
257309008542	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
257309008543	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
257309008544	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
257309008545	HMMPfam hit to PF02875, Mur ligase, glutamate ligase domain
257309008546	ScanRegExp hit to PS00307, Legume lectins beta-chain signature.
257309008547	HMMPfam hit to PF01225, Mur ligase, catalytic domain
257309008548	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
257309008549	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
257309008550	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
257309008551	HMMPfam hit to PF00905, Penicillin binding protein transpeptidase domain
257309008552	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008553	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008554	1 probable transmembrane helix predicted for DIP1604 by TMHMM2.0
257309008555	1 probable transmembrane helix predicted for DIP1605 by TMHMM2.0
257309008556	MraW methylase family; Region: Methyltransf_5; cl17771
257309008557	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
257309008558	HMMPfam hit to PF01795, MraW methylase
257309008559	BlastProDom hit to PD004685, PD004685
257309008560	cell division protein MraZ; Reviewed; Region: PRK00326
257309008561	MraZ protein; Region: MraZ; pfam02381
257309008562	MraZ protein; Region: MraZ; pfam02381
257309008563	HMMPfam hit to PF02381, Domain of unknown function UPF0040 family
257309008564	HMMPfam hit to PF02381, Domain of unknown function UPF0040 family
257309008565	Protein of unknown function (DUF3040); Region: DUF3040; pfam11239
257309008566	2 probable transmembrane helices predicted for DIP1608 by TMHMM2.0
257309008567	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
257309008568	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309008569	Coenzyme A binding pocket [chemical binding]; other site
257309008570	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309008571	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
257309008572	FAD binding site [chemical binding]; other site
257309008573	HMMPfam hit to PF02219, Methylenetetrahydrofolate reductase
257309008574	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
257309008575	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
257309008576	substrate binding pocket [chemical binding]; other site
257309008577	chain length determination region; other site
257309008578	substrate-Mg2+ binding site; other site
257309008579	catalytic residues [active]
257309008580	aspartate-rich region 1; other site
257309008581	active site lid residues [active]
257309008582	aspartate-rich region 2; other site
257309008583	HMMPfam hit to PF00348, Polyprenyl synthetase
257309008584	ScanRegExp hit to PS00723, Polyprenyl synthetases signature 1.
257309008585	ScanRegExp hit to PS00444, Polyprenyl synthetases signature 2.
257309008586	carotene biosynthesis associated membrane protein; Region: crt_membr; TIGR03459
257309008587	10 probable transmembrane helices predicted for DIP1613 by TMHMM2.0
257309008588	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
257309008589	Catalytic domain of Protein Kinases; Region: PKc; cd00180
257309008590	active site
257309008591	ATP binding site [chemical binding]; other site
257309008592	substrate binding site [chemical binding]; other site
257309008593	activation loop (A-loop); other site
257309008594	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
257309008595	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309008596	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309008597	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309008598	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
257309008599	HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain
257309008600	HMMSmart hit to SM00219, Tyrosine kinase, catalytic domain; ProfileScan hit to PS50011, Protein kinase domain profile.
257309008601	HMMPfam hit to PF00069, Protein kinase domain
257309008602	ScanRegExp hit to PS00108, Serine/Threonine protein kinases active-site signature.
257309008603	1 probable transmembrane helix predicted for DIP1615 by TMHMM2.0
257309008604	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
257309008605	HMMPfam hit to PF01474, Class-II DAHP synthetase
257309008606	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
257309008607	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
257309008608	putative acyl-acceptor binding pocket; other site
257309008609	HMMPfam hit to PF01553, Acyltransferase
257309008610	ProfileScan hit to PS50239, Phospholipid and glycerol acyltransferase (from 'motifs_6.msf').
257309008611	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008612	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
257309008613	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
257309008614	nucleotide binding site [chemical binding]; other site
257309008615	Tesmin/TSO1-like CXC domain; Region: CXC; pfam03638
257309008616	HMMPfam hit to PF00480, ROK family
257309008617	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
257309008618	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
257309008619	HMMPfam hit to PF00534, Glycosyl transferases group 1
257309008620	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
257309008621	NlpC/P60 family; Region: NLPC_P60; pfam00877
257309008622	HMMPfam hit to PF00877, NLP/P60 family
257309008623	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
257309008624	NlpC/P60 family; Region: NLPC_P60; pfam00877
257309008625	HMMPfam hit to PF00877, NLP/P60 family
257309008626	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008627	1 probable transmembrane helix predicted for DIP1623 by TMHMM2.0
257309008628	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
257309008629	heme bH binding site [chemical binding]; other site
257309008630	intrachain domain interface; other site
257309008631	heme bL binding site [chemical binding]; other site
257309008632	interchain domain interface [polypeptide binding]; other site
257309008633	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N_2; pfam13631
257309008634	Qo binding site; other site
257309008635	9 probable transmembrane helices predicted for DIP1624 by TMHMM2.0
257309008636	HMMPfam hit to PF00033, Cytochrome b(N-terminal)/b6/petB
257309008637	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
257309008638	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
257309008639	iron-sulfur cluster [ion binding]; other site
257309008640	[2Fe-2S] cluster binding site [ion binding]; other site
257309008641	HMMPfam hit to PF00355, Rieske [2Fe-2S] domain
257309008642	FPrintScan hit to PR00162, Rieske 2Fe-2S subunit signature
257309008643	FPrintScan hit to PR00162, Rieske 2Fe-2S subunit signature
257309008644	ScanRegExp hit to PS00200, Rieske iron-sulfur protein signature 2.
257309008645	FPrintScan hit to PR00162, Rieske 2Fe-2S subunit signature
257309008646	3 probable transmembrane helices predicted for DIP1625 by TMHMM2.0
257309008647	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
257309008648	Cytochrome c; Region: Cytochrom_C; pfam00034
257309008649	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
257309008650	1 probable transmembrane helix predicted for DIP1626 by TMHMM2.0
257309008651	HMMPfam hit to PF00034, Cytochrome c
257309008652	ScanRegExp hit to PS00190, Cytochrome c family heme-binding site signature.
257309008653	ScanRegExp hit to PS00190, Cytochrome c family heme-binding site signature.
257309008654	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
257309008655	Subunit I/III interface [polypeptide binding]; other site
257309008656	ProfileScan hit to PS50253, Heme-copper oxidase subunit III profile.
257309008657	5 probable transmembrane helices predicted for DIP1627 by TMHMM2.0
257309008658	HMMPfam hit to PF00510, Cytochrome c oxidase subunit III
257309008659	Cytochrome c oxidase subunit IV; Region: Cyt_c_ox_IV; pfam12270
257309008660	4 probable transmembrane helices predicted for DIP1628 by TMHMM2.0
257309008661	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
257309008662	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
257309008663	HMMPfam hit to PF00116, Cytochrome C oxidase subunit II, periplasmic domain
257309008664	BlastProDom hit to PD000131, PD000131
257309008665	FPrintScan hit to PR01166, Cytochrome c oxidase subunit II signature
257309008666	ScanRegExp hit to PS00078, CO II and nitrous oxide reductase dinuclear copper centers signature.
257309008667	FPrintScan hit to PR01166, Cytochrome c oxidase subunit II signature
257309008668	3 probable transmembrane helices predicted for DIP1629 by TMHMM2.0
257309008669	FPrintScan hit to PR01166, Cytochrome c oxidase subunit II signature
257309008670	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
257309008671	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
257309008672	active site
257309008673	dimer interface [polypeptide binding]; other site
257309008674	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
257309008675	Ligand Binding Site [chemical binding]; other site
257309008676	Molecular Tunnel; other site
257309008677	HMMPfam hit to PF00310, Glutamine amidotransferases class-II
257309008678	HMMPfam hit to PF00733, Asparagine synthase
257309008679	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
257309008680	HMMPfam hit to PF01521, HesB-like domain
257309008681	BlastProDom hit to PD002183, PD002183
257309008682	ScanRegExp hit to PS01152, Hypothetical hesB/yadR/yfhF family signature.
257309008683	Protein of unknown function (DUF3043); Region: DUF3043; pfam11241
257309008684	2 probable transmembrane helices predicted for DIP1632 by TMHMM2.0
257309008685	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
257309008686	homotrimer interface [polypeptide binding]; other site
257309008687	Walker A motif; other site
257309008688	GTP binding site [chemical binding]; other site
257309008689	Walker B motif; other site
257309008690	HMMPfam hit to PF02283, Cobinamide kinase / cobinamide phosphate guanyltransferase
257309008691	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008692	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
257309008693	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
257309008694	putative dimer interface [polypeptide binding]; other site
257309008695	active site pocket [active]
257309008696	putative cataytic base [active]
257309008697	HMMPfam hit to PF02277, Phosphoribosyltransferase
257309008698	cobalamin synthase; Reviewed; Region: cobS; PRK00235
257309008699	HMMPfam hit to PF02654, Cobalamin-5-phosphate synthase
257309008700	7 probable transmembrane helices predicted for DIP1635 by TMHMM2.0
257309008701	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
257309008702	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
257309008703	homodimer interface [polypeptide binding]; other site
257309008704	substrate-cofactor binding pocket; other site
257309008705	catalytic residue [active]
257309008706	HMMPfam hit to PF01063, Aminotransferase class IV
257309008707	BlastProDom hit to PD001961, PD001961
257309008708	ScanRegExp hit to PS00770, Aminotransferases class-IV signature.
257309008709	multifunctional aminopeptidase A; Provisional; Region: PRK00913
257309008710	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
257309008711	interface (dimer of trimers) [polypeptide binding]; other site
257309008712	Substrate-binding/catalytic site; other site
257309008713	Zn-binding sites [ion binding]; other site
257309008714	HMMPfam hit to PF02789, Cytosol aminopeptidase, N-terminal domain
257309008715	HMMPfam hit to PF00883, Cytosol aminopeptidase, catalytic domain
257309008716	FPrintScan hit to PR00481, Cytosol aminopeptidase signature
257309008717	FPrintScan hit to PR00481, Cytosol aminopeptidase signature
257309008718	FPrintScan hit to PR00481, Cytosol aminopeptidase signature
257309008719	ScanRegExp hit to PS00277, Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1.
257309008720	FPrintScan hit to PR00481, Cytosol aminopeptidase signature
257309008721	ScanRegExp hit to PS00631, Cytosol aminopeptidase signature.
257309008722	FPrintScan hit to PR00481, Cytosol aminopeptidase signature
257309008723	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
257309008724	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
257309008725	E3 interaction surface; other site
257309008726	lipoyl attachment site [posttranslational modification]; other site
257309008727	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
257309008728	E3 interaction surface; other site
257309008729	lipoyl attachment site [posttranslational modification]; other site
257309008730	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
257309008731	E3 interaction surface; other site
257309008732	lipoyl attachment site [posttranslational modification]; other site
257309008733	e3 binding domain; Region: E3_binding; pfam02817
257309008734	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
257309008735	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309008736	ScanRegExp hit to PS00189, 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
257309008737	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309008738	ScanRegExp hit to PS00189, 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
257309008739	HMMPfam hit to PF00364, Biotin-requiring enzyme
257309008740	ScanRegExp hit to PS00189, 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
257309008741	HMMPfam hit to PF02817, e3 binding domain
257309008742	HMMPfam hit to PF00198, 2-oxo acid dehydrogenases acyltransferase (catalytic domain)
257309008743	BlastProDom hit to PD001115, PD001115
257309008744	lipoate-protein ligase B; Provisional; Region: PRK14345
257309008745	BlastProDom hit to PD006086, PD006086
257309008746	HMMPfam hit to PF03099
257309008747	ScanRegExp hit to PS01313, Lipoate-protein ligase B signature.
257309008748	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008749	lipoyl synthase; Provisional; Region: PRK05481
257309008750	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309008751	FeS/SAM binding site; other site
257309008752	HMMPfam hit to PF02546, Lipoate synthase
257309008753	Domain of unknown function (DUF4191); Region: DUF4191; pfam13829
257309008754	2 probable transmembrane helices predicted for DIP1642 by TMHMM2.0
257309008755	RDD family; Region: RDD; pfam06271
257309008756	3 probable transmembrane helices predicted for DIP1643 by TMHMM2.0
257309008757	glutamine synthetase, type I; Region: GlnA; TIGR00653
257309008758	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
257309008759	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
257309008760	HMMPfam hit to PF00120, Glutamine synthetase
257309008761	ScanRegExp hit to PS00180, Glutamine synthetase signature 1.
257309008762	ScanRegExp hit to PS00181, Glutamine synthetase ATP-binding region signature.
257309008763	BlastProDom hit to PD001057, PD001057
257309008764	Anomalous G+C content (50.4%) and dinucleotide signature.  phage-related and antibiotic resistance-related pathogenicity island. Not present in C.glutamicum
257309008765	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
257309008766	2 probable transmembrane helices predicted for DIP1647 by TMHMM2.0
257309008767	Pseudogene. Similar to Corynebacterium striatum Tnp1250A or Tnp1250B SWALL:Q9ET89 (EMBL:AF024666) (416 aa) fasta scores: E(): 1.4e-129, 79.15% id in 403 aa, and to Mycobacterium tuberculosis transposase for insertion sequence element IS1081 (Rv1199c or MTCI364.11c) and (Rv2512c or MTCY07a7.18c) SWALL:TRA1_MYCTU (SWALL:P35882) (415 aa) fasta scores: E(): 6.4e-87, 54.7% id in 404 aa. Presents frameshifts at residues 155 and 184 and an in-frame stop codon;IS element transposase (pseudogene)
257309008768	HMMPfam hit to PF00872, Transposase, Mutator family
257309008769	ScanRegExp hit to PS01007, Transposases, Mutator family, signature.
257309008770	HMMPfam hit to PF00872, Transposase, Mutator family
257309008771	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
257309008772	Short repeats of unknown function; Region: ALF; pfam03752
257309008773	Short repeats of unknown function; Region: ALF; pfam03752
257309008774	Short repeats of unknown function; Region: ALF; pfam03752
257309008775	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
257309008776	ProfileScan hit to PS50310, Alanine-rich region.
257309008777	ProfileScan hit to PS50111, MCP (methyl-accepting chemetoxis protein) intracellular domain.
257309008778	Alpha-L-arabinofuranosidase B (ABFB); Region: AbfB; pfam05270
257309008779	LGFP repeat; Region: LGFP; pfam08310
257309008780	LGFP repeat; Region: LGFP; pfam08310
257309008781	LGFP repeat; Region: LGFP; pfam08310
257309008782	AAA domain; Region: AAA_13; pfam13166
257309008783	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309008784	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
257309008785	1 probable transmembrane helix predicted for DIP1658 by TMHMM2.0
257309008786	Predicted peptidase [General function prediction only]; Region: COG4099
257309008787	CsbD-like; Region: CsbD; pfam05532
257309008788	Predicted permease [General function prediction only]; Region: COG2056
257309008789	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
257309008790	12 probable transmembrane helices predicted for DIP1661 by TMHMM2.0
257309008791	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309008792	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309008793	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309008794	Transcriptional regulators [Transcription]; Region: FadR; COG2186
257309008795	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309008796	DNA-binding site [nucleotide binding]; DNA binding site
257309008797	FCD domain; Region: FCD; pfam07729
257309008798	HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309008799	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309008800	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309008801	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309008802	putative substrate translocation pore; other site
257309008803	11 probable transmembrane helices predicted for DIP1663 by TMHMM2.0
257309008804	HMMPfam hit to PF00083, Sugar (and other) transporter
257309008805	ScanRegExp hit to PS00216, Sugar transport proteins signature 1.
257309008806	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_17; cd04676
257309008807	nudix motif; other site
257309008808	HMMPfam hit to PF00293, MutT-like domain
257309008809	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309008810	ScanRegExp hit to PS00893, Nudix hydrolase signature.
257309008811	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309008812	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
257309008813	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
257309008814	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309008815	catalytic residue [active]
257309008816	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme
257309008817	ScanRegExp hit to PS00165, Serine/threonine dehydratases pyridoxal-phosphate attachment site.
257309008818	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
257309008819	active site
257309008820	catalytic site [active]
257309008821	1 probable transmembrane helix predicted for DIP1667 by TMHMM2.0
257309008822	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cd00232
257309008823	heme binding pocket [chemical binding]; other site
257309008824	heme ligand [chemical binding]; other site
257309008825	HMMPfam hit to PF01126, Heme oxygenase
257309008826	FPrintScan hit to PR00088, Haem oxygenase signature
257309008827	FPrintScan hit to PR00088, Haem oxygenase signature
257309008828	FPrintScan hit to PR00088, Haem oxygenase signature
257309008829	ScanRegExp hit to PS00593, Heme oxygenase signature.
257309008830	FPrintScan hit to PR00088, Haem oxygenase signature
257309008831	FPrintScan hit to PR00088, Haem oxygenase signature
257309008832	FPrintScan hit to PR00088, Haem oxygenase signature
257309008833	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Provisional; Region: PRK14109
257309008834	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
257309008835	metal binding triad; other site
257309008836	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
257309008837	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
257309008838	metal binding triad; other site
257309008839	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
257309008840	ScanRegExp hit to PS00599, Aminotransferases class-II pyridoxal-phosphate attachment site.
257309008841	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
257309008842	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
257309008843	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
257309008844	BlastProDom hit to PD001057, PD001057
257309008845	HMMPfam hit to PF00120, Glutamine synthetase
257309008846	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cd07374
257309008847	putative active site; other site
257309008848	putative metal binding residues [ion binding]; other site
257309008849	signature motif; other site
257309008850	putative triphosphate binding site [ion binding]; other site
257309008851	The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family; Region: CHAD; smart00880
257309008852	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
257309008853	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
257309008854	FPrintScan hit to PR00959, Mevalonate kinase signature
257309008855	FPrintScan hit to PR00473, Galactokinase signature
257309008856	FPrintScan hit to PR00473, Galactokinase signature
257309008857	FPrintScan hit to PR00959, Mevalonate kinase signature
257309008858	FPrintScan hit to PR00473, Galactokinase signature
257309008859	FPrintScan hit to PR00959, Mevalonate kinase signature
257309008860	Pseudogene. Similar to Corynebacterium xerosis IS element hypothetical 20.7 kDa protein TnpCX TR:Q46485 (EMBL:U21300) (190 aa) fasta scores: E(): 0.0067, 53.33% id in 45 aa; transposase (pseudogene)
257309008861	Pseudogene. Similar to Rhizobium loti ribonuclease MLL0040 TR:Q98NP8 (EMBL:AP002994) blast scores: E(): 2e-06, score: 53 40% id, and to Bacillus subtilis ribonuclease R Rnr or VacB SW:RNR_BACSU (O32231) blast scores: E(): 1e-04, score: 47 43% id. Presents a frameshift at residue 82; ribonuclease (pseudogene and partial)
257309008862	Predicted membrane protein [General function prediction only]; Region: COG4194
257309008863	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
257309008864	5 probable transmembrane helices predicted for DIP1677 by TMHMM2.0
257309008865	bifunctional RNase H/acid phosphatase; Provisional; Region: PRK07238
257309008866	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
257309008867	RNA/DNA hybrid binding site [nucleotide binding]; other site
257309008868	active site
257309008869	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309008870	catalytic core [active]
257309008871	HMMPfam hit to PF00300, Phosphoglycerate mutase
257309008872	HMMPfam hit to PF00075, RNase H
257309008873	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
257309008874	Putative zinc ribbon domain; Region: DUF164; pfam02591
257309008875	HMMPfam hit to PF02591, Uncharacterized ACR, COG1579
257309008876	Uncharacterized conserved protein [Function unknown]; Region: COG0327
257309008877	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
257309008878	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
257309008879	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
257309008880	HMMPfam hit to PF01784, Domain of unknown function DUF34
257309008881	hypothetical protein; Provisional; Region: PRK07908
257309008882	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309008883	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309008884	homodimer interface [polypeptide binding]; other site
257309008885	catalytic residue [active]
257309008886	HMMPfam hit to PF00155, Aminotransferase class I and II
257309008887	ScanRegExp hit to PS00105, Aminotransferases class-I pyridoxal-phosphate attachment site.
257309008888	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
257309008889	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309008890	motif II; other site
257309008891	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309008892	Low molecular weight phosphatase family; Region: LMWPc; cd00115
257309008893	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
257309008894	active site
257309008895	HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein phosphatase; HMMSmart hit to SM00226, Low molecular weight phosphatase
257309008896	FPrintScan hit to PR00719, LMW phosphotyrosine protein phosphatase signature
257309008897	FPrintScan hit to PR00719, LMW phosphotyrosine protein phosphatase signature
257309008898	FPrintScan hit to PR00719, LMW phosphotyrosine protein phosphatase signature
257309008899	FPrintScan hit to PR00719, LMW phosphotyrosine protein phosphatase signature
257309008900	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
257309008901	2 probable transmembrane helices predicted for DIP1684 by TMHMM2.0
257309008902	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
257309008903	ProfileScan hit to PS50310, Alanine-rich region.
257309008904	Protein of unknown function (DUF3052); Region: DUF3052; pfam11253
257309008905	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
257309008906	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
257309008907	dimer interface [polypeptide binding]; other site
257309008908	TPP-binding site [chemical binding]; other site
257309008909	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate binding domain
257309008910	Electron transfer DM13; Region: DM13; pfam10517
257309008911	1 probable transmembrane helix predicted for DIP1688 by TMHMM2.0
257309008912	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
257309008913	8 probable transmembrane helices predicted for DIP1689 by TMHMM2.0
257309008914	HMMPfam hit to PF01757, Domain of unknown function DUF33
257309008915	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
257309008916	9 probable transmembrane helices predicted for DIP1690 by TMHMM2.0
257309008917	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
257309008918	HMMPfam hit to PF00561, alpha/beta hydrolase fold
257309008919	FPrintScan hit to PR00412, Epoxide hydrolase signature
257309008920	FPrintScan hit to PR00412, Epoxide hydrolase signature
257309008921	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309008922	FPrintScan hit to PR00412, Epoxide hydrolase signature
257309008923	ScanRegExp hit to PS00120, Lipases, serine active site.
257309008924	FPrintScan hit to PR00412, Epoxide hydrolase signature
257309008925	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
257309008926	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309008927	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309008928	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
257309008929	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309008930	active site
257309008931	motif I; other site
257309008932	motif II; other site
257309008933	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309008934	motif II; other site
257309008935	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309008936	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309008937	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
257309008938	Beta-lactamase; Region: Beta-lactamase; pfam00144
257309008939	Predicted membrane protein [Function unknown]; Region: COG2860
257309008940	UPF0126 domain; Region: UPF0126; pfam03458
257309008941	UPF0126 domain; Region: UPF0126; pfam03458
257309008942	8 probable transmembrane helices predicted for DIP1696 by TMHMM2.0
257309008943	ScanRegExp hit to PS00687, Aldehyde dehydrogenases glutamic acid active site.
257309008944	DNA primase; Validated; Region: dnaG; PRK05667
257309008945	CHC2 zinc finger; Region: zf-CHC2; pfam01807
257309008946	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
257309008947	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
257309008948	active site
257309008949	metal binding site [ion binding]; metal-binding site
257309008950	interdomain interaction site; other site
257309008951	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
257309008952	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; smart00766
257309008953	HMMPfam hit to PF01751, Toprim domain
257309008954	HMMSmart hit to SM00493, No definition
257309008955	HMMPfam hit to PF01807, CHC2 zinc finger
257309008956	BlastProDom hit to PD002988, PD002988
257309008957	HMMSmart hit to SM00400, zinc finger
257309008958	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
257309008959	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
257309008960	glutaminase active site [active]
257309008961	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
257309008962	dimer interface [polypeptide binding]; other site
257309008963	active site
257309008964	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
257309008965	dimer interface [polypeptide binding]; other site
257309008966	active site
257309008967	HMMPfam hit to PF01380, SIS domain
257309008968	HMMPfam hit to PF01380, SIS domain
257309008969	HMMPfam hit to PF00310, Glutamine amidotransferases class-II
257309008970	ScanRegExp hit to PS00443, Glutamine amidotransferases class-II active site.
257309008971	RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate...; Region: RNase_Sa; cd00607
257309008972	active site
257309008973	barstar interaction site; other site
257309008974	1 probable transmembrane helix predicted for DIP1701 by TMHMM2.0
257309008975	HMMPfam hit to PF00545, ribonuclease.
257309008976	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK03007
257309008977	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
257309008978	Zn2+ binding site [ion binding]; other site
257309008979	Mg2+ binding site [ion binding]; other site
257309008980	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
257309008981	HMMSmart hit to SM00471, Metal dependent phosphohydrolases with conserved 'HD' motif.
257309008982	HMMPfam hit to PF01966, HD domain
257309008983	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
257309008984	putative active site [active]
