-- dump date 20140619_053416 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002332937.1 215918857 7065930 complement(6..119) 1 NC_002971.3 hypothetical protein 119 7065930 CBU_2095a Coxiella burnetii RSA 493 hypothetical protein YP_002332937.1 6 R 227377 CDS NP_819057.1 29653365 1207921 140..1495 1 NC_002971.3 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1495 dnaA 1207921 dnaA Coxiella burnetii RSA 493 chromosome replication initiator DnaA NP_819057.1 140 D 227377 CDS NP_819058.1 29653366 1207922 1639..2748 1 NC_002971.3 DNA polymerase III subunit beta 2748 dnaN 1207922 dnaN Coxiella burnetii RSA 493 DNA polymerase III subunit beta NP_819058.1 1639 D 227377 CDS NP_819059.2 215918858 1207923 2753..3826 1 NC_002971.3 DNA replication and repair protein RecF 3826 recF 1207923 recF Coxiella burnetii RSA 493 DNA replication and repair protein RecF NP_819059.2 2753 D 227377 CDS NP_819060.2 215918859 1207924 4122..6554 1 NC_002971.3 DNA gyrase subunit B 6554 gyrB 1207924 gyrB Coxiella burnetii RSA 493 DNA gyrase subunit B NP_819060.2 4122 D 227377 CDS NP_819062.2 215918860 1207926 6684..7778 1 NC_002971.3 IS1111A transposase 7778 1207926 CBU_0006 Coxiella burnetii RSA 493 IS1111A transposase NP_819062.2 6684 D 227377 CDS YP_002332938.1 215918861 7065897 complement(7775..8047) 1 NC_002971.3 hypothetical protein 8047 7065897 CBU_0006a Coxiella burnetii RSA 493 hypothetical protein YP_002332938.1 7775 R 227377 CDS NP_819063.1 29653371 1207927 complement(8186..8398) 1 NC_002971.3 hypothetical protein 8398 1207927 CBU_0007 Coxiella burnetii RSA 493 hypothetical protein NP_819063.1 8186 R 227377 CDS YP_002332939.1 215918862 7065885 complement(8395..8688) 1 NC_002971.3 hypothetical protein 8688 7065885 CBU_0007a Coxiella burnetii RSA 493 hypothetical protein YP_002332939.1 8395 R 227377 CDS NP_819064.1 29653372 1207928 8716..8904 1 NC_002971.3 hypothetical protein 8904 1207928 CBU_0008 Coxiella burnetii RSA 493 hypothetical protein NP_819064.1 8716 D 227377 CDS YP_002332940.1 215918863 7065949 9006..9560 1 NC_002971.3 hypothetical protein 9560 7065949 CBU_0008a Coxiella burnetii RSA 493 hypothetical protein YP_002332940.1 9006 D 227377 CDS NP_819065.1 29653373 1207871 9560..10993 1 NC_002971.3 D-alanyl-meso-diaminopimelate endopeptidase 10993 dacB 1207871 dacB Coxiella burnetii RSA 493 D-alanyl-meso-diaminopimelate endopeptidase NP_819065.1 9560 D 227377 CDS NP_819066.1 29653374 1207872 10986..11804 1 NC_002971.3 shikimate 5-dehydrogenase 11804 aroE 1207872 aroE Coxiella burnetii RSA 493 shikimate 5-dehydrogenase NP_819066.1 10986 D 227377 CDS NP_819067.1 29653375 1207873 11893..11997 1 NC_002971.3 hypothetical protein 11997 1207873 CBU_0011 Coxiella burnetii RSA 493 hypothetical protein NP_819067.1 11893 D 227377 CDS NP_819070.1 29653378 1207876 complement(13226..14479) 1 NC_002971.3 low-affinity inorganic phosphate transporter 14479 1207876 CBU_0014 Coxiella burnetii RSA 493 low-affinity inorganic phosphate transporter NP_819070.1 13226 R 227377 CDS NP_819071.2 215918864 1207877 14556..15272 1 NC_002971.3 hypothetical protein 15272 1207877 CBU_0015 Coxiella burnetii RSA 493 hypothetical protein NP_819071.2 14556 D 227377 CDS NP_819072.1 29653380 1207878 15274..16095 1 NC_002971.3 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 16095 xapA 1207878 xapA Coxiella burnetii RSA 493 purine nucleoside phosphorylase NP_819072.1 15274 D 227377 CDS NP_819073.1 29653381 1207879 16092..16817 1 NC_002971.3 deoxyribose-phosphate aldolase 16817 deoC 1207879 deoC Coxiella burnetii RSA 493 deoxyribose-phosphate aldolase NP_819073.1 16092 D 227377 CDS NP_819074.1 29653382 1207880 16901..17344 1 NC_002971.3 hypothetical protein 17344 1207880 CBU_0018 Coxiella burnetii RSA 493 hypothetical protein NP_819074.1 16901 D 227377 CDS NP_819075.1 29653383 1207881 complement(17457..17567) 1 NC_002971.3 hypothetical protein 17567 1207881 CBU_0019 Coxiella burnetii RSA 493 hypothetical protein NP_819075.1 17457 R 227377 CDS NP_819076.2 215918865 1207882 complement(17575..18126) 1 NC_002971.3 ribosomal subunit interface protein domain/'cold-shock' DNA-binding domain protein 18126 1207882 CBU_0020 Coxiella burnetii RSA 493 ribosomal subunit interface protein domain/'cold-shock' DNA-binding domain protein NP_819076.2 17575 R 227377 CDS NP_819077.1 29653385 1207883 18337..20766 1 NC_002971.3 hypothetical protein 20766 1207883 CBU_0021 Coxiella burnetii RSA 493 hypothetical protein NP_819077.1 18337 D 227377 CDS NP_819078.1 29653386 1207884 21004..21813 1 NC_002971.3 hypothetical protein 21813 1207884 CBU_0022 Coxiella burnetii RSA 493 hypothetical protein NP_819078.1 21004 D 227377 CDS NP_819079.2 215918866 1207885 complement(21819..22331) 1 NC_002971.3 hypothetical protein 22331 1207885 CBU_0023 Coxiella burnetii RSA 493 hypothetical protein NP_819079.2 21819 R 227377 CDS NP_819080.1 29653388 1207886 complement(22459..22665) 1 NC_002971.3 carbon storage regulator 22665 csrA-1 1207886 csrA-1 Coxiella burnetii RSA 493 carbon storage regulator NP_819080.1 22459 R 227377 CDS NP_819081.1 29653389 1207887 complement(22761..22883) 1 NC_002971.3 hypothetical protein 22883 1207887 CBU_0025 Coxiella burnetii RSA 493 hypothetical protein NP_819081.1 22761 R 227377 CDS NP_819082.1 29653390 1207888 complement(23030..23692) 1 NC_002971.3 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 23692 rpiA 1207888 rpiA Coxiella burnetii RSA 493 ribose-5-phosphate isomerase A NP_819082.1 23030 R 227377 CDS NP_819083.1 29653391 1207889 complement(23834..24724) 1 NC_002971.3 acyltransferase 24724 1207889 CBU_0027 Coxiella burnetii RSA 493 acyltransferase NP_819083.1 23834 R 227377 CDS NP_819084.2 215918867 1207891 complement(26405..27103) 1 NC_002971.3 1-acyl-sn-glycerol-3-phosphate acyltransferase 27103 1207891 CBU_0029 Coxiella burnetii RSA 493 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_819084.2 26405 R 227377 CDS NP_819085.1 29653393 1207892 complement(27090..28277) 1 NC_002971.3 hydroxymethylglutaryl-coenzyme A reductase 28277 1207892 CBU_0030 Coxiella burnetii RSA 493 hydroxymethylglutaryl-coenzyme A reductase NP_819085.1 27090 R 227377 CDS NP_819086.1 29653394 1207893 complement(28376..29314) 1 NC_002971.3 short chain dehydrogenase/reductase oxidoreductase 29314 1207893 CBU_0031 Coxiella burnetii RSA 493 short chain dehydrogenase/reductase oxidoreductase NP_819086.1 28376 R 227377 CDS NP_819087.1 29653395 1207894 29546..29824 1 NC_002971.3 hypothetical protein 29824 1207894 CBU_0032 Coxiella burnetii RSA 493 hypothetical protein NP_819087.1 29546 D 227377 CDS NP_819088.1 29653396 1207895 complement(29917..30618) 1 NC_002971.3 4'-phosphopantetheinyl transferase 30618 1207895 CBU_0033 Coxiella burnetii RSA 493 4'-phosphopantetheinyl transferase NP_819088.1 29917 R 227377 CDS NP_819089.1 29653397 1207896 complement(30622..30882) 1 NC_002971.3 acyl carrier protein 30882 1207896 CBU_0034 Coxiella burnetii RSA 493 acyl carrier protein NP_819089.1 30622 R 227377 CDS NP_819090.1 29653398 1207897 complement(30905..32179) 1 NC_002971.3 beta-ketoacyl-ACP synthase 32179 1207897 CBU_0035 Coxiella burnetii RSA 493 beta-ketoacyl-ACP synthase NP_819090.1 30905 R 227377 CDS NP_819091.1 29653399 1207898 complement(32176..32655) 1 NC_002971.3 beta-hydroxyacyl-ACP dehydratase 32655 1207898 CBU_0036 Coxiella burnetii RSA 493 beta-hydroxyacyl-ACP dehydratase NP_819091.1 32176 R 227377 CDS NP_819092.2 161511219 1207899 complement(32659..33276) 1 NC_002971.3 'catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP'; 3-hydroxydecanoyl-ACP dehydratase 33276 fabA 1207899 fabA Coxiella burnetii RSA 493 3-hydroxydecanoyl-ACP dehydratase NP_819092.2 32659 R 227377 CDS YP_002332941.1 215918868 7065900 33230..33415 1 NC_002971.3 hypothetical protein 33415 7065900 CBU_0037a Coxiella burnetii RSA 493 hypothetical protein YP_002332941.1 33230 D 227377 CDS NP_819093.1 29653401 1207900 complement(33474..34457) 1 NC_002971.3 3-oxoacyl-ACP synthase 34457 1207900 CBU_0038 Coxiella burnetii RSA 493 3-oxoacyl-ACP synthase NP_819093.1 33474 R 227377 CDS NP_819094.1 29653402 1207901 complement(34538..36571) 1 NC_002971.3 oligopeptidase A 36571 prlC 1207901 prlC Coxiella burnetii RSA 493 oligopeptidase A NP_819094.1 34538 R 227377 CDS NP_819095.2 215918869 1207902 36620..37714 1 NC_002971.3 IS1111A transposase 37714 1207902 CBU_0040 Coxiella burnetii RSA 493 IS1111A transposase NP_819095.2 36620 D 227377 CDS YP_002332942.1 215918870 7065911 complement(37711..37983) 1 NC_002971.3 hypothetical protein 37983 7065911 CBU_0040a Coxiella burnetii RSA 493 hypothetical protein YP_002332942.1 37711 R 227377 CDS NP_819096.1 29653404 1207903 complement(38088..40220) 1 NC_002971.3 hypothetical protein 40220 1207903 CBU_0041 Coxiella burnetii RSA 493 hypothetical protein NP_819096.1 38088 R 227377 CDS NP_819097.2 215918871 1207904 complement(40319..41383) 1 NC_002971.3 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 41383 hemH 1207904 hemH Coxiella burnetii RSA 493 ferrochelatase NP_819097.2 40319 R 227377 CDS NP_819098.1 29653406 1207905 41407..42009 1 NC_002971.3 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 42009 1207905 CBU_0043 Coxiella burnetii RSA 493 deoxyribonucleotide triphosphate pyrophosphatase NP_819098.1 41407 D 227377 CDS NP_819099.2 215918872 1207906 42116..42871 1 NC_002971.3 hypothetical protein 42871 1207906 CBU_0044 Coxiella burnetii RSA 493 hypothetical protein NP_819099.2 42116 D 227377 CDS NP_819100.1 29653408 1207907 complement(42968..43528) 1 NC_002971.3 lipoprotein 43528 1207907 CBU_0045 Coxiella burnetii RSA 493 lipoprotein NP_819100.1 42968 R 227377 CDS NP_819101.2 215918873 1207910 complement(45629..46627) 1 NC_002971.3 auxiliary transport protein, membrane fusion protein family 46627 1207910 CBU_0048 Coxiella burnetii RSA 493 auxiliary transport protein, membrane fusion protein family NP_819101.2 45629 R 227377 CDS NP_819102.1 29653410 1207911 complement(46663..47973) 1 NC_002971.3 hypothetical protein 47973 1207911 CBU_0049 Coxiella burnetii RSA 493 hypothetical protein NP_819102.1 46663 R 227377 CDS NP_819103.1 29653411 1207912 complement(48166..48768) 1 NC_002971.3 hypothetical protein 48768 1207912 CBU_0050 Coxiella burnetii RSA 493 hypothetical protein NP_819103.1 48166 R 227377 CDS NP_819104.2 215918874 1207913 complement(48793..49377) 1 NC_002971.3 hypothetical protein 49377 1207913 CBU_0051 Coxiella burnetii RSA 493 hypothetical protein NP_819104.2 48793 R 227377 CDS NP_819106.1 29653414 1207915 49486..50235 1 NC_002971.3 enhanced entry protein 50235 enhA.1 1207915 enhA.1 Coxiella burnetii RSA 493 enhanced entry protein NP_819106.1 49486 D 227377 CDS NP_819107.1 29653415 1207916 50305..50862 1 NC_002971.3 chorismate--pyruvate lyase 50862 1207916 CBU_0054 Coxiella burnetii RSA 493 chorismate--pyruvate lyase NP_819107.1 50305 D 227377 CDS NP_819108.1 29653416 1207917 50855..51718 1 NC_002971.3 4-hydroxybenzoate polyprenyltransferase 51718 ubiA 1207917 ubiA Coxiella burnetii RSA 493 4-hydroxybenzoate polyprenyltransferase NP_819108.1 50855 D 227377 CDS NP_819109.1 29653417 1207918 51830..53680 1 NC_002971.3 TolC family type I secretion outer membrane protein 53680 1207918 CBU_0056 Coxiella burnetii RSA 493 TolC family type I secretion outer membrane protein NP_819109.1 51830 D 227377 CDS NP_819110.1 29653418 1207919 53728..53856 1 NC_002971.3 hypothetical protein 53856 1207919 CBU_0057 Coxiella burnetii RSA 493 hypothetical protein NP_819110.1 53728 D 227377 CDS NP_819111.1 29653419 1207920 53896..53988 1 NC_002971.3 hypothetical protein 53988 1207920 CBU_0058 Coxiella burnetii RSA 493 hypothetical protein NP_819111.1 53896 D 227377 CDS NP_819115.1 29653423 1207932 55870..57375 1 NC_002971.3 DnaJ domain-containing protein 57375 1207932 CBU_0062 Coxiella burnetii RSA 493 DnaJ domain-containing protein NP_819115.1 55870 D 227377 CDS NP_819116.2 215918875 1207933 complement(57361..58668) 1 NC_002971.3 3-deoxy-D-manno-octulosonic-acid transferase 58668 kdtA 1207933 kdtA Coxiella burnetii RSA 493 3-deoxy-D-manno-octulosonic-acid transferase NP_819116.2 57361 R 227377 CDS NP_819117.2 215918876 1207934 58753..60678 1 NC_002971.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 60678 parE 1207934 parE Coxiella burnetii RSA 493 DNA topoisomerase IV subunit B NP_819117.2 58753 D 227377 CDS NP_819118.1 29653426 1207935 60867..61241 1 NC_002971.3 rhodanese domain-containing protein 61241 1207935 CBU_0065 Coxiella burnetii RSA 493 rhodanese domain-containing protein NP_819118.1 60867 D 227377 CDS YP_002332943.1 215918877 7065955 61292..61636 1 NC_002971.3 hypothetical protein 61636 7065955 CBU_0065a Coxiella burnetii RSA 493 hypothetical protein YP_002332943.1 61292 D 227377 CDS NP_819119.1 29653427 1207936 complement(61633..62226) 1 NC_002971.3 5,10-methenyltetrahydrofolate synthetase 62226 1207936 CBU_0066 Coxiella burnetii RSA 493 5,10-methenyltetrahydrofolate synthetase NP_819119.1 61633 R 227377 CDS NP_819120.1 29653428 1207937 complement(62435..62758) 1 NC_002971.3 hypothetical protein 62758 1207937 CBU_0067 Coxiella burnetii RSA 493 hypothetical protein NP_819120.1 62435 R 227377 CDS NP_819121.1 29653429 1207938 complement(62755..62994) 1 NC_002971.3 hypothetical protein 62994 1207938 CBU_0068 Coxiella burnetii RSA 493 hypothetical protein NP_819121.1 62755 R 227377 CDS YP_002332944.1 215918878 7065875 complement(63082..63249) 1 NC_002971.3 hypothetical protein 63249 7065875 CBU_0068a Coxiella burnetii RSA 493 hypothetical protein YP_002332944.1 63082 R 227377 CDS NP_819125.1 29653433 1207942 65611..66810 1 NC_002971.3 ankyrin repeat-containing protein 66810 1207942 CBU_0072 Coxiella burnetii RSA 493 ankyrin repeat-containing protein NP_819125.1 65611 D 227377 CDS NP_819126.2 215918879 1207943 complement(66900..68723) 1 NC_002971.3 peptidase, M24 family 68723 1207943 CBU_0073 Coxiella burnetii RSA 493 peptidase, M24 family NP_819126.2 66900 R 227377 CDS NP_819127.1 29653435 1207944 complement(68781..69002) 1 NC_002971.3 hypothetical protein 69002 1207944 CBU_0074 Coxiella burnetii RSA 493 hypothetical protein NP_819127.1 68781 R 227377 CDS NP_819128.1 29653436 1207945 69001..70233 1 NC_002971.3 2-polyprenyl-6-methoxyphenol 4-hydroxylase 70233 ubiH 1207945 ubiH Coxiella burnetii RSA 493 2-polyprenyl-6-methoxyphenol 4-hydroxylase NP_819128.1 69001 D 227377 CDS NP_819129.2 215918880 1207946 70220..71458 1 NC_002971.3 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 71458 visC 1207946 visC Coxiella burnetii RSA 493 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family NP_819129.2 70220 D 227377 CDS NP_819130.1 29653438 1207947 71573..72364 1 NC_002971.3 hypothetical protein 72364 1207947 CBU_0077 Coxiella burnetii RSA 493 hypothetical protein NP_819130.1 71573 D 227377 CDS NP_819134.1 29653442 1207951 73564..75264 1 NC_002971.3 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 75264 proS 1207951 proS Coxiella burnetii RSA 493 prolyl-tRNA synthetase NP_819134.1 73564 D 227377 CDS NP_819136.2 215918881 1207953 75261..75503 1 NC_002971.3 hypothetical protein 75503 1207953 CBU_0083 Coxiella burnetii RSA 493 hypothetical protein NP_819136.2 75261 D 227377 CDS NP_819137.1 29653445 1207954 75638..77554 1 NC_002971.3 sulfatase 77554 1207954 CBU_0084 Coxiella burnetii RSA 493 sulfatase NP_819137.1 75638 D 227377 CDS NP_819138.1 29653446 1207955 77808..77963 1 NC_002971.3 entericidin B 77963 1207955 CBU_0085 Coxiella burnetii RSA 493 entericidin B NP_819138.1 77808 D 227377 CDS NP_819139.1 29653447 1207956 77974..78732 1 NC_002971.3 amidohydrolase 78732 1207956 CBU_0086 Coxiella burnetii RSA 493 amidohydrolase NP_819139.1 77974 D 227377 CDS NP_819140.2 215918882 1207957 78747..80690 1 NC_002971.3 phosphoglycerol transferase MdoB-like protein 80690 1207957 CBU_0087 Coxiella burnetii RSA 493 phosphoglycerol transferase MdoB-like protein NP_819140.2 78747 D 227377 CDS YP_008992027.1 570699740 1207958 80859..81674 1 NC_002971.3 cell envelope protein TolA; hypothetical protein 81674 1207958 CBU_0088a Coxiella burnetii RSA 493 hypothetical protein YP_008992027.1 80859 D 227377 CDS NP_819141.1 29653449 1207959 81688..81783 1 NC_002971.3 hypothetical protein 81783 1207959 CBU_0089 Coxiella burnetii RSA 493 hypothetical protein NP_819141.1 81688 D 227377 CDS YP_002332945.1 215918883 7065871 81905..82246 1 NC_002971.3 hypothetical protein 82246 7065871 CBU_0089a Coxiella burnetii RSA 493 hypothetical protein YP_002332945.1 81905 D 227377 CDS NP_819142.2 215918884 1207960 82485..83807 1 NC_002971.3 TolB 83807 tolB 1207960 tolB Coxiella burnetii RSA 493 TolB NP_819142.2 82485 D 227377 CDS NP_819143.2 215918885 1207961 83817..84404 1 NC_002971.3 peptidoglycan-associated lipoprotein 84404 1207961 CBU_0091 Coxiella burnetii RSA 493 peptidoglycan-associated lipoprotein NP_819143.2 83817 D 227377 CDS NP_819144.2 215918886 1207962 84391..85308 1 NC_002971.3 tol-pal system protein YbgF 85308 ybgF 1207962 ybgF Coxiella burnetii RSA 493 tol-pal system protein YbgF NP_819144.2 84391 D 227377 CDS NP_819145.1 29653453 1207963 85311..85952 1 NC_002971.3 radical SAM domain-containing protein 85952 queE 1207963 queE Coxiella burnetii RSA 493 radical SAM domain-containing protein NP_819145.1 85311 D 227377 CDS NP_819146.1 29653454 1207964 86265..88844 1 NC_002971.3 ATP-dependent chaperone ClpB 88844 clpB 1207964 clpB Coxiella burnetii RSA 493 ATP-dependent chaperone ClpB NP_819146.1 86265 D 227377 CDS NP_819147.1 29653455 1207965 88841..89809 1 NC_002971.3 sodium-calcium exchanger 89809 1207965 CBU_0095 Coxiella burnetii RSA 493 sodium-calcium exchanger NP_819147.1 88841 D 227377 CDS NP_819148.1 29653456 1207966 complement(89793..90968) 1 NC_002971.3 cardiolipin synthetase 90968 clS 1207966 clS Coxiella burnetii RSA 493 cardiolipin synthetase NP_819148.1 89793 R 227377 CDS YP_002332946.1 215918887 7065976 complement(90968..91360) 1 NC_002971.3 acetyltransferase 91360 7065976 CBU_0095a Coxiella burnetii RSA 493 acetyltransferase YP_002332946.1 90968 R 227377 CDS NP_819149.1 29653457 1207967 91430..92194 1 NC_002971.3 CDP-diacylglycerol--serine O-phosphatidyltransferase 92194 pssA 1207967 pssA Coxiella burnetii RSA 493 CDP-diacylglycerol--serine O-phosphatidyltransferase NP_819149.1 91430 D 227377 CDS NP_819150.1 29653458 1207968 92194..93018 1 NC_002971.3 carboxylating nicotinate-nucleotide pyrophosphorylase 93018 nadC 1207968 nadC Coxiella burnetii RSA 493 carboxylating nicotinate-nucleotide pyrophosphorylase NP_819150.1 92194 D 227377 CDS YP_002332947.1 215918888 7065963 93033..93194 1 NC_002971.3 hypothetical protein 93194 7065963 CBU_0098a Coxiella burnetii RSA 493 hypothetical protein YP_002332947.1 93033 D 227377 CDS YP_002332948.1 215918889 7065950 93486..93692 1 NC_002971.3 hypothetical protein 93692 7065950 CBU_0098b Coxiella burnetii RSA 493 hypothetical protein YP_002332948.1 93486 D 227377 CDS NP_819151.2 215918890 1207971 93683..94162 1 NC_002971.3 phosphohistidine phosphatase SixA 94162 sixA 1207971 sixA Coxiella burnetii RSA 493 phosphohistidine phosphatase SixA NP_819151.2 93683 D 227377 CDS NP_819152.1 29653460 1207972 94164..94565 1 NC_002971.3 lipoprotein 94565 1207972 CBU_0100 Coxiella burnetii RSA 493 lipoprotein NP_819152.1 94164 D 227377 CDS NP_819153.1 29653461 1207973 complement(94519..96129) 1 NC_002971.3 L-aspartate oxidase 96129 nadB 1207973 nadB Coxiella burnetii RSA 493 L-aspartate oxidase NP_819153.1 94519 R 227377 CDS NP_819154.2 215918891 1207974 complement(96250..96363) 1 NC_002971.3 hypothetical protein 96363 1207974 CBU_0102 Coxiella burnetii RSA 493 hypothetical protein NP_819154.2 96250 R 227377 CDS NP_819155.1 29653463 1207975 complement(96398..97840) 1 NC_002971.3 M20/M25/M40 family peptidase 97840 1207975 CBU_0103 Coxiella burnetii RSA 493 M20/M25/M40 family peptidase NP_819155.1 96398 R 227377 CDS NP_819156.1 29653464 1207977 99613..99723 1 NC_002971.3 hypothetical protein 99723 1207977 CBU_0106 Coxiella burnetii RSA 493 hypothetical protein NP_819156.1 99613 D 227377 CDS NP_819157.1 29653465 1207978 100029..101084 1 NC_002971.3 D-methionine ABC transporter ATP-binding protein 101084 1207978 CBU_0107 Coxiella burnetii RSA 493 D-methionine ABC transporter ATP-binding protein NP_819157.1 100029 D 227377 CDS NP_819158.2 215918892 1207979 101107..101709 1 NC_002971.3 D-methionine ABC transporter permease 101709 1207979 CBU_0108 Coxiella burnetii RSA 493 D-methionine ABC transporter permease NP_819158.2 101107 D 227377 CDS NP_819159.1 29653467 1207980 101721..102524 1 NC_002971.3 D-methionine ABC transporter periplasmic D-methionine-binding protein 102524 1207980 CBU_0109 Coxiella burnetii RSA 493 D-methionine ABC transporter periplasmic D-methionine-binding protein NP_819159.1 101721 D 227377 CDS NP_819160.2 215918893 1207981 complement(102535..103020) 1 NC_002971.3 hypothetical protein 103020 1207981 CBU_0110 Coxiella burnetii RSA 493 hypothetical protein NP_819160.2 102535 R 227377 CDS YP_002332949.1 215918894 7065862 complement(103067..103264) 1 NC_002971.3 hypothetical protein 103264 7065862 CBU_0110a Coxiella burnetii RSA 493 hypothetical protein YP_002332949.1 103067 R 227377 CDS NP_819161.1 29653469 1207982 103425..104615 1 NC_002971.3 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 104615 kbl 1207982 kbl Coxiella burnetii RSA 493 2-amino-3-ketobutyrate CoA ligase NP_819161.1 103425 D 227377 CDS NP_819162.1 29653470 1207983 104657..105685 1 NC_002971.3 'converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism'; L-threonine 3-dehydrogenase 105685 tdh 1207983 tdh Coxiella burnetii RSA 493 L-threonine 3-dehydrogenase NP_819162.1 104657 D 227377 CDS NP_819163.1 29653471 1207984 complement(105721..105933) 1 NC_002971.3 hypothetical protein 105933 1207984 CBU_0113 Coxiella burnetii RSA 493 hypothetical protein NP_819163.1 105721 R 227377 CDS NP_819164.1 29653472 1207985 106086..106568 1 NC_002971.3 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 106568 1207985 CBU_0114 Coxiella burnetii RSA 493 nucleotide-binding protein NP_819164.1 106086 D 227377 CDS NP_819165.2 215918895 1207986 106726..107208 1 NC_002971.3 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 107208 mraZ 1207986 mraZ Coxiella burnetii RSA 493 cell division protein MraZ NP_819165.2 106726 D 227377 CDS NP_819166.1 29653474 1207987 107214..108137 1 NC_002971.3 S-adenosyl-methyltransferase MraW 108137 mraW 1207987 mraW Coxiella burnetii RSA 493 S-adenosyl-methyltransferase MraW NP_819166.1 107214 D 227377 CDS NP_819167.1 29653475 1207988 108134..108481 1 NC_002971.3 cell division protein 108481 ftsL 1207988 ftsL Coxiella burnetii RSA 493 cell division protein NP_819167.1 108134 D 227377 CDS NP_819168.2 215918896 1207989 108474..110132 1 NC_002971.3 penicillin-binding protein 110132 pbpB 1207989 pbpB Coxiella burnetii RSA 493 penicillin-binding protein NP_819168.2 108474 D 227377 CDS NP_819169.2 215918897 1207990 complement(110137..111513) 1 NC_002971.3 hypothetical protein 111513 1207990 CBU_0119 Coxiella burnetii RSA 493 hypothetical protein NP_819169.2 110137 R 227377 CDS NP_819171.1 29653479 1207992 complement(111642..111773) 1 NC_002971.3 hypothetical protein 111773 1207992 CBU_0121 Coxiella burnetii RSA 493 hypothetical protein NP_819171.1 111642 R 227377 CDS NP_819172.1 29653480 1207993 111785..112063 1 NC_002971.3 hypothetical protein 112063 1207993 CBU_0122 Coxiella burnetii RSA 493 hypothetical protein NP_819172.1 111785 D 227377 CDS NP_819173.1 29653481 1207994 112114..113583 1 NC_002971.3 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 113583 murE 1207994 murE Coxiella burnetii RSA 493 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase NP_819173.1 112114 D 227377 CDS NP_819174.1 29653482 1207995 113580..114920 1 NC_002971.3 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 114920 murF 1207995 murF Coxiella burnetii RSA 493 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase NP_819174.1 113580 D 227377 CDS NP_819175.1 29653483 1207996 114925..116010 1 NC_002971.3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 116010 mraY 1207996 mraY Coxiella burnetii RSA 493 phospho-N-acetylmuramoyl-pentapeptide- transferase NP_819175.1 114925 D 227377 CDS NP_819177.1 29653485 1207998 116182..116301 1 NC_002971.3 hypothetical protein 116301 1207998 CBU_0127 Coxiella burnetii RSA 493 hypothetical protein NP_819177.1 116182 D 227377 CDS NP_819180.2 215918898 1208001 117802..117981 1 NC_002971.3 hypothetical protein 117981 1208001 CBU_0130 Coxiella burnetii RSA 493 hypothetical protein NP_819180.2 117802 D 227377 CDS NP_819181.1 29653489 1208002 118036..119364 1 NC_002971.3 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 119364 murD 1208002 murD Coxiella burnetii RSA 493 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_819181.1 118036 D 227377 CDS NP_819182.1 29653490 1208003 119364..120482 1 NC_002971.3 cell division protein 120482 ftsW 1208003 ftsW Coxiella burnetii RSA 493 cell division protein NP_819182.1 119364 D 227377 CDS NP_819185.1 29653493 1208006 122082..123158 1 NC_002971.3 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 123158 murG 1208006 murG Coxiella burnetii RSA 493 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_819185.1 122082 D 227377 CDS NP_819186.1 29653494 1208007 123145..124542 1 NC_002971.3 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 124542 murC 1208007 murC Coxiella burnetii RSA 493 UDP-N-acetylmuramate--L-alanine ligase NP_819186.1 123145 D 227377 CDS NP_819187.1 29653495 1208008 124535..125485 1 NC_002971.3 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 125485 murB 1208008 murB Coxiella burnetii RSA 493 UDP-N-acetylenolpyruvoylglucosamine reductase NP_819187.1 124535 D 227377 CDS NP_819188.1 29653496 1208009 125485..126216 1 NC_002971.3 cell division protein 126216 ftsQ 1208009 ftsQ Coxiella burnetii RSA 493 cell division protein NP_819188.1 125485 D 227377 CDS NP_819189.1 29653497 1208010 complement(126213..126833) 1 NC_002971.3 carbonate dehydratase 126833 1208010 CBU_0139 Coxiella burnetii RSA 493 carbonate dehydratase NP_819189.1 126213 R 227377 CDS NP_819190.2 215918899 1208011 127015..128256 1 NC_002971.3 cell division protein 128256 ftsA 1208011 ftsA Coxiella burnetii RSA 493 cell division protein NP_819190.2 127015 D 227377 CDS NP_819191.2 215918900 1208012 128257..129438 1 NC_002971.3 'GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function'; cell division protein FtsZ 129438 ftsZ 1208012 ftsZ Coxiella burnetii RSA 493 cell division protein FtsZ NP_819191.2 128257 D 227377 CDS NP_819192.1 29653500 1208013 129598..130509 1 NC_002971.3 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 130509 lpxC 1208013 lpxC Coxiella burnetii RSA 493 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_819192.1 129598 D 227377 CDS NP_819193.1 29653501 1208014 complement(130815..130946) 1 NC_002971.3 hypothetical protein 130946 1208014 CBU_0143 Coxiella burnetii RSA 493 hypothetical protein NP_819193.1 130815 R 227377 CDS NP_819196.2 215918901 1208017 complement(132416..132760) 1 NC_002971.3 hypothetical protein 132760 1208017 CBU_0146 Coxiella burnetii RSA 493 hypothetical protein NP_819196.2 132416 R 227377 CDS NP_819197.2 215918902 1208018 132760..135510 1 NC_002971.3 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 135510 secA 1208018 secA Coxiella burnetii RSA 493 preprotein translocase subunit SecA NP_819197.2 132760 D 227377 CDS NP_819198.1 29653506 1208019 135489..135902 1 NC_002971.3 7,8-dihydro-8-oxoguanine-triphosphatase 135902 mutT 1208019 mutT Coxiella burnetii RSA 493 7,8-dihydro-8-oxoguanine-triphosphatase NP_819198.1 135489 D 227377 CDS NP_819199.1 29653507 1208020 135899..136045 1 NC_002971.3 hypothetical protein 136045 1208020 CBU_0149 Coxiella burnetii RSA 493 hypothetical protein NP_819199.1 135899 D 227377 CDS NP_819200.2 215918903 1208021 complement(136270..137082) 1 NC_002971.3 hypothetical protein 137082 1208021 CBU_0150 Coxiella burnetii RSA 493 hypothetical protein NP_819200.2 136270 R 227377 CDS NP_819201.1 29653509 1208022 complement(137107..137943) 1 NC_002971.3 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 137943 queF 1208022 queF Coxiella burnetii RSA 493 7-cyano-7-deazaguanine reductase NP_819201.1 137107 R 227377 CDS NP_819202.1 29653510 1208023 complement(137964..138563) 1 NC_002971.3 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 138563 coaE 1208023 coaE Coxiella burnetii RSA 493 dephospho-CoA kinase NP_819202.1 137964 R 227377 CDS NP_819203.1 29653511 1208024 complement(138574..139434) 1 NC_002971.3 type 4 prepilin peptidase 139434 pilD 1208024 pilD Coxiella burnetii RSA 493 type 4 prepilin peptidase NP_819203.1 138574 R 227377 CDS NP_819204.1 29653512 1208025 complement(139460..140515) 1 NC_002971.3 type 4 pili biogenesis protein (plasma membrane protein) 140515 pilC 1208025 pilC Coxiella burnetii RSA 493 type 4 pili biogenesis protein (plasma membrane protein) NP_819204.1 139460 R 227377 CDS NP_819205.1 29653513 1208026 complement(140508..142061) 1 NC_002971.3 type 4 pili biogenesis protein (nuleotide-binding protein) 142061 pilB 1208026 pilB Coxiella burnetii RSA 493 type 4 pili biogenesis protein (nuleotide-binding protein) NP_819205.1 140508 R 227377 CDS NP_819206.1 29653514 1208027 complement(142051..142473) 1 NC_002971.3 type IV-A pilin protein PilA 142473 pilA 1208027 pilA Coxiella burnetii RSA 493 type IV-A pilin protein PilA NP_819206.1 142051 R 227377 CDS YP_002332950.1 215918904 7065870 complement(142721..142882) 1 NC_002971.3 phage integrase 142882 7065870 CBU_0156a Coxiella burnetii RSA 493 phage integrase YP_002332950.1 142721 R 227377 CDS NP_819207.1 29653515 1208029 complement(143025..143126) 1 NC_002971.3 hypothetical protein 143126 1208029 CBU_0157 Coxiella burnetii RSA 493 hypothetical protein NP_819207.1 143025 R 227377 CDS NP_819208.1 29653516 1208030 complement(143123..143680) 1 NC_002971.3 CRISPR-associated Csy4 family protein 143680 1208030 CBU_0158 Coxiella burnetii RSA 493 CRISPR-associated Csy4 family protein NP_819208.1 143123 R 227377 CDS NP_819209.2 215918905 1208031 complement(143689..144798) 1 NC_002971.3 CRISPR-associated Cas5e family protein 144798 1208031 CBU_0159 Coxiella burnetii RSA 493 CRISPR-associated Cas5e family protein NP_819209.2 143689 R 227377 CDS YP_008994789.1 570699743 18126240 complement(147255..148829) 1 NC_002971.3 hypothetical protein 148829 18126240 CB_0162 Coxiella burnetii RSA 493 hypothetical protein YP_008994789.1 147255 R 227377 CDS NP_819211.1 29653519 1208037 complement(151693..152283) 1 NC_002971.3 hypothetical protein 152283 1208037 CBU_0165 Coxiella burnetii RSA 493 hypothetical protein NP_819211.1 151693 R 227377 CDS NP_819212.1 29653520 1208038 complement(152294..153058) 1 NC_002971.3 hypothetical protein 153058 1208038 CBU_0166 Coxiella burnetii RSA 493 hypothetical protein NP_819212.1 152294 R 227377 CDS NP_819213.1 29653521 1208039 153046..153609 1 NC_002971.3 enoyl-CoA hydratase 153609 pksH 1208039 pksH Coxiella burnetii RSA 493 enoyl-CoA hydratase NP_819213.1 153046 D 227377 CDS NP_819214.1 29653522 1208040 153755..154033 1 NC_002971.3 'Acyl carrier proteins are involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; this ACP may be involved in the biosynthesis of lipopeptide antibiotics'; acyl carrier protein 154033 1208040 CBU_0168 Coxiella burnetii RSA 493 acyl carrier protein NP_819214.1 153755 D 227377 CDS NP_819219.1 29653527 1208045 complement(155654..156106) 1 NC_002971.3 hypothetical protein 156106 1208045 CBU_0173 Coxiella burnetii RSA 493 hypothetical protein NP_819219.1 155654 R 227377 CDS NP_819221.1 29653529 1208047 156814..157554 1 NC_002971.3 serine/threonine kinase 157554 1208047 CBU_0175 Coxiella burnetii RSA 493 serine/threonine kinase NP_819221.1 156814 D 227377 CDS NP_819222.1 29653530 1208048 157619..158806 1 NC_002971.3 serine protease domain-containing protein 158806 degP.1 1208048 degP.1 Coxiella burnetii RSA 493 serine protease domain-containing protein NP_819222.1 157619 D 227377 CDS NP_819223.2 215918906 1208049 complement(158815..160395) 1 NC_002971.3 quaternary amine ABC transporter permease/periplasmic amine-binding protein 160395 1208049 CBU_0177 Coxiella burnetii RSA 493 quaternary amine ABC transporter permease/periplasmic amine-binding protein NP_819223.2 158815 R 227377 CDS NP_819224.1 29653532 1208050 complement(160392..161150) 1 NC_002971.3 quaternary amine ABC transporter ATP-binding protein 161150 1208050 CBU_0178 Coxiella burnetii RSA 493 quaternary amine ABC transporter ATP-binding protein NP_819224.1 160392 R 227377 CDS NP_819225.1 29653533 1208051 complement(161197..162315) 1 NC_002971.3 'catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling'; anhydro-N-acetylmuramic acid kinase 162315 anmK 1208051 anmK Coxiella burnetii RSA 493 anhydro-N-acetylmuramic acid kinase NP_819225.1 161197 R 227377 CDS NP_819226.2 215918907 1208052 complement(162319..163677) 1 NC_002971.3 peptidase M23/M37 domain-containing protein 163677 1208052 CBU_0180 Coxiella burnetii RSA 493 peptidase M23/M37 domain-containing protein NP_819226.2 162319 R 227377 CDS NP_819227.1 29653535 1208053 163701..164900 1 NC_002971.3 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 164900 tyrS 1208053 tyrS Coxiella burnetii RSA 493 tyrosyl-tRNA synthetase NP_819227.1 163701 D 227377 CDS YP_002332951.1 215918908 7065867 complement(164937..165194) 1 NC_002971.3 hypothetical protein 165194 7065867 CBU_0181a Coxiella burnetii RSA 493 hypothetical protein YP_002332951.1 164937 R 227377 CDS YP_022738.1 47778683 2820718 168770..169138 1 NC_002971.3 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown; hypothetical protein 169138 2820718 CBU_2096 Coxiella burnetii RSA 493 hypothetical protein YP_022738.1 168770 D 227377 CDS NP_819228.1 29653536 1208057 170459..170932 1 NC_002971.3 homing endonuclease, 23S rRNA intron 170932 1208057 CBU_0182 Coxiella burnetii RSA 493 homing endonuclease, 23S rRNA intron NP_819228.1 170459 D 227377 CDS NP_819229.2 215918909 1208059 172242..172514 1 NC_002971.3 hypothetical protein 172514 1208059 CBU_0183 Coxiella burnetii RSA 493 hypothetical protein NP_819229.2 172242 D 227377 CDS NP_819230.1 29653538 1208060 complement(172597..173757) 1 NC_002971.3 hypothetical protein 173757 1208060 CBU_0184 Coxiella burnetii RSA 493 hypothetical protein NP_819230.1 172597 R 227377 CDS NP_819239.2 215918910 1208069 178601..179812 1 NC_002971.3 hypothetical protein 179812 1208069 CBU_0193 Coxiella burnetii RSA 493 hypothetical protein NP_819239.2 178601 D 227377 CDS NP_819240.1 29653548 1208070 complement(179840..181207) 1 NC_002971.3 L-serine ammonia-lyase 181207 sda 1208070 sda Coxiella burnetii RSA 493 L-serine ammonia-lyase NP_819240.1 179840 R 227377 CDS NP_819241.1 29653549 1208071 181388..182689 1 NC_002971.3 AmpG 182689 ampG 1208071 ampG Coxiella burnetii RSA 493 AmpG NP_819241.1 181388 D 227377 CDS NP_819242.1 29653550 1208072 182776..182988 1 NC_002971.3 hypothetical protein 182988 1208072 CBU_0196 Coxiella burnetii RSA 493 hypothetical protein NP_819242.1 182776 D 227377 CDS NP_819243.1 29653551 1208073 complement(183058..185847) 1 NC_002971.3 hypothetical protein 185847 1208073 CBU_0197 Coxiella burnetii RSA 493 hypothetical protein NP_819243.1 183058 R 227377 CDS NP_819244.1 29653552 1208074 complement(185844..187580) 1 NC_002971.3 hypothetical protein 187580 1208074 CBU_0198 Coxiella burnetii RSA 493 hypothetical protein NP_819244.1 185844 R 227377 CDS NP_819245.1 29653553 1208075 187721..188677 1 NC_002971.3 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 188677 coaA 1208075 coaA Coxiella burnetii RSA 493 pantothenate kinase NP_819245.1 187721 D 227377 CDS NP_819246.2 215918911 1208076 188678..189565 1 NC_002971.3 aldose 1-epimerase 189565 1208076 CBU_0200 Coxiella burnetii RSA 493 aldose 1-epimerase NP_819246.2 188678 D 227377 CDS NP_819247.1 29653555 1208077 complement(189646..190041) 1 NC_002971.3 ankyrin repeat-containing protein 190041 1208077 CBU_0201 Coxiella burnetii RSA 493 ankyrin repeat-containing protein NP_819247.1 189646 R 227377 CDS NP_819251.2 215918912 1208081 190941..192362 1 NC_002971.3 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 192362 gltX 1208081 gltX Coxiella burnetii RSA 493 glutamyl-tRNA synthetase NP_819251.2 190941 D 227377 CDS NP_819252.1 29653560 1208082 192424..192816 1 NC_002971.3 hypothetical protein 192816 1208082 CBU_0206 Coxiella burnetii RSA 493 hypothetical protein NP_819252.1 192424 D 227377 CDS NP_819253.2 215918913 1208084 193066..193371 1 NC_002971.3 hypothetical protein 193371 1208084 CBU_0207 Coxiella burnetii RSA 493 hypothetical protein NP_819253.2 193066 D 227377 CDS NP_819254.1 29653562 1208086 194626..195606 1 NC_002971.3 hypothetical protein 195606 1208086 CBU_0209 Coxiella burnetii RSA 493 hypothetical protein NP_819254.1 194626 D 227377 CDS NP_819255.1 29653563 1208087 195585..195722 1 NC_002971.3 hypothetical protein 195722 1208087 CBU_0210 Coxiella burnetii RSA 493 hypothetical protein NP_819255.1 195585 D 227377 CDS NP_819258.1 29653566 1208090 complement(197402..197560) 1 NC_002971.3 hypothetical protein 197560 1208090 CBU_0213 Coxiella burnetii RSA 493 hypothetical protein NP_819258.1 197402 R 227377 CDS NP_819259.1 29653567 1208091 197944..198663 1 NC_002971.3 hypothetical protein 198663 1208091 CBU_0214 Coxiella burnetii RSA 493 hypothetical protein NP_819259.1 197944 D 227377 CDS NP_819260.2 215918914 1208092 complement(198718..200316) 1 NC_002971.3 peptidase, C40 family; NlpC-P60 family protein 200316 1208092 CBU_0215 Coxiella burnetii RSA 493 NlpC-P60 family protein NP_819260.2 198718 R 227377 CDS YP_002332952.1 215918915 7065970 201949..202089 1 NC_002971.3 hypothetical protein 202089 7065970 CBU_0217a Coxiella burnetii RSA 493 hypothetical protein YP_002332952.1 201949 D 227377 CDS NP_819263.1 29653571 1208095 202174..203724 1 NC_002971.3 cytochrome d ubiquinol oxidase subunit I 203724 cydA-1 1208095 cydA-1 Coxiella burnetii RSA 493 cytochrome d ubiquinol oxidase subunit I NP_819263.1 202174 D 227377 CDS YP_008992028.1 570699737 1208096 203733..204896 1 NC_002971.3 cytochrome BD oxidase subunit II 204896 1208096 CBU_0220a Coxiella burnetii RSA 493 cytochrome BD oxidase subunit II YP_008992028.1 203733 D 227377 CDS NP_819264.1 29653572 1208097 204884..205003 1 NC_002971.3 hypothetical protein 205003 1208097 CBU_0220 Coxiella burnetii RSA 493 hypothetical protein NP_819264.1 204884 D 227377 CDS NP_819265.1 29653573 1208098 204996..205727 1 NC_002971.3 phosphopantethiene-protein transferase domain-contain protein 205727 1208098 CBU_0221 Coxiella burnetii RSA 493 phosphopantethiene-protein transferase domain-contain protein NP_819265.1 204996 D 227377 CDS YP_002332953.1 215918916 7065947 205996..206112 1 NC_002971.3 hypothetical protein 206112 7065947 CBU_0221a Coxiella burnetii RSA 493 hypothetical protein YP_002332953.1 205996 D 227377 CDS YP_002332954.1 215918917 1208103 206314..207507 1 NC_002971.3 'EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu'; elongation factor Tu 207507 1208103 CBU_0221b Coxiella burnetii RSA 493 elongation factor Tu YP_002332954.1 206314 D 227377 CDS NP_819268.1 29653576 1208105 207752..208135 1 NC_002971.3 protein translocase subunit 208135 secE 1208105 secE Coxiella burnetii RSA 493 protein translocase subunit NP_819268.1 207752 D 227377 CDS NP_819269.2 215918918 1208106 208160..208726 1 NC_002971.3 transcription termination/antitermination factor NusG 208726 nusG 1208106 nusG Coxiella burnetii RSA 493 transcription termination/antitermination factor NusG NP_819269.2 208160 D 227377 CDS NP_819270.1 29653578 1208107 208851..209288 1 NC_002971.3 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 209288 rplK 1208107 rplK Coxiella burnetii RSA 493 50S ribosomal protein L11 NP_819270.1 208851 D 227377 CDS NP_819271.1 29653579 1208108 209288..209986 1 NC_002971.3 'in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA'; 50S ribosomal protein L1 209986 rplA 1208108 rplA Coxiella burnetii RSA 493 50S ribosomal protein L1 NP_819271.1 209288 D 227377 CDS NP_819272.1 29653580 1208109 210240..210764 1 NC_002971.3 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 210764 rplJ 1208109 rplJ Coxiella burnetii RSA 493 50S ribosomal protein L10 NP_819272.1 210240 D 227377 CDS NP_819273.1 29653581 1208110 210798..211178 1 NC_002971.3 'present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors'; 50S ribosomal protein L7/L12 211178 rplL 1208110 rplL Coxiella burnetii RSA 493 50S ribosomal protein L7/L12 NP_819273.1 210798 D 227377 CDS NP_819274.1 29653582 1208111 211191..211310 1 NC_002971.3 hypothetical protein 211310 1208111 CBU_0230 Coxiella burnetii RSA 493 hypothetical protein NP_819274.1 211191 D 227377 CDS NP_819275.2 215918919 1208112 211325..215458 1 NC_002971.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 215458 rpoB 1208112 rpoB Coxiella burnetii RSA 493 DNA-directed RNA polymerase subunit beta NP_819275.2 211325 D 227377 CDS NP_819276.1 29653584 1208113 215727..219971 1 NC_002971.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 219971 rpoC 1208113 rpoC Coxiella burnetii RSA 493 DNA-directed RNA polymerase subunit beta' NP_819276.1 215727 D 227377 CDS NP_819277.2 215918920 1208114 220265..220687 1 NC_002971.3 'interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance'; 30S ribosomal protein S12 220687 rpsL 1208114 rpsL Coxiella burnetii RSA 493 30S ribosomal protein S12 NP_819277.2 220265 D 227377 CDS NP_819278.1 29653586 1208115 220700..221275 1 NC_002971.3 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 221275 rpsG 1208115 rpsG Coxiella burnetii RSA 493 30S ribosomal protein S7 NP_819278.1 220700 D 227377 CDS NP_819279.1 29653587 1208116 221285..223384 1 NC_002971.3 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 223384 fusA 1208116 fusA Coxiella burnetii RSA 493 elongation factor G NP_819279.1 221285 D 227377 CDS NP_819280.1 29653588 1208117 223400..224593 1 NC_002971.3 'EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu'; elongation factor Tu 224593 tuf-2 1208117 tuf-2 Coxiella burnetii RSA 493 elongation factor Tu NP_819280.1 223400 D 227377 CDS NP_819281.2 215918921 1208118 224774..225115 1 NC_002971.3 'NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex'; 30S ribosomal protein S10 225115 rpsJ 1208118 rpsJ Coxiella burnetii RSA 493 30S ribosomal protein S10 NP_819281.2 224774 D 227377 CDS NP_819282.1 29653590 1208119 225137..225790 1 NC_002971.3 'binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin'; 50S ribosomal protein L3 225790 rplC 1208119 rplC Coxiella burnetii RSA 493 50S ribosomal protein L3 NP_819282.1 225137 D 227377 CDS NP_819283.2 215918922 1208120 225787..226407 1 NC_002971.3 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 226407 rplD 1208120 rplD Coxiella burnetii RSA 493 50S ribosomal protein L4 NP_819283.2 225787 D 227377 CDS NP_819284.1 29653592 1208121 226404..226691 1 NC_002971.3 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 226691 rplW 1208121 rplW Coxiella burnetii RSA 493 50S ribosomal protein L23 NP_819284.1 226404 D 227377 CDS NP_819285.1 29653593 1208122 226711..227538 1 NC_002971.3 'one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation'; 50S ribosomal protein L2 227538 rplB 1208122 rplB Coxiella burnetii RSA 493 50S ribosomal protein L2 NP_819285.1 226711 D 227377 CDS NP_819286.1 29653594 1208123 227551..227838 1 NC_002971.3 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 227838 rpsS 1208123 rpsS Coxiella burnetii RSA 493 30S ribosomal protein S19 NP_819286.1 227551 D 227377 CDS NP_819287.1 29653595 1208124 227838..228185 1 NC_002971.3 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 228185 rplV 1208124 rplV Coxiella burnetii RSA 493 50S ribosomal protein L22 NP_819287.1 227838 D 227377 CDS NP_819288.1 29653596 1208125 228185..228868 1 NC_002971.3 30S ribosomal protein S3 228868 rpsC 1208125 rpsC Coxiella burnetii RSA 493 30S ribosomal protein S3 NP_819288.1 228185 D 227377 CDS NP_819289.1 29653597 1208126 228880..229293 1 NC_002971.3 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 229293 rplP 1208126 rplP Coxiella burnetii RSA 493 50S ribosomal protein L16 NP_819289.1 228880 D 227377 CDS NP_819290.1 29653598 1208127 229294..229491 1 NC_002971.3 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 229491 rpmC 1208127 rpmC Coxiella burnetii RSA 493 50S ribosomal protein L29 NP_819290.1 229294 D 227377 CDS NP_819291.2 215918923 1208128 229502..229753 1 NC_002971.3 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 229753 rpsQ 1208128 rpsQ Coxiella burnetii RSA 493 30S ribosomal protein S17 NP_819291.2 229502 D 227377 CDS NP_819292.1 29653600 1208129 229764..230132 1 NC_002971.3 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 230132 rplN 1208129 rplN Coxiella burnetii RSA 493 50S ribosomal protein L14 NP_819292.1 229764 D 227377 CDS NP_819293.1 29653601 1208130 230144..230467 1 NC_002971.3 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 230467 rplX 1208130 rplX Coxiella burnetii RSA 493 50S ribosomal protein L24 NP_819293.1 230144 D 227377 CDS NP_819294.1 29653602 1208131 230584..231132 1 NC_002971.3 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 231132 rplE 1208131 rplE Coxiella burnetii RSA 493 50S ribosomal protein L5 NP_819294.1 230584 D 227377 CDS NP_819295.1 29653603 1208132 231137..231436 1 NC_002971.3 30S ribosomal protein S14 231436 rpsN 1208132 rpsN Coxiella burnetii RSA 493 30S ribosomal protein S14 NP_819295.1 231137 D 227377 CDS NP_819296.2 215918924 1208133 231430..231831 1 NC_002971.3 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 231831 rpsH 1208133 rpsH Coxiella burnetii RSA 493 30S ribosomal protein S8 NP_819296.2 231430 D 227377 CDS NP_819297.1 29653605 1208134 231869..232405 1 NC_002971.3 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 232405 rplF 1208134 rplF Coxiella burnetii RSA 493 50S ribosomal protein L6 NP_819297.1 231869 D 227377 CDS NP_819298.1 29653606 1208135 232405..232758 1 NC_002971.3 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 232758 rplR 1208135 rplR Coxiella burnetii RSA 493 50S ribosomal protein L18 NP_819298.1 232405 D 227377 CDS NP_819299.1 29653607 1208136 232770..233276 1 NC_002971.3 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 233276 rpsE 1208136 rpsE Coxiella burnetii RSA 493 30S ribosomal protein S5 NP_819299.1 232770 D 227377 CDS NP_819300.1 29653608 1208137 233280..233471 1 NC_002971.3 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 233471 rpmD 1208137 rpmD Coxiella burnetii RSA 493 50S ribosomal protein L30 NP_819300.1 233280 D 227377 CDS NP_819301.1 29653609 1208138 233474..233905 1 NC_002971.3 late assembly protein; 50S ribosomal protein L15 233905 rplO 1208138 rplO Coxiella burnetii RSA 493 50S ribosomal protein L15 NP_819301.1 233474 D 227377 CDS NP_819302.1 29653610 1208139 233923..235251 1 NC_002971.3 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 235251 secY 1208139 secY Coxiella burnetii RSA 493 preprotein translocase subunit SecY NP_819302.1 233923 D 227377 CDS YP_338278.1 77358717 3704276 235264..235386 1 NC_002971.3 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 235386 rpmJ 3704276 rpmJ Coxiella burnetii RSA 493 50S ribosomal protein L36 YP_338278.1 235264 D 227377 CDS NP_819303.1 29653611 1208140 235526..235621 1 NC_002971.3 hypothetical protein 235621 1208140 CBU_0259 Coxiella burnetii RSA 493 hypothetical protein NP_819303.1 235526 D 227377 CDS NP_819304.1 29653612 1208141 235626..235985 1 NC_002971.3 'located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA'; 30S ribosomal protein S13 235985 rpsM 1208141 rpsM Coxiella burnetii RSA 493 30S ribosomal protein S13 NP_819304.1 235626 D 227377 CDS NP_819305.1 29653613 1208142 236013..236384 1 NC_002971.3 'located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3'; 30S ribosomal protein S11 236384 rpsK 1208142 rpsK Coxiella burnetii RSA 493 30S ribosomal protein S11 NP_819305.1 236013 D 227377 CDS NP_819306.1 29653614 1208143 236397..237017 1 NC_002971.3 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 237017 rpsD 1208143 rpsD Coxiella burnetii RSA 493 30S ribosomal protein S4 NP_819306.1 236397 D 227377 CDS NP_819307.1 29653615 1208144 237030..238013 1 NC_002971.3 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 238013 rpoA 1208144 rpoA Coxiella burnetii RSA 493 DNA-directed RNA polymerase subunit alpha NP_819307.1 237030 D 227377 CDS NP_819308.1 29653616 1208145 238025..238405 1 NC_002971.3 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 238405 rplQ 1208145 rplQ Coxiella burnetii RSA 493 50S ribosomal protein L17 NP_819308.1 238025 D 227377 CDS NP_819309.1 29653617 1208146 238408..239634 1 NC_002971.3 glucose/galactose transporter 239634 1208146 CBU_0265 Coxiella burnetii RSA 493 glucose/galactose transporter NP_819309.1 238408 D 227377 CDS NP_819314.1 29653622 1208151 241159..242379 1 NC_002971.3 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase 242379 1208151 CBU_0270 Coxiella burnetii RSA 493 trans-2-enoyl-CoA reductase NP_819314.1 241159 D 227377 CDS NP_819315.1 29653623 1208152 complement(242391..242867) 1 NC_002971.3 single-stranded DNA-binding protein 242867 ssb 1208152 ssb Coxiella burnetii RSA 493 single-stranded DNA-binding protein NP_819315.1 242391 R 227377 CDS NP_819316.1 29653624 1208153 complement(242917..244293) 1 NC_002971.3 MFS superfamily transporter 244293 1208153 CBU_0272 Coxiella burnetii RSA 493 MFS superfamily transporter NP_819316.1 242917 R 227377 CDS NP_819317.1 29653625 1208154 complement(244378..245124) 1 NC_002971.3 hypothetical protein 245124 1208154 CBU_0273 Coxiella burnetii RSA 493 hypothetical protein NP_819317.1 244378 R 227377 CDS NP_819318.1 29653626 1208155 245376..248240 1 NC_002971.3 excinuclease ABC subunit A 248240 uvrA 1208155 uvrA Coxiella burnetii RSA 493 excinuclease ABC subunit A NP_819318.1 245376 D 227377 CDS YP_002332955.1 215918925 7065954 complement(248322..248486) 1 NC_002971.3 hypothetical protein 248486 7065954 CBU_0274a Coxiella burnetii RSA 493 hypothetical protein YP_002332955.1 248322 R 227377 CDS NP_819319.1 29653627 1208156 248550..249635 1 NC_002971.3 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 249635 hemE 1208156 hemE Coxiella burnetii RSA 493 uroporphyrinogen decarboxylase NP_819319.1 248550 D 227377 CDS NP_819320.2 215918926 1208157 249676..250755 1 NC_002971.3 rubredoxin-NAD(+) reductase 250755 1208157 CBU_0276 Coxiella burnetii RSA 493 rubredoxin-NAD(+) reductase NP_819320.2 249676 D 227377 CDS NP_819321.1 29653629 1208158 complement(250808..250960) 1 NC_002971.3 hypothetical protein 250960 1208158 CBU_0277 Coxiella burnetii RSA 493 hypothetical protein NP_819321.1 250808 R 227377 CDS NP_819322.1 29653630 1208159 251008..251601 1 NC_002971.3 multiple antibiotic resistance protein MarC 251601 1208159 CBU_0278 Coxiella burnetii RSA 493 multiple antibiotic resistance protein MarC NP_819322.1 251008 D 227377 CDS NP_819323.1 29653631 1208160 complement(251625..252452) 1 NC_002971.3 amidinotransferase 252452 1208160 CBU_0279 Coxiella burnetii RSA 493 amidinotransferase NP_819323.1 251625 R 227377 CDS NP_819324.2 215918927 1208161 252514..253632 1 NC_002971.3 DNA polymerase IV 253632 dinP 1208161 dinP Coxiella burnetii RSA 493 DNA polymerase IV NP_819324.2 252514 D 227377 CDS YP_008992029.1 570699738 1208162 253703..254248 1 NC_002971.3 hypothetical protein 254248 1208162 CBU_0282a Coxiella burnetii RSA 493 hypothetical protein YP_008992029.1 253703 D 227377 CDS NP_819327.1 29653635 1208164 254719..254892 1 NC_002971.3 hypothetical protein 254892 1208164 CBU_0283 Coxiella burnetii RSA 493 hypothetical protein NP_819327.1 254719 D 227377 CDS NP_819328.1 29653636 1208165 254880..255107 1 NC_002971.3 prophage protein gp49 255107 1208165 CBU_0284 Coxiella burnetii RSA 493 prophage protein gp49 NP_819328.1 254880 D 227377 CDS NP_819329.1 29653637 1208166 255111..255431 1 NC_002971.3 hypothetical protein 255431 1208166 CBU_0285 Coxiella burnetii RSA 493 hypothetical protein NP_819329.1 255111 D 227377 CDS NP_819330.1 29653638 1208168 255663..256982 1 NC_002971.3 poly(A) polymerase 256982 pcnB 1208168 pcnB Coxiella burnetii RSA 493 poly(A) polymerase NP_819330.1 255663 D 227377 CDS NP_819331.1 29653639 1208169 256979..257539 1 NC_002971.