-- dump date 20140619_060254 -- class Genbank::CDS -- table cds_note -- id note YP_593982.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_593911.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_593903.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_593891.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_593883.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_593870.1 catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a YP_593865.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 YP_594353.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_594352.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_594250.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_594242.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_594238.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_594237.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_594220.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_594199.1 catalyzes the interconversion of D-xylose to D-xylulose YP_594135.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_594124.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_594120.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_594119.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_594118.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_594117.1 Plays a crucial role on both purine and pyrimidine metabolism YP_594114.1 Catalyzes the deamination of guanine YP_594088.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_594027.1 activates fatty acids by binding to coenzyme A YP_594016.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_594015.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_603474.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_603476.1 KEGG: dra:DR0001 DNA polymerase III, beta subunit, ev=1e-169, 87% identity; TIGRFAM: DNA polymerase III, beta subunit: (3.8e-56); PFAM: DNA polymerase III, beta chain: (1.1e-18) YP_603477.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_603478.1 PFAM: pyruvate kinase: (9.6e-166); KEGG: dra:DR2635 pyruvate kinase, ev=0.0, 86% identity YP_603479.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_603480.1 PFAM: MOSC: (2.7e-30); KEGG: dra:DR0273 hypothetical protein, ev=1e-77, 77% identity YP_603481.1 PFAM: Uncharacterized protein UPF0114: (1.5e-38); KEGG: dra:DR0275 hypothetical protein, ev=2e-58, 65% identity YP_603482.1 PFAM: protein of unknown function DUF633: (7e-65); KEGG: dra:DR0276 hypothetical protein, ev=2e-82, 69% identity YP_603483.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_603484.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes: (2e-197) DegT/DnrJ/EryC1/StrS aminotransferase: (0.00017) aromatic amino acid beta-eliminating lyase/threonine aldolase: (0.0014); KEGG: dra:DR0921 methionine-gamma-lyase, ev=1e-158, 73% identity YP_603485.1 PFAM: protein of unknown function UPF0126: (1.4e-32); KEGG: dra:DR2368 hypothetical protein, ev=9e-93, 79% identity YP_603486.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_603487.1 PFAM: transcriptional activator domain: (7e-05); KEGG: sth:STH810 transcriptional regulator, ev=1e-07, 27% identity YP_603489.1 PFAM: cytochrome c oxidase, subunit II: (1.1e-19); KEGG: gka:GK1547 cytochrome c oxidase (b(o/a)3-type) chain II, ev=2e-27, 39% identity YP_603490.1 PFAM: cytochrome c oxidase, subunit I: (2e-07); KEGG: ttj:TTHA1135 ba3-type cytochrome c oxidase polypeptide I, ev=1e-164, 52% identity YP_603491.1 PFAM: cytochrome c, class I: (6.9e-06); KEGG: dra:DR2095 C-type cytochrome, , ev=1e-15, 47% identity YP_603492.1 KEGG: dra:DR2285 A/G-specific adenine glycosylase, ev=1e-128, 67% identity; TIGRFAM: A/G-specific adenine glycosylase: (1.6e-127); PFAM: HhH-GPD: (7.5e-26); SMART: Iron-sulfur cluster loop: (2.2e-07) YP_603493.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_603494.1 PFAM: HRDC: (2.5e-18); KEGG: dra:DR2444 nucleic acid-binding protein, , HRDC family, ev=1e-141, 52% identity YP_603495.1 KEGG: dra:DR2591 hypothetical protein, ev=9e-41, 69% identity YP_603496.1 PFAM: ABC transporter related: (2.2e-48); SMART: ATPase: (5.8e-17); KEGG: dra:DR2590 iron transport system ATP-binding protein, ev=1e-101, 72% identity YP_603497.1 PFAM: transport system permease: (3.5e-105) ABC-3: (0.0013); KEGG: dra:DR2589 iron transport system permease, ev=1e-137, 79% identity YP_603498.1 PFAM: periplasmic binding protein: (4.1e-35); KEGG: dra:DR2588 iron transport system substrate-binding protein, ev=1e-122, 72% identity YP_603499.1 PFAM: phospholipid/glycerol acyltransferase: (3.5e-27); KEGG: dra:DR2587 hypothetical protein, ev=1e-77, 67% identity YP_603500.1 KEGG: dra:DR2586 hypothetical protein, ev=3e-20, 69% identity YP_603501.1 KEGG: dra:DR0017 hypothetical protein, ev=3e-53, 88% identity YP_603502.1 KEGG: dra:DR0018 hypothetical protein, ev=5e-53, 57% identity YP_603503.1 KEGG: dra:DR0019 hypothetical protein, ev=2e-69, 47% identity YP_603504.1 PFAM: ribonuclease II: (6e-51); KEGG: dra:DR0020 ribonuclease II family protein, ev=0.0, 77% identity YP_603505.1 KEGG: dra:DR0021 hypothetical protein, ev=2e-27, 69% identity YP_603506.1 PFAM: Porphyromonas-type peptidyl-arginine deiminase: (2.5e-180); KEGG: dra:DR2359 hypothetical protein, ev=1e-154, 72% identity YP_603507.1 KEGG: dra:DR2334 hypothetical protein, ev=1e-130, 62% identity YP_603508.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase: (4.5e-55); KEGG: dra:DR2535 hydrolase, , ev=1e-152, 86% identity YP_603509.1 KEGG: dra:DR2290 pseudouridylate synthase I, ev=3e-94, 68% identity; TIGRFAM: tRNA pseudouridine synthase A: (1.7e-62); PFAM: tRNA pseudouridine synthase: (1.4e-17) YP_603510.1 PFAM: Peptidoglycan-binding LysM: (7.4e-11) peptidase M23B: (4.3e-45); KEGG: dra:DR2291 cell wall glycyl-glycine endopeptidase, , ev=1e-53, 43% identity YP_603511.1 KEGG: dra:DR2292 hypothetical protein, ev=2e-14, 54% identity YP_603512.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_603513.1 PFAM: Alcohol dehydrogenase, zinc-binding: (5.1e-24) Alcohol dehydrogenase GroES-like: (1.4e-41); KEGG: ava:Ava_C0165 zinc-containing alcohol dehydrogenase superfamily, ev=1e-154, 65% identity YP_603514.1 PFAM: cyclase/dehydrase: (3.6e-23); KEGG: dra:DRA0006 hypothetical protein, ev=1e-46, 47% identity YP_603515.1 PFAM: response regulator receiver: (1.3e-21); KEGG: dra:DRA0139 response regulator, ev=8e-29, 45% identity YP_603516.1 KEGG: dra:DR0748a multisubunit Na+/H+ antiporter, MnhE subunit, ev=2e-19, 61% identity YP_603517.1 PFAM: Uncharacterized protein UPF0114: (2.3e-34); KEGG: dra:DR1879 hypothetical protein, ev=3e-91, 77% identity YP_603518.1 PFAM: polysaccharide deacetylase: (6.1e-25); KEGG: sco:SCO6050 lipoprotein, ev=5e-43, 41% identity YP_603519.1 KEGG: dra:DR0003 hypothetical protein, ev=1e-28, 39% identity YP_603520.1 PFAM: permease YjgP/YjgQ: (6.9e-47); KEGG: dra:DR2430 hypothetical protein, ev=1e-108, 56% identity YP_603521.1 PFAM: permease YjgP/YjgQ: (2.9e-60); KEGG: dra:DR2431 hypothetical protein, ev=1e-132, 69% identity YP_603522.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase: (8.8e-122) Methyltransferase type 11: (6.2e-16) Methyltransferase type 12: (1.3e-16); KEGG: dra:DR2187 cyclopropane-fatty-acyl-phospholipid synthase, , ev=1e-170, 66% identity YP_603523.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_603524.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_603525.1 PFAM: protein of unknown function UPF0079: (5.3e-30); KEGG: dra:DR2351 hypothetical protein, ev=3e-59, 79% identity YP_603526.1 KEGG: dra:DR2350 hypothetical protein, ev=3e-98, 52% identity YP_603527.1 KEGG: dra:DR2348 hypothetical protein, ev=1e-118, 47% identity YP_603528.1 PFAM: Roadblock/LC7: (3.3e-05); KEGG: dra:DR2347 hypothetical protein, ev=3e-61, 50% identity YP_603529.1 KEGG: dra:DR2346 glycine C-acetyltransferase, ev=0.0, 83% identity; TIGRFAM: Pyridoxal phosphate-dependent acyltransferase, : (1.3e-283); PFAM: aminotransferase, class I and II: (4.5e-74) YP_603530.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases: (2.3e-116); PFAM: RNA methylase: (0.0062) UbiE/COQ5 methyltransferase: (3.7e-48) Methyltransferase type 11: (5.7e-34) Methyltransferase type 12: (2.5e-18); KEGG: dra:DR2405 ubiquinone/menaquinone biosynthesis methyltransferase, ev=1e-104, 78% identity YP_603531.1 PFAM: glycosyl transferase, family 20: (1.8e-186); KEGG: sru:SRU_0569 trehalose-6-phosphate synthase domain, , ev=1e-117, 47% identity YP_603532.1 TIGRFAM: HAD-superfamily hydrolase subfamily IIB: (1.3e-12); PFAM: trehalose-phosphatase: (9.1e-34); KEGG: ttj:TTHA0479 trehalose-6-phosphate phosphatase, ev=3e-40, 48% identity YP_603533.1 KEGG: dra:DR2559 hypothetical protein, ev=3e-18, 54% identity YP_603534.1 PFAM: Phosphoglycerate mutase: (4e-46); KEGG: dra:DR0278 phosphoglycerate mutase, ev=1e-55, 58% identity YP_603535.1 TIGRFAM: amidophosphoribosyltransferase: (1.5e-253); PFAM: glutamine amidotransferase, class-II: (4.1e-24) phosphoribosyltransferase: (9.4e-13); KEGG: dra:DR0220 amidophosphoribosyltransferase, ev=0.0, 89% identity YP_603536.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_603537.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_603538.1 PFAM: phosphoribosylformylglycinamidine synthetase PurS: (5.7e-24); KEGG: dra:DR0224 hypothetical protein, ev=1e-29, 75% identity YP_603539.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_603540.1 TIGRFAM: modification methylase, HemK family: (2.7e-52); PFAM: methyltransferase small: (2.5e-09) ribosomal L11 methyltransferase: (0.005) Methyltransferase type 12: (2.2e-07); KEGG: dra:DR0245 hemK protein, ev=1e-101, 70% identity YP_603541.1 PFAM: single-stranded nucleic acid binding R3H: (2.7e-17); KEGG: dra:DR0246 Jag-related protein, ev=4e-79, 79% identity YP_603542.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type: (5.9e-49); KEGG: dra:DR0237 peptidyl-prolyl cis-trans isomerase, cyclophilin-type, ev=6e-85, 81% identity YP_603543.1 PFAM: peptidase M29, aminopeptidase II: (3.9e-190); KEGG: dra:DR0236 aminopeptidase, ev=1e-175, 73% identity YP_603544.1 PFAM: tRNA/rRNA methyltransferase (SpoU): (2.8e-40); KEGG: dra:DR0231 RNA methyltransferase, , ev=2e-71, 83% identity YP_603545.1 PFAM: MECDP-synthase: (1.5e-43); KEGG: dra:DR0230 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ev=1e-59, 77% identity YP_603546.1 PFAM: protein of unknown function UPF0029: (6.9e-60); KEGG: dra:DR2203 hypothetical protein, ev=1e-90, 81% identity YP_603547.1 PFAM: NUDIX hydrolase: (6.7e-22); KEGG: dra:DR2204 MutT/NUDIX family protein, ev=1e-80, 77% identity YP_603548.1 PFAM: DinB: (3.6e-41); KEGG: dra:DR2439 hypothetical protein, ev=1e-68, 68% identity YP_603549.1 PFAM: dihydrouridine synthase, DuS: (6.7e-83); KEGG: dra:DR2440 NifR3 protein, ev=1e-133, 74% identity YP_603550.1 PFAM: GCN5-related N-acetyltransferase: (4.1e-10); KEGG: dra:DR2441 hypothetical protein, ev=9e-53, 65% identity YP_603551.1 TIGRFAM: acetylglutamate kinase: (7.7e-70); PFAM: aspartate/glutamate/uridylate kinase: (8.9e-36); KEGG: dra:DR2442 N-acetylglutamate kinase, ev=1e-108, 81% identity YP_603552.1 KEGG: dra:DR2443 ribosomal protein N-acetyltransferase, , ev=2e-54, 60% identity YP_603553.1 KEGG: dra:DR0024 phosphoribosylaminoimidazole carboxylase ATPase subunit, ev=1e-159, 77% identity; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit: (9.4e-180); PFAM: ATP-dependent carboxylate-amine ligase-like, ATP-grasp: (1.9e-66) YP_603554.1 KEGG: dra:DR0023 phosphoribosylaminoimidazole carboxylase catalytic subunit, ev=3e-73, 81% identity; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit: (1.8e-93); PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase: (2.2e-80) YP_603555.1 KEGG: dra:DR0340 folylpolyglutamate synthase / dihydrofolate synthase, ev=1e-157, 73% identity; TIGRFAM: FolC bifunctional protein: (1.5e-116); PFAM: cytoplasmic peptidoglycan synthetases-like: (2.6e-06) Mur ligase, middle region: (8.4e-05) YP_603557.1 PFAM: protein of unknown function DUF326: (0.073); KEGG: tfu:Tfu_1443 hypothetical protein, ev=3e-37, 54% identity YP_603558.1 PFAM: protein of unknown function DUF305: (1e-20); KEGG: par:Psyc_0285 hypothetical protein, ev=4e-19, 33% identity YP_603559.1 PFAM: response regulator receiver: (1.1e-35) transcriptional regulatory protein-like: (4.8e-26); KEGG: ttj:TTHA1722 response regulator, ev=2e-75, 65% identity YP_603560.1 PFAM: ATP-binding region, ATPase-like: (3.8e-46) histidine kinase, HAMP region: (2.1e-15) histidine kinase A-like: (4.3e-12); KEGG: ttj:TTHA1723 sensor histidine kinase, ev=3e-95, 56% identity YP_603561.1 TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter: (1.6e-50) Copper ion-binding: (6.5e-09) ATPase, P type cation/copper-transporter: (2.6e-254) Heavy metal translocating P-type ATPase: (6.3e-254); PFAM: Haloacid dehalogenase-like hydrolase: (4.1e-41) Heavy metal transport/detoxification protein: (9.6e-13) E1-E2 ATPase-associated region: (1.1e-101); KEGG: dra:DR2453 cation-transporting ATPase, ev=0.0, 62% identity YP_603562.1 PFAM: Heavy metal transport/detoxification protein: (3.4e-16); KEGG: dra:DR2452 hypothetical protein, ev=6e-15, 61% identity YP_603563.1 PFAM: protein of unknown function DUF156: (8.9e-15); KEGG: dra:DR2449 hypothetical protein, ev=8e-32, 69% identity YP_603564.1 PFAM: CBS: (5.3e-24) protein of unknown function DUF21: (4.4e-63) transporter-associated region: (6e-18); KEGG: mlo:mlr2581 hemolysin, ev=3e-79, 40% identity YP_603565.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_603566.1 PFAM: Asparaginase/glutaminase: (1.5e-111); KEGG: dra:DR2353 L-asparaginase, ev=1e-135, 75% identity YP_603567.1 KEGG: dra:DR2612 DedA family protein, ev=2e-87, 73% identity YP_603568.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (1e-15); PFAM: Haloacid dehalogenase-like hydrolase: (2.6e-33); KEGG: dra:DR2613 hydrolase, CbbY/CbbZ/GpH/YieH family, ev=1e-100, 77% identity YP_603569.1 TIGRFAM: Twin-arginine translocation pathway signal: (0.015); KEGG: dra:DRB0118 dessication-associated protein, ev=1e-117, 75% identity YP_603570.1 PFAM: NAD-dependent epimerase/dehydratase: (0.002) short-chain dehydrogenase/reductase SDR: (5.2e-08); KEGG: dra:DR0543 oxidoreductase, short-chain dehydrogenase/reductase family, ev=6e-98, 79% identity YP_603571.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetases: (1e-239); PFAM: cytoplasmic peptidoglycan synthetase-like: (4.3e-17) cytoplasmic peptidoglycan synthetases-like: (6e-15) Mur ligase, middle region: (2.2e-70); KEGG: dra:DR0297 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase, ev=0.0, 80% identity YP_603572.1 PFAM: regulatory protein, ArsR: (2.7e-15); KEGG: dra:DRA0071 transcriptional repressor SmtB, ev=3e-35, 66% identity YP_603573.1 PFAM: deoxynucleoside kinase: (1.2e-39); KEGG: dra:DR0298 deoxyguanosine kinase/deoxyadenosine kinase subunit, ev=2e-99, 83% identity YP_603574.1 PFAM: deoxynucleoside kinase: (8.5e-18); KEGG: dra:DR0299 deoxyguanosine kinase/deoxyadenosine kinase subunit, ev=2e-74, 72% identity YP_603575.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap: (0.00016); SMART: PDZ/DHR/GLGF: (4.7e-09); KEGG: dra:DR0300 serine protease Do, , ev=1e-109, 74% identity YP_603576.1 KEGG: dra:DR0301 hypothetical protein, ev=4e-23, 72% identity YP_603577.1 PFAM: acyl-CoA dehydrogenase-like: (4.3e-22) Acyl-CoA dehydrogenase, type 2-like: (0.004); KEGG: dra:DR2361 acyl-CoA dehydrogenase, , ev=0.0, 82% identity YP_603578.1 PFAM: cyclic nucleotide-binding: (2.5e-29) regulatory protein, Crp: (4.9e-08); KEGG: dra:DR2362 transcriptional regulator, ev=1e-112, 89% identity YP_603579.1 PFAM: HhH-GPD: (3.2e-21); KEGG: dra:DR2584 DNA-3-methyladenine glycosidase II, , ev=2e-62, 61% identity YP_603580.1 KEGG: dvu:DVU0354 hypothetical protein, ev=3e-07, 30% identity YP_603581.1 PFAM: NAD-dependent epimerase/dehydratase: (0.0011) short-chain dehydrogenase/reductase SDR: (3.3e-13); KEGG: ttj:TTHA0461 dihydropteridine/dihydrofolate reductase, ev=3e-61, 55% identity YP_603582.1 PFAM: NUDIX hydrolase: (3.6e-25); KEGG: syn:sll1537 hypothetical protein, ev=2e-40, 59% identity YP_603583.1 PFAM: binding-protein-dependent transport systems inner membrane component: (2.9e-36) ABC transporter related: (3.5e-51); SMART: ATPase: (2.8e-21); KEGG: dra:DR0511 ABC transporter ATP-binding protein, ev=1e-177, 69% identity YP_603584.1 PFAM: protein of unknown function DUF6, transmembrane: (3.9e-30); KEGG: dra:DR0512 hypothetical protein, ev=1e-116, 71% identity YP_603586.1 PFAM: cyclase/dehydrase: (1.7e-33); KEGG: dra:DR2377 hypothetical protein, ev=1e-101, 86% identity YP_603587.1 KEGG: dra:DR2527 hypothetical protein, ev=3e-11, 30% identity YP_603589.1 PFAM: regulatory protein, TetR: (6.4e-16); KEGG: dra:DR2376 transcriptional regulator, TetR family, ev=2e-81, 78% identity YP_603590.1 PFAM: aminotransferase, class I and II: (1.2e-48); KEGG: dra:DR2461 histidinol-phosphate aminotransferase, ev=1e-137, 67% identity YP_603591.1 PFAM: protein of unknown function UPF0153: (2.6e-13); KEGG: dra:DR2460 hypothetical protein, ev=4e-39, 75% identity YP_603592.1 PFAM: Chromate transporter: (9.3e-24); KEGG: dra:DR2413 chromate transport protein, ev=1e-127, 62% identity YP_603593.1 PFAM: fatty acid desaturase, type 2: (8.6e-06); KEGG: bcz:BCZK2881 possible acyl-[acyl-carrier protein] desaturase, ev=3e-16, 27% identity YP_603594.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen: (1e-16) Redoxin: (5.3e-22); KEGG: dra:DR2242 thiol-specific antioxidant protein, , ev=4e-66, 80% identity YP_603596.1 PFAM: periplasmic binding protein: (6e-33); KEGG: dra:DRB0014 hemin transport system substrate-binding protein, ev=1e-129, 80% identity YP_603597.1 PFAM: transport system permease: (1e-116); KEGG: dra:DRB0015 hemin transport system permease, ev=1e-145, 76% identity YP_603598.1 with HmuTU is involved in the transport of hemin YP_603599.1 PFAM: Siderophore-interacting protein: (9.3e-46) FAD-binding 9, siderophore-interacting: (2.8e-24); KEGG: reu:Reut_B4272 siderophore-interacting protein, ev=4e-34, 40% identity YP_603600.1 PFAM: PhoU: (1.3e-29); KEGG: dra:DR2243 phosphate transport system regulatory protein PhoU, ev=1e-98, 86% identity YP_603601.1 PFAM: ATP-binding region, ATPase-like: (3.3e-24) histidine kinase A-like: (1.9e-11); KEGG: dra:DR2244 sensory transduction histidine kinase, ev=6e-99, 82% identity YP_603602.1 PFAM: response regulator receiver: (6.9e-31) transcriptional regulatory protein-like: (2.7e-25); KEGG: dra:DR2245 phosphate regulon transcriptional regulatory protein PhoB, ev=1e-104, 83% identity YP_603603.1 PFAM: Iojap-related protein: (1.9e-29); KEGG: dra:DR2580 hypothetical protein, ev=1e-49, 87% identity YP_603604.1 TIGRFAM: cell envelope-related function transcriptional attenuator common domain: (2.7e-73); PFAM: cell envelope-related transcriptional attenuator: (2e-49); KEGG: dra:DR2581 LytR/CspA/Psr family protein, ev=1e-142, 65% identity YP_603605.1 KEGG: dra:DR2582 hypothetical protein, ev=9e-71, 74% identity; TIGRFAM: conserved hypothetical protein: (9.5e-30); PFAM: metal-dependent phosphohydrolase, HD subdomain: (1.6e-20); SMART: Metal-dependent phosphohydrolase, HD region: (4.4e-14) YP_603606.1 PFAM: YbbR-like: (1.9e-08); KEGG: dra:DR0008 hypothetical protein, ev=1e-103, 59% identity YP_603607.1 PFAM: protein of unknown function DUF147: (9.8e-47); KEGG: dra:DR0007 hypothetical protein, ev=1e-107, 81% identity YP_603608.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_603609.1 KEGG: dra:DR0449 hypothetical protein, ev=4e-97, 74% identity YP_603610.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_603611.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase: (4.5e-244); PFAM: biotin/lipoyl attachment: (1.9e-24) catalytic domain of components of various dehydrogenase complexes: (2.3e-138) E3 binding: (5.3e-14); KEGG: dra:DR0083 2-oxoglutarate dehydrogenase, dihydrolipoamide succinyltransferase E2 component, ev=0.0, 78% identity YP_603612.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_603613.1 PFAM: transport-associated: (1.3e-17); KEGG: dra:DR0392 hypothetical protein, ev=2e-57, 43% identity YP_603614.1 KEGG: dra:DR1697 hypothetical protein, ev=2e-07, 42% identity YP_603615.1 PFAM: cytochrome P450: (1.9e-07); KEGG: dra:DRA0186 cytochrome P450, , ev=8e-92, 60% identity YP_603616.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_603617.1 PFAM: Enoyl-CoA hydratase/isomerase: (2e-31); KEGG: dra:DR0114 enoyl-CoA hydratase, , ev=1e-88, 67% identity YP_603618.1 PFAM: short-chain dehydrogenase/reductase SDR: (4.4e-10); KEGG: dra:DR0113 short chain dehydrogenase, ev=1e-137, 88% identity YP_603619.1 PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C: (8.7e-11); KEGG: dra:DR0176 D-alanyl-D-alanine carboxypeptidase, , ev=1e-151, 62% identity YP_603620.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_603621.1 TIGRFAM: crcB protein: (1.3e-20); PFAM: Camphor resistance CrcB protein: (1.9e-21); KEGG: dra:DR0185 integral membrane protein possibly involved in chromosome condensation, ev=4e-48, 80% identity YP_603622.1 PFAM: Mg2+ transporter protein, CorA-like: (2.8e-30); KEGG: dra:DR2399 hypothetical protein, ev=1e-89, 72% identity YP_603623.1 PFAM: TatD-related deoxyribonuclease: (1.3e-101) amidohydrolase 2: (0.0024); KEGG: dra:DR0146 deoxyribonuclease, ev=1e-115, 79% identity YP_603624.1 KEGG: dra:DR2318 hypothetical protein, ev=1e-53, 52% identity YP_603625.1 PFAM: OstA-like protein: (0.00028); KEGG: dra:DR2319 hypothetical protein, ev=1e-105, 68% identity YP_603626.1 PFAM: OstA-like protein: (0.0041); KEGG: dra:DR2320 hypothetical protein, ev=8e-91, 55% identity YP_603627.1 PFAM: UspA: (1.8e-19); KEGG: dra:DR2363 hypothetical protein, ev=4e-50, 64% identity YP_603628.1 PFAM: beta-lactamase-like: (3.5e-19) RNA-metabolising metallo-beta-lactamase: (2.3e-13); KEGG: dra:DRA0069 metallo-beta-lactamase family protein, ev=0.0, 72% identity YP_603629.1 PFAM: Exonuclease, RNase T and DNA polymerase III: (2.5e-10); SMART: Exonuclease: (3.5e-17); KEGG: sth:STH2271 DNA polymerase III-like protein, ev=1e-08, 31% identity YP_603630.1 KEGG: dra:DR2624 hypothetical protein, ev=1e-51, 60% identity YP_603631.1 PFAM: Rhodanese-like: (4e-09); KEGG: dra:DR2531 thiosulfate sulfurtransferase, ev=1e-125, 76% identity YP_603632.1 PFAM: aldo/keto reductase: (1.5e-110); KEGG: ecc:c0414 2,5-diketo-D-gluconic acid reductase A, ev=2e-95, 60% identity YP_603634.1 KEGG: dra:DR2462 hypothetical protein, ev=0.0, 80% identity; TIGRFAM: uncharacterized domain HDIG: (1.2e-25); PFAM: KH, type 1: (1.6e-07) metal-dependent phosphohydrolase, HD subdomain: (1.4e-26); SMART: Metal-dependent phosphohydrolase, HD region: (3.2e-16) KH: (1.8e-08) YP_603635.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_603636.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_603637.1 TIGRFAM: single-strand binding protein: (3.8e-37); PFAM: single-strand binding protein/Primosomal replication protein n: (2.6e-28); KEGG: dra:DR0100 single-stranded DNA-binding protein, ev=3e-71, 72% identity YP_603638.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_603639.1 KEGG: dra:DR2302 hypothetical protein, ev=2e-09, 60% identity YP_603640.1 PFAM: protein kinase: (6.1e-27); SMART: Tyrosine protein kinase: (4.3e-14) Serine/threonine protein kinase: (2.2e-42); KEGG: dra:DR1213 serine/threonine protein kinase, , ev=1e-100, 58% identity YP_603641.1 TIGRFAM: peptide chain release factor 2: (9.7e-140); PFAM: Class I peptide chain release factor: (2.8e-60) PCRF: (4.9e-32); KEGG: dra:DR0173 peptide chain release factor 2, ev=1e-180, 80% identity YP_603642.1 PFAM: transcription factor CarD: (3.2e-08); KEGG: ttj:TTHA0168 hypothetical protein, ev=2e-44, 53% identity YP_603643.1 PFAM: binding-protein-dependent transport systems inner membrane component: (4.4e-24); KEGG: hch:HCH_00159 ABC-type proline/glycine betaine transport system, permease component, ev=1e-47, 46% identity YP_603644.1 PFAM: ABC transporter related: (5.6e-68); SMART: ATPase: (3.9e-21); KEGG: sth:STH2630 glycine betaine/carnitine/choline ABC transporter ATP-binding protein, ev=5e-81, 52% identity YP_603645.1 PFAM: binding-protein-dependent transport systems inner membrane component: (4.5e-20); KEGG: ssn:SSO_2187 transport system permease, ev=2e-58, 41% identity YP_603646.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system: (3.9e-71); KEGG: cvi:CV4392 probable ABC transporter ev=7e-75, 51% identity YP_603647.1 PFAM: histone-like DNA-binding protein: (8.7e-27); KEGG: dra:DRA0065 DNA-binding protein HB, ev=6e-32, 64% identity YP_603648.1 PFAM: UBA/THIF-type NAD/FAD binding fold: (4.7e-61) MoeZ/MoeB: (1.9e-19); KEGG: dra:DR2269 molybdopterin biosynthesis MoeB, ev=1e-88, 70% identity YP_603649.1 PFAM: protein of unknown function DUF205: (2.4e-10); KEGG: dra:DR2270 hypothetical protein, ev=2e-60, 64% identity YP_603650.1 PFAM: Tetratricopeptide TPR_2: (5.6e-05); KEGG: dra:DR2271 hypothetical protein, ev=0.0, 58% identity YP_603651.1 KEGG: dra:DR2489 hypothetical protein, ev=0.0, 77% identity YP_603652.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_603653.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: (4e-87); PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase: (6.1e-61); KEGG: dra:DR2604 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, ev=2e-82, 76% identity YP_603654.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase: (4e-67); PFAM: flavoprotein: (7.8e-45); KEGG: dra:DR2603 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, ev=2e-80, 80% identity YP_603655.1 PFAM: regulatory protein, LuxR: (4.3e-19) response regulator receiver: (1.4e-33) Bacterio-opsin activator, HTH: (0.00024) sigma-70 region 4: (0.0019) Sigma-70, region 4 type 2: (0.00041); KEGG: dra:DRA0010 DNA-binding response regulator, ev=5e-77, 76% identity YP_603656.1 PFAM: ATP-binding region, ATPase-like: (1.2e-13) histidine kinase, dimerisation and phosphoacceptor region: (6.9e-26); KEGG: dra:DRA0009 hypothetical protein, ev=5e-87, 56% identity YP_603657.1 PFAM: ABC-2 type transporter: (0.0002); KEGG: dra:DRA0008 ABC-2 type transport system permease, ev=3e-88, 63% identity YP_603658.1 KEGG: xac:XAC4311 hypothetical protein, ev=4e-08, 35% identity YP_603659.1 PFAM: ABC transporter related: (5.4e-49); SMART: ATPase: (4e-15); KEGG: dra:DRA0007 ABC-2 type transport system ATP-binding protein, ev=1e-96, 67% identity YP_603660.1 KEGG: dra:DR0041 hypothetical protein, ev=5e-61, 59% identity YP_603661.1 PFAM: metallophosphoesterase: (0.00021); KEGG: dra:DR0042 hypothetical protein, ev=3e-91, 64% identity YP_603662.1 PFAM: regulatory proteins, IclR: (1.6e-06); KEGG: dra:DR1217 transcriptional regulator, IclR family, ev=1e-109, 83% identity YP_603663.1 KEGG: dra:DR2230 hypothetical protein, ev=2e-09, 54% identity YP_603664.1 PFAM: Nucleotidyl transferase: (7.5e-43); KEGG: ttj:TTHA0224 glucose-1-phosphate thymidylyltransferase, ev=3e-65, 43% identity YP_603665.1 PFAM: alpha/beta hydrolase fold: (7.9e-17); KEGG: dra:DR0654 proline iminopeptidase-related protein, ev=1e-129, 76% identity YP_603666.1 KEGG: dra:DR0780 hypothetical protein, ev=1e-31, 77% identity YP_603667.1 PFAM: response regulator receiver: (1.8e-38) transcriptional regulatory protein-like: (2.9e-23); KEGG: dra:DR0781 response regulator, OmpR/PhoB family, ev=1e-121, 95% identity YP_603668.1 PFAM: flavin reductase-like, FMN-binding: (6.2e-39); KEGG: dra:DR2459 oxidoreductase, , ev=1e-67, 76% identity YP_603669.1 KEGG: dra:DR2458 hypothetical protein, ev=1e-21, 62% identity YP_603670.1 PFAM: cobalamin synthesis protein, P47K: (7.5e-65) cobalamin synthesis CobW-like: (1.8e-29); KEGG: dra:DR2408 CobW protein, , ev=1e-140, 80% identity YP_603671.1 TIGRFAM: Phenylacetic acid degradation-related protein: (7.8e-20); PFAM: thioesterase superfamily: (3.1e-13); KEGG: dra:DR2406 ComA protein, ev=6e-58, 67% identity YP_603672.1 PFAM: polysaccharide pyruvyl transferase: (2.3e-65); KEGG: dra:DR0161 hypothetical protein, ev=1e-114, 66% identity YP_603673.1 KEGG: dra:DR0160 hypothetical protein, ev=0.0, 61% identity YP_603674.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_603675.1 PFAM: : (5.6e-13) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (3.7e-10); KEGG: dra:DR0158 leucine dehydrogenase, ev=1e-151, 78% identity YP_603676.1 PFAM: E3 binding: (2.4e-13); KEGG: dra:DR0131 hypothetical protein, ev=4e-66, 37% identity YP_603677.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_603678.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_603679.1 TIGRFAM: SUF system FeS assembly protein: (1.9e-44); PFAM: nitrogen-fixing NifU-like-like: (3.6e-12); KEGG: tth:TTC1374 IscU protein, ev=3e-32, 54% identity YP_603680.1 KEGG: dra:DR0339 N-acyl-L-amino acid amidohydrolase, , ev=1e-180, 78% identity; TIGRFAM: Peptidase M20D, amidohydrolase: (1.5e-151); PFAM: peptidase M20: (3.6e-50) peptidase dimerisation: (4.7e-05) YP_603681.1 KEGG: dra:DR0338 hypothetical protein, ev=1e-09, 31% identity YP_603682.1 PFAM: FAD dependent oxidoreductase: (4.4e-76); KEGG: xcb:XC_1962 oxidoreductase, ev=2e-85, 43% identity YP_603683.1 PFAM: VWA containing CoxE-like: (1e-40); KEGG: reu:Reut_A0421 VWA containing CoxE-like, ev=6e-41, 34% identity YP_603684.1 PFAM: ATPase associated with various cellular activities, AAA_5: (5.6e-12); SMART: ATPase: (1.4e-13); KEGG: sil:SPO2646 hypothetical protein, ev=3e-76, 54% identity YP_603685.1 PFAM: carbon monoxide dehydrogenase subunit G: (3.6e-42); KEGG: dra:DR2247 hypothetical protein, ev=5e-43, 55% identity YP_603686.1 KEGG: dra:DRA0004 hypothetical protein, ev=2e-37, 45% identity YP_603687.1 TIGRFAM: cation diffusion facilitator family transporter: (4.2e-85); PFAM: cation efflux protein: (2.5e-109); KEGG: dra:DR1102 cation efflux system protein, ev=1e-118, 75% identity YP_603688.1 PFAM: CHAD: (6e-09); KEGG: dra:DR2614 hypothetical protein, ev=6e-57, 51% identity YP_603689.1 PFAM: metallophosphoesterase: (4.4e-14); KEGG: dra:DR0295 phosphoprotein phosphatase, ev=7e-97, 64% identity YP_603690.1 KEGG: dra:DR0296 hypothetical protein, ev=1e-27, 71% identity YP_603691.1 TIGRFAM: Twin-arginine translocation pathway signal: (0.082); PFAM: metallophosphoesterase: (1.4e-18); KEGG: dra:DR2345 hypothetical protein, ev=1e-89, 59% identity YP_603692.1 KEGG: dra:DR0039 hypothetical protein, ev=1e-123, 63% identity; TIGRFAM: uncharacterized domain HDIG: (0.0017); PFAM: GAF: (1.5e-06) metal-dependent phosphohydrolase, HD subdomain: (1.4e-23); SMART: Metal-dependent phosphohydrolase, HD region: (3.4e-10) YP_603693.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_603694.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_603695.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_603696.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_603697.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes: (9.2e-143) aromatic amino acid beta-eliminating lyase/threonine aldolase: (6.9e-05); KEGG: dra:DR2186 O-acetylhomoserine (thiol)-lyase, ev=1e-175, 73% identity YP_603698.1 PFAM: TM2: (6.7e-07); KEGG: dra:DR2326 hypothetical protein, ev=3e-41, 42% identity YP_603699.1 PFAM: isochorismatase hydrolase: (1.4e-05); KEGG: tte:TTE1842 amidases related to nicotinamidase, ev=3e-28, 36% identity YP_603700.1 NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways YP_603701.1 PFAM: protein phosphatase 2C-like: (3.5e-07); KEGG: dra:DR2513 hypothetical protein, ev=1e-117, 66% identity YP_603702.1 TIGRFAM: YjgF-like protein: (1e-80); PFAM: Endoribonuclease L-PSP: (1e-64); KEGG: dra:DR2512 protein translation inhibitor, , ev=2e-49, 80% identity YP_603703.1 PFAM: PSP1: (1.9e-37); KEGG: dra:DR2511 hypothetical protein, ev=1e-130, 83% identity YP_603705.1 TIGRFAM: Protein of unknown function DUF196: (1.3e-18); KEGG: mta:Moth_0492 protein of unknown function DUF196, ev=5e-22, 52% identity YP_603706.1 TIGRFAM: CRISPR-associated protein Cas1: (8e-88); PFAM: protein of unknown function DUF48: (1.1e-33); KEGG: mta:Moth_0493 CRISPR-associated protein Cas1, ev=3e-87, 47% identity YP_603707.1 TIGRFAM: CRISPR-associated protein Cas4: (6.2e-33); KEGG: eba:ebA3284 predicted RecB family exonuclease, ev=3e-44, 47% identity YP_603708.1 TIGRFAM: CRISPR-associated protein Csd2: (2.3e-123); PFAM: CRISPR-associated protein TM1801: (2e-30); KEGG: mca:MCA0654 CRISPR-associated TM1801 family protein, ev=9e-87, 55% identity YP_603709.1 TIGRFAM: CRISPR-associated protein, CT1133: (1.8e-23); KEGG: hch:HCH_02815 hypothetical protein, ev=6e-37, 29% identity YP_603710.1 TIGRFAM: CRISPR-associated protein, CT1134: (1.6e-23) CRISPR-associated protein Cas5: (1.2e-10); KEGG: msu:MS0988 hypothetical protein, ev=4e-36, 37% identity YP_603711.1 PFAM: metal-dependent phosphohydrolase, HD subdomain: (0.00011); SMART: DEAD/DEAH box helicase-like: (2.2e-07); KEGG: hypothetical protein, ev=1e-110, 40% identity YP_603712.1 PFAM: peptidase M29, aminopeptidase II: (3.2e-196); KEGG: dra:DR2188 aminopeptidase, ev=0.0, 79% identity YP_603713.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_603714.1 PFAM: ROK: (1.7e-54); KEGG: dra:DR2296 glucokinase, ev=1e-128, 76% identity YP_603715.1 KEGG: dra:DR2297 hypothetical protein, ev=8e-34, 83% identity YP_603716.1 PFAM: thioesterase superfamily: (9.4e-12); KEGG: dra:DR2298 hypothetical protein, ev=4e-40, 58% identity YP_603717.1 KEGG: dra:DR2295 hypothetical protein, ev=1e-30, 52% identity YP_603718.1 PFAM: CutA1 divalent ion tolerance protein: (2.9e-53); KEGG: dra:DR2294 periplasmic divalent cation tolerance protein, ev=1e-40, 78% identity YP_603719.1 KEGG: zmo:ZMO0437 hypothetical protein, ev=6e-11, 40% identity YP_603720.1 KEGG: dra:DR0289 endonuclease III, ev=9e-97, 80% identity; TIGRFAM: endonuclease III: (1.1e-129); PFAM: helix-hairpin-helix motif: (0.0012) HhH-GPD: (5e-22); SMART: Iron-sulfur cluster loop: (6.4e-07) YP_603721.1 PFAM: major facilitator superfamily MFS_1: (2.5e-22); KEGG: dra:DR0290 hypothetical protein, ev=1e-175, 78% identity YP_603722.1 PFAM: protein of unknown function DUF164: (1.6e-13); KEGG: dra:DR0291 hypothetical protein, ev=9e-93, 71% identity YP_603723.1 TIGRFAM: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent: (1.5e-186); PFAM: ribonucleotide reductase large subunit: (1.6e-11) Ribonucleotide reductase large subunit, N terminal: (1e-15); KEGG: dra:DR2374 ribonucleoside-diphosphate reductase-related protein, ev=0.0, 79% identity YP_603724.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_603725.1 PFAM: sodium/hydrogen exchanger: (9.9e-49); KEGG: dra:DR2395 Na+/H+ antiporter, , ev=1e-177, 78% identity YP_603726.1 PFAM: cell wall hydrolase/autolysin: (2.2e-50); KEGG: dra:DR2394 N-acetylmuramoyl-L-alanine amidase, ev=0.0, 56% identity YP_603727.1 KEGG: dra:DR0507 DNA polymerase III alpha subunit, ev=0.0, 85% identity; TIGRFAM: DNA polymerase III, alpha subunit: (0); PFAM: PHP-like: (3e-72) nucleic acid binding, OB-fold, tRNA/helicase-type: (8.5e-09); SMART: Phosphoesterase PHP-like: (5.5e-27) YP_603728.1 KEGG: dra:DR0442 twitching motility protein, ev=1e-156, 76% identity; TIGRFAM: twitching motility protein: (5.4e-221); PFAM: type II secretion system protein E: (7e-28); SMART: ATPase: (2.2e-08) YP_603729.1 KEGG: dra:DR0582 hypothetical protein, ev=4e-68, 70% identity YP_603730.1 KEGG: dra:DR0580 acetyltransferase, , ev=1e-118, 84% identity YP_603731.1 PFAM: isochorismatase hydrolase: (0.0006); KEGG: dra:DR0947 hypothetical protein, ev=3e-29, 60% identity YP_603732.1 PFAM: short-chain dehydrogenase/reductase SDR: (1.1e-05); KEGG: dra:DR1967 enoyl-acyl carrier protein reductase, ev=1e-112, 78% identity YP_603733.1 PFAM: protein of unknown function DUF152: (2e-40); KEGG: dra:DR1966 conserved hypothetical protein, ev=6e-88, 69% identity YP_603734.1 TIGRFAM: HAD-superfamily hydrolase subfamily IIIA: (1.3e-33) HAD-superfamily phosphatase subfamily IIIA: (1e-40); KEGG: dra:DR1965 hypothetical protein, ev=2e-71, 78% identity YP_603735.1 PFAM: type II secretion system protein E: (2.1e-107) General secretory system II, protein E-like: (6e-40); KEGG: dra:DR1964 general secretion pathway protein E, ev=0.0, 78% identity YP_603736.1 KEGG: dra:DR1963 twitching mobility protein, ev=1e-176, 78% identity; TIGRFAM: twitching motility protein: (1.8e-226); PFAM: type II secretion system protein E: (2.4e-23); SMART: ATPase: (3.3e-07) YP_603737.1 KEGG: dra:DR2599 hypothetical protein, ev=1e-141, 57% identity YP_603738.1 PFAM: transposase IS66: (0.00029); KEGG: dra:DRC0028 transposase, , ev=1e-172, 86% identity YP_603739.1 PFAM: protein of unknown function UPF0047: (4.8e-53); KEGG: dra:DR2598 hypothetical protein, ev=5e-62, 80% identity YP_603740.1 PFAM: Nitric oxide synthase, NOS: (6.3e-121); KEGG: dra:DR2597 nitric oxide synthase-related protein, ev=1e-108, 59% identity YP_603741.1 PFAM: peptidase S45, penicillin amidase: (7.3e-191); KEGG: tth:TTC1972 penicillin acylase, ev=1e-173, 45% identity YP_603742.1 PFAM: protein of unknown function DUF6, transmembrane: (1.3e-19); KEGG: bpm:BURPS1710b_1335 transporter ev=8e-37, 36% identity YP_603743.1 TIGRFAM: primosomal protein N': (3.2e-76); KEGG: dra:DR2606 primosomal protein N', , ev=0.0, 65% identity YP_603744.1 PFAM: metallophosphoesterase: (8.2e-07); KEGG: dra:DR2233 hypothetical protein, ev=1e-113, 79% identity YP_603745.1 KEGG: dra:DR2232 hypothetical protein, ev=7e-99, 71% identity YP_603746.1 shows similarity to CbiX(S) YP_603747.1 KEGG: dra:DR2240 hypothetical protein, ev=2e-56, 75% identity YP_603748.1 PFAM: peptidase M20: (5.2e-14) peptidase dimerisation: (7.3e-10); KEGG: dra:DR2239 acetylornithine deacetylase, , ev=1e-151, 76% identity YP_603749.1 PFAM: peptidase S41: (1e-39); SMART: PDZ/DHR/GLGF: (3.1e-07); KEGG: dra:DR1308 protease, , ev=1e-153, 64% identity YP_603751.1 KEGG: dra:DR2265 hypothetical protein, ev=0.0, 69% identity YP_603752.1 PFAM: beta-lactamase-like: (1e-25); KEGG: dra:DR2264 zinc metallohydrolase, glyoxalase II family, ev=1e-112, 70% identity YP_603753.1 PFAM: Ferritin and Dps: (5.1e-29); KEGG: dra:DR2263 DNA-binding stress response protein, Dps family, ev=6e-87, 77% identity YP_603754.1 KEGG: dra:DR2262 hypothetical protein, ev=8e-67, 76% identity YP_603755.1 KEGG: dra:DR0645 molybdopterin-guanine dinucleotide biosynthesis protein A, , ev=3e-48, 58% identity YP_603756.1 KEGG: dra:DR0644 hypothetical protein, ev=3e-16, 29% identity YP_603757.1 PFAM: conserved hypothetical protein 95: (8.4e-56) methyltransferase small: (0.00034); KEGG: dra:DR0643 N-6 adenine-specific DNA restriction methylase, , ev=9e-61, 63% identity YP_603758.