-- dump date 20140619_055901 -- class Genbank::CDS -- table cds_note -- id note YP_180756.1 identified by similarity to SP:P05648; match to protein family HMM TIGR00362 YP_180757.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_180758.1 identified by match to protein family HMM TIGR00125; match to protein family HMM TIGR00482 YP_180759.1 identified by match to protein family HMM PF00204; match to protein family HMM PF00986 YP_180760.1 identified by similarity to SP:O54408; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_180761.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_180763.1 identified by similarity to OMNI:EF1643 YP_180764.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_180766.1 identified by match to protein family HMM PF00817 YP_180767.1 identified by similarity to OMNI:NTL01TT2569 YP_180768.1 identified by similarity to SP:Q9P9M3; match to protein family HMM TIGR02127 YP_180771.1 identified by similarity to GP:4930039; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01499 YP_180774.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_180775.1 identified by similarity to OMNI:NTL01TT1159 YP_180776.1 identified by similarity to OMNI:MJ1433 YP_180779.1 identified by match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_180780.1 identified by similarity to SP:P39694 YP_180781.1 identified by similarity to SP:P23868; match to protein family HMM PF02080 YP_180782.1 identified by similarity to SP:Q53949 YP_180784.1 identified by similarity to SP:P21166 YP_180785.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_180787.1 identified by match to protein family HMM TIGR01297 YP_180788.1 identified by similarity to OMNI:NTL01CA3047 YP_180790.1 Essential for recycling GMP and indirectly, cGMP YP_180793.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_180794.1 identified by similarity to GP:12248364 YP_180796.1 identified by similarity to SP:P31113 YP_180798.1 identified by similarity to SP:P08986 YP_180799.1 identified by similarity to GP:29607780 YP_180800.1 identified by similarity to OMNI:CT0642; match to protein family HMM TIGR01909 YP_180801.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_180802.1 identified by similarity to SP:P28630 YP_180803.1 identified by similarity to GP:10198137 YP_180804.1 identified by match to protein family HMM PF00480 YP_180805.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_180806.1 identified by similarity to GP:28203196; match to protein family HMM TIGR00250 YP_180807.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_180810.1 identified by similarity to SP:P37571; match to protein family HMM PF00004; match to protein family HMM PF02861 YP_180811.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_180812.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_180813.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_180814.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_180817.1 identified by similarity to GP:3482866 YP_180818.1 identified by match to protein family HMM PF01555; match to protein family HMM PF02195 YP_180819.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_180824.1 identified by match to protein family HMM TIGR01613 YP_180825.1 identified by similarity to OMNI:AF2353 YP_180826.1 identified by similarity to SP:P06225 YP_180830.1 identified by similarity to GP:27228279 YP_180831.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_180834.1 identified by similarity to GP:2645860 YP_180835.1 identified by similarity to SP:P21891 YP_180837.1 identified by similarity to SP:P23873 YP_180839.1 identified by similarity to GP:8163916 YP_180843.1 identified by similarity to GP:29899002 YP_180846.1 identified by similarity to SP:P33650; match to protein family HMM TIGR00231; match to protein family HMM TIGR00437 YP_180847.1 identified by match to protein family HMM PF04023 YP_180848.1 identified by match to protein family HMM PF02742 YP_180849.1 identified by similarity to OMNI:NTL01PH01780 YP_180852.1 identified by match to protein family HMM PF00384; match to protein family HMM PF04879 YP_180854.1 identified by similarity to SP:P32708 YP_180856.1 identified by similarity to GP:28202560; match to protein family HMM TIGR00762 YP_180857.1 identified by match to protein family HMM PF04011 YP_180859.1 identified by match to protein family HMM PF03372 YP_180860.1 identified by similarity to SP:P37182; match to protein family HMM TIGR00072 YP_180861.1 identified by similarity to SP:P21852 YP_180862.1 identified by similarity to SP:P12943; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_180863.1 identified by similarity to SP:P33389 YP_180865.1 identified by similarity to SP:P46904 YP_180866.1 identified by similarity to SP:P75774; similarity to OMNI:NTL01BMA0802 YP_180867.1 identified by similarity to GB:AAN59033.1 YP_180868.1 identified by match to protein family HMM TIGR01383 YP_180869.1 catalyzes the formation of oxaloacetate from pyruvate YP_180870.1 catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate YP_180871.1 identified by similarity to OMNI:NTL01MT01686 YP_180875.1 identified by similarity to SP:P39400 YP_180876.1 identified by similarity to SP:P22096; match to protein family HMM TIGR01245 YP_180877.1 identified by match to protein family HMM TIGR00229 YP_180878.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_180879.1 identified by similarity to OMNI:TM1872; match to protein family HMM PF01894 YP_180880.1 identified by similarity to SP:P13792 YP_180881.1 identified by similarity to SP:Q00934 YP_180883.1 identified by similarity to OMNI:TM1786 YP_180885.1 identified by similarity to GB:BAA02453.1 YP_180886.1 identified by similarity to OMNI:NTL01BH3159; match to protein family HMM TIGR00229 YP_180887.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_180888.1 identified by match to protein family HMM TIGR02136 YP_180889.1 identified by similarity to GP:4530448 YP_180891.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_180892.1 identified by similarity to SP:P07656; match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_180893.1 identified by similarity to SP:P30330 YP_180894.1 identified by similarity to OMNI:PSPTO1011 YP_180895.1 identified by similarity to GP:2865515 YP_180896.1 identified by similarity to GP:5650749; match to protein family HMM PF01512 YP_180897.1 identified by similarity to GP:14250935; match to protein family HMM PF02256 YP_180898.1 identified by similarity to GP:14250936 YP_180899.1 identified by similarity to OMNI:MT0192 YP_180900.1 identified by similarity to OMNI:NTL01MM2721 YP_180901.1 identified by match to protein family HMM PF01863 YP_180903.1 identified by similarity to GP:560723 YP_180904.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_180906.1 identified by match to protein family HMM PF00589 YP_180910.1 identified by similarity to GP:27360617 YP_180913.1 identified by similarity to SP:P24580 YP_180914.1 identified by similarity to GP:2645861; match to protein family HMM PF00665 YP_180915.1 identified by similarity to OMNI:NTL02SC5407 YP_180917.1 identified by similarity to SP:Q45585 YP_180919.1 identified by match to protein family HMM TIGR00229 YP_180921.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_180923.1 identified by similarity to GP:27462922 YP_180926.1 identified by similarity to SP:P35164 YP_180928.1 identified by similarity to GP:3002555; similarity to GP:5531941; match to protein family HMM TIGR01409 YP_180929.1 identified by similarity to GP:27228279 YP_180931.1 identified by similarity to SP:P25888 YP_180935.1 identified by match to protein family HMM TIGR01409; match to protein family HMM TIGR01553 YP_180937.1 identified by match to protein family HMM TIGR00095 YP_180938.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_180941.1 identified by match to protein family HMM TIGR00112 YP_180942.1 identified by similarity to SP:P36430 YP_180945.1 identified by similarity to OMNI:NTL01MT00097 YP_180946.1 identified by similarity to SP:P23171 YP_180947.1 identified by similarity to SP:P51386 YP_180948.1 identified by similarity to OMNI:NTL01MM1194 YP_180949.1 identified by similarity to SP:P71243 YP_180950.1 identified by match to protein family HMM TIGR01656; match to protein family HMM TIGR01662 YP_180953.1 identified by similarity to GP:13491145 YP_180954.1 identified by similarity to GP:13491143 YP_180955.1 identified by similarity to SP:Q9AGY7 YP_180960.1 identified by similarity to OMNI:SO3266 YP_180961.1 identified by similarity to OMNI:NTL01MT00337 YP_180962.1 identified by similarity to SP:P19499; match to protein family HMM PF04422 YP_180964.1 identified by similarity to OMNI:DRA0063; match to protein family HMM PF02585 YP_180965.1 identified by match to protein family HMM PF00248 YP_180966.1 identified by match to protein family HMM PF02001 YP_180967.1 identified by match to protein family HMM PF03130 YP_180969.1 identified by similarity to GP:5410603; match to protein family HMM TIGR00238 YP_180970.1 identified by match to protein family HMM PF00079 YP_180972.1 identified by similarity to SP:P45535 YP_180974.1 identified by similarity to OMNI:NTL01CA3526; match to protein family HMM PF03486 YP_180978.1 identified by similarity to OMNI:NTL02LI0782; match to protein family HMM PF05154 YP_180981.1 identified by similarity to OMNI:NTL02MA3318; match to protein family HMM TIGR00229 YP_180983.