257309008985	Repair protein; Region: Repair_PSII; pfam04536
257309008986	ProfileScan hit to PS50310, Alanine-rich region.
257309008987	ProfileScan hit to PS50315, Glycine-rich region.
257309008988	1 probable transmembrane helix predicted for DIP1707 by TMHMM2.0
257309008989	glycyl-tRNA synthetase; Provisional; Region: PRK04173
257309008990	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
257309008991	motif 1; other site
257309008992	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
257309008993	active site
257309008994	motif 2; other site
257309008995	motif 3; other site
257309008996	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
257309008997	anticodon binding site; other site
257309008998	HMMPfam hit to PF03129
257309008999	ScanRegExp hit to PS00307, Legume lectins beta-chain signature.
257309009000	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009001	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009002	HMMPfam hit to PF00587, tRNA synthetase class II (G, H, P, S and T)
257309009003	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009004	ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309009005	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009006	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009007	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009008	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009009	FPrintScan hit to PR01043, Glycyl-tRNA synthetase signature
257309009010	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
257309009011	putative DNA binding site [nucleotide binding]; other site
257309009012	dimerization interface [polypeptide binding]; other site
257309009013	putative Zn2+ binding site [ion binding]; other site
257309009014	HMMSmart hit to SM00418, helix_turn_helix, Arsenical Resistance Operon Repressor, DNA-binding
257309009015	HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family
257309009016	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309009017	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309009018	FPrintScan hit to PR00778, Bacterial regulatory protein ArsR family signature
257309009019	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
257309009020	metal binding site 2 [ion binding]; metal-binding site
257309009021	putative DNA binding helix; other site
257309009022	metal binding site 1 [ion binding]; metal-binding site
257309009023	dimer interface [polypeptide binding]; other site
257309009024	structural Zn2+ binding site [ion binding]; other site
257309009025	HMMPfam hit to PF01475, Ferric uptake regulator family
257309009026	BlastProDom hit to PD002003, PD002003
257309009027	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
257309009028	diiron binding motif [ion binding]; other site
257309009029	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_2; cd02433
257309009030	4 probable transmembrane helices predicted for DIP1711 by TMHMM2.0
257309009031	HMMPfam hit to PF01988, Integral membrane protein DUF125
257309009032	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
257309009033	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
257309009034	catalytic residue [active]
257309009035	putative FPP diphosphate  binding site; other site
257309009036	putative FPP binding hydrophobic cleft; other site
257309009037	dimer interface [polypeptide binding]; other site
257309009038	putative IPP diphosphate binding site; other site
257309009039	HMMPfam hit to PF01255,  undecaprenyl diphosphate synthase
257309009040	BlastProDom hit to PD003461, PD003461
257309009041	Recombination protein O N terminal; Region: RecO_N; pfam11967
257309009042	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
257309009043	Recombination protein O C terminal; Region: RecO_C; pfam02565
257309009044	HMMPfam hit to PF02565, Recombination protein O
257309009045	GTPase Era; Reviewed; Region: era; PRK00089
257309009046	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
257309009047	G1 box; other site
257309009048	GTP/Mg2+ binding site [chemical binding]; other site
257309009049	Switch I region; other site
257309009050	G2 box; other site
257309009051	Switch II region; other site
257309009052	G3 box; other site
257309009053	G4 box; other site
257309009054	G5 box; other site
257309009055	KH domain; Region: KH_2; pfam07650
257309009056	ProfileScan hit to PS50823, Type-2 KH domain profile.
257309009057	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309009058	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309009059	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009060	pyridoxamine kinase; Validated; Region: PRK05756
257309009061	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
257309009062	dimer interface [polypeptide binding]; other site
257309009063	pyridoxal binding site [chemical binding]; other site
257309009064	ATP binding site [chemical binding]; other site
257309009065	HMMPfam hit to PF00294, pfkB family carbohydrate kinase
257309009066	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
257309009067	Domain of unknown function DUF21; Region: DUF21; pfam01595
257309009068	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
257309009069	Transporter associated domain; Region: CorC_HlyC; smart01091
257309009070	HMMPfam hit to PF00571, CBS domain
257309009071	ProfileScan hit to PS50147, SNF4 repeat.
257309009072	HMMPfam hit to PF00571, CBS domain
257309009073	ProfileScan hit to PS50147, SNF4 repeat.
257309009074	HMMPfam hit to PF01595, Domain of unknown function DUF21
257309009075	4 probable transmembrane helices predicted for DIP1716 by TMHMM2.0
257309009076	metal-binding heat shock protein; Provisional; Region: PRK00016
257309009077	HMMPfam hit to PF02130, Uncharacterized protein family UPF0054
257309009078	BlastProDom hit to PD005688, PD005688
257309009079	ScanRegExp hit to PS01306, Uncharacterized protein family UPF0054 signature.
257309009080	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
257309009081	PhoH-like protein; Region: PhoH; pfam02562
257309009082	HMMPfam hit to PF02562, PhoH-like protein
257309009083	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009084	RNA methyltransferase, RsmE family; Region: TIGR00046
257309009085	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
257309009086	chaperone protein DnaJ; Provisional; Region: PRK14278
257309009087	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
257309009088	HSP70 interaction site [polypeptide binding]; other site
257309009089	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
257309009090	Zn binding sites [ion binding]; other site
257309009091	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
257309009092	dimer interface [polypeptide binding]; other site
257309009093	HMMPfam hit to PF01556, DnaJ C terminal region
257309009094	FPrintScan hit to PR00625, DnaJ protein family signature
257309009095	FPrintScan hit to PR00625, DnaJ protein family signature
257309009096	HMMPfam hit to PF00684, DnaJ central domain (4 repeats)
257309009097	FPrintScan hit to PR00625, DnaJ protein family signature
257309009098	FPrintScan hit to PR00625, DnaJ protein family signature
257309009099	FPrintScan hit to PR00625, DnaJ protein family signature
257309009100	ScanRegExp hit to PS00637, CXXCXGXG dnaJ domain signature.
257309009101	FPrintScan hit to PR00625, DnaJ protein family signature
257309009102	ProfileScan hit to PS50315, Glycine-rich region.
257309009103	HMMPfam hit to PF00226, DnaJ domain; ProfileScan hit to PS50076, dnaJ domain profile.
257309009104	FPrintScan hit to PR00625, DnaJ protein family signature
257309009105	HMMSmart hit to SM00271, DnaJ molecular chaperone homology domain
257309009106	FPrintScan hit to PR00625, DnaJ protein family signature
257309009107	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
257309009108	HMMPfam hit to PF01628, HrcA protein
257309009109	coproporphyrinogen III oxidase; Validated; Region: PRK05628
257309009110	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
257309009111	FeS/SAM binding site; other site
257309009112	HemN C-terminal domain; Region: HemN_C; pfam06969
257309009113	HMMPfam hit to PF02473, Oxygen-independent Coproporphyrinogen III oxidase
257309009114	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309009115	putative ABC transporter-associated repeat protein; Region: anch_rpt_wall; TIGR03773
257309009116	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309009117	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309009118	1 probable transmembrane helix predicted for DIP1724 by TMHMM2.0
257309009119	potential sortase anchor site LANTG
257309009120	Potential twin-arginine recognition motif RRVFAS
257309009121	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
257309009122	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
257309009123	acyl-activating enzyme (AAE) consensus motif; other site
257309009124	putative AMP binding site [chemical binding]; other site
257309009125	putative active site [active]
257309009126	putative CoA binding site [chemical binding]; other site
257309009127	Predicted helix-turn-helix motif with score 1057 (+2.79 SD) at aa 545-566, sequence VLRAEIQDAINLANSTVSHAEA
257309009128	HMMPfam hit to PF00501, AMP-binding enzyme
257309009129	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309009130	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
257309009131	HMMPfam hit to PF02446, 4-alpha-glucanotransferase
257309009132	1 probable transmembrane helix predicted for DIP1727 by TMHMM2.0
257309009133	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
257309009134	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
257309009135	active site
257309009136	Zn binding site [ion binding]; other site
257309009137	HMMPfam hit to PF01432, Peptidase M3
257309009138	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309009139	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
257309009140	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
257309009141	substrate binding pocket [chemical binding]; other site
257309009142	HMMPfam hit to PF00135, Carboxylesterase
257309009143	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309009144	ScanRegExp hit to PS00122, Carboxylesterases type-B serine active site.
257309009145	Predicted helix-turn-helix motif with score 1047 (+2.75 SD) at aa 254-275, sequence YTTDECADFVGVKKLQASRWSK
257309009146	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
257309009147	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
257309009148	active site
257309009149	metal binding site [ion binding]; metal-binding site
257309009150	nudix motif; other site
257309009151	HMMPfam hit to PF00293, MutT-like domain
257309009152	BlastProDom hit to PD004109, PD004109
257309009153	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009154	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009155	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309009156	active site
257309009157	HMMPfam hit to PF01844, HNH endonuclease
257309009158	HMMSmart hit to SM00507, HNH nucleases
257309009159	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309009160	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309009161	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309009162	Walker A/P-loop; other site
257309009163	ATP binding site [chemical binding]; other site
257309009164	Q-loop/lid; other site
257309009165	ABC transporter signature motif; other site
257309009166	Walker B; other site
257309009167	D-loop; other site
257309009168	H-loop/switch region; other site
257309009169	5 probable transmembrane helices predicted for DIP1735 by TMHMM2.0
257309009170	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309009171	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009172	HMMPfam hit to PF00005, ABC transporter
257309009173	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309009174	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009175	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309009176	ScanRegExp hit to PS00211, ABC transporters family signature.
257309009177	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
257309009178	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309009179	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309009180	homodimer interface [polypeptide binding]; other site
257309009181	catalytic residue [active]
257309009182	HMMPfam hit to PF00155, Aminotransferase class I and II
257309009183	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309009184	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309009185	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309009186	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
257309009187	12 probable transmembrane helices predicted for DIP1737 by TMHMM2.0
257309009188	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
257309009189	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
257309009190	HMMPfam hit to PF00296, Luciferase-like monooxygenase
257309009191	BCCT family transporter; Region: BCCT; pfam02028
257309009192	BlastProDom hit to PD010111, PD010111
257309009193	HMMPfam hit to PF02028, BCCT family transporter
257309009194	13 probable transmembrane helices predicted for DIP1739 by TMHMM2.0
257309009195	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
257309009196	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_6; cd08494
257309009197	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309009198	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
257309009199	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309009200	dimer interface [polypeptide binding]; other site
257309009201	conserved gate region; other site
257309009202	putative PBP binding loops; other site
257309009203	ABC-ATPase subunit interface; other site
257309009204	6 probable transmembrane helices predicted for DIP1741 by TMHMM2.0
257309009205	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309009206	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309009207	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
257309009208	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309009209	dimer interface [polypeptide binding]; other site
257309009210	conserved gate region; other site
257309009211	putative PBP binding loops; other site
257309009212	ABC-ATPase subunit interface; other site
257309009213	5 probable transmembrane helices predicted for DIP1742 by TMHMM2.0
257309009214	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309009215	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
257309009216	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309009217	Walker A/P-loop; other site
257309009218	ATP binding site [chemical binding]; other site
257309009219	Q-loop/lid; other site
257309009220	ABC transporter signature motif; other site
257309009221	Walker B; other site
257309009222	D-loop; other site
257309009223	H-loop/switch region; other site
257309009224	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
257309009225	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309009226	Walker A/P-loop; other site
257309009227	ATP binding site [chemical binding]; other site
257309009228	Q-loop/lid; other site
257309009229	ABC transporter signature motif; other site
257309009230	Walker B; other site
257309009231	D-loop; other site
257309009232	H-loop/switch region; other site
257309009233	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
257309009234	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009235	HMMPfam hit to PF00005, ABC transporter
257309009236	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009237	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309009238	ScanRegExp hit to PS00211, ABC transporters family signature.
257309009239	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009240	HMMPfam hit to PF00005, ABC transporter
257309009241	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309009242	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009243	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309009244	ScanRegExp hit to PS00211, ABC transporters family signature.
257309009245	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
257309009246	HMMPfam hit to PF00561, alpha/beta hydrolase fold
257309009247	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309009248	FPrintScan hit to PR00793, Prolyl aminopeptidase (S33) family signature
257309009249	FPrintScan hit to PR00793, Prolyl aminopeptidase (S33) family signature
257309009250	FPrintScan hit to PR00793, Prolyl aminopeptidase (S33) family signature
257309009251	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
257309009252	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
257309009253	catalytic residue [active]
257309009254	HMMPfam hit to PF01168, Uncharacterized protein family UPF0001
257309009255	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
257309009256	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
257309009257	nucleotide binding site [chemical binding]; other site
257309009258	HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-terminal domain
257309009259	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309009260	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
257309009261	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
257309009262	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
257309009263	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
257309009264	active site residue [active]
257309009265	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase
257309009266	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309009267	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309009268	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature
257309009269	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309009270	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309009271	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309009272	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309009273	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309009274	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
257309009275	FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309009276	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309009277	HMMPfam hit to PF00581, Rhodanese-like domain
257309009278	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309009279	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
257309009280	putative homodimer interface [polypeptide binding]; other site
257309009281	putative homotetramer interface [polypeptide binding]; other site
257309009282	putative allosteric switch controlling residues; other site
257309009283	putative metal binding site [ion binding]; other site
257309009284	putative homodimer-homodimer interface [polypeptide binding]; other site
257309009285	HMMPfam hit to PF02583, Uncharacterized BCR, COG1937
257309009286	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
257309009287	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
257309009288	TrkA-N domain; Region: TrkA_N; pfam02254
257309009289	HMMPfam hit to PF02254, KTN NAD-binding domain
257309009290	8 probable transmembrane helices predicted for DIP1750 by TMHMM2.0
257309009291	HMMPfam hit to PF00999, Sodium/hydrogen exchanger family
257309009292	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
257309009293	2 probable transmembrane helices predicted for DIP1751 by TMHMM2.0
257309009294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309009295	14 probable transmembrane helices predicted for DIP1752 by TMHMM2.0
257309009296	HMMPfam hit to PF00083, Sugar (and other) transporter
257309009297	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
257309009298	active site
257309009299	tetramer interface [polypeptide binding]; other site
257309009300	HMMPfam hit to PF01156, Inosine-uridine preferring nucleoside hydrolase
257309009301	BlastProDom hit to PD007736, PD007736
257309009302	ScanRegExp hit to PS01247, Inosine-uridine preferring nucleoside hydrolase signature.
257309009303	9 probable transmembrane helices predicted for DIP1754 by TMHMM2.0
257309009304	6 probable transmembrane helices predicted for DIP1755 by TMHMM2.0
257309009305	ScanRegExp hit to PS00284, Serpins signature.
257309009306	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
257309009307	Methyltransferase domain; Region: Methyltransf_26; pfam13659
257309009308	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309009309	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309009310	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309009311	Mrr N-terminal domain; Region: Mrr_N; pfam14338
257309009312	Restriction endonuclease; Region: Mrr_cat; pfam04471
257309009313	1 probable transmembrane helix predicted for DIP1757 by TMHMM2.0
257309009314	Abi-like protein; Region: Abi_2; pfam07751
257309009315	AAA ATPase domain; Region: AAA_16; pfam13191
257309009316	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009317	GTP-binding protein LepA; Provisional; Region: PRK05433
257309009318	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
257309009319	G1 box; other site
257309009320	putative GEF interaction site [polypeptide binding]; other site
257309009321	GTP/Mg2+ binding site [chemical binding]; other site
257309009322	Switch I region; other site
257309009323	G2 box; other site
257309009324	G3 box; other site
257309009325	Switch II region; other site
257309009326	G4 box; other site
257309009327	G5 box; other site
257309009328	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
257309009329	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
257309009330	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
257309009331	HMMPfam hit to PF03144
257309009332	HMMPfam hit to PF00009, Elongation factor Tu family
257309009333	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309009334	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309009335	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309009336	ScanRegExp hit to PS00301, GTP-binding elongation factors signature.
257309009337	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309009338	FPrintScan hit to PR00315, GTP-binding elongation factor signature
257309009339	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009340	PemK-like protein; Region: PemK; pfam02452
257309009341	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
257309009342	BlastProDom hit to PD004231, PD004231; HMMPfam hit to PF01649, Ribosomal protein S20
257309009343	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
257309009344	6 probable transmembrane helices predicted for DIP1767 by TMHMM2.0
257309009345	ProfileScan hit to PS50282, Bacterial transmembrane transporters, lysE/yggA family.
257309009346	HMMPfam hit to PF01810, LysE type translocator
257309009347	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
257309009348	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
257309009349	ProfileScan hit to PS50297, Ankyrin repeat region circular profile.
257309009350	HMMPfam hit to PF00023, Ank repeat; ProfileScan hit to PS50088, Ankyrin repeat profile.
257309009351	HMMSmart hit to SM00248, ankyrin repeats
257309009352	HMMPfam hit to PF00023, Ank repeat; ProfileScan hit to PS50088, Ankyrin repeat profile.
257309009353	HMMSmart hit to SM00248, ankyrin repeats
257309009354	HMMSmart hit to SM00248, ankyrin repeats
257309009355	hypothetical protein; Validated; Region: PRK05629
257309009356	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
257309009357	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
257309009358	Competence protein; Region: Competence; pfam03772
257309009359	9 probable transmembrane helices predicted for DIP1770 by TMHMM2.0
257309009360	comEA protein; Region: comE; TIGR01259
257309009361	Helix-hairpin-helix motif; Region: HHH; pfam00633
257309009362	helix-hairpin-helix signature motif; other site
257309009363	ProfileScan hit to PS50120, Helix-hairpin-helix motif.
257309009364	HMMSmart hit to SM00278, Helix-hairpin-helix DNA-binding motif class 1
257309009365	ProfileScan hit to PS50120, Helix-hairpin-helix motif.
257309009366	HMMSmart hit to SM00278, Helix-hairpin-helix DNA-binding motif class 1
257309009367	1 probable transmembrane helix predicted for DIP1771 by TMHMM2.0
257309009368	EDD domain protein, DegV family; Region: DegV; TIGR00762
257309009369	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
257309009370	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307
257309009371	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309009372	catalytic core [active]
257309009373	HMMPfam hit to PF00300, Phosphoglycerate mutase
257309009374	ScanRegExp hit to PS00175, Phosphoglycerate mutase phosphohistidine signature.
257309009375	Oligomerisation domain; Region: Oligomerisation; cl00519
257309009376	HMMPfam hit to PF02410, Domain of unknown function DUF143
257309009377	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
257309009378	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
257309009379	active site
257309009380	(T/H)XGH motif; other site
257309009381	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
257309009382	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
257309009383	putative catalytic cysteine [active]
257309009384	HMMPfam hit to PF00171, Aldehyde dehydrogenase
257309009385	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009386	gamma-glutamyl kinase; Provisional; Region: PRK05429
257309009387	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
257309009388	nucleotide binding site [chemical binding]; other site
257309009389	homotetrameric interface [polypeptide binding]; other site
257309009390	putative phosphate binding site [ion binding]; other site
257309009391	putative allosteric binding site; other site
257309009392	PUA domain; Region: PUA; pfam01472
257309009393	HMMSmart hit to SM00359,  RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase
257309009394	HMMPfam hit to PF01472, PUA domain
257309009395	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309009396	HMMPfam hit to PF00696, Amino acid kinase
257309009397	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309009398	ScanRegExp hit to PS00902, Glutamate 5-kinase signature.
257309009399	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309009400	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309009401	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309009402	FPrintScan hit to PR00474, Glutamate 5-kinase signature
257309009403	3 probable transmembrane helices predicted for DIP1778 by TMHMM2.0
257309009404	GTPase CgtA; Reviewed; Region: obgE; PRK12296
257309009405	GTP1/OBG; Region: GTP1_OBG; pfam01018
257309009406	Obg GTPase; Region: Obg; cd01898
257309009407	G1 box; other site
257309009408	GTP/Mg2+ binding site [chemical binding]; other site
257309009409	Switch I region; other site
257309009410	G2 box; other site
257309009411	G3 box; other site
257309009412	Switch II region; other site
257309009413	G4 box; other site
257309009414	G5 box; other site
257309009415	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
257309009416	HMMPfam hit to PF01018, GTP1/OBG family
257309009417	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309009418	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309009419	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309009420	FPrintScan hit to PR00326, GTP1/OBG GTP-binding protein family signature
257309009421	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009422	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
257309009423	BlastProDom hit to PD003114, PD003114; HMMPfam hit to PF01016, Ribosomal L27 protein
257309009424	FPrintScan hit to PR00063, Ribosomal protein L27 signature
257309009425	FPrintScan hit to PR00063, Ribosomal protein L27 signature
257309009426	ScanRegExp hit to PS00831, Ribosomal protein L27 signature.
257309009427	FPrintScan hit to PR00063, Ribosomal protein L27 signature
257309009428	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
257309009429	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
257309009430	HMMPfam hit to PF00829, Ribosomal prokaryotic L21 protein
257309009431	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
257309009432	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
257309009433	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
257309009434	homodimer interface [polypeptide binding]; other site
257309009435	oligonucleotide binding site [chemical binding]; other site
257309009436	HMMPfam hit to PF00575, S1 RNA binding domain
257309009437	HMMSmart hit to SM00316, Ribosomal protein S1-like RNA-binding domain
257309009438	ProfileScan hit to PS50126, S1-motif (ribosomal).
257309009439	ProfileScan hit to PS50313, Glutamic acid-rich region.
257309009440	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
257309009441	active site
257309009442	multimer interface [polypeptide binding]; other site
257309009443	HMMPfam hit to PF00334, Nucleoside diphosphate kinase
257309009444	BlastProDom hit to PD001018, PD001018
257309009445	FPrintScan hit to PR01243, Nucleoside diphosphate kinase signature
257309009446	ScanRegExp hit to PS00469, Nucleoside diphosphate kinases active site.
257309009447	FPrintScan hit to PR01243, Nucleoside diphosphate kinase signature
257309009448	FPrintScan hit to PR01243, Nucleoside diphosphate kinase signature
257309009449	FPrintScan hit to PR01243, Nucleoside diphosphate kinase signature
257309009450	FPrintScan hit to PR01243, Nucleoside diphosphate kinase signature
257309009451	Protein of unknown function (DUF4233); Region: DUF4233; pfam14017
257309009452	3 probable transmembrane helices predicted for DIP1784 by TMHMM2.0
257309009453	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
257309009454	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
257309009455	HMMPfam hit to PF02875, Mur ligase, glutamate ligase domain
257309009456	HMMPfam hit to PF01225, Mur ligase, catalytic domain
257309009457	ScanRegExp hit to PS01012, Folylpolyglutamate synthase signature 2.
257309009458	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
257309009459	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309009460	active site
257309009461	HIGH motif; other site
257309009462	nucleotide binding site [chemical binding]; other site
257309009463	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
257309009464	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
257309009465	active site
257309009466	KMSKS motif; other site
257309009467	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
257309009468	tRNA binding surface [nucleotide binding]; other site
257309009469	anticodon binding site; other site
257309009470	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
257309009471	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V)
257309009472	FPrintScan hit to PR00986, Valyl-tRNA synthetase signature
257309009473	FPrintScan hit to PR00986, Valyl-tRNA synthetase signature
257309009474	FPrintScan hit to PR00986, Valyl-tRNA synthetase signature
257309009475	FPrintScan hit to PR00986, Valyl-tRNA synthetase signature
257309009476	ScanRegExp hit to PS00178, Aminoacyl-transfer RNA synthetases class-I signature.
257309009477	FPrintScan hit to PR00986, Valyl-tRNA synthetase signature
257309009478	malate dehydrogenase; Provisional; Region: PRK05442
257309009479	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
257309009480	NAD(P) binding site [chemical binding]; other site
257309009481	dimer interface [polypeptide binding]; other site
257309009482	malate binding site [chemical binding]; other site
257309009483	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-terminal domain
257309009484	BlastProDom hit to PD003052, PD003052
257309009485	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding domain
257309009486	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309009487	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309009488	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309009489	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309009490	Predicted helix-turn-helix motif with score 1372 (+3.86 SD) at aa 38-59, sequence AKLEAIAKKSGMSKRMIHYHFG
257309009491	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309009492	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
257309009493	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
257309009494	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
257309009495	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309009496	Walker A motif; other site
257309009497	ATP binding site [chemical binding]; other site
257309009498	Walker B motif; other site
257309009499	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
257309009500	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309009501	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009502	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309009503	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009504	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
257309009505	Glutamine amidotransferase class-I; Region: GATase; pfam00117
257309009506	glutamine binding [chemical binding]; other site
257309009507	catalytic triad [active]
257309009508	aminodeoxychorismate synthase, component I, clade 2; Region: PabB-clade2; TIGR01824
257309009509	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
257309009510	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
257309009511	substrate-cofactor binding pocket; other site
257309009512	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309009513	BlastProDom hit to PD000779, PD000779
257309009514	HMMPfam hit to PF00425, chorismate binding enzyme
257309009515	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309009516	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309009517	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309009518	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309009519	HMMPfam hit to PF00117, Glutamine amidotransferase class-I
257309009520	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309009521	ScanRegExp hit to PS00063, Aldo/keto reductase active site signature.
257309009522	FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309009523	FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309009524	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309009525	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature; ScanRegExp hit to PS00442, Glutamine amidotransferases class-I active site.
257309009526	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309009527	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309009528	FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309009529	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
257309009530	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
257309009531	oligomer interface [polypeptide binding]; other site
257309009532	active site residues [active]
257309009533	HMMPfam hit to PF00574, Clp protease
257309009534	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009535	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009536	ScanRegExp hit to PS00382, Endopeptidase Clp histidine active site.
257309009537	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009538	ScanRegExp hit to PS00381, Endopeptidase Clp serine active site.
257309009539	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009540	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009541	Clp protease; Region: CLP_protease; pfam00574
257309009542	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
257309009543	oligomer interface [polypeptide binding]; other site
257309009544	active site residues [active]
257309009545	HMMPfam hit to PF00574, Clp protease
257309009546	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009547	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009548	ScanRegExp hit to PS00382, Endopeptidase Clp histidine active site.