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 257539 folK-2 1208169 folK-2 Coxiella burnetii RSA 493 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_819331.1 256979 D 227377 CDS NP_819332.1 29653640 1208170 257536..258015 1 NC_002971.3 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 258015 coaD 1208170 coaD Coxiella burnetii RSA 493 phosphopantetheine adenylyltransferase NP_819332.1 257536 D 227377 CDS NP_819333.1 29653641 1208171 258030..258275 1 NC_002971.3 ferredoxin 258275 1208171 CBU_0289 Coxiella burnetii RSA 493 ferredoxin NP_819333.1 258030 D 227377 CDS NP_819334.1 29653642 1208172 complement(258289..258501) 1 NC_002971.3 50S ribosomal protein L33 258501 rpmG 1208172 rpmG Coxiella burnetii RSA 493 50S ribosomal protein L33 NP_819334.1 258289 R 227377 CDS NP_819335.1 29653643 1208173 complement(258512..258751) 1 NC_002971.3 required for 70S ribosome assembly; 50S ribosomal protein L28 258751 rpmB 1208173 rpmB Coxiella burnetii RSA 493 50S ribosomal protein L28 NP_819335.1 258512 R 227377 CDS YP_002332956.1 215918928 7065971 complement(259529..259885) 1 NC_002971.3 hypothetical protein 259885 7065971 CBU_0291b Coxiella burnetii RSA 493 hypothetical protein YP_002332956.1 259529 R 227377 CDS NP_819336.2 215918929 1208175 259899..260384 1 NC_002971.3 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 260384 dut 1208175 dut Coxiella burnetii RSA 493 deoxyuridine 5'-triphosphate nucleotidohydrolase NP_819336.2 259899 D 227377 CDS NP_819337.2 215918930 1208176 260362..261777 1 NC_002971.3 phosphomannomutase; phosphoglucomutase 261777 1208176 CBU_0294 Coxiella burnetii RSA 493 phosphoglucomutase NP_819337.2 260362 D 227377 CDS NP_819338.1 29653646 1208177 complement(261774..263243) 1 NC_002971.3 hypothetical protein 263243 1208177 CBU_0295 Coxiella burnetii RSA 493 hypothetical protein NP_819338.1 261774 R 227377 CDS NP_819339.2 215918931 1208178 complement(263240..263887) 1 NC_002971.3 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 263887 pyrE 1208178 pyrE Coxiella burnetii RSA 493 orotate phosphoribosyltransferase NP_819339.2 263240 R 227377 CDS NP_819340.1 29653648 1208179 263915..264694 1 NC_002971.3 exodeoxyribonuclease III 264694 xth 1208179 xth Coxiella burnetii RSA 493 exodeoxyribonuclease III NP_819340.1 263915 D 227377 CDS NP_819341.1 29653649 1208180 complement(264950..265792) 1 NC_002971.3 glutamate racemase 265792 murI 1208180 murI Coxiella burnetii RSA 493 glutamate racemase NP_819341.1 264950 R 227377 CDS NP_819342.2 215918932 1208181 complement(265792..266511) 1 NC_002971.3 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 266511 rph 1208181 rph Coxiella burnetii RSA 493 ribonuclease PH NP_819342.2 265792 R 227377 CDS NP_819343.1 29653651 1208182 266649..267512 1 NC_002971.3 hypothetical protein 267512 1208182 CBU_0300 Coxiella burnetii RSA 493 hypothetical protein NP_819343.1 266649 D 227377 CDS NP_819344.1 29653652 1208183 267505..268125 1 NC_002971.3 'Essential for recycling GMP and indirectly, cGMP'; guanylate kinase 268125 gmk 1208183 gmk Coxiella burnetii RSA 493 guanylate kinase NP_819344.1 267505 D 227377 CDS NP_819345.1 29653653 1208184 268203..268496 1 NC_002971.3 DNA-directed RNA polymerase subunit omega 268496 rpoZ 1208184 rpoZ Coxiella burnetii RSA 493 DNA-directed RNA polymerase subunit omega NP_819345.1 268203 D 227377 CDS NP_819346.1 29653654 1208185 268550..270673 1 NC_002971.3 guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; GTP pyrophosphokinase 270673 spoT 1208185 spoT Coxiella burnetii RSA 493 GTP pyrophosphokinase NP_819346.1 268550 D 227377 CDS NP_819347.2 215918933 1208186 270701..271147 1 NC_002971.3 endoribonuclease L-PSP 271147 1208186 CBU_0304 Coxiella burnetii RSA 493 endoribonuclease L-PSP NP_819347.2 270701 D 227377 CDS NP_819348.1 29653656 1208187 271154..273268 1 NC_002971.3 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 273268 recG 1208187 recG Coxiella burnetii RSA 493 ATP-dependent DNA helicase RecG NP_819348.1 271154 D 227377 CDS NP_819349.1 29653657 1208188 273549..273668 1 NC_002971.3 hypothetical protein 273668 1208188 CBU_0306 Coxiella burnetii RSA 493 hypothetical protein NP_819349.1 273549 D 227377 CDS NP_819350.1 29653658 1208189 273668..274363 1 NC_002971.3 OmpA-like transmembrane domain-containing protein 274363 1208189 CBU_0307 Coxiella burnetii RSA 493 OmpA-like transmembrane domain-containing protein NP_819350.1 273668 D 227377 CDS YP_002332957.1 215918935 7065905 complement(274447..274692) 1 NC_002971.3 hypothetical protein 274692 7065905 CBU_0307a Coxiella burnetii RSA 493 hypothetical protein YP_002332957.1 274447 R 227377 CDS NP_819352.2 215918934 1208191 274678..276648 1 NC_002971.3 molecular chaperone; heat shock protein 90 276648 htpG 1208191 htpG Coxiella burnetii RSA 493 heat shock protein 90 NP_819352.2 274678 D 227377 CDS NP_819354.2 215918936 1208193 276910..277668 1 NC_002971.3 hypothetical protein 277668 1208193 CBU_0311 Coxiella burnetii RSA 493 hypothetical protein NP_819354.2 276910 D 227377 CDS NP_819355.1 29653663 1208194 complement(277827..278678) 1 NC_002971.3 'catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate'; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 278678 folD 1208194 folD Coxiella burnetii RSA 493 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_819355.1 277827 R 227377 CDS YP_002332958.1 215918937 7065935 278988..279107 1 NC_002971.3 hypothetical protein 279107 7065935 CBU_0312a Coxiella burnetii RSA 493 hypothetical protein YP_002332958.1 278988 D 227377 CDS NP_819356.2 215918938 1208195 complement(279376..280875) 1 NC_002971.3 Slt family transglycosylase 280875 1208195 CBU_0313 Coxiella burnetii RSA 493 Slt family transglycosylase NP_819356.2 279376 R 227377 CDS NP_819357.1 29653665 1208196 complement(281012..281785) 1 NC_002971.3 hydroxyacylglutathione hydrolase 281785 1208196 CBU_0314 Coxiella burnetii RSA 493 hydroxyacylglutathione hydrolase NP_819357.1 281012 R 227377 CDS NP_819358.1 29653666 1208197 281850..282581 1 NC_002971.3 methyltransferase 282581 1208197 CBU_0315 Coxiella burnetii RSA 493 methyltransferase NP_819358.1 281850 D 227377 CDS NP_819359.1 29653667 1208198 282596..283060 1 NC_002971.3 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 283060 rnhA 1208198 rnhA Coxiella burnetii RSA 493 ribonuclease H NP_819359.1 282596 D 227377 CDS YP_002332959.1 215918939 7065894 complement(283119..283271) 1 NC_002971.3 hypothetical protein 283271 7065894 CBU_0316a Coxiella burnetii RSA 493 hypothetical protein YP_002332959.1 283119 R 227377 CDS NP_819360.2 215918940 1208199 283478..284188 1 NC_002971.3 DNA polymerase III subunit epsilon 284188 dnaQ 1208199 dnaQ Coxiella burnetii RSA 493 DNA polymerase III subunit epsilon NP_819360.2 283478 D 227377 CDS NP_819361.1 29653669 1208200 complement(284182..284826) 1 NC_002971.3 ErfK/YbiS/YcfS/YnhG family protein 284826 enhA.2 1208200 enhA.2 Coxiella burnetii RSA 493 ErfK/YbiS/YcfS/YnhG family protein NP_819361.1 284182 R 227377 CDS NP_819362.1 29653670 1208201 284817..284933 1 NC_002971.3 hypothetical protein 284933 1208201 CBU_0319 Coxiella burnetii RSA 493 hypothetical protein NP_819362.1 284817 D 227377 CDS NP_819363.1 29653671 1208203 complement(287935..288708) 1 NC_002971.3 IcmH 288708 icmH 1208203 icmH Coxiella burnetii RSA 493 IcmH NP_819363.1 287935 R 227377 CDS NP_819364.1 29653672 1208204 288902..289774 1 NC_002971.3 hypothetical protein 289774 1208204 CBU_0322 Coxiella burnetii RSA 493 hypothetical protein NP_819364.1 288902 D 227377 CDS NP_819365.1 29653673 1208205 289771..290022 1 NC_002971.3 acyl carrier protein 290022 1208205 CBU_0323 Coxiella burnetii RSA 493 acyl carrier protein NP_819365.1 289771 D 227377 CDS NP_819366.2 215918941 1208206 290036..291682 1 NC_002971.3 acyl-CoA synthetase 291682 1208206 CBU_0324 Coxiella burnetii RSA 493 acyl-CoA synthetase NP_819366.2 290036 D 227377 CDS NP_819368.2 215918942 1208208 complement(291944..293257) 1 NC_002971.3 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 293257 purD 1208208 purD Coxiella burnetii RSA 493 phosphoribosylamine--glycine ligase NP_819368.2 291944 R 227377 CDS NP_819372.2 215918943 1208212 296556..298220 1 NC_002971.3 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 298220 thiC 1208212 thiC Coxiella burnetii RSA 493 thiamine biosynthesis protein ThiC NP_819372.2 296556 D 227377 CDS NP_819373.2 215918944 1208213 298220..299242 1 NC_002971.3 glycine oxidase ThiO 299242 1208213 CBU_0331 Coxiella burnetii RSA 493 glycine oxidase ThiO NP_819373.2 298220 D 227377 CDS NP_819374.1 29653682 1208214 299239..299442 1 NC_002971.3 sulfur carrier protein ThiS 299442 thiS 1208214 thiS Coxiella burnetii RSA 493 sulfur carrier protein ThiS NP_819374.1 299239 D 227377 CDS NP_819375.1 29653683 1208215 299444..300223 1 NC_002971.3 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 300223 thiG 1208215 thiG Coxiella burnetii RSA 493 thiazole synthase NP_819375.1 299444 D 227377 CDS NP_819376.1 29653684 1208216 300220..301659 1 NC_002971.3 thiamine-phosphate pyrophosphorylase/thiamine-phosphate pyrophosphorylase 301659 thiDE 1208216 thiDE Coxiella burnetii RSA 493 thiamine-phosphate pyrophosphorylase/thiamine-phosphate pyrophosphorylase NP_819376.1 300220 D 227377 CDS NP_819377.1 29653685 1208217 301737..302402 1 NC_002971.3 acid phosphatase 302402 1208217 CBU_0335 Coxiella burnetii RSA 493 acid phosphatase NP_819377.1 301737 D 227377 CDS NP_819378.2 215918945 1208218 complement(302428..304011) 1 NC_002971.3 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 304011 purH 1208218 purH Coxiella burnetii RSA 493 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_819378.2 302428 R 227377 CDS NP_819379.1 29653687 1208219 complement(303992..304303) 1 NC_002971.3 Fis family transcriptional regulator 304303 fis 1208219 fis Coxiella burnetii RSA 493 Fis family transcriptional regulator NP_819379.1 303992 R 227377 CDS NP_819380.2 215918946 1208220 304467..307172 1 NC_002971.3 aminopeptidase 307172 pepN 1208220 pepN Coxiella burnetii RSA 493 aminopeptidase NP_819380.2 304467 D 227377 CDS NP_819381.1 29653689 1208221 complement(307194..307955) 1 NC_002971.3 hypothetical protein 307955 1208221 CBU_0339 Coxiella burnetii RSA 493 hypothetical protein NP_819381.1 307194 R 227377 CDS NP_819382.1 29653690 1208222 308186..309124 1 NC_002971.3 hypothetical protein 309124 1208222 CBU_0340 Coxiella burnetii RSA 493 hypothetical protein NP_819382.1 308186 D 227377 CDS NP_819383.2 215918947 1208223 complement(309166..310164) 1 NC_002971.3 6-phosphofructokinase 310164 pfkA 1208223 pfkA Coxiella burnetii RSA 493 6-phosphofructokinase NP_819383.2 309166 R 227377 CDS NP_819384.1 29653692 1208224 310148..310264 1 NC_002971.3 hypothetical protein 310264 1208224 CBU_0342 Coxiella burnetii RSA 493 hypothetical protein NP_819384.1 310148 D 227377 CDS NP_819385.1 29653693 1208225 310601..311482 1 NC_002971.3 hypothetical protein 311482 1208225 CBU_0343 Coxiella burnetii RSA 493 hypothetical protein NP_819385.1 310601 D 227377 CDS NP_819387.1 29653695 1208228 complement(313482..314966) 1 NC_002971.3 xylulose kinase 314966 xylB 1208228 xylB Coxiella burnetii RSA 493 xylulose kinase NP_819387.1 313482 R 227377 CDS NP_819388.2 215918948 1208229 complement(314971..316362) 1 NC_002971.3 D-xylose-proton symporter 316362 1208229 CBU_0347 Coxiella burnetii RSA 493 D-xylose-proton symporter NP_819388.2 314971 R 227377 CDS NP_819390.1 29653698 1208231 complement(316403..317086) 1 NC_002971.3 phosphoglycolate phosphatase 317086 gph 1208231 gph Coxiella burnetii RSA 493 phosphoglycolate phosphatase NP_819390.1 316403 R 227377 CDS NP_819391.1 29653699 1208232 complement(317079..317783) 1 NC_002971.3 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 317783 ubiG 1208232 ubiG Coxiella burnetii RSA 493 3-demethylubiquinone-9 3-methyltransferase NP_819391.1 317079 R 227377 CDS NP_819392.1 29653700 1208233 complement(317770..318123) 1 NC_002971.3 Hpt domain-containing protein 318123 1208233 CBU_0351 Coxiella burnetii RSA 493 Hpt domain-containing protein NP_819392.1 317770 R 227377 CDS NP_819393.1 29653701 1208234 complement(318169..319062) 1 NC_002971.3 cation efflux system protein CzcD 319062 czcD.1 1208234 czcD.1 Coxiella burnetii RSA 493 cation efflux system protein CzcD NP_819393.1 318169 R 227377 CDS NP_819394.1 29653702 1208235 complement(319199..320215) 1 NC_002971.3 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 320215 1208235 CBU_0353 Coxiella burnetii RSA 493 periplasmic protease NP_819394.1 319199 R 227377 CDS NP_819395.2 215918949 1208236 320424..322001 1 NC_002971.3 amino acid permease 322001 1208236 CBU_0354 Coxiella burnetii RSA 493 amino acid permease NP_819395.2 320424 D 227377 CDS NP_819398.1 29653706 1208239 324094..324321 1 NC_002971.3 hypothetical protein 324321 1208239 CBU_0357 Coxiella burnetii RSA 493 hypothetical protein NP_819398.1 324094 D 227377 CDS NP_819403.1 29653711 1208244 complement(327068..328273) 1 NC_002971.3 amidohydrolase 328273 1208244 CBU_0362 Coxiella burnetii RSA 493 amidohydrolase NP_819403.1 327068 R 227377 CDS NP_819404.2 215918950 1208246 complement(329355..330686) 1 NC_002971.3 phosphate transporter 330686 1208246 CBU_0364 Coxiella burnetii RSA 493 phosphate transporter NP_819404.2 329355 R 227377 CDS NP_819405.1 29653713 1208247 330772..330864 1 NC_002971.3 hypothetical protein 330864 1208247 CBU_0365 Coxiella burnetii RSA 493 hypothetical protein NP_819405.1 330772 D 227377 CDS NP_819406.1 29653714 1208248 complement(330861..331619) 1 NC_002971.3 hypothetical protein 331619 phoR 1208248 phoR Coxiella burnetii RSA 493 hypothetical protein NP_819406.1 330861 R 227377 CDS NP_819407.1 29653715 1208249 complement(331600..332346) 1 NC_002971.3 PhoB family transcriptional regulator 332346 phoB 1208249 phoB Coxiella burnetii RSA 493 PhoB family transcriptional regulator NP_819407.1 331600 R 227377 CDS NP_819408.2 215918951 1208250 332398..333582 1 NC_002971.3 glucose/sorbosone dehydrogenase 333582 1208250 CBU_0368 Coxiella burnetii RSA 493 glucose/sorbosone dehydrogenase NP_819408.2 332398 D 227377 CDS NP_819409.1 29653717 1208251 complement(333585..333689) 1 NC_002971.3 hypothetical protein 333689 1208251 CBU_0369 Coxiella burnetii RSA 493 hypothetical protein NP_819409.1 333585 R 227377 CDS NP_819410.1 29653718 1208252 complement(333753..333980) 1 NC_002971.3 surface antigen 333980 1208252 CBU_0370 Coxiella burnetii RSA 493 surface antigen NP_819410.1 333753 R 227377 CDS NP_819411.1 29653719 1208253 complement(334052..335245) 1 NC_002971.3 multidrug resistance transporter, Bcr family 335245 1208253 CBU_0371 Coxiella burnetii RSA 493 multidrug resistance transporter, Bcr family NP_819411.1 334052 R 227377 CDS NP_819412.1 29653720 1208254 complement(335348..336712) 1 NC_002971.3 Fic family protein 336712 1208254 CBU_0372 Coxiella burnetii RSA 493 Fic family protein NP_819412.1 335348 R 227377 CDS NP_819413.1 29653721 1208255 complement(336859..337383) 1 NC_002971.3 acyl dehydratase MaoC 337383 1208255 CBU_0373 Coxiella burnetii RSA 493 acyl dehydratase MaoC NP_819413.1 336859 R 227377 CDS NP_819416.1 29653724 1208259 339869..340090 1 NC_002971.3 hypothetical protein 340090 1208259 CBU_0377 Coxiella burnetii RSA 493 hypothetical protein NP_819416.1 339869 D 227377 CDS NP_819417.1 29653725 1208260 340247..340669 1 NC_002971.3 lipoprotein 340669 1208260 CBU_0378 Coxiella burnetii RSA 493 lipoprotein NP_819417.1 340247 D 227377 CDS NP_819418.1 29653726 1208261 complement(340684..341457) 1 NC_002971.3 anhydro-N-acetylmuramyl-tripeptide amidase 341457 ampD 1208261 ampD Coxiella burnetii RSA 493 anhydro-N-acetylmuramyl-tripeptide amidase NP_819418.1 340684 R 227377 CDS NP_819419.1 29653727 1208262 complement(341474..341599) 1 NC_002971.3 hypothetical protein 341599 1208262 CBU_0380 Coxiella burnetii RSA 493 hypothetical protein NP_819419.1 341474 R 227377 CDS NP_819420.2 215918952 1208263 341677..342240 1 NC_002971.3 glutamate-rich protein 342240 grpB 1208263 grpB Coxiella burnetii RSA 493 glutamate-rich protein NP_819420.2 341677 D 227377 CDS NP_819421.1 29653729 1208265 complement(343024..344022) 1 NC_002971.3 polyprenyl synthetase 344022 ispB 1208265 ispB Coxiella burnetii RSA 493 polyprenyl synthetase NP_819421.1 343024 R 227377 CDS NP_819422.2 215918953 1208266 344088..344726 1 NC_002971.3 DNA-3-methyladenine glycosylase I 344726 tag 1208266 tag Coxiella burnetii RSA 493 DNA-3-methyladenine glycosylase I NP_819422.2 344088 D 227377 CDS NP_819423.2 215918954 1208267 345003..346097 1 NC_002971.3 IS1111A transposase 346097 1208267 CBU_0384 Coxiella burnetii RSA 493 IS1111A transposase NP_819423.2 345003 D 227377 CDS YP_002332960.1 215918955 7065863 complement(346094..346366) 1 NC_002971.3 hypothetical protein 346366 7065863 CBU_0384a Coxiella burnetii RSA 493 hypothetical protein YP_002332960.1 346094 R 227377 CDS YP_002332961.1 215918956 7065938 346413..346598 1 NC_002971.3 hypothetical protein 346598 7065938 CBU_0384b Coxiella burnetii RSA 493 hypothetical protein YP_002332961.1 346413 D 227377 CDS NP_819424.2 215918957 1208268 346685..347038 1 NC_002971.3 50S ribosomal protein L21 347038 rplU 1208268 rplU Coxiella burnetii RSA 493 50S ribosomal protein L21 NP_819424.2 346685 D 227377 CDS NP_819425.1 29653733 1208269 347028..347300 1 NC_002971.3 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 347300 rpmA 1208269 rpmA Coxiella burnetii RSA 493 50S ribosomal protein L27 NP_819425.1 347028 D 227377 CDS NP_819426.1 29653734 1208270 347465..348484 1 NC_002971.3 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 348484 obgE 1208270 obgE Coxiella burnetii RSA 493 GTPase ObgE NP_819426.1 347465 D 227377 CDS NP_819427.1 29653735 1208271 348584..352762 1 NC_002971.3 hypothetical protein 352762 1208271 CBU_0388 Coxiella burnetii RSA 493 hypothetical protein NP_819427.1 348584 D 227377 CDS NP_819428.1 29653736 1208272 complement(352768..353040) 1 NC_002971.3 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 353040 rpsT 1208272 rpsT Coxiella burnetii RSA 493 30S ribosomal protein S20 NP_819428.1 352768 R 227377 CDS NP_819429.1 29653737 1208273 353284..354831 1 NC_002971.3 virulence factor 354831 mviN 1208273 mviN Coxiella burnetii RSA 493 virulence factor NP_819429.1 353284 D 227377 CDS NP_819430.2 215918958 1208274 354828..355865 1 NC_002971.3 riboflavin kinase; FMN adenylyltransferase 355865 ribF 1208274 ribF Coxiella burnetii RSA 493 FMN adenylyltransferase NP_819430.2 354828 D 227377 CDS NP_819433.1 29653741 1208277 complement(357828..357947) 1 NC_002971.3 hypothetical protein 357947 1208277 CBU_0394 Coxiella burnetii RSA 493 hypothetical protein NP_819433.1 357828 R 227377 CDS NP_819434.1 29653742 1208278 358040..358726 1 NC_002971.3 lipoprotein 358726 1208278 CBU_0395 Coxiella burnetii RSA 493 lipoprotein NP_819434.1 358040 D 227377 CDS NP_819435.1 29653743 1208279 358839..361649 1 NC_002971.3 'IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme'; isoleucyl-tRNA synthetase 361649 ileS 1208279 ileS Coxiella burnetii RSA 493 isoleucyl-tRNA synthetase NP_819435.1 358839 D 227377 CDS NP_819436.2 215918959 1208280 361652..362149 1 NC_002971.3 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 362149 lspA 1208280 lspA Coxiella burnetii RSA 493 lipoprotein signal peptidase NP_819436.2 361652 D 227377 CDS NP_819437.1 29653745 1208281 362161..362709 1 NC_002971.3 hypothetical protein 362709 1208281 CBU_0398 Coxiella burnetii RSA 493 hypothetical protein NP_819437.1 362161 D 227377 CDS NP_819439.1 29653747 1208283 362731..363210 1 NC_002971.3 hypothetical protein 363210 1208283 CBU_0400 Coxiella burnetii RSA 493 hypothetical protein NP_819439.1 362731 D 227377 CDS YP_002332962.1 215918960 7065945 363207..363356 1 NC_002971.3 hypothetical protein 363356 7065945 CBU_0400a Coxiella burnetii RSA 493 hypothetical protein YP_002332962.1 363207 D 227377 CDS NP_819441.1 29653749 1208285 363394..363501 1 NC_002971.3 acetyltransferase 363501 1208285 CBU_0402 Coxiella burnetii RSA 493 acetyltransferase NP_819441.1 363394 D 227377 CDS NP_819442.1 29653750 1208286 363498..363635 1 NC_002971.3 acetyltransferase 363635 1208286 CBU_0403 Coxiella burnetii RSA 493 acetyltransferase NP_819442.1 363498 D 227377 CDS NP_819446.1 29653754 1208290 complement(365200..365301) 1 NC_002971.3 hypothetical protein 365301 1208290 CBU_0407 Coxiella burnetii RSA 493 hypothetical protein NP_819446.1 365200 R 227377 CDS NP_819447.1 29653755 1208292 complement(365803..365958) 1 NC_002971.3 hypothetical protein 365958 1208292 CBU_0409 Coxiella burnetii RSA 493 hypothetical protein NP_819447.1 365803 R 227377 CDS NP_819448.1 29653756 1208293 complement(366234..367970) 1 NC_002971.3 hypothetical protein 367970 1208293 CBU_0410 Coxiella burnetii RSA 493 hypothetical protein NP_819448.1 366234 R 227377 CDS NP_819449.1 29653757 1208294 368162..368257 1 NC_002971.3 hypothetical protein 368257 1208294 CBU_0411 Coxiella burnetii RSA 493 hypothetical protein NP_819449.1 368162 D 227377 CDS NP_819450.1 29653758 1208295 complement(368385..368795) 1 NC_002971.3 type IV pilin 368795 pilE 1208295 pilE Coxiella burnetii RSA 493 type IV pilin NP_819450.1 368385 R 227377 CDS NP_819453.2 215918961 1208299 complement(370484..370990) 1 NC_002971.3 guanine deaminase 370990 1208299 CBU_0415 Coxiella burnetii RSA 493 guanine deaminase NP_819453.2 370484 R 227377 CDS NP_819454.2 215918962 1208300 371308..371490 1 NC_002971.3 hypothetical protein 371490 1208300 CBU_0416 Coxiella burnetii RSA 493 hypothetical protein NP_819454.2 371308 D 227377 CDS NP_819455.2 215918963 1208301 371542..371679 1 NC_002971.3 hypothetical protein 371679 1208301 CBU_0417 Coxiella burnetii RSA 493 hypothetical protein NP_819455.2 371542 D 227377 CDS NP_819456.1 29653764 1208302 complement(371728..372573) 1 NC_002971.3 branched-chain amino acid aminotransferase 372573 1208302 CBU_0418 Coxiella burnetii RSA 493 branched-chain amino acid aminotransferase NP_819456.1 371728 R 227377 CDS NP_819457.1 29653765 1208303 complement(372676..373506) 1 NC_002971.3 polysaccharide deacetylase 373506 1208303 CBU_0419 Coxiella burnetii RSA 493 polysaccharide deacetylase NP_819457.1 372676 R 227377 CDS NP_819460.1 29653768 1208306 complement(375346..375681) 1 NC_002971.3 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 375681 panD 1208306 panD Coxiella burnetii RSA 493 aspartate alpha-decarboxylase NP_819460.1 375346 R 227377 CDS NP_819461.1 29653769 1208307 complement(375675..376448) 1 NC_002971.3 pantoate--beta-alanine ligase 376448 panC 1208307 panC Coxiella burnetii RSA 493 pantoate--beta-alanine ligase NP_819461.1 375675 R 227377 CDS NP_819462.1 29653770 1208308 complement(376459..377259) 1 NC_002971.3 'catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate'; 3-methyl-2-oxobutanoate hydroxymethyltransferase 377259 panB 1208308 panB Coxiella burnetii RSA 493 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_819462.1 376459 R 227377 CDS NP_819463.1 29653771 1208309 complement(377351..378718) 1 NC_002971.3 hypothetical protein 378718 1208309 CBU_0425 Coxiella burnetii RSA 493 hypothetical protein NP_819463.1 377351 R 227377 CDS NP_819464.2 215918965 1208310 complement(378965..380905) 1 NC_002971.3 amino acid permease 380905 1208310 CBU_0426 Coxiella burnetii RSA 493 amino acid permease NP_819464.2 378965 R 227377 CDS YP_002332963.1 215918964 7065884 380654..380740 1 NC_002971.3 hypothetical protein 380740 7065884 CBU_0426a Coxiella burnetii RSA 493 hypothetical protein YP_002332963.1 380654 D 227377 CDS YP_008992030.1 570699739 18126241 381213..382082 1 NC_002971.3 peptide chain release factor 1 382082 18126241 CBU_0428a Coxiella burnetii RSA 493 peptide chain release factor 1 YP_008992030.1 381213 D 227377 CDS NP_819466.1 29653774 1208313 382066..382461 1 NC_002971.3 peptidyl-tRNA hydrolase domain-containing protein 382461 1208313 CBU_0429 Coxiella burnetii RSA 493 peptidyl-tRNA hydrolase domain-containing protein NP_819466.1 382066 D 227377 CDS NP_819467.1 29653775 1208314 382593..384089 1 NC_002971.3 'class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1'; lysyl-tRNA synthetase 384089 lysS 1208314 lysS Coxiella burnetii RSA 493 lysyl-tRNA synthetase NP_819467.1 382593 D 227377 CDS NP_819468.1 29653776 1208315 complement(384058..384834) 1 NC_002971.3 glycine cleavage T-protein (aminomethyl transferase) domain protein 384834 1208315 CBU_0431 Coxiella burnetii RSA 493 glycine cleavage T-protein (aminomethyl transferase) domain protein NP_819468.1 384058 R 227377 CDS NP_819469.1 29653777 1208316 384941..386227 1 NC_002971.3 MFS superfamily transporter 386227 1208316 CBU_0432 Coxiella burnetii RSA 493 MFS superfamily transporter NP_819469.1 384941 D 227377 CDS NP_819470.1 29653778 1208317 386294..386815 1 NC_002971.3 transporter, small conductance mechanosensitive ion channel (MscS) family 386815 1208317 CBU_0433 Coxiella burnetii RSA 493 transporter, small conductance mechanosensitive ion channel (MscS) family NP_819470.1 386294 D 227377 CDS NP_819471.1 29653779 1208318 complement(386915..387034) 1 NC_002971.3 hypothetical protein 387034 1208318 CBU_0434 Coxiella burnetii RSA 493 hypothetical protein NP_819471.1 386915 R 227377 CDS YP_002332964.1 215918966 7065942 complement(387133..387351) 1 NC_002971.3 hypothetical protein 387351 7065942 CBU_0434a Coxiella burnetii RSA 493 hypothetical protein YP_002332964.1 387133 R 227377 CDS NP_819473.1 29653781 1208320 complement(387975..388751) 1 NC_002971.3 hypothetical protein 388751 1208320 CBU_0436 Coxiella burnetii RSA 493 hypothetical protein NP_819473.1 387975 R 227377 CDS NP_819476.1 29653784 1208323 389576..389710 1 NC_002971.3 hypothetical protein 389710 1208323 CBU_0439 Coxiella burnetii RSA 493 hypothetical protein NP_819476.1 389576 D 227377 CDS NP_819477.1 29653785 1208324 389688..389885 1 NC_002971.3 hypothetical protein 389885 1208324 CBU_0440 Coxiella burnetii RSA 493 hypothetical protein NP_819477.1 389688 D 227377 CDS NP_819478.1 29653786 1208325 complement(389985..390500) 1 NC_002971.3 methylated-DNA-[protein]-cysteine S-methyltransferase 390500 ogt 1208325 ogt Coxiella burnetii RSA 493 methylated-DNA-[protein]-cysteine S-methyltransferase NP_819478.1 389985 R 227377 CDS NP_819479.1 29653787 1208326 complement(390506..390853) 1 NC_002971.3 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 390853 rplS 1208326 rplS Coxiella burnetii RSA 493 50S ribosomal protein L19 NP_819479.1 390506 R 227377 CDS NP_819480.1 29653788 1208327 complement(390850..391590) 1 NC_002971.3 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 391590 trmD 1208327 trmD Coxiella burnetii RSA 493 tRNA (guanine-N(1)-)-methyltransferase NP_819480.1 390850 R 227377 CDS NP_819481.1 29653789 1208328 complement(391592..392098) 1 NC_002971.3 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 392098 rimM 1208328 rimM Coxiella burnetii RSA 493 16S rRNA-processing protein RimM NP_819481.1 391592 R 227377 CDS NP_819482.2 215918967 1208329 complement(392177..392722) 1 NC_002971.3 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 392722 rpsP 1208329 rpsP Coxiella burnetii RSA 493 30S ribosomal protein S16 NP_819482.2 392177 R 227377 CDS NP_819483.1 29653791 1208330 393037..393747 1 NC_002971.3 hypothetical protein 393747 1208330 CBU_0446 Coxiella burnetii RSA 493 hypothetical protein NP_819483.1 393037 D 227377 CDS NP_819484.1 29653792 1208331 complement(393840..394394) 1 NC_002971.3 ankyrin repeat-containing protein 394394 1208331 CBU_0447 Coxiella burnetii RSA 493 ankyrin repeat-containing protein NP_819484.1 393840 R 227377 CDS NP_819485.1 29653793 1208332 394433..394528 1 NC_002971.3 hypothetical protein 394528 1208332 CBU_0448 Coxiella burnetii RSA 493 hypothetical protein NP_819485.1 394433 D 227377 CDS NP_819486.1 29653794 1208334 complement(395551..396936) 1 NC_002971.3 signal recognition particle subunit FFH/SRP54 396936 ffh 1208334 ffh Coxiella burnetii RSA 493 signal recognition particle subunit FFH/SRP54 NP_819486.1 395551 R 227377 CDS NP_819487.2 215918968 1208335 396962..397510 1 NC_002971.3 cytochrome C assembly protein 397510 1208335 CBU_0451 Coxiella burnetii RSA 493 cytochrome C assembly protein NP_819487.2 396962 D 227377 CDS NP_819488.1 29653796 1208336 397507..398760 1 NC_002971.3 transporter, HlyC/CorC (HCC) family 398760 corB 1208336 corB Coxiella burnetii RSA 493 transporter, HlyC/CorC (HCC) family NP_819488.1 397507 D 227377 CDS NP_819489.2 215918969 1208337 398762..399322 1 NC_002971.3 fimT protein 399322 fimT 1208337 fimT Coxiella burnetii RSA 493 fimT protein NP_819489.2 398762 D 227377 CDS NP_819490.1 29653798 1208338 399357..400052 1 NC_002971.3 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; nucleoside-diphosphate kinase; adenylate kinase 400052 adk 1208338 adk Coxiella burnetii RSA 493 adenylate kinase NP_819490.1 399357 D 227377 CDS NP_819491.1 29653799 1208339 400086..400451 1 NC_002971.3 thioredoxin 400451 1208339 CBU_0455 Coxiella burnetii RSA 493 thioredoxin NP_819491.1 400086 D 227377 CDS NP_819492.1 29653800 1208340 complement(400477..400830) 1 NC_002971.3 DNA-binding protein 400830 1208340 CBU_0456 Coxiella burnetii RSA 493 DNA-binding protein NP_819492.1 400477 R 227377 CDS NP_819493.1 29653801 1208341 complement(400976..401095) 1 NC_002971.3 hypothetical protein 401095 1208341 CBU_0457 Coxiella burnetii RSA 493 hypothetical protein NP_819493.1 400976 R 227377 CDS NP_819494.1 29653802 1208342 401121..401522 1 NC_002971.3 hypothetical protein 401522 1208342 CBU_0458 Coxiella burnetii RSA 493 hypothetical protein NP_819494.1 401121 D 227377 CDS NP_819495.2 215918970 1208343 401501..402721 1 NC_002971.3 transporter, monovalent cation:proton antiporter-2 (CPA2) family 402721 rosB 1208343 rosB Coxiella burnetii RSA 493 transporter, monovalent cation:proton antiporter-2 (CPA2) family NP_819495.2 401501 D 227377 CDS NP_819496.1 29653804 1208344 402797..403573 1 NC_002971.3 beta-lactamase induction protein 403573 ampE 1208344 ampE Coxiella burnetii RSA 493 beta-lactamase induction protein NP_819496.1 402797 D 227377 CDS NP_819497.1 29653805 1208345 403618..406272 1 NC_002971.3 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 406272 aceE 1208345 aceE Coxiella burnetii RSA 493 pyruvate dehydrogenase subunit E1 NP_819497.1 403618 D 227377 CDS NP_819498.1 29653806 1208346 406338..407648 1 NC_002971.3 dihydrolipoyllysine-residue acetyltransferase E2 component of pyruvate dehydrogenase complex 407648 pdhC 1208346 pdhC Coxiella burnetii RSA 493 dihydrolipoyllysine-residue acetyltransferase E2 component of pyruvate dehydrogenase complex NP_819498.1 406338 D 227377 CDS NP_819499.1 29653807 1208347 407661..409085 1 NC_002971.3 dihydrolipoyl dehydrogenase, E3 component of pyruvate dehydrogenases complex 409085 lpdA 1208347 lpdA Coxiella burnetii RSA 493 dihydrolipoyl dehydrogenase, E3 component of pyruvate dehydrogenases complex NP_819499.1 407661 D 227377 CDS NP_819500.1 29653808 1208349 409709..409804 1 NC_002971.3 hypothetical protein 409804 1208349 CBU_0465 Coxiella burnetii RSA 493 hypothetical protein NP_819500.1 409709 D 227377 CDS NP_819502.1 29653810 1208351 410379..411227 1 NC_002971.3 methyltransferase 411227 bioC.1 1208351 bioC.1 Coxiella burnetii RSA 493 methyltransferase NP_819502.1 410379 D 227377 CDS NP_819503.1 29653811 1208352 complement(411228..411476) 1 NC_002971.3 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 411476 xseB 1208352 xseB Coxiella burnetii RSA 493 exodeoxyribonuclease VII small subunit NP_819503.1 411228 R 227377 CDS NP_819504.1 29653812 1208353 complement(411489..411692) 1 NC_002971.3 hypothetical protein 411692 1208353 CBU_0469 Coxiella burnetii RSA 493 hypothetical protein NP_819504.1 411489 R 227377 CDS NP_819505.1 29653813 1208354 complement(411739..412395) 1 NC_002971.3 phosphoribosyl transferase 412395 1208354 CBU_0470 Coxiella burnetii RSA 493 phosphoribosyl transferase NP_819505.1 411739 R 227377 CDS NP_819507.1 29653815 1208356 414286..416091 1 NC_002971.3 ATP-dependent DNA helicase 416091 recQ 1208356 recQ Coxiella burnetii RSA 493 ATP-dependent DNA helicase NP_819507.1 414286 D 227377 CDS NP_819508.2 215918971 1208357 416156..416545 1 NC_002971.3 DNA-binding protein BpH2 416545 1208357 CBU_0473 Coxiella burnetii RSA 493 DNA-binding protein BpH2 NP_819508.2 416156 D 227377 CDS NP_819509.1 29653817 1208358 416557..416805 1 NC_002971.3 hypothetical protein 416805 1208358 CBU_0474 Coxiella burnetii RSA 493 hypothetical protein NP_819509.1 416557 D 227377 CDS NP_819511.1 29653819 1208360 417287..419029 1 NC_002971.3 hypothetical protein 419029 1208360 CBU_0476 Coxiella burnetii RSA 493 hypothetical protein NP_819511.1 417287 D 227377 CDS NP_819512.1 29653820 1208361 complement(419039..419317) 1 NC_002971.3 hypothetical protein 419317 1208361 CBU_0477 Coxiella burnetii RSA 493 hypothetical protein NP_819512.1 419039 R 227377 CDS NP_819513.1 29653821 1208362 419337..419435 1 NC_002971.3 hypothetical protein 419435 1208362 CBU_0478 Coxiella burnetii RSA 493 hypothetical protein NP_819513.1 419337 D 227377 CDS YP_002332965.1 215918972 7065876 419555..419725 1 NC_002971.3 hypothetical protein 419725 7065876 CBU_0478a Coxiella burnetii RSA 493 hypothetical protein YP_002332965.1 419555 D 227377 CDS NP_819514.2 215918973 1208363 419715..420476 1 NC_002971.3 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 420476 kdsB 1208363 kdsB Coxiella burnetii RSA 493 3-deoxy-manno-octulosonate cytidylyltransferase NP_819514.2 419715 D 227377 CDS NP_819515.1 29653823 1208364 complement(420460..420939) 1 NC_002971.3 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 420939 argR 1208364 argR Coxiella burnetii RSA 493 arginine repressor ArgR NP_819515.1 420460 R 227377 CDS NP_819516.1 29653824 1208365 421033..421785 1 NC_002971.3 arginine ABC transporter ATP-binding protein 421785 artP 1208365 artP Coxiella burnetii RSA 493 arginine ABC transporter ATP-binding protein NP_819516.1 421033 D 227377 CDS NP_819517.1 29653825 1208366 421789..422598 1 NC_002971.3 arginine ABC transporter substrate-binding protein 422598 1208366 CBU_0482 Coxiella burnetii RSA 493 arginine ABC transporter substrate-binding protein NP_819517.1 421789 D 227377 CDS NP_819518.1 29653826 1208367 422598..423263 1 NC_002971.3 arginine ABC transporter permease 423263 artQ 1208367 artQ Coxiella burnetii RSA 493 arginine ABC transporter permease NP_819518.1 422598 D 227377 CDS NP_819519.1 29653827 1208368 423260..423931 1 NC_002971.3 arginine transport system permease 423931 artM 1208368 artM Coxiella burnetii RSA 493 arginine transport system permease NP_819519.1 423260 D 227377 CDS NP_819520.1 29653828 1208369 423944..425560 1 NC_002971.3 hypothetical protein 425560 1208369 CBU_0485 Coxiella burnetii RSA 493 hypothetical protein NP_819520.1 423944 D 227377 CDS NP_819521.1 29653829 1208370 complement(425620..427782) 1 NC_002971.3 ribonuclease 427782 1208370 CBU_0486 Coxiella burnetii RSA 493 ribonuclease NP_819521.1 425620 R 227377 CDS YP_338279.1 77358713 1208371 428111..429037 1 NC_002971.3 ribosomal large subunit pseudouridine synthase C 429037 rluC 1208371 rluC Coxiella burnetii RSA 493 ribosomal large subunit pseudouridine synthase C YP_338279.1 428111 D 227377 CDS NP_819522.1 29653830 1208372 429066..429773 1 NC_002971.3 Ser/Thr protein phosphatase 429773 1208372 CBU_0488 Coxiella burnetii RSA 493 Ser/Thr protein phosphatase NP_819522.1 429066 D 227377 CDS NP_819523.1 29653831 1208373 complement(429865..430899) 1 NC_002971.3 phospholipase A1 430899 1208373 CBU_0489 Coxiella burnetii RSA 493 phospholipase A1 NP_819523.1 429865 R 227377 CDS NP_819524.2 215918974 1208374 complement(430955..432739) 1 NC_002971.3 DNA polymerase X family/PHP domain-containing protein 432739 1208374 CBU_0490 Coxiella burnetii RSA 493 DNA polymerase X family/PHP domain-containing protein NP_819524.2 430955 R 227377 CDS NP_819525.1 29653833 1208375 432883..433077 1 NC_002971.3 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 433077 rpmF 1208375 rpmF Coxiella burnetii RSA 493 50S ribosomal protein L32 NP_819525.1 432883 D 227377 CDS NP_819526.1 29653834 1208376 433085..434116 1 NC_002971.3 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 434116 plsX 1208376 plsX Coxiella burnetii RSA 493 glycerol-3-phosphate acyltransferase PlsX NP_819526.1 433085 D 227377 CDS NP_819527.1 29653835 1208377 434113..435072 1 NC_002971.3 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 435072 fabH 1208377 fabH Coxiella burnetii RSA 493 3-oxoacyl-ACP synthase NP_819527.1 434113 D 227377 CDS NP_819528.1 29653836 1208378 435173..436114 1 NC_002971.3 malonyl CoA-ACP transacylase 436114 fabD 1208378 fabD Coxiella burnetii RSA 493 malonyl CoA-ACP transacylase NP_819528.1 435173 D 227377 CDS NP_819529.1 29653837 1208379 436190..436939 1 NC_002971.3 3-oxoacyl-ACP reductase 436939 fabG 1208379 fabG Coxiella burnetii RSA 493 3-oxoacyl-ACP reductase NP_819529.1 436190 D 227377 CDS NP_819530.1 29653838 1208380 437007..437261 1 NC_002971.3 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 437261 acpP 1208380 acpP Coxiella burnetii RSA 493 acyl carrier protein NP_819530.1 437007 D 227377 CDS NP_819531.1 29653839 1208381 437306..438550 1 NC_002971.3 3-oxoacyl-ACP synthase 438550 fabF 1208381 fabF Coxiella burnetii RSA 493 3-oxoacyl-ACP synthase NP_819531.1 437306 D 227377 CDS NP_819532.1 29653840 1208382 438560..439672 1 NC_002971.3 hypothetical protein 439672 1208382 CBU_0498 Coxiella burnetii RSA 493 hypothetical protein NP_819532.1 438560 D 227377 CDS NP_819533.2 215918975 1208383 439768..440253 1 NC_002971.3 thymidylate kinase 440253 tmk 1208383 tmk Coxiella burnetii RSA 493 thymidylate kinase NP_819533.2 439768 D 227377 CDS NP_819534.1 29653842 1208384 440250..441209 1 NC_002971.3 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 441209 holB 1208384 holB Coxiella burnetii RSA 493 DNA polymerase III subunit delta' NP_819534.1 440250 D 227377 CDS NP_819535.1 29653843 1208385 441228..441353 1 NC_002971.3 hypothetical protein 441353 1208385 CBU_0501 Coxiella burnetii RSA 493 hypothetical protein NP_819535.1 441228 D 227377 CDS NP_819536.2 215918976 1208386 441373..442140 1 NC_002971.3 TatD family hydrolase 442140 1208386 CBU_0502 Coxiella burnetii RSA 493 TatD family hydrolase NP_819536.2 441373 D 227377 CDS NP_819537.1 29653845 1208387 complement(442325..443404) 1 NC_002971.3 glutamine synthetase 443404 glnA 1208387 glnA Coxiella burnetii RSA 493 glutamine synthetase NP_819537.1 442325 R 227377 CDS NP_819538.1 29653846 1208388 complement(443567..445045) 1 NC_002971.3 di-/tripeptide transporter 445045 1208388 CBU_0504 Coxiella burnetii RSA 493 di-/tripeptide transporter NP_819538.1 443567 R 227377 CDS NP_819539.1 29653847 1208389 complement(445165..445782) 1 NC_002971.3 acetyltransferase 445782 1208389 CBU_0505 Coxiella burnetii RSA 493 acetyltransferase NP_819539.1 445165 R 227377 CDS YP_002332966.1 215918977 7065882 446054..446164 1 NC_002971.3 hypothetical protein 446164 7065882 CBU_0505a Coxiella burnetii RSA 493 hypothetical protein YP_002332966.1 446054 D 227377 CDS NP_819540.1 29653848 1208390 446222..447946 1 NC_002971.3 single-stranded-DNA-specific exonuclease 447946 recJ 1208390 recJ Coxiella burnetii RSA 493 single-stranded-DNA-specific exonuclease NP_819540.1 446222 D 227377 CDS NP_819541.1 29653849 1208391 complement(448018..449058) 1 NC_002971.3 hypothetical protein 449058 1208391 CBU_0507 Coxiella burnetii RSA 493 hypothetical protein NP_819541.1 448018 R 227377 CDS NP_819542.1 29653850 1208392 complement(449267..449980) 1 NC_002971.3 hypothetical protein 449980 1208392 CBU_0508 Coxiella burnetii RSA 493 hypothetical protein NP_819542.1 449267 R 227377 CDS NP_819543.1 29653851 1208393 450030..450374 1 NC_002971.3 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 450374 trpR 1208393 trpR Coxiella burnetii RSA 493 Trp operon repressor NP_819543.1 450030 D 227377 CDS NP_819544.1 29653852 1208394 450387..450689 1 NC_002971.3 hypothetical protein 450689 1208394 CBU_0510 Coxiella burnetii RSA 493 hypothetical protein NP_819544.1 450387 D 227377 CDS YP_002332967.1 215918978 7065868 450860..450979 1 NC_002971.3 hypothetical protein 450979 7065868 CBU_0510a Coxiella burnetii RSA 493 hypothetical protein YP_002332967.1 450860 D 227377 CDS NP_819545.1 29653853 1208397 453557..454705 1 NC_002971.3 fructose-1,6-bisphosphatase 454705 1208397 CBU_0513 Coxiella burnetii RSA 493 fructose-1,6-bisphosphatase NP_819545.1 453557 D 227377 CDS NP_819546.1 29653854 1208398 454705..455496 1 NC_002971.3 hypothetical protein 455496 1208398 CBU_0514 Coxiella burnetii RSA 493 hypothetical protein NP_819546.1 454705 D 227377 CDS YP_002332968.1 215918979 7065957 455750..455860 1 NC_002971.3 hypothetical protein 455860 7065957 CBU_0514a Coxiella burnetii RSA 493 hypothetical protein YP_002332968.1 455750 D 227377 CDS NP_819547.2 215918980 1208399 456167..457486 1 NC_002971.3 MFS superfamily transporter 457486 1208399 CBU_0515 Coxiella burnetii RSA 493 MFS superfamily transporter NP_819547.2 456167 D 227377 CDS NP_819548.1 29653856 1208400 457584..457700 1 NC_002971.3 hypothetical protein 457700 1208400 CBU_0516 Coxiella burnetii RSA 493 hypothetical protein NP_819548.1 457584 D 227377 CDS YP_002332969.1 215918981 7065956 complement(457880..458236) 1 NC_002971.3 hypothetical protein 458236 7065956 CBU_0516a Coxiella burnetii RSA 493 hypothetical protein YP_002332969.1 457880 R 227377 CDS NP_819549.2 215918982 1208402 complement(458719..459990) 1 NC_002971.3 succinyldiaminopimelate aminotransferase; aspartate aminotransferase 459990 aspB 1208402 aspB Coxiella burnetii RSA 493 aspartate aminotransferase NP_819549.2 458719 R 227377 CDS NP_819550.1 29653858 1208403 459984..462002 1 NC_002971.3 'The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion'; excinuclease ABC subunit B 462002 uvrB 1208403 uvrB Coxiella burnetii RSA 493 excinuclease ABC subunit B NP_819550.1 459984 D 227377 CDS NP_819551.1 29653859 1208404 462062..462670 1 NC_002971.3 DedA family protein 462670 1208404 CBU_0519 Coxiella burnetii RSA 493 DedA family protein NP_819551.1 462062 D 227377 CDS NP_819552.2 215918983 1208405 complement(462700..463599) 1 NC_002971.3 hydroxymethylglutaryl-CoA lyase 463599 leuA 1208405 leuA Coxiella burnetii RSA 493 hydroxymethylglutaryl-CoA lyase NP_819552.2 462700 R 227377 CDS NP_819553.2 215918984 1208406 complement(463586..465040) 1 NC_002971.3 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; N-ethylammeline chlorohydrolase 465040 1208406 CBU_0521 Coxiella burnetii RSA 493 N-ethylammeline chlorohydrolase NP_819553.2 463586 R 227377 CDS NP_819554.1 29653862 1208407 465216..465386 1 NC_002971.3 hypothetical protein 465386 1208407 CBU_0522 Coxiella burnetii RSA 493 hypothetical protein NP_819554.1 465216 D 227377 CDS YP_002332970.1 215918985 7065927 465582..465854 1 NC_002971.3 hypothetical protein 465854 7065927 CBU_0522a Coxiella burnetii RSA 493 hypothetical protein YP_002332970.1 465582 D 227377 CDS NP_819555.2 215918986 1208408 complement(465851..466945) 1 NC_002971.3 IS1111A transposase 466945 1208408 CBU_0523 Coxiella burnetii RSA 493 IS1111A transposase NP_819555.2 465851 R 227377 CDS NP_819556.2 215918987 1208409 467155..469707 1 NC_002971.3 DNA gyrase subunit A 469707 gyrA 1208409 gyrA Coxiella burnetii RSA 493 DNA gyrase subunit A NP_819556.2 467155 D 227377 CDS NP_819557.1 29653865 1208410 469768..470850 1 NC_002971.3 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 470850 serC 1208410 serC Coxiella burnetii RSA 493 phosphoserine aminotransferase NP_819557.1 469768 D 227377 CDS NP_819558.1 29653866 1208411 470856..472172 1 NC_002971.3 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 472172 aroA 1208411 aroA Coxiella burnetii RSA 493 3-phosphoshikimate 1-carboxyvinyltransferase NP_819558.1 470856 D 227377 CDS NP_819559.1 29653867 1208412 472173..472886 1 NC_002971.3 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 472886 cmk 1208412 cmk Coxiella burnetii RSA 493 cytidylate kinase NP_819559.1 472173 D 227377 CDS NP_819560.2 215918988 1208413 473018..474685 1 NC_002971.3 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 474685 rpsA 1208413 rpsA Coxiella burnetii RSA 493 30S ribosomal protein S1 NP_819560.2 473018 D 227377 CDS NP_819561.1 29653869 1208414 474840..475130 1 NC_002971.3 hypothetical protein 475130 1208414 CBU_0529 Coxiella burnetii RSA 493 hypothetical protein NP_819561.1 474840 D 227377 CDS NP_819562.2 215918989 1208415 475127..476296 1 NC_002971.3 hypothetical protein 476296 1208415 CBU_0530 Coxiella burnetii RSA 493 hypothetical protein NP_819562.2 475127 D 227377 CDS NP_819563.1 29653871 1208416 476300..477010 1 NC_002971.3 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 477010 pyrF 1208416 pyrF Coxiella burnetii RSA 493 orotidine 5'-phosphate decarboxylase NP_819563.1 476300 D 227377 CDS NP_819564.2 215918990 1208417 477073..477444 1 NC_002971.3 competence protein ComEA, helix-hairpin-helix repeat region 477444 1208417 CBU_0532 Coxiella burnetii RSA 493 competence protein ComEA, helix-hairpin-helix repeat region NP_819564.2 477073 D 227377 CDS NP_819565.1 29653873 1208418 477656..478723 1 NC_002971.3 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 478723 rfe 1208418 rfe Coxiella burnetii RSA 493 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase NP_819565.1 477656 D 227377 CDS NP_819566.1 29653874 1208419 complement(478846..480042) 1 NC_002971.3 hypothetical protein 480042 1208419 