-- dump date 20140619_065436 -- class Genbank::CDS -- table cds_note -- id note YP_002985642.1 KEGG: ypk:y4113 chromosomal replication initiation protein; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: replication initiation factor DnaA; ATPase AAA YP_002985643.1 binds the polymerase to DNA and acts as a sliding clamp YP_002985644.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002985645.1 negatively supercoils closed circular double-stranded DNA YP_002985646.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4437 MFS efflux transporter YP_002985647.1 SMART: HNH nuclease; KEGG: hso:HS_0453 hypothetical protein YP_002985648.1 KEGG: vsp:VS_1368 hypothetical protein YP_002985649.1 KEGG: ecm:EcSMS35_4824 hypothetical protein YP_002985650.1 predicted SAM-dependent methyltransferase YP_002985651.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: eca:ECA0055 oligopeptidase A YP_002985652.1 KEGG: eca:ECA0060 hypothetical protein YP_002985653.1 PFAM: protein of unknown function DUF519; KEGG: plu:plu0374 hypothetical protein YP_002985654.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002985655.1 KEGG: abu:Abu_1172 DNA helicase YP_002985656.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: kpe:KPK_0472 peptidase, S15 family YP_002985657.1 KEGG: avi:Avi_0040 hypothetical protein YP_002985658.1 PFAM: protein of unknown function DUF161; KEGG: ppu:PP_0642 hypothetical protein YP_002985659.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: reu:Reut_C6217 AsnC family transcriptional regulator YP_002985660.1 KEGG: pap:PSPA7_1546 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain protein; methylguanine DNA methyltransferase ribonuclease domain protein; SMART: helix-turn-helix- domain containing protein AraC type YP_002985661.1 PFAM: GCN5-related N-acetyltransferase; KEGG: spe:Spro_2129 GCN5-related N-acetyltransferase YP_002985662.1 KEGG: vei:Veis_0626 hypothetical protein YP_002985663.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: swp:swp_0839 site-specific DNA-methyltransferase YP_002985665.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002985666.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: kpe:KPK_4014 GntR family transcriptional regulator YP_002985667.1 TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: eca:ECA0070 hypothetical protein YP_002985668.1 PFAM: Luciferase-like monooxygenase; KEGG: eca:ECA0071 monooxygenase YP_002985669.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA0072 ABC transporter ATP-binding protein YP_002985670.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0073 ABC transporter permease YP_002985671.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0074 ABC transporter permease YP_002985672.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0075 ABC-type transporter substrate binding protein YP_002985673.1 KEGG: spc:Sputcn32_3988 cytoplasmic protein YP_002985674.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: psa:PST_4121 probable short-chain dehydrogenase YP_002985675.1 PFAM: aminotransferase class-III; KEGG: kpn:KPN_00577 hypothetical protein YP_002985676.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: rlt:Rleg2_3040 ABC transporter YP_002985677.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: smd:Smed_2371 binding-protein-dependent transport systems inner membrane component YP_002985678.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: rru:Rru_A3455 binding-protein dependent transport system inner membrane protein YP_002985679.1 PFAM: NMT1/THI5 like domain protein; KEGG: avi:Avi_3461 ABC transporter substrate-binding protein (nitrate/sulfonate/taurine/bicarbonate) YP_002985680.1 PFAM: Tetracycline transcriptional regulator YcdC domain protein; regulatory protein TetR; KEGG: pna:Pnap_4037 TetR family transcriptional regulator YP_002985681.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: dac:Daci_3066 AraC family transcriptional regulator YP_002985682.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: rpc:RPC_2485 lysine exporter protein LysE/YggA YP_002985683.1 PFAM: ferric reductase domain protein transmembrane component domain; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; FAD-binding 8 domain protein; KEGG: dar:Daro_2745 oxidoreductase FAD-binding region YP_002985685.1 glutamate synthase is composed of subunits alpha and beta; subunit beta is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the subunit alpha, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_002985686.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_002985687.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_002985688.1 KEGG: pna:Pnap_4022 amidase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein YP_002985689.1 PFAM: NIPSNAP family containing protein YP_002985690.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bsu:BSU06240 hypothetical protein YP_002985691.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_002985693.1 KEGG: eca:ECA4385 hypothetical protein YP_002985694.1 KEGG: pcr:Pcryo_1617 hypothetical protein YP_002985695.1 KEGG: mmw:Mmwyl1_3852 abortive infection protein YP_002985696.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: eca:ECA0078 2-hydroxyacid dehydrogenase YP_002985697.1 PFAM: protein of unknown function DUF1471; KEGG: plu:plu4502 hypothetical protein YP_002985698.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0081 hypothetical protein YP_002985699.1 KEGG: eca:ECA0082 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_002985700.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA0083 hypothetical protein YP_002985701.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002985702.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002985703.1 KEGG: par:Psyc_1209 hypothetical protein YP_002985704.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: avi:Avi_5760 ABC transporter nucleotide binding/ATPase protein (sugar) YP_002985705.1 PFAM: ROK family protein; KEGG: avi:Avi_5412 transcriptional regulator ROK family YP_002985706.1 PFAM: ROK family protein; KEGG: avi:Avi_5514 transcriptional regulator ROK family YP_002985707.1 KEGG: avi:Avi_5513 hypothetical protein YP_002985708.1 PFAM: extracellular solute-binding protein family 1; KEGG: bra:BRADO4396 sugar ABC transporter periplasmic protein YP_002985709.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: rle:pRL120557 transmembrane permease transporter component YP_002985710.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: xca:xccb100_1976 permease of a sugar import ABC transporter YP_002985711.1 KEGG: eca:ECA0086 hypothetical protein YP_002985712.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0091 methyl-accepting chemotaxis protein YP_002985713.1 PFAM: manganese and iron superoxide dismutase; KEGG: ent:Ent638_4063 superoxide dismutase YP_002985714.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002985715.1 PFAM: aldehyde dehydrogenase; KEGG: eca:ECA0094 aldehyde dehydrogenase B YP_002985716.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: spe:Spro_0094 AraC family transcriptional regulator YP_002985717.1 PFAM: isochorismatase hydrolase; KEGG: spe:Spro_0095 isochorismatase hydrolase YP_002985718.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: eca:ECA0096 xylulose kinase YP_002985719.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002985720.1 periplasmic substrate-binding component of the ATP-dependent xylose transporter; high affinity YP_002985721.1 with XylFH is part of the high affinity xylose ABC transporter YP_002985722.1 PFAM: inner-membrane translocator; KEGG: eca:ECA0100 xylose transporter permease YP_002985723.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA0101 xylose operon regulatory protein YP_002985724.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA0102 hypothetical protein YP_002985725.1 PFAM: protein of unknown function DUF156; KEGG: aha:AHA_0625 hypothetical protein YP_002985726.1 PFAM: high-affinity nickel-transporter; KEGG: pmy:Pmen_2243 high-affinity nickel-transporter YP_002985727.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_002985728.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: atc:AGR_C_466 hypothetical protein YP_002985729.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ara:Arad_4435 transporter YP_002985730.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu0753 hypothetical protein YP_002985733.1 PFAM: multi antimicrobial extrusion protein MatE; KEGG: plu:plu0761 hypothetical protein YP_002985734.1 KEGG: pfl:PFL_0267 hypothetical protein YP_002985735.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pde:Pden_1138 helix-turn-helix-domain containing protein, AraC type YP_002985736.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cps:CPS_2119 ABC transporter ATP-binding protein YP_002985737.1 PFAM: protein of unknown function DUF214; KEGG: cps:CPS_2120 ABC transporter permease YP_002985738.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; ATPase AAA; KEGG: cps:CPS_2121 sigma-54 dependent DNA-binding response regulator YP_002985739.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: cps:CPS_2122 sensor histidine kinase YP_002985740.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: cbs:COXBURSA331_A0314 phosphopantetheinyl transferase YP_002985741.1 KEGG: neu:NE1226 hypothetical protein YP_002985742.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu0753 hypothetical protein YP_002985744.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: plu:plu0762 hypothetical protein YP_002985745.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu0757 hypothetical protein YP_002985747.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: plu:plu0762 hypothetical protein YP_002985748.1 KEGG: mes:Meso_1038 methylmalonyl-CoA epimerase YP_002985749.1 PFAM: AMP-dependent synthetase and ligase; KEGG: baa:BA_1915 AMP-binding enzyme YP_002985750.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bsu:BSU38500 D-alanine--D-alanyl carrier protein ligase YP_002985752.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mlo:mll6742 long chain acyl-CoA synthetase YP_002985753.1 KEGG: plu:plu0764 hypothetical protein YP_002985754.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mpo:Mpop_3620 Orn/DAP/Arg decarboxylase 2 YP_002985756.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002985757.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002985758.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: ppr:PBPRB0274 phosphotransferase system mannitol/fructose-specific IIA component YP_002985759.1 PFAM: sugar-specific permease SgaT/UlaA; phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: ppr:PBPRB0273 ascorbate-specific PTS system enzyme IIC/IIB YP_002985760.1 KEGG: ppr:PBPRB0271 L-ascorbate 6-phosphate lactonase YP_002985761.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; KEGG: ppr:PBPRB0270 hypothetical protein YP_002985762.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_002985763.1 negative regulator of ulaG and ulaABCDEF YP_002985764.1 KEGG: swd:Swoo_4575 amino acid adenylation YP_002985765.1 KEGG: pfo:Pfl01_1382 hypothetical protein YP_002985766.1 PFAM: glycosyl transferase family 2; KEGG: sea:SeAg_B4458 bactoprenol glucosyl transferase YP_002985767.1 PFAM: GtrA family protein; KEGG: sfv:SFV_0258 bactoprenol-linked glucose translocase YP_002985768.1 PFAM: Autoinducer-binding domain protein; regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: eca:ECA1561 quorum-sensing transcriptional regulator YP_002985769.1 KEGG: shm:Shewmr7_1780 hypothetical protein YP_002985770.1 PFAM: aminoglycoside phosphotransferase; KEGG: mxa:MXAN_2524 homoserine kinase YP_002985772.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: yps:YPTB0040 hypothetical protein YP_002985773.1 KEGG: kpe:KPK_4062 hypothetical protein YP_002985774.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0131 LysR family transcriptional regulator YP_002985775.1 PFAM: peptidase M19 renal dipeptidase; KEGG: atc:AGR_C_4575 membrane dipeptidase homolog YP_002985776.1 PFAM: extracellular solute-binding protein family 5; KEGG: oan:Oant_3741 extracellular solute-binding protein family 5 YP_002985777.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: oan:Oant_3740 binding-protein-dependent transport systems inner membrane component YP_002985778.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: oan:Oant_3739 binding-protein-dependent transport systems inner membrane component YP_002985779.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: atc:AGR_C_4569 dipeptide transporter DppD homolog YP_002985780.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: oan:Oant_3737 ABC transporter YP_002985781.1 PFAM: beta-lactamase; KEGG: spe:Spro_2075 beta-lactamase YP_002985782.1 PFAM: peptidase T2 asparaginase 2; KEGG: eca:ECA0132 L-asparaginase YP_002985783.1 PFAM: peptidase M55 D-aminopeptidase; KEGG: eca:ECA0133 hypothetical protein YP_002985784.1 PFAM: peptidase S58 DmpA; KEGG: eca:ECA0134 peptidase YP_002985785.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0135 ABC transporter permease YP_002985786.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0136 ABC transporter permease YP_002985787.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0137 ABC transporter periplasmic protein YP_002985788.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: eca:ECA0138 ABC transporter ATP-binding protein YP_002985789.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0139 mandelate racemase / muconate lactonizing enzyme family protein YP_002985790.1 PFAM: protein of unknown function DUF1611; KEGG: ppr:PBPRA1897 hypothetical protein YP_002985791.1 KEGG: eca:ECA3001 hypothetical protein YP_002985792.1 PFAM: protein of unknown function DUF202; KEGG: eca:ECA3000 hypothetical protein YP_002985793.1 KEGG: eca:ECA0140 ribonuclease PH; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2 YP_002985794.1 KEGG: esa:ESA_04090 orotate phosphoribosyltransferase; TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_002985795.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002985796.1 TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; KEGG: ent:Ent638_0099 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002985797.1 KEGG: eca:ECA0144 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein YP_002985798.1 KEGG: swi:Swit_3729 hypothetical protein YP_002985799.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002985800.1 required for 70S ribosome assembly YP_002985801.1 TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: yen:YE0065 50S ribosomal protein L33 YP_002985802.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002985803.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002985804.1 PFAM: glycosyl transferase family 2; KEGG: yps:YPTB0051 lipopolysaccharide core biosynthesis glycosyl transferase YP_002985805.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002985806.1 PFAM: glycosyl transferase group 1; KEGG: plu:plu4862 WalR protein YP_002985807.1 PFAM: glycosyl transferase family 9; KEGG: bma:BMA1910 heptosyltransferase family protein YP_002985808.1 PFAM: O-antigen polymerase; KEGG: hch:HCH_01051 O-antigen polymerase YP_002985809.1 PFAM: glycosyl transferase group 1; KEGG: eta:ETA_00760 glycosyl transferase, group 1 YP_002985810.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: dar:Daro_0152 lipopolysaccharide heptosyltransferase III YP_002985811.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: eca:ECA0163 ADP-heptose:LPS heptosyl transferase I YP_002985812.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_002985813.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002985814.1 KEGG: spe:Spro_4824 2-amino-3-ketobutyrate coenzyme A ligase; TIGRFAM: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: aminotransferase class I and II; aminotransferase class-III YP_002985815.1 TIGRFAM: L-threonine 3-dehydrogenase; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: pmr:PMI3178 L-threonine 3-dehydrogenase YP_002985816.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: eca:ECA0169 hypothetical protein YP_002985817.1 PFAM: peptidase M23; KEGG: eca:ECA0170 hypothetical protein YP_002985818.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: eca:ECA0171 rhodanese-related sulfurtransferase YP_002985819.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002985820.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002985821.1 catalyzes the O-acetylation of serine YP_002985822.1 PFAM: antimicrobial peptide resistance and lipid A acylation PagP; KEGG: eca:ECA0175 palmitoyl transferase for lipid A YP_002985823.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA0179 hypothetical protein YP_002985824.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0180 transcriptional activator protein YP_002985825.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002985826.1 PFAM: dienelactone hydrolase; KEGG: spe:Spro_0243 carboxymethylenebutenolidase YP_002985827.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002985828.1 KEGG: eca:ECA0186 hypothetical protein YP_002985829.1 KEGG: rpa:RPA2267 hypothetical protein YP_002985830.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002985831.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0189 mandelate racemase / muconate lactonizing enzyme YP_002985832.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0190 GntR family transcriptional regulator YP_002985833.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002985834.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002985835.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002985836.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002985837.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: eca:ECA4216 peptidyl-prolyl cis-trans isomerase C YP_002985838.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_002985839.1 PFAM: glycoside hydrolase family 28; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: yen:YE0164 exo-poly-alpha-D-galacturonosidase precursor YP_002985840.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_002985841.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_002985842.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: spe:Spro_0159 thioredoxin YP_002985843.1 KEGG: cko:CKO_00124 transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; ribonuclease B OB region domain; Rho termination factor domain protein; Rho termination factor RNA-binding; SMART: Cold shock protein; ATPase AAA YP_002985844.1 KEGG: yen:YE0171 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase YP_002985845.1 TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: yps:YPTB0171 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002985846.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4205 TDP-fucosamine acetyltransferase YP_002985847.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002985848.1 PFAM: polysaccharide biosynthesis protein; KEGG: eca:ECA4203 entero common antigen biosynthesis protein YP_002985849.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_002985850.1 enterobacterial common antigen polymerase YP_002985851.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: kpn:KPN_04295 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002985852.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_002985853.1 KEGG: aha:AHA_0731 steroid delta-isomerase domain-containing protein YP_002985854.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002985855.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4196 acetyltransferase YP_002985856.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4195 amino-acid ABC transporter binding protein YP_002985857.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4194 amino-acid ABC transporter permease YP_002985858.1 PFAM: ABC transporter; SMC domain protein; SMART: ATPase AAA; KEGG: eca:ECA4193 amino-acid ABC transporter ATP-binding protein YP_002985859.1 KEGG: eca:ECA4192 peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_002985860.1 NAD-binding YP_002985861.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_002985862.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: stm:STM4482 L-idonate transport protein YP_002985863.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: see:SNSL254_A4829 HTH-type transcriptional regulator IdnR YP_002985864.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; hypothetical protein; KEGG: eca:ECA4191 protoheme IX biogenesis protein YP_002985865.1 PFAM: protein of unknown function DUF513 hemX; KEGG: eca:ECA4190 uroporphyrinogen III C-methyltransferase YP_002985866.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002985867.1 KEGG: spe:Spro_0178 porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: porphobilinogen deaminase YP_002985868.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002985869.1 TIGRFAM: iron donor protein CyaY; PFAM: Frataxin family protein; KEGG: spe:Spro_0180 frataxin-like protein YP_002985870.1 KEGG: ses:SARI_03711 hypothetical protein YP_002985871.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002985872.1 PFAM: protein of unknown function DUF484; KEGG: eca:ECA4182 hypothetical protein YP_002985873.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002985874.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase; KEGG: eca:ECA4180 flavin mononucleotide phosphatase YP_002985875.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002985876.1 responsible for the influx of magnesium ions YP_002985877.1 TIGRFAM: membrane protein AbrB duplication; PFAM: ammonia monooxygenase; KEGG: eca:ECA4176 hypothetical protein YP_002985878.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA4175 hypothetical protein YP_002985879.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA4174 hypothetical protein YP_002985880.1 catalyzes the hydrolysis of phosphatidylcholine YP_002985881.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_002985882.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4171 threonine efflux system YP_002985883.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4170 homoserine/homoserine lactone efflux protein YP_002985884.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_002985885.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; KEGG: eca:ECA4168 sugar phosphatase YP_002985886.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002985887.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_002985888.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_002985889.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_002985890.1 PFAM: pirin; KEGG: eca:ECA4162 hypothetical protein YP_002985891.1 PFAM: protein of unknown function DUF323; KEGG: plu:plu0187 CpmF protein involved in carbapenem resistance YP_002985892.1 KEGG: sgl:SG0585 hypothetical protein YP_002985893.1 PFAM: oligopeptide transporter OPT superfamily protein; KEGG: vei:Veis_1103 oligopeptide transporter OPT superfamily protein YP_002985894.1 PFAM: protein of unknown function DUF1177; KEGG: vei:Veis_1102 hypothetical protein YP_002985895.1 PFAM: AroM family protein; KEGG: spe:Spro_1025 hypothetical protein YP_002985896.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_002985897.1 KEGG: bja:blr1357 peptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002985898.1 KEGG: bar:GBAA4733 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002985899.1 TIGRFAM: amidohydrolase; PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: scl:sce8630 amidohydrolase YP_002985900.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: bha:BH0030 oligopeptide ABC transporter (permease) YP_002985901.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: dde:Dde_1184 dipeptide ABC transporter permease protein YP_002985902.1 PFAM: extracellular solute-binding protein family 5; KEGG: bha:BH0031 oligopeptide ABC transporter (oligopeptide-binding protein) YP_002985903.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_A1843 transcription regulator, IclR family YP_002985904.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: spe:Spro_4652 LacI family transcription regulator YP_002985905.1 KEGG: eca:ECA1839 gluconokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_002985906.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: yen:YE4021 gluconate permease YP_002985907.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_002985908.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002985909.1 PFAM: beta-lactamase; KEGG: pde:Pden_1080 beta-lactamase YP_002985910.1 PFAM: NikR nickel binding; CopG domain protein DNA-binding domain protein; KEGG: azo:azo3128 nickel responsive regulator YP_002985911.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: msu:MS0467 SmtA protein YP_002985912.1 TIGRFAM: nickel ABC transporter periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5; KEGG: pmr:PMI2947 ABC transporter. substrate-binding protein YP_002985913.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pmr:PMI2946 ABC-transporter permease YP_002985914.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pmr:PMI2945 ABC transporter permease YP_002985915.1 KEGG: eca:ECA4152 two-component system sensor kinase; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein YP_002985916.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002985917.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_002985918.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002985919.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002985920.1 KEGG: eca:ECA4147 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_002985921.1 KEGG: cko:CKO_01694 hypothetical protein YP_002985922.1 PFAM: cytochrome B561; KEGG: pmr:PMI0066 oxidoreductase, cytochrome b subunit YP_002985923.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pmr:PMI0067 oxidoreductase, Fe-S subunit YP_002985924.1 KEGG: eck:EC55989_1839 hypothetical protein YP_002985925.1 KEGG: pmr:PMI0069 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase ; aldehyde ferredoxin oxidoreductase; SMART: aldehyde ferredoxin oxidoreductase YP_002985926.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pmr:PMI0070 oxidoreductase, Fe-S subunit YP_002985927.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002985928.1 KEGG: eca:ECA4139 thiosulfate sulfurtransferase; PFAM: rhodanese; SMART: rhodanese YP_002985929.1 KEGG: ypp:YPDSF_4129 endonuclease YP_002985931.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: lch:Lcho_1614 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_002985932.1 KEGG: spe:Spro_2163 diguanylate phosphodiesterase YP_002985933.