257309009549	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009550	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009551	FPrintScan hit to PR00127, Clp protease catalytic subunit P signature
257309009552	trigger factor; Provisional; Region: tig; PRK01490
257309009553	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
257309009554	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
257309009555	ProfileScan hit to PS50059, FKBP-type peptidyl-prolyl cis-trans isomerase domain profile.
257309009556	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomerase
257309009557	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
257309009558	HMMPfam hit to PF02502, Ribose/Galactose Isomerase
257309009559	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
257309009560	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
257309009561	catalytic residues [active]
257309009562	aminopeptidase N, Streptomyces lividans type; Region: pepN_strep_liv; TIGR02412
257309009563	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_3; cd09602
257309009564	Zn binding site [ion binding]; other site
257309009565	HMMPfam hit to PF01433, Peptidase M1
257309009566	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309009567	HMMPfam hit to PF01433, Peptidase M1
257309009568	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309009569	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309009570	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309009571	FPrintScan hit to PR00756, Membrane alanyl dipeptidase (M1) family signature
257309009572	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
257309009573	Mechanosensitive ion channel; Region: MS_channel; pfam00924
257309009574	3 probable transmembrane helices predicted for DIP1799 by TMHMM2.0
257309009575	HMMPfam hit to PF00924, Mechanosensitive ion channel
257309009576	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
257309009577	apolar tunnel; other site
257309009578	heme binding site [chemical binding]; other site
257309009579	dimerization interface [polypeptide binding]; other site
257309009580	HMMPfam hit to PF01152, Protozoan/cyanobacterial globin
257309009581	BlastProDom hit to PD004840, PD004840
257309009582	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
257309009583	active site
257309009584	HMMPfam hit to PF03061
257309009585	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
257309009586	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309009587	Walker A/P-loop; other site
257309009588	ATP binding site [chemical binding]; other site
257309009589	Q-loop/lid; other site
257309009590	ABC transporter signature motif; other site
257309009591	Walker B; other site
257309009592	D-loop; other site
257309009593	H-loop/switch region; other site
257309009594	ABC transporter; Region: ABC_tran_2; pfam12848
257309009595	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
257309009596	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009597	HMMPfam hit to PF00005, ABC transporter
257309009598	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309009599	ScanRegExp hit to PS00211, ABC transporters family signature.
257309009600	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309009601	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009602	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009603	HMMPfam hit to PF00005, ABC transporter
257309009604	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309009605	ScanRegExp hit to PS00211, ABC transporters family signature.
257309009606	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309009607	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009608	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
257309009609	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
257309009610	dimer interface [polypeptide binding]; other site
257309009611	ssDNA binding site [nucleotide binding]; other site
257309009612	tetramer (dimer of dimers) interface [polypeptide binding]; other site
257309009613	HMMPfam hit to PF00436, Single-strand binding protein family
257309009614	Copper resistance protein D; Region: CopD; pfam05425
257309009615	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
257309009616	16 probable transmembrane helices predicted for DIP1805 by TMHMM2.0
257309009617	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
257309009618	Carbon starvation protein CstA; Region: CstA; pfam02554
257309009619	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
257309009620	15 probable transmembrane helices predicted for DIP1806 by TMHMM2.0
257309009621	HMMPfam hit to PF02554, Carbon starvation protein CstA
257309009622	Protein of unknown function (DUF466); Region: DUF466; pfam04328
257309009623	Homeodomain-like domain; Region: HTH_23; cl17451
257309009624	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309009625	Predicted helix-turn-helix motif with score 1129 (+3.03 SD) at aa 23-44, sequence YGSRAVANRLGVRREQVRHLED
257309009626	putative transposase OrfB; Reviewed; Region: PHA02517
257309009627	HTH-like domain; Region: HTH_21; pfam13276
257309009628	Integrase core domain; Region: rve; pfam00665
257309009629	Integrase core domain; Region: rve_2; pfam13333
257309009630	HMMPfam hit to PF00665, Integrase core domain
257309009631	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309009632	Major Facilitator Superfamily; Region: MFS_1; pfam07690
257309009633	putative substrate translocation pore; other site
257309009634	9 probable transmembrane helices predicted for DIP1810 by TMHMM2.0
257309009635	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
257309009636	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
257309009637	NADP binding site [chemical binding]; other site
257309009638	dimer interface [polypeptide binding]; other site
257309009639	HMMPfam hit to PF00107, Zinc-binding dehydrogenases
257309009640	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
257309009641	classical (c) SDRs; Region: SDR_c; cd05233
257309009642	NAD(P) binding site [chemical binding]; other site
257309009643	active site
257309009644	HMMPfam hit to PF00106, short chain dehydrogenase
257309009645	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309009646	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309009647	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature; FPrintScan hit to PR00080, Short-chain dehydrogenase/reductase (SDR) superfamily signature
257309009648	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309009649	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309009650	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309009651	FPrintScan hit to PR00080, Short-chain dehydrogenase/reductase (SDR) superfamily signature
257309009652	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature; FPrintScan hit to PR00080, Short-chain dehydrogenase/reductase (SDR) superfamily signature
257309009653	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309009654	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309009655	1 probable transmembrane helix predicted for DIP1812 by TMHMM2.0
257309009656	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
257309009657	catalytic site [active]
257309009658	putative active site [active]
257309009659	putative substrate binding site [chemical binding]; other site
257309009660	dimer interface [polypeptide binding]; other site
257309009661	HMMSmart hit to SM00479, No definition
257309009662	HMMPfam hit to PF00929, Exonuclease
257309009663	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
257309009664	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
257309009665	inhibitor site; inhibition site
257309009666	active site
257309009667	dimer interface [polypeptide binding]; other site
257309009668	catalytic residue [active]
257309009669	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase
257309009670	BlastProDom hit to PD001859, PD001859
257309009671	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309009672	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309009673	FPrintScan hit to PR00146, Dihydrodipicolinate synthase signature
257309009674	IgD-like repeat domain of mycobacterial L,D-transpeptidases; Region: LDT_IgD_like; cl17506
257309009675	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
257309009676	IgD-like repeat domain of mycobacterial L,D-transpeptidases; Region: LDT_IgD_like_2; cd13432
257309009677	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
257309009678	1 probable transmembrane helix predicted for DIP1816 by TMHMM2.0
257309009679	Anomalous G+C content (55.15%) and dinucleotide signature.  prophage related pathogenicity island. Not present in C.glutamicum
257309009680	Helix-turn-helix domain; Region: HTH_17; pfam12728
257309009681	Predicted helix-turn-helix motif with score 1744 (+5.13 SD) at aa 25-46, sequence LTTKEVAARLGIAKSTVTKRVR
257309009682	1 probable transmembrane helix predicted for DIP1820 by TMHMM2.0
257309009683	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309009684	active site
257309009685	HMMSmart hit to SM00507, HNH nucleases
257309009686	HMMPfam hit to PF01844, HNH endonuclease
257309009687	Phage Terminase; Region: Terminase_1; pfam03354
257309009688	ProfileScan hit to PS50310, Alanine-rich region.
257309009689	ScanRegExp hit to PS00339, Aminoacyl-transfer RNA synthetases class-II signature 2.
257309009690	Phage portal protein; Region: Phage_portal; pfam04860
257309009691	Phage-related protein [Function unknown]; Region: COG4695; cl01923
257309009692	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
257309009693	ProfileScan hit to PS50310, Alanine-rich region.
257309009694	2 probable transmembrane helices predicted for DIP1834 by TMHMM2.0
257309009695	ProfileScan hit to PS50310, Alanine-rich region.
257309009696	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009697	ProfileScan hit to PS50288, Collagen repeat (G-x-x), circular profile.
257309009698	ProfileScan hit to PS50099, Proline-rich region.
257309009699	ProfileScan hit to PS50315, Glycine-rich region.
257309009700	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies)
257309009701	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
257309009702	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
257309009703	active site
257309009704	DNA binding site [nucleotide binding]
257309009705	Int/Topo IB signature motif; other site
257309009706	HMMPfam hit to PF00589, Phage integrase
257309009707	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like domain
257309009708	1 probable transmembrane helix predicted for DIP1838 by TMHMM2.0
257309009709	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
257309009710	conserved cis-peptide bond; other site
257309009711	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
257309009712	Protein of unknown function (DUF3618); Region: DUF3618; pfam12277
257309009713	1 probable transmembrane helix predicted for DIP1842 by TMHMM2.0
257309009714	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
257309009715	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
257309009716	catalytic triad [active]
257309009717	HMMPfam hit to PF00578, AhpC/TSA family
257309009718	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309009719	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309009720	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309009721	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309009722	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309009723	Predicted helix-turn-helix motif with score 1599 (+4.63 SD) at aa 45-66, sequence FTFDEVAKRAEVPIGTIYQYFA
257309009724	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309009725	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
257309009726	ScanRegExp hit to PS00294, Prenyl group binding site (CAAX box).
257309009727	BlastProDom hit to PD004282, PD004282
257309009728	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfamily
257309009729	Predicted helix-turn-helix motif with score 1126 (+3.02 SD) at aa 95-116, sequence VPRGEVARACGIECAQVSISHD
257309009730	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
257309009731	Enoyl reductase domain of yeast-type FAS1 [Lipid metabolism]; Region: COG4981
257309009732	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
257309009733	phosphate binding site [ion binding]; other site
257309009734	Domain of unknown function (DUF1729); Region: DUF1729; pfam08354
257309009735	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
257309009736	active site 2 [active]
257309009737	active site 1 [active]
257309009738	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
257309009739	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
257309009740	3-oxoacyl-[acyl-carrier protein]; Region: COG4982
257309009741	ketoacyl reductase (KR) domain of fungal-type fatty acid synthase (fFAS), classical (c)-like SDRs; Region: KR_fFAS_SDR_c_like; cd08950
257309009742	putative NAD(P) binding site [chemical binding]; other site
257309009743	active site
257309009744	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
257309009745	"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP)...; Region: elong_cond_enzymes; cd00828
257309009746	active site
257309009747	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal domain
257309009748	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal domain
257309009749	ScanRegExp hit to PS00606, Beta-ketoacyl synthases active site.
257309009750	HMMPfam hit to PF00698, Acyl transferase domain
257309009751	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009752	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009753	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009754	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009755	HMMPfam hit to PF01575, MaoC like domain
257309009756	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009757	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009758	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009759	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009760	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009761	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009762	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009763	FPrintScan hit to PR01483, Fatty acid synthase signature
257309009764	Glucitol operon activator protein (GutM); Region: GutM; cl01890
257309009765	2 probable transmembrane helices predicted for DIP1848 by TMHMM2.0
257309009766	Domain of unknown function (DUF3817); Region: DUF3817; pfam12823
257309009767	3 probable transmembrane helices predicted for DIP1849 by TMHMM2.0
257309009768	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
257309009769	active site
257309009770	dimerization interface [polypeptide binding]; other site
257309009771	HMMPfam hit to PF01725, Ham1 family
257309009772	BlastProDom hit to PD004952, PD004952
257309009773	ribonuclease PH; Reviewed; Region: rph; PRK00173
257309009774	Ribonuclease PH; Region: RNase_PH_bact; cd11362
257309009775	hexamer interface [polypeptide binding]; other site
257309009776	active site
257309009777	HMMPfam hit to PF01138, 3' exoribonuclease
257309009778	ScanRegExp hit to PS01277, Ribonuclease PH signature.
257309009779	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
257309009780	glutamate racemase; Provisional; Region: PRK00865
257309009781	HMMPfam hit to PF01177, Asp/Glu/Hydontoin racemase
257309009782	ScanRegExp hit to PS00924, Aspartate and glutamate racemases signature 2.
257309009783	ScanRegExp hit to PS00923, Aspartate and glutamate racemases signature 1.
257309009784	Rhomboid family; Region: Rhomboid; cl11446
257309009785	HMMPfam hit to PF01694, Rhomboid family
257309009786	ScanRegExp hit to PS00485, Adenosine and AMP deaminase signature.
257309009787	6 probable transmembrane helices predicted for DIP1854 by TMHMM2.0
257309009788	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252
257309009789	putative active site pocket [active]
257309009790	cleavage site
257309009791	Domain of unknown function (DUF2017); Region: DUF2017; pfam09438
257309009792	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
257309009793	HMMPfam hit to PF02617, Uncharacterized ACR, COG2127
257309009794	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
257309009795	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
257309009796	active site
257309009797	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
257309009798	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
257309009799	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309009800	putative Mg++ binding site [ion binding]; other site
257309009801	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
257309009802	HMMPfam hit to PF00270, DEAD/DEAH box helicase
257309009803	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309009804	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009805	HMMSmart hit to SM00491, No definition
257309009806	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009807	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
257309009808	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
257309009809	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309009810	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309009811	active site
257309009812	HMMSmart hit to SM00507, HNH nucleases
257309009813	HMMPfam hit to PF01844, HNH endonuclease
257309009814	Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported to encode such activity, Pth present in...; Region: PTH2_family; cl00869
257309009815	dimer interface [polypeptide binding]; other site
257309009816	putative active site [active]
257309009817	HMMPfam hit to PF01981, Domain of unknown function UPF0099
257309009818	Glycine cleavage system regulatory protein [Amino acid transport and metabolism]; Region: GcvR; COG2716
257309009819	CT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_1; cd04870
257309009820	ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_2; cd04871
257309009821	phosphoserine phosphatase SerB; Region: serB; TIGR00338
257309009822	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309009823	motif II; other site
257309009824	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309009825	HMMPfam hit to PF01842, ACT domain
257309009826	HMMPfam hit to PF01842, ACT domain
257309009827	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
257309009828	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
257309009829	D-pathway; other site
257309009830	Putative ubiquinol binding site [chemical binding]; other site
257309009831	Low-spin heme (heme b) binding site [chemical binding]; other site
257309009832	Putative water exit pathway; other site
257309009833	Binuclear center (heme o3/CuB) [ion binding]; other site
257309009834	K-pathway; other site
257309009835	Putative proton exit pathway; other site
257309009836	12 probable transmembrane helices predicted for DIP1864 by TMHMM2.0
257309009837	HMMPfam hit to PF00115, Cytochrome C and Quinol oxidase polypeptide I
257309009838	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009839	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009840	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009841	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009842	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009843	ScanRegExp hit to PS00077, Heme-copper oxidase catalytic subunit, copper B binding region signature.
257309009844	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009845	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009846	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009847	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009848	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009849	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009850	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009851	FPrintScan hit to PR01165, Cytochrome c oxidase subunit I signature
257309009852	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
257309009853	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
257309009854	dimer interface [polypeptide binding]; other site
257309009855	putative radical transfer pathway; other site
257309009856	diiron center [ion binding]; other site
257309009857	tyrosyl radical; other site
257309009858	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain
257309009859	ScanRegExp hit to PS00368, Ribonucleotide reductase small subunit signature.
257309009860	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
257309009861	Ferritin-like domain; Region: Ferritin; pfam00210
257309009862	ferroxidase diiron center [ion binding]; other site
257309009863	BlastProDom hit to PD000971, PD000971
257309009864	FPrintScan hit to PR00601, Bacterioferritin signature
257309009865	HMMPfam hit to PF00210, Ferritin
257309009866	FPrintScan hit to PR00601, Bacterioferritin signature
257309009867	FPrintScan hit to PR00601, Bacterioferritin signature
257309009868	FPrintScan hit to PR00601, Bacterioferritin signature
257309009869	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
257309009870	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
257309009871	Class I ribonucleotide reductase; Region: RNR_I; cd01679
257309009872	active site
257309009873	dimer interface [polypeptide binding]; other site
257309009874	catalytic residues [active]
257309009875	effector binding site; other site
257309009876	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
257309009877	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel domain
257309009878	FPrintScan hit to PR01183, Ribonucleotide reductase large chain signature
257309009879	ScanRegExp hit to PS00089, Ribonucleotide reductase large subunit signature.
257309009880	FPrintScan hit to PR01183, Ribonucleotide reductase large chain signature
257309009881	FPrintScan hit to PR01183, Ribonucleotide reductase large chain signature
257309009882	FPrintScan hit to PR01183, Ribonucleotide reductase large chain signature
257309009883	FPrintScan hit to PR01183, Ribonucleotide reductase large chain signature
257309009884	FPrintScan hit to PR01183, Ribonucleotide reductase large chain signature
257309009885	HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha domain
257309009886	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
257309009887	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
257309009888	catalytic residues [active]
257309009889	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
257309009890	active site lid residues [active]
257309009891	substrate binding pocket [chemical binding]; other site
257309009892	catalytic residues [active]
257309009893	substrate-Mg2+ binding site; other site
257309009894	aspartate-rich region 1; other site
257309009895	aspartate-rich region 2; other site
257309009896	HMMPfam hit to PF00494, Squalene/phytoene synthase
257309009897	ScanRegExp hit to PS01045, Squalene and phytoene synthases signature 2.
257309009898	phytoene desaturase; Region: crtI_fam; TIGR02734
257309009899	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
257309009900	FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309009901	HMMPfam hit to PF02032, Phytoene dehydrogenase related enzyme
257309009902	1 probable transmembrane helix predicted for DIP1871 by TMHMM2.0
257309009903	FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309009904	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
257309009905	HMMPfam hit to PF00444, Ribosomal protein L36
257309009906	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
257309009907	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
257309009908	homodimer interface [polypeptide binding]; other site
257309009909	NAD binding pocket [chemical binding]; other site
257309009910	ATP binding pocket [chemical binding]; other site
257309009911	Mg binding site [ion binding]; other site
257309009912	active-site loop [active]
257309009913	HMMPfam hit to PF02540, NAD synthase
257309009914	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
257309009915	Uncharacterized conserved protein (DUF2249); Region: DUF2249; pfam10006
257309009916	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
257309009917	nitrite reductase, copper-containing; Region: Cu_nitrite_red; TIGR02376
257309009918	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
257309009919	HMMPfam hit to PF00394, Multicopper oxidase
257309009920	HMMPfam hit to PF00394, Multicopper oxidase
257309009921	FPrintScan hit to PR00695, Copper containing nitrite reductase signature
257309009922	FPrintScan hit to PR00695, Copper containing nitrite reductase signature
257309009923	FPrintScan hit to PR00695, Copper containing nitrite reductase signature
257309009924	1 probable transmembrane helix predicted for DIP1876 by TMHMM2.0
257309009925	12 probable transmembrane helices predicted for DIP1877 by TMHMM2.0
257309009926	12 probable transmembrane helices predicted for DIP1878 by TMHMM2.0
257309009927	Predicted transcriptional regulator [Transcription]; Region: COG2345
257309009928	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
257309009929	Predicted helix-turn-helix motif with score 1405 (+3.97 SD) at aa 34-55, sequence ISLTDISRMVGGHPNASRQHIK
257309009930	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
257309009931	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
257309009932	catalytic residues [active]
257309009933	Methylamine utilisation protein MauE; Region: MauE; pfam07291
257309009934	4 probable transmembrane helices predicted for DIP1881 by TMHMM2.0
257309009935	phosphoglucomutase; Validated; Region: PRK07564
257309009936	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
257309009937	active site
257309009938	substrate binding site [chemical binding]; other site
257309009939	metal binding site [ion binding]; metal-binding site
257309009940	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-terminal domain
257309009941	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
257309009942	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
257309009943	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
257309009944	ScanRegExp hit to PS00710, Phosphoglucomutase and phosphomannomutase phosphoserine signature.
257309009945	camphor resistance protein CrcB; Provisional; Region: ccrB; PRK00134
257309009946	HMMPfam hit to PF02537, CrcB-like protein
257309009947	3 probable transmembrane helices predicted for DIP1883 by TMHMM2.0
257309009948	CrcB-like protein; Region: CRCB; pfam02537
257309009949	HMMPfam hit to PF02537, CrcB-like protein
257309009950	3 probable transmembrane helices predicted for DIP1884 by TMHMM2.0
257309009951	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
257309009952	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
257309009953	FtsX-like permease family; Region: FtsX; pfam02687
257309009954	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
257309009955	FtsX-like permease family; Region: FtsX; pfam02687
257309009956	HMMPfam hit to PF02687, Predicted permease
257309009957	10 probable transmembrane helices predicted for DIP1885 by TMHMM2.0
257309009958	HMMPfam hit to PF02687, Predicted permease
257309009959	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309009960	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
257309009961	Walker A/P-loop; other site
257309009962	ATP binding site [chemical binding]; other site
257309009963	Q-loop/lid; other site
257309009964	ABC transporter signature motif; other site
257309009965	Walker B; other site
257309009966	D-loop; other site
257309009967	H-loop/switch region; other site
257309009968	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309009969	HMMPfam hit to PF00005, ABC transporter
257309009970	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309009971	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309009972	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309009973	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
257309009974	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
257309009975	hinge; other site
257309009976	active site
257309009977	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
257309009978	BlastProDom hit to PD001867, PD001867
257309009979	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
257309009980	HMMPfam hit to PF01923, Protein of unknown function DUF80
257309009981	BlastProDom hit to PD007457, PD007457
257309009982	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
257309009983	GAF domain; Region: GAF_2; pfam13185
257309009984	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
257309009985	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
257309009986	DNA binding residues [nucleotide binding]
257309009987	dimerization interface [polypeptide binding]; other site
257309009988	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family
257309009989	HMMSmart hit to SM00421, helix_turn_helix, Lux Regulon
257309009990	ProfileScan hit to PS50043, Helix-turn-helix domain, luxR and related types (substantial overlap with lysR type).
257309009991	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309009992	Predicted helix-turn-helix motif with score 1420 (+4.02 SD) at aa 235-256, sequence HTNVEAAEEMGIGAETVKSYLR
257309009993	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309009994	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309009995	HMMSmart hit to SM00065, Domain present in phytochromes and cGMP-specific phosphodiesterases.
257309009996	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
257309009997	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
257309009998	dimer interface [polypeptide binding]; other site
257309009999	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309010000	catalytic residue [active]
257309010001	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme
257309010002	ProfileScan hit to PS50148, Pyridoxalphosphate dependent enzymes.
257309010003	ScanRegExp hit to PS00901, Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
257309010004	serine O-acetyltransferase; Region: cysE; TIGR01172
257309010005	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
257309010006	trimer interface [polypeptide binding]; other site
257309010007	active site
257309010008	substrate binding site [chemical binding]; other site
257309010009	CoA binding site [chemical binding]; other site
257309010010	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010011	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010012	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010013	ScanRegExp hit to PS00101, Hexapeptide-repeat containing-transferases signature.
257309010014	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010015	Predicted acetyltransferase [General function prediction only]; Region: COG2388
257309010016	Glycerol dehydrogenase-like; Region: GlyDH-like2; cd08171
257309010017	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
257309010018	putative active site [active]
257309010019	metal binding site [ion binding]; metal-binding site
257309010020	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
257309010021	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
257309010022	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
257309010023	DNA methylase; Region: N6_N4_Mtase; pfam01555
257309010024	DNA methylase; Region: N6_N4_Mtase; pfam01555
257309010025	HMMPfam hit to PF01555, DNA methylase
257309010026	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309010027	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309010028	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309010029	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309010030	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309010031	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309010032	FPrintScan hit to PR00508, S21 class N4 adenine-specific DNA methyltransferase signature
257309010033	FPrintScan hit to PR00506, D21 class N6 adenine-specific DNA methyltransferase signature
257309010034	ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature.
257309010035	HTH-like domain; Region: HTH_21; pfam13276
257309010036	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
257309010037	HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase
257309010038	9 probable transmembrane helices predicted for DIP1898 by TMHMM2.0
257309010039	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
257309010040	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
257309010041	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
257309010042	HMMPfam hit to PF02322, Cytochrome oxidase subunit II
257309010043	8 probable transmembrane helices predicted for DIP1899 by TMHMM2.0
257309010044	thiol reductant ABC exporter, CydD subunit; Region: CydD; TIGR02857
257309010045	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309010046	Walker A/P-loop; other site
257309010047	ATP binding site [chemical binding]; other site
257309010048	Q-loop/lid; other site
257309010049	ABC transporter signature motif; other site
257309010050	Walker B; other site
257309010051	D-loop; other site
257309010052	H-loop/switch region; other site
257309010053	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309010054	5 probable transmembrane helices predicted for DIP1900 by TMHMM2.0
257309010055	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010056	HMMPfam hit to PF00005, ABC transporter
257309010057	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309010058	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010059	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010060	thiol reductant ABC exporter, CydC subunit; Region: CydC; TIGR02868
257309010061	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309010062	Walker A/P-loop; other site
257309010063	ATP binding site [chemical binding]; other site
257309010064	Q-loop/lid; other site
257309010065	ABC transporter signature motif; other site
257309010066	Walker B; other site
257309010067	D-loop; other site
257309010068	H-loop/switch region; other site
257309010069	4 probable transmembrane helices predicted for DIP1901 by TMHMM2.0
257309010070	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010071	HMMPfam hit to PF00005, ABC transporter
257309010072	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309010073	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010074	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010075	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
257309010076	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
257309010077	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
257309010078	HMMPfam hit to PF02550, Acetyl-CoA hydrolase/transferase
257309010079	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
257309010080	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
257309010081	FMN binding site [chemical binding]; other site
257309010082	active site
257309010083	catalytic residues [active]
257309010084	substrate binding site [chemical binding]; other site
257309010085	HMMPfam hit to PF01207, Uncharacterized protein family UPF0034
257309010086	ScanRegExp hit to PS01136, Uncharacterized protein family UPF0034 signature.
257309010087	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309010088	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
257309010089	PhoU domain; Region: PhoU; pfam01895
257309010090	Pseudogene. Similar to Escherichia coli phosphate transport ATP-binding protein PstB SW:PSTB_ECOLI (P07655) (257 aa) fasta scores: E(): 1.5e-46, 57.64% id in 255 aa, and to Mycobacterium tuberculosis phosphate transport system ATP-binding protein Rv0820 TR:O53832 (EMBL:AL022004) (258 aa) fasta scores: E(): 2.1e-61, 70.58% id in 255 aa. Contains an in-frame stop codon; phosphate transport ATP-binding protein (pseudogene)
257309010091	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010092	HMMPfam hit to PF00005, ABC transporter
257309010093	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010094	ScanRegExp hit to PS00211, ABC transporters family signature.