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_180984.1 identified by similarity to GP:27462922 YP_180985.1 identified by similarity to GP:7710206 YP_180986.1 identified by similarity to OMNI:NTL03CP1044; match to protein family HMM TIGR00290 YP_180992.1 identified by similarity to OMNI:TM0118; match to protein family HMM PF00317; match to protein family HMM PF02867 YP_180993.1 identified by similarity to SP:P13040 YP_180994.1 identified by match to protein family HMM TIGR00380 YP_180995.1 identified by similarity to OMNI:CT0027 YP_180996.1 identified by similarity to SP:O54055 YP_180997.1 identified by similarity to OMNI:MJ1613 YP_180998.1 identified by similarity to OMNI:NTL01TT0342 YP_180999.1 identified by similarity to SP:P31080 YP_181001.1 identified by similarity to SP:Q08346 YP_181017.1 identified by similarity to OMNI:NTL02MA0434 YP_181018.1 identified by match to protein family HMM TIGR01612 YP_181022.1 identified by similarity to SP:P31080 YP_181024.1 identified by similarity to SP:Q08346 YP_181030.1 identified by similarity to OMNI:NTL03SA2242 YP_181040.1 identified by similarity to OMNI:NTL03PA00694 YP_181041.1 identified by match to protein family HMM TIGR01612 YP_181044.1 identified by similarity to SP:P21921; similarity to SP:Q10671; match to protein family HMM PF00590 YP_181045.1 identified by similarity to OMNI:NTL01MM2691 YP_181047.1 identified by match to protein family HMM PF00027 YP_181049.1 identified by match to protein family HMM TIGR00229 YP_181050.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_181051.1 identified by similarity to GP:27228279 YP_181053.1 identified by similarity to OMNI:NTL01MM3099; match to protein family HMM TIGR00229 YP_181054.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_181055.1 identified by similarity to GP:27228279 YP_181056.1 identified by similarity to SP:Q58075 YP_181058.1 identified by similarity to GP:7710206 YP_181059.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_181060.1 identified by similarity to GP:27228279 YP_181062.1 identified by similarity to OMNI:MJ1613 YP_181063.1 identified by similarity to OMNI:NTL02MA3318; match to protein family HMM TIGR00229 YP_181066.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_181067.1 identified by similarity to GP:27228279 YP_181072.1 identified by match to protein family HMM PF01734 YP_181073.1 identified by similarity to OMNI:NTL01TE2094; match to protein family HMM PF01935 YP_181074.1 identified by similarity to OMNI:NTL01SS00170 YP_181075.1 identified by similarity to OMNI:NTL01NS3859 YP_181077.1 identified by match to protein family HMM PF00850 YP_181078.1 identified by similarity to GP:18378082; match to protein family HMM TIGR01297 YP_181079.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_181080.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_181081.1 identified by match to protein family HMM PF01743 YP_181084.1 identified by match to protein family HMM TIGR00595 YP_181085.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_181086.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_181087.1 identified by similarity to GP:27315315; match to protein family HMM TIGR00242 YP_181088.1 identified by similarity to SP:Q97H81; match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_181089.1 identified by similarity to SP:P06137; match to protein family HMM TIGR01174 YP_181090.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_181091.1 identified by similarity to SP:Q8R9H6; match to protein family HMM TIGR00244 YP_181092.1 Catalyzes the rate-limiting step in dNTP synthesis YP_181094.1 identified by similarity to OMNI:NTL02ML6114 YP_181095.1 identified by similarity to OMNI:NTL01TT0848 YP_181096.1 identified by similarity to OMNI:TM0690; match to protein family HMM PF02637 YP_181097.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_181099.1 identified by similarity to GB:BAC73118.1 YP_181101.1 identified by similarity to GP:29895579 YP_181106.1 identified by similarity to OMNI:NTL01CJ00668 YP_181110.1 identified by similarity to SP:Q44879; match to protein family HMM PF03572; match to protein family HMM TIGR00225 YP_181111.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_181112.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_181113.1 catalyzes the hydrolysis of pyrophosphate YP_181114.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_181115.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_181117.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_181118.1 identified by similarity to SP:O31752 YP_181119.1 identified by similarity to SP:O82827; match to protein family HMM PF01255; match to protein family HMM TIGR00055 YP_181120.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_181121.1 Catalyzes the phosphorylation of UMP to UDP YP_181122.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_181123.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_181124.1 identified by similarity to SP:O29008; match to protein family HMM TIGR01737 YP_181125.1 identified by similarity to GB:AAA22679.1; match to protein family HMM TIGR01736 YP_181126.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_181127.1 identified by match to protein family HMM PF00355 YP_181129.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_181131.1 identified by similarity to OMNI:NTL01NS4675; match to protein family HMM TIGR00096 YP_181133.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_181134.1 identified by similarity to SP:P55785; match to protein family HMM PF00348 YP_181136.1 identified by similarity to SP:P37476; match to protein family HMM PF06480; match to protein family HMM TIGR01241 YP_181138.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_181139.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_181140.1 identified by match to protein family HMM PF00814; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR02009 YP_181141.1 identified by similarity to GP:29894046; match to protein family HMM TIGR00150 YP_181142.1 identified by match to protein family HMM TIGR01379 YP_181143.1 identified by similarity to SP:P27851 YP_181144.1 identified by similarity to SP:P27851 YP_181145.1 identified by match to protein family HMM PF01761 YP_181146.1 identified by similarity to SP:P32166 YP_181148.1 identified by similarity to OMNI:NTL01MK0801 YP_181149.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_181150.1 identified by match to protein family HMM TIGR00154 YP_181152.1 identified by similarity to OMNI:NTL03ST4202 YP_181153.1 identified by similarity to OMNI:NTL01XC3234 YP_181155.1 identified by similarity to SP:P23703 YP_181156.1 identified by similarity to SP:P55475 YP_181157.1 identified by similarity to SP:Q58794 YP_181158.1 identified by similarity to SP:O22000; match to protein family HMM PF00383 YP_181159.1 identified by similarity to OMNI:TM0358; match to protein family HMM TIGR00147 YP_181160.1 catalyzes the formation of UMP from UTP YP_181161.1 identified by similarity to OMNI:NTL01MM2338; similarity to OMNI:NTL03CP2599 YP_181162.1 identified by similarity to SP:P48243 YP_181163.1 identified by match to protein family HMM TIGR01726 YP_181164.1 identified by similarity to SP:P30860; similarity to SP:P39174 YP_181166.1 identified by similarity to GP:28202560; match to protein family HMM TIGR00762 YP_181168.1 identified by match to protein family HMM PF01544 YP_181169.1 identified by match to protein family HMM TIGR00697 YP_181171.1 identified by match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_181172.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_181173.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR00521 YP_181174.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_181175.1 identified by match to protein family HMM TIGR00229 YP_181176.1 identified by similarity to SP:P54662 YP_181178.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_181179.1 identified by similarity to GB:CAA58682.1; match to protein family HMM TIGR01251 YP_181180.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_181181.1 identified by similarity to GP:21464612; match to protein family HMM TIGR00758 YP_181182.1 identified by similarity to GP:28203198; match to protein family HMM TIGR00649 YP_181185.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_181186.