CBU_0534 Coxiella burnetii RSA 493 hypothetical protein NP_819566.1 478846 R 227377 CDS NP_819567.1 29653875 1208420 480220..481191 1 NC_002971.3 sporulation and cell division repeat protein 481191 1208420 CBU_0535 Coxiella burnetii RSA 493 sporulation and cell division repeat protein NP_819567.1 480220 D 227377 CDS NP_819568.1 29653876 1208421 complement(481225..481347) 1 NC_002971.3 hypothetical protein 481347 1208421 CBU_0536 Coxiella burnetii RSA 493 hypothetical protein NP_819568.1 481225 R 227377 CDS NP_819569.1 29653877 1208422 481372..481545 1 NC_002971.3 hypothetical protein 481545 1208422 CBU_0537 Coxiella burnetii RSA 493 hypothetical protein NP_819569.1 481372 D 227377 CDS NP_819570.1 29653878 1208423 481714..481806 1 NC_002971.3 hypothetical protein 481806 1208423 CBU_0538 Coxiella burnetii RSA 493 hypothetical protein NP_819570.1 481714 D 227377 CDS NP_819571.2 215918991 1208424 481875..483482 1 NC_002971.3 tripeptide permease TppB 483482 1208424 CBU_0539 Coxiella burnetii RSA 493 tripeptide permease TppB NP_819571.2 481875 D 227377 CDS NP_819572.1 29653880 1208425 483661..487170 1 NC_002971.3 chromosome segregation protein SMC 487170 smc 1208425 smc Coxiella burnetii RSA 493 chromosome segregation protein SMC NP_819572.1 483661 D 227377 CDS NP_819573.2 215918992 1208426 487225..487917 1 NC_002971.3 cell division protein ZipA 487917 zipA 1208426 zipA Coxiella burnetii RSA 493 cell division protein ZipA NP_819573.2 487225 D 227377 CDS NP_819574.2 215918993 1208427 487918..489939 1 NC_002971.3 NAD-dependent DNA ligase 489939 ligA 1208427 ligA Coxiella burnetii RSA 493 NAD-dependent DNA ligase NP_819574.2 487918 D 227377 CDS NP_819575.1 29653883 1208428 490170..493025 1 NC_002971.3 hypothetical protein 493025 1208428 CBU_0543 Coxiella burnetii RSA 493 hypothetical protein NP_819575.1 490170 D 227377 CDS NP_819576.1 29653884 1208429 493270..493551 1 NC_002971.3 hypothetical protein 493551 1208429 CBU_0544 Coxiella burnetii RSA 493 hypothetical protein NP_819576.1 493270 D 227377 CDS NP_819577.2 215918994 1208430 493610..494257 1 NC_002971.3 LemA family protein 494257 lemA 1208430 lemA Coxiella burnetii RSA 493 LemA family protein NP_819577.2 493610 D 227377 CDS NP_819578.1 29653886 1208431 494267..495313 1 NC_002971.3 metalloprotease; heat shock protein HtpX 495313 htpX 1208431 htpX Coxiella burnetii RSA 493 heat shock protein HtpX NP_819578.1 494267 D 227377 CDS NP_819579.1 29653887 1208432 complement(495354..497039) 1 NC_002971.3 hypothetical protein 497039 1208432 CBU_0547 Coxiella burnetii RSA 493 hypothetical protein NP_819579.1 495354 R 227377 CDS NP_819580.1 29653888 1208433 complement(497020..498024) 1 NC_002971.3 lytic murein transglycosylase B 498024 1208433 CBU_0548 Coxiella burnetii RSA 493 lytic murein transglycosylase B NP_819580.1 497020 R 227377 CDS NP_819581.2 215918995 1208434 complement(498104..499252) 1 NC_002971.3 rod shape-determining protein 499252 rodA 1208434 rodA Coxiella burnetii RSA 493 rod shape-determining protein NP_819581.2 498104 R 227377 CDS NP_819582.2 215918996 1208435 complement(499295..501142) 1 NC_002971.3 penicillin-binding protein 501142 pbpA 1208435 pbpA Coxiella burnetii RSA 493 penicillin-binding protein NP_819582.2 499295 R 227377 CDS NP_819583.1 29653891 1208437 complement(501618..501968) 1 NC_002971.3 iojap family protein 501968 1208437 CBU_0552 Coxiella burnetii RSA 493 iojap family protein NP_819583.1 501618 R 227377 CDS NP_819585.2 215918997 1208439 502093..503187 1 NC_002971.3 IS1111A transposase 503187 1208439 CBU_0554 Coxiella burnetii RSA 493 IS1111A transposase NP_819585.2 502093 D 227377 CDS YP_002332971.1 215918998 7065959 complement(503184..503456) 1 NC_002971.3 hypothetical protein 503456 7065959 CBU_0554a Coxiella burnetii RSA 493 hypothetical protein YP_002332971.1 503184 R 227377 CDS NP_819586.1 29653894 1208440 complement(503550..503753) 1 NC_002971.3 hypothetical protein 503753 1208440 CBU_0555 Coxiella burnetii RSA 493 hypothetical protein NP_819586.1 503550 R 227377 CDS NP_819587.2 215918999 1208441 complement(503959..504627) 1 NC_002971.3 nicotinate (nicotinamide) nucleotide adenylyltransferase 504627 nadD 1208441 nadD Coxiella burnetii RSA 493 nicotinate (nicotinamide) nucleotide adenylyltransferase NP_819587.2 503959 R 227377 CDS NP_819588.1 29653896 1208442 complement(504608..505627) 1 NC_002971.3 DNA polymerase III subunit delta 505627 holA 1208442 holA Coxiella burnetii RSA 493 DNA polymerase III subunit delta NP_819588.1 504608 R 227377 CDS NP_819589.1 29653897 1208443 complement(505630..506181) 1 NC_002971.3 rare lipoprotein B 506181 1208443 CBU_0558 Coxiella burnetii RSA 493 rare lipoprotein B NP_819589.1 505630 R 227377 CDS NP_819590.1 29653898 1208444 complement(506171..508633) 1 NC_002971.3 'leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase'; leucyl-tRNA synthetase 508633 leuS 1208444 leuS Coxiella burnetii RSA 493 leucyl-tRNA synthetase NP_819590.1 506171 R 227377 CDS NP_819591.1 29653899 1208445 508773..510005 1 NC_002971.3 hypothetical protein 510005 1208445 CBU_0560 Coxiella burnetii RSA 493 hypothetical protein NP_819591.1 508773 D 227377 CDS NP_819592.1 29653900 1208447 complement(510895..512175) 1 NC_002971.3 ATP-binding protein 512175 1208447 CBU_0562 Coxiella burnetii RSA 493 ATP-binding protein NP_819592.1 510895 R 227377 CDS YP_002332972.1 215919000 7065866 complement(512405..512827) 1 NC_002971.3 hypothetical protein 512827 7065866 CBU_0562a Coxiella burnetii RSA 493 hypothetical protein YP_002332972.1 512405 R 227377 CDS NP_819593.1 29653901 1208448 complement(512817..513032) 1 NC_002971.3 hypothetical protein 513032 1208448 CBU_0563 Coxiella burnetii RSA 493 hypothetical protein NP_819593.1 512817 R 227377 CDS NP_819594.1 29653902 1208449 complement(513052..514509) 1 NC_002971.3 apolipoprotein N-acyltransferase 514509 cutE 1208449 cutE Coxiella burnetii RSA 493 apolipoprotein N-acyltransferase NP_819594.1 513052 R 227377 CDS NP_819595.2 215919001 1208450 complement(514502..515353) 1 NC_002971.3 hypothetical protein 515353 corC 1208450 corC Coxiella burnetii RSA 493 hypothetical protein NP_819595.2 514502 R 227377 CDS NP_819596.1 29653904 1208451 complement(515396..516661) 1 NC_002971.3 MFS superfamily transporter 516661 1208451 CBU_0566 Coxiella burnetii RSA 493 MFS superfamily transporter NP_819596.1 515396 R 227377 CDS NP_819597.1 29653905 1208452 complement(516717..517175) 1 NC_002971.3 hypothetical protein 517175 1208452 CBU_0567 Coxiella burnetii RSA 493 hypothetical protein NP_819597.1 516717 R 227377 CDS NP_819598.1 29653906 1208453 complement(517172..518143) 1 NC_002971.3 PhoH-like protein 518143 1208453 CBU_0568 Coxiella burnetii RSA 493 PhoH-like protein NP_819598.1 517172 R 227377 CDS NP_819599.1 29653907 1208454 complement(518154..519473) 1 NC_002971.3 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 519473 1208454 CBU_0569 Coxiella burnetii RSA 493 (dimethylallyl)adenosine tRNA methylthiotransferase NP_819599.1 518154 R 227377 CDS NP_819600.1 29653908 1208455 complement(519494..521176) 1 NC_002971.3 amino acid permease 521176 1208455 CBU_0570 Coxiella burnetii RSA 493 amino acid permease NP_819600.1 519494 R 227377 CDS NP_819601.1 29653909 1208456 complement(521391..521816) 1 NC_002971.3 hypothetical protein 521816 1208456 CBU_0571 Coxiella burnetii RSA 493 hypothetical protein NP_819601.1 521391 R 227377 CDS NP_819602.1 29653910 1208457 522138..523514 1 NC_002971.3 cytosol aminopeptidase 523514 1208457 CBU_0572 Coxiella burnetii RSA 493 cytosol aminopeptidase NP_819602.1 522138 D 227377 CDS NP_819603.1 29653911 1208458 523524..525671 1 NC_002971.3 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 525671 fadE 1208458 fadE Coxiella burnetii RSA 493 acyl-CoA dehydrogenase NP_819603.1 523524 D 227377 CDS NP_819604.1 29653912 1208459 526216..527511 1 NC_002971.3 'Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation'; acetyl-CoA acetyltransferase 527511 1208459 CBU_0574 Coxiella burnetii RSA 493 acetyl-CoA acetyltransferase NP_819604.1 526216 D 227377 CDS NP_819606.2 215919002 1208461 527562..529613 1 NC_002971.3 fatty oxidation complex subunit alpha 529613 yfcX 1208461 yfcX Coxiella burnetii RSA 493 fatty oxidation complex subunit alpha NP_819606.2 527562 D 227377 CDS NP_819607.2 215919003 1208462 529601..530377 1 NC_002971.3 hypothetical protein 530377 1208462 CBU_0577 Coxiella burnetii RSA 493 hypothetical protein NP_819607.2 529601 D 227377 CDS NP_819608.1 29653916 1208463 complement(530390..531364) 1 NC_002971.3 polyprenyl-phosphate beta-D-glucosyltransferase 531364 1208463 CBU_0578 Coxiella burnetii RSA 493 polyprenyl-phosphate beta-D-glucosyltransferase NP_819608.1 530390 R 227377 CDS NP_819609.1 29653917 1208464 complement(531351..532844) 1 NC_002971.3 undecaprenyl-phosphomannose:protein mannosyltransferase 532844 1208464 CBU_0579 Coxiella burnetii RSA 493 undecaprenyl-phosphomannose:protein mannosyltransferase NP_819609.1 531351 R 227377 CDS NP_819610.1 29653918 1208465 532969..533790 1 NC_002971.3 hypothetical protein 533790 1208465 CBU_0580 Coxiella burnetii RSA 493 hypothetical protein NP_819610.1 532969 D 227377 CDS NP_819611.1 29653919 1208466 complement(533760..534095) 1 NC_002971.3 ferredoxin 534095 1208466 CBU_0581 Coxiella burnetii RSA 493 ferredoxin NP_819611.1 533760 R 227377 CDS NP_819612.1 29653920 1208467 534168..534407 1 NC_002971.3 BolA family protein 534407 bolA 1208467 bolA Coxiella burnetii RSA 493 BolA family protein NP_819612.1 534168 D 227377 CDS NP_819613.1 29653921 1208468 534410..534709 1 NC_002971.3 glutaredoxin family protein 534709 1208468 CBU_0583 Coxiella burnetii RSA 493 glutaredoxin family protein NP_819613.1 534410 D 227377 CDS NP_819614.1 29653922 1208469 534906..535223 1 NC_002971.3 hypothetical protein 535223 1208469 CBU_0584 Coxiella burnetii RSA 493 hypothetical protein NP_819614.1 534906 D 227377 CDS NP_819615.1 29653923 1208470 complement(535266..535469) 1 NC_002971.3 hypothetical protein 535469 1208470 CBU_0585 Coxiella burnetii RSA 493 hypothetical protein NP_819615.1 535266 R 227377 CDS NP_819616.1 29653924 1208471 535521..539036 1 NC_002971.3 pyridine nucleotide-disulfide oxidoreductase 539036 1208471 CBU_0586 Coxiella burnetii RSA 493 pyridine nucleotide-disulfide oxidoreductase NP_819616.1 535521 D 227377 CDS NP_819617.1 29653925 1208472 539081..539404 1 NC_002971.3 thiosulfate sulfurtransferase 539404 glpE 1208472 glpE Coxiella burnetii RSA 493 thiosulfate sulfurtransferase NP_819617.1 539081 D 227377 CDS NP_819618.1 29653926 1208473 539484..540479 1 NC_002971.3 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 540479 nadA 1208473 nadA Coxiella burnetii RSA 493 quinolinate synthetase NP_819618.1 539484 D 227377 CDS NP_819619.1 29653927 1208474 540476..540874 1 NC_002971.3 (2Fe-2S) ferredoxin 540874 1208474 CBU_0589 Coxiella burnetii RSA 493 (2Fe-2S) ferredoxin NP_819619.1 540476 D 227377 CDS NP_819620.1 29653928 1208475 540871..541044 1 NC_002971.3 hypothetical protein 541044 1208475 CBU_0590 Coxiella burnetii RSA 493 hypothetical protein NP_819620.1 540871 D 227377 CDS NP_819621.1 29653929 1208476 541051..541875 1 NC_002971.3 hypothetical protein 541875 1208476 CBU_0591 Coxiella burnetii RSA 493 hypothetical protein NP_819621.1 541051 D 227377 CDS NP_819622.2 215919004 1208477 541877..542194 1 NC_002971.3 hypothetical protein 542194 1208477 CBU_0592 Coxiella burnetii RSA 493 hypothetical protein NP_819622.2 541877 D 227377 CDS NP_819626.1 29653934 1208481 complement(543314..544063) 1 NC_002971.3 metallo-beta-lactamase 544063 1208481 CBU_0596 Coxiella burnetii RSA 493 metallo-beta-lactamase NP_819626.1 543314 R 227377 CDS YP_002332973.1 215919005 7065892 544319..544558 1 NC_002971.3 hypothetical protein 544558 7065892 CBU_0596a Coxiella burnetii RSA 493 hypothetical protein YP_002332973.1 544319 D 227377 CDS NP_819627.1 29653935 1208482 complement(544676..545803) 1 NC_002971.3 oxygen-independent coproporphyrinogen III oxidase 545803 1208482 CBU_0597 Coxiella burnetii RSA 493 oxygen-independent coproporphyrinogen III oxidase NP_819627.1 544676 R 227377 CDS NP_819628.2 215919006 1208483 545856..546419 1 NC_002971.3 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 546419 nudE 1208483 nudE Coxiella burnetii RSA 493 ADP-ribose diphosphatase NudE NP_819628.2 545856 D 227377 CDS NP_819629.1 29653937 1208484 546409..547224 1 NC_002971.3 myo-inositol 1-(4-)phosphatase; 3'(2'),5'-bisphosphate nucleotidase 547224 cysQ-1 1208484 cysQ-1 Coxiella burnetii RSA 493 3'(2'),5'-bisphosphate nucleotidase NP_819629.1 546409 D 227377 CDS NP_819637.1 29653945 1208492 complement(551922..553433) 1 NC_002971.3 diphosphomevalonate decarboxylase/isopentenyl-diphosphate delta-isomerase 553433 mvaD 1208492 mvaD Coxiella burnetii RSA 493 diphosphomevalonate decarboxylase/isopentenyl-diphosphate delta-isomerase NP_819637.1 551922 R 227377 CDS NP_819638.1 29653946 1208493 complement(553426..554367) 1 NC_002971.3 mevalonate kinase 554367 1208493 CBU_0608 Coxiella burnetii RSA 493 mevalonate kinase NP_819638.1 553426 R 227377 CDS NP_819639.1 29653947 1208494 complement(554466..555488) 1 NC_002971.3 phopshomevalonate kinase 555488 1208494 CBU_0609 Coxiella burnetii RSA 493 phopshomevalonate kinase NP_819639.1 554466 R 227377 CDS NP_819640.1 29653948 1208495 complement(555485..556558) 1 NC_002971.3 hydroxymethylglutaryl-CoA reductase (NADPH) 556558 1208495 CBU_0610 Coxiella burnetii RSA 493 hydroxymethylglutaryl-CoA reductase (NADPH) NP_819640.1 555485 R 227377 CDS NP_819641.1 29653949 1208496 556738..559149 1 NC_002971.3 hypothetical protein 559149 yaeT 1208496 yaeT Coxiella burnetii RSA 493 hypothetical protein NP_819641.1 556738 D 227377 CDS NP_819642.1 29653950 1208497 559227..559724 1 NC_002971.3 outer membrane chaperone protein Skp 559724 ompH 1208497 ompH Coxiella burnetii RSA 493 outer membrane chaperone protein Skp NP_819642.1 559227 D 227377 CDS NP_819643.1 29653951 1208498 559734..560762 1 NC_002971.3 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 560762 lpxD 1208498 lpxD Coxiella burnetii RSA 493 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_819643.1 559734 D 227377 CDS NP_819644.1 29653952 1208499 560759..561196 1 NC_002971.3 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 561196 fabZ 1208499 fabZ Coxiella burnetii RSA 493 (3R)-hydroxymyristoyl-ACP dehydratase NP_819644.1 560759 D 227377 CDS NP_819645.1 29653953 1208500 561201..561980 1 NC_002971.3 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 561980 lpxA 1208500 lpxA Coxiella burnetii RSA 493 UDP-N-acetylglucosamine acyltransferase NP_819645.1 561201 D 227377 CDS NP_819646.1 29653954 1208501 561977..562567 1 NC_002971.3 hydrolase 562567 1208501 CBU_0616 Coxiella burnetii RSA 493 hydrolase NP_819646.1 561977 D 227377 CDS NP_819647.2 215919007 1208502 complement(562660..564177) 1 NC_002971.3 hypothetical protein 564177 1208502 CBU_0617 Coxiella burnetii RSA 493 hypothetical protein NP_819647.2 562660 R 227377 CDS NP_819648.2 215919008 1208503 complement(564182..565276) 1 NC_002971.3 acyltransferase 565276 1208503 CBU_0618 Coxiella burnetii RSA 493 acyltransferase NP_819648.2 564182 R 227377 CDS NP_819649.1 29653957 1208504 complement(565332..565820) 1 NC_002971.3 hypothetical protein 565820 1208504 CBU_0619 Coxiella burnetii RSA 493 hypothetical protein NP_819649.1 565332 R 227377 CDS NP_819650.1 29653958 1208505 complement(565978..567108) 1 NC_002971.3 'catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM'; lipid-A-disaccharide synthase 567108 lpxB 1208505 lpxB Coxiella burnetii RSA 493 lipid-A-disaccharide synthase NP_819650.1 565978 R 227377 CDS NP_819651.1 29653959 1208506 complement(567098..568081) 1 NC_002971.3 oxidoreductase, NAD-binding 568081 1208506 CBU_0621 Coxiella burnetii RSA 493 oxidoreductase, NAD-binding NP_819651.1 567098 R 227377 CDS NP_819652.2 215919009 1208507 568273..568719 1 NC_002971.3 zinc-binding domain-containing protein 568719 1208507 CBU_0622 Coxiella burnetii RSA 493 zinc-binding domain-containing protein NP_819652.2 568273 D 227377 CDS NP_819653.1 29653961 1208508 568724..568846 1 NC_002971.3 hypothetical protein 568846 1208508 CBU_0623 Coxiella burnetii RSA 493 hypothetical protein NP_819653.1 568724 D 227377 CDS NP_819654.1 29653962 1208509 568946..569080 1 NC_002971.3 hypothetical protein 569080 1208509 CBU_0624 Coxiella burnetii RSA 493 hypothetical protein NP_819654.1 568946 D 227377 CDS NP_819655.1 29653963 1208510 569281..569688 1 NC_002971.3 hypothetical protein 569688 1208510 CBU_0625 Coxiella burnetii RSA 493 hypothetical protein NP_819655.1 569281 D 227377 CDS NP_819656.1 29653964 1208511 569797..571884 1 NC_002971.3 hypothetical protein 571884 1208511 CBU_0626 Coxiella burnetii RSA 493 hypothetical protein NP_819656.1 569797 D 227377 CDS NP_819657.1 29653965 1208512 complement(572010..572132) 1 NC_002971.3 hypothetical protein 572132 1208512 CBU_0627 Coxiella burnetii RSA 493 hypothetical protein NP_819657.1 572010 R 227377 CDS NP_819658.1 29653966 1208513 572267..572794 1 NC_002971.3 inorganic diphosphatase 572794 ppa 1208513 ppa Coxiella burnetii RSA 493 inorganic diphosphatase NP_819658.1 572267 D 227377 CDS NP_819659.1 29653967 1208514 572913..576053 1 NC_002971.3 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 576053 putA 1208514 putA Coxiella burnetii RSA 493 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase NP_819659.1 572913 D 227377 CDS NP_819660.1 29653968 1208515 576126..576818 1 NC_002971.3 peptidyl-prolyl cis-trans isomerase Mip 576818 mip 1208515 mip Coxiella burnetii RSA 493 peptidyl-prolyl cis-trans isomerase Mip NP_819660.1 576126 D 227377 CDS NP_819661.2 215919010 1208516 576860..580834 1 NC_002971.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 580834 purL 1208516 purL Coxiella burnetii RSA 493 phosphoribosylformylglycinamidine synthase NP_819661.2 576860 D 227377 CDS NP_819662.1 29653970 1208517 complement(580894..581193) 1 NC_002971.3 hypothetical protein 581193 1208517 CBU_0632 Coxiella burnetii RSA 493 hypothetical protein NP_819662.1 580894 R 227377 CDS NP_819664.2 215919011 1208519 581377..583269 1 NC_002971.3 aerobic respiration control sensor protein arcB 583269 1208519 CBU_0634 Coxiella burnetii RSA 493 aerobic respiration control sensor protein arcB NP_819664.2 581377 D 227377 CDS NP_819665.1 29653973 1208520 583288..584778 1 NC_002971.3 hypothetical protein 584778 1208520 CBU_0635 Coxiella burnetii RSA 493 hypothetical protein NP_819665.1 583288 D 227377 CDS NP_819666.1 29653974 1208521 584821..585714 1 NC_002971.3 transporter, UAA family 585714 1208521 CBU_0636 Coxiella burnetii RSA 493 transporter, UAA family NP_819666.1 584821 D 227377 CDS NP_819667.1 29653975 1208522 complement(585733..586494) 1 NC_002971.3 coenzyme PQQ synthesis protein C 586494 1208522 CBU_0637 Coxiella burnetii RSA 493 coenzyme PQQ synthesis protein C NP_819667.1 585733 R 227377 CDS NP_819668.1 29653976 1208523 complement(586912..588048) 1 NC_002971.3 branched-chain alpha-keto acid dehydrogenase subunit E2 588048 1208523 CBU_0638 Coxiella burnetii RSA 493 branched-chain alpha-keto acid dehydrogenase subunit E2 NP_819668.1 586912 R 227377 CDS NP_819669.1 29653977 1208524 complement(588048..589028) 1 NC_002971.3 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit beta 589028 1208524 CBU_0639 Coxiella burnetii RSA 493 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit beta NP_819669.1 588048 R 227377 CDS NP_819670.1 29653978 1208525 complement(589233..590339) 1 NC_002971.3 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha 590339 1208525 CBU_0640 Coxiella burnetii RSA 493 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha NP_819670.1 589233 R 227377 CDS NP_819671.2 215919012 1208526 complement(590336..591484) 1 NC_002971.3 leucine dehydrogenase 591484 1208526 CBU_0641 Coxiella burnetii RSA 493 leucine dehydrogenase NP_819671.2 590336 R 227377 CDS NP_819672.1 29653980 1208527 591520..592272 1 NC_002971.3 glycerophosphoryl diester phosphodiesterase 592272 1208527 CBU_0642 Coxiella burnetii RSA 493 glycerophosphoryl diester phosphodiesterase NP_819672.1 591520 D 227377 CDS NP_819673.1 29653981 1208528 592269..593333 1 NC_002971.3 diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase 593333 ribD 1208528 ribD Coxiella burnetii RSA 493 5-amino-6-(5-phosphoribosylamino)uracil reductase NP_819673.1 592269 D 227377 CDS NP_819674.1 29653982 1208529 complement(593311..593649) 1 NC_002971.3 plasmid stabilization system toxin protein 593649 1208529 CBU_0644 Coxiella burnetii RSA 493 plasmid stabilization system toxin protein NP_819674.1 593311 R 227377 CDS NP_819675.1 29653983 1208530 complement(593655..593918) 1 NC_002971.3 prevent-host-death family protein 593918 1208530 CBU_0645 Coxiella burnetii RSA 493 prevent-host-death family protein NP_819675.1 593655 R 227377 CDS NP_819676.2 215919013 1208531 594273..594896 1 NC_002971.3 'catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine'; riboflavin synthase subunit alpha 594896 ribE 1208531 ribE Coxiella burnetii RSA 493 riboflavin synthase subunit alpha NP_819676.2 594273 D 227377 CDS NP_819677.2 215919014 1208532 594937..596100 1 NC_002971.3 3,4-dihydroxy-2-butanone 4-phosphate synthase 596100 ribA 1208532 ribA Coxiella burnetii RSA 493 3,4-dihydroxy-2-butanone 4-phosphate synthase NP_819677.2 594937 D 227377 CDS NP_819678.1 29653986 1208533 596097..596552 1 NC_002971.3 'RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not'; 6,7-dimethyl-8-ribityllumazine synthase 596552 ribH 1208533 ribH Coxiella burnetii RSA 493 6,7-dimethyl-8-ribityllumazine synthase NP_819678.1 596097 D 227377 CDS NP_819679.1 29653987 1208534 596545..597636 1 NC_002971.3 riboflavin transporter 597636 1208534 CBU_0649 Coxiella burnetii RSA 493 riboflavin transporter NP_819679.1 596545 D 227377 CDS NP_819686.1 29653994 1208541 complement(601425..601757) 1 NC_002971.3 hypothetical protein 601757 1208541 CBU_0656 Coxiella burnetii RSA 493 hypothetical protein NP_819686.1 601425 R 227377 CDS NP_819687.1 29653995 1208542 complement(601771..602376) 1 NC_002971.3 'involved in a recombinational process of DNA repair, independent of the recBC complex'; recombination protein RecR 602376 recR 1208542 recR Coxiella burnetii RSA 493 recombination protein RecR NP_819687.1 601771 R 227377 CDS NP_819688.1 29653996 1208543 complement(602388..602819) 1 NC_002971.3 hypothetical protein 602819 1208543 CBU_0658 Coxiella burnetii RSA 493 hypothetical protein NP_819688.1 602388 R 227377 CDS NP_819689.1 29653997 1208544 complement(602929..604458) 1 NC_002971.3 DNA polymerase III subunits gamma and tau 604458 dnaZX 1208544 dnaZX Coxiella burnetii RSA 493 DNA polymerase III subunits gamma and tau NP_819689.1 602929 R 227377 CDS NP_819690.1 29653998 1208545 complement(604462..604626) 1 NC_002971.3 hypothetical protein 604626 1208545 CBU_0660 Coxiella burnetii RSA 493 hypothetical protein NP_819690.1 604462 R 227377 CDS NP_819691.1 29653999 1208547 605024..605434 1 NC_002971.3 hypothetical protein 605434 1208547 CBU_0661 Coxiella burnetii RSA 493 hypothetical protein NP_819691.1 605024 D 227377 CDS NP_819692.1 29654000 1208548 605424..605540 1 NC_002971.3 hypothetical protein 605540 1208548 CBU_0662 Coxiella burnetii RSA 493 hypothetical protein NP_819692.1 605424 D 227377 CDS NP_819693.1 29654001 1208549 605572..605676 1 NC_002971.3 hypothetical protein 605676 1208549 CBU_0663 Coxiella burnetii RSA 493 hypothetical protein NP_819693.1 605572 D 227377 CDS NP_819694.1 29654002 1208550 605781..606926 1 NC_002971.3 ISAs1 family transposase 606926 1208550 CBU_0664 Coxiella burnetii RSA 493 ISAs1 family transposase NP_819694.1 605781 D 227377 CDS NP_819695.1 29654003 1208551 607018..608004 1 NC_002971.3 hypothetical protein 608004 1208551 CBU_0665 Coxiella burnetii RSA 493 hypothetical protein NP_819695.1 607018 D 227377 CDS NP_819696.1 29654004 1208552 complement(608018..609142) 1 NC_002971.3 'dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.'; succinyl-diaminopimelate desuccinylase 609142 dapE 1208552 dapE Coxiella burnetii RSA 493 succinyl-diaminopimelate desuccinylase NP_819696.1 608018 R 227377 CDS NP_819697.1 29654005 1208553 complement(609148..609963) 1 NC_002971.3 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 609963 dapD 1208553 dapD Coxiella burnetii RSA 493 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase NP_819697.1 609148 R 227377 CDS NP_819698.1 29654006 1208554 complement(609960..610139) 1 NC_002971.3 hypothetical protein 610139 1208554 CBU_0668 Coxiella burnetii RSA 493 hypothetical protein NP_819698.1 609960 R 227377 CDS NP_819699.1 29654007 1208555 610139..610312 1 NC_002971.3 hypothetical protein 610312 1208555 CBU_0669 Coxiella burnetii RSA 493 hypothetical protein NP_819699.1 610139 D 227377 CDS NP_819700.2 215919015 1208557 610563..611825 1 NC_002971.3 ATP-dependent RNA helicase rhlE 611825 rhlE 1208557 rhlE Coxiella burnetii RSA 493 ATP-dependent RNA helicase rhlE NP_819700.2 610563 D 227377 CDS NP_819701.1 29654009 1208560 612249..613682 1 NC_002971.3 mannose-6-phosphate isomerase; mannose-1-phosphate guanylyltransferase 613682 rfbA 1208560 rfbA Coxiella burnetii RSA 493 mannose-1-phosphate guanylyltransferase NP_819701.1 612249 D 227377 CDS NP_819702.1 29654010 1208561 complement(613668..615284) 1 NC_002971.3 hypothetical protein 615284 1208561 CBU_0672 Coxiella burnetii RSA 493 hypothetical protein NP_819702.1 613668 R 227377 CDS NP_819703.1 29654011 1208562 complement(615277..615822) 1 NC_002971.3 histidinol-phosphate phosphatase 615822 1208562 CBU_0673 Coxiella burnetii RSA 493 histidinol-phosphate phosphatase NP_819703.1 615277 R 227377 CDS NP_819704.2 215919016 1208563 complement(615816..616406) 1 NC_002971.3 SIS domain-containing protein 616406 1208563 CBU_0674 Coxiella burnetii RSA 493 SIS domain-containing protein NP_819704.2 615816 R 227377 CDS NP_819705.1 29654013 1208564 complement(616410..617153) 1 NC_002971.3 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 617153 1208564 CBU_0675 Coxiella burnetii RSA 493 translaldolase NP_819705.1 616410 R 227377 CDS NP_819706.1 29654014 1208565 617333..618346 1 NC_002971.3 UDP-glucose 4-epimerase 618346 1208565 CBU_0676 Coxiella burnetii RSA 493 UDP-glucose 4-epimerase NP_819706.1 617333 D 227377 CDS NP_819707.2 215919017 1208566 618343..619380 1 NC_002971.3 NAD dependent epimerase/dehydratase 619380 1208566 CBU_0677 Coxiella burnetii RSA 493 NAD dependent epimerase/dehydratase NP_819707.2 618343 D 227377 CDS NP_819708.1 29654016 1208567 619355..620935 1 NC_002971.3 ADP-heptose synthase 620935 1208567 CBU_0678 Coxiella burnetii RSA 493 ADP-heptose synthase NP_819708.1 619355 D 227377 CDS NP_819709.1 29654017 1208568 620938..621882 1 NC_002971.3 Gfo/Idh/MocA family oxidoreductase 621882 1208568 CBU_0679 Coxiella burnetii RSA 493 Gfo/Idh/MocA family oxidoreductase NP_819709.1 620938 D 227377 CDS NP_819710.1 29654018 1208569 621867..623177 1 NC_002971.3 UDP-glucose 6-dehydrogenase 623177 1208569 CBU_0680 Coxiella burnetii RSA 493 UDP-glucose 6-dehydrogenase NP_819710.1 621867 D 227377 CDS NP_819711.1 29654019 1208570 623170..624075 1 NC_002971.3 NAD-dependent epimerase/dehydratase 624075 1208570 CBU_0681 Coxiella burnetii RSA 493 NAD-dependent epimerase/dehydratase NP_819711.1 623170 D 227377 CDS NP_819712.1 29654020 1208571 624078..624731 1 NC_002971.3 methyltransferase 624731 1208571 CBU_0682 Coxiella burnetii RSA 493 methyltransferase NP_819712.1 624078 D 227377 CDS NP_819713.1 29654021 1208572 complement(624728..625990) 1 NC_002971.3 FkbM family methyltransferase 625990 1208572 CBU_0683 Coxiella burnetii RSA 493 FkbM family methyltransferase NP_819713.1 624728 R 227377 CDS NP_819714.1 29654022 1208573 626329..627747 1 NC_002971.3 sulfotransferase 627747 1208573 CBU_0684 Coxiella burnetii RSA 493 sulfotransferase NP_819714.1 626329 D 227377 CDS NP_819715.1 29654023 1208574 628192..631530 1 NC_002971.3 hypothetical protein 631530 1208574 CBU_0685 Coxiella burnetii RSA 493 hypothetical protein NP_819715.1 628192 D 227377 CDS NP_819716.2 215919018 1208575 631758..632468 1 NC_002971.3 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha/beta fusion protein 632468 1208575 CBU_0686 Coxiella burnetii RSA 493 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha/beta fusion protein NP_819716.2 631758 D 227377 CDS NP_819717.1 29654025 1208576 632485..634128 1 NC_002971.3 hypothetical protein 634128 1208576 CBU_0687 Coxiella burnetii RSA 493 hypothetical protein NP_819717.1 632485 D 227377 CDS NP_819718.1 29654026 1208577 634508..635506 1 NC_002971.3 GDP-L-fucose synthase 635506 wcaG 1208577 wcaG Coxiella burnetii RSA 493 GDP-L-fucose synthase NP_819718.1 634508 D 227377 CDS NP_819719.1 29654027 1208578 635499..636545 1 NC_002971.3 GDP-mannose 4,6-dehydratase 636545 gmd 1208578 gmd Coxiella burnetii RSA 493 GDP-mannose 4,6-dehydratase NP_819719.1 635499 D 227377 CDS NP_819720.2 215919019 1208579 636554..637411 1 NC_002971.3 polyprenyl-phosphate beta-D-mannosyltransferase 637411 1208579 CBU_0690 Coxiella burnetii RSA 493 polyprenyl-phosphate beta-D-mannosyltransferase NP_819720.2 636554 D 227377 CDS NP_819721.2 215919020 1208580 637404..638642 1 NC_002971.3 methyltransferase 638642 1208580 CBU_0691 Coxiella burnetii RSA 493 methyltransferase NP_819721.2 637404 D 227377 CDS NP_819722.1 29654030 1208581 complement(638663..639724) 1 NC_002971.3 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit beta 639724 1208581 CBU_0692 Coxiella burnetii RSA 493 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit beta NP_819722.1 638663 R 227377 CDS NP_819723.2 215919021 1208582 complement(639721..640770) 1 NC_002971.3 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha 640770 1208582 CBU_0693 Coxiella burnetii RSA 493 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha NP_819723.2 639721 R 227377 CDS NP_819724.1 29654032 1208583 complement(640897..642009) 1 NC_002971.3 glycosyltransferase 642009 1208583 CBU_0694 Coxiella burnetii RSA 493 glycosyltransferase NP_819724.1 640897 R 227377 CDS NP_819725.1 29654033 1208584 complement(642071..643447) 1 NC_002971.3 hypothetical protein 643447 1208584 CBU_0695 Coxiella burnetii RSA 493 hypothetical protein NP_819725.1 642071 R 227377 CDS NP_819726.2 215919022 1208585 complement(643440..644594) 1 NC_002971.3 DegT/DnrJ/EryC1/StrS aminotransferase 644594 1208585 CBU_0696 Coxiella burnetii RSA 493 DegT/DnrJ/EryC1/StrS aminotransferase NP_819726.2 643440 R 227377 CDS NP_819727.1 29654035 1208586 complement(644625..645785) 1 NC_002971.3 DegT/DnrJ/EryC1/StrS aminotransferase 645785 1208586 CBU_0697 Coxiella burnetii RSA 493 DegT/DnrJ/EryC1/StrS aminotransferase NP_819727.1 644625 R 227377 CDS NP_819728.1 29654036 1208587 complement(645808..646977) 1 NC_002971.3 hypothetical protein 646977 1208587 CBU_0698 Coxiella burnetii RSA 493 hypothetical protein NP_819728.1 645808 R 227377 CDS NP_819729.1 29654037 1208588 647180..648739 1 NC_002971.3 sulfotransferase 648739 1208588 CBU_0699 Coxiella burnetii RSA 493 sulfotransferase NP_819729.1 647180 D 227377 CDS NP_819730.2 215919023 1208589 complement(648775..650532) 1 NC_002971.3 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from Escherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 650532 1208589 CBU_0700 Coxiella burnetii RSA 493 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase NP_819730.2 648775 R 227377 CDS NP_819731.2 215919024 1208590 complement(650514..651347) 1 NC_002971.3 myo-inositol 1-(4-)phosphatase; 3'(2'),5'-bisphosphate nucleotidase 651347 cysQ-2 1208590 cysQ-2 Coxiella burnetii RSA 493 3'(2'),5'-bisphosphate nucleotidase NP_819731.2 650514 R 227377 CDS NP_819732.1 29654040 1208591 651484..652233 1 NC_002971.3 short chain dehydrogenase/reductase oxidoreductase 652233 1208591 CBU_0702 Coxiella burnetii RSA 493 short chain dehydrogenase/reductase oxidoreductase NP_819732.1 651484 D 227377 CDS NP_819733.1 29654041 1208592 652243..653106 1 NC_002971.3 lipopolysaccharide/O-antigen ABC transporter permease 653106 1208592 CBU_0703 Coxiella burnetii RSA 493 lipopolysaccharide/O-antigen ABC transporter permease NP_819733.1 652243 D 227377 CDS NP_819734.1 29654042 1208593 653116..653892 1 NC_002971.3 polysaccharide export ATP-binding protein 653892 rfbI 1208593 rfbI Coxiella burnetii RSA 493 polysaccharide export ATP-binding protein NP_819734.1 653116 D 227377 CDS NP_819735.1 29654043 1208595 complement(654604..654933) 1 NC_002971.3 hypothetical protein 654933 1208595 CBU_0705 Coxiella burnetii RSA 493 hypothetical protein NP_819735.1 654604 R 227377 CDS NP_819736.1 29654044 1208596 complement(654950..655660) 1 NC_002971.3 hypothetical protein 655660 1208596 CBU_0706 Coxiella burnetii RSA 493 hypothetical protein NP_819736.1 654950 R 227377 CDS NP_819737.1 29654045 1208597 complement(655774..656064) 1 NC_002971.3 permease 656064 1208597 CBU_0707 Coxiella burnetii RSA 493 permease NP_819737.1 655774 R 227377 CDS NP_819740.1 29654048 1208601 complement(657794..657937) 1 NC_002971.3 hypothetical protein 657937 1208601 CBU_0711 Coxiella burnetii RSA 493 hypothetical protein NP_819740.1 657794 R 227377 CDS NP_819741.1 29654049 1208602 complement(658929..659564) 1 NC_002971.3 GacA family DNA-binding response regulator 659564 gacA.1 1208602 gacA.1 Coxiella burnetii RSA 493 GacA family DNA-binding response regulator NP_819741.1 658929 R 227377 CDS NP_819742.2 215919025 1208603 complement(659623..660873) 1 NC_002971.3 phosphate transporter 660873 1208603 CBU_0713 Coxiella burnetii RSA 493 phosphate transporter NP_819742.2 659623 R 227377 CDS NP_819743.2 215919026 1208604 complement(660923..661333) 1 NC_002971.3 hypothetical protein 661333 1208604 CBU_0714 Coxiella burnetii RSA 493 hypothetical protein NP_819743.2 660923 R 227377 CDS NP_819744.1 29654052 1208605 661506..662498 1 NC_002971.3 IS30 family transposase 662498 1208605 CBU_0715 Coxiella burnetii RSA 493 IS30 family transposase NP_819744.1 661506 D 227377 CDS NP_819745.1 29654053 1208606 complement(662557..663477) 1 NC_002971.3 thioredoxin reductase 663477 1208606 CBU_0716 Coxiella burnetii RSA 493 thioredoxin reductase NP_819745.1 662557 R 227377 CDS NP_819746.1 29654054 1208608 665529..665813 1 NC_002971.3 hypothetical protein 665813 1208608 CBU_0718 Coxiella burnetii RSA 493 hypothetical protein NP_819746.1 665529 D 227377 CDS NP_819747.1 29654055 1208609 665810..666235 1 NC_002971.3 hypothetical protein 666235 1208609 CBU_0719 Coxiella burnetii RSA 493 hypothetical protein NP_819747.1 665810 D 227377 CDS NP_819748.1 29654056 1208610 complement(666291..667172) 1 NC_002971.3 agmatinase 667172 1208610 CBU_0720 Coxiella burnetii RSA 493 agmatinase NP_819748.1 666291 R 227377 CDS NP_819749.2 215919027 1208611 complement(667172..668233) 1 NC_002971.3 transforms a conserved lysine residue of initiation factor 5A into deoxyhypusine; deoxyhypusine synthase-like protein 668233 1208611 CBU_0721 Coxiella burnetii RSA 493 deoxyhypusine synthase-like protein NP_819749.2 667172 R 227377 CDS NP_819750.2 215919028 1208612 complement(668257..669459) 1 NC_002971.3 decarboxylase, pyridoxal-dependent 669459 1208612 CBU_0722 Coxiella burnetii RSA 493 decarboxylase, pyridoxal-dependent NP_819750.2 668257 R 227377 CDS NP_819752.1 29654060 1208614 complement(669705..670697) 1 NC_002971.3 IS30 family transposase 670697 1208614 CBU_0724 Coxiella burnetii RSA 493 IS30 family transposase NP_819752.1 669705 R 227377 CDS YP_002332974.1 215919029 7065982 complement(672005..672070) 1 NC_002971.3 hypothetical protein 672070 7065982 CBU_0724c Coxiella burnetii RSA 493 hypothetical protein YP_002332974.1 672005 R 227377 CDS NP_819753.1 29654061 1208617 672203..673336 1 NC_002971.3 ABC transporter permease 673336 1208617 CBU_0727 Coxiella burnetii RSA 493 ABC transporter permease NP_819753.1 672203 D 227377 CDS NP_819754.2 215919030 1208618 673333..674142 1 NC_002971.3 ABC transporter ATP-binding protein 674142 1208618 CBU_0728 Coxiella burnetii RSA 493 ABC transporter ATP-binding protein NP_819754.2 673333 D 227377 CDS NP_819755.1 29654063 1208619 674126..675052 1 NC_002971.3 ABC transporter substrate-binding protein 675052 1208619 CBU_0729 Coxiella burnetii RSA 493 ABC transporter substrate-binding protein NP_819755.1 674126 D 227377 CDS NP_819756.1 29654064 1208620 675055..675654 1 NC_002971.3 hypothetical protein 675654 1208620 CBU_0730 Coxiella burnetii RSA 493 hypothetical protein NP_819756.1 675055 D 227377 CDS NP_819757.2 215919031 1208621 complement(675651..676121) 1 NC_002971.3 hypothetical protein 676121 1208621 CBU_0731 Coxiella burnetii RSA 493 hypothetical protein NP_819757.2 675651 R 227377 CDS NP_819760.1 29654068 1208624 complement(677209..677433) 1 NC_002971.3 hypothetical protein 677433 1208624 CBU_0734 Coxiella burnetii RSA 493 hypothetical protein NP_819760.1 677209 R 227377 CDS NP_819761.1 29654069 1208625 677415..678263 1 NC_002971.3 uridine phosphorylase 678263 1208625 CBU_0735 Coxiella burnetii RSA 493 uridine phosphorylase NP_819761.1 677415 D 227377 CDS NP_819762.1 29654070 1208626 complement(678284..678937) 1 NC_002971.3 hypothetical protein 678937 1208626 CBU_0736 Coxiella burnetii RSA 493 hypothetical protein NP_819762.1 678284 R 227377 CDS NP_819763.1 29654071 1208628 679226..680554 1 NC_002971.3 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 680554 tig 1208628 tig Coxiella burnetii RSA 493 trigger factor NP_819763.1 679226 D 227377 CDS NP_819764.1 29654072 1208629 680564..681151 1 NC_002971.3 'hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates'; ATP-dependent Clp protease proteolytic subunit 681151 clpP 1208629 clpP Coxiella burnetii RSA 493 ATP-dependent Clp protease proteolytic subunit NP_819764.1 680564 D 227377 CDS NP_819765.1 29654073 1208630 681206..682474 1 NC_002971.3 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 682474 clpX 1208630 clpX Coxiella burnetii RSA 493 ATP-dependent protease ATP-binding subunit ClpX NP_819765.1 681206 D 227377 CDS NP_819766.1 29654074 1208631 682488..684941 1 NC_002971.3 ATP-dependent endopeptidase 684941 lon 1208631 lon Coxiella burnetii RSA 493 ATP-dependent endopeptidase NP_819766.1 682488 D 227377 CDS NP_819767.1 29654075 1208632 684950..686272 1 NC_002971.3 TldD/PmbA family protein 686272 pmbA 1208632 pmbA Coxiella burnetii RSA 493 TldD/PmbA family protein NP_819767.1 684950 D 227377 CDS NP_819768.1 29654076 1208633 686356..686502 1 NC_002971.3 hypothetical protein 686502 1208633 CBU_0742 Coxiella burnetii RSA 493 hypothetical protein NP_819768.1 686356 D 227377 CDS NP_819769.1 29654077 1208634 complement(686499..686768) 1 NC_002971.3 phosphocarrier protein HPr 686768 ptsH 1208634 ptsH Coxiella burnetii RSA 493 phosphocarrier protein HPr NP_819769.1 686499 R 227377 CDS NP_819770.1 29654078 1208635 complement(686749..687327) 1 NC_002971.3 HPr kinase/phosphorylase 687327 1208635 CBU_0744 Coxiella burnetii RSA 493 HPr kinase/phosphorylase NP_819770.1 686749 R 227377 CDS NP_819771.1 29654079 1208636 complement(687327..687617) 1 NC_002971.3 ribosome-associated factor Y 687617 1208636 CBU_0745 Coxiella burnetii RSA 493 ribosome-associated factor Y NP_819771.1 687327 R 227377 CDS NP_819772.1 29654080 1208637 complement(687716..688465) 1 NC_002971.3 LPS ABC transporter ATP-binding protein 688465 1208637 CBU_0746 Coxiella burnetii RSA 493 LPS ABC transporter ATP-binding protein NP_819772.1 687716 R 227377 CDS NP_819773.2 215919032 1208638 complement(688468..688896) 1 NC_002971.3 cell envelope biogenesis protein YhbN 688896 1208638 CBU_0747 Coxiella burnetii RSA 493 cell envelope biogenesis protein YhbN NP_819773.2 688468 R 227377 CDS NP_819774.1 29654082 1208639 complement(688946..689533) 1 NC_002971.3 hypothetical protein 689533 1208639 CBU_0748 Coxiella burnetii RSA 493 hypothetical protein NP_819774.1 688946 R 227377 CDS NP_819775.1 29654083 1208640 complement(689549..690046) 1 NC_002971.3 HAD superfamily hydrolase 690046 1208640 CBU_0749 Coxiella burnetii RSA 493 HAD superfamily hydrolase NP_819775.1 689549 R 227377 CDS NP_819776.1 29654084 1208641 complement(690048..691022) 1 NC_002971.3 arabinose-5-phosphate isomerase 691022 1208641 CBU_0750 Coxiella burnetii RSA 493 arabinose-5-phosphate isomerase NP_819776.1 690048 R 227377 CDS NP_819777.1 29654085 1208642 691173..692477 1 NC_002971.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 692477 murA 1208642 murA Coxiella burnetii RSA 493 UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_819777.1 691173 D 227377 CDS NP_819778.2 215919033 1208643 692468..693409 1 NC_002971.3 esterase 693409 1208643 CBU_0752 Coxiella burnetii RSA 493 esterase NP_819778.2 692468 D 227377 CDS YP_002332975.1 215919034 7065895 693440..693622 1 NC_002971.3 hypothetical protein 693622 7065895 CBU_0752a Coxiella burnetii RSA 493 hypothetical protein YP_002332975.1 693440 D 227377 CDS NP_819779.1 29654087 1208644 complement(693720..696788) 1 NC_002971.3 AcrB/AcrD/AcrF family transporter 696788 1208644 CBU_0753 Coxiella burnetii RSA 493 AcrB/AcrD/AcrF family transporter NP_819779.1 693720 R 227377 CDS NP_819780.1 29654088 1208645 complement(696836..697882) 1 NC_002971.3 RND family efflux transporter MFP subunit 697882 1208645 CBU_0754 Coxiella burnetii RSA 493 RND family efflux transporter MFP subunit NP_819780.1 696836 R 227377 CDS NP_819781.1 29654089 1208646 complement(697882..699237) 1 NC_002971.3 endopeptidase 699237 degP.2 1208646 degP.2 Coxiella burnetii RSA 493 endopeptidase NP_819781.1 697882 R 227377 CDS NP_819782.2 215919035 1208647 complement(699398..700036) 1 NC_002971.3 hypothetical protein 700036 1208647 CBU_0756 Coxiella burnetii RSA 493 hypothetical protein NP_819782.2 699398 R 227377 CDS YP_338280.2 215919036 1208648 complement(700077..701060) 1 NC_002971.3 ribosomal large subunit pseudouridine synthase D 701060 rluD 1208648 rluD Coxiella burnetii RSA 493 ribosomal large subunit pseudouridine synthase D YP_338280.2 700077 R 227377 CDS NP_819783.2 215919037 1208649 701120..701938 1 NC_002971.3 competence lipoprotein ComL 701938 1208649 CBU_0758 Coxiella burnetii RSA 493 competence lipoprotein ComL NP_819783.2 701120 D 227377 CDS NP_819784.1 29654092 1208651 complement(703172..703546) 1 NC_002971.3 response regulator receiver domain-containing protein 703546 gacS 1208651 gacS Coxiella burnetii RSA 493 response regulator receiver domain-containing protein NP_819784.1 703172 R 227377 CDS NP_819785.1 29654093 1208652 703762..703872 1 NC_002971.3 hypothetical protein 703872 1208652 CBU_0761 Coxiella burnetii RSA 493 hypothetical protein NP_819785.1 703762 D 227377 CDS NP_819786.1 29654094 1208653 703865..704491 1 NC_002971.3 hypothetical protein 704491 1208653 CBU_0762 Coxiella burnetii RSA 493 hypothetical protein NP_819786.1 703865 D 227377 CDS NP_819787.2 215919038 1208654 704512..705102 1 NC_002971.3 hypothetical protein 705102 1208654 CBU_0763 Coxiella burnetii RSA 493 hypothetical protein NP_819787.2 704512 D 227377 CDS NP_819788.1 29654096 1208657 complement(709333..711285) 1 NC_002971.3 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 711285 1208657 CBU_0766 Coxiella burnetii RSA 493 acetoacetyl-CoA synthetase NP_819788.1 709333 R 227377 CDS NP_819789.1 29654097 1208659 711583..711714 1 NC_002971.3 hypothetical protein 711714 1208659 CBU_0767 Coxiella burnetii RSA 493 hypothetical protein NP_819789.1 711583 D 227377 CDS NP_819790.2 215919039 1208660 712126..713661 1 NC_002971.3 multidrug resistance protein B 713661 1208660 CBU_0768 Coxiella burnetii RSA 493 multidrug resistance protein B NP_819790.2 712126 D 227377 CDS NP_819791.1 29654099 1208661 713761..714447 1 NC_002971.3 glutamine-hydrolyzing; GMP synthase 714447 1208661 CBU_0769 Coxiella burnetii RSA 493 GMP synthase NP_819791.1 713761 D 227377 CDS NP_819792.2 215919040 1208662 714614..715879 1 NC_002971.3 ATPase 715879 1208662 CBU_0770 Coxiella burnetii RSA 493 ATPase NP_819792.2 714614 D 227377 CDS NP_819793.1 29654101 1208663 716051..716923 1 NC_002971.3 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 716923 prpB 1208663 prpB Coxiella burnetii RSA 493 2-methylisocitrate lyase NP_819793.1 716051 D 227377 CDS NP_819794.1 29654102 1208664 716916..718034 1 NC_002971.3 2-methylcitrate synthase 718034 prpC 1208664 prpC Coxiella burnetii RSA 493 2-methylcitrate synthase NP_819794.1 716916 D 227377 CDS NP_819795.1 29654103 1208665 718037..718507 1 NC_002971.3 glyoxalase 718507 phnB 1208665 phnB Coxiella burnetii RSA 493 glyoxalase NP_819795.1 718037 D 227377 CDS NP_819796.1 29654104 1208666 718636..718884 1 NC_002971.3 PspC domain-containing protein 718884 pspC 1208666 pspC Coxiella burnetii RSA 493 PspC domain-containing protein NP_819796.1 718636 D 227377 CDS NP_819797.1 29654105 1208667 718891..719232 1 NC_002971.3 GntR family transcriptional regulator 719232 1208667 CBU_0775 Coxiella burnetii RSA 493 GntR family transcriptional regulator NP_819797.1 718891 D 227377 CDS NP_819798.1 29654106 1208668 719229..720080 1 NC_002971.3 ABC transporter ATP-binding protein 720080 1208668 CBU_0776 Coxiella burnetii RSA 493 ABC transporter ATP-binding protein NP_819798.1 719229 D 227377 CDS NP_819799.2 215919041 1208669 720077..720991 1 NC_002971.3 ABC transporter permease 720991 1208669 CBU_0777 Coxiella burnetii RSA 493 ABC transporter permease NP_819799.2 720077 D 227377 CDS YP_002332976.1 215919042 7065891 complement(721562..721960) 1 NC_002971.3 hypothetical protein 721960 7065891 CBU_0777c Coxiella burnetii RSA 493 hypothetical protein YP_002332976.1 721562 R 227377 CDS NP_819801.1 29654109 1208672 722166..722816 1 NC_002971.3 LuxR family transcriptional regulator 722816 gacA.2 1208672 gacA.2 Coxiella burnetii RSA 493 LuxR family transcriptional regulator NP_819801.1 722166 D 227377 CDS NP_819802.1 29654110 1208673 722881..723897 1 NC_002971.3 ankyrin repeat-containing protein 723897 1208673 CBU_0781 Coxiella burnetii RSA 493 ankyrin repeat-containing protein NP_819802.1 722881 D 227377 CDS NP_819803.1 29654111 1208674 724097..725485 1 NC_002971.3 hypothetical protein 725485 1208674 CBU_0782 Coxiella burnetii RSA 493 hypothetical protein NP_819803.1 724097 D 227377 CDS NP_819804.1 29654112 1208676 726619..726726 1 NC_002971.3 hypothetical protein 726726 1208676 CBU_0784 Coxiella burnetii RSA 493 hypothetical protein NP_819804.1 726619 D 227377 CDS NP_819806.2 215919043 1208678 726996..728168 1 NC_002971.3 coA-transferase III protein 728168 1208678 CBU_0786 Coxiella burnetii RSA 493 coA-transferase III protein NP_819806.2 726996 D 227377 CDS NP_819807.2 215919044 1208679 728202..729746 1 NC_002971.3 AMP-binding protein 729746 1208679 CBU_0787 Coxiella burnetii RSA 493 AMP-binding protein NP_819807.2 728202 D 227377 CDS NP_819808.1 29654116 1208680 729736..734574 1 NC_002971.3 polyketide synthase 734574 1208680 CBU_0788 Coxiella burnetii RSA 493 polyketide synthase NP_819808.1 729736 D 227377 CDS NP_819809.2 215919045 1208681 734690..737185 1 NC_002971.3 two component system histidine kinase 737185 1208681 CBU_0789 Coxiella burnetii RSA 493 two component system histidine kinase NP_819809.2 734690 D 227377 CDS NP_819812.2 215919046 1208684 740711..742099 1 NC_002971.3 multidrug resistance protein B 742099 1208684 CBU_0792 Coxiella burnetii RSA 493 multidrug resistance protein B NP_819812.2 740711 D 227377 CDS NP_819813.1 29654121 1208685 complement(742203..742817) 1 NC_002971.3 hypothetical protein 742817 1208685 CBU_0793 Coxiella burnetii RSA 493 hypothetical protein NP_819813.1 742203 R 227377 CDS NP_819814.1 29654122 1208686 complement(742864..744258) 1 NC_002971.3 hypothetical protein 744258 1208686 CBU_0794 Coxiella burnetii RSA 493 hypothetical protein NP_819814.1 742864 R 227377 CDS NP_819815.2 215919047 1208688 complement(744694..745260) 1 NC_002971.3 'involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer'; GTP cyclohydrolase I 745260 folE 1208688 folE Coxiella burnetii RSA 493 GTP cyclohydrolase I NP_819815.2 744694 R 227377 CDS NP_819816.1 29654124 1208689 complement(745260..745601) 1 NC_002971.3 histidine triad domain protein 745601 1208689 CBU_0796 Coxiella burnetii RSA 493 histidine triad domain protein NP_819816.1 745260 R 227377 CDS NP_819817.1 29654125 1208690 complement(745618..747198) 1 NC_002971.3 EmrB/QacA family drug resistance transporter 747198 1208690 CBU_0797 Coxiella burnetii RSA 493 EmrB/QacA family drug resistance transporter NP_819817.1 745618 R 227377 CDS NP_819818.1 29654126 1208691 complement(747199..748194) 1 NC_002971.3 multidrug resistance protein A 748194 1208691 CBU_0798 Coxiella burnetii RSA 493 multidrug resistance protein A NP_819818.1 747199 R 227377 CDS NP_819819.1 29654127 1208692 748218..748343 1 NC_002971.3 hypothetical protein 748343 1208692 CBU_0799 Coxiella burnetii RSA 493 hypothetical protein NP_819819.1 748218 D 227377 CDS NP_819820.1 29654128 1208693 748340..748753 1 NC_002971.3 hypothetical protein 748753 1208693 CBU_0800 