257309010095	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309010096	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010097	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
257309010098	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309010099	dimer interface [polypeptide binding]; other site
257309010100	conserved gate region; other site
257309010101	putative PBP binding loops; other site
257309010102	ABC-ATPase subunit interface; other site
257309010103	6 probable transmembrane helices predicted for DIP1908 by TMHMM2.0
257309010104	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309010105	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309010106	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
257309010107	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309010108	dimer interface [polypeptide binding]; other site
257309010109	conserved gate region; other site
257309010110	putative PBP binding loops; other site
257309010111	ABC-ATPase subunit interface; other site
257309010112	7 probable transmembrane helices predicted for DIP1909 by TMHMM2.0
257309010113	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309010114	ScanRegExp hit to PS00402, Binding-protein-dependent transport systems inner membrane comp. sign.
257309010115	PBP superfamily domain; Region: PBP_like_2; cl17296
257309010116	HMMPfam hit to PF01449, Phosphate-binding protein
257309010117	mycothiol synthase; Region: mycothiol_MshD; TIGR03448
257309010118	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309010119	Coenzyme A binding pocket [chemical binding]; other site
257309010120	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
257309010121	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309010122	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
257309010123	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
257309010124	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
257309010125	BlastProDom hit to PD005043, PD005043
257309010126	HMMSmart hit to SM00046, Diacylglycerol kinase catalytic domain (presumed)
257309010127	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (presumed)
257309010128	nitrobindin heme-binding domain; Region: nitrobindin; cd07828
257309010129	heme-binding site [chemical binding]; other site
257309010130	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
257309010131	substrate binding site [chemical binding]; other site
257309010132	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
257309010133	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
257309010134	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309010135	catalytic residue [active]
257309010136	HMMPfam hit to PF01063, Aminotransferase class IV
257309010137	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
257309010138	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
257309010139	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
257309010140	Protein of unknown function (DUF3073); Region: DUF3073; pfam11273
257309010141	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
257309010142	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
257309010143	dimerization interface [polypeptide binding]; other site
257309010144	putative ATP binding site [chemical binding]; other site
257309010145	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal domain
257309010146	HMMPfam hit to PF00586, AIR synthase related protein, N-terminal domain
257309010147	amidophosphoribosyltransferase; Provisional; Region: PRK07847
257309010148	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
257309010149	active site
257309010150	tetramer interface [polypeptide binding]; other site
257309010151	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309010152	active site
257309010153	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309010154	ScanRegExp hit to PS00103, Purine/pyrimidine phosphoribosyl transferases signature.
257309010155	HMMPfam hit to PF00310, Glutamine amidotransferases class-II
257309010156	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
257309010157	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
257309010158	7 probable transmembrane helices predicted for DIP1922 by TMHMM2.0
257309010159	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
257309010160	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
257309010161	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
257309010162	dimer interface [polypeptide binding]; other site
257309010163	putative radical transfer pathway; other site
257309010164	diiron center [ion binding]; other site
257309010165	tyrosyl radical; other site
257309010166	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain
257309010167	1 probable transmembrane helix predicted for DIP1924 by TMHMM2.0
257309010168	Pseudogene. Similar to Corynebacterium glutamicum transposase TR:AAL31543 (EMBL:AF435074) (436 aa) fasta scores: E(): 2e-10, 59.64% id in 57 aa; transposase pseudogene
257309010169	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
257309010170	catalytic residues [active]
257309010171	dimer interface [polypeptide binding]; other site
257309010172	FPrintScan hit to PR01011, Glutathione peroxidase signature
257309010173	HMMPfam hit to PF00255, Glutathione peroxidase
257309010174	FPrintScan hit to PR01011, Glutathione peroxidase signature
257309010175	FPrintScan hit to PR01011, Glutathione peroxidase signature
257309010176	ScanRegExp hit to PS00460, Glutathione peroxidases active site.
257309010177	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
257309010178	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
257309010179	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309010180	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309010181	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309010182	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309010183	HMMPfam hit to PF00326, Prolyl oligopeptidase
257309010184	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309010185	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010186	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309010187	FPrintScan hit to PR00862, Prolyl oligopeptidase serine protease (S9A) signature
257309010188	HMMPfam hit to PF02897, Prolyl oligopeptidase, N-terminal beta-propeller domain
257309010189	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010190	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
257309010191	ATP binding site [chemical binding]; other site
257309010192	active site
257309010193	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
257309010194	substrate binding site [chemical binding]; other site
257309010195	HMMPfam hit to PF01259, SAICAR synthetase
257309010196	BlastProDom hit to PD003043, PD003043
257309010197	ScanRegExp hit to PS01058, SAICAR synthetase signature 2.
257309010198	adenylosuccinate lyase; Region: purB; TIGR00928
257309010199	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
257309010200	tetramer interface [polypeptide binding]; other site
257309010201	HMMPfam hit to PF00206, Lyase
257309010202	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309010203	ScanRegExp hit to PS00163, Fumarate lyases signature.
257309010204	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309010205	HMMPfam hit to PF00206, Lyase
257309010206	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309010207	FPrintScan hit to PR00149, Fumarate lyase superfamily signature
257309010208	aspartate aminotransferase; Provisional; Region: PRK05764
257309010209	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309010210	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309010211	homodimer interface [polypeptide binding]; other site
257309010212	catalytic residue [active]
257309010213	HMMPfam hit to PF00155, Aminotransferase class I and II
257309010214	ScanRegExp hit to PS00105, Aminotransferases class-I pyridoxal-phosphate attachment site.
257309010215	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309010216	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309010217	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309010218	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309010219	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
257309010220	TrkA-N domain; Region: TrkA_N; pfam02254
257309010221	TrkA-C domain; Region: TrkA_C; pfam02080
257309010222	HMMPfam hit to PF02254, KTN NAD-binding domain
257309010223	ProfileScan hit to PS50205, NAD binding site.
257309010224	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
257309010225	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
257309010226	HMMPfam hit to PF02386, Sodium transport protein
257309010227	9 probable transmembrane helices predicted for DIP1931 by TMHMM2.0
257309010228	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
257309010229	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
257309010230	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
257309010231	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
257309010232	HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, C domain
257309010233	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
257309010234	ScanRegExp hit to PS00184, Phosphoribosylglycinamide synthetase signature.
257309010235	HMMPfam hit to PF02842, Phosphoribosylglycinamide synthetase, B domain
257309010236	HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, N domain
257309010237	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
257309010238	nucleotide binding site/active site [active]
257309010239	HIT family signature motif; other site
257309010240	catalytic residue [active]
257309010241	HMMPfam hit to PF01230, HIT family
257309010242	FPrintScan hit to PR00332, Histidine triad family signature
257309010243	FPrintScan hit to PR00332, Histidine triad family signature
257309010244	ScanRegExp hit to PS00892, HIT family signature.
257309010245	FPrintScan hit to PR00332, Histidine triad family signature
257309010246	PGAP1-like protein; Region: PGAP1; pfam07819
257309010247	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
257309010248	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309010249	ScanRegExp hit to PS00120, Lipases, serine active site.
257309010250	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
257309010251	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
257309010252	dimerization interface [polypeptide binding]; other site
257309010253	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
257309010254	dimer interface [polypeptide binding]; other site
257309010255	phosphorylation site [posttranslational modification]
257309010256	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309010257	ATP binding site [chemical binding]; other site
257309010258	Mg2+ binding site [ion binding]; other site
257309010259	G-X-G motif; other site
257309010260	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309010261	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309010262	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309010263	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309010264	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309010265	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309010266	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain; HMMSmart hit to SM00388, His Kinase A (phosphoacceptor) domain
257309010267	HMMSmart hit to SM00304, HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
257309010268	HMMPfam hit to PF00672, HAMP domain
257309010269	2 probable transmembrane helices predicted for DIP1935 by TMHMM2.0
257309010270	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
257309010271	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309010272	active site
257309010273	phosphorylation site [posttranslational modification]
257309010274	intermolecular recognition site; other site
257309010275	dimerization interface [polypeptide binding]; other site
257309010276	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
257309010277	DNA binding site [nucleotide binding]
257309010278	HMMPfam hit to PF00486, Transcriptional regulatory protein, C terminal
257309010279	HMMPfam hit to PF00072, Response regulator receiver domain
257309010280	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309010281	ScanRegExp hit to PS00217, Sugar transport proteins signature 2.
257309010282	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309010283	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; cl00789
257309010284	1 probable transmembrane helix predicted for DIP1938 by TMHMM2.0
257309010285	PspC domain; Region: PspC; pfam04024
257309010286	1 probable transmembrane helix predicted for DIP1939 by TMHMM2.0
257309010287	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309010288	Major Facilitator Superfamily; Region: MFS_1; pfam07690
257309010289	putative substrate translocation pore; other site
257309010290	14 probable transmembrane helices predicted for DIP1941 by TMHMM2.0
257309010291	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309010292	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309010293	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309010294	xanthine permease; Region: pbuX; TIGR03173
257309010295	OHCU decarboxylase; Region: OHCU_decarbox; cl01251
257309010296	HMMPfam hit to PF00860, Xanthine/uracil permeases family
257309010297	11 probable transmembrane helices predicted for DIP1943 by TMHMM2.0
257309010298	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
257309010299	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
257309010300	Integrase core domain; Region: rve; pfam00665
257309010301	HMMPfam hit to PF00665, Integrase core domain
257309010302	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
257309010303	HMMPfam hit to PF00589, Phage integrase
257309010304	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like domain
257309010305	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
257309010306	dihydropteroate synthase; Region: DHPS; TIGR01496
257309010307	substrate binding pocket [chemical binding]; other site
257309010308	dimer interface [polypeptide binding]; other site
257309010309	inhibitor binding site; inhibition site
257309010310	ScanRegExp hit to PS00792, Dihydropteroate synthase signature 1.
257309010311	HMMPfam hit to PF00809, Dihydropteroate synthase
257309010312	ScanRegExp hit to PS00793, Dihydropteroate synthase signature 2.
257309010313	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
257309010314	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309010315	Coenzyme A binding pocket [chemical binding]; other site
257309010316	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309010317	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
257309010318	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
257309010319	Integrase core domain; Region: rve; pfam00665
257309010320	HMMPfam hit to PF00665, Integrase core domain
257309010321	pyruvate dehydrogenase; Provisional; Region: PRK06546
257309010322	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
257309010323	PYR/PP interface [polypeptide binding]; other site
257309010324	dimer interface [polypeptide binding]; other site
257309010325	tetramer interface [polypeptide binding]; other site
257309010326	TPP binding site [chemical binding]; other site
257309010327	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
257309010328	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
257309010329	TPP-binding site [chemical binding]; other site
257309010330	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
257309010331	ScanRegExp hit to PS00187, Thiamine pyrophosphate enzymes signature.
257309010332	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central domain
257309010333	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
257309010334	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
257309010335	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
257309010336	9 probable transmembrane helices predicted for DIP1953 by TMHMM2.0
257309010337	putative transposase OrfB; Reviewed; Region: PHA02517
257309010338	HTH-like domain; Region: HTH_21; pfam13276
257309010339	Integrase core domain; Region: rve; pfam00665
257309010340	Integrase core domain; Region: rve_2; pfam13333
257309010341	HMMPfam hit to PF00665, Integrase core domain
257309010342	Winged helix-turn helix; Region: HTH_29; pfam13551
257309010343	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309010344	Homeodomain-like domain; Region: HTH_32; pfam13565
257309010345	Predicted helix-turn-helix motif with score 1504 (+4.31 SD) at aa 14-35, sequence PTPSQAADKAGVSKATLLRHVN
257309010346	Domain of unknown function (DUF955); Region: DUF955; pfam06114
257309010347	ScanRegExp hit to PS00142, Neutral zinc metallopeptidases, zinc-binding region signature.
257309010348	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
257309010349	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
257309010350	HTH-like domain; Region: HTH_21; pfam13276
257309010351	Integrase core domain; Region: rve; pfam00665
257309010352	Integrase core domain; Region: rve_2; pfam13333
257309010353	HMMPfam hit to PF00665, Integrase core domain
257309010354	Uncharacterized conserved protein [Function unknown]; Region: COG2966
257309010355	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
257309010356	Uncharacterized conserved protein [Function unknown]; Region: COG3610
257309010357	8 probable transmembrane helices predicted for DIP1964 by TMHMM2.0
257309010358	ProfileScan hit to PS50323, Arginine-rich region.
257309010359	ProfileScan hit to PS50318, Lysine-rich region.
257309010360	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
257309010361	Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism]; Region: OtsA; COG0380
257309010362	active site
257309010363	homotetramer interface [polypeptide binding]; other site
257309010364	HMMPfam hit to PF00982, Glycosyltransferase 20
257309010365	META domain; Region: META; cl01245
257309010366	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
257309010367	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
257309010368	HMMPfam hit to PF02358, Trehalose-phosphatase
257309010369	Transcriptional regulators [Transcription]; Region: PurR; COG1609
257309010370	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
257309010371	DNA binding site [nucleotide binding]
257309010372	domain linker motif; other site
257309010373	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_3; cd06279
257309010374	putative dimerization interface [polypeptide binding]; other site
257309010375	putative ligand binding site [chemical binding]; other site
257309010376	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar binding domain of the LacI family.
257309010377	HMMSmart hit to SM00354, helix_turn _helix lactose operon repressor, DNA-binding
257309010378	Predicted helix-turn-helix motif with score 1881 (+5.59 SD) at aa 13-34, sequence PSLAALAAELGVSRTTVSNAYN
257309010379	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
257309010380	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
257309010381	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
257309010382	BlastProDom hit to PD001243, PD001243
257309010383	HMMPfam hit to PF00588, SpoU rRNA Methylase
257309010384	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
257309010385	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309010386	active site
257309010387	HIGH motif; other site
257309010388	nucleotide binding site [chemical binding]; other site
257309010389	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
257309010390	KMSKS motif; other site
257309010391	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
257309010392	HMMPfam hit to PF01406, tRNA synthetases class I (C)
257309010393	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309010394	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309010395	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309010396	FPrintScan hit to PR00983, Cysteinyl-tRNA synthetase signature
257309010397	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
257309010398	homotrimer interaction site [polypeptide binding]; other site
257309010399	zinc binding site [ion binding]; other site
257309010400	CDP-binding sites; other site
257309010401	HMMPfam hit to PF02542, YgbB family
257309010402	ScanRegExp hit to PS01350, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature.
257309010403	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
257309010404	substrate binding site; other site
257309010405	dimer interface; other site
257309010406	HMMPfam hit to PF01128, Uncharacterized protein family UPF0007
257309010407	ScanRegExp hit to PS01295, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature.
257309010408	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
257309010409	HMMPfam hit to PF02559, CarD-like transcriptional regulator
257309010410	1 probable transmembrane helix predicted for DIP1976 by TMHMM2.0
257309010411	DNA repair protein RadA; Provisional; Region: PRK11823
257309010412	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
257309010413	Walker A motif; other site
257309010414	ATP binding site [chemical binding]; other site
257309010415	Walker B motif; other site
257309010416	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
257309010417	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010418	FPrintScan hit to PR00830, Endopeptidase La (Lon) serine protease (S16) signature
257309010419	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010420	FPrintScan hit to PR00830, Endopeptidase La (Lon) serine protease (S16) signature
257309010421	FPrintScan hit to PR00830, Endopeptidase La (Lon) serine protease (S16) signature
257309010422	FPrintScan hit to PR00830, Endopeptidase La (Lon) serine protease (S16) signature
257309010423	ProfileScan hit to PS50324, Serine-rich region.
257309010424	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
257309010425	active site clefts [active]
257309010426	zinc binding site [ion binding]; other site
257309010427	dimer interface [polypeptide binding]; other site
257309010428	HMMPfam hit to PF00484, Carbonic anhydrase
257309010429	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
257309010430	endonuclease III; Region: ENDO3c; smart00478
257309010431	minor groove reading motif; other site
257309010432	helix-hairpin-helix signature motif; other site
257309010433	substrate binding pocket [chemical binding]; other site
257309010434	active site
257309010435	HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair protein
257309010436	HMMSmart hit to SM00478, endonuclease III
257309010437	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
257309010438	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
257309010439	10 probable transmembrane helices predicted for DIP1981 by TMHMM2.0
257309010440	ScanRegExp hit to PS00339, Aminoacyl-transfer RNA synthetases class-II signature 2.
257309010441	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
257309010442	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
257309010443	Clp amino terminal domain; Region: Clp_N; pfam02861
257309010444	Clp amino terminal domain; Region: Clp_N; pfam02861
257309010445	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309010446	Walker A motif; other site
257309010447	ATP binding site [chemical binding]; other site
257309010448	Walker B motif; other site
257309010449	arginine finger; other site
257309010450	UvrB/uvrC motif; Region: UVR; pfam02151
257309010451	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309010452	Walker A motif; other site
257309010453	ATP binding site [chemical binding]; other site
257309010454	Walker B motif; other site
257309010455	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
257309010456	Predicted helix-turn-helix motif with score 986 (+2.55 SD) at aa 743-764, sequence LTQEQIVEMVDLLIGRVSKALA
257309010457	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010458	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010459	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010460	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010461	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010462	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010463	HMMPfam hit to PF02151, UvrB/uvrC motif; ProfileScan hit to PS50151, UvrB/uvrC motif.
257309010464	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309010465	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010466	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010467	HMMPfam hit to PF02861, Clp amino terminal domain
257309010468	HMMPfam hit to PF02861, Clp amino terminal domain
257309010469	putative septicolysin, cholesterol-dependent cytolysin family and related proteins; Region: septicolysin_like; cd12208
257309010470	oligomer interface [polypeptide binding]; other site
257309010471	6 probable transmembrane helices predicted for DIP1985 by TMHMM2.0
257309010472	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
257309010473	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
257309010474	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309010475	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature
257309010476	HMMPfam hit to PF00561, alpha/beta hydrolase fold
257309010477	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature
257309010478	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature
257309010479	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
257309010480	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
257309010481	dimer interface [polypeptide binding]; other site
257309010482	putative anticodon binding site; other site
257309010483	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
257309010484	motif 1; other site
257309010485	dimer interface [polypeptide binding]; other site
257309010486	active site
257309010487	motif 2; other site
257309010488	motif 3; other site
257309010489	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N)
257309010490	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309010491	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature; ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309010492	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309010493	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309010494	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309010495	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain
257309010496	Transposase; Region: DEDD_Tnp_IS110; pfam01548
257309010497	YcaO-like family; Region: YcaO; pfam02624
257309010498	6 probable transmembrane helices predicted for DIP1989 by TMHMM2.0
257309010499	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309010500	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
257309010501	Walker A/P-loop; other site
257309010502	ATP binding site [chemical binding]; other site
257309010503	Q-loop/lid; other site
257309010504	ABC transporter signature motif; other site
257309010505	Walker B; other site
257309010506	D-loop; other site
257309010507	H-loop/switch region; other site
257309010508	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010509	HMMPfam hit to PF00005, ABC transporter
257309010510	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010511	ScanRegExp hit to PS00211, ABC transporters family signature.
257309010512	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309010513	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010514	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
257309010515	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_2; cd03402
257309010516	2 probable transmembrane helices predicted for DIP1991 by TMHMM2.0
257309010517	HMMSmart hit to SM00244, prohibitin homologues
257309010518	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
257309010519	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
257309010520	8 probable transmembrane helices predicted for DIP1992 by TMHMM2.0
257309010521	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010522	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family
257309010523	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010524	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010525	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010526	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010527	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010528	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010529	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309010530	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309010531	active site
257309010532	KMSKS motif; other site
257309010533	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
257309010534	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
257309010535	2 probable transmembrane helices predicted for DIP1995 by TMHMM2.0
257309010536	Protein of unknown function (DUF3180); Region: DUF3180; pfam11377
257309010537	2 probable transmembrane helices predicted for DIP1996 by TMHMM2.0
257309010538	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
257309010539	catalytic center binding site [active]
257309010540	ATP binding site [chemical binding]; other site
257309010541	HMMPfam hit to PF01288, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
257309010542	ScanRegExp hit to PS00794, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature.
257309010543	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
257309010544	homooctamer interface [polypeptide binding]; other site
257309010545	active site
257309010546	HMMPfam hit to PF02152, Dihydroneopterin aldolase
257309010547	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
257309010548	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
257309010549	substrate binding pocket [chemical binding]; other site
257309010550	dimer interface [polypeptide binding]; other site
257309010551	inhibitor binding site; inhibition site
257309010552	HMMPfam hit to PF00809, Dihydropteroate synthase
257309010553	ScanRegExp hit to PS00793, Dihydropteroate synthase signature 2.
257309010554	ScanRegExp hit to PS00792, Dihydropteroate synthase signature 1.
257309010555	Protein of unknown function, DUF393; Region: DUF393; pfam04134
257309010556	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
257309010557	homodecamer interface [polypeptide binding]; other site
257309010558	GTP cyclohydrolase I; Provisional; Region: PLN03044
257309010559	active site
257309010560	putative catalytic site residues [active]
257309010561	zinc binding site [ion binding]; other site
257309010562	GTP-CH-I/GFRP interaction surface; other site
257309010563	HMMPfam hit to PF01227, GTP cyclohydrolase I
257309010564	BlastProDom hit to PD003330, PD003330
257309010565	ScanRegExp hit to PS00860, GTP cyclohydrolase I signature 2.
257309010566	ScanRegExp hit to PS00859, GTP cyclohydrolase I signature 1.
257309010567	FtsH Extracellular; Region: FtsH_ext; pfam06480
257309010568	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
257309010569	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309010570	Walker A motif; other site
257309010571	ATP binding site [chemical binding]; other site
257309010572	Walker B motif; other site
257309010573	arginine finger; other site
257309010574	Peptidase family M41; Region: Peptidase_M41; pfam01434
257309010575	HMMPfam hit to PF01434, Peptidase M41
257309010576	FPrintScan hit to PR00830, Endopeptidase La (Lon) serine protease (S16) signature
257309010577	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309010578	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010579	ScanRegExp hit to PS00674, AAA-protein family signature.
257309010580	FPrintScan hit to PR00830, Endopeptidase La (Lon) serine protease (S16) signature
257309010581	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010582	2 probable transmembrane helices predicted for DIP2002 by TMHMM2.0
257309010583	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309010584	active site
257309010585	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309010586	ScanRegExp hit to PS00103, Purine/pyrimidine phosphoribosyl transferases signature.