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_181187.1 identified by similarity to SP:P24239; match to protein family HMM TIGR00228 YP_181188.1 identified by similarity to OMNI:CT1665; match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_181189.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00516; match to protein family HMM TIGR00556 YP_181190.1 identified by similarity to GP:2865515 YP_181191.1 identified by match to protein family HMM PF01039 YP_181192.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_181193.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_181194.1 identified by similarity to SP:P33197; match to protein family HMM PF00180 YP_181195.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_181197.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid YP_181198.1 identified by similarity to SP:P14407; match to protein family HMM PF05683; match to protein family HMM TIGR00723 YP_181201.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_181202.1 identified by similarity to GP:27262282 YP_181204.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_181206.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_181207.1 identified by match to protein family HMM PF00275; match to protein family HMM TIGR01356 YP_181208.1 identified by similarity to SP:P24167 YP_181209.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_181210.1 identified by similarity to SP:P05194; match to protein family HMM PF01487; match to protein family HMM TIGR01093 YP_181211.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_181212.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_181214.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_181215.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_181216.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_181217.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_181218.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_181219.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_181220.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_181221.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_181222.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_181223.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_181224.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_181225.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_181226.1 one of the stabilizing components for the large ribosomal subunit YP_181227.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_181228.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_181229.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_181230.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_181231.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_181232.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_181233.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_181234.1 binds 5S rRNA along with protein L5 and L25 YP_181235.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_181236.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_181237.1 late assembly protein YP_181238.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_181239.1 identified by similarity to SP:P27142; match to protein family HMM TIGR01351 YP_181240.1 identified by similarity to SP:P19994; match to protein family HMM TIGR00500 YP_181241.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_181242.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_181243.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_181244.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_181245.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_181246.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_181247.1 is a component of the macrolide binding site in the peptidyl transferase center YP_181248.1 identified by match to protein family HMM PF01416; match to protein family HMM TIGR00071 YP_181249.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_181250.1 forms a direct contact with the tRNA during translation YP_181253.1 catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate YP_181254.1 identified by similarity to OMNI:CT0279 YP_181255.1 identified by similarity to OMNI:NTL01PH00939 YP_181256.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_181257.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_181258.1 identified by similarity to OMNI:NTL01NS4782 YP_181259.1 identified by similarity to OMNI:TM0518 YP_181260.1 identified by similarity to OMNI:NTL02SC5267 YP_181261.1 identified by similarity to GP:5542154; match to protein family HMM TIGR01694 YP_181262.1 identified by match to protein family HMM PF01008; match to protein family HMM TIGR00512; match to protein family HMM TIGR00524 YP_181263.1 identified by similarity to OMNI:NTL01BMA0802 YP_181264.1 identified by similarity to OMNI:TM1403; match to protein family HMM TIGR01188 YP_181265.1 identified by similarity to OMNI:NTL01OI0672 YP_181266.1 identified by similarity to OMNI:NTL01ML1916 YP_181267.1 identified by similarity to GP:23978678 YP_181269.1 identified by similarity to OMNI:AF0525 YP_181271.1 identified by similarity to SP:P46473 YP_181272.1 identified by match to protein family HMM PF02880 YP_181273.1 identified by similarity to GP:1814004 YP_181274.1 identified by similarity to SP:P08075 YP_181275.1 identified by similarity to SP:Q56213; match to protein family HMM TIGR01135 YP_181276.1 identified by match to protein family HMM PF01161; match to protein family HMM TIGR00481 YP_181277.1 identified by match to protein family HMM TIGR01549 YP_181278.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01048 YP_181279.1 identified by similarity to SP:P37540 YP_181280.1 identified by match to protein family HMM PF04468 YP_181282.1 identified by similarity to SP:P07905 YP_181283.1 identified by match to protein family HMM TIGR01446 YP_181284.1 identified by match to protein family HMM PF00772; match to protein family HMM TIGR00665 YP_181285.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_181286.1 identified by match to protein family HMM TIGR01292 YP_181287.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_181288.1 identified by match to protein family HMM TIGR00241 YP_181289.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891 YP_181290.1 identified by similarity to SP:O34863; match to protein family HMM TIGR00630 YP_181291.1 identified by match to protein family HMM TIGR00277 YP_181293.1 identified by similarity to SP:P13458 YP_181295.1 identified by similarity to SP:P06224; match to protein family HMM PF00140; match to protein family HMM PF04539 YP_181296.1 identified by match to protein family HMM TIGR01391 YP_181297.1 dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_181298.1 identified by match to protein family HMM PF00391; match to protein family HMM TIGR01418 YP_181301.1 identified by match to protein family HMM TIGR01131 YP_181302.1 identified by match to protein family HMM TIGR01260 YP_181303.1 identified by match to protein family HMM TIGR01144 YP_181304.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_181305.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_181306.1 identified by match to protein family HMM PF00231; match to protein family HMM TIGR01146 YP_181307.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_181308.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_181309.1 identified by similarity to SP:P21504 YP_181310.1 identified by similarity to SP:Q8XJP5 YP_181311.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_181312.1 identified by match to protein family HMM PF04493 YP_181313.1 identified by similarity to GB:CAB15546.1; match to protein family HMM PF03462; match to protein family HMM TIGR00020 YP_181315.1 identified by match to protein family HMM TIGR00608 YP_181316.1 identified by similarity to SP:P23843 YP_181319.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_181320.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_181322.1 identified by match to protein family HMM PF02565; match to protein family HMM TIGR00613 YP_181324.1 identified by similarity to OMNI:NTL02MA1674; match to protein family HMM TIGR00383 YP_181325.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_181326.1 identified by similarity to SP:Q8RDI5 YP_181327.1 identified by similarity to SP:P09122 YP_181329.1 identified by similarity to OMNI:NTL01CA2954 YP_181330.1 identified by similarity to OMNI:NTL01TT1546 YP_181332.1 identified by match to protein family HMM PF00044; match to protein family HMM TIGR01534 YP_181333.1 identified by similarity to OMNI:NTL01CA3558 YP_181335.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_181336.1 identified by match to protein family HMM TIGR00725 YP_181337.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_181338.1 identified by match to protein family HMM TIGR00575 YP_181339.1 identified by similarity to OMNI:CT0137 YP_181340.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_181341.