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: mmw:Mmwyl1_1602 periplasmic binding protein/LacI transcriptional regulator YP_002985934.1 PFAM: inositol monophosphatase; KEGG: mmw:Mmwyl1_1604 inositol-phosphate phosphatase YP_002985935.1 KEGG: mmw:Mmwyl1_1605 ABC transporter periplasmic solute-binding protein YP_002985936.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mmw:Mmwyl1_1606 ABC transporter YP_002985937.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mmw:Mmwyl1_1607 binding-protein-dependent transport systems inner membrane component YP_002985938.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: ppg:PputGB1_3154 major facilitator transporter YP_002985939.1 PFAM: conserved hypothetical protein; KEGG: sew:SeSA_A3867 YiaL YP_002985940.1 PFAM: dihydrodipicolinate synthetase; KEGG: efe:EFER_0075 dihydrodipicolinate synthetase (DHDPS) YP_002985941.1 KEGG: plu:plu3694 hypothetical protein YP_002985942.1 PFAM: plasmid stabilization system; KEGG: eca:ECA1466 hypothetical protein YP_002985943.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: eca:ECA1467 hypothetical protein YP_002985944.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002985945.1 PFAM: zinc finger CHC2-family protein; DNA primase catalytic core domain; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; KEGG: plu:plu3714 hypothetical protein YP_002985946.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3401 phage regulatory protein YP_002985947.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_002985948.1 KEGG: plu:plu3717 hypothetical protein YP_002985949.1 KEGG: plu:plu3718 hypothetical protein YP_002985950.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_002985951.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_002985952.1 KEGG: eca:ECA4136 maltodextrin phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_002985953.1 amylomaltase; acts to release glucose from maltodextrins YP_002985954.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002985955.1 KEGG: eca:ECA4133 gluconate periplasmic binding protein YP_002985956.1 KEGG: eca:ECA4132 biotin biosynthesis protein; TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold YP_002985957.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: eca:ECA4122 RNA binding protein YP_002985958.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: eca:ECA4119 acyltransferase YP_002985959.1 PFAM: sulfatase; KEGG: asu:Asuc_0556 sulfatase YP_002985960.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: spc:Sputcn32_3809 transcription elongation factor GreB YP_002985961.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002985962.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002985963.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002985964.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002985965.1 PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: eca:ECA4104 heat shock protein YP_002985966.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: eca:ECA4103 hydrolase YP_002985967.1 PFAM: Intracellular growth attenuator IgaA; KEGG: eca:ECA4102 intracellular growth attenuator protein YP_002985968.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002985969.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_002985970.1 KEGG: eca:ECA4098 hypothetical protein YP_002985971.1 PFAM: fimbrial assembly family protein; KEGG: spe:Spro_4609 fimbrial assembly family protein YP_002985972.1 KEGG: eca:ECA4096 hypothetical protein YP_002985973.1 KEGG: eca:ECA4095 hypothetical protein YP_002985974.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_002985975.1 PFAM: shikimate kinase; KEGG: esa:ESA_04351 shikimate kinase I YP_002985976.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002985977.1 PFAM: sporulation domain protein; KEGG: eca:ECA4091 hypothetical protein YP_002985978.1 KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_002985979.1 KEGG: eum:ECUMN_3844 D-ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase YP_002985980.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002985981.1 KEGG: kpe:KPK_0361 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib YP_002985982.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA4077 mandelate racemase / muconate lactonizing enzyme YP_002985983.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: eca:ECA4071 peptidyl-prolyl cis-trans isomerase A (rotamase A) YP_002985984.1 KEGG: ajs:Ajs_4122 diguanylate cyclase; TIGRFAM: diguanylate cyclase; hemerythrin-like metal-binding protein; PFAM: GGDEF domain containing protein; hemerythrin HHE cation binding domain protein; SMART: GGDEF domain containing protein YP_002985985.1 KEGG: eca:ECA1072 glutathione S-transferase YP_002985986.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA3563 hypothetical protein YP_002985987.1 KEGG: eca:ECA4070 pectate lyase YP_002985988.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: eca:ECA4069 pectate lyase III YP_002985989.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: eca:ECA4069 pectate lyase III YP_002985990.1 PFAM: pyridoxal-dependent decarboxylase; KEGG: vvu:VV2_1425 glutamate decarboxylase YP_002985991.1 KEGG: fph:Fphi_0374 hypothetical protein YP_002985992.1 KEGG: dal:Dalk_2018 PAS/PAC sensor hybrid histidine kinase YP_002985993.1 PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_3861 major facilitator transporter YP_002985994.1 PFAM: glycoside hydrolase family 19; KEGG: pap:PSPA7_2430 lytic enzyme YP_002985995.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: smt:Smal_2105 sigma54 specific transcriptional regulator YP_002985996.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: swd:Swoo_2358 AraC family transcriptional regulator YP_002985997.1 KEGG: bur:Bcep18194_B1924 hypothetical protein YP_002985998.1 KEGG: pin:Ping_2136 hypothetical protein YP_002985999.1 KEGG: lch:Lcho_2130 hypothetical protein YP_002986002.1 KEGG: bte:BTH_II1638 hypothetical protein YP_002986003.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: yen:YE3958 para-aminobenzoate synthase component II YP_002986004.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_002986005.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002986006.1 PFAM: OsmC family protein; KEGG: eca:ECA4063 hypothetical protein YP_002986007.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: eca:ECA4062 phosphoribulokinase YP_002986008.1 PFAM: protein of unknown function UPF0270; KEGG: set:SEN3290 hypothetical protein YP_002986009.1 PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA4060 hydrolase YP_002986010.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA4059 hypothetical protein YP_002986011.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4058 ABC transporter ATP-binding protein YP_002986012.1 required for KefB activity YP_002986013.1 involved in potassium efflux YP_002986014.1 KEGG: eca:ECA4055 hypothetical protein YP_002986015.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_3766 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002986016.1 TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region; KEGG: eta:ETA_25540 ethanolamin permease YP_002986017.1 PFAM: aminoglycoside phosphotransferase; KEGG: eta:ETA_25530 hypothetical protein YP_002986018.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eta:ETA_25520 AraC family transcriptional regulator YP_002986019.1 PFAM: SlyX family protein; KEGG: eta:ETA_31750 host factor for lysis of phiX174 infection SlyX YP_002986020.1 rotamase YP_002986021.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: rlt:Rleg2_5225 GntR family transcriptional regulator YP_002986022.1 KEGG: vei:Veis_2840 hypothetical protein YP_002986023.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eta:ETA_23610 hydrolase YP_002986024.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: ara:Arad_8818 amino acid ABC transporter YP_002986025.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ara:Arad_8820 amino acid ABC transporter YP_002986026.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ara:Arad_8821 amino acid ABC transporter YP_002986027.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA4045 sensor protein BasS/PmrB YP_002986028.1 response regulator in two-component regulatory system with BasS YP_002986029.1 PFAM: YheO domain protein; KEGG: eca:ECA4042 DNA-binding protein YP_002986030.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002986031.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002986032.1 TIGRFAM: sulfur relay protein TusB/DsrH; PFAM: DsrH family protein; KEGG: eca:ECA4039 intracellular sulfur oxidation protein YP_002986033.1 TIGRFAM: ribosomal protein S12; PFAM: ribosomal protein S12/S23; KEGG: kpn:KPN_03727 30S ribosomal protein S12 YP_002986034.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002986035.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002986036.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002986037.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA4034 bacterioferritin-associated ferredoxin YP_002986038.1 iron storage protein YP_002986039.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002986040.1 PFAM: ribosomal protein L3; KEGG: eca:ECA4031 50S ribosomal protein L3 YP_002986041.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002986042.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002986043.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002986044.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002986045.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002986046.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002986047.1 TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16; KEGG: eca:ECA4024 50S ribosomal protein L16 YP_002986048.1 TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: ypi:YpsIP31758_3907 50S ribosomal protein L29 YP_002986049.1 PFAM: ribosomal protein S17; KEGG: eum:ECUMN_3784 30S ribosomal subunit protein S17 YP_002986050.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002986051.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002986052.1 PFAM: ribosomal protein L5; KEGG: eca:ECA4019 50S ribosomal protein L5 YP_002986053.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002986054.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002986055.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002986056.1 binds 5S rRNA along with protein L5 and L25 YP_002986057.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002986058.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002986059.1 late assembly protein YP_002986060.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002986061.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002986062.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002986063.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002986064.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002986065.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002986066.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002986067.1 PFAM: protein of unknown function DUF331; KEGG: set:SEN3239 hypothetical protein YP_002986068.1 PFAM: Integrase catalytic region; KEGG: son:SO_A0151 ISSod13, transposase YP_002986069.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: eca:ECA4003 large-conductance mechanosensitive channel YP_002986070.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002986071.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_002986072.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: sdy:SDY_3464 methionyl-tRNA formyltransferase YP_002986073.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002986074.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: eca:ECA3998 hypothetical protein YP_002986075.1 PFAM: protein of unknown function DUF494; KEGG: eca:ECA3997 hypothetical protein YP_002986076.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: spe:Spro_4508 DNA topoisomerase type IA Zn finger domain-containing protein YP_002986077.1 PFAM: SUA5/yciO/yrdC domain; KEGG: eca:ECA3996 DNA topoisomerase YP_002986078.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: shikimate dehydrogenase substrate binding domain protein; shikimate/quinate 5-dehydrogenase; KEGG: eca:ECA3995 shikimate 5-dehydrogenase YP_002986079.1 PFAM: protein of unknown function DUF1488; KEGG: sed:SeD_A3767 periplasmic protein YP_002986080.1 KEGG: eca:ECA3993 transferase YP_002986081.1 KEGG: stm:STM0948 cytoplasmic protein YP_002986082.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002986083.1 KEGG: eca:ECA3991 malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase YP_002986084.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: eca:ECA3990 isocitrate lyase YP_002986085.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_002986086.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_002986087.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_002986088.1 KEGG: eba:ebA5917 hypothetical protein YP_002986089.1 KEGG: eba:ebA5228 hypothetical protein YP_002986090.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA3986 AraC family transcription regulator YP_002986091.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA3985 ferrioxamine B receptor YP_002986092.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pfl:PFL_2915 LysR family transcriptional regulator YP_002986093.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfl:PFL_2916 major facilitator family transporter YP_002986094.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; PhoU family protein; KEGG: eca:ECA3983 sodium/phosphate cotransporter YP_002986095.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_002986096.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002986097.1 KEGG: spe:Spro_0410 hypothetical protein YP_002986098.1 KEGG: eca:ECA3977 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM protein YP_002986099.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002986100.1 PFAM: protein of unknown function DUF486; KEGG: eca:ECA3974 hypothetical protein YP_002986101.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_002986102.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002986103.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002986104.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002986105.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002986106.1 PFAM: MscS Mechanosensitive ion channel; KEGG: eca:ECA3967 hypothetical protein YP_002986107.1 KEGG: eca:ECA3966 phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase; PFAM: phosphatidylserine decarboxylase-related YP_002986108.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002986109.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: eum:ECUMN_4696 oligoribonuclease YP_002986110.1 KEGG: pen:PSEEN0738 hypothetical protein YP_002986111.1 KEGG: pfo:Pfl01_0146 hypothetical protein YP_002986112.1 PFAM: peptidase M50; KEGG: pfo:Pfl01_0147 peptidase M50 YP_002986113.1 PFAM: Tail Collar domain protein; KEGG: shn:Shewana3_0167 phage tail collar domain-containing protein YP_002986114.1 PFAM: Tail Collar domain protein; KEGG: shw:Sputw3181_3688 phage tail collar domain-containing protein YP_002986115.1 PFAM: Ig family protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: hch:HCH_03194 outer membrane protein domain-containing protein YP_002986116.1 PFAM: outer membrane efflux protein; KEGG: ppw:PputW619_0676 outer membrane efflux protein YP_002986117.1 TIGRFAM: succinylornithine transaminase family; acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; aminotransferase class I and II; KEGG: spe:Spro_2844 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_002986118.1 KEGG: spe:Spro_2843 arginine succinyltransferase; TIGRFAM: arginine N-succinyltransferase; arginine/ornithine succinyltransferase subunit; PFAM: arginine N-succinyltransferase subunit beta YP_002986119.1 TIGRFAM: succinylglutamic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: abm:ABSDF0357 succinylglutamic semialdehyde dehydrogenase YP_002986120.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002986121.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002986122.1 KEGG: sew:SeSA_A4796 P-18 protein YP_002986123.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2957 pyruvate-flavodoxin oxidoreductase YP_002986124.1 KEGG: kpe:KPK_1714 nitrogenase iron protein; TIGRFAM: nitrogenase iron protein; PFAM: NifH/frxC-family protein YP_002986125.1 KEGG: eca:ECA2955 nitrogenase molybdenum-iron protein alpha chain; TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; PFAM: oxidoreductase/nitrogenase component 1 YP_002986126.1 KEGG: eca:ECA2954 nitrogenase molybdenum-iron protein beta chain; TIGRFAM: nitrogenase molybdenum-iron protein beta chain; PFAM: oxidoreductase/nitrogenase component 1 YP_002986127.1 TIGRFAM: nitrogen fixation protein FixT; PFAM: NifT/FixU family protein; KEGG: eca:ECA2953 nitrogen fixation protein YP_002986128.1 PFAM: dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: eca:ECA2952 nitrogen fixation protein YP_002986129.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: spe:Spro_0463 methyl-accepting chemotaxis sensory transducer YP_002986130.1 TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: oxidoreductase/nitrogenase component 1; KEGG: eca:ECA2949 nitrogenase iron-molybdenum cofactor biosynthesis protein YP_002986131.1 functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe YP_002986132.1 PFAM: dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: eca:ECA2947 nitrogen fixation protein YP_002986134.1 KEGG: rfr:Rfer_1069 hypothetical protein YP_002986135.1 KEGG: rfr:Rfer_1070 hypothetical protein YP_002986136.1 TIGRFAM: Fe-S cluster assembly protein NifU; PFAM: nitrogen-fixing NifU domain protein; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA2946 nitrogen fixation protein YP_002986137.1 KEGG: eca:ECA2945 cysteine desulfurase; TIGRFAM: cysteine desulfurase NifS; PFAM: aminotransferase class V YP_002986138.1 TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: eca:ECA2944 homocitrate synthase YP_002986139.1 KEGG: eca:ECA2943 nitrogenase stabilizing/protective protein YP_002986140.1 PFAM: NifZ family protein; KEGG: eca:ECA2942 nitrogen fixation protein YP_002986141.1 TIGRFAM: nitrogen fixation protein NifM; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: eca:ECA2941 nitrogen fixation protein YP_002986142.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_3129 acetyltransferase YP_002986143.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002986144.1 KEGG: eca:ECA2939 nitrogen fixation regulatory protein; TIGRFAM: nitrogen fixation negative regulator NifL; PAS sensor protein; PFAM: PAS fold domain protein; hypothetical protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; PAS domain containing protein YP_002986145.1 KEGG: eca:ECA2938 nif-specific regulatory protein; TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase AAA; SMART: GAF domain protein; ATPase AAA YP_002986146.1 TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: dinitrogenase iron-molybdenum cofactor biosynthesis protein; radical SAM protein; KEGG: eca:ECA2937 femo cofactor biosynthesis protein YP_002986147.1 PFAM: NifQ family protein; KEGG: eca:ECA2936 nitrogen fixation protein YP_002986148.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: spe:Spro_4199 DNA-binding transcriptional regulator YP_002986149.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: spe:Spro_4200 amidohydrolase YP_002986150.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: spe:Spro_4201 amidohydrolase YP_002986151.1 TIGRFAM: AbgT transporter family; PFAM: AbgT transporter; KEGG: spe:Spro_4202 aminobenzoyl-glutamate transporter YP_002986152.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: eca:ECA3168 transcriptional regulator of organic hydroperoxide resistance gene ohr YP_002986153.1 PFAM: OsmC family protein; KEGG: eca:ECA3167 organic hydroperoxide resistance protein YP_002986154.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2153 ABC transporter ATP-binding protein YP_002986155.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2154 ABC transporter permease YP_002986156.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2155 acetyltransferase YP_002986157.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA2156 ABC transporter substrate-binding protein YP_002986158.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA2157 ABC transporter substrate-binding protein YP_002986159.1 KEGG: eca:ECA2158 hypothetical protein YP_002986160.1 PFAM: Luciferase-like monooxygenase; KEGG: eca:ECA2161 luciferase-like monooxygenase YP_002986161.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: eca:ECA3947 D-isomer specific 2-hydroxyacid dehydrogenase YP_002986162.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: eca:ECA3940 4Fe-4S binding protein YP_002986163.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: eca:ECA3939 hypothetical protein YP_002986164.1 PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 ATPase YP_002986165.1 PFAM: cell wall hydrolase/autolysin; peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; peptidoglycan-binding LysM; KEGG: eca:ECA3937 N-acetylmuramoyl-L-alanine amidase YP_002986166.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002986167.1 KEGG: eca:ECA3935 tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase YP_002986168.1 Stimulates the elongation of poly(A) tails YP_002986169.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002986170.1 KEGG: eca:ECA3932 FtsH protease regulator HflK; TIGRFAM: HflK protein; PFAM: band 7 protein; SMART: band 7 protein YP_002986171.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_002986172.1 KEGG: eca:ECA3930 hypothetical protein YP_002986173.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002986174.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: eca:ECA3928 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase YP_002986175.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_002986176.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002986177.1 PFAM: protein of unknown function DUF179; KEGG: eca:ECA3925 hypothetical protein YP_002986178.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_002986179.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002986180.1 PFAM: endonuclease I; KEGG: esa:ESA_00397 hypothetical protein YP_002986181.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: eca:ECA3921 hypothetical protein YP_002986182.1 KEGG: ypg:YpAngola_A3347 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase YP_002986183.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002986184.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_4593 hypothetical protein YP_002986185.1 TIGRFAM: transketolase; PFAM: transketolase central region; transketolase; KEGG: eca:ECA0861 transketolase YP_002986186.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002986187.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002986188.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002986189.1 PFAM: MscS Mechanosensitive ion channel; Conserved TM helix repeat-containing protein; KEGG: eca:ECA3910 mechanosensitive ion channel YP_002986190.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: efe:EFER_2855 arginine transporter YP_002986191.1 PFAM: protein of unknown function DUF541; KEGG: eca:ECA3908 hypothetical protein YP_002986192.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002986193.1 KEGG: eca:ECA3906 ribose-5-phosphate isomerase A; TIGRFAM: ribose 5-phosphate isomerase; PFAM: ribose 5-phosphate isomerase YP_002986194.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002986195.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3902 methyl-accepting chemotaxis protein YP_002986196.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_002986197.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_002986198.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: eca:ECA3899 Trp operon repressor YP_002986199.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002986200.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_002986201.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA3896 right origin-binding protein YP_002986202.1 PFAM: CreA family protein; KEGG: eca:ECA3894 hypothetical protein YP_002986203.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: eca:ECA3893 two-component response regulator YP_002986204.1 member of the SPOUT superfamily of methyltransferases YP_002986205.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002986206.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002986207.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002986208.1 PFAM: protein of unknown function DUF328; KEGG: eca:ECA3888 hypothetical protein YP_002986209.1 KEGG: eca:ECA3887 transaldolase B; TIGRFAM: transaldolase; PFAM: transaldolase YP_002986210.1 KEGG: eca:ECA3886 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_002986211.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002986212.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: spe:Spro_0690 major facilitator transporter YP_002986213.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: eca:ECA3883 hypothetical protein YP_002986214.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002986215.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002986216.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002986217.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_002986218.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002986219.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002986220.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002986221.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002986222.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: eca:ECA3874 FkbP-type 16 kDa peptidyl-prolyl cis-trans isomerase YP_002986223.1 KEGG: eca:ECA3873 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein YP_002986224.1 KEGG: eca:ECA3872 dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase YP_002986225.1 TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: yen:YE0621 carbamoyl phosphate synthase small subunit YP_002986226.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002986227.1 KEGG: ent:Ent638_0389 hypothetical protein YP_002986229.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: spe:Spro_0717 lysine exporter protein LysE/YggA YP_002986230.1 PFAM: protein of unknown function DUF1212; KEGG: eca:ECA3866 hypothetical protein YP_002986231.1 KEGG: eca:ECA3865 hypothetical protein YP_002986232.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_002986233.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_002986234.1 protein associated with Co2+ and Mg2+ efflux YP_002986235.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002986236.