257309010587	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
257309010588	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
257309010589	Ligand Binding Site [chemical binding]; other site
257309010590	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
257309010591	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
257309010592	HMMPfam hit to PF02113, D-Ala-D-Ala carboxypeptidase 3 (S13) family
257309010593	FPrintScan hit to PR00922, D-Ala-D-Ala carboxypeptidase 3 (S13) family signature
257309010594	FPrintScan hit to PR00922, D-Ala-D-Ala carboxypeptidase 3 (S13) family signature
257309010595	FPrintScan hit to PR00922, D-Ala-D-Ala carboxypeptidase 3 (S13) family signature
257309010596	FPrintScan hit to PR00922, D-Ala-D-Ala carboxypeptidase 3 (S13) family signature
257309010597	HMMPfam hit to PF02113, D-Ala-D-Ala carboxypeptidase 3 (S13) family
257309010598	FPrintScan hit to PR00922, D-Ala-D-Ala carboxypeptidase 3 (S13) family signature
257309010599	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
257309010600	dimer interface [polypeptide binding]; other site
257309010601	substrate binding site [chemical binding]; other site
257309010602	metal binding sites [ion binding]; metal-binding site
257309010603	BlastProDom hit to PD002014, PD002014
257309010604	HMMPfam hit to PF00719, Inorganic pyrophosphatase
257309010605	ScanRegExp hit to PS00387, Inorganic pyrophosphatase signature.
257309010606	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
257309010607	active site residue [active]
257309010608	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309010609	HMMPfam hit to PF00581, Rhodanese-like domain
257309010610	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309010611	Transcriptional regulators [Transcription]; Region: MarR; COG1846
257309010612	MarR family; Region: MarR_2; cl17246
257309010613	HMMSmart hit to SM00347, helix_turn_helix multiple antibiotic resistance protein, DNA-binding
257309010614	HMMPfam hit to PF01047, MarR family
257309010615	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309010616	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309010617	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309010618	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
257309010619	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
257309010620	acyl-activating enzyme (AAE) consensus motif; other site
257309010621	AMP binding site [chemical binding]; other site
257309010622	active site
257309010623	CoA binding site [chemical binding]; other site
257309010624	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
257309010625	non-ribosomal peptide synthetase terminal domain of unknown function; Region: NRPS_term_dom; TIGR02353
257309010626	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
257309010627	putative trimer interface [polypeptide binding]; other site
257309010628	putative CoA binding site [chemical binding]; other site
257309010629	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
257309010630	putative trimer interface [polypeptide binding]; other site
257309010631	putative CoA binding site [chemical binding]; other site
257309010632	HMMPfam hit to PF00501, AMP-binding enzyme
257309010633	FPrintScan hit to PR00154, AMP-binding signature
257309010634	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309010635	FPrintScan hit to PR00154, AMP-binding signature
257309010636	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309010637	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309010638	7 probable transmembrane helices predicted for DIP2009 by TMHMM2.0
257309010639	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010640	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010641	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010642	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010643	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010644	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (four repeats)
257309010645	Anomalous G+C content (49.37%) and dinucleotide signature.  fimbrial related pathogenicity island. Not present in C.glutamicum
257309010646	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
257309010647	metal ion-dependent adhesion site (MIDAS); other site
257309010648	HMMPfam hit to PF00746, Gram positive anchor
257309010649	probable transmembrane helix predicted for DIP2010 by TMHMM2.0
257309010650	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309010651	potential sortase anchor site LPLTG
257309010652	ProfileScan hit to PS50234, VWFA domain profile.
257309010653	1 probable transmembrane helix predicted for DIP2011 by TMHMM2.0
257309010654	potential sortase anchor site LAFTG
257309010655	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
257309010656	active site
257309010657	catalytic site [active]
257309010658	probable transmembrane helix predicted for DIP2012 by TMHMM2.0
257309010659	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
257309010660	HMMPfam hit to PF00746, Gram positive anchor
257309010661	probable transmembrane helix predicted for DIP2013 by TMHMM2.0
257309010662	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309010663	potential sortase anchor site LPLTG
257309010664	1 probable transmembrane helix predicted for DIP2014 by TMHMM2.0
257309010665	Secretory lipase; Region: LIP; pfam03583
257309010666	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309010667	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
257309010668	Domain of unknown function (DUF4185); Region: DUF4185; pfam13810
257309010669	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
257309010670	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
257309010671	ring oligomerisation interface [polypeptide binding]; other site
257309010672	ATP/Mg binding site [chemical binding]; other site
257309010673	stacking interactions; other site
257309010674	hinge regions; other site
257309010675	HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family
257309010676	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309010677	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309010678	ScanRegExp hit to PS00296, Chaperonins cpn60 signature.
257309010679	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309010680	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309010681	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309010682	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309010683	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309010684	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309010685	FPrintScan hit to PR00298, 60kDa chaperonin signature
257309010686	FPrintScan hit to PR00304, Tailless complex polypeptide 1 (chaperone) signature
257309010687	Fic/DOC family; Region: Fic; pfam02661
257309010688	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
257309010689	hypothetical protein; Reviewed; Region: PRK09588
257309010690	HMMPfam hit to PF01139, Uncharacterized protein family UPF0027
257309010691	Pseudogene. Similar to Corynebacterium diphtheriae probable transposase for insertion sequence element SWALL:TRA_CORDI (SWALL:P35879) (343 aa) fasta scores: E(): 3.9e-56, 69.04% id in 294 aa, and to Rhizobium meliloti transposase for insertion sequence element IsrM3 SWALL:TRA3_RHIME (SWALL:P80011) (400 aa) fasta scores: E(): 1.5e-31, 46.57% id in 292 aa. Note: Also similar to DIP0041 to DIP0045 (325 aa) also a pseudogene. Presents multiple frameshifts at residues 55, 71, 161, 152, 170 and 217 and lacks stop codon; transposase for insertion sequence element (pseudogene)
257309010692	HMMPfam hit to PF00872, Transposase, Mutator family
257309010693	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
257309010694	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
257309010695	FMN binding site [chemical binding]; other site
257309010696	active site
257309010697	substrate binding site [chemical binding]; other site
257309010698	catalytic residue [active]
257309010699	HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidase
257309010700	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
257309010701	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
257309010702	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
257309010703	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309010704	Walker A/P-loop; other site
257309010705	ATP binding site [chemical binding]; other site
257309010706	Q-loop/lid; other site
257309010707	ABC transporter signature motif; other site
257309010708	Walker B; other site
257309010709	D-loop; other site
257309010710	H-loop/switch region; other site
257309010711	HMMPfam hit to PF00005, ABC transporter
257309010712	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010713	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010714	ScanRegExp hit to PS00211, ABC transporters family signature.
257309010715	HMMPfam hit to PF00005, ABC transporter
257309010716	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010717	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010718	ScanRegExp hit to PS00211, ABC transporters family signature.
257309010719	intracellular protease, PfpI family; Region: PfpI; TIGR01382
257309010720	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
257309010721	proposed catalytic triad [active]
257309010722	conserved cys residue [active]
257309010723	HMMPfam hit to PF01965, ThiJ/PfpI family
257309010724	Pseudogene. Similar partially to Corynebacterium diphtheriae probable transposase for insertion sequence element SWALL:TRA_CORDI (SWALL:P35879) (343 aa) fasta scores: E(): 2.7e-38, 72.26% id in 137 aa, and to Yersinia pestis transposase SWALL:O68779 (EMBL:AF053947) (402 aa) fasta scores: E(): 9.3e-21, 35.29% id in 170 aa. Note: Also similar to DIP0045-DIP0041 and to DIP202-DIP2029, also pseudogenes. Presents frameshifts at residues 92 and 131; transposase
257309010725	HMMPfam hit to PF00872, Transposase, Mutator family
257309010726	2 probable transmembrane helices predicted for DIP2036 by TMHMM2.0
257309010727	hypothetical protein; Provisional; Region: PRK07907
257309010728	M20 Dipeptidases; Region: M20_Dipept_like; cd03893
257309010729	active site
257309010730	metal binding site [ion binding]; metal-binding site
257309010731	dimer interface [polypeptide binding]; other site
257309010732	HMMPfam hit to PF01546, Peptidase M20/M25/M40
257309010733	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
257309010734	11 probable transmembrane helices predicted for DIP2040 by TMHMM2.0
257309010735	carboxylate-amine ligase; Provisional; Region: PRK13517
257309010736	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
257309010737	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
257309010738	1 probable transmembrane helix predicted for DIP2043 by TMHMM2.0
257309010739	Protein of unknown function (DUF3263); Region: DUF3263; pfam11662
257309010740	Predicted helix-turn-helix motif with score 1050 (+2.76 SD) at aa 20-41, sequence GAKEEAIRELGLTPVRYYQMLN
257309010741	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
257309010742	active site
257309010743	catalytic residues [active]
257309010744	metal binding site [ion binding]; metal-binding site
257309010745	HMMPfam hit to PF01327, Polypeptide deformylase
257309010746	BlastProDom hit to PD003844, PD003844
257309010747	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
257309010748	Coenzyme A binding pocket [chemical binding]; other site
257309010749	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family
257309010750	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
257309010751	putative catalytic site [active]
257309010752	putative metal binding site [ion binding]; other site
257309010753	putative phosphate binding site [ion binding]; other site
257309010754	HMMPfam hit to PF01260, AP endonuclease 1
257309010755	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
257309010756	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
257309010757	putative active site [active]
257309010758	catalytic site [active]
257309010759	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
257309010760	putative active site [active]
257309010761	catalytic site [active]
257309010762	2 probable transmembrane helices predicted for DIP2048 by TMHMM2.0
257309010763	HMMPfam hit to PF00614, Phospholipase D. Active site motif; HMMSmart hit to SM00155, Phospholipase D. Active site motifs.; ProfileScan hit to PS50035, Phospholipase D/Transphosphatidylase (also polyphosphate kinases, secreted nucleases)
257309010764	HMMPfam hit to PF00614, Phospholipase D. Active site motif; HMMSmart hit to SM00155, Phospholipase D. Active site motifs.; ProfileScan hit to PS50035, Phospholipase D/Transphosphatidylase (also polyphosphate kinases, secreted nucleases)
257309010765	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
257309010766	6 probable transmembrane helices predicted for DIP2049 by TMHMM2.0
257309010767	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309010768	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309010769	Walker A/P-loop; other site
257309010770	ATP binding site [chemical binding]; other site
257309010771	Q-loop/lid; other site
257309010772	ABC transporter signature motif; other site
257309010773	Walker B; other site
257309010774	D-loop; other site
257309010775	H-loop/switch region; other site
257309010776	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010777	HMMPfam hit to PF00005, ABC transporter
257309010778	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010779	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309010780	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010781	4 probable transmembrane helices predicted for DIP2051 by TMHMM2.0
257309010782	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
257309010783	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
257309010784	substrate binding pocket [chemical binding]; other site
257309010785	membrane-bound complex binding site; other site
257309010786	hinge residues; other site
257309010787	HMMSmart hit to SM00062, Bacterial periplasmic substrate-binding proteins
257309010788	HMMPfam hit to PF00497, Bacterial extracellular solute-binding proteins, family 3
257309010789	ProfileScan hit to PS50121, Solute binding protein/glutamate receptor domain.
257309010790	ScanRegExp hit to PS01039, Bacterial extracellular solute-binding proteins, family 3 signature.
257309010791	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
257309010792	Catalytic domain of Protein Kinases; Region: PKc; cd00180
257309010793	active site
257309010794	ATP binding site [chemical binding]; other site
257309010795	substrate binding site [chemical binding]; other site
257309010796	activation loop (A-loop); other site
257309010797	ProfileScan hit to PS50011, Protein kinase domain profile.
257309010798	HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain
257309010799	HMMSmart hit to SM00219, Tyrosine kinase, catalytic domain
257309010800	HMMPfam hit to PF00069, Protein kinase domain
257309010801	ScanRegExp hit to PS00108, Serine/Threonine protein kinases active-site signature.
257309010802	propionate/acetate kinase; Provisional; Region: PRK12379
257309010803	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
257309010804	HMMPfam hit to PF00871, Acetokinase
257309010805	FPrintScan hit to PR00471, Acetate kinase signature
257309010806	FPrintScan hit to PR00471, Acetate kinase signature
257309010807	FPrintScan hit to PR00471, Acetate kinase signature
257309010808	FPrintScan hit to PR00471, Acetate kinase signature
257309010809	FPrintScan hit to PR00471, Acetate kinase signature
257309010810	FPrintScan hit to PR00471, Acetate kinase signature; ScanRegExp hit to PS01075, Acetate and butyrate kinases family signature 1.
257309010811	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
257309010812	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase
257309010813	ferredoxin-NADP+ reductase; Region: PLN02852
257309010814	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
257309010815	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309010816	FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309010817	FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309010818	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309010819	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309010820	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature
257309010821	FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309010822	ATP-grasp domain; Region: ATP-grasp_4; cl17255
257309010823	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
257309010824	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309010825	active site
257309010826	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309010827	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
257309010828	putative active site [active]
257309010829	ScanRegExp hit to PS00639, Eukaryotic thiol (cysteine) proteases histidine active site.
257309010830	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
257309010831	5 probable transmembrane helices predicted for DIP2060 by TMHMM2.0
257309010832	2 probable transmembrane helices predicted for DIP2061 by TMHMM2.0
257309010833	Cna protein B-type domain; Region: Cna_B; pfam05738
257309010834	1 probable transmembrane helix predicted for DIP2062 by TMHMM2.0
257309010835	potential sortase anchor site LAATG
257309010836	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
257309010837	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
257309010838	GDP-binding site [chemical binding]; other site
257309010839	ACT binding site; other site
257309010840	IMP binding site; other site
257309010841	HMMPfam hit to PF00709, Adenylosuccinate synthetase
257309010842	BlastProDom hit to PD001188, PD001188
257309010843	ScanRegExp hit to PS00513, Adenylosuccinate synthetase active site.
257309010844	ScanRegExp hit to PS01266, Adenylosuccinate synthetase GTP-binding site.
257309010845	Anomalous G+C content (52.31%).  fimbrial related pathogenicity island. Not present in C.glutamicum
257309010846	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
257309010847	conserved repeat domain; Region: B_ant_repeat; TIGR01451
257309010848	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
257309010849	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309010850	potential sortase anchor site LPKTG
257309010851	1 probable transmembrane helix predicted for DIP2066 by TMHMM2.0
257309010852	Predicted membrane protein [Function unknown]; Region: COG4129
257309010853	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
257309010854	5 probable transmembrane helices predicted for DIP2068 by TMHMM2.0
257309010855	DtxR-regulated promoter
257309010856	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
257309010857	Predicted membrane protein [Function unknown]; Region: COG4129
257309010858	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
257309010859	4 probable transmembrane helices predicted for DIP2070 by TMHMM2.0
257309010860	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
257309010861	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
257309010862	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
257309010863	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
257309010864	Transposase; Region: HTH_Tnp_1; pfam01527
257309010865	HMMPfam hit to PF01527, Transposase
257309010866	Predicted helix-turn-helix motif with score 1271 (+3.52 SD) at aa 25-46, sequence RPIAYVAKEIGVSAGLLGKWVK
257309010867	1 probable transmembrane helix predicted for DIP2075 by TMHMM2.0
257309010868	1 probable transmembrane helix predicted for DIP2076 by TMHMM2.0
257309010869	putative transporter; Provisional; Region: PRK09821
257309010870	GntP family permease; Region: GntP_permease; pfam02447
257309010871	HMMPfam hit to PF02447, GntP family permease
257309010872	11 probable transmembrane helices predicted for DIP2078 by TMHMM2.0
257309010873	ScanRegExp hit to PS00904, Protein prenyltransferases alpha subunit repeat signature.
257309010874	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
257309010875	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
257309010876	NAD(P) binding site [chemical binding]; other site
257309010877	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
257309010878	Predicted helix-turn-helix motif with score 1101 (+2.94 SD) at aa 58-79, sequence WTEADLAWAFEQNAPAIYVMTN
257309010879	Transcriptional regulators [Transcription]; Region: FadR; COG2186
257309010880	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309010881	DNA-binding site [nucleotide binding]; DNA binding site
257309010882	FCD domain; Region: FCD; pfam07729
257309010883	HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309010884	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family
257309010885	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309010886	Predicted helix-turn-helix motif with score 1055 (+2.78 SD) at aa 29-50, sequence PGEAKLAEFLDVSRPTMREVVR
257309010887	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309010888	Pseudogene. Similar to Rhizobium meliloti  amino acid dehydrogenase transmembrane protein R03117 or SMC03265 SWALL:Q92LE8 (EMBL:AL591793) (429 aa) fasta scores: E(): 3.7e-15, 26.82% id in 410 aa, and to Pseudomonas aeruginosa D-amino acid dehydrogenase, small subunit DadA or PA5304 SWALL:Q9HTQ0 (EMBL:AE004943) (432 aa) fasta scores: E(): 4.5e-14, 27.45% id in 408 aa. Presents a frameshift at residue 60; amino acid dehydrogenase (pseudogene)
257309010889	Transposase; Region: DEDD_Tnp_IS110; pfam01548
257309010890	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
257309010891	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
257309010892	HMMPfam hit to PF01548, Transposase
257309010893	HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family
257309010894	Pseudogene. Highly similar to Corynebacterium striatum GcrY SWALL:Q9FB53 (EMBL:AF024666) (952 aa) fasta scores: E(): 1e-186, 84.13% id in 517 aa, and to Deinococcus radiodurans DNA modification methyltransferase-related protein DR2267 SWALL:Q9RS60 (EMBL:AE002059) (840 aa) fasta scores: E(): 8.1e-16, 26.91% id in 509 aa. Presents a frameshift at residue 260 with two other CDSs inserted at this point;Conserved hypothetical protein (pseudogene)
257309010895	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309010896	Predicted helix-turn-helix motif with score 1095 (+2.92 SD) at aa 23-44, sequence YSYWAAAHHVGVGVYPVRALFR
257309010897	HMMPfam hit to PF01527, Transposase
257309010898	Pseudogene. Similar to Escherichia coli transposase InsK for insertion sequence element IS150 or B3558 SWALL:INSK_ECOLI (SWALL:P19769) (283 aa) fasta scores: E(): 1.4e-45, 44.81% id in 270 aa, and to Ralstonia solanacearum ISRSO11-transposase ORFB protein ITSRSO11B or RSC3089 or RS00541 or RS05742 SWALL:CAD16798 (EMBL:AL646073) (278 aa) fasta scores: E(): 4e-42, 42.91% id in 268 aa. Presents a frameshift at residue 127; transposase (pseudogene)
257309010899	HMMPfam hit to PF00665, Integrase core domain
257309010900	Pseudogene. Similar to part of Corynebacterium jeikeium RepA SWALL:Q93MK3 (EMBL:AF401314) (521 aa) fasta scores: E(): 4.5e-18, 72% id in 75 aa, and to part of Corynebacterium glutamicum replicase RepA SWALL:Q9X539 (EMBL:AF121000) (482 aa) fasta scores: E(): 7.8e-16, 65.33% id in 75 aa. Note: Lacks stop codon; replicase (partial)
257309010901	Predicted helix-turn-helix motif with score 1094 (+2.91 SD) at aa 50-71, sequence PSIPDAMREFGVSSPTVKGALK
257309010902	Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri  transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor  IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180; IS element transposase (pseudogene)
257309010903	Cna protein B-type domain; Region: Cna_B; pfam05738
257309010904	Cna protein B-type domain; Region: Cna_B; pfam05738
257309010905	potential sortase anchor site LAATG
257309010906	1 probable transmembrane helix predicted for DIP2093 by TMHMM2.0
257309010907	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
257309010908	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
257309010909	active site
257309010910	intersubunit interface [polypeptide binding]; other site
257309010911	zinc binding site [ion binding]; other site
257309010912	Na+ binding site [ion binding]; other site
257309010913	HMMPfam hit to PF01116, Fructose-bisphosphate aldolase class-II
257309010914	ScanRegExp hit to PS00806, Fructose-bisphosphate aldolase class-II signature 2.
257309010915	ScanRegExp hit to PS00602, Fructose-bisphosphate aldolase class-II signature 1.
257309010916	Glycosyl hydrolase family 76; Region: Glyco_hydro_76; cl01996
257309010917	ScanRegExp hit to PS00334, Myb DNA-binding domain repeat signature 2.
257309010918	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
257309010919	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
257309010920	BlastProDom hit to PD001243, PD001243
257309010921	HMMPfam hit to PF00588, SpoU rRNA Methylase
257309010922	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
257309010923	active site
257309010924	HMMPfam hit to PF00156, Phosphoribosyl transferase domain
257309010925	1 probable transmembrane helix predicted for DIP2098 by TMHMM2.0
257309010926	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
257309010927	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
257309010928	active site residue [active]
257309010929	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
257309010930	active site residue [active]
257309010931	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309010932	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309010933	HMMPfam hit to PF00581, Rhodanese-like domain
257309010934	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309010935	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309010936	ScanRegExp hit to PS00605, ATP synthase c subunit signature.
257309010937	1 probable transmembrane helix predicted for DIP2100 by TMHMM2.0
257309010938	4 probable transmembrane helices predicted for DIP2102 by TMHMM2.0
257309010939	1 probable transmembrane helix predicted for DIP2103 by TMHMM2.0
257309010940	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
257309010941	Clp amino terminal domain; Region: Clp_N; pfam02861
257309010942	Clp amino terminal domain; Region: Clp_N; pfam02861
257309010943	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309010944	Walker A motif; other site
257309010945	ATP binding site [chemical binding]; other site
257309010946	Walker B motif; other site
257309010947	arginine finger; other site
257309010948	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
257309010949	Walker A motif; other site
257309010950	ATP binding site [chemical binding]; other site
257309010951	Walker B motif; other site
257309010952	arginine finger; other site
257309010953	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
257309010954	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309010955	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010956	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010957	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010958	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010959	ScanRegExp hit to PS00871, Chaperonins clpA/B signature 2.
257309010960	FPrintScan hit to PR00300, ATP-dependent Clp protease ATP-binding subunit signature
257309010961	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010962	HMMPfam hit to PF00004, ATPase associated with various cellular activities (AAA)
257309010963	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010964	ScanRegExp hit to PS00870, Chaperonins clpA/B signature 1.
257309010965	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010966	HMMPfam hit to PF02861, Clp amino terminal domain
257309010967	HMMPfam hit to PF02861, Clp amino terminal domain
257309010968	Transglycosylase-like domain; Region: Transglycosylas; pfam06737
257309010969	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
257309010970	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
257309010971	Walker A/P-loop; other site
257309010972	ATP binding site [chemical binding]; other site
257309010973	Q-loop/lid; other site
257309010974	ABC transporter signature motif; other site
257309010975	Walker B; other site
257309010976	D-loop; other site
257309010977	H-loop/switch region; other site
257309010978	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309010979	HMMPfam hit to PF00005, ABC transporter
257309010980	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309010981	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309010982	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309010983	12 probable transmembrane helices predicted for DIP2107 by TMHMM2.0
257309010984	Na+/glutamate symporter [Amino acid transport and metabolism]; Region: GltS; COG0786
257309010985	13 probable transmembrane helices predicted for DIP2108 by TMHMM2.0
257309010986	HMMPfam hit to PF00999, Sodium/hydrogen exchanger family
257309010987	EamA-like transporter family; Region: EamA; pfam00892
257309010988	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
257309010989	EamA-like transporter family; Region: EamA; pfam00892
257309010990	ProfileScan hit to PS50316, Histidine-rich region.
257309010991	HMMPfam hit to PF00892, Integral membrane protein DUF6
257309010992	10 probable transmembrane helices predicted for DIP2109 by TMHMM2.0
257309010993	HMMPfam hit to PF00892, Integral membrane protein DUF6
257309010994	The oxygenase reductase FAD/NADH binding domain acts as part of the multi-component bacterial oxygenases which oxidize hydrocarbons using oxygen as the oxidant. Electron transfer is from NADH via FAD (in the oxygenase reductase) and an [2FE-2S]...; Region: O2ase_reductase_like; cd06187
257309010995	2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiB; COG0543
257309010996	FAD binding pocket [chemical binding]; other site
257309010997	FAD binding motif [chemical binding]; other site
257309010998	phosphate binding motif [ion binding]; other site
257309010999	beta-alpha-beta structure motif; other site
257309011000	NAD binding pocket [chemical binding]; other site
257309011001	HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain
257309011002	Predicted amidohydrolase [General function prediction only]; Region: COG0388
257309011003	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
257309011004	putative active site [active]
257309011005	catalytic triad [active]
257309011006	putative dimer interface [polypeptide binding]; other site
257309011007	ProfileScan hit to PS50263, Nitrilase/cyanide-hydratase/amidase catalytic domain (active site Cys)
257309011008	HMMPfam hit to PF00795, Carbon-nitrogen hydrolase
257309011009	ScanRegExp hit to PS01227, Uncharacterized protein family UPF0012 signature.
257309011010	Alpha/beta hydrolase; Region: Abhydrolase_8; pfam06259
257309011011	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
257309011012	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
257309011013	NAD binding site [chemical binding]; other site
257309011014	substrate binding site [chemical binding]; other site
257309011015	catalytic Zn binding site [ion binding]; other site
257309011016	tetramer interface [polypeptide binding]; other site
257309011017	structural Zn binding site [ion binding]; other site
257309011018	HMMPfam hit to PF00107, Zinc-binding dehydrogenases
257309011019	ProfileScan hit to PS50205, NAD binding site.
257309011020	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
257309011021	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
257309011022	NAD(P) binding site [chemical binding]; other site
257309011023	catalytic residues [active]
257309011024	HMMPfam hit to PF00171, Aldehyde dehydrogenase
257309011025	ScanRegExp hit to PS00070, Aldehyde dehydrogenases cysteine active site.
257309011026	ScanRegExp hit to PS00687, Aldehyde dehydrogenases glutamic acid active site.
257309011027	1 probable transmembrane helix predicted for DIP2116 by TMHMM2.0
257309011028	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
257309011029	DNA binding residues [nucleotide binding]
257309011030	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
257309011031	putative dimer interface [polypeptide binding]; other site
257309011032	HMMSmart hit to SM00422, helix_turn_helix, mercury resistance
257309011033	FPrintScan hit to PR00040, MerR bacterial regulatory protein HTH signature
257309011034	HMMPfam hit to PF00376, Bacterial regulatory proteins, merR family
257309011035	FPrintScan hit to PR00040, MerR bacterial regulatory protein HTH signature
257309011036	FPrintScan hit to PR00040, MerR bacterial regulatory protein HTH signature
257309011037	chaperone protein DnaJ; Provisional; Region: PRK14279
257309011038	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
257309011039	HSP70 interaction site [polypeptide binding]; other site
257309011040	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
257309011041	Zn binding sites [ion binding]; other site
257309011042	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
257309011043	dimer interface [polypeptide binding]; other site
257309011044	HMMPfam hit to PF01556, DnaJ C terminal region
257309011045	FPrintScan hit to PR00625, DnaJ protein family signature
257309011046	FPrintScan hit to PR00625, DnaJ protein family signature
257309011047	HMMPfam hit to PF00684, DnaJ central domain (4 repeats)
257309011048	FPrintScan hit to PR00625, DnaJ protein family signature
257309011049	FPrintScan hit to PR00625, DnaJ protein family signature
257309011050	FPrintScan hit to PR00625, DnaJ protein family signature
257309011051	ScanRegExp hit to PS00637, CXXCXGXG dnaJ domain signature.
257309011052	FPrintScan hit to PR00625, DnaJ protein family signature
257309011053	ProfileScan hit to PS50315, Glycine-rich region.
257309011054	HMMPfam hit to PF00226, DnaJ domain; ProfileScan hit to PS50076, dnaJ domain profile.
257309011055	FPrintScan hit to PR00625, DnaJ protein family signature
257309011056	HMMSmart hit to SM00271, DnaJ molecular chaperone homology domain
257309011057	FPrintScan hit to PR00625, DnaJ protein family signature
257309011058	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
257309011059	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
257309011060	dimer interface [polypeptide binding]; other site
257309011061	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
257309011062	HMMPfam hit to PF01025, GrpE
257309011063	ScanRegExp hit to PS01071, grpE protein signature.
257309011064	FPrintScan hit to PR00773, GrpE protein signature
257309011065	FPrintScan hit to PR00773, GrpE protein signature
257309011066	FPrintScan hit to PR00773, GrpE protein signature
257309011067	FPrintScan hit to PR00773, GrpE protein signature
257309011068	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
257309011069	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
257309011070	nucleotide binding site [chemical binding]; other site
257309011071	NEF interaction site [polypeptide binding]; other site
257309011072	SBD interface [polypeptide binding]; other site
257309011073	HMMPfam hit to PF00012, Hsp70 protein
257309011074	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011075	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011076	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011077	ScanRegExp hit to PS01036, Heat shock hsp70 proteins family signature 3.