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_603759.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_603760.1 PFAM: GCN5-related N-acetyltransferase: (3.8e-21); KEGG: tfu:Tfu_1670 acetyltransferase, ev=2e-16, 35% identity YP_603761.1 KEGG: dra:DR2006 hypothetical protein, ev=2e-47, 62% identity YP_603762.1 KEGG: dra:DR2007 hypothetical protein, ev=1e-27, 80% identity YP_603764.1 TIGRFAM: arginase: (1.4e-115); PFAM: Arginase/agmatinase/formiminoglutamase: (2.9e-105); KEGG: dra:DR0651 arginase, ev=1e-137, 81% identity YP_603765.1 PFAM: metallophosphoesterase: (3.1e-06); KEGG: ttj:TTHA0053 hypothetical protein, ev=1e-39, 47% identity YP_603766.1 KEGG: dra:DR2231 hypothetical protein, ev=7e-49, 72% identity YP_603767.1 KEGG: dra:DR0070 hypothetical protein, ev=1e-71, 72% identity YP_603768.1 PFAM: protein of unknown function DUF450: (1.1e-11); KEGG: dra:DR0137 hypothetical protein, ev=7e-92, 54% identity YP_603769.1 TIGRFAM: Phenylacetic acid degradation-related protein: (1.2e-21) Phenylacetic acid degradation protein PaaD: (1.5e-59); PFAM: thioesterase superfamily: (6.5e-22); KEGG: dra:DR2321 phenylacetic acid degradation protein PaaI, , ev=3e-51, 83% identity YP_603770.1 PFAM: peptidase M42: (1.1e-99); KEGG: dra:DR0946 hypothetical protein, ev=1e-152, 80% identity YP_603771.1 PFAM: Silent information regulator protein Sir2: (1.1e-71); KEGG: dra:DR0016 hypothetical protein, ev=4e-89, 69% identity YP_603772.1 TIGRFAM: riboflavin biosynthesis protein RibD: (3.2e-109); PFAM: CMP/dCMP deaminase, zinc-binding: (4.4e-41) bifunctional deaminase-reductase-like: (7.3e-39); KEGG: dra:DR0153 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase, ev=1e-119, 65% identity YP_603773.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_603774.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase: (1.1e-114) GTP cyclohydrolase II: (2e-108); KEGG: dra:DR0155 GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase, ev=0.0, 84% identity YP_603775.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_603776.1 PFAM: protein of unknown function DUF512: (3.2e-117); SMART: PDZ/DHR/GLGF: (9.4e-10); KEGG: dra:DR2521 hypothetical protein, ev=0.0, 82% identity YP_603777.1 TIGRFAM: large conductance mechanosensitive channel protein: (2.7e-26); PFAM: large-conductance mechanosensitive channel: (2.5e-35); KEGG: dra:DR2422 large conductance mechanosensitive channel, ev=2e-41, 64% identity YP_603778.1 PFAM: von Willebrand factor, type A: (0.0015); KEGG: dra:DR2391 hypothetical protein, ev=0.0, 92% identity YP_603779.1 KEGG: ttj:TTHB179 hypothetical protein, ev=4e-11, 40% identity YP_603780.1 PFAM: transposase, IS4: (0.00017); KEGG: tth:TTC1433 hypothetical protein, ev=5e-31, 33% identity YP_603781.1 TIGRFAM: Protein of unknown function DUF11: (1.2e-09); KEGG: dra:DRB0037 hypothetical protein, ev=3e-57, 31% identity YP_603782.1 PFAM: protein of unknown function DUF11: (3.7e-09); KEGG: dra:DRB0039 hypothetical protein, ev=0.0, 50% identity YP_603783.1 KEGG: dra:DR2392 hypothetical protein, ev=0.0, 61% identity YP_603784.1 PFAM: protein of unknown function DUF11: (0.00024); KEGG: mmu:239611 mucin 19 Pfam: VWD TIL Cys_knot PROSITE: VWFC_1 CTCK_1 ALA_RICH SER_RICH THR_RICH CTCK_2 VWFC_2, ev=3e-27, 24% identity YP_603785.1 PFAM: protein of unknown function DUF6, transmembrane: (1.5e-15); KEGG: dra:DR2393 hypothetical protein, ev=1e-112, 71% identity YP_603786.1 KEGG: dra:DR2018 hypothetical protein, ev=3e-25, 43% identity YP_603787.1 PFAM: regulatory protein, LuxR: (3.4e-19) response regulator receiver: (1.1e-39) Sigma-70, region 4 type 2: (0.00042); KEGG: dra:DR0432 DNA-binding response regulator, ev=1e-108, 94% identity YP_603788.1 PFAM: beta-lactamase: (0.00059); KEGG: dra:DR0433 beta-lactamase, , ev=1e-100, 69% identity YP_603789.1 PFAM: cytochrome c, class I: (4.8e-08); KEGG: dra:DR0434 cytochrome c6, , ev=1e-123, 73% identity YP_603790.1 PFAM: Rieske [2Fe-2S] region: (2.1e-11); KEGG: dra:DR0435 cytochrome complex iron-sulfur subunit, , ev=3e-53, 56% identity YP_603791.1 PFAM: cytochrome b/b6-like: (4e-17); KEGG: dra:DR0436 ubiquinol-cytochrome c reductase cytochrome b subunit, ev=0.0, 81% identity YP_603792.1 KEGG: dra:DR0437 hypothetical protein, ev=7e-07, 55% identity YP_603793.1 PFAM: mannose-6-phosphate isomerase, type I: (1.3e-09); KEGG: dra:DRA0048 mannose-6-phosphate isomerase, , ev=7e-94, 58% identity YP_603795.1 PFAM: HesB/YadR/YfhF: (1.8e-33); KEGG: dra:DR0439 HesB/YadR/YfhF family protein, ev=5e-62, 84% identity YP_603796.1 PFAM: extracellular solute-binding protein, family 5: (3.6e-56); KEGG: ttj:TTHA1634 peptide ABC transporter peptide-binding protein, ev=1e-134, 44% identity YP_603797.1 PFAM: binding-protein-dependent transport systems inner membrane component: (3.6e-43); KEGG: ttj:TTHA1633 peptide ABC transporter permease, ev=1e-104, 58% identity YP_603798.1 PFAM: binding-protein-dependent transport systems inner membrane component: (3.1e-42); KEGG: bld:BLi01228 oligopeptide ABC transporter (permease); RBL00621, ev=6e-72, 45% identity YP_603799.1 PFAM: Crossover junction endodeoxyribonuclease RuvC: (7.4e-37); KEGG: dra:DR0440 Holliday junction resolvase, ev=3e-81, 90% identity YP_603800.1 KEGG: dra:DR0441 hypothetical protein, ev=6e-49, 62% identity YP_603801.1 TIGRFAM: molybdopterin converting factor, subunit 1: (2.1e-31); PFAM: molybdopterin biosynthesis MoaE: (2.5e-39) thiamineS: (2.3e-22); KEGG: dra:DR2607 molybdenum cofactor biosynthesis protein D/E, ev=5e-84, 66% identity YP_603802.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_603803.1 PFAM: S-layer-like region: (5e-20); KEGG: ttj:TTHA1893 S-layer protein precursor (P100 protein), ev=1e-135, 36% identity YP_603804.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_603805.1 TIGRFAM: FolC bifunctional protein: (1.6e-122); PFAM: cytoplasmic peptidoglycan synthetases-like: (3.7e-11) Mur ligase, middle region: (1.7e-08); KEGG: dra:DR2575 folyl-polyglutamate synthetase, ev=1e-126, 69% identity YP_603806.1 PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase: (8.4e-164); KEGG: sru:SRU_2485 carboxypeptidase, ev=1e-126, 47% identity YP_603808.1 PFAM: helix-turn-helix motif: (2.3e-15); KEGG: dra:DR2574 transcriptional regulator, HTH_3 family, ev=8e-64, 92% identity YP_603809.1 KEGG: dra:DR2572 hypothetical protein, ev=1e-86, 43% identity YP_603810.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_603811.1 PFAM: protein of unknown function DUF177: (1.5e-32); KEGG: dra:DR2570 hypothetical protein, ev=5e-85, 69% identity YP_603812.1 TIGRFAM: glucose-1-phosphate thymidyltransferase: (3.9e-210); PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase: (0.0011) Nucleotidyl transferase: (4.1e-65); KEGG: dra:DRA0031 glucose-1-phosphate thymidylyltransferase, , ev=1e-155, 75% identity YP_603813.1 PFAM: Nucleotidyl transferase: (3.2e-70); KEGG: dra:DRA0032 mannose-1-phosphate guanylyltransferase, ev=1e-157, 76% identity YP_603814.1 PFAM: lipopolysaccharide biosynthesis: (0.00015); KEGG: dra:DRA0033 ExoP-related protein, ev=0.0, 67% identity YP_603815.1 PFAM: sugar transferase: (1.2e-86); KEGG: dra:DRA0034 UDP-galactose-lipid carrier transferase, ev=1e-175, 64% identity YP_603816.1 PFAM: polysaccharide biosynthesis protein: (9.1e-22); KEGG: ava:Ava_1044 polysaccharide biosynthesis protein, ev=5e-17, 24% identity YP_603817.1 PFAM: glycosyl transferase, family 2: (1.4e-23); KEGG: gka:GK3313 glycosyltransferase, ev=2e-33, 30% identity YP_603818.1 KEGG: bur:Bcep18194_B1815 hypothetical protein, ev=2e-16, 29% identity YP_603819.1 PFAM: glycosyl transferase, group 1: (8.9e-31); KEGG: dra:DRA0039 mannosyltransferase, ev=8e-76, 46% identity YP_603820.1 KEGG: syf:Synpcc7942_2420 serine O-acetyltransferase, ev=7e-29, 45% identity YP_603821.1 PFAM: glycosyl transferase, group 1: (4.6e-28); KEGG: pst:PSPTO3448 glycosyl transferase, group 1 family protein, ev=1e-105, 53% identity YP_603823.1 PFAM: O-antigen polymerase: (7.6e-13); KEGG: dra:DRA0046 hypothetical protein, ev=1e-146, 67% identity YP_603824.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal: (1.7e-05) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I: (1.2e-44) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II: (2.2e-07) phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III: (1.4e-07); KEGG: dra:DRA0047 phosphomannomutase, ev=0.0, 78% identity YP_603825.1 E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_603826.1 PFAM: response regulator receiver: (4.2e-23); KEGG: ttj:TTHB173 response regulator, ev=3e-37, 48% identity YP_603827.1 PFAM: ATP-binding region, ATPase-like: (3e-24); KEGG: bha:BH3839 two-component sensor histidine kinase, ev=4e-60, 31% identity YP_603828.1 PFAM: sodium:dicarboxylate symporter: (1e-173); KEGG: dra:DR2525 C4-dicarboxylate transport protein, ev=0.0, 77% identity YP_603829.1 PFAM: Indigoidine synthase A like protein: (1.2e-198); KEGG: dra:DR2311 hypothetical protein, ev=1e-136, 81% identity YP_603830.1 PFAM: PfkB: (2.9e-60) Helix-turn-helix, type 11: (0.0012); KEGG: dra:DR2312 carbohydrate kinase, PfkB family, ev=1e-127, 67% identity YP_603831.1 PFAM: HpcH/HpaI aldolase: (6.5e-47); KEGG: dra:DR2206 citrate lyase beta chain, ev=1e-119, 79% identity YP_603832.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (3.7e-14); KEGG: dra:DR2208 lactoylglutathione lyase, , ev=1e-55, 79% identity YP_603833.1 PFAM: protein of unknown function RIO1: (6.1e-16); KEGG: dra:DR2209 SudD-related protein, ev=1e-109, 70% identity YP_603834.1 PFAM: Mg2+ transporter protein, CorA-like: (8.2e-15); KEGG: mta:Moth_0267 magnesium and cobalt transport protein CorA, ev=1e-25, 25% identity YP_603835.1 KEGG: dra:DR0268 sulfonate/nitrate/taurine transport system substrate-binding protein, ev=1e-129, 73% identity YP_603836.1 KEGG: dra:DR0269 hypothetical protein, ev=9e-77, 57% identity YP_603837.1 PFAM: peptidase S9, prolyl oligopeptidase active site region: (6.5e-57) WD40-like beta Propeller: (3.2e-07); KEGG: dra:DR0165 acyl-peptide hydrolase, , ev=0.0, 68% identity YP_603838.1 PFAM: peptidase M20: (4.5e-31) peptidase dimerisation: (1.1e-26); KEGG: dra:DR2493 carboxypeptidase G2, ev=1e-148, 73% identity YP_603839.1 KEGG: dra:DR2491 hypothetical protein, ev=3e-30, 64% identity YP_603840.1 PFAM: LmbE-like protein: (1.2e-46); KEGG: dra:DR0081 hypothetical protein, ev=1e-93, 76% identity YP_603841.1 PFAM: GCN5-related N-acetyltransferase: (7.9e-12); KEGG: sma:SAV6566 acetyltransferase, ev=6e-25, 31% identity YP_603842.1 PFAM: GCN5-related N-acetyltransferase: (1.4e-10); KEGG: dra:DR1057 phosphinothricin acetyltransferase, , ev=1e-71, 49% identity YP_603843.1 KEGG: dra:DR1210 hypothetical protein, ev=5e-81, 65% identity YP_603844.1 PFAM: protein of unknown function DUF165: (2.1e-05); KEGG: dra:DR0380 hypothetical protein, ev=3e-67, 78% identity YP_603845.1 KEGG: dra:DR0381 hypothetical protein, ev=3e-37, 67% identity YP_603846.1 PFAM: peptidase A24A, prepilin type IV: (2.6e-12) peptidase A24A-like: (7.5e-38); KEGG: dra:DR2065 leader peptidase (prepilin peptidase) / N-methyltransferase, ev=1e-156, 71% identity YP_603847.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_603848.1 TIGRFAM: septum site-determining protein MinD: (7.4e-185); PFAM: Cobyrinic acid a,c-diamide synthase: (1e-32); KEGG: dra:DR0752 septum site-determining protein, ev=1e-122, 84% identity YP_603849.1 TIGRFAM: cell division topological specificity factor MinE: (9.7e-27); PFAM: Septum formation topological specificity factor MinE: (4.7e-06); KEGG: dra:DR0751 cell division topological specificity factor, ev=9e-28, 78% identity YP_603850.1 PFAM: short-chain dehydrogenase/reductase SDR: (7.7e-08); KEGG: bld:BLi01190 hypothetical protein, ev=6e-52, 43% identity YP_603851.1 PFAM: aldo/keto reductase: (2.3e-68); KEGG: dra:DR2317 potassium channel, beta subunit, , ev=1e-149, 81% identity YP_603852.1 KEGG: dra:DRB0034 GGDEF family protein, ev=3e-33, 42% identity; TIGRFAM: GGDEF domain: (9.9e-32); PFAM: GGDEF: (3.1e-45) Tetratricopeptide TPR_4: (0.003); SMART: Tetratricopeptide region: (0.18) YP_603853.1 PFAM: ABC transporter related: (2.5e-47); SMART: ATPase: (2.4e-16); KEGG: dra:DR2316 ABC transporter ATP-binding protein, ev=1e-131, 76% identity YP_603854.1 KEGG: dra:DR2315 hypothetical protein, ev=1e-106, 67% identity YP_603855.1 KEGG: dra:DR2314 hypothetical protein, ev=5e-20, 49% identity YP_603856.1 KEGG: dra:DR2229 hypothetical protein, ev=1e-26, 51% identity YP_603857.1 PFAM: protein of unknown function DUF182: (1.2e-22); KEGG: sma:SAV1536 xanthine dehydrogenase accessory factor, ev=1e-47, 38% identity YP_603858.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_603859.1 PFAM: protein of unknown function DUF454: (4.4e-21); KEGG: dra:DR1457 hypothetical protein, ev=3e-47, 73% identity YP_603860.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (5.4e-05); KEGG: dra:DR1869 polyferredoxin, , ev=1e-139, 68% identity YP_603861.1 PFAM: ATP-binding region, ATPase-like: (3.7e-34) histidine kinase A-like: (0.00028); KEGG: dra:DRB0029 sensor histidine kinase/response regulator, ev=7e-46, 44% identity YP_603862.1 PFAM: helicase-like: (2.8e-13) DEAD/DEAH box helicase-like: (2.3e-24); KEGG: dra:DR0065 ATP-dependent helicase, , ev=0.0, 79% identity YP_603863.1 KEGG: dra:DR0383 S-layer-like array-related protein, ev=4e-50, 55% identity YP_603864.1 KEGG: dra:DR0043 hypothetical protein, ev=5e-81, 62% identity YP_603865.1 PFAM: Mandelate racemase/muconate lactonizing enzyme-like: (1.9e-09); KEGG: dra:DR0044 N-acylamino acid racemase, ev=1e-177, 82% identity YP_603866.1 PFAM: acyl-coA-binding protein, ACBP: (2.5e-37); KEGG: dra:DR0166 acyl-CoA-binding protein, ev=4e-28, 75% identity YP_603867.1 PFAM: protein of unknown function DUF955: (1.6e-19); KEGG: dra:DR0167 hypothetical protein, ev=5e-92, 66% identity YP_603868.1 KEGG: dra:DR0168 dihydropteroate synthase, ev=1e-113, 70% identity; TIGRFAM: dihydropteroate synthase: (1.8e-124); PFAM: dihydropteroate synthase, DHPS: (2.2e-98) YP_603869.1 TIGRFAM: dihydroneopterin aldolase: (1.7e-49); KEGG: dra:DR0169 dihydroneopterin aldolase, ev=6e-44, 76% identity YP_603870.1 KEGG: dra:DR0170 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase, ev=3e-54, 69% identity; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase: (1.8e-50); PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK: (1e-47) YP_603871.1 KEGG: dra:DR1212 hypothetical protein, ev=3e-18, 35% identity YP_603872.1 KEGG: dra:DR0040 hypothetical protein, ev=2e-37, 79% identity YP_603873.1 KEGG: dra:DR2063 polynucleotide phosphorylase, ev=0.0, 81% identity; PFAM: 3' exoribonuclease: (4.5e-43) RNA binding S1: (7.5e-19) KH, type 1: (1.3e-09); SMART: KH: (8.3e-09) YP_603874.1 PFAM: molybdopterin oxidoreductase: (2.8e-43) molydopterin dinucleotide-binding region: (2.1e-26) molybdopterin oxidoreductase Fe4S4 region: (0.00016); KEGG: dra:DR0397 molybdopterin oxidoreductase, molybdopterin binding subunit, ev=0.0, 75% identity YP_603875.1 PFAM: arsenate reductase and related: (5.8e-21); KEGG: dra:DR0136 hypothetical protein, ev=9e-43, 70% identity YP_603876.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_603877.1 PFAM: electron transport protein SCO1/SenC: (4.6e-09); KEGG: dra:DR0597 hypothetical protein, ev=5e-68, 58% identity YP_603878.1 PFAM: cytochrome c oxidase, subunit III: (7.3e-11) cytochrome c oxidase, subunit I: (6e-176); KEGG: dra:DR2620 cytochrome c oxidase, subunit I / III, ev=0.0, 82% identity YP_603879.1 PFAM: cytochrome c oxidase, subunit II: (6.3e-09) cytochrome C oxidase subunit II, transmembrane region: (0.0021); KEGG: dra:DR2619 cytochrome c oxidase, subunit II, ev=5e-83, 52% identity YP_603880.1 converts protoheme IX and farnesyl diphosphate to heme O YP_603881.1 PFAM: cytochrome oxidase assembly: (2e-06); KEGG: dra:DR2617 cytochrome AA3-controlling protein CtaA, , ev=1e-133, 75% identity YP_603882.1 PFAM: protein of unknown function DUF420: (1.8e-77); KEGG: dra:DR2616 hypothetical protein, ev=9e-70, 78% identity YP_603883.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_603884.1 KEGG: dra:DR2594 magnesium protoporphyrin chelatase, , ev=0.0, 87% identity YP_603885.1 KEGG: dra:DR2593 hypothetical protein, ev=1e-30, 63% identity YP_603886.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_603887.1 KEGG: dra:DR2554 hypothetical protein, ev=3e-44, 48% identity YP_603888.1 PFAM: PfkB: (2.4e-41); KEGG: dra:DR2553 carbohydrate kinase, , ev=1e-141, 81% identity YP_603889.1 PFAM: aminodeoxychorismate lyase: (2.9e-109); KEGG: dra:DR2552 hypothetical protein, ev=1e-127, 69% identity YP_603890.1 KEGG: dra:DR0047 hypothetical protein, ev=4e-13, 61% identity YP_603891.1 PFAM: alpha/beta hydrolase fold: (1.1e-12); KEGG: dra:DR2549 epoxide hydrolase-related protein, ev=1e-92, 68% identity YP_603892.1 KEGG: dra:DRA0270 adenine deaminase, ev=0.0, 76% identity; TIGRFAM: adenine deaminase: (8.3e-135); PFAM: amidohydrolase: (2.9e-29) YP_603893.1 KEGG: dra:DR2504 hypothetical protein, ev=1e-100, 70% identity YP_603894.1 KEGG: dra:DR2505 hypothetical protein, ev=1e-133, 67% identity YP_603895.1 PFAM: esterase: (1.2e-65); KEGG: dra:DR2506 ferric enterobactin esterase-related protein, ev=1e-160, 77% identity YP_603896.1 PFAM: AMP-dependent synthetase and ligase: (7.3e-103); KEGG: dra:DR2507 medium-chain fatty acid--CoA ligase, ev=0.0, 78% identity YP_603897.1 PFAM: Holliday junction resolvase YqgF: (1.2e-35); SMART: Resolvase, RNase H-like fold: (4.6e-21); KEGG: dra:DR2509 Holliday junction resolvase, ev=2e-50, 83% identity YP_603898.1 PFAM: protein of unknown function DUF179: (9.1e-54); KEGG: dra:DR0357 transcriptional regulator, ev=6e-64, 66% identity YP_603899.1 KEGG: dra:DR0349 ATP-dependent protease LA, ev=0.0, 85% identity; TIGRFAM: ATP-dependent protease La: (0); PFAM: peptidase S16, lon-like: (2.8e-12) AAA ATPase, central region: (1.4e-49) ATPase associated with various cellular activities, AAA_3: (6.6e-05) ATPase associated with various cellular activities, AAA_5: (2.7e-08); SMART: ATPase: (1.8e-15) YP_603900.1 PFAM: acyl-CoA dehydrogenase-like: (2.9e-63) Acyl-CoA dehydrogenase, type 2-like: (8.1e-27); KEGG: dra:DR0922 acyl-CoA dehydrogenase, ev=0.0, 88% identity YP_603902.1 PFAM: IS1 transposase: (7.4e-22); KEGG: sru:SRU_2704 ISSru3, transposase InsB, ev=1e-21, 41% identity YP_603903.1 PFAM: phage integrase: (7.6e-29); KEGG: mta:Moth_1501 tyrosine recombinase XerD, ev=2e-25, 30% identity YP_603904.1 PFAM: trigger factor-like: (8.4e-41); KEGG: dra:DR1948 trigger factor, ev=1e-175, 67% identity YP_603905.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_603906.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase: (1.8e-118); PFAM: acyl transferase region: (1.8e-14); KEGG: dra:DR1945 malonyl CoA-acyl carrier protein transacylase, ev=1e-126, 76% identity YP_603907.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase: (2.3e-160); PFAM: NAD-dependent epimerase/dehydratase: (0.0019) short-chain dehydrogenase/reductase SDR: (4.3e-46); KEGG: dra:DR1943 3-oxoacyl-[acyl-carrier protein] reductase, ev=1e-103, 78% identity YP_603908.1 carries the fatty acid chain in fatty acid biosynthesis YP_603909.1 PFAM: beta-ketoacyl synthase: (4.1e-80); KEGG: dra:DR1941 3-oxoacyl-[acyl-carrier-protein] synthase II, ev=0.0, 79% identity YP_603910.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_603911.1 PFAM: Tetratricopeptide TPR_4: (0.1); KEGG: dra:DR0724 hypothetical protein, ev=6e-15, 26% identity YP_603912.1 KEGG: dra:DR2001 hypothetical protein, ev=1e-27, 63% identity YP_603913.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_603914.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_603915.1 KEGG: dra:DR0495 pyridoxamine 5-phosphate oxidase, ev=8e-98, 78% identity; TIGRFAM: pyridoxamine 5'-phosphate oxidase: (3.8e-96); PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding: (4.7e-32) YP_603916.1 KEGG: syf:Synpcc7942_2500 hypothetical protein, ev=9e-07, 27% identity YP_603917.1 PFAM: band 7 protein: (1.5e-28); KEGG: syf:Synpcc7942_2499 band 7 protein, ev=5e-70, 41% identity YP_603918.1 PFAM: OsmC-like protein: (5.6e-35); KEGG: dra:DR1857 organic hydroperoxide resistance protein, ev=1e-57, 78% identity YP_603919.1 KEGG: dra:DR1664 hypothetical protein, ev=8e-66, 72% identity YP_603920.1 KEGG: dra:DR1663 hypothetical protein, ev=1e-43, 58% identity YP_603921.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_603922.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_603923.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_603924.1 KEGG: dra:DR1456 ribose-phosphate pyrophosphokinase, ev=1e-156, 88% identity; TIGRFAM: ribose-phosphate pyrophosphokinase: (1.3e-120); PFAM: phosphoribosyltransferase: (2e-23) YP_603925.1 KEGG: ana:all1724 unknown protein, ev=2e-12, 27% identity YP_603926.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (1.2e-06); KEGG: dra:DR1764 hypothetical protein, ev=3e-99, 65% identity YP_603927.1 PFAM: Rieske [2Fe-2S] region: (2.4e-22); KEGG: dra:DR1950 ferredoxin, , ev=3e-36, 72% identity YP_603929.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin: (1.4e-31); KEGG: dra:DR1937 serine protease, subtilase family, ev=1e-140, 65% identity YP_603930.1 PFAM: NAD-dependent epimerase/dehydratase: (0.00057) short-chain dehydrogenase/reductase SDR: (2.4e-29); KEGG: dra:DR1938 oxidoreductase, short-chain dehydrogenase/reductase family, ev=4e-95, 73% identity YP_603931.1 KEGG: dra:DR1192 hypothetical protein, ev=1e-168, 81% identity YP_603932.1 KEGG: dra:DR0353 ribonuclease R, ev=0.0, 75% identity; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases: (9.2e-161) Ribonuclease R: (2.1e-237); PFAM: ribonuclease II: (2.6e-87) RNA binding S1: (1.5e-13) Ribonuclease B, OB region-like: (4.7e-18); SMART: Cold shock protein: (4.5e-06) YP_603933.1 KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47) YP_603934.1 KEGG: dra:DR0355 hypothetical protein, ev=9e-41, 73% identity YP_603935.1 PFAM: Methionine biosynthesis MetW: (0.00046) Methyltransferase type 11: (9.5e-28) Methyltransferase type 12: (2.2e-15); KEGG: dra:DR0356 methyltransferase, , BioC family, ev=8e-39, 55% identity YP_603936.1 PFAM: transposase, IS4: (0.00017); KEGG: tth:TTC1433 hypothetical protein, ev=5e-31, 33% identity YP_603937.1 KEGG: dra:DR2563 hypothetical protein, ev=8e-07, 43% identity YP_603938.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase: (2.8e-259); PFAM: ATP-dependent carboxylate-amine ligase-like, ATP-grasp: (0.001) Carbamoyl-phosphate synthase L chain, ATP-binding: (7.1e-89) Carbamoyl-phosphate synthetase large chain-like: (1.3e-45) biotin carboxylase-like: (1.9e-65); KEGG: dra:DR0117 biotin carboxylase, ev=0.0, 89% identity YP_603939.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein: (2e-45); PFAM: biotin/lipoyl attachment: (1.7e-31); KEGG: dra:DR0118 acetyl-CoA carboxylase biotin carboxyl carrier protein, ev=3e-57, 67% identity YP_603940.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_603941.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_603942.1 PFAM: protein of unknown function DUF1211: (1e-40); KEGG: cvi:CV0104 hypothetical protein, ev=3e-58, 55% identity YP_603943.1 TIGRFAM: FeS assembly protein SufD: (2e-86); PFAM: SufBD: (2.9e-44); KEGG: dra:DR2101 hypothetical protein, ev=0.0, 89% identity YP_603944.1 TIGRFAM: FeS assembly protein SufB: (0); PFAM: SufBD: (5.8e-119); KEGG: dra:DR2106 hypothetical protein, ev=0.0, 94% identity YP_603945.1 TIGRFAM: FeS assembly ATPase SufC: (1e-154); PFAM: ABC transporter related: (2.6e-33); KEGG: dra:DR2107 ABC transporter ATP-binding protein, Ycf16 family, ev=1e-130, 93% identity YP_603946.1 PFAM: alpha amylase, catalytic region: (5.5e-72); SMART: Alpha amylase, catalytic subdomain: (2e-92); KEGG: dra:DR0723 glycosyl hydrolase, family 13, ev=0.0, 63% identity YP_603947.1 TIGRFAM: RNA polymerase sigma factor RpoD-like: (1.5e-177); PFAM: sigma-70 region 3: (1e-24) sigma-70 region 2: (1.8e-24) sigma-70 region 4: (2.7e-22) sigma-70 region 1.2: (7.7e-20); KEGG: dra:DR0916 RNA polymerase sigma-A factor, ev=1e-179, 90% identity YP_603949.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_603951.1 KEGG: dra:DR0214 hypothetical protein, ev=6e-76, 64% identity YP_603952.1 PFAM: GCN5-related N-acetyltransferase: (7.1e-14); KEGG: dra:DR0213 hypothetical protein, ev=4e-96, 64% identity YP_603953.1 KEGG: dra:DR0212 hypothetical protein, ev=2e-36, 68% identity YP_603954.1 PFAM: protein of unknown function DUF218: (6.1e-32); KEGG: dra:DR0210 hypothetical protein, ev=3e-88, 70% identity YP_603955.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_603956.1 TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase: (9.6e-158); PFAM: cytoplasmic peptidoglycan synthetases-like: (1.2e-06) Mur ligase, middle region: (5.1e-35); KEGG: dra:DR2496 UDP-N-acetylmuramoylalanine--D-glutamiate ligase, ev=1e-171, 74% identity YP_603957.1 PFAM: cell cycle protein: (9.8e-43); KEGG: dra:DR2497 cell division protein, FtsW/RodA/SpoVE family, ev=1e-147, 71% identity YP_603958.1 KEGG: dra:DR1575 hypothetical protein, ev=1e-53, 55% identity YP_603959.1 PFAM: Allergen V5/Tpx-1 related: (9.5e-26) Ig-like, group 2: (0.0011); KEGG: dra:DR1548 hypothetical protein, ev=6e-48, 65% identity YP_603960.1 PFAM: carboxyl transferase: (4.4e-268); KEGG: dra:DR1316 propionyl-CoA carboxylase beta chain, ev=0.0, 85% identity YP_603961.1 KEGG: tfu:Tfu_1264 hypothetical protein, ev=4e-29, 46% identity YP_603962.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_603963.1 KEGG: dra:DR1392 hypothetical protein, ev=1e-132, 83% identity YP_603964.1 PFAM: acyltransferase 3: (1.7e-23); KEGG: mpa:MAP4008 hypothetical protein, ev=9e-41, 34% identity YP_603965.1 PFAM: : (4.3e-121) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (2.9e-74); KEGG: bte:BTH_I1224 glutamate dehydrogenase, ev=0.0, 69% identity YP_603966.1 PFAM: : (2.3e-50) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (2e-55); KEGG: tth:TTC1212 glutamate dehydrogenase, ev=1e-100, 48% identity YP_603967.1 PFAM: Polyprenyl synthetase: (3.3e-53); KEGG: dra:DR0932 polyprenyl synthase, ev=1e-116, 69% identity YP_603968.1 KEGG: dra:DR0195 hypothetical protein, ev=4e-69, 60% identity YP_603969.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase: (5.1e-44); PFAM: glutamine amidotransferase class-I: (1.1e-52) Anthranilate synthase component I and chorismate binding protein: (2.7e-120) Anthranilate synthase component I-like: (1.5e-05); KEGG: dra:DR0196 anthranilate synthase, ev=0.0, 77% identity YP_603970.1 PFAM: protein of unknown function UPF0074: (4.7e-51); KEGG: dra:DR2094 rrf2 protein, ev=1e-68, 86% identity YP_603971.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_603972.1 KEGG: dra:DR1331 hypothetical protein, ev=1e-10, 50% identity YP_603973.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_603974.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_603975.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_603976.1 PFAM: heat shock protein Hsp20: (3.7e-28); KEGG: dra:DR1114 heat shock protein, HSP20 family, ev=5e-66, 79% identity YP_603977.1 PFAM: ABC transporter related: (4.7e-37); SMART: ATPase: (2.7e-21); KEGG: dra:DR1103 ABC transporter ATP-binding protein, EF-3 family, ev=0.0, 77% identity YP_603978.1 KEGG: dra:DR1748 hypothetical protein, ev=2e-67, 84% identity YP_603979.1 PFAM: protein of unknown function DUF490: (0.00011); KEGG: dra:DR1461 hypothetical protein, ev=0.0, 48% identity YP_603980.1 catalyzes the hydrolysis of acylphosphate YP_603981.1 KEGG: pca:Pcar_0661 hypothetical protein, ev=2e-77, 53% identity YP_603982.1 KEGG: dra:DR0869 hypothetical protein, ev=2e-31, 41% identity YP_603983.1 PFAM: Endoribonuclease L-PSP: (8.1e-33); KEGG: sma:SAV75 endoribonuclease L-PSP, ev=3e-31, 55% identity YP_603984.1 involved in de novo purine biosynthesis YP_603985.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase: (8.4e-21); KEGG: dra:DR0867 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase, ev=1e-116, 77% identity YP_603986.1 PFAM: glycosyl transferase, family 2: (3.3e-09); KEGG: lxx:Lxx21080 N-acetyl-glucosamine transferase, ev=2e-41, 35% identity YP_603987.1 PFAM: major intrinsic protein: (3.7e-22); KEGG: gvi:glr0003 probable channel protein, ev=9e-33, 39% identity YP_603988.1 KEGG: dra:DR0872 homoserine O-acetyltransferase, , ev=1e-126, 72% identity; TIGRFAM: homoserine O-acetyltransferase: (2.2e-97); PFAM: alpha/beta hydrolase fold: (7.8e-17) YP_603989.1 KEGG: dra:DR0873 O-acetylhomoserine (thiol)-lyase, ev=0.0, 86% identity; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase: (0); PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes: (9e-206) aromatic amino acid beta-eliminating lyase/threonine aldolase: (0.003) YP_603990.1 PFAM: ferric-uptake regulator: (1.6e-17); KEGG: dra:DR0865 ferric uptake regulation protein, , ev=6e-53, 78% identity YP_603991.1 KEGG: dra:DR0864 hypothetical protein, ev=2e-48, 42% identity YP_603992.1 KEGG: dra:DR0863 hypothetical protein, ev=1e-52, 46% identity YP_603993.1 PFAM: Methyltransferase type 11: (1.1e-21) Methyltransferase type 12: (9.1e-10); KEGG: dra:DR2562 3-demethylubiquinone-9 3-methyltransferase, , ev=4e-66, 64% identity YP_603994.1 PFAM: Squalene/phytoene synthase: (1.6e-91); KEGG: dra:DR0862 phytoene synthase, ev=1e-103, 65% identity YP_603995.1 PFAM: amine oxidase: (5.1e-13); KEGG: dra:DR0861 phytoene dehydrogenase, ev=0.0, 79% identity YP_603996.1 PFAM: alpha/beta hydrolase fold: (8.2e-15); KEGG: dra:DR1537 lipase, , ev=1e-98, 68% identity YP_603997.1 PFAM: OsmC-like protein: (5.6e-29); KEGG: dra:DR1538 osmotically inducible protein C, ev=3e-56, 72% identity YP_603998.1 PFAM: helix-turn-helix, HxlR type: (3.1e-12); KEGG: dra:DR1969 hypothetical protein, ev=2e-43, 83% identity YP_603999.1 PFAM: nitroreductase: (6.9e-52); KEGG: dra:DR1968 nitroreductase, ev=1e-80, 70% identity YP_604000.1 PFAM: Alcohol dehydrogenase, zinc-binding: (2.4e-37) Alcohol dehydrogenase GroES-like: (4.4e-24); KEGG: bcz:BCZK1920 quinone oxidoreductase, ev=7e-69, 43% identity YP_604001.1 PFAM: major facilitator superfamily MFS_1: (5.4e-52); KEGG: dra:DR0472 tetracycline-efflux transporter ev=1e-158, 74% identity YP_604002.1 KEGG: bja:blr6753 hypothetical protein, ev=6e-43, 67% identity YP_604003.1 PFAM: ABC-3: (1.3e-87); KEGG: dra:DR2283 manganese transport system permease, ev=1e-119, 84% identity YP_604004.1 PFAM: ABC transporter related: (2.4e-52); SMART: ATPase: (2.4e-16); KEGG: dra:DR2284 manganese transport system ATP-binding protein, ev=9e-96, 72% identity YP_604005.1 PFAM: periplasmic solute binding protein: (1.9e-77); KEGG: dra:DR2523 adhesin B, ev=3e-98, 68% identity YP_604006.1 required for 70S ribosome assembly YP_604007.1 PFAM: cobalamin synthesis protein, P47K: (7.2e-66) cobalamin synthesis CobW-like: (2e-15); KEGG: bha:BH1790 hypothetical protein, ev=6e-69, 40% identity YP_604008.1 KEGG: dra:DR2036 trehalose synthase, , ev=0.0, 84% identity; TIGRFAM: Trehalose synthase-like: (0); PFAM: alpha amylase, catalytic region: (1.5e-59); SMART: Alpha amylase, catalytic subdomain: (4e-106) YP_604009.1 PFAM: protein of unknown function UPF0005: (6.1e-19); KEGG: dra:DR0893 conserved hypothetical protein, ev=6e-88, 77% identity YP_604010.1 KEGG: dra:DR0463 maltooligosyltrehalose synthase, ev=0.0, 69% identity; TIGRFAM: Malto-oligosyltrehalose synthase: (0); PFAM: alpha amylase, catalytic region: (3.4e-05); SMART: Alpha amylase, catalytic subdomain: (2.8e-09) YP_604011.1 KEGG: dra:DR0464 maltooligosyltrehalose trehalohydrolase, , ev=0.0, 68% identity; TIGRFAM: Malto-oligosyltrehalose trehalohydrolase: (2.9e-289); PFAM: glycoside hydrolase, family 13-like: (1.8e-12) alpha amylase, catalytic region: (4e-09); SMART: Alpha amylase, catalytic subdomain: (9.6e-12) YP_604012.1 KEGG: dra:DR0264 glycogen operon protein GlgX, ev=0.0, 84% identity; TIGRFAM: Glycogen debranching enzyme GlgX: (0); PFAM: glycoside hydrolase, family 13-like: (1.1e-35) alpha amylase, catalytic region: (1.9e-15); SMART: Alpha amylase, catalytic subdomain: (1.2e-11) YP_604013.1 KEGG: dra:DR1693 hypothetical protein, ev=4e-58, 69% identity YP_604014.1 TIGRFAM: ABC transporter substrate-binding protein, aliphatic sulphonates: (2.7e-66); PFAM: NLPA lipoprotein: (3.7e-21); KEGG: dra:DR1655 sulfonate transport system substrate-binding protein, ev=1e-150, 84% identity YP_604015.1 KEGG: dra:DR1818 hypothetical protein, ev=2e-19, 44% identity YP_604016.1 PFAM: helicase-like: (8.9e-18) transcription factor CarD: (8.1e-41) type III restriction enzyme, res subunit: (2.2e-07) DEAD/DEAH box helicase-like: (1.3e-32); KEGG: dra:DR1532 transcription-repair coupling factor, ev=0.0, 83% identity YP_604017.1 KEGG: dra:DR0906 DNA gyrase, subunit B, ev=0.0, 83% identity; PFAM: DNA gyrase, subunit B-like: (1.1e-40) ATP-binding region, ATPase-like: (6.1e-22) TOPRIM: (0.0011) DNA topoisomerase, type IIA, subunit B, region 2: (1e-59); SMART: DNA topoisomerase, type IIA, subunit B or-like: (6.6e-289) YP_604018.1 PFAM: von Willebrand factor, type A: (0.00065); KEGG: dra:DR0904 hypothetical protein, ev=1e-72, 56% identity YP_604019.1 KEGG: dra:DR1878 inosine-5'-monophosphate dehydrogenase, ev=0.0, 85% identity; TIGRFAM: inosine-5'-monophosphate dehydrogenase: (1.3e-272); PFAM: CBS: (2.1e-34) IMP dehydrogenase/GMP reductase: (4.5e-237) YP_604020.1 TIGRFAM: channel protein, hemolysin III family: (1.3e-82); PFAM: Hly-III related proteins: (3.5e-71); KEGG: dra:DR1880 hemolysin, , ev=3e-75, 65% identity YP_604021.1 PFAM: peptidase M50: (1.7e-42); KEGG: dra:DR0982 hypothetical protein, ev=7e-79, 73% identity YP_604022.1 PFAM: Polynucleotide adenylyltransferase region: (1e-21); KEGG: dra:DR0983 tRNA nucleotidyltransferase, , ev=1e-127, 67% identity YP_604023.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap: (1.6e-13); SMART: PDZ/DHR/GLGF: (3.9e-12); KEGG: dra:DR1756 periplasmic serine protease Do, , ev=4e-83, 47% identity YP_604024.1 PFAM: Hsp33 protein: (1.8e-120); KEGG: dra:DR0985 heat shock protein, ev=1e-129, 75% identity YP_604025.1 PFAM: extracellular solute-binding protein, family 5: (2.6e-64); KEGG: dra:DR0986 extracellular solute binding protein, family 5, ev=0.0, 68% identity YP_604026.1 PFAM: regulatory protein, LuxR: (5.8e-26) response regulator receiver: (7.5e-41) Bacterio-opsin activator, HTH: (0.0005); KEGG: dra:DR0987 DNA-binding response regulator, ev=1e-105, 90% identity YP_604027.1 PFAM: GAF: (4.2e-07) ATP-binding region, ATPase-like: (1.5e-19) histidine kinase, dimerisation and phosphoacceptor region: (3.9e-13); SMART: PAS: (2.5e-08); KEGG: dra:DR1227 two-component sensor histidine kinase, ev=0.0, 74% identity YP_604029.1 KEGG: dra:DR1226 hypothetical protein, ev=1e-90, 57% identity YP_604030.1 PFAM: glycosyl transferase, group 1: (1.8e-29); KEGG: dra:DR1225 mannosyltransferase, , ev=1e-156, 69% identity YP_604031.1 PFAM: glycosyl transferase, family 2: (5.4e-30); KEGG: tth:TTC0526 glycosyltransferase, ev=6e-66, 63% identity YP_604032.1 PFAM: major facilitator superfamily MFS_1: (8.3e-35); KEGG: dra:DR1223 multidrug resistance protein-related protein, ev=1e-125, 59% identity YP_604033.1 PFAM: polysaccharide deacetylase: (2.6e-28); KEGG: dra:DR1222 polysaccharide deacetylase, , ev=5e-86, 70% identity YP_604034.1 KEGG: dra:DR2625 hypothetical protein, ev=1e-102, 55% identity YP_604036.1 PFAM: alpha/beta hydrolase fold: (0.00053); KEGG: dra:DRA0060 hypothetical protein, ev=1e-119, 69% identity YP_604037.1 TIGRFAM: GGDEF domain: (7.2e-35); PFAM: GGDEF: (7.3e-46) 5TM Receptors of the LytS-YhcK type, transmembrane region: (1.1e-13); KEGG: dra:DR1090 GGDEF family protein, ev=8e-49, 36% identity YP_604038.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_604039.1 PFAM: protein of unknown function DUF6, transmembrane: (2e-11); KEGG: btk:BT9727_0395 permease, drug/metabolite transporter superfamily, ev=1e-22, 38% identity YP_604040.1 PFAM: protein of unknown function DUF1345: (8.3e-63); KEGG: dra:DR0351 hypothetical protein, ev=4e-57, 59% identity YP_604041.