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_181342.1 identified by similarity to SP:P16421 YP_181343.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_181344.1 identified by similarity to SP:Q59263; match to protein family HMM PF01687; match to protein family HMM TIGR00083 YP_181345.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_181346.1 identified by similarity to SP:P37871; match to protein family HMM PF00623; match to protein family HMM PF04983; match to protein family HMM PF04997; match to protein family HMM PF04998 YP_181348.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_181349.1 identified by match to protein family HMM PF02677 YP_181350.1 identified by match to protein family HMM TIGR01575 YP_181352.1 identified by similarity to GP:20905475 YP_181353.1 identified by similarity to GP:5199108 YP_181354.1 identified by match to protein family HMM TIGR01211 YP_181356.1 identified by similarity to GP:1747407 YP_181357.1 identified by similarity to GP:1747408 YP_181358.1 identified by similarity to SP:P19930; match to protein family HMM TIGR00072 YP_181360.1 identified by similarity to SP:P35160 YP_181361.1 identified by similarity to SP:P45706 YP_181362.1 identified by similarity to GP:28410532 YP_181363.1 identified by similarity to OMNI:NTL01BH1315 YP_181365.1 identified by similarity to OMNI:TM0118 YP_181366.1 identified by similarity to OMNI:TM0186; match to protein family HMM TIGR00277 YP_181367.1 identified by match to protein family HMM TIGR00229 YP_181368.1 identified by similarity to OMNI:SAG1430 YP_181370.1 identified by match to protein family HMM TIGR00238 YP_181374.1 identified by similarity to SP:Q9XDA6 YP_181375.1 identified by similarity to GP:5019735 YP_181378.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_181379.1 identified by similarity to SP:P28264; match to protein family HMM TIGR01174 YP_181385.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_181386.1 identified by match to protein family HMM TIGR00232 YP_181388.1 identified by similarity to OMNI:NTL02MA4536 YP_181390.1 identified by similarity to OMNI:NTL04PA0672 YP_181392.1 identified by similarity to OMNI:NTL01TT0342 YP_181393.1 identified by similarity to PIR:S54438 YP_181394.1 identified by similarity to SP:P23878 YP_181395.1 identified by similarity to OMNI:MJ1613 YP_181396.1 identified by match to protein family HMM TIGR00380 YP_181397.1 identified by similarity to SP:P17731 YP_181399.1 identified by similarity to SP:P36562 YP_181400.1 identified by similarity to SP:P36561; match to protein family HMM TIGR00317 YP_181401.1 identified by similarity to SP:P52086 YP_181402.1 identified by similarity to SP:P46886 YP_181403.1 identified by match to protein family HMM TIGR01068 YP_181407.1 part of a complex that catalyzes the cleavage of acetyl-CoA YP_181408.1 in acetogenic organisms, this enzyme complex converts carbon dioxide to acetyl-CoA while in methanogenic organisms this enzyme is used to degrade acetyl-CoA to form methane and carbon dioxide; part of an enzyme complex YP_181409.1 part of a complex that catalyzes the cleavage of acetyl-CoA YP_181410.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_181411.1 identified by similarity to GP:20467243; match to protein family HMM PF00991 YP_181413.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_181417.1 identified by match to protein family HMM PF04199 YP_181419.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_181420.1 identified by match to protein family HMM TIGR00232 YP_181421.1 identified by similarity to OMNI:NTL01CA1531 YP_181422.1 identified by similarity to OMNI:NTL02MA4536 YP_181424.1 identified by similarity to OMNI:NTL04PA0672 YP_181426.1 identified by similarity to OMNI:NTL01TT0342 YP_181427.1 identified by similarity to PIR:S54438 YP_181428.1 identified by similarity to SP:P23878 YP_181429.1 identified by similarity to OMNI:MJ1613 YP_181430.1 identified by match to protein family HMM TIGR00380 YP_181431.1 identified by similarity to SP:P17731 YP_181433.1 identified by similarity to SP:P36562 YP_181434.1 identified by similarity to SP:P36561; match to protein family HMM TIGR00317 YP_181435.1 identified by similarity to SP:P52086 YP_181436.1 identified by similarity to SP:P46886 YP_181437.1 identified by similarity to SP:P06544; match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_181438.1 identified by similarity to SP:P55184 YP_181440.1 part of a complex that catalyzes the cleavage of acetyl-CoA YP_181441.1 in acetogenic organisms, this enzyme complex converts carbon dioxide to acetyl-CoA while in methanogenic organisms this enzyme is used to degrade acetyl-CoA to form methane and carbon dioxide; part of an enzyme complex YP_181442.1 part of a complex that catalyzes the cleavage of acetyl-CoA YP_181443.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_181444.1 identified by similarity to GP:20467243; match to protein family HMM PF00991 YP_181445.1 identified by match to protein family HMM PF00111 YP_181446.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_181449.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_181450.1 identified by similarity to SP:P80698; match to protein family HMM PF00254; match to protein family HMM TIGR00115 YP_181451.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_181453.1 identified by similarity to SP:P08179 YP_181454.1 identified by match to protein family HMM PF02811 YP_181456.1 identified by similarity to SP:P76524; similarity to GP:1915907 YP_181458.1 identified by similarity to SP:P39814; match to protein family HMM PF01131; match to protein family HMM TIGR01051 YP_181459.1 identified by match to protein family HMM TIGR00732 YP_181461.1 identified by similarity to SP:P26235 YP_181462.1 identified by similarity to SP:Q51799 YP_181463.1 identified by similarity to SP:Q51803 YP_181464.1 identified by similarity to SP:Q51804 YP_181465.1 identified by similarity to SP:Q51805 YP_181466.1 identified by similarity to GP:14250933 YP_181467.1 identified by similarity to GP:14250934 YP_181468.1 identified by similarity to GP:1032477 YP_181469.1 identified by similarity to SP:P16171; match to protein family HMM PF02852 YP_181470.1 identified by similarity to SP:Q50229 YP_181471.1 identified by similarity to SP:P37769 YP_181472.1 identified by similarity to SP:P25519 YP_181474.1 catalyzes the formation of LL-diaminopimelate from tetrahydrodipicolinate; involved in lysine and peptidoglycan synthesis YP_181475.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_181476.1 identified by match to protein family HMM PF01715; match to protein family HMM TIGR00174 YP_181477.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_181478.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM YP_181479.1 identified by similarity to SP:P40924; match to protein family HMM PF00162 YP_181480.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_181481.1 identified by similarity to OMNI:SAG1830 YP_181483.1 identified by similarity to SP:P37472; match to protein family HMM TIGR01203 YP_181484.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_181485.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_181486.1 identified by similarity to SP:O53084; match to protein family HMM PF05198; match to protein family HMM TIGR00168 YP_181487.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_181490.1 identified by similarity to OMNI:NTL03CP0415 YP_181491.1 identified by match to protein family HMM TIGR00044 YP_181492.1 identified by match to protein family HMM TIGR01488; match to protein family HMM TIGR01489 YP_181493.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_181496.1 identified by similarity to OMNI:NTL01MM1779 YP_181498.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_181499.1 identified by similarity to SP:P20603 YP_181500.1 identified by similarity to OMNI:NTL01PF1439; match to protein family HMM PF03675 YP_181502.1 identified by similarity to SP:P80240; match to protein family HMM PF01272; match to protein family HMM PF03449 YP_181503.1 identified by similarity to OMNI:NTL01MM3299 YP_181505.1 identified by similarity to OMNI:NTL01MM1149 YP_181507.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_181508.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_181510.1 identified by similarity to SP:P37537; match to protein family HMM TIGR00041 YP_181511.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_181512.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_181513.1 identified by similarity to SP:Q9HVZ1; match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_181514.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_181515.1 identified by similarity to OMNI:NTL02MA0091; match to protein family HMM PF01997 YP_181516.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_181519.