257309011078	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011079	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011080	ScanRegExp hit to PS00329, Heat shock hsp70 proteins family signature 2.
257309011081	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011082	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011083	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011084	FPrintScan hit to PR00301, 70kDa heat shock protein signature
257309011085	ScanRegExp hit to PS00297, Heat shock hsp70 proteins family signature 1.
257309011086	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
257309011087	PAS domain; Region: PAS_9; pfam13426
257309011088	putative active site [active]
257309011089	heme pocket [chemical binding]; other site
257309011090	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
257309011091	Domain of unknown function DUF20; Region: UPF0118; pfam01594
257309011092	8 probable transmembrane helices predicted for DIP2122 by TMHMM2.0
257309011093	HMMPfam hit to PF01594, Domain of unknown function DUF20
257309011094	putative transposase OrfB; Reviewed; Region: PHA02517
257309011095	HTH-like domain; Region: HTH_21; pfam13276
257309011096	Integrase core domain; Region: rve; pfam00665
257309011097	Integrase core domain; Region: rve_2; pfam13333
257309011098	HMMPfam hit to PF00665, Integrase core domain
257309011099	Homeodomain-like domain; Region: HTH_23; cl17451
257309011100	Helix-turn-helix domain; Region: HTH_28; pfam13518
257309011101	Predicted helix-turn-helix motif with score 1129 (+3.03 SD) at aa 28-49, sequence YGSRAVANRLGVRREQVRHLED
257309011102	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309011103	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309011104	Walker A/P-loop; other site
257309011105	ATP binding site [chemical binding]; other site
257309011106	Q-loop/lid; other site
257309011107	ABC transporter signature motif; other site
257309011108	Walker B; other site
257309011109	D-loop; other site
257309011110	H-loop/switch region; other site
257309011111	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011112	HMMPfam hit to PF00005, ABC transporter
257309011113	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011114	FPrintScan hit to PR00988, Uridine kinase signature
257309011115	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011116	FPrintScan hit to PR00988, Uridine kinase signature
257309011117	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011118	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
257309011119	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309011120	dimer interface [polypeptide binding]; other site
257309011121	conserved gate region; other site
257309011122	putative PBP binding loops; other site
257309011123	ABC-ATPase subunit interface; other site
257309011124	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309011125	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
257309011126	Walker A/P-loop; other site
257309011127	ATP binding site [chemical binding]; other site
257309011128	Q-loop/lid; other site
257309011129	ABC transporter signature motif; other site
257309011130	Walker B; other site
257309011131	D-loop; other site
257309011132	H-loop/switch region; other site
257309011133	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
257309011134	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011135	HMMPfam hit to PF00005, ABC transporter
257309011136	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011137	ScanRegExp hit to PS00211, ABC transporters family signature.
257309011138	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011139	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011140	6 probable transmembrane helices predicted for DIP2126 by TMHMM2.0
257309011141	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309011142	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
257309011143	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
257309011144	dimer interface [polypeptide binding]; other site
257309011145	conserved gate region; other site
257309011146	putative PBP binding loops; other site
257309011147	ABC-ATPase subunit interface; other site
257309011148	6 probable transmembrane helices predicted for DIP2127 by TMHMM2.0
257309011149	FPrintScan hit to PR01430, Protease activated receptor 2 precursor signature
257309011150	FPrintScan hit to PR01430, Protease activated receptor 2 precursor signature
257309011151	FPrintScan hit to PR01430, Protease activated receptor 2 precursor signature
257309011152	Predicted helix-turn-helix motif with score 1245 (+3.43 SD) at aa 62-83, sequence AERAKIAAALGVDVPWYHQWLR
257309011153	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
257309011154	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
257309011155	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309011156	ScanRegExp hit to PS01040, Bacterial extracellular solute-binding proteins, family 5 signature.
257309011157	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
257309011158	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
257309011159	12 probable transmembrane helices predicted for DIP2129 by TMHMM2.0
257309011160	HMMPfam hit to PF01384, Phosphate transporter family
257309011161	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
257309011162	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
257309011163	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
257309011164	dimerization interface [polypeptide binding]; other site
257309011165	ATP binding site [chemical binding]; other site
257309011166	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
257309011167	dimerization interface [polypeptide binding]; other site
257309011168	ATP binding site [chemical binding]; other site
257309011169	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
257309011170	putative active site [active]
257309011171	catalytic triad [active]
257309011172	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal domain
257309011173	nucleosidase; Provisional; Region: PRK05634
257309011174	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
257309011175	ferredoxin-NADP+ reductase; Region: PLN02852
257309011176	Permease; Region: Permease; cl00510
257309011177	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
257309011178	4Fe-4S binding domain; Region: Fer4; cl02805
257309011179	Cysteine-rich domain; Region: CCG; pfam02754
257309011180	Cysteine-rich domain; Region: CCG; pfam02754
257309011181	6 probable transmembrane helices predicted for DIP2133 by TMHMM2.0
257309011182	HMMPfam hit to PF00037, 4Fe-4S binding domain
257309011183	ScanRegExp hit to PS00198, 4Fe-4S ferredoxins, iron-sulfur binding region signature.
257309011184	HMMPfam hit to PF00037, 4Fe-4S binding domain
257309011185	ScanRegExp hit to PS00198, 4Fe-4S ferredoxins, iron-sulfur binding region signature.
257309011186	HMMPfam hit to PF02754, Domain of unknown function (DUF224)
257309011187	HMMPfam hit to PF02754, Domain of unknown function (DUF224)
257309011188	FPrintScan hit to PR01217, Proline rich extensin signature
257309011189	ProfileScan hit to PS50310, Alanine-rich region.
257309011190	ProfileScan hit to PS50099, Proline-rich region.
257309011191	FPrintScan hit to PR01217, Proline rich extensin signature
257309011192	FPrintScan hit to PR01217, Proline rich extensin signature
257309011193	FPrintScan hit to PR01217, Proline rich extensin signature
257309011194	FPrintScan hit to PR01217, Proline rich extensin signature
257309011195	Domain of unknown function (DUF1707); Region: DUF1707; pfam08044
257309011196	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
257309011197	(2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233
257309011198	putative NAD(P) binding site [chemical binding]; other site
257309011199	catalytic Zn binding site [ion binding]; other site
257309011200	HMMPfam hit to PF00107, Zinc-binding dehydrogenases
257309011201	ScanRegExp hit to PS00059, Zinc-containing alcohol dehydrogenases signature.
257309011202	aminotransferase AlaT; Validated; Region: PRK09265
257309011203	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
257309011204	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309011205	homodimer interface [polypeptide binding]; other site
257309011206	catalytic residue [active]
257309011207	HMMPfam hit to PF00155, Aminotransferase class I and II
257309011208	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309011209	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309011210	FPrintScan hit to PR00753, 1-aminocyclopropane-1-carboxylate synthase signature
257309011211	YibE/F-like protein; Region: YibE_F; pfam07907
257309011212	8 probable transmembrane helices predicted for DIP2137 by TMHMM2.0
257309011213	lysyl-tRNA synthetase; Provisional; Region: lysS; PRK02983
257309011214	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
257309011215	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
257309011216	dimer interface [polypeptide binding]; other site
257309011217	putative anticodon binding site; other site
257309011218	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
257309011219	motif 1; other site
257309011220	dimer interface [polypeptide binding]; other site
257309011221	active site
257309011222	motif 2; other site
257309011223	motif 3; other site
257309011224	7 probable transmembrane helices predicted for DIP2138 by TMHMM2.0
257309011225	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N)
257309011226	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309011227	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309011228	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309011229	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309011230	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309011231	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature; ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309011232	FPrintScan hit to PR00982, Lysyl-tRNA synthetase signature
257309011233	FPrintScan hit to PR01042, Aspartyl-tRNA synthetase signature
257309011234	ScanRegExp hit to PS00339, Aminoacyl-transfer RNA synthetases class-II signature 2.
257309011235	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
257309011236	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
257309011237	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature
257309011238	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309011239	FPrintScan hit to PR00111, Alpha/beta hydrolase fold signature
257309011240	Protein of unknown function (DUF998); Region: DUF998; pfam06197
257309011241	6 probable transmembrane helices predicted for DIP2140 by TMHMM2.0
257309011242	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
257309011243	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
257309011244	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
257309011245	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase
257309011246	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
257309011247	trimer interface [polypeptide binding]; other site
257309011248	active site
257309011249	HMMPfam hit to PF00692, dUTPase
257309011250	BlastProDom hit to PD004900, PD004900
257309011251	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011252	6 probable transmembrane helices predicted for DIP2143 by TMHMM2.0
257309011253	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309011254	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309011255	Walker A/P-loop; other site
257309011256	ATP binding site [chemical binding]; other site
257309011257	Q-loop/lid; other site
257309011258	ABC transporter signature motif; other site
257309011259	Walker B; other site
257309011260	D-loop; other site
257309011261	H-loop/switch region; other site
257309011262	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011263	HMMPfam hit to PF00005, ABC transporter
257309011264	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011265	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011266	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011267	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
257309011268	2 probable transmembrane helices predicted for DIP2145 by TMHMM2.0
257309011269	Predicted transcriptional regulators [Transcription]; Region: COG1695
257309011270	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
257309011271	Anomalous G+C content (58.19%) and dinucleotide signature.  phage related pathogenicity island. Not present in C.glutamicum
257309011272	Pseudogene. Similar to N-terminal region of Yersinia enterocolitica IS1400 transposase A trp1400A TR:Q9X9H8 (EMBL:AJ132945) (96 aa) fasta scores: E(): 6.9, 32.6% id in 46 aa, and Salmonella enteritidis transposase OrfA TR:O06945 (EMBL:Z83734) (88 aa) fasta scores: E(): 9.1, 42.3% id in 26 aa; transposase fragment (pseudogene)
257309011273	Predicted helix-turn-helix motif with score 1291 (+3.58 SD) at aa 33-54, sequence ITVQQFCKNIGVSKQTYYNIKA
257309011274	Pseudogene. Similar to Mycobacterium tuberculosis transposase Rv3191c or MTV014.35c TR:O53337 (EMBL:AL021646) (344 aa) fasta scores: E(): 1.3e-41, 41.89% id in 327 aa, and to Alcaligenes eutrophus transposase for insertion sequence element IS1086 SW:TRA8_ALCEU (P37248) (339 aa) fasta scores: E(): 2.9e-35, 36.79% id in 329 aa. Presents a frameshift at residue 148 and an in-frame stop codon; transposase (pseudogene)
257309011275	HMMPfam hit to PF00665, Integrase core domain
257309011276	BlastProDom hit to PD002997, PD002997
257309011277	BlastProDom hit to PD002997, PD002997
257309011278	Predicted helix-turn-helix motif with score 1004 (+2.61 SD) at aa 6-27, sequence LGVRAIARHWGRSPGTISKEMT
257309011279	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
257309011280	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
257309011281	active site
257309011282	HMMPfam hit to PF01844, HNH endonuclease
257309011283	HMMSmart hit to SM00507, HNH nucleases
257309011284	Prophage antirepressor [Transcription]; Region: COG3617
257309011285	BRO family, N-terminal domain; Region: Bro-N; smart01040
257309011286	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
257309011287	Predicted helix-turn-helix motif with score 1228 (+3.37 SD) at aa 182-203, sequence LTTTAIAKDYGLSAKKLNRILR
257309011288	HMMPfam hit to PF02498, BRO family, N-terminus
257309011289	Abi-like protein; Region: Abi_2; cl01988
257309011290	Predicted helix-turn-helix motif with score 1396 (+3.94 SD) at aa 211-232, sequence IVRKRIAEPCGLTGPQLESWLK
257309011291	Pseudogene. Similar to C-terminus of Bacteriophage SP02 DNA polymerase L SWALL:DPOL_BPSP2 (SWALL:P06225) (648 aa) fasta scores: E(): 1.3e-34, 50.61% id in 245 aa, and to Xylella fastidiosa phage-related DNA polymerase XF0683 SWALL:Q9PFH5 (EMBL:AE003912) (726 aa) fasta scores: E(): 6e-19, 32.49% id in 277 aa. Presents a frameshift at residue 46; phage DNA polymerase (pseudogene)
257309011292	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309011293	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
257309011294	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309011295	Walker A/P-loop; other site
257309011296	ATP binding site [chemical binding]; other site
257309011297	Q-loop/lid; other site
257309011298	ABC transporter signature motif; other site
257309011299	Walker B; other site
257309011300	D-loop; other site
257309011301	H-loop/switch region; other site
257309011302	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011303	HMMPfam hit to PF00005, ABC transporter
257309011304	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011305	ScanRegExp hit to PS00211, ABC transporters family signature.
257309011306	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011307	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011308	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309011309	4 probable transmembrane helices predicted for DIP2158 by TMHMM2.0
257309011310	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
257309011311	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309011312	Walker A/P-loop; other site
257309011313	ATP binding site [chemical binding]; other site
257309011314	Q-loop/lid; other site
257309011315	ABC transporter signature motif; other site
257309011316	Walker B; other site
257309011317	D-loop; other site
257309011318	H-loop/switch region; other site
257309011319	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011320	HMMPfam hit to PF00005, ABC transporter
257309011321	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011322	ScanRegExp hit to PS00211, ABC transporters family signature.
257309011323	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011324	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011325	6 probable transmembrane helices predicted for DIP2159 by TMHMM2.0
257309011326	HMMPfam hit to PF00664, ABC transporter transmembrane region.
257309011327	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
257309011328	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
257309011329	active site
257309011330	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
257309011331	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
257309011332	Condensation domain; Region: Condensation; pfam00668
257309011333	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
257309011334	Nonribosomal peptide synthase; Region: NRPS; pfam08415
257309011335	Condensation domain; Region: Condensation; pfam00668
257309011336	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
257309011337	Nonribosomal peptide synthase; Region: NRPS; pfam08415
257309011338	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
257309011339	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
257309011340	HMMPfam hit to PF00975, Thioesterase domain
257309011341	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011342	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011343	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309011344	HMMPfam hit to PF00668, Condensation domain
257309011345	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011346	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011347	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309011348	HMMPfam hit to PF00668, Condensation domain
257309011349	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011350	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011351	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309011352	HMMPfam hit to PF00698, Acyl transferase domain
257309011353	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal domain
257309011354	Predicted helix-turn-helix motif with score 1024 (+2.67 SD) at aa 283-304, sequence EVIKEAHAMADISPRQVTYVEG
257309011355	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal domain
257309011356	ScanRegExp hit to PS00606, Beta-ketoacyl synthases active site.
257309011357	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
257309011358	Condensation domain; Region: Condensation; pfam00668
257309011359	Nonribosomal peptide synthase; Region: NRPS; pfam08415
257309011360	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
257309011361	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
257309011362	acyl-activating enzyme (AAE) consensus motif; other site
257309011363	AMP binding site [chemical binding]; other site
257309011364	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
257309011365	Condensation domain; Region: Condensation; pfam00668
257309011366	Nonribosomal peptide synthase; Region: NRPS; pfam08415
257309011367	Phosphopantetheine attachment site; Region: PP-binding; cl09936
257309011368	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011369	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011370	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309011371	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011372	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011373	ScanRegExp hit to PS00012, Phosphopantetheine attachment site.
257309011374	HMMPfam hit to PF00501, AMP-binding enzyme
257309011375	ScanRegExp hit to PS00697, ATP-dependent DNA ligase AMP-binding site.
257309011376	FPrintScan hit to PR00154, AMP-binding signature
257309011377	ScanRegExp hit to PS00455,  AMP-binding domain signature.
257309011378	FPrintScan hit to PR00154, AMP-binding signature
257309011379	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011380	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011381	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
257309011382	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
257309011383	Potential twin-arginine recognition motif RRDFLK
257309011384	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309011385	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309011386	HMMPfam hit to PF00496, Bacterial extracellular solute-binding proteins, family 5
257309011387	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
257309011388	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
257309011389	6 probable transmembrane helices predicted for DIP2163 by TMHMM2.0
257309011390	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309011391	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
257309011392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
257309011393	6 probable transmembrane helices predicted for DIP2164 by TMHMM2.0
257309011394	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component
257309011395	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
257309011396	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
257309011397	Walker A/P-loop; other site
257309011398	ATP binding site [chemical binding]; other site
257309011399	Q-loop/lid; other site
257309011400	ABC transporter signature motif; other site
257309011401	Walker B; other site
257309011402	D-loop; other site
257309011403	H-loop/switch region; other site
257309011404	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309011405	Walker A/P-loop; other site
257309011406	ATP binding site [chemical binding]; other site
257309011407	Q-loop/lid; other site
257309011408	ABC transporter signature motif; other site
257309011409	Walker B; other site
257309011410	D-loop; other site
257309011411	H-loop/switch region; other site
257309011412	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011413	HMMPfam hit to PF00005, ABC transporter
257309011414	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011415	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011416	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011417	ScanRegExp hit to PS00211, ABC transporters family signature.
257309011418	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011419	HMMPfam hit to PF00005, ABC transporter
257309011420	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011421	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011422	ScanRegExp hit to PS00211, ABC transporters family signature.
257309011423	metabolite-proton symporter; Region: 2A0106; TIGR00883
257309011424	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309011425	putative substrate translocation pore; other site
257309011426	HMMPfam hit to PF00083, Sugar (and other) transporter
257309011427	12 probable transmembrane helices predicted for DIP2166 by TMHMM2.0
257309011428	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
257309011429	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
257309011430	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309011431	putative substrate translocation pore; other site
257309011432	HMMPfam hit to PF00083, Sugar (and other) transporter
257309011433	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309011434	11 probable transmembrane helices predicted for DIP2168 by TMHMM2.0
257309011435	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309011436	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309011437	FPrintScan hit to PR01035, Tetracycline resistance protein signature
257309011438	probable transmembrane helix predicted for DIP2169 by TMHMM2.0
257309011439	YwiC-like protein; Region: YwiC; pfam14256
257309011440	5 probable transmembrane helices predicted for DIP2170 by TMHMM2.0
257309011441	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
257309011442	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
257309011443	VanW like protein; Region: VanW; pfam04294
257309011444	1 probable transmembrane helix predicted for DIP2171 by TMHMM2.0
257309011445	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
257309011446	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
257309011447	HMMPfam hit to PF00933, Glycosyl hydrolase 3 N terminal domain
257309011448	ProfileScan hit to PS50324, Serine-rich region.
257309011449	Potential twin-arginine recognition motif RRVFTP
257309011450	Signal peptide predicted for DIP2173 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.715 between residues 41 and 42
257309011451	Protein of unknown function (DUF2613); Region: DUF2613; pfam11021
257309011452	1 probable transmembrane helix predicted for DIP2173 by TMHMM2.0
257309011453	Domain of unknown function (DUF3367); Region: DUF3367; pfam11847
257309011454	12 probable transmembrane helices predicted for DIP2174 by TMHMM2.0
257309011455	ScanRegExp hit to PS00134, Serine proteases, trypsin family, histidine active site.
257309011456	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
257309011457	9 probable transmembrane helices predicted for DIP2175 by TMHMM2.0
257309011458	HMMPfam hit to PF01757, Domain of unknown function DUF33
257309011459	Protein of unknown function (DUF3068); Region: DUF3068; pfam11271
257309011460	2 probable transmembrane helices predicted for DIP2176 by TMHMM2.0
257309011461	8 probable transmembrane helices predicted for DIP2177 by TMHMM2.0
257309011462	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
257309011463	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
257309011464	HMMPfam hit to PF00534, Glycosyl transferases group 1
257309011465	Methyltransferase domain; Region: Methyltransf_31; pfam13847
257309011466	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309011467	S-adenosylmethionine binding site [chemical binding]; other site
257309011468	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309011469	ProfileScan hit to PS50124, Generic methyl-transferase profile.
257309011470	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
257309011471	active site
257309011472	substrate-binding site [chemical binding]; other site
257309011473	metal-binding site [ion binding]
257309011474	GTP binding site [chemical binding]; other site
257309011475	HMMPfam hit to PF00821, Phosphoenolpyruvate carboxykinase
257309011476	BlastProDom hit to PD004738, PD004738
257309011477	ScanRegExp hit to PS00505, Phosphoenolpyruvate carboxykinase (GTP) signature.
257309011478	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
257309011479	S-adenosylmethionine binding site [chemical binding]; other site
257309011480	HMMPfam hit to PF02390,  methyltransferase
257309011481	ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif.
257309011482	LabA_like proteins; Region: LabA_like; cd06167
257309011483	putative metal binding site [ion binding]; other site
257309011484	MMPL family; Region: MMPL; pfam03176
257309011485	MMPL family; Region: MMPL; pfam03176
257309011486	11 probable transmembrane helices predicted for DIP2183 by TMHMM2.0
257309011487	ScanRegExp hit to PS00307, Legume lectins beta-chain signature.
257309011488	Predicted integral membrane protein [Function unknown]; Region: COG0392
257309011489	9 probable transmembrane helices predicted for DIP2184 by TMHMM2.0
257309011490	Protein of unknown function (DUF3054); Region: DUF3054; pfam11255
257309011491	4 probable transmembrane helices predicted for DIP2185 by TMHMM2.0
257309011492	Pseudogene. Partially similar to Corynebacterium xerosis hypothetical 20.7 kDa protein TnpCX TR:Q46485 (EMBL:U21300) (190 aa) fasta scores: E(): 0.0034, 86.36% id in 22 aa; transposon (pseudogene)
257309011493	Pseudogene. Similar to Corynebacterium glutamicum DNA, transposable element IS31831 TR:Q45144 (EMBL:D17429) (436 aa) fasta scores: E(): 0.0028, 65.21% id in 23 aa; transposase (pseudogene)
257309011494	Pseudogene. No significant database matches. Note: Contains a potential sortase anchor site (LAKPG) upstream of the C-terminal region transmembrane domain. Presents a frameshift at residue 322; sortase-substrate protein (pseudogene)
257309011495	1 probable transmembrane helix predicted for DIP2187 by TMHMM2.0
257309011496	potential sortase anchor site LAKTG
257309011497	1 probable transmembrane helix predicted for DIP2187 by TMHMM2.0
257309011498	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
257309011499	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
257309011500	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
257309011501	HMMPfam hit to PF01039, Carboxyl transferase domain
257309011502	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
257309011503	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
257309011504	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
257309011505	active site
257309011506	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
257309011507	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
257309011508	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
257309011509	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
257309011510	HMMPfam hit to PF00975, Thioesterase domain
257309011511	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309011512	ScanRegExp hit to PS00201, Flavodoxin signature.