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_604042.1 KEGG: dra:DR1261 hypothetical protein, ev=1e-25, 63% identity YP_604043.1 PFAM: alpha amylase, catalytic region: (2.5e-20); SMART: Alpha amylase, catalytic subdomain: (2.7e-36); KEGG: dra:DR0933 alpha-amlyase, ev=0.0, 74% identity YP_604044.1 PFAM: ribosomal protein L35: (2.6e-09); KEGG: dra:DR2005 50S ribosomal protein L35, ev=1e-24, 82% identity YP_604045.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_604046.1 PFAM: ROK: (5.5e-08); KEGG: dra:DR0823 ROK family protein, ev=1e-104, 77% identity YP_604047.1 PFAM: amidohydrolase: (3.3e-06); KEGG: dra:DR0824 hydrolase, , ev=1e-174, 77% identity YP_604048.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_604049.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_604050.1 TIGRFAM: GGDEF domain: (9.2e-32); PFAM: GGDEF: (6.1e-50); KEGG: ttj:TTHA1641 GGDEF domain protein, ev=3e-42, 38% identity YP_604051.1 PFAM: regulatory protein, LacI: (1.1e-10) periplasmic binding protein/LacI transcriptional regulator: (9.9e-06); KEGG: dra:DR1884 transcriptional regulator, ev=1e-149, 80% identity YP_604052.1 PFAM: protein of unknown function DUF461: (5.9e-30); KEGG: dra:DR1885 hypothetical protein, ev=2e-31, 48% identity YP_604053.1 PFAM: electron transport protein SCO1/SenC: (5.1e-19); KEGG: dra:DR1886 hypothetical protein, ev=3e-57, 64% identity YP_604054.1 KEGG: dra:DR1887 Predicted membrane protein, ev=1e-101, 77% identity YP_604055.1 PFAM: histidinol dehydrogenase: (4.8e-148); KEGG: dra:DR2140 histidinol dehydrogenase, ev=0.0, 84% identity YP_604056.1 KEGG: dra:DR2136 hypothetical protein, ev=5e-76, 71% identity YP_604057.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_604058.1 PFAM: ABC transporter related: (5.4e-65); SMART: ATPase: (3.4e-13); KEGG: dra:DR2134 ABC transporter ATP-binding protein, ev=1e-125, 88% identity YP_604059.1 KEGG: dra:DR2133 hypothetical protein, ev=2e-74, 52% identity YP_604060.1 PFAM: binding-protein-dependent transport systems inner membrane component: (1.1e-22); KEGG: dra:DR1436 multiple sugar transport system permease protein, ev=1e-129, 82% identity YP_604061.1 PFAM: binding-protein-dependent transport systems inner membrane component: (2.2e-09); KEGG: dra:DR1437 multiple sugar transport system permease protein, ev=1e-153, 84% identity YP_604062.1 PFAM: extracellular solute-binding protein, family 1: (3.2e-45); KEGG: dra:DR1438 multiple sugar transport system substrate-binding protein, ev=0.0, 82% identity YP_604063.1 KEGG: dra:DR2199 ATP-dependent DNA helicase RecG-related protein, ev=0.0, 74% identity YP_604064.1 KEGG: dra:DR1989 hypothetical protein, ev=4e-33, 51% identity YP_604065.1 PFAM: tRNA pseudouridine synthase D, TruD: (6.2e-137); KEGG: dra:DR1991 tRNA pseudouridine synthase D, ev=1e-144, 75% identity YP_604066.1 KEGG: dra:DR1293 hypothetical protein, ev=2e-61, 51% identity YP_604067.1 PFAM: molybdopterin binding domain: (4.3e-44); KEGG: dra:DR1292 molybdenum cofactor biosynthesis protein B, ev=2e-58, 62% identity YP_604068.1 KEGG: dra:DR1873 hypothetical protein, ev=5e-38, 38% identity YP_604069.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_604070.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_604071.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_604072.1 TIGRFAM: acetolactate synthase, small subunit: (3.6e-57); PFAM: amino acid-binding ACT: (8e-17); KEGG: dra:DR1517 acetolactate synthase, small subunit, ev=3e-67, 79% identity YP_604073.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type: (1.9e-252); PFAM: thiamine pyrophosphate enzyme-like TPP-binding: (1e-68) thiamine pyrophosphate enzyme, central region: (2e-55) thiamine pyrophosphate enzyme-like TPP binding region: (3.7e-96); KEGG: dra:DR1516 acetolactate synthase large subunit, ev=0.0, 81% identity YP_604074.1 PFAM: helicase-like: (2.5e-35) DEAD/DEAH box helicase-like: (1.1e-65); KEGG: dra:DR1624 RNA helicase, ev=0.0, 80% identity YP_604075.1 TIGRFAM: Pseudouridine synthase, RluD: (3.6e-86); PFAM: RNA-binding S4: (6.5e-10) pseudouridine synthase: (7.6e-57); KEGG: dra:DR1789 ribosomal large subunit pseudouridine synthase D, ev=1e-138, 75% identity YP_604076.1 TIGRFAM: twin-arginine translocation protein, TatA/E family: (1.3e-21); PFAM: sec-independent translocation protein mttA/Hcf106: (3.4e-20); KEGG: dra:DR0292 sec-independent protein translocase, ev=7e-17, 58% identity YP_604077.1 PFAM: sigma-70 region 2: (1.8e-16) sigma-70 region 4: (4.3e-14) Sigma-70, region 4 type 2: (4.6e-13); KEGG: ttj:TTHB211 RNA polymerase sigma factor, ev=2e-27, 40% identity YP_604078.1 KEGG: ttj:TTHB212 hypothetical protein, ev=3e-18, 36% identity YP_604079.1 PFAM: NUDIX hydrolase: (5e-23); KEGG: dra:DR0975 MutT/NUDIX family protein, ev=1e-78, 87% identity YP_604080.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_604081.1 PFAM: homoserine dehydrogenase: (1.5e-46) homoserine dehydrogenase, NAD-binding: (2.2e-15); KEGG: dra:DR1278 homoserine dehydrogenase, ev=1e-138, 76% identity YP_604082.1 PFAM: alpha amylase, catalytic region: (3.5e-93); SMART: Alpha amylase, catalytic subdomain: (1.1e-106); KEGG: dra:DR1141 glycosyl hydrolase, family 13, ev=0.0, 72% identity YP_604083.1 TIGRFAM: uncharacterized domain HDIG: (1.2e-09); PFAM: Polynucleotide adenylyltransferase region: (9.8e-31) metal-dependent phosphohydrolase, HD subdomain: (2.7e-17); KEGG: dra:DR1191 tRNA nucleotidyltransferase/poly A polymerase family protein, ev=1e-162, 70% identity YP_604085.1 PFAM: IS1 transposase: (1.4e-21); KEGG: sru:SRU_2704 ISSru3, transposase InsB, ev=4e-21, 41% identity YP_604086.1 PFAM: protein of unknown function DUF81: (7.8e-30); KEGG: dra:DR0544 hypothetical protein, ev=1e-124, 92% identity YP_604087.1 KEGG: dra:DR0545 hypothetical protein, ev=3e-28, 67% identity YP_604088.1 PFAM: Enoyl-CoA hydratase/isomerase: (8.7e-07) 3-hydroxyacyl-CoA dehydrogenase-like: (3.5e-10) 3-hydroxyacyl-CoA dehydrogenase, NAD-binding: (9.8e-57); KEGG: dra:DR2477 3-hydroxyacyl-CoA dehydrogenase, ev=0.0, 81% identity YP_604089.1 PFAM: Thiolase: (4.5e-110) 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal: (0.0025); KEGG: dra:DR2480 acetyl-CoA acetyltransferase, ev=0.0, 87% identity YP_604090.1 KEGG: dra:DR0049 hypothetical protein, ev=1e-164, 73% identity YP_604091.1 PFAM: Extracellular ligand-binding receptor: (1.2e-36); KEGG: tth:TTC0966 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, ev=6e-62, 38% identity YP_604092.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_604093.1 PFAM: protein of unknown function DUF299: (2.4e-81); KEGG: dra:DR1728 hypothetical protein, ev=1e-103, 71% identity YP_604094.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (4.1e-05) protein of unknown function DUF224, cysteine-rich region: (2.3e-20); KEGG: dra:DR1730 glycolate oxidase, iron-sulfur subunit, ev=0.0, 85% identity YP_604095.1 PFAM: FAD linked oxidase-like: (2.4e-89); KEGG: dra:DR1731 glycolate oxidase subunit GlcD, ev=0.0, 80% identity YP_604096.1 KEGG: dra:DR1732 glycolate oxidase subunit GlcE, ev=2e-88, 75% identity YP_604097.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase: (5e-117); KEGG: tth:TTC1744 lactate 2-monooxygenase, ev=1e-124, 56% identity YP_604098.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_604099.1 KEGG: rso:RS05070 hemagglutinin/hemolysin-related protein, ev=2e-60, 26% identity YP_604101.1 modulates transcription in response to the NADH/NAD(+) redox state YP_604102.1 PFAM: Sporulation related: (4.3e-13); KEGG: dra:DR0938 hypothetical protein, ev=5e-80, 47% identity YP_604103.1 PFAM: TPR repeat: (0.44) Tetratricopeptide TPR_4: (0.002) Tetratricopeptide TPR_2: (0.0002); SMART: Tetratricopeptide region: (0.029); KEGG: dra:DR0937 tetratricopeptide repeat family protein, ev=1e-151, 54% identity YP_604104.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_604105.1 KEGG: dra:DR0897 hypothetical protein, ev=2e-51, 63% identity YP_604106.1 KEGG: dra:DR0911 DNA-directed RNA polymerase, beta' subunit, ev=0.0, 88% identity; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime: (0); PFAM: RNA polymerase, alpha subunit: (3e-78) RNA polymerase Rpb1, domain 3: (5.4e-29) RNA polymerase Rpb1, domain 1: (8.2e-120) RNA polymerase Rpb1, domain 5: (4.2e-63) RNA polymerase Rpb1, domain 4: (1.3e-27); SMART: RNA polymerase I subunit A-like: (2.8e-161) YP_604107.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_604108.1 PFAM: Tetratricopeptide TPR_4: (0.025); KEGG: ccr:CC0483 hypothetical protein, ev=1e-24, 31% identity YP_604109.1 PFAM: Cold-shock protein, DNA-binding: (2.2e-34) Ribonuclease B, OB region-like: (0.0062); SMART: Cold shock protein: (1.9e-32); KEGG: dra:DR0907 cold shock protein, CSD family, ev=2e-38, 85% identity YP_604110.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_604111.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_604112.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_604113.1 binds directly to 23S ribosomal RNA YP_604114.1 KEGG: dra:DR2047 transcription antitermination protein NusG, ev=4e-91, 87% identity; TIGRFAM: transcription termination/antitermination factor NusG: (1.9e-69); PFAM: transcription antitermination protein NusG: (2.7e-45) KOW: (1.3e-09); SMART: NGN: (2.7e-49) KOW (Kyrpides, Ouzounis, Woese) motif: (2.3e-08) YP_604115.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_604116.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_604117.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_604118.1 PFAM: ABC transporter transmembrane region: (1.5e-28) ABC transporter related: (2.3e-57); SMART: ATPase: (7.2e-19); KEGG: dra:DR2051 ABC transporter ATP-binding protein, MDR family, ev=0.0, 75% identity YP_604119.1 PFAM: ABC transporter transmembrane region: (6.1e-32) ABC transporter related: (2.4e-54); SMART: ATPase: (3.6e-13); KEGG: dra:DR2052 ABC transporter ATP-binding protein, MsbA family, ev=0.0, 80% identity YP_604120.1 TIGRFAM: Periplasmic phosphate binding protein: (1.1e-107); PFAM: extracellular solute-binding protein, family 1: (1.1e-17); KEGG: dra:DRA0157 phosphate transport system substrate-binding protein, ev=1e-158, 83% identity YP_604121.1 TIGRFAM: Phosphate ABC transporter permease PstC: (5.1e-105); PFAM: binding-protein-dependent transport systems inner membrane component: (7.9e-21); KEGG: dra:DRA0158 phosphate transport system permease, ev=1e-153, 82% identity YP_604122.1 TIGRFAM: Phosphate transport system permease 2: (9.4e-105); PFAM: binding-protein-dependent transport systems inner membrane component: (1.2e-23); KEGG: dra:DRA0159 phosphate transport system permease, ev=1e-120, 79% identity YP_604123.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_604124.1 PFAM: PhoU: (2.6e-19); KEGG: dra:DR2053 phosphate transport system regulatory protein PhoU, , ev=5e-74, 75% identity YP_604125.1 PFAM: peptidase S49: (6.4e-43); KEGG: dra:DR2096 endopeptidase IV-related protein, ev=0.0, 76% identity YP_604126.1 PFAM: globin: (0.00013); KEGG: bms:BRA0898 hypothetical protein, ev=1e-13, 35% identity YP_604127.1 PFAM: cytochrome c, class I: (4.5e-09); KEGG: dra:DR2095 C-type cytochrome, , ev=1e-29, 33% identity YP_604128.1 PFAM: periplasmic binding protein: (8.6e-06); KEGG: dra:DR1373 metal binding protein, , ev=1e-97, 73% identity YP_604129.1 PFAM: regulatory protein, TetR: (2.5e-13); KEGG: betI; regulatory protein BetI, ev=4e-14, 35% identity YP_604130.1 PFAM: Cl- channel, voltage gated: (2.3e-07) TrkA-C: (6.9e-09); KEGG: dra:DR1752 hypothetical protein, ev=0.0, 63% identity YP_604131.1 PFAM: alpha amylase, catalytic region: (4.8e-71); SMART: Alpha amylase, catalytic subdomain: (3.1e-89); KEGG: dra:DR1472 glycosyl hydrolase, family 13, ev=0.0, 71% identity YP_604132.1 PFAM: phosphoenolpyruvate carboxylase: (1e-63); KEGG: dra:DR1283 phosphoenolpyruvate carboxylase, ev=0.0, 74% identity YP_604133.1 PFAM: metallophosphoesterase: (1.1e-10); KEGG: dra:DR1281 hypothetical protein, ev=1e-106, 71% identity YP_604134.1 KEGG: dra:DR0719 hypothetical protein, ev=3e-41, 40% identity; TIGRFAM: uncharacterized domain HDIG: (0.00096); PFAM: metal-dependent phosphohydrolase, HD subdomain: (5.1e-30) PAS fold: (0.0044); SMART: PAS: (4.7e-06) Metal-dependent phosphohydrolase, HD region: (1.3e-10) YP_604135.1 KEGG: dra:DR1388 hypothetical protein, ev=2e-52, 52% identity YP_604136.1 PFAM: cell wall hydrolase/autolysin: (1.4e-75); KEGG: dra:DR1387 N-acetylmuramoyl-L-alanine amidase, , ev=1e-96, 53% identity YP_604137.1 TIGRFAM: ATP: (4.1e-106); PFAM: cobalamin adenosyltransferase: (8.8e-91); KEGG: dra:DR1638 hypothetical protein, ev=1e-78, 77% identity YP_604138.1 amylomaltase; acts to release glucose from maltodextrins YP_604139.1 TIGRFAM: transcription elongation factor GreA: (5.2e-63); PFAM: transcription elongation factor GreA/GreB region: (3.1e-13); KEGG: dra:DR1162 transcription elongation factor, ev=1e-47, 62% identity YP_604140.1 KEGG: dra:DR1163 twitching motility protein, ev=1e-152, 74% identity; TIGRFAM: twitching motility protein: (4.5e-227); PFAM: type II secretion system protein E: (4.1e-20); SMART: ATPase: (7.8e-06) YP_604141.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_604142.1 PFAM: membrane protein of unknown function: (1.7e-50); KEGG: dra:DR1165 hypothetical protein, ev=2e-48, 79% identity YP_604143.1 PFAM: alpha amylase, catalytic region: (4.5e-114); SMART: Alpha amylase, catalytic subdomain: (4.1e-148); KEGG: dra:DR1375 alpha-glucosidase, ev=0.0, 77% identity YP_604144.1 PFAM: Septum formation inhibitor MinC: (2.7e-37); KEGG: dra:DR1753 septum site-determining protein, , ev=1e-53, 66% identity YP_604145.1 PFAM: RNA binding S1: (3.6e-22); KEGG: dra:DR1754 hypothetical protein, ev=8e-58, 89% identity YP_604146.1 proposed role in polysaccahride synthesis YP_604147.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap: (7.6e-17); SMART: PDZ/DHR/GLGF: (1.2e-11); KEGG: dra:DR1756 periplasmic serine protease Do, , ev=1e-154, 64% identity YP_604148.1 KEGG: dra:DR1421 hypothetical protein, ev=3e-24, 56% identity YP_604149.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate and N-acetyl-L-aminoadipate to form N-acetyl-L-aminoadipate 5-phosphate in arginine and lysine biosynthesis YP_604150.1 PFAM: major facilitator superfamily MFS_1: (9.1e-38); KEGG: nfa:nfa20550 transporter ev=6e-74, 46% identity YP_604151.1 PFAM: transposase, IS605 OrfB: (1.4e-26); KEGG: noc:Noc_2211 transposase, IS605 OrfB, ev=3e-36, 32% identity YP_604152.1 KEGG: dra:DR1844 hypothetical protein, ev=9e-23, 55% identity YP_604153.1 PFAM: protein of unknown function DUF84: (1.7e-32); KEGG: tko:TK1747 hypothetical protein, ev=4e-21, 38% identity YP_604154.1 KEGG: dra:DR0409 hypothetical protein, ev=7e-37, 60% identity YP_604155.1 PFAM: response regulator receiver: (5.3e-24); KEGG: dra:DR0408 response regulator, ev=2e-46, 65% identity YP_604156.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_604157.1 PFAM: glycoside hydrolase, family 20: (2.6e-09); KEGG: blo:BL0056 possible beta-hexosaminidase A, ev=1e-15, 23% identity YP_604158.1 PFAM: extracellular solute-binding protein, family 1: (2e-30); KEGG: cvi:CV2897 probable sugar ABC transporter periplasmic sugar-binding protein, ev=2e-69, 37% identity YP_604159.1 TIGRFAM: adenylosuccinate lyase: (2.6e-179); PFAM: fumarate lyase: (2e-49); KEGG: dra:DR2178 adenylosuccinate lyase, ev=0.0, 86% identity YP_604160.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (1.3e-06) HAD-superfamily hydrolase, subfamily IA, variant 1: (4.1e-05); PFAM: Haloacid dehalogenase-like hydrolase: (1.1e-33); KEGG: dra:DR0729 hydrolase, CbbY/CbbZ/GpH/YieH family, ev=2e-57, 55% identity YP_604161.1 PFAM: short-chain dehydrogenase/reductase SDR: (2.7e-16); KEGG: dra:DR0730 oxidoreductase, short-chain dehydrogenase/reductase family, ev=1e-110, 84% identity YP_604162.1 PFAM: Disulphide bond formation protein DsbB: (8.7e-25); KEGG: dra:DR0754 hypothetical protein, ev=9e-46, 60% identity YP_604163.1 PFAM: DSBA oxidoreductase: (6e-07); KEGG: dra:DR0753 hypothetical protein, ev=6e-72, 63% identity YP_604164.1 KEGG: dra:DR1770 hypothetical protein, ev=3e-49, 50% identity YP_604165.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_604166.1 PFAM: basic membrane lipoprotein: (6e-52); KEGG: dra:DR2070 membrane lipoprotein, ev=1e-166, 77% identity YP_604167.1 KEGG: dra:DR2069 DNA ligase, ev=0.0, 79% identity; TIGRFAM: DNA ligase, NAD-dependent: (0); PFAM: helix-hairpin-helix motif: (0.00049) BRCT: (6.6e-17) NAD-dependent DNA ligase: (8.3e-139) zinc-finger, NAD-dependent DNA ligase C4-type: (1.6e-13) NAD-dependent DNA ligase, OB-fold: (6.7e-49); SMART: Helix-hairpin-helix DNA-binding, class 1: (0.4) YP_604168.1 PFAM: protein of unknown function DUF322: (1.9e-31); KEGG: dra:DR2068 alkaline shock protein-related protein, ev=1e-37, 68% identity YP_604169.1 TIGRFAM: transcription antitermination factor NusB: (6.4e-35); PFAM: NusB/RsmB/TIM44: (3.8e-45); KEGG: dra:DR2067 N-utilization substance protein B, ev=2e-61, 76% identity YP_604170.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_604171.1 PFAM: acid phosphatase/vanadium-dependent haloperoxidase related: (2.5e-50); KEGG: dra:DR2066 hypothetical protein, ev=1e-59, 74% identity YP_604172.1 KEGG: dra:DR0727 hypothetical protein, ev=1e-49, 75% identity YP_604173.1 KEGG: dra:DR0202 hypothetical protein, ev=2e-17, 43% identity YP_604174.1 PFAM: basic membrane lipoprotein: (4.6e-36); KEGG: dra:DR2070 membrane lipoprotein, ev=2e-99, 50% identity YP_604175.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_604176.1 KEGG: dra:DR0384 hypothetical protein, ev=8e-37, 57% identity YP_604177.1 PFAM: peptidase M55, D-aminopeptidase: (3e-150); KEGG: dra:DR1843 peptide ABC transporter , ev=1e-122, 77% identity YP_604178.1 TIGRFAM: Phenylacetic acid degradation-related protein: (1.3e-25); PFAM: thioesterase superfamily: (2.8e-18); KEGG: dra:DR0847 ComA-related protein, ev=2e-53, 83% identity YP_604179.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_604180.1 TIGRFAM: NRAMP family Mn2+/Fe2+ transporters: (3e-128); PFAM: natural resistance-associated macrophage protein: (1.4e-159); KEGG: dra:DR1709 integral membrane protein, NRAMP family, ev=1e-175, 72% identity YP_604181.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_604182.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (2.4e-30) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (7.6e-14) FAD dependent oxidoreductase: (0.0003); KEGG: dra:DR0992 NADH oxidase, ev=1e-175, 70% identity YP_604183.1 KEGG: dra:DR0960 hypothetical protein, ev=2e-53, 40% identity YP_604184.1 PFAM: aminotransferase, class V: (9.8e-12); KEGG: dra:DR0991 aminotransferase, ev=1e-175, 80% identity YP_604185.1 PFAM: CBS: (3.5e-41); KEGG: dra:DR0990 acetoin utilization protein, , ev=6e-78, 71% identity YP_604186.1 PFAM: outer membrane chaperone Skp (OmpH): (2.2e-25); KEGG: dra:DR0989 cationic outer membrane protein OmpH, , ev=1e-47, 56% identity YP_604187.1 PFAM: outer membrane chaperone Skp (OmpH): (2.4e-30); KEGG: dra:DR0988 hypothetical protein, ev=5e-43, 55% identity YP_604188.1 PFAM: Carboxymuconolactone decarboxylase: (8.3e-26); KEGG: dra:DR0973 gamma-carboxymuconolactone decarboxylase, ev=3e-51, 83% identity YP_604189.1 KEGG: dra:DR0972 hypothetical protein, ev=2e-38, 42% identity YP_604190.1 PFAM: electron transfer flavoprotein beta-subunit: (1.5e-46); KEGG: dra:DR0971 electron transfer flavoprotein, beta subunit, ev=1e-117, 83% identity YP_604191.1 PFAM: electron transfer flavoprotein beta-subunit: (9.4e-20) electron transfer flavoprotein, alpha subunit: (4.5e-46); KEGG: dra:DR0970 electron transfer flavoprotein, alpha subunit, ev=1e-148, 86% identity YP_604192.1 KEGG: sco:SCO1048 secreted protein, ev=2e-10, 38% identity YP_604193.1 TIGRFAM: conserved hypothetical protein: (1.2e-151); PFAM: protein of unknown function UPF0052 and CofD: (3.5e-124); KEGG: dra:DR1435 conserved hypothetical protein, ev=1e-176, 72% identity YP_604194.1 PFAM: Uncharacterised P-loop ATPase UPF0042: (2e-83); KEGG: dra:DR1434 hypothetical protein, ev=1e-116, 76% identity YP_604195.1 TIGRFAM: methionyl-tRNA synthetase: (1.7e-151) methionyl-tRNA synthetase, beta subunit: (3.7e-47); PFAM: cysteinyl-tRNA synthetase, class Ia: (0.0074) t-RNA-binding region: (4.7e-43); KEGG: dra:DR1433 methionyl-tRNA synthetase, ev=0.0, 78% identity YP_604196.1 PFAM: glycoside hydrolase 15-related: (1.9e-32); KEGG: mlo:mlr4205 glucoamylase, (glucan 1,4-alpha-glucosidase), ev=1e-150, 42% identity YP_604197.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_604198.1 KEGG: dra:DR0061 hypothetical protein, ev=1e-60, 38% identity YP_604199.1 PFAM: protein kinase: (1.1e-57) NHL repeat: (0.058); SMART: Tyrosine protein kinase: (6.4e-16) Serine/threonine protein kinase: (7.7e-69); KEGG: dra:DR0058 serine/threonine protein kinase, , ev=0.0, 70% identity YP_604200.1 PFAM: glutaredoxin 2: (7.6e-20); KEGG: dra:DR0057 hypothetical protein, ev=7e-22, 65% identity YP_604201.1 KEGG: dra:DR2260 signal recognition particle-docking protein FtsY, ev=1e-149, 82% identity; TIGRFAM: signal recognition particle-docking protein FtsY: (1.5e-125); PFAM: GTP-binding signal recognition particle SRP54, G-domain: (2.7e-109); SMART: ATPase: (8.7e-14) YP_604202.1 PFAM: ABC transporter related: (3.2e-48); SMART: ATPase: (1.4e-11); KEGG: dra:DR2118 branched-chain amino acid transport system ATP-binding protein, ev=3e-98, 78% identity YP_604203.1 PFAM: ABC transporter related: (1e-55); SMART: ATPase: (1.7e-11); KEGG: dra:DR2119 branched-chain amino acid transport system ATP-binding protein, ev=1e-122, 86% identity YP_604204.1 PFAM: inner-membrane translocator: (2.6e-32); KEGG: dra:DR2120 branched-chain amino acid transport system permease, ev=1e-147, 84% identity YP_604205.1 PFAM: inner-membrane translocator: (9.2e-44); KEGG: dra:DR2121 branched-chain amino acid transport system permease, ev=1e-153, 83% identity YP_604206.1 PFAM: Extracellular ligand-binding receptor: (7.6e-53); KEGG: dra:DR2122 branched-chain amino acid transport system substrate-binding protein, ev=1e-160, 73% identity YP_604207.1 PFAM: acyl-CoA dehydrogenase-like: (3.1e-75) Acyl-CoA dehydrogenase, type 2-like: (1.9e-25); KEGG: dra:DR1318 acyl-CoA dehydrogenase, ev=0.0, 89% identity YP_604208.1 PFAM: GCN5-related N-acetyltransferase: (1.9e-11); KEGG: dra:DRA0062 acetyltransferase, , ev=1e-51, 55% identity YP_604209.1 PFAM: major facilitator superfamily MFS_1: (1.1e-51); KEGG: mag:amb2887 permease of the major facilitator superfamily, ev=1e-102, 47% identity YP_604210.1 PFAM: Methicillin resistance protein: (0.0002); KEGG: dra:DR1062 FemA-related protein, ev=1e-164, 76% identity YP_604211.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase: (6.4e-25); KEGG: dra:DR1063 peptidyl-prolyl cis-trans isomerase C, ev=1e-113, 62% identity YP_604212.1 KEGG: dra:DRA0140 hypothetical protein, ev=2e-40, 43% identity YP_604213.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_604214.1 KEGG: dra:DR1242 hypothetical protein, ev=3e-58, 65% identity YP_604215.1 PFAM: protein kinase: (2.2e-14); SMART: Tyrosine protein kinase: (4.4e-10) Serine/threonine protein kinase: (6e-21); KEGG: dra:DR1243 serine/threonine protein kinase, , ev=2e-89, 61% identity YP_604216.1 TIGRFAM: DNA polymerase III, delta subunit: (2e-46); PFAM: DNA polymerase III, delta: (1.5e-61); KEGG: dra:DR1244 DNA polymerase III, delta subunit, ev=1e-122, 72% identity YP_604217.1 KEGG: ttj:TTHA1712 hypothetical protein, ev=7e-11, 36% identity YP_604218.1 PFAM: DSBA oxidoreductase: (9e-08); KEGG: dra:DR2019 hypothetical protein, ev=2e-78, 49% identity YP_604219.1 PFAM: Amylo-alpha-1,6-glucosidase: (7.4e-06); KEGG: reu:Reut_A0692 amylo-alpha-1,6-glucosidase, ev=1e-99, 40% identity YP_604220.1 PFAM: binding-protein-dependent transport systems inner membrane component: (8.2e-13); KEGG: sme:SMa1362 inner-membrane permease, ev=2e-80, 37% identity YP_604221.1 PFAM: binding-protein-dependent transport systems inner membrane component: (0.0033); KEGG: sme:SMa1363 ABC transporter permease, ev=7e-78, 45% identity YP_604222.1 PFAM: extracellular solute-binding protein, family 1: (1.1e-28); KEGG: sme:SMa1364 ABC transporter periplasmic solute-binding protein, ev=9e-93, 44% identity YP_604223.1 PFAM: regulatory protein, LacI: (7.6e-11) periplasmic binding protein/LacI transcriptional regulator: (6e-05); KEGG: sma:SAV554 LacI-family transcriptional regulator, ev=3e-33, 35% identity YP_604224.1 PFAM: Alcohol dehydrogenase, zinc-binding: (6.9e-35) Alcohol dehydrogenase GroES-like: (3.1e-27); KEGG: dra:DR1061 NADPH quinone oxidoreductase, , ev=1e-134, 73% identity YP_604225.1 PFAM: Enoyl-CoA hydratase/isomerase: (2.2e-60) 3-hydroxyacyl-CoA dehydrogenase-like: (0.00023) 3-hydroxyacyl-CoA dehydrogenase, NAD-binding: (5.1e-93); KEGG: dra:DR1487 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase, ev=0.0, 80% identity YP_604226.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_604227.1 PFAM: low molecular weight phosphotyrosine protein phosphatase: (1e-30); KEGG: dra:DRA0123 arsenate reductase, ev=2e-61, 76% identity YP_604228.1 PFAM: type II secretion system protein: (2.3e-14); KEGG: dra:DR1863 pilin biogenesis protein, ev=0.0, 82% identity YP_604229.1 TIGRFAM: Sua5/YciO/YrdC/YwlC: (4.2e-32); PFAM: SUA5/yciO/yrdC-like: (4.9e-45); KEGG: dra:DR1862 SUA5-related protein, ev=9e-39, 51% identity YP_604230.1 PFAM: chromosome segregation and condensation protein ScpB: (1.2e-69); KEGG: dra:DR1861 segregation and condensation protein B, ev=3e-72, 81% identity YP_604231.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_604232.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_604233.1 KEGG: dra:DR0895 hypothetical protein, ev=1e-26, 53% identity YP_604234.1 TIGRFAM: Pseudouridine synthase, Rsu: (7.6e-55); PFAM: RNA-binding S4: (2.3e-13) pseudouridine synthase: (3.5e-11); KEGG: dra:DR0896 ribosomal large subunit pseudouridine synthase B, ev=2e-98, 72% identity YP_604235.1 PFAM: protein of unknown function DUF423: (8.9e-41); KEGG: dra:DR1864 hypothetical protein, ev=4e-35, 69% identity YP_604236.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_604237.1 PFAM: methyltransferase: (3.7e-131); KEGG: dra:DR1866 S-adenosyl-methyltransferase, ev=1e-124, 77% identity YP_604238.1 KEGG: dra:DR1867 hypothetical protein, ev=2e-21, 48% identity YP_604239.1 PFAM: penicillin-binding protein, transpeptidase: (5.9e-72); KEGG: dra:DR1868 penicillin-binding protein 2, ev=1e-153, 62% identity YP_604241.1 KEGG: dra:DR0488 hypothetical protein, ev=2e-38, 52% identity YP_604242.1 KEGG: dra:DR1895 alanine dehydrogenase, ev=1e-173, 81% identity; TIGRFAM: alanine dehydrogenase: (9.1e-178); PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding: (0.0025) alanine dehydrogenase/PNT-like: (1.9e-88) YP_604243.1 PFAM: regulatory proteins, AsnC/Lrp: (2.1e-29); KEGG: dra:DR1894 transcriptional regulator, AsnC family, ev=2e-70, 88% identity YP_604244.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type: (8e-27); KEGG: dra:DR1893 peptidyl-prolyl cis-trans isomerase, cyclophilin-type, ev=1e-52, 53% identity YP_604245.1 PFAM: LrgB-like protein: (1.3e-75); KEGG: dra:DR1449 hypothetical protein, ev=2e-78, 70% identity YP_604246.1 PFAM: LrgA: (7.7e-35); KEGG: dra:DR1450 holin-like protein, ev=2e-42, 74% identity YP_604247.1 PFAM: purine and other phosphorylases, family 1: (1.1e-60); KEGG: dra:DR1451 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase, ev=2e-97, 78% identity YP_604248.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (5.7e-08); KEGG: dra:DR2330 ferredoxin, ev=6e-38, 88% identity YP_604250.1 PFAM: globin: (0.00059); KEGG: bme:BMEII0398 SEC-independent protein translocase TatC, ev=1e-15, 33% identity YP_604251.1 PFAM: cyclic nucleotide-binding: (1.1e-15); SMART: regulatory protein, Crp: (7.6e-08); KEGG: dvu:DVU2547 transcriptional regulator, , ev=1e-22, 33% identity YP_604252.1 PFAM: aminotransferase, class I and II: (1.2e-16); KEGG: dra:DR1452 aminotransferase, class I, ev=1e-157, 67% identity YP_604253.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_604254.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_604255.1 KEGG: dra:DR1166 hypothetical protein, ev=4e-52, 58% identity YP_604256.1 SMART: HhH-GPD: (1.2e-11); KEGG: dra:DR0928 endonuclease III, , ev=8e-61, 48% identity YP_604257.1 PFAM: t-RNA-binding region: (5.7e-07); KEGG: rsp:RSP_3365 protein secretion chaperonine, ev=2e-18, 46% identity YP_604258.1 PFAM: Integral membrane protein TerC: (6.9e-46); KEGG: dra:DRB0131 hypothetical protein, ev=1e-104, 75% identity YP_604259.1 PFAM: regulatory protein, TetR: (1e-19); KEGG: dra:DR2148 transcriptional regulator, TetR family, ev=2e-76, 75% identity YP_604260.1 KEGG: ttj:TTHA1478 hypothetical protein, ev=6e-23, 41% identity YP_604261.1 TIGRFAM: diaminopimelate decarboxylase: (8.5e-157); PFAM: Orn/DAP/Arg decarboxylase 2: (5.3e-33); KEGG: dra:DR1758 diaminopimelate decarboxylase, ev=1e-150, 70% identity YP_604263.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_604264.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding: (6.3e-67); KEGG: dra:DR1701 2-hydroxyacid dehydrogenase, , ev=1e-106, 64% identity YP_604265.1 PFAM: GCN5-related N-acetyltransferase: (6.9e-13); KEGG: dra:DR1702 kanamycin resistance protein-related protein, ev=2e-68, 72% identity YP_604266.1 PFAM: inositol monophosphatase: (1.3e-74); KEGG: dra:DR1703 inositol monophosphatase family protein, ev=1e-123, 69% identity YP_604267.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_604268.1 TIGRFAM: GGDEF domain: (2.1e-48); PFAM: GGDEF: (5.7e-66); KEGG: tth:TTC0402 hypothetical protein, ev=4e-34, 41% identity YP_604269.1 KEGG: dra:DR1053 hydrolase, , ev=2e-81, 70% identity YP_604270.1 PFAM: ABC transporter related: (3.3e-49); SMART: ATPase: (9e-10); KEGG: ttj:TTHA0694 branched-chain amino acid ABC transporter ATP-binding protein, ev=2e-69, 59% identity YP_604271.1 PFAM: ABC transporter related: (2e-48); SMART: ATPase: (9e-13); KEGG: tth:TTC0335 branched-chain amino acid transport ATP-binding protein livG, ev=5e-76, 64% identity YP_604272.1 PFAM: inner-membrane translocator: (6.6e-30); KEGG: tth:TTC0336 branched amino acid transport system permease, ev=3e-72, 51% identity YP_604273.1 PFAM: inner-membrane translocator: (1.7e-38); KEGG: tth:TTC0337 branched-chain amino acid transport system permease livH, ev=2e-86, 59% identity YP_604274.1 PFAM: alpha/beta hydrolase fold: (4.1e-12); KEGG: sth:STH2847 hypothetical protein, ev=1e-116, 59% identity YP_604276.1 PFAM: IS1 transposase: (7.4e-22); KEGG: sru:SRU_2704 ISSru3, transposase InsB, ev=1e-21, 41% identity YP_604277.1 KEGG: tth:TTC0338 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, ev=1e-37, 51% identity YP_604278.1 PFAM: alpha/beta hydrolase fold: (0.00013); KEGG: bat:BAS4629 homoserine O-acetyltransferase, , ev=6e-36, 40% identity YP_604279.1 KEGG: dra:DRA0068 3-oxoacid CoA-transferase subunit A, ev=1e-116, 89% identity; TIGRFAM: 3-oxoacid CoA-transferase, subunit A: (6.8e-97); PFAM: coenzyme A transferase: (4.1e-108) YP_604280.1 KEGG: dra:DRA0067 3-oxoacid CoA-transferase subunit B, ev=1e-106, 93% identity; TIGRFAM: 3-oxoacid CoA-transferase, subunit B: (5e-162); PFAM: coenzyme A transferase: (2.1e-63) YP_604281.1 PFAM: cytochrome c, class I: (5.4e-15); KEGG: ttj:TTHA1423 cytochrome c-552 precursor, ev=6e-37, 58% identity YP_604282.1 PFAM: carboxyl transferase: (3e-166); KEGG: dra:DR1542 propionyl-CoA carboxylase beta chain, ev=0.0, 87% identity YP_604283.1 PFAM: acyl-CoA dehydrogenase-like: (1.9e-61) Acyl-CoA dehydrogenase, type 2-like: (3.2e-26); KEGG: dra:DR1544 acyl-CoA dehydrogenase, ev=0.0, 83% identity YP_604284.1 PFAM: protein of unknown function DUF214: (5.7e-49); KEGG: dra:DR0487 lipoprotein releasing system transmembrane protein, ev=1e-162, 77% identity YP_604285.1 PFAM: PEGA: (1.8e-20); KEGG: dra:DR1185 S-layer-like array-related protein, ev=1e-138, 71% identity YP_604286.1 PFAM: NUDIX hydrolase: (5e-20); KEGG: dra:DR1184 MutT/NUDIX family protein, ev=3e-75, 73% identity YP_604287.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_604288.1 KEGG: dra:DR1465 hypothetical protein, ev=2e-35, 53% identity YP_604289.1 PFAM: short-chain dehydrogenase/reductase SDR: (1.7e-33); KEGG: dra:DR1467 short chain dehydrogenase, ev=2e-98, 75% identity YP_604290.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_604291.1 PFAM: cell wall hydrolase/autolysin: (2.3e-05); KEGG: dra:DR1469 hypothetical protein, ev=1e-164, 66% identity YP_604292.1 KEGG: dra:DR1470 hypothetical protein, ev=2e-61, 64% identity YP_604293.1 PFAM: SMC protein-like: (4e-62) SMCs flexible hinge: (4.8e-28); KEGG: dra:DR1471 Smc1/Cut3/Cut14 family protein, ev=0.0, 70% identity YP_604294.1 PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity YP_604295.1 TIGRFAM: nuclease SbcCD, D subunit: (2.7e-46); PFAM: metallophosphoesterase: (1e-21); KEGG: dra:DR1921 exonuclease SbcD, , ev=1e-165, 74% identity YP_604297.1 TIGRFAM: Helicase RecD/TraA: (0); KEGG: dra:DR1902 exodeoxyribonuclease V, subunit RecD, , ev=0.0, 81% identity YP_604298.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_604299.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_604300.1 PFAM: TPR repeat: (0.066) Tetratricopeptide TPR_3: (1) Tetratricopeptide TPR_2: (0.0053); SMART: Tetratricopeptide region: (0.41); KEGG: dra:DR1891 tetratricopeptide repeat family protein, ev=1e-141, 66% identity YP_604301.1 PFAM: manganese and iron superoxide dismutase: (4.2e-54); KEGG: dra:DR1279 superoxide dismutase (sodA), Mn family, ev=1e-101, 84% identity YP_604302.1 PFAM: protein of unknown function DUF112, transmembrane: (7.5e-202); KEGG: bja:blr3163 hypothetical protein, ev=0.0, 66% identity YP_604303.1 KEGG: sco:SCO1139 integral membrane protein, ev=4e-17, 34% identity YP_604304.1 PFAM: Uncharacterized protein UPF0065: (1.6e-21); KEGG: sme:SMb20724 tricarboxylic transport membrane protein, ev=7e-92, 57% identity YP_604305.1 PFAM: ATP-binding region, ATPase-like: (4.7e-27); KEGG: bha:BH3839 two-component sensor histidine kinase, ev=1e-73, 35% identity YP_604306.1 PFAM: response regulator receiver: (8.7e-27); KEGG: vvy:VV1604 response regulator of citrate/malate metabolism, ev=4e-38, 40% identity YP_604307.1 KEGG: dra:DR1139 hypothetical protein, ev=2e-44, 71% identity YP_604308.1 KEGG: dra:DR1140 hypothetical protein, ev=2e-37, 63% identity YP_604309.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_604310.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_604312.1 KEGG: dra:DR1522 pyrroline-5-carboxylate reductase, ev=1e-107, 76% identity; TIGRFAM: pyrroline-5-carboxylate reductase: (4.5e-75); PFAM: NADP oxidoreductase, coenzyme F420-dependent: (1.3e-56) YP_604313.1 PFAM: protein of unknown function DUF81: (7e-26); KEGG: dra:DR1858 hypothetical protein, ev=1e-118, 86% identity YP_604314.1 KEGG: dra:DR1849 peptide methionine sulfoxide reductase, ev=2e-75, 68% identity; TIGRFAM: peptide methionine sulfoxide reductase: (4.1e-80); PFAM: Methionine sulfoxide reductase A: (1.3e-84) YP_604315.1 PFAM: transposase, IS4: (4.7e-07); KEGG: lil:LA3155 transposase, ev=7e-15, 28% identity YP_604317.1 PFAM: MOSC: (1.1e-45); KEGG: dra:DR1883 hypothetical protein, ev=1e-82, 69% identity YP_604318.1 PFAM: phosphoribosyltransferase: (2e-05); KEGG: dra:DR0568 adenine phosphoribosyltransferase, ev=2e-75, 81% identity YP_604319.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_604320.1 PFAM: amine oxidase: (0.0005) FAD dependent oxidoreductase: (0.00012); KEGG: dra:DR0810 dehydrogenase, , ev=1e-165, 67% identity YP_604321.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_604322.1 PFAM: Proline dehydrogenase: (4.3e-56); KEGG: dra:DR0814 proline dehydrogenase, , ev=1e-132, 74% identity YP_604323.1 PFAM: regulatory protein GntR, HTH: (2.3e-21) GntR-like: (4.1e-23); KEGG: dra:DR0815 transcriptional regulator, GntR family, ev=3e-87, 77% identity YP_604324.1 KEGG: dra:DR0816 Mg(2+) transport ATPase-related protein, ev=2e-24, 58% identity YP_604326.1 TIGRFAM: DNA repair protein RecO: (2e-06); PFAM: Recombination protein O, RecO: (8.5e-07); KEGG: dra:DR0819 hypothetical protein, ev=1e-109, 80% identity YP_604327.1 PFAM: Alpha/beta hydrolase fold-3: (9.4e-10); KEGG: dra:DR0821 lipase, , ev=1e-116, 70% identity YP_604328.1 TIGRFAM: Lycopene cyclase, beta and epsilon: (5.7e-141); PFAM: Lycopene beta and epsilon cyclase: (2.9e-45); KEGG: dra:DR0801 lycopene cyclase, ev=1e-130, 61% identity YP_604330.1 PFAM: heat shock protein Hsp20: (1.5e-05); KEGG: dra:DR1691 heat shock protein-related protein, ev=2e-40, 65% identity YP_604331.