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_181520.1 identified by match to protein family HMM TIGR00619 YP_181521.1 identified by similarity to SP:Q55578; match to protein family HMM PF00849; match to protein family HMM TIGR00093 YP_181522.1 identified by similarity to OMNI:NTL02MA2606 YP_181523.1 identified by similarity to SP:P39761; match to protein family HMM TIGR01178 YP_181524.1 identified by similarity to SP:P37472; match to protein family HMM TIGR01203 YP_181526.1 identified by similarity to OMNI:TM0389 YP_181527.1 identified by similarity to SP:P75774 YP_181528.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_181529.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_181534.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_181535.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_181536.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_181537.1 identified by similarity to OMNI:CT0198 YP_181541.1 identified by similarity to OMNI:NTL01LI0916 YP_181542.1 identified by similarity to OMNI:NTL01CG1421 YP_181544.1 identified by match to protein family HMM PF01458 YP_181545.1 identified by similarity to OMNI:NTL02MA3577 YP_181546.1 identified by similarity to SP:P80305 YP_181548.1 identified by similarity to SP:P21884 YP_181549.1 identified by similarity to SP:Q9UX79; match to protein family HMM PF01951 YP_181550.1 identified by similarity to OMNI:AF0862; match to protein family HMM PF01139 YP_181552.1 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA YP_181553.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_181554.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_181555.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_181557.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_181558.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_181559.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_181560.1 identified by match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_181561.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_181562.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_181563.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_181565.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_181566.1 identified by similarity to SP:O58058; match to protein family HMM TIGR01162 YP_181567.1 identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928 YP_181568.1 identified by similarity to SP:Q59566; match to protein family HMM PF01259; match to protein family HMM TIGR00081 YP_181569.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_181570.1 identified by match to protein family HMM TIGR01141 YP_181571.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_181574.1 identified by similarity to OMNI:NTL01PF1533 YP_181575.1 identified by match to protein family HMM PF01145 YP_181576.1 identified by similarity to GP:773349; match to protein family HMM PF03099; match to protein family HMM TIGR00121 YP_181577.1 identified by similarity to OMNI:NTL01MM0209 YP_181578.1 identified by similarity to GP:3688825 YP_181579.1 identified by similarity to GP:3688826 YP_181583.1 identified by similarity to OMNI:NTL02SC5631 YP_181584.1 identified by match to protein family HMM PF06969; match to protein family HMM TIGR00539 YP_181585.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_181586.1 identified by similarity to GP:3005967 YP_181587.1 identified by similarity to GP:3005968 YP_181588.1 identified by similarity to GP:3005969 YP_181589.1 identified by similarity to GP:14250933 YP_181590.1 identified by similarity to GP:14250934 YP_181591.1 identified by similarity to GP:1032477 YP_181592.1 identified by similarity to SP:P76440 YP_181593.1 identified by similarity to GP:3005971 YP_181594.1 identified by similarity to GP:3005972 YP_181596.1 identified by match to protein family HMM TIGR00038 YP_181601.1 identified by similarity to GP:27462922 YP_181602.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_181603.1 identified by similarity to GP:10835922 YP_181604.1 identified by similarity to GP:6690145 YP_181605.1 identified by match to protein family HMM PF01844 YP_181607.1 identified by similarity to GP:601880 YP_181608.1 identified by match to protein family HMM TIGR01764 YP_181610.1 identified by similarity to SP:P31080; match to protein family HMM PF00717 YP_181612.1 identified by similarity to SP:Q08346 YP_181618.1 identified by similarity to OMNI:NTL03SA2242 YP_181628.1 identified by similarity to OMNI:NTL03PA00694 YP_181629.1 identified by match to protein family HMM TIGR01612 YP_181631.1 identified by similarity to SP:P55888 YP_181632.1 identified by similarity to GP:29605703 YP_181633.1 identified by similarity to SP:P37310 YP_181636.1 identified by similarity to SP:P24828; match to protein family HMM PF02073 YP_181638.1 identified by similarity to OMNI:NTL01PA0908 YP_181641.1 identified by similarity to OMNI:NTL02MA0630 YP_181644.1 identified by similarity to OMNI:MJ1526 YP_181646.1 identified by similarity to OMNI:NTL01SS00401; match to protein family HMM PF01837 YP_181647.1 identified by similarity to SP:P24559; match to protein family HMM TIGR01420 YP_181648.1 identified by similarity to SP:O68852; match to protein family HMM PF00507 YP_181649.1 identified by match to protein family HMM TIGR01957 YP_181650.1 identified by similarity to SP:O84971 YP_181651.1 identified by match to protein family HMM TIGR01962 YP_181652.1 identified by similarity to SP:P33603 YP_181653.1 identified by similarity to SP:Q00236 YP_181654.1 identified by similarity to SP:P50975 YP_181655.1 identified by similarity to SP:P50940 YP_181656.1 identified by match to protein family HMM TIGR01974 YP_181657.1 identified by match to protein family HMM TIGR01972 YP_181658.1 identified by match to protein family HMM TIGR01770 YP_181659.1 identified by match to protein family HMM TIGR00010 YP_181660.1 identified by match to protein family HMM TIGR01083 YP_181661.1 identified by match to protein family HMM TIGR00313 YP_181662.1 identified by similarity to SP:P76084; match to protein family HMM TIGR00369 YP_181663.1 identified by similarity to SP:P22730 YP_181666.1 identified by similarity to SP:P21630 YP_181669.1 identified by similarity to SP:P22729 YP_181670.1 identified by similarity to SP:P08340 YP_181672.1 identified by similarity to SP:O07835 YP_181673.1 Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. YP_181675.1 identified by similarity to OMNI:NTL01SS00193 YP_181676.1 identified by similarity to SP:P05340; match to protein family HMM PF01592 YP_181677.1 identified by similarity to OMNI:TM0315 YP_181678.1 identified by similarity to SP:P37279; match to protein family HMM PF00403; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_181680.1 identified by similarity to SP:P49944 YP_181681.1 identified by similarity to SP:Q03300; match to protein family HMM PF02777 YP_181682.1 identified by match to protein family HMM PF01713 YP_181684.1 identified by similarity to OMNI:NTL01MM1085; match to protein family HMM PF01995 YP_181685.1 identified by match to protein family HMM TIGR00089; match to protein family HMM TIGR01579 YP_181686.1 identified by similarity to SP:P73283; match to protein family HMM PF02801 YP_181687.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_181689.1 identified by similarity to SP:O34752; match to protein family HMM TIGR00544 YP_181690.1 identified by similarity to GP:29608270 YP_181691.1 identified by similarity to OMNI:NTL01CA0729; match to protein family HMM PF04456 YP_181692.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_181693.1 identified by similarity to SP:P50849 YP_181694.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_181695.1 identified by similarity to SP:Q04797; match to protein family HMM TIGR01296 YP_181696.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_181697.1 identified by similarity to SP:P13249 YP_181698.1 identified by similarity to OMNI:MT0141 YP_181699.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_181700.1 identified by similarity to GP:10442119 YP_181701.1 identified by similarity to OMNI:NTL01ML0454 YP_181702.1 identified by match to protein family HMM PF01658 YP_181704.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_181705.1 identified by similarity to SP:P09170; match to protein family HMM PF02033; match to protein family HMM TIGR00082 YP_181706.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_181707.1 identified by similarity to OMNI:NTL01TT1300; match to protein family HMM PF04296 YP_181708.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_181709.1 identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368 YP_181710.1 identified by similarity to OMNI:NTL01BS1205 YP_181711.1 identified by similarity to GP:29896471 YP_181712.1 identified by similarity to OMNI:NMB0465; match to protein family HMM PF04367 YP_181713.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_181714.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_181715.