Coxiella burnetii RSA 493 hypothetical protein NP_819820.1 748340 D 227377 CDS NP_819821.1 29654129 1208694 748750..749187 1 NC_002971.3 ribosomal-protein-S18-alanine acetyltransferase 749187 rimI 1208694 rimI Coxiella burnetii RSA 493 ribosomal-protein-S18-alanine acetyltransferase NP_819821.1 748750 D 227377 CDS NP_819822.2 215919048 1208695 complement(749208..750014) 1 NC_002971.3 hypothetical protein 750014 1208695 CBU_0802 Coxiella burnetii RSA 493 hypothetical protein NP_819822.2 749208 R 227377 CDS NP_819823.1 29654131 1208696 750192..751247 1 NC_002971.3 RND family efflux transporter MFP subunit 751247 1208696 CBU_0803 Coxiella burnetii RSA 493 RND family efflux transporter MFP subunit NP_819823.1 750192 D 227377 CDS NP_819824.1 29654132 1208697 751255..754293 1 NC_002971.3 AcrB/AcrD/AcrF family transporter 754293 1208697 CBU_0804 Coxiella burnetii RSA 493 AcrB/AcrD/AcrF family transporter NP_819824.1 751255 D 227377 CDS NP_819825.2 215919049 1208698 complement(754657..754767) 1 NC_002971.3 hypothetical protein 754767 1208698 CBU_0805 Coxiella burnetii RSA 493 hypothetical protein NP_819825.2 754657 R 227377 CDS NP_819826.1 29654134 1208699 complement(754871..754978) 1 NC_002971.3 hypothetical protein 754978 1208699 CBU_0806 Coxiella burnetii RSA 493 hypothetical protein NP_819826.1 754871 R 227377 CDS NP_819827.1 29654135 1208700 755036..756175 1 NC_002971.3 beta-lactamase 756175 1208700 CBU_0807 Coxiella burnetii RSA 493 beta-lactamase NP_819827.1 755036 D 227377 CDS NP_819828.1 29654136 1208701 complement(756207..758969) 1 NC_002971.3 valyl-tRNA synthetase 758969 valS 1208701 valS Coxiella burnetii RSA 493 valyl-tRNA synthetase NP_819828.1 756207 R 227377 CDS NP_819829.2 215919050 1208702 759106..760224 1 NC_002971.3 permease 760224 1208702 CBU_0809 Coxiella burnetii RSA 493 permease NP_819829.2 759106 D 227377 CDS NP_819830.1 29654138 1208703 760212..761279 1 NC_002971.3 permease 761279 1208703 CBU_0810 Coxiella burnetii RSA 493 permease NP_819830.1 760212 D 227377 CDS NP_819831.1 29654139 1208704 761280..762857 1 NC_002971.3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 762857 prfC 1208704 prfC Coxiella burnetii RSA 493 peptide chain release factor 3 NP_819831.1 761280 D 227377 CDS NP_819832.1 29654140 1208705 762872..764230 1 NC_002971.3 Na+ driven multidrug efflux pump 764230 1208705 CBU_0812 Coxiella burnetii RSA 493 Na+ driven multidrug efflux pump NP_819832.1 762872 D 227377 CDS NP_819833.1 29654141 1208706 764518..764976 1 NC_002971.3 hypothetical protein 764976 1208706 CBU_0813 Coxiella burnetii RSA 493 hypothetical protein NP_819833.1 764518 D 227377 CDS NP_819837.2 215919051 1208710 complement(767242..767844) 1 NC_002971.3 GNAT family acetyltransferase 767844 aacA4 1208710 aacA4 Coxiella burnetii RSA 493 GNAT family acetyltransferase NP_819837.2 767242 R 227377 CDS NP_819838.1 29654146 1208711 768058..768639 1 NC_002971.3 TetR family transcriptional regulator 768639 1208711 CBU_0818 Coxiella burnetii RSA 493 TetR family transcriptional regulator NP_819838.1 768058 D 227377 CDS NP_819839.1 29654147 1208712 768696..769370 1 NC_002971.3 glutathione S-transferase 769370 1208712 CBU_0819 Coxiella burnetii RSA 493 glutathione S-transferase NP_819839.1 768696 D 227377 CDS NP_819842.1 29654150 1208715 complement(770839..771975) 1 NC_002971.3 Fic family protein 771975 1208715 CBU_0822 Coxiella burnetii RSA 493 Fic family protein NP_819842.1 770839 R 227377 CDS NP_819843.1 29654151 1208716 complement(772421..774118) 1 NC_002971.3 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 774118 sfcA 1208716 sfcA Coxiella burnetii RSA 493 malate dehydrogenase NP_819843.1 772421 R 227377 CDS NP_819844.1 29654152 1208717 complement(774146..775531) 1 NC_002971.3 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 775531 purB 1208717 purB Coxiella burnetii RSA 493 adenylosuccinate lyase NP_819844.1 774146 R 227377 CDS NP_819845.1 29654153 1208718 775635..776744 1 NC_002971.3 DegT/DnrJ/EryC1/StrS aminotransferase 776744 1208718 CBU_0825 Coxiella burnetii RSA 493 DegT/DnrJ/EryC1/StrS aminotransferase NP_819845.1 775635 D 227377 CDS NP_819846.1 29654154 1208719 776731..777234 1 NC_002971.3 transcriptional activator RfaH 777234 rfaH 1208719 rfaH Coxiella burnetii RSA 493 transcriptional activator RfaH NP_819846.1 776731 D 227377 CDS NP_819847.1 29654155 1208720 777269..777865 1 NC_002971.3 hypothetical protein 777865 1208720 CBU_0827 Coxiella burnetii RSA 493 hypothetical protein NP_819847.1 777269 D 227377 CDS NP_819848.1 29654156 1208721 777942..779495 1 NC_002971.3 hexapeptide repeat-containing oxidoreductase 779495 1208721 CBU_0828 Coxiella burnetii RSA 493 hexapeptide repeat-containing oxidoreductase NP_819848.1 777942 D 227377 CDS NP_819849.2 215919052 1208722 779510..780505 1 NC_002971.3 NAD dependent epimerase/dehydratase 780505 1208722 CBU_0829 Coxiella burnetii RSA 493 NAD dependent epimerase/dehydratase NP_819849.2 779510 D 227377 CDS NP_819850.1 29654158 1208723 780502..781656 1 NC_002971.3 perosamine synthetase 781656 1208723 CBU_0830 Coxiella burnetii RSA 493 perosamine synthetase NP_819850.1 780502 D 227377 CDS NP_819851.1 29654159 1208724 781659..783557 1 NC_002971.3 glutamine-hydrolyzing; asparagine synthetase 783557 asnB-1 1208724 asnB-1 Coxiella burnetii RSA 493 asparagine synthetase NP_819851.1 781659 D 227377 CDS NP_819852.1 29654160 1208725 783558..784109 1 NC_002971.3 acetyltransferase 784109 1208725 CBU_0832 Coxiella burnetii RSA 493 acetyltransferase NP_819852.1 783558 D 227377 CDS NP_819853.1 29654161 1208726 784120..785925 1 NC_002971.3 ABC transporter permease/ATP-binding protein 785925 1208726 CBU_0833 Coxiella burnetii RSA 493 ABC transporter permease/ATP-binding protein NP_819853.1 784120 D 227377 CDS NP_819854.1 29654162 1208727 785938..786924 1 NC_002971.3 methyltransferase 786924 1208727 CBU_0834 Coxiella burnetii RSA 493 methyltransferase NP_819854.1 785938 D 227377 CDS NP_819855.1 29654163 1208728 786933..787202 1 NC_002971.3 hypothetical protein 787202 1208728 CBU_0835 Coxiella burnetii RSA 493 hypothetical protein NP_819855.1 786933 D 227377 CDS NP_819856.2 215919053 1208729 787206..788282 1 NC_002971.3 radical SAM domain-containing protein 788282 1208729 CBU_0836 Coxiella burnetii RSA 493 radical SAM domain-containing protein NP_819856.2 787206 D 227377 CDS NP_819857.1 29654165 1208730 788297..789781 1 NC_002971.3 hypothetical protein 789781 1208730 CBU_0837 Coxiella burnetii RSA 493 hypothetical protein NP_819857.1 788297 D 227377 CDS NP_819858.2 215919054 1208731 790067..791167 1 NC_002971.3 lipopolysaccharide N-acetylglucosaminyltransferase 791167 1208731 CBU_0838 Coxiella burnetii RSA 493 lipopolysaccharide N-acetylglucosaminyltransferase NP_819858.2 790067 D 227377 CDS NP_819859.1 29654167 1208732 791303..792595 1 NC_002971.3 glycosyltransferase 792595 1208732 CBU_0839 Coxiella burnetii RSA 493 glycosyltransferase NP_819859.1 791303 D 227377 CDS NP_819860.1 29654168 1208733 792595..794508 1 NC_002971.3 asparagine synthase 794508 asnB-2 1208733 asnB-2 Coxiella burnetii RSA 493 asparagine synthase NP_819860.1 792595 D 227377 CDS NP_819861.1 29654169 1208734 794515..795648 1 NC_002971.3 alpha-D-QuiNAc alpha-1,3-galactosyltransferase 795648 1208734 CBU_0841 Coxiella burnetii RSA 493 alpha-D-QuiNAc alpha-1,3-galactosyltransferase NP_819861.1 794515 D 227377 CDS NP_819862.1 29654170 1208735 795879..796976 1 NC_002971.3 UDP-N-acetylglucosamine 2-epimerase 796976 wecB 1208735 wecB Coxiella burnetii RSA 493 UDP-N-acetylglucosamine 2-epimerase NP_819862.1 795879 D 227377 CDS NP_819863.2 215919055 1208736 796987..798144 1 NC_002971.3 glycosyltransferase 798144 1208736 CBU_0843 Coxiella burnetii RSA 493 glycosyltransferase NP_819863.2 796987 D 227377 CDS NP_819864.2 215919056 1208737 complement(798149..799168) 1 NC_002971.3 capsular polysaccharide biosynthesis protein 799168 1208737 CBU_0844 Coxiella burnetii RSA 493 capsular polysaccharide biosynthesis protein NP_819864.2 798149 R 227377 CDS NP_819865.1 29654173 1208738 complement(799156..800445) 1 NC_002971.3 UDP-glucose/GDP-mannose dehydrogenase 800445 1208738 CBU_0845 Coxiella burnetii RSA 493 UDP-glucose/GDP-mannose dehydrogenase NP_819865.1 799156 R 227377 CDS NP_819866.1 29654174 1208739 800503..801852 1 NC_002971.3 UDP-glucose 6-dehydrogenase 801852 ugd 1208739 ugd Coxiella burnetii RSA 493 UDP-glucose 6-dehydrogenase NP_819866.1 800503 D 227377 CDS NP_819867.1 29654175 1208740 801866..802630 1 NC_002971.3 oxidoreductase, short chain dehydrogenase/reductase 802630 1208740 CBU_0847 Coxiella burnetii RSA 493 oxidoreductase, short chain dehydrogenase/reductase NP_819867.1 801866 D 227377 CDS NP_819868.1 29654176 1208741 802640..804283 1 NC_002971.3 glucose-6-phosphate isomerase; glucose-6 phosphate 1-epimerase 804283 pgi 1208741 pgi Coxiella burnetii RSA 493 glucose-6 phosphate 1-epimerase NP_819868.1 802640 D 227377 CDS NP_819869.1 29654177 1208742 804280..805167 1 NC_002971.3 UTP-glucose-1-phosphate uridylyltransferase 805167 galU 1208742 galU Coxiella burnetii RSA 493 UTP-glucose-1-phosphate uridylyltransferase NP_819869.1 804280 D 227377 CDS NP_819870.2 215919057 1208743 805231..806124 1 NC_002971.3 hypothetical protein 806124 1208743 CBU_0850 Coxiella burnetii RSA 493 hypothetical protein NP_819870.2 805231 D 227377 CDS NP_819871.1 29654179 1208744 806380..806649 1 NC_002971.3 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 806649 rpsO 1208744 rpsO Coxiella burnetii RSA 493 30S ribosomal protein S15 NP_819871.1 806380 D 227377 CDS NP_819872.1 29654180 1208745 806660..808750 1 NC_002971.3 polynucleotide phosphorylase 808750 pnp 1208745 pnp Coxiella burnetii RSA 493 polynucleotide phosphorylase NP_819872.1 806660 D 227377 CDS NP_819873.2 215919058 1208746 complement(808842..809318) 1 NC_002971.3 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 809318 mgsA 1208746 mgsA Coxiella burnetii RSA 493 methylglyoxal synthase NP_819873.2 808842 R 227377 CDS NP_819874.1 29654182 1208747 809343..809453 1 NC_002971.3 hypothetical protein 809453 1208747 CBU_0854 Coxiella burnetii RSA 493 hypothetical protein NP_819874.1 809343 D 227377 CDS NP_819875.2 215919059 1208749 811791..813581 1 NC_002971.3 lipid ABC transporter permease/ATP-binding protein 813581 1208749 CBU_0856 Coxiella burnetii RSA 493 lipid ABC transporter permease/ATP-binding protein NP_819875.2 811791 D 227377 CDS NP_819876.1 29654184 1208750 813581..814558 1 NC_002971.3 'transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate'; tetraacyldisaccharide 4'-kinase 814558 lpxK 1208750 lpxK Coxiella burnetii RSA 493 tetraacyldisaccharide 4'-kinase NP_819876.1 813581 D 227377 CDS NP_819877.1 29654185 1208751 complement(814555..816183) 1 NC_002971.3 glutamine-dependent NAD(+) synthetase 816183 nadE 1208751 nadE Coxiella burnetii RSA 493 glutamine-dependent NAD(+) synthetase NP_819877.1 814555 R 227377 CDS NP_819878.1 29654186 1208752 complement(816190..816561) 1 NC_002971.3 hypothetical protein 816561 1208752 CBU_0859 Coxiella burnetii RSA 493 hypothetical protein NP_819878.1 816190 R 227377 CDS NP_819879.2 215919060 1208753 816685..817146 1 NC_002971.3 hypothetical protein 817146 1208753 CBU_0860 Coxiella burnetii RSA 493 hypothetical protein NP_819879.2 816685 D 227377 CDS NP_819882.1 29654190 1208756 819088..819198 1 NC_002971.3 hypothetical protein 819198 1208756 CBU_0863 Coxiella burnetii RSA 493 hypothetical protein NP_819882.1 819088 D 227377 CDS NP_819883.1 29654191 1208757 819185..819568 1 NC_002971.3 'binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21'; 30S ribosomal protein S6 819568 rpsF 1208757 rpsF Coxiella burnetii RSA 493 30S ribosomal protein S6 NP_819883.1 819185 D 227377 CDS NP_819884.1 29654192 1208758 819581..819802 1 NC_002971.3 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 819802 rpsR 1208758 rpsR Coxiella burnetii RSA 493 30S ribosomal protein S18 NP_819884.1 819581 D 227377 CDS NP_819885.1 29654193 1208759 819806..820705 1 NC_002971.3 hypothetical protein 820705 1208759 CBU_0866 Coxiella burnetii RSA 493 hypothetical protein NP_819885.1 819806 D 227377 CDS NP_819886.2 215919061 1208760 820717..821181 1 NC_002971.3 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 821181 rplI 1208760 rplI Coxiella burnetii RSA 493 50S ribosomal protein L9 NP_819886.2 820717 D 227377 CDS NP_819887.1 29654195 1208761 821430..823262 1 NC_002971.3 replicative DNA helicase 823262 dnaB 1208761 dnaB Coxiella burnetii RSA 493 replicative DNA helicase NP_819887.1 821430 D 227377 CDS NP_819888.1 29654196 1208762 823259..824353 1 NC_002971.3 alanine racemase 824353 alr 1208762 alr Coxiella burnetii RSA 493 alanine racemase NP_819888.1 823259 D 227377 CDS NP_819889.1 29654197 1208763 824350..824598 1 NC_002971.3 hypothetical protein 824598 1208763 CBU_0870 Coxiella burnetii RSA 493 hypothetical protein NP_819889.1 824350 D 227377 CDS NP_819890.1 29654198 1208765 complement(825124..825771) 1 NC_002971.3 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 825771 udk 1208765 udk Coxiella burnetii RSA 493 uridine kinase NP_819890.1 825124 R 227377 CDS NP_819891.1 29654199 1208766 complement(825761..826360) 1 NC_002971.3 Smr domain-containing protein 826360 1208766 CBU_0873 Coxiella burnetii RSA 493 Smr domain-containing protein NP_819891.1 825761 R 227377 CDS NP_819892.1 29654200 1208767 826483..827541 1 NC_002971.3 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 827541 aroC 1208767 aroC Coxiella burnetii RSA 493 chorismate synthase NP_819892.1 826483 D 227377 CDS NP_819893.1 29654201 1208768 827554..828576 1 NC_002971.3 aspartate-semialdehyde dehydrogenase 828576 asd 1208768 asd Coxiella burnetii RSA 493 aspartate-semialdehyde dehydrogenase NP_819893.1 827554 D 227377 CDS NP_819894.1 29654202 1208769 complement(828841..829947) 1 NC_002971.3 thiazole biosynthesis adenylyltransferase ThiF 829947 1208769 CBU_0876 Coxiella burnetii RSA 493 thiazole biosynthesis adenylyltransferase ThiF NP_819894.1 828841 R 227377 CDS NP_819895.1 29654203 1208770 830133..830249 1 NC_002971.3 hypothetical protein 830249 1208770 CBU_0877 Coxiella burnetii RSA 493 hypothetical protein NP_819895.1 830133 D 227377 CDS NP_819898.2 215919062 1208773 831421..832806 1 NC_002971.3 hypothetical protein 832806 1208773 CBU_0880 Coxiella burnetii RSA 493 hypothetical protein NP_819898.2 831421 D 227377 CDS NP_819899.1 29654207 1208774 complement(833049..833714) 1 NC_002971.3 hypothetical protein 833714 1208774 CBU_0881 Coxiella burnetii RSA 493 hypothetical protein NP_819899.1 833049 R 227377 CDS NP_819900.1 29654208 1208776 complement(835121..835255) 1 NC_002971.3 hypothetical protein 835255 1208776 CBU_0883 Coxiella burnetii RSA 493 hypothetical protein NP_819900.1 835121 R 227377 CDS NP_819901.1 29654209 1208777 835524..837332 1 NC_002971.3 GTP-binding protein TypA 837332 bipA 1208777 bipA Coxiella burnetii RSA 493 GTP-binding protein TypA NP_819901.1 835524 D 227377 CDS NP_819902.2 215919063 1208778 837344..838510 1 NC_002971.3 hypothetical protein 838510 1208778 CBU_0885 Coxiella burnetii RSA 493 hypothetical protein NP_819902.2 837344 D 227377 CDS NP_819903.1 29654211 1208779 838542..839717 1 NC_002971.3 phosphopantothenoylcysteine decarboxylase; phosphopantothenate--cysteine ligase 839717 coaBC 1208779 coaBC Coxiella burnetii RSA 493 phosphopantothenate--cysteine ligase NP_819903.1 838542 D 227377 CDS NP_819904.1 29654212 1208781 complement(840887..841330) 1 NC_002971.3 DsbB family disulfide bond formation protein 841330 1208781 CBU_0888 Coxiella burnetii RSA 493 DsbB family disulfide bond formation protein NP_819904.1 840887 R 227377 CDS NP_819905.2 215919064 1208782 complement(841327..841926) 1 NC_002971.3 disulfide bond formation protein D 841926 dsbA 1208782 dsbA Coxiella burnetii RSA 493 disulfide bond formation protein D NP_819905.2 841327 R 227377 CDS NP_819906.1 29654214 1208783 complement(841965..842666) 1 NC_002971.3 Zn-dependent hydrolase, glyoxalase II family 842666 1208783 CBU_0890 Coxiella burnetii RSA 493 Zn-dependent hydrolase, glyoxalase II family NP_819906.1 841965 R 227377 CDS NP_819907.1 29654215 1208784 842764..843702 1 NC_002971.3 hypothetical protein 843702 1208784 CBU_0891 Coxiella burnetii RSA 493 hypothetical protein NP_819907.1 842764 D 227377 CDS YP_338281.1 77358715 1208785 843707..844492 1 NC_002971.3 'mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability'; tRNA pseudouridine synthase A 844492 truA 1208785 truA Coxiella burnetii RSA 493 tRNA pseudouridine synthase A YP_338281.1 843707 D 227377 CDS NP_819908.1 29654216 1208786 844523..845398 1 NC_002971.3 acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 845398 accD 1208786 accD Coxiella burnetii RSA 493 acetyl-coenzyme A carboxylase carboxyl transferase subunit beta NP_819908.1 844523 D 227377 CDS NP_819909.1 29654217 1208787 845531..846781 1 NC_002971.3 folylpolyglutamate synthase; dihydrofolate synthase 846781 folC 1208787 folC Coxiella burnetii RSA 493 dihydrofolate synthase NP_819909.1 845531 D 227377 CDS NP_819910.2 215919065 1208788 846765..847382 1 NC_002971.3 sporulation and cell division repeat protein 847382 dedD 1208788 dedD Coxiella burnetii RSA 493 sporulation and cell division repeat protein NP_819910.2 846765 D 227377 CDS NP_819911.1 29654219 1208789 847450..848004 1 NC_002971.3 colicin V production protein 848004 dedE 1208789 dedE Coxiella burnetii RSA 493 colicin V production protein NP_819911.1 847450 D 227377 CDS NP_819912.1 29654220 1208790 848013..849533 1 NC_002971.3 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 849533 purF 1208790 purF Coxiella burnetii RSA 493 amidophosphoribosyltransferase NP_819912.1 848013 D 227377 CDS NP_819913.1 29654221 1208791 849530..849862 1 NC_002971.3 thyroglobulin type-1 repeat-containing protein 849862 1208791 CBU_0898 Coxiella burnetii RSA 493 thyroglobulin type-1 repeat-containing protein NP_819913.1 849530 D 227377 CDS NP_819915.1 29654223 1208793 850442..850606 1 NC_002971.3 hypothetical protein 850606 1208793 CBU_0900 Coxiella burnetii RSA 493 hypothetical protein NP_819915.1 850442 D 227377 CDS NP_819919.1 29654227 1208797 854566..855627 1 NC_002971.3 tRNA-dihydrouridine synthase A 855627 1208797 CBU_0904 Coxiella burnetii RSA 493 tRNA-dihydrouridine synthase A NP_819919.1 854566 D 227377 CDS NP_819920.1 29654228 1208798 complement(855639..855878) 1 NC_002971.3 'RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome'; 50S ribosomal protein L31 855878 rpmE 1208798 rpmE Coxiella burnetii RSA 493 50S ribosomal protein L31 NP_819920.1 855639 R 227377 CDS NP_819921.1 29654229 1208799 855998..857296 1 NC_002971.3 MFS superfamily transporter 857296 1208799 CBU_0906 Coxiella burnetii RSA 493 MFS superfamily transporter NP_819921.1 855998 D 227377 CDS NP_819922.1 29654230 1208800 complement(857314..857892) 1 NC_002971.3 YciL; protein; BolA 857892 yciL 1208800 yciL Coxiella burnetii RSA 493 BolA NP_819922.1 857314 R 227377 CDS NP_819923.1 29654231 1208801 complement(857895..858440) 1 NC_002971.3 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 858440 ispZ 1208801 ispZ Coxiella burnetii RSA 493 intracellular septation protein A NP_819923.1 857895 R 227377 CDS NP_819924.1 29654232 1208802 858493..859107 1 NC_002971.3 sua5/YciO/YrdC/YwlC family protein 859107 1208802 CBU_0909 Coxiella burnetii RSA 493 sua5/YciO/YrdC/YwlC family protein NP_819924.1 858493 D 227377 CDS NP_819925.1 29654233 1208803 859205..860179 1 NC_002971.3 hypothetical protein 860179 1208803 CBU_0910 Coxiella burnetii RSA 493 hypothetical protein NP_819925.1 859205 D 227377 CDS NP_819926.2 215919066 1208804 complement(860182..860325) 1 NC_002971.3 hypothetical protein 860325 1208804 CBU_0911 Coxiella burnetii RSA 493 hypothetical protein NP_819926.2 860182 R 227377 CDS NP_819927.1 29654235 1208805 complement(860619..862043) 1 NC_002971.3 'functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C'; 2-methylcitrate dehydratase 862043 prpD 1208805 prpD Coxiella burnetii RSA 493 2-methylcitrate dehydratase NP_819927.1 860619 R 227377 CDS NP_819928.1 29654236 1208806 complement(862045..862518) 1 NC_002971.3 thioesterase 862518 1208806 CBU_0913 Coxiella burnetii RSA 493 thioesterase NP_819928.1 862045 R 227377 CDS NP_819929.1 29654237 1208807 complement(862757..863872) 1 NC_002971.3 hypothetical protein 863872 1208807 CBU_0914 Coxiella burnetii RSA 493 hypothetical protein NP_819929.1 862757 R 227377 CDS NP_819930.1 29654238 1208808 complement(863874..864383) 1 NC_002971.3 enhanced entry protein 864383 enhB.1 1208808 enhB.1 Coxiella burnetii RSA 493 enhanced entry protein NP_819930.1 863874 R 227377 CDS NP_819931.1 29654239 1208809 864577..865344 1 NC_002971.3 hypothetical protein 865344 1208809 CBU_0916 Coxiella burnetii RSA 493 hypothetical protein NP_819931.1 864577 D 227377 CDS NP_819932.1 29654240 1208811 866870..868639 1 NC_002971.3 hypothetical protein 868639 1208811 CBU_0918 Coxiella burnetii RSA 493 hypothetical protein NP_819932.1 866870 D 227377 CDS NP_819933.1 29654241 1208813 870210..871325 1 NC_002971.3 fatty acid desaturase 871325 1208813 CBU_0920 Coxiella burnetii RSA 493 fatty acid desaturase NP_819933.1 870210 D 227377 CDS NP_819934.1 29654242 1208814 871356..871670 1 NC_002971.3 hypothetical protein 871670 1208814 CBU_0921 Coxiella burnetii RSA 493 hypothetical protein NP_819934.1 871356 D 227377 CDS NP_819935.1 29654243 1208815 complement(871618..872931) 1 NC_002971.3 MFS superfamily transporter 872931 1208815 CBU_0922 Coxiella burnetii RSA 493 MFS superfamily transporter NP_819935.1 871618 R 227377 CDS NP_819936.1 29654244 1208816 873052..874182 1 NC_002971.3 hypothetical protein 874182 1208816 CBU_0923 Coxiella burnetii RSA 493 hypothetical protein NP_819936.1 873052 D 227377 CDS NP_819937.1 29654245 1208817 complement(874177..874845) 1 NC_002971.3 O-methyltransferase 874845 1208817 CBU_0924 Coxiella burnetii RSA 493 O-methyltransferase NP_819937.1 874177 R 227377 CDS NP_819938.1 29654246 1208818 complement(874847..875848) 1 NC_002971.3 lytic murein transglycosylase 875848 1208818 CBU_0925 Coxiella burnetii RSA 493 lytic murein transglycosylase NP_819938.1 874847 R 227377 CDS NP_819939.1 29654247 1208819 complement(875949..876842) 1 NC_002971.3 3-hydroxyisobutyrate dehydrogenase 876842 mmsB 1208819 mmsB Coxiella burnetii RSA 493 3-hydroxyisobutyrate dehydrogenase NP_819939.1 875949 R 227377 CDS NP_819940.1 29654248 1208820 complement(876852..878348) 1 NC_002971.3 methylmalonate-semialdehyde dehydrogenase (acylating); malonate-semialdehyde dehydrogenase (acetylating) 878348 mmsA 1208820 mmsA Coxiella burnetii RSA 493 malonate-semialdehyde dehydrogenase (acetylating) NP_819940.1 876852 R 227377 CDS NP_819941.1 29654249 1208821 complement(878380..878970) 1 NC_002971.3 pyridoxamine 5'-phosphate oxidase 878970 pdxH 1208821 pdxH Coxiella burnetii RSA 493 pyridoxamine 5'-phosphate oxidase NP_819941.1 878380 R 227377 CDS NP_819942.1 29654250 1208822 complement(878992..879837) 1 NC_002971.3 short chain dehydrogenase/reductase oxidoreductase 879837 1208822 CBU_0929 Coxiella burnetii RSA 493 short chain dehydrogenase/reductase oxidoreductase NP_819942.1 878992 R 227377 CDS NP_819943.1 29654251 1208823 complement(879827..880507) 1 NC_002971.3 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 880507 1208823 CBU_0930 Coxiella burnetii RSA 493 3-methyladenine DNA glycosylase NP_819943.1 879827 R 227377 CDS NP_819944.2 215919067 1208824 complement(880491..881993) 1 NC_002971.3 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 881993 glpD 1208824 glpD Coxiella burnetii RSA 493 glycerol-3-phosphate dehydrogenase NP_819944.2 880491 R 227377 CDS NP_819945.2 215919068 1208825 882060..883604 1 NC_002971.3 glycerol kinase 883604 gplK 1208825 gplK Coxiella burnetii RSA 493 glycerol kinase NP_819945.2 882060 D 227377 CDS NP_819946.1 29654254 1208826 complement(883573..884346) 1 NC_002971.3 ABC transporter permease 884346 1208826 CBU_0933 Coxiella burnetii RSA 493 ABC transporter permease NP_819946.1 883573 R 227377 CDS NP_819947.1 29654255 1208827 complement(884347..885261) 1 NC_002971.3 ABC transporter ATP-binding protein 885261 1208827 CBU_0934 Coxiella burnetii RSA 493 ABC transporter ATP-binding protein NP_819947.1 884347 R 227377 CDS NP_819948.1 29654256 1208828 complement(885267..885656) 1 NC_002971.3 RNA binding protein 885656 1208828 CBU_0935 Coxiella burnetii RSA 493 RNA binding protein NP_819948.1 885267 R 227377 CDS NP_819949.1 29654257 1208829 complement(885849..886418) 1 NC_002971.3 OmpA-like transmembrane domain-containing protein 886418 1208829 CBU_0936 Coxiella burnetii RSA 493 OmpA-like transmembrane domain-containing protein NP_819949.1 885849 R 227377 CDS NP_819950.2 215919069 1208830 886730..888181 1 NC_002971.3 hypothetical protein 888181 1208830 CBU_0937 Coxiella burnetii RSA 493 hypothetical protein NP_819950.2 886730 D 227377 CDS NP_819951.2 215919070 1208833 889062..890588 1 NC_002971.3 AsmA family protein 890588 1208833 CBU_0939 Coxiella burnetii RSA 493 AsmA family protein NP_819951.2 889062 D 227377 CDS NP_819952.1 29654260 1208834 890594..891658 1 NC_002971.3 A/G-specific adenine glycosylase 891658 mutY 1208834 mutY Coxiella burnetii RSA 493 A/G-specific adenine glycosylase NP_819952.1 890594 D 227377 CDS NP_819953.1 29654261 1208835 891655..891927 1 NC_002971.3 hypothetical protein 891927 1208835 CBU_0941 Coxiella burnetii RSA 493 hypothetical protein NP_819953.1 891655 D 227377 CDS NP_819954.1 29654262 1208836 complement(891929..892312) 1 NC_002971.3 hypothetical protein 892312 1208836 CBU_0942 Coxiella burnetii RSA 493 hypothetical protein NP_819954.1 891929 R 227377 CDS NP_819955.2 215919071 1208837 892388..892828 1 NC_002971.3 rhodanese-like domain-containing protein 892828 1208837 CBU_0943 Coxiella burnetii RSA 493 rhodanese-like domain-containing protein NP_819955.2 892388 D 227377 CDS NP_819956.1 29654264 1208839 complement(893316..893417) 1 NC_002971.3 hypothetical protein 893417 1208839 CBU_0944 Coxiella burnetii RSA 493 hypothetical protein NP_819956.1 893316 R 227377 CDS NP_819957.1 29654265 1208840 complement(893658..894629) 1 NC_002971.3 hypothetical protein 894629 1208840 CBU_0945 Coxiella burnetii RSA 493 hypothetical protein NP_819957.1 893658 R 227377 CDS NP_819958.1 29654266 1208841 complement(894754..895740) 1 NC_002971.3 death-on-curing family protein 895740 rhuM 1208841 rhuM Coxiella burnetii RSA 493 death-on-curing family protein NP_819958.1 894754 R 227377 CDS NP_819959.1 29654267 1208843 897282..897737 1 NC_002971.3 hypothetical protein 897737 1208843 CBU_0948 Coxiella burnetii RSA 493 hypothetical protein NP_819959.1 897282 D 227377 CDS NP_819960.1 29654268 1208844 complement(897877..898245) 1 NC_002971.3 hypothetical protein 898245 1208844 CBU_0949 Coxiella burnetii RSA 493 hypothetical protein NP_819960.1 897877 R 227377 CDS NP_819961.1 29654269 1208847 complement(902551..903234) 1 NC_002971.3 hypothetical protein 903234 1208847 CBU_0952 Coxiella burnetii RSA 493 hypothetical protein NP_819961.1 902551 R 227377 CDS NP_819962.2 215919072 1208848 complement(903323..904648) 1 NC_002971.3 amino acid permease 904648 1208848 CBU_0953 Coxiella burnetii RSA 493 amino acid permease NP_819962.2 903323 R 227377 CDS NP_819963.1 29654271 1208849 complement(904685..905431) 1 NC_002971.3 phosphohydrolase 905431 1208849 CBU_0954 Coxiella burnetii RSA 493 phosphohydrolase NP_819963.1 904685 R 227377 CDS NP_819964.1 29654272 1208850 complement(905450..906103) 1 NC_002971.3 LuxR family transcriptional regulator 906103 gacA.3 1208850 gacA.3 Coxiella burnetii RSA 493 LuxR family transcriptional regulator NP_819964.1 905450 R 227377 CDS NP_819965.1 29654273 1208851 complement(906240..906902) 1 NC_002971.3 hypothetical protein 906902 1208851 CBU_0956 Coxiella burnetii RSA 493 hypothetical protein NP_819965.1 906240 R 227377 CDS NP_819966.1 29654274 1208852 907098..908342 1 NC_002971.3 hypothetical protein 908342 1208852 CBU_0957 Coxiella burnetii RSA 493 hypothetical protein NP_819966.1 907098 D 227377 CDS NP_819967.1 29654275 1208854 complement(912300..913529) 1 NC_002971.3 Bcr/CflA subfamily drug resistance transporter 913529 1208854 CBU_0959 Coxiella burnetii RSA 493 Bcr/CflA subfamily drug resistance transporter NP_819967.1 912300 R 227377 CDS NP_819968.1 29654276 1208855 913674..914225 1 NC_002971.3 DNA-binding protein/cupin domain protein 914225 1208855 CBU_0960 Coxiella burnetii RSA 493 DNA-binding protein/cupin domain protein NP_819968.1 913674 D 227377 CDS NP_819969.2 215919073 1208856 914235..914408 1 NC_002971.3 hypothetical protein 914408 1208856 CBU_0961 Coxiella burnetii RSA 493 hypothetical protein NP_819969.2 914235 D 227377 CDS NP_819970.1 29654278 1208857 complement(914419..915117) 1 NC_002971.3 short chain dehydrogenase/reductase oxidoreductase 915117 1208857 CBU_0962 Coxiella burnetii RSA 493 short chain dehydrogenase/reductase oxidoreductase NP_819970.1 914419 R 227377 CDS NP_819971.2 215919074 1208858 complement(915117..915641) 1 NC_002971.3 antioxidant, AhpC/TSA family 915641 bcp 1208858 bcp Coxiella burnetii RSA 493 antioxidant, AhpC/TSA family NP_819971.2 915117 R 227377 CDS NP_819972.2 215919075 1208859 915645..916556 1 NC_002971.3 hypothetical protein 916556 1208859 CBU_0964 Coxiella burnetii RSA 493 hypothetical protein NP_819972.2 915645 D 227377 CDS YP_002332977.1 215919076 7065946 916841..917029 1 NC_002971.3 hypothetical protein 917029 7065946 CBU_0964a Coxiella burnetii RSA 493 hypothetical protein YP_002332977.1 916841 D 227377 CDS NP_819973.1 29654281 1208860 917026..918591 1 NC_002971.3 cytochrome d ubiquinol oxidase subunit I 918591 cydA-2 1208860 cydA-2 Coxiella burnetii RSA 493 cytochrome d ubiquinol oxidase subunit I NP_819973.1 917026 D 227377 CDS NP_819974.1 29654282 1208861 918588..919721 1 NC_002971.3 cytochrome d ubiquinol oxidase subunit II 919721 cydB 1208861 cydB Coxiella burnetii RSA 493 cytochrome d ubiquinol oxidase subunit II NP_819974.1 918588 D 227377 CDS NP_819975.2 215919077 1208862 919732..919836 1 NC_002971.3 cyd operon protein YbgT 919836 ybgT 1208862 ybgT Coxiella burnetii RSA 493 cyd operon protein YbgT NP_819975.2 919732 D 227377 CDS NP_819976.1 29654284 1208863 complement(919965..920495) 1 NC_002971.3 phospholipase D 920495 1208863 CBU_0968 Coxiella burnetii RSA 493 phospholipase D NP_819976.1 919965 R 227377 CDS NP_819978.1 29654286 1208865 920613..921668 1 NC_002971.3 hypothetical protein 921668 1208865 CBU_0970 Coxiella burnetii RSA 493 hypothetical protein NP_819978.1 920613 D 227377 CDS NP_819979.1 29654287 1208866 complement(921665..922708) 1 NC_002971.3 'catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors'; dihydroorotate dehydrogenase 2 922708 pyrD 1208866 pyrD Coxiella burnetii RSA 493 dihydroorotate dehydrogenase 2 NP_819979.1 921665 R 227377 CDS NP_819980.1 29654288 1208867 complement(922705..923397) 1 NC_002971.3 hypothetical protein 923397 1208867 CBU_0972 Coxiella burnetii RSA 493 hypothetical protein NP_819980.1 922705 R 227377 CDS NP_819981.1 29654289 1208868 923486..924649 1 NC_002971.3 isovaleryl-CoA dehydrogenase 924649 1208868 CBU_0973 Coxiella burnetii RSA 493 isovaleryl-CoA dehydrogenase NP_819981.1 923486 D 227377 CDS NP_819982.1 29654290 1208869 924649..925833 1 NC_002971.3 acetyl-CoA acetyltransferase 925833 1208869 CBU_0974 Coxiella burnetii RSA 493 acetyl-CoA acetyltransferase NP_819982.1 924649 D 227377 CDS NP_819983.2 215919078 1208870 925858..927522 1 NC_002971.3 acyl-CoA biotin-dependent carboxyltransferase 927522 1208870 CBU_0975 Coxiella burnetii RSA 493 acyl-CoA biotin-dependent carboxyltransferase NP_819983.2 925858 D 227377 CDS NP_819984.1 29654292 1208871 927542..928312 1 NC_002971.3 methylglutaconyl-CoA hydratase 928312 1208871 CBU_0976 Coxiella burnetii RSA 493 methylglutaconyl-CoA hydratase NP_819984.1 927542 D 227377 CDS NP_819985.1 29654293 1208872 928314..930299 1 NC_002971.3 biotin carboxylase 930299 1208872 CBU_0977 Coxiella burnetii RSA 493 biotin carboxylase NP_819985.1 928314 D 227377 CDS NP_819986.1 29654294 1208873 930350..930817 1 NC_002971.3 hypothetical protein 930817 1208873 CBU_0978 Coxiella burnetii RSA 493 hypothetical protein NP_819986.1 930350 D 227377 CDS NP_819987.1 29654295 1208874 complement(930848..931150) 1 NC_002971.3 lipoprotein 931150 1208874 CBU_0979 Coxiella burnetii RSA 493 lipoprotein NP_819987.1 930848 R 227377 CDS NP_819988.1 29654296 1208875 complement(931240..931518) 1 NC_002971.3 lipoprotein 931518 1208875 CBU_0980 Coxiella burnetii RSA 493 lipoprotein NP_819988.1 931240 R 227377 CDS NP_819989.1 29654297 1208876 931661..931753 1 NC_002971.3 hypothetical protein 931753 1208876 CBU_0981 Coxiella burnetii RSA 493 hypothetical protein NP_819989.1 931661 D 227377 CDS NP_819990.1 29654298 1208877 931822..932904 1 NC_002971.3 'catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive'; phospho-2-dehydro-3-deoxyheptonate aldolase 932904 1208877 CBU_0982 Coxiella burnetii RSA 493 phospho-2-dehydro-3-deoxyheptonate aldolase NP_819990.1 931822 D 227377 CDS NP_819991.1 29654299 1208879 933752..934528 1 NC_002971.3 prephenate dehydrogenase 934528 1208879 CBU_0984 Coxiella burnetii RSA 493 prephenate dehydrogenase NP_819991.1 933752 D 227377 CDS NP_819992.1 29654300 1208880 934557..935315 1 NC_002971.3 hypothetical protein 935315 1208880 CBU_0985 Coxiella burnetii RSA 493 hypothetical protein NP_819992.1 934557 D 227377 CDS NP_819993.2 215919079 1208881 complement(935372..936184) 1 NC_002971.3 RNA methyltransferase 936184 1208881 CBU_0986 Coxiella burnetii RSA 493 RNA methyltransferase NP_819993.2 935372 R 227377 CDS NP_819994.2 215919080 1208882 936218..937015 1 NC_002971.3 rare lipoprotein A 937015 1208882 CBU_0987 Coxiella burnetii RSA 493 rare lipoprotein A NP_819994.2 936218 D 227377 CDS NP_819995.1 29654303 1208883 937019..937708 1 NC_002971.3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 937708 ung 1208883 ung Coxiella burnetii RSA 493 uracil-DNA glycosylase NP_819995.1 937019 D 227377 CDS NP_820000.1 29654308 1208889 941108..941620 1 NC_002971.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 941620 def 1208889 def Coxiella burnetii RSA 493 peptide deformylase NP_820000.1 941108 D 227377 CDS NP_820001.1 29654309 1208890 complement(941691..941798) 1 NC_002971.3 hypothetical protein 941798 1208890 CBU_0994 Coxiella burnetii RSA 493 hypothetical protein NP_820001.1 941691 R 227377 CDS NP_820002.2 215919081 1208891 941938..942222 1 NC_002971.3 cytochrome c oxidase, membrane subunit 942222 1208891 CBU_0995 Coxiella burnetii RSA 493 cytochrome c oxidase, membrane subunit NP_820002.2 941938 D 227377 CDS NP_820003.1 29654311 1208892 942219..943136 1 NC_002971.3 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 943136 ctaB 1208892 ctaB Coxiella burnetii RSA 493 protoheme IX farnesyltransferase NP_820003.1 942219 D 227377 CDS NP_820004.2 215919082 1208893 943145..943261 1 NC_002971.3 lipoprotein 943261 1208893 CBU_0997 Coxiella burnetii RSA 493 lipoprotein NP_820004.2 943145 D 227377 CDS NP_820005.1 29654313 1208894 complement(943294..944601) 1 NC_002971.3 'catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis'; adenylosuccinate synthetase 944601 purA 1208894 purA Coxiella burnetii RSA 493 adenylosuccinate synthetase NP_820005.1 943294 R 227377 CDS NP_820006.2 215919083 1208895 complement(944622..945986) 1 NC_002971.3 GTP-binding protein HflX 945986 hflX 1208895 hflX Coxiella burnetii RSA 493 GTP-binding protein HflX NP_820006.2 944622 R 227377 CDS NP_820007.1 29654315 1208896 complement(945983..946684) 1 NC_002971.3 lipoprotein releasing system, ATP-binding protein 946684 lolD 1208896 lolD Coxiella burnetii RSA 493 lipoprotein releasing system, ATP-binding protein NP_820007.1 945983 R 227377 CDS NP_820008.1 29654316 1208897 complement(946677..947921) 1 NC_002971.3 lipoprotein releasing system transmembrane protein LolC/E family 947921 lolC 1208897 lolC Coxiella burnetii RSA 493 lipoprotein releasing system transmembrane protein LolC/E family NP_820008.1 946677 R 227377 CDS NP_820009.1 29654317 1208898 948044..949015 1 NC_002971.3 bifunctional biotin operon repressor/biotin synthetase BirA 949015 birA 1208898 birA Coxiella burnetii RSA 493 bifunctional biotin operon repressor/biotin synthetase BirA NP_820009.1 948044 D 227377 CDS NP_820010.1 29654318 1208899 complement(948943..949671) 1 NC_002971.3 dethiobiotin synthetase 949671 bioD 1208899 bioD Coxiella burnetii RSA 493 dethiobiotin synthetase NP_820010.1 948943 R 227377 CDS NP_820011.1 29654319 1208900 complement(949668..950414) 1 NC_002971.3 biotin biosynthesis protein BioC 950414 bioC.2 1208900 bioC.2 Coxiella burnetii RSA 493 biotin biosynthesis protein BioC NP_820011.1 949668 R 227377 CDS NP_820012.1 29654320 1208901 complement(950404..951108) 1 NC_002971.3 carboxylesterase BioH 951108 bioH 1208901 bioH Coxiella burnetii RSA 493 carboxylesterase BioH NP_820012.1 950404 R 227377 CDS NP_820013.1 29654321 1208902 complement(951102..952256) 1 NC_002971.3 8-amino-7-oxononanoate synthase 952256 bioF 1208902 bioF Coxiella burnetii RSA 493 8-amino-7-oxononanoate synthase NP_820013.1 951102 R 227377 CDS NP_820014.1 29654322 1208903 complement(952243..953208) 1 NC_002971.3 biotin synthase 953208 bioB 1208903 bioB Coxiella burnetii RSA 493 biotin synthase NP_820014.1 952243 R 227377 CDS NP_820015.1 29654323 1208904 953577..954905 1 NC_002971.3 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 954905 bioA 1208904 bioA Coxiella burnetii RSA 493 adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_820015.1 953577 D 227377 CDS NP_820016.2 215919084 1208906 955210..955590 1 NC_002971.3 hypothetical protein 955590 1208906 CBU_1010 Coxiella burnetii RSA 493 hypothetical protein NP_820016.2 955210 D 227377 CDS NP_820017.1 29654325 1208907 complement(955641..956825) 1 NC_002971.3 lignostilbene-alpha,beta-dioxygenase 956825 1208907 CBU_1011 Coxiella burnetii RSA 493 lignostilbene-alpha,beta-dioxygenase NP_820017.1 955641 R 227377 CDS NP_820020.1 29654328 1208912 960466..960660 1 NC_002971.3 hypothetical protein 960660 1208912 CBU_1014 Coxiella burnetii RSA 493 hypothetical protein NP_820020.1 960466 D 227377 CDS NP_820021.1 29654329 1208913 961125..961670 1 NC_002971.3 hypothetical protein 961670 1208913 CBU_1015 Coxiella burnetii RSA 493 hypothetical protein NP_820021.1 961125 D 227377 CDS NP_820022.1 29654330 1208914 961969..962121 1 NC_002971.3 hypothetical protein 962121 1208914 CBU_1016 Coxiella burnetii RSA 493 hypothetical protein NP_820022.1 961969 D 227377 CDS NP_820023.1 29654331 1208915 962236..963378 1 NC_002971.3 ATPase 963378 1208915 CBU_1017 Coxiella burnetii RSA 493 ATPase NP_820023.1 962236 D 227377 CDS NP_820024.1 29654332 1208916 complement(963556..963912) 1 NC_002971.3 hypothetical protein 963912 1208916 CBU_1018 Coxiella burnetii RSA 493 hypothetical protein NP_820024.1 963556 R 227377 CDS NP_820025.2 215919085 1208917 complement(963953..964171) 1 NC_002971.3 hypothetical protein 964171 1208917 CBU_1019 Coxiella burnetii RSA 493 hypothetical protein NP_820025.2 963953 R 227377 CDS NP_820026.1 29654334 1208918 complement(964423..964674) 1 NC_002971.3 hypothetical protein 964674 1208918 CBU_1020 Coxiella burnetii RSA 493 hypothetical protein NP_820026.1 964423 R 227377 CDS NP_820027.1 29654335 1208919 964833..965276 1 NC_002971.3 nucleotidyltransferase 965276 1208919 CBU_1021 Coxiella burnetii RSA 493 nucleotidyltransferase NP_820027.1 964833 D 227377 CDS NP_820028.1 29654336 1208920 965269..965568 1 NC_002971.3 nucleotidyltransferase domain-containing protein 965568 1208920 CBU_1022 Coxiella burnetii RSA 493 nucleotidyltransferase domain-containing protein NP_820028.1 965269 D 227377 CDS NP_820029.2 215919086 1208921 966353..967309 1 NC_002971.3 quinone oxidoreductase 967309 1208921 CBU_1023 Coxiella burnetii RSA 493 quinone oxidoreductase NP_820029.2 966353 D 227377 CDS YP_002332978.1 215919087 7065933 967315..967593 1 NC_002971.3 hypothetical protein 967593 7065933 CBU_1023a Coxiella burnetii RSA 493 hypothetical protein YP_002332978.1 967315 D 227377 CDS NP_820033.1 29654341 1208925 970617..972008 1 NC_002971.3 ATPase 972008 1208925 CBU_1027 Coxiella burnetii RSA 493 ATPase NP_820033.1 970617 D 227377 CDS NP_820034.1 29654342 1208926 complement(972024..972926) 1 NC_002971.3 hypothetical protein 972926 1208926 CBU_1028 Coxiella burnetii RSA 493 hypothetical protein NP_820034.1 972024 R 227377 CDS NP_820035.2 215919088 1208929 974769..975209 1 NC_002971.3 phage lysozyme 975209 1208929 CBU_1031 Coxiella burnetii RSA 493 phage lysozyme NP_820035.2 974769 D 227377 CDS NP_820038.2 215919089 1208933 complement(976258..976893) 1 NC_002971.3 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 976893 pgsA 1208933 pgsA Coxiella burnetii RSA 493 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP_820038.2 976258 R 227377 CDS NP_820039.1 29654347 1208934 976940..978346 1 NC_002971.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 978346 1208934 CBU_1035 Coxiella burnetii RSA 493 nicotinate phosphoribosyltransferase NP_820039.1 976940 D 227377 CDS YP_002332979.1 215919090 7065873 complement(980466..980801) 1 NC_002971.3 cytochrome O ubiquinol oxidase 980801 cyoD 7065873 cyoD Coxiella burnetii RSA 493 cytochrome O ubiquinol oxidase YP_002332979.1 980466 R 227377 CDS NP_820040.1 29654348 1208938 complement(980798..981394) 1 NC_002971.3 cytochrome c oxidase polypeptide III 981394 cyoC 1208938 cyoC Coxiella burnetii RSA 493 cytochrome c oxidase polypeptide III NP_820040.1 980798 R 227377 CDS NP_820041.1 29654349 1208939 complement(981391..983397) 1 NC_002971.3 cytochrome c oxidase polypeptide I 983397 cyoB 1208939 cyoB Coxiella burnetii RSA 493 cytochrome c oxidase polypeptide I NP_820041.1 981391 R 227377 CDS NP_820042.1 29654350 1208940 complement(983417..984313) 1 NC_002971.3 cytochrome c oxidase polypeptide II 984313 cyoA 1208940 cyoA Coxiella burnetii RSA 493 cytochrome c oxidase polypeptide II NP_820042.1 983417 R 227377 CDS NP_820043.1 29654351 1208941 complement(984321..984476) 1 NC_002971.3 hypothetical protein 984476 1208941 CBU_1041 Coxiella burnetii RSA 493 hypothetical protein NP_820043.1 984321 R 227377 CDS NP_820044.1 29654352 1208942 984470..984871 1 NC_002971.3 hypothetical protein 984871 1208942 CBU_1042 Coxiella burnetii RSA 493 hypothetical protein NP_820044.1 984470 D 227377 CDS NP_820045.1 29654353 1208943 complement(984914..985558) 1 NC_002971.3 LuxR family transcriptional regulator 985558 gacA.4 1208943 gacA.4 Coxiella burnetii RSA 493 LuxR family transcriptional regulator NP_820045.1 984914 R 227377 CDS YP_002332980.1 215919091 7065951 complement(988083..988196) 1 NC_002971.3 hypothetical protein 988196 7065951 CBU_1045a Coxiella burnetii RSA 493 hypothetical protein YP_002332980.1 988083 R 227377 CDS NP_820051.1 29654359 1208951 complement(993188..993400) 1 NC_002971.3 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 993400 csrA-2 1208951 csrA-2 Coxiella burnetii RSA 493 carbon storage regulator NP_820051.1 993188 R 227377 CDS NP_820052.1 29654360 1208952 complement(993540..994769) 1 NC_002971.3 aspartokinase 994769 1208952 CBU_1051 Coxiella burnetii RSA 493 aspartokinase NP_820052.1 993540 R 227377 CDS NP_820053.1 29654361 1208953 complement(994775..997372) 1 NC_002971.3 'Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'; alanyl-tRNA synthetase 997372 alaS 1208953 alaS Coxiella burnetii RSA 493 alanyl-tRNA synthetase NP_820053.1 994775 R 227377 CDS NP_820054.1 29654362 1208954 complement(997365..997799) 1 NC_002971.3 regulatory protein RecX 997799 recX 1208954 recX Coxiella burnetii RSA 493 regulatory protein RecX NP_820054.1 997365 R 227377 CDS NP_820055.1 29654363 1208955 complement(997796..998827) 1 NC_002971.3 'catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs'; recombinase A 998827 recA 1208955 recA Coxiella burnetii RSA 493 recombinase A NP_820055.1 997796 R 227377 CDS NP_820056.1 29654364 1208956 complement(998915..999415) 1 NC_002971.3 competence/damage inducible protein CinA 999415 1208956 CBU_1055 Coxiella burnetii RSA 493 competence/damage inducible protein CinA NP_820056.1 998915 R 227377 CDS NP_820057.2 215919092 1208957 999550..1002165 1 NC_002971.3 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1002165 mutS 1208957 mutS Coxiella burnetii RSA 493 DNA mismatch repair protein MutS NP_820057.2 999550 D 227377 CDS NP_820058.1 29654366 1208958 1002162..1002905 1 NC_002971.3 cell wall biosynthesis glycosyltransferase 1002905 1208958 CBU_1057 Coxiella burnetii RSA 493 cell wall biosynthesis glycosyltransferase NP_820058.1 1002162 D 227377 CDS NP_820059.1 29654367 1208959 1002918..1004204 1 NC_002971.3 hypothetical protein 1004204 1208959 CBU_1058 Coxiella burnetii RSA 493 hypothetical protein NP_820059.1 1002918 D 227377 CDS YP_338282.1 77358718 1208960 complement(1004175..1004909) 1 NC_002971.3 RNA pseudouridine synthase 1004909 1208960 CBU_1059 Coxiella burnetii RSA 493 RNA pseudouridine synthase YP_338282.1 1004175 R 227377 CDS NP_820060.1 29654368 1208961 complement(1004919..1005548) 1 NC_002971.3 segregation and condensation protein 1005548 scpB 1208961 scpB Coxiella burnetii RSA 493 segregation and condensation protein NP_820060.1 1004919 R 227377 CDS NP_820061.2 215919093 1208962 complement(1005553..1006380) 1 NC_002971.3 segregation and condensation protein 1006380 scpA 1208962 scpA Coxiella burnetii RSA 493 segregation and condensation protein NP_820061.2 1005553 R 227377 CDS YP_002332981.1 215919094 7065922 1006431..1007537 1 NC_002971.3 hypothetical protein 1007537 7065922 CBU_1061a Coxiella burnetii RSA 493 hypothetical protein YP_002332981.1 1006431 D 227377 CDS NP_820063.1 29654371 1208964 1007671..1009077 1 NC_002971.3 hypothetical protein 1009077 1208964 CBU_1063 Coxiella burnetii RSA 493 hypothetical protein NP_820063.1 1007671 D 227377 CDS NP_820064.1 29654372 1208965 complement(1009083..1009367) 1 NC_002971.3 hypothetical protein 1009367 1208965 CBU_1064 Coxiella burnetii RSA 493 hypothetical protein NP_820064.1 1009083 R 227377 CDS NP_820065.1 29654373 1208966 complement(1009395..1009949) 1 NC_002971.3 2'-5' RNA ligase 1009949 1208966 CBU_1065 Coxiella burnetii RSA 493 2'-5' RNA ligase NP_820065.1 1009395 R 227377 CDS NP_820066.1 29654374 1208967 1010006..1011787 1 NC_002971.3 transporter, divalent anion:sodium symporter family 1011787 1208967 CBU_1066 Coxiella burnetii RSA 493 transporter, divalent anion:sodium symporter family NP_820066.1 1010006 D 227377 CDS NP_820067.1 29654375 1208968 complement(1011784..1012554) 1 NC_002971.3 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1012554 ttcA 1208968 ttcA Coxiella burnetii RSA 493 C32 tRNA thiolase NP_820067.1 1011784 R 227377 CDS YP_002332982.1 215919095 7065943 1012620..1014368 1 NC_002971.3 adenylate cyclase 1014368 7065943 CBU_1067a Coxiella burnetii RSA 493 adenylate cyclase YP_002332982.1 1012620 D 227377 CDS NP_820070.2 215919096 1208972 complement(1016678..1017106) 1 NC_002971.3 DoxX family protein 1017106 1208972 CBU_1071 Coxiella burnetii RSA 493 DoxX family protein NP_820070.2 1016678 R 227377 CDS NP_820071.1 29654379 1208973 1017271..1018428 1 NC_002971.3 queuine tRNA-ribosyltransferase 1018428 tgt 1208973 tgt Coxiella burnetii RSA 493 queuine tRNA-ribosyltransferase NP_820071.1 1017271 D 227377 CDS NP_820072.1 29654380 1208974 1018432..1018938 1 NC_002971.3 hypothetical protein 1018938 1208974 CBU_1073 Coxiella burnetii RSA 493 hypothetical protein NP_820072.1 1018432 D 227377 CDS NP_820073.1 29654381 1208975 complement(1018960..1019520) 1 NC_002971.3 'Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively'; hypoxanthine-guanine phosphoribosyltransferase 1019520 1208975 CBU_1074 Coxiella burnetii RSA 493 hypoxanthine-guanine phosphoribosyltransferase NP_820073.1 1018960 R 227377 CDS NP_820074.1 29654382 1208976 complement(1019507..1020658) 1 NC_002971.3 transporter, small conductance mechanosensitive ion channel (MscS) family 1020658 1208976 CBU_1075 Coxiella burnetii RSA 493 transporter, small conductance mechanosensitive ion channel (MscS) family NP_820074.1 1019507 R 227377 CDS YP_002332983.1 215919097 7065881 1020878..1021150 1 NC_002971.3 hypothetical protein 1021150 7065881 CBU_1075a Coxiella burnetii RSA 493 hypothetical protein YP_002332983.1 1020878 D 227377 CDS NP_820075.2 215919098 1208977 complement(1021147..1022241) 1 NC_002971.3 IS1111A transposase 1022241 1208977 CBU_1076 Coxiella burnetii RSA 493 IS1111A transposase NP_820075.2 1021147 R 227377 CDS NP_820076.1 29654384 1208978 complement(1022308..1023249) 1 NC_002971.3 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1023249 nagZ 1208978 nagZ Coxiella burnetii RSA 493 beta-hexosaminidase NP_820076.1 1022308 R 227377 CDS NP_820077.1 29654385 1208979 complement(1023253..1023591) 1 NC_002971.3 hypothetical protein 1023591 1208979 CBU_1078 Coxiella burnetii RSA 493 hypothetical protein