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_604332.1 KEGG: dra:DR1689 glucose-1-phosphate adenylyltransferase, ev=0.0, 85% identity; TIGRFAM: Glucose-1-phosphate adenylyltransferase: (2.7e-248); PFAM: Nucleotidyl transferase: (2.3e-75) YP_604333.1 KEGG: dra:DR1189 methylmalonyl-CoA mutase, alpha subunit, chain A, ev=0.0, 91% identity; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain: (8.1e-224); PFAM: methylmalonyl-CoA mutase: (1.8e-235) YP_604334.1 TIGRFAM: Peptidase C56, PfpI: (3.4e-51); PFAM: ThiJ/PfpI: (1.3e-49); KEGG: dra:DR1199 protease I, ev=2e-83, 80% identity YP_604335.1 TIGRFAM: Small GTP-binding protein domain: (3.4e-21) GTP-binding protein TypA: (0); PFAM: elongation factor G-like: (4.5e-28) protein synthesis factor, GTP-binding: (2.5e-67) elongation factor Tu, domain 2: (1.1e-15); KEGG: dra:DR1198 GTP-binding elongation factor family protein TypA/BipA, ev=0.0, 91% identity YP_604336.1 KEGG: dra:DR1195 hypothetical protein, ev=9e-52, 46% identity YP_604338.1 TIGRFAM: cation diffusion facilitator family transporter: (1.3e-67); PFAM: cation efflux protein: (4e-97); KEGG: dra:DR1236 hypothetical protein, ev=1e-112, 72% identity YP_604339.1 PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity YP_604340.1 PFAM: leucine rich repeat variant: (0.00037); KEGG: dra:DR1773 hypothetical protein, ev=1e-164, 71% identity YP_604341.1 PFAM: metallophosphoesterase: (1.6e-13); KEGG: dra:DRA0124 hypothetical protein, ev=8e-54, 50% identity YP_604342.1 KEGG: dra:DR1169 hypothetical protein, ev=0.0, 84% identity YP_604343.1 PFAM: ATPase associated with various cellular activities, AAA_3: (2.1e-06) ATPase associated with various cellular activities, AAA_5: (0.00021); KEGG: dra:DR1171 hypothetical protein, ev=1e-171, 85% identity YP_604344.1 KEGG: dra:DR2566 hypothetical protein, ev=2e-26, 65% identity YP_604345.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (0.00049) protein of unknown function DUF224, cysteine-rich region: (2e-06); KEGG: dra:DR2565 iron-sulfur binding reductase, , ev=0.0, 68% identity YP_604346.1 KEGG: dra:DR1200 hypothetical protein, ev=1e-83, 66% identity YP_604347.1 PFAM: Tetratricopeptide TPR_4: (0.049) Tetratricopeptide TPR_2: (0.00068); KEGG: dra:DR1201 hypothetical protein, ev=0.0, 57% identity YP_604348.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_604349.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_604350.1 KEGG: dra:DR2156 hypothetical protein, ev=1e-44, 71% identity YP_604351.1 KEGG: dra:DR2157 hypothetical protein, ev=9e-14, 57% identity YP_604352.1 KEGG: dra:DR2158 hypothetical protein, ev=6e-10, 52% identity YP_604353.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_604354.1 PFAM: Dual specificity protein phosphatase: (0.00064); SMART: Protein tyrosine phosphatase, catalytic region: (1.2e-09); KEGG: dra:DR2161 protein-tyrosine phosphatase-related protein, ev=4e-57, 62% identity YP_604355.1 PFAM: Antibiotic biosynthesis monooxygenase: (2.2e-20); KEGG: dra:DR0446 hypothetical protein, ev=1e-32, 62% identity YP_604356.1 KEGG: dra:DR1180 hypothetical protein, ev=1e-31, 46% identity YP_604357.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_604358.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_604359.1 PFAM: succinate dehydrogenase, cytochrome b subunit: (1e-05); KEGG: dra:DR0953 succinate dehydrogenase hydrophobic membrane anchor protein, ev=2e-57, 82% identity YP_604360.1 PFAM: succinate dehydrogenase, cytochrome b subunit: (3.2e-06); KEGG: dra:DR0954 succinate dehydrogenase cytochrome b-556 subunit, ev=8e-48, 76% identity YP_604362.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding: (6.3e-07); KEGG: dra:DR1146 general stress protein 26, , ev=3e-54, 58% identity YP_604363.1 PFAM: major facilitator superfamily MFS_1: (1.4e-21); KEGG: dra:DR1056 hypothetical protein, ev=1e-161, 68% identity YP_604364.1 KEGG: dra:DR1218 hypothetical protein, ev=2e-29, 72% identity YP_604365.1 TIGRFAM: ferrous iron transport protein B: (8.9e-190) Small GTP-binding protein domain: (4.3e-09) GTP-binding: (3.4e-09); PFAM: GTP-binding protein, HSR1-related: (5.6e-36) Ferrous iron transport protein B-like: (1.1e-43) Ferrous iron transport B-like: (1.7e-17) nucleoside recognition: (4.5e-14); KEGG: dra:DR1219 ferrous iron transport protein B, ev=0.0, 80% identity YP_604366.1 PFAM: FeoA: (5.6e-23); KEGG: dra:DR1220 ferrous iron transport protein A, ev=1e-25, 76% identity YP_604367.1 PFAM: pseudouridine synthase: (3.7e-28); KEGG: dra:DR0961 ribosomal large subunit pseudouridine synthase, Rlu family, ev=1e-118, 82% identity YP_604369.1 PFAM: NAD-dependent epimerase/dehydratase: (3.6e-19) 3-beta hydroxysteroid dehydrogenase/isomerase: (2e-12) dTDP-4-dehydrorhamnose reductase: (2.9e-07) NmrA-like: (0.00014) Male sterility-like: (1.5e-07); KEGG: dra:DR1980 NADH dehydrogenase (ubiquinone), ev=1e-102, 63% identity YP_604370.1 KEGG: dra:DR1976 DNA mismatch repair protein MutS, , ev=0.0, 82% identity; TIGRFAM: MutS2 family protein: (1.6e-163); PFAM: DNA mismatch repair protein MutS-like: (2.4e-17) Smr protein/MutS2: (5.2e-29); SMART: MutS III: (8.6e-09) YP_604372.1 PFAM: major facilitator superfamily MFS_1: (6.7e-15); KEGG: dra:DR1971 hypothetical protein, ev=5e-93, 52% identity YP_604373.1 PFAM: transcription elongation factor GreA/GreB region: (2.7e-08); KEGG: dra:DR1970 transcription elongation factor, ev=2e-64, 79% identity YP_604374.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_604375.1 PFAM: ROK: (2e-32); KEGG: sma:SAV2248 ROK-family transcriptional regulator, ev=6e-60, 39% identity YP_604376.1 PFAM: extracellular solute-binding protein, family 1: (2.6e-16); KEGG: ttj:TTHA0688 sugar ABC transporter substrate-binding protein, ev=1e-176, 68% identity YP_604377.1 PFAM: binding-protein-dependent transport systems inner membrane component: (2.2e-11); KEGG: tth:TTC0327 glucose transport system permease, ev=1e-127, 60% identity YP_604378.1 PFAM: binding-protein-dependent transport systems inner membrane component: (5.7e-19); KEGG: ttj:TTHA0685 sugar ABC transporter permease, ev=1e-108, 71% identity YP_604379.1 PFAM: ATP-binding region, ATPase-like: (2.8e-40) histidine kinase A-like: (3.8e-13); KEGG: dra:DR0860 sensor histidine kinase, ev=1e-134, 65% identity YP_604380.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3: (2.9e-37); KEGG: dra:DR1506 NADH dehydrogenase I, A subunit, ev=3e-46, 83% identity YP_604381.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_604382.1 TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C: (5.6e-46); PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit: (2.3e-36); KEGG: dra:DR1504 NADH dehydrogenase I, C subunit, ev=1e-76, 65% identity YP_604383.1 KEGG: dra:DR1503 NADH dehydrogenase I, D subunit, ev=0.0, 86% identity; TIGRFAM: NADH dehydrogenase I, D subunit: (1.5e-271); PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa: (3.9e-119) YP_604384.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit: (7.3e-84); PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit: (4.8e-67); KEGG: dra:DR1501 NADH dehydrogenase I, E subunit, ev=7e-86, 79% identity YP_604385.1 KEGG: dra:DR1500 NADH dehydrogenase I, F subunit, ev=0.0, 85% identity; TIGRFAM: NADH-quinone oxidoreductase, F subunit: (8.3e-243); PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit: (8.4e-169) YP_604386.1 TIGRFAM: NADH-quinone oxidoreductase, chain G: (1e-244); PFAM: ferredoxin: (2.3e-10) molybdopterin oxidoreductase: (8e-11) molybdopterin oxidoreductase Fe4S4 region: (4.8e-08); KEGG: dra:DR1499 NADH dehydrogenase I, G subunit, ev=0.0, 72% identity YP_604387.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1: (5.5e-127); KEGG: dra:DR1498 NADH dehydrogenase I, H subunit, ev=1e-178, 80% identity YP_604388.1 TIGRFAM: NADH-quinone oxidoreductase, chain I: (4.3e-78); PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (1.9e-08); KEGG: dra:DR1497 NADH dehydrogenase I, I subunit, ev=5e-92, 90% identity YP_604389.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6: (4.5e-33); KEGG: dra:DR1496 NADH dehydrogenase I, J subunit, ev=1e-69, 73% identity YP_604390.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L: (2e-32); KEGG: dra:DR1495 NADH dehydrogenase I, K subunit, ev=7e-41, 85% identity YP_604391.1 KEGG: dra:DR1494 NADH dehydrogenase I, L subunit, ev=0.0, 79% identity; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L: (7.9e-225); PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L-like: (1.8e-17) NADH/Ubiquinone/plastoquinone (complex I): (8.2e-90) YP_604392.1 KEGG: dra:DR1493 NADH dehydrogenase I, M subunit, ev=0.0, 79% identity; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M: (9.9e-195); PFAM: NADH/Ubiquinone/plastoquinone (complex I): (3.7e-55) YP_604393.1 KEGG: dra:DR1492 NADH dehydrogenase I, N subunit, ev=0.0, 71% identity; TIGRFAM: Proton-translocating NADH-quinone oxidoreductase, chain N: (3e-174); PFAM: NADH/Ubiquinone/plastoquinone (complex I): (1.2e-65) YP_604394.1 KEGG: cte:CT1161 type III restriction system endonuclease, , ev=0.0, 82% identity YP_604395.1 KEGG: cte:CT1160 type III restriction system endonuclease, , ev=1e-20, 39% identity YP_604396.1 PFAM: transposase, IS4: (0.00017); KEGG: tth:TTC1433 hypothetical protein, ev=5e-31, 33% identity YP_604397.1 PFAM: Eco57I restriction endonuclease: (1.3e-53); KEGG: cte:CT1160 type III restriction system endonuclease, , ev=1e-138, 75% identity YP_604398.1 KEGG: cte:CT1159 type III restriction system methylase, ev=8e-94, 77% identity YP_604399.1 PFAM: transposase, IS891/IS1136/IS1341: (0.00029) transposase, IS605 OrfB: (8.4e-26); KEGG: tma:TM0135 transposase, , ev=4e-73, 39% identity YP_604400.1 PFAM: ABC transporter related: (8.7e-42); SMART: ATPase: (4.7e-19); KEGG: dra:DR1635 ABC transporter ATP-binding protein, EF-3 family, ev=0.0, 79% identity YP_604401.1 PFAM: toxic anion resistance: (5.3e-110); KEGG: dra:DR1127 hypothetical protein, ev=1e-180, 80% identity YP_604402.1 KEGG: dra:DR1138 hypothetical protein, ev=3e-31, 54% identity YP_604403.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_604404.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_604405.1 KEGG: dra:DR1607 hypothetical protein, ev=5e-37, 59% identity YP_604407.1 KEGG: dra:DRA0215 hypothetical protein, ev=4e-35, 63% identity YP_604408.1 KEGG: dra:DR1389 competence protein ComF, , ev=2e-72, 65% identity YP_604409.1 KEGG: dra:DR1320 hypothetical protein, ev=3e-42, 55% identity YP_604410.1 KEGG: dra:DR1425 hypothetical protein, ev=2e-41, 49% identity YP_604411.1 PFAM: dienelactone hydrolase: (0.0002) phospholipase/Carboxylesterase: (6.8e-16) Glyoxalase/bleomycin resistance protein/dioxygenase: (2.2e-08); KEGG: bja:bll3247 dioxygenase, ev=2e-81, 52% identity YP_604412.1 PFAM: regulatory protein, MarR: (5.6e-23); KEGG: gvi:glr1822 MarR family transcriptional regulatory protein, ev=1e-36, 54% identity YP_604413.1 KEGG: dra:DR1579 hypothetical protein, ev=0.0, 77% identity YP_604414.1 PFAM: cytochrome P450: (2.1e-07); KEGG: sco:SCO3636 cytochrome P-450 hydroxylase, ev=2e-96, 49% identity YP_604415.1 PFAM: protein of unknown function DUF88: (2.2e-75); KEGG: dra:DR1578 hypothetical protein, ev=2e-87, 89% identity YP_604416.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_604417.1 PFAM: bifunctional deaminase-reductase-like: (7.2e-33); KEGG: bce:BC3158 pyrimidine reductase, ev=5e-56, 56% identity YP_604418.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F: (5.5e-189); KEGG: dra:DR1659 oligopeptidase A, ev=0.0, 76% identity YP_604419.1 KEGG: dra:DR1602 hypothetical protein, ev=1e-158, 72% identity YP_604420.1 KEGG: dra:DR1603 hypothetical protein, ev=1e-120, 68% identity YP_604421.1 PFAM: polysaccharide deacetylase: (2.5e-45); KEGG: dra:DR1604 oligosaccharide deacetylase, , ev=1e-148, 68% identity YP_604422.1 PFAM: NAD-dependent epimerase/dehydratase: (0.0011) short-chain dehydrogenase/reductase SDR: (5.5e-22); KEGG: ttj:TTHA0693 3-hydroxybutyrate dehydrogenase, ev=1e-69, 58% identity YP_604423.1 PFAM: beta-lactamase: (5e-46); KEGG: mma:MM3157 6-aminohexanoate-dimer hydrolase, ev=1e-46, 37% identity YP_604424.1 PFAM: TPR repeat: (0.13); SMART: Tetratricopeptide region: (0.24); KEGG: sth:STH810 transcriptional regulator, ev=2e-87, 32% identity YP_604425.1 PFAM: Chromate transporter: (6.5e-07); KEGG: rpa:RPA3497 possible chromate transporter related to ChrA, ev=2e-23, 38% identity YP_604426.1 PFAM: Chromate transporter: (3.7e-08); KEGG: rso:RSc0979 probable transmembrane protein, ev=1e-20, 34% identity YP_604427.1 TIGRFAM: CRISPR-associated protein APE2256: (1.4e-30); KEGG: chy:CHY_2123 CRISPR-associated protein, ev=3e-18, 30% identity YP_604428.1 TIGRFAM: CRISPR-associated protein, TM1812: (2.1e-08) CRISPR-associated protein DxTHG: (0.00017); KEGG: chy:CHY_2124 hypothetical protein, ev=1e-17, 23% identity YP_604429.1 TIGRFAM: CRISPR-associated protein, TM1791: (1.4e-32); PFAM: protein of unknown function DUF324: (3.3e-12); KEGG: ttj:TTHB165 hypothetical protein, ev=9e-32, 39% identity YP_604430.1 TIGRFAM: CRISPR-associated protein, TM1791.1: (0.00088) YP_604431.1 TIGRFAM: CRISPR-associated RAMP Cmr4: (1e-69); PFAM: protein of unknown function DUF324: (8.3e-47); KEGG: hypothetical protein, ev=7e-47, 45% identity YP_604432.1 KEGG: hypothetical protein, ev=7e-39, 34% identity YP_604433.1 TIGRFAM: CRISPR-associated protein Crm2: (1.9e-23); KEGG: ttj:TTHB160 hypothetical protein, ev=5e-32, 40% identity YP_604434.1 TIGRFAM: CRISPR-associated protein TM1795 family-like: (7.2e-20); PFAM: protein of unknown function DUF324: (3.5e-11); KEGG: bha:BH0327 hypothetical protein, ev=6e-30, 29% identity YP_604435.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase: (1.7e-91); KEGG: dra:DR2190 NADH-dependent flavin oxidoreductase, , ev=1e-159, 74% identity YP_604436.1 PFAM: ABC transporter related: (7.4e-57); SMART: ATPase: (1.8e-19); KEGG: dra:DR2192 ABC transporter ATP-binding protein, ev=2e-84, 73% identity YP_604437.1 PFAM: cyclic nucleotide-binding: (2e-21) regulatory protein, Crp: (5.9e-05); KEGG: tth:TTC1072 transcription regulator, crp family, ev=3e-21, 33% identity YP_604438.1 KEGG: dra:DR1694 hypothetical protein, ev=1e-176, 79% identity YP_604439.1 PFAM: NAD-dependent epimerase/dehydratase: (0.0018) short-chain dehydrogenase/reductase SDR: (3.4e-10); KEGG: tth:TTC0410 short chain dehydrogenase, ev=4e-31, 40% identity YP_604441.1 PFAM: Endonuclease/exonuclease/phosphatase: (1.4e-27); SMART: PKD: (0.0073); KEGG: dra:DRB0067 extracellular nuclease, , ev=0.0, 55% identity YP_604442.1 KEGG: dra:DR0410 inorganic pyrophosphatase-related protein, ev=8e-27, 54% identity YP_604443.1 PFAM: short-chain dehydrogenase/reductase SDR: (2.6e-28); KEGG: dra:DR0411 short chain dehydrogenase, ev=1e-98, 80% identity YP_604444.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (1.7e-18); KEGG: dra:DR0412 pyridine nucleotide-disulphide oxidoreductase, class II, ev=1e-121, 70% identity YP_604445.1 TIGRFAM: ATP-dependent helicase HrpB: (0); PFAM: helicase-like: (4.4e-11) helicase-associated region: (1.3e-12) DEAD/DEAH box helicase-like: (2.7e-05) Helicase ATP-dependent-like: (1.2e-87); KEGG: dra:DR0420 ATP-dependent helicase, ev=0.0, 76% identity YP_604446.1 PFAM: Rad52/22 double-strand break repair protein: (1e-53); KEGG: dra:DR0423 hypothetical protein, ev=9e-92, 85% identity YP_604447.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin: (5.4e-85) peptidase-like: (0.00044) proteinase inhibitor I9, subtilisin propeptide: (3.4e-14); KEGG: dra:DR2322 serine protease, subtilase family, C-terminal fragment, ev=1e-115, 75% identity YP_604448.1 PFAM: imidazoleglycerol-phosphate dehydratase: (1.1e-62); KEGG: dra:DR0424 imidazoleglycerol-phosphate dehydratase, ev=1e-89, 84% identity YP_604449.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_604450.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_604451.1 KEGG: dra:DR1847 hypothetical protein, ev=1e-15, 58% identity YP_604452.1 KEGG: dra:DR1791 anthranilate synthase component I, ev=0.0, 80% identity; TIGRFAM: anthranilate synthase component I: (3.6e-216); PFAM: Anthranilate synthase component I and chorismate binding protein: (2.6e-173) Anthranilate synthase component I-like: (1.1e-43) YP_604453.1 PFAM: S23 ribosomal: (1.7e-28); KEGG: bmb:BruAb2_0463 hypothetical protein, ev=1e-18, 42% identity YP_604454.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_604455.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_604456.1 PFAM: regulatory proteins, AsnC/Lrp: (3.9e-15); KEGG: dra:DR0200 transcriptional regulator, Lrp/AsnC family, ev=3e-66, 80% identity YP_604457.1 TIGRFAM: Protein of unknown function DUF160: (3e-114); PFAM: Radical SAM: (5.1e-17); KEGG: dra:DRA0027 lysine 2,3-aminomutase, ev=0.0, 88% identity YP_604458.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_604459.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen: (1.6e-13) Redoxin: (7.8e-19); KEGG: dra:DR1209 bacterioferritin comigratory protein, ev=1e-59, 74% identity YP_604460.1 TIGRFAM: tRNA(Ile)-lysidine synthetase-like: (2.8e-58); PFAM: CMP/dCMP deaminase, zinc-binding: (1.3e-34) PP-loop: (2.7e-74); KEGG: dra:DR1207 cell cycle protein MesJ, /cytosine deaminase-related protein, ev=0.0, 68% identity YP_604461.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_604462.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_604463.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_604464.1 KEGG: dra:DR1474 hypothetical protein, ev=1e-79, 65% identity YP_604465.1 PFAM: PspA/IM30: (2.9e-83); KEGG: dra:DR1473 phage shock protein A, ev=1e-97, 84% identity YP_604466.1 KEGG: dra:DR1699 hypothetical protein, ev=5e-74, 60% identity YP_604467.1 PFAM: PilT protein-like: (4.7e-13); SMART: Nucleotide binding protein, PINc: (9e-13); KEGG: dra:DR1118 hypothetical protein, ev=1e-130, 67% identity YP_604468.1 PFAM: Saccharopine dehydrogenase: (3.4e-175); KEGG: dra:DR1252 hypothetical protein, ev=0.0, 80% identity YP_604469.1 KEGG: dra:DR1254 hypothetical protein, ev=4e-12, 48% identity YP_604470.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_604471.1 PFAM: NHL repeat: (0.022); KEGG: dra:DR1257 L-sorbosone dehydrogenase, ev=1e-164, 75% identity YP_604472.1 PFAM: nitroreductase: (3.4e-20); KEGG: dra:DR1399 oxidoreductase, , ev=9e-97, 66% identity YP_604473.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes: (1.3e-135) aromatic amino acid beta-eliminating lyase/threonine aldolase: (0.0004); KEGG: tte:TTE1574 cystathionine gamma-synthase, ev=6e-83, 44% identity YP_604474.1 PFAM: protein of unknown function DUF99: (9.8e-31); KEGG: dra:DRA0167 conserved hypothetical protein, ev=2e-66, 71% identity YP_604475.1 PFAM: Cold-shock protein, DNA-binding: (3.2e-36); SMART: Cold shock protein: (2e-31); KEGG: dra:DR0907 cold shock protein, CSD family, ev=2e-30, 71% identity YP_604476.1 PFAM: NUDIX hydrolase: (6.5e-28); KEGG: ttj:TTHA1880 MutT/NUDIX family protein, ev=8e-26, 52% identity YP_604477.1 KEGG: dra:DR2089 ferripyochelin-binding protein, ev=1e-62, 70% identity YP_604478.1 KEGG: dra:DR2090 hypothetical protein, ev=1e-101, 67% identity YP_604479.1 KEGG: dra:DR2164 lytB protein, ev=1e-152, 82% identity; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase: (1.5e-143); PFAM: LytB protein: (1.8e-106) YP_604480.1 KEGG: dra:DR1179 hypothetical protein, ev=1e-143, 56% identity YP_604481.1 KEGG: dra:DR0790 hypothetical protein, ev=0.0, 77% identity YP_604482.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (8.7e-08); KEGG: tth:TTC0096 thioredoxin reductase, ev=4e-57, 40% identity YP_604483.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (0.00039); KEGG: dra:DR0496 ferredoxin/ferredoxin--NADP reductase, , ev=0.0, 76% identity YP_604484.1 PFAM: cyclic nucleotide-binding: (9.6e-14) regulatory protein, Crp: (9.1e-05); KEGG: dra:DR0997 transcriptional regulator, FNR/CRP family, ev=1e-90, 93% identity YP_604485.1 TIGRFAM: DNA gyrase, A subunit: (0); PFAM: DNA gyrase/topoisomerase IV, subunit A: (1.5e-261) DNA gyrase C-terminal repeat, beta-propeller: (1.3e-17); KEGG: dra:DR1913 DNA gyrase, subunit A, ev=0.0, 87% identity YP_604487.1 PFAM: Roadblock/LC7: (1.8e-10); KEGG: dra:DR0995 hypothetical protein, ev=2e-40, 75% identity YP_604488.1 KEGG: dra:DR0994 hypothetical protein, ev=6e-30, 61% identity YP_604489.1 KEGG: dra:DR0993 hypothetical protein, ev=1e-20, 53% identity YP_604490.1 PFAM: LmbE-like protein: (2e-49); KEGG: dra:DR0450 hypothetical protein, ev=1e-118, 77% identity YP_604491.1 KEGG: dra:DR0734 hypothetical protein, ev=3e-21, 72% identity YP_604492.1 PFAM: glutamyl-tRNA synthetase, class Ic: (4e-34); KEGG: dra:DR1687 glutamyl-tRNA synthetase-related protein, ev=1e-121, 74% identity YP_604493.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_604494.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_604495.1 PFAM: protein of unknown function DUF892: (2.6e-60); KEGG: atc:AGR_L_1433 YciF protein, ev=1e-36, 48% identity YP_604496.1 KEGG: dra:DR1322 conserved hypothetical protein, ev=2e-52, 69% identity YP_604497.1 PFAM: beta-lactamase-like: (5.5e-14); KEGG: dra:DR1823 hypothetical protein, ev=1e-113, 78% identity YP_604498.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_604499.1 KEGG: dra:DR1781 hypothetical protein, ev=3e-83, 42% identity YP_604500.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_604501.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_604502.1 PFAM: cell wall hydrolase/autolysin: (1.2e-68); KEGG: dra:DR1632 N-acetylmuramoyl-L-alanine amidase, , ev=0.0, 58% identity YP_604504.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_604505.1 KEGG: dra:DR0045 hypothetical protein, ev=7e-53, 59% identity YP_604506.1 KEGG: dra:DR2569 hypothetical protein, ev=2e-69, 56% identity YP_604507.1 PFAM: acyltransferase 3: (5.5e-06); KEGG: dra:DR2012 hypothetical protein, ev=1e-109, 59% identity YP_604508.1 PFAM: amino acid-binding ACT: (9.4e-08) Prephenate dehydrogenase: (4.2e-81); KEGG: dra:DR1122 prephenate dehydrogenase, ev=1e-166, 83% identity YP_604509.1 PFAM: glycosyl transferase, family 2: (1.1e-20); KEGG: dra:DR1080 RfbJ protein/conserved hypothetical protein, ev=8e-84, 76% identity YP_604510.1 PFAM: transposase, IS4: (6.3e-22); KEGG: dra:DRC0033 transposase, , ev=1e-94, 63% identity YP_604511.1 PFAM: peptidase M50: (2.4e-64); KEGG: dra:DR1507 hypothetical zinc metalloprotease, ev=1e-146, 70% identity YP_604512.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_604513.1 PFAM: phosphatidate cytidylyltransferase: (8.5e-84); KEGG: dra:DR1509 phosphatidate cytidylyltransferase, ev=1e-125, 80% identity YP_604514.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_604515.1 Catalyzes the phosphorylation of UMP to UDP YP_604516.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_604517.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_604519.1 KEGG: dra:DR0454 undecaprenyl-diphosphatase, ev=1e-120, 76% identity; TIGRFAM: undecaprenol kinase, : (2.8e-71); PFAM: Bacitracin resistance protein BacA: (3e-123) YP_604522.1 KEGG: gvi:gll2346 hypothetical protein, ev=5e-09, 30% identity YP_604523.1 PFAM: guanine-specific ribonuclease N1 and T1: (7.4e-14); KEGG: dra:DR0453 guanyl-specific ribonuclease SA, ev=2e-35, 51% identity YP_604524.1 KEGG: dra:DR0452 hypothetical protein, ev=2e-46, 65% identity YP_604525.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_604526.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_604527.1 PFAM: ABC transporter related: (2.4e-57) TOBE: (6.6e-15) Transport-associated OB: (9.6e-13); SMART: ATPase: (1.1e-16); KEGG: dra:DR2153 polar amino acid transport system ATP-binding protein, ev=0.0, 82% identity YP_604528.1 PFAM: extracellular solute-binding protein, family 3: (8.8e-84); KEGG: dra:DR2154 polar amino acid transport system substrate-binding protein, ev=1e-116, 81% identity YP_604529.1 TIGRFAM: Amino acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine: (1.1e-33); PFAM: binding-protein-dependent transport systems inner membrane component: (8.3e-29); KEGG: dra:DR2155 polar amino acid transport system permease, ev=1e-109, 80% identity YP_604530.1 TIGRFAM: TRAP transporter 4TM/12TM fusion protein: (5.5e-196); PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit: (9.5e-75); KEGG: dra:DR1653 hypothetical protein, ev=0.0, 77% identity YP_604531.1 TIGRFAM: TRAP transporter solute receptor, TAXI family: (1.6e-104); KEGG: dra:DR1649 immunogenic protein, ev=1e-132, 76% identity YP_604532.1 PFAM: SMC protein-like: (0.00011) ABC transporter related: (5.4e-69); SMART: ATPase: (1.3e-20); KEGG: dra:DR1648 amino acid ABC transporter ATP-binding protein, ev=1e-111, 82% identity YP_604533.1 PFAM: major facilitator superfamily MFS_1: (2e-07); KEGG: ttj:TTHA0314 hypothetical protein, ev=1e-66, 40% identity YP_604534.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family: (1.8e-37); PFAM: glycosyl transferase WecB/TagA/CpsF: (1.2e-73); KEGG: dra:DR1645 UDP-N-acetyl-D-mannosaminuronic acid transferase, ev=1e-110, 79% identity YP_604535.1 KEGG: dra:DR1417 penicillin-binding protein 1B McrB, , ev=1e-46, 74% identity YP_604536.1 PFAM: glycosyl transferase, family 51: (6.1e-58) penicillin-binding protein, transpeptidase: (8.9e-27); KEGG: dra:DR1417 penicillin-binding protein 1B McrB, , ev=0.0, 69% identity YP_604537.1 PFAM: response regulator receiver: (3e-30); KEGG: dra:DR1418 response regulator, ev=2e-54, 83% identity YP_604538.1 PFAM: AMP-dependent synthetase and ligase: (5.6e-144); KEGG: dra:DR1692 long-chain fatty acid--CoA ligase, ev=0.0, 70% identity YP_604539.1 PFAM: CMP/dCMP deaminase, zinc-binding: (7.5e-18); KEGG: dra:DR0603 cytidine/deoxycytidylate deaminase/NUDIX/methyltransferase domains protein, ev=7e-16, 35% identity YP_604540.1 PFAM: PfkB: (1e-60); KEGG: dra:DRA0055 ribokinase, ev=6e-69, 50% identity YP_604541.1 KEGG: dra:DR1194 hypothetical protein, ev=4e-51, 62% identity YP_604542.1 KEGG: dra:DR1479 hypothetical protein, ev=3e-24, 77% identity YP_604543.1 PFAM: protein of unknown function DUF503: (1.1e-45); KEGG: dra:DR1478 hypothetical protein, ev=1e-42, 80% identity YP_604544.1 TIGRFAM: Peptidase S26A, signal peptidase I: (3e-37); PFAM: peptidase S24, S26A and S26B: (4.1e-09); KEGG: dra:DR1427 signal peptidase I, ev=1e-106, 70% identity YP_604545.1 PFAM: Patatin: (3e-41); KEGG: tth:TTC1004 serine protease, ev=8e-50, 45% identity YP_604546.1 PFAM: protein kinase: (1.5e-12); SMART: Tyrosine protein kinase: (2.8e-09) Serine/threonine protein kinase: (8.7e-16); KEGG: dra:DR1851 serine/threonine-protein kinase-related protein, ev=3e-77, 61% identity YP_604547.1 PFAM: glycoside hydrolase, family 3-like: (4.6e-42); KEGG: dra:DR1333 glycosyl hyrolase, family 3, ev=1e-136, 75% identity YP_604548.1 PFAM: DegV: (6.5e-60); KEGG: dra:DR0500 hypothetical protein, ev=1e-104, 67% identity YP_604549.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent: (0.0017) 6-phosphogluconate dehydrogenase, NAD-binding: (1.2e-49); KEGG: dra:DR0499 3-hydroxyisobutyrate dehydrogenase, ev=1e-104, 68% identity YP_604550.1 PFAM: Auxin Efflux Carrier: (1.6e-14); KEGG: ttj:TTHA0659 hypothetical protein, ev=2e-45, 41% identity YP_604551.1 PFAM: tRNA/rRNA methyltransferase (SpoU): (2.1e-45); KEGG: dra:DR1017 rRNA methylase, ev=4e-98, 71% identity YP_604552.1 TIGRFAM: oligoendopeptidase F: (1.6e-260); PFAM: peptidase M3A and M3B, thimet/oligopeptidase F: (4.6e-124) Oligopeptidase F: (2.5e-18); KEGG: dra:DR1627 oligoendopeptidase, ev=0.0, 76% identity YP_604553.1 KEGG: dra:DR1245 hypothetical protein, ev=1e-75, 90% identity YP_604554.1 PFAM: Peptidoglycan-binding LysM: (1.1e-17) Rare lipoprotein A: (5.5e-22); KEGG: hdu:HD2017 possible rare lipoprotein A, ev=2e-16, 41% identity YP_604555.1 PFAM: peptidase M24: (1.1e-78); KEGG: dra:DR1246 proline dipeptidase, ev=1e-134, 70% identity YP_604556.1 catalyzes the interconversion of succinyl-CoA and succinate YP_604557.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit: (3.5e-116); PFAM: CoA-binding: (1.3e-46) ATP-citrate lyase/succinyl-CoA ligase: (4.7e-37); KEGG: dra:DR1248 succinyl-CoA synthetase alpha chain, ev=1e-137, 82% identity YP_604558.1 PFAM: transposase, IS4: (0.0015); KEGG: gka:GK3310 transposase, ev=3e-07, 29% identity YP_604559.1 KEGG: dra:DR1048 hypothetical protein, ev=7e-12, 56% identity YP_604563.1 KEGG: dra:DRC0017 transposase, ev=1e-140, 72% identity YP_604564.1 PFAM: phage integrase: (0.04); KEGG: dra:DRC0018 integrase/recombinase XerD, , ev=4e-52, 82% identity YP_604565.1 KEGG: dra:DR1249 hypothetical protein, ev=4e-41, 47% identity YP_604566.1 PFAM: glycosyl transferase, group 1: (7.8e-45); KEGG: dra:DR1555 hypothetical protein, ev=1e-170, 79% identity YP_604567.1 TIGRFAM: degV family protein: (5e-68); PFAM: DegV: (8.1e-40); KEGG: ttj:TTHA0951 DegV family protein, ev=4e-42, 37% identity YP_604568.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_604569.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_604570.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_604571.1 PFAM: Peptidoglycan-binding LysM: (3.8e-07) peptidase M23B: (3.9e-37); KEGG: tth:TTC0351 cell wall endopeptidase, family M23/M37, ev=7e-57, 36% identity YP_604572.1 PFAM: response regulator receiver: (1.8e-17); KEGG: tel:tll2364 two-component response regulator, ev=2e-13, 40% identity YP_604573.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_604574.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_604575.1 PFAM: alpha/beta hydrolase fold: (3.6e-23); KEGG: dra:DR1352 dihydrolipoamide acetyltransferase-related protein, ev=1e-80, 63% identity YP_604576.1 PFAM: alpha/beta hydrolase fold: (2.3e-13); KEGG: dra:DR1351 hydrolase, alpha/beta hydrolase fold family, ev=9e-88, 65% identity YP_604577.1 PFAM: oxidoreductase-like: (5.8e-21); KEGG: dra:DR1362 streptomycin biosynthesis protein StrI-related protein, ev=1e-177, 76% identity YP_604578.1 PFAM: NLP/P60: (5.3e-21); KEGG: dra:DR1361 endopeptidase-related protein, ev=1e-90, 62% identity YP_604579.1 PFAM: peptidase M19, renal dipeptidase: (7.7e-39); KEGG: ttj:TTHA1547 peptidase, ev=4e-63, 45% identity YP_604580.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (1.6e-11) HAD-superfamily hydrolase, subfamily IA, variant 1: (8.8e-05); PFAM: Haloacid dehalogenase-like hydrolase: (7.3e-27); KEGG: dra:DR1344 hydrolase, ev=6e-75, 64% identity YP_604581.1 PFAM: aminotransferase, class V: (2.4e-14); KEGG: dra:DR1350 aminotransferase, ev=1e-170, 78% identity YP_604582.1 PFAM: metallophosphoesterase: (1.1e-10); KEGG: dra:DR1360 hypothetical protein, ev=1e-108, 79% identity YP_604583.1 TIGRFAM: apolipoprotein N-acyltransferase: (1.1e-85); PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase: (0.00022); KEGG: dra:DR1353 acid tolerance protein Act206-related protein, ev=1e-159, 60% identity YP_604584.1 PFAM: phage integrase: (8.4e-17) phage integrase-like SAM-like: (0.00068); KEGG: pac:PPA1388 site-specific recombinase, ev=6e-26, 33% identity YP_604585.1 PFAM: diacylglycerol kinase, catalytic region: (4.4e-19); KEGG: dra:DR1363 hypothetical protein, ev=1e-131, 75% identity YP_604586.1 PFAM: cell surface receptor IPT/TIG: (8.7e-05); KEGG: dra:DR1364 hypothetical protein, ev=4e-39, 67% identity YP_604587.1 PFAM: aldehyde dehydrogenase: (3.5e-170); KEGG: dra:DRA0343 succinic-semialdehyde dehydrogenase, , ev=0.0, 70% identity YP_604588.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_604589.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_604590.1 PFAM: Phosphoglycerate mutase: (1.3e-08); KEGG: dra:DR1097 phosphoglycerate mutase, ev=7e-11, 40% identity YP_604591.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_604592.1 PFAM: phosphoesterase, PA-phosphatase related: (6e-32); KEGG: dra:DR1355 phosphatidylglycerophosphatase B-related protein, ev=3e-76, 63% identity YP_604593.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP YP_604594.1 KEGG: dra:DRA0298 copper resistance protein D, ev=1e-15, 49% identity YP_604595.1 KEGG: dra:DRA0298 copper resistance protein D, ev=6e-21, 44% identity YP_604596.1 PFAM: copper resistance protein CopC: (7.8e-32); KEGG: dra:DRA0299 copper resistance protein, , ev=3e-27, 52% identity YP_604597.1 PFAM: nuclear export factor GLE1: (5.3e-06); KEGG: bat:BAS1775 hypothetical protein, ev=9e-20, 37% identity YP_604599.1 KEGG: dra:DR1343 glyceraldehyde 3-phosphate dehydrogenase, ev=1e-158, 83% identity; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I: (1.8e-183); PFAM: glyceraldehyde 3-phosphate dehydrogenase: (1.3e-98) YP_604600.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_604601.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_604602.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_604603.1 PFAM: Phenazine biosynthesis PhzC/PhzF protein: (7.8e-96); KEGG: dra:DR1330 antibiotic biosynthesis protein, , ev=1e-110, 70% identity YP_604604.1 TIGRFAM: Cof protein: (9.3e-66) HAD-superfamily hydrolase subfamily IIB: (1.6e-09); PFAM: Haloacid dehalogenase-like hydrolase: (6.3e-08) sucrose-6F-phosphate phosphohydrolase: (8.1e-05) Haloacid dehalogenase-like hydrolase, type 3: (1.5e-30); KEGG: dra:DR1329 hypothetical protein, ev=1e-100, 69% identity YP_604605.1 catalyzes branch migration in Holliday junction intermediates YP_604606.1 PFAM: NAD-dependent epimerase/dehydratase: (0.0019) short-chain dehydrogenase/reductase SDR: (1.5e-11); KEGG: dra:DR1700 daunorubicin C-13 ketoreductase, ev=5e-90, 61% identity YP_604607.1 PFAM: gamma-glutamyltranspeptidase: (7.6e-212); KEGG: dra:DR1524 gamma-glutamyltranspeptidase, ev=0.0, 81% identity YP_604608.1 PFAM: PfkB: (2.1e-52); KEGG: dra:DR1525 carbohydrate kinase, PfkB family, ev=1e-133, 78% identity YP_604609.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_604610.1 PFAM: TPR repeat: (0.0049) Tetratricopeptide TPR_2: (5.9e-05); SMART: Tetratricopeptide region: (0.22); KEGG: dra:DR1528 hypothetical protein, ev=3e-36, 59% identity YP_604611.1 PFAM: protein of unknown function UPF0031: (2.6e-40) YjeF-related protein-like: (1.7e-44); KEGG: dra:DR1529 hypothetical protein, ev=1e-175, 68% identity YP_604612.1 KEGG: dra:DR1230 hypothetical protein, ev=1e-47, 47% identity YP_604613.1 TIGRFAM: Drug resistance transporter EmrB/QacA subfamily: (6e-35); PFAM: major facilitator superfamily MFS_1: (1.1e-54); KEGG: dra:DRA0061 drug transport protein, , ev=0.0, 52% identity YP_604614.1 PFAM: regulatory protein, MarR: (5.6e-15); KEGG: nfa:nfa53480 transcriptional regulator, ev=2e-07, 38% identity YP_604615.1 PFAM: Pyrrolo-quinoline quinone: (1.4e-06) cytochrome c, class I: (0.0084); KEGG: bja:blr6207 probable quinoprotein ethanol dehydrogenase precursor, ev=8e-85, 37% identity YP_604617.1 TIGRFAM: S6 modification enzyme RimK: (4.5e-160) Lysine biosynthesis enzyme LysX: (9.9e-188); PFAM: protein of unknown function DUF201: (0.00011) RimK-like ATP-grasp: (7e-59); KEGG: dra:DR2194 ribosomal protein S6 modification protein, ev=1e-143, 86% identity YP_604618.1 TIGRFAM: lysine biosynthesis protein LysW: (2.9e-33); KEGG: ttj:TTHA1908 lysine biosynthesis protein LysW, ev=6e-11, 65% identity YP_604619.1 PFAM: zinc finger, DHP-type: (0.015); KEGG: dra:DR2193 hypothetical protein, ev=1e-25, 63% identity YP_604620.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_604622.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_604623.1 PFAM: TrkA-C: (3.2e-10); KEGG: dra:DR1148 TrkA domain protein, ev=3e-59, 68% identity YP_604624.1 PFAM: sodium/hydrogen exchanger: (6.1e-67); KEGG: dra:DR1149 Na+/H+ antiporter, , ev=1e-161, 77% identity YP_604625.1 PFAM: Radical SAM: (7.2e-20); SMART: Elongator protein 3/MiaB/NifB: (9.3e-33); KEGG: dra:DR1298 hypothetical protein, ev=0.0, 90% identity YP_604626.1 PFAM: GCN5-related N-acetyltransferase: (8.8e-10); KEGG: atc:AGR_C_2411 acetyltransferase, ev=5e-44, 48% identity YP_604627.1 KEGG: dra:DR1464 hypothetical protein, ev=8e-15, 57% identity YP_604628.1 KEGG: tth:TTC0619 probable L-aspartate oxidase, ev=1e-125, 53% identity; TIGRFAM: L-aspartate oxidase: (6.1e-154); PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like: (9.5e-113) FAD dependent oxidoreductase: (0.00072) FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (0.00013) YP_604629.1 KEGG: tth:TTC0621 nicotinate-nucleotide pyrophosphorylase [carboxylating], ev=1e-72, 58% identity; TIGRFAM: nicotinate-nucleotide pyrophosphorylase: (2.2e-120); PFAM: Quinolinate phosphoribosyl transferase: (7.7e-72) YP_604630.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_604632.1 PFAM: isocitrate/isopropylmalate dehydrogenase: (1.9e-155); KEGG: dra:DR1540 isocitrate dehydrogenase, ev=0.0, 85% identity YP_604633.1 KEGG: dra:DR1539 hypothetical protein, ev=3e-18, 55% identity YP_604634.1 PFAM: binding-protein-dependent transport systems inner membrane component: (3.2e-11); KEGG: cvi:CV2898 probable sugar ABC transporter permease, ev=9e-84, 53% identity YP_604635.1 PFAM: binding-protein-dependent transport systems inner membrane component: (3.5e-13); KEGG: cvi:CV0260 probable ABC transporter sugar permease, ev=5e-63, 45% identity YP_604636.1 KEGG: bcl:ABC3582 hypothetical protein, ev=2e-59, 35% identity YP_604637.1 KEGG: dra:DR1064 hypothetical protein, ev=6e-50, 69% identity YP_604638.1 KEGG: tte:TTE2409 hypothetical protein, ev=9e-57, 30% identity YP_604639.1 PFAM: ROK: (3e-27); KEGG: stt:t3253 N-acetylmannosamine kinase, ev=6e-42, 40% identity YP_604640.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_604641.1 KEGG: dra:DR1641 hypothetical protein, ev=8e-75, 79% identity YP_604642.1 KEGG: dra:DR1644 hypothetical protein, ev=2e-54, 55% identity YP_604643.1 PFAM: aminotransferase class-III: (1.6e-89); KEGG: dra:DRA0121 aminotransferase, class III, ev=1e-179, 74% identity YP_604644.1 KEGG: nfa:nfa32370 hypothetical protein, ev=1e-39, 59% identity YP_604645.1 PFAM: acyl-CoA dehydrogenase-like: (6.5e-70) Acyl-CoA dehydrogenase, type 2-like: (1.8e-37); KEGG: dra:DR1255 acyl-CoA dehydrogenase, ev=1e-179, 81% identity YP_604646.1 KEGG: dra:DR1256 hypothetical protein, ev=2e-25, 74% identity YP_604648.