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_181716.1 binds directly to 23S ribosomal RNA YP_181717.1 identified by similarity to SP:Q06795; match to protein family HMM PF02357; match to protein family HMM TIGR00922 YP_181718.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_181719.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_181720.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_181721.1 identified by similarity to OMNI:NTL01PA1525 YP_181722.1 identified by similarity to OMNI:NTL01CG0396 YP_181727.1 identified by match to protein family HMM TIGR00412 YP_181728.1 identified by similarity to OMNI:SP1661 YP_181730.1 identified by similarity to GP:28809963 YP_181735.1 identified by similarity to SP:P76085 YP_181736.1 identified by match to protein family HMM TIGR00229; match to protein family HMM TIGR01612 YP_181738.1 identified by similarity to OMNI:NTL02LI3523 YP_181741.1 identified by similarity to SP:P51833; match to protein family HMM PF00035 YP_181743.1 catalyzes the hydrolysis of acylphosphate YP_181746.1 identified by similarity to SP:P27888 YP_181747.1 identified by similarity to OMNI:PSPTO0976 YP_181748.1 identified by match to protein family HMM TIGR00762 YP_181749.1 identified by similarity to SP:P29212 YP_181751.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_181752.1 identified by similarity to SP:P09376 YP_181753.1 identified by similarity to SP:O34358; similarity to SP:P09376 YP_181754.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_181755.1 identified by similarity to SP:Q01620 YP_181757.1 identified by match to protein family HMM PF01011 YP_181758.1 identified by similarity to SP:P25814; match to protein family HMM PF00825; match to protein family HMM TIGR00188 YP_181759.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_181760.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_181761.1 identified by match to protein family HMM TIGR00621 YP_181762.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_181767.1 identified by match to protein family HMM TIGR00004 YP_181768.1 identified by similarity to SP:Q48319 YP_181770.1 identified by match to protein family HMM TIGR00634 YP_181772.1 identified by similarity to OMNI:NTL01TT0716 YP_181774.1 identified by similarity to GP:5764627 YP_181776.1 identified by similarity to OMNI:CT0598; match to protein family HMM PF07521 YP_181779.1 identified by similarity to OMNI:NTL02MA1586; match to protein family HMM TIGR00229 YP_181780.1 identified by match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_181785.1 identified by match to protein family HMM PF01183 YP_181786.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593 YP_181793.1 identified by match to protein family HMM PF05017; match to protein family HMM TIGR01760 YP_181794.1 identified by similarity to OMNI:NTL01LI2553 YP_181795.1 identified by match to protein family HMM TIGR01603 YP_181796.1 identified by similarity to OMNI:NTL01LL1060 YP_181797.1 identified by similarity to OMNI:NTL01LL1059 YP_181798.1 identified by match to protein family HMM TIGR01563 YP_181800.1 identified by match to protein family HMM TIGR01554 YP_181802.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_181804.1 identified by similarity to GP:3482867 YP_181806.1 identified by similarity to GP:3482866 YP_181812.1 identified by similarity to OMNI:EF0329 YP_181813.1 identified by similarity to GP:563258; match to protein family HMM PF05272 YP_181816.1 identified by similarity to GP:18920552 YP_181817.1 identified by similarity to OMNI:EF0319 YP_181820.1 identified by similarity to GP:29341850 YP_181822.1 identified by similarity to GP:29341852 YP_181823.1 identified by similarity to OMNI:NTL03SP0465 YP_181824.1 identified by match to protein family HMM TIGR01612 YP_181825.1 identified by similarity to GP:26111617 YP_181826.1 identified by similarity to SP:Q9PRB1; match to protein family HMM PF04326 YP_181827.1 identified by similarity to SP:P40814 YP_181828.1 identified by similarity to OMNI:NTL01MM2811 YP_181829.1 identified by similarity to SP:P08764 YP_181833.1 identified by similarity to OMNI:SAG2033 YP_181835.1 identified by similarity to SP:Q02169; match to protein family HMM TIGR00172 YP_181836.1 identified by similarity to OMNI:NTL02MA2188 YP_181837.1 identified by similarity to SP:Q03638; match to protein family HMM TIGR00552 YP_181838.1 identified by similarity to SP:Q59812; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 YP_181840.1 identified by similarity to SP:Q07429; match to protein family HMM TIGR00836 YP_181841.1 identified by similarity to SP:Q05943 YP_181842.1 identified by similarity to OMNI:TM0394 YP_181844.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_181845.1 identified by similarity to SP:O29310; match to protein family HMM PF00310 YP_181847.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_181850.1 identified by match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_181853.1 identified by match to protein family HMM TIGR00380 YP_181854.1 identified by similarity to GP:11513599 YP_181856.1 identified by match to protein family HMM PF01522 YP_181858.1 identified by similarity to OMNI:NTL01MM2775 YP_181861.1 identified by similarity to SP:P06975 YP_181863.1 identified by similarity to OMNI:CT1099 YP_181864.1 identified by similarity to SP:P07324 YP_181866.1 identified by match to protein family HMM PF00148 YP_181867.1 identified by match to protein family HMM TIGR01283 YP_181868.1 identified by match to protein family HMM TIGR01286 YP_181869.1 identified by similarity to SP:P00467; match to protein family HMM TIGR01282; match to protein family HMM TIGR01862 YP_181870.1 identified by match to protein family HMM PF00543 YP_181871.1 identified by similarity to SP:Q50786 YP_181872.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex YP_181873.1 identified by match to protein family HMM PF03459 YP_181874.1 identified by similarity to SP:P09834; similarity to GP:3955199 YP_181875.1 identified by similarity to SP:P37329; match to protein family HMM TIGR01256 YP_181877.1 identified by similarity to GP:28271879 YP_181879.1 identified by similarity to OMNI:MJ1613 YP_181885.1 identified by similarity to GP:3002555; similarity to GP:5531941; match to protein family HMM TIGR01409 YP_181887.1 identified by match to protein family HMM PF02663 YP_181888.1 identified by match to protein family HMM PF01497 YP_181889.1 identified by similarity to GP:17063216 YP_181891.1 identified by similarity to OMNI:NTL02MA1808 YP_181893.1 identified by similarity to OMNI:NTL01TT2326 YP_181894.1 identified by similarity to OMNI:NTL03CP0527 YP_181900.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_181901.1 identified by similarity to SP:P17620; match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506 YP_181902.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_181903.1 identified by match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326 YP_181904.1 identified by match to protein family HMM PF04402 YP_181905.1 identified by similarity to SP:P72365; match to protein family HMM PF00461 YP_181906.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_181907.1 identified by similarity to OMNI:TM0646 YP_181908.1 identified by similarity to SP:P14160; match to protein family HMM PF01119; match to protein family HMM PF02518; match to protein family HMM TIGR00585 YP_181909.1 identified by similarity to SP:P56255; match to protein family HMM TIGR01369 YP_181911.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_181912.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_181913.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_181914.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_181915.1 identified by similarity to SP:P25994; match to protein family HMM TIGR01369 YP_181916.1 identified by similarity to SP:P25983 YP_181917.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_181918.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_181919.1 identified by similarity to SP:P08499; match to protein family HMM PF00742 YP_181920.1 identified by similarity to SP:P24327 YP_181921.1 identified by similarity to OMNI:NTL01TT0055 YP_181922.1 identified by similarity to SP:P27095 YP_181923.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_181924.1 identified by match to protein family HMM TIGR00536 YP_181925.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_181928.1 identified by similarity to SP:P21891 YP_181929.