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002986237.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_002986238.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002986239.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002986240.1 PFAM: pseudouridine synthase; KEGG: eca:ECA3854 ribosomal large subunit pseudouridine synthase A YP_002986241.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_002986242.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_002986243.1 PFAM: extracellular ligand-binding receptor; KEGG: kpe:KPK_4384 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein YP_002986244.1 PFAM: inner-membrane translocator; KEGG: kpe:KPK_4385 branched-chain amino acid ABC transporter permease YP_002986245.1 PFAM: inner-membrane translocator; KEGG: kpe:KPK_4386 branched-chain amino acid ABC transporter permease YP_002986246.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: kpn:KPN_00302 ATP-binding component of high-affinity branched-chain amino acid transporter YP_002986247.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: kpn:KPN_00301 ATP-binding component of leucine transport YP_002986248.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA3850 hypothetical protein YP_002986249.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bpt:Bpet1343 LysR family transcriptional regulator YP_002986250.1 PFAM: threonyl/alanyl tRNA synthetase SAD; KEGG: spe:Spro_3159 threonyl/alanyl tRNA synthetase SAD YP_002986251.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: plu:plu1236 hypothetical protein YP_002986252.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_002986253.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: eca:ECA3848 acetolactate synthase catalytic subunit YP_002986254.1 with TbpA and ThiP is part of the thiamine and TPP transporter YP_002986255.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002986256.1 part of the thiamine and TPP transporter tbpA-thiPQ YP_002986257.1 activates sgrS under glucose-phosphate stress conditions YP_002986259.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_002986260.1 TIGRFAM: tryptophanase leader peptide YP_002986261.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; Siderophore-interacting protein; KEGG: cko:CKO_00978 hypothetical protein YP_002986262.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002986263.1 TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein; KEGG: eca:ECA3833 isopropylmalate isomerase large subunit YP_002986264.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002986265.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002986266.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA3830 AMP-binding protein YP_002986267.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_002986268.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002986269.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002986270.1 PFAM: protein of unknown function DUF1144; KEGG: eca:ECA3826 hypothetical protein YP_002986272.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002986273.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: eca:ECA3823 S-adenosyl-methyltransferase MraW YP_002986274.1 membrane bound cell division protein at septum containing leucine zipper motif YP_002986275.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: eca:ECA3821 peptidoglycan synthetase YP_002986276.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002986277.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: eca:ECA3819 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_002986278.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002986279.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002986280.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_002986281.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002986282.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002986284.1 involved in septum formation YP_002986285.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_002986286.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002986287.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002986288.1 PFAM: protein of unknown function DUF721; KEGG: eca:ECA3808 hypothetical protein YP_002986289.1 secM translational pause allows for the initiation of secA translation YP_002986290.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002986292.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: eca:ECA3805 nucleoside triphosphate pyrophosphohydrolase YP_002986293.1 PFAM: protein of unknown function DUF329; KEGG: eca:ECA3804 hypothetical protein YP_002986294.1 PFAM: protein of unknown function DUF1342; KEGG: eca:ECA3803 hypothetical protein YP_002986295.1 KEGG: eca:ECA3802 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_002986296.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002986297.1 PFAM: type II secretion system protein; KEGG: eca:ECA3800 type IV pilin biogenesis protein YP_002986298.1 PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: eca:ECA3799 hypothetical protein YP_002986299.1 KEGG: eca:ECA3798 major pilin subunit YP_002986300.1 KEGG: spe:Spro_0779 quinolinate phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_002986301.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: eca:ECA3796 nucleoside-specific channel-forming protein YP_002986302.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: yps:YPTB0709 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002986303.1 involved in regulation of beta-lactamase; signaling protein YP_002986304.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA3791 aromatic amino acid transporter YP_002986306.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002986307.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002986308.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_002986309.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: cko:CKO_03256 dihydrolipoamide dehydrogenase YP_002986310.1 PFAM: dienelactone hydrolase; KEGG: eca:ECA3785 hypothetical protein YP_002986311.1 PFAM: MmgE/PrpD family protein; KEGG: eca:ECA3784 hypothetical protein YP_002986312.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA3783 AraC family transcription regulator YP_002986313.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002986314.1 PFAM: esterase; KEGG: mxa:MXAN_1690 esterase YP_002986315.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002986316.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3777 hypothetical protein YP_002986317.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA3767 short-chain dehydrogenase YP_002986318.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3766 hypothetical protein YP_002986320.1 KEGG: eca:ECA3765 hypothetical protein YP_002986321.1 PFAM: Na+/solute symporter; KEGG: eca:ECA3764 sodium:solute symporter YP_002986322.1 PFAM: dihydrodipicolinate synthetase; KEGG: eca:ECA3763 dihydrodipicolinate synthase YP_002986323.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA3762 alcohol dehydrogenase YP_002986324.1 PFAM: type III effector Hrp-dependent outers; KEGG: eca:ECA3761 hypothetical protein YP_002986325.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002986326.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA3759 DeoR family transcriptional regulator YP_002986327.1 KEGG: vei:Veis_3591 hypothetical protein YP_002986328.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: lch:Lcho_0454 LacI family transcription regulator YP_002986329.1 PFAM: ROK family protein; KEGG: kpe:KPK_1046 ROK family protein YP_002986330.1 PFAM: glycosyl hydrolase 38 domain protein; glycoside hydrolase family 38; glycoside hydrolase family 38 central region; KEGG: bha:BH0791 alpha-mannosidase YP_002986331.1 PFAM: extracellular solute-binding protein family 1; KEGG: yen:YE0460 sugar binding protein YP_002986332.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: yen:YE0461 sugar transporter, permease YP_002986333.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: yps:YPTB0503 ABC type sugar transporter, permease YP_002986334.1 PFAM: ABC transporter; TOBE domain protein; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: yps:YPTB0504 sugar ABC transporter ATP-binding protein YP_002986335.1 PFAM: conserved hypothetical protein; KEGG: mmw:Mmwyl1_4122 hypothetical protein YP_002986336.1 PFAM: periplasmic solute binding protein; KEGG: ecp:ECP_3824 periplasmic binding protein YP_002986337.1 PFAM: ABC transporter; KEGG: ecp:ECP_3823 ABC-transporter membrane protein YP_002986338.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ecp:ECP_3822 ABC-transporter ATP-binding protein YP_002986340.1 PFAM: extracellular solute-binding protein family 1; KEGG: bvi:Bcep1808_7294 tungstate/molybdate binding protein YP_002986341.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sgl:SG0292 sulfate/molybdate ABC transporter permease YP_002986342.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: eca:ECA3753 hypothetical protein YP_002986343.1 KEGG: eca:ECA3752 hypothetical protein YP_002986344.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3751 extracellular solute-binding protein YP_002986345.1 KEGG: eca:ECA3750 hypothetical protein YP_002986346.1 PFAM: glycosyl hydrolase family 88; KEGG: eca:ECA3749 plant-inducible protein YP_002986347.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: eca:ECA3748 ABC transporter ATP-binding protein YP_002986348.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3747 ABC transporter membrane spanning protein YP_002986349.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3746 ABC transporter membrane spanning protein YP_002986350.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA3745 LacI family transcriptional regulator YP_002986352.1 KEGG: bac:BamMC406_1027 hypothetical protein YP_002986353.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: bpm:BURPS1710b_A1998 NAD(P)H-flavin oxidoreductase YP_002986355.1 KEGG: bpt:Bpet4285 mobile mitochondrial group II intron of COX1 which IS involved in pre-mRNA splicing and in deletion of introns from mitochondrial DNA; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); intron maturase type II; SMART: HNH nuclease YP_002986356.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cko:CKO_03842 single-stranded DNA-binding protein YP_002986357.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrsubunit betas scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002986358.1 PFAM: protein of unknown function UPF0047; KEGG: eca:ECA3688 hypothetical protein YP_002986359.1 KEGG: eca:ECA3374 signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_002986360.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0183 methyl-accepting chemotaxis protein YP_002986361.1 KEGG: plu:plu1782 hypothetical protein YP_002986362.1 TIGRFAM: CRISPR-associated protein, Csy4 family; KEGG: eca:ECA3684 hypothetical protein YP_002986363.1 TIGRFAM: CRISPR-associated protein, Csy3 family; KEGG: eca:ECA3683 hypothetical protein YP_002986364.1 TIGRFAM: CRISPR-associated protein, Csy2 family; KEGG: eca:ECA3682 hypothetical protein YP_002986365.1 TIGRFAM: CRISPR-associated protein, Csy1 family; KEGG: eca:ECA3681 hypothetical protein YP_002986366.1 TIGRFAM: CRISPR-associated helicase Cas3 family; KEGG: eca:ECA3680 hypothetical protein YP_002986367.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: eca:ECA3679 hypothetical protein YP_002986368.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002986369.1 PFAM: protein of unknown function DUF161; KEGG: eca:ECA3669 hypothetical protein YP_002986370.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: eca:ECA3668 transcription regulator AsnC YP_002986371.1 KEGG: spe:Spro_4447 arogenate dehydratase; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_002986372.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA4414 hypothetical protein YP_002986373.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002986374.1 KEGG: eca:ECA3664 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: ATPase AAA YP_002986375.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA3663 quinone oxidoreductase, NADPH-dependent YP_002986376.1 TIGRFAM: phage shock protein G; KEGG: yps:YPTB0373 phage shock protein G YP_002986377.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase; KEGG: eca:ECA3660 tRNA-dihydrouridine synthase A YP_002986378.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: spe:Spro_4489 GntR family transcriptional regulator YP_002986379.1 PFAM: extracellular solute-binding protein family 1; KEGG: spe:Spro_4488 extracellular solute-binding protein YP_002986380.1 KEGG: eta:ETA_31180 hypothetical protein YP_002986381.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_4486 binding-protein-dependent transport systems inner membrane component YP_002986382.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eta:ETA_31160 ABC transporter permease, fragment YP_002986383.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: spe:Spro_4484 ABC transporter-related protein YP_002986384.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; PhoU family protein; KEGG: eta:ETA_31140 sodium/phosphate cotransporter YP_002986385.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002986386.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002986387.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA3649 transcriptional repressor of carbon metabolism YP_002986388.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIsubunit alpha; KEGG: eca:ECA3648 PTS system, cellobiose-specific IIA component YP_002986389.1 KEGG: eca:ECA3647 PTS system, lichenan-specific IIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_002986390.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA3646 6-phospho-beta-glucosidase YP_002986391.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: eca:ECA3645 PTS system, lichenan-specific IIB component YP_002986392.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA3644 GntR family transcriptional regulator YP_002986393.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3643 GnaT-family acetyltransferase YP_002986394.1 controls transcription of galETKM YP_002986395.1 PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: esa:ESA_02544 hypothetical protein YP_002986396.1 TIGRFAM: PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose subfamily, IIsubunit alpha; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: esa:ESA_02545 hypothetical protein YP_002986397.1 PFAM: glycoside hydrolase family 1; KEGG: esa:ESA_02546 hypothetical protein YP_002986398.1 PFAM: glycoside hydrolase family 1; KEGG: esa:ESA_02547 hypothetical protein YP_002986399.1 transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_002986400.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3640 hypothetical protein YP_002986401.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3639 acyltransferase YP_002986402.1 PFAM: entericidin EcnAB; KEGG: eca:ECA3638 entericidin A precursor YP_002986403.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002986404.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002986405.1 PFAM: protein of unknown function DUF167; KEGG: eca:ECA3630 hypothetical protein YP_002986406.1 PFAM: protein of unknown function YGGT; KEGG: eca:ECA3629 hypothetical protein YP_002986407.1 KEGG: eca:ECA3628 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_002986408.1 PFAM: alanine racemase domain protein; KEGG: eca:ECA3627 alanine racemase YP_002986409.1 KEGG: eca:ECA3626 type II/IV secretion system protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: ATPase AAA YP_002986410.1 PFAM: amidohydrolase; amidohydrolase; KEGG: esa:ESA_03405 hypothetical protein YP_002986411.1 PFAM: purine catabolism PurC domain protein; helix-turn-helix Fis-type; KEGG: bte:BTH_II1640 DNA-binding protein YP_002986412.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: esa:ESA_03406 cytosine permease YP_002986414.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: bsu:BSU02210 hypothetical protein YP_002986415.1 PFAM: radical SAM protein; KEGG: nar:Saro_3029 radical SAM family protein YP_002986416.1 PFAM: radical SAM protein; KEGG: nar:Saro_3029 radical SAM family protein YP_002986417.1 KEGG: hypothetical protein LOC777554 YP_002986418.1 PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_4401 major facilitator transporter YP_002986419.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3624 methyl-accepting chemotaxis protein YP_002986420.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_002986421.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_002986422.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002986424.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_002986425.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3615 methyl-accepting chemotaxis protein YP_002986426.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_002986427.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002986428.1 binds single-stranded DNA at the primosome assembly site YP_002986429.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002986430.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002986431.1 PFAM: protein of unknown function DUF488; KEGG: spe:Spro_0450 hypothetical protein YP_002986432.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: eca:ECA3608 hypothetical protein YP_002986433.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_002986434.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: azc:AZC_3883 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_002986435.1 PFAM: ANTAR domain protein; KEGG: bpy:Bphyt_5752 response regulator receiver and ANTAR domain protein YP_002986436.1 KEGG: bpy:Bphyt_5753 ABC branched chain amino acid family transporter periplasmic ligand binding protein YP_002986437.1 PFAM: acetamidase/Formamidase; KEGG: bpy:Bphyt_5754 acetamidase/formamidase YP_002986438.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bpy:Bphyt_5755 ABC transporter YP_002986439.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bpy:Bphyt_5756 ABC transporter YP_002986440.1 PFAM: inner-membrane translocator; KEGG: bpy:Bphyt_5757 inner-membrane translocator YP_002986441.1 PFAM: inner-membrane translocator; KEGG: bpy:Bphyt_5758 inner-membrane translocator YP_002986442.1 PFAM: extracellular ligand-binding receptor; KEGG: bpy:Bphyt_5759 UreA/short-chain amide transporter substrate-binding protein precursor YP_002986444.1 KEGG: ecd:ECDH10B_0005 hypothetical protein YP_002986447.1 Involved in anaerobic NO protection and iron metabolism YP_002986448.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_002986449.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_002986450.1 KEGG: eca:ECA3600 hypothetical protein YP_002986451.1 PFAM: protein of unknown function DUF1107; KEGG: eca:ECA3599 hypothetical protein YP_002986452.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA3598 hypothetical protein YP_002986453.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_002986454.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: eca:ECA3596 hypothetical protein YP_002986455.1 PFAM: protein of unknown function DUF490; KEGG: eca:ECA3595 hypothetical protein YP_002986456.1 PFAM: AIG2 family protein; KEGG: eca:ECA3594 hypothetical protein YP_002986457.1 PFAM: inorganic pyrophosphatase; KEGG: kpe:KPK_5044 inorganic diphosphatase YP_002986458.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3592 methyl-accepting chemotaxis protein YP_002986459.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002986460.1 KEGG: eca:ECA3590 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; TIGRFAM: dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase YP_002986461.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002986462.1 PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: eca:ECA3588 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002986463.1 PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: eca:ECA3587 signal transduction protein YP_002986464.1 PFAM: adenylate cyclase; KEGG: eca:ECA3586 hypothetical protein YP_002986465.1 PFAM: glutamate-ammonia ligase adenylyltransferase; GlnD PII-uridylyltransferase; KEGG: eca:ECA3585 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002986466.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_002986467.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002986468.1 KEGG: ypg:YpAngola_A2743 hypothetical protein YP_002986469.1 KEGG: eca:ECA3581 hypothetical protein YP_002986470.1 KEGG: cko:CKO_00388 hypothetical protein YP_002986471.1 KEGG: eca:ECA3579 methyl-accepting chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; PAC repeat-containing protein; PAS domain containing protein; histidine kinase HAMP region domain protein YP_002986472.1 KEGG: eca:ECA3578 D-galactarate dehydratase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; SAF domain protein YP_002986473.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA3577 glucarate transporter YP_002986474.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA3576 glucarate dehydratase YP_002986475.1 KEGG: eca:ECA3575 glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: mandelate racemase/muconate lactonizing protein YP_002986476.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_002986477.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_002986478.1 KEGG: eca:ECA3572 glycerate kinase 2; TIGRFAM: glycerate kinase; PFAM: glycerate kinase YP_002986479.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002986480.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002986481.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_002986482.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_002986483.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002986484.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002986485.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3560 oligogalacturonide transporter YP_002986486.1 PFAM: glycosyl hydrolase family 88; KEGG: eca:ECA3559 plant-inducible protein YP_002986487.1 PFAM: beta-lactamase; KEGG: eca:ECA3555 metallo hydrolase YP_002986488.1 KEGG: eca:ECA3554 hypothetical protein YP_002986489.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: yps:YPTB0758 6-pyruvoyl tetrahydrobiopterin synthase family protein YP_002986490.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: FAD-binding domain protein; flavodoxin/nitric oxide synthase; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: eca:ECA3547 sulfite reductase subunit alpha YP_002986491.1 hemoprotein; NADPH dependent; with the subunit alpha (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002986492.1 TIGRFAM: phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: yps:YPTB0761 phosphoadenosine phosphosulfate reductase YP_002986493.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA3544 siroheme synthase [includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase] YP_002986494.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002986495.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002986496.1 KEGG: spe:Spro_0820 adenylyl-sulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: adenylylsulfate kinase YP_002986497.1 KEGG: spe:Spro_0821 hypothetical protein YP_002986498.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002986499.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: eca:ECA3535 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002986500.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002986501.1 catalyzes the modification of U13 in tRNA(Glu) YP_002986502.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002986503.1 PFAM: peptidase M23; peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: eca:ECA3531 lipoprotein NlpD YP_002986504.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_002986505.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002986506.1 PFAM: protein of unknown function UPF0066; KEGG: ypg:YpAngola_A3409 hypothetical protein YP_002986507.1 KEGG: eca:ECA3527 outer membrane lipoprotein YP_002986508.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; substrate-binding region of ABC-type glycine betaine transporter; KEGG: eca:ECA3526 DL-methionine transporter substrate-binding subunit YP_002986509.1 part of the MetNIQ methionine uptake system YP_002986510.1 KEGG: sek:SSPA0246 ABC transporter ATP-binding protein; TIGRFAM: D-methionine ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_002986511.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_002986512.1 KEGG: stm:STM0948 cytoplasmic protein YP_002986513.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA3522 alpha-ketoglutarate transporter YP_002986514.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002986515.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: eca:ECA3519 acyl-CoA synthetase YP_002986516.1 PFAM: DTW domain containing protein; KEGG: eca:ECA3518 hypothetical protein YP_002986517.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: eca:ECA3517 thioredoxin 2 YP_002986518.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: spe:Spro_3745 methyltransferase YP_002986519.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3513 multidrug resistance protein B YP_002986520.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA3512 multidrug resistance protein A YP_002986521.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_002986522.1 KEGG: eca:ECA3510 hypothetical protein YP_002986523.1 PFAM: AzlC family protein; KEGG: eca:ECA3509 amino acid transporter YP_002986524.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3508 transporter YP_002986525.1 with ProVW, part of the high-affinity transporter for the osmoprotectant glycine betaine YP_002986526.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_002986527.1 KEGG: eca:ECA3502 glycine betaine/L-proline transport ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter ATPase; PFAM: ABC transporter; CBS domain containing protein; SMART: ATPase AAA YP_002986528.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: kpe:KPK_2569 permease, cytosine/purine, uracil, thiamine, allantoin family YP_002986529.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eta:ETA_26320 transcriptional regulator, GntR family YP_002986530.1 PFAM: Asp/Glu/hydantoin racemase; KEGG: spe:Spro_0915 Asp/Glu racemase YP_002986531.1 KEGG: spe:Spro_0916 chitin deacetylase; TIGRFAM: urate catabolism protein; PFAM: polysaccharide deacetylase YP_002986532.1 KEGG: eca:ECA3500 hypothetical protein YP_002986533.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002986534.1 KEGG: spe:Spro_0929 hypothetical protein YP_002986535.1 PFAM: gamma-glutamyltranspeptidase; KEGG: eca:ECA3497 gamma-glutamyltranspeptidase YP_002986536.