NP_820077.1 1023253 R 227377 CDS NP_820078.1 29654386 1208980 complement(1023599..1024195) 1 NC_002971.3 hypothetical protein 1024195 1208980 CBU_1079 Coxiella burnetii RSA 493 hypothetical protein NP_820078.1 1023599 R 227377 CDS NP_820079.1 29654387 1208981 complement(1024273..1024755) 1 NC_002971.3 ErfK/YbiS/YcfS/YnhG family protein 1024755 1208981 CBU_1080 Coxiella burnetii RSA 493 ErfK/YbiS/YcfS/YnhG family protein NP_820079.1 1024273 R 227377 CDS NP_820080.2 215919099 1208982 complement(1024828..1025166) 1 NC_002971.3 hypothetical protein 1025166 1208982 CBU_1081 Coxiella burnetii RSA 493 hypothetical protein NP_820080.2 1024828 R 227377 CDS NP_820081.1 29654389 1208983 complement(1025348..1026283) 1 NC_002971.3 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1026283 miaA 1208983 miaA Coxiella burnetii RSA 493 tRNA delta(2)-isopentenylpyrophosphate transferase NP_820081.1 1025348 R 227377 CDS NP_820082.2 215919100 1208984 complement(1026287..1028014) 1 NC_002971.3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1028014 mutL 1208984 mutL Coxiella burnetii RSA 493 DNA mismatch repair protein NP_820082.2 1026287 R 227377 CDS NP_820083.1 29654391 1208985 complement(1028075..1030126) 1 NC_002971.3 hypothetical protein 1030126 1208985 CBU_1084 Coxiella burnetii RSA 493 hypothetical protein NP_820083.1 1028075 R 227377 CDS NP_820084.2 215919101 1208986 complement(1030164..1031381) 1 NC_002971.3 N-acetylmuramoyl-L-alanine amidase 1031381 1208986 CBU_1085 Coxiella burnetii RSA 493 N-acetylmuramoyl-L-alanine amidase NP_820084.2 1030164 R 227377 CDS NP_820085.1 29654393 1208987 1031508..1032500 1 NC_002971.3 IS30 family transposase 1032500 1208987 CBU_1086 Coxiella burnetii RSA 493 IS30 family transposase NP_820085.1 1031508 D 227377 CDS NP_820086.1 29654394 1208988 complement(1032543..1032989) 1 NC_002971.3 hypothetical protein 1032989 1208988 CBU_1087 Coxiella burnetii RSA 493 hypothetical protein NP_820086.1 1032543 R 227377 CDS NP_820087.1 29654395 1208989 complement(1033003..1034469) 1 NC_002971.3 carbohydrate kinase 1034469 1208989 CBU_1088 Coxiella burnetii RSA 493 carbohydrate kinase NP_820087.1 1033003 R 227377 CDS NP_820088.1 29654396 1208990 1034505..1034603 1 NC_002971.3 hypothetical protein 1034603 1208990 CBU_1089 Coxiella burnetii RSA 493 hypothetical protein NP_820088.1 1034505 D 227377 CDS NP_820089.2 215919102 1208991 1034651..1035745 1 NC_002971.3 IS1111A transposase 1035745 1208991 CBU_1090 Coxiella burnetii RSA 493 IS1111A transposase NP_820089.2 1034651 D 227377 CDS YP_002332984.1 215919103 7065940 complement(1035742..1036014) 1 NC_002971.3 hypothetical protein 1036014 7065940 CBU_1090a Coxiella burnetii RSA 493 hypothetical protein YP_002332984.1 1035742 R 227377 CDS NP_820090.2 215919104 1208992 complement(1036184..1038433) 1 NC_002971.3 ribonuclease R 1038433 vacB 1208992 vacB Coxiella burnetii RSA 493 ribonuclease R NP_820090.2 1036184 R 227377 CDS NP_820091.1 29654399 1208993 1038475..1038705 1 NC_002971.3 lipoprotein 1038705 1208993 CBU_1092 Coxiella burnetii RSA 493 lipoprotein NP_820091.1 1038475 D 227377 CDS NP_820092.1 29654400 1208994 complement(1038729..1041788) 1 NC_002971.3 AcrB/AcrD/AcrF family transporter 1041788 1208994 CBU_1093 Coxiella burnetii RSA 493 AcrB/AcrD/AcrF family transporter NP_820092.1 1038729 R 227377 CDS NP_820093.1 29654401 1208995 complement(1041788..1042930) 1 NC_002971.3 RND family efflux transporter MFP subunit 1042930 1208995 CBU_1094 Coxiella burnetii RSA 493 RND family efflux transporter MFP subunit NP_820093.1 1041788 R 227377 CDS NP_820094.2 215919105 1208997 1043116..1043679 1 NC_002971.3 hypothetical protein 1043679 1208997 CBU_1095 Coxiella burnetii RSA 493 hypothetical protein NP_820094.2 1043116 D 227377 CDS NP_820095.2 215919106 1208998 1043683..1045062 1 NC_002971.3 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1045062 fumC 1208998 fumC Coxiella burnetii RSA 493 fumarate hydratase NP_820095.2 1043683 D 227377 CDS NP_820096.1 29654404 1208999 1045373..1046170 1 NC_002971.3 alpha-acetolactate decarboxylase 1046170 aldC 1208999 aldC Coxiella burnetii RSA 493 alpha-acetolactate decarboxylase NP_820096.1 1045373 D 227377 CDS NP_820097.1 29654405 1209000 complement(1046184..1047008) 1 NC_002971.3 hypothetical protein 1047008 1209000 CBU_1098 Coxiella burnetii RSA 493 hypothetical protein NP_820097.1 1046184 R 227377 CDS NP_820098.1 29654406 1209001 complement(1047144..1047923) 1 NC_002971.3 signal peptidase I 1047923 lepB-1 1209001 lepB-1 Coxiella burnetii RSA 493 signal peptidase I NP_820098.1 1047144 R 227377 CDS NP_820099.2 215919107 1209002 complement(1047933..1048361) 1 NC_002971.3 hypothetical protein 1048361 1209002 CBU_1100 Coxiella burnetii RSA 493 hypothetical protein NP_820099.2 1047933 R 227377 CDS YP_002332985.1 215919108 7065861 1048457..1048627 1 NC_002971.3 hypothetical protein 1048627 7065861 CBU_1100a Coxiella burnetii RSA 493 hypothetical protein YP_002332985.1 1048457 D 227377 CDS NP_820102.2 215919109 1209005 complement(1049776..1051056) 1 NC_002971.3 Slt family transglycosylase 1051056 1209005 CBU_1103 Coxiella burnetii RSA 493 Slt family transglycosylase NP_820102.2 1049776 R 227377 CDS NP_820103.1 29654411 1209006 1051234..1052226 1 NC_002971.3 IS30 family transposase 1052226 1209006 CBU_1104 Coxiella burnetii RSA 493 IS30 family transposase NP_820103.1 1051234 D 227377 CDS NP_820110.2 215919110 1209013 complement(1056925..1058139) 1 NC_002971.3 membrane-bound lytic murein transglycosylase A 1058139 1209013 CBU_1111 Coxiella burnetii RSA 493 membrane-bound lytic murein transglycosylase A NP_820110.2 1056925 R 227377 CDS NP_820111.2 215919111 1209014 complement(1058109..1058474) 1 NC_002971.3 GIY-YIG catalytic domain-containing protein 1058474 1209014 CBU_1112 Coxiella burnetii RSA 493 GIY-YIG catalytic domain-containing protein NP_820111.2 1058109 R 227377 CDS NP_820114.1 29654422 1209017 1059970..1060287 1 NC_002971.3 hypothetical protein 1060287 1209017 CBU_1115 Coxiella burnetii RSA 493 hypothetical protein NP_820114.1 1059970 D 227377 CDS NP_820115.1 29654423 1209018 complement(1060288..1061397) 1 NC_002971.3 alanine dehydrogenase 1061397 ald 1209018 ald Coxiella burnetii RSA 493 alanine dehydrogenase NP_820115.1 1060288 R 227377 CDS NP_820116.1 29654424 1209019 complement(1061426..1062370) 1 NC_002971.3 electron transfer flavoprotein subunit alpha 1062370 etfA 1209019 etfA Coxiella burnetii RSA 493 electron transfer flavoprotein subunit alpha NP_820116.1 1061426 R 227377 CDS NP_820117.1 29654425 1209020 complement(1062367..1063119) 1 NC_002971.3 electron transfer flavoprotein subunit beta 1063119 etfB 1209020 etfB Coxiella burnetii RSA 493 electron transfer flavoprotein subunit beta NP_820117.1 1062367 R 227377 CDS NP_820118.2 215919112 1209021 complement(1063116..1063937) 1 NC_002971.3 carboxymethylenebutenolidase 1063937 1209021 CBU_1119 Coxiella burnetii RSA 493 carboxymethylenebutenolidase NP_820118.2 1063116 R 227377 CDS NP_820119.1 29654427 1209022 1063960..1065585 1 NC_002971.3 electron-transferring-flavoprotein dehydrogenase 1065585 1209022 CBU_1120 Coxiella burnetii RSA 493 electron-transferring-flavoprotein dehydrogenase NP_820119.1 1063960 D 227377 CDS NP_820120.1 29654428 1209023 complement(1065580..1065762) 1 NC_002971.3 hypothetical protein 1065762 1209023 CBU_1121 Coxiella burnetii RSA 493 hypothetical protein NP_820120.1 1065580 R 227377 CDS NP_820121.2 215919113 1209024 1065790..1066551 1 NC_002971.3 enhanced entry protein 1066551 enhA.3 1209024 enhA.3 Coxiella burnetii RSA 493 enhanced entry protein NP_820121.2 1065790 D 227377 CDS NP_820122.2 215919114 1209025 1066703..1067728 1 NC_002971.3 curved DNA-binding protein 1067728 cbpA 1209025 cbpA Coxiella burnetii RSA 493 curved DNA-binding protein NP_820122.2 1066703 D 227377 CDS NP_820123.1 29654431 1209026 1067731..1068051 1 NC_002971.3 chaperone-modulator protein CbpM 1068051 1209026 CBU_1124 Coxiella burnetii RSA 493 chaperone-modulator protein CbpM NP_820123.1 1067731 D 227377 CDS NP_820126.2 215919115 1209029 complement(1069646..1070161) 1 NC_002971.3 hypothetical protein 1070161 1209029 CBU_1127 Coxiella burnetii RSA 493 hypothetical protein NP_820126.2 1069646 R 227377 CDS NP_820127.1 29654435 1209030 complement(1070161..1070520) 1 NC_002971.3 NifU-like N terminal domain protein 1070520 iscU.1 1209030 iscU.1 Coxiella burnetii RSA 493 NifU-like N terminal domain protein NP_820127.1 1070161 R 227377 CDS NP_820128.1 29654436 1209031 complement(1070527..1071717) 1 NC_002971.3 selenocysteine lyase; cysteine desulfurase 1071717 nifS 1209031 nifS Coxiella burnetii RSA 493 cysteine desulfurase NP_820128.1 1070527 R 227377 CDS NP_820129.2 215919116 1209032 complement(1071714..1073783) 1 NC_002971.3 OPT family oligopeptide transporter 1073783 1209032 CBU_1130 Coxiella burnetii RSA 493 OPT family oligopeptide transporter NP_820129.2 1071714 R 227377 CDS NP_820130.1 29654438 1209033 complement(1073774..1074496) 1 NC_002971.3 RNA methyltransferase 1074496 1209033 CBU_1131 Coxiella burnetii RSA 493 RNA methyltransferase NP_820130.1 1073774 R 227377 CDS NP_820131.1 29654439 1209034 1074591..1074689 1 NC_002971.3 hypothetical protein 1074689 1209034 CBU_1132 Coxiella burnetii RSA 493 hypothetical protein NP_820131.1 1074591 D 227377 CDS NP_820132.2 215919117 1209035 1074686..1075489 1 NC_002971.3 myo-inositol-1(or 4)-monophosphatase 1075489 suhB 1209035 suhB Coxiella burnetii RSA 493 myo-inositol-1(or 4)-monophosphatase NP_820132.2 1074686 D 227377 CDS NP_820133.1 29654441 1209036 complement(1075561..1076016) 1 NC_002971.3 hypothetical protein 1076016 1209036 CBU_1134 Coxiella burnetii RSA 493 hypothetical protein NP_820133.1 1075561 R 227377 CDS NP_820134.1 29654442 1209037 1076067..1076501 1 NC_002971.3 hypothetical protein 1076501 1209037 CBU_1135 Coxiella burnetii RSA 493 hypothetical protein NP_820134.1 1076067 D 227377 CDS NP_820135.1 29654443 1209038 complement(1076664..1079798) 1 NC_002971.3 enhanced entry protein enhC, tetratricopeptide repeat family 1079798 1209038 CBU_1136 Coxiella burnetii RSA 493 enhanced entry protein enhC, tetratricopeptide repeat family NP_820135.1 1076664 R 227377 CDS NP_820136.1 29654444 1209039 complement(1079795..1080349) 1 NC_002971.3 enhanced entry protein 1080349 enhB.2 1209039 enhB.2 Coxiella burnetii RSA 493 enhanced entry protein NP_820136.1 1079795 R 227377 CDS NP_820137.1 29654445 1209040 complement(1080352..1081098) 1 NC_002971.3 enhanced entry protein 1081098 enhA.4 1209040 enhA.4 Coxiella burnetii RSA 493 enhanced entry protein NP_820137.1 1080352 R 227377 CDS YP_002332986.1 215919118 7065908 complement(1081386..1081538) 1 NC_002971.3 hypothetical protein 1081538 7065908 CBU_1138a Coxiella burnetii RSA 493 hypothetical protein YP_002332986.1 1081386 R 227377 CDS NP_820138.2 215919119 1209041 complement(1081610..1081747) 1 NC_002971.3 hypothetical protein 1081747 1209041 CBU_1139 Coxiella burnetii RSA 493 hypothetical protein NP_820138.2 1081610 R 227377 CDS NP_820140.1 29654448 1209043 complement(1083113..1084027) 1 NC_002971.3 'forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF'; preprotein translocase subunit SecF 1084027 secF 1209043 secF Coxiella burnetii RSA 493 preprotein translocase subunit SecF NP_820140.1 1083113 R 227377 CDS NP_820141.1 29654449 1209044 complement(1084027..1085895) 1 NC_002971.3 protein translocase subunit 1085895 secD 1209044 secD Coxiella burnetii RSA 493 protein translocase subunit NP_820141.1 1084027 R 227377 CDS NP_820142.1 29654450 1209045 complement(1085911..1086261) 1 NC_002971.3 protein translocase subunit 1086261 yajC 1209045 yajC Coxiella burnetii RSA 493 protein translocase subunit NP_820142.1 1085911 R 227377 CDS NP_820143.1 29654451 1209046 complement(1086288..1086641) 1 NC_002971.3 hypothetical protein 1086641 1209046 CBU_1144 Coxiella burnetii RSA 493 hypothetical protein NP_820143.1 1086288 R 227377 CDS NP_820144.1 29654452 1209047 1086677..1086784 1 NC_002971.3 hypothetical protein 1086784 1209047 CBU_1145 Coxiella burnetii RSA 493 hypothetical protein NP_820144.1 1086677 D 227377 CDS NP_820145.2 215919120 1209049 1090311..1091426 1 NC_002971.3 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1091426 mnmA 1209049 mnmA Coxiella burnetii RSA 493 tRNA-specific 2-thiouridylase MnmA NP_820145.2 1090311 D 227377 CDS NP_820146.1 29654454 1209050 1091438..1094911 1 NC_002971.3 transcription-repair coupling factor 1094911 mfd 1209050 mfd Coxiella burnetii RSA 493 transcription-repair coupling factor NP_820146.1 1091438 D 227377 CDS NP_820149.2 215919121 1209053 complement(1095758..1096495) 1 NC_002971.3 HAD superfamily hydrolase 1096495 1209053 CBU_1151 Coxiella burnetii RSA 493 HAD superfamily hydrolase NP_820149.2 1095758 R 227377 CDS NP_820150.1 29654458 1209054 1096631..1098022 1 NC_002971.3 anthranilate synthase component I 1098022 trpE 1209054 trpE Coxiella burnetii RSA 493 anthranilate synthase component I NP_820150.1 1096631 D 227377 CDS NP_820151.1 29654459 1209056 1099660..1100433 1 NC_002971.3 indole-3-glycerol phosphate synthase 1100433 trpC 1209056 trpC Coxiella burnetii RSA 493 indole-3-glycerol phosphate synthase NP_820151.1 1099660 D 227377 CDS NP_820152.1 29654460 1209057 1100426..1102228 1 NC_002971.3 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate; catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta 1102228 trpBF 1209057 trpBF Coxiella burnetii RSA 493 bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta NP_820152.1 1100426 D 227377 CDS NP_820153.1 29654461 1209058 1102245..1103048 1 NC_002971.3 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1103048 trpA 1209058 trpA Coxiella burnetii RSA 493 tryptophan synthase subunit alpha NP_820153.1 1102245 D 227377 CDS NP_820154.1 29654462 1209059 complement(1103045..1103746) 1 NC_002971.3 lipoprotein 1103746 1209059 CBU_1157 Coxiella burnetii RSA 493 lipoprotein NP_820154.1 1103045 R 227377 CDS NP_820155.1 29654463 1209060 1103871..1105238 1 NC_002971.3 sterol delta-7-reductase 1105238 1209060 CBU_1158 Coxiella burnetii RSA 493 sterol delta-7-reductase NP_820155.1 1103871 D 227377 CDS NP_820157.2 570699731 1209062 1105298..1106857 1 NC_002971.3 hypothetical protein 1106857 1209062 CBU_1160a Coxiella burnetii RSA 493 hypothetical protein NP_820157.2 1105298 D 227377 CDS NP_820158.1 29654466 1209063 1106926..1107018 1 NC_002971.3 hypothetical protein 1107018 1209063 CBU_1161 Coxiella burnetii RSA 493 hypothetical protein NP_820158.1 1106926 D 227377 CDS NP_820159.1 29654467 1209064 complement(1107357..1108688) 1 NC_002971.3 MFS superfamily transporter 1108688 1209064 CBU_1162 Coxiella burnetii RSA 493 MFS superfamily transporter NP_820159.1 1107357 R 227377 CDS NP_820166.1 29654474 1209072 1112550..1113005 1 NC_002971.3 heat shock protein 20 1113005 1209072 CBU_1169 Coxiella burnetii RSA 493 heat shock protein 20 NP_820166.1 1112550 D 227377 CDS NP_820167.1 29654475 1209073 1113154..1113360 1 NC_002971.3 hypothetical protein 1113360 1209073 CBU_1170 Coxiella burnetii RSA 493 hypothetical protein NP_820167.1 1113154 D 227377 CDS NP_820168.2 215919122 1209074 complement(1113434..1113886) 1 NC_002971.3 hypothetical protein 1113886 1209074 CBU_1171 Coxiella burnetii RSA 493 hypothetical protein NP_820168.2 1113434 R 227377 CDS NP_820169.1 29654477 1209076 1115568..1115936 1 NC_002971.3 hypothetical protein 1115936 1209076 CBU_1173 Coxiella burnetii RSA 493 hypothetical protein NP_820169.1 1115568 D 227377 CDS NP_820170.1 29654478 1209078 complement(1116436..1117749) 1 NC_002971.3 hypothetical protein 1117749 1209078 CBU_1175 Coxiella burnetii RSA 493 hypothetical protein NP_820170.1 1116436 R 227377 CDS NP_820171.1 29654479 1209079 1117997..1119415 1 NC_002971.3 deoxyribodipyrimidine photolyase 1119415 phrB 1209079 phrB Coxiella burnetii RSA 493 deoxyribodipyrimidine photolyase NP_820171.1 1117997 D 227377 CDS NP_820172.1 29654480 1209080 complement(1119443..1119625) 1 NC_002971.3 hypothetical protein 1119625 1209080 CBU_1177 Coxiella burnetii RSA 493 hypothetical protein NP_820172.1 1119443 R 227377 CDS NP_820173.1 29654481 1209081 1120012..1121145 1 NC_002971.3 hypothetical protein 1121145 1209081 CBU_1178 Coxiella burnetii RSA 493 hypothetical protein NP_820173.1 1120012 D 227377 CDS NP_820174.1 29654482 1209082 1121188..1122384 1 NC_002971.3 Bcr/CflA subfamily drug resistance transporter 1122384 1209082 CBU_1179 Coxiella burnetii RSA 493 Bcr/CflA subfamily drug resistance transporter NP_820174.1 1121188 D 227377 CDS NP_820175.1 29654483 1209083 complement(1122404..1122535) 1 NC_002971.3 hypothetical protein 1122535 1209083 CBU_1180 Coxiella burnetii RSA 493 hypothetical protein NP_820175.1 1122404 R 227377 CDS NP_820176.1 29654484 1209084 complement(1122574..1123752) 1 NC_002971.3 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1123752 thiI 1209084 thiI Coxiella burnetii RSA 493 thiamine biosynthesis protein ThiI NP_820176.1 1122574 R 227377 CDS NP_820177.1 29654485 1209085 complement(1123753..1124895) 1 NC_002971.3 class V aminotransferase 1124895 iscS 1209085 iscS Coxiella burnetii RSA 493 class V aminotransferase NP_820177.1 1123753 R 227377 CDS NP_820178.2 215919123 1209086 1125097..1125450 1 NC_002971.3 nucleic acid binding domain-containing protein 1125450 1209086 CBU_1183 Coxiella burnetii RSA 493 nucleic acid binding domain-containing protein NP_820178.2 1125097 D 227377 CDS NP_820179.1 29654487 1209087 complement(1125521..1126249) 1 NC_002971.3 acyltransferase 1126249 1209087 CBU_1184 Coxiella burnetii RSA 493 acyltransferase NP_820179.1 1125521 R 227377 CDS NP_820180.1 29654488 1209088 complement(1126352..1128181) 1 NC_002971.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1128181 uvrC 1209088 uvrC Coxiella burnetii RSA 493 excinuclease ABC subunit C NP_820180.1 1126352 R 227377 CDS NP_820181.2 215919124 1209090 1128693..1129787 1 NC_002971.3 IS1111A transposase 1129787 1209090 CBU_1186 Coxiella burnetii RSA 493 IS1111A transposase NP_820181.2 1128693 D 227377 CDS YP_002332987.1 215919125 7065915 complement(1129784..1130056) 1 NC_002971.3 hypothetical protein 1130056 7065915 CBU_1186a Coxiella burnetii RSA 493 hypothetical protein YP_002332987.1 1129784 R 227377 CDS YP_002332988.1 215919126 7065972 1130104..1130247 1 NC_002971.3 hypothetical protein 1130247 7065972 CBU_1186b Coxiella burnetii RSA 493 hypothetical protein YP_002332988.1 1130104 D 227377 CDS NP_820182.1 29654490 1209091 1130465..1131112 1 NC_002971.3 hypothetical protein 1131112 1209091 CBU_1187 Coxiella burnetii RSA 493 hypothetical protein NP_820182.1 1130465 D 227377 CDS NP_820183.1 29654491 1209092 complement(1131109..1132380) 1 NC_002971.3 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'; seryl-tRNA synthetase 1132380 serS 1209092 serS Coxiella burnetii RSA 493 seryl-tRNA synthetase NP_820183.1 1131109 R 227377 CDS NP_820184.4 229220692 1209093 complement(1132456..1133778) 1 NC_002971.3 recombination factor protein RarA 1133778 1209093 CBU_1189 Coxiella burnetii RSA 493 recombination factor protein RarA NP_820184.4 1132456 R 227377 CDS NP_820185.1 29654493 1209094 complement(1133762..1134397) 1 NC_002971.3 outer-membrane lipoproteins carrier protein 1134397 lolA 1209094 lolA Coxiella burnetii RSA 493 outer-membrane lipoproteins carrier protein NP_820185.1 1133762 R 227377 CDS NP_820186.2 215919128 1209095 complement(1134409..1136766) 1 NC_002971.3 DNA translocase FtsK 1136766 ftsK 1209095 ftsK Coxiella burnetii RSA 493 DNA translocase FtsK NP_820186.2 1134409 R 227377 CDS NP_820188.1 29654496 1209097 1136869..1137831 1 NC_002971.3 thioredoxin-disulfide reductase 1137831 trxB 1209097 trxB Coxiella burnetii RSA 493 thioredoxin-disulfide reductase NP_820188.1 1136869 D 227377 CDS NP_820189.1 29654497 1209098 1137857..1139293 1 NC_002971.3 hypothetical protein 1139293 1209098 CBU_1194 Coxiella burnetii RSA 493 hypothetical protein NP_820189.1 1137857 D 227377 CDS NP_820190.1 29654498 1209099 1139355..1139606 1 NC_002971.3 'stimulates the activities of the other two initiation factors, IF-2 and IF-3'; translation initiation factor IF-1 1139606 infA 1209099 infA Coxiella burnetii RSA 493 translation initiation factor IF-1 NP_820190.1 1139355 D 227377 CDS NP_820191.1 29654499 1209100 complement(1139669..1141930) 1 NC_002971.3 ATP-dependent Clp protease ATP-binding subunit ClpA 1141930 clpA 1209100 clpA Coxiella burnetii RSA 493 ATP-dependent Clp protease ATP-binding subunit ClpA NP_820191.1 1139669 R 227377 CDS NP_820192.1 29654500 1209101 1141963..1142163 1 NC_002971.3 hypothetical protein 1142163 1209101 CBU_1197 Coxiella burnetii RSA 493 hypothetical protein NP_820192.1 1141963 D 227377 CDS NP_820193.1 29654501 1209102 1142253..1142789 1 NC_002971.3 hypothetical protein 1142789 1209102 CBU_1198 Coxiella burnetii RSA 493 hypothetical protein NP_820193.1 1142253 D 227377 CDS NP_820194.1 29654502 1209103 1142823..1142921 1 NC_002971.3 hypothetical protein 1142921 1209103 CBU_1199 Coxiella burnetii RSA 493 hypothetical protein NP_820194.1 1142823 D 227377 CDS NP_820195.2 215919129 1209104 complement(1142958..1144244) 1 NC_002971.3 NADP; isocitrate dehydrogenase 1144244 icd 1209104 icd Coxiella burnetii RSA 493 isocitrate dehydrogenase NP_820195.2 1142958 R 227377 CDS NP_820196.1 29654504 1209105 complement(1144288..1145319) 1 NC_002971.3 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1145319 queA 1209105 queA Coxiella burnetii RSA 493 S-adenosylmethionine--tRNA ribosyltransferase-isomerase NP_820196.1 1144288 R 227377 CDS NP_820197.1 29654505 1209106 1145436..1146287 1 NC_002971.3 hypothetical protein 1146287 1209106 CBU_1202 Coxiella burnetii RSA 493 hypothetical protein NP_820197.1 1145436 D 227377 CDS NP_820198.1 29654506 1209107 1146351..1148003 1 NC_002971.3 glutamate synthase domain protein 1148003 1209107 CBU_1203 Coxiella burnetii RSA 493 glutamate synthase domain protein NP_820198.1 1146351 D 227377 CDS NP_820199.2 215919130 1209108 1148007..1149383 1 NC_002971.3 NADP+; succinate-semialdehyde dehydrogenase 1149383 1209108 CBU_1204 Coxiella burnetii RSA 493 succinate-semialdehyde dehydrogenase NP_820199.2 1148007 D 227377 CDS NP_820201.2 215919131 1209110 complement(1149484..1150863) 1 NC_002971.3 delta(24(24(1)))-sterol reductase 1150863 1209110 CBU_1206 Coxiella burnetii RSA 493 delta(24(24(1)))-sterol reductase NP_820201.2 1149484 R 227377 CDS NP_820202.1 29654510 1209111 complement(1150881..1151033) 1 NC_002971.3 hypothetical protein 1151033 1209111 CBU_1207 Coxiella burnetii RSA 493 hypothetical protein NP_820202.1 1150881 R 227377 CDS NP_820203.1 29654511 1209112 1151258..1152496 1 NC_002971.3 major facilitator transporter 1152496 1209112 CBU_1208 Coxiella burnetii RSA 493 major facilitator transporter NP_820203.1 1151258 D 227377 CDS NP_820204.2 215919132 1209113 complement(1152509..1154050) 1 NC_002971.3 hypothetical protein 1154050 1209113 CBU_1209 Coxiella burnetii RSA 493 hypothetical protein NP_820204.2 1152509 R 227377 CDS YP_002332989.1 215919133 7065983 1156864..1157028 1 NC_002971.3 hypothetical protein 1157028 7065983 CBU_1212a Coxiella burnetii RSA 493 hypothetical protein YP_002332989.1 1156864 D 227377 CDS NP_820208.1 29654516 1209117 1157067..1159040 1 NC_002971.3 ankyrin repeat-containing protein 1159040 1209117 CBU_1213 Coxiella burnetii RSA 493 ankyrin repeat-containing protein NP_820208.1 1157067 D 227377 CDS NP_820209.1 29654517 1209118 1159107..1159244 1 NC_002971.3 hypothetical protein 1159244 1209118 CBU_1214 Coxiella burnetii RSA 493 hypothetical protein NP_820209.1 1159107 D 227377 CDS YP_002332990.1 215919134 7065889 complement(1161192..1161326) 1 NC_002971.3 hypothetical protein 1161326 7065889 CBU_1216a Coxiella burnetii RSA 493 hypothetical protein YP_002332990.1 1161192 R 227377 CDS NP_820212.1 29654520 1209121 1161602..1163095 1 NC_002971.3 hypothetical protein 1163095 1209121 CBU_1217 Coxiella burnetii RSA 493 hypothetical protein NP_820212.1 1161602 D 227377 CDS YP_002332991.1 215919135 1209123 1163350..1164444 1 NC_002971.3 transposase 1164444 1209123 CBU_1217a Coxiella burnetii RSA 493 transposase YP_002332991.1 1163350 D 227377 CDS NP_820214.1 29654522 1209124 complement(1164798..1165916) 1 NC_002971.3 hypothetical protein 1165916 1209124 CBU_1219 Coxiella burnetii RSA 493 hypothetical protein NP_820214.1 1164798 R 227377 CDS NP_820215.1 29654523 1209125 complement(1165917..1166639) 1 NC_002971.3 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1166639 purC 1209125 purC Coxiella burnetii RSA 493 phosphoribosylaminoimidazole-succinocarboxamide synthase NP_820215.1 1165917 R 227377 CDS NP_820216.1 29654524 1209126 complement(1166639..1167232) 1 NC_002971.3 lipoprotein 1167232 1209126 CBU_1221 Coxiella burnetii RSA 493 lipoprotein NP_820216.1 1166639 R 227377 CDS NP_820217.2 215919136 1209127 complement(1167249..1168142) 1 NC_002971.3 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1168142 dapA 1209127 dapA Coxiella burnetii RSA 493 dihydrodipicolinate synthase NP_820217.2 1167249 R 227377 CDS NP_820218.1 29654526 1209128 complement(1168355..1169284) 1 NC_002971.3 2-dehydro-3-deoxygluconokinase 1169284 kdgK 1209128 kdgK Coxiella burnetii RSA 493 2-dehydro-3-deoxygluconokinase NP_820218.1 1168355 R 227377 CDS NP_820219.2 215919137 1209129 1169324..1170604 1 NC_002971.3 RmuC family protein 1170604 1209129 CBU_1224 Coxiella burnetii RSA 493 RmuC family protein NP_820219.2 1169324 D 227377 CDS YP_002332992.1 215919138 7065926 complement(1170709..1170906) 1 NC_002971.3 hypothetical protein 1170906 7065926 CBU_1224a Coxiella burnetii RSA 493 hypothetical protein YP_002332992.1 1170709 R 227377 CDS NP_820220.2 215919139 1209130 complement(1171017..1171925) 1 NC_002971.3 catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide; haloalkane dehalogenase 1171925 1209130 CBU_1225 Coxiella burnetii RSA 493 haloalkane dehalogenase NP_820220.2 1171017 R 227377 CDS NP_820221.2 215919140 1209131 complement(1171922..1176802) 1 NC_002971.3 glutamate dehydrogenase 1176802 1209131 CBU_1226 Coxiella burnetii RSA 493 glutamate dehydrogenase NP_820221.2 1171922 R 227377 CDS NP_820222.2 215919141 1209132 1176990..1177688 1 NC_002971.3 transcriptional regulatory protein 1177688 qseB 1209132 qseB Coxiella burnetii RSA 493 transcriptional regulatory protein NP_820222.2 1176990 D 227377 CDS NP_820223.1 29654531 1209133 1177685..1179121 1 NC_002971.3 sensor protein qseC 1179121 qseC 1209133 qseC Coxiella burnetii RSA 493 sensor protein qseC NP_820223.1 1177685 D 227377 CDS NP_820224.1 29654532 1209134 1179351..1181939 1 NC_002971.3 ATP-dependent nuclease subunit B 1181939 1209134 CBU_1229 Coxiella burnetii RSA 493 ATP-dependent nuclease subunit B NP_820224.1 1179351 D 227377 CDS NP_820225.1 29654533 1209135 1181936..1185268 1 NC_002971.3 ATP-dependent nuclease subunit A 1185268 1209135 CBU_1230 Coxiella burnetii RSA 493 ATP-dependent nuclease subunit A NP_820225.1 1181936 D 227377 CDS NP_820226.2 215919142 1209136 complement(1185414..1186112) 1 NC_002971.3 hypothetical protein 1186112 1209136 CBU_1231 Coxiella burnetii RSA 493 hypothetical protein NP_820226.2 1185414 R 227377 CDS NP_820228.2 215919143 1209138 1186391..1187293 1 NC_002971.3 5'-nucleotidase 1187293 1209138 CBU_1233 Coxiella burnetii RSA 493 5'-nucleotidase NP_820228.2 1186391 D 227377 CDS NP_820229.2 215919144 1209139 1187356..1188642 1 NC_002971.3 ATPase 1188642 1209139 CBU_1234 Coxiella burnetii RSA 493 ATPase NP_820229.2 1187356 D 227377 CDS NP_820230.1 29654538 1209140 1188801..1189352 1 NC_002971.3 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1189352 orn 1209140 orn Coxiella burnetii RSA 493 oligoribonuclease NP_820230.1 1188801 D 227377 CDS NP_820231.1 29654539 1209141 1189529..1189621 1 NC_002971.3 hypothetical protein 1189621 1209141 CBU_1236 Coxiella burnetii RSA 493 hypothetical protein NP_820231.1 1189529 D 227377 CDS NP_820232.2 215919145 1209142 complement(1189802..1190194) 1 NC_002971.3 twitching motility protein PilT 1190194 1209142 CBU_1237 Coxiella burnetii RSA 493 twitching motility protein PilT NP_820232.2 1189802 R 227377 CDS NP_820233.1 29654541 1209143 complement(1190197..1190451) 1 NC_002971.3 CopG family transcriptional regulator 1190451 1209143 CBU_1238 Coxiella burnetii RSA 493 CopG family transcriptional regulator NP_820233.1 1190197 R 227377 CDS NP_820234.1 29654542 1209144 1190596..1191177 1 NC_002971.3 hypothetical protein 1191177 1209144 CBU_1239 Coxiella burnetii RSA 493 hypothetical protein NP_820234.1 1190596 D 227377 CDS NP_820235.1 29654543 1209145 complement(1191253..1192272) 1 NC_002971.3 'in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity'; DNA-binding/iron metalloprotein/AP endonuclease 1192272 gcp 1209145 gcp Coxiella burnetii RSA 493 DNA-binding/iron metalloprotein/AP endonuclease NP_820235.1 1191253 R 227377 CDS NP_820236.1 29654544 1209146 complement(1192281..1193267) 1 NC_002971.3 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 1193267 mdh 1209146 mdh Coxiella burnetii RSA 493 malate dehydrogenase NP_820236.1 1192281 R 227377 CDS NP_820237.1 29654545 1209147 complement(1193462..1194688) 1 NC_002971.3 long-chain fatty acid transport protein 1194688 1209147 CBU_1242 Coxiella burnetii RSA 493 long-chain fatty acid transport protein NP_820237.1 1193462 R 227377 CDS NP_820238.1 29654546 1209148 1194822..1196066 1 NC_002971.3 exodeoxyribonuclease VII large subunit 1196066 xseA 1209148 xseA Coxiella burnetii RSA 493 exodeoxyribonuclease VII large subunit NP_820238.1 1194822 D 227377 CDS NP_820239.1 29654547 1209149 1196063..1197598 1 NC_002971.3 EmrB/QacA family drug resistance transporter 1197598 1209149 CBU_1244 Coxiella burnetii RSA 493 EmrB/QacA family drug resistance transporter NP_820239.1 1196063 D 227377 CDS NP_820240.1 29654548 1209150 complement(1197738..1199069) 1 NC_002971.3 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1199069 engA 1209150 engA Coxiella burnetii RSA 493 GTP-binding protein EngA NP_820240.1 1197738 R 227377 CDS NP_820242.1 29654550 1209152 complement(1199307..1199927) 1 NC_002971.3 hypothetical protein 1199927 1209152 CBU_1247 Coxiella burnetii RSA 493 hypothetical protein NP_820242.1 1199307 R 227377 CDS NP_820243.1 29654551 1209153 complement(1199950..1201215) 1 NC_002971.3 'catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG'; histidyl-tRNA synthetase 1201215 hisS 1209153 hisS Coxiella burnetii RSA 493 histidyl-tRNA synthetase NP_820243.1 1199950 R 227377 CDS NP_820244.1 29654552 1209154 complement(1201212..1201823) 1 NC_002971.3 DNA-binding protein 1201823 1209154 CBU_1249 Coxiella burnetii RSA 493 DNA-binding protein NP_820244.1 1201212 R 227377 CDS NP_820245.1 29654553 1209155 complement(1201960..1202100) 1 NC_002971.3 hypothetical protein 1202100 1209155 CBU_1250 Coxiella burnetii RSA 493 hypothetical protein NP_820245.1 1201960 R 227377 CDS NP_820246.1 29654554 1209157 complement(1202950..1204062) 1 NC_002971.3 radical SAM protein 1204062 1209157 CBU_1252 Coxiella burnetii RSA 493 radical SAM protein NP_820246.1 1202950 R 227377 CDS YP_008992031.1 570699733 18126242 1204287..1204724 1 NC_002971.3 hypothetical protein 1204724 18126242 CBU_1253a Coxiella burnetii RSA 493 hypothetical protein YP_008992031.1 1204287 D 227377 CDS YP_008992032.1 570699734 18126245 1204956..1206482 1 NC_002971.3 ankyrin 1206482 18126245 CBU_1253b Coxiella burnetii RSA 493 ankyrin YP_008992032.1 1204956 D 227377 CDS NP_820249.1 29654557 1209160 complement(1206825..1207628) 1 NC_002971.3 polyprenyl synthetase 1207628 1209160 CBU_1255 Coxiella burnetii RSA 493 polyprenyl synthetase NP_820249.1 1206825 R 227377 CDS NP_820250.1 29654558 1209161 1207660..1207776 1 NC_002971.3 hypothetical protein 1207776 1209161 CBU_1256 Coxiella burnetii RSA 493 hypothetical protein NP_820250.1 1207660 D 227377 CDS NP_820251.1 29654559 1209162 1207769..1208173 1 NC_002971.3 hypothetical protein 1208173 1209162 CBU_1257 Coxiella burnetii RSA 493 hypothetical protein NP_820251.1 1207769 D 227377 CDS NP_820252.1 29654560 1209163 complement(1208159..1208593) 1 NC_002971.3 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1208593 ndk 1209163 ndk Coxiella burnetii RSA 493 nucleoside diphosphate kinase NP_820252.1 1208159 R 227377 CDS NP_820253.1 29654561 1209164 1208729..1210327 1 NC_002971.3 Na+/H+ antiporter 1210327 nhaP.1 1209164 nhaP.1 Coxiella burnetii RSA 493 Na+/H+ antiporter NP_820253.1 1208729 D 227377 CDS NP_820254.1 29654562 1209165 1210764..1211510 1 NC_002971.3 OmpA-like transmembrane domain-containing protein 1211510 1209165 CBU_1260 Coxiella burnetii RSA 493 OmpA-like transmembrane domain-containing protein NP_820254.1 1210764 D 227377 CDS NP_820255.1 29654563 1209166 1211608..1212864 1 NC_002971.3 D-alanyl-D-alanine serine-type carboxypeptidase 1212864 1209166 CBU_1261 Coxiella burnetii RSA 493 D-alanyl-D-alanine serine-type carboxypeptidase NP_820255.1 1211608 D 227377 CDS NP_820256.1 29654564 1209167 1212861..1213124 1 NC_002971.3 hypothetical protein 1213124 1209167 CBU_1262 Coxiella burnetii RSA 493 hypothetical protein NP_820256.1 1212861 D 227377 CDS NP_820257.1 29654565 1209168 1213148..1213534 1 NC_002971.3 hypothetical protein 1213534 1209168 CBU_1263 Coxiella burnetii RSA 493 hypothetical protein NP_820257.1 1213148 D 227377 CDS NP_820259.1 29654567 1209170 1214140..1214868 1 NC_002971.3 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1214868 lipB 1209170 lipB Coxiella burnetii RSA 493 lipoate-protein ligase B NP_820259.1 1214140 D 227377 CDS NP_820260.1 29654568 1209171 1214798..1215745 1 NC_002971.3 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1215745 lipA 1209171 lipA Coxiella burnetii RSA 493 lipoyl synthase NP_820260.1 1214798 D 227377 CDS NP_820261.1 29654569 1209172 1215856..1217904 1 NC_002971.3 DedA/PAP2 domain-containing protein 1217904 1209172 CBU_1267 Coxiella burnetii RSA 493 DedA/PAP2 domain-containing protein NP_820261.1 1215856 D 227377 CDS YP_002332993.1 215919146 7065864 1217948..1218040 1 NC_002971.3 ScvA 1218040 scvA 7065864 scvA Coxiella burnetii RSA 493 ScvA YP_002332993.1 1217948 D 227377 CDS NP_820262.2 215919147 1209173 complement(1218096..1219169) 1 NC_002971.3 pyridine nucleotide-disulfide oxidoreductase 1219169 1209173 CBU_1268 Coxiella burnetii RSA 493 pyridine nucleotide-disulfide oxidoreductase NP_820262.2 1218096 R 227377 CDS NP_820263.1 29654571 1209174 complement(1219176..1219667) 1 NC_002971.3 thioesterase 1219667 1209174 CBU_1269 Coxiella burnetii RSA 493 thioesterase NP_820263.1 1219176 R 227377 CDS YP_002332994.1 215919148 7065888 1219705..1220094 1 NC_002971.3 hypothetical protein 1220094 7065888 CBU_1269a Coxiella burnetii RSA 493 hypothetical protein YP_002332994.1 1219705 D 227377 CDS NP_820264.2 215919149 1209175 complement(1220091..1221185) 1 NC_002971.3 IS1111A transposase 1221185 1209175 CBU_1270 Coxiella burnetii RSA 493 IS1111A transposase NP_820264.2 1220091 R 227377 CDS NP_820265.1 29654573 1209177 complement(1222861..1222977) 1 NC_002971.3 hypothetical protein 1222977 1209177 CBU_1272 Coxiella burnetii RSA 493 hypothetical protein NP_820265.1 1222861 R 227377 CDS NP_820266.1 29654574 1209178 1223250..1224512 1 NC_002971.3 'catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis'; 6-phosphofructokinase 1224512 1209178 CBU_1273 Coxiella burnetii RSA 493 6-phosphofructokinase NP_820266.1 1223250 D 227377 CDS NP_820267.1 29654575 1209179 complement(1224514..1224996) 1 NC_002971.3 hypothetical protein 1224996 1209179 CBU_1274 Coxiella burnetii RSA 493 hypothetical protein NP_820267.1 1224514 R 227377 CDS NP_820268.1 29654576 1209180 complement(1224990..1226198) 1 NC_002971.3 mandelate racemase 1226198 RspA 1209180 RspA Coxiella burnetii RSA 493 mandelate racemase NP_820268.1 1224990 R 227377 CDS NP_820269.2 215919150 1209181 complement(1226229..1227035) 1 NC_002971.3 short chain dehydrogenase/reductase oxidoreductase 1227035 1209181 CBU_1276 Coxiella burnetii RSA 493 short chain dehydrogenase/reductase oxidoreductase NP_820269.2 1226229 R 227377 CDS NP_820270.2 215919151 1209182 1227098..1227805 1 NC_002971.3 2-dehydro-3-deoxyphosphooctonate aldolase 1227805 eda 1209182 eda Coxiella burnetii RSA 493 2-dehydro-3-deoxyphosphooctonate aldolase NP_820270.2 1227098 D 227377 CDS NP_820271.1 29654579 1209183 1227816..1228373 1 NC_002971.3 antioxidant, AhpC/TSA family 1228373 1209183 CBU_1278 Coxiella burnetii RSA 493 antioxidant, AhpC/TSA family NP_820271.1 1227816 D 227377 CDS NP_820272.1 29654580 1209184 1228361..1228963 1 NC_002971.3 exopolysaccharide transporter 1228963 exoD 1209184 exoD Coxiella burnetii RSA 493 exopolysaccharide transporter NP_820272.1 1228361 D 227377 CDS YP_002332995.1 215919152 7065973 1229009..1229131 1 NC_002971.3 hypothetical protein 1229131 7065973 CBU_1279a Coxiella burnetii RSA 493 hypothetical protein YP_002332995.1 1229009 D 227377 CDS NP_820273.2 215919153 1209185 complement(1229297..1229818) 1 NC_002971.3 transcription elongation factor 1229818 greA 1209185 greA Coxiella burnetii RSA 493 transcription elongation factor NP_820273.2 1229297 R 227377 CDS YP_002332996.1 215919154 7065925 1230040..1230279 1 NC_002971.3 hypothetical protein 1230279 7065925 CBU_1280a Coxiella burnetii RSA 493 hypothetical protein YP_002332996.1 1230040 D 227377 CDS NP_820274.1 29654582 1209186 complement(1230329..1233550) 1 NC_002971.3 carbamoyl-phosphate synthase large subunit 1233550 carB 1209186 carB Coxiella burnetii RSA 493 carbamoyl-phosphate synthase large subunit NP_820274.1 1230329 R 227377 CDS NP_820275.2 215919155 1209187 complement(1233632..1234840) 1 NC_002971.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1234840 carA 1209187 carA Coxiella burnetii RSA 493 carbamoyl phosphate synthase small subunit NP_820275.2 1233632 R 227377 CDS NP_820276.1 29654584 1209189 1236614..1237924 1 NC_002971.3 ATPase 1237924 1209189 CBU_1284 Coxiella burnetii RSA 493 ATPase NP_820276.1 1236614 D 227377 CDS NP_820277.1 29654585 1209190 1237921..1239279 1 NC_002971.3 multidrug resistance protein B 1239279 1209190 CBU_1285 Coxiella burnetii RSA 493 multidrug resistance protein B NP_820277.1 1237921 D 227377 CDS NP_820278.1 29654586 1209191 1239350..1240732 1 NC_002971.3 ATPase 1240732 1209191 CBU_1286 Coxiella burnetii RSA 493 ATPase NP_820278.1 1239350 D 227377 CDS NP_820281.1 29654589 1209194 complement(1242652..1243776) 1 NC_002971.3 'chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion'; molecular chaperone DnaJ 1243776 dnaJ 1209194 dnaJ Coxiella burnetii RSA 493 molecular chaperone DnaJ NP_820281.1 1242652 R 227377 CDS NP_820282.1 29654590 1209195 complement(1243919..1245889) 1 NC_002971.3 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1245889 dnaK 1209195 dnaK Coxiella burnetii RSA 493 molecular chaperone DnaK NP_820282.1 1243919 R 227377 CDS NP_820283.1 29654591 1209196 1246055..1246648 1 NC_002971.3 biotin-requiring enzyme subunit 1246648 1209196 CBU_1291 Coxiella burnetii RSA 493 biotin-requiring enzyme subunit NP_820283.1 1246055 D 227377 CDS NP_820284.1 29654592 1209197 1246651..1248048 1 NC_002971.3 ankyrin repeat-containing protein 1248048 1209197 CBU_1292 Coxiella burnetii RSA 493 ankyrin repeat-containing protein NP_820284.1 1246651 D 227377 CDS NP_820285.2 215919156 1209198 complement(1248178..1248804) 1 NC_002971.3 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1248804 grpE 1209198 grpE Coxiella burnetii RSA 493 heat shock protein GrpE NP_820285.2 1248178 R 227377 CDS NP_820286.1 29654594 1209199 complement(1248859..1249236) 1 NC_002971.3 twitching motility protein PilT 1249236 1209199 CBU_1294 Coxiella burnetii RSA 493 twitching motility protein PilT NP_820286.1 1248859 R 227377 CDS NP_820287.1 29654595 1209200 complement(1249226..1249555) 1 NC_002971.3 hypothetical protein 1249555 1209200 CBU_1295 Coxiella burnetii RSA 493 hypothetical protein NP_820287.1 1249226 R 227377 CDS NP_820288.1 29654596 1209201 1249565..1250464 1 NC_002971.3 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1250464 ppnK 1209201 ppnK Coxiella burnetii RSA 493 inorganic polyphosphate/ATP-NAD kinase NP_820288.1 1249565 D 227377 CDS NP_820289.1 29654597 1209202 1250469..1252139 1 NC_002971.3 DNA repair protein 1252139 recN 1209202 recN Coxiella burnetii RSA 493 DNA repair protein NP_820289.1 1250469 D 227377 CDS NP_820292.1 29654600 1209205 complement(1254274..1254621) 1 NC_002971.3 hypothetical protein 1254621 1209205 CBU_1300 Coxiella burnetii RSA 493 hypothetical protein NP_820292.1 1254274 R 227377 CDS NP_820293.1 29654601 1209206 complement(1254632..1255099) 1 NC_002971.3 ferric uptake regulation protein 1255099 fur 1209206 fur Coxiella burnetii RSA 493 ferric uptake regulation protein NP_820293.1 1254632 R 227377 CDS NP_820294.1 29654602 1209207 1255226..1255606 1 NC_002971.3 hypothetical protein 1255606 omlA 1209207 omlA Coxiella burnetii RSA 493 hypothetical protein NP_820294.1 1255226 D 227377 CDS NP_820295.1 29654603 1209208 complement(1255550..1255855) 1 NC_002971.3 hypothetical protein 1255855 1209208 CBU_1303 Coxiella burnetii RSA 493 hypothetical protein NP_820295.1 1255550 R 227377 CDS NP_820296.1 29654604 1209209 complement(1255852..1256292) 1 NC_002971.3 polyketide cyclase/dehydrase 1256292 1209209 CBU_1304 Coxiella burnetii RSA 493 polyketide cyclase/dehydrase NP_820296.1 1255852 R 227377 CDS NP_820297.1 29654605 1209210 1256319..1256798 1 NC_002971.3 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1256798 smpB 1209210 smpB Coxiella burnetii RSA 493 SsrA-binding protein NP_820297.1 1256319 D 227377 CDS NP_820298.1 29654606 1209211 1256791..1257645 1 NC_002971.3 'this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae'; bifunctional methionine sulfoxide reductase B/A protein 1257645 msrA 1209211 msrA Coxiella burnetii RSA 493 bifunctional methionine sulfoxide reductase B/A protein NP_820298.1 1256791 D 227377 CDS NP_820299.2 215919157 1209212 complement(1257646..1258062) 1 NC_002971.3 hypothetical protein 1258062 1209212 CBU_1307 Coxiella burnetii RSA 493 hypothetical protein NP_820299.2 1257646 R 227377 CDS NP_820300.1 29654608 1209213 1258425..1259090 1 NC_002971.3 phosphohydrolase 1259090 1209213 CBU_1308 Coxiella burnetii RSA 493 phosphohydrolase NP_820300.1 1258425 D 227377 CDS YP_008992033.1 570699735 7065890 complement(1259932..1260480) 1 NC_002971.3 gramicidin synthetase 1260480 7065890 CBU_1309a Coxiella burnetii RSA 493 gramicidin synthetase YP_008992033.1 1259932 R 227377 CDS NP_820301.1 29654609 1209215 complement(1260734..1260838) 1 NC_002971.3 hypothetical protein 1260838 1209215 CBU_1310 Coxiella burnetii RSA 493 hypothetical protein NP_820301.1 1260734 R 227377 CDS NP_820302.1 29654610 1209216 complement(1260865..1263306) 1 NC_002971.3 hypothetical protein 1263306 1209216 CBU_1311 Coxiella burnetii RSA 493 hypothetical protein NP_820302.1 1260865 R 227377 CDS NP_820303.1 29654611 1209217 1263468..1263581 1 NC_002971.3 hypothetical protein 1263581 1209217 CBU_1312 Coxiella burnetii RSA 493 hypothetical protein NP_820303.1 1263468 D 227377 CDS NP_820304.1 29654612 1209218 complement(1263712..1263837) 1 NC_002971.3 hypothetical protein 1263837 1209218 CBU_1313 Coxiella burnetii RSA 493 hypothetical protein NP_820304.1 1263712 R 227377 CDS NP_820305.2 215919158 1209219 complement(1264046..1264690) 1 NC_002971.3 hypothetical protein 1264690 1209219 CBU_1314 Coxiella burnetii RSA 493 hypothetical protein NP_820305.2 1264046 R 227377 CDS YP_008992034.1 570699736 7065879 complement(1265007..1265150) 1 NC_002971.3 acetate--CoA ligase 1265150 7065879 CBU_1315a Coxiella burnetii RSA 493 acetate--CoA ligase YP_008992034.1 1265007 R 227377 CDS NP_820306.1 29654614 1209221 complement(1265383..1265610) 1 NC_002971.3 hypothetical protein 1265610 1209221 CBU_1316 Coxiella burnetii RSA 493 hypothetical protein NP_820306.1 1265383 R 227377 CDS YP_002332997.1 215919159 7065981 1265634..1265741 1 NC_002971.3 hypothetical protein 1265741 7065981 CBU_1316a Coxiella burnetii RSA 493 hypothetical protein YP_002332997.1 1265634 D 227377 CDS NP_820307.1 29654615 1209222 complement(1265765..1265893) 1 NC_002971.3 hypothetical protein 1265893 1209222 CBU_1317 Coxiella burnetii RSA 493 hypothetical protein NP_820307.1 1265765 R 227377 CDS NP_820308.1 29654616 1209223 complement(1266253..1266876) 1 NC_002971.3 hypothetical protein 1266876 1209223 CBU_1318 Coxiella burnetii RSA 493 hypothetical protein NP_820308.1 1266253 R 227377 CDS NP_820309.2 215919160 1209225 complement(1267068..1267403) 1 NC_002971.3 transcriptional regulator domain-containing protein 1267403 1209225 CBU_1319 Coxiella burnetii RSA 493 transcriptional regulator domain-containing protein NP_820309.2 1267068 R 227377 CDS NP_820310.1 29654618 1209226 complement(1267417..1267728) 1 NC_002971.3 'This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control'; integration host factor subunit alpha 1267728 ihfA 1209226 ihfA Coxiella burnetii RSA 493 integration host factor subunit alpha NP_820310.1 1267417 R 227377 CDS NP_820311.1 29654619 1209227 complement(1267733..1270111) 1 NC_002971.3 'catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily'; phenylalanyl-tRNA synthetase subunit beta 1270111 pheT 1209227 pheT Coxiella burnetii RSA 493 phenylalanyl-tRNA synthetase subunit beta NP_820311.1 1267733 R 227377 CDS NP_820312.1 29654620 1209228 complement(1270111..1271097) 1 NC_002971.3 'catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily'; phenylalanyl-tRNA synthetase subunit alpha 1271097 pheS 1209228 pheS Coxiella burnetii RSA 493 phenylalanyl-tRNA synthetase subunit alpha NP_820312.1 1270111 R 227377 CDS NP_820313.1 29654621 1209229 complement(1271174..1271533) 1 NC_002971.3 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1271533 rplT 1209229 rplT Coxiella burnetii RSA 493 50S ribosomal protein L20 NP_820313.1 1271174 R 227377 CDS YP_002332998.1 215919161 7065969 1271991..1272092 1 NC_002971.3 hypothetical protein 1272092 7065969 CBU_1323a Coxiella burnetii RSA 493 hypothetical protein YP_002332998.1 1271991 D 227377 CDS NP_820314.1 29654622 1209230 complement(1272173..1272367) 1 NC_002971.3 50S ribosomal protein L35 1272367 rpmI 1209230 rpmI Coxiella burnetii RSA 493 50S ribosomal protein L35 NP_820314.1 1272173 R 227377 CDS NP_820315.1 29654623 1209231 complement(1272348..1272857) 1 NC_002971.3 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1272857 infC 1209231 infC Coxiella burnetii RSA 493 translation initiation factor IF-3 NP_820315.1 1272348 R 227377 CDS NP_820316.2 215919162 1209232 complement(1272941..1274923) 1 NC_002971.3 'catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)'; threonyl-tRNA synthetase 1274923 thrS 1209232 thrS Coxiella burnetii RSA 493 threonyl-tRNA synthetase NP_820316.2 1272941 R 227377 CDS NP_820318.1 29654626 1209234 1275011..1275283 1 NC_002971.3 hypothetical protein 1275283 1209234 CBU_1328 Coxiella burnetii RSA 493 hypothetical protein NP_820318.1 1275011 D 227377 CDS NP_820319.1 29654627 1209235 complement(1275290..1276360) 1 NC_002971.3 radical SAM superfamily protein 1276360 1209235 CBU_1329 Coxiella burnetii RSA 493 radical SAM superfamily protein NP_820319.1 1275290 R 227377 CDS NP_820320.2 215919163 1209237 1277933..1278310 1 NC_002971.3 hypothetical protein 1278310 1209237 CBU_1331 Coxiella burnetii RSA 493 hypothetical protein NP_820320.2 1277933 D 227377 CDS NP_820321.1 29654629 1209238 1278298..1278450 1 NC_002971.3 hypothetical protein 1278450 1209238 CBU_1332 Coxiella burnetii RSA 493 hypothetical protein NP_820321.1 1278298 D 227377 CDS YP_002332999.1 215919164 7065869 1278374..1278481 1 NC_002971.3 hypothetical protein 1278481 7065869 CBU_1332a Coxiella burnetii RSA 493 hypothetical protein YP_002332999.1 1278374 D 227377 CDS NP_820322.1 29654630 1209239 1278463..1279254 1 NC_002971.3 hypothetical protein 1279254 1209239 CBU_1333 Coxiella burnetii RSA 493 hypothetical protein NP_820322.1 1278463 D 227377 CDS NP_820323.1 29654631 1209240 complement(1279209..1280342) 1 NC_002971.3 hypothetical protein 1280342 1209240 CBU_1334 Coxiella burnetii RSA 493 hypothetical protein NP_820323.1 1279209 R 227377 CDS NP_820324.1 29654632 1209241 1280843..1281991 1 NC_002971.3 cyclin 1281991 1209241 CBU_1335 Coxiella burnetii RSA 493 cyclin NP_820324.1 1280843 D 227377 CDS NP_820325.1 29654633 1209242 complement(1281986..1282903) 1 NC_002971.3 transporter, drug/metabolite exporter family 1282903 1209242 CBU_1336 Coxiella burnetii RSA 493 transporter, drug/metabolite exporter family NP_820325.1 1281986 R 227377 CDS NP_820326.1 29654634 1209243 complement(1283012..1286443) 1 NC_002971.3 DNA polymerase III subunit alpha 1286443 dnaE 1209243 dnaE Coxiella burnetii RSA 493 DNA polymerase III subunit alpha NP_820326.1 1283012 R 227377 CDS NP_820327.2 215919165 1209244 complement(1286445..1287566) 1 NC_002971.3 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1287566 ddl 1209244 ddl Coxiella