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_604649.1 PFAM: permease YjgP/YjgQ: (1.3e-63); KEGG: dra:DR1075 hypothetical protein, ev=1e-170, 80% identity YP_604650.1 PFAM: glycosyltransferase 28-like: (2.7e-05) Monogalactosyldiacylglycerol synthase: (3.2e-28); KEGG: dra:DR1076 cell wall synthesis protein, , ev=1e-114, 58% identity YP_604651.1 PFAM: polysaccharide deacetylase: (1.6e-37); KEGG: dra:DR1077 chitooligosaccharide deacetylase, ev=1e-150, 69% identity YP_604652.1 PFAM: Methyltransferase type 11: (6.2e-23) Methyltransferase type 12: (1e-22); KEGG: dra:DR1078 antibiotic biosynthesis protein LmbJ, , ev=1e-105, 67% identity YP_604653.1 KEGG: dra:DR1889 hypothetical protein, ev=7e-55, 58% identity YP_604654.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin: (7.2e-46); KEGG: dra:DR1536 serine protease, subtilase family, ev=0.0, 55% identity YP_604655.1 PFAM: extracellular solute-binding protein, family 5: (1.1e-96); KEGG: dra:DR1290 extracellular solute-binding protein, family 5, ev=0.0, 77% identity YP_604656.1 PFAM: binding-protein-dependent transport systems inner membrane component: (7.8e-61); KEGG: dra:DR0959 peptide ABC transporter permease, ev=1e-143, 73% identity YP_604657.1 PFAM: binding-protein-dependent transport systems inner membrane component: (7.5e-51); KEGG: dra:DR0958 peptide ABC transporter permease, ev=1e-158, 84% identity YP_604659.1 KEGG: dra:DR1480 AlgP-related protein, ev=5e-52, 39% identity YP_604660.1 TIGRFAM: DNA repair protein RecN: (1.8e-148); PFAM: SMC protein-like: (7.7e-11); KEGG: dra:DR1477 DNA repair protein, ev=0.0, 71% identity YP_604661.1 KEGG: dra:DR1623 hypothetical protein, ev=2e-93, 52% identity YP_604662.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_604663.1 PFAM: protein of unknown function DUF6, transmembrane: (3.4e-16); KEGG: dra:DR1295 PecM-related protein, ev=1e-110, 73% identity YP_604664.1 KEGG: dra:DR2195 alpha-glucan phosphorylase, , ev=0.0, 77% identity; TIGRFAM: Alpha-glucan phosphorylase: (0); PFAM: glycosyl transferase, family 35: (0.00028) YP_604666.1 PFAM: protein of unknown function DUF1622: (1.5e-28); KEGG: dra:DR1328 hypothetical protein, ev=3e-24, 56% identity YP_604667.1 PFAM: phosphoesterase, DHHA1: (1.2e-05) Threonyl/alanyl tRNA synthetase, SAD: (2.6e-08); KEGG: dra:DR0502 alanyl-tRNA synthetase-related protein, ev=1e-129, 63% identity YP_604668.1 PFAM: aminoglycoside 3-N-acetyltransferase: (1.2e-11); KEGG: dra:DR2034 aminoglycoside N3'-acetyltransferase, type IV, ev=1e-106, 76% identity YP_604669.1 PFAM: glutamine synthetase, catalytic region: (1.2e-16); KEGG: dra:DR2033 glutamine synthase, ev=0.0, 77% identity YP_604670.1 KEGG: dra:DR0451 glutamine synthase, ev=0.0, 80% identity; TIGRFAM: glutamine synthetase, type I: (4.1e-212); PFAM: glutamine synthetase, catalytic region: (4.7e-146) glutamine synthetase, beta-Grasp: (3.9e-07) YP_604671.1 PFAM: Extracellular ligand-binding receptor: (4.4e-47); KEGG: dra:DR1038 branched-chain amino acid transport system substrate-binding protein, ev=1e-134, 63% identity YP_604672.1 PFAM: inner-membrane translocator: (1.3e-30); KEGG: dra:DR1037 branched-chain amino acid transport system permease, ev=1e-110, 64% identity YP_604673.1 PFAM: inner-membrane translocator: (1.4e-26); KEGG: dra:DR1036 branched-chain amino acid transport system permease, ev=9e-97, 60% identity YP_604674.1 PFAM: ABC transporter related: (4.3e-49); SMART: ATPase: (5.7e-12); KEGG: dra:DR1035 branched-chain amino acid transport system ATP-binding protein, ev=1e-120, 80% identity YP_604675.1 PFAM: ABC transporter related: (2.6e-55); SMART: ATPase: (2.8e-14); KEGG: dra:DR1034 branched-chain amino acid transport system ATP-binding protein, ev=1e-104, 79% identity YP_604676.1 PFAM: AAA ATPase, central region: (6.3e-11) Clp, N terminal: (0.015) ATPase associated with various cellular activities, AAA_5: (1.4e-06) ATPase AAA-2: (3.3e-116); SMART: ATPase: (6.6e-17); KEGG: dra:DR1046 ATP-dependent Clp protease, ATP-binding subunit ClpB, ev=0.0, 82% identity YP_604677.1 KEGG: dra:DR1067 hypothetical protein, ev=6e-10, 59% identity YP_604678.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_604679.1 KEGG: dra:DR1104 hypothetical protein, ev=4e-28, 64% identity YP_604680.1 KEGG: vvy:VV1808 hypothetical protein, ev=2e-25, 61% identity YP_604681.1 PFAM: AAA ATPase, central region: (4.6e-06) Clp, N terminal: (3e-10) ATPase associated with various cellular activities, AAA_5: (2.2e-05) ATPase AAA-2: (3.5e-90); SMART: ATPase: (2.1e-17); KEGG: dra:DR1117 ATP-dependent Clp protease, ATP-binding subunit ClpC, ev=0.0, 89% identity YP_604682.1 PFAM: PDZ/DHR/GLGF: (0.0098) peptidase S41: (9e-32); KEGG: dra:DR1491 carboxyl-terminal protease, , ev=1e-110, 50% identity YP_604683.1 PFAM: fumarylacetoacetate (FAA) hydrolase: (2.3e-67); KEGG: dra:DR1609 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase-related protein, ev=1e-115, 80% identity YP_604684.1 PFAM: NUDIX hydrolase: (6e-27); KEGG: sth:STH2366 mutator MutT protein, ev=8e-56, 55% identity YP_604685.1 PFAM: aminotransferase class-III: (1.4e-78); KEGG: dra:DR1415 ornithine aminotransferase, ev=0.0, 77% identity YP_604686.1 KEGG: dra:DR1416 hypothetical protein, ev=2e-47, 57% identity YP_604687.1 PFAM: acyl-CoA dehydrogenase-like: (1.1e-37) Acyl-CoA dehydrogenase, type 2-like: (6.6e-05); KEGG: dra:DR0551 glutaryl-CoA dehydrogenase, , ev=1e-173, 73% identity YP_604688.1 KEGG: dra:DR1483 hypothetical protein, ev=1e-104, 65% identity YP_604689.1 PFAM: major facilitator superfamily MFS_1: (8e-57); KEGG: dra:DR1327 multidrug-efflux transporter ev=0.0, 73% identity YP_604690.1 PFAM: NAD-dependent epimerase/dehydratase: (9.7e-06); KEGG: bps:BPSL1273 hypothetical protein, ev=4e-46, 50% identity YP_604691.1 PFAM: protein of unknown function UPF0074: (1.4e-36); KEGG: bld:BLi03912 YwnA, ev=2e-26, 42% identity YP_604692.1 PFAM: helicase-like: (4.9e-10) HRDC: (5e-23); KEGG: dra:DR1289 DNA helicase RecQ, ev=1e-31, 76% identity YP_604693.1 KEGG: dra:DR1490 hypothetical protein, ev=3e-25, 38% identity YP_604694.1 PFAM: Alcohol dehydrogenase, zinc-binding: (2.8e-16) Alcohol dehydrogenase GroES-like: (3.8e-16); KEGG: rpa:RPA4658 zinc-binding dehydrogenase (related to alcohol dehydrogenase, NADPH quinone oxidoreductase), ev=4e-96, 56% identity YP_604696.1 PFAM: acyl-CoA dehydrogenase-like: (2.4e-13) Acyl-CoA dehydrogenase, type 2-like: (1.2e-20); KEGG: sth:STH2357 acyl-CoA dehydrogenase, short-chain specific, ev=4e-53, 40% identity YP_604697.1 TIGRFAM: cell envelope-related function transcriptional attenuator common domain: (1.9e-47); PFAM: cell envelope-related transcriptional attenuator: (1.1e-60); KEGG: dra:DR1488 membrane-bound protein LytR, ev=1e-132, 61% identity YP_604698.1 PFAM: protein of unknown function DUF150: (1.3e-41); KEGG: dra:DR1796 hypothetical protein, ev=1e-49, 64% identity YP_604699.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_604700.1 PFAM: protein of unknown function DUF448: (4.2e-21); KEGG: dra:DR1798 hypothetical protein, ev=1e-24, 68% identity YP_604701.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_604702.1 KEGG: mta:Moth_1011 hypothetical protein, ev=3e-15, 31% identity YP_604703.1 KEGG: dra:DR1821 hypothetical protein, ev=8e-13, 45% identity YP_604704.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_604705.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_604706.1 PFAM: cytochrome c biogenesis protein, transmembrane region: (1.1e-51); KEGG: dra:DR1300 cytochrome c-type biogenesis protein, , ev=1e-106, 87% identity YP_604707.1 PFAM: ABC transporter related: (1.8e-32); SMART: ATPase: (3.5e-12); KEGG: dra:DR0406 ABC transporter ATP-binding protein, ev=2e-46, 51% identity YP_604708.1 PFAM: cytochrome c-type biogenesis protein CcmB: (6.2e-17); KEGG: dra:DR0407 cytochrome c-type biogenesis protein, heme exporter protein B, ev=9e-46, 48% identity YP_604709.1 KEGG: dra:DR0691 hypothetical protein, ev=3e-33, 35% identity YP_604710.1 PFAM: cytochrome c assembly protein: (8.6e-28); KEGG: dra:DR0348 cytochrome c-type biogenesis protein, heme exporter protein C, ev=3e-69, 54% identity YP_604711.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_604712.1 PFAM: cytochrome c assembly protein: (9.7e-33); KEGG: dra:DR0346 cytochrome c-type biogenesis protein CcmF, ev=0.0, 57% identity YP_604713.1 PFAM: Redoxin: (9.6e-31) Thioredoxin domain: (0.006); KEGG: dra:DR0189 thiol:disulfide interchange protein, ev=5e-64, 65% identity YP_604714.1 PFAM: cytochrome C biogenesis protein: (1.4e-29); KEGG: dra:DR0344 cytochrome c-type biogenesis protein CcmH, ev=5e-22, 40% identity YP_604715.1 PFAM: TPR repeat: (0.0002) cytochrome c, class I: (0.021) Tetratricopeptide TPR_2: (2e-05); KEGG: dra:DR0343 cytochrome c family protein, ev=4e-54, 38% identity YP_604716.1 PFAM: Rieske [2Fe-2S] region: (4.2e-05); KEGG: dra:DR0342 cytochrome complex iron-sulfur subunit, , ev=4e-54, 55% identity YP_604717.1 PFAM: luciferase-like: (4.6e-24); KEGG: sth:STH550 oxidoreductase, ev=1e-143, 72% identity YP_604718.1 PFAM: HpcH/HpaI aldolase: (1.8e-77); KEGG: dra:DR1240 citrate lyase beta chain, ev=1e-119, 81% identity YP_604719.1 PFAM: MaoC-like dehydratase: (2.8e-29); KEGG: dra:DR1239 MaoC-related protein, ev=2e-63, 72% identity YP_604720.1 KEGG: rba:RB12019 probable oxidoreductase, ev=4e-37, 39% identity YP_604721.1 KEGG: bce:BC2853 D-threo-aldose 1-dehydrogenase, ev=9e-17, 50% identity YP_604722.1 TIGRFAM: Homocitrate synthase, fungi and archaea: (7.9e-185); PFAM: pyruvate carboxyltransferase: (1.9e-70); KEGG: dra:DR1238 homocitrate synthase, ev=0.0, 90% identity YP_604723.1 KEGG: dra:DR1178 hypothetical protein, ev=4e-70, 56% identity YP_604724.1 TIGRFAM: benzoate transporter: (3.3e-86); PFAM: Benzoate membrane transport protein: (4e-136) Xanthine/uracil/vitamin C permease: (0.014); KEGG: rru:Rru_A1144 benzoate membrane transport protein, ev=2e-78, 43% identity YP_604726.1 TIGRFAM: Cysteine desulphurase related: (6e-200); PFAM: aminotransferase, class V: (2.9e-52); KEGG: dra:DR0151 NifS-related protein, ev=1e-177, 78% identity YP_604728.1 PFAM: protein of unknown function DUF255: (7.8e-49); KEGG: dra:DR0844 hypothetical protein, ev=0.0, 72% identity YP_604729.1 PFAM: LmbE-like protein: (2.5e-38); KEGG: dra:DRA0063 hypothetical protein, ev=8e-86, 51% identity YP_604730.1 KEGG: dra:DR0845 ribose 5-phosphate isomerase A, ev=1e-95, 77% identity; TIGRFAM: ribose 5-phosphate isomerase: (1.1e-112); PFAM: Ribose 5-phosphate isomerase: (4.7e-85) YP_604731.1 KEGG: dra:DR1205 deoxyribose-phosphate aldolase, ev=2e-95, 80% identity; TIGRFAM: deoxyribose-phosphate aldolase: (2.4e-82); PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase: (1.5e-77) YP_604732.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_604733.1 PFAM: OsmC-like protein: (5.1e-24); KEGG: dra:DR1177 redox protein, ev=7e-60, 86% identity YP_604734.1 PFAM: response regulator receiver: (1e-06) ATP-binding region, ATPase-like: (4.6e-35) histidine kinase A-like: (4.5e-14); KEGG: dra:DR1175 sensor histidine kinase/response regulator, ev=1e-162, 78% identity YP_604735.1 PFAM: ATP-binding region, ATPase-like: (3.6e-36) histidine kinase A-like: (7.8e-18) PAS fold-3: (1.9e-19) PAS fold-4: (1.8e-09) PAS fold: (3.1e-12); SMART: PAS: (2.4e-11) PAC motif: (1.2e-08); KEGG: dra:DR1174 sensory box sensor histidine kinase, ev=0.0, 53% identity YP_604736.1 TIGRFAM: shikimate 5-dehydrogenase: (7.9e-64); PFAM: Shikimate/quinate 5-dehydrogenase: (3.4e-10) Shikimate dehydrogenase substrate binding-like: (1.5e-36); KEGG: dra:DR1173 shikimate 5-dehydrogenase, , ev=1e-86, 64% identity YP_604737.1 PFAM: PhoH-like protein: (2e-137) KH, type 1: (0.0042); KEGG: dra:DR1988 PhoH-related protein, ev=1e-163, 88% identity YP_604738.1 PFAM: protein of unknown function UPF0054: (4e-26); KEGG: dra:DR2092 hypothetical protein, ev=4e-73, 83% identity YP_604739.1 PFAM: diacylglycerol kinase: (3.5e-32); KEGG: dra:DR2093 diacylglycerol kinase, ev=3e-42, 73% identity YP_604740.1 PFAM: cyclic nucleotide-binding: (9e-18) regulatory protein, Crp: (8.9e-08); KEGG: dra:DR1646 nitrogen regulator, , ev=2e-89, 76% identity YP_604741.1 KEGG: dra:DR1647 hypothetical protein, ev=1e-123, 72% identity YP_604742.1 KEGG: nfa:nfa19010 hypothetical protein, ev=2e-23, 37% identity YP_604743.1 PFAM: peptidase U32: (3.4e-111); KEGG: dra:DR2130 protease, , ev=0.0, 77% identity YP_604744.1 PFAM: UspA: (8.4e-26); KEGG: dra:DR2132 hypothetical protein, ev=1e-31, 52% identity YP_604745.1 PFAM: Rhodanese-like: (7.3e-16); KEGG: ttj:TTHA0836 rhodanese-like domain protein, ev=1e-19, 41% identity YP_604746.1 PFAM: protein of unknown function DUF59: (3.4e-38); KEGG: dra:DR2165 hypothetical protein, ev=2e-50, 92% identity YP_604747.1 PFAM: peptidase, membrane zinc metallopeptidase, : (1e-135); KEGG: dra:DR0194 hypothetical protein, ev=1e-94, 76% identity YP_604748.1 PFAM: Stage V sporulation protein S: (1.8e-45); KEGG: ttj:TTHA0850 stage V sporulation protein S (SpoVS) related protein, ev=3e-28, 73% identity YP_604749.1 TIGRFAM: methionine aminopeptidase, type I: (9.4e-127); PFAM: peptidase M24: (2.5e-83); KEGG: dra:DR1311 methionine aminopeptidase, ev=1e-121, 80% identity YP_604750.1 PFAM: CBS: (6.4e-31) protein of unknown function DUF21: (8.6e-82) transporter-associated region: (1.4e-26); KEGG: dra:DR2176 similar to hemolysin, ev=0.0, 80% identity YP_604751.1 TIGRFAM: Cytidine deaminase, homotetrameric: (4e-70); PFAM: CMP/dCMP deaminase, zinc-binding: (1.8e-24); KEGG: dra:DR2177 cytidine deaminase, ev=1e-58, 75% identity YP_604752.1 TIGRFAM: isocitrate lyase: (6.6e-185); PFAM: isocitrate lyase and phosphorylmutase: (1.6e-236); KEGG: dra:DR0828 isocitrate lyase, ev=0.0, 89% identity YP_604753.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (9.9e-13); PFAM: Haloacid dehalogenase-like hydrolase: (9.6e-15); KEGG: dra:DR0827 hydrolase, CbbY/CbbZ/GpH/YieH family, ev=7e-93, 83% identity YP_604755.1 PFAM: phosphoesterase, RecJ-like: (2.2e-16) phosphoesterase, DHHA1: (3.4e-08); KEGG: dra:DR0826 hypothetical protein, ev=1e-139, 75% identity YP_604756.1 KEGG: dra:DR1985 beta-lactamase, , ev=1e-133, 60% identity YP_604757.1 TIGRFAM: degV family protein: (8.1e-117); PFAM: DegV: (8e-67); KEGG: dra:DR1986 DegV protein, ev=1e-102, 66% identity YP_604758.1 PFAM: diacylglycerol kinase, catalytic region: (1.4e-22); KEGG: dra:DR1560 hypothetical protein, ev=1e-104, 63% identity YP_604759.1 PFAM: UDP-N-acetylglucosamine 2-epimerase: (4e-100); KEGG: dra:DR1561 UDP-N-acetylglucosamine 2-epimerase, ev=1e-177, 84% identity YP_604760.1 PFAM: glycosyl transferase, family 4: (2.7e-34); KEGG: dra:DR1562 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase, ev=1e-156, 74% identity YP_604761.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_604762.1 PFAM: aminoglycoside phosphotransferase: (3.3e-18); KEGG: dra:DR1564 hypothetical protein, ev=1e-109, 73% identity YP_604763.1 PFAM: metal-dependent phosphohydrolase, HD subdomain: (1.1e-13); SMART: Metal-dependent phosphohydrolase, HD region: (7.1e-06); KEGG: dra:DR1565 hypothetical protein, ev=1e-123, 69% identity YP_604764.1 PFAM: protein of unknown function UPF0153: (0.00032); KEGG: gme:Gmet_2957 hypothetical protein, ev=5e-18, 28% identity YP_604765.1 KEGG: ttj:TTHA0317 hypothetical protein, ev=5e-12, 29% identity YP_604766.1 PFAM: protein of unknown function DUF6, transmembrane: (2.2e-22); KEGG: ttj:TTHA1661 conserved hypothetical protein, integral membrane protein, ev=6e-68, 55% identity YP_604767.1 KEGG: sma:SAV120 IS4 family transposase, ev=1e-91, 47% identity YP_604768.1 KEGG: dra:DR1740 hypothetical protein, ev=1e-171, 74% identity YP_604769.1 PFAM: phosphoglucose isomerase (PGI): (7.5e-272); KEGG: dra:DR1742 glucose-6-phosphate isomerase, ev=0.0, 77% identity YP_604770.1 PFAM: Thiolase: (4e-110); KEGG: dra:DRA0053 acetyl-CoA acetyltransferase, ev=0.0, 81% identity YP_604771.1 KEGG: dra:DRA0054 3-oxoacid CoA-transferase, ev=0.0, 82% identity; TIGRFAM: 3-oxoacid CoA-transferase, subunit B: (6.2e-137) 3-oxoacid CoA-transferase, subunit A: (4.9e-69); PFAM: coenzyme A transferase: (7.4e-43) YP_604772.1 PFAM: regulatory protein, TetR: (1.2e-11); KEGG: dra:DR1081 transcriptional regulator, TetR family, ev=3e-75, 71% identity YP_604773.1 KEGG: dra:DR1838 GTP pyrophosphokinase, ev=0.0, 77% identity; TIGRFAM: RelA/SpoT family protein: (2.9e-250); PFAM: amino acid-binding ACT: (2.1e-07) TGS: (6e-30) metal-dependent phosphohydrolase, HD subdomain: (1.3e-16) RelA/SpoT: (5.5e-48); SMART: Metal-dependent phosphohydrolase, HD region: (7.7e-15) YP_604774.1 PFAM: Ion transport 2: (1.2e-06); KEGG: dra:DR1911 hypothetical protein, ev=1e-75, 47% identity YP_604775.1 KEGG: dra:DR1454 hypothetical protein, ev=2e-51, 55% identity YP_604776.1 PFAM: regulatory protein, MerR: (0.00017); KEGG: dra:DR1455 hypothetical protein, ev=3e-28, 88% identity YP_604777.1 PFAM: protein of unknown function DUF554: (4.2e-106); KEGG: dra:DR1630 hypothetical protein, ev=1e-116, 81% identity YP_604778.1 PFAM: protein of unknown function DUF1648: (1e-08); KEGG: afu:AF2202 tryptophan-specific permease, , ev=3e-08, 30% identity YP_604779.1 PFAM: regulatory protein, ArsR: (1.2e-10); KEGG: mta:Moth_2084 transcriptional regulator, ArsR family, ev=5e-17, 49% identity YP_604780.1 PFAM: alpha/beta hydrolase fold: (2.9e-05) peptidase S15: (3.1e-05); KEGG: pfl:PFL_4349 hydrolase, alpha/beta fold family, ev=9e-58, 42% identity YP_604781.1 KEGG: dra:DR1115 S-layer-like array-related protein, ev=1e-156, 66% identity YP_604782.1 TIGRFAM: carboxynorspermidine decarboxylase: (9.3e-283); PFAM: Orn/DAP/Arg decarboxylase 2: (4.9e-29); KEGG: dra:DR1410 carboxynorspermidine decarboxylase, ev=0.0, 85% identity YP_604783.1 catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate YP_604784.1 PFAM: ribulose-phosphate 3-epimerase: (4.4e-103); KEGG: dra:DR1401 ribulose-phosphate 3-epimerase, ev=7e-95, 77% identity YP_604785.1 MDM; functions in conversion of succinate to propionate YP_604787.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_604788.1 KEGG: dra:DRB0118 dessication-associated protein, ev=5e-71, 51% identity YP_604789.1 NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways YP_604790.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_604791.1 PFAM: General substrate transporter: (6.6e-13) major facilitator superfamily MFS_1: (9.2e-34); KEGG: dra:DRA0271 sugar transporter , ev=0.0, 77% identity YP_604792.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_604793.1 PFAM: short-chain dehydrogenase/reductase SDR: (9.1e-30); KEGG: dra:DR1620 ketoacyl reductase, , ev=1e-104, 60% identity YP_604794.1 PFAM: histidine triad (HIT) protein: (4e-40); KEGG: dra:DR1621 Hit family protein, ev=1e-49, 81% identity YP_604795.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (2.8e-10) HAD-superfamily hydrolase, subfamily IA, variant 1: (0.00051); PFAM: Haloacid dehalogenase-like hydrolase: (1.6e-31); KEGG: dra:DR1622 beta-phosphoglucomutase-related protein, ev=8e-64, 59% identity YP_604796.1 TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit: (2.6e-67); PFAM: serine dehydratase alpha chain: (3.4e-152); KEGG: dra:DR0377 L-serine dehydratase, alpha subunit, ev=1e-149, 90% identity YP_604797.1 TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit: (4.6e-59); PFAM: amino acid-binding ACT: (0.0055) serine dehydratase beta chain: (5.9e-65); KEGG: dra:DR0497 L-serine dehydratase, beta subunit, ev=1e-102, 85% identity YP_604798.1 PFAM: Amidase: (1.7e-97); KEGG: dra:DR1625 amidase, , ev=1e-176, 68% identity YP_604799.1 PFAM: prephenate dehydratase: (1.5e-50) amino acid-binding ACT: (0.00036); KEGG: dra:DR1147 prephenate dehydratase, ev=1e-121, 76% identity YP_604800.1 KEGG: gsu:GSU1667 hypothetical protein, ev=4e-21, 53% identity YP_604801.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_604802.1 KEGG: dra:DR0968 5,10-methylenetetrahydrofolate reductase-related protein, ev=1e-104, 73% identity YP_604803.1 KEGG: dra:DR0969 hypothetical protein, ev=1e-148, 62% identity YP_604804.1 KEGG: dra:DR1567 peptide transport system ATP-binding protein, ev=1e-165, 86% identity; TIGRFAM: Oligopeptide/dipeptide ABC transporter ATP-binding protein-like: (4.5e-33); PFAM: ABC transporter related: (1.5e-64) Oligopeptide/dipeptide ABC transporter-like: (9.3e-32); SMART: ATPase: (1.7e-20) YP_604805.1 KEGG: dra:DR1568 peptide transport system ATP-binding protein, ev=1e-175, 88% identity; TIGRFAM: Oligopeptide/dipeptide ABC transporter ATP-binding protein-like: (9.9e-33); PFAM: ABC transporter related: (7.5e-64) Oligopeptide/dipeptide ABC transporter-like: (9.1e-32); SMART: ATPase: (1.5e-17) YP_604806.1 PFAM: binding-protein-dependent transport systems inner membrane component: (1.9e-39); KEGG: dra:DR1569 peptide transport system permease, ev=1e-139, 65% identity YP_604807.1 PFAM: binding-protein-dependent transport systems inner membrane component: (3.5e-41); KEGG: dra:DR1570 peptide transport system permease, ev=1e-107, 57% identity YP_604808.1 PFAM: extracellular solute-binding protein, family 5: (2.8e-79); KEGG: dra:DR1571 peptide transport system substrate-binding protein, ev=1e-158, 49% identity YP_604809.1 TIGRFAM: preprotein translocase, SecG subunit: (9.8e-20); PFAM: Preprotein translocase SecG subunit: (1.2e-19); KEGG: dra:DR1825 preprotein translocase SecG subunit, ev=3e-28, 87% identity YP_604810.1 PFAM: sigma-70 region 3: (2.1e-20) sigma-70 region 2: (2.7e-26) sigma-70 region 4: (3.8e-21) sigma-70 region 1.2: (3.2e-15); KEGG: dra:DR0916 RNA polymerase sigma-A factor, ev=1e-126, 68% identity YP_604811.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_604812.1 PFAM: beta-lactamase-like: (7.9e-25); KEGG: dra:DR1430 metallo-beta-lactamase-related protein, ev=1e-124, 71% identity YP_604813.1 KEGG: dra:DR1429 hypothetical protein, ev=2e-10, 61% identity YP_604814.1 KEGG: dra:DR1881 hypothetical protein, ev=3e-50, 79% identity YP_604815.1 KEGG: dra:DR1882 hypothetical protein, ev=2e-32, 50% identity YP_604816.1 PFAM: Amidase: (8.8e-66); KEGG: dra:DR1377 amidase, , ev=1e-158, 73% identity YP_604817.1 KEGG: dra:DR0330 hypothetical protein, ev=3e-11, 31% identity YP_604818.1 KEGG: dra:DR1484 hypothetical protein, ev=3e-35, 57% identity YP_604824.1 KEGG: dra:DRC0030 hypothetical protein, ev=1e-103, 50% identity YP_604830.1 PFAM: helix-turn-helix motif: (2.6e-09) peptidase S24, S26A and S26B: (9.8e-12); KEGG: det:DET0884 transcriptional repressor LexA, , ev=4e-09, 27% identity YP_604832.1 PFAM: Resolvase-like: (8e-05) Recombinase: (1.2e-11); KEGG: eba:ebA532 site-specific recombinases, ev=4e-14, 23% identity YP_604833.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_604834.1 PFAM: periplasmic binding protein: (3e-12); KEGG: dra:DRB0125 iron transport system substrate-binding protein, ev=1e-109, 62% identity YP_604836.1 PFAM: transposase IS66: (0.00029); KEGG: dra:DRC0028 transposase, , ev=1e-172, 86% identity YP_604838.1 PFAM: ABC transporter related: (9.7e-17); SMART: ATPase: (0.0042); KEGG: dra:DR0957 sugar ABC transporter ATP-binding protein, ev=0.0, 84% identity YP_604839.1 PFAM: phosphoesterase, PA-phosphatase related: (6.6e-19); KEGG: dra:DR0956 hypothetical protein, ev=3e-83, 63% identity YP_604840.1 PFAM: protein of unknown function DUF214: (9e-40); KEGG: dra:DR0474 hypothetical protein, ev=1e-151, 72% identity YP_604841.1 PFAM: ABC transporter related: (2.3e-62); SMART: ATPase: (1e-19); KEGG: dra:DR0473 ABC transporter ATP-binding protein, ev=1e-86, 76% identity YP_604842.1 KEGG: dra:DR1446 hypothetical protein, ev=4e-25, 50% identity YP_604843.1 KEGG: dra:DR1448 hypothetical protein, ev=1e-124, 65% identity YP_604844.1 KEGG: dra:DR1086 alanine racemase, ev=1e-143, 72% identity; TIGRFAM: alanine racemase: (3.5e-85); PFAM: alanine racemase-like: (4e-64) YP_604845.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_604846.1 KEGG: dra:DR1121 hypothetical protein, ev=5e-45, 80% identity YP_604847.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate YP_604848.1 TIGRFAM: ribosomal subunit interface protein: (1.3e-28); PFAM: sigma 54 modulation protein/ribosomal protein S30EA: (1.4e-39); KEGG: dra:DR1082 light-repressed protein A, , ev=2e-73, 74% identity YP_604849.1 PFAM: ABC transporter transmembrane region: (4.9e-60) ABC transporter related: (5e-66); SMART: ATPase: (1.5e-21); KEGG: dra:DRA0349 ABC transporter ATP-binding protein, ev=0.0, 77% identity YP_604850.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_604851.1 KEGG: dra:DR1872 hypothetical protein, ev=1e-27, 83% identity YP_604852.1 PFAM: NLP/P60: (3.8e-42) Peptidoglycan-binding LysM: (4.1e-16); KEGG: dra:DR1325 endopeptidase-related protein, ev=4e-75, 53% identity YP_604853.1 PFAM: protein of unknown function DUF894, DitE: (8.3e-09) major facilitator superfamily MFS_1: (3.9e-32); KEGG: dra:DR1324 transport protein, , ev=0.0, 78% identity YP_604854.1 PFAM: Citrate transporter: (3e-17) TrkA-C: (1.5e-13) TRAP C4-dicarboxylate transport system permease DctM subunit: (0.0025); KEGG: dra:DR1411 transporter sodium/sulfate symporter family, ev=0.0, 79% identity YP_604855.1 catalyzes N(2)-acetyl-L-lysine + H(2)O = acetate + L-lysine YP_604856.1 KEGG: dra:DR1414 hypothetical protein, ev=6e-34, 42% identity YP_604857.1 KEGG: dra:DR1432 hypothetical protein, ev=3e-11, 47% identity YP_604858.1 KEGG: dra:DR1656 Mg(2+) chelatase family protein, ev=0.0, 82% identity; TIGRFAM: Mg chelatase-related protein: (7e-220); PFAM: magnesium chelatase, ChlI subunit: (5.4e-149) ATPase associated with various cellular activities, AAA_5: (8.4e-05); SMART: ATPase: (3.8e-11) YP_604859.1 TIGRFAM: degV family protein: (1.7e-45); PFAM: DegV: (2.4e-45); KEGG: dra:DR1986 DegV protein, ev=1e-32, 34% identity YP_604860.1 TIGRFAM: twin-arginine translocation protein, TatA/E family: (5.5e-22); PFAM: sec-independent translocation protein mttA/Hcf106: (2.3e-20); KEGG: dra:DR0292 sec-independent protein translocase, ev=9e-28, 58% identity YP_604861.1 PFAM: protein kinase: (4.7e-40) Pyrrolo-quinoline quinone: (1.3e-05); SMART: Tyrosine protein kinase: (1.2e-12) Serine/threonine protein kinase: (1.5e-55); KEGG: dra:DR2518 serine/threonine protein kinase, , ev=0.0, 75% identity YP_604862.1 PFAM: FAD dependent oxidoreductase: (0.0015); KEGG: dra:DRA0363 P49 secreted protein, ev=1e-167, 62% identity YP_604863.1 KEGG: dra:DR1896 hypothetical protein, ev=3e-15, 50% identity YP_604864.1 KEGG: nfa:nfa48160 hypothetical protein, ev=2e-59, 38% identity YP_604865.1 PFAM: AAA ATPase, central region: (4.5e-22) ATPase associated with various cellular activities, AAA_5: (0.00052); SMART: ATPase: (6.7e-18); KEGG: dra:DR1898 ATPase, ev=0.0, 84% identity YP_604866.1 PFAM: aldo/keto reductase: (4.1e-72); KEGG: eca:ECA3182 probable oxidoreductase, ev=5e-74, 46% identity YP_604868.1 TIGRFAM: Orotidine 5'-phosphate decarboxylase subfamily 2: (7.9e-123); PFAM: Orotidine 5'-phosphate decarboxylase: (3.3e-39); KEGG: dra:DR2200 orotidine-5'-phosphate decarboxylase, ev=1e-118, 81% identity YP_604869.1 PFAM: protein of unknown function DUF1028: (8.9e-94); KEGG: ttj:TTHA1881 hypothetical protein, ev=1e-84, 58% identity YP_604870.1 PFAM: protein of unknown function UPF0074: (5e-39) Helix-turn-helix, type 11: (0.0037); KEGG: dra:DR2201 hypothetical protein, ev=2e-76, 89% identity YP_604871.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like: (1.1e-18) nitrite and sulphite reductase 4Fe-4S region: (2e-13); KEGG: dra:DRA0013 ferredoxin-nitrite reductase, ev=0.0, 78% identity YP_604872.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_604873.1 PFAM: phosphoadenosine phosphosulfate reductase: (5.5e-41); KEGG: dra:DRA0015 phosphoadenosine phosphosulfate reductase, ev=1e-112, 80% identity YP_604874.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms YP_604875.1 TIGRFAM: ABC transporter substrate-binding protein, aliphatic sulphonates: (2.2e-74); PFAM: NLPA lipoprotein: (6.3e-07); KEGG: dra:DR1277 sulfonate transport system substrate-binding protein, ev=1e-125, 72% identity YP_604876.1 PFAM: binding-protein-dependent transport systems inner membrane component: (8.4e-14); KEGG: dra:DR2197 sulfonate transport system permease, ev=1e-117, 77% identity YP_604877.1 PFAM: ABC transporter related: (6.6e-58); SMART: ATPase: (8.1e-23); KEGG: dra:DR2198 sulfonate transport system ATP-binding protein, ev=3e-87, 70% identity YP_604878.1 PFAM: transposase IS66: (0.00029); KEGG: dra:DRC0028 transposase, , ev=1e-172, 86% identity YP_604879.1 TIGRFAM: MATE efflux family protein: (5.9e-37); PFAM: multi antimicrobial extrusion protein MatE: (2.3e-24); KEGG: dra:DR0792 hypothetical protein, ev=1e-177, 72% identity YP_604880.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_604881.1 KEGG: dra:DR0837 hypothetical protein, ev=0.0, 75% identity YP_604882.1 PFAM: protein of unknown function DUF430: (5.7e-112); KEGG: dra:DR0836 hypothetical protein, ev=1e-100, 53% identity YP_604883.1 PFAM: cyclic nucleotide-binding: (1.4e-13) regulatory protein, Crp: (9.2e-05); KEGG: dra:DR0834 nitrogen regulator, , ev=7e-79, 73% identity YP_604884.1 PFAM: histone deacetylase superfamily: (2.1e-45); KEGG: dra:DR0833 histone deacetylase/AcuC/AphA family protein, ev=1e-132, 78% identity YP_604885.1 PFAM: PfkB: (1.4e-47); KEGG: dra:DR0728 fructokinase, ev=1e-134, 78% identity YP_604886.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_604887.1 PFAM: protein of unknown function DUF814: (1e-40) Fibronectin-binding A-like: (4.5e-87); KEGG: dra:DR0559 fibronectin/fibrinogen-binding protein, , ev=0.0, 74% identity YP_604888.1 PFAM: regulatory protein, MerR: (1.2e-06); KEGG: dra:DR2448 transcriptional regulator, MerR family, ev=2e-42, 41% identity YP_604889.1 PFAM: surface antigen (D15): (1.1e-40) surface antigen variable number: (1.7e-12) Polypeptide-transport-associated, ShlB-type: (2.6e-07); KEGG: dra:DR0379 outer membrane protein, ev=0.0, 64% identity YP_604890.1 TIGRFAM: Protein of unknown function UPF0001: (1.4e-15); KEGG: dra:DR1368 hypothetical protein, ev=2e-73, 68% identity YP_604891.1 PFAM: DivIVA: (1.1e-33); KEGG: dra:DR1369 minicell-associated protein DivIVA, ev=1e-58, 49% identity YP_604892.1 PFAM: RelA/SpoT: (1.7e-41); KEGG: dra:DR1631 hypothetical protein, ev=1e-133, 68% identity YP_604893.1 KEGG: dra:DR1786 hypothetical protein, ev=4e-32, 67% identity YP_604894.1 PFAM: regulatory protein GntR, HTH: (7.4e-18) aminotransferase, class I and II: (8.3e-08); KEGG: dra:DR1787 MocR protein, ev=1e-154, 64% identity YP_604895.1 KEGG: dra:DR1788 hypothetical protein, ev=4e-33, 56% identity YP_604896.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_604897.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_604898.1 PFAM: metallophosphoesterase: (1.2e-18); KEGG: dra:DR1119 hypothetical protein, ev=1e-100, 74% identity YP_604899.1 PFAM: protein of unknown function DUF125, transmembrane: (6.7e-19); KEGG: gox:GOX1978 hypothetical protein, ev=6e-45, 62% identity YP_604900.1 PFAM: luciferase-like: (1.2e-14); KEGG: sth:STH1269 bacterial luciferase-like monooxygenase, ev=9e-86, 49% identity YP_604901.1 KEGG: dra:DR1116 hypothetical protein, ev=1e-122, 72% identity YP_604902.1 PFAM: secretion protein HlyD: (0.00025); KEGG: dra:DR0739 hypothetical protein, ev=5e-36, 27% identity YP_604903.1 PFAM: acriflavin resistance protein: (4.8e-143); KEGG: dra:DR0740 drug transport protein, , ev=0.0, 45% identity YP_604904.1 KEGG: dra:DR1836 signal recognition particle protein, ev=0.0, 81% identity; TIGRFAM: signal recognition particle protein: (5.5e-261); PFAM: GTP-binding signal recognition particle SRP54, G-domain: (9.2e-105) Signal peptide binding (SRP54) M-domain: (3.6e-55); SMART: ATPase: (2.2e-11) YP_604905.1 PFAM: Thiolase: (6.2e-154); KEGG: dra:DR1072 acetyl-CoA acetyltransferase, ev=0.0, 82% identity YP_604906.1 PFAM: YCII-related: (8.2e-22); KEGG: dra:DR1071 hypothetical protein, ev=1e-39, 68% identity YP_604907.1 KEGG: sar:SAR2777 DNA-binding protein, ev=8e-08, 43% identity YP_604908.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase-like: (3e-55) 3-hydroxyacyl-CoA dehydrogenase, NAD-binding: (3.6e-93); KEGG: dra:DR1068 3-hydroxybutyryl-CoA dehydrogenase, ev=1e-133, 85% identity YP_604910.1 TIGRFAM: Alkylhydroperoxidase AhpD core: (4.7e-14) Uncharacterised peroxidase-related: (2.7e-97); PFAM: Carboxymuconolactone decarboxylase: (5e-10); KEGG: dra:DR1765 hypothetical protein, ev=6e-79, 75% identity YP_604911.1 PFAM: protein of unknown function DUF456: (3.2e-59); KEGG: dra:DR1441 hypothetical protein, ev=5e-62, 66% identity YP_604912.1 KEGG: dra:DR0858 hypothetical protein, ev=6e-26, 42% identity YP_604913.1 PFAM: protein of unknown function DUF1232: (1.2e-20); KEGG: reu:Reut_A1439 protein of unknown function DUF1232, ev=3e-29, 53% identity YP_604914.1 PFAM: Abortive infection protein: (7.2e-22); KEGG: dra:DR0857 hypothetical protein, ev=4e-79, 63% identity YP_604915.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase: (3.9e-148) aminotransferase, class I and II: (9.3e-06); KEGG: dra:DR1313 L-allo-threonine aldolase, ev=1e-150, 80% identity YP_604916.1 KEGG: sma:SAV2972 2-oxoglutarate dehydrogenase, ev=6e-06, 31% identity YP_604917.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_604918.1 TIGRFAM: conserved hypothetical protein: (2e-31); PFAM: PRC-barrel: (5.1e-15); KEGG: dra:DR1314 hypothetical protein, ev=1e-97, 65% identity YP_604919.1 KEGG: dra:DR1315 hypothetical protein, ev=4e-24, 42% identity YP_604920.1 PFAM: protein of unknown function DUF752: (1.7e-75); KEGG: dra:DR1672 hypothetical protein, ev=1e-81, 68% identity YP_604921.1 PFAM: FAD dependent oxidoreductase: (1.9e-24); KEGG: dra:DR1673 oxidoreductase, , ev=1e-107, 61% identity YP_604922.1 PFAM: isocitrate/isopropylmalate dehydrogenase: (4.2e-127); KEGG: dra:DR1674 isocitrate dehydrogenase, ev=1e-164, 86% identity YP_604923.1 KEGG: pfl:PFL_4721 hypothetical protein, ev=9e-42, 54% identity YP_604924.1 KEGG: tfu:Tfu_1651 conserved hypothetical membrane-anchored protein, ev=1e-19, 33% identity YP_604925.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_604926.1 KEGG: dra:DR1834 hypothetical protein, ev=1e-122, 68% identity YP_604928.1 KEGG: dra:DR1832 hypothetical protein, ev=2e-97, 80% identity YP_604929.1 KEGG: dra:DR1831 hypothetical protein, ev=9e-69, 49% identity YP_604930.1 KEGG: dra:DR1830 hypothetical protein, ev=2e-34, 52% identity YP_604931.1 PFAM: histidine kinase, HAMP region: (4.1e-19); KEGG: dra:DR1829 hypothetical protein, ev=4e-90, 41% identity YP_604932.1 KEGG: dra:DR1221 hypothetical protein, ev=7e-75, 63% identity YP_604933.1 PFAM: cytochrome c, class I: (3.6e-07); KEGG: dra:DR2487 cytochrome c4, , ev=1e-62, 54% identity YP_604934.1 KEGG: dra:DR1312 hypothetical protein, ev=2e-28, 71% identity YP_604935.1 PFAM: protein of unknown function DUF1517: (3.3e-139); KEGG: dra:DR1616 hypothetical protein, ev=1e-127, 77% identity YP_604936.1 KEGG: dra:DR1615 hypothetical protein, ev=9e-38, 64% identity YP_604937.1 PFAM: Late embryogenesis abundant protein: (4.5e-09); KEGG: dra:DR1172 hypothetical protein, ev=2e-56, 51% identity YP_604938.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_604939.1 PFAM: AAA ATPase, central region: (4.1e-12) Clp, N terminal: (0.072) ATPase associated with various cellular activities, AAA_5: (0.00011) ATPase AAA-2: (7.2e-81); SMART: ATPase: (1.4e-14); KEGG: dra:DR0588 ATP-dependent Clp protease, ATP-binding subunit ClpA, ev=0.0, 79% identity YP_604940.1 PFAM: oxidoreductase-like: (4.1e-36) Oxidoreductase-like: (6.4e-09); KEGG: dra:DR0799 glucose-fructose oxidoreductase, ev=1e-156, 71% identity YP_604941.1 PFAM: GCN5-related N-acetyltransferase: (4.2e-08); KEGG: dra:DR0796 acetyltransferase, , ev=5e-73, 71% identity YP_604942.1 KEGG: dra:DR0795 hypothetical protein, ev=7e-71, 66% identity YP_604943.1 KEGG: dra:DR1551 carboxyl-terminal protease, , ev=1e-168, 66% identity; TIGRFAM: carboxyl-terminal protease: (6.7e-72); PFAM: PDZ/DHR/GLGF: (8.3e-08) peptidase S41: (8.6e-70) YP_604944.1 KEGG: dra:DR1550 ftsE protein, ev=1e-100, 74% identity; TIGRFAM: Cell division ATP-binding protein FtsE: (3.5e-130); PFAM: ABC transporter related: (4.3e-49); SMART: ATPase: (4.4e-17) YP_604945.1 PFAM: protein of unknown function DUF214: (6.2e-26); KEGG: dra:DR1550 ftsE protein, ev=1e-107, 71% identity YP_604946.1 PFAM: peptidase M23B: (7.7e-09); KEGG: dra:DR1549 hypothetical protein, ev=1e-142, 52% identity YP_604947.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_604948.1 KEGG: dra:DR2009 hypothetical protein, ev=1e-34, 90% identity YP_604949.1 Essential for efficient processing of 16S rRNA YP_604950.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_604951.1 PFAM: peptidase S16, lon-like: (1.3e-07); KEGG: dra:DR2189 hypothetical protein, ev=6e-46, 55% identity YP_604952.