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: eca:ECA3496 transcriptional regulator YP_002986537.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA3495 amino acid ABC transporter substrate-binding protein YP_002986538.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3494 amino acid ABC transporter permease protein YP_002986539.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3493 amino acid ABC transporter permease protein YP_002986540.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3492 amino acid ABC transporter ATP-binding protein YP_002986541.1 PFAM: aminotransferase class V; KEGG: eca:ECA3491 purine catabolism protein YP_002986542.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002986543.1 KEGG: rlt:Rleg2_6114 glutathione S-transferase domain YP_002986544.1 PFAM: Integrase catalytic region; KEGG: son:SO_A0151 ISSod13, transposase YP_002986545.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eca:ECA3489 hypothetical protein YP_002986546.1 catalyzes the transfer of an amino moiety YP_002986547.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_002986548.1 KEGG: eca:ECA3486 enolase-phosphatase; TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase YP_002986549.1 PFAM: acireductone dioxygenase; KEGG: eca:ECA3485 oxidase YP_002986550.1 KEGG: eca:ECA3477 translation initiation factor EIF-2B; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_002986551.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_002986552.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_002986553.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_002986554.1 PFAM: glutamine amidotransferase class-II; KEGG: eca:ECA3472 hypothetical protein YP_002986555.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA3471 hypothetical protein YP_002986556.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002986557.1 KEGG: eca:ECA3467 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_002986559.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_002986560.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002986561.1 KEGG: ent:Ent638_3082 hypothetical protein YP_002986562.1 KEGG: eum:ECUMN_2929 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein YP_002986563.1 PFAM: transcriptional regulator Crl; KEGG: spe:Spro_0966 DNA-binding transcriptional regulator Crl YP_002986564.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002986565.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002986566.1 KEGG: eca:ECA3130 poly(glycerophosphate chain) D-alanine transfer protein YP_002986568.1 PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: eca:ECA3129 peptidoglycan biosynthesis protein YP_002986569.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA3128 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_002986570.1 KEGG: eca:ECA3127 acyl carrier protein YP_002986571.1 PFAM: Ketopantoate reductase ApbA/PanE domain protein; KEGG: bam:Bamb_6421 2-dehydropantoate 2-reductase YP_002986572.1 PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; KEGG: sea:SeAg_B1537 GntR domain protein YP_002986573.1 NAD-binding YP_002986574.1 PFAM: major facilitator superfamily MFS_1; KEGG: sea:SeAg_B1539 probable glucarate transporter YP_002986575.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: set:SEN1435 hexonate dehydrogenase YP_002986576.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: set:SEN1436 dehydratase YP_002986577.1 PFAM: peptidase M24; creatinase; KEGG: ara:Arad_8261 peptidase protein YP_002986578.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bbt:BBta_3717 acetylornithine deacetylase YP_002986579.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: ara:Arad_8264 peptide ABC transporter YP_002986580.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ara:Arad_8265 dipeptide ABC transporter YP_002986581.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: bbt:BBta_3714 nickel ABC transporter permease(NikB) YP_002986582.1 PFAM: extracellular solute-binding protein family 5; KEGG: bbt:BBta_3713 ABC transporter (substrate binding component) YP_002986583.1 PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: ara:Arad_8269 acetylornithine deacetylase protein YP_002986584.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: ara:Arad_8270 transcriptional regulator protein YP_002986585.1 KEGG: efe:EFER_2212 sensory kinase in two-component system with YehT; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: GAF domain protein YP_002986586.1 unknown function; when overproduced it confers drug-resistance YP_002986587.1 PFAM: carbon starvation protein CstA; KEGG: eum:ECUMN_4963 conserved hypothetical protein; inner membrane protein YP_002986588.1 PFAM: protein of unknown function DUF466; KEGG: spe:Spro_0581 hypothetical protein YP_002986589.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: eca:ECA1189 GTP-binding protein YjiA YP_002986590.1 PFAM: major facilitator superfamily MFS_1; KEGG: plu:plu0937 hypothetical protein YP_002986591.1 PFAM: thymidylate kinase; KEGG: plu:plu0936 hypothetical protein YP_002986592.1 KEGG: plu:plu0935 hypothetical protein YP_002986593.1 PFAM: inositol monophosphatase; KEGG: plu:plu0934 hypothetical protein YP_002986594.1 KEGG: plu:plu0933 hypothetical protein YP_002986595.1 KEGG: plu:plu0932 hypothetical protein YP_002986597.1 PFAM: NUDIX hydrolase; KEGG: ara:Arad_8648 nucleoside polyphosphate hydrolase protein YP_002986598.1 PFAM: major facilitator superfamily MFS_1; KEGG: bsu:BSU27760 sigma-B-transcribed gene YP_002986599.1 KEGG: eca:ECA3560 oligogalacturonide transporter YP_002986600.1 PFAM: glycoside hydrolase family 28; SMART: Parallel beta-helix repeat; KEGG: eca:ECA3552 polygalacturonase YP_002986602.1 KEGG: eca:ECA3550 hypothetical protein YP_002986603.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002986604.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yen:YE1438 D-mannonate oxidoreductase YP_002986605.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA1092 GntR family transcriptional regulator YP_002986606.1 PFAM: peptidase U34 dipeptidase; KEGG: dal:Dalk_1471 peptidase U34 dipeptidase YP_002986607.1 PFAM: phosphatidylserine decarboxylase-related; KEGG: bxe:Bxe_C0076 phosphatidylserine decarboxylase YP_002986608.1 KEGG: bav:BAV3207 poly(aspartic acid) hydrolase YP_002986609.1 membrane component of a sugar ABC transporter system YP_002986610.1 PFAM: inner-membrane translocator; KEGG: eum:ECUMN_4763 sugar transporter subunit: membrane component of ABC superfamily YP_002986611.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: kpe:KPK_5042 sugar ABC transporter ATP-binding protein YP_002986612.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ecd:ECDH10B_4422 sugar ABC transporter periplasmic-binding protein YP_002986613.1 PFAM: PEBP family protein; KEGG: rfr:Rfer_3962 YbcL YP_002986614.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: spe:Spro_2944 AraC family transcriptional regulator YP_002986615.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbl:Sbal_1938 hypothetical protein YP_002986616.1 KEGG: rpi:Rpic_2604 hypothetical protein YP_002986618.1 TIGRFAM: acetoin reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ent:Ent638_2028 acetoin reductase YP_002986620.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eta:ETA_25920 lysine exporter protein (LysE/YggA) YP_002986621.1 PFAM: cytochrome B561; KEGG: eca:ECA0823 cytochrome b561 YP_002986622.1 PFAM: cyclase/dehydrase; KEGG: eca:ECA3372 hypothetical protein YP_002986623.1 PFAM: damage inducible protein CinA; KEGG: eca:ECA3370 competence damage-inducible protein A YP_002986624.1 KEGG: eca:ECA3369 recombinase A; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: ATPase AAA YP_002986625.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002986626.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002986627.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002986628.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_002986629.1 KEGG: eca:ECA3364 hypothetical protein YP_002986630.1 involved in the first step of glutathione biosynthesis YP_002986631.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002986632.1 KEGG: eca:ECA1162 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_002986633.1 KEGG: eca:ECA1163 lipoprotein YP_002986634.1 TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: yps:YPTB0977 6-O-methylguanine DNA methyltransferase family protein YP_002986635.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_002986636.1 KEGG: eca:ECA1166 hypothetical protein YP_002986637.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B YP_002986638.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: eca:ECA1170 acriflavine resistance protein A YP_002986639.1 PFAM: Tetracycline transcriptional repressor MAATS-type domain protein; regulatory protein TetR; KEGG: eca:ECA1171 DNA-binding transcriptional repressor AcrR YP_002986640.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_002986641.1 KEGG: eca:ECA1172 hypothetical protein YP_002986642.1 PFAM: Primosomal replication priB and priC; KEGG: eca:ECA1173 primosomal replication protein N'' YP_002986643.1 PFAM: tRNA-hydroxylase; KEGG: vfm:VFMJ11_1585 tRNA-hydroxylase YP_002986644.1 PFAM: protein of unknown function DUF454; KEGG: eca:ECA1174 hypothetical protein YP_002986645.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002986646.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002986647.1 PFAM: conserved hypothetical protein; KEGG: stt:t2375 hypothetical protein YP_002986648.1 KEGG: spe:Spro_1137 recombination protein RecR; TIGRFAM: recombination protein RecR; PFAM: TOPRIM domain protein; Zinc finger C4-type, RecR; SMART: Toprim sub domain protein YP_002986649.1 molecular chaperone YP_002986651.1 TIGRFAM: adenylate kinase; PFAM: adenylate kinase; adenylate kinase lid domain protein; KEGG: spe:Spro_1139 nucleoside-triphosphate--adenylate kinase YP_002986652.1 KEGG: eca:ECA1181 ferrochelatase; TIGRFAM: ferrochelatase; PFAM: ferrochelatase YP_002986653.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_002986654.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_002986655.1 PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; SMART: chemotaxis sensory transducer; KEGG: bac:BamMC406_6172 methyl-accepting chemotaxis sensory transducer YP_002986656.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: eca:ECA1191 hypothetical protein YP_002986657.1 KEGG: eca:ECA1192 hypothetical protein YP_002986658.1 TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA1193 copper exporting ATPase YP_002986659.1 KEGG: spe:Spro_1151 MerR family transcriptional regulator; TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR YP_002986660.1 PFAM: protein of unknown function DUF107; KEGG: eca:ECA1195 hypothetical protein YP_002986661.1 PFAM: band 7 protein; SMART: band 7 protein; KEGG: eca:ECA1196 hypothetical protein YP_002986662.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_002986663.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002986664.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002986665.1 KEGG: eca:ECA1200 3-demethylubiquinone-9 3-methyltransferase; TIGRFAM: ubiquinone biosynthesis O-methyltransferase; PFAM: methyltransferase type 11; methyltransferase type 12 YP_002986666.1 negatively supercoils closed circular double-stranded DNA YP_002986667.1 PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: eca:ECA1202 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_002986668.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_002986669.1 KEGG: eca:ECA1204 phosphotransfer intermediate protein in two-component regulatory system with RcsBC; PFAM: Hpt domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein YP_002986671.1 TIGRFAM: isochorismate synthase; PFAM: chorismate binding-like; KEGG: eca:ECA1210 menaquinone-specific isochorismate synthase YP_002986672.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002986673.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_002986674.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_002986675.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_002986676.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA1215 O-succinylbenzoic acid--CoA ligase YP_002986677.1 PFAM: YfaZ family protein; KEGG: eca:ECA1217 hypothetical protein YP_002986678.1 TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis protein; PFAM: molybdopterin binding domain; KEGG: eca:ECA1219 competence damage-inducible protein A YP_002986679.1 PFAM: thioredoxin domain; KEGG: eca:ECA1220 thioredoxin YP_002986680.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA1221 short chain dehydrogenase YP_002986681.1 PFAM: lipolytic protein G-D-S-L family; KEGG: ecq:ECED1_0521 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 YP_002986682.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: spe:Spro_1158 ABC transporter ATP-binding protein YbbA YP_002986683.1 PFAM: protein of unknown function DUF214; KEGG: eca:ECA1224 hypothetical protein YP_002986684.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: spe:Spro_1016 TonB-dependent siderophore receptor YP_002986685.1 PFAM: periplasmic binding protein; KEGG: yen:YE3190 hypothetical protein YP_002986686.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_002986687.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_002986688.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE2815 galactose-binding protein YP_002986689.1 negative regulator of the mglBAC operon for galactose utilization YP_002986690.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase; KEGG: ypg:YpAngola_A3119 phosphoribosylglycinamide formyltransferase YP_002986691.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002986692.1 KEGG: eca:ECA1255 uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_002986693.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: spe:Spro_3522 uracil transporter YP_002986694.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_002986695.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: spe:Spro_3518 arsenate reductase YP_002986696.1 PFAM: peptidase M48 Ste24p; KEGG: eca:ECA1259 hypothetical protein YP_002986697.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002986698.1 PFAM: amino acid-binding ACT domain protein; KEGG: eca:ECA1261 glycine cleavage system transcriptional repressor YP_002986699.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002986700.1 PFAM: NlpBDapX family lipoprotein; KEGG: eca:ECA1263 lipoprotein YP_002986701.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002986702.1 PFAM: protein of unknown function DUF441; KEGG: eca:ECA1265 hypothetical protein YP_002986703.1 PFAM: protein of unknown function DUF699 ATPase ; GCN5-related N-acetyltransferase; KEGG: eca:ECA1266 acetyltransferase YP_002986704.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002986705.1 KEGG: ypg:YpAngola_A3139 hypothetical protein YP_002986706.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: eca:ECA1290 D-alanyl-D-alanine carboxypeptidase YP_002986707.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002986708.1 PFAM: arsenate reductase; KEGG: esa:ESA_00779 hypothetical protein YP_002986709.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1293 aspartate/glutamate racemase YP_002986710.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: eta:ETA_23620 cold shock-like protein YP_002986711.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: eca:ECA1295 hypothetical protein YP_002986712.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: efe:EFER_2477 TatABCE protein translocation system subunit YP_002986713.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002986714.1 KEGG: eca:ECA1298 lipoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase YP_002986715.1 PFAM: protein of unknown function DUF493; KEGG: eca:ECA1299 hypothetical protein YP_002986716.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_002986717.1 TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; sporulation domain protein; KEGG: eca:ECA1301 lipoprotein A YP_002986718.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: eca:ECA1302 cell wall shape-determining protein YP_002986719.1 KEGG: eca:ECA1303 penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_002986720.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002986721.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: esa:ESA_02690 hypothetical protein YP_002986722.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002986723.1 required for the assembly and function of the DNAX complex which is required for the assembly of the subunit beta onto primed DNA YP_002986724.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_002986725.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002986726.1 PFAM: protein of unknown function DUF1451; KEGG: spe:Spro_1208 hypothetical protein YP_002986727.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: set:SEN0631 glutamate/aspartate transport ATP-binding protein GltL YP_002986728.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1312 glutamate/aspartate transporter permease protein YP_002986729.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1313 glutamate/aspartate transporter permease protein YP_002986730.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: spe:Spro_1214 glutamate and aspartate transporter subunit YP_002986731.1 transfers the fatty acyl group on membrane lipoproteins YP_002986732.1 PFAM: transporter-associated region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: eca:ECA1316 magnesium and cobalt efflux protein corc YP_002986733.1 PFAM: protein of unknown function UPF0054; KEGG: eca:ECA1317 metalloprotease YP_002986734.1 PFAM: PhoH family protein; KEGG: spe:Spro_1218 PhoH family protein YP_002986735.1 KEGG: eca:ECA1319 hypothetical protein; TIGRFAM: tRNA-i(6)A37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family; PFAM: protein of unknown function UPF0004 ; radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB YP_002986736.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_002986737.1 PFAM: small multidrug resistance protein; KEGG: ses:SARI_01331 hypothetical protein YP_002986738.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_002986739.1 PFAM: ROK family protein; KEGG: eca:ECA1324 N-acetylglucosamine repressor YP_002986740.1 KEGG: eca:ECA1325 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; amidohydrolase YP_002986741.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002986742.1 TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: eca:ECA1327 PTS system, N-acetylglucosamine-specific IIABC component YP_002986743.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002986744.1 PFAM: ferric-uptake regulator; KEGG: spe:Spro_1236 ferric uptake regulator YP_002986745.1 TIGRFAM: flavodoxin; PFAM: flavodoxin/nitric oxide synthase; KEGG: eca:ECA1330 flavodoxin FldA YP_002986746.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA1332 methyl-accepting chemotaxis protein YP_002986747.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: eca:ECA1333 LexA regulated protein YP_002986748.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: eca:ECA1334 hypothetical protein YP_002986749.1 PFAM: SeqA family protein; KEGG: eca:ECA1335 replication initiation regulator SeqA YP_002986750.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002986751.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA1337 hypothetical protein YP_002986752.1 KEGG: pau:PA14_64430 hypothetical protein YP_002986753.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_002986754.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_002986755.1 KEGG: eca:ECA1340 potassium-transporting ATPase C chain; TIGRFAM: potassium ABC transporter ATPase; PFAM: K transporting ATPase KdpC subunit YP_002986756.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002986757.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002986758.1 TIGRFAM: K+-transporting ATPase, F subunit YP_002986759.1 KEGG: eca:ECA1344 hypothetical protein YP_002986760.1 PFAM: protein of unknown function DUF1722; protein of unknown function DUF523; KEGG: eca:ECA1348 hypothetical protein YP_002986761.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_002986762.1 PFAM: protein of unknown function DUF34; KEGG: eca:ECA1350 hydrolase-oxidase YP_002986763.1 PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1; KEGG: eca:ECA1351 allophanate hydrolase subunit 1 YP_002986764.1 KEGG: eca:ECA1352 allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; SMART: allophanate hydrolase subunit 2 YP_002986765.1 PFAM: LamB/YcsF family protein; KEGG: yen:YE2953 hypothetical protein YP_002986766.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_002986767.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: eca:ECA1357 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002986768.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: eca:ECA1358 succinate dehydrogenase cytochrome b556 small membrane subunit YP_002986769.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002986770.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: yen:YE2945 succinate dehydrogenase iron-sulfur subunit YP_002986771.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002986772.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: eca:ECA1362 dihydrolipoamide acetyltransferase YP_002986773.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002986774.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002986775.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: eca:ECA1365 cytochrome d ubiquinol oxidase subunit I YP_002986776.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: eca:ECA1366 cytochrome d ubiquinol oxidase subunit II YP_002986777.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: eca:ECA1367 hypothetical protein YP_002986778.1 TIGRFAM: cyd operon protein YbgE; KEGG: eca:ECA1368 hypothetical protein YP_002986779.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_002986780.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002986781.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002986782.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_002986783.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002986784.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: yen:YE2931 peptidoglycan-associated outer membrane lipoprotein YP_002986785.1 TIGRFAM: tol-pal system protein YbgF; KEGG: yen:YE2930 hypothetical protein YP_002986786.1 PFAM: protein of unknown function DUF554; KEGG: eca:ECA1376 hypothetical protein YP_002986787.1 TIGRFAM: quinolinate synthetase complex, subunit alpha; PFAM: Quinolinate synthetase A; KEGG: eca:ECA1378 quinolinate synthetase YP_002986788.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: spe:Spro_1283 nicotinamide mononucleotide transporter PnuC YP_002986789.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002986790.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002986791.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1383 cation efflux system protein YP_002986792.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: eca:ECA1384 copper efflux system protein YP_002986793.1 PFAM: outer membrane efflux protein; KEGG: eca:ECA1385 hypothetical protein YP_002986794.1 KEGG: eca:ECA1386 hypothetical protein YP_002986795.1 KEGG: eca:ECA1387 hypothetical protein YP_002986796.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_002986797.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: yps:YPTB1169 galactokinase YP_002986798.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_002986799.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1389 UDP-galactose-4-epimerase YP_002986800.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_002986801.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_002986802.1 KEGG: kpn:KPN_00776 hypothetical protein YP_002986803.1 with ModCB is involved in the high-affinity transport of molybdate YP_002986804.1 TIGRFAM: molybdate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1394 molybdate ABC transporter permease YP_002986805.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002986806.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_002986807.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_002986808.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: esa:ESA_01898 hypothetical protein YP_002986809.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: pol:Bpro_4850 rhodanese-like YP_002986810.1 PFAM: ornithine cyclodeaminase/mu-crystallin; shikimate/quinate 5-dehydrogenase; KEGG: esa:ESA_01897 hypothetical protein YP_002986811.1 TIGRFAM: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: ade:Adeh_1432 D-cysteine desulfhydrase YP_002986812.1 PFAM: peptidase M20; KEGG: esa:ESA_01896 hypothetical protein YP_002986813.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: esa:ESA_01895 hypothetical protein YP_002986814.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: esa:ESA_01894 hypothetical protein YP_002986815.1 PFAM: extracellular solute-binding protein family 5; KEGG: esa:ESA_01893 hypothetical protein YP_002986816.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: esa:ESA_01892 hypothetical protein YP_002986818.1 KEGG: eca:ECA1404 hypothetical protein YP_002986819.1 KEGG: eca:ECA1405 hypothetical protein YP_002986820.1 PFAM: VirK family protein; KEGG: xac:XAC0435 VirK protein YP_002986821.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002986822.1 KEGG: eca:ECA1410 ATPase YP_002986823.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002986824.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002986825.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_002986826.1 PFAM: integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA1415 hypothetical protein YP_002986827.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: aha:AHA_2881 nucleotide sugar epimerase YP_002986828.1 KEGG: ent:Ent638_2641 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase ; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_002986829.1 PFAM: nucleotidyl transferase; KEGG: eca:ECA1443 UTP--glucose-1-phosphate uridylyltransferase YP_002986830.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002986831.1 KEGG: eca:ECA1453 signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE2 domain protein; SMART: GGDEF domain containing protein YP_002986832.