burnetii RSA 493 D-alanyl-alanine synthetase A NP_820327.2 1286445 R 227377 CDS NP_820328.1 29654636 1209245 complement(1287713..1288321) 1 NC_002971.3 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1288321 rnhB 1209245 rnhB Coxiella burnetii RSA 493 ribonuclease HII NP_820328.1 1287713 R 227377 CDS NP_820329.2 215919166 1209246 complement(1288333..1288629) 1 NC_002971.3 hypothetical protein 1288629 1209246 CBU_1340 Coxiella burnetii RSA 493 hypothetical protein NP_820329.2 1288333 R 227377 CDS NP_820330.1 29654638 1209247 complement(1288616..1290190) 1 NC_002971.3 glutamine-hydrolyzing; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1290190 guaA 1209247 guaA Coxiella burnetii RSA 493 GMP synthase NP_820330.1 1288616 R 227377 CDS NP_820331.1 29654639 1209248 complement(1290227..1291696) 1 NC_002971.3 inosine-5'-monophosphate dehydrogenase 1291696 guaB 1209248 guaB Coxiella burnetii RSA 493 inosine-5'-monophosphate dehydrogenase NP_820331.1 1290227 R 227377 CDS NP_820334.1 29654642 1209251 1293369..1294658 1 NC_002971.3 MFS superfamily transporter 1294658 1209251 CBU_1345 Coxiella burnetii RSA 493 MFS superfamily transporter NP_820334.1 1293369 D 227377 CDS NP_820335.2 215919167 1209252 1294909..1296291 1 NC_002971.3 trehalase 1296291 1209252 CBU_1346 Coxiella burnetii RSA 493 trehalase NP_820335.2 1294909 D 227377 CDS NP_820336.1 29654644 1209253 complement(1296202..1297626) 1 NC_002971.3 amino acid permease 1297626 1209253 CBU_1347 Coxiella burnetii RSA 493 amino acid permease NP_820336.1 1296202 R 227377 CDS NP_820337.1 29654645 1209254 1297839..1298006 1 NC_002971.3 hypothetical protein 1298006 1209254 CBU_1348 Coxiella burnetii RSA 493 hypothetical protein NP_820337.1 1297839 D 227377 CDS NP_820338.2 215919168 1209255 1298083..1299822 1 NC_002971.3 hypothetical protein 1299822 1209255 CBU_1349 Coxiella burnetii RSA 493 hypothetical protein NP_820338.2 1298083 D 227377 CDS NP_820339.1 29654647 1209256 complement(1299935..1301275) 1 NC_002971.3 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1301275 glmM 1209256 glmM Coxiella burnetii RSA 493 phosphoglucosamine mutase NP_820339.1 1299935 R 227377 CDS NP_820340.1 29654648 1209257 complement(1301364..1302257) 1 NC_002971.3 dihydropteroate synthase 1302257 folP 1209257 folP Coxiella burnetii RSA 493 dihydropteroate synthase NP_820340.1 1301364 R 227377 CDS NP_820341.1 29654649 1209258 complement(1302309..1304252) 1 NC_002971.3 ATP-dependent metallopeptidase HflB 1304252 ftsH 1209258 ftsH Coxiella burnetii RSA 493 ATP-dependent metallopeptidase HflB NP_820341.1 1302309 R 227377 CDS NP_820342.1 29654650 1209259 complement(1304272..1304910) 1 NC_002971.3 23S rRNA Um2552 2'-O-methyltransferase 1304910 rrmJ 1209259 rrmJ Coxiella burnetii RSA 493 23S rRNA Um2552 2'-O-methyltransferase NP_820342.1 1304272 R 227377 CDS NP_820343.1 29654651 1209260 complement(1304932..1305474) 1 NC_002971.3 hypothetical protein 1305474 1209260 CBU_1354 Coxiella burnetii RSA 493 hypothetical protein NP_820343.1 1304932 R 227377 CDS NP_820344.1 29654652 1209261 complement(1305476..1305829) 1 NC_002971.3 FeS assembly scaffold SufA 1305829 1209261 CBU_1355 Coxiella burnetii RSA 493 FeS assembly scaffold SufA NP_820344.1 1305476 R 227377 CDS NP_820345.1 29654653 1209262 complement(1305826..1306302) 1 NC_002971.3 NifU family SUF system FeS assembly protein 1306302 iscU.2 1209262 iscU.2 Coxiella burnetii RSA 493 NifU family SUF system FeS assembly protein NP_820345.1 1305826 R 227377 CDS NP_820346.1 29654654 1209263 complement(1306295..1307512) 1 NC_002971.3 cysteine desulfurase 1307512 csdB 1209263 csdB Coxiella burnetii RSA 493 cysteine desulfurase NP_820346.1 1306295 R 227377 CDS NP_820347.1 29654655 1209264 complement(1307505..1308785) 1 NC_002971.3 FeS assembly protein SufD 1308785 sufD 1209264 sufD Coxiella burnetii RSA 493 FeS assembly protein SufD NP_820347.1 1307505 R 227377 CDS NP_820348.1 29654656 1209265 complement(1308782..1309516) 1 NC_002971.3 FeS assembly ATPase SufC 1309516 sufC 1209265 sufC Coxiella burnetii RSA 493 FeS assembly ATPase SufC NP_820348.1 1308782 R 227377 CDS NP_820349.2 215919169 1209266 complement(1309540..1310994) 1 NC_002971.3 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 1310994 sufB 1209266 sufB Coxiella burnetii RSA 493 cysteine desulfurase NP_820349.2 1309540 R 227377 CDS NP_820350.1 29654658 1209267 complement(1310975..1311436) 1 NC_002971.3 FeS assembly SUF system regulator 1311436 1209267 CBU_1361 Coxiella burnetii RSA 493 FeS assembly SUF system regulator NP_820350.1 1310975 R 227377 CDS NP_820351.1 29654659 1209268 1311644..1312780 1 NC_002971.3 cation diffusion facilitator family transporter 1312780 czcD.2 1209268 czcD.2 Coxiella burnetii RSA 493 cation diffusion facilitator family transporter NP_820351.1 1311644 D 227377 CDS NP_820352.1 29654660 1209269 1312773..1314149 1 NC_002971.3 exonuclease 1314149 1209269 CBU_1363 Coxiella burnetii RSA 493 exonuclease NP_820352.1 1312773 D 227377 CDS NP_820355.1 29654663 1209272 complement(1315746..1316078) 1 NC_002971.3 hypothetical protein 1316078 1209272 CBU_1366 Coxiella burnetii RSA 493 hypothetical protein NP_820355.1 1315746 R 227377 CDS NP_820358.1 29654666 1209275 1318270..1319289 1 NC_002971.3 hypothetical protein 1319289 1209275 CBU_1369 Coxiella burnetii RSA 493 hypothetical protein NP_820358.1 1318270 D 227377 CDS NP_820359.1 29654667 1209276 complement(1319489..1320475) 1 NC_002971.3 hypothetical protein 1320475 1209276 CBU_1370 Coxiella burnetii RSA 493 hypothetical protein NP_820359.1 1319489 R 227377 CDS NP_820360.1 29654668 1209277 complement(1320668..1321348) 1 NC_002971.3 non-proteolytic protein, peptidase M22 1321348 1209277 CBU_1371 Coxiella burnetii RSA 493 non-proteolytic protein, peptidase M22 NP_820360.1 1320668 R 227377 CDS NP_820361.1 29654669 1209278 complement(1321492..1322073) 1 NC_002971.3 hypothetical protein 1322073 1209278 CBU_1372 Coxiella burnetii RSA 493 hypothetical protein NP_820361.1 1321492 R 227377 CDS NP_820362.1 29654670 1209279 1322174..1323466 1 NC_002971.3 para-aminobenzoate synthetase component I 1323466 pabB 1209279 pabB Coxiella burnetii RSA 493 para-aminobenzoate synthetase component I NP_820362.1 1322174 D 227377 CDS NP_820363.1 29654671 1209280 1323463..1323942 1 NC_002971.3 cytidine/deoxycytidylate deaminase 1323942 1209280 CBU_1374 Coxiella burnetii RSA 493 cytidine/deoxycytidylate deaminase NP_820363.1 1323463 D 227377 CDS NP_820364.1 29654672 1209281 complement(1323975..1326119) 1 NC_002971.3 RelA/SpoT family protein 1326119 relA 1209281 relA Coxiella burnetii RSA 493 RelA/SpoT family protein NP_820364.1 1323975 R 227377 CDS NP_820365.1 29654673 1209282 1326197..1327561 1 NC_002971.3 membrane endopeptidase, M50 family 1327561 1209282 CBU_1376 Coxiella burnetii RSA 493 membrane endopeptidase, M50 family NP_820365.1 1326197 D 227377 CDS NP_820367.1 29654675 1209284 1328863..1328979 1 NC_002971.3 hypothetical protein 1328979 1209284 CBU_1378 Coxiella burnetii RSA 493 hypothetical protein NP_820367.1 1328863 D 227377 CDS YP_002333001.1 215919171 7065944 1330216..1331064 1 NC_002971.3 hypothetical protein 1331064 7065944 CBU_1379a Coxiella burnetii RSA 493 hypothetical protein YP_002333001.1 1330216 D 227377 CDS NP_820369.1 29654677 1209286 complement(1331100..1331945) 1 NC_002971.3 DoxD family protein 1331945 1209286 CBU_1380 Coxiella burnetii RSA 493 DoxD family protein NP_820369.1 1331100 R 227377 CDS NP_820370.1 29654678 1209287 complement(1332123..1332941) 1 NC_002971.3 phosphatidate cytidylyltransferase 1332941 cdsA 1209287 cdsA Coxiella burnetii RSA 493 phosphatidate cytidylyltransferase NP_820370.1 1332123 R 227377 CDS NP_820371.1 29654679 1209288 complement(1332931..1333644) 1 NC_002971.3 undecaprenyl pyrophosphate synthetase 1333644 uppS 1209288 uppS Coxiella burnetii RSA 493 undecaprenyl pyrophosphate synthetase NP_820371.1 1332931 R 227377 CDS NP_820372.1 29654680 1209289 complement(1333641..1334198) 1 NC_002971.3 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1334198 frr 1209289 frr Coxiella burnetii RSA 493 ribosome recycling factor NP_820372.1 1333641 R 227377 CDS NP_820373.1 29654681 1209290 complement(1334276..1335007) 1 NC_002971.3 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1335007 pyrH 1209290 pyrH Coxiella burnetii RSA 493 uridylate kinase NP_820373.1 1334276 R 227377 CDS NP_820374.1 29654682 1209291 complement(1335007..1335897) 1 NC_002971.3 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1335897 tsf 1209291 tsf Coxiella burnetii RSA 493 elongation factor Ts NP_820374.1 1335007 R 227377 CDS NP_820375.2 215919172 1209292 complement(1335907..1336986) 1 NC_002971.3 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1336986 rpsB 1209292 rpsB Coxiella burnetii RSA 493 30S ribosomal protein S2 NP_820375.2 1335907 R 227377 CDS NP_820376.1 29654684 1209293 1337068..1337718 1 NC_002971.3 hypothetical protein 1337718 1209293 CBU_1387 Coxiella burnetii RSA 493 hypothetical protein NP_820376.1 1337068 D 227377 CDS NP_820377.2 215919173 1209294 1337773..1338585 1 NC_002971.3 methionine aminopeptidase 1338585 map 1209294 map Coxiella burnetii RSA 493 methionine aminopeptidase NP_820377.2 1337773 D 227377 CDS YP_008992035.1 570699741 7065901 1341595..1342290 1 NC_002971.3 2-phosphosulfolactate phosphatase 1342290 7065901 CBU_1388d Coxiella burnetii RSA 493 2-phosphosulfolactate phosphatase YP_008992035.1 1341595 D 227377 CDS NP_820379.1 29654687 1209300 1346886..1347413 1 NC_002971.3 enhanced entry protein 1347413 enhA.5 1209300 enhA.5 Coxiella burnetii RSA 493 enhanced entry protein NP_820379.1 1346886 D 227377 CDS NP_820380.1 29654688 1209301 complement(1347432..1347878) 1 NC_002971.3 hypothetical protein 1347878 1209301 CBU_1395 Coxiella burnetii RSA 493 hypothetical protein NP_820380.1 1347432 R 227377 CDS NP_820381.1 29654689 1209302 complement(1347875..1348759) 1 NC_002971.3 succinate-CoA ligase (ADP-forming) subunit alpha 1348759 sucD 1209302 sucD Coxiella burnetii RSA 493 succinate-CoA ligase (ADP-forming) subunit alpha NP_820381.1 1347875 R 227377 CDS NP_820382.1 29654690 1209303 complement(1348759..1349931) 1 NC_002971.3 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1349931 sucC 1209303 sucC Coxiella burnetii RSA 493 succinyl-CoA synthetase subunit beta NP_820382.1 1348759 R 227377 CDS NP_820383.1 29654691 1209304 complement(1350133..1351350) 1 NC_002971.3 dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 1351350 sucB 1209304 sucB Coxiella burnetii RSA 493 dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex NP_820383.1 1350133 R 227377 CDS NP_820384.1 29654692 1209305 complement(1351360..1354164) 1 NC_002971.3 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1354164 sucA 1209305 sucA Coxiella burnetii RSA 493 2-oxoglutarate dehydrogenase E1 NP_820384.1 1351360 R 227377 CDS NP_820385.1 29654693 1209306 complement(1354188..1354919) 1 NC_002971.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1354919 sdhB 1209306 sdhB Coxiella burnetii RSA 493 succinate dehydrogenase iron-sulfur subunit NP_820385.1 1354188 R 227377 CDS NP_820386.1 29654694 1209307 complement(1354926..1356689) 1 NC_002971.3 succinate dehydrogenase flavoprotein subunit 1356689 sdhA 1209307 sdhA Coxiella burnetii RSA 493 succinate dehydrogenase flavoprotein subunit NP_820386.1 1354926 R 227377 CDS NP_820387.2 215919175 1209308 complement(1356702..1357049) 1 NC_002971.3 succinate dehydrogenase membrane anchor subunit 1357049 sdhD 1209308 sdhD Coxiella burnetii RSA 493 succinate dehydrogenase membrane anchor subunit NP_820387.2 1356702 R 227377 CDS NP_820388.2 215919176 1209309 complement(1357037..1357534) 1 NC_002971.3 succinate dehydrogenase cytochrome b556 subunit 1357534 sdhC 1209309 sdhC Coxiella burnetii RSA 493 succinate dehydrogenase cytochrome b556 subunit NP_820388.2 1357037 R 227377 CDS NP_820389.1 29654697 1209310 complement(1357547..1357879) 1 NC_002971.3 hypothetical protein 1357879 1209310 CBU_1404 Coxiella burnetii RSA 493 hypothetical protein NP_820389.1 1357547 R 227377 CDS YP_002333003.1 215919177 1209311 1357889..1358170 1 NC_002971.3 hypothetical protein 1358170 1209311 CBU_1405 Coxiella burnetii RSA 493 hypothetical protein YP_002333003.1 1357889 D 227377 CDS NP_820392.1 29654700 1209314 complement(1359188..1359292) 1 NC_002971.3 hypothetical protein 1359292 1209314 CBU_1408 Coxiella burnetii RSA 493 hypothetical protein NP_820392.1 1359188 R 227377 CDS NP_820393.2 215919178 1209315 1359670..1360506 1 NC_002971.3 hypothetical protein 1360506 1209315 CBU_1409 Coxiella burnetii RSA 493 hypothetical protein NP_820393.2 1359670 D 227377 CDS NP_820394.1 29654702 1209316 1360740..1362032 1 NC_002971.3 citrate (Si)-synthase 1362032 gltA 1209316 gltA Coxiella burnetii RSA 493 citrate (Si)-synthase NP_820394.1 1360740 D 227377 CDS NP_820395.1 29654703 1209317 1362070..1362240 1 NC_002971.3 hypothetical protein 1362240 1209317 CBU_1411 Coxiella burnetii RSA 493 hypothetical protein NP_820395.1 1362070 D 227377 CDS NP_820396.2 215919179 1209318 complement(1362284..1363105) 1 NC_002971.3 hypothetical protein 1363105 1209318 CBU_1412 Coxiella burnetii RSA 493 hypothetical protein NP_820396.2 1362284 R 227377 CDS NP_820397.1 29654705 1209319 complement(1363128..1363907) 1 NC_002971.3 hypothetical protein 1363907 1209319 CBU_1413 Coxiella burnetii RSA 493 hypothetical protein NP_820397.1 1363128 R 227377 CDS NP_820398.1 29654706 1209320 complement(1363951..1364742) 1 NC_002971.3 hypothetical protein 1364742 1209320 CBU_1414 Coxiella burnetii RSA 493 hypothetical protein NP_820398.1 1363951 R 227377 CDS NP_820399.1 29654707 1209321 complement(1364834..1365850) 1 NC_002971.3 thiamine-monophosphate kinase 1365850 thiL 1209321 thiL Coxiella burnetii RSA 493 thiamine-monophosphate kinase NP_820399.1 1364834 R 227377 CDS NP_820400.2 215919180 1209322 1365921..1366637 1 NC_002971.3 S24 family peptidase 1366637 1209322 CBU_1416 Coxiella burnetii RSA 493 S24 family peptidase NP_820400.2 1365921 D 227377 CDS NP_820401.1 29654709 1209323 complement(1366760..1367176) 1 NC_002971.3 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1367176 nusB 1209323 nusB Coxiella burnetii RSA 493 transcription antitermination protein NusB NP_820401.1 1366760 R 227377 CDS NP_820402.1 29654710 1209324 complement(1367166..1367639) 1 NC_002971.3 transcriptional regulator NrdR 1367639 nrdR 1209324 nrdR Coxiella burnetii RSA 493 transcriptional regulator NrdR NP_820402.1 1367166 R 227377 CDS NP_820403.1 29654711 1209325 complement(1367639..1368898) 1 NC_002971.3 'catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate'; serine hydroxymethyltransferase 1368898 glyA 1209325 glyA Coxiella burnetii RSA 493 serine hydroxymethyltransferase NP_820403.1 1367639 R 227377 CDS NP_820406.1 29654714 1209328 complement(1370189..1371544) 1 NC_002971.3 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1371544 radA 1209328 radA Coxiella burnetii RSA 493 DNA repair protein RadA NP_820406.1 1370189 R 227377 CDS YP_002333004.1 215919181 7065932 1371624..1371767 1 NC_002971.3 hypothetical protein 1371767 7065932 CBU_1422a Coxiella burnetii RSA 493 hypothetical protein YP_002333004.1 1371624 D 227377 CDS NP_820408.1 29654716 1209330 complement(1371917..1372921) 1 NC_002971.3 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1372921 hemB 1209330 hemB Coxiella burnetii RSA 493 delta-aminolevulinic acid dehydratase NP_820408.1 1371917 R 227377 CDS NP_820409.1 29654717 1209331 complement(1372939..1373391) 1 NC_002971.3 hypothetical protein 1373391 1209331 CBU_1425 Coxiella burnetii RSA 493 hypothetical protein NP_820409.1 1372939 R 227377 CDS NP_820410.1 29654718 1209332 1373376..1373489 1 NC_002971.3 hypothetical protein 1373489 1209332 CBU_1426 Coxiella burnetii RSA 493 hypothetical protein NP_820410.1 1373376 D 227377 CDS YP_002333005.1 215919182 7065896 complement(1379319..1379435) 1 NC_002971.3 hypothetical protein 1379435 7065896 CBU_1427a Coxiella burnetii RSA 493 hypothetical protein YP_002333005.1 1379319 R 227377 CDS NP_820413.1 29654721 1209335 1379567..1380112 1 NC_002971.3 hypothetical protein 1380112 1209335 CBU_1429 Coxiella burnetii RSA 493 hypothetical protein NP_820413.1 1379567 D 227377 CDS YP_002333006.1 215919183 7065974 1380572..1380916 1 NC_002971.3 hypothetical protein 1380916 7065974 CBU_1429a Coxiella burnetii RSA 493 hypothetical protein YP_002333006.1 1380572 D 227377 CDS YP_338283.1 77358714 1209336 complement(1380921..1381850) 1 NC_002971.3 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1381850 truB 1209336 truB Coxiella burnetii RSA 493 tRNA pseudouridine synthase B YP_338283.1 1380921 R 227377 CDS NP_820414.1 29654722 1209337 complement(1381828..1382187) 1 NC_002971.3 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1382187 rbfA 1209337 rbfA Coxiella burnetii RSA 493 ribosome-binding factor A NP_820414.1 1381828 R 227377 CDS NP_820415.1 29654723 1209338 complement(1382275..1384686) 1 NC_002971.3 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1384686 infB 1209338 infB Coxiella burnetii RSA 493 translation initiation factor IF-2 NP_820415.1 1382275 R 227377 CDS NP_820416.1 29654724 1209339 complement(1384692..1386203) 1 NC_002971.3 'modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination'; transcription elongation factor NusA 1386203 nusA 1209339 nusA Coxiella burnetii RSA 493 transcription elongation factor NusA NP_820416.1 1384692 R 227377 CDS NP_820417.1 29654725 1209340 complement(1386207..1386668) 1 NC_002971.3 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1386668 1209340 CBU_1434 Coxiella burnetii RSA 493 hypothetical protein NP_820417.1 1386207 R 227377 CDS NP_820418.1 29654726 1209342 complement(1387046..1388494) 1 NC_002971.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1388494 nuoN 1209342 nuoN Coxiella burnetii RSA 493 NADH dehydrogenase subunit N NP_820418.1 1387046 R 227377 CDS NP_820419.1 29654727 1209343 complement(1388504..1390024) 1 NC_002971.3 NADH dehydrogenase subunit M 1390024 nuoM 1209343 nuoM Coxiella burnetii RSA 493 NADH dehydrogenase subunit M NP_820419.1 1388504 R 227377 CDS NP_820420.1 29654728 1209344 complement(1390029..1391990) 1 NC_002971.3 NADH dehydrogenase subunit L 1391990 nuoL 1209344 nuoL Coxiella burnetii RSA 493 NADH dehydrogenase subunit L NP_820420.1 1390029 R 227377 CDS NP_820421.1 29654729 1209345 complement(1392047..1392352) 1 NC_002971.3 NADH dehydrogenase subunit K 1392352 nuoK 1209345 nuoK Coxiella burnetii RSA 493 NADH dehydrogenase subunit K NP_820421.1 1392047 R 227377 CDS NP_820422.1 29654730 1209346 complement(1392349..1392954) 1 NC_002971.3 NADH dehydrogenase subunit J 1392954 nuoJ 1209346 nuoJ Coxiella burnetii RSA 493 NADH dehydrogenase subunit J NP_820422.1 1392349 R 227377 CDS NP_820423.2 215919184 1209347 complement(1392968..1393474) 1 NC_002971.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1393474 nuoI 1209347 nuoI Coxiella burnetii RSA 493 NADH dehydrogenase subunit I NP_820423.2 1392968 R 227377 CDS NP_820424.1 29654732 1209348 complement(1393456..1394478) 1 NC_002971.3 NADH dehydrogenase subunit H 1394478 nuoH 1209348 nuoH Coxiella burnetii RSA 493 NADH dehydrogenase subunit H NP_820424.1 1393456 R 227377 CDS NP_820425.1 29654733 1209349 complement(1394478..1396841) 1 NC_002971.3 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1396841 nuoG 1209349 nuoG Coxiella burnetii RSA 493 NADH dehydrogenase subunit G NP_820425.1 1394478 R 227377 CDS NP_820426.1 29654734 1209350 complement(1396952..1398220) 1 NC_002971.3 NADH dehydrogenase subunit F 1398220 nuoF 1209350 nuoF Coxiella burnetii RSA 493 NADH dehydrogenase subunit F NP_820426.1 1396952 R 227377 CDS NP_820427.1 29654735 1209351 complement(1398210..1398734) 1 NC_002971.3 NADH dehydrogenase subunit E 1398734 nuoE 1209351 nuoE Coxiella burnetii RSA 493 NADH dehydrogenase subunit E NP_820427.1 1398210 R 227377 CDS NP_820428.1 29654736 1209352 complement(1398734..1399987) 1 NC_002971.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1399987 nuoD 1209352 nuoD Coxiella burnetii RSA 493 NADH dehydrogenase subunit D NP_820428.1 1398734 R 227377 CDS NP_820429.1 29654737 1209353 complement(1399980..1400663) 1 NC_002971.3 NADH dehydrogenase subunit C 1400663 nuoC 1209353 nuoC Coxiella burnetii RSA 493 NADH dehydrogenase subunit C NP_820429.1 1399980 R 227377 CDS NP_820430.1 29654738 1209354 complement(1400673..1401158) 1 NC_002971.3 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1401158 nuoB 1209354 nuoB Coxiella burnetii RSA 493 NADH dehydrogenase subunit B NP_820430.1 1400673 R 227377 CDS NP_820431.2 215919185 1209355 complement(1401163..1401525) 1 NC_002971.3 NADH dehydrogenase subunit A 1401525 nuoA 1209355 nuoA Coxiella burnetii RSA 493 NADH dehydrogenase subunit A NP_820431.2 1401163 R 227377 CDS NP_820432.1 29654740 1209357 complement(1401816..1402112) 1 NC_002971.3 protein translocase subunit 1402112 secG 1209357 secG Coxiella burnetii RSA 493 protein translocase subunit NP_820432.1 1401816 R 227377 CDS NP_820433.2 215919186 1209358 complement(1402094..1402909) 1 NC_002971.3 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1402909 tpiA 1209358 tpiA Coxiella burnetii RSA 493 triosephosphate isomerase NP_820433.2 1402094 R 227377 CDS NP_820434.1 29654742 1209359 complement(1403714..1405282) 1 NC_002971.3 hypothetical protein 1405282 1209359 CBU_1451 Coxiella burnetii RSA 493 hypothetical protein NP_820434.1 1403714 R 227377 CDS NP_820440.1 29654748 1209365 complement(1409997..1412027) 1 NC_002971.3 hypothetical protein 1412027 1209365 CBU_1457 Coxiella burnetii RSA 493 hypothetical protein NP_820440.1 1409997 R 227377 CDS NP_820441.1 29654749 1209366 1412209..1413369 1 NC_002971.3 ATPase 1413369 1209366 CBU_1458 Coxiella burnetii RSA 493 ATPase NP_820441.1 1412209 D 227377 CDS YP_002333007.1 215919187 7065979 complement(1413492..1413638) 1 NC_002971.3 hypothetical protein 1413638 7065979 CBU_1458a Coxiella burnetii RSA 493 hypothetical protein YP_002333007.1 1413492 R 227377 CDS NP_820442.1 29654750 1209367 1413736..1414116 1 NC_002971.3 hypothetical protein 1414116 1209367 CBU_1459 Coxiella burnetii RSA 493 hypothetical protein NP_820442.1 1413736 D 227377 CDS NP_820443.1 29654751 1209368 complement(1414164..1414949) 1 NC_002971.3 hypothetical protein 1414949 1209368 CBU_1460 Coxiella burnetii RSA 493 hypothetical protein NP_820443.1 1414164 R 227377 CDS YP_002333008.1 215919188 7065887 complement(1417770..1417934) 1 NC_002971.3 hypothetical protein 1417934 7065887 CBU_1462a Coxiella burnetii RSA 493 hypothetical protein YP_002333008.1 1417770 R 227377 CDS NP_820446.1 29654754 1209373 complement(1418295..1418492) 1 NC_002971.3 hypothetical protein 1418492 1209373 CBU_1463 Coxiella burnetii RSA 493 hypothetical protein NP_820446.1 1418295 R 227377 CDS NP_820447.1 29654755 1209374 complement(1418495..1418779) 1 NC_002971.3 DNA-binding protein HU 1418779 hupB 1209374 hupB Coxiella burnetii RSA 493 DNA-binding protein HU NP_820447.1 1418495 R 227377 CDS NP_820448.1 29654756 1209375 1419084..1419542 1 NC_002971.3 hypothetical protein 1419542 1209375 CBU_1465 Coxiella burnetii RSA 493 hypothetical protein NP_820448.1 1419084 D 227377 CDS NP_820449.1 29654757 1209376 1419547..1419888 1 NC_002971.3 hypothetical protein 1419888 1209376 CBU_1466 Coxiella burnetii RSA 493 hypothetical protein NP_820449.1 1419547 D 227377 CDS NP_820450.1 29654758 1209377 complement(1419865..1421298) 1 NC_002971.3 protease TldD 1421298 tldD 1209377 tldD Coxiella burnetii RSA 493 protease TldD NP_820450.1 1419865 R 227377 CDS NP_820451.2 215919189 1209378 complement(1421369..1424830) 1 NC_002971.3 hypothetical protein 1424830 1209378 CBU_1468 Coxiella burnetii RSA 493 hypothetical protein NP_820451.2 1421369 R 227377 CDS NP_820452.1 29654760 1209379 complement(1424830..1425318) 1 NC_002971.3 rod shape-determining protein 1425318 mreD 1209379 mreD Coxiella burnetii RSA 493 rod shape-determining protein NP_820452.1 1424830 R 227377 CDS NP_820453.1 29654761 1209380 complement(1425324..1426202) 1 NC_002971.3 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1426202 mreC 1209380 mreC Coxiella burnetii RSA 493 rod shape-determining protein MreC NP_820453.1 1425324 R 227377 CDS NP_820454.1 29654762 1209381 complement(1426285..1427343) 1 NC_002971.3 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1427343 mreB 1209381 mreB Coxiella burnetii RSA 493 rod shape-determining protein MreB NP_820454.1 1426285 R 227377 CDS NP_820455.1 29654763 1209382 1427545..1427745 1 NC_002971.3 hypothetical protein 1427745 1209382 CBU_1472 Coxiella burnetii RSA 493 hypothetical protein NP_820455.1 1427545 D 227377 CDS NP_820456.1 29654764 1209383 1427893..1428192 1 NC_002971.3 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase subunit C 1428192 gatC 1209383 gatC Coxiella burnetii RSA 493 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase subunit C NP_820456.1 1427893 D 227377 CDS NP_820457.1 29654765 1209384 1428196..1429647 1 NC_002971.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1429647 gatA 1209384 gatA Coxiella burnetii RSA 493 aspartyl/glutamyl-tRNA amidotransferase subunit A NP_820457.1 1428196 D 227377 CDS NP_820458.1 29654766 1209385 1429652..1431085 1 NC_002971.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1431085 gatB 1209385 gatB Coxiella burnetii RSA 493 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_820458.1 1429652 D 227377 CDS NP_820459.1 29654767 1209386 complement(1431229..1432164) 1 NC_002971.3 hydrogen peroxide-inducible genes activator 1432164 oxyR 1209386 oxyR Coxiella burnetii RSA 493 hydrogen peroxide-inducible genes activator NP_820459.1 1431229 R 227377 CDS NP_820460.1 29654768 1209387 1432292..1432831 1 NC_002971.3 anti-oxidant AhpCTSA family protein 1432831 1209387 CBU_1477 Coxiella burnetii RSA 493 anti-oxidant AhpCTSA family protein NP_820460.1 1432292 D 227377 CDS NP_820461.2 215919190 1209388 1432850..1433467 1 NC_002971.3 alkylhydroperoxidase 1433467 ahpD 1209388 ahpD Coxiella burnetii RSA 493 alkylhydroperoxidase NP_820461.2 1432850 D 227377 CDS NP_820462.2 215919191 1209389 complement(1433496..1433888) 1 NC_002971.3 hypothetical protein 1433888 1209389 CBU_1479 Coxiella burnetii RSA 493 hypothetical protein NP_820462.2 1433496 R 227377 CDS NP_820463.1 29654771 1209390 complement(1433912..1434562) 1 NC_002971.3 hypothetical protein 1434562 1209390 CBU_1480 Coxiella burnetii RSA 493 hypothetical protein NP_820463.1 1433912 R 227377 CDS NP_820464.1 29654772 1209391 complement(1434559..1434912) 1 NC_002971.3 hypothetical protein 1434912 1209391 CBU_1481 Coxiella burnetii RSA 493 hypothetical protein NP_820464.1 1434559 R 227377 CDS NP_820465.1 29654773 1209392 complement(1435133..1435882) 1 NC_002971.3 hypothetical protein 1435882 1209392 CBU_1482 Coxiella burnetii RSA 493 hypothetical protein NP_820465.1 1435133 R 227377 CDS NP_820466.1 29654774 1209393 complement(1435882..1437258) 1 NC_002971.3 nfeD family protein 1437258 1209393 CBU_1483 Coxiella burnetii RSA 493 nfeD family protein NP_820466.1 1435882 R 227377 CDS NP_820467.1 29654775 1209394 1437348..1438634 1 NC_002971.3 MFS superfamily transporter 1438634 1209394 CBU_1484 Coxiella burnetii RSA 493 MFS superfamily transporter NP_820467.1 1437348 D 227377 CDS NP_820468.2 215919192 1209395 complement(1438631..1439308) 1 NC_002971.3 cyclin 1439308 1209395 CBU_1485 Coxiella burnetii RSA 493 cyclin NP_820468.2 1438631 R 227377 CDS NP_820469.1 29654777 1209396 1439405..1439572 1 NC_002971.3 hypothetical protein 1439572 1209396 CBU_1486 Coxiella burnetii RSA 493 hypothetical protein NP_820469.1 1439405 D 227377 CDS NP_820470.2 215919193 1209397 complement(1439626..1441008) 1 NC_002971.3 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1441008 cysS 1209397 cysS Coxiella burnetii RSA 493 cysteinyl-tRNA synthetase NP_820470.2 1439626 R 227377 CDS NP_820471.2 215919194 1209398 complement(1440999..1442396) 1 NC_002971.3 glutamyl-tRNA synthetase 1442396 gltX-2 1209398 gltX-2 Coxiella burnetii RSA 493 glutamyl-tRNA synthetase NP_820471.2 1440999 R 227377 CDS NP_820472.1 29654780 1209399 1442553..1443284 1 NC_002971.3 'catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine'; UDP-2,3-diacylglucosamine hydrolase 1443284 lpxH 1209399 lpxH Coxiella burnetii RSA 493 UDP-2,3-diacylglucosamine hydrolase NP_820472.1 1442553 D 227377 CDS NP_820473.2 215919195 1209400 complement(1443353..1443664) 1 NC_002971.3 addiction module antidote protein 1443664 higA 1209400 higA Coxiella burnetii RSA 493 addiction module antidote protein NP_820473.2 1443353 R 227377 CDS NP_820474.2 215919196 1209401 complement(1443670..1444008) 1 NC_002971.3 plasmid maintenance system killer protein 1444008 1209401 CBU_1491 Coxiella burnetii RSA 493 plasmid maintenance system killer protein NP_820474.2 1443670 R 227377 CDS NP_820475.1 29654783 1209402 1444367..1445512 1 NC_002971.3 ISAs1 family transposase 1445512 1209402 CBU_1492 Coxiella burnetii RSA 493 ISAs1 family transposase NP_820475.1 1444367 D 227377 CDS NP_820476.2 215919197 1209403 1445840..1447513 1 NC_002971.3 hypothetical protein 1447513 1209403 CBU_1493 Coxiella burnetii RSA 493 hypothetical protein NP_820476.2 1445840 D 227377 CDS NP_820477.2 215919198 1209404 complement(1447687..1448442) 1 NC_002971.3 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1448442 pdxJ 1209404 pdxJ Coxiella burnetii RSA 493 pyridoxine 5'-phosphate synthase NP_820477.2 1447687 R 227377 CDS NP_820480.1 29654788 1209407 complement(1450854..1450985) 1 NC_002971.3 hypothetical protein 1450985 1209407 CBU_1497 Coxiella burnetii RSA 493 hypothetical protein NP_820480.1 1450854 R 227377 CDS NP_820484.1 29654792 1209411 complement(1452327..1453022) 1 NC_002971.3 DNA repair protein 1453022 recO 1209411 recO Coxiella burnetii RSA 493 DNA repair protein NP_820484.1 1452327 R 227377 CDS NP_820485.1 29654793 1209412 complement(1453019..1453906) 1 NC_002971.3 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1453906 era 1209412 era Coxiella burnetii RSA 493 GTP-binding protein Era NP_820485.1 1453019 R 227377 CDS NP_820486.1 29654794 1209413 complement(1453903..1454604) 1 NC_002971.3 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1454604 rnc 1209413 rnc Coxiella burnetii RSA 493 ribonuclease III NP_820486.1 1453903 R 227377 CDS NP_820487.1 29654795 1209414 complement(1454625..1455395) 1 NC_002971.3 signal peptidase I 1455395 lepB-2 1209414 lepB-2 Coxiella burnetii RSA 493 signal peptidase I NP_820487.1 1454625 R 227377 CDS NP_820488.1 29654796 1209415 complement(1455392..1457236) 1 NC_002971.3 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1457236 lepA 1209415 lepA Coxiella burnetii RSA 493 GTP-binding protein LepA NP_820488.1 1455392 R 227377 CDS NP_820489.1 29654797 1209416 complement(1457372..1457809) 1 NC_002971.3 thioesterase 1457809 1209416 CBU_1506 Coxiella burnetii RSA 493 thioesterase NP_820489.1 1457372 R 227377 CDS NP_820490.1 29654798 1209417 complement(1457826..1460054) 1 NC_002971.3 copper-exporting ATPase 1460054 1209417 CBU_1507 Coxiella burnetii RSA 493 copper-exporting ATPase NP_820490.1 1457826 R 227377 CDS NP_820491.1 29654799 1209418 complement(1460077..1461708) 1 NC_002971.3 ATPase 1461708 1209418 CBU_1508 Coxiella burnetii RSA 493 ATPase NP_820491.1 1460077 R 227377 CDS NP_820492.1 29654800 1209419 complement(1461786..1463135) 1 NC_002971.3 tRNA(Ile)-lysidine synthase 1463135 tilS 1209419 tilS Coxiella burnetii RSA 493 tRNA(Ile)-lysidine synthase NP_820492.1 1461786 R 227377 CDS NP_820493.1 29654801 1209420 complement(1463111..1464061) 1 NC_002971.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1464061 accA 1209420 accA Coxiella burnetii RSA 493 acetyl-CoA carboxylase carboxyltransferase subunit alpha NP_820493.1 1463111 R 227377 CDS NP_820494.1 29654802 1209421 1464210..1464995 1 NC_002971.3 ZIP family protein 1464995 1209421 CBU_1511 Coxiella burnetii RSA 493 ZIP family protein NP_820494.1 1464210 D 227377 CDS NP_820495.1 29654803 1209422 complement(1464992..1465705) 1 NC_002971.3 rhodanese domain-containing protein 1465705 1209422 CBU_1512 Coxiella burnetii RSA 493 rhodanese domain-containing protein NP_820495.1 1464992 R 227377 CDS NP_820496.1 29654804 1209423 complement(1465709..1466485) 1 NC_002971.3 short chain dehydrogenase/reductase oxidoreductase 1466485 1209423 CBU_1513 Coxiella burnetii RSA 493 short chain dehydrogenase/reductase oxidoreductase NP_820496.1 1465709 R 227377 CDS NP_820497.3 570699732 1209424 1466604..1467296 1 NC_002971.3 short-chain dehydrogenase 1467296 1209424 CBU_1514 Coxiella burnetii RSA 493 short-chain dehydrogenase NP_820497.3 1466604 D 227377 CDS NP_820498.1 29654806 1209425 1467300..1467518 1 NC_002971.3 hypothetical protein 1467518 1209425 CBU_1515 Coxiella burnetii RSA 493 hypothetical protein NP_820498.1 1467300 D 227377 CDS NP_820500.1 29654808 1209427 1468222..1468680 1 NC_002971.3 RNA methyltransferase 1468680 1209427 CBU_1517 Coxiella burnetii RSA 493 RNA methyltransferase NP_820500.1 1468222 D 227377 CDS NP_820501.1 29654809 1209428 complement(1468708..1469706) 1 NC_002971.3 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1469706 gpsA 1209428 gpsA Coxiella burnetii RSA 493 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_820501.1 1468708 R 227377 CDS NP_820502.1 29654810 1209429 complement(1469775..1470260) 1 NC_002971.3 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1470260 secB 1209429 secB Coxiella burnetii RSA 493 preprotein translocase subunit SecB NP_820502.1 1469775 R 227377 CDS NP_820503.1 29654811 1209430 complement(1470273..1470530) 1 NC_002971.3 glutaredoxin 1470530 grxC 1209430 grxC Coxiella burnetii RSA 493 glutaredoxin NP_820503.1 1470273 R 227377 CDS NP_820504.1 29654812 1209431 complement(1470535..1470969) 1 NC_002971.3 rhodanese domain-containing protein 1470969 1209431 CBU_1521 Coxiella burnetii RSA 493 rhodanese domain-containing protein NP_820504.1 1470535 R 227377 CDS NP_820505.1 29654813 1209432 complement(1471019..1471144) 1 NC_002971.3 hypothetical protein 1471144 1209432 CBU_1522 Coxiella burnetii RSA 493 hypothetical protein NP_820505.1 1471019 R 227377 CDS YP_002333009.1 215919200 7065948 complement(1475486..1475581) 1 NC_002971.3 hypothetical protein 1475581 7065948 CBU_1526a Coxiella burnetii RSA 493 hypothetical protein YP_002333009.1 1475486 R 227377 CDS NP_820512.1 29654820 1209439 complement(1477207..1479117) 1 NC_002971.3 peptidase catalytic domain protein of S9A/B/C families 1479117 1209439 CBU_1529 Coxiella burnetii RSA 493 peptidase catalytic domain protein of S9A/B/C families NP_820512.1 1477207 R 227377 CDS NP_820513.1 29654821 1209440 complement(1479184..1481121) 1 NC_002971.3 hypothetical protein 1481121 1209440 CBU_1530 Coxiella burnetii RSA 493 hypothetical protein NP_820513.1 1479184 R 227377 CDS YP_002333010.1 215919201 7065865 complement(1481160..1481459) 1 NC_002971.3 hypothetical protein 1481459 7065865 CBU_1530a Coxiella burnetii RSA 493 hypothetical protein YP_002333010.1 1481160 R 227377 CDS NP_820519.1 29654827 1209446 1484958..1486517 1 NC_002971.3 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1486517 yibO 1209446 yibO Coxiella burnetii RSA 493 phosphoglyceromutase NP_820519.1 1484958 D 227377 CDS NP_820520.2 215919202 1209447 1486521..1487762 1 NC_002971.3 peptidase M23/M37 domain-containing protein 1487762 1209447 CBU_1537 Coxiella burnetii RSA 493 peptidase M23/M37 domain-containing protein NP_820520.2 1486521 D 227377 CDS NP_820521.1 29654829 1209448 1487759..1489129 1 NC_002971.3 peptidase 1489129 1209448 CBU_1538 Coxiella burnetii RSA 493 peptidase NP_820521.1 1487759 D 227377 CDS NP_820522.1 29654830 1209449 1489153..1490433 1 NC_002971.3 tyrosine-specific transport protein 1490433 1209449 CBU_1539 Coxiella burnetii RSA 493 tyrosine-specific transport protein NP_820522.1 1489153 D 227377 CDS NP_820523.1 29654831 1209450 1490460..1490789 1 NC_002971.3 hypothetical protein 1490789 1209450 CBU_1540 Coxiella burnetii RSA 493 hypothetical protein NP_820523.1 1490460 D 227377 CDS NP_820524.1 29654832 1209451 1490823..1490921 1 NC_002971.3 hypothetical protein 1490921 1209451 CBU_1541 Coxiella burnetii RSA 493 hypothetical protein NP_820524.1 1490823 D 227377 CDS NP_820525.1 29654833 1209452 complement(1490956..1491285) 1 NC_002971.3 hypothetical protein 1491285 1209452 CBU_1542 Coxiella burnetii RSA 493 hypothetical protein NP_820525.1 1490956 R 227377 CDS NP_820526.1 29654834 1209453 complement(1491599..1492165) 1 NC_002971.3 hypothetical protein 1492165 1209453 CBU_1543 Coxiella burnetii RSA 493 hypothetical protein NP_820526.1 1491599 R 227377 CDS NP_820527.1 29654835 1209454 complement(1492282..1493274) 1 NC_002971.3 IS30 family transposase 1493274 1209454 CBU_1544 Coxiella burnetii RSA 493 IS30 family transposase NP_820527.1 1492282 R 227377 CDS NP_820530.1 29654838 1209457 complement(1494313..1495107) 1 NC_002971.3 'ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived'; thymidylate synthase 1495107 thyA 1209457 thyA Coxiella burnetii RSA 493 thymidylate synthase NP_820530.1 1494313 R 227377 CDS NP_820531.1 29654839 1209458 complement(1495104..1495478) 1 NC_002971.3 hypothetical protein 1495478 1209458 CBU_1548 Coxiella burnetii RSA 493 hypothetical protein NP_820531.1 1495104 R 227377 CDS NP_820532.1 29654840 1209459 complement(1495480..1496265) 1 NC_002971.3 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1496265 lgt 1209459 lgt Coxiella burnetii RSA 493 prolipoprotein diacylglyceryl transferase NP_820532.1 1495480 R 227377 CDS NP_820533.2 215919203 1209460 complement(1496320..1498620) 1 NC_002971.3 phosphoenolpyruvate-protein phosphotransferase 1498620 ptsP 1209460 ptsP Coxiella burnetii RSA 493 phosphoenolpyruvate-protein phosphotransferase NP_820533.2 1496320 R 227377 CDS NP_820534.1 29654842 1209461 complement(1498601..1499287) 1 NC_002971.3 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1499287 1209461 CBU_1551 Coxiella burnetii RSA 493 dinucleoside polyphosphate hydrolase NP_820534.1 1498601 R 227377 CDS NP_820535.1 29654843 1209462 complement(1499341..1499451) 1 NC_002971.3 hypothetical protein 1499451 1209462 CBU_1552 Coxiella burnetii RSA 493 hypothetical protein NP_820535.1 1499341 R 227377 CDS YP_002333011.1 215919204 7065958 1499504..1499605 1 NC_002971.3 hypothetical protein 1499605 7065958 CBU_1552a Coxiella burnetii RSA 493 hypothetical protein YP_002333011.1 1499504 D 227377 CDS NP_820536.1 29654844 1209463 1499627..1502452 1 NC_002971.3 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1502452 nrdA 1209463 nrdA Coxiella burnetii RSA 493 ribonucleotide-diphosphate reductase subunit alpha NP_820536.1 1499627 D 227377 CDS NP_820537.1 29654845 1209464 1502502..1503707 1 NC_002971.3 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit beta 1503707 nrdB 1209464 nrdB Coxiella burnetii RSA 493 ribonucleotide-diphosphate reductase subunit beta NP_820537.1 1502502 D 227377 CDS NP_820538.1 29654846 1209465 1504001..1505146 1 NC_002971.3 ISAs1 family transposase 1505146 1209465 CBU_1555 Coxiella burnetii RSA 493 ISAs1 family transposase NP_820538.1 1504001 D 227377 CDS NP_820539.1 29654847 1209466 1505256..1506959 1 NC_002971.3 hypothetical protein 1506959 1209466 CBU_1556 Coxiella burnetii RSA 493 hypothetical protein NP_820539.1 1505256 D 227377 CDS NP_820541.1 29654849 1209468 1507346..1507621 1 NC_002971.3 FmdB transcriptional regulator family 1507621 1209468 CBU_1558 Coxiella burnetii RSA 493 FmdB transcriptional regulator family NP_820541.1 1507346 D 227377 CDS NP_820542.1 29654850 1209469 1507618..1508247 1 NC_002971.3 hypothetical protein 1508247 1209469 CBU_1559 Coxiella burnetii RSA 493 hypothetical protein NP_820542.1 1507618 D 227377 CDS YP_002333012.1 215919205 7065898 1508416..1508508 1 NC_002971.3 hypothetical protein 1508508 7065898 CBU_1559a Coxiella burnetii RSA 493 hypothetical protein YP_002333012.1 1508416 D 227377 CDS NP_820543.1 29654851 1209470 1508557..1508682 1 NC_002971.3 hypothetical protein 1508682 1209470 CBU_1560 Coxiella burnetii RSA 493 hypothetical protein NP_820543.1 1508557 D 227377 CDS NP_820544.2 215919206 1209471 1508765..1509553 1 NC_002971.3 hypothetical protein 1509553 1209471 CBU_1561 Coxiella burnetii RSA 493 hypothetical protein NP_820544.2 1508765 D 227377 CDS NP_820548.2 215919207 1209475 1512191..1514023 1 NC_002971.3 'catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes'; aspartyl-tRNA synthetase 1514023 aspS 1209475 aspS Coxiella burnetii RSA 493 aspartyl-tRNA synthetase NP_820548.2 1512191 D 227377 CDS NP_820549.1 29654857 1209476 1514039..1514773 1 NC_002971.3 hypothetical protein 1514773 1209476 CBU_1566 Coxiella burnetii RSA 493 hypothetical protein NP_820549.1 1514039 D 227377 CDS NP_820550.1 29654858 1209477 1514888..1515406 1 NC_002971.3 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1515406 ruvC 1209477 ruvC Coxiella burnetii RSA 493 Holliday junction resolvase NP_820550.1 1514888 D 227377 CDS NP_820551.1 29654859 1209478 1515403..1516005 1 NC_002971.3 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1516005 ruvA 1209478 ruvA Coxiella burnetii RSA 493 Holliday junction DNA helicase RuvA NP_820551.1 1515403 D 227377 CDS NP_820552.1 29654860 1209479 1516105..1517748 1 NC_002971.3 hypothetical protein 1517748 1209479 CBU_1569 Coxiella burnetii RSA 493 hypothetical protein NP_820552.1 1516105 D 227377 CDS NP_820553.1 29654861 1209480 1517858..1518913 1 NC_002971.3 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1518913 ruvB 1209480 ruvB Coxiella burnetii RSA 493 Holliday junction DNA helicase RuvB NP_820553.1 1517858 D 227377 CDS YP_002333013.1 215919208 7065978 1518999..1519271 1 NC_002971.3 hypothetical protein 1519271 7065978 CBU_1570a Coxiella burnetii RSA 493 hypothetical protein YP_002333013.1 1518999 D 227377 CDS YP_002333014.1 215919209 1209481 complement(1519268..1520362) 1 NC_002971.3 transposase 1520362 1209481 CBU_1570b Coxiella burnetii RSA 493 transposase YP_002333014.1 1519268 R 227377 CDS NP_820556.1 29654864 1209483 1520477..1521712 1 NC_002971.3 MFS superfamily transporter 1521712 1209483 CBU_1573 Coxiella burnetii RSA 493 MFS superfamily transporter NP_820556.1 1520477 D 227377 CDS NP_820557.1 29654865 1209484 1521788..1522501 1 NC_002971.3 TolQ 1522501 tolQ 1209484 tolQ Coxiella burnetii RSA 493 TolQ NP_820557.1 1521788 D 227377 CDS NP_820558.1 29654866 1209485 1522479..1522922 1 NC_002971.3 protein TolR 1522922 tolR 1209485 tolR Coxiella burnetii RSA 493 protein TolR NP_820558.1 1522479 D 227377 CDS NP_820559.1 29654867 1209486 1523065..1525584 1 NC_002971.3 hypothetical protein 1525584 1209486 CBU_1576 Coxiella burnetii RSA 493 hypothetical protein NP_820559.1 1523065 D 227377 CDS NP_820560.1 29654868 1209487 complement(1525550..1526494) 1 NC_002971.3 LysM domain-containing protein 1526494 1209487 CBU_1577 Coxiella burnetii RSA 493 LysM domain-containing protein NP_820560.1 1525550 R 227377 CDS NP_820561.1 29654869 1209488 complement(1526497..1527333) 1 NC_002971.3 hypothetical protein 1527333 1209488 CBU_1578 Coxiella burnetii RSA 493 hypothetical protein NP_820561.1 1526497 R 227377 CDS NP_820562.1 29654870 1209489 1527444..1528037 1 NC_002971.3 NAD(P)H:quinone oxidoreductase, type IV 1528037 1209489 CBU_1579 Coxiella burnetii RSA 493 NAD(P)H:quinone oxidoreductase, type IV NP_820562.1 1527444 D 227377 CDS NP_820563.1 29654871 1209490 1528034..1529131 1 NC_002971.3 ATPase 1529131 1209490 CBU_1580 Coxiella burnetii RSA 493 ATPase NP_820563.1 1528034 D 227377 CDS NP_820564.1 29654872 1209491 1529542..1529664 1 NC_002971.3 hypothetical protein 1529664 1209491 CBU_1581 Coxiella burnetii RSA 493 hypothetical protein NP_820564.1 1529542 D 227377 CDS NP_820565.1 29654873 1209492 complement(1529705..1530085) 1 NC_002971.3 Na(+)/H(+) antiporter subunit G 1530085 shaG 1209492 shaG Coxiella burnetii RSA 493 Na(+)/H(+) antiporter subunit G NP_820565.1 1529705 R 227377 CDS NP_820566.1 29654874 1209493 complement(1530078..1530380) 1 NC_002971.3 Na(+)/H(+) antiporter subunit F 1530380 shaF 1209493 shaF Coxiella burnetii RSA 493 Na(+)/H(+) antiporter subunit F NP_820566.1 1530078 R 227377 CDS NP_820567.1 29654875 1209494 complement(1530377..1530724) 1 NC_002971.3 Na(+)/H(+) antiporter subunit E 1530724 shaE 1209494 shaE Coxiella burnetii RSA 493 Na(+)/H(+) antiporter subunit E NP_820567.1 1530377 R 227377 CDS NP_820568.1 29654876 1209495 complement(1530721..1532220) 1 NC_002971.3 Na(+)/H(+) antiporter subunit D 1532220 shaD 1209495 shaD Coxiella burnetii RSA 493 Na(+)/H(+) antiporter subunit D NP_820568.1 1530721 R 227377 CDS NP_820569.1 29654877 1209496 complement(1532217..1532588) 1 NC_002971.3 Na(+)/H(+) antiporter subunit C 1532588 1209496 CBU_1586 Coxiella burnetii RSA 493 Na(+)/H(+) antiporter subunit C NP_820569.1 1532217 R 227377 CDS NP_820570.1 29654878 1209497 complement(1532585..1532992) 1 NC_002971.3 'subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali'; monovalent cation/H+ antiporter subunit B 1532992 shaB 1209497 shaB Coxiella burnetii RSA 493 monovalent cation/H+ antiporter subunit B NP_820570.1 1532585 R 227377 CDS NP_820571.1 29654879 1209498 complement(1532989..1535295) 1 NC_002971.3 'subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+'; monovalent cation/H+ antiporter subunit A 1535295 shaA 1209498 shaA Coxiella burnetii RSA 493 monovalent cation/H+ antiporter subunit A NP_820571.1 1532989 R 227377 CDS NP_820572.1 29654880 1209499 complement(1535416..1535724) 1 NC_002971.3 hypothetical protein 1535724 1209499 CBU_1589 Coxiella burnetii RSA 493 hypothetical protein NP_820572.1 1535416 R 227377 CDS NP_820573.1 29654881 1209500 1535813..1537066 1 NC_002971.3 Na(+)/H(+) antiporter NhaP 1537066 nhaP.2 1209500 nhaP.2 Coxiella burnetii RSA 493 Na(+)/H(+) antiporter NhaP NP_820573.1 1535813 D 227377 CDS YP_002333015.1 215919210 7065965 1537194..1537466 1 NC_002971.3 hypothetical protein 1537466 7065965 CBU_1590a Coxiella burnetii RSA 493 hypothetical protein YP_002333015.1 1537194 D 227377 CDS YP_002333016.1 215919211 1209501 complement(1537463..1538557) 1 NC_002971.3 transposase 1538557 1209501 CBU_1590b Coxiella burnetii RSA 493 transposase YP_002333016.1 1537463 R 227377 CDS NP_820576.2 215919212 1209503 1538657..1538917 1 NC_002971.3 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1538917 rpsU 1209503 rpsU Coxiella burnetii RSA 493 30S ribosomal protein S21 NP_820576.2 1538657 D 227377 CDS NP_820577.1 29654885 1209504 1538945..1539394 1 NC_002971.3 GatB/Yqey domain-containing protein 1539394 1209504 CBU_1594 Coxiella burnetii RSA 493 GatB/Yqey domain-containing protein NP_820577.1 1538945 D 227377 CDS NP_820578.2 215919213 1209505 1539435..1541153 1 NC_002971.3 DNA primase 1541153 dnaG 1209505 dnaG Coxiella burnetii RSA 493 DNA primase NP_820578.2 1539435 D 227377 CDS NP_820579.1 29654887 1209506 1541273..1543369 1 NC_002971.3 RNA polymerase sigma factor 1543369 rpoD 1209506 rpoD Coxiella burnetii RSA 493 RNA polymerase sigma factor NP_820579.1 1541273 D 227377 CDS NP_820580.1 29654888 1209507 complement(1543493..1543603) 1 NC_002971.3 lipoprotein 1543603 1209507 CBU_1597 Coxiella burnetii RSA 493 lipoprotein NP_820580.1 1543493 R 227377 CDS NP_820583.1 29654891 1209511 complement(1546065..1546610) 1 NC_002971.3 opacity family porin protein 1546610 1209511 CBU_1600 Coxiella burnetii RSA 493 opacity family porin protein NP_820583.1 1546065 R 227377 CDS NP_820584.1 29654892 1209512 1546941..1547426 1 NC_002971.3 hypothetical protein 1547426 1209512 CBU_1601 Coxiella burnetii RSA 493 hypothetical protein NP_820584.1 1546941 D 227377 CDS NP_820585.1 29654893 1209513 1547423..1548328 1 NC_002971.3 ribosomal protein S6 modification protein 1548328 rimK 1209513 rimK Coxiella burnetii RSA 493 ribosomal protein S6 modification protein NP_820585.1 1547423 D 227377 CDS NP_820586.1 29654894 1209514 1548331..1549359 1 NC_002971.3 succinylglutamate desuccinylase/aspartoacylase 1549359 1209514 CBU_1603 Coxiella burnetii RSA 493 succinylglutamate desuccinylase/aspartoacylase NP_820586.1 1548331 D 227377 CDS NP_820589.1 29654897 1209518 complement(1552010..1552408) 1 NC_002971.3 hypothetical protein 1552408 1209518 CBU_1607 Coxiella burnetii RSA 493 hypothetical protein NP_820589.1 1552010 R 227377 CDS NP_820594.1 29654902 1209523 complement(1555602..1555697) 1 NC_002971.3 hypothetical protein 1555697 1209523 CBU_1612 Coxiella burnetii RSA 493 hypothetical protein NP_820594.1 1555602 R 227377 CDS NP_820595.1 29654903 1209524 complement(1555801..1555956) 1 NC_002971.3 hypothetical protein 1555956 1209524 CBU_1613 Coxiella burnetii RSA 493 hypothetical protein NP_820595.1 1555801 R 227377 CDS NP_820596.1 29654904 1209525 complement(1555989..1556408) 1 NC_002971.3 hypothetical protein 1556408 1209525 CBU_1614 Coxiella burnetii RSA 493 hypothetical protein NP_820596.1 1555989 R 227377 CDS NP_820600.1 29654908 