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_604953.1 PFAM: peptidase M29, aminopeptidase II: (6.8e-12); KEGG: dra:DR0585 aminopeptidase, ev=1e-151, 74% identity YP_604954.1 PFAM: peptidase C39, bacteriocin processing: (0.00011); KEGG: dvu:DVU2613 hypothetical protein, ev=3e-07, 25% identity YP_604955.1 PFAM: SNF2-related: (1e-70) helicase-like: (3.2e-21); SMART: DEAD/DEAH box helicase-like: (3.5e-30); KEGG: dar:Daro_3870 SNF2-related:helicase, C-terminal:SWIM Zn-finger, ev=0.0, 45% identity YP_604956.1 TIGRFAM: peptide chain release factor 3: (6.4e-241) Small GTP-binding protein domain: (8.1e-20); PFAM: protein synthesis factor, GTP-binding: (3.8e-69) elongation factor Tu, domain 2: (7.6e-10); KEGG: dra:DR1553 peptide chain release factor RF-3, ev=0.0, 91% identity YP_604957.1 KEGG: cvi:CV4048 probable 2-nitropropane dioxygenase, ev=1e-28, 50% identity YP_604958.1 PFAM: 2-nitropropane dioxygenase, NPD: (1.5e-10); KEGG: sil:SPOA0325 oxidoreductase, 2-nitropropane dioxygenase family, ev=2e-46, 51% identity YP_604959.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap: (1.5e-06); SMART: PDZ/DHR/GLGF: (9.8e-15); KEGG: gvi:glr3741 serine protease, ev=6e-35, 33% identity YP_604960.1 PFAM: regulatory protein, LuxR: (8.9e-20) Sigma-70, region 4 type 2: (0.0037); KEGG: sco:SCO5455 two-component system response regulator, ev=2e-16, 34% identity YP_604961.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_604962.1 PFAM: Fmu (Sun): (9e-14) NusB/RsmB/TIM44: (4.9e-28); KEGG: dra:DR2168 sun protein, , ev=1e-161, 72% identity YP_604963.1 PFAM: major facilitator superfamily MFS_1: (1.9e-64); KEGG: dra:DR2169 drug transport protein, ev=1e-159, 70% identity YP_604964.1 PFAM: extracellular solute-binding protein, family 1: (1.3e-32); KEGG: dra:DR0561 maltose transport system substrate-binding protein, ev=1e-166, 70% identity YP_604965.1 PFAM: binding-protein-dependent transport systems inner membrane component: (2.1e-13); KEGG: dra:DR0562 maltose transport system permease, ev=0.0, 72% identity YP_604966.1 PFAM: binding-protein-dependent transport systems inner membrane component: (1.1e-19); KEGG: dra:DR0563 maltose transport system permease, ev=0.0, 76% identity YP_604968.1 PFAM: ATPase associated with various cellular activities, AAA_5: (0.00072); SMART: ATPase: (1.3e-06); KEGG: hpy:HP0452 hypothetical protein, ev=3e-18, 26% identity YP_604969.1 TIGRFAM: Protein of unknown function DUF11: (5.1e-06); KEGG: ttj:TTHA1874 hypothetical protein, ev=5e-81, 34% identity YP_604970.1 PFAM: glycerophosphoryl diester phosphodiesterase: (9.1e-66); KEGG: dra:DR2084 glycerophosphoryl diester phosphodiesterase, ev=1e-114, 72% identity YP_604971.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_604972.1 TIGRFAM: Glutaredoxin-like protein, YruB: (1.8e-42); PFAM: glutaredoxin: (4.7e-19); KEGG: dra:DR2085 glutaredoxin, , ev=6e-37, 90% identity YP_604973.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_604974.1 PFAM: NUDIX hydrolase: (1.2e-16); KEGG: dra:DR0192 MutT/NUDIX family protein, ev=1e-102, 81% identity YP_604976.1 PFAM: conserved hypothetical protein 103: (6.3e-39); KEGG: dra:DR0199 hypothetical protein, ev=2e-37, 83% identity YP_604977.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_604978.1 PFAM: GCN5-related N-acetyltransferase: (0.0067); KEGG: dra:DR0197 hypothetical protein, ev=2e-67, 68% identity YP_604980.1 PFAM: Peptidoglycan-binding LysM: (8.1e-21) peptidase M23B: (4.7e-48); KEGG: dra:DR0848 lipoprotein, , ev=1e-137, 65% identity YP_604981.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_604982.1 KEGG: dra:DR0889 hypothetical protein, ev=6e-29, 81% identity YP_604983.1 PFAM: sigma-70 region 2: (4.1e-17) sigma-70 region 4: (9.5e-16) Sigma-70, region 4 type 2: (6.2e-19); KEGG: dra:DR0180 RNA polymerase sigma-E factor, ev=1e-81, 80% identity YP_604984.1 PFAM: FUN14: (2.2e-18); KEGG: dra:DR0193 hypothetical protein, ev=1e-26, 50% identity YP_604985.1 PFAM: ATP-binding region, ATPase-like: (3.6e-38) histidine kinase, HAMP region: (9.7e-16) histidine kinase A-like: (1.8e-13); KEGG: det:DET1059 sensor histidine kinase, ev=3e-52, 37% identity YP_604986.1 PFAM: response regulator receiver: (9.8e-37) transcriptional regulatory protein-like: (6.3e-22); KEGG: bja:bll3559 two-component response regulator, ev=1e-58, 53% identity YP_604987.1 PFAM: outer membrane efflux protein: (1e-09); KEGG: tth:TTC0645 hypothetical protein, ev=8e-40, 33% identity YP_604988.1 KEGG: dra:DR0738 hypothetical protein, ev=2e-66, 44% identity YP_604989.1 PFAM: peptidase M22, glycoprotease: (1.6e-42); KEGG: dra:DR0756 hypothetical protein, ev=5e-62, 65% identity YP_604990.1 KEGG: dra:DR0757 citrate synthase, ev=0.0, 84% identity; TIGRFAM: 2-methylcitrate synthase/citrate synthase II: (1.1e-247); PFAM: Citrate synthase: (4.7e-142) YP_604991.1 KEGG: dra:DR2077 hypothetical protein, ev=2e-58, 71% identity YP_604992.1 PFAM: beta-lactamase-like: (8.7e-26); KEGG: dra:DR2076 hypothetical protein, ev=1e-145, 79% identity YP_604993.1 TIGRFAM: Protein of unknown function UPF0025: (3.5e-20); PFAM: metallophosphoesterase: (3.1e-10); KEGG: pae:PA0351 hypothetical protein, ev=7e-34, 48% identity YP_604994.1 KEGG: dra:DR1768 hypothetical protein, ev=6e-62, 86% identity YP_604995.1 PFAM: Pyrrolo-quinoline quinone: (5.5e-06); KEGG: dra:DR1769 serine/threonine protein kinase-related protein, ev=1e-160, 55% identity YP_604996.1 KEGG: dra:DR0909 hypothetical protein, ev=2e-42, 50% identity YP_604997.1 PFAM: cyclase: (5.6e-42); KEGG: pae:PA2081 hypothetical protein, ev=1e-42, 46% identity YP_604998.1 TIGRFAM: kynureninase: (1.6e-120); PFAM: aminotransferase, class V: (7.7e-10); KEGG: btk:BT9727_2523 kynureninase, ev=8e-99, 46% identity YP_604999.1 PFAM: thioesterase superfamily: (2.1e-05); KEGG: pca:Pcar_2293 hypothetical protein, ev=4e-15, 38% identity YP_605000.1 PFAM: transcriptional coactivator/pterin dehydratase: (1.2e-11); KEGG: nph:NP1766A homolog to 4A-hydroxytetrahydrobiopterin dehydratase, ev=1e-11, 37% identity YP_605001.1 This protein performs the mismatch recognition step during the DNA repair process YP_605002.1 TIGRFAM: DNA mismatch repair protein MutL: (1.2e-94); PFAM: ATP-binding region, ATPase-like: (8.5e-07) DNA mismatch repair protein-like: (2.2e-18); KEGG: dra:DR1696 DNA mismatch repair protein MutL, ev=0.0, 81% identity YP_605003.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_605004.1 SMART: WD-40 repeat: (0.45); KEGG: ana:all0438 serine/threonine kinase with WD-40 repeat, ev=4e-16, 23% identity YP_605005.1 TIGRFAM: methylmalonyl-CoA mutase C-terminal domain: (5.3e-45); PFAM: cobalamin B12-binding: (1.7e-41); KEGG: dra:DR2032 methylmalonyl-CoA mutase, alpha subunit, chain B, ev=1e-60, 85% identity YP_605006.1 PFAM: major facilitator superfamily MFS_1: (3.6e-14); KEGG: dra:DR2031 hypothetical protein, ev=1e-103, 73% identity YP_605007.1 PFAM: helicase-like: (1.8e-19) DEAD/DEAH box helicase-like: (1.7e-26); KEGG: dra:DRB0135 RNA helicase, , ev=0.0, 58% identity YP_605008.1 PFAM: SNF2-related: (0.00013) helicase-like: (1.7e-20); SMART: DEAD/DEAH box helicase-like: (4.7e-21); KEGG: dra:DRB0136 ATP-dependent helicase HepA, ev=0.0, 65% identity YP_605009.1 KEGG: tfu:Tfu_0724 type II DNA modification enzyme, ev=0.0, 43% identity YP_605010.1 PFAM: formyl transferase-like: (3.1e-40); KEGG: dra:DR2026 phosphoribosylglycinamide formyltransferase, ev=1e-78, 80% identity YP_605011.1 PFAM: peptidase M20: (5.3e-41) peptidase dimerisation: (7.3e-34); KEGG: dra:DR2025 ArgE/DapE/Acy1 family protein, ev=0.0, 80% identity YP_605012.1 PFAM: regulatory protein, MerR: (1.4e-06); KEGG: dra:DR0934 transcriptional regulator, MerR family, ev=1e-113, 86% identity YP_605013.1 PFAM: metallophosphoesterase: (6.3e-14); KEGG: dra:DR0935 phosphatase, , ev=3e-84, 57% identity YP_605014.1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis YP_605015.1 KEGG: dra:DR1372 hypothetical protein, ev=3e-44, 55% identity YP_605016.1 KEGG: dra:DR1371 hypothetical protein, ev=3e-50, 41% identity YP_605017.1 KEGG: dra:DR1370 hypothetical protein, ev=8e-75, 70% identity YP_605018.1 PFAM: NLP/P60: (1.1e-33) Peptidoglycan-binding LysM: (4.3e-20); KEGG: dra:DR1749 endopeptidase-related protein, ev=2e-71, 64% identity YP_605019.1 KEGG: dra:DR1750 hypothetical protein, ev=2e-49, 75% identity YP_605020.1 TIGRFAM: phage SPO1 DNA polymerase-related protein: (8.2e-56); PFAM: Uracil-DNA glycosylase superfamily: (6.3e-40); KEGG: dra:DR1751 DNA polymerase-related protein, ev=7e-78, 69% identity YP_605021.1 PFAM: PKD: (6.6e-07) Allergen V5/Tpx-1 related: (1e-17); KEGG: dra:DR1009 hypothetical protein, ev=2e-26, 37% identity YP_605022.1 PFAM: ATP-binding region, ATPase-like: (4.7e-33) histidine kinase A-like: (0.0025); KEGG: xoo:XOO1106 two-component system sensor protein, ev=6e-26, 36% identity YP_605023.1 KEGG: vvu:VV20930 hypothetical protein, ev=1e-08, 33% identity YP_605024.1 KEGG: dra:DR0383 S-layer-like array-related protein, ev=8e-69, 47% identity YP_605025.1 PFAM: dehydrogenase, E1 component: (1.1e-110); KEGG: tth:TTC0569 pyruvate decarboxylase alpha subunit-like protein, ev=4e-89, 53% identity YP_605026.1 PFAM: Transketolase, central region: (3.3e-66) Transketolase-like: (6.9e-47); KEGG: ttj:TTHA0938 pyruvate dehydrogenase E1 component, beta subunit, ev=1e-125, 67% identity YP_605027.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_605028.1 KEGG: dps:DP0608 hypothetical protein, ev=2e-35, 33% identity YP_605029.1 PFAM: 60 kDa inner membrane insertion protein: (3.6e-88); KEGG: dra:DR2149 inner membrane protein, 60 kDa, , ev=1e-180, 74% identity YP_605030.1 PFAM: protein of unknown function DUF37: (4e-34); KEGG: dra:DR2150 conserved hypothetical protein, ev=3e-31, 75% identity YP_605031.1 TIGRFAM: ribonuclease P protein component: (2.2e-11); PFAM: ribonuclease P protein: (8.7e-05); KEGG: dra:DR2151 ribonuclease P protein component, ev=2e-43, 62% identity YP_605032.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_605033.1 PFAM: protein of unknown function DUF59: (1e-33); KEGG: dra:DR0998 mrp protein, ev=1e-161, 82% identity YP_605034.1 PFAM: regulatory protein, MarR: (0.0033) regulatory protein, DeoR: (0.002) regulatory protein, ArsR: (1.1e-06) transcriptional regulator PadR-like: (0.00018) Helix-turn-helix, type 11: (0.00023); KEGG: dra:DR0999 hypothetical protein, ev=1e-57, 57% identity YP_605035.1 KEGG: dra:DR1000 hypothetical protein, ev=4e-63, 65% identity YP_605036.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_605037.1 PFAM: globin: (7.3e-31); KEGG: dra:DR1002 hypothetical protein, ev=1e-52, 77% identity YP_605038.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_605039.1 PFAM: metal-dependent phosphohydrolase, HD subdomain: (0.00028); KEGG: dra:DR1981 hypothetical protein, ev=2e-61, 70% identity YP_605040.1 TIGRFAM: thioredoxin reductase: (2.6e-169); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (1.4e-26) HI0933-like protein: (0.0055) FAD dependent oxidoreductase: (0.0013); KEGG: dra:DR1982 thioredoxin reductase, ev=1e-149, 79% identity YP_605041.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_605042.1 PFAM: oxidoreductase-like: (5e-36) Oxidoreductase-like: (2.5e-06); KEGG: bcl:ABC2696 oxidoreductase, ev=1e-43, 36% identity YP_605043.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2: (7e-56); PFAM: beta-lactamase-like: (1.2e-06) ComEC/Rec2-related protein: (5.8e-44); KEGG: dra:DR1854 competence protein ComEC/Rec2, , ev=0.0, 68% identity YP_605044.1 PFAM: protein of unknown function DUF6, transmembrane: (5.4e-16); KEGG: ppu:PP4767 transporter , ev=8e-79, 54% identity YP_605045.1 KEGG: lxx:Lxx14250 hypothetical protein, ev=6e-10, 43% identity YP_605046.1 PFAM: RNA methylase: (9e-65) Methyltransferase type 11: (9.6e-07); KEGG: dra:DR1669 hypothetical protein, ev=1e-152, 72% identity YP_605047.1 TIGRFAM: K+ transporter Trk: (1.6e-150); PFAM: cation transporter: (2.9e-81); KEGG: dra:DR1668 potassium uptake protein KtrB, ev=1e-155, 60% identity YP_605048.1 PFAM: TrkA-N: (2.2e-38) TrkA-C: (1.4e-11) NAD-dependent glycerol-3-phosphate dehydrogenase-like: (0.00032); KEGG: dra:DR1666 potassium uptake protein KtrA, ev=1e-108, 92% identity YP_605049.1 KEGG: dra:DR1665 hypothetical protein, ev=1e-27, 48% identity YP_605050.1 PFAM: beta-lactamase-like: (3.3e-10); KEGG: rba:RB11859 PhnP protein homolog- hydrolase, ev=4e-21, 34% identity YP_605051.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_605052.1 KEGG: dra:DR1376 hypoxanthine-guanine phosphoribosyltransferase, ev=5e-81, 84% identity; TIGRFAM: hypoxanthine phosphoribosyltransferase: (4.1e-101); PFAM: phosphoribosyltransferase: (8.8e-32) YP_605053.1 KEGG: pfo:Pfl_2193 arsenical pump membrane protein, ev=3e-24, 56% identity YP_605054.1 PFAM: Arsenical pump membrane protein: (2e-10); KEGG: pfl:PFL_3288 arsenical pump membrane protein, ev=4e-51, 47% identity YP_605055.1 KEGG: dra:DR2172 hypothetical protein, ev=4e-25, 42% identity YP_605056.1 KEGG: dra:DR1269 hypothetical protein, ev=4e-35, 57% identity YP_605057.1 PFAM: VanW: (7.4e-68); KEGG: dra:DR1619 hypothetical protein, ev=1e-177, 62% identity YP_605058.1 KEGG: dra:DR1443 hypothetical protein, ev=1e-147, 77% identity YP_605059.1 PFAM: Enoyl-CoA hydratase/isomerase: (8.6e-67); KEGG: dra:DR1151 3-hydroxybutyryl-CoA dehydratase, ev=1e-108, 73% identity YP_605060.1 PFAM: purine and other phosphorylases, family 1: (1.1e-55); KEGG: ttj:TTHA1435 purine nucleoside phosphorylase, ev=1e-74, 61% identity YP_605061.1 PFAM: S-layer-like region: (6.3e-20); KEGG: dra:DR1124 SLH family protein, ev=1e-115, 56% identity YP_605062.1 KEGG: dra:DR1125 hypothetical protein, ev=2e-25, 61% identity YP_605063.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ: (3.4e-131); PFAM: phosphoesterase, RecJ-like: (2.1e-42) phosphoesterase, DHHA1: (4.6e-10); KEGG: dra:DR1126 single-stranded-DNA-specific exonuclease, , ev=0.0, 68% identity YP_605064.1 KEGG: dra:DR1852 hypothetical protein, ev=1e-113, 63% identity YP_605065.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase: (1.1e-05); KEGG: dra:DR0071 peptidyl-prolyl cis-trans isomerse, , PpiC family, ev=0.0, 58% identity YP_605066.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_605067.1 KEGG: dra:DR0557 hypothetical protein, ev=4e-76, 64% identity YP_605068.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_605069.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_605070.1 PFAM: protein of unknown function DUF6, transmembrane: (6.2e-12); KEGG: dra:DR0135 hypothetical protein, ev=1e-119, 76% identity YP_605071.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_605072.1 catalyzes the formation of L-histidinol from L-histidinol phosphate YP_605073.1 PFAM: PHP-like: (6.9e-37); SMART: DNA polymerase X: (3.2e-07) Phosphoesterase PHP-like: (6.5e-09); KEGG: dra:DR0467 hypothetical DNA polymerase / histidinol phosphatase, ev=0.0, 64% identity YP_605074.1 PFAM: major facilitator superfamily MFS_1: (7.2e-48); KEGG: dra:DR1743 fosmidomycin resistance protein, , ev=0.0, 83% identity YP_605075.1 KEGG: dra:DR1744 hypothetical protein, ev=2e-27, 43% identity YP_605076.1 PFAM: Isoprenylcysteine carboxyl methyltransferase: (4.8e-41); KEGG: dra:DR1745 hypothetical protein, ev=3e-69, 71% identity YP_605077.1 TIGRFAM: LAO/AO transport system ATPase: (2.3e-90); PFAM: ArgK protein: (2.4e-147); KEGG: dra:DR1747 LAO/AO transport system kinase, ev=1e-136, 80% identity YP_605078.1 TIGRFAM: PAS: (6e-07) GGDEF domain: (6e-53); PFAM: GGDEF: (1.5e-59) PAS fold-4: (1.4e-05) PAS fold: (1.9e-09); KEGG: cvi:CV0964 hypothetical protein, ev=3e-74, 35% identity YP_605079.1 PFAM: Phosphoglycerate mutase: (3.4e-53); KEGG: dra:DR1393 phosphoglycerate mutase, ev=1e-102, 79% identity YP_605080.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_605081.1 KEGG: noc:Noc_1842 conserved hypothetical protein, DedA-like, ev=3e-21, 30% identity YP_605082.1 PFAM: Polyprenyl synthetase: (4.2e-30); KEGG: dra:DR1395 dimethylallyltranstransferase / geranyltranstransferase, ev=1e-132, 73% identity YP_605083.1 PFAM: N-formylglutamate amidohydrolase: (2.6e-57); KEGG: dra:DR1397 hypothetical protein, ev=2e-99, 71% identity YP_605084.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_605085.1 KEGG: dra:DR1088 hypothetical protein, ev=1e-96, 63% identity YP_605086.1 PFAM: conserved hypothetical protein 95: (3.7e-05) methyltransferase small: (1.1e-63) Methyltransferase type 11: (1.3e-07) Methyltransferase type 12: (3.9e-10); KEGG: dra:DR0914 hypothetical protein, ev=1e-130, 78% identity YP_605087.1 cleaves the the RNA-DNA junction of a RNA-DNA/DNA heteroduplex; does not have RNase H activity YP_605088.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_605089.1 PFAM: ATP-binding region, ATPase-like: (2.1e-11) histidine kinase, HAMP region: (1.2e-05) histidine kinase A-like: (2.5e-06); KEGG: dra:DR0892 sensor histidine kinase, ev=1e-104, 60% identity YP_605090.1 PFAM: regulatory protein, LuxR: (1.2e-22) response regulator receiver: (1.4e-32) Bacterio-opsin activator, HTH: (0.00096) Sigma-70, region 4 type 2: (0.00043); KEGG: dra:DR0891 DNA-binding response regulator, ev=2e-92, 87% identity YP_605091.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes: (0.0031) DegT/DnrJ/EryC1/StrS aminotransferase: (1.9e-05) aromatic amino acid beta-eliminating lyase/threonine aldolase: (7.6e-05) aminotransferase, class I and II: (2.2e-104); KEGG: dra:DR0623 aspartate aminotransferase, ev=0.0, 84% identity YP_605092.1 PFAM: nitroreductase: (2.5e-16); KEGG: pae:PA3208 hypothetical protein, ev=6e-20, 38% identity YP_605093.1 PFAM: protein of unknown function DUF124: (8.9e-79); KEGG: dra:DR0625 hypothetical protein, ev=1e-121, 88% identity YP_605094.1 KEGG: dra:DR0626 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, ev=1e-142, 68% identity; TIGRFAM: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase: (5e-91); PFAM: glycosyl transferase, family 28: (3.1e-42) glycosyltransferase 28-like: (3.8e-37) YP_605095.1 TIGRFAM: UDP-N-acetylmuramate--alanine ligase: (2.9e-199); PFAM: cytoplasmic peptidoglycan synthetase-like: (9.2e-29) cytoplasmic peptidoglycan synthetases-like: (8.3e-12) Mur ligase, middle region: (1.3e-12); KEGG: dra:DR0627 UDP-N-acetylmuramate--alanine ligase, ev=0.0, 73% identity YP_605096.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_605097.1 PFAM: Polypeptide-transport-associated, FtsQ-type: (9.7e-18); KEGG: dra:DR0629 cell division protein FtsQ-related protein, ev=1e-65, 55% identity YP_605098.1 PFAM: cell division protein FtsA: (4.9e-63); KEGG: dra:DR0630 cell division protein FtsA, ev=1e-177, 79% identity YP_605099.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_605100.1 PFAM: Extracellular ligand-binding receptor: (9.3e-49); KEGG: dra:DR1038 branched-chain amino acid transport system substrate-binding protein, ev=1e-123, 60% identity YP_605101.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_605102.1 TIGRFAM: Protein of unknown function UPF0011: (1.6e-61); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase: (2e-37); KEGG: dra:DR0636 hypothetical protein, ev=1e-108, 77% identity YP_605103.1 KEGG: dra:DR0637 hypothetical protein, ev=8e-18, 71% identity YP_605104.1 KEGG: dra:DR0638 hypothetical protein, ev=5e-52, 72% identity YP_605105.1 PFAM: protein of unknown function DUF163: (1.4e-59); KEGG: dra:DR0619 hypothetical protein, ev=3e-62, 78% identity YP_605107.1 PFAM: peptidase M16-like: (1.2e-13) Peptidase M16C associated: (1.1e-90); KEGG: dra:DR0617 metalloprotease, , ev=0.0, 75% identity YP_605108.1 PFAM: Ig: (1.7e-05); KEGG: dra:DR1407 hypothetical protein, ev=6e-70, 49% identity YP_605109.1 KEGG: dra:DR1406 hypothetical protein, ev=1e-38, 59% identity YP_605110.1 KEGG: dra:DR1405 hypothetical protein, ev=2e-25, 62% identity YP_605111.1 PFAM: RNA-binding S4: (6.1e-05); KEGG: dra:DR1391 hypothetical protein, ev=1e-24, 83% identity YP_605112.1 PFAM: protein of unknown function DUF1684: (2.2e-51); KEGG: dra:DR1390 hypothetical protein, ev=2e-61, 62% identity YP_605113.1 TIGRFAM: Peptidase S26A, signal peptidase I: (1.7e-52); PFAM: peptidase S24, S26A and S26B: (7.3e-11); KEGG: dra:DR1321 signal peptidase I, ev=3e-67, 68% identity YP_605114.1 PFAM: peptidylprolyl isomerase, FKBP-type: (9.5e-55); KEGG: dra:DR1839 peptidyl-prolyl cis-trans isomerase, FKBP-type, ev=2e-49, 79% identity YP_605115.1 KEGG: dra:DR1840 hypothetical protein, ev=2e-16, 64% identity YP_605116.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase: (3.7e-118); KEGG: dra:DR0403 inosine-uridine preferring nucleoside hydrolase, ev=1e-121, 71% identity YP_605117.1 PFAM: Mov34/MPN/PAD-1: (0.0011); KEGG: dra:DR0402 hypothetical protein, ev=2e-38, 64% identity YP_605118.1 PFAM: cell divisionFtsK/SpoIIIE: (2.8e-74); SMART: ATPase: (1.8e-08); KEGG: dra:DR0400 cell division protein FtsK, , ev=0.0, 77% identity YP_605119.1 PFAM: beta-Ig-H3/fasciclin: (7.3e-37); KEGG: dra:DR0399 osteoblast specific factor 2-related protein, ev=1e-142, 48% identity YP_605120.1 PFAM: metallophosphoesterase: (3.2e-21); KEGG: dra:DR0761 hypothetical protein, ev=1e-109, 70% identity YP_605121.1 TIGRFAM: cysteine synthases: (8.1e-200) cysteine synthase A: (4.6e-208); PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit: (2.9e-117); KEGG: dra:DR0789 O-acetylserine (thiol)-lyase, ev=1e-153, 83% identity YP_605122.1 KEGG: dra:DR0201 hypothetical protein, ev=1e-73, 56% identity YP_605123.1 PFAM: polysaccharide deacetylase: (3.2e-13); KEGG: gme:Gmet_2023 polysaccharide deacetylase, ev=5e-12, 29% identity YP_605124.1 TIGRFAM: DNA-3-methyladenine glycosylase: (7.4e-32); PFAM: methylpurine-DNA glycosylase (MPG): (1.8e-32); KEGG: dra:DR2074 3-methyladenine DNA glycosylase, ev=3e-77, 72% identity YP_605125.1 KEGG: dra:DR2072 hypothetical protein, ev=1e-156, 75% identity YP_605126.1 PFAM: aminoglycoside phosphotransferase: (2e-07) YP_605128.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_605129.1 PFAM: Ig-like, group 2: (1.2e-13); KEGG: bja:bll6031 zinc metalloendopeptidase, ev=2e-49, 50% identity YP_605130.1 KEGG: dra:DR1707 DNA-directed DNA polymerase, ev=0.0, 71% identity; TIGRFAM: DNA polymerase I: (0); PFAM: DNA-directed DNA polymerase: (2.2e-201) 5'-3' exonuclease: (1e-40); SMART: Helix-hairpin-helix motif, class 2: (1.5e-14) YP_605131.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (6.8e-07); PFAM: Haloacid dehalogenase-like hydrolase: (1.3e-11); KEGG: dra:DR1705 hydrolase family protein, ev=2e-81, 76% identity YP_605132.1 KEGG: gvi:gll4351 WD-repeat protein, ev=2e-12, 28% identity YP_605133.1 KEGG: sec:SC1300 aldehyde reductase, ev=5e-26, 51% identity YP_605134.1 PFAM: protein of unknown function DUF970: (4.9e-58); KEGG: dra:DR1423 hypothetical protein, ev=2e-33, 68% identity YP_605135.1 KEGG: dra:DR1422 hypothetical protein, ev=2e-75, 86% identity YP_605136.1 SMART: PAS: (0.0052) YP_605137.1 PFAM: IS1 transposase: (7.4e-22); KEGG: sru:SRU_2704 ISSru3, transposase InsB, ev=1e-21, 41% identity YP_605138.1 PFAM: GGDEF: (4.3e-08); KEGG: syn:slr0359 hypothetical protein, ev=8e-16, 31% identity YP_605139.1 PFAM: ABC transporter related: (3.2e-50); SMART: ATPase: (5.5e-13); KEGG: dra:DR0927 sodium extrusion transport system ATP-binding protein, ev=7e-99, 78% identity YP_605140.1 PFAM: ABC-2 type transporter: (0.0015); KEGG: dra:DR0926 sodium extrusion transport system permease, ev=1e-140, 65% identity YP_605141.1 PFAM: PRC-barrel: (2.3e-13); KEGG: dra:DR0894 hypothetical protein, ev=1e-110, 42% identity YP_605142.1 KEGG: dra:DR1870 hypothetical protein, ev=9e-89, 68% identity YP_605143.1 PFAM: Mandelate racemase/muconate lactonizing enzyme-like: (2.4e-06); KEGG: dra:DR1871 chloromuconate cycloisomerase, , ev=1e-154, 79% identity YP_605145.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin: (1.4e-27); KEGG: dra:DRA0064 serine protease, subtilase family, ev=1e-100, 49% identity YP_605146.1 Catalyzes the conversion of citrate to isocitrate YP_605148.1 PFAM: chalcone and stilbene synthases-like: (1.1e-07) Chalcone and stilbene synthases-like: (6.6e-18) FAE1/Type III polyketide synthase-like protein: (0.00014) 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal: (2.9e-09); KEGG: dra:DR2091 chalcone synthase, , ev=1e-152, 77% identity YP_605149.1 PFAM: aldo/keto reductase: (1.3e-42); KEGG: dra:DR1890 oxidoreductase, , ev=1e-138, 83% identity YP_605150.1 PFAM: nitroreductase: (1.3e-06); KEGG: dra:DR1271 hypothetical protein, ev=1e-129, 85% identity YP_605151.1 KEGG: dra:DR1272 hypothetical protein, ev=7e-36, 75% identity YP_605152.1 KEGG: dra:DR0072 hypothetical protein, ev=4e-32, 52% identity YP_605153.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_605154.1 PFAM: inner-membrane translocator: (2.5e-45); KEGG: dra:DR0250 simple sugar transport system permease, ev=0.0, 69% identity YP_605155.1 PFAM: inner-membrane translocator: (7.6e-43); KEGG: ttj:TTHA1856 ABC transporter permease, ev=4e-97, 60% identity YP_605156.1 PFAM: regulatory protein, LysR: (5.1e-17) LysR, substrate-binding: (7e-38); KEGG: syf:Synpcc7942_2418 transcriptional regulator, ev=3e-40, 36% identity YP_605158.1 PFAM: Peptidoglycan-binding LysM: (8.2e-11); KEGG: dra:DR0910 cell wall protein, , ev=1e-130, 58% identity YP_605159.1 PFAM: ribosome-binding factor A: (9.5e-07); KEGG: dra:DR0901 ribosome-binding factor A, , ev=8e-34, 77% identity YP_605160.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase: (6.2e-27); PFAM: thioesterase superfamily: (3.8e-17); KEGG: dra:DR0902 hypothetical protein, ev=2e-47, 69% identity YP_605161.1 PFAM: NUDIX hydrolase: (1e-16); KEGG: dra:DR0876 hypothetical protein, ev=5e-73, 83% identity YP_605162.1 PFAM: peptidase M1, membrane alanine aminopeptidase: (5.2e-22); KEGG: dra:DR0875 zinc metalloprotease, , ev=1e-100, 53% identity YP_605163.1 PFAM: transposase, IS4: (6.3e-22); KEGG: dra:DRC0033 transposase, , ev=1e-94, 63% identity YP_605166.1 PFAM: transposase, IS4: (0.00042); KEGG: tth:TTC1433 hypothetical protein, ev=2e-29, 32% identity YP_605167.1 PFAM: phage integrase: (1.5e-28) phage integrase-like SAM-like: (6.7e-06); KEGG: nfa:pnf2210 recombinase, ev=8e-57, 42% identity YP_605168.1 PFAM: transposase Tn3: (0); KEGG: xcv:XCVb0015 Tn5045 transposase, ev=0.0, 49% identity YP_605170.1 PFAM: ATP-binding region, ATPase-like: (8.3e-24) histidine kinase, dimerisation and phosphoacceptor region: (6.2e-22); KEGG: dra:DR1556 two-component sensor, , ev=0.0, 67% identity YP_605171.1 KEGG: dra:DR1557 hypothetical protein, ev=2e-55, 39% identity YP_605172.1 PFAM: regulatory protein, LuxR: (1.4e-19) response regulator receiver: (1e-36) Sigma-70, region 4 type 2: (0.00066); KEGG: dra:DR1558 DNA-binding response regulator, ev=1e-92, 82% identity YP_605173.1 PFAM: Cupin 2, conserved barrel: (4.2e-19); KEGG: sco:SCO4483 hypothetical protein, ev=2e-11, 32% identity YP_605174.1 PFAM: Chlorite dismutase: (6.9e-82); KEGG: dra:DR1481 hypothetical protein, ev=1e-121, 84% identity YP_605175.1 PFAM: aldo/keto reductase: (3.5e-12); KEGG: hma:rrnAC2912 general stress protein 69, ev=6e-62, 39% identity YP_605176.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (4.3e-13); KEGG: dra:DR1695 lactoylglutathione lyase-related protein, ev=2e-46, 78% identity YP_605177.1 PFAM: protein of unknown function UPF0118: (6.7e-69); KEGG: dra:DR0252 hypothetical protein, ev=1e-151, 70% identity YP_605178.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_605179.1 KEGG: dra:DR2057 hypothetical protein, ev=4e-84, 81% identity YP_605180.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_605181.1 KEGG: dra:DR0714 hypothetical protein, ev=2e-43, 53% identity YP_605182.1 PFAM: Uracil-DNA glycosylase superfamily: (8.2e-20); KEGG: dra:DR0715 G/U mismatch-specific DNA glycosylase, ev=2e-71, 78% identity YP_605183.1 PFAM: oxidoreductase, molybdopterin binding: (2e-56); KEGG: dra:DR0716 hypothetical protein, ev=7e-96, 80% identity YP_605184.1 KEGG: ttj:TTHA1581 hypothetical protein, ev=3e-79, 51% identity YP_605185.1 PFAM: protein of unknown function DUF322: (9.3e-41); KEGG: dra:DR0389 hypothetical protein, ev=2e-41, 77% identity YP_605186.1 PFAM: Dak phosphatase: (2.7e-60); KEGG: dra:DR0390 hypothetical protein, ev=0.0, 83% identity YP_605187.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase: (1.6e-133); PFAM: cytoplasmic peptidoglycan synthetase-like: (0.0013) cytoplasmic peptidoglycan synthetases-like: (7.7e-07) Mur ligase, middle region: (2.9e-12); KEGG: dra:DR0768 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase, ev=1e-173, 73% identity YP_605188.1 KEGG: dra:DR0769 hypothetical protein, ev=2e-60, 52% identity YP_605189.1 TIGRFAM: type IV pilus assembly protein PilM: (5.9e-146); PFAM: cell division protein FtsA: (1.8e-05); KEGG: dra:DR0770 fimbrial assembly protein PilM, , ev=0.0, 84% identity YP_605190.1 PFAM: Fimbrial assembly: (0.0002); KEGG: dra:DR0771 type IV pilus assembly protein PilN, ev=2e-43, 42% identity YP_605191.1 KEGG: dra:DR0772 type IV pilus assembly protein PilO, ev=3e-36, 45% identity YP_605192.1 KEGG: dra:DR0773 hypothetical protein, ev=2e-28, 30% identity YP_605193.1 PFAM: type II and III secretion system protein: (1.1e-37) NolW-like: (2.6e-15); KEGG: dra:DR0774 general secretion pathway protein D, , ev=0.0, 54% identity YP_605194.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_605195.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_605196.1 PFAM: 3-dehydroquinate synthase: (1.3e-115); KEGG: dra:DR0777 3-dehydroquinate synthase, ev=1e-154, 77% identity YP_605197.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_605198.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_605199.1 forms a direct contact with the tRNA during translation YP_605200.1 PFAM: ABC transporter related: (2.2e-32); SMART: ATPase: (1.4e-13); KEGG: dra:DR2145 ABC transporter ATP-binding protein, ev=5e-85, 66% identity YP_605201.1 TIGRFAM: HAD-superfamily hydrolase subfamily IIB: (2.6e-15); PFAM: Haloacid dehalogenase-like hydrolase: (5.7e-05) sucrose-6F-phosphate phosphohydrolase: (0.00014) Haloacid dehalogenase-like hydrolase, type 3: (3.2e-18); KEGG: dra:DR2147 hypothetical protein, ev=2e-78, 66% identity YP_605202.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_605203.1 KEGG: lma:LmjF05.0240 viscerotropic leishmaniasis antigen, , ev=6e-08, 28% identity YP_605204.1 PFAM: GCN5-related N-acetyltransferase: (2.1e-09); KEGG: dra:DR0763 hypothetical protein, ev=5e-60, 70% identity YP_605205.1 TIGRFAM: lipoate-protein ligase B: (3.3e-25); PFAM: biotin/lipoate A/B protein ligase: (5.8e-14); KEGG: dra:DR0764 lipoate-protein ligase B, ev=9e-92, 71% identity YP_605206.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_605207.1 KEGG: dra:DR0767 short chain dehydrogenase, ev=6e-49, 60% identity YP_605208.1 TIGRFAM: GGDEF domain: (1.5e-12); PFAM: GGDEF: (1.5e-09); KEGG: sth:STH566 sensory box/GGDEF domain protein, ev=3e-14, 28% identity YP_605209.1 PFAM: protein of unknown function DUF427: (3.2e-52); KEGG: dra:DR0923 hypothetical protein, ev=2e-40, 80% identity YP_605210.1 PFAM: Fibronectin, type III: (0.0017) alpha amylase, catalytic region: (1.8e-72); SMART: Alpha amylase, catalytic subdomain: (2.7e-82); KEGG: gka:GK0707 alpha-amylase, ev=2e-68, 38% identity YP_605211.1 PFAM: protein of unknown function DUF47: (1.1e-16); KEGG: dra:DR0924 hypothetical protein, ev=2e-86, 76% identity YP_605212.1 PFAM: phosphate transporter: (1.6e-74); KEGG: dra:DR0925 low-affinity inorganic phosphate transporter , ev=1e-147, 78% identity YP_605213.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_605214.1 PFAM: AMP-dependent synthetase and ligase: (5.5e-117); KEGG: dra:DR0460 acetyl-CoA synthase, ev=0.0, 78% identity YP_605215.1 KEGG: dra:DR0459 hypothetical protein, ev=6e-96, 74% identity YP_605216.1 KEGG: dra:DR0458 hypothetical protein, ev=4e-82, 36% identity YP_605217.1 PFAM: Biopolymer transport protein ExbD/TolR: (3.5e-21); KEGG: dra:DR0457 biopolymer transport protein, , ev=2e-49, 72% identity YP_605218.1 PFAM: MotA/TolQ/ExbB proton channel: (2.7e-19); KEGG: dra:DR0456 biopolymer transport protein, , ev=4e-75, 70% identity YP_605219.1 KEGG: ecs:ECs0601 NfrB, ev=4e-58, 31% identity YP_605220.1 KEGG: mta:Moth_2139 beta-mannanase-like, ev=4e-20, 30% identity YP_605221.1 KEGG: rso:RS00391 hypothetical protein, ev=1e-55, 30% identity YP_605222.1 PFAM: aminotransferase, class I and II: (1.6e-45); KEGG: dra:DR2268 aminotransferase, ev=1e-176, 80% identity YP_605223.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_605224.1 TIGRFAM: SSS sodium solute transporter superfamily: (1.3e-74); PFAM: Na+/solute symporter: (1.3e-119); KEGG: dra:DR0477 sodium:solute symporter protein, ev=0.0, 81% identity YP_605225.1 PFAM: protein of unknown function DUF485: (1.3e-38); KEGG: dra:DR0476 hypothetical protein, ev=8e-32, 76% identity YP_605226.1 KEGG: gox:GOX0446 molybdenum cofactor biosynthesis protein A, ev=1e-101, 61% identity; TIGRFAM: Molybdenum cofactor biosynthesis protein A: (1.7e-165); PFAM: Radical SAM: (6.2e-41) molybdenum cofactor synthesis-like: (1.8e-39); SMART: Elongator protein 3/MiaB/NifB: (7.1e-13) YP_605227.1 PFAM: regulatory protein GntR, HTH: (2.5e-16) UbiC transcription regulator-associated: (3.2e-35); KEGG: dra:DR0265 histidine utilization repressor HutC, , ev=1e-115, 88% identity YP_605228.1 PFAM: regulatory protein, TetR: (2.8e-10); KEGG: dra:DR1402 transcriptional repressor, TetR family, ev=3e-97, 87% identity YP_605229.1 catalyzes the formation of 2-phospho-D-glyceroyl phosphate from ATP and 2-phospho-D-glycerate YP_605230.1 PFAM: FAD dependent oxidoreductase: (7.5e-06); KEGG: dra:DR0571 hypothetical protein, ev=1e-134, 64% identity YP_605231.1 TIGRFAM: SpoIID/LytB domain: (1.7e-98); PFAM: Stage II sporulation D: (7.8e-42); KEGG: dra:DR0572 sporulation protein SpoIID-related protein, ev=1e-122, 62% identity YP_605232.1 KEGG: dra:DR0573 hypothetical protein, ev=0.0, 57% identity YP_605233.1 KEGG: dra:DR0574 hypothetical protein, ev=7e-78, 48% identity YP_605234.1 PFAM: beta-lactamase: (2e-28); KEGG: dra:DR0760 hypothetical protein, ev=1e-106, 62% identity YP_605235.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_605236.1 PFAM: thioesterase superfamily: (4.5e-19); KEGG: dra:DRB0106 hypothetical protein, ev=4e-49, 77% identity YP_605237.1 PFAM: NrdI: (1.4e-09); KEGG: dra:DRB0107 ribonucleotide reductase, NrdI family, ev=2e-19, 56% identity YP_605238.1 KEGG: dra:DRB0108 ribonucleoside-diphosphate reductase alpha chain, ev=0.0, 67% identity; TIGRFAM: Ribonucleoside-diphosphate reductase, alpha subunit: (5.8e-186); PFAM: ribonucleotide reductase large subunit: (9.1e-104) Ribonucleotide reductase large subunit, N terminal: (2e-26) Ribonucleotide reductase-like: (9e-26) YP_605239.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_605240.1 KEGG: dra:DRB0110 thioredoxin-related protein, ev=1e-13, 48% identity YP_605241.1 PFAM: (Uracil-5)-methyltransferase: (0.00015); KEGG: dra:DR0238 hypothetical protein, ev=1e-92, 73% identity YP_605242.1 KEGG: dra:DR0239 hypothetical protein, ev=1e-16, 41% identity YP_605243.1 PFAM: amine oxidase: (2.2e-57) FAD dependent oxidoreductase: (2e-06); KEGG: dra:DR2015 oxidoreductase, FAD-binding, ev=1e-166, 72% identity YP_605244.1 KEGG: dra:DR2014 hypothetical protein, ev=2e-74, 70% identity YP_605245.1 PFAM: Rhomboid-like protein: (2.2e-24); KEGG: dra:DR1992 hypothetical protein, ev=2e-68, 63% identity YP_605246.1 KEGG: dra:DR2008 aspartate-semialdehyde dehydrogenase, ev=1e-147, 80% identity; TIGRFAM: Aspartate-semialdehyde dehydrogenase, USG-1 related: (4.4e-155); PFAM: Semialdehyde dehydrogenase, NAD - binding: (2.3e-45) Semialdehyde dehydrogenase, dimerisation region: (3.9e-64) YP_605247.1 KEGG: dra:DR2020 hypothetical protein, ev=3e-35, 65% identity YP_605248.1 PFAM: transposase, IS4: (5.4e-05); KEGG: lpp:lpp2895 hypothetical protein, ev=3e-42, 31% identity YP_605251.1 KEGG: mlo:mlr9023 transposase, ev=2e-11, 24% identity YP_605252.1 PFAM: protein of unknown function DUF205: (7.2e-69); KEGG: dra:DR2021 hypothetical protein, ev=2e-75, 73% identity YP_605253.1 TIGRFAM: GGDEF domain: (1.7e-05); PFAM: GGDEF: (4.2e-06) GAF: (4.2e-18); KEGG: dra:DRB0044 GGDEF family protein, ev=1e-42, 31% identity YP_605254.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase: (2.8e-11); KEGG: dra:DR2022 hypothetical protein, ev=3e-59, 77% identity YP_605255.1 PFAM: VanZ like protein: (1.5e-13); KEGG: dra:DR2023 hypothetical protein, ev=1e-37, 69% identity YP_605256.1 PFAM: ATPase associated with various cellular activities, AAA_3: (4.7e-77) ATPase associated with various cellular activities, AAA_5: (8e-13); KEGG: dra:DR0621 moxR protein, ev=1e-138, 81% identity YP_605257.1 PFAM: protein of unknown function DUF58: (4.3e-22) transglutaminase-like: (9.1e-27); KEGG: dra:DR0620 hypothetical protein, ev=0.0, 56% identity YP_605258.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_605260.1 TIGRFAM: Twin-arginine translocation pathway signal: (0.067); PFAM: peptidase M23B: (3.6e-30); KEGG: tte:TTE0841 membrane proteins related to metalloendopeptidase, ev=5e-14, 38% identity YP_605261.1 PFAM: Enoyl-CoA hydratase/isomerase: (5.2e-38); KEGG: dra:DR2510 enoyl-CoA hydratase, , ev=1e-115, 81% identity YP_605262.1 KEGG: dra:DR1172 hypothetical protein, ev=1e-08, 28% identity YP_605263.1 PFAM: major intrinsic protein: (5.3e-12); KEGG: bca:BCEA0165 MIP family channel protein, ev=8e-18, 30% identity YP_605264.