257309011513	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011514	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011515	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309011516	HMMPfam hit to PF00698, Acyl transferase domain
257309011517	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal domain
257309011518	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal domain
257309011519	ScanRegExp hit to PS00606, Beta-ketoacyl synthases active site.
257309011520	ProfileScan hit to PS50075, Acyl carrier protein phosphopantetheine domain profile.
257309011521	HMMPfam hit to PF00550, Phosphopantetheine attachment site
257309011522	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07769
257309011523	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
257309011524	acyl-activating enzyme (AAE) consensus motif; other site
257309011525	active site
257309011526	HMMPfam hit to PF00501, AMP-binding enzyme
257309011527	Cutinase; Region: Cutinase; pfam01083
257309011528	1 probable transmembrane helix predicted for DIP2191 by TMHMM2.0
257309011529	Putative esterase; Region: Esterase; pfam00756
257309011530	S-formylglutathione hydrolase; Region: PLN02442
257309011531	LGFP repeat; Region: LGFP; pfam08310
257309011532	Uncharacterized protein potentially involved in peptidoglycan biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG5479
257309011533	LGFP repeat; Region: LGFP; pfam08310
257309011534	LGFP repeat; Region: LGFP; pfam08310
257309011535	HMMPfam hit to PF00756,  esterase
257309011536	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309011537	1 probable transmembrane helix predicted for DIP2193 by TMHMM2.0
257309011538	Predicted esterase [General function prediction only]; Region: COG0627
257309011539	S-formylglutathione hydrolase; Region: PLN02442
257309011540	HMMPfam hit to PF00756,  esterase
257309011541	1 probable transmembrane helix predicted for DIP2194 by TMHMM2.0
257309011542	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
257309011543	10 probable transmembrane helices predicted for DIP2195 by TMHMM2.0
257309011544	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
257309011545	UbiA prenyltransferase family; Region: UbiA; pfam01040
257309011546	8 probable transmembrane helices predicted for DIP2196 by TMHMM2.0
257309011547	HMMPfam hit to PF01040, UbiA prenyltransferase
257309011548	HMMPfam hit to PF01569, PAP2 superfamily
257309011549	HMMSmart hit to SM00014, Acid phosphatase homologues
257309011550	ProfileScan hit to PS50226, PA-phosphatase and other phosphomonoesterases.
257309011551	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
257309011552	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
257309011553	ProfileScan hit to PS50167, General Glycosyltransferase domain.
257309011554	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
257309011555	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
257309011556	active site
257309011557	HMMPfam hit to PF01569, PAP2 superfamily
257309011558	4 probable transmembrane helices predicted for DIP2199 by TMHMM2.0
257309011559	HMMSmart hit to SM00014, Acid phosphatase homologues
257309011560	ProfileScan hit to PS50226, PA-phosphatase and other phosphomonoesterases.
257309011561	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
257309011562	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
257309011563	NAD(P) binding site [chemical binding]; other site
257309011564	catalytic residues [active]
257309011565	HMMPfam hit to PF00171, Aldehyde dehydrogenase
257309011566	ScanRegExp hit to PS00070, Aldehyde dehydrogenases cysteine active site.
257309011567	ScanRegExp hit to PS00687, Aldehyde dehydrogenases glutamic acid active site.
257309011568	BCCT family transporter; Region: BCCT; cl00569
257309011569	HMMPfam hit to PF02028, BCCT family transporter
257309011570	BlastProDom hit to PD010111, PD010111
257309011571	12 probable transmembrane helices predicted for DIP2201 by TMHMM2.0
257309011572	HMMPfam hit to PF00732, GMC oxidoreductase
257309011573	choline dehydrogenase; Validated; Region: PRK02106
257309011574	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
257309011575	ScanRegExp hit to PS00623, GMC oxidoreductases signature 1.
257309011576	ScanRegExp hit to PS00624, GMC oxidoreductases signature 2.
257309011577	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
257309011578	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
257309011579	UDP-galactopyranose mutase; Region: GLF; pfam03275
257309011580	Predicted nucleotidyltransferase [General function prediction    only]; Region: COG4849
257309011581	Uncharacterized protein conserved in bacteria (DUF2186); Region: DUF2186; pfam09952
257309011582	Predicted helix-turn-helix motif with score 1432 (+4.06 SD) at aa 160-181, sequence EPVRVIARYSGVSVGTVSNALK
257309011583	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
257309011584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309011585	ABC transporter signature motif; other site
257309011586	Walker B; other site
257309011587	D-loop; other site
257309011588	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011589	Uncharacterized protein potentially involved in peptidoglycan biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG5479
257309011590	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
257309011591	amidase catalytic site [active]
257309011592	Zn binding residues [ion binding]; other site
257309011593	substrate binding site [chemical binding]; other site
257309011594	LGFP repeat; Region: LGFP; pfam08310
257309011595	1 probable transmembrane helix predicted for DIP2207 by TMHMM2.0
257309011596	Anomalous G+C content (50.7%) and dinucleotide signature.  phage related pathogenicity island. Not present in C.glutamicum
257309011597	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
257309011598	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
257309011599	CT1975-like protein; Region: Cas_CT1975; pfam09344
257309011600	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
257309011601	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
257309011602	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
257309011603	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
257309011604	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
257309011605	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309011606	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011607	ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box).
257309011608	HMMPfam hit to PF00271, Helicase conserved C-terminal domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain
257309011609	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
257309011610	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09755
257309011611	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
257309011612	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
257309011613	dimer interface [polypeptide binding]; other site
257309011614	ssDNA binding site [nucleotide binding]; other site
257309011615	tetramer (dimer of dimers) interface [polypeptide binding]; other site
257309011616	HMMPfam hit to PF00436, Single-strand binding protein family
257309011617	Predicted helix-turn-helix motif with score 1110 (+2.97 SD) at aa 43-64, sequence VTNRELAEELPTSERCFIKVFR
257309011618	1 probable transmembrane helix predicted for DIP2223 by TMHMM2.0
257309011619	potential sortase anchor site LGNTG
257309011620	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
257309011621	active site
257309011622	catalytic site [active]
257309011623	2 probable transmembrane helices predicted for DIP2224 by TMHMM2.0
257309011624	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
257309011625	active site
257309011626	catalytic site [active]
257309011627	2 probable transmembrane helices predicted for DIP2225 by TMHMM2.0
257309011628	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
257309011629	probable transmembrane helix predicted for DIP2226 by TMHMM2.0
257309011630	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309011631	potential sortase anchor site LPLTG
257309011632	ProfileScan hit to PS50099, Proline-rich region.
257309011633	Cna protein B-type domain; Region: Cna_B; pfam05738
257309011634	Cna protein B-type domain; Region: Cna_B; pfam05738
257309011635	Cna protein B-type domain; Region: Cna_B; pfam05738
257309011636	Cna protein B-type domain; Region: Cna_B; pfam05738
257309011637	Cna protein B-type domain; Region: Cna_B; pfam05738
257309011638	Cna protein B-type domain; Region: Cna_B; pfam05738
257309011639	probable transmembrane helix predicted for DIP2227 by TMHMM2.0
257309011640	ScanRegExp hit to PS00343, Gram-positive cocci surface proteins 'anchoring' hexapeptide.
257309011641	potential sortase anchor site LPLTG
257309011642	Pseudogene. Similar to Agrobacterium tumefaciens DNA for Ta region of Ti plasmid SWALL:Q44450 (EMBL:X55075) (301 aa) fasta scores: E(): 2.5e-40, 47.47% id in 297 aa, and to Escherichia coli O157:H7 transposase for IS629 Z1957 or ECS1689 SWALL:Q8X587 (EMBL:AE005336) (296 aa) fasta scores: E(): 1e-38, 42.56% id in 289 aa. Presents multiple frameshifts at residues 3, 42, 60, 99, 124, 169, 192, 195, 232 and 243;probable IS element transposase (pseudogene)
257309011643	HMMPfam hit to PF00665, Integrase core domain
257309011644	HMMPfam hit to PF00665, Integrase core domain
257309011645	HMMPfam hit to PF00665, Integrase core domain
257309011646	SdpI/YhfL protein family; Region: SdpI; pfam13630
257309011647	3 probable transmembrane helices predicted for DIP2234 by TMHMM2.0
257309011648	glycerol kinase; Provisional; Region: glpK; PRK00047
257309011649	Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_CsGK_like; cd07789
257309011650	N- and C-terminal domain interface [polypeptide binding]; other site
257309011651	active site
257309011652	MgATP binding site [chemical binding]; other site
257309011653	catalytic site [active]
257309011654	metal binding site [ion binding]; metal-binding site
257309011655	putative homotetramer interface [polypeptide binding]; other site
257309011656	glycerol binding site [chemical binding]; other site
257309011657	homodimer interface [polypeptide binding]; other site
257309011658	HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-terminal domain
257309011659	ScanRegExp hit to PS00445, FGGY family of carbohydrate kinases signature 2.
257309011660	HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-terminal domain
257309011661	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
257309011662	amphipathic channel; other site
257309011663	Asn-Pro-Ala signature motifs; other site
257309011664	6 probable transmembrane helices predicted for DIP2236 by TMHMM2.0
257309011665	FPrintScan hit to PR00783, Major intrinsic protein family signature
257309011666	HMMPfam hit to PF00230, Major intrinsic protein
257309011667	FPrintScan hit to PR00783, Major intrinsic protein family signature
257309011668	FPrintScan hit to PR00783, Major intrinsic protein family signature
257309011669	FPrintScan hit to PR00783, Major intrinsic protein family signature
257309011670	ScanRegExp hit to PS00221, MIP family signature.
257309011671	FPrintScan hit to PR00783, Major intrinsic protein family signature
257309011672	FPrintScan hit to PR00783, Major intrinsic protein family signature
257309011673	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
257309011674	HMMPfam hit to PF01266, FAD dependent oxidoreductase
257309011675	FPrintScan hit to PR01001, FAD-dependent glycerol-3-phosphate dehydrogenase signature
257309011676	FPrintScan hit to PR01001, FAD-dependent glycerol-3-phosphate dehydrogenase signature
257309011677	FPrintScan hit to PR01001, FAD-dependent glycerol-3-phosphate dehydrogenase signature
257309011678	FPrintScan hit to PR01001, FAD-dependent glycerol-3-phosphate dehydrogenase signature
257309011679	ProfileScan hit to PS50205, NAD binding site.
257309011680	FPrintScan hit to PR01001, FAD-dependent glycerol-3-phosphate dehydrogenase signature
257309011681	FPrintScan hit to PR01001, FAD-dependent glycerol-3-phosphate dehydrogenase signature
257309011682	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
257309011683	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
257309011684	putative acyl-acceptor binding pocket; other site
257309011685	ProfileScan hit to PS50326, Valine-rich region.
257309011686	HMMPfam hit to PF01553, Acyltransferase
257309011687	ProfileScan hit to PS50239, Phospholipid and glycerol acyltransferase (from 'motifs_6.msf').
257309011688	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309011689	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
257309011690	active site
257309011691	motif I; other site
257309011692	motif II; other site
257309011693	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
257309011694	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011695	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309011696	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011697	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011698	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011699	seryl-tRNA synthetase; Provisional; Region: PRK05431
257309011700	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
257309011701	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
257309011702	dimer interface [polypeptide binding]; other site
257309011703	active site
257309011704	motif 1; other site
257309011705	motif 2; other site
257309011706	motif 3; other site
257309011707	FPrintScan hit to PR00981, Seryl-tRNA synthetase signature
257309011708	FPrintScan hit to PR00981, Seryl-tRNA synthetase signature
257309011709	FPrintScan hit to PR00981, Seryl-tRNA synthetase signature
257309011710	HMMPfam hit to PF00587, tRNA synthetase class II (G, H, P, S and T)
257309011711	FPrintScan hit to PR00981, Seryl-tRNA synthetase signature
257309011712	ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1.
257309011713	FPrintScan hit to PR00981, Seryl-tRNA synthetase signature
257309011714	HMMPfam hit to PF02403, Seryl-tRNA synthetase N-terminal domain
257309011715	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
257309011716	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309011717	DNA-binding site [nucleotide binding]; DNA binding site
257309011718	UTRA domain; Region: UTRA; pfam07702
257309011719	HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309011720	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family
257309011721	ScanRegExp hit to PS00043, Bacterial regulatory proteins, gntR family signature.
257309011722	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309011723	Predicted helix-turn-helix motif with score 1127 (+3.03 SD) at aa 74-95, sequence PGERALEEQYGVSRITVRRAIG
257309011724	FPrintScan hit to PR00035, GntR bacterial regulatory protein HTH signature
257309011725	Septum formation; Region: Septum_form; pfam13845
257309011726	Septum formation; Region: Septum_form; pfam13845
257309011727	1 probable transmembrane helix predicted for DIP2242 by TMHMM2.0
257309011728	Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein; Region: MMP_ACEL2062; cd12952
257309011729	AAA domain; Region: AAA_14; pfam13173
257309011730	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
257309011731	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011732	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
257309011733	catalytic core [active]
257309011734	HMMPfam hit to PF00300, Phosphoglycerate mutase
257309011735	prephenate dehydratase; Provisional; Region: PRK11898
257309011736	Prephenate dehydratase; Region: PDT; pfam00800
257309011737	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
257309011738	putative L-Phe binding site [chemical binding]; other site
257309011739	HMMPfam hit to PF01842, ACT domain
257309011740	ScanRegExp hit to PS00858, Prephenate dehydratase signature 2.
257309011741	HMMPfam hit to PF00800, Prephenate dehydratase
257309011742	ScanRegExp hit to PS00857, Prephenate dehydratase signature 1.
257309011743	ProfileScan hit to PS50310, Alanine-rich region.
257309011744	Amidase; Region: Amidase; cl11426
257309011745	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
257309011746	HMMPfam hit to PF01425, Amidase
257309011747	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011748	ScanRegExp hit to PS00571, Amidases signature.
257309011749	CAAX protease self-immunity; Region: Abi; pfam02517
257309011750	7 probable transmembrane helices predicted for DIP2248 by TMHMM2.0
257309011751	HMMPfam hit to PF02517, CAAX amino terminal protease
257309011752	Nitric oxide reductase large subunit [Inorganic ion transport and metabolism]; Region: NorB; COG3256
257309011753	14 probable transmembrane helices predicted for DIP2249 by TMHMM2.0
257309011754	ScanRegExp hit to PS00077, Heme-copper oxidase catalytic subunit, copper B binding region signature.
257309011755	Transcriptional regulator [Transcription]; Region: LytR; COG1316
257309011756	1 probable transmembrane helix predicted for DIP2250 by TMHMM2.0
257309011757	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
257309011758	amino acid carrier protein; Region: agcS; TIGR00835
257309011759	HMMPfam hit to PF01235, Sodium:alanine symporter family
257309011760	11 probable transmembrane helices predicted for DIP2251 by TMHMM2.0
257309011761	HMMPfam hit to PF00324, Amino acid permease
257309011762	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309011763	ProfileScan hit to PS50285, Permeases for amino acids and related compounds, family I.
257309011764	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309011765	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309011766	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309011767	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309011768	FPrintScan hit to PR00175, Sodium/alanine symporter signature
257309011769	Acyltransferase family; Region: Acyl_transf_3; pfam01757
257309011770	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
257309011771	catalytic triad [active]
257309011772	catalytic triad [active]
257309011773	oxyanion hole [active]
257309011774	11 probable transmembrane helices predicted for DIP2252 by TMHMM2.0
257309011775	HMMPfam hit to PF01757, Domain of unknown function DUF33
257309011776	HMMPfam hit to PF01757, Domain of unknown function DUF33
257309011777	HMMPfam hit to PF01757, Domain of unknown function DUF33
257309011778	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
257309011779	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_like_2; cd08582
257309011780	putative active site [active]
257309011781	catalytic site [active]
257309011782	putative metal binding site [ion binding]; other site
257309011783	HMMPfam hit to PF03009
257309011784	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
257309011785	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
257309011786	tetramer (dimer of dimers) interface [polypeptide binding]; other site
257309011787	NAD binding site [chemical binding]; other site
257309011788	dimer interface [polypeptide binding]; other site
257309011789	substrate binding site [chemical binding]; other site
257309011790	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-terminal domain
257309011791	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309011792	ScanRegExp hit to PS00064, L-lactate dehydrogenase active site.
257309011793	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309011794	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding domain
257309011795	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309011796	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309011797	ProfileScan hit to PS50205, NAD binding site.
257309011798	FPrintScan hit to PR00086, L-lactate dehydrogenase signature
257309011799	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
257309011800	nudix motif; other site
257309011801	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
257309011802	quinolinate synthetase; Provisional; Region: PRK09375
257309011803	HMMPfam hit to PF02445, Quinolinate synthetase A protein
257309011804	L-aspartate oxidase; Provisional; Region: PRK06175
257309011805	FAD binding domain; Region: FAD_binding_2; pfam00890
257309011806	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309011807	HMMPfam hit to PF00890, FAD binding domain
257309011808	HMMPfam hit to PF00890, FAD binding domain
257309011809	HMMPfam hit to PF00890, FAD binding domain
257309011810	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309011811	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309011812	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
257309011813	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK07896
257309011814	dimerization interface [polypeptide binding]; other site
257309011815	active site
257309011816	HMMPfam hit to PF02749, Quinolinate phosphoribosyl transferase, N-terminal domain
257309011817	HMMPfam hit to PF01729, Quinolinate phosphoribosyl transferase, C-terminal domain
257309011818	methionine sulfoxide reductase A; Provisional; Region: PRK00058
257309011819	HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase
257309011820	BlastProDom hit to PD003489, PD003489
257309011821	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
257309011822	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
257309011823	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
257309011824	HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-hairpin domain
257309011825	BlastProDom hit to PD000475, PD000475
257309011826	HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-terminal domain
257309011827	ScanRegExp hit to PS00088, Manganese and iron superoxide dismutases signature.
257309011828	Predicted flavoprotein [General function prediction only]; Region: COG0431
257309011829	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
257309011830	Protein of unknown function (DUF2029); Region: DUF2029; cl09812
257309011831	11 probable transmembrane helices predicted for DIP2263 by TMHMM2.0
257309011832	Predicted nuclease (RecB family) [General function prediction only]; Region: COG2251
257309011833	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
257309011834	Lsr2; Region: Lsr2; pfam11774
257309011835	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
257309011836	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309011837	active site
257309011838	phosphorylation site [posttranslational modification]
257309011839	intermolecular recognition site; other site
257309011840	dimerization interface [polypeptide binding]; other site
257309011841	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
257309011842	DNA binding residues [nucleotide binding]
257309011843	dimerization interface [polypeptide binding]; other site
257309011844	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family
257309011845	HMMSmart hit to SM00421, helix_turn_helix, Lux Regulon
257309011846	ProfileScan hit to PS50043, Helix-turn-helix domain, luxR and related types (substantial overlap with lysR type).
257309011847	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309011848	ScanRegExp hit to PS00622, Bacterial regulatory proteins, luxR family signature.
257309011849	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309011850	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309011851	HMMPfam hit to PF00072, Response regulator receiver domain
257309011852	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309011853	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309011854	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
257309011855	Histidine kinase; Region: HisKA_3; pfam07730
257309011856	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
257309011857	ATP binding site [chemical binding]; other site
257309011858	Mg2+ binding site [ion binding]; other site
257309011859	G-X-G motif; other site
257309011860	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309011861	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase; HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309011862	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309011863	FPrintScan hit to PR00344, Bacterial sensor protein C-terminal signature
257309011864	5 probable transmembrane helices predicted for DIP2268 by TMHMM2.0
257309011865	Domain of unknown function (DUF2020); Region: DUF2020; pfam09449
257309011866	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
257309011867	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309011868	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309011869	HMMPfam hit to PF00083, Sugar (and other) transporter
257309011870	10 probable transmembrane helices predicted for DIP2270 by TMHMM2.0
257309011871	BlastProDom hit to PD189734, PD189734
257309011872	ScanRegExp hit to PS00942, glpT family of transporters signature.
257309011873	1 probable transmembrane helix predicted for DIP2271 by TMHMM2.0
257309011874	Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_5; cd05830
257309011875	active site
257309011876	catalytic site [active]
257309011877	1 probable transmembrane helix predicted for DIP2272 by TMHMM2.0
257309011878	putative inner membrane protein translocase component YidC; Validated; Region: PRK00247
257309011879	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
257309011880	HMMPfam hit to PF02096, 60Kd inner membrane protein
257309011881	5 probable transmembrane helices predicted for DIP2273 by TMHMM2.0
257309011882	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
257309011883	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
257309011884	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family
257309011885	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309011886	FPrintScan hit to PR00455, TetR bacterial regulatory protein HTH signature
257309011887	3 probable transmembrane helices predicted for DIP2275 by TMHMM2.0
257309011888	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
257309011889	Ligand Binding Site [chemical binding]; other site
257309011890	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
257309011891	Ligand Binding Site [chemical binding]; other site
257309011892	HMMPfam hit to PF00582, Universal stress protein family
257309011893	FPrintScan hit to PR01438, Universal stress protein signature
257309011894	FPrintScan hit to PR01438, Universal stress protein signature
257309011895	FPrintScan hit to PR01438, Universal stress protein signature
257309011896	HMMPfam hit to PF00582, Universal stress protein family
257309011897	Pseudouridine synthase, a subgroup of the RluA family; Region: PSRA_1; cd02558
257309011898	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
257309011899	probable active site [active]
257309011900	BlastProDom hit to PD001819, PD001819
257309011901	HMMPfam hit to PF00849, RNA pseudouridylate synthase
257309011902	ScanRegExp hit to PS01129, Rlu family of pseudouridine synthase signature.
257309011903	10 probable transmembrane helices predicted for DIP2278 by TMHMM2.0
257309011904	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
257309011905	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309011906	Walker A/P-loop; other site
257309011907	ATP binding site [chemical binding]; other site
257309011908	Q-loop/lid; other site
257309011909	ABC transporter signature motif; other site
257309011910	Walker B; other site
257309011911	D-loop; other site
257309011912	H-loop/switch region; other site
257309011913	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011914	HMMPfam hit to PF00005, ABC transporter
257309011915	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309011916	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309011917	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011918	Predicted transcriptional regulators [Transcription]; Region: COG1725
257309011919	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
257309011920	DNA-binding site [nucleotide binding]; DNA binding site
257309011921	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family; HMMSmart hit to SM00345, helix_turn_helix gluconate operon transcriptional repressor, DNA-binding
257309011922	LabA_like proteins; Region: LabA_like; cd06167
257309011923	putative metal binding site [ion binding]; other site
257309011924	Uncharacterized conserved protein [Function unknown]; Region: COG1432
257309011925	ProfileScan hit to PS50310, Alanine-rich region.
257309011926	FPrintScan hit to PR01217, Proline rich extensin signature
257309011927	ProfileScan hit to PS50099, Proline-rich region.
257309011928	FPrintScan hit to PR01217, Proline rich extensin signature
257309011929	FPrintScan hit to PR01217, Proline rich extensin signature
257309011930	FPrintScan hit to PR01217, Proline rich extensin signature
257309011931	FPrintScan hit to PR01217, Proline rich extensin signature
257309011932	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
257309011933	ProfileScan hit to PS50322, Glutamine-rich region.
257309011934	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
257309011935	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
257309011936	catalytic residues [active]
257309011937	HMMPfam hit to PF00085, Thioredoxin
257309011938	ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).
257309011939	FPrintScan hit to PR00421, Thioredoxin family signature
257309011940	FPrintScan hit to PR00421, Thioredoxin family signature
257309011941	FPrintScan hit to PR00421, Thioredoxin family signature
257309011942	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
257309011943	metal-binding site [ion binding]
257309011944	HMMPfam hit to PF00403, Heavy-metal-associated domain
257309011945	ScanRegExp hit to PS01047, Heavy-metal-associated domain.
257309011946	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
257309011947	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
257309011948	metal-binding site [ion binding]
257309011949	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
257309011950	Soluble P-type ATPase [General function prediction only]; Region: COG4087
257309011951	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309011952	HMMPfam hit to PF00403, Heavy-metal-associated domain
257309011953	ScanRegExp hit to PS01047, Heavy-metal-associated domain.
257309011954	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309011955	8 probable transmembrane helices predicted for DIP2286 by TMHMM2.0
257309011956	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309011957	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309011958	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309011959	HMMPfam hit to PF00122, E1-E2 ATPase
257309011960	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309011961	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011962	FPrintScan hit to PR00940, Cation-transporting P-type ATPase A signature
257309011963	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309011964	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309011965	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase
257309011966	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011967	ScanRegExp hit to PS00154, E1-E2 ATPases phosphorylation site.
257309011968	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011969	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011970	FPrintScan hit to PR00120, H+-transporting ATPase (proton pump) signature
257309011971	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309011972	ScanRegExp hit to PS01229, Hypothetical cof family signature 2.
257309011973	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011974	FPrintScan hit to PR00120, H+-transporting ATPase (proton pump) signature
257309011975	FPrintScan hit to PR00119, P-type cation-transporting ATPase superfamily signature
257309011976	FPrintScan hit to PR00120, H+-transporting ATPase (proton pump) signature
257309011977	FPrintScan hit to PR00943, Copper-transporting ATPase signature
257309011978	benzoate transport; Region: 2A0115; TIGR00895
257309011979	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309011980	putative substrate translocation pore; other site
257309011981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
257309011982	HMMPfam hit to PF00083, Sugar (and other) transporter
257309011983	12 probable transmembrane helices predicted for DIP2287 by TMHMM2.0
257309011984	ScanRegExp hit to PS00216, Sugar transport proteins signature 1.
257309011985	ScanRegExp hit to PS00217, Sugar transport proteins signature 2.
257309011986	replicative DNA helicase; Provisional; Region: PRK05636
257309011987	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
257309011988	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
257309011989	Walker A motif; other site
257309011990	ATP binding site [chemical binding]; other site
257309011991	Walker B motif; other site
257309011992	DNA binding loops [nucleotide binding]
257309011993	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309011994	BlastProDom hit to PD002663, PD002663; HMMPfam hit to PF00772, DnaB-like helicase
257309011995	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309011996	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
257309011997	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
257309011998	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
257309011999	HMMPfam hit to PF01281, Ribosomal protein L9
257309012000	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
257309012001	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
257309012002	dimer interface [polypeptide binding]; other site
257309012003	ssDNA binding site [nucleotide binding]; other site
257309012004	tetramer (dimer of dimers) interface [polypeptide binding]; other site
257309012005	ProfileScan hit to PS50315, Glycine-rich region.
257309012006	HMMPfam hit to PF00436, Single-strand binding protein family
257309012007	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
257309012008	HMMPfam hit to PF01250, Ribosomal protein S6
257309012009	ScanRegExp hit to PS01048, Ribosomal protein S6 signature.
257309012010	2 probable transmembrane helices predicted for DIP2292 by TMHMM2.0
257309012011	Predicted integral membrane protein [Function unknown]; Region: COG5650
257309012012	8 probable transmembrane helices predicted for DIP2293 by TMHMM2.0
257309012013	ProfileScan hit to PS50326, Valine-rich region.
257309012014	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
257309012015	Transglycosylase; Region: Transgly; pfam00912
257309012016	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
257309012017	HMMPfam hit to PF00905, Penicillin binding protein transpeptidase domain
257309012018	HMMPfam hit to PF00912, Transglycosylase
257309012019	BlastProDom hit to PD001895, PD001895
257309012020	1 probable transmembrane helix predicted for DIP2294 by TMHMM2.0
257309012021	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
257309012022	MarR family; Region: MarR; pfam01047
257309012023	MarR family; Region: MarR_2; cl17246
257309012024	HMMSmart hit to SM00347, helix_turn_helix multiple antibiotic resistance protein, DNA-binding
257309012025	HMMPfam hit to PF01047, MarR family
257309012026	Predicted helix-turn-helix motif with score 1030 (+2.70 SD) at aa 50-71, sequence ARISHIAQAEGIRMPTASNALH
257309012027	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309012028	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309012029	FPrintScan hit to PR00598, Bacterial regulatory protein MarR family signature
257309012030	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
257309012031	Ligand Binding Site [chemical binding]; other site
257309012032	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
257309012033	Ligand Binding Site [chemical binding]; other site
257309012034	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
257309012035	classical (c) SDRs; Region: SDR_c; cd05233
257309012036	NAD(P) binding site [chemical binding]; other site
257309012037	active site
257309012038	HMMPfam hit to PF00106, short chain dehydrogenase
257309012039	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309012040	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309012041	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309012042	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309012043	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309012044	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309012045	ScanRegExp hit to PS00061, Short-chain dehydrogenases/reductases family signature.