1209529 1558036..1558389 1 NC_002971.3 hypothetical protein 1558389 1209529 CBU_1618 Coxiella burnetii RSA 493 hypothetical protein NP_820600.1 1558036 D 227377 CDS NP_820603.1 29654911 1209532 1559190..1559327 1 NC_002971.3 hypothetical protein 1559327 1209532 CBU_1621 Coxiella burnetii RSA 493 hypothetical protein NP_820603.1 1559190 D 227377 CDS NP_820604.1 29654912 1209533 complement(1559342..1562353) 1 NC_002971.3 IcmB 1562353 icmB 1209533 icmB Coxiella burnetii RSA 493 IcmB NP_820604.1 1559342 R 227377 CDS NP_820605.1 29654913 1209534 complement(1562426..1563064) 1 NC_002971.3 IcmJ 1563064 icmJ 1209534 icmJ Coxiella burnetii RSA 493 IcmJ NP_820605.1 1562426 R 227377 CDS NP_820606.1 29654914 1209535 complement(1563077..1563493) 1 NC_002971.3 hypothetical protein 1563493 icmD 1209535 icmD Coxiella burnetii RSA 493 hypothetical protein NP_820606.1 1563077 R 227377 CDS NP_820607.1 29654915 1209536 complement(1563587..1564096) 1 NC_002971.3 hypothetical protein 1564096 icmC 1209536 icmC Coxiella burnetii RSA 493 hypothetical protein NP_820607.1 1563587 R 227377 CDS NP_820608.1 29654916 1209537 complement(1564167..1564901) 1 NC_002971.3 hypothetical protein 1564901 icmG 1209537 icmG Coxiella burnetii RSA 493 hypothetical protein NP_820608.1 1564167 R 227377 CDS NP_820609.2 215919214 1209538 complement(1564919..1568038) 1 NC_002971.3 IcmE 1568038 icmE 1209538 icmE Coxiella burnetii RSA 493 IcmE NP_820609.2 1564919 R 227377 CDS NP_820610.2 215919215 1209539 complement(1568025..1569080) 1 NC_002971.3 IcmK 1569080 icmK 1209539 icmK Coxiella burnetii RSA 493 IcmK NP_820610.2 1568025 R 227377 CDS NP_820611.1 29654919 1209540 complement(1569091..1569747) 1 NC_002971.3 IcmL 1569747 icmL.1 1209540 icmL.1 Coxiella burnetii RSA 493 IcmL NP_820611.1 1569091 R 227377 CDS NP_820612.1 29654920 1209541 complement(1569749..1570372) 1 NC_002971.3 IcmL 1570372 icmL.2 1209541 icmL.2 Coxiella burnetii RSA 493 IcmL NP_820612.1 1569749 R 227377 CDS NP_820613.2 215919216 1209542 complement(1570379..1571017) 1 NC_002971.3 ompA family protein 1571017 icmN 1209542 icmN Coxiella burnetii RSA 493 ompA family protein NP_820613.2 1570379 R 227377 CDS NP_820614.1 29654922 1209543 complement(1571027..1573405) 1 NC_002971.3 IcmO 1573405 icmO 1209543 icmO Coxiella burnetii RSA 493 IcmO NP_820614.1 1571027 R 227377 CDS NP_820615.1 29654923 1209544 complement(1573381..1574544) 1 NC_002971.3 IcmP 1574544 icmP 1209544 icmP Coxiella burnetii RSA 493 IcmP NP_820615.1 1573381 R 227377 CDS NP_820616.1 29654924 1209545 complement(1574545..1575261) 1 NC_002971.3 hypothetical protein 1575261 icmQ 1209545 icmQ Coxiella burnetii RSA 493 hypothetical protein NP_820616.1 1574545 R 227377 CDS YP_002333017.1 215919217 7065883 complement(1575258..1575407) 1 NC_002971.3 hypothetical protein 1575407 7065883 CBU_1634a Coxiella burnetii RSA 493 hypothetical protein YP_002333017.1 1575258 R 227377 CDS NP_820617.1 29654925 1209546 1575523..1575696 1 NC_002971.3 hypothetical protein 1575696 1209546 CBU_1635 Coxiella burnetii RSA 493 hypothetical protein NP_820617.1 1575523 D 227377 CDS NP_820618.1 29654926 1209547 complement(1576035..1577210) 1 NC_002971.3 hypothetical protein 1577210 1209547 CBU_1636 Coxiella burnetii RSA 493 hypothetical protein NP_820618.1 1576035 R 227377 CDS NP_820620.1 29654928 1209549 complement(1577295..1578500) 1 NC_002971.3 ATPase 1578500 1209549 CBU_1638 Coxiella burnetii RSA 493 ATPase NP_820620.1 1577295 R 227377 CDS NP_820621.1 29654929 1209550 complement(1578612..1579808) 1 NC_002971.3 hypothetical protein 1579808 1209550 CBU_1639 Coxiella burnetii RSA 493 hypothetical protein NP_820621.1 1578612 R 227377 CDS YP_002333018.1 215919218 1209551 complement(1580306..1581400) 1 NC_002971.3 transposase 1581400 1209551 CBU_1639c Coxiella burnetii RSA 493 transposase YP_002333018.1 1580306 R 227377 CDS NP_820623.1 29654931 1209552 1581517..1581774 1 NC_002971.3 IcmT protein 1581774 icmT 1209552 icmT Coxiella burnetii RSA 493 IcmT protein NP_820623.1 1581517 D 227377 CDS NP_820624.1 29654932 1209553 1581774..1582112 1 NC_002971.3 IcmS protein 1582112 icmS 1209553 icmS Coxiella burnetii RSA 493 IcmS protein NP_820624.1 1581774 D 227377 CDS NP_820625.2 215919219 1209554 1582269..1582778 1 NC_002971.3 DotD 1582778 dotD 1209554 dotD Coxiella burnetii RSA 493 DotD NP_820625.2 1582269 D 227377 CDS NP_820626.1 29654934 1209555 1582781..1583605 1 NC_002971.3 DotC 1583605 dotC 1209555 dotC Coxiella burnetii RSA 493 DotC NP_820626.1 1582781 D 227377 CDS NP_820627.1 29654935 1209556 1583643..1584761 1 NC_002971.3 Dot/Icm secretion system ATPase DotB 1584761 dotB 1209556 dotB Coxiella burnetii RSA 493 Dot/Icm secretion system ATPase DotB NP_820627.1 1583643 D 227377 CDS NP_820628.1 29654936 1209557 1584768..1586102 1 NC_002971.3 transporter 1586102 1209557 CBU_1646 Coxiella burnetii RSA 493 transporter NP_820628.1 1584768 D 227377 CDS NP_820629.1 29654937 1209558 complement(1586424..1586519) 1 NC_002971.3 hypothetical protein 1586519 1209558 CBU_1647 Coxiella burnetii RSA 493 hypothetical protein NP_820629.1 1586424 R 227377 CDS NP_820630.2 215919220 1209559 complement(1586574..1589018) 1 NC_002971.3 DotA protein 1589018 dotaA 1209559 dotaA Coxiella burnetii RSA 493 DotA protein NP_820630.2 1586574 R 227377 CDS NP_820631.2 215919221 1209560 complement(1589015..1589509) 1 NC_002971.3 hypothetical protein 1589509 icmV 1209560 icmV Coxiella burnetii RSA 493 hypothetical protein NP_820631.2 1589015 R 227377 CDS NP_820632.1 29654940 1209561 1589699..1590148 1 NC_002971.3 IcmW 1590148 icmW 1209561 icmW Coxiella burnetii RSA 493 IcmW NP_820632.1 1589699 D 227377 CDS NP_820633.1 29654941 1209562 1590145..1590603 1 NC_002971.3 hypothetical protein 1590603 1209562 CBU_1651 Coxiella burnetii RSA 493 hypothetical protein NP_820633.1 1590145 D 227377 CDS NP_820634.1 29654942 1209563 1590619..1591749 1 NC_002971.3 IcmX 1591749 icmX 1209563 icmX Coxiella burnetii RSA 493 IcmX NP_820634.1 1590619 D 227377 CDS YP_002333019.1 215919222 7065886 1592465..1592647 1 NC_002971.3 virulence-associated protein C 1592647 7065886 CBU_1653a Coxiella burnetii RSA 493 virulence-associated protein C YP_002333019.1 1592465 D 227377 CDS NP_820637.2 215919223 1209566 complement(1592672..1594162) 1 NC_002971.3 'catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose'; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 1594162 rfaE 1209566 rfaE Coxiella burnetii RSA 493 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase NP_820637.2 1592672 R 227377 CDS NP_820638.1 29654946 1209567 complement(1594170..1594271) 1 NC_002971.3 hypothetical protein 1594271 1209567 CBU_1656 Coxiella burnetii RSA 493 hypothetical protein NP_820638.1 1594170 R 227377 CDS NP_820639.1 29654947 1209568 complement(1594438..1595202) 1 NC_002971.3 alpha-L-glycero-D-manno-heptose beta-1,4-glucosyltransferase 1595202 1209568 CBU_1657 Coxiella burnetii RSA 493 alpha-L-glycero-D-manno-heptose beta-1,4-glucosyltransferase NP_820639.1 1594438 R 227377 CDS NP_820640.1 29654948 1209569 complement(1595243..1596328) 1 NC_002971.3 hypothetical protein 1596328 1209569 CBU_1658 Coxiella burnetii RSA 493 hypothetical protein NP_820640.1 1595243 R 227377 CDS NP_820641.2 215919224 1209570 1596377..1597687 1 NC_002971.3 O-antigen ligase 1597687 1209570 CBU_1659 Coxiella burnetii RSA 493 O-antigen ligase NP_820641.2 1596377 D 227377 CDS NP_820642.1 29654950 1209571 1597684..1598568 1 NC_002971.3 hypothetical protein 1598568 1209571 CBU_1660 Coxiella burnetii RSA 493 hypothetical protein NP_820642.1 1597684 D 227377 CDS NP_820643.1 29654951 1209572 complement(1598553..1599584) 1 NC_002971.3 lipopolysaccharide heptosyltransferase II 1599584 rfaF 1209572 rfaF Coxiella burnetii RSA 493 lipopolysaccharide heptosyltransferase II NP_820643.1 1598553 R 227377 CDS NP_820644.2 215919225 1209573 complement(1599588..1599794) 1 NC_002971.3 hypothetical protein 1599794 1209573 CBU_1662 Coxiella burnetii RSA 493 hypothetical protein NP_820644.2 1599588 R 227377 CDS NP_820645.1 29654953 1209574 complement(1599855..1599986) 1 NC_002971.3 hypothetical protein 1599986 1209574 CBU_1663 Coxiella burnetii RSA 493 hypothetical protein NP_820645.1 1599855 R 227377 CDS NP_820646.1 29654954 1209575 1600057..1600650 1 NC_002971.3 hypothetical protein 1600650 1209575 CBU_1664 Coxiella burnetii RSA 493 hypothetical protein NP_820646.1 1600057 D 227377 CDS NP_820647.1 29654955 1209576 complement(1600647..1602386) 1 NC_002971.3 hypothetical protein 1602386 1209576 CBU_1665 Coxiella burnetii RSA 493 hypothetical protein NP_820647.1 1600647 R 227377 CDS NP_820651.1 29654959 1209580 complement(1604402..1605460) 1 NC_002971.3 RNA polymerase sigma factor 1605460 rpoS 1209580 rpoS Coxiella burnetii RSA 493 RNA polymerase sigma factor NP_820651.1 1604402 R 227377 CDS NP_820652.1 29654960 1209581 complement(1605540..1606232) 1 NC_002971.3 lipoprotein NlpD 1606232 1209581 CBU_1670 Coxiella burnetii RSA 493 lipoprotein NlpD NP_820652.1 1605540 R 227377 CDS NP_820653.2 215919226 1209582 complement(1606234..1607010) 1 NC_002971.3 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 1607010 surE 1209582 surE Coxiella burnetii RSA 493 stationary phase survival protein SurE NP_820653.2 1606234 R 227377 CDS NP_820655.1 29654963 1209584 complement(1607079..1607348) 1 NC_002971.3 cell division protein ftsB 1607348 ftsB 1209584 ftsB Coxiella burnetii RSA 493 cell division protein ftsB NP_820655.1 1607079 R 227377 CDS NP_820656.1 29654964 1209585 complement(1607355..1608641) 1 NC_002971.3 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1608641 eno 1209585 eno Coxiella burnetii RSA 493 phosphopyruvate hydratase NP_820656.1 1607355 R 227377 CDS NP_820657.1 29654965 1209586 complement(1608798..1609640) 1 NC_002971.3 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1609640 kdsA 1209586 kdsA Coxiella burnetii RSA 493 2-dehydro-3-deoxyphosphooctonate aldolase NP_820657.1 1608798 R 227377 CDS YP_002333020.1 215919227 7065936 1609679..1609834 1 NC_002971.3 hypothetical protein 1609834 7065936 CBU_1675a Coxiella burnetii RSA 493 hypothetical protein YP_002333020.1 1609679 D 227377 CDS NP_820658.1 29654966 1209587 complement(1609953..1611038) 1 NC_002971.3 hypothetical protein 1611038 1209587 CBU_1676 Coxiella burnetii RSA 493 hypothetical protein NP_820658.1 1609953 R 227377 CDS NP_820659.1 29654967 1209588 complement(1611108..1611542) 1 NC_002971.3 hemerythrin HHE cation binding domain protein 1611542 1209588 CBU_1677 Coxiella burnetii RSA 493 hemerythrin HHE cation binding domain protein NP_820659.1 1611108 R 227377 CDS NP_820660.1 29654968 1209589 1611675..1612187 1 NC_002971.3 diamine N-acetyltransferase 1612187 speG 1209589 speG Coxiella burnetii RSA 493 diamine N-acetyltransferase NP_820660.1 1611675 D 227377 CDS NP_820663.2 215919228 1209592 complement(1613773..1614069) 1 NC_002971.3 hypothetical protein 1614069 1209592 CBU_1681 Coxiella burnetii RSA 493 hypothetical protein NP_820663.2 1613773 R 227377 CDS NP_820664.1 29654972 1209593 complement(1614110..1615777) 1 NC_002971.3 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1615777 pyrG 1209593 pyrG Coxiella burnetii RSA 493 CTP synthetase NP_820664.1 1614110 R 227377 CDS NP_820665.1 29654973 1209594 complement(1615812..1615943) 1 NC_002971.3 hypothetical protein 1615943 1209594 CBU_1683 Coxiella burnetii RSA 493 hypothetical protein NP_820665.1 1615812 R 227377 CDS NP_820666.1 29654974 1209595 1616113..1616205 1 NC_002971.3 hypothetical protein 1616205 1209595 CBU_1684 Coxiella burnetii RSA 493 hypothetical protein NP_820666.1 1616113 D 227377 CDS NP_820667.1 29654975 1209596 1616280..1617701 1 NC_002971.3 hypothetical protein 1617701 1209596 CBU_1685 Coxiella burnetii RSA 493 hypothetical protein NP_820667.1 1616280 D 227377 CDS NP_820668.1 29654976 1209597 1617723..1620044 1 NC_002971.3 hypothetical protein 1620044 1209597 CBU_1686 Coxiella burnetii RSA 493 hypothetical protein NP_820668.1 1617723 D 227377 CDS NP_820669.1 29654977 1209599 complement(1622557..1623123) 1 NC_002971.3 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1623123 dcd 1209599 dcd Coxiella burnetii RSA 493 deoxycytidine triphosphate deaminase NP_820669.1 1622557 R 227377 CDS NP_820670.1 29654978 1209600 complement(1623123..1624043) 1 NC_002971.3 NifH/FrxC domain protein 1624043 apbC 1209600 apbC Coxiella burnetii RSA 493 NifH/FrxC domain protein NP_820670.1 1623123 R 227377 CDS NP_820671.1 29654979 1209601 1624269..1624370 1 NC_002971.3 hypothetical protein 1624370 1209601 CBU_1690 Coxiella burnetii RSA 493 hypothetical protein NP_820671.1 1624269 D 227377 CDS NP_820672.1 29654980 1209602 complement(1624477..1624803) 1 NC_002971.3 DNA-binding protein 1624803 1209602 CBU_1691 Coxiella burnetii RSA 493 DNA-binding protein NP_820672.1 1624477 R 227377 CDS NP_820673.1 29654981 1209603 complement(1624796..1624966) 1 NC_002971.3 phage derived Gp49-like protein 1624966 1209603 CBU_1692 Coxiella burnetii RSA 493 phage derived Gp49-like protein NP_820673.1 1624796 R 227377 CDS YP_002333021.1 215919229 7065921 1625039..1625164 1 NC_002971.3 hypothetical protein 1625164 7065921 CBU_1692a Coxiella burnetii RSA 493 hypothetical protein YP_002333021.1 1625039 D 227377 CDS NP_820676.1 29654984 1209606 1627148..1628788 1 NC_002971.3 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1628788 metG 1209606 metG Coxiella burnetii RSA 493 methionyl-tRNA synthetase NP_820676.1 1627148 D 227377 CDS NP_820677.1 29654985 1209607 1628781..1629422 1 NC_002971.3 4Fe-4S ferredoxin 1629422 rnfB 1209607 rnfB Coxiella burnetii RSA 493 4Fe-4S ferredoxin NP_820677.1 1628781 D 227377 CDS NP_820678.1 29654986 1209608 1629409..1630065 1 NC_002971.3 endonuclease III 1630065 nth 1209608 nth Coxiella burnetii RSA 493 endonuclease III NP_820678.1 1629409 D 227377 CDS NP_820679.1 29654987 1209609 complement(1630040..1631299) 1 NC_002971.3 ATPase 1631299 1209609 CBU_1698 Coxiella burnetii RSA 493 ATPase NP_820679.1 1630040 R 227377 CDS NP_820680.1 29654988 1209610 complement(1631303..1632859) 1 NC_002971.3 hypothetical protein 1632859 1209610 CBU_1699 Coxiella burnetii RSA 493 hypothetical protein NP_820680.1 1631303 R 227377 CDS YP_002333022.1 215919230 1209611 1633010..1634104 1 NC_002971.3 transposase 1634104 1209611 CBU_1699a Coxiella burnetii RSA 493 transposase YP_002333022.1 1633010 D 227377 CDS YP_002333023.1 215919231 7065917 complement(1634101..1634397) 1 NC_002971.3 hypothetical protein 1634397 7065917 CBU_1699b Coxiella burnetii RSA 493 hypothetical protein YP_002333023.1 1634101 R 227377 CDS NP_820682.1 29654990 1209612 1634514..1635920 1 NC_002971.3 hypothetical protein 1635920 1209612 CBU_1701 Coxiella burnetii RSA 493 hypothetical protein NP_820682.1 1634514 D 227377 CDS NP_820683.1 29654991 1209613 complement(1635995..1636129) 1 NC_002971.3 hypothetical protein 1636129 1209613 CBU_1702 Coxiella burnetii RSA 493 hypothetical protein NP_820683.1 1635995 R 227377 CDS NP_820684.1 29654992 1209614 1636209..1637264 1 NC_002971.3 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1637264 pyrC 1209614 pyrC Coxiella burnetii RSA 493 dihydroorotase NP_820684.1 1636209 D 227377 CDS NP_820685.1 29654993 1209615 1637251..1637925 1 NC_002971.3 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1637925 rnt 1209615 rnt Coxiella burnetii RSA 493 ribonuclease T NP_820685.1 1637251 D 227377 CDS NP_820686.2 215919232 1209616 complement(1637922..1638311) 1 NC_002971.3 hypothetical protein 1638311 1209616 CBU_1705 Coxiella burnetii RSA 493 hypothetical protein NP_820686.2 1637922 R 227377 CDS NP_820687.1 29654995 1209617 complement(1638369..1638971) 1 NC_002971.3 anti-oxidant AhpCTSA family protein 1638971 1209617 CBU_1706 Coxiella burnetii RSA 493 anti-oxidant AhpCTSA family protein NP_820687.1 1638369 R 227377 CDS NP_820688.1 29654996 1209618 complement(1639009..1639101) 1 NC_002971.3 hypothetical protein 1639101 1209618 CBU_1707 Coxiella burnetii RSA 493 hypothetical protein NP_820688.1 1639009 R 227377 CDS NP_820689.1 29654997 1209619 1639188..1639769 1 NC_002971.3 superoxide dismutase 1639769 sodB 1209619 sodB Coxiella burnetii RSA 493 superoxide dismutase NP_820689.1 1639188 D 227377 CDS NP_820690.1 29654998 1209620 1639771..1640490 1 NC_002971.3 'catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis'; dihydrodipicolinate reductase 1640490 dapB 1209620 dapB Coxiella burnetii RSA 493 dihydrodipicolinate reductase NP_820690.1 1639771 D 227377 CDS NP_820691.1 29654999 1209621 1640493..1640930 1 NC_002971.3 hypothetical protein 1640930 1209621 CBU_1710 Coxiella burnetii RSA 493 hypothetical protein NP_820691.1 1640493 D 227377 CDS NP_820692.1 29655000 1209622 1641089..1641277 1 NC_002971.3 hypothetical protein 1641277 1209622 CBU_1711 Coxiella burnetii RSA 493 hypothetical protein NP_820692.1 1641089 D 227377 CDS NP_820693.1 29655001 1209623 1641294..1641584 1 NC_002971.3 GIY-YIG catalytic domain-containing protein 1641584 1209623 CBU_1712 Coxiella burnetii RSA 493 GIY-YIG catalytic domain-containing protein NP_820693.1 1641294 D 227377 CDS NP_820694.1 29655002 1209624 complement(1641681..1643156) 1 NC_002971.3 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1643156 1209624 CBU_1713 Coxiella burnetii RSA 493 glycine dehydrogenase subunit 2 NP_820694.1 1641681 R 227377 CDS NP_820695.1 29655003 1209625 complement(1643224..1644564) 1 NC_002971.3 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 1644564 1209625 CBU_1714 Coxiella burnetii RSA 493 glycine dehydrogenase subunit 1 NP_820695.1 1643224 R 227377 CDS NP_820696.1 29655004 1209626 complement(1644567..1644959) 1 NC_002971.3 'part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor'; glycine cleavage system protein H 1644959 gcvH 1209626 gcvH Coxiella burnetii RSA 493 glycine cleavage system protein H NP_820696.1 1644567 R 227377 CDS NP_820697.2 215919234 1209627 complement(1644970..1646145) 1 NC_002971.3 'catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein'; glycine cleavage system aminomethyltransferase T 1646145 gcvT 1209627 gcvT Coxiella burnetii RSA 493 glycine cleavage system aminomethyltransferase T NP_820697.2 1644970 R 227377 CDS YP_002333024.1 215919233 1209628 1646136..1647230 1 NC_002971.3 transposase 1647230 1209628 CBU_1716a Coxiella burnetii RSA 493 transposase YP_002333024.1 1646136 D 227377 CDS YP_002333025.1 215919235 7065903 complement(1647227..1647538) 1 NC_002971.3 hypothetical protein 1647538 7065903 CBU_1716b Coxiella burnetii RSA 493 hypothetical protein YP_002333025.1 1647227 R 227377 CDS NP_820699.1 29655007 1209629 complement(1647622..1649280) 1 NC_002971.3 '60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth'; molecular chaperone GroEL 1649280 groEL 1209629 groEL Coxiella burnetii RSA 493 molecular chaperone GroEL NP_820699.1 1647622 R 227377 CDS YP_009001906.1 584120664 1209630 complement(1649308..1649658) 1 NC_002971.3 10 KDa chaperonin GROES 1649658 groES 1209630 groES Coxiella burnetii RSA 493 10 KDa chaperonin GROES YP_009001906.1 1649308 R 227377 CDS NP_820701.2 215919237 1209631 1649719..1652472 1 NC_002971.3 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1652472 acnA 1209631 acnA Coxiella burnetii RSA 493 aconitate hydratase NP_820701.2 1649719 D 227377 CDS NP_820702.1 29655010 1209632 1652483..1653193 1 NC_002971.3 hypothetical protein 1653193 1209632 CBU_1721 Coxiella burnetii RSA 493 hypothetical protein NP_820702.1 1652483 D 227377 CDS NP_820704.2 215919238 1209634 1655090..1656982 1 NC_002971.3 thiol:disulfide interchange protein 1656982 dsbD 1209634 dsbD Coxiella burnetii RSA 493 thiol:disulfide interchange protein NP_820704.2 1655090 D 227377 CDS NP_820705.1 29655013 1209635 complement(1656991..1659234) 1 NC_002971.3 hypothetical protein 1659234 1209635 CBU_1724 Coxiella burnetii RSA 493 hypothetical protein NP_820705.1 1656991 R 227377 CDS YP_002333026.1 215919239 7065899 complement(1659667..1659813) 1 NC_002971.3 hypothetical protein 1659813 7065899 CBU_1724a Coxiella burnetii RSA 493 hypothetical protein YP_002333026.1 1659667 R 227377 CDS NP_820706.1 29655014 1209636 1659823..1660287 1 NC_002971.3 biotin carboxyl carrier protein of acetyl-CoA carboxylase 1660287 accB 1209636 accB Coxiella burnetii RSA 493 biotin carboxyl carrier protein of acetyl-CoA carboxylase NP_820706.1 1659823 D 227377 CDS NP_820707.1 29655015 1209637 1660294..1661640 1 NC_002971.3 biotin carboxylase 1661640 accC 1209637 accC Coxiella burnetii RSA 493 biotin carboxylase NP_820707.1 1660294 D 227377 CDS NP_820708.1 29655016 1209638 complement(1661692..1662702) 1 NC_002971.3 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 1662702 arcB 1209638 arcB Coxiella burnetii RSA 493 ornithine cyclodeaminase NP_820708.1 1661692 R 227377 CDS NP_820709.1 29655017 1209639 complement(1662695..1663312) 1 NC_002971.3 nicotinamide mononucleotide transporter 1663312 1209639 CBU_1728 Coxiella burnetii RSA 493 nicotinamide mononucleotide transporter NP_820709.1 1662695 R 227377 CDS NP_820710.2 215919240 1209640 complement(1663347..1664297) 1 NC_002971.3 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1664297 hemF 1209640 hemF Coxiella burnetii RSA 493 coproporphyrinogen III oxidase NP_820710.2 1663347 R 227377 CDS NP_820711.1 29655019 1209641 complement(1664387..1665163) 1 NC_002971.3 HAD hydrolase 1665163 1209641 CBU_1730 Coxiella burnetii RSA 493 HAD hydrolase NP_820711.1 1664387 R 227377 CDS NP_820712.1 29655020 1209643 1666586..1667752 1 NC_002971.3 D-3-phosphoglycerate dehydrogenase 1667752 1209643 CBU_1732 Coxiella burnetii RSA 493 D-3-phosphoglycerate dehydrogenase NP_820712.1 1666586 D 227377 CDS NP_820713.1 29655021 1209644 1667895..1669796 1 NC_002971.3 hypothetical protein 1669796 1209644 CBU_1733 Coxiella burnetii RSA 493 hypothetical protein NP_820713.1 1667895 D 227377 CDS NP_820714.1 29655022 1209645 complement(1669895..1670608) 1 NC_002971.3 chromosome replication initiator DnaA 1670608 1209645 CBU_1734 Coxiella burnetii RSA 493 chromosome replication initiator DnaA NP_820714.1 1669895 R 227377 CDS NP_820715.2 215919241 1209646 complement(1670611..1671756) 1 NC_002971.3 hypothetical protein 1671756 1209646 CBU_1735 Coxiella burnetii RSA 493 hypothetical protein NP_820715.2 1670611 R 227377 CDS NP_820716.2 215919242 1209647 1671784..1672875 1 NC_002971.3 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1672875 purM 1209647 purM Coxiella burnetii RSA 493 phosphoribosylaminoimidazole synthetase NP_820716.2 1671784 D 227377 CDS NP_820717.1 29655025 1209648 1672872..1673519 1 NC_002971.3 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1673519 purN 1209648 purN Coxiella burnetii RSA 493 phosphoribosylglycinamide formyltransferase NP_820717.1 1672872 D 227377 CDS NP_820718.1 29655026 1209649 1673605..1673943 1 NC_002971.3 integration host factor beta-subunit 1673943 hipB 1209649 hipB Coxiella burnetii RSA 493 integration host factor beta-subunit NP_820718.1 1673605 D 227377 CDS NP_820719.1 29655027 1209650 complement(1673909..1674766) 1 NC_002971.3 tetrapyrrole methylase domain-containing protein 1674766 1209650 CBU_1739 Coxiella burnetii RSA 493 tetrapyrrole methylase domain-containing protein NP_820719.1 1673909 R 227377 CDS NP_820720.1 29655028 1209651 complement(1674848..1675015) 1 NC_002971.3 hypothetical protein 1675015 1209651 CBU_1740 Coxiella burnetii RSA 493 hypothetical protein NP_820720.1 1674848 R 227377 CDS NP_820721.1 29655029 1209652 1675029..1676219 1 NC_002971.3 lipoprotein 1676219 1209652 CBU_1741 Coxiella burnetii RSA 493 lipoprotein NP_820721.1 1675029 D 227377 CDS NP_820722.1 29655030 1209653 1676269..1676631 1 NC_002971.3 hypothetical protein 1676631 1209653 CBU_1742 Coxiella burnetii RSA 493 hypothetical protein NP_820722.1 1676269 D 227377 CDS NP_820723.1 29655031 1209654 1676637..1677236 1 NC_002971.3 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 1677236 gmhA 1209654 gmhA Coxiella burnetii RSA 493 phosphoheptose isomerase NP_820723.1 1676637 D 227377 CDS NP_820724.1 29655032 1209655 1677236..1677811 1 NC_002971.3 phospholipid-binding liporotein 1677811 1209655 CBU_1744 Coxiella burnetii RSA 493 phospholipid-binding liporotein NP_820724.1 1677236 D 227377 CDS NP_820725.1 29655033 1209656 complement(1678221..1678913) 1 NC_002971.3 peptidase, M50 family protein 1678913 1209656 CBU_1745 Coxiella burnetii RSA 493 peptidase, M50 family protein NP_820725.1 1678221 R 227377 CDS NP_820726.2 215919243 1209657 complement(1679001..1679405) 1 NC_002971.3 ClpXP protease specificity-enhancing factor 1679405 sspB 1209657 sspB Coxiella burnetii RSA 493 ClpXP protease specificity-enhancing factor NP_820726.2 1679001 R 227377 CDS NP_820727.2 215919244 1209658 complement(1679407..1680069) 1 NC_002971.3 stringent starvation protein A 1680069 sspA 1209658 sspA Coxiella burnetii RSA 493 stringent starvation protein A NP_820727.2 1679407 R 227377 CDS NP_820728.1 29655036 1209659 complement(1680100..1680519) 1 NC_002971.3 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1680519 rpsI 1209659 rpsI Coxiella burnetii RSA 493 30S ribosomal protein S9 NP_820728.1 1680100 R 227377 CDS NP_820729.1 29655037 1209660 complement(1680538..1680966) 1 NC_002971.3 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1680966 rplM 1209660 rplM Coxiella burnetii RSA 493 50S ribosomal protein L13 NP_820729.1 1680538 R 227377 CDS YP_008992036.1 570699742 18126244 1681196..1681645 1 NC_002971.3 DNA-binding protein; hypothetical protein 1681645 18126244 CBU_1749b Coxiella burnetii RSA 493 hypothetical protein YP_008992036.1 1681196 D 227377 CDS NP_820731.1 29655039 1209662 1681753..1683015 1 NC_002971.3 hypothetical protein 1683015 1209662 CBU_1751 Coxiella burnetii RSA 493 hypothetical protein NP_820731.1 1681753 D 227377 CDS NP_820732.1 29655040 1209663 1683051..1684289 1 NC_002971.3 hypothetical protein 1684289 1209663 CBU_1752 Coxiella burnetii RSA 493 hypothetical protein NP_820732.1 1683051 D 227377 CDS NP_820733.1 29655041 1209664 1684363..1684779 1 NC_002971.3 hypothetical protein 1684779 1209664 CBU_1753 Coxiella burnetii RSA 493 hypothetical protein NP_820733.1 1684363 D 227377 CDS NP_820734.1 29655042 1209665 complement(1684801..1685397) 1 NC_002971.3 hypothetical protein 1685397 1209665 CBU_1754 Coxiella burnetii RSA 493 hypothetical protein NP_820734.1 1684801 R 227377 CDS NP_820735.1 29655043 1209666 complement(1685407..1685532) 1 NC_002971.3 hypothetical protein 1685532 1209666 CBU_1755 Coxiella burnetii RSA 493 hypothetical protein NP_820735.1 1685407 R 227377 CDS NP_820736.1 29655044 1209667 1685579..1686760 1 NC_002971.3 Bcr/CflA subfamily drug resistance transporter 1686760 1209667 CBU_1756 Coxiella burnetii RSA 493 Bcr/CflA subfamily drug resistance transporter NP_820736.1 1685579 D 227377 CDS YP_002333028.1 215919246 1209670 1689450..1690514 1 NC_002971.3 transposase 1690514 1209670 CBU_1758a Coxiella burnetii RSA 493 transposase YP_002333028.1 1689450 D 227377 CDS YP_002333029.1 215919247 7065918 complement(1690511..1690855) 1 NC_002971.3 hypothetical protein 1690855 7065918 CBU_1758b Coxiella burnetii RSA 493 hypothetical protein YP_002333029.1 1690511 R 227377 CDS NP_820740.1 29655048 1209671 1690932..1691045 1 NC_002971.3 hypothetical protein 1691045 1209671 CBU_1760 Coxiella burnetii RSA 493 hypothetical protein NP_820740.1 1690932 D 227377 CDS NP_820741.1 29655049 1209672 complement(1691109..1693082) 1 NC_002971.3 two component system histidine kinase 1693082 1209672 CBU_1761 Coxiella burnetii RSA 493 two component system histidine kinase NP_820741.1 1691109 R 227377 CDS NP_820742.1 29655050 1209673 complement(1693136..1694518) 1 NC_002971.3 FAD dependent oxidoreductase 1694518 1209673 CBU_1762 Coxiella burnetii RSA 493 FAD dependent oxidoreductase NP_820742.1 1693136 R 227377 CDS NP_820743.2 215919248 1209674 1694676..1696010 1 NC_002971.3 ATPase 1696010 1209674 CBU_1763 Coxiella burnetii RSA 493 ATPase NP_820743.2 1694676 D 227377 CDS NP_820744.1 29655052 1209675 complement(1696034..1696141) 1 NC_002971.3 hypothetical protein 1696141 1209675 CBU_1764 Coxiella burnetii RSA 493 hypothetical protein NP_820744.1 1696034 R 227377 CDS YP_002333030.1 215919249 7065878 1696140..1696496 1 NC_002971.3 hypothetical protein 1696496 7065878 CBU_1764a Coxiella burnetii RSA 493 hypothetical protein YP_002333030.1 1696140 D 227377 CDS NP_820745.1 29655053 1209676 complement(1696622..1696840) 1 NC_002971.3 hypothetical protein 1696840 1209676 CBU_1765 Coxiella burnetii RSA 493 hypothetical protein NP_820745.1 1696622 R 227377 CDS NP_820746.1 29655054 1209677 complement(1696840..1699290) 1 NC_002971.3 ferrous iron transport protein B 1699290 feoB 1209677 feoB Coxiella burnetii RSA 493 ferrous iron transport protein B NP_820746.1 1696840 R 227377 CDS NP_820747.2 215919250 1209678 complement(1699291..1699560) 1 NC_002971.3 ferrous iron transport protein A 1699560 feoA 1209678 feoA Coxiella burnetii RSA 493 ferrous iron transport protein A NP_820747.2 1699291 R 227377 CDS NP_820748.1 29655056 1209679 complement(1699622..1700083) 1 NC_002971.3 hypothetical protein 1700083 1209679 CBU_1768 Coxiella burnetii RSA 493 hypothetical protein NP_820748.1 1699622 R 227377 CDS NP_820749.1 29655057 1209680 complement(1700146..1700763) 1 NC_002971.3 alpha/beta hydrolase 1700763 1209680 CBU_1769 Coxiella burnetii RSA 493 alpha/beta hydrolase NP_820749.1 1700146 R 227377 CDS NP_820750.2 215919251 1209681 complement(1700867..1702183) 1 NC_002971.3 ABC transporter ATP-binding protein 1702183 1209681 CBU_1770 Coxiella burnetii RSA 493 ABC transporter ATP-binding protein NP_820750.2 1700867 R 227377 CDS NP_820751.1 29655059 1209682 complement(1702281..1704026) 1 NC_002971.3 ABC transporter permease 1704026 1209682 CBU_1771 Coxiella burnetii RSA 493 ABC transporter permease NP_820751.1 1702281 R 227377 CDS NP_820752.1 29655060 1209683 complement(1704261..1704878) 1 NC_002971.3 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1704878 engB 1209683 engB Coxiella burnetii RSA 493 ribosome biogenesis GTP-binding protein YsxC NP_820752.1 1704261 R 227377 CDS NP_820757.1 29655065 1209688 complement(1706638..1706823) 1 NC_002971.3 hypothetical protein 1706823 1209688 CBU_1777 Coxiella burnetii RSA 493 hypothetical protein NP_820757.1 1706638 R 227377 CDS NP_820758.1 29655066 1209689 complement(1706887..1707978) 1 NC_002971.3 'class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis'; fructose-1,6-bisphosphate aldolase 1707978 fbaA 1209689 fbaA Coxiella burnetii RSA 493 fructose-1,6-bisphosphate aldolase NP_820758.1 1706887 R 227377 CDS NP_820760.2 215919252 1209691 1708215..1709804 1 NC_002971.3 hypothetical protein 1709804 1209691 CBU_1780 Coxiella burnetii RSA 493 hypothetical protein NP_820760.2 1708215 D 227377 CDS NP_820761.2 215919253 1209692 complement(1709808..1711262) 1 NC_002971.3 pyruvate kinase 1711262 pyk 1209692 pyk Coxiella burnetii RSA 493 pyruvate kinase NP_820761.2 1709808 R 227377 CDS NP_820762.2 215919254 1209693 complement(1711249..1712463) 1 NC_002971.3 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1712463 pgk 1209693 pgk Coxiella burnetii RSA 493 phosphoglycerate kinase NP_820762.2 1711249 R 227377 CDS NP_820763.1 29655071 1209694 complement(1712535..1713539) 1 NC_002971.3 glyceraldehyde 3-phosphate dehydrogenase 1713539 gap 1209694 gap Coxiella burnetii RSA 493 glyceraldehyde 3-phosphate dehydrogenase NP_820763.1 1712535 R 227377 CDS NP_820764.2 215919255 1209695 complement(1713554..1715572) 1 NC_002971.3 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase'; transketolase 1715572 tkt 1209695 tkt Coxiella burnetii RSA 493 transketolase NP_820764.2 1713554 R 227377 CDS NP_820765.2 215919256 1209696 1715696..1716790 1 NC_002971.3 IS1111A transposase 1716790 1209696 CBU_1785 Coxiella burnetii RSA 493 IS1111A transposase NP_820765.2 1715696 D 227377 CDS YP_002333031.1 215919257 7065902 complement(1716787..1717059) 1 NC_002971.3 hypothetical protein 1717059 7065902 CBU_1785a Coxiella burnetii RSA 493 hypothetical protein YP_002333031.1 1716787 R 227377 CDS NP_820766.2 215919258 1209697 complement(1717132..1718334) 1 NC_002971.3 ATPase 1718334 1209697 CBU_1786 Coxiella burnetii RSA 493 ATPase NP_820766.2 1717132 R 227377 CDS NP_820767.1 29655075 1209698 1718371..1720206 1 NC_002971.3 glutamine-fructose-6-phosphate transaminase (isomerizing) 1720206 glmS 1209698 glmS Coxiella burnetii RSA 493 glutamine-fructose-6-phosphate transaminase (isomerizing) NP_820767.1 1718371 D 227377 CDS NP_820768.2 215919259 1209699 1720203..1720793 1 NC_002971.3 hypothetical protein 1720793 1209699 CBU_1788 Coxiella burnetii RSA 493 hypothetical protein NP_820768.2 1720203 D 227377 CDS NP_820769.1 29655077 1209700 complement(1721182..1722048) 1 NC_002971.3 SMP-30/CGR1 family protein 1722048 1209700 CBU_1789 Coxiella burnetii RSA 493 SMP-30/CGR1 family protein NP_820769.1 1721182 R 227377 CDS NP_820770.1 29655078 1209701 1722228..1724132 1 NC_002971.3 hypothetical protein 1724132 1209701 CBU_1790 Coxiella burnetii RSA 493 hypothetical protein NP_820770.1 1722228 D 227377 CDS NP_820773.2 215919260 1209705 1725445..1726263 1 NC_002971.3 hypothetical protein 1726263 1209705 CBU_1794 Coxiella burnetii RSA 493 hypothetical protein NP_820773.2 1725445 D 227377 CDS NP_820774.2 215919261 1209706 complement(1726293..1729001) 1 NC_002971.3 DNA polymerase I 1729001 polI 1209706 polI Coxiella burnetii RSA 493 DNA polymerase I NP_820774.2 1726293 R 227377 CDS NP_820775.1 29655083 1209707 1729052..1730680 1 NC_002971.3 amino acid permease 1730680 1209707 CBU_1796 Coxiella burnetii RSA 493 amino acid permease NP_820775.1 1729052 D 227377 CDS NP_820776.1 29655084 1209708 1730685..1731125 1 NC_002971.3 thioesterase 1731125 1209708 CBU_1797 Coxiella burnetii RSA 493 thioesterase NP_820776.1 1730685 D 227377 CDS NP_820777.1 29655085 1209709 1731254..1733197 1 NC_002971.3 hypothetical protein 1733197 1209709 CBU_1798 Coxiella burnetii RSA 493 hypothetical protein NP_820777.1 1731254 D 227377 CDS YP_002333032.1 215919262 7065874 1733270..1733728 1 NC_002971.3 cupin 1733728 7065874 CBU_1799a Coxiella burnetii RSA 493 cupin YP_002333032.1 1733270 D 227377 CDS NP_820778.1 29655086 1209710 complement(1733579..1734040) 1 NC_002971.3 acetyltransferase 1734040 1209710 CBU_1799 Coxiella burnetii RSA 493 acetyltransferase NP_820778.1 1733579 R 227377 CDS NP_820779.1 29655087 1209711 complement(1734037..1734795) 1 NC_002971.3 hypothetical protein 1734795 1209711 CBU_1800 Coxiella burnetii RSA 493 hypothetical protein NP_820779.1 1734037 R 227377 CDS NP_820780.2 215919263 1209712 complement(1734804..1735100) 1 NC_002971.3 hypothetical protein 1735100 1209712 CBU_1801 Coxiella burnetii RSA 493 hypothetical protein NP_820780.2 1734804 R 227377 CDS NP_820781.1 29655089 1209713 complement(1735124..1735762) 1 NC_002971.3 hypothetical protein 1735762 1209713 CBU_1802 Coxiella burnetii RSA 493 hypothetical protein NP_820781.1 1735124 R 227377 CDS NP_820782.1 29655090 1209714 1735952..1736080 1 NC_002971.3 hypothetical protein 1736080 1209714 CBU_1803 Coxiella burnetii RSA 493 hypothetical protein NP_820782.1 1735952 D 227377 CDS NP_820783.1 29655091 1209715 1736099..1736353 1 NC_002971.3 LuxR family transcriptional regulator 1736353 1209715 CBU_1804 Coxiella burnetii RSA 493 LuxR family transcriptional regulator NP_820783.1 1736099 D 227377 CDS NP_820784.1 29655092 1209716 1736367..1736750 1 NC_002971.3 LuxR family transcriptional regulator 1736750 1209716 CBU_1805 Coxiella burnetii RSA 493 LuxR family transcriptional regulator NP_820784.1 1736367 D 227377 CDS NP_820785.1 29655093 1209717 complement(1736826..1737113) 1 NC_002971.3 DNA polymerase domain-containing protein 1737113 1209717 CBU_1806 Coxiella burnetii RSA 493 DNA polymerase domain-containing protein NP_820785.1 1736826 R 227377 CDS NP_820787.1 29655095 1209719 complement(1738234..1739448) 1 NC_002971.3 export ABC transporter permease 1739448 1209719 CBU_1808 Coxiella burnetii RSA 493 export ABC transporter permease NP_820787.1 1738234 R 227377 CDS NP_820788.1 29655096 1209720 complement(1739438..1740103) 1 NC_002971.3 ABC transporter ATP-binding protein 1740103 1209720 CBU_1809 Coxiella burnetii RSA 493 ABC transporter ATP-binding protein NP_820788.1 1739438 R 227377 CDS NP_820789.1 29655097 1209721 complement(1740096..1741271) 1 NC_002971.3 ABC transporter substrate-binding protein 1741271 macA 1209721 macA Coxiella burnetii RSA 493 ABC transporter substrate-binding protein NP_820789.1 1740096 R 227377 CDS NP_820790.1 29655098 1209722 complement(1741274..1742797) 1 NC_002971.3 type I secretion outer membrane protein 1742797 1209722 CBU_1811 Coxiella burnetii RSA 493 type I secretion outer membrane protein NP_820790.1 1741274 R 227377 CDS NP_820791.1 29655099 1209723 1742864..1743991 1 NC_002971.3 erythronate-4-phosphate dehydrogenase 1743991 1209723 CBU_1812 Coxiella burnetii RSA 493 erythronate-4-phosphate dehydrogenase NP_820791.1 1742864 D 227377 CDS NP_820792.1 29655100 1209724 1743972..1744100 1 NC_002971.3 hypothetical protein 1744100 1209724 CBU_1813 Coxiella burnetii RSA 493 hypothetical protein NP_820792.1 1743972 D 227377 CDS NP_820793.1 29655101 1209725 1744137..1744850 1 NC_002971.3 hypothetical protein 1744850 1209725 CBU_1814 Coxiella burnetii RSA 493 hypothetical protein NP_820793.1 1744137 D 227377 CDS NP_820794.1 29655102 1209726 complement(1744998..1746986) 1 NC_002971.3 primosomal protein N' 1746986 priA 1209726 priA Coxiella burnetii RSA 493 primosomal protein N' NP_820794.1 1744998 R 227377 CDS NP_820795.1 29655103 1209727 1747058..1747624 1 NC_002971.3 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1747624 efp 1209727 efp Coxiella burnetii RSA 493 elongation factor P NP_820795.1 1747058 D 227377 CDS NP_820796.1 29655104 1209728 1747629..1748594 1 NC_002971.3 lysyl-tRNA synthetase 1748594 1209728 CBU_1817 Coxiella burnetii RSA 493 lysyl-tRNA synthetase NP_820796.1 1747629 D 227377 CDS NP_820797.1 29655105 1209729 1748815..1750260 1 NC_002971.3 hypothetical protein 1750260 1209729 CBU_1818 Coxiella burnetii RSA 493 hypothetical protein NP_820797.1 1748815 D 227377 CDS NP_820798.1 29655106 1209730 1750313..1751446 1 NC_002971.3 hypothetical protein 1751446 1209730 CBU_1819 Coxiella burnetii RSA 493 hypothetical protein NP_820798.1 1750313 D 227377 CDS NP_820799.1 29655107 1209731 complement(1751463..1751987) 1 NC_002971.3 hypothetical protein 1751987 1209731 CBU_1820 Coxiella burnetii RSA 493 hypothetical protein NP_820799.1 1751463 R 227377 CDS NP_820800.1 29655108 1209732 complement(1751990..1752487) 1 NC_002971.3 hypothetical protein 1752487 1209732 CBU_1821 Coxiella burnetii RSA 493 hypothetical protein NP_820800.1 1751990 R 227377 CDS NP_820801.2 215919264 1209733 complement(1752603..1753193) 1 NC_002971.3 Cu-Zn; superoxide dismutase 1753193 sodC 1209733 sodC Coxiella burnetii RSA 493 superoxide dismutase NP_820801.2 1752603 R 227377 CDS NP_820802.1 29655110 1209734 1753253..1754302 1 NC_002971.3 hypothetical protein 1754302 1209734 CBU_1823 Coxiella burnetii RSA 493 hypothetical protein NP_820802.1 1753253 D 227377 CDS NP_820803.1 29655111 1209735 complement(1754311..1754541) 1 NC_002971.3 hypothetical protein 1754541 1209735 CBU_1824 Coxiella burnetii RSA 493 hypothetical protein NP_820803.1 1754311 R 227377 CDS NP_820804.1 29655112 1209736 1754604..1754951 1 NC_002971.3 hypothetical protein 1754951 1209736 CBU_1825 Coxiella burnetii RSA 493 hypothetical protein NP_820804.1 1754604 D 227377 CDS NP_820805.1 29655113 1209737 complement(1754956..1755804) 1 NC_002971.3 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 1755804 psd 1209737 psd Coxiella burnetii RSA 493 phosphatidylserine decarboxylase NP_820805.1 1754956 R 227377 CDS NP_820806.2 215919265 1209738 1755811..1756956 1 NC_002971.3 multifunctional CCA protein 1756956 1209738 CBU_1827 Coxiella burnetii RSA 493 multifunctional CCA protein NP_820806.2 1755811 D 227377 CDS NP_820807.2 215919266 1209739 complement(1756990..1758243) 1 NC_002971.3 hypothetical protein 1758243 1209739 CBU_1828 Coxiella burnetii RSA 493 hypothetical protein NP_820807.2 1756990 R 227377 CDS NP_820808.1 29655116 1209740 1758250..1758882 1 NC_002971.3 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; hypothetical protein 1758882 lolB 1209740 lolB Coxiella burnetii RSA 493 hypothetical protein NP_820808.1 1758250 D 227377 CDS NP_820809.1 29655117 1209742 1759057..1760016 1 NC_002971.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1760016 prsA 1209742 prsA Coxiella burnetii RSA 493 ribose-phosphate pyrophosphokinase NP_820809.1 1759057 D 227377 CDS NP_820810.1 29655118 1209743 1760021..1761469 1 NC_002971.3 hypothetical protein 1761469 1209743 CBU_1831 Coxiella burnetii RSA 493 hypothetical protein NP_820810.1 1760021 D 227377 CDS YP_002333033.1 215919267 7065860 1762008..1762127 1 NC_002971.3 hypothetical protein 1762127 7065860 CBU_1831a Coxiella burnetii RSA 493 hypothetical protein YP_002333033.1 1762008 D 227377 CDS NP_820812.1 29655120 1209745 complement(1762674..1762811) 1 NC_002971.3 hypothetical protein 1762811 1209745 CBU_1833 Coxiella burnetii RSA 493 hypothetical protein NP_820812.1 1762674 R 227377 CDS NP_820813.1 29655121 1209746 1762841..1763755 1 NC_002971.3 glucose-1-phosphate thymidylyltransferase 1763755 rmlA 1209746 rmlA Coxiella burnetii RSA 493 glucose-1-phosphate thymidylyltransferase NP_820813.1 1762841 D 227377 CDS NP_820814.1 29655122 1209747 complement(1764101..1765480) 1 NC_002971.3 amine oxidase 1765480 1209747 CBU_1835 Coxiella burnetii RSA 493 amine oxidase NP_820814.1 1764101 R 227377 CDS NP_820815.1 29655123 1209748 complement(1765482..1766738) 1 NC_002971.3 homoserine dehydrogenase, NAD binding domain 1766738 1209748 CBU_1836 Coxiella burnetii RSA 493 homoserine dehydrogenase, NAD binding domain NP_820815.1 1765482 R 227377 CDS NP_820816.2 215919268 1209749 complement(1766752..1767792) 1 NC_002971.3 NAD-dependent epimerase/dehydratase 1767792 1209749 CBU_1837 Coxiella burnetii RSA 493 NAD-dependent epimerase/dehydratase NP_820816.2 1766752 R 227377 CDS NP_820817.1 29655125 1209750 complement(1767789..1768358) 1 NC_002971.3 dTDP-4-dehydrorhamnose 3,5-epimerase 1768358 rfbC 1209750 rfbC Coxiella burnetii RSA 493 dTDP-4-dehydrorhamnose 3,5-epimerase NP_820817.1 1767789 R 227377 CDS NP_820818.1 29655126 1209751 complement(1768368..1769594) 1 NC_002971.3 aminobutyraldehyde dehydrogenase 1769594 1209751 CBU_1839 Coxiella burnetii RSA 493 aminobutyraldehyde dehydrogenase NP_820818.1 1768368 R 227377 CDS NP_820819.1 29655127 1209752 1769744..1770478 1 NC_002971.3 'the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response'; 50S ribosomal protein L25 1770478 1209752 CBU_1840 Coxiella burnetii RSA 493 50S ribosomal protein L25 NP_820819.1 1769744 D 227377 CDS NP_820820.1 29655128 1209753 1770485..1771048 1 NC_002971.3 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1771048 pth 1209753 pth Coxiella burnetii RSA 493 peptidyl-tRNA hydrolase NP_820820.1 1770485 D 227377 CDS NP_820821.2 215919269 1209754 1771081..1772184 1 NC_002971.3 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1772184 1209754 CBU_1842 Coxiella burnetii RSA 493 GTP-dependent nucleic acid-binding protein EngD NP_820821.2 1771081 D 227377 CDS NP_820822.2 215919270 1209755 1772188..1772592 1 NC_002971.3 hypothetical protein 1772592 1209755 CBU_1843 Coxiella burnetii RSA 493 hypothetical protein NP_820822.2 1772188 D 227377 CDS YP_002333034.1 215919271 7065961 1772880..1773029 1 NC_002971.3 hypothetical protein 1773029 7065961 CBU_1843a Coxiella burnetii RSA 493 hypothetical protein YP_002333034.1 1772880 D 227377 CDS NP_820823.1 29655131 1209758 1773391..1774002 1 NC_002971.3 hypothetical protein 1774002 1209758 CBU_1845 Coxiella burnetii RSA 493 hypothetical protein NP_820823.1 1773391 D 227377 CDS NP_820825.1 29655133 1209760 complement(1774697..1774942) 1 NC_002971.3 hypothetical protein 1774942 1209760 CBU_1847 Coxiella burnetii RSA 493 hypothetical protein NP_820825.1 1774697 R 227377 CDS YP_002333035.1 215919272 7065984 1776549..1776911 1 NC_002971.3 hypothetical protein 1776911 7065984 CBU_1847b Coxiella burnetii RSA 493 hypothetical protein YP_002333035.1 1776549 D 227377 CDS NP_820826.1 29655134 1209762 complement(1777046..1777246) 1 NC_002971.3 hypothetical protein 1777246 1209762 CBU_1849 Coxiella burnetii RSA 493 hypothetical protein NP_820826.1 1777046 R 227377 CDS NP_820827.2 215919273 1209763 complement(1777464..1777949) 1 NC_002971.3 hypothetical protein 1777949 1209763 CBU_1850 Coxiella burnetii RSA 493 hypothetical protein NP_820827.2 1777464 R 227377 CDS NP_820828.2 215919274 1209764 1778164..1779960 1 NC_002971.3 hypothetical protein 1779960 1209764 CBU_1851 Coxiella burnetii RSA 493 hypothetical protein NP_820828.2 1778164 D 227377 CDS NP_820829.1 29655137 1209765 1779953..1781347 1 NC_002971.3 hypothetical protein 1781347 1209765 CBU_1852 Coxiella burnetii RSA 493 hypothetical protein NP_820829.1 1779953 D 227377 CDS NP_820830.1 29655138 1209766 complement(1781325..1781774) 1 NC_002971.3 GtrA family protein 1781774 1209766 CBU_1853 Coxiella burnetii RSA 493 GtrA family protein NP_820830.1 1781325 R 227377 CDS NP_820831.2 215919275 1209767 complement(1781857..1782165) 1 NC_002971.3 hypothetical protein 1782165 1209767 CBU_1854 Coxiella burnetii RSA 493 hypothetical protein NP_820831.2 1781857 R 227377 CDS NP_820832.2 215919276 1209768 complement(1782557..1782904) 1 NC_002971.3 fimbrial biogenesis domain-containing protein 1782904 pilF 1209768 pilF Coxiella burnetii RSA 493 fimbrial biogenesis domain-containing protein NP_820832.2 1782557 R 227377 CDS NP_820833.2 215919277 1209769 complement(1782931..1784070) 1 NC_002971.3 3-hydroxyisobutyryl-CoA hydrolase 1784070 1209769 CBU_1856 Coxiella burnetii RSA 493 3-hydroxyisobutyryl-CoA hydrolase NP_820833.2 1782931 R 227377 CDS NP_820834.1 29655142 1209770 complement(1784119..1785711) 1 NC_002971.3 oligopeptide transport ATP-binding protein 1785711 oppD 1209770 oppD Coxiella burnetii RSA 493 oligopeptide transport ATP-binding protein NP_820834.1 1784119 R 227377 CDS NP_820835.1 29655143 1209771 complement(1785829..1787226) 1 NC_002971.3 oligopeptide transport system permease 1787226 oppC 1209771 oppC Coxiella burnetii RSA 493 oligopeptide transport system permease NP_820835.1 1785829 R 227377 CDS NP_820836.2 215919278 1209772 complement(1787237..1788247) 1 NC_002971.3 oligopeptide ABC transporter permease 1788247 oppB 1209772 oppB Coxiella burnetii RSA 493 oligopeptide ABC transporter permease NP_820836.2 1787237 R 227377 CDS NP_820839.1 29655147 1209775 1790541..1791569 1 NC_002971.3 radical SAM domain-containing protein 1791569 1209775 CBU_1862 Coxiella burnetii RSA 493 radical SAM domain-containing protein NP_820839.1 1790541 D 227377 CDS NP_820840.1 29655148 1209776 complement(1791559..1793370) 1 NC_002971.3 hypothetical protein 1793370 1209776 CBU_1863 Coxiella burnetii RSA 493 hypothetical protein NP_820840.1 1791559 R 227377 CDS NP_820841.1 29655149 1209777 complement(1793634..1793729) 1 NC_002971.3 hypothetical protein 1793729 1209777 CBU_1864 Coxiella burnetii RSA 493 hypothetical protein NP_820841.1 1793634 R 227377 CDS NP_820842.2 215919279 1209778 complement(1793750..1794292) 1 NC_002971.3 hypothetical protein 1794292 1209778 CBU_1865 Coxiella burnetii RSA 493 hypothetical protein NP_820842.2 1793750 R 227377 CDS NP_820843.1 29655151 1209779 complement(1794295..1796556) 1 NC_002971.