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase: (1.5e-06); KEGG: dra:DR2184 hypothetical protein, ev=1e-173, 75% identity YP_605265.1 TIGRFAM: conserved hypothetical protein: (1.6e-35); PFAM: Allophanate hydrolase subunit 1: (1.7e-39); KEGG: bcl:ABC3773 hypothetical protein, ev=1e-34, 40% identity YP_605266.1 PFAM: Allophanate hydrolase subunit 2: (7.6e-60); KEGG: gka:GK1501 hypothetical protein, ev=2e-49, 38% identity YP_605267.1 PFAM: LamB/YcsF: (1.5e-96); KEGG: sth:STH2522 lactam utilization protein, ev=8e-55, 51% identity YP_605268.1 KEGG: dra:DR1006 dGTP triphosphohydrolase-related protein, ev=1e-131, 67% identity; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase: (1.6e-114); PFAM: metal-dependent phosphohydrolase, HD subdomain: (5.9e-19); SMART: Metal-dependent phosphohydrolase, HD region: (3.7e-16) YP_605269.1 PFAM: ABC-2 type transporter: (9.9e-07); KEGG: ape:APE2514 ABC-2 type transport system permease, ev=1e-16, 28% identity YP_605270.1 PFAM: ABC transporter related: (9e-53); SMART: ATPase: (2.1e-20); KEGG: ape:APE2516 ABC-2 type transport system ATP-binding protein, ev=9e-46, 43% identity YP_605271.1 PFAM: transposase, IS4: (0.00017); KEGG: tth:TTC1433 hypothetical protein, ev=5e-31, 33% identity YP_605272.1 PFAM: NUDIX hydrolase: (2.1e-26); KEGG: dra:DR1007 MutT/nudix family protein, ev=1e-59, 70% identity YP_605273.1 TIGRFAM: riboflavin biosynthesis protein RibF: (7.1e-81); PFAM: Riboflavin kinase / FAD synthetase: (9.8e-47); KEGG: dra:DR1008 riboflavin kinase / FMN adenylyltransferase, ev=1e-136, 79% identity YP_605274.1 PFAM: protein of unknown function DUF191: (6e-72); KEGG: dra:DR1011 hypothetical protein, ev=1e-113, 76% identity YP_605275.1 PFAM: ABC transporter related: (1.3e-48); SMART: ATPase: (1.2e-14); KEGG: dra:DR1012 ABC-2 type transport system ATP-binding protein, ev=1e-119, 72% identity YP_605276.1 KEGG: dra:DR1013 ABC-2 type transport system permease, ev=2e-93, 68% identity YP_605277.1 PFAM: transcription elongation factor GreA/GreB region: (2.2e-05); KEGG: dra:DR1970 transcription elongation factor, ev=9e-27, 41% identity YP_605279.1 KEGG: dra:DR0853 gliding motility protein, ev=5e-90, 84% identity YP_605280.1 PFAM: Roadblock/LC7: (4.9e-19); KEGG: dra:DR0854 hypothetical protein, ev=2e-66, 79% identity YP_605281.1 KEGG: dra:DR0855 hypothetical protein, ev=0.0, 59% identity YP_605282.1 KEGG: dra:DR0856 DNA polymerase III, epsilon subunit, , ev=4e-63, 68% identity; TIGRFAM: DNA polymerase III, epsilon subunit: (5e-07); PFAM: Exonuclease, RNase T and DNA polymerase III: (1.8e-39); SMART: Exonuclease: (7.9e-47) YP_605283.1 PFAM: UV-endonuclease UvdE: (4.4e-119); KEGG: dra:DR1819 UV damage endonuclease, , ev=1e-129, 76% identity YP_605284.1 KEGG: xcv:XCV4341 hypothetical protein, ev=2e-12, 59% identity YP_605285.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_605286.1 KEGG: dra:DR1816 hypothetical protein, ev=2e-71, 60% identity YP_605287.1 KEGG: dra:DR0887 hypothetical protein, ev=1e-35, 80% identity YP_605288.1 KEGG: dra:DR1994 hypothetical protein, ev=6e-59, 68% identity YP_605289.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_605290.1 PFAM: cytochrome c, class I: (3.8e-06); KEGG: dra:DRA0275 cytochrome c6, , ev=3e-42, 42% identity YP_605291.1 TIGRFAM: Twin-arginine translocation pathway signal: (0.0099); PFAM: amine oxidase: (5.6e-61) FAD dependent oxidoreductase: (0.0004); KEGG: dra:DRA0274 flavin monoamine oxidase-related protein, ev=0.0, 70% identity YP_605292.1 PFAM: NUDIX hydrolase: (1.1e-09); KEGG: dra:DR1025 MutT/NUDIX family protein, ev=7e-31, 71% identity YP_605293.1 KEGG: dra:DR0841 hypothetical protein, ev=2e-49, 56% identity YP_605294.1 PFAM: MazG nucleotide pyrophosphohydrolase: (7.3e-25); KEGG: dra:DR1022 hypothetical protein, ev=4e-45, 85% identity YP_605295.1 KEGG: dra:DR1021 hypothetical protein, ev=1e-58, 72% identity YP_605296.1 KEGG: dra:DR1020 cell division protein FtsH, ev=0.0, 77% identity; TIGRFAM: ATP-dependent metalloprotease FtsH: (4.3e-295); PFAM: peptidase M41: (8.5e-96) AAA ATPase, central region: (1e-92) peptidase M41, FtsH extracellular: (5.5e-29) ATPase associated with various cellular activities, AAA_5: (6.8e-05); SMART: ATPase: (4.8e-28) YP_605297.1 PFAM: MscS Mechanosensitive ion channel: (2.8e-52); KEGG: dra:DR1995 hypothetical protein, ev=1e-154, 65% identity YP_605298.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_605299.1 PFAM: protein of unknown function DUF88: (6.5e-80); KEGG: dra:DR1997m hypothetical protein, ev=7e-80, 85% identity YP_605300.1 PFAM: protein of unknown function DUF309: (1.7e-21); KEGG: dra:DR0943 hypothetical protein, ev=5e-34, 66% identity YP_605301.1 TIGRFAM: thioredoxin: (3.7e-58); PFAM: Thioredoxin domain: (1.7e-39); KEGG: dra:DR0944 thioredoxin, ev=2e-48, 84% identity YP_605302.1 PFAM: protein of unknown function DUF1234: (3.8e-85); KEGG: dra:DR0945 hypothetical protein, ev=9e-69, 69% identity YP_605303.1 is a component of the macrolide binding site in the peptidyl transferase center YP_605304.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_605305.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_605306.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_605307.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_605308.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_605309.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_605310.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_605311.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_605312.1 late assembly protein YP_605313.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_605314.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_605315.1 binds 5S rRNA along with protein L5 and L25 YP_605316.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_605317.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_605318.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_605319.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_605320.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_605321.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_605322.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_605323.1 one of the stabilizing components for the large ribosomal subunit YP_605324.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_605325.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_605326.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_605327.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_605328.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_605329.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_605330.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_605331.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_605332.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_605333.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_605334.1 KEGG: dra:DR0308 hypothetical protein, ev=3e-43, 71% identity YP_605335.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_605336.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_605337.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_605339.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_605340.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_605341.1 PFAM: transposase IS66: (0.00029); KEGG: dra:DRC0028 transposase, , ev=1e-172, 86% identity YP_605342.1 PFAM: NADPH-dependent FMN reductase: (0.00068) flavodoxin/nitric oxide synthase: (1.2e-09); KEGG: dra:DRA0214 trp repressor binding protein WrbA, , ev=1e-82, 76% identity YP_605343.1 PFAM: metallophosphoesterase: (3.6e-19); KEGG: dra:DR1260 hypothetical protein, ev=2e-93, 70% identity YP_605344.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_605346.1 PFAM: thioesterase superfamily: (1.9e-16); KEGG: bpm:BURPS1710b_1824 thioesterase family protein, ev=8e-47, 63% identity YP_605347.1 PFAM: Thiolase: (7e-144); KEGG: dra:DR1960 acetyl-CoA acetyltransferase, ev=1e-163, 73% identity YP_605348.1 PFAM: Ankyrin: (2.3e-07); KEGG: dra:DR1961 ankyrin-related protein, ev=3e-28, 52% identity YP_605349.1 KEGG: dra:DR1962 hypothetical protein, ev=2e-22, 42% identity YP_605350.1 TIGRFAM: Dihydrolipoamide acetyltransferase: (4e-305); PFAM: biotin/lipoyl attachment: (1.1e-27) catalytic domain of components of various dehydrogenase complexes: (4.1e-125) E3 binding: (1.9e-14); KEGG: dra:DR0256 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase), ev=0.0, 70% identity YP_605351.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_605352.1 PFAM: regulatory protein, LysR: (5e-20) LysR, substrate-binding: (4.6e-53); KEGG: dra:DR0615 transcriptional regulator, LysR family, ev=1e-129, 81% identity YP_605353.1 KEGG: dra:DR0494 DNA topology modulation protein FlaR-related protein, ev=2e-53, 61% identity YP_605354.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_605355.1 TIGRFAM: uracil-xanthine permease: (6.2e-124); PFAM: Xanthine/uracil/vitamin C permease: (2.6e-99); KEGG: dra:DR2280 uracil permease, ev=0.0, 81% identity YP_605356.1 PFAM: double-stranded RNA binding: (1.6e-12); KEGG: dra:DR2281 hypothetical protein, ev=3e-38, 57% identity YP_605357.1 TIGRFAM: HAD-superfamily hydrolase subfamily IA, variant 3: (7e-08); PFAM: Haloacid dehalogenase-like hydrolase: (6.3e-29); KEGG: gvi:glr2345 hypothetical protein, ev=4e-33, 40% identity YP_605358.1 PFAM: protein of unknown function UPF0102: (3.9e-27); KEGG: dra:DR2282 predicted endonuclease, ev=2e-38, 73% identity YP_605359.1 PFAM: glycosyl transferase, family 51: (5.7e-75) penicillin-binding protein, transpeptidase: (1.1e-44); KEGG: dra:DR0479 penicillin-binding protein 1, ev=0.0, 69% identity YP_605360.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_605361.1 PFAM: GCN5-related N-acetyltransferase: (6.6e-08); KEGG: lpp:plpp0112 hypothetical protein, ev=6e-12, 35% identity YP_605362.1 PFAM: protein of unknown function DUF72: (9.9e-86); KEGG: dra:DR0758 hypothetical protein, ev=1e-141, 87% identity YP_605363.1 PFAM: response regulator receiver: (2.3e-22); KEGG: dra:DR0731 response regulator, ev=5e-26, 55% identity YP_605364.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_605365.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_605366.1 KEGG: hypothetical protein, ev=2e-16, 40% identity YP_605367.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase: (5.4e-38); KEGG: dra:DR1815 hypothetical protein, ev=6e-57, 65% identity YP_605368.1 KEGG: dra:DR1814 hypothetical protein, ev=2e-30, 52% identity YP_605369.1 TIGRFAM: glycine cleavage system T protein: (7.4e-127); PFAM: glycine cleavage T protein (aminomethyl transferase): (3.9e-111); KEGG: dra:DR1812 aminomethyltransferase, , ev=1e-146, 76% identity YP_605370.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_605371.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_605373.1 PFAM: helix-turn-helix motif: (8e-16) protein of unknown function DUF955: (4.4e-16); KEGG: ppr:PBPRA1323 hypothetical protein, ev=5e-54, 35% identity YP_605374.1 KEGG: dra:DR0601 DNA primase, ev=0.0, 80% identity; TIGRFAM: DNA primase: (1.8e-124); PFAM: zinc finger, CHC2-type: (2.8e-40) TOPRIM: (1.6e-14) DNA primase catalytic core-like: (1.8e-67); SMART: Toprim subdomain: (3e-15) YP_605375.1 KEGG: dra:DR2601 hypothetical protein, ev=9e-94, 70% identity YP_605376.1 KEGG: dra:DR2528 hypothetical protein, ev=1e-103, 45% identity YP_605377.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_605378.1 KEGG: chy:CHY_2288 methionine aminopeptidase, type I, ev=2e-52, 41% identity; TIGRFAM: methionine aminopeptidase, type I: (7.5e-85); PFAM: peptidase M24: (1.8e-44) YP_605379.1 TIGRFAM: Phenylacetate-CoA oxygenase, PaaJ subunit: (3.9e-97); PFAM: protein of unknown function DUF59: (2.3e-33); KEGG: dra:DR2383 phenylacetic acid degradation protein PaaD, ev=3e-68, 77% identity YP_605380.1 TIGRFAM: Phenylacetate-CoA oxygenase, PaaI subunit: (3.2e-132); PFAM: phenylacetic acid catabolic: (5.3e-110); KEGG: dra:DR2384 phenylacetic acid degradation protein PaaC, ev=2e-98, 72% identity YP_605381.1 PFAM: phenylacetic acid degradation B: (8.2e-06); KEGG: dra:DR2385 phenylacetic acid degradation protein PaaB, , ev=2e-81, 75% identity YP_605382.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_605383.1 KEGG: dra:DRA0171 phosphomethylpyrimidine kinase, ev=7e-88, 71% identity; TIGRFAM: Phosphomethylpyrimidine kinase type-2: (1.9e-103); PFAM: Phosphomethylpyrimidine kinase type-1: (4.6e-120) YP_605384.1 PFAM: FAD dependent oxidoreductase: (2.6e-46); KEGG: ttj:TTHA0677 oxidoreductase, ev=6e-35, 36% identity YP_605385.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_605386.1 TIGRFAM: thiamine biosynthesis protein ThiS: (6.9e-21); PFAM: thiamineS: (2.5e-11); KEGG: dra:DRA0173 thiamin biosynthesis ThiS, ev=2e-20, 71% identity YP_605387.1 KEGG: dra:DRA0174 thiamine-phosphate pyrophosphorylase, ev=1e-82, 76% identity; TIGRFAM: thiamine-phosphate pyrophosphorylase: (1.1e-98); PFAM: thiamine monophosphate synthase: (3.1e-80) YP_605388.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_605389.1 PFAM: aldo/keto reductase: (2.3e-08); KEGG: dra:DR0249 oxidoreductase, , ev=1e-125, 70% identity YP_605390.1 KEGG: nfa:nfa22810 hypothetical protein, ev=1e-18, 32% identity YP_605391.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_605392.1 PFAM: major facilitator superfamily MFS_1: (2.4e-59); KEGG: dra:DR0258 multidrug-efflux transporter , ev=0.0, 76% identity YP_605393.1 PFAM: regulatory protein, MarR: (0.00013); KEGG: dra:DR0259 hypothetical protein, ev=6e-47, 64% identity YP_605394.1 PFAM: NUDIX hydrolase: (2.1e-27); KEGG: dra:DR0261 MutT/nudix family protein, ev=4e-36, 55% identity YP_605395.1 PFAM: major facilitator superfamily MFS_1: (2.9e-11); KEGG: dra:DR0260 CynX-related transport protein, , ev=1e-108, 64% identity YP_605396.1 TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily: (2e-187); PFAM: extracellular solute-binding protein, family 1: (6.6e-14); KEGG: dra:DR0262 thiamine transport system substrate-binding protein, ev=1e-153, 78% identity YP_605397.1 PFAM: binding-protein-dependent transport systems inner membrane component: (9.3e-05); KEGG: dra:DR2488 thiamine transport system permease, ev=0.0, 79% identity YP_605399.1 PFAM: SpoVT/AbrB-like: (1.2e-05) YP_605400.1 PFAM: PemK-like protein: (9.3e-26); KEGG: dra:DR0417 ppGpp-regulated growth inhibitor ChpA/MazF, , ev=2e-24, 50% identity YP_605401.1 PFAM: ABC transporter related: (1.5e-63); SMART: ATPase: (6.2e-19); KEGG: dra:DR0062 ABC transporter ATP-binding protein, ev=1e-110, 67% identity YP_605402.1 TIGRFAM: thiamine pyrophosphokinase: (2.2e-45); PFAM: Thiamin pyrophosphokinase, catalytic region: (4.4e-27); KEGG: dra:DR0552 hypothetical protein, ev=4e-79, 74% identity YP_605403.1 KEGG: dra:DR0553 hypothetical protein, ev=1e-162, 62% identity YP_605404.1 KEGG: dra:DR0554 hypothetical protein, ev=2e-63, 55% identity YP_605405.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_605406.1 PFAM: CoA-binding: (0.0017); KEGG: dra:DR0556 hypothetical protein, ev=2e-57, 71% identity YP_605407.1 PFAM: molybdopterin binding domain: (7.4e-53) MoeA-like, domain I and II: (2.2e-63) MoeA-like, domain IV: (3e-19); KEGG: dra:DR0076 molybdopterin biosynthesis MoeA, ev=1e-152, 71% identity YP_605408.1 PFAM: peptidylprolyl isomerase, FKBP-type: (0.00012); KEGG: dra:DR2464 peptidyl-prolyl cis-trans isomerase, FKBP-type, ev=3e-53, 64% identity YP_605409.1 PFAM: molybdopterin dehydrogenase, FAD-binding: (3.1e-72); KEGG: rso:RSc1467 probable carbon monoxide dehydrogenase medium subunit transmembrane protein, ev=3e-50, 47% identity YP_605410.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead: (1.2e-38) aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding: (1.8e-173); KEGG: rru:Rru_A0966 carbon-monoxide dehydrogenase, ev=0.0, 57% identity YP_605411.1 PFAM: ferredoxin: (8.4e-07) [2Fe-2S]-binding: (1.6e-42); KEGG: rso:RSc1469 dehydrogenase oxidoreductase, ev=3e-55, 63% identity YP_605412.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (6.5e-10); KEGG: dra:DR0950 NADH dehydrogenase II, ev=1e-180, 80% identity YP_605413.1 KEGG: dra:DR0150 hypothetical protein, ev=3e-55, 59% identity YP_605414.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_605415.1 PFAM: aminotransferase, class V: (1.4e-69); KEGG: dra:DR0215 aminotransferase, class V, ev=1e-166, 77% identity YP_605416.1 PFAM: PASTA: (8.2e-11); KEGG: dra:DR0350 hypothetical protein, ev=1e-164, 56% identity YP_605417.1 PFAM: branched-chain amino acid transport: (1e-20); KEGG: dra:DR0634 hypothetical protein, ev=2e-33, 68% identity YP_605418.1 PFAM: AzlC-like: (2.8e-52); KEGG: dra:DR0633 AzlC family protein, ev=2e-92, 76% identity YP_605419.1 PFAM: small multidrug resistance protein: (9.8e-07); KEGG: pae:PA1541 probable drug efflux transporter ev=1e-16, 37% identity YP_605420.1 PFAM: small multidrug resistance protein: (9.2e-16); KEGG: dvu:DVU3326 multidrug resistance protein, Smr family, ev=8e-18, 48% identity YP_605421.1 TIGRFAM: Amino acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine: (5.5e-33); PFAM: binding-protein-dependent transport systems inner membrane component: (9.9e-32); KEGG: dra:DR2277 polar amino acid transport system permease, ev=6e-99, 81% identity YP_605422.1 PFAM: extracellular solute-binding protein, family 3: (1e-77); SMART: Ionotropic glutamate receptor: (1.3e-09); KEGG: dra:DR2278 polar amino acid transport system substrate-binding protein, ev=1e-111, 79% identity YP_605423.1 KEGG: dra:DR0948 hypothetical protein, ev=7e-65, 76% identity YP_605424.1 KEGG: dra:DR2002 hypothetical protein, ev=8e-23, 48% identity YP_605425.1 KEGG: dra:DR2003 hypothetical protein, ev=6e-44, 56% identity YP_605426.1 PFAM: short-chain dehydrogenase/reductase SDR: (7.2e-09); KEGG: dra:DR0822 oxidoreductase, short-chain dehydrogenase/reductase family, ev=1e-106, 79% identity YP_605427.1 TIGRFAM: twin-arginine translocation protein, TatA/E family: (9.6e-21); PFAM: sec-independent translocation protein mttA/Hcf106: (5.9e-13); KEGG: dra:DR0805 sec-independent protein translocase, ev=9e-17, 53% identity YP_605428.1 TIGRFAM: Sec-independent protein translocase TatC: (4.5e-73); PFAM: Sec-independent periplasmic protein translocase: (3.5e-72); KEGG: dra:DR0806 Sec-independent protein translocase TatC, , ev=1e-100, 71% identity YP_605429.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_605430.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_605431.1 PFAM: major facilitator superfamily MFS_1: (8.7e-16); KEGG: ava:Ava_C0001 major facilitator superfamily MFS_1, ev=5e-37, 31% identity YP_605432.1 PFAM: ribonuclease H: (2.6e-42); KEGG: dra:DR0899 ribonuclease H, ev=2e-77, 76% identity YP_605433.1 KEGG: dra:DR0138 hypothetical protein, ev=2e-32, 46% identity YP_605434.1 PFAM: LmbE-like protein: (1.5e-36); KEGG: dra:DR1203 LmbE-related protein, ev=1e-114, 77% identity YP_605435.1 KEGG: dra:DR1590 hypothetical protein, ev=4e-64, 66% identity YP_605436.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_605437.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_605438.1 KEGG: dra:DR1597 glucose 6-phosphate dehydrogenase assembly protein OpcA, , ev=1e-124, 73% identity YP_605439.1 TIGRFAM: 6-phosphogluconolactonase: (1.9e-68); PFAM: glucosamine/galactosamine-6-phosphate isomerase: (8.6e-06); KEGG: gvi:glr3180 6-phosphogluconolactonase, ev=4e-44, 44% identity YP_605440.1 PFAM: peptidase M16-like: (1.2e-33); KEGG: dra:DR1598 protease, , ev=0.0, 71% identity YP_605441.1 PFAM: HEAT: (0.0045) 4Fe-4S ferredoxin, iron-sulfur binding: (0.00021) Domain of unknown function DUF1730: (6.9e-12); SMART: PBS lyase HEAT-like repeat: (3.8e-06); KEGG: tth:TTC0112 iron-sulfur cluster-binding protein, ev=5e-88, 51% identity YP_605442.1 KEGG: dra:DR1803 hypothetical protein, ev=1e-36, 60% identity YP_605443.1 PFAM: glutamine cyclotransferase: (2.2e-135); KEGG: dra:DR0112 glutamine cyclotransferase, ev=2e-98, 65% identity YP_605444.1 KEGG: dra:DR0109 hypothetical protein, ev=6e-43, 66% identity YP_605445.1 PFAM: protein of unknown function DUF34: (1.9e-87); KEGG: dra:DR0110 hypothetical protein, ev=1e-122, 79% identity YP_605446.1 PFAM: thymidylate kinase: (1.7e-66); KEGG: dra:DR0111 dTMP kinase, ev=5e-78, 73% identity YP_605448.1 PFAM: transcriptional regulator TrmB: (3.1e-27); KEGG: dra:DR0005 hypothetical protein, ev=1e-101, 84% identity YP_605449.1 PFAM: extracellular solute-binding protein, family 3: (4.7e-101); SMART: Ionotropic glutamate receptor: (2.4e-06); KEGG: dra:DR0564 polar amino acid transport system substrate-binding protein, ev=1e-91, 68% identity YP_605450.1 TIGRFAM: Amino acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine: (7.4e-41); PFAM: binding-protein-dependent transport systems inner membrane component: (1.1e-31); KEGG: dra:DR0565 polar amino acid transport system permease, ev=3e-92, 80% identity YP_605451.1 KEGG: dra:DR0594 glycogen synthase, ev=0.0, 76% identity; TIGRFAM: Glycogen/starch synthases, ADP-glucose type: (1.2e-172); PFAM: glycosyl transferase, group 1: (3e-08) Starch synthase catalytic region: (7.6e-82) YP_605452.1 PFAM: alpha/beta hydrolase fold: (9.2e-17); KEGG: dra:DR0593 beta-ketoadipate enol-lactone hydrolase, , ev=1e-73, 61% identity YP_605453.1 TIGRFAM: RNA methyltransferase TrmH, group 1: (2.6e-63); PFAM: tRNA/rRNA methyltransferase (SpoU): (9.4e-38); KEGG: dra:DR0576 RNA methyltransferase, , ev=1e-107, 82% identity YP_605455.1 PFAM: GAF: (1.1e-08) ATP-binding region, ATPase-like: (4e-20) histidine kinase, dimerisation and phosphoacceptor region: (1.4e-24); KEGG: dra:DR0577 sensor histidine kinase, ev=0.0, 75% identity YP_605456.1 protein associated with Co2+ and Mg2+ efflux YP_605457.1 PFAM: peptidase M20: (0.0013) peptidase M42: (5.3e-116); KEGG: dra:DR0229 endoglucanase, , ev=1e-153, 74% identity YP_605459.1 TIGRFAM: TIM-barrel protein, yjbN family: (5.6e-196); PFAM: dihydrouridine synthase, DuS: (1.7e-118); KEGG: dra:DR1698 tRNA-dihydrouridine synthase A, ev=1e-166, 85% identity YP_605460.1 KEGG: dra:DR0600 hypothetical protein, ev=2e-26, 75% identity YP_605461.1 TIGRFAM: conserved hypothetical protein: (2.3e-106); PFAM: Radical SAM: (6.5e-18); KEGG: dra:DR0064 hypothetical protein, ev=0.0, 82% identity YP_605462.1 KEGG: tth:TTC0629 HD-hydrolase domain, ev=8e-89, 39% identity; TIGRFAM: uncharacterized domain HDIG: (0.00035); PFAM: GAF: (9.5e-08) metal-dependent phosphohydrolase, HD subdomain: (3.9e-25) PAS fold-3: (1.3e-07); SMART: Metal-dependent phosphohydrolase, HD region: (3.1e-13) YP_605464.1 KEGG: dra:DR1374 DNA topoisomerase I, ev=0.0, 79% identity; TIGRFAM: DNA topoisomerase I: (0); PFAM: TOPRIM: (5.6e-39) DNA topoisomerase, type IA, central: (4.8e-183); SMART: DNA topoisomerase, type IA, domain 2: (1.8e-50) DNA topoisomerase, type IA, DNA-binding: (2.8e-119) Toprim subdomain: (2e-39) YP_605465.1 PFAM: protein of unknown function DUF218: (1.9e-39); KEGG: ttj:TTHA0565 hypothetical protein, ev=1e-26, 45% identity YP_605466.1 TIGRFAM: integral membrane protein MviN: (5e-165); PFAM: virulence factor MVIN-like: (2.4e-126); KEGG: dra:DR0498 virulence factor-related protein, ev=0.0, 74% identity YP_605467.1 KEGG: dra:DR0569 hypothetical protein, ev=2e-11, 72% identity YP_605468.1 KEGG: dra:DR0569 hypothetical protein, ev=5e-79, 56% identity YP_605469.1 PFAM: GTP-binding protein, HSR1-related: (6.3e-35); KEGG: dra:DR0139 GTP-binding protein HflX, ev=0.0, 83% identity YP_605470.1 PFAM: transposase, IS4: (4.7e-07); KEGG: lil:LA3155 transposase, ev=7e-15, 28% identity YP_605471.1 PFAM: glycoside hydrolase, family 1: (5.4e-05) NAD-dependent epimerase/dehydratase: (7.1e-15) 3-beta hydroxysteroid dehydrogenase/isomerase: (1.3e-05) dTDP-4-dehydrorhamnose reductase: (1.3e-63); KEGG: oih:OB1128 spore coat polysaccharide synthesis (dTDP-4-dehydrorhamnose reductase), ev=2e-42, 40% identity YP_605472.1 PFAM: diacylglycerol kinase, catalytic region: (5.5e-16); KEGG: dra:DR2234 hypothetical protein, ev=1e-108, 67% identity YP_605473.1 PFAM: PHP-like: (1e-29); SMART: Phosphoesterase PHP-like: (8.8e-10); KEGG: dra:DR2235 hypothetical protein, ev=1e-110, 78% identity YP_605474.1 PFAM: GCN5-related N-acetyltransferase: (1.7e-15); KEGG: nfa:nfa21400 acetyltransferase, ev=7e-22, 43% identity YP_605475.1 KEGG: bte:BTH_I2740 type I restriction-modification system endonuclease, ev=0.0, 84% identity; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family: (2.2e-229); PFAM: type III restriction enzyme, res subunit: (1.2e-10) protein of unknown function DUF450: (1.4e-76); SMART: DEAD/DEAH box helicase-like: (4.7e-09) YP_605476.1 PFAM: Death-on-curing protein: (0.00038); KEGG: eba:ebA3754 death-on-curing family protein, ev=1e-113, 63% identity YP_605477.1 KEGG: xfa:XF2739 type I restriction-modification system endonuclease, ev=3e-26, 64% identity YP_605478.1 PFAM: protein of unknown function DUF262: (6.9e-23); KEGG: tma:TM0991 hypothetical protein, ev=1e-172, 52% identity YP_605479.1 PFAM: restriction modification system DNA specificity domain: (7.8e-18); KEGG: mca:MCA0836 type I restriction-modification system, S subunit, EcoA family, ev=1e-143, 63% identity YP_605480.1 PFAM: N-6 DNA methylase: (2.7e-181); KEGG: bte:BTH_I2743 type I restriction system adenine methylase, ev=0.0, 88% identity YP_605482.1 PFAM: AFG1-like ATPase: (1.9e-110); KEGG: dra:DR0759 hypothetical protein, ev=1e-131, 68% identity YP_605483.1 PFAM: RNA-binding S4: (4.1e-08); KEGG: dra:DR0787 hypothetical protein, ev=1e-107, 83% identity YP_605484.1 KEGG: dra:DR0900 hypothetical protein, ev=1e-35, 54% identity YP_605485.1 TIGRFAM: RNA methyltransferase TrmH, group 3: (9.7e-63); PFAM: tRNA/rRNA methyltransferase (SpoU): (1e-58) RNA 2-O ribose methyltransferase, substrate binding: (6.5e-18); KEGG: dra:DR0748 RNA methyltransferase, TrmH family, ev=1e-104, 80% identity YP_605486.1 PFAM: Aldose 1-epimerase: (1.2e-31); KEGG: dra:DR0747 aldose epimerase family protein, ev=1e-120, 70% identity YP_605487.1 KEGG: dra:DR0746 hypothetical protein, ev=5e-20, 66% identity YP_605488.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap: (2e-08); SMART: PDZ/DHR/GLGF: (7.6e-09); KEGG: dra:DR0745 periplasmic serine protease, HtrA/DegQ/DegS family, ev=1e-107, 59% identity YP_605489.1 PFAM: protein of unknown function DUF589: (4.7e-89); KEGG: dra:DR0566 hypothetical protein, ev=3e-68, 78% identity YP_605490.1 PFAM: thymidylate synthase complementing protein ThyX: (3.7e-57); KEGG: ttj:TTHA1096 thymidylate synthase-complementing protein (Thy1), ev=3e-41, 48% identity YP_605491.1 PFAM: ABC transporter related: (3.8e-48); SMART: ATPase: (7.4e-12); KEGG: sme:SMc03120 ATP-binding ABC transporter protein, ev=6e-67, 53% identity YP_605492.1 PFAM: ABC transporter related: (3e-44); SMART: ATPase: (7.7e-14); KEGG: bms:BRA0955 branched-chain amino acid ABC transporter ATP-binding protein LivF, , ev=2e-71, 58% identity YP_605493.1 KEGG: eba:ebA3428 predicted LivK, ABC-type branched-chain amino acid transport systems, periplasmic component, ev=2e-87, 43% identity YP_605494.1 PFAM: inner-membrane translocator: (6.2e-28); KEGG: rpa:RPA2277 possible ABC transporter permease, ev=2e-91, 59% identity YP_605495.1 PFAM: inner-membrane translocator: (8.1e-27); KEGG: eba:ebA3425 possible ABC transporter permease precursor, ev=4e-69, 47% identity YP_605496.1 TIGRFAM: Ribonucleotide reductase regulator NrdR-like: (6.1e-50); PFAM: ATP-cone: (1.4e-26); KEGG: dra:DR0087 ATP-cone domain protein, ev=1e-68, 84% identity YP_605497.1 PFAM: short-chain dehydrogenase/reductase SDR: (1.4e-05); KEGG: dra:DR0088 oxidoreductase, short-chain dehydrogenase/reductase family, ev=3e-79, 64% identity YP_605499.1 PFAM: NUDIX hydrolase: (1.3e-28); KEGG: dra:DR0550 MutT/NUDIX family protein, ev=2e-94, 80% identity YP_605500.1 KEGG: dra:DR0549 replicative DNA helicase, ev=1e-124, 93% identity; TIGRFAM: Protein splicing (intein) site: (5.3e-07); PFAM: DnaB-like helicase-like: (2.1e-50); SMART: Hedgehog/intein hint domain-like: (1.6e-10) Hedgehog/intein hint-like: (1.5e-16) YP_605501.1 PFAM: methylation: (1.2e-08); KEGG: dra:DR0548 pilin, type IV, , ev=2e-21, 53% identity YP_605502.1 PFAM: O-antigen polymerase: (3.5e-06); KEGG: tth:TTC1837 hypothetical membrane spanning protein, ev=2e-11, 27% identity YP_605503.1 KEGG: dra:DR0097 hypothetical protein, ev=8e-59, 60% identity YP_605504.1 KEGG: dra:DR2527 hypothetical protein, ev=1e-54, 65% identity YP_605505.1 PFAM: Methyltransferase type 11: (2.5e-17) Methyltransferase type 12: (4.3e-16); KEGG: dra:DR2622 hypothetical protein, ev=1e-105, 72% identity YP_605506.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_605507.1 KEGG: dra:DR2207 hypothetical protein, ev=2e-16, 60% identity YP_605508.1 TIGRFAM: V-type ATPase, D subunit: (3.4e-39); PFAM: H+-transporting two-sector ATPase, D subunit: (4.6e-63); KEGG: dra:DR0702 v-type ATP synthase, D subunit, ev=5e-97, 85% identity YP_605509.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex YP_605510.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex YP_605511.1 PFAM: Vacuolar H+-transporting two-sector ATPase, F subunit: (1.1e-06); KEGG: dra:DR0699 v-type ATP synthase, F subunit, ev=7e-43, 81% identity YP_605512.1 PFAM: H+-transporting two-sector ATPase, C (AC39) subunit: (6.4e-18); KEGG: dra:DR0698 v-type ATP synthase, C subunit, ev=1e-140, 77% identity YP_605513.1 PFAM: H+-transporting two-sector ATPase, E subunit: (4.4e-11); KEGG: dra:DR0697 v-type ATP synthase, E subunit, ev=3e-67, 69% identity YP_605514.1 PFAM: H+-transporting two-sector ATPase, C subunit: (1.9e-05); KEGG: dra:DR0696 v-type ATP synthase, K subunit, ev=2e-31, 73% identity YP_605515.1 PFAM: V-type ATPase, 116 kDa subunit: (3.6e-12); KEGG: dra:DR0695 v-type ATP synthase, I subunit, ev=0.0, 72% identity YP_605516.1 KEGG: dra:DR0694 hypothetical protein, ev=9e-33, 71% identity YP_605517.1 TIGRFAM: ammonium transporter: (2.4e-165); PFAM: Rh-like protein/ammonium transporter: (1.1e-140); KEGG: dra:DR0693 ammonium transporter ev=0.0, 76% identity YP_605518.1 PFAM: nitrogen regulatory protein P-II: (3.6e-48); KEGG: dra:DR0692 nitrogen regulatory protein P-II, ev=1e-55, 88% identity YP_605519.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_605520.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase: (1.8e-144); KEGG: dra:DR1031 (S)-2-hydroxy-acid oxidase, ev=1e-118, 61% identity YP_605521.1 KEGG: dra:DR0690 type I topoisomerase, , ev=1e-144, 74% identity YP_605522.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_605523.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_605524.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_605525.1 PFAM: GCN5-related N-acetyltransferase: (1.4e-08); KEGG: dra:DR0682 hypothetical protein, ev=9e-59, 69% identity YP_605526.1 PFAM: GCN5-related N-acetyltransferase: (8.5e-13); KEGG: dra:DR0681 hypothetical protein, ev=4e-57, 68% identity YP_605527.1 PFAM: histidine triad (HIT) protein: (2.1e-06); KEGG: oih:OB1345 cell-cycle regulation histidine triad (HIT) protein, ev=5e-16, 40% identity YP_605528.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_605529.1 PFAM: GCN5-related N-acetyltransferase: (6.3e-22); KEGG: dra:DR0677 acetyltransferase, , ev=2e-36, 58% identity YP_605530.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_605531.1 KEGG: dra:DR0673 hypothetical protein, ev=6e-25, 42% identity YP_605532.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase: (0.00056) aminotransferase, class I and II: (1.4e-66); KEGG: dra:DR0671 aminotransferase, class I, ev=1e-134, 65% identity YP_605533.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_605534.1 PFAM: sodium:dicarboxylate symporter: (4.1e-189); KEGG: dra:DR0656 proton/sodium-glutamate symport protein, ev=0.0, 89% identity YP_605535.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_605536.1 PFAM: DSBA oxidoreductase: (1.3e-64); KEGG: dra:DR0659 FrnE protein, ev=4e-93, 68% identity YP_605537.1 PFAM: Carboxylesterase, type B: (8.4e-153); KEGG: dra:DR2626 carboxylesterase, type B, ev=1e-160, 55% identity YP_605538.1 KEGG: dra:DR0583 cell division protein FtsH, ev=0.0, 77% identity; TIGRFAM: ATP-dependent metalloprotease FtsH: (1.7e-300); PFAM: peptidase M41: (1.3e-100) AAA ATPase, central region: (8.3e-92) peptidase M41, FtsH extracellular: (6.3e-27) ATPase associated with various cellular activities, AAA_5: (6.8e-05); SMART: ATPase: (4.8e-28) YP_605539.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_605540.1 PFAM: GrpE protein: (3.1e-39); KEGG: dra:DR0128 grpE protein, ev=2e-64, 68% identity YP_605541.1 PFAM: heat shock protein DnaJ-like: (1.3e-40) chaperone DnaJ-like: (9.7e-46); KEGG: dra:DR0126 DnaJ protein, ev=1e-132, 79% identity YP_605543.1 PFAM: CBS: (1.2e-32); KEGG: gka:GK1090 hypothetical protein, ev=2e-21, 44% identity YP_605544.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin: (3.9e-53); KEGG: dra:DR1459 serine protease, subtilase family, ev=0.0, 68% identity YP_605545.1 KEGG: dra:DR1202 hypothetical protein, ev=6e-53, 46% identity YP_605546.1 KEGG: dra:DR1589 fructose-bisphosphate aldolase, ev=1e-152, 88% identity; TIGRFAM: ketose-bisphosphate aldolases: (5.7e-100) fructose-1,6-bisphosphate aldolase, class II: (6.8e-209); PFAM: ketose-bisphosphate aldolase, class-II: (1.9e-127) YP_605547.1 PFAM: aminotransferase, class I and II: (5.8e-18); KEGG: dra:DR1588 aminotransferase, class I, , ev=1e-171, 75% identity YP_605548.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_605549.1 KEGG: dra:DR1585 ribonuclease PH, ev=1e-107, 80% identity; TIGRFAM: ribonuclease PH: (8.2e-53); PFAM: 3' exoribonuclease: (6.4e-27) YP_605550.1 PFAM: DoxX: (1.4e-16); KEGG: pac:PPA0920 hypothetical protein, ev=9e-23, 44% identity YP_605551.1 KEGG: dra:DR0800 hypothetical protein, ev=2e-06, 59% identity YP_605552.1 PFAM: Methyltransferase type 11: (0.0012) Methyltransferase type 12: (1.1e-10); KEGG: dra:DR1676 hypothetical protein, ev=1e-129, 76% identity YP_605553.1 PFAM: methyltransferase: (1.5e-26); KEGG: dra:DR1680 tRNA (guanine-N7-)-methyltransferase, ev=1e-144, 74% identity YP_605554.1 PFAM: glucose-inhibited division protein A: (2.4e-08) FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (0.00043); KEGG: dra:DR1681 GidA-related protein, ev=1e-106, 78% identity YP_605555.1 KEGG: dra:DR0361 competence protein ComEC/Rec2-related protein, ev=1e-111, 75% identity YP_605556.1 KEGG: dra:DR0360 hypothetical protein, ev=6e-19, 53% identity YP_605557.1 PFAM: GCN5-related N-acetyltransferase: (1.6e-11); KEGG: dra:DR0604 acetyltransferase, , ev=5e-68, 70% identity YP_605558.1 PFAM: response regulator receiver: (3.9e-20); KEGG: hma:rrnAC0411 response regulator receiver, ev=2e-22, 49% identity YP_605559.1 PFAM: response regulator receiver: (1.8e-36) ATP-binding region, ATPase-like: (1.4e-38) histidine kinase A-like: (1.2e-11) PAS fold-3: (1.8e-24) PAS fold-4: (0.0019) PAS fold: (1.3e-11); SMART: PAS: (2.1e-07) PAC motif: (2.9e-09); KEGG: gvi:glr2749 two-component hybrid sensor and regulator, ev=0.0, 51% identity YP_605560.1 KEGG: dra:DR0366 hypothetical protein, ev=0.0, 88% identity; TIGRFAM: conserved hypothetical protein: (5.5e-128); PFAM: Radical SAM: (4.2e-17); SMART: Elongator protein 3/MiaB/NifB: (5.1e-07) YP_605562.1 PFAM: protein of unknown function DUF178: (1.1e-18); KEGG: dra:DR0370 hypothetical protein, ev=1e-130, 83% identity YP_605563.1 PFAM: DinB: (4.2e-06); KEGG: dra:DR0050 hypothetical protein, ev=3e-17, 37% identity YP_605564.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase: (7.9e-11); KEGG: dra:DR0428 hypothetical protein, ev=1e-37, 69% identity YP_605565.1 PFAM: cytochrome c, class I: (2.7e-11); KEGG: dra:DR0429 cytochrome-related protein, ev=1e-41, 40% identity YP_605566.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_605567.1 PFAM: glycoside hydrolase family 2, immunoglobulin-like beta-sandwich: (0.0013) glycoside hydrolase family 2, TIM barrel: (1.4e-06) glycoside hydrolase family 2, sugar binding: (2.2e-27); KEGG: nmu:Nmul_A1940 glycoside hydrolase family 2, sugar binding, ev=1e-161, 47% identity YP_605569.1 PFAM: Dynamin: (6.1e-40) GTP-binding protein, HSR1-related: (3.9e-14); KEGG: dra:DR1235 hypothetical protein, ev=0.0, 82% identity YP_605570.1 KEGG: dra:DR1234 hypothetical protein, ev=2e-18, 49% identity YP_605571.1 PFAM: transposase, IS4: (0.00017); KEGG: tth:TTC1433 hypothetical protein, ev=5e-31, 33% identity YP_605572.1 PFAM: methylation: (4.6e-07); KEGG: dra:DR1234 hypothetical protein, ev=6e-43, 52% identity YP_605573.1 PFAM: methylation: (2.8e-06); KEGG: dra:DR1233 pilin, type IV, , ev=1e-19, 34% identity YP_605574.1 PFAM: methylation: (7.3e-07); KEGG: dra:DR1232 pilin, type IV, , ev=5e-25, 43% identity YP_605575.1 KEGG: dra:DR1231 hypothetical protein, ev=1e-113, 37% identity YP_605576.1 KEGG: dra:DR1936 hypothetical protein, ev=3e-27, 75% identity YP_605577.1 PFAM: protein of unknown function DUF45: (3.3e-11); KEGG: dra:DR2490 hypothetical protein, ev=3e-33, 67% identity YP_605578.1 PFAM: protein of unknown function, zinc metallopeptidase : (6.1e-187); KEGG: dra:DR2596 hypothetical protein, ev=1e-118, 72% identity YP_605579.1 PFAM: acriflavin resistance protein: (2.1e-132); KEGG: dra:DR0740 drug transport protein, , ev=0.0, 75% identity YP_605580.1 PFAM: secretion protein HlyD: (2e-10); KEGG: dra:DR0739 hypothetical protein, ev=1e-105, 58% identity YP_605581.1 KEGG: dra:DR0738 hypothetical protein, ev=1e-128, 74% identity YP_605582.1 PFAM: outer membrane efflux protein: (4.6e-10); KEGG: ttj:TTHA1004 hypothetical protein, ev=2e-39, 33% identity YP_605583.1 PFAM: regulatory protein, TetR: (1.2e-17); KEGG: dra:DR0735 transcriptional regulator, TetR family, ev=1e-65, 62% identity YP_605584.