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA1505 hypothetical protein YP_002986834.1 PFAM: protein of unknown function DUF535; KEGG: eta:ETA_30810 virulence protein YP_002986835.1 PFAM: Haemin-degrading family protein; KEGG: yps:YPTB0339 hemin degradation/transporter HmuS YP_002986836.1 PFAM: periplasmic binding protein; KEGG: sgl:SG1538 hemin ABC transporter periplasmic component YP_002986837.1 PFAM: transporter permease; KEGG: sgl:SG1539 hemin ABC transporter permease YP_002986838.1 with HmuTU is involved in the transport of hemin YP_002986839.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: kpe:KPK_1035 TonB-dependent receptor YP_002986840.1 PFAM: ferritin; KEGG: spe:Spro_2688 ferritin Dps family protein YP_002986841.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002986842.1 KEGG: eta:ETA_22260 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_002986844.1 PFAM: aminotransferase class IV; KEGG: eca:ECA3117 D-alanine aminotransferase YP_002986845.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA3116 mandelate racemase/muconate lactonizing enzyme YP_002986846.1 PFAM: protein of unknown function DUF1611; KEGG: mes:Meso_0034 protein of unknown function DUF1611 YP_002986847.1 KEGG: eca:ECA3148 regulator; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_002986848.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: pat:Patl_2326 IclR family transcriptional regulator YP_002986849.1 PFAM: aldehyde dehydrogenase; KEGG: ara:Arad_7566 aldehyde dehydrogenase protein YP_002986850.1 KEGG: aci:ACIAD2279 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE2 domain protein; SMART: GGDEF domain containing protein YP_002986851.1 KEGG: pha:PSHAa1169 GGDEF protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Two component regulator propeller; Two component regulator three Y domain protein; SMART: GGDEF domain containing protein YP_002986852.1 KEGG: apj:APJL_1697 gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_002986853.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002986854.1 KEGG: eca:ECA2840 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_002986855.1 PFAM: major facilitator superfamily MFS_1; KEGG: ppw:PputW619_2449 major facilitator transporter YP_002986856.1 PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: stm:STM1795 glutamic dehyrogenase-like protein YP_002986857.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aav:Aave_0204 LysR family transcriptional regulator YP_002986858.1 PFAM: protein of unknown function DUF162; KEGG: eca:ECA1918 hypothetical protein YP_002986859.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: cko:CKO_04246 hypothetical protein YP_002986860.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: eca:ECA1920 hypothetical protein YP_002986861.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bxe:Bxe_A1171 AraC family transcriptional regulator YP_002986862.1 PFAM: LrgB family protein; KEGG: ent:Ent638_2745 hypothetical protein YP_002986863.1 PFAM: LrgA family protein; KEGG: ses:SARI_00720 hypothetical protein YP_002986864.1 PFAM: copper resistance protein CopC; KEGG: esa:ESA_01399 hypothetical protein YP_002986865.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_2901 malonate utilization transcriptional regulator MdcR YP_002986866.1 TIGRFAM: malonate decarboxylase, subunit epsilon; PFAM: acyl transferase; KEGG: kpn:KPN_01558 acyl carrier protein S-malonyltransferase YP_002986867.1 Catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein YP_002986868.1 TIGRFAM: auxin efflux carrier; PFAM: Auxin Efflux Carrier; KEGG: cko:CKO_04764 hypothetical protein YP_002986869.1 TIGRFAM: malonate decarboxylase, subunit gamma; PFAM: malonate decarboxylase subunit gamma; KEGG: kpn:KPN_01560 acetyl-CoA carboxylase subunit alpha YP_002986870.1 The subunit beta catalyzes the decarboxylation of the malonyl moiety on coenzyme A YP_002986871.1 TIGRFAM: malonate decarboxylase acyl carrier protein; PFAM: malonate decarboxylase subunit delta; KEGG: kpe:KPK_2896 malonate decarboxylase, subunit delta YP_002986872.1 KEGG: kpe:KPK_2895 triphosphoribosyl-dephospho-CoA synthase MdcB; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase MdcB; PFAM: triphosphoribosyl-dephospho-CoA protein YP_002986873.1 TIGRFAM: malonate decarboxylase, subunit alpha; KEGG: ses:SARI_04157 hypothetical protein YP_002986874.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: bid:Bind_0037 short-chain dehydrogenase/reductase SDR YP_002986875.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_0040 short-chain dehydrogenase/reductase SDR YP_002986876.1 PFAM: patatin; KEGG: pol:Bpro_3091 patatin YP_002986877.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: rme:Rmet_4289 nucleoside-diphosphate-sugar epimerase YP_002986878.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: xac:XAC0536 virulence regulating protein YP_002986879.1 PFAM: Post-segregation antitoxin CcdA; KEGG: spe:Spro_1554 post-segregation antitoxin CcdA YP_002986880.1 KEGG: bpt:Bpet1373 phosphoserine phosphatase YP_002986881.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: bpt:Bpet1372 amino acid efflux transmembrane protein YP_002986882.1 KEGG: bpt:Bpet1371 hypothetical protein YP_002986883.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bpt:Bpet1370 LysR family transcriptional regulator YP_002986885.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_002986886.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_002986887.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1500 aspartate racemase YP_002986888.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1501 LysR family transcriptional regulator YP_002986889.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA1503 proton glutamate symport protein YP_002986890.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; GAF domain protein; KEGG: yen:YE2811 hydrogenlyase transcriptional activator YP_002986891.1 PFAM: protein of unknown function DUF1272; KEGG: dac:Daci_2219 hypothetical protein YP_002986892.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: yen:YE2810 formate dehydrogenase H YP_002986893.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yen:YE2809 4Fe-4S ferrodoxin YP_002986895.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA2115 transcriptional regulator YP_002986896.1 PFAM: aminotransferase class-III; KEGG: eca:ECA2060 class-III aminotransferase YP_002986897.1 PFAM: aminoglycoside phosphotransferase; KEGG: eca:ECA2059 phosphotransferase YP_002986898.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA2058 short-chain dehydrogenase YP_002986899.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2055 transporter, periplasmic solute-binding protein YP_002986900.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_002986901.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: yen:YE2807 hydrogenase-4 component J YP_002986902.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: yen:YE2806 hydrogenase-4 component I YP_002986903.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_002986904.1 PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: yen:YE2804 hydrogenase-4 component G YP_002986905.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: yen:YE2803 hydrogenase 4 subunit F YP_002986906.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_002986907.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: yen:YE2801 hydrogenase 4 subunit D YP_002986908.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: yen:YE2800 hydrogenase-4 component C YP_002986909.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: yen:YE2799 hydrogenase 4 subunit B YP_002986910.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yen:YE2798 hydrogenase-4 component A YP_002986911.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: yen:YE2796 hydrogenase isoenzymes formation protein YP_002986912.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: spe:Spro_2538 hypothetical protein YP_002986913.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1519 transcriptional regulator CysB-like protein YP_002986914.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA1520 glutamate/aspartate:proton symporter YP_002986915.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bav:BAV1173 AraC-family transcriptional regulator YP_002986916.1 PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: bav:BAV1174 2-isopropylmalate synthase YP_002986917.1 PFAM: protein of unknown function UPF0153; KEGG: scl:sce4748 hypothetical protein YP_002986918.1 KEGG: xac:XAC0538 hypothetical protein YP_002986919.1 PFAM: protein of unknown function DUF218; KEGG: eum:ECUMN_1662 hypothetical protein YP_002986920.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: eca:ECA1523 glycerol dehydrogenase YP_002986921.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1524 ABC transporter permease YP_002986922.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1525 ABC transporter ATP-binding protein YP_002986923.1 KEGG: eca:ECA1526 ABC transporter periplasmic protein YP_002986924.1 PFAM: malate/L-lactate dehydrogenase; KEGG: eca:ECA1527 malate/lactate dehydrogenase YP_002986925.1 catalyzes the formation of pyruvate from D-cysteine YP_002986926.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1532 aspartate racemase YP_002986927.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_002986928.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_002986930.1 KEGG: sml:Smlt1844 modification methylase YP_002986931.1 may be involved in phosphonate uptake and biodegradation YP_002986932.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: spe:Spro_0521 phosphonate metabolism PhnG YP_002986933.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: ypg:YpAngola_A4030 carbon-phosphorus lyase complex subunit YP_002986934.1 PFAM: phosphonate metabolism; KEGG: spe:Spro_0519 phosphonate metabolism YP_002986935.1 PFAM: phosphonate metabolism PhnJ; KEGG: yps:YPTB0513 protein in phn operon YP_002986936.1 KEGG: yen:YE0473 phosphonates transport ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: ATPase AAA YP_002986937.1 KEGG: ypg:YpAngola_A4026 phosphonate ABC transporter ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter; SMART: ATPase AAA YP_002986938.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; amidohydrolase; KEGG: spe:Spro_0515 phosphonate metabolism protein PhnM YP_002986939.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: yen:YE0470 ribose 1,5-bisphosphokinase YP_002986940.1 TIGRFAM: phosphonate metabolism protein PhnP; PFAM: beta-lactamase; KEGG: spe:Spro_0512 carbon-phosphorus lyase complex accessory protein YP_002986941.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rle:RL2486 LysR family transcriptional regulator YP_002986942.1 PFAM: major facilitator superfamily MFS_1; KEGG: pna:Pnap_1660 major facilitator superfamily transporter YP_002986943.1 KEGG: spe:Spro_1410 phosphonate ABC transporter ATPase subunit; TIGRFAM: phosphonate ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_002986944.1 TIGRFAM: phosphonate ABC transporter periplasmic phosphonate binding protein; phosphonate ABC transporter periplasmic phosphonate-binding protein; KEGG: spe:Spro_1411 phosphonate ABC transporter periplasmic phosphonate-binding protein YP_002986945.1 TIGRFAM: phosphonate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_1412 phosphonate ABC transporter inner membrane subunit YP_002986946.1 TIGRFAM: phosphonate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_1413 phosphonate ABC transporter inner membrane subunit YP_002986947.1 PFAM: ABC transporter; KEGG: psp:PSPPH_2760 achromobactin transport ATP-binding protein CbrD YP_002986948.1 PFAM: protein of unknown function UPF0150; KEGG: hsm:HSM_0889 hypothetical protein YP_002986949.1 PFAM: YcfA family protein; KEGG: bte:BTH_II1999 hypothetical protein YP_002986950.1 KEGG: ecw:EcE24377A_1771 hypothetical protein YP_002986951.1 KEGG: bba:Bd0901 Zn-dependent hydrolase YP_002986953.1 PFAM: dihydrodipicolinate synthetase; KEGG: smd:Smed_4167 dihydrodipicolinate synthetase YP_002986954.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_002986955.1 PFAM: glycoside hydrolase clan GH-D; KEGG: esa:ESA_03854 hypothetical protein YP_002986956.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: ent:Ent638_4078 LacI family transcription regulator YP_002986957.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_002986958.1 TIGRFAM: formate dehydrogenase subunit beta; PFAM: formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA1407 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_002986959.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: eca:ECA1408 formate dehydrogenase, nitrate-inducible, major subunit YP_002986960.1 PFAM: peptidase C1A papain; SMART: peptidase C1A papain; KEGG: xft:PD0125 cysteine protease YP_002986961.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eta:ETA_13850 GCN5-related N-acetyltransferase YP_002986962.1 KEGG: ent:Ent638_2009 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_002986963.1 KEGG: spe:Spro_1006 periplasmic ligand-binding sensor protein YP_002986964.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: kpn:KPN_01655 2OG-Fe(II) oxygenase YP_002986965.1 PFAM: NLPA lipoprotein; KEGG: yen:YE1466 hypothetical protein YP_002986966.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: esa:ESA_02818 hypothetical protein YP_002986967.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpe:KPK_2723 methionine uptake ABC transporter (MUT) family, permease YP_002986968.1 PFAM: ROK family protein; KEGG: avi:Avi_5249 transcriptional regulator ROK family YP_002986969.1 PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_1296 multiple sugar transporter substrate-binding protein YP_002986970.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: avi:Avi_5252 ABC transporter membrane spanning protein (sugar) YP_002986971.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: avi:Avi_5253 ABC transporter membrane spanning protein (sugars) YP_002986972.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: avi:Avi_5254 ABC transporter nucleotide binding/ATPase protein (sugar) YP_002986973.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: mlo:mll3063 hypothetical protein YP_002986974.1 KEGG: hypothetical protein YP_002986975.1 PFAM: thioredoxin domain; KEGG: eca:ECA1555 hypothetical protein YP_002986976.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1556 sulfate ester transporter ATP-binding component YP_002986977.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1557 sulfate ester transporter permease YP_002986978.1 KEGG: eca:ECA1558 sulfate ester transporter periplasmic binding component YP_002986979.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1559 LysR family transcriptional regulator YP_002986980.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: eca:ECA1560 CDP-diacylglycerol pyrophosphatase YP_002986981.1 KEGG: hypothetical protein YP_002986982.1 KEGG: sbm:Shew185_1326 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; hypothetical protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein YP_002986983.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: kpe:KPK_1612 inorganic anion transporter sulfate permease (SulP) family YP_002986984.1 PFAM: amidohydrolase; KEGG: spe:Spro_1116 adenine deaminase YP_002986985.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: spe:Spro_1117 LysR family transcriptional regulator YP_002986986.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: hch:HCH_03207 catalase/peroxidase HPI YP_002986987.1 PFAM: sigma-54 factor interaction domain-containing protein; SMART: ATPase AAA; KEGG: dal:Dalk_1286 PAS modulated sigma54 specific Fis family transcriptional regulator YP_002986988.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0912 hypothetical protein YP_002986989.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; FAD dependent oxidoreductase; HI0933 family protein; KEGG: eca:ECA0910 flavoprotein subunit of a reductase YP_002986990.1 PFAM: carbohydrate-selective porin OprB; KEGG: mch:Mchl_1436 carbohydrate-selective porin OprB YP_002986991.1 PFAM: polysulphide reductase NrfD; KEGG: eca:ECA0913 component of polysulfide reductase YP_002986992.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA0914 component of polysulfide reductase YP_002986993.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rpc:RPC_0633 LysR family transcriptional regulator YP_002986994.1 PFAM: enoyl-CoA hydratase/isomerase; KEGG: rpc:RPC_0631 enoyl-CoA hydratase/isomerase YP_002986996.1 PFAM: protein of unknown function DUF849; KEGG: rpc:RPC_0635 hypothetical protein YP_002986997.1 KEGG: rpc:RPC_0636 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase YP_002986998.1 KEGG: rpc:RPC_0637 3-oxoacid CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; PFAM: coenzyme A transferase YP_002986999.1 PFAM: coenzyme A transferase; KEGG: rpc:RPC_0638 3-oxoacid CoA-transferase YP_002987000.1 PFAM: major facilitator superfamily MFS_1; KEGG: rpc:RPC_0639 major facilitator transporter YP_002987001.1 KEGG: rpc:RPC_0632 MetA-pathway phenol degradation-like protein YP_002987002.1 KEGG: cko:CKO_00545 hypothetical protein; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase YP_002987003.1 PFAM: PfkB domain protein; KEGG: sus:acid_2122 ribokinase-like domain-containing protein YP_002987004.1 PFAM: Domain of unknown function DUF1870; KEGG: ecz:ECS88_1739 hypothetical protein YP_002987005.1 PFAM: shikimate kinase; KEGG: efe:EFER_2635 shikimate kinase II (SKII) YP_002987006.1 PFAM: major facilitator superfamily MFS_1; KEGG: sew:SeSA_A1457 inner membrane transporter YdiM YP_002987007.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_4670 LysR family transcriptional regulator YP_002987008.1 PFAM: major facilitator superfamily MFS_1; KEGG: ecv:APECO1_767 predicted transporter YP_002987009.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_002987010.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_002987011.1 PFAM: coenzyme A transferase; KEGG: elf:LF82_2872 uncharacterized protein YdiF YP_002987012.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002987013.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA2295 AraC family transcription regulator YP_002987014.1 PFAM: chitin synthase; KEGG: eca:ECA2046 bifunctional enzyme including aminotransferase and chitin synthase YP_002987015.1 PFAM: outer membrane porin; KEGG: yen:YE2976 hypothetical protein YP_002987017.1 PFAM: cupin; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ecz:ECS88_1746 DNA-binding transcriptional regulator YP_002987019.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002987020.1 May play a role in a redox process YP_002987021.1 PFAM: FAD dependent oxidoreductase; monooxygenase FAD-binding; HI0933 family protein; KEGG: ecq:ECED1_1901 oxidoreductase subunit with FAD/NAD(P)-binding domain YP_002987022.1 KEGG: set:SEN1693 ferredoxin YP_002987023.1 acts in anaerobic beta-oxidation of fatty acids; ligase/synthase involved in anaerobic growth on fatty acids YP_002987024.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pna:Pnap_2708 AraC family transcriptional regulator YP_002987025.1 PFAM: major facilitator superfamily MFS_1; KEGG: see:SNSL254_A1655 membrane transporter YP_002987026.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: cak:Caul_0413 acyl-CoA dehydrogenase domain-containing protein YP_002987027.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002987028.1 PFAM: Desulfoferrodoxin ferrous iron-binding region; KEGG: dat:HRM2_42000 Dfx YP_002987029.1 TIGRFAM: PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose subfamily, IIsubunit alpha; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: eca:ECA0661 PTS system, beta-glucoside-specific IIABC component YP_002987030.1 PFAM: PRD domain protein; CAT RNA-binding domain protein; KEGG: eca:ECA1452 beta-glucoside operon antiterminator YP_002987031.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA0662 6-phospho-beta-glucosidase YP_002987032.1 PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: yen:YE3022 hypothetical protein YP_002987033.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: plu:plu0977 hypothetical protein YP_002987034.1 KEGG: acr:Acry_3004 3-oxoadipate enol-lactonase YP_002987035.1 KEGG: eca:ECA2978 hypothetical protein YP_002987036.1 PFAM: beta-lactamase; KEGG: gbe:GbCGDNIH1_1166 metal-dependent hydrolase YP_002987037.1 PFAM: regulatory protein LysR; KEGG: avi:Avi_0554 transcriptional regulator LysR family YP_002987038.1 KEGG: eca:ECA3122 type I restriction enzyme EcoEI R protein YP_002987039.1 KEGG: plu:plu3832 hypothetical protein YP_002987040.1 involved in polyketide production YP_002987041.1 involved in polyketide synthesis YP_002987042.1 PFAM: hydroxymethylglutaryl-coenzyme A synthase domain protein; hydroxymethylglutaryl-coenzyme A synthase domain; KEGG: bte:BTH_II1670 polyketide biosynthesis protein YP_002987043.1 involved in polyketide production YP_002987044.1 KEGG: bmn:BMA10247_A1115 acyl carrier protein YP_002987045.1 TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; methyltransferase FkbM family; PFAM: beta-ketoacyl synthase ; enoyl-CoA hydratase/isomerase; phosphopantetheine-binding; KEGG: scl:sce3188 polyketide synthase YP_002987046.1 PFAM: flavin-containing monooxygenase FMO; KEGG: bte:BTH_II2346 monooxygenase flavin-binding family protein YP_002987047.1 PFAM: beta-ketoacyl synthase ; KR domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: bsu:BSU17190 polyketide synthase of type I YP_002987048.1 PFAM: Luciferase-like monooxygenase; KEGG: mxa:MXAN_3937 luciferase-like monooxygenase family protein YP_002987049.1 PFAM: KR domain protein; beta-ketoacyl synthase ; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: bsu:BSU17180 polyketide synthase of type I YP_002987050.1 KEGG: bsu:BSU17180 polyketide synthase of type I YP_002987051.1 KEGG: nmu:Nmul_A0140 hypothetical protein YP_002987053.1 PFAM: beta-ketoacyl synthase ; KR domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3933 mixed type I polyketide synthase - peptide synthetase YP_002987054.1 PFAM: KR domain protein; beta-ketoacyl synthase ; methyltransferase type 11; methyltransferase type 12; short-chain dehydrogenase/reductase SDR; condensation domain protein; thioesterase; phosphopantetheine-binding; KEGG: bsu:BSU17200 polyketide synthase YP_002987056.1 TIGRFAM: PfaD family protein; CRISPR-associated protein DxTHG motif; KEGG: bsu:BSU17120 involved in polyketide synthesis YP_002987057.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: gur:Gura_3105 malonyl CoA-acyl carrier protein transacylase YP_002987058.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: bpd:BURPS668_A1475 malonyl CoA-acyl carrier protein transacylase YP_002987059.1 KEGG: spe:Spro_2323 PTS system, beta-glucoside-specific IIABC subunit YP_002987062.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA4427 LysR family transcriptional regulator YP_002987063.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4426 extracellular solute-binding protein YP_002987064.1 PFAM: dihydrodipicolinate synthetase; KEGG: eca:ECA4425 dihydrodipicolinate synthetase YP_002987065.1 PFAM: inosine/uridine-preferring nucleoside hydrolase; KEGG: eca:ECA4424 nucleoside hydrolase protein YP_002987066.1 PFAM: inosine/uridine-preferring nucleoside hydrolase; KEGG: eca:ECA4423 nucleoside hydrolase YP_002987067.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4422 ABC transporter permease YP_002987068.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4421 ABC transporter permease YP_002987069.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: eca:ECA4420 ABC transporter ATP-binding protein YP_002987070.1 PFAM: regulatory protein LysR; KEGG: eca:ECA2888 nitrogen assimilation regulatory protein (partial) YP_002987071.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA2885 D-alanine/D-serine/glycine permease YP_002987072.1 KEGG: eca:ECA2883 hypothetical protein YP_002987073.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002987074.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002987075.1 KEGG: spe:Spro_1850 phosphatidylglycerophosphate synthetase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_002987076.1 PFAM: regulatory protein TetR; KEGG: cps:CPS_4004 TetR family transcriptional regulator YP_002987077.1 KEGG: scl:sce4419 transcription negative regulator ChrR YP_002987078.1 PFAM: aconitate hydratase domain protein; KEGG: bph:Bphy_6199 3-isopropylmalate dehydratase YP_002987079.1 KEGG: psp:PSPPH_4996 hypothetical protein YP_002987080.1 PFAM: aminotransferase class I and II; KEGG: Os01g0871300; hypothetical protein YP_002987081.1 KEGG: bcj:BCAM0066 lipoprotein YP_002987082.1 PFAM: isochorismatase hydrolase; KEGG: cvi:CV_0540 hypothetical protein YP_002987083.1 PFAM: major facilitator superfamily MFS_1; KEGG: bpy:Bphyt_0628 major facilitator superfamily MFS_1 YP_002987084.1 PFAM: PilT protein domain protein; KEGG: eca:ECA2850 plasmid protein YP_002987085.1 KEGG: eca:ECA2851 plasmid protein YP_002987087.1 PFAM: aminotransferase class IV; KEGG: eca:ECA3117 D-alanine aminotransferase YP_002987088.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA3115 aminotransferase YP_002987089.1 TIGRFAM: lipoprotein, PulS/OutS family; KEGG: eca:ECA3114 general secretion pathway lipoprotein YP_002987090.1 KEGG: eca:ECA3113 general secretion pathway protein YP_002987091.1 TIGRFAM: general secretion pathway protein C; KEGG: eca:ECA3110 general secretion pathway protein C YP_002987092.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: kpe:KPK_4576 pullulanase secretion envelope protein PulD YP_002987093.1 KEGG: eca:ECA3108 general secretion pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: ATPase AAA YP_002987094.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: eca:ECA3107 general secretion pathway protein F YP_002987095.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: eca:ECA3106 general secretion pathway protein G YP_002987096.1 TIGRFAM: general secretion pathway protein H; KEGG: eca:ECA3105 general secretion pathway protein H YP_002987097.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: eca:ECA3104 general secretion pathway protein I YP_002987098.1 TIGRFAM: general secretion pathway protein J; KEGG: eca:ECA3103 general secretion pathway protein J YP_002987099.1 PFAM: general secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K YP_002987100.1 TIGRFAM: general secretion pathway protein L; PFAM: general secretion pathway L; KEGG: eca:ECA3101 general secretion pathway protein L YP_002987101.1 PFAM: general secretion pathway M protein; KEGG: eca:ECA3100 general secretion pathway protein M YP_002987102.1 PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: eca:ECA3098 type 4 prepilin-like proteins leader peptide processing enzyme YP_002987103.