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1796556 parC 1209779 parC Coxiella burnetii RSA 493 DNA topoisomerase IV subunit A NP_820843.1 1794295 R 227377 CDS NP_820844.1 29655152 1209780 1796599..1796757 1 NC_002971.3 hypothetical protein 1796757 1209780 CBU_1867 Coxiella burnetii RSA 493 hypothetical protein NP_820844.1 1796599 D 227377 CDS YP_002333036.1 215919280 7065923 complement(1796901..1797044) 1 NC_002971.3 hypothetical protein 1797044 7065923 CBU_1867a Coxiella burnetii RSA 493 hypothetical protein YP_002333036.1 1796901 R 227377 CDS NP_820846.1 29655154 1209782 1797132..1797785 1 NC_002971.3 hypothetical protein 1797785 1209782 CBU_1869 Coxiella burnetii RSA 493 hypothetical protein NP_820846.1 1797132 D 227377 CDS NP_820847.1 29655155 1209783 1798072..1798719 1 NC_002971.3 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase 1798719 1209783 CBU_1870 Coxiella burnetii RSA 493 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase NP_820847.1 1798072 D 227377 CDS NP_820848.1 29655156 1209784 complement(1798669..1799274) 1 NC_002971.3 para-aminobenzoate synthase glutamine amidotransferase component II; anthranilate synthase component II 1799274 pabA 1209784 pabA Coxiella burnetii RSA 493 anthranilate synthase component II NP_820848.1 1798669 R 227377 CDS NP_820849.2 215919281 1209785 complement(1799255..1799950) 1 NC_002971.3 ribulose-phosphate 3-epimerase 1799950 rpe 1209785 rpe Coxiella burnetii RSA 493 ribulose-phosphate 3-epimerase NP_820849.2 1799255 R 227377 CDS NP_820850.1 29655158 1209786 complement(1799950..1800765) 1 NC_002971.3 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 1800765 djlA 1209786 djlA Coxiella burnetii RSA 493 Dna-J like membrane chaperone protein NP_820850.1 1799950 R 227377 CDS NP_820851.1 29655159 1209787 1800801..1802108 1 NC_002971.3 glutamate--cysteine ligase 1802108 1209787 CBU_1874 Coxiella burnetii RSA 493 glutamate--cysteine ligase NP_820851.1 1800801 D 227377 CDS NP_820852.1 29655160 1209788 1802162..1803127 1 NC_002971.3 'catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione'; glutathione synthetase 1803127 gshB 1209788 gshB Coxiella burnetii RSA 493 glutathione synthetase NP_820852.1 1802162 D 227377 CDS NP_820853.1 29655161 1209789 1803534..1804298 1 NC_002971.3 SAM-dependent methyltransferase 1804298 1209789 CBU_1876 Coxiella burnetii RSA 493 SAM-dependent methyltransferase NP_820853.1 1803534 D 227377 CDS NP_820854.1 29655162 1209790 complement(1804281..1805564) 1 NC_002971.3 ATPase 1805564 1209790 CBU_1877 Coxiella burnetii RSA 493 ATPase NP_820854.1 1804281 R 227377 CDS NP_820855.1 29655163 1209791 complement(1805709..1806128) 1 NC_002971.3 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1806128 1209791 CBU_1878 Coxiella burnetii RSA 493 iron-sulfur cluster insertion protein ErpA NP_820855.1 1805709 R 227377 CDS NP_820856.1 29655164 1209792 1806224..1806853 1 NC_002971.3 peptide deformylase 1806853 1209792 CBU_1879 Coxiella burnetii RSA 493 peptide deformylase NP_820856.1 1806224 D 227377 CDS NP_820857.1 29655165 1209793 1806850..1807269 1 NC_002971.3 hypothetical protein 1807269 1209793 CBU_1880 Coxiella burnetii RSA 493 hypothetical protein NP_820857.1 1806850 D 227377 CDS NP_820858.1 29655166 1209794 complement(1807266..1807439) 1 NC_002971.3 rubredoxin 1807439 1209794 CBU_1881 Coxiella burnetii RSA 493 rubredoxin NP_820858.1 1807266 R 227377 CDS NP_820859.1 29655167 1209795 1807482..1808789 1 NC_002971.3 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1808789 hemL 1209795 hemL Coxiella burnetii RSA 493 glutamate-1-semialdehyde aminotransferase NP_820859.1 1807482 D 227377 CDS NP_820860.1 29655168 1209796 1808786..1809340 1 NC_002971.3 queuosine biosynthesis protein 1809340 queD 1209796 queD Coxiella burnetii RSA 493 queuosine biosynthesis protein NP_820860.1 1808786 D 227377 CDS NP_820861.1 29655169 1209797 1809343..1809822 1 NC_002971.3 hypothetical protein 1809822 1209797 CBU_1884 Coxiella burnetii RSA 493 hypothetical protein NP_820861.1 1809343 D 227377 CDS NP_820863.1 29655171 1209799 complement(1810057..1810197) 1 NC_002971.3 hypothetical protein 1810197 1209799 CBU_1886 Coxiella burnetii RSA 493 hypothetical protein NP_820863.1 1810057 R 227377 CDS NP_820864.1 29655172 1209800 complement(1810207..1812588) 1 NC_002971.3 multimodular transpeptidase-transglycosylase PBP 1A 1812588 ponA 1209800 ponA Coxiella burnetii RSA 493 multimodular transpeptidase-transglycosylase PBP 1A NP_820864.1 1810207 R 227377 CDS NP_820865.1 29655173 1209801 1812658..1813452 1 NC_002971.3 hypothetical protein 1813452 1209801 CBU_1888 Coxiella burnetii RSA 493 hypothetical protein NP_820865.1 1812658 D 227377 CDS NP_820867.1 29655175 1209803 1814037..1814345 1 NC_002971.3 hypothetical protein 1814345 1209803 CBU_1890 Coxiella burnetii RSA 493 hypothetical protein NP_820867.1 1814037 D 227377 CDS NP_820868.2 215919282 1209804 1814326..1815387 1 NC_002971.3 type II and III secretion system family protein 1815387 pilQ 1209804 pilQ Coxiella burnetii RSA 493 type II and III secretion system family protein NP_820868.2 1814326 D 227377 CDS NP_820869.1 29655177 1209805 1815320..1815859 1 NC_002971.3 shikimate kinase 1815859 aroK 1209805 aroK Coxiella burnetii RSA 493 shikimate kinase NP_820869.1 1815320 D 227377 CDS NP_820870.1 29655178 1209806 1815856..1816938 1 NC_002971.3 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1816938 aroB 1209806 aroB Coxiella burnetii RSA 493 3-dehydroquinate synthase NP_820870.1 1815856 D 227377 CDS NP_820871.1 29655179 1209807 complement(1817017..1817202) 1 NC_002971.3 hypothetical protein 1817202 1209807 CBU_1894 Coxiella burnetii RSA 493 hypothetical protein NP_820871.1 1817017 R 227377 CDS YP_002333037.1 215919283 7065929 complement(1817225..1817380) 1 NC_002971.3 hypothetical protein 1817380 7065929 CBU_1894a Coxiella burnetii RSA 493 hypothetical protein YP_002333037.1 1817225 R 227377 CDS NP_820872.1 29655180 1209808 1817446..1817712 1 NC_002971.3 hypothetical protein 1817712 1209808 CBU_1895 Coxiella burnetii RSA 493 hypothetical protein NP_820872.1 1817446 D 227377 CDS NP_820873.2 215919284 1209809 complement(1817721..1818959) 1 NC_002971.3 major facilitator family transporter 1818959 1209809 CBU_1896 Coxiella burnetii RSA 493 major facilitator family transporter NP_820873.2 1817721 R 227377 CDS YP_002333038.1 215919285 1209811 1819165..1820259 1 NC_002971.3 transposase 1820259 1209811 CBU_1896a Coxiella burnetii RSA 493 transposase YP_002333038.1 1819165 D 227377 CDS YP_002333039.1 215919286 7065962 complement(1820256..1820528) 1 NC_002971.3 hypothetical protein 1820528 7065962 CBU_1896b Coxiella burnetii RSA 493 hypothetical protein YP_002333039.1 1820256 R 227377 CDS NP_820876.1 29655184 1209812 complement(1820580..1821161) 1 NC_002971.3 methyltransferase 1821161 1209812 CBU_1899 Coxiella burnetii RSA 493 methyltransferase NP_820876.1 1820580 R 227377 CDS NP_820878.1 29655186 1209814 complement(1821657..1822988) 1 NC_002971.3 M16 family peptidase 1822988 1209814 CBU_1901 Coxiella burnetii RSA 493 M16 family peptidase NP_820878.1 1821657 R 227377 CDS NP_820879.1 29655187 1209815 complement(1822988..1824367) 1 NC_002971.3 M16 family peptidase 1824367 1209815 CBU_1902 Coxiella burnetii RSA 493 M16 family peptidase NP_820879.1 1822988 R 227377 CDS NP_820880.1 29655188 1209816 1824556..1825530 1 NC_002971.3 cell division protein 1825530 ftsY 1209816 ftsY Coxiella burnetii RSA 493 cell division protein NP_820880.1 1824556 D 227377 CDS NP_820881.1 29655189 1209817 1825537..1826190 1 NC_002971.3 cell division ATP-binding protein 1826190 ftsE 1209817 ftsE Coxiella burnetii RSA 493 cell division ATP-binding protein NP_820881.1 1825537 D 227377 CDS NP_820882.2 215919287 1209818 1826187..1827128 1 NC_002971.3 ABC transporter permease 1827128 ftsX 1209818 ftsX Coxiella burnetii RSA 493 ABC transporter permease NP_820882.2 1826187 D 227377 CDS NP_820883.1 29655191 1209819 1827170..1827319 1 NC_002971.3 hypothetical protein 1827319 1209819 CBU_1906 Coxiella burnetii RSA 493 hypothetical protein NP_820883.1 1827170 D 227377 CDS NP_820884.1 29655192 1209820 complement(1827607..1828323) 1 NC_002971.3 acetyltransferase 1828323 1209820 CBU_1907 Coxiella burnetii RSA 493 acetyltransferase NP_820884.1 1827607 R 227377 CDS NP_820885.1 29655193 1209821 complement(1828354..1828452) 1 NC_002971.3 hypothetical protein 1828452 1209821 CBU_1908 Coxiella burnetii RSA 493 hypothetical protein NP_820885.1 1828354 R 227377 CDS NP_820886.1 29655194 1209822 1828489..1829355 1 NC_002971.3 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1829355 rpoH 1209822 rpoH Coxiella burnetii RSA 493 RNA polymerase factor sigma-32 NP_820886.1 1828489 D 227377 CDS NP_820887.1 29655195 1209823 1829381..1830139 1 NC_002971.3 hypothetical protein 1830139 com1 1209823 com1 Coxiella burnetii RSA 493 hypothetical protein NP_820887.1 1829381 D 227377 CDS NP_820888.1 29655196 1209824 complement(1830313..1830432) 1 NC_002971.3 hypothetical protein 1830432 1209824 CBU_1911 Coxiella burnetii RSA 493 hypothetical protein NP_820888.1 1830313 R 227377 CDS NP_820890.1 29655198 1209826 1830769..1831728 1 NC_002971.3 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1831728 glyQ 1209826 glyQ Coxiella burnetii RSA 493 glycyl-tRNA synthetase subunit alpha NP_820890.1 1830769 D 227377 CDS NP_820891.2 215919288 1209827 1831722..1833800 1 NC_002971.3 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1833800 glyS 1209827 glyS Coxiella burnetii RSA 493 glycyl-tRNA synthetase subunit beta NP_820891.2 1831722 D 227377 CDS NP_820892.1 29655200 1209828 1833797..1835089 1 NC_002971.3 ribosomal RNA small subunit methyltransferase B 1835089 sun 1209828 sun Coxiella burnetii RSA 493 ribosomal RNA small subunit methyltransferase B NP_820892.1 1833797 D 227377 CDS NP_820893.1 29655201 1209829 complement(1835076..1835516) 1 NC_002971.3 universal stress protein family protein 1835516 1209829 CBU_1916 Coxiella burnetii RSA 493 universal stress protein family protein NP_820893.1 1835076 R 227377 CDS NP_820894.1 29655202 1209830 1836042..1836176 1 NC_002971.3 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1836176 rpmH 1209830 rpmH Coxiella burnetii RSA 493 50S ribosomal protein L34 NP_820894.1 1836042 D 227377 CDS NP_820895.2 215919289 1209831 1836173..1836541 1 NC_002971.3 ribonuclease P protein component 1836541 rnpA 1209831 rnpA Coxiella burnetii RSA 493 ribonuclease P protein component NP_820895.2 1836173 D 227377 CDS NP_820896.2 215919290 1209832 1836577..1836747 1 NC_002971.3 hypothetical protein 1836747 1209832 CBU_1919 Coxiella burnetii RSA 493 hypothetical protein NP_820896.2 1836577 D 227377 CDS NP_820897.1 29655205 1209833 1836751..1838451 1 NC_002971.3 inner membrane protein oxaA 1838451 yidC 1209833 yidC Coxiella burnetii RSA 493 inner membrane protein oxaA NP_820897.1 1836751 D 227377 CDS NP_820898.1 29655206 1209834 1838596..1838697 1 NC_002971.3 hypothetical protein 1838697 1209834 CBU_1921 Coxiella burnetii RSA 493 hypothetical protein NP_820898.1 1838596 D 227377 CDS NP_820899.1 29655207 1209835 1838882..1840303 1 NC_002971.3 'in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE'; tRNA modification GTPase TrmE 1840303 trmE 1209835 trmE Coxiella burnetii RSA 493 tRNA modification GTPase TrmE NP_820899.1 1838882 D 227377 CDS NP_820901.2 161511216 1209837 1840616..1842499 1 NC_002971.3 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1842499 gidA 1209837 gidA Coxiella burnetii RSA 493 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA NP_820901.2 1840616 D 227377 CDS NP_820902.1 29655210 1209838 1842531..1843145 1 NC_002971.3 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1843145 gidB 1209838 gidB Coxiella burnetii RSA 493 16S rRNA methyltransferase GidB NP_820902.1 1842531 D 227377 CDS NP_820903.1 29655211 1209839 1843152..1843922 1 NC_002971.3 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein 1843922 soj 1209839 soj Coxiella burnetii RSA 493 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein NP_820903.1 1843152 D 227377 CDS NP_820904.2 215919291 1209840 1843913..1844785 1 NC_002971.3 chromosome partitioning protein 1844785 parB 1209840 parB Coxiella burnetii RSA 493 chromosome partitioning protein NP_820904.2 1843913 D 227377 CDS NP_820905.2 215919292 1209841 1844795..1847605 1 NC_002971.3 acyl-CoA synthetase 1847605 1209841 CBU_1928 Coxiella burnetii RSA 493 acyl-CoA synthetase NP_820905.2 1844795 D 227377 CDS NP_820906.2 215919293 1209842 1847592..1848986 1 NC_002971.3 major facilitator transporter 1848986 1209842 CBU_1929 Coxiella burnetii RSA 493 major facilitator transporter NP_820906.2 1847592 D 227377 CDS NP_820907.1 29655215 1209843 1849038..1849220 1 NC_002971.3 hypothetical protein 1849220 1209843 CBU_1930 Coxiella burnetii RSA 493 hypothetical protein NP_820907.1 1849038 D 227377 CDS YP_002333040.1 215919294 7065907 1849302..1849592 1 NC_002971.3 hypothetical protein 1849592 7065907 CBU_1930a Coxiella burnetii RSA 493 hypothetical protein YP_002333040.1 1849302 D 227377 CDS NP_820908.1 29655216 1209844 1849612..1849743 1 NC_002971.3 hypothetical protein 1849743 1209844 CBU_1931 Coxiella burnetii RSA 493 hypothetical protein NP_820908.1 1849612 D 227377 CDS NP_820909.2 215919295 1209845 complement(1849745..1849945) 1 NC_002971.3 hypothetical protein 1849945 1209845 CBU_1932 Coxiella burnetii RSA 493 hypothetical protein NP_820909.2 1849745 R 227377 CDS NP_820910.2 215919296 1209846 1850017..1850871 1 NC_002971.3 Ku protein 1850871 1209846 CBU_1933 Coxiella burnetii RSA 493 Ku protein NP_820910.2 1850017 D 227377 CDS NP_820911.2 215919297 1209847 1850868..1853315 1 NC_002971.3 DNA ligase D 1853315 1209847 CBU_1934 Coxiella burnetii RSA 493 DNA ligase D NP_820911.2 1850868 D 227377 CDS YP_002333041.1 215919298 7065880 1853378..1853485 1 NC_002971.3 hypothetical protein 1853485 7065880 CBU_1934a Coxiella burnetii RSA 493 hypothetical protein YP_002333041.1 1853378 D 227377 CDS NP_820913.1 29655221 1209849 complement(1854191..1854988) 1 NC_002971.3 hypothetical protein 1854988 1209849 CBU_1936 Coxiella burnetii RSA 493 hypothetical protein NP_820913.1 1854191 R 227377 CDS NP_820914.2 215919299 1209851 1856529..1857014 1 NC_002971.3 ATP synthase F0 subunit I 1857014 atpI 1209851 atpI Coxiella burnetii RSA 493 ATP synthase F0 subunit I NP_820914.2 1856529 D 227377 CDS NP_820915.1 29655223 1209852 1857015..1857809 1 NC_002971.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 1857809 atpB 1209852 atpB Coxiella burnetii RSA 493 ATP synthase F0F1 subunit A NP_820915.1 1857015 D 227377 CDS NP_820916.1 29655224 1209853 1857827..1858129 1 NC_002971.3 ATP synthase subunit C 1858129 atpE 1209853 atpE Coxiella burnetii RSA 493 ATP synthase subunit C NP_820916.1 1857827 D 227377 CDS NP_820917.1 29655225 1209854 1858258..1858728 1 NC_002971.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 1858728 atpF 1209854 atpF Coxiella burnetii RSA 493 ATP synthase F0F1 subunit B NP_820917.1 1858258 D 227377 CDS NP_820918.1 29655226 1209855 1858728..1859285 1 NC_002971.3 ATP synthase subunit delta 1859285 atpH 1209855 atpH Coxiella burnetii RSA 493 ATP synthase subunit delta NP_820918.1 1858728 D 227377 CDS NP_820919.1 29655227 1209856 1859293..1860840 1 NC_002971.3 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1860840 atpA 1209856 atpA Coxiella burnetii RSA 493 ATP synthase F0F1 subunit alpha NP_820919.1 1859293 D 227377 CDS NP_820920.1 29655228 1209857 1860939..1861808 1 NC_002971.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1861808 atpG 1209857 atpG Coxiella burnetii RSA 493 ATP synthase F0F1 subunit gamma NP_820920.1 1860939 D 227377 CDS NP_820921.2 215919300 1209858 1861844..1863295 1 NC_002971.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1863295 atpD 1209858 atpD Coxiella burnetii RSA 493 ATP synthase F0F1 subunit beta NP_820921.2 1861844 D 227377 CDS NP_820922.1 29655230 1209859 1863419..1863847 1 NC_002971.3 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 1863847 atpC 1209859 atpC Coxiella burnetii RSA 493 ATP synthase F0F1 subunit epsilon NP_820922.1 1863419 D 227377 CDS NP_820923.1 29655231 1209860 1863866..1865233 1 NC_002971.3 glucosamine-1-phosphate acetyltransferase; UDP-N-acetylglucosamine pyrophosphorylase 1865233 glmU 1209860 glmU Coxiella burnetii RSA 493 UDP-N-acetylglucosamine pyrophosphorylase NP_820923.1 1863866 D 227377 CDS YP_002333042.1 215919301 7065952 1865500..1865685 1 NC_002971.3 hypothetical protein 1865685 7065952 CBU_1947a Coxiella burnetii RSA 493 hypothetical protein YP_002333042.1 1865500 D 227377 CDS NP_820924.1 29655232 1209861 1865705..1865881 1 NC_002971.3 hypothetical protein 1865881 1209861 CBU_1948 Coxiella burnetii RSA 493 hypothetical protein NP_820924.1 1865705 D 227377 CDS NP_820925.1 29655233 1209863 complement(1867254..1867700) 1 NC_002971.3 hypothetical protein 1867700 1209863 CBU_1950 Coxiella burnetii RSA 493 hypothetical protein NP_820925.1 1867254 R 227377 CDS NP_820926.1 29655234 1209864 1867762..1867878 1 NC_002971.3 hypothetical protein 1867878 1209864 CBU_1951 Coxiella burnetii RSA 493 hypothetical protein NP_820926.1 1867762 D 227377 CDS NP_820927.1 29655235 1209865 1867944..1869542 1 NC_002971.3 ABC transporter ATP-binding protein 1869542 1209865 CBU_1952 Coxiella burnetii RSA 493 ABC transporter ATP-binding protein NP_820927.1 1867944 D 227377 CDS NP_820928.1 29655236 1209866 complement(1869500..1870069) 1 NC_002971.3 hypothetical protein 1870069 1209866 CBU_1953 Coxiella burnetii RSA 493 hypothetical protein NP_820928.1 1869500 R 227377 CDS NP_820929.1 29655237 1209867 complement(1870307..1871179) 1 NC_002971.3 (2R)-phospho-3-sulfolactate synthase 1871179 1209867 CBU_1954 Coxiella burnetii RSA 493 (2R)-phospho-3-sulfolactate synthase NP_820929.1 1870307 R 227377 CDS NP_820930.2 215919302 1209868 1871168..1872427 1 NC_002971.3 NAD(P) transhydrogenase subunit alpha 1872427 pntAA 1209868 pntAA Coxiella burnetii RSA 493 NAD(P) transhydrogenase subunit alpha NP_820930.2 1871168 D 227377 CDS NP_820931.1 29655239 1209869 1872810..1873109 1 NC_002971.3 NAD(P) transhydrogenase subunit alpha 1873109 pntAB 1209869 pntAB Coxiella burnetii RSA 493 NAD(P) transhydrogenase subunit alpha NP_820931.1 1872810 D 227377 CDS NP_820932.1 29655240 1209870 1873106..1874476 1 NC_002971.3 NAD(P) transhydrogenase subunit alpha 1874476 pntB 1209870 pntB Coxiella burnetii RSA 493 NAD(P) transhydrogenase subunit alpha NP_820932.1 1873106 D 227377 CDS NP_820935.2 215919303 1209873 complement(1875136..1875918) 1 NC_002971.3 'in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase'; 16S ribosomal RNA methyltransferase RsmE 1875918 1209873 CBU_1960 Coxiella burnetii RSA 493 16S ribosomal RNA methyltransferase RsmE NP_820935.2 1875136 R 227377 CDS YP_002333043.1 215919304 7065914 1875965..1876237 1 NC_002971.3 hypothetical protein 1876237 7065914 CBU_1959a Coxiella burnetii RSA 493 hypothetical protein YP_002333043.1 1875965 D 227377 CDS YP_002333044.1 215919305 1209874 complement(1876234..1877328) 1 NC_002971.3 transposase 1877328 1209874 CBU_1959b Coxiella burnetii RSA 493 transposase YP_002333044.1 1876234 R 227377 CDS NP_820939.1 29655247 1209877 complement(1879505..1880338) 1 NC_002971.3 peptide release factor-glutamine N5-methyltransferase 1880338 hemK 1209877 hemK Coxiella burnetii RSA 493 peptide release factor-glutamine N5-methyltransferase NP_820939.1 1879505 R 227377 CDS NP_820940.1 29655248 1209878 complement(1880341..1881426) 1 NC_002971.3 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1881426 prfA 1209878 prfA Coxiella burnetii RSA 493 peptide chain release factor 1 NP_820940.1 1880341 R 227377 CDS NP_820941.1 29655249 1209879 complement(1881423..1882664) 1 NC_002971.3 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1882664 hemA 1209879 hemA Coxiella burnetii RSA 493 glutamyl-tRNA reductase NP_820941.1 1881423 R 227377 CDS NP_820942.1 29655250 1209880 1882741..1883970 1 NC_002971.3 Bcr/CflA subfamily drug resistance transporter 1883970 1209880 CBU_1967 Coxiella burnetii RSA 493 Bcr/CflA subfamily drug resistance transporter NP_820942.1 1882741 D 227377 CDS NP_820943.2 215919306 1209881 complement(1883948..1884250) 1 NC_002971.3 dihydroneopterin aldolase 1884250 folB 1209881 folB Coxiella burnetii RSA 493 dihydroneopterin aldolase NP_820943.2 1883948 R 227377 CDS NP_820944.1 29655252 1209882 complement(1884294..1884737) 1 NC_002971.3 RNA polymerase-binding protein DksA 1884737 dksA 1209882 dksA Coxiella burnetii RSA 493 RNA polymerase-binding protein DksA NP_820944.1 1884294 R 227377 CDS NP_820945.1 29655253 1209883 complement(1884879..1885709) 1 NC_002971.3 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1885709 dapF 1209883 dapF Coxiella burnetii RSA 493 diaminopimelate epimerase NP_820945.1 1884879 R 227377 CDS NP_820946.1 29655254 1209884 complement(1885699..1885857) 1 NC_002971.3 hypothetical protein 1885857 1209884 CBU_1971 Coxiella burnetii RSA 493 hypothetical protein NP_820946.1 1885699 R 227377 CDS NP_820947.1 29655255 1209885 complement(1886058..1886279) 1 NC_002971.3 LuxR family transcriptional regulator 1886279 1209885 CBU_1972 Coxiella burnetii RSA 493 LuxR family transcriptional regulator NP_820947.1 1886058 R 227377 CDS NP_820948.1 29655256 1209886 complement(1886294..1886449) 1 NC_002971.3 hypothetical protein 1886449 1209886 CBU_1973 Coxiella burnetii RSA 493 hypothetical protein NP_820948.1 1886294 R 227377 CDS NP_820949.1 29655257 1209887 1886459..1886554 1 NC_002971.3 hypothetical protein 1886554 1209887 CBU_1974 Coxiella burnetii RSA 493 hypothetical protein NP_820949.1 1886459 D 227377 CDS NP_820950.2 215919307 1209888 1886551..1887261 1 NC_002971.3 phospholipase/carboxylesterase 1887261 1209888 CBU_1975 Coxiella burnetii RSA 493 phospholipase/carboxylesterase NP_820950.2 1886551 D 227377 CDS NP_820951.1 29655259 1209889 complement(1887241..1887900) 1 NC_002971.3 nucleotidyl transferase 1887900 1209889 CBU_1976 Coxiella burnetii RSA 493 nucleotidyl transferase NP_820951.1 1887241 R 227377 CDS NP_820952.2 215919308 1209890 complement(1887906..1889003) 1 NC_002971.3 phosphotransferase enzyme family protein 1889003 1209890 CBU_1977 Coxiella burnetii RSA 493 phosphotransferase enzyme family protein NP_820952.2 1887906 R 227377 CDS NP_820953.1 29655261 1209891 1888985..1891597 1 NC_002971.3 organic solvent tolerance protein 1891597 ostA 1209891 ostA Coxiella burnetii RSA 493 organic solvent tolerance protein NP_820953.1 1888985 D 227377 CDS NP_820955.2 215919309 1209893 1891603..1892568 1 NC_002971.3 peptidyl-prolyl cis-trans isomerase surA 1892568 1209893 CBU_1980 Coxiella burnetii RSA 493 peptidyl-prolyl cis-trans isomerase surA NP_820955.2 1891603 D 227377 CDS NP_820956.1 29655264 1209894 1892568..1893491 1 NC_002971.3 4-hydroxythreonine-4-phosphate dehydrogenase 1893491 pdxA 1209894 pdxA Coxiella burnetii RSA 493 4-hydroxythreonine-4-phosphate dehydrogenase NP_820956.1 1892568 D 227377 CDS NP_820957.2 215919310 1209895 1893643..1894419 1 NC_002971.3 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1894419 ksgA 1209895 ksgA Coxiella burnetii RSA 493 dimethyladenosine transferase NP_820957.2 1893643 D 227377 CDS NP_820958.1 29655266 1209896 1894532..1894966 1 NC_002971.3 universal stress protein family protein 1894966 uspA 1209896 uspA Coxiella burnetii RSA 493 universal stress protein family protein NP_820958.1 1894532 D 227377 CDS NP_820959.1 29655267 1209897 1895135..1895509 1 NC_002971.3 hypothetical protein 1895509 1209897 CBU_1984 Coxiella burnetii RSA 493 hypothetical protein NP_820959.1 1895135 D 227377 CDS NP_820960.1 29655268 1209898 1895554..1896252 1 NC_002971.3 hypothetical protein 1896252 1209898 CBU_1985 Coxiella burnetii RSA 493 hypothetical protein NP_820960.1 1895554 D 227377 CDS NP_820961.1 29655269 1209899 1896316..1897257 1 NC_002971.3 U7 family peptidase 1897257 sppA 1209899 sppA Coxiella burnetii RSA 493 U7 family peptidase NP_820961.1 1896316 D 227377 CDS NP_820962.1 29655270 1209900 1897270..1898145 1 NC_002971.3 'hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP'; diadenosine tetraphosphatase 1898145 apaH 1209900 apaH Coxiella burnetii RSA 493 diadenosine tetraphosphatase NP_820962.1 1897270 D 227377 CDS YP_002333045.1 215919311 7065909 1898294..1898428 1 NC_002971.3 hypothetical protein 1898428 7065909 CBU_1987a Coxiella burnetii RSA 493 hypothetical protein YP_002333045.1 1898294 D 227377 CDS YP_002333046.1 215919312 1209903 1898514..1899608 1 NC_002971.3 transposase 1899608 1209903 CBU_1987b Coxiella burnetii RSA 493 transposase YP_002333046.1 1898514 D 227377 CDS YP_002333047.1 215919313 7065872 complement(1899605..1899877) 1 NC_002971.3 hypothetical protein 1899877 7065872 CBU_1987c Coxiella burnetii RSA 493 hypothetical protein YP_002333047.1 1899605 R 227377 CDS NP_820966.1 29655274 1209904 1900067..1900321 1 NC_002971.3 RelB 1900321 relB 1209904 relB Coxiella burnetii RSA 493 RelB NP_820966.1 1900067 D 227377 CDS NP_820967.1 29655275 1209905 1900321..1900596 1 NC_002971.3 RelE 1900596 relE 1209905 relE Coxiella burnetii RSA 493 RelE NP_820967.1 1900321 D 227377 CDS NP_820968.1 29655276 1209906 complement(1900569..1901054) 1 NC_002971.3 dihydrofolate reductase 1901054 folA 1209906 folA Coxiella burnetii RSA 493 dihydrofolate reductase NP_820968.1 1900569 R 227377 CDS NP_820969.2 215919314 1209907 complement(1901051..1901854) 1 NC_002971.3 hypothetical protein 1901854 1209907 CBU_1994 Coxiella burnetii RSA 493 hypothetical protein NP_820969.2 1901051 R 227377 CDS NP_820970.2 215919315 1209908 1902050..1902337 1 NC_002971.3 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1902337 1209908 CBU_1995 Coxiella burnetii RSA 493 acylphosphatase NP_820970.2 1902050 D 227377 CDS NP_820971.1 29655279 1209909 complement(1902313..1902867) 1 NC_002971.3 'Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate'; D,D-heptose 1,7-bisphosphate phosphatase 1902867 1209909 CBU_1996 Coxiella burnetii RSA 493 D,D-heptose 1,7-bisphosphate phosphatase NP_820971.1 1902313 R 227377 CDS NP_820972.1 29655280 1209910 complement(1902880..1903824) 1 NC_002971.3 methionyl-tRNA formyltransferase 1903824 fmt 1209910 fmt Coxiella burnetii RSA 493 methionyl-tRNA formyltransferase NP_820972.1 1902880 R 227377 CDS NP_820973.1 29655281 1209911 1904012..1904938 1 NC_002971.3 DNA protecting protein DprA 1904938 1209911 CBU_1998 Coxiella burnetii RSA 493 DNA protecting protein DprA NP_820973.1 1904012 D 227377 CDS NP_820974.2 215919316 1209912 1904935..1905414 1 NC_002971.3 Smg protein 1905414 smg 1209912 smg Coxiella burnetii RSA 493 Smg protein NP_820974.2 1904935 D 227377 CDS NP_820975.1 29655283 1209913 1905417..1907714 1 NC_002971.3 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 1907714 topA 1209913 topA Coxiella burnetii RSA 493 DNA topoisomerase I NP_820975.1 1905417 D 227377 CDS NP_820976.1 29655284 1209914 complement(1907721..1907891) 1 NC_002971.3 hypothetical protein 1907891 1209914 CBU_2001 Coxiella burnetii RSA 493 hypothetical protein NP_820976.1 1907721 R 227377 CDS NP_820977.1 29655285 1209915 1907922..1908422 1 NC_002971.3 phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit 1908422 purE 1209915 purE Coxiella burnetii RSA 493 phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit NP_820977.1 1907922 D 227377 CDS NP_820978.1 29655286 1209916 1908425..1908985 1 NC_002971.3 sua5/YciO/YrdC/YwlC family protein 1908985 1209916 CBU_2003 Coxiella burnetii RSA 493 sua5/YciO/YrdC/YwlC family protein NP_820978.1 1908425 D 227377 CDS YP_002333048.1 215919317 7065975 1909428..1909568 1 NC_002971.3 hypothetical protein 1909568 7065975 CBU_2003a Coxiella burnetii RSA 493 hypothetical protein YP_002333048.1 1909428 D 227377 CDS NP_820979.1 29655287 1209917 complement(1909646..1910701) 1 NC_002971.3 heptosyl transferase glycosyltransferase 9 protein 1910701 1209917 CBU_2004 Coxiella burnetii RSA 493 heptosyl transferase glycosyltransferase 9 protein NP_820979.1 1909646 R 227377 CDS NP_820980.1 29655288 1209918 complement(1910709..1911986) 1 NC_002971.3 signal transduction histidine kinase-like protein 1911986 rstB 1209918 rstB Coxiella burnetii RSA 493 signal transduction histidine kinase-like protein NP_820980.1 1910709 R 227377 CDS NP_820981.1 29655289 1209919 complement(1911983..1912720) 1 NC_002971.3 transcriptional regulatory protein 1912720 1209919 CBU_2006 Coxiella burnetii RSA 493 transcriptional regulatory protein NP_820981.1 1911983 R 227377 CDS NP_820982.1 29655290 1209920 complement(1912769..1913956) 1 NC_002971.3 hypothetical protein 1913956 1209920 CBU_2007 Coxiella burnetii RSA 493 hypothetical protein NP_820982.1 1912769 R 227377 CDS NP_820983.1 29655291 1209921 1914102..1915880 1 NC_002971.3 'catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase'; arginyl-tRNA synthetase 1915880 argS 1209921 argS Coxiella burnetii RSA 493 arginyl-tRNA synthetase NP_820983.1 1914102 D 227377 CDS NP_820984.2 215919318 1209922 1915877..1917211 1 NC_002971.3 hypothetical protein 1917211 1209922 CBU_2009 Coxiella burnetii RSA 493 hypothetical protein NP_820984.2 1915877 D 227377 CDS NP_820985.1 29655293 1209923 1917208..1917522 1 NC_002971.3 hypothetical protein 1917522 1209923 CBU_2010 Coxiella burnetii RSA 493 hypothetical protein NP_820985.1 1917208 D 227377 CDS NP_820986.2 215919319 1209924 1917713..1918327 1 NC_002971.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1918327 hslV 1209924 hslV Coxiella burnetii RSA 493 ATP-dependent protease peptidase subunit NP_820986.2 1917713 D 227377 CDS NP_820987.2 215919320 1209925 1918352..1919749 1 NC_002971.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1919749 hslU 1209925 hslU Coxiella burnetii RSA 493 ATP-dependent protease ATP-binding subunit HslU NP_820987.2 1918352 D 227377 CDS NP_820988.1 29655296 1209926 complement(1919703..1920800) 1 NC_002971.3 hypothetical protein 1920800 1209926 CBU_2013 Coxiella burnetii RSA 493 hypothetical protein NP_820988.1 1919703 R 227377 CDS NP_820989.1 29655297 1209927 1921123..1921506 1 NC_002971.3 hypothetical protein 1921506 1209927 CBU_2014 Coxiella burnetii RSA 493 hypothetical protein NP_820989.1 1921123 D 227377 CDS NP_820990.2 215919321 1209929 1923186..1923782 1 NC_002971.3 hypothetical protein 1923782 1209929 CBU_2016 Coxiella burnetii RSA 493 hypothetical protein NP_820990.2 1923186 D 227377 CDS NP_820991.1 29655299 1209930 1923862..1924614 1 NC_002971.3 ubiquinone/menaquinone biosynthesis methyltransferase ubiE 1924614 ubiE 1209930 ubiE Coxiella burnetii RSA 493 ubiquinone/menaquinone biosynthesis methyltransferase ubiE NP_820991.1 1923862 D 227377 CDS NP_820992.2 215919322 1209931 1924614..1925228 1 NC_002971.3 hypothetical protein 1925228 1209931 CBU_2018 Coxiella burnetii RSA 493 hypothetical protein NP_820992.2 1924614 D 227377 CDS NP_820993.1 29655301 1209932 1925225..1926850 1 NC_002971.3 2-polyprenylphenol 6-hydroxylase 1926850 ubiB 1209932 ubiB Coxiella burnetii RSA 493 2-polyprenylphenol 6-hydroxylase NP_820993.1 1925225 D 227377 CDS NP_820994.1 29655302 1209933 complement(1927255..1928685) 1 NC_002971.3 glutamate/gamma-aminobutyrate antiporter 1928685 1209933 CBU_2020 Coxiella burnetii RSA 493 glutamate/gamma-aminobutyrate antiporter NP_820994.1 1927255 R 227377 CDS NP_820995.2 215919323 1209934 complement(1928747..1930042) 1 NC_002971.3 ATPase 1930042 1209934 CBU_2021 Coxiella burnetii RSA 493 ATPase NP_820995.2 1928747 R 227377 CDS NP_820996.1 29655304 1209936 complement(1931517..1931762) 1 NC_002971.3 hypothetical protein 1931762 1209936 CBU_2023 Coxiella burnetii RSA 493 hypothetical protein NP_820996.1 1931517 R 227377 CDS NP_820997.1 29655305 1209937 1931840..1932790 1 NC_002971.3 cystathionine beta-synthase 1932790 1209937 CBU_2024 Coxiella burnetii RSA 493 cystathionine beta-synthase NP_820997.1 1931840 D 227377 CDS NP_820998.1 29655306 1209938 1932869..1934032 1 NC_002971.3 O-succinylhomoserine (thiol)-lyase 1934032 metC 1209938 metC Coxiella burnetii RSA 493 O-succinylhomoserine (thiol)-lyase NP_820998.1 1932869 D 227377 CDS NP_821000.1 29655308 1209940 complement(1934771..1935058) 1 NC_002971.3 hypothetical protein 1935058 1209940 CBU_2027 Coxiella burnetii RSA 493 hypothetical protein NP_821000.1 1934771 R 227377 CDS NP_821001.1 29655309 1209941 complement(1935267..1936013) 1 NC_002971.3 hypothetical protein 1936013 1209941 CBU_2028 Coxiella burnetii RSA 493 hypothetical protein NP_821001.1 1935267 R 227377 CDS NP_821002.1 29655310 1209942 complement(1936107..1936739) 1 NC_002971.3 hypothetical protein 1936739 1209942 CBU_2029 Coxiella burnetii RSA 493 hypothetical protein NP_821002.1 1936107 R 227377 CDS NP_821003.1 29655311 1209943 1936877..1938058 1 NC_002971.3 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1938058 metK 1209943 metK Coxiella burnetii RSA 493 S-adenosylmethionine synthetase NP_821003.1 1936877 D 227377 CDS NP_821004.2 215919324 1209944 1938060..1939376 1 NC_002971.3 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 1939376 ahcY 1209944 ahcY Coxiella burnetii RSA 493 S-adenosyl-L-homocysteine hydrolase NP_821004.2 1938060 D 227377 CDS NP_821005.1 29655313 1209945 1939403..1940167 1 NC_002971.3 GAF domain-containing protein 1940167 1209945 CBU_2032 Coxiella burnetii RSA 493 GAF domain-containing protein NP_821005.1 1939403 D 227377 CDS NP_821006.1 29655314 1209946 complement(1940189..1940449) 1 NC_002971.3 hypothetical protein 1940449 1209946 CBU_2033 Coxiella burnetii RSA 493 hypothetical protein NP_821006.1 1940189 R 227377 CDS NP_821009.2 215919325 1209949 complement(1941777..1941953) 1 NC_002971.3 hypothetical protein 1941953 1209949 CBU_2036 Coxiella burnetii RSA 493 hypothetical protein NP_821009.2 1941777 R 227377 CDS NP_821012.1 29655320 1209953 1945802..1947130 1 NC_002971.3 HlyD family type I secretion membrane fusion protein 1947130 1209953 CBU_2040 Coxiella burnetii RSA 493 HlyD family type I secretion membrane fusion protein NP_821012.1 1945802 D 227377 CDS NP_821013.2 215919326 1209954 1947156..1947491 1 NC_002971.3 PAS domain-containing protein 1947491 1209954 CBU_2041 Coxiella burnetii RSA 493 PAS domain-containing protein NP_821013.2 1947156 D 227377 CDS NP_821017.1 29655325 1209959 complement(1951725..1951832) 1 NC_002971.3 hypothetical protein 1951832 1209959 CBU_2046 Coxiella burnetii RSA 493 hypothetical protein NP_821017.1 1951725 R 227377 CDS NP_821018.1 29655326 1209960 complement(1951911..1952783) 1 NC_002971.3 methylenetetrahydrofolate reductase 1952783 metF 1209960 metF Coxiella burnetii RSA 493 methylenetetrahydrofolate reductase NP_821018.1 1951911 R 227377 CDS NP_821019.1 29655327 1209961 complement(1952801..1955128) 1 NC_002971.3 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1955128 metE 1209961 metE Coxiella burnetii RSA 493 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase NP_821019.1 1952801 R 227377 CDS NP_821020.1 29655328 1209962 complement(1955313..1956383) 1 NC_002971.3 tryptophanyl-tRNA synthetase 1956383 trpS 1209962 trpS Coxiella burnetii RSA 493 tryptophanyl-tRNA synthetase NP_821020.1 1955313 R 227377 CDS YP_002333049.1 215919327 7065916 complement(1957578..1957817) 1 NC_002971.3 hypothetical protein 1957817 7065916 CBU_2051a Coxiella burnetii RSA 493 hypothetical protein YP_002333049.1 1957578 R 227377 CDS NP_821023.1 29655331 1209965 complement(1957881..1958783) 1 NC_002971.3 hypothetical protein 1958783 1209965 CBU_2052 Coxiella burnetii RSA 493 hypothetical protein NP_821023.1 1957881 R 227377 CDS NP_821025.2 215919328 1209967 1959158..1961329 1 NC_002971.3 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 1961329 uvrD 1209967 uvrD Coxiella burnetii RSA 493 DNA-dependent helicase II NP_821025.2 1959158 D 227377 CDS NP_821026.1 29655334 1209968 1961326..1962039 1 NC_002971.3 zinc uptake transporter 1962039 1209968 CBU_2055 Coxiella burnetii RSA 493 zinc uptake transporter NP_821026.1 1961326 D 227377 CDS NP_821027.2 215919329 1209969 complement(1962085..1962747) 1 NC_002971.3 hypothetical protein 1962747 1209969 CBU_2056 Coxiella burnetii RSA 493 hypothetical protein NP_821027.2 1962085 R 227377 CDS NP_821028.1 29655336 1209970 complement(1962936..1963913) 1 NC_002971.3 hypothetical protein 1963913 1209970 CBU_2057 Coxiella burnetii RSA 493 hypothetical protein NP_821028.1 1962936 R 227377 CDS NP_821029.1 29655337 1209971 complement(1964331..1965662) 1 NC_002971.3 proline/betaine transporter 1965662 1209971 CBU_2058 Coxiella burnetii RSA 493 proline/betaine transporter NP_821029.1 1964331 R 227377 CDS NP_821032.1 29655340 1209974 complement(1967569..1967706) 1 NC_002971.3 hypothetical protein 1967706 1209974 CBU_2061 Coxiella burnetii RSA 493 hypothetical protein NP_821032.1 1967569 R 227377 CDS NP_821036.1 29655344 1209978 complement(1969140..1969778) 1 NC_002971.3 hypothetical protein 1969778 1209978 CBU_2065 Coxiella burnetii RSA 493 hypothetical protein NP_821036.1 1969140 R 227377 CDS NP_821037.2 215919330 1209980 complement(1970594..1971994) 1 NC_002971.3 MFS superfamily transporter 1971994 1209980 CBU_2067 Coxiella burnetii RSA 493 MFS superfamily transporter NP_821037.2 1970594 R 227377 CDS NP_821038.1 29655346 1209981 complement(1971933..1973273) 1 NC_002971.3 MFS superfamily transporter 1973273 1209981 CBU_2068 Coxiella burnetii RSA 493 MFS superfamily transporter NP_821038.1 1971933 R 227377 CDS NP_821039.1 29655347 1209982 complement(1973414..1974004) 1 NC_002971.3 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1974004 1209982 CBU_2069 Coxiella burnetii RSA 493 thymidine kinase NP_821039.1 1973414 R 227377 CDS NP_821040.1 29655348 1209983 complement(1974021..1974431) 1 NC_002971.3 chorismate mutase 1974431 1209983 CBU_2070 Coxiella burnetii RSA 493 chorismate mutase NP_821040.1 1974021 R 227377 CDS NP_821041.1 29655349 1209984 1974507..1974989 1 NC_002971.3 hypothetical protein 1974989 1209984 CBU_2071 Coxiella burnetii RSA 493 hypothetical protein NP_821041.1 1974507 D 227377 CDS NP_821042.1 29655350 1209985 1975209..1975706 1 NC_002971.3 hypothetical protein 1975706 1209985 CBU_2072 Coxiella burnetii RSA 493 hypothetical protein NP_821042.1 1975209 D 227377 CDS NP_821043.1 29655351 1209986 1975742..1976644 1 NC_002971.3 acyltransferase 1976644 1209986 CBU_2073 Coxiella burnetii RSA 493 acyltransferase NP_821043.1 1975742 D 227377 CDS NP_821044.1 29655352 1209987 1976628..1977551 1 NC_002971.3 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1977551 hemC 1209987 hemC Coxiella burnetii RSA 493 porphobilinogen deaminase NP_821044.1 1976628 D 227377 CDS NP_821045.1 29655353 1209988 1977551..1978252 1 NC_002971.3 3-dehydroquinate dehydratase 1978252 aroD 1209988 aroD Coxiella burnetii RSA 493 3-dehydroquinate dehydratase NP_821045.1 1977551 D 227377 CDS NP_821046.1 29655354 1209989 1978262..1978579 1 NC_002971.3 hypothetical protein 1978579 1209989 CBU_2076 Coxiella burnetii RSA 493 hypothetical protein NP_821046.1 1978262 D 227377 CDS NP_821047.1 29655355 1209990 1978569..1979375 1 NC_002971.3 uroporphyrinogen-III synthase 1979375 hemD 1209990 hemD Coxiella burnetii RSA 493 uroporphyrinogen-III synthase NP_821047.1 1978569 D 227377 CDS NP_821048.1 29655356 1209991 complement(1979521..1980567) 1 NC_002971.3 Fic family protein 1980567 1209991 CBU_2078 Coxiella burnetii RSA 493 Fic family protein NP_821048.1 1979521 R 227377 CDS NP_821049.1 29655357 1209992 1980877..1981281 1 NC_002971.3 hypothetical protein 1981281 1209992 CBU_2079 Coxiella burnetii RSA 493 hypothetical protein NP_821049.1 1980877 D 227377 CDS NP_821050.2 215919331 1209993 1981362..1982324 1 NC_002971.3 uroporphyrin-III C-methyltransferase 1982324 1209993 CBU_2080 Coxiella burnetii RSA 493 uroporphyrin-III C-methyltransferase NP_821050.2 1981362 D 227377 CDS NP_821051.1 29655359 1209994 1982329..1983507 1 NC_002971.3 protein HemY 1983507 hemY 1209994 hemY Coxiella burnetii RSA 493 protein HemY NP_821051.1 1982329 D 227377 CDS NP_821052.2 215919332 1209995 1983510..1984277 1 NC_002971.3 hypothetical protein 1984277 1209995 CBU_2082 Coxiella burnetii RSA 493 hypothetical protein NP_821052.2 1983510 D 227377 CDS NP_821053.2 215919333 1209996 1984295..1985029 1 NC_002971.3 queuosine biosynthesis protein QueC 1985029 queC 1209996 queC Coxiella burnetii RSA 493 queuosine biosynthesis protein QueC NP_821053.2 1984295 D 227377 CDS NP_821054.1 29655362 1209997 1985305..1985424 1 NC_002971.3 hypothetical protein 1985424 1209997 CBU_2084 Coxiella burnetii RSA 493 hypothetical protein NP_821054.1 1985305 D 227377 CDS NP_821055.1 29655363 1209998 1985436..1985732 1 NC_002971.3 hypothetical protein 1985732 1209998 CBU_2085 Coxiella burnetii RSA 493 hypothetical protein NP_821055.1 1985436 D 227377 CDS NP_821056.1 29655364 1209999 complement(1985919..1987175) 1 NC_002971.3 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1987175 rho 1209999 rho Coxiella burnetii RSA 493 transcription termination factor Rho NP_821056.1 1985919 R 227377 CDS NP_821057.1 29655365 1210000 complement(1987351..1987689) 1 NC_002971.3 thioredoxin 1987689 trx 1210000 trx Coxiella burnetii RSA 493 thioredoxin NP_821057.1 1987351 R 227377 CDS NP_821058.1 29655366 1210001 1988102..1989454 1 NC_002971.3 sodium:neurotransmitter symporter family protein 1989454 1210001 CBU_2088 Coxiella burnetii RSA 493 sodium:neurotransmitter symporter family protein NP_821058.1 1988102 D 227377 CDS NP_821059.2 215919334 1210002 complement(1989549..1990130) 1 NC_002971.3 hypothetical protein 1990130 1210002 CBU_2089 Coxiella burnetii RSA 493 hypothetical protein NP_821059.2 1989549 R 227377 CDS NP_821060.1 29655368 1210003 complement(1990127..1990951) 1 NC_002971.3 pyrroline-5-carboxylate reductase 1990951 proC 1210003 proC Coxiella burnetii RSA 493 pyrroline-5-carboxylate reductase NP_821060.1 1990127 R 227377 CDS NP_821061.1 29655369 1210004 complement(1990948..1991634) 1 NC_002971.3 hypothetical protein 1991634 1210004 CBU_2091 Coxiella burnetii RSA 493 hypothetical protein NP_821061.1 1990948 R 227377 CDS NP_821062.1 29655370 1210005 complement(1991624..1993177) 1 NC_002971.3 ATP; PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 1993177 pckA 1210005 pckA Coxiella burnetii RSA 493 phosphoenolpyruvate carboxykinase NP_821062.1 1991624 R 227377 CDS NP_821063.2 215919335 1210006 1993272..1993856 1 NC_002971.3 transcriptional regulator 1993856 algH 1210006 algH Coxiella burnetii RSA 493 transcriptional regulator NP_821063.2 1993272 D 227377 CDS NP_821064.2 215919336 1210007 1993849..1994274 1 NC_002971.3 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1994274 1210007 CBU_2094 Coxiella burnetii RSA 493 Holliday junction resolvase-like protein NP_821064.2 1993849 D 227377 CDS NP_821065.1 29655373 1210008 1994267..1995199 1 NC_002971.3 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1995199 pyrB 1210008 pyrB Coxiella burnetii RSA 493 aspartate carbamoyltransferase NP_821065.1 1994267 D 227377 CDS NP_819020.1 29648115 1207831 79..537 1 NC_004704.1 similar to GP:4928261, and GP:4928261; identified by sequence similarity; putative; DNA-binding protein 537 1207831 CBUA0001 Coxiella burnetii RSA 493 DNA-binding protein NP_819020.1 79 D 227377 CDS NP_819022.1 29648117 1207833 671..1129 1 NC_004704.1 similar to GB:L20861, SP:P41221, and PID:348918; identified by sequence similarity; putative; hypothetical protein 1129 1207833 CBUA0003 Coxiella burnetii RSA 493 hypothetical protein NP_819022.1 671 D 227377 CDS NP_819024.1 29648119 1207836 2546..3571 1 NC_004704.1 similar to GP:4928257; identified by sequence similarity; putative; hypothetical protein 3571 1207836 CBUA0006 Coxiella burnetii RSA 493 hypothetical protein NP_819024.1 2546 D 227377 CDS NP_819025.1 29648120 1207837 complement(3769..4854) 1 NC_004704.1 similar to GP:2950335; identified by sequence similarity; putative; hypothetical protein 4854 1207837 CBUA0007 Coxiella burnetii RSA 493 hypothetical protein NP_819025.1 3769 R 227377 CDS NP_819027.1 29648122 1207840 complement(11375..12595) 1 NC_004704.1 similar to GP:2950326; identified by sequence similarity; putative; phage integrase family site specific recombinase 12595 1207840 CBUA0010 Coxiella burnetii RSA 493 phage integrase family site specific recombinase NP_819027.1 11375 R 227377 CDS NP_819028.1 29648123 1207841 12830..13000 1 NC_004704.1 similar to SP:P20628, and PID:142038; identified by sequence similarity; putative; hypothetical protein 13000 1207841 CBUA0011 Coxiella burnetii RSA 493 hypothetical protein NP_819028.1 12830 D 227377 CDS NP_819029.1 29648124 1207842 complement(13245..13760) 1 NC_004704.1 similar to GP:1070027; identified by sequence similarity; putative; hypothetical protein 13760 1207842 CBUA0012 Coxiella burnetii RSA 493 hypothetical protein NP_819029.1 13245 R 227377 CDS NP_819030.1 29648125 1207843 14418..15149 1 NC_004704.1 similar to GP:1070026; identified by sequence similarity; putative; hypothetical protein 15149 1207843 CBUA0013 Coxiella burnetii RSA 493 hypothetical protein NP_819030.1 14418 D 227377 CDS NP_819031.1 29648126 1207844 15536..15769 1 NC_004704.1 identified by match to PFAM protein family HMM PF00646; hypothetical protein 15769 1207844 CBUA0014 Coxiella burnetii RSA 493 hypothetical protein NP_819031.1 15536 D 227377 CDS NP_819032.1 29648127 1207845 16225..16662 1 NC_004704.1 similar to GP:580968; identified by sequence similarity; putative; hypothetical protein 16662 1207845 CBUA0015 Coxiella burnetii RSA 493 hypothetical protein NP_819032.1 16225 D 227377 CDS NP_819033.1 29648128 1207846 16686..17711 1 NC_004704.1 similar to GP:407389; identified by sequence similarity; putative; CbhE protein 17711 1207846 CBUA0016 Coxiella burnetii RSA 493 CbhE protein NP_819033.1 16686 D 227377 CDS NP_819034.1 29648129 1207847 complement(17739..17945) 1 NC_004704.1 hypothetical protein 17945 1207847 CBUA0017 Coxiella burnetii RSA 493 hypothetical protein NP_819034.1 17739 R 227377 CDS NP_819037.1 29648132 1207850 complement(19736..20587) 1 NC_004704.1 hypothetical protein 20587 1207850 CBUA0020 Coxiella burnetii RSA 493 hypothetical protein NP_819037.1 19736 R 227377 CDS NP_819038.1 29648133 1207851 complement(20614..21666) 1 NC_004704.1 similar to GP:580964; identified by sequence similarity; putative; hypothetical protein 21666 1207851 CBUA0021 Coxiella burnetii RSA 493 hypothetical protein NP_819038.1 20614 R 227377 CDS NP_819039.1 29648134 1207852 22124..22435 1 NC_004704.1 hypothetical protein 22435 1207852 CBUA0022 Coxiella burnetii RSA 493 hypothetical protein NP_819039.1 22124 D 227377 CDS NP_819040.1 29648135 1207853 complement(22568..23269) 1 NC_004704.1 similar to GB:X67055, GB:X14690, PID:1628399, PID:288563, and PID:35465; identified by sequence similarity; putative; hypothetical protein 23269 1207853 CBUA0023 Coxiella burnetii RSA 493 hypothetical protein NP_819040.1 22568 R 227377 CDS NP_819041.1 29648136 1207854 23713..24156 1 NC_004704.1 similar to GP:2706540; identified by sequence similarity; putative; hypothetical protein 24156 1207854 CBUA0024 Coxiella burnetii RSA 493 hypothetical protein NP_819041.1 23713 D 227377 CDS NP_819042.1 29648137 1207855 complement(24282..24542) 1 NC_004704.1 similar to GB:U03842, SP:P40676, PID:438375, GB:U03842, SP:P40676, and PID:438375; identified by sequence similarity; putative; hypothetical protein 24542 1207855 CBUA0025 Coxiella burnetii RSA 493 hypothetical protein NP_819042.1 24282 R 227377 CDS NP_819043.1 29648138 1207856 24901..25131 1 NC_004704.1 hypothetical protein 25131 1207856 CBUA0026 Coxiella burnetii RSA 493 hypothetical protein NP_819043.1 24901 D 227377 CDS NP_819044.1 29648139 1207857 complement(25379..25720) 1 NC_004704.1 similar to GP:1070023, and GP:1070023; identified by sequence similarity; putative; DNA-binding protein 25720 1207857 CBUA0027 Coxiella burnetii RSA 493 DNA-binding protein NP_819044.1 25379 R 227377 CDS NP_819045.1 29648140 1207858 complement(25720..26085) 1 NC_004704.1 similar to GP:15075491; identified by sequence similarity; putative; hypothetical protein 26085 1207858 CBUA0028 Coxiella burnetii RSA 493 hypothetical protein NP_819045.1 25720 R 227377 CDS NP_819047.1 29648142 1207861 28244..28864 1 NC_004704.1 similar to GB:L20316, GB:U03469, SP:P47871, PID:405190, PID:439690, and PID:553305; identified by sequence similarity; putative; hypothetical protein 28864 1207861 CBUA0031 Coxiella burnetii RSA 493 hypothetical protein NP_819047.1 28244 D 227377 CDS NP_819048.1 29648143 1207862 28854..29600 1 NC_004704.1 similar to GP:757768; identified by sequence similarity; putative; Ser/Thr protein phosphatase family protein 29600 1207862 CBUA0032 Coxiella burnetii RSA 493 Ser/Thr protein phosphatase family protein NP_819048.1 28854 D 227377 CDS NP_819049.1 29648144 1207863 29790..30143 1 NC_004704.1 hypothetical protein 30143 1207863 CBUA0033 Coxiella burnetii RSA 493 hypothetical protein NP_819049.1 29790 D 227377 CDS NP_819050.1 29648145 1207864 complement(30413..30619) 1 NC_004704.1 hypothetical protein 30619 1207864 CBUA0034 Coxiella burnetii RSA 493 hypothetical protein NP_819050.1 30413 R 227377 CDS NP_819051.1 29648146 1207866 complement(31549..32418) 1 NC_004704.1 similar to GP:4928233; identified by sequence similarity; putative; parB protein, putative 32418 1207866 CBUA0036 Coxiella burnetii RSA 493 parB protein, putative NP_819051.1 31549 R 227377 CDS NP_819052.1 29648147 1207867 32782..34002 1 NC_004704.1 similar to SP:P08866, GB:X16064, GB:L13806, SP:P13693, and PID:37496; identified by sequence similarity; putative; parA protein, putative 34002 1207867 CBUA0037 Coxiella burnetii RSA 493 parA protein, putative NP_819052.1 32782 D 227377 CDS NP_819053.1 29648148 1207868 33995..34999 1 NC_004704.1 similar to GP:407373, and GP:6425160; identified by sequence similarity; putative; repB protein, putative 34999 1207868 CBUA0038 Coxiella burnetii RSA 493 repB protein, putative NP_819053.1 33995 D 227377 CDS NP_819054.1 29648149 1207869 35056..36345 1 NC_004704.1 similar to GP:757813, and GP:18029507; identified by sequence similarity; putative; repA protein, putative 36345 1207869 CBUA0039 Coxiella burnetii RSA 493 repA protein, putative NP_819054.1 35056 D 227377 CDS NP_819055.1 29648150 1207870 36400..36978 1 NC_004704.1 hypothetical protein 36978 1207870 CBUA0040 Coxiella burnetii RSA 493 hypothetical protein NP_819055.1 36400 D 227377 CDS