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_181930.1 identified by similarity to OMNI:NTL01MM3311 YP_181931.1 identified by similarity to OMNI:NTL02YP4055; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_181932.1 This protein performs the mismatch recognition step during the DNA repair process YP_181935.1 identified by similarity to SP:Q45132 YP_181936.1 identified by match to protein family HMM PF01557 YP_181937.1 identified by similarity to GB:AAA71929.1 YP_181938.1 identified by similarity to OMNI:NTL01TT0264; match to protein family HMM PF01950 YP_181939.1 identified by match to protein family HMM TIGR00042 YP_181940.1 identified by similarity to SP:P05649; match to protein family HMM TIGR00663 YP_181943.1 identified by similarity to GP:22652039 YP_181948.1 identified by similarity to OMNI:NTL02LI2731 YP_181950.1 identified by similarity to SP:P37051; match to protein family HMM TIGR00655 YP_181953.1 identified by similarity to SP:P87051 YP_181954.1 identified by match to protein family HMM PF01625; match to protein family HMM TIGR00401 YP_181957.1 identified by similarity to GP:28806015 YP_181962.1 identified by similarity to GP:11493843 YP_181967.1 identified by similarity to SP:P24559; match to protein family HMM TIGR01420 YP_181968.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_181969.1 identified by match to protein family HMM TIGR00761 YP_181970.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_181972.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_181973.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_181974.1 required for 70S ribosome assembly YP_181976.1 identified by similarity to GP:28202560; match to protein family HMM TIGR00762 YP_181977.1 identified by similarity to GP:29895885; match to protein family HMM TIGR00762 YP_181978.1 identified by similarity to SP:P70945; match to protein family HMM TIGR00762 YP_181979.1 identified by similarity to GP:28202560; match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_181980.1 catalyzes branch migration in Holliday junction intermediates YP_181982.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_181983.1 identified by similarity to GB:CAA22404.1 YP_181984.1 identified by similarity to SP:P16657 YP_181986.1 identified by similarity to GP:28203367 YP_181987.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_181988.1 identified by similarity to SP:P71019; match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_181989.1 identified by match to protein family HMM TIGR01830 YP_181990.1 identified by similarity to SP:P04381; match to protein family HMM PF01029; match to protein family HMM TIGR01951 YP_181991.1 carries the fatty acid chain in fatty acid biosynthesis YP_181992.1 identified by similarity to OMNI:CT1903 YP_181993.1 identified by match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM TIGR00580 YP_181994.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_181997.1 identified by similarity to SP:O34358 YP_181998.1 identified by similarity to SP:P09376; match to protein family HMM PF00089 YP_181999.1 identified by similarity to SP:P32184 YP_182000.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_182001.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_182002.1 identified by match to protein family HMM PF00293 YP_182003.1 identified by match to protein family HMM TIGR00199 YP_182004.1 identified by similarity to SP:Q8EBY9 YP_182005.1 identified by match to protein family HMM TIGR00229 YP_182006.1 identified by match to protein family HMM TIGR01764 YP_182008.1 identified by similarity to OMNI:NTL03CP0999 YP_182010.1 identified by match to protein family HMM TIGR00231 YP_182011.1 identified by similarity to OMNI:NTL01RS0547 YP_182013.1 identified by similarity to GP:1477486 YP_182015.1 identified by match to protein family HMM PF02469 YP_182017.1 identified by similarity to GP:2959339 YP_182019.1 identified by similarity to OMNI:NTL01ATC0354; match to protein family HMM PF07411 YP_182022.1 identified by similarity to OMNI:NTL01MM3154 YP_182025.1 identified by match to protein family HMM PF01871; match to protein family HMM PF01875; match to protein family HMM TIGR00296 YP_182028.1 identified by similarity to GP:6723399 YP_182029.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_182031.1 identified by similarity to OMNI:NTL01BH0316 YP_182032.1 identified by similarity to GP:29897287 YP_182034.1 identified by similarity to GP:28373853; match to protein family HMM TIGR00152 YP_182035.1 identified by similarity to OMNI:DR1980 YP_182036.1 identified by match to protein family HMM PF00829 YP_182037.1 involved in the peptidyltransferase reaction during translation YP_182038.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_182039.1 identified by similarity to OMNI:NTL01TT0128 YP_182040.1 identified by similarity to SP:P06989; match to protein family HMM PF01502 YP_182041.1 identified by similarity to OMNI:NTL02MA1744 YP_182042.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_182043.1 identified by similarity to OMNI:NTL01MM3337 YP_182044.1 identified by similarity to OMNI:NTL01PA0538 YP_182045.1 identified by match to protein family HMM PF02686; match to protein family HMM TIGR00135 YP_182046.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_182048.1 identified by similarity to OMNI:NTL01MM0928 YP_182049.1 identified by similarity to OMNI:MJ0272 YP_182050.1 identified by similarity to OMNI:NTL02MA1555 YP_182051.1 identified by similarity to OMNI:NTL01TT2342 YP_182052.1 identified by similarity to SP:O07920 YP_182053.1 identified by similarity to SP:P23034 YP_182054.1 identified by match to protein family HMM TIGR00233 YP_182055.1 identified by similarity to SP:P22565; match to protein family HMM PF02401; match to protein family HMM TIGR00216 YP_182056.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_182059.1 identified by similarity to SP:Q45585 YP_182060.1 identified by match to protein family HMM TIGR01764 YP_182061.1 identified by similarity to SP:P13800 YP_182062.1 identified by similarity to GP:4139237; match to protein family HMM PF05157 YP_182063.1 identified by similarity to SP:P45793 YP_182064.1 identified by similarity to SP:P15749 YP_182065.1 identified by similarity to OMNI:NTL01XA0698 YP_182069.1 identified by similarity to OMNI:NTL03PA05045 YP_182070.1 identified by similarity to SP:P24559; match to protein family HMM TIGR01420 YP_182071.1 identified by similarity to SP:P45773 YP_182073.1 identified by similarity to SP:P15378 YP_182074.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; functions in mannosylglycerate biosynthesis YP_182075.1 identified by similarity to GP:1100876 YP_182076.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_182079.1 identified by match to protein family HMM PF04055 YP_182081.1 identified by similarity to SP:Q9KD56; match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_182083.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_182084.1 identified by similarity to SP:P18274; match to protein family HMM PF01258 YP_182085.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_182086.1 identified by match to protein family HMM TIGR00005 YP_182087.1 identified by similarity to OMNI:AF1663 YP_182092.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; match to protein family HMM TIGR00277 YP_182093.1 identified by match to protein family HMM TIGR00078 YP_182094.1 identified by match to protein family HMM TIGR00739 YP_182095.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_182096.1 identified by similarity to OMNI:CC0674 YP_182097.1 identified by similarity to OMNI:SP0830 YP_182098.1 identified by match to protein family HMM PF01149; match to protein family HMM TIGR00577 YP_182100.1 identified by similarity to SP:O08307; match to protein family HMM PF01367; match to protein family HMM PF01612; match to protein family HMM TIGR00593 YP_182101.1 identified by match to protein family HMM PF00581 YP_182103.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_182104.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_182105.1 identified by similarity to SP:Q8R9J2 YP_182106.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_182107.1 identified by similarity to SP:P08622; match to protein family HMM PF01556 YP_182108.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_182109.1 identified by similarity to SP:P15874 YP_182110.1 identified by similarity to SP:P25499; match to protein family HMM PF01628 YP_182111.1 identified by similarity to OMNI:TM0207 YP_182112.1 identified by similarity to GP:28058107 YP_182113.1 identified by similarity to OMNI:NTL01HS00937 YP_182116.1 identified by similarity to GP:5305639; match to protein family HMM PF02012 YP_182117.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_182118.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_182119.1 identified by similarity to SP:P08622; match to protein family HMM PF00226 YP_182120.1 identified by similarity to SP:P40183 YP_182121.1 identified by similarity to SP:P37571; match to protein family HMM PF00004; match to protein family HMM PF02861 YP_182122.1 identified by similarity to GP:10198137 YP_182123.1 identified by similarity to SP:P00497; match to protein family HMM TIGR01134 YP_182124.