257309012046	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309012047	FPrintScan hit to PR01397, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature
257309012048	FPrintScan hit to PR00081, Glucose/ribitol dehydrogenase signature
257309012049	3 probable transmembrane helices predicted for DIP2299 by TMHMM2.0
257309012050	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
257309012051	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
257309012052	Predicted helix-turn-helix motif with score 1041 (+2.73 SD) at aa 434-455, sequence ASTSELVEASGFSRTAIQRALN
257309012053	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
257309012054	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
257309012055	active site residue [active]
257309012056	ProfileScan hit to PS50206, Rhodanese/cdc25 fold.
257309012057	HMMSmart hit to SM00450, Rhodanese Homology Domain
257309012058	HMMPfam hit to PF00581, Rhodanese-like domain
257309012059	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
257309012060	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
257309012061	4 probable transmembrane helices predicted for DIP2302 by TMHMM2.0
257309012062	HMMPfam hit to PF00597, DedA family
257309012063	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
257309012064	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
257309012065	dimerization interface [polypeptide binding]; other site
257309012066	DPS ferroxidase diiron center [ion binding]; other site
257309012067	ion pore; other site
257309012068	BlastProDom hit to PD149803, PD149803
257309012069	HMMPfam hit to PF02047, Dps protein family
257309012070	FPrintScan hit to PR01346, Helicobacter neutrophil-activating protein A family signature
257309012071	FPrintScan hit to PR01346, Helicobacter neutrophil-activating protein A family signature
257309012072	FPrintScan hit to PR01346, Helicobacter neutrophil-activating protein A family signature; ScanRegExp hit to PS00818, Dps protein family signature 1.
257309012073	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
257309012074	N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases; Region: AcNei1_N; cd08970
257309012075	putative DNA binding site [nucleotide binding]; other site
257309012076	catalytic residue [active]
257309012077	putative H2TH interface [polypeptide binding]; other site
257309012078	putative catalytic residues [active]
257309012079	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
257309012080	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
257309012081	HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase
257309012082	BlastProDom hit to PD003680, PD003680
257309012083	ScanRegExp hit to PS01242, Formamidopyrimidine-DNA glycosylase signature.
257309012084	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
257309012085	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
257309012086	putative substrate binding site [chemical binding]; other site
257309012087	putative ATP binding site [chemical binding]; other site
257309012088	ProfileScan hit to PS50310, Alanine-rich region.
257309012089	HMMPfam hit to PF01256, Uncharacterized protein family UPF0031
257309012090	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cd00599
257309012091	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
257309012092	active site
257309012093	ProfileScan hit to PS50310, Alanine-rich region.
257309012094	BlastProDom hit to PD004620, PD004620
257309012095	1 probable transmembrane helix predicted for DIP2306 by TMHMM2.0
257309012096	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
257309012097	5 probable transmembrane helices predicted for DIP2307 by TMHMM2.0
257309012098	AAA domain; Region: AAA_31; pfam13614
257309012099	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
257309012100	P-loop; other site
257309012101	Magnesium ion binding site [ion binding]; other site
257309012102	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
257309012103	Magnesium ion binding site [ion binding]; other site
257309012104	HMMPfam hit to PF00142, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family
257309012105	FPrintScan hit to PR00091, Nitrogenase component II signature
257309012106	FPrintScan hit to PR00091, Nitrogenase component II signature
257309012107	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
257309012108	Predicted helix-turn-helix motif with score 1046 (+2.75 SD) at aa 270-291, sequence QSFEELLRTTGLSQGQLRFALD
257309012109	Divergent AAA domain; Region: AAA_4; pfam04326
257309012110	Divergent AAA domain; Region: AAA_4; pfam04326
257309012111	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
257309012112	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
257309012113	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
257309012114	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
257309012115	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
257309012116	ATP binding site [chemical binding]; other site
257309012117	putative Mg++ binding site [ion binding]; other site
257309012118	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
257309012119	HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain
257309012120	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
257309012121	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
257309012122	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
257309012123	HMMPfam hit to PF01420, Type I restriction modification DNA specificity domain
257309012124	HMMPfam hit to PF01420, Type I restriction modification DNA specificity domain
257309012125	HsdM N-terminal domain; Region: HsdM_N; pfam12161
257309012126	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
257309012127	Methyltransferase domain; Region: Methyltransf_26; pfam13659
257309012128	HMMPfam hit to PF02384, N-6 DNA Methylase
257309012129	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309012130	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309012131	HMMPfam hit to PF02506, Type I restriction modification system, M protein
257309012132	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309012133	FPrintScan hit to PR00507, N12 class N6 adenine-specific DNA methyltransferase signature
257309012134	Predicted helix-turn-helix motif with score 1049 (+2.76 SD) at aa 8-29, sequence ISMQGIANLAEVKRPAVTQWQT
257309012135	Fic family protein [Function unknown]; Region: COG3177
257309012136	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
257309012137	Fic/DOC family; Region: Fic; pfam02661
257309012138	Predicted helix-turn-helix motif with score 1024 (+2.67 SD) at aa 343-364, sequence VTAKTLERLYGVTWSNARRALE
257309012139	Predicted ATPase of the ABC class; Region: ABC_ATPase; pfam09818
257309012140	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309012141	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
257309012142	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
257309012143	E-class dimer interface [polypeptide binding]; other site
257309012144	P-class dimer interface [polypeptide binding]; other site
257309012145	active site
257309012146	Cu2+ binding site [ion binding]; other site
257309012147	Zn2+ binding site [ion binding]; other site
257309012148	HMMPfam hit to PF00080, Copper/zinc superoxide dismutase (SODC)
257309012149	BlastProDom hit to PD000469, PD000469
257309012150	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
257309012151	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309012152	active site
257309012153	HIGH motif; other site
257309012154	nucleotide binding site [chemical binding]; other site
257309012155	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
257309012156	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309012157	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
257309012158	active site
257309012159	KMSKS motif; other site
257309012160	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
257309012161	tRNA binding surface [nucleotide binding]; other site
257309012162	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V)
257309012163	FPrintScan hit to PR00985, Leucyl-tRNA synthetase signature
257309012164	FPrintScan hit to PR00985, Leucyl-tRNA synthetase signature
257309012165	FPrintScan hit to PR00985, Leucyl-tRNA synthetase signature
257309012166	FPrintScan hit to PR00985, Leucyl-tRNA synthetase signature
257309012167	FPrintScan hit to PR00985, Leucyl-tRNA synthetase signature
257309012168	FPrintScan hit to PR00985, Leucyl-tRNA synthetase signature
257309012169	ScanRegExp hit to PS00178, Aminoacyl-transfer RNA synthetases class-I signature.
257309012170	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
257309012171	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
257309012172	Walker A/P-loop; other site
257309012173	ATP binding site [chemical binding]; other site
257309012174	Q-loop/lid; other site
257309012175	ABC transporter signature motif; other site
257309012176	Walker B; other site
257309012177	D-loop; other site
257309012178	H-loop/switch region; other site
257309012179	HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities
257309012180	HMMPfam hit to PF00005, ABC transporter
257309012181	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309012182	ScanRegExp hit to PS00211, ABC transporters family signature.
257309012183	ProfileScan hit to PS50101, P-loop nucleotide binding motif (does not find all).
257309012184	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309012185	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
257309012186	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
257309012187	HMMPfam hit to PF02687, Predicted permease
257309012188	4 probable transmembrane helices predicted for DIP2324 by TMHMM2.0
257309012189	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309012190	actinobacterial surface-anchored protein domain; Region: P_ac_wall_RPT; TIGR03769
257309012191	1 probable transmembrane helix predicted for DIP2325 by TMHMM2.0
257309012192	potential sortase anchor site LAETG
257309012193	Histidine kinase; Region: HisKA_3; pfam07730
257309012194	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
257309012195	ATP binding site [chemical binding]; other site
257309012196	G-X-G motif; other site
257309012197	5 probable transmembrane helices predicted for DIP2326 by TMHMM2.0
257309012198	HMMSmart hit to SM00387, Histidine kinase-like ATPases
257309012199	ProfileScan hit to PS50109, Bacterial histidine kinase domain.
257309012200	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase
257309012201	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
257309012202	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
257309012203	active site
257309012204	phosphorylation site [posttranslational modification]
257309012205	intermolecular recognition site; other site
257309012206	dimerization interface [polypeptide binding]; other site
257309012207	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
257309012208	DNA binding residues [nucleotide binding]
257309012209	HMMPfam hit to PF00072, Response regulator receiver domain
257309012210	HMMSmart hit to SM00448, cheY-homologous receiver domain
257309012211	ProfileScan hit to PS50110, Histidine-receiving module in bacterial sensor systems.
257309012212	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family
257309012213	HMMSmart hit to SM00421, helix_turn_helix, Lux Regulon
257309012214	ProfileScan hit to PS50043, Helix-turn-helix domain, luxR and related types (substantial overlap with lysR type).
257309012215	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309012216	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309012217	Predicted helix-turn-helix motif with score 1184 (+3.22 SD) at aa 154-175, sequence LSNRQLAAKLFISEATVKTHLV
257309012218	FPrintScan hit to PR00038, LuxR bacterial regulatory protein HTH signature
257309012219	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
257309012220	4 probable transmembrane helices predicted for DIP2328 by TMHMM2.0
257309012221	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
257309012222	Predicted membrane protein [Function unknown]; Region: COG1511
257309012223	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
257309012224	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
257309012225	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
257309012226	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
257309012227	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
257309012228	6 probable transmembrane helices predicted for DIP2329 by TMHMM2.0
257309012229	1 probable transmembrane helix predicted for DIP2330 by TMHMM2.0
257309012230	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
257309012231	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
257309012232	NAD(P) binding site [chemical binding]; other site
257309012233	catalytic residues [active]
257309012234	HMMPfam hit to PF00171, Aldehyde dehydrogenase
257309012235	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
257309012236	active site
257309012237	phosphorylation site [posttranslational modification]
257309012238	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
257309012239	active site
257309012240	P-loop; other site
257309012241	phosphorylation site [posttranslational modification]
257309012242	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
257309012243	BlastProDom hit to PD001689, PD001689
257309012244	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
257309012245	13 probable transmembrane helices predicted for DIP2333 by TMHMM2.0
257309012246	ProfileScan hit to PS50315, Glycine-rich region.
257309012247	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
257309012248	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
257309012249	HMMPfam hit to PF02733, Dak1 domain
257309012250	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
257309012251	HMMPfam hit to PF02734, DAK2 domain
257309012252	ProfileScan hit to PS50310, Alanine-rich region.
257309012253	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
257309012254	active site
257309012255	active pocket/dimerization site; other site
257309012256	phosphorylation site [posttranslational modification]
257309012257	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
257309012258	dimerization domain swap beta strand [polypeptide binding]; other site
257309012259	regulatory protein interface [polypeptide binding]; other site
257309012260	active site
257309012261	regulatory phosphorylation site [posttranslational modification]; other site
257309012262	ProfileScan hit to PS50310, Alanine-rich region.
257309012263	FPrintScan hit to PR00107, Phosphocarrier protein signature
257309012264	ScanRegExp hit to PS00369, PTS HPR component histidine phosphorylation site signature.
257309012265	FPrintScan hit to PR00107, Phosphocarrier protein signature
257309012266	Predicted ATPases [General function prediction only]; Region: COG1106
257309012267	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309012268	RloB-like protein; Region: RloB; pfam13707
257309012269	Putative esterase; Region: Esterase; pfam00756
257309012270	ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine.
257309012271	NH_3: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes...; Region: nuc_hydro_3; cd02653
257309012272	active site
257309012273	HMMPfam hit to PF01156, Inosine-uridine preferring nucleoside hydrolase
257309012274	BlastProDom hit to PD007736, PD007736
257309012275	6 probable transmembrane helices predicted for DIP2341 by TMHMM2.0
257309012276	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
257309012277	4 probable transmembrane helices predicted for DIP2342 by TMHMM2.0
257309012278	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309012279	ABC transporter signature motif; other site
257309012280	Walker B; other site
257309012281	D-loop; other site
257309012282	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
257309012283	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
257309012284	Walker A/P-loop; other site
257309012285	ATP binding site [chemical binding]; other site
257309012286	Q-loop/lid; other site
257309012287	ABC transporter signature motif; other site
257309012288	Walker B; other site
257309012289	D-loop; other site
257309012290	H-loop/switch region; other site
257309012291	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309012292	HMMPfam hit to PF00005, ABC transporter
257309012293	ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
257309012294	ProfileScan hit to PS50100, 2nd half motif for nucleotide binding, associated with P-loop.
257309012295	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
257309012296	active site
257309012297	catalytic residues [active]
257309012298	HMMPfam hit to PF02693, Uncharacterized enzymes related to aldose 1-epimerase
257309012299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
257309012300	hypothetical protein; Provisional; Region: PRK13663
257309012301	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
257309012302	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
257309012303	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family
257309012304	10 probable transmembrane helices predicted for DIP2349 by TMHMM2.0
257309012305	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309012306	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309012307	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309012308	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309012309	FPrintScan hit to PR00173, Glutamate-aspartate symporter signature
257309012310	SdpI/YhfL protein family; Region: SdpI; pfam13630
257309012311	3 probable transmembrane helices predicted for DIP2350 by TMHMM2.0
257309012312	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
257309012313	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
257309012314	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309012315	catalytic residue [active]
257309012316	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme
257309012317	ProfileScan hit to PS50148, Pyridoxalphosphate dependent enzymes.
257309012318	ScanRegExp hit to PS00168, Tryptophan synthase beta chain pyridoxal-phosphate attachment site.
257309012319	anthranilate synthase component I; Provisional; Region: PRK13564
257309012320	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
257309012321	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
257309012322	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
257309012323	HMMPfam hit to PF00425, chorismate binding enzyme
257309012324	BlastProDom hit to PD000779, PD000779
257309012325	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309012326	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309012327	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309012328	FPrintScan hit to PR00095, Anthranilate synthase component I signature
257309012329	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
257309012330	Glutamine amidotransferase class-I; Region: GATase; pfam00117
257309012331	glutamine binding [chemical binding]; other site
257309012332	catalytic triad [active]
257309012333	FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309012334	HMMPfam hit to PF00117, Glutamine amidotransferase class-I
257309012335	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309012336	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309012337	FPrintScan hit to PR00099, Carbamoyl-phosphate synthase GATase domain signature
257309012338	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature; ScanRegExp hit to PS00442, Glutamine amidotransferases class-I active site.
257309012339	FPrintScan hit to PR00096, Glutamine amidotransferase superfamily signature; FPrintScan hit to PR00097, Anthranilate synthase component II signature
257309012340	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
257309012341	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
257309012342	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
257309012343	HMMPfam hit to PF02885, Glycosyl transferase, helical bundle domain
257309012344	BlastProDom hit to PD001864, PD001864
257309012345	HMMPfam hit to PF00591, Glycosyl transferase, a/b domain
257309012346	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
257309012347	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
257309012348	active site
257309012349	ribulose/triose binding site [chemical binding]; other site
257309012350	phosphate binding site [ion binding]; other site
257309012351	substrate (anthranilate) binding pocket [chemical binding]; other site
257309012352	product (indole) binding pocket [chemical binding]; other site
257309012353	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
257309012354	active site
257309012355	BlastProDom hit to PD001511, PD001511; HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase
257309012356	ScanRegExp hit to PS00614, Indole-3-glycerol phosphate synthase signature.
257309012357	HMMPfam hit to PF00697, N-(5'phosphoribosyl)anthranilate (PRA) isomerase
257309012358	DtxR-regulated promoter/operator (Differs in 1 base with the promoter sequence named IRP4 in: Lee et al., Infection and Immunity, (1997)65(10):4273-4280)
257309012359	Protein of unknown function (DUF454); Region: DUF454; cl01063
257309012360	3 probable transmembrane helices predicted for DIP2356 by TMHMM2.0
257309012361	pantoate--beta-alanine ligase; Region: panC; TIGR00018
257309012362	Pantoate-beta-alanine ligase; Region: PanC; cd00560
257309012363	active site
257309012364	ATP-binding site [chemical binding]; other site
257309012365	pantoate-binding site; other site
257309012366	HXXH motif; other site
257309012367	HMMPfam hit to PF02569, Pantoate-beta-alanine ligase
257309012368	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
257309012369	oligomerization interface [polypeptide binding]; other site
257309012370	active site
257309012371	metal binding site [ion binding]; metal-binding site
257309012372	HMMPfam hit to PF02548, Ketopantoate hydroxymethyltransferase
257309012373	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
257309012374	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
257309012375	pyridoxal 5'-phosphate binding site [chemical binding]; other site
257309012376	catalytic residue [active]
257309012377	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme
257309012378	ProfileScan hit to PS50148, Pyridoxalphosphate dependent enzymes.
257309012379	ScanRegExp hit to PS00168, Tryptophan synthase beta chain pyridoxal-phosphate attachment site.
257309012380	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
257309012381	substrate binding site [chemical binding]; other site
257309012382	active site
257309012383	catalytic residues [active]
257309012384	heterodimer interface [polypeptide binding]; other site
257309012385	HMMPfam hit to PF00290, Tryptophan synthase alpha chain
257309012386	BlastProDom hit to PD001535, PD001535
257309012387	ScanRegExp hit to PS00167, Tryptophan synthase alpha chain signature.
257309012388	ProfileScan hit to PS50264, Proteins binding FMN and related compounds (core region profile).
257309012389	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
257309012390	iron-sulfur cluster [ion binding]; other site
257309012391	[2Fe-2S] cluster binding site [ion binding]; other site
257309012392	HMMPfam hit to PF00355, Rieske [2Fe-2S] domain
257309012393	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
257309012394	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
257309012395	9 probable transmembrane helices predicted for DIP2363 by TMHMM2.0
257309012396	HMMPfam hit to PF01758, Sodium Bile acid symporter family
257309012397	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
257309012398	4 probable transmembrane helices predicted for DIP2365 by TMHMM2.0
257309012399	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
257309012400	4 probable transmembrane helices predicted for DIP2366 by TMHMM2.0
257309012401	hypothetical protein; Validated; Region: PRK00228
257309012402	HMMPfam hit to PF02622, Uncharacterized ACR, COG1678
257309012403	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
257309012404	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
257309012405	active site
257309012406	NTP binding site [chemical binding]; other site
257309012407	metal binding triad [ion binding]; metal-binding site
257309012408	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
257309012409	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
257309012410	Zn2+ binding site [ion binding]; other site
257309012411	Mg2+ binding site [ion binding]; other site
257309012412	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
257309012413	HMMPfam hit to PF01966, HD domain
257309012414	HMMPfam hit to PF01743, Poly A polymerase
257309012415	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
257309012416	active site
257309012417	Ap6A binding site [chemical binding]; other site
257309012418	nudix motif; other site
257309012419	metal binding site [ion binding]; metal-binding site
257309012420	ProfileScan hit to PS50323, Arginine-rich region.
257309012421	HMMPfam hit to PF00293, MutT-like domain
257309012422	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309012423	ScanRegExp hit to PS00893, Nudix hydrolase signature.
257309012424	FPrintScan hit to PR00502, NUDIX hydrolase signature
257309012425	1 probable transmembrane helix predicted for DIP2370 by TMHMM2.0
257309012426	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
257309012427	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
257309012428	15 probable transmembrane helices predicted for DIP2371 by TMHMM2.0
257309012429	HMMPfam hit to PF03023
257309012430	ScanRegExp hit to PS00095, C-5 cytosine-specific DNA methylases C-terminal signature.
257309012431	RNA polymerase sigma factor SigM; Reviewed; Region: PRK09643
257309012432	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
257309012433	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
257309012434	DNA binding residues [nucleotide binding]
257309012435	HMMPfam hit to PF00776, Sigma-70 factor (ECF subfamily)
257309012436	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
257309012437	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
257309012438	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
257309012439	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase
257309012440	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature; FPrintScan hit to PR00419, Adrenodoxin reductase signature; FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309012441	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012442	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012443	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012444	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature
257309012445	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012446	ScanRegExp hit to PS00573, Pyridine nucleotide-disulphide oxidoreductases class-II active site.
257309012447	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012448	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309012449	FPrintScan hit to PR00419, Adrenodoxin reductase signature
257309012450	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012451	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309012452	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012453	FPrintScan hit to PR00469, Pyridine nucleotide disulphide reductase class-II signature
257309012454	FPrintScan hit to PR00368, FAD-dependent pyridine nucleotide reductase signature; FPrintScan hit to PR00411, Pyridine nucleotide disulphide reductase class-I signature
257309012455	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
257309012456	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
257309012457	catalytic residues [active]
257309012458	HMMPfam hit to PF00085, Thioredoxin
257309012459	ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).
257309012460	FPrintScan hit to PR00421, Thioredoxin family signature
257309012461	ScanRegExp hit to PS00194, Thioredoxin family active site.
257309012462	FPrintScan hit to PR00421, Thioredoxin family signature
257309012463	FPrintScan hit to PR00421, Thioredoxin family signature
257309012464	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
257309012465	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
257309012466	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
257309012467	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
257309012468	active site
257309012469	metal binding site [ion binding]; metal-binding site
257309012470	HMMPfam hit to PF01471,  peptidoglycan binding domain
257309012471	HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase
257309012472	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
257309012473	ParB-like nuclease domain; Region: ParBc; pfam02195
257309012474	Predicted helix-turn-helix motif with score 1764 (+5.19 SD) at aa 220-241, sequence VTQNELADRLGRSRPVITNMIR
257309012475	HMMPfam hit to PF02195, ParB-like nuclease domain; HMMSmart hit to SM00470, ParB-like nuclease domain
257309012476	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
257309012477	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
257309012478	P-loop; other site
257309012479	Magnesium ion binding site [ion binding]; other site
257309012480	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
257309012481	Magnesium ion binding site [ion binding]; other site
257309012482	HMMPfam hit to PF00991, ParA family ATPase
257309012483	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
257309012484	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
257309012485	HMMPfam hit to PF02527, Glucose inhibited division protein
257309012486	putative inner membrane protein translocase component YidC; Provisional; Region: PRK03449
257309012487	HMMPfam hit to PF02096, 60Kd inner membrane protein
257309012488	5 probable transmembrane helices predicted for DIP2379 by TMHMM2.0
257309012489	ProfileScan hit to PS50320, Methionine-rich region.
257309012490	Pseudogene. Similar to Pseudomonas aeruginosa hypothetical protein PA2045 SW:YK45_PSEAE (Q9I270) (86 aa) fasta scores: E(): 3.2e-13, 50% id in 80 aa, and to Bacillus subtilis hypothetical 8.5 kDa protein in dps-menC intergenic region YtjA SW:YTJA_BACSU (O34601) (75 aa) fasta scores: E(): 3.3e-12, 54.16% id in 72 aa. Possible mutation in start codon from GTG to GTT;Conserved hypothetical protein (pseudogene)
257309012491	HMMPfam hit to PF01809, Domain of unknown function DUF37
257309012492	BlastProDom hit to PD004225, PD004225
257309012493	ribonuclease P; Reviewed; Region: rnpA; PRK03459
257309012494	HMMPfam hit to PF00825, Ribonuclease P
257309012495	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
257309012496	HMMPfam hit to PF00468, Ribosomal protein L34
257309012497	ScanRegExp hit to PS00784, Ribosomal protein L34 signature.
257309012498	dnaA box consensus: TTT(T/C)CAC(C/A)
257309012499	dnaA box consensus: TTT(T/C)CAC(C/A)
257309012500	dnaA box consensus: TTT(T/C)CAC(C/A)
257309012501	dnaA box consensus: TTT(T/C)CAC(C/A)
257309012502	dnaA box consensus: TTT(T/C)CAC(C/A)