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_605585.1 PFAM: extracellular solute-binding protein, family 5: (2.4e-64); KEGG: dra:DR0363 peptide ABC transporter periplasmic peptide-binding protein, , ev=0.0, 71% identity YP_605586.1 PFAM: binding-protein-dependent transport systems inner membrane component: (2e-51); KEGG: dra:DR0364 peptide ABC transporter permease, , ev=1e-143, 73% identity YP_605587.1 PFAM: binding-protein-dependent transport systems inner membrane component: (1.3e-45); KEGG: dra:DR0365 peptide ABC transporter permease, ev=1e-117, 61% identity YP_605588.1 PFAM: GCN5-related N-acetyltransferase: (9.6e-07); KEGG: dra:DR0653 hypothetical protein, ev=3e-37, 50% identity YP_605589.1 KEGG: dra:DR0359 hypothetical protein, ev=1e-23, 48% identity YP_605590.1 PFAM: glycine cleavage T protein (aminomethyl transferase): (4.1e-09); KEGG: dra:DR0358 hypothetical protein, ev=1e-112, 72% identity YP_605591.1 PFAM: glutamyl-tRNA reductase: (2.5e-66) Shikimate/quinate 5-dehydrogenase: (2.7e-49); KEGG: dra:DR2547 glutamyl-tRNA reductase, ev=1e-144, 77% identity YP_605592.1 TIGRFAM: siroheme synthase, N-terminal domain: (1.4e-19); KEGG: cvi:CV0813 uroporphyrin-III C-methyltransferase, ev=2e-23, 46% identity YP_605594.1 TIGRFAM: uroporphyrin-III C-methyltransferase: (9e-132); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase: (6.1e-80) Uroporphyrinogen III synthase HEM4: (1e-26); KEGG: dra:DRA0011 uroporphyrin-III synthase / uroporphyrin-III C-methyltransferase, ev=1e-147, 60% identity YP_605596.1 PFAM: peptidase S58, DmpA: (1.3e-10); KEGG: dra:DR0782 hypothetical protein, ev=1e-134, 82% identity YP_605597.1 PFAM: protein of unknown function DUF187: (4.7e-13); KEGG: dra:DR2412 hypothetical protein, ev=0.0, 60% identity YP_605598.1 KEGG: dra:DR2410 DNA polymerase III, tau/gamma subunit, ev=0.0, 68% identity; TIGRFAM: DNA polymerase III, subunits gamma and tau: (2.7e-132); PFAM: AAA ATPase, central region: (2.8e-11); SMART: ATPase: (1.6e-13) YP_605599.1 TIGRFAM: Competence-damaged protein: (1.5e-68); PFAM: molybdopterin binding domain: (1.1e-55) CinA-like: (5.7e-09); KEGG: dra:DR2338 cinA protein, ev=1e-168, 76% identity YP_605600.1 PFAM: 2',5' RNA ligase: (1.2e-09); KEGG: dra:DR2339 2'-5' RNA ligase, , ev=3e-72, 67% identity YP_605601.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_605602.1 PFAM: BioY protein: (1.4e-37); KEGG: ttj:TTHA0904 biotin biosynthesis protein BioY, ev=2e-42, 53% identity YP_605603.1 TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity YP_605604.1 PFAM: ferric-uptake regulator: (4e-23); KEGG: ttj:TTHA0344 ferric uptake regulatory protein, ev=2e-29, 50% identity YP_605605.1 KEGG: dra:DR2342 hypothetical protein, ev=5e-49, 50% identity YP_605606.1 PFAM: multiple antibiotic resistance (MarC)-related proteins: (5.4e-63); KEGG: dra:DR2343 hypothetical protein, ev=2e-81, 72% identity YP_605607.1 PFAM: HNH endonuclease: (5.4e-11); SMART: HNH nuclease: (1.3e-14); KEGG: dra:DR2409 hypothetical protein, ev=2e-80, 83% identity YP_605608.1 PFAM: metal-dependent phosphohydrolase, HD subdomain: (3e-08); KEGG: dra:DR2421 hypothetical protein, ev=6e-79, 80% identity YP_605609.1 KEGG: dra:DR2344 hypothetical protein, ev=1e-20, 41% identity YP_605610.1 PFAM: response regulator receiver: (1.1e-23); KEGG: dra:DR2420 response regulator, ev=2e-59, 76% identity YP_605611.1 PFAM: ATP-binding region, ATPase-like: (9.2e-42) histidine kinase A-like: (4.6e-11) PAS fold-3: (0.00049) PAS fold-4: (2.2e-13) PAS fold: (4.7e-16); SMART: PAS: (2.3e-08) PAC motif: (0.0032); KEGG: dra:DR2419 sensory box sensor histidine kinase, ev=0.0, 51% identity YP_605612.1 PFAM: response regulator receiver: (2.3e-33) transcriptional regulatory protein-like: (5e-23); KEGG: dra:DR2418 DNA-binding response regulator, ev=1e-111, 93% identity YP_605613.1 PFAM: beta-lactamase-like: (1.4e-21) RNA-metabolising metallo-beta-lactamase: (8.5e-07); KEGG: ttj:TTHA1140 metallo-beta-lactamase superfamily protein, ev=0.0, 58% identity YP_605614.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_605615.1 binds and unfolds substrates as part of the ClpXP protease YP_605616.1 KEGG: dra:DR1974 ATP-dependent protease LA, ev=0.0, 85% identity; TIGRFAM: ATP-dependent protease La: (0); PFAM: peptidase S16, lon-like: (2e-12) AAA ATPase, central region: (2.2e-44) ATPase associated with various cellular activities, AAA_5: (8.5e-07); SMART: ATPase: (2e-14) YP_605617.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_605618.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_605619.1 KEGG: dra:DR2608 hypothetical protein, ev=3e-51, 70% identity YP_605620.1 PFAM: ribonuclease BN: (2.6e-63); KEGG: dra:DR2609 BrkB protein, , ev=1e-128, 62% identity YP_605621.1 TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase: (1e-115); PFAM: histidine biosynthesis: (1.4e-96); KEGG: dra:DR2495 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, ev=1e-104, 82% identity YP_605622.1 PFAM: regulatory protein, MerR: (2.2e-07) transcription activator, effector binding: (4.1e-21); KEGG: nfa:nfa2920 transcriptional regulator, ev=4e-21, 30% identity YP_605623.1 PFAM: glycosyl transferase, group 1: (7.8e-30); KEGG: dra:DR0444 lipopolysaccharide biosynthesis protein, , ev=1e-160, 72% identity YP_605624.1 catalyzes the oxidation of malate to oxaloacetate YP_605625.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_605626.1 KEGG: dra:DR2500 hypothetical protein, ev=9e-52, 68% identity YP_605627.1 PFAM: thioesterase superfamily: (9.5e-22); KEGG: dra:DR0279 acyl-CoA thioester hydrolase, ev=5e-58, 74% identity YP_605628.1 PFAM: Extracellular ligand-binding receptor: (4.1e-05); KEGG: dra:DR0280 branched-chain amino acid transport system substrate-binding protein, ev=1e-146, 73% identity YP_605629.1 PFAM: inner-membrane translocator: (2.1e-41); KEGG: dra:DR0281 branched-chain amino acid transport system permease, ev=1e-131, 83% identity YP_605630.1 PFAM: inner-membrane translocator: (4.8e-37); KEGG: dra:DR0282 branched-chain amino acid transport system permease, ev=1e-127, 71% identity YP_605631.1 PFAM: ABC transporter related: (3.8e-49); SMART: ATPase: (1.9e-12); KEGG: dra:DR0283 branched-chain amino acid transport system ATP-binding protein, ev=1e-120, 81% identity YP_605632.1 PFAM: ABC transporter related: (2.8e-46); SMART: ATPase: (2.3e-09); KEGG: dra:DR0284 branched-chain amino acid transport system ATP-binding protein, ev=1e-105, 82% identity YP_605633.1 PFAM: small multidrug resistance protein: (2.2e-34); KEGG: ccr:CC3443 sugE protein, ev=4e-38, 71% identity YP_605634.1 PFAM: aldo/keto reductase: (3.7e-77); KEGG: dra:DR2261 aldo/keto reductase, ev=1e-132, 73% identity YP_605635.1 PFAM: regulatory protein, DeoR: (1.6e-38) iron dependent repressor: (0.0018) Helix-turn-helix, type 11: (0.00086); KEGG: dra:DRB0076 glycerol-3-phosphate regulon repressor, ev=4e-95, 69% identity YP_605636.1 TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase: (4.6e-148); PFAM: phosphocarrier HPr protein: (1.8e-09) PEP-utilizing enzyme: (2e-132) phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2: (1.2e-60) PEP-utilising enzyme, mobile region: (5.7e-24) PEP-utilising enzyme-like: (1.5e-23); KEGG: dra:DRB0075 PTS system, multiphosphoryl transfer protein, domains EI, HPr, and fructose, ev=0.0, 74% identity YP_605637.1 PFAM: PfkB: (1.1e-53); KEGG: dra:DRB0074 1-phosphofructokinase, ev=1e-118, 71% identity YP_605638.1 TIGRFAM: PTS system, fructose-specific, IIB component: (8.1e-56) Phosphotransferase system, fructose IIC component: (2.9e-130); PFAM: phosphotransferase system, EIIC: (1.5e-23) phosphotransferase system PTS, fructose-specific IIB subunit: (2e-58); KEGG: dra:DRB0073 PTS system, fructose-specific IIBC component, ev=0.0, 79% identity YP_605639.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_605640.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit: (6.4e-142); KEGG: dra:DR1215 acetyl-CoA carboxylase carboxyl transferase subunit beta, ev=1e-129, 81% identity YP_605641.1 KEGG: dra:DR1216 hypothetical protein, ev=2e-42, 57% identity YP_605642.1 PFAM: GAF: (2.8e-20) ATP-binding region, ATPase-like: (2.2e-41) histidine kinase A-like: (2.3e-11) PAS fold-4: (0.00011) PAS fold: (0.0014); SMART: PAS: (6.1e-11); KEGG: mlo:mll8067 two-component sensor histidine kinase, ev=5e-69, 36% identity YP_605643.1 KEGG: dra:DR0443 pyrimidine-nucleoside phosphorylase, ev=0.0, 81% identity; TIGRFAM: Pyrimidine-nucleoside phosphorylase: (3.6e-228); PFAM: glycosyl transferase, family 3: (1.6e-35) Pyrimidine nucleoside phosphorylase-like: (4.8e-24) YP_605644.1 PFAM: protein of unknown function DUF1452: (3.5e-16); KEGG: nwi:Nwi_1145 protein of unknown function DUF1452, ev=3e-17, 55% identity YP_605645.1 KEGG: dra:DRA0290 cell division protein FtsH, ev=0.0, 84% identity; TIGRFAM: ATP-dependent metalloprotease FtsH: (1.1e-297); PFAM: peptidase M41: (2e-90) AAA ATPase, central region: (3.9e-94) peptidase M41, FtsH extracellular: (3.2e-35) ATPase associated with various cellular activities, AAA_5: (0.00022); SMART: ATPase: (3.1e-27) YP_605646.1 PFAM: Tetratricopeptide TPR_4: (0.021) Tetratricopeptide TPR_2: (0.0045); SMART: Tetratricopeptide region: (0.18); KEGG: dra:DRA0288 hypothetical protein, ev=1e-142, 74% identity YP_605647.1 KEGG: dra:DR0328 hypothetical protein, ev=3e-46, 63% identity YP_605648.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap: (4e-08); SMART: PDZ/DHR/GLGF: (1.1e-09); KEGG: dra:DR0327 periplasmic serine protease, HtrA/DegQ/DegS family, ev=1e-103, 56% identity YP_605649.1 KEGG: dra:DR0326 hypothetical protein, ev=1e-40, 55% identity YP_605650.1 PFAM: GCN5-related N-acetyltransferase: (0.0014); KEGG: dra:DR0367 hypothetical protein, ev=9e-82, 61% identity YP_605651.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_605652.1 PFAM: extracellular solute-binding protein, family 3: (3.4e-88); SMART: Ionotropic glutamate receptor: (1.1e-06); KEGG: dra:DR2610 polar amino acid transport system substrate-binding protein, ev=1e-90, 67% identity YP_605653.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_605654.1 PFAM: transposase, IS4: (4.7e-07); KEGG: lil:LA3155 transposase, ev=7e-15, 28% identity YP_605655.1 KEGG: dra:DR2237 hypothetical protein, ev=1e-22, 68% identity YP_605656.1 PFAM: carbonic anhydrase: (9.6e-18); KEGG: dra:DR2238 carbonic anhydrase, ev=2e-91, 72% identity YP_605657.1 PFAM: protein of unknown function DUF28: (8.5e-134); KEGG: dra:DR2548 hypothetical protein, ev=1e-118, 88% identity YP_605658.1 PFAM: periplasmic binding protein: (1.2e-37); KEGG: gvi:gll0580 hemin-binding periplasmic protein, ev=5e-78, 53% identity YP_605659.1 PFAM: Antibiotic biosynthesis monooxygenase: (2.4e-22); KEGG: dra:DR0446 hypothetical protein, ev=1e-34, 64% identity YP_605660.1 PFAM: transposase, IS4: (4.7e-07); KEGG: lil:LA3155 transposase, ev=7e-15, 28% identity YP_605661.1 PFAM: Amidohydrolase 3: (2.8e-76); KEGG: dra:DR2540 hypothetical protein, ev=0.0, 72% identity YP_605662.1 PFAM: response regulator receiver: (3.2e-35) transcriptional regulatory protein-like: (1.4e-13); KEGG: dra:DR2556 response regulator, ev=1e-152, 77% identity YP_605663.1 KEGG: dra:DR1987 hypothetical protein, ev=1e-24, 50% identity YP_605664.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_605665.1 PFAM: regulatory protein, MerR: (1.3e-10); KEGG: dra:DR2306 transcriptional regulator, MerR family, ev=1e-57, 75% identity YP_605666.1 PFAM: major facilitator superfamily MFS_1: (2.1e-49); KEGG: dra:DR2307 multidrug-efflux transporter , ev=0.0, 80% identity YP_605667.1 KEGG: dra:DR0218 hypothetical protein, ev=4e-30, 55% identity YP_605668.1 PFAM: transposase, IS4: (0.00017); KEGG: tth:TTC1433 hypothetical protein, ev=5e-31, 33% identity YP_605669.1 PFAM: Rhodanese-like: (2.5e-28); KEGG: dra:DR0217 thiosulfate sulfurtransferase, ev=1e-146, 83% identity YP_605670.1 PFAM: Fe-S metabolism associated SufE: (3.1e-27); KEGG: dra:DR0216 hypothetical protein, ev=2e-62, 83% identity YP_605671.1 PFAM: transposase, IS4: (6.3e-22); KEGG: dra:DRC0033 transposase, , ev=1e-94, 63% identity YP_605672.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_605674.1 PFAM: Mg2+ transporter protein, CorA-like: (2.6e-05); KEGG: dra:DR2463 transport protein, , ev=1e-144, 83% identity YP_605675.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding: (5.7e-08); KEGG: dra:DR2330 ferredoxin, ev=1e-37, 87% identity YP_605676.1 KEGG: dra:DR2329 hypothetical protein, ev=8e-93, 69% identity YP_605677.1 PFAM: ATP-binding region, ATPase-like: (1.6e-35) histidine kinase, HAMP region: (2.6e-13) histidine kinase A-like: (1.1e-06); KEGG: dra:DR2328 sensor histidine kinase, ev=1e-132, 58% identity YP_605678.1 PFAM: response regulator receiver: (8.8e-30) transcriptional regulatory protein-like: (4.6e-17); KEGG: dra:DR2327 response regulator, ev=1e-103, 83% identity YP_605679.1 PFAM: ribosomal protein L21: (2.4e-36); KEGG: dra:DR0086 50S ribosomal protein L21, ev=2e-36, 71% identity YP_605680.1 involved in the peptidyltransferase reaction during translation YP_605681.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_605682.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type: (3.9e-38); KEGG: dra:DR2542 peptidyl-prolyl cis-trans isomerase, cyclophilin-type, ev=8e-78, 79% identity YP_605683.1 KEGG: dra:DR2543 cytidylate kinase, ev=1e-79, 76% identity; TIGRFAM: cytidylate kinase: (8.9e-44); PFAM: cytidylate kinase region: (1.6e-31) YP_605684.1 PFAM: phospholipid/glycerol acyltransferase: (1.6e-29); KEGG: dra:DR2587 hypothetical protein, ev=8e-39, 49% identity YP_605685.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin: (8.5e-63) protease-associated PA: (2e-23) protein of unknown function DUF1034: (0.0014); KEGG: cne:CNA01380 peptidase, , ev=4e-73, 30% identity YP_605686.1 PFAM: peptidase-like: (8.6e-06); KEGG: gsu:GSU1945 fibronectin type III domain protein, ev=1e-36, 41% identity YP_605687.1 PFAM: peptidase M16-like: (9.8e-34); KEGG: dra:DR2515 zinc protease, , ev=1e-148, 69% identity YP_605688.1 PFAM: peptidase M16-like: (9.2e-42); KEGG: dra:DR2516 hypothetical protein, ev=1e-110, 65% identity YP_605689.1 TIGRFAM: Pseudouridine synthase, RluD: (2.8e-60); PFAM: pseudouridine synthase: (6.5e-39); KEGG: dra:DR1684 pseudouridine synthase, , ev=3e-99, 64% identity YP_605690.1 PFAM: peptidase M23B: (1.9e-33); KEGG: dra:DR0598 hypothetical protein, ev=2e-63, 68% identity YP_605691.1 PFAM: Phosphoglycerate mutase: (1.1e-37); KEGG: dra:DR0602 phosphoglycerate mutase-related protein, ev=1e-70, 67% identity YP_605692.1 TIGRFAM: GGDEF domain: (1.9e-26); PFAM: GGDEF: (4.4e-29); KEGG: dra:DR0605 GGDEF family protein, ev=3e-89, 83% identity YP_605693.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_605694.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_605695.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM YP_605696.1 PFAM: Peptidoglycan-binding domain 1: (3.2e-17); KEGG: dra:DR2159 hypothetical protein, ev=2e-42, 43% identity YP_605697.1 PFAM: tRNA/rRNA methyltransferase (SpoU): (8.3e-39); KEGG: dra:DR2211 tRNA (guanosine-2'-O-)-methyltransferase, ev=1e-96, 80% identity YP_605698.1 PFAM: Integral membrane protein TerC: (8.9e-11); KEGG: tth:TTC0750 hypothetical membrane spanning protein, ev=7e-41, 40% identity YP_605699.1 PFAM: helix-turn-helix, AraC type: (2e-05) AraC-type transcriptional regulator-like: (2.1e-44); KEGG: bur:Bcep18194_C6605 transcriptional regulator, AraC family, ev=9e-81, 54% identity YP_605700.1 KEGG: bmb:BruAb2_0756 hypothetical protein, ev=1e-16, 53% identity YP_605701.1 PFAM: short-chain dehydrogenase/reductase SDR: (2.3e-46); KEGG: sru:SRU_1212 NAD dependent epimerase/dehydratase family, ev=1e-77, 67% identity YP_605702.1 PFAM: aldo/keto reductase: (1.2e-59); KEGG: bja:bll4597 aldo-keto reductase, ev=1e-113, 65% identity YP_605703.1 PFAM: Carboxylyase-related protein: (2.1e-162); KEGG: dra:DR0332 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, ev=0.0, 75% identity YP_605704.1 PFAM: peptidase M24: (9e-10); KEGG: dra:DR0478 peptidase-related protein, ev=1e-133, 75% identity YP_605705.1 TIGRFAM: UDP-glucose 4-epimerase: (1.3e-209); PFAM: NAD-dependent epimerase/dehydratase: (7.7e-77) 3-beta hydroxysteroid dehydrogenase/isomerase: (1.1e-09) polysaccharide biosynthesis protein CapD: (0.00025) dTDP-4-dehydrorhamnose reductase: (1.5e-07) Male sterility-like: (1.4e-06); KEGG: dra:DR2202 UDP-glucose 4-epimerase, ev=1e-155, 80% identity YP_605706.1 PFAM: regulatory protein, LacI: (1.4e-05) periplasmic binding protein/LacI transcriptional regulator: (3.1e-09); KEGG: dra:DR2501 transcriptional regulator, sugar-binding, , ev=1e-96, 59% identity YP_605707.1 PFAM: major facilitator superfamily MFS_1: (1.4e-20); KEGG: dra:DR2502 transport protein, , ev=1e-146, 71% identity YP_605708.1 PFAM: regulatory protein, MerR: (5.2e-07) Citrate synthase: (3.6e-14); KEGG: mlo:mlr3843 citrate synthase II, ev=9e-72, 43% identity YP_605709.1 PFAM: pyruvate carboxyltransferase: (2.7e-11); KEGG: cac:CAC0970 isopropylmalate synthase, ev=4e-71, 38% identity YP_605710.1 PFAM: protein of unknown function DUF344: (2.8e-108); KEGG: dra:DR0132 hypothetical protein, ev=1e-100, 67% identity YP_605711.2 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_605712.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_605713.1 TIGRFAM: ribosomal protein L28: (2e-24); KEGG: ttj:TTHA0042 50S ribosomal protein L28, ev=1e-14, 62% identity YP_605714.1 PFAM: Transglycosylase-associated protein: (6e-10); KEGG: dra:DR2389 transglycosylase associated protein, ev=4e-36, 82% identity YP_605715.1 TIGRFAM: threonine synthase: (1.8e-156); PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit: (8.2e-94); KEGG: tma:TM0546 threonine synthase, ev=1e-123, 63% identity YP_605716.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_605718.1 PFAM: MMPL: (1.2e-08); KEGG: dra:DR0108 hypothetical protein, ev=0.0, 70% identity YP_605719.1 PFAM: aminoglycoside phosphotransferase: (5.8e-50); KEGG: dra:DR0066 aminoglycoside 3'-phosphotransferase, ev=1e-104, 74% identity YP_605720.1 KEGG: dra:DR0067 hypothetical protein, ev=5e-81, 55% identity YP_605721.1 KEGG: dra:DR0068 hypothetical protein, ev=1e-33, 58% identity YP_605722.1 PFAM: CDP-alcohol phosphatidyltransferase: (0.00092); KEGG: ttj:TTHA0459 hypothetical protein, ev=3e-30, 40% identity YP_605723.1 KEGG: dra:DR0106 hypothetical protein, ev=1e-108, 84% identity YP_605724.1 PFAM: beta-lactamase-like: (1e-34); KEGG: dra:DR2557 hypothetical protein, ev=1e-86, 72% identity YP_605725.1 KEGG: dra:DR2332 DNA polymerase III subunit, , ev=1e-127, 73% identity YP_605726.1 PFAM: metallophosphoesterase: (8.7e-16); KEGG: dra:DR2331 hypothetical protein, ev=1e-101, 69% identity YP_605727.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase: (3.8e-12); KEGG: dra:DR2433 nitrilase-related protein, ev=1e-112, 70% identity YP_605728.1 PFAM: metalloenzyme: (7.2e-06); KEGG: dra:DR0122 hypothetical protein, ev=2e-97, 63% identity YP_605729.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI): (6.9e-40); KEGG: dra:DR0123 phosphoribosylanthranilate isomerase, ev=1e-67, 66% identity YP_605730.1 KEGG: dra:DR0124 hypothetical protein, ev=4e-25, 74% identity YP_605731.1 PFAM: regulatory protein, MarR: (0.0025) iron dependent repressor: (6.9e-17) FeoA: (4.4e-09); KEGG: dra:DR2539 iron dependent repressor, , ev=1e-92, 79% identity YP_605732.1 PFAM: sigma-70 region 2: (2.2e-20) sigma-70 region 4: (1.1e-16) Sigma-70, region 4 type 2: (7.5e-19); KEGG: sco:SCO3892 RNA polymerase sigma factor, ev=3e-23, 43% identity YP_605735.1 PFAM: transposase, IS891/IS1136/IS1341: (1.5e-86) transposase, IS605 OrfB: (1.7e-30); KEGG: dra:DR2324 transposase, , ev=6e-78, 42% identity YP_605736.1 PFAM: transposase IS200-like: (1.1e-27); KEGG: ctc:pE88_40 transposase-related protein, ev=2e-33, 53% identity YP_605737.1 KEGG: bba:Bd2777 predicted hydrolase of HD superfamily, ev=5e-23, 41% identity YP_605738.1 KEGG: bcl:ABC2538 hypothetical protein, ev=7e-06, 32% identity YP_605739.1 PFAM: transposase, IS4: (6.3e-22); KEGG: dra:DRC0033 transposase, , ev=1e-94, 63% identity YP_605740.1 PFAM: phage integrase: (7.6e-15) phage integrase-like SAM-like: (2.3e-08); KEGG: dra:DRB0104 integrase/recombinase XerD, , ev=1e-39, 36% identity YP_605742.1 KEGG: bpm:BURPS1710b_2504 hypothetical protein, ev=2e-52, 41% identity YP_605743.1 TIGRFAM: Twin-arginine translocation pathway signal: (0.00036); PFAM: protein of unknown function DUF1501: (1.9e-12); KEGG: cvi:CV3166 hypothetical protein, ev=4e-58, 37% identity YP_605746.1 TIGRFAM: transketolase: (0); PFAM: Transketolase-like: (7e-198) Transketolase, central region: (3.3e-65); KEGG: dra:DR2256 transketolase, ev=0.0, 81% identity YP_605747.1 Essential for recycling GMP and indirectly, cGMP YP_605748.1 KEGG: dra:DRA0141 hypothetical protein, ev=6e-36, 53% identity YP_605749.1 PFAM: regulatory proteins, AsnC/Lrp: (1.5e-18); KEGG: dra:DR2287 transcriptional regulator, AsnC family, ev=5e-38, 83% identity YP_605750.1 KEGG: tdn:Tmden_1976 transcriptional regulator, AsnC family, ev=5e-75, 41% identity YP_605751.1 PFAM: short-chain dehydrogenase/reductase SDR: (3.1e-35); KEGG: dra:DRA0364 oxidoreductase, short-chain dehydrogenase/reductase family, ev=1e-130, 74% identity YP_605753.1 PFAM: HhH-GPD: (4.4e-07); KEGG: dra:DR2438 endonuclease III, ev=1e-104, 77% identity YP_605754.1 TIGRFAM: methionyl-tRNA formyltransferase: (8.7e-81); PFAM: formyl transferase-like: (5.5e-46); KEGG: dra:DR2435 methionyl-tRNA formyltransferase, ev=1e-134, 76% identity YP_605755.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_605756.1 PFAM: TPR repeat: (9e-05) Tetratricopeptide TPR_2: (2.6e-07); SMART: Tetratricopeptide region: (0.0005); KEGG: dra:DR0121 hypothetical protein, ev=1e-134, 65% identity YP_605757.1 KEGG: dra:DR2541 hypothetical protein, ev=2e-48, 55% identity YP_605759.1 PFAM: Alcohol dehydrogenase, zinc-binding: (2.3e-28) Alcohol dehydrogenase GroES-like: (5.3e-36); KEGG: pst:PSPTO2676 glutathione-independent formaldehyde dehydrogenase, ev=1e-161, 70% identity YP_605760.1 PFAM: protein of unknown function DUF892: (9.4e-57); KEGG: mlo:mlr3134 hypothetical protein, ev=2e-32, 46% identity YP_605761.1 KEGG: mlo:mll6353 transposase, ev=9e-09, 44% identity YP_605762.1 KEGG: noc:Noc_1096 hypothetical protein, ev=5e-34, 70% identity YP_605763.1 KEGG: tth:TTC1433 hypothetical protein, ev=4e-20, 35% identity YP_605765.1 PFAM: major facilitator superfamily MFS_1: (3.8e-17); KEGG: tth:TTC0525 hypothetical protein, ev=6e-57, 42% identity YP_605766.1 PFAM: LmbE-like protein: (4.6e-36); KEGG: dra:DR2363a hypothetical protein, ev=1e-108, 77% identity YP_605767.1 PFAM: FAD dependent oxidoreductase: (3.7e-06); KEGG: dra:DR2250 methoxyneurosporene dehydrogenase, ev=0.0, 73% identity YP_605768.1 PFAM: glycosyl transferase, family 2: (2.4e-22); KEGG: dra:DR0089 hypothetical protein, ev=1e-122, 65% identity YP_605769.1 PFAM: phospholipid/glycerol acyltransferase: (3.4e-18); KEGG: dra:DR0090 hypothetical protein, ev=5e-67, 61% identity YP_605770.1 PFAM: protein of unknown function DUF422: (5.8e-63); KEGG: dra:DR0091 hypothetical protein, ev=1e-100, 63% identity YP_605771.1 PFAM: amine oxidase: (0.0016) FAD dependent oxidoreductase: (2.5e-05); KEGG: dra:DR0093 phytoene dehydrogenase, , ev=0.0, 84% identity YP_605772.1 KEGG: dra:DR2016 hypothetical protein, ev=4e-12, 55% identity YP_605773.1 KEGG: dra:DR2286 hypothetical protein, ev=1e-105, 46% identity YP_605774.1 PFAM: GCN5-related N-acetyltransferase: (4e-08); KEGG: dra:DRA0019 hypothetical protein, ev=1e-111, 63% identity YP_605775.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F: (8.8e-87); KEGG: dra:DRA0206 oligoendopeptidase F, , ev=0.0, 72% identity YP_605776.1 TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase: (4e-105); PFAM: flavoprotein: (1e-10) DNA/pantothenate metabolism flavoprotein-like: (1.3e-31); KEGG: dra:DR0579 DNA/pantothenate metabolism flavoprotein, ev=1e-159, 74% identity YP_605777.1 PFAM: arginine repressor: (1.9e-34); KEGG: dra:DR0742 arginine repressor/activator, ev=6e-62, 77% identity YP_605778.1 PFAM: ATP-binding region, ATPase-like: (1.4e-41) histidine kinase, HAMP region: (4.9e-18) histidine kinase A-like: (1.1e-23); KEGG: dra:DR0744 sensor histidine kinase, ev=1e-176, 62% identity YP_605779.1 PFAM: response regulator receiver: (7.1e-36) transcriptional regulatory protein-like: (2.2e-27); KEGG: dra:DR0743 response regulator, ev=1e-122, 100% identity YP_605780.1 KEGG: sil:SPOA0207 adenylate/guanylate cyclase, ev=3e-13, 36% identity YP_605781.1 KEGG: dra:DR0849 hypothetical protein, ev=2e-49, 68% identity YP_605782.1 KEGG: dra:DR0850 hypothetical protein, ev=5e-23, 67% identity YP_605783.1 TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, : (1.3e-157); PFAM: UbiA prenyltransferase: (2.3e-66); KEGG: dra:DR0851 4-hydroxybenzoate octaprenyltransferase, ev=1e-141, 82% identity YP_605784.1 TIGRFAM: Dihydrolipoamide dehydrogenase: (3.5e-224); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (4.7e-29) pyridine nucleotide-disulphide oxidoreductase dimerisation region: (2.7e-62); KEGG: dra:DR2370 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component, , ev=0.0, 82% identity YP_605785.1 KEGG: dra:DR0130 coproporphyrinogen III oxidase, , ev=1e-161, 73% identity; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase: (3.7e-55); PFAM: Radical SAM: (3.9e-26) HemN-like: (2.2e-12); SMART: Elongator protein 3/MiaB/NifB: (1.3e-45) YP_605786.1 KEGG: dra:DR2558 hypothetical protein, ev=7e-46, 69% identity YP_605787.1 PFAM: protein of unknown function DUF124: (8.9e-64); KEGG: dra:DR0368 hypothetical protein, ev=4e-92, 71% identity YP_605788.1 PFAM: protein of unknown function DUF405: (1.4e-38) protein of unknown function DUF418: (1.7e-49); KEGG: dra:DR2253 hypothetical protein, ev=1e-114, 55% identity YP_605789.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_605790.1 SMART: Helix-turn-helix, AraC type: (7.2e-16); KEGG: ccr:CC2573 transcriptional regulator, AraC family, ev=3e-15, 32% identity YP_605791.1 PFAM: major facilitator superfamily MFS_1: (1e-48); KEGG: lin:lin0830 similar to tetracycline resistance protein, ev=4e-83, 41% identity YP_605792.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase: (0.0048) HI0933-like protein: (0.0029); KEGG: dra:DR2623 thioredoxin reductase (NADPH), ev=1e-140, 76% identity YP_605793.1 PFAM: VanW: (1.6e-63); KEGG: dra:DR0009 hypothetical protein, ev=1e-160, 65% identity YP_605794.1 TIGRFAM: parB-like partition proteins: (6.6e-47); PFAM: ParB-like nuclease: (8.8e-32); KEGG: dra:DR0012 chromosome partitioning protein, ev=1e-118, 76% identity YP_605795.1 PFAM: Cobyrinic acid a,c-diamide synthase: (5.4e-52); KEGG: dra:DR0013 chromosome partitioning ATPase Soj, ev=1e-120, 87% identity YP_605796.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_605797.1 KEGG: dra:DR0015 hypothetical protein, ev=8e-40, 73% identity YP_605798.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_605799.1 PFAM: dehydrogenase, E1 component: (4.7e-84); KEGG: dra:DR0029 2-oxoisovalerate dehydrogenase alpha subunit, ev=1e-166, 75% identity YP_605800.1 PFAM: Transketolase, central region: (1.4e-85) Transketolase-like: (9.6e-47); KEGG: dra:DR0030 2-oxoisovalerate dehydrogenase beta subunit, ev=1e-155, 79% identity YP_605801.1 KEGG: dra:DR0031 hypothetical protein, ev=6e-19, 61% identity YP_605802.1 PFAM: biotin/lipoyl attachment: (4e-24) catalytic domain of components of various dehydrogenase complexes: (6.2e-128) E3 binding: (4.3e-18); KEGG: dra:DR0032 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase), ev=0.0, 69% identity YP_605803.1 KEGG: dra:DR2414 hypothetical protein, ev=2e-20, 38% identity YP_605804.1 PFAM: response regulator receiver: (5.5e-35) transcriptional regulatory protein-like: (1.1e-18); KEGG: dra:DR2415 DNA-binding response regulator, ev=1e-114, 95% identity YP_605805.1 PFAM: ATP-binding region, ATPase-like: (5.3e-39) histidine kinase, HAMP region: (5.3e-07); KEGG: dra:DR2416 sensor histidine kinase, ev=1e-157, 65% identity YP_605806.1 TIGRFAM: DNA processing protein DprA, : (8.4e-84); PFAM: SMF protein: (6.3e-70); KEGG: dra:DR0120 smf protein, ev=1e-142, 73% identity YP_001527646.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system YP_001527647.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: mmr:Mmar10_1752 prevent-host-death family protein YP_001527651.1 KEGG: dge:Dgeo_2720 transposase, IS4 YP_001527652.1 PFAM: transposase IS4 family protein; KEGG: dge:Dgeo_1090 transposase, IS4 YP_001527653.1 PFAM: transposase IS4 family protein; KEGG: dge:Dgeo_2720 transposase, IS4 YP_001527654.1 KEGG: dge:Dgeo_2762 transposase YP_001527656.1 KEGG: dge:Dgeo_2285 hypothetical protein YP_001527657.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: gka:GK0703 alpha-cyclodextrinase YP_001527658.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oih:OB3422 sugar binding-protein dependent transporter system permease YP_001527659.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lin:lin0218 similar to sugar ABC transporters, permease proteins YP_001527660.1 PFAM: extracellular solute-binding protein family 1; KEGG: gvi:glr3199 sugar binding protein YP_001527661.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: tth:TTC0455 transcriptional repressor YP_001527663.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_001527665.1 PFAM: ribonuclease H; KEGG: tth:TTC1191 ribonuclease H YP_001527666.1 PFAM: AAA-4 family protein YP_001527672.1 KEGG: ter:Tery_2554 superfamily I DNA and RNA helicases and helicase subunits-like YP_001527673.1 PFAM: transposase IS4 family protein; KEGG: dge:Dgeo_2720 transposase, IS4 YP_001527674.1 KEGG: dge:Dgeo_1092 hypothetical protein YP_001527675.1 KEGG: dge:Dgeo_1093 hypothetical protein YP_001527676.1 KEGG: dge:Dgeo_2796 hypothetical protein YP_001527677.1 PFAM: IS1 transposase; KEGG: dge:Dgeo_2533 IS1 transposase YP_001527679.1 KEGG: art:Arth_4271 hypothetical protein YP_001527681.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eba:p1B136 putative histone acetyltransferase-related protein YP_001527682.1 PFAM: Protein of unknown function DUF1778; KEGG: gvi:gsl1200 hypothetical protein YP_001527683.1 KEGG: dra:DRA0182 hypothetical protein YP_001527685.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: bam:Bamb_4989 serine/threonine protein kinase YP_001527686.1 KEGG: dge:Dgeo_2762 transposase YP_001527689.1 KEGG: ade:Adeh_3253 type IV secretory pathway VirB4 components-like YP_001527691.1 KEGG: bam:Bamb_2010 TrbL/VirB6 plasmid conjugal transfer protein YP_001527692.1 KEGG: mta:Moth_0365 TraG protein YP_001527694.1 KEGG: bba:Bd3830 hypothetical protein YP_001527697.1 KEGG: lma:LmjF35.0520 proteophosphoglycan ppg4 YP_001527700.1 PFAM: Lytic transglycosylase catalytic; KEGG: rde:RD1_2576 transglycosylase SLT domain protein YP_001527701.1 SMART: AAA ATPase; KEGG: cyb:CYB_2625 R3H domain protein YP_001527705.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: dge:Dgeo_0165 single-strand binding protein YP_001527707.1 KEGG: rno:679882 hypothetical protein LOC679882 YP_001527708.1 PFAM: UvrD/REP helicase; SMART: AAA ATPase; KEGG: ter:Tery_4233 UvrD/REP helicase YP_001527709.1 KEGG: lma:LmjF36.2440 hypothetical protein, conserved YP_001527710.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: dge:Dgeo_0165 single-strand binding protein YP_001527711.1 PFAM: acyltransferase 3; KEGG: rle:RL2546 putative transmembrane acyltransferase YP_001527715.1 PFAM: RES domain protein YP_001527716.1 KEGG: mva:Mvan_2314 translation initiation factor IF-2 YP_001527721.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: dra:DRB0030 chromosome partitioning protein, ParB family YP_001527722.1 TIGRFAM: prevent-host-death family protein; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dra:DRB0031 chromosome partitioning ATPase, putative, ParA family YP_001527723.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: bce:BC1596 transporter, drug/metabolite exporter family YP_001527724.1 KEGG: dge:Dgeo_0295 hypothetical protein YP_001527728.1 PFAM: IS1 transposase; KEGG: dge:Dgeo_2533 IS1 transposase YP_001527729.1 PFAM: transposase IS4 family protein; KEGG: dge:Dgeo_2720 transposase, IS4 YP_001527731.1 PFAM: transposase IS3/IS911 family protein; KEGG: dge:Dgeo_2803 transposase IS3/IS911 YP_001527733.1 TIGRFAM: parB-like partition protein; KEGG: dge:Dgeo_2333 ParB-like protein partition proteins YP_001527735.1 PFAM: ATPase associated with various cellular activities AAA_5 YP_001527737.1 KEGG: dge:Dgeo_2762 transposase YP_001527739.1 PFAM: Alkaline phosphatase; KEGG: dge:Dgeo_2364 alkaline phosphatase YP_001527740.1 KEGG: dge:Dgeo_2365 hypothetical protein YP_001527743.1 KEGG: rrs:RoseRS_0609 ApbE family lipoprotein YP_001527744.1 PFAM: Ferric reductase domain protein transmembrane component domain; KEGG: rrs:RoseRS_0608 hypothetical protein YP_001527745.1 PFAM: protein of unknown function DUF125 transmembrane; KEGG: bbt:BBta_3418 hypothetical protein YP_001527746.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ttj:TTHA1003 sensor histidine kinase YP_001527747.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ttj:TTHA1002 response regulator YP_001527748.1 KEGG: mkm:Mkms_1880 conserved hypothetical protein YP_001527749.1 PFAM: helix-hairpin-helix motif; KEGG: dra:DR0207 hypothetical protein YP_001527751.1 KEGG: dge:Dgeo_2762 transposase YP_001527756.1 KEGG: dge:Dgeo_2762 transposase YP_001527757.1 PFAM: helicase domain protein; KEGG: san:gbs1352 hypothetical protein YP_001527765.1 PFAM: PKD domain containing protein; KEGG: mhu:Mhun_2840 PKD YP_001527768.1 KEGG: gox:GOX2431 hypothetical protein YP_001527769.1 PFAM: GPW/gp25 family protein YP_001527773.1 KEGG: nar:Saro_2987 hypothetical protein YP_001527775.1 PFAM: peptidase M23B; KEGG: lic:LIC11568 membrane peptidase YP_001527782.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: dge:Dgeo_0928 transposase, IS605 OrfB YP_001527785.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: dge:Dgeo_2277 phage integrase YP_001527786.1 KEGG: dge:Dgeo_2274 hypothetical protein YP_001527793.1 KEGG: mmc:Mmcs_4669 AAA ATPase containing von Willebrand factor type A (vWA) domain-like protein YP_001527794.1 KEGG: dra:DR0178 transposase, putative YP_001527796.1 KEGG: cme:CMK009C hypothetical protein Pfam: HPC2 YP_001527797.1 KEGG: gme:Gmet_1188 peptidoglycan-binding domain 1 YP_001527802.1 TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; KEGG: dge:Dgeo_0003 DNA polymerase III, beta subunit YP_001527809.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sus:Acid_0016 cobyrinic acid a,c-diamide synthase YP_001527813.1 KEGG: dge:Dgeo_2762 transposase YP_001527814.1 SMART: DEAD-like helicases; KEGG: spj:MGAS2096_Spy1151 superfamily II DNA and RNA helicase YP_001527819.1 PFAM: helicase domain protein; KEGG: lma:LmjF27.0240 kinetoplast-associated protein-like protein YP_001527825.1 KEGG: dge:Dgeo_2762 transposase YP_001527826.1 KEGG: tth:TTC1741 single-strand DNA binding protein (SSB) YP_001527827.1 PFAM: transposase IS4 family protein; KEGG: dge:Dgeo_2763 transposase, IS4 YP_001527828.1 KEGG: dge:Dgeo_2497 hypothetical protein YP_001527829.1 PFAM: Bifunctional DNA primase/polymerase; KEGG: fra:Francci3_1201 conserved hypothetical protein 2SC10A7.05c YP_001527830.1 PFAM: General secretory system II protein E domain protein; KEGG: ttj:TTHA0364 type IV pilus assembly protein PilF YP_001527834.1 KEGG: xcv:XCV3536 transcriptional regulator, LuxR family YP_001527836.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: atc:AGR_L_1215 hypothetical protein YP_001527837.1 PFAM: IS1 transposase; KEGG: dge:Dgeo_2533 IS1 transposase YP_001527840.1 KEGG: sco:SCO0628 secreted protein YP_001527841.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL3845 putative transmembrane permease component of ABC transporter YP_001527842.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_1220 probable uspA protein YP_001527843.1 PFAM: extracellular solute-binding protein family 1; KEGG: bcl:ABC3585 sugar ABC transporter substrate-binding protein YP_001527844.1 KEGG: dge:Dgeo_1302 putative IS4 family transposase YP_001527845.1 PFAM: helix-turn-helix domain protein; N-6 DNA methylase; KEGG: mfa:Mfla_1177 transcriptional regulator, XRE family YP_001527846.1 PFAM: restriction modification system DNA specificity domain; KEGG: vei:Veis_1566 restriction modification system DNA specificity domain YP_001527847.1 TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: mfa:Mfla_1175 type I site-specific deoxyribonuclease, HsdR family YP_001527848.1 PFAM: protein of unknown function DUF45; KEGG: mfa:Mfla_1174 protein of unknown function DUF45 YP_001527849.1 PFAM: transposase IS4 family protein; KEGG: sru:SRU_2185 putative transposase YP_001527850.1 KEGG: dge:Dgeo_1356 hypothetical protein