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_182125.1 involved in de novo purine biosynthesis YP_182126.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_182127.1 identified by similarity to SP:O29774; match to protein family HMM TIGR01439 YP_182128.1 in Rhodopseudomonas palustris this protein confers resistance to arsenite; catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine YP_182130.1 identified by match to protein family HMM PF00300 YP_182131.1 identified by match to protein family HMM PF01435 YP_182132.1 identified by similarity to OMNI:NTL01TT0849 YP_182133.1 identified by match to protein family HMM PF03471 YP_182134.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_182135.1 identified by similarity to SP:O50322 YP_182136.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_182137.1 identified by match to protein family HMM PF00675 YP_182138.1 identified by similarity to SP:P24189; match to protein family HMM PF01155; match to protein family HMM TIGR00100 YP_182139.1 identified by similarity to SP:Q43949; match to protein family HMM PF01495; match to protein family HMM TIGR00073 YP_182140.1 identified by similarity to SP:O07451; match to protein family HMM TIGR00143 YP_182141.1 identified by similarity to GP:15430693; match to protein family HMM TIGR00074 YP_182142.1 identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_182143.1 identified by similarity to SP:P40595 YP_182148.1 identified by similarity to OMNI:EF1643 YP_182149.1 identified by match to protein family HMM TIGR01764 YP_182152.1 identified by match to protein family HMM TIGR00427 YP_182153.1 identified by similarity to OMNI:NTL02ML0889 YP_182155.1 identified by similarity to OMNI:NTL03CP0412 YP_182157.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_182159.1 identified by similarity to OMNI:NTL01MM1820; match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_182161.1 identified by similarity to SP:P39147 YP_182162.1 identified by match to protein family HMM TIGR00741 YP_182163.1 identified by match to protein family HMM TIGR00589 YP_182165.1 identified by match to protein family HMM TIGR00608 YP_182167.1 identified by match to protein family HMM TIGR00594; match to protein family HMM TIGR01369 YP_182168.1 identified by similarity to OMNI:NTL01TT1854; match to protein family HMM TIGR01906 YP_182171.1 identified by similarity to OMNI:TM1186 YP_182172.1 identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643 YP_182176.1 identified by match to protein family HMM TIGR01764 YP_182181.1 identified by similarity to PIR:A39128; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00564 YP_182182.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_182183.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_182184.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_182185.1 identified by match to protein family HMM PF00697 YP_182186.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_182187.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_182188.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_182189.1 identified by match to protein family HMM PF02511 YP_182191.1 identified by match to protein family HMM TIGR01727 YP_182194.1 identified by match to protein family HMM PF00496 YP_182195.1 identified by similarity to OMNI:NTL02MA3829 YP_182196.1 identified by similarity to GB:AAK04868.1 YP_182198.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_182199.1 identified by similarity to OMNI:NTL02MA2934 YP_182200.1 identified by similarity to OMNI:NTL02MA1100 YP_182201.1 identified by similarity to SP:P18086 YP_182202.1 identified by similarity to OMNI:NTL01MM3272 YP_182203.1 identified by similarity to SP:P33650; match to protein family HMM TIGR00231 YP_182204.1 identified by similarity to OMNI:NTL01TT0221 YP_182205.1 identified by similarity to GP:22776586 YP_182206.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_182207.1 identified by similarity to SP:P24580; match to protein family HMM PF01527 YP_182208.1 identified by similarity to OMNI:NTL01SS02515 YP_182213.1 identified by similarity to OMNI:NTL01CA3433 YP_182214.1 identified by similarity to GP:12642549 YP_182215.1 identified by similarity to GB:AAK00280.1 YP_182216.1 identified by similarity to GP:27228279 YP_182217.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182219.1 identified by similarity to GP:27228279 YP_182220.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182225.1 identified by similarity to GP:27228279 YP_182226.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182227.1 identified by similarity to OMNI:NTL01NS0727; match to protein family HMM TIGR00229 YP_182230.1 identified by match to protein family HMM PF02579 YP_182232.1 identified by similarity to GP:27462922 YP_182233.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182234.1 identified by similarity to GB:BAC71817.1 YP_182235.1 identified by similarity to GP:27228279 YP_182236.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182237.1 identified by similarity to OMNI:NTL02MA1116; match to protein family HMM TIGR00229 YP_182238.1 identified by similarity to SP:P21866 YP_182242.1 identified by similarity to GP:27228279 YP_182243.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182245.1 identified by similarity to SP:P07022; match to protein family HMM PF00800 YP_182246.1 identified by similarity to OMNI:NTL01TE2176 YP_182248.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_182253.1 identified by similarity to OMNI:MJ1613 YP_182255.1 identified by similarity to GP:27228279 YP_182256.1 identified by similarity to GP:8163916; match to protein family HMM TIGR01409 YP_182257.1 identified by match to protein family HMM TIGR00229 YP_182258.1 identified by similarity to SP:P54662 YP_182267.1 identified by similarity to SP:P77668 YP_182268.1 identified by similarity to SP:P77329; match to protein family HMM PF00346 YP_182269.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_182270.1 identified by similarity to OMNI:NTL01MM1061 YP_182271.1 identified by similarity to SP:P77858 YP_182272.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_182273.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_182276.1 identified by similarity to OMNI:NTL01NS1411; match to protein family HMM PF00924 YP_182279.1 identified by similarity to OMNI:AF1697 YP_182281.1 identified by similarity to GP:27361669 YP_182284.1 identified by match to protein family HMM TIGR01172 YP_182285.1 identified by similarity to SP:P36654; match to protein family HMM PF03091 YP_182286.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_182287.1 identified by similarity to SP:O86169 YP_182290.1 identified by similarity to GP:2177178; match to protein family HMM PF02424; match to protein family HMM TIGR01409 YP_182291.1 identified by similarity to GP:7710206 YP_182293.1 identified by similarity to GP:7710206 YP_182294.1 identified by similarity to SP:P27857; match to protein family HMM TIGR00945 YP_182297.1 identified by match to protein family HMM TIGR01411 YP_182298.1 identified by similarity to SP:P28822; match to protein family HMM TIGR01496 YP_182299.1 identified by match to protein family HMM TIGR01498 YP_182302.1 identified by match to protein family HMM PF02631 YP_182303.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_182304.1 identified by similarity to OMNI:NTL01BH2379; match to protein family HMM PF00149; match to protein family HMM TIGR00282 YP_182306.1 identified by similarity to SP:Q9RSV1 YP_182308.1 identified by similarity to SP:P28634; match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_182309.1 identified by similarity to SP:Q44290 YP_182310.1 identified by match to protein family HMM PF01230 YP_182311.1 identified by match to protein family HMM TIGR01439 YP_182312.1 identified by similarity to SP:O29392 YP_182314.1 identified by similarity to OMNI:NTL01TT2024 YP_182317.1 identified by similarity to OMNI:CT0707; match to protein family HMM PF03479 YP_182318.1 identified by similarity to SP:P00273; match to protein family HMM TIGR00319 YP_182320.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_182322.1 identified by similarity to OMNI:NTL01PA1700 YP_182323.1 identified by similarity to OMNI:NTL01TT0848 YP_182324.1 identified by similarity to SP:P05653; match to protein family HMM PF03989; match to protein family HMM TIGR01063 YP_182325.1 identified by match to protein family HMM PF00515 YP_182326.1 identified by match to protein family HMM PF01106 YP_182327.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_182329.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM YP_182330.1 identified by match to protein family HMM TIGR00444 YP_182332.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_182333.1 identified by similarity to SP:P31080 YP_182334.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_182335.1 identified by match to protein family HMM TIGR00460