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3096 ABC-transporter periplasmic-binding component YP_002987104.1 PFAM: transporter permease; KEGG: eca:ECA3095 ABC transporter permease YP_002987105.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3094 ABC transporter ATP-binding protein YP_002987106.1 KEGG: eca:ECA3093 hypothetical protein YP_002987107.1 PFAM: protein of unknown function DUF1234; KEGG: eca:ECA3091 hypothetical protein YP_002987108.1 PFAM: thioesterase superfamily protein; KEGG: plu:plu2625 hypothetical protein YP_002987109.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_002987110.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: spe:Spro_3419 isochorismatase YP_002987111.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_002987112.1 TIGRFAM: isochorismate synthase; PFAM: chorismate binding-like; KEGG: spe:Spro_3421 isochorismate synthase YP_002987113.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cko:CKO_02589 hypothetical protein YP_002987114.1 PFAM: esterase; KEGG: yen:YE3622 enterobactin/ferric enterobactin esterase YP_002987115.1 PFAM: MbtH domain protein; KEGG: cvi:CV_2232 MbtH-like protein YP_002987116.1 TIGRFAM: amino acid adenylation protein; non-ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: cvi:CV_2233 synthetase CbsF YP_002987117.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: yen:YE3621 iron-siderophore transporter, ATP-binding component YP_002987118.1 PFAM: transporter permease; KEGG: yen:YE3620 iron-enterobactin transporter permease YP_002987119.1 PFAM: transporter permease; KEGG: yen:YE3619 iron-enterobactin transporter membrane protein YP_002987120.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_002987121.1 with FepCDG is involved in the transport of ferric enterobactin YP_002987123.1 TIGRFAM: 5'-nucleotidase, lipoprotein e(P4) family; PFAM: acid phosphatase (class B); KEGG: spe:Spro_1456 5'-nucleotidase YP_002987124.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_002987125.1 PFAM: cytochrome b562; KEGG: eca:ECA2222 soluble cytochrome b562 YP_002987126.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: eca:ECA2762 hypothetical protein YP_002987128.1 KEGG: sgl:SG1238 hypothetical protein YP_002987129.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1683 methyl-accepting chemotaxis protein YP_002987130.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_002987131.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002987132.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002987133.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002987134.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_002987135.1 PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: eca:ECA1690 purine-binding chemotaxis protein YP_002987136.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: eca:ECA1691 methyl-accepting chemotaxis protein YP_002987137.1 methylates the MCP YP_002987138.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002987139.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA1694 chemotaxis regulatory protein CheY YP_002987140.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_002987141.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002987142.1 membrane protein involved in the flagellar export apparatus YP_002987143.1 PFAM: flagellar FlhE family protein; KEGG: efe:EFER_1196 hypothetical protein YP_002987144.1 PFAM: FlgN family protein; KEGG: eca:ECA1699 flagella synthesis protein YP_002987145.1 PFAM: anti-sigma-28 factor FlgM family protein; KEGG: eca:ECA1700 anti-sigma28 factor FlgM YP_002987146.1 TIGRFAM: flagella basal body P-ring formation protein FlgA; PFAM: SAF domain protein; KEGG: yen:YE2561 flagellar basal body P-ring biosynthesis protein FlgA YP_002987147.1 TIGRFAM: flagellar basal-body rod protein FlgB; PFAM: flagellar basal body rod protein; KEGG: eca:ECA1702 flagellar basal body rod protein FlgB YP_002987148.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: ypy:YPK_2424 flagellar basal-body rod protein FlgC YP_002987149.1 PFAM: flagellar hook capping protein; KEGG: eta:ETA_20390 flagellar biosynthesis, initiation of hook assembly YP_002987150.1 the hook connects flagellar basal body to the flagellar filament YP_002987151.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: spe:Spro_2966 flagellar basal body rod protein FlgF YP_002987152.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: spe:Spro_2965 flagellar basal body rod protein FlgG YP_002987153.1 PFAM: flagellar L-ring protein; KEGG: eca:ECA1708 flagellar basal body L-ring protein YP_002987154.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_002987155.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002987156.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: yen:YE2551 flagellar hook-associated protein FlgK YP_002987157.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: yen:YE2550 flagellar hook-associated protein FlgL YP_002987158.1 PFAM: flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook-associated protein 2 domain protein; KEGG: eck:EC55989_2145 flagellar hook-associated protein 2 (HAP2) (filament cap protein) (flagellar cap protein) YP_002987159.1 TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; KEGG: stt:t0916 flagellar protein FliS YP_002987160.1 PFAM: flagellar export chaperone; KEGG: ypi:YpsIP31758_2285 flagellar biosynthesis protein FliT YP_002987161.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: eca:ECA1727 flagellar hook-basal body protein FliE YP_002987162.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_002987163.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002987164.1 PFAM: flagellar assembly protein FliH; KEGG: eca:ECA1724 flagellar assembly protein H YP_002987165.1 KEGG: eca:ECA1723 flagellum-specific ATP synthase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; SMART: ATPase AAA YP_002987166.1 TIGRFAM: flagellar export protein FliJ; PFAM: flagellar FliJ protein; KEGG: eca:ECA1722 flagellar biosynthesis chaperone YP_002987167.1 PFAM: flagellar hook-length control protein; KEGG: yen:YE2542 flagellar hook-length control protein FliK YP_002987168.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002987169.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002987170.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: eca:ECA1718 flagellar motor switch protein FliN YP_002987171.1 PFAM: flagellar biosynthesis protein FliO; KEGG: eca:ECA1717 flagellar protein YP_002987172.1 TIGRFAM: flagellar biosynthetic protein FliP; PFAM: type III secretion system inner membrane P protein; KEGG: eca:ECA1716 flagellar biosynthesis protein FliP YP_002987173.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: yen:YE2548 flagellar biosynthesis protein FliQ YP_002987175.1 PFAM: flagellin domain protein; KEGG: rme:Rmet_5252 flagellin YP_002987176.1 PFAM: glycosyl transferase family 2; KEGG: xcb:XC_2258 O-antigen biosynthesis protein YP_002987177.1 KEGG: bcj:BCAL3235 UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like YP_002987178.1 KEGG: bmj:BMULJ_02294 hypothetical protein YP_002987179.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002987180.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_002987181.1 PFAM: PhoH family protein; KEGG: eca:ECA1741 hypothetical protein YP_002987182.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: esa:ESA_pESA3p05527 hypothetical protein YP_002987183.1 PFAM: ribose/galactose isomerase; KEGG: eca:ECA1742 hypothetical protein YP_002987184.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_002987185.1 PFAM: peptidase S16; KEGG: eca:ECA1749 hypothetical protein YP_002987186.1 PFAM: protein of unknown function DUF1047; KEGG: eca:ECA1750 hypothetical protein YP_002987187.1 KEGG: eca:ECA1771 hypothetical protein YP_002987188.1 KEGG: eca:ECA1773 hypothetical protein YP_002987190.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1774 methyl-accepting chemotaxis protein YP_002987191.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_002987192.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_002987193.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: eca:ECA1779 lipid A biosynthesis lauroyl acyltransferase YP_002987194.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: eca:ECA1780 NADH-dependent flavin oxidoreductase YP_002987195.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: eca:ECA1781 hypothetical protein YP_002987196.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_002987197.1 PFAM: DinI family protein; KEGG: esa:ESA_02287 hypothetical protein YP_002987198.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002987199.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: eca:ECA1788 hypothetical protein YP_002987200.1 KEGG: yen:YE1627 ribonuclease E; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein YP_002987201.1 KEGG: eca:ECA1790 23S rRNA pseudouridylate synthase C; TIGRFAM: pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein YP_002987202.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: eca:ECA1791 Maf-like protein YP_002987203.1 PFAM: protein of unknown function DUF177; KEGG: eca:ECA1792 hypothetical protein YP_002987204.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002987205.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002987206.1 KEGG: eca:ECA1795 3-oxoacyl-(acyl carrier protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; hydroxymethylglutaryl-coenzyme A synthase domain YP_002987207.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: eca:ECA1796 acyl carrier protein S-malonyltransferase YP_002987208.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA1797 3-ketoacyl-(acyl-carrier-protein) reductase YP_002987209.1 carries the fatty acid chain in fatty acid biosynthesis YP_002987210.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002987211.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002987212.1 PFAM: aminodeoxychorismate lyase; KEGG: eca:ECA1801 aminodeoxychorismate lyase YP_002987213.1 KEGG: ypi:YpsIP31758_1583 thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: thymidylate kinase YP_002987214.1 KEGG: eca:ECA1803 DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III delta prime subunit; PFAM: DNA polymerase III subunit delta YP_002987215.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: eca:ECA1804 metallodependent hydrolase YP_002987216.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002987217.1 PFAM: regulatory protein TetR; KEGG: bxe:Bxe_A4300 TetR family transcriptional regulator YP_002987218.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rso:RS05496 oxidoreductase protein YP_002987219.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pen:PSEEN1512 short chain dehydrogenase YP_002987220.1 PFAM: malate/L-lactate dehydrogenase; KEGG: lhk:LHK_00733 malate/L-lactate dehydrogenase YP_002987221.1 PFAM: histidine triad (HIT) protein; KEGG: eca:ECA1809 purine nucleoside phosphoramidase YP_002987222.1 PFAM: protein of unknown function DUF1425; KEGG: eca:ECA1810 lipoprotein YP_002987223.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: eca:ECA1811 lipoprotein YP_002987224.1 PFAM: aminoglycoside phosphotransferase; KEGG: yps:YPTB2450 hypothetical protein YP_002987225.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002987226.1 PFAM: protein of unknown function UPF0227; KEGG: esa:ESA_02236 hypothetical protein YP_002987227.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA1815 NADH dehydrogenase YP_002987228.1 PFAM: 17 kDa surface antigen; KEGG: eca:ECA1816 hypothetical protein YP_002987229.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; KEGG: eca:ECA1966 transcriptional repressor YP_002987230.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1967 hexuronate transporter YP_002987231.1 PFAM: glycoside hydrolase family 31; KEGG: eca:ECA1968 glycosyl hydrolase YP_002987232.1 PFAM: N-acetyltransferase; KEGG: spe:Spro_1338 N-acetyltransferase YP_002987233.1 KEGG: eca:ECA1820 chaperone YP_002987234.1 PFAM: protein of unknown function DUF437; KEGG: vha:VIBHAR_06553 hypothetical protein YP_002987235.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: aha:AHA_3485 EAL domain-containing protein YP_002987236.1 KEGG: eca:ECA1821 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: TRCF domain protein; transcription factor CarD; helicase; DEAD/DEAH box helicase; type III restriction protein res subunit; SMART: DEAD-like helicase ; helicase YP_002987237.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002987238.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_002987239.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002987240.1 PFAM: ROK family protein; KEGG: eca:ECA1826 hypothetical protein YP_002987241.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002987242.1 KEGG: eca:ECA1828 hypothetical protein YP_002987244.1 with BtuD and BtuF transports vitamin B12 into the cell YP_002987245.1 PFAM: glutathione peroxidase; KEGG: eca:ECA1833 glutathione peroxidase YP_002987246.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1834 vitamin B12-transporter ATPase YP_002987247.1 PFAM: NLP/P60 protein; KEGG: spe:Spro_2161 NLP/P60 protein YP_002987248.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_002987249.1 PFAM: EAL domain protein; KEGG: eca:ECA1841 hypothetical protein YP_002987250.1 PFAM: protein of unknown function UPF0061; KEGG: spe:Spro_2164 hypothetical protein YP_002987251.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; peptidoglycan-binding protein; KEGG: eca:ECA2546 hypothetical protein YP_002987252.1 PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: eca:ECA2545 hypothetical protein YP_002987253.1 PFAM: beta-lactamase; KEGG: eca:ECA2544 metallo-beta-lactamase YP_002987254.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002987255.1 PFAM: porin Gram-negative type; KEGG: eca:ECA2542 outer membrane protein YP_002987256.1 PFAM: porin Gram-negative type; KEGG: eca:ECA2542 outer membrane protein YP_002987257.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002987258.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002987259.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: eca:ECA2539 aminopeptidase N YP_002987260.1 part of the ABC type transporter SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_002987261.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: esa:ESA_02406 alkanesulfonate transporter permease subunit YP_002987262.1 catalyzes the release of sulfite from alkanesulfonates YP_002987263.1 TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; SMART: extracellular solute-binding protein family 3; KEGG: spe:Spro_1738 alkanesulfonate transporter substrate-binding subunit YP_002987264.1 PFAM: NADPH-dependent FMN reductase; NAD(P)H dehydrogenase (quinone); KEGG: kpe:KPK_3595 NADPH-dependent FMN reductase YP_002987265.1 KEGG: eca:ECA2538 dihydroorotate dehydrogenase 2; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase YP_002987266.1 PFAM: protein of unknown function DUF1379; KEGG: eca:ECA2537 hypothetical protein YP_002987267.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; ferredoxin; KEGG: eca:ECA2536 iron-sulfur binding protein YP_002987268.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002987269.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002987270.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: eca:ECA2533 paraquat-inducible protein A YP_002987271.1 PFAM: hypothetical protein; KEGG: eca:ECA2532 paraquat-inducible protein B YP_002987272.1 PFAM: protein of unknown function DUF330; KEGG: eca:ECA2531 lipoprotein YP_002987273.1 PFAM: ribosome modulation factor; KEGG: yps:YPTB1448 ribosome modulation factor YP_002987274.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_002987275.1 PFAM: protein of unknown function DUF299; KEGG: eca:ECA1852 hypothetical protein YP_002987276.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002987277.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_002987278.1 PFAM: FAD linked oxidase; KEGG: eca:ECA1856 FAD-binding oxidase YP_002987279.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA1857 hypothetical protein YP_002987280.1 KEGG: eca:ECA1858 hypothetical protein YP_002987281.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA1865 hypothetical protein YP_002987282.1 PFAM: LPP repeat-containing protein; KEGG: eca:ECA1866 major outer membrane lipoprotein YP_002987283.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002987285.1 PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: eca:ECA1869 beta-glucoside operon antiterminator YP_002987286.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002987287.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA1871 6-phospho-beta-glucosidase YP_002987288.1 PFAM: porin LamB type; KEGG: ecl:EcolC_4274 porin LamB type YP_002987289.1 PFAM: esterase; glycoside hydrolase family 13 domain protein; KEGG: eca:ECA1873 glycosyl hydrolase exoenzyme YP_002987290.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE3194 acetyltransferase (GNAT) family protein YP_002987291.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: spe:Spro_0339 pyridoxal-5'-phosphate-dependent protein beta subunit YP_002987292.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: spe:Spro_0340 ornithine cyclodeaminase/mu-crystallin YP_002987293.1 PFAM: peptidase S45 penicillin amidase; KEGG: rme:Rmet_1578 peptidase S45, penicillin amidase YP_002987294.1 KEGG: bcm:Bcenmc03_1307 cyclic peptide transporter; TIGRFAM: cyclic peptide transporter; PFAM: ABC transporter related; SMART: ATPase AAA YP_002987295.1 TIGRFAM: amino acid adenylation protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: psb:Psyr_3722 amino acid adenylation YP_002987296.1 TIGRFAM: amino acid adenylation protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: eca:ECA1487 non-ribosomal peptide synthetase YP_002987297.1 TIGRFAM: amino acid adenylation protein; PFAM: AMP-dependent synthetase and ligase; thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase YP_002987298.1 PFAM: thioesterase; KEGG: bpd:BURPS668_A2592 thioesterase YP_002987299.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002987300.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002987301.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_002987302.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_002987303.1 PFAM: NLP/P60 protein; KEGG: ypa:YPA_1730 hypothetical protein YP_002987305.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: stm:STM1433 hypothetical protein YP_002987306.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002987307.1 KEGG: spe:Spro_2200 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase YP_002987308.1 transcription regulator that can both activate or repress expression YP_002987309.1 PFAM: 17 kDa surface antigen; KEGG: eca:ECA1932 outer membrane lipoprotein YP_002987310.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002987311.1 KEGG: eca:ECA1934 lipoprotein YP_002987312.1 KEGG: eca:ECA1935 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding YP_002987313.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002987314.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002987315.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA1938 glutathione S-transferase YP_002987316.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: eca:ECA1941 aconitate hydratase YP_002987317.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1942 periplasmic oligopeptide-binding protein YP_002987318.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_002987319.1 KEGG: eca:ECA1944 phosphatidylglycerophosphatase B; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related YP_002987320.1 PFAM: protein of unknown function DUF1049; KEGG: eca:ECA1955 hypothetical protein YP_002987321.1 SMART: hypothetical protein; KEGG: eca:ECA1956 hypothetical protein YP_002987322.1 KEGG: eta:ETA_16210 orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase YP_002987323.1 TIGRFAM: translation initiation factor SUI1; PFAM: translation initiation factor SUI1; KEGG: kpe:KPK_3156 translation initation factor SUI1 YP_002987324.1 KEGG: kpe:KPK_3155 osmotically-inducible lipoprotein B YP_002987325.1 TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; KEGG: eca:ECA1960 L-ribulose-5-phosphate 4-epimerase YP_002987326.1 transports degraded pectin products into the bacterial cell YP_002987327.1 PFAM: carbon starvation protein CstA; KEGG: spe:Spro_2639 carbon starvation protein CstA YP_002987328.1 PFAM: aldo/keto reductase; KEGG: eca:ECA1962 oxidoreductase YP_002987329.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002987330.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA1964 molybdopterin oxidoreductase YP_002987331.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1965 LysR family transcriptional regulator YP_002987332.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002987333.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1973 peptide transporter ATP-binding protein YP_002987334.1 KEGG: eca:ECA1974 peptide transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002987335.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1975 peptide transporter permease protein YP_002987336.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1976 peptide transporter permease protein YP_002987337.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1977 peptide transport periplasmic protein YP_002987338.1 PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA2530 methyl-accepting chemotaxis protein YP_002987339.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: spe:Spro_2626 cobalamin synthesis protein P47K YP_002987340.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_002987341.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_002987342.1 TIGRFAM: phage shock protein B; PFAM: shock B family protein; KEGG: spe:Spro_2623 phage shock protein B YP_002987343.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_002987344.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: eca:ECA1986 hypothetical protein YP_002987345.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1987 hypothetical protein YP_002987347.1 PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: eca:ECA1988 peptidase YP_002987348.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_002987349.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bbr:BB1022 acetyltransferase YP_002987350.1 KEGG: pap:PSPA7_4128 hypothetical protein YP_002987351.1 PFAM: major facilitator superfamily MFS_1; KEGG: pae:PA1262 major facilitator transporter YP_002987352.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002987353.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: eca:ECA1991 murein peptide amidase A YP_002987354.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1992 periplasmic murein peptide-binding protein YP_002987355.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: eca:ECA1993 zinc transporter YP_002987356.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002987357.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: bid:Bind_2498 flavin reductase domain-containing protein YP_002987360.1 PFAM: protein of unknown function DUF333; KEGG: eca:ECA1999 lipoprotein YP_002987361.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: eca:ECA2000 D-lactate dehydrogenase YP_002987362.1 KEGG: eca:ECA2002 aerotaxis receptor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer YP_002987363.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002987364.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_002987365.1 PFAM: protein of unknown function DUF162; KEGG: eca:ECA1918 hypothetical protein YP_002987366.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: cko:CKO_04246 hypothetical protein YP_002987367.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: elf:LF82_3514 uncharacterized protein YkgE YP_002987368.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: eca:ECA1921 L-lactate permease YP_002987369.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: eca:ECA2009 exported protease YP_002987370.1 PFAM: acid shock repeat protein; KEGG: sml:Smlt0383 histone H1-like protein YP_002987371.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA2012 sensor protein RstB YP_002987372.1 response regulator in two-component regulatory system with RstB YP_002987373.1 KEGG: spe:Spro_2588 hypothetical protein YP_002987374.1 TIGRFAM: sulfate transporter; PFAM: sulfate transporter; sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; KEGG: eca:ECA2021 sulfate transporter YchM YP_002987375.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: eca:ECA2022 calcium/sodium:proton antiporter YP_002987376.1 PFAM: cation transport protein ChaC; KEGG: eca:ECA2025 cation transporter YP_002987377.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_2915 binding-protein-dependent transport systems inner membrane component YP_002987378.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_2914 binding-protein-dependent transport systems inner membrane component YP_002987379.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: spe:Spro_2913 ABC transporter-related protein YP_002987380.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: spe:Spro_2912 ABC transporter-related protein YP_002987381.1 PFAM: extracellular solute-binding protein family 5; KEGG: eta:ETA_25780 ABC transporter periplasmic oligopeptide-binding protein YP_002987382.1 KEGG: eca:ECA2026 hypothetical protein YP_002987383.1 PFAM: acyltransferase 3; KEGG: eca:ECA2027 acyltransferase YP_002987384.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_002987385.1 KEGG: eca:ECA2029 nitrate/nitrite sensor protein NarX; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein YP_002987386.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2030 nitrite extrusion protein YP_002987387.1 PFAM: regulatory protein TetR; KEGG: dal:Dalk_0727 TetR family transcriptional regulator YP_002987388.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vfm:VFMJ11_A0422 NADH oxidase YP_002987389.1 KEGG: eca:ECA2031 respiratory nitrate reductase 1 alpha chain; TIGRFAM: nitrate reductase, subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_002987390.1 TIGRFAM: nitrate reductase subunit beta; KEGG: eca:ECA2032 respiratory nitrate reductase 1 beta chain YP_002987391.1 KEGG: eca:ECA2033 respiratory nitrate reductase 1 delta chain; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase subunit delta YP_002987392.1 KEGG: eca:ECA2034 respiratory nitrate reductase 1 gamma chain; TIGRFAM: respiratory nitrate reductase, subunit gamma; PFAM: nitrate reductase subunit gamma YP_002987393.1 PFAM: NUDIX hydrolase; KEGG: sit:TM1040_0128 NUDIX hydrolase YP_002987394.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ppr:PBPRA2519 alcohol dehydrogenase YP_002987396.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_002987397.1 PFAM: Domain of unknown function DUF1852; KEGG: spe:Spro_3175 hypothetical protein YP_002987398.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: esa:ESA_01873 4-oxalocrotonate tautomerase YP_002987399.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA3201 hypothetical protein YP_002987400.1 KEGG: eca:ECA2051 putitive ABC-transporter ATP-binding protein; TIGRFAM: spermidine/putrescine ABC transporter ATPase; PFAM: ABC transporter; transport-associated OB domain protein; SMART: AAA ATPase YP_002987401.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: eca:ECA2052 GntR family transcriptional regulator YP_002987402.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002987403.1 KEGG: eca:ECA2054 succinate-semialdehyde dehydrogenase [NADP+]; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_002987404.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2055 transporter, periplasmic solute-binding protein YP_002987405.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2056 transporter, permease protein YP_002987406.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2057 transporter, permease protein YP_002987407.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: esa:ESA_02175 hypothetical protein YP_002987408.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: ent:Ent638_0488 DeoR family transcriptional regulator YP_002987409.1 TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: eca:ECA2167 inositol monophosphatase YP_002987410.1 PFAM: major facilitator superfamily MFS_1; KEGG: psb:Psyr_3360 major facilitator transporter YP_002987411.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA1906 hydrolase YP_002987412.1 PFAM: NAD/NADP octopine/nopaline dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; Ketopantoate reductase ApbA/PanE domain protein; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: smd:Smed_3845 opine dehydrogenase YP_002987413.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rpi:Rpic_2081 LysR family transcriptional regulator YP_002987414.1 PFAM: FAD dependent oxidoreductase; KEGG: azc:AZC_3772 oxidoreductase YP_002987415.1 PFAM: alpha/beta hydrolase fold; KEGG: azc:AZC_3773 prolyl aminopeptidase YP_002987416.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: azc:AZC_3774 oligopeptide ABC transporter permease protein YP_002987417.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: azc:AZC_3775 oligopeptide ABC transporter permease protein YP_002987418.1 PFAM: peptidase M24; creatinase; KEGG: azc:AZC_3776 Xaa-Pro aminopeptidase YP_002987419.1 KEGG: azc:AZC_3777 oligopeptide ABC transporter; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_002987420.1 KEGG: azc:AZC_3778 peptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002987421.1 PFAM: extracellular solute-binding protein family 5; KEGG: azc:AZC_3779 extracellular solute-binding protein YP_002987423.1 KEGG: bxe:Bxe_B2355 hypothetical protein YP_002987424.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: yen:YE4139 methyl-accepting chemotaxis protein II YP_002987425.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1008 ABC transporter substrate-binding protein YP_002987426.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1007 ABC transporter permease YP_002987427.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1006 ABC transporter permease YP_002987428.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: eca:ECA1005 ABC transporter ATP-binding protein YP_002987429.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bbr:BB4185 oxidoreductase YP_002987430.1 KEGG: eca:ECA1004 hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_002987431.1 PFAM: FAD dependent oxidoreductase; KEGG: bja:blr2222 D-amino acid dehydrogenase small subunit YP_002987432.1 PFAM: regulatory protein TetR; KEGG: eca:ECA1003 TetR family transcription factor YP_002987433.1 PFAM: dihydrodipicolinate synthetase; KEGG: eca:ECA1002 dihydrodipicolinate synthase YP_002987434.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: yen:YE4139 methyl-accepting chemotaxis protein II YP_002987435.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_002987436.1 KEGG: hypothetical protein YP_002987437.1 PFAM: glutathione S-transferase domain; KEGG: kpn:KPN_03867 glutathione S-transferase YP_002987438.1 PFAM: GCN5-related N-acetyltransferase; KEGG: xau:Xaut_0311 GCN5-related N-acetyltransferase YP_002987439.1 PFAM: glycoside hydrolase family 1; KEGG: spe:Spro_0575 cryptic 6-phospho-beta-glucosidase YP_002987440.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002987441.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: ent:Ent638_3187 LacI family transcription regulator YP_002987442.1 KEGG: rpc:RPC_2976 hypothetical protein YP_002987443.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: vei:Veis_4467 ABC transporter YP_002987444.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bch:Bcen2424_6646 ABC transporter YP_002987445.1 PFAM: inner-membrane translocator; KEGG: bcm:Bcenmc03_6243 inner-membrane translocator YP_002987446.1 PFAM: inner-membrane translocator; KEGG: vei:Veis_4470 inner-membrane translocator YP_002987447.1 PFAM: extracellular ligand-binding receptor; KEGG: bch:Bcen2424_6643 extracellular ligand-binding receptor YP_002987448.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: ara:Arad_7293 transcriptional regulator protein YP_002987449.1 KEGG: Rnf183, RGD1564412_predicted; ring finger protein 183 YP_002987450.1 KEGG: kpe:KPK_1534 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent YP_002987451.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: azc:AZC_0730 transcriptional regulator YP_002987452.1 PFAM: extracellular solute-binding protein family 5; KEGG: rru:Rru_A0979 extracellular solute-binding protein YP_002987453.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: reh:H16_A2083 ABC-type transporter permease component: PepT family YP_002987454.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: rru:Rru_A0981 binding-protein dependent transport system inner membrane protein YP_002987455.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: reh:H16_A2085 ABC-type transporter duplicated ATPase domains:CUT2 family YP_002987456.1 PFAM: amidase; KEGG: aav:Aave_0191 amidase YP_002987457.1 KEGG: yen:YE2498 hypothetical protein YP_002987458.1 KEGG: spe:Spro_2453 hypothetical protein YP_002987459.1 PFAM: PepSY-associated TM helix domain protein; KEGG: eta:ETA_06010 iron-regulated membrane protein YP_002987460.1 KEGG: kpn:KPN_01710 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase YP_002987461.1 PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: kpn:KPN_01709 helix-turn-helix, AraC type YP_002987462.1 PFAM: major facilitator superfamily MFS_1; KEGG: pap:PSPA7_4707 MFS family transporter YP_002987463.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_002987464.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002987465.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002987466.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_002987467.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002987468.1 KEGG: spe:Spro_1987 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein YP_002987469.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002987470.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002987471.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002987472.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: efe:EFER_1749 N5-glutamine methyltransferase, modifies release factors RF-1 and RF-2 YP_002987473.1 KEGG: eca:ECA2193 transcriptional regulator YP_002987474.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002987475.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA2203 hypothetical protein YP_002987476.1 forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_002987477.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 subunit betas; AB-stereospecific enzyme YP_002987478.1 with UspC and UspD is involved in resistance to UV irradiation YP_002987479.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002987480.1 KEGG: eca:ECA2208 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylguanine DNA methyltransferase ribonuclease domain protein YP_002987481.1 PFAM: hypothetical protein; chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: esa:ESA_00603 hypothetical protein YP_002987482.1 PFAM: amine oxidase; KEGG: kpe:KPK_4913 amine oxidase flavin-containing YP_002987483.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: kpe:KPK_4910 MerR family transcriptional regulator YP_002987484.1 KEGG: eca:ECA2172 hypothetical protein YP_002987485.1 PFAM: ROK family protein; KEGG: atc:AGR_L_609 hypothetical protein YP_002987486.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: asu:Asuc_1528 ABC transporter YP_002987487.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ypy:YPK_2169 binding-protein-dependent transport systems inner membrane component YP_002987488.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: asu:Asuc_1526 binding-protein-dependent transport systems inner membrane component YP_002987489.1 PFAM: extracellular solute-binding protein family 1; KEGG: asu:Asuc_1525 extracellular solute-binding protein YP_002987490.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: psp:PSPPH_4534 glycerophosphodiester phosphodiesterase YP_002987491.1 PFAM: inositol monophosphatase; KEGG: pst:PSPTO_0659 inositol monophosphatase family protein YP_002987492.1 KEGG: rec:RHECIAT_PC0000667 hypothetical protein YP_002987493.1 KEGG: smd:Smed_5988 hypothetical protein YP_002987494.1 KEGG: eca:ECA2217 virulence factor YP_002987495.1 PFAM: virulence protein SrfB; KEGG: eca:ECA2218 virulence effector protein YP_002987496.1 KEGG: eca:ECA2219 virulence effector protein YP_002987497.1 PFAM: NmrA family protein; KEGG: yen:YE1738 hypothetical protein YP_002987498.1 KEGG: rso:RSc3165 hypothetical protein YP_002987499.1 PFAM: K potassium transporter; KEGG: spe:Spro_2547 K potassium transporter YP_002987500.1 KEGG: pat:Patl_1404 cellulase; PFAM: glycoside hydrolase family 5; carbohydrate-binding family V/XII; SMART: carbohydrate-binding family V/XII YP_002987501.1 KEGG: sde:Sde_2946 hypothetical protein YP_002987502.1 KEGG: spe:Spro_2341 mannosyl-3-phosphoglycerate phosphatase; TIGRFAM: mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; haloacid dehalogenase type 3 YP_002987503.1 KEGG: eca:ECA2249 hypothetical protein YP_002987504.1 PFAM: methyltransferase type 11; methyltransferase small; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: kpn:KPN_00225 biotin synthesis protein YP_002987505.1 PFAM: cytochrome P450; KEGG: xac:XAC3170 cytochrome P-450 hydroxylase YP_002987506.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_002987507.1 KEGG: eca:ECA2253 hypothetical protein YP_002987508.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002987509.1 PFAM: ROK family protein; KEGG: eca:ECA2258 transcriptional regulator YP_002987510.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2259 LysR family transcriptional regulator YP_002987511.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_2281 major facilitator transporter YP_002987512.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_002987513.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002987514.1 KEGG: kpe:KPK_2944 mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I YP_002987515.1 PFAM: protein of unknown function DUF945; KEGG: eca:ECA2264 hypothetical protein YP_002987516.1 KEGG: eca:ECA2266 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase YP_002987517.1 PFAM: Calcium/calmodulin dependent protein kinase II association-domain protein; KEGG: eca:ECA2267 hypothetical protein YP_002987518.1 PFAM: sodium symporter; KEGG: eca:ECA2268 sodium bile acid symporter YP_002987519.1 KEGG: cko:CKO_01579 hypothetical protein YP_002987520.1 PFAM: oxidoreductase domain protein; semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: eca:ECA2269 oxidoreductase YP_002987521.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_002987522.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002987523.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002987524.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA2273 L-arabinose-binding periplasmic protein YP_002987525.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_002987526.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_002987527.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_002987528.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: ypi:YpsIP31758_1894 Na(+)-translocating NADH-quinone reductase subunit E YP_002987529.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002987530.1 TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2278 electron transport complex protein RnfC YP_002987531.1 TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; KEGG: spe:Spro_2237 electron transport complex protein RnfD YP_002987532.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002987533.1 TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: yen:YE1988 SoxR-reducing system protein RsxE YP_002987534.1 KEGG: kpe:KPK_2378 endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop YP_002987535.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: spe:Spro_2656 transcriptional regulator CysB YP_002987536.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002987537.1 KEGG: eca:ECA2287 hypothetical protein YP_002987538.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002987539.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_1926 short chain dehydrogenase YP_002987540.1 KEGG: eca:ECA2290 cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_002987541.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_002987542.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: spe:Spro_2665 hypothetical protein YP_002987543.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: eca:ECA2293 phosphoesterase YP_002987544.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002987545.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002987546.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002987547.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002987548.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002987549.1 TIGRFAM: tryptophan synthase, subunit alpha; PFAM: tryptophan synthase alpha chain; KEGG: spe:Spro_2672 tryptophan synthase, subunit alpha YP_002987550.1 PFAM: oligogalacturonate-specific porin; KEGG: eca:ECA2407 oligogalacturonate-specific porin YP_002987551.1 receptor for colicin S4 YP_002987552.1 PFAM: protein of unknown function UPF0153; KEGG: esa:ESA_01555 hypothetical protein YP_002987553.1 PFAM: protein of unknown function UPF0259; KEGG: eca:ECA2305 hypothetical protein YP_002987554.1 TIGRFAM: intracellular septation protein A; PFAM: Intracellular septation protein A; KEGG: eca:ECA2313 intracellular septation protein A YP_002987555.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_002987556.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_002987557.1 PFAM: YCII-related; KEGG: cko:CKO_01328 YciI-like protein YP_002987558.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA2317 methyl-accepting chemotaxis protein YP_002987559.1 KEGG: ypi:YpsIP31758_1952 hypothetical protein YP_002987560.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002987561.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_002987562.1 KEGG: spe:Spro_2697 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002987563.1 KEGG: ect:ECIAI39_1581 oligopeptide transporter subunit ; ATP-binding component of ABC superfamily; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002987564.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: yen:YE2231 oligopeptide transporter permease protein YP_002987565.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2323 oligopeptide transporter permease YP_002987566.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2324 periplasmic oligopeptide-binding protein YP_002987567.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: eca:ECA2326 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002987568.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002987569.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA2328 global DNA-binding transcriptional dual regulator H-NS YP_002987570.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002987571.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA2330 response regulator of RpoS YP_002987572.1 PFAM: patatin; KEGG: eca:ECA2331 hypothetical protein YP_002987573.1 PFAM: SEC-C motif domain protein; KEGG: eca:ECA2332 hypothetical protein YP_002987574.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002987575.1 PFAM: protein of unknown function UPF0126; KEGG: eca:ECA2334 hypothetical protein YP_002987576.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: endonuclease/exonuclease/phosphatase; KEGG: ypi:YpsIP31758_1976 exonuclease III YP_002987577.1 PFAM: protein of unknown function DUF1496; KEGG: eca:ECA2336 hypothetical protein YP_002987578.1 decatenates replicating daughter chromosomes YP_002987579.1 PFAM: nitroreductase; KEGG: eca:ECA2338 hypothetical protein YP_002987580.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: eca:ECA2339 protease 4 YP_002987581.1 converts asparagine to aspartate and ammonia YP_002987582.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_002987583.1 PFAM: protein of unknown function DUF1315; KEGG: ypi:YpsIP31758_1985 hypothetical protein YP_002987584.1 KEGG: ypi:YpsIP31758_1986 methionine sulfoxide reductase B; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: methionine sulfoxide reductase B YP_002987585.1 KEGG: ypy:YPK_2096 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_002987586.1 PFAM: aldose 1-epimerase; KEGG: eca:ECA2345 aldose 1-epimerase YP_002987587.1 PFAM: aldo/keto reductase; KEGG: eca:ECA2346 aldo/keto reductase YP_002987588.1 PFAM: MltA-interacting MipA family protein; KEGG: eca:ECA2347 MltA-interacting protein YP_002987589.1 PFAM: PrkA AAA domain protein; PrkA serine kinase; SMART: PrkA AAA domain protein; KEGG: eca:ECA2348 hypothetical protein YP_002987590.1 PFAM: protein of unknown function DUF444; KEGG: spq:SPAB_02064 hypothetical protein YP_002987591.1 PFAM: metallophosphoesterase; KEGG: ecd:ECDH10B_1335 serine/threonine-protein phosphatase YP_002987592.1 KEGG: har:HEAR1364 hypothetical protein YP_002987593.1 catalyzes the oxidative deamination of D-amino acids YP_002987594.1 PFAM: SpoVR family protein; KEGG: eca:ECA2359 hypothetical protein YP_002987595.1 Multifunctional regulator of fatty acid metabolism YP_002987596.1 involved in regulation of intracellular pH under alkaline conditions YP_002987597.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002987599.1 PFAM: plasmid stabilization system; KEGG: spe:Spro_4208 plasmid stabilization system protein YP_002987600.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: ecm:EcSMS35_3216 addiction module antidote protein, CC2985 family YP_002987602.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_002987603.1 KEGG: plu:plu1132 hypothetical protein YP_002987604.1 KEGG: plu:plu1352 hypothetical protein YP_002987605.1 KEGG: plu:plu3694 hypothetical protein YP_002987606.1 PFAM: plasmid stabilization system; KEGG: eca:ECA1466 hypothetical protein YP_002987607.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: eca:ECA1467 hypothetical protein YP_002987608.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002987609.1 PFAM: zinc finger CHC2-family protein; DNA primase catalytic core domain; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; KEGG: plu:plu3714 hypothetical protein YP_002987610.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu1146 hypothetical protein YP_002987611.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_002987612.1 KEGG: plu:plu3717 hypothetical protein YP_002987613.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentous haemagglutinin domain protein; Haemagluttinin repeat-containing protein; protein of unknown function DUF638 hemagglutinin/hemolysin KEGG: ent:Ent638_0053 filamentous haemagglutinin outer membrane protein YP_002987614.1 PFAM: polypeptide-transport-associated domain protein ShlB-type; Hemolysin activator HlyB domain protein; KEGG: eca:ECA2116 hemolysin activator protein YP_002987615.1 PFAM: protein of unknown function UPF0153; KEGG: eca:ECA2365 hypothetical protein YP_002987616.1 PFAM: fumarylacetoacetate hydrolase; KEGG: eca:ECA2366 hypothetical protein YP_002987617.1 PFAM: protein of unknown function DUF709; KEGG: set:SEN1224 hypothetical protein YP_002987618.1 blocks the formation of polar Z-ring septums YP_002987619.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_002987620.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002987621.1 KEGG: eca:ECA2371 ribonuclease D; TIGRFAM: ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein YP_002987622.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA2372 long-chain-fatty-acid--CoA ligase YP_002987623.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: eca:ECA2373 outer membrane lipoprotein YP_002987624.1 PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein YP_002987625.1 SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 ATP-dependent helicase YP_002987627.1 PFAM: endoribonuclease L-PSP; KEGG: eca:ECA2376 endoribonuclease YP_002987628.1 PFAM: protein of unknown function UPF0181; KEGG: eum:ECUMN_2103 hypothetical protein YP_002987629.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: chorismate binding-like; anthranilate synthase component I domain protein; KEGG: yen:YE1781 para-aminobenzoate synthase component I YP_002987630.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA2379 hypothetical protein YP_002987631.1 KEGG: eca:ECA2380 L-serine dehydratase; TIGRFAM: L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_002987632.1 PFAM: integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA2384 hypothetical protein YP_002987633.1 KEGG: eca:ECA2385 PTS system, mannose-specific IIAB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIsubunit beta; PTS system, mannose/fructose/sorbose family, IIsubunit alpha; PFAM: PTS system sorbose subfamily IIB component; PTS system fructose subfamily IIA component YP_002987634.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: eca:ECA2386 PTS system, mannose-specific IIC component YP_002987635.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_002987636.1 PFAM: protein of unknown function DUF986; KEGG: eca:ECA2388 hypothetical protein YP_002987637.1 PFAM: protein of unknown function DUF204; KEGG: eca:ECA2389 hypothetical protein YP_002987638.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: eca:ECA2390 23S rRNA methyltransferase A YP_002987639.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: eca:ECA2391 cold shock-like protein CspC YP_002987640.1 PFAM: fructosamine kinase; aminoglycoside phosphotransferase; KEGG: eca:ECA2396 fructosamine kinase YP_002987641.1 KEGG: eca:ECA2397 hypothetical protein YP_002987642.1 PFAM: cupin; KEGG: eca:ECA2399 pectin degradation protein YP_002987643.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_002987644.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_002987645.1 PFAM: periplasmic pectate lyase; KEGG: eca:ECA2402 pectate disaccharide-lyase YP_002987646.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2403 binding-protein-dependent transport system, inner membrane component YP_002987647.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ent:Ent638_3290 binding-protein-dependent transport systems inner membrane component YP_002987648.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: eca:ECA2405 ABC transporter ATP-binding component YP_002987649.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2406 periplasmic pectic oligomers binding protein YP_002987650.1 PFAM: oligogalacturonate-specific porin; KEGG: eca:ECA2407 oligogalacturonate-specific porin YP_002987651.1 KEGG: eca:ECA2408 pectin acetylesterase YP_002987652.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA2410 sodium:dicarboxylate symporter YP_002987653.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_002987655.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002987656.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA2413 hypothetical protein YP_002987657.1 KEGG: eca:ECA2415 hypothetical protein YP_002987658.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002987659.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002987660.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002987661.1 TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; KEGG: eum:ECUMN_2006 50S ribosomal subunit protein L20 YP_002987662.1 TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: eca:ECA2420 50S ribosomal protein L35 YP_002987663.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002987664.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002987665.1 KEGG: eca:ECA2424 hypothetical protein YP_002987666.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: eca:ECA2425 pectin degradation repressor YP_002987667.1 KEGG: eca:ECA2426 oligogalacturonate lyase YP_002987668.1 PFAM: HtpX domain protein; peptidase M48 Ste24p; KEGG: kpn:KPN_02345 heat shock protein HtpX YP_002987669.1 KEGG: eca:ECA2433 signaling protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein YP_002987670.1 Converts isocitrate to alpha ketoglutarate YP_002987671.1 PFAM: pseudouridine synthase; KEGG: eca:ECA2440 RNA pseudouridylate synthase YP_002987672.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA2441 MutT family protein YP_002987673.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002987674.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002987675.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002987676.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_002987677.1 PFAM: PhoQ Sensor domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: eca:ECA2446 sensor protein PhoQ YP_002987678.1 PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: eca:ECA2447 hypothetical protein YP_002987679.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002987680.1 PFAM: protein of unknown function DUF1920; KEGG: rru:Rru_A2471 hypothetical protein YP_002987681.1 TIGRFAM: ferrous iron transporter B; small GTP-binding protein; PFAM: Ferrous iron transporter B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; KEGG: rru:Rru_A2470 ferrous iron transporter B YP_002987682.1 PFAM: FeoA family protein; KEGG: rru:Rru_A2469 hypothetical protein YP_002987683.1 PFAM: FeoA family protein; KEGG: rsk:RSKD131_0125 FeoA family protein YP_002987684.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002987685.1 PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: eca:ECA2461 hypothetical protein YP_002987686.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: eca:ECA2462 hypothetical protein YP_002987687.1 PFAM: hypothetical protein; KEGG: eca:ECA2463 hypothetical protein YP_002987688.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002987689.1 PFAM: protein of unknown function DUF1482; KEGG: set:SEN1185 secreted protein YP_002987690.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: yen:YE4139 methyl-accepting chemotaxis protein II YP_002987691.1 PFAM: CI repressor; SMART: helix-turn-helix domain protein; KEGG: spe:Spro_0877 CI repressor YP_002987692.1 KEGG: ecz:ECS88_2224 replication gene B protein (GpB) YP_002987693.1 KEGG: eca:ECA2631 hypothetical protein YP_002987694.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: spe:Spro_0875 TraR/DksA family transcriptional regulator YP_002987695.1 PFAM: replication gene A; KEGG: ecw:EcE24377A_0988 replication gene A protein YP_002987697.1 PFAM: tail X family protein; KEGG: ecf:ECH74115_3047 phage tail protein GpX YP_002987698.1 PFAM: P2 phage tail completion R family protein; KEGG: ecz:ECS88_2203 tail completion protein R (GpR) YP_002987699.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: ecm:EcSMS35_4337 phage baseplate assembly protein GpV YP_002987700.1 PFAM: GPW/gp25 family protein; KEGG: kpn:KPN_04869 prophage baseplate protein YP_002987701.1 PFAM: Baseplate J family protein; KEGG: ecf:ECH74115_3037 baseplate assembly protein GpJ YP_002987702.1 TIGRFAM: phage tail protein I; KEGG: eca:ECA2609 phage tail protein I YP_002987703.1 KEGG: spe:Spro_1010 hypothetical protein YP_002987704.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: spe:Spro_2512 major facilitator transporter YP_002987705.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: ecg:E2348C_1532 hypothetical protein YP_002987706.1 PFAM: Tail Collar domain protein; KEGG: plu:plu0021 hypothetical protein YP_002987707.1 PFAM: tail assembly chaperone gp38; KEGG: eca:ECA2607 bacteriophage tail fiber assembly protein G YP_002987708.1 PFAM: tail sheath protein; KEGG: kpn:KPN_04864 prophage tail sheath YP_002987709.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: see:SNSL254_A4384 phage major tail tube protein YP_002987710.1 PFAM: tail E family protein; KEGG: ecq:ECED1_2437 tail protein E (GpE) YP_002987711.1 PFAM: P2 GpE family protein; KEGG: kpn:KPN_04861 prophage tail protein YP_002987712.1 KEGG: kpn:KPN_04860 prophage tail length determinator YP_002987713.1 PFAM: P2 GpU family protein; KEGG: see:SNSL254_A4388 GP25 YP_002987714.1 PFAM: late control D family protein; KEGG: see:SNSL254_A4389 late control gene D protein YP_002987715.1 PFAM: transcriptional activator Ogr/delta; KEGG: ecg:E2348C_2893 predicted DNA-binding transcriptional regulator YP_002987716.1 KEGG: spe:Spro_2420 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; hypothetical protein; SMART: GGDEF domain containing protein; GAF domain protein; PAS domain containing protein YP_002987717.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: efe:EFER_3055 methyl-accepting chemotaxis protein I, serine sensor receptor YP_002987718.1 PFAM: ThiJ/PfpI domain protein; KEGG: pfo:Pfl01_1835 ThiJ/PfpI YP_002987719.1 PFAM: holin family 2; KEGG: eca:ECA2617 phage lysis protein Y, holin YP_002987720.1 PFAM: glycoside hydrolase family 24; KEGG: ecm:EcSMS35_4330 phage lysozyme YP_002987721.1 KEGG: eca:ECA2615 phage encoded host lysis, regulatory protein YP_002987722.1 KEGG: eca:ECA2614A phage protein (thought to be involved in host lysis) YP_002987723.1 PFAM: OsmC family protein; KEGG: bcj:BCAM2803 stress-induced protein YP_002987724.1 PFAM: hypothetical protein; KEGG: eca:ECA2048 hypothetical protein YP_002987725.1 PFAM: protein of unknown function DUF1501; KEGG: avi:Avi_3565 hypothetical protein YP_002987726.1 PFAM: chitin synthase; KEGG: eca:ECA2046 bifunctional enzyme including aminotransferase and chitin synthase YP_002987728.1 KEGG: kpn:KPN_00487 hypothetical protein YP_002987729.1 PFAM: protein of unknown function DUF465; KEGG: cko:CKO_01463 hypothetical protein YP_002987730.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: set:SEN2387 acyltransferase YP_002987731.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: eca:ECA2471 cold shock protein YP_002987732.1 KEGG: eca:ECA2472 hypothetical protein YP_002987733.1 PFAM: ferritin; KEGG: eca:ECA2473 ferritin YP_002987734.1 PFAM: copper resistance D domain protein; KEGG: ses:SARI_01072 hypothetical protein YP_002987735.1 PFAM: DNA polymerase II subunit beta; KEGG: spe:Spro_1941 DNA polymerase III subunit theta YP_002987737.1 KEGG: ypi:YpsIP31758_2345 hypothetical protein YP_002987738.1 PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: eca:ECA2476 protease II YP_002987739.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_002987740.1 PFAM: protein of unknown function DUF606; KEGG: slo:Shew_2290 hypothetical protein YP_002987741.1 PFAM: protein of unknown function DUF606; KEGG: slo:Shew_2291 hypothetical protein YP_002987742.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: cvi:CV_3482 LysR family transcriptional regulator YP_002987743.1 PFAM: glycoside hydrolase family 30; KEGG: xcv:XCV0965 xylanase precursor YP_002987744.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002987745.1 KEGG: eca:ECA2479 glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase YP_002987746.1 Represses the expression of the zwf, eda, glp and gap YP_002987747.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002987748.1 KEGG: hch:HCH_05781 hypothetical protein YP_002987749.1 transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_002987750.1 PFAM: peptidase M23; peptidoglycan-binding LysM; Opacity-associated protein A; Opacity-associated protein A domain protein; SMART: peptidoglycan-binding LysM; KEGG: eca:ECA2483 hypothetical protein YP_002987751.1 involved in transport of zinc(II) with ZnuA and C YP_002987752.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2485 high-affinity zinc transporter ATPase YP_002987753.1 involved in transport of zinc(II) with ZnuA and C YP_002987754.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002987755.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002987756.1 TIGRFAM: high-affinity nickel-transporter; PFAM: high-affinity nickel-transporter; KEGG: esa:ESA_02056 hypothetical protein YP_002987757.1 TIGRFAM: transketolase; PFAM: transketolase central region; transketolase; KEGG: esa:ESA_00406 transketolase YP_002987758.1 KEGG: kpe:KPK_3427 transaldolase; TIGRFAM: transaldolase; PFAM: transaldolase YP_002987759.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_002987760.1 PFAM: PTS system glucitol/sorbitol-specific IIA component; KEGG: kpn:KPN_01124 PTS family enzyme IIA, glucitol/sorbitol-specific YP_002987761.1 transports degraded pectin products into the bacterial cell YP_002987762.1 PFAM: Sorbitol phosphotransferase protein II domain protein; type III effector Hrp-dependent outers; KEGG: kpn:KPN_01122 glucitol/sorbitol-specific PTS family protein IIBC YP_002987763.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002987764.1 TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; KEGG: kpe:KPK_3433 triosephosphate isomerase YP_002987765.1 PFAM: sugar-binding domain protein; KEGG: kpe:KPK_3434 sugar-binding domain protein YP_002987766.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002987767.1 PFAM: protein of unknown function DUF28; KEGG: eca:ECA2494 hypothetical protein YP_002987768.1 converts dATP to dAMP and pyrophosphate YP_002987769.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002987770.1 PFAM: protein of unknown function DUF72; KEGG: spe:Spro_2784 hypothetical protein YP_002987771.1 PFAM: protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: ypi:YpsIP31758_4090 hypothetical protein YP_002987772.1 KEGG: ypy:YPK_0073 hypothetical protein YP_002987773.1 PFAM: alanine racemase domain protein; KEGG: pub:SAR11_0361 hypothetical protein YP_002987774.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002987775.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypg:YpAngola_A4139 pyridoxal-phosphate dependent protein YP_002987776.1 KEGG: eca:ECA2510 hypothetical protein YP_002987777.1 TIGRFAM: methyltransferase; PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: spe:Spro_2786 methyltransferase YP_002987778.1 TIGRFAM: methyltransferase; PFAM: methyltransferase ; methyltransferase type 11; KEGG: eca:ECA2512 hypothetical protein YP_002987780.1 PFAM: CutC family protein; KEGG: eca:ECA2518 copper homeostasis protein CutC YP_002987781.1 PFAM: protein of unknown function DUF991; KEGG: eca:ECA2519 hypothetical protein YP_002987782.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002987783.1 PFAM: EAL domain protein; metal-dependent hydrolase HDOD; KEGG: esa:ESA_01854 hypothetical protein YP_002987784.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: rme:Rmet_0160 methyl-accepting chemotaxis sensory transducer YP_002987785.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: eca:ECA2521 virulence factor YP_002987786.1 PFAM: oxidoreductase domain protein; KEGG: yps:YPTB2025 oxidoreductase YP_002987787.1 PFAM: protein of unknown function DUF480; KEGG: eca:ECA2523 hypothetical protein YP_002987788.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2524 ribosomal-protein-S5-alanine N-acetyltransferase YP_002987790.1 Confers resistance to norfloxacin and enoxacin YP_002987791.1 TIGRFAM: glutaredoxin, GrxB family; PFAM: glutaredoxin 2 domain protein; KEGG: eca:ECA2526 glutaredoxin 2 YP_002987792.1 PFAM: protein of unknown function DUF1439; KEGG: eca:ECA2527 hypothetical protein YP_002987793.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein YP_002987794.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: eca:ECA2529 hydrolase YP_002987795.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bra:BRADO0021 haloacid dehalogenase-like hydrolase family protein; phosphoglycolate phosphatase YP_002987796.1 PFAM: endoribonuclease L-PSP; KEGG: pmr:PMI3427 endoribonuclease YP_002987798.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; SMART: regulatory protein MarR; KEGG: dac:Daci_5296 MarR family transcriptional regulator YP_002987799.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: esa:ESA_02953 hypothetical protein YP_002987800.1 PFAM: NUDIX hydrolase; KEGG: spe:Spro_2260 NUDIX hydrolase YP_002987801.1 PFAM: ribonuclease T2; KEGG: pfo:Pfl01_3807 ribonuclease T2 YP_002987802.1 PFAM: NUDIX hydrolase; KEGG: hypothetical protein YP_002987803.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bbt:BBta_2707 oxidoreductase YP_002987804.1 PFAM: helix-turn-helix HxlR type; KEGG: bbt:BBta_2706 transcriptional regulator YP_002987805.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_002987807.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002987808.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002987809.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002987810.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002987811.1 PFAM: protein of unknown function DUF218; KEGG: eca:ECA2551 hypothetical protein YP_002987812.1 PFAM: aminoglycoside phosphotransferase; KEGG: eca:ECA2552 hypothetical protein YP_002987813.1 KEGG: eca:ECA2553 pectate lyase YP_002987814.1 KEGG: eca:ECA2554 3-deoxy-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase YP_002987815.1 PFAM: protein of unknown function DUF343; KEGG: eca:ECA2555 hypothetical protein YP_002987816.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_002987817.1 involved in the transport of lipid A across the inner membrane YP_002987818.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase; KEGG: eca:ECA2558 hypothetical protein YP_002987819.1 PFAM: protein of unknown function DUF496; KEGG: eca:ECA2560 hypothetical protein YP_002987820.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002987821.1 PFAM: amino acid permease-associated region; KEGG: eta:ETA_13600 amino acid permease YP_002987823.1 PFAM: YcgR family protein; type IV pilus assembly PilZ; KEGG: eca:ECA2568 hypothetical protein YP_002987824.1 KEGG: eca:ECA2569 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; PFAM: triphosphoribosyl-dephospho-CoA protein YP_002987825.1 KEGG: eca:ECA2570 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; TIGRFAM: holo-ACP synthase CitX; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase YP_002987826.1 KEGG: eca:ECA2571 citrate lyase alpha chain; TIGRFAM: citrate lyase subunit alpha; PFAM: citrate lyase subunit alpha YP_002987827.1 KEGG: eca:ECA2572 citrate lyase beta chain; TIGRFAM: citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase YP_002987828.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_002987829.1 KEGG: eca:ECA2574 [citrate [pro-3s]-lyase] ligase; TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: citrate lyase ligase domain protein; GCN5-related N-acetyltransferase; cytidylyltransferase; SMART: citrate lyase ligase domain protein YP_002987830.1 PFAM: fumarylacetoacetate hydrolase; KEGG: eca:ECA2575 fumarylacetoacetate hydrolase YP_002987831.1 PFAM: citrate carrier protein; KEGG: eca:ECA2576 citrate/acetate antiporter YP_002987833.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; KEGG: eca:ECA2577 two-component sensor kinase YP_002987834.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA2578 two-component response regulator YP_002987835.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ypg:YpAngola_A3076 hypothetical protein YP_002987836.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002987837.1 KEGG: eca:ECA2583 histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: histidinol dehydrogenase YP_002987838.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002987839.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002987840.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002987841.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002987842.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002987843.1 TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-AMP cyclohydrolase; KEGG: eca:ECA2589 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_002987844.1 KEGG: plu:plu3101 hypothetical protein YP_002987845.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002987846.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002987847.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002987848.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002987849.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002987850.1 PFAM: protein of unknown function DUF181; KEGG: eca:ECA2595 hypothetical protein YP_002987851.1 TIGRFAM: formate/nitrite transporter; PFAM: formate/nitrite transporter; KEGG: eca:ECA2596 formate transporter YP_002987852.1 KEGG: eca:ECA2597 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_002987854.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_002987855.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: eca:ECA2642 LysR family transcriptional regulator YP_002987856.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2643 MFS family transporter YP_002987857.1 KEGG: rpi:Rpic_1321 hypothetical protein YP_002987858.1 PFAM: glutathione S-transferase domain; KEGG: swi:Swit_0510 glutathione S-transferase domain-containing protein YP_002987859.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: ypy:YPK_3391 cytoplasmic chaperone TorD family protein YP_002987860.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: yps:YPTB0807 anaerobic dimethyl sulfoxide reductase, subunit C YP_002987861.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: esa:ESA_01745 hypothetical protein YP_002987862.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: ent:Ent638_1418 anaerobic dimethyl sulfoxide reductase subunit A YP_002987863.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: spe:Spro_1687 anaerobic dimethyl sulfoxide reductase subunit A YP_002987864.1 KEGG: eca:ECA2644 seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like YP_002987865.1 PFAM: ATPase AAA; magnesium chelatase ChlI subunit; SMART: ATPase AAA; KEGG: eca:ECA2645 recombination factor protein RarA YP_002987866.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002987867.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: eca:ECA2647 cell division protein YP_002987868.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transporter YP_002987869.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA2649 thioredoxin reductase YP_002987870.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002987871.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002987872.1 KEGG: ypa:YPA_0661 leucyl/phenylalanyl-tRNA--protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA/protein transferase; PFAM: leucyl/phenylalanyl-tRNA--protein transferase YP_002987873.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002987874.1 KEGG: eca:ECA2656 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: ATPase AAA; ATPase AAA; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA YP_002987875.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: eca:ECA2657 ATP-dependent Clp protease adaptor protein ClpS YP_002987876.1 KEGG: stm:STM0943 stress response protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_002987877.1 KEGG: eca:ECA2660 hypothetical protein YP_002987878.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002987879.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: eca:ECA2663 HCP oxidoreductase, NADH-dependent YP_002987880.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: eca:ECA2664 hypothetical protein YP_002987881.1 KEGG: eca:ECA2665 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2 YP_002987882.1 PFAM: protein of unknown function DUF74; KEGG: spe:Spro_1658 hypothetical protein YP_002987883.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2667 arginine transporter ATP-binding subunit YP_002987884.1 KEGG: eca:ECA2668 arginine-binding periplasmic protein 1; TIGRFAM: cationic amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor YP_002987885.1 with ArtPMJI transports arginine across the inner membrane YP_002987886.1 with ArtPQJI acts to transport arginine across the inner membrane YP_002987887.1 KEGG: eca:ECA2671 arginine-binding periplasmic protein 2; TIGRFAM: cationic amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor YP_002987888.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpe:KPK_5075 transporter major facilitator family YP_002987889.1 KEGG: eca:ECA2673 hypothetical protein YP_002987890.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2674 putrescine ABC transporter membrane protein YP_002987891.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2675 putrescine ABC transporter membrane protein YP_002987892.1 part of the PotFGHI ATP-dependent putrescine transporter YP_002987893.1 PFAM: extracellular solute-binding protein family 1; KEGG: yen:YE1484 putrescine ABC transporter periplasmic substrate-binding protein YP_002987894.1 KEGG: eca:ECA2678 hypothetical protein YP_002987895.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: eca:ECA2679 ribosomal protein S6 modification protein YP_002987896.1 PFAM: nitroreductase; KEGG: stm:STM0874 nitroreductase A YP_002987897.1 TIGRFAM: glutaredoxin, GrxA family; PFAM: glutaredoxin; KEGG: eca:ECA2681 glutaredoxin 1 YP_002987898.1 KEGG: eca:ECA2682 hypothetical protein YP_002987899.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; KEGG: eca:ECA2683 hypothetical protein YP_002987900.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA2685 DNA-binding transcriptional repressor DeoR YP_002987901.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; beta-lactamase; Penicillin-binding protein 5 domain protein; KEGG: eca:ECA2686 penicillin-binding protein 6 YP_002987902.1 PFAM: alpha/beta hydrolase fold; KEGG: psp:PSPPH_3042 3-hydroxyacyl-CoA-acyl carrier protein transferase YP_002987903.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2687 ABC transporter integral membrane protein YP_002987904.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2688 ABC transporter ATP-binding protein YP_002987905.1 PFAM: NLPA lipoprotein; KEGG: eca:ECA2689 lipoprotein YP_002987906.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA2690 glutathione S-transferase YP_002987907.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: reh:H16_A3224 transcriptional regulator, LysR-family YP_002987908.1 PFAM: Tannase and feruloyl esterase; KEGG: ara:Arad_12198 feruloyl esterase YP_002987909.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_002987910.1 PFAM: protein of unknown function DUF218; KEGG: eca:ECA2709 hypothetical protein YP_002987911.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: eca:ECA2710 hypothetical protein YP_002987912.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002987913.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1509 methyl-accepting chemotaxis protein YP_002987914.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA2712 methyl-accepting chemotaxis protein YP_002987915.1 KEGG: eca:ECA2712 methyl-accepting chemotaxis protein YP_002987916.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2713 LysR family transcriptional regulator YP_002987917.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: spe:Spro_1557 S-(hydroxymethyl)glutathione dehydrogenase YP_002987918.1 KEGG: ypi:YpsIP31758_2474 S-formylglutathione hydrolase; TIGRFAM: S-formylglutathione hydrolase; PFAM: esterase YP_002987919.1 KEGG: eca:ECA2717 hypothetical protein YP_002987920.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_002987921.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2719 ABC transporter ATP-binding protein YP_002987922.1 PFAM: inner-membrane translocator; KEGG: eca:ECA2720 ABC transporter permease YP_002987923.1 KEGG: bha:BH1839 hypothetical protein YP_002987924.1 PFAM: catalytic domain of components of various dehydrogenase complexes; KEGG: bha:BH1847 hypothetical protein YP_002987926.1 TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; KEGG: bha:BH1845 hypothetical protein YP_002987927.1 KEGG: bha:BH1844 3-oxoacyl-[acyl-carrier-protein] synthase III YP_002987928.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_3194 sugar efflux transporter YP_002987929.1 PFAM: amino acid permease-associated region; KEGG: yps:YPTB1340 lysine transporter YP_002987930.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2724 DNA-binding transcriptional regulator YP_002987931.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA2725 hypothetical protein YP_002987932.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002987933.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002987934.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_002987935.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_002987936.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2730 sugar efflux transporter YP_002987937.1 PFAM: protein of unknown function UPF0153; KEGG: eca:ECA2731 hypothetical protein YP_002987938.1 TIGRFAM: elongation factor P-like protein YeiP; PFAM: Elongation factor P ; Elongation factor P/YeiP protein; Elongation factor KOW domain protein; KEGG: spe:Spro_3237 elongation factor P-like protein YeiP YP_002987939.1 PFAM: cobalamin synthesis protein P47K; KEGG: eca:ECA2733 hypothetical protein YP_002987940.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: eca:ECA2734 membrane-bound phosphatase YP_002987941.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_002987942.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2736 ABC transporter periplasmic protein YP_002987943.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2737 binding-protein-dependent transporter YP_002987944.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2738 ABC transporter permease YP_002987945.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2739 ABC-transporter ATP-binding protein YP_002987946.1 PFAM: transposase IS3/IS911 family protein; KEGG: ecx:EcHS_A4530 ISEhe3, transposase orfA YP_002987947.1 PFAM: Integrase catalytic region; KEGG: ecx:EcHS_A4529 ISEhe3, transposase orfB YP_002987948.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: xcb:XC_2435 hypothetical protein YP_002987949.1 KEGG: pla:Plav_0317 hypothetical protein YP_002987950.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: pap:PSPA7_0134 ThiF family protein YP_002987951.1 KEGG: pap:PSPA7_0135 hypothetical protein YP_002987952.1 KEGG: pap:PSPA7_0136 hypothetical protein YP_002987953.1 TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: rso:RSc2620 hypothetical protein YP_002987954.1 PFAM: protein of unknown function DUF1016; KEGG: zmo:ZMO1931 hypothetical protein YP_002987955.1 KEGG: eca:ECA2740 hypothetical protein YP_002987956.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002987957.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_002987958.1 KEGG: eca:ECA2743 hypothetical protein YP_002987959.1 PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicase ; helicase; KEGG: eca:ECA2744 helicase YP_002987960.1 PFAM: ribosomal protein L25; KEGG: kpe:KPK_1543 ribosomal L25p family YP_002987961.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2430 hypothetical protein YP_002987962.1 PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: kpn:KPN_02737 2-component transcriptional regulator YP_002987963.1 KEGG: eta:ETA_11160 sensor protein; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein YP_002987964.1 PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein NdpA YP_002987965.1 PFAM: protein of unknown function DUF1414; KEGG: yen:YE1420 hypothetical protein YP_002987966.1 PFAM: sulfatase; KEGG: eca:ECA2749 sulphatase YP_002987967.1 PFAM: integrase family protein; KEGG: eca:ECA2750 prophage integrase YP_002987968.1 KEGG: ypb:YPTS_3242 hypothetical protein YP_002987969.1 PFAM: prophage CP4-57 regulator; KEGG: eca:ECA2752 hypothetical protein YP_002987970.1 KEGG: ecr:ECIAI1_1591 conserved hypothetical protein; Qin prophage YP_002987971.1 KEGG: ecg:E2348C_3903 hypothetical protein YP_002987972.1 KEGG: eca:ECA1671 hypothetical protein YP_002987973.1 PFAM: protein of unknown function DUF927; P4 alpha zinc-binding domain protein; SMART: P4 alpha zinc-binding domain protein; KEGG: eta:ETA_24220 prophage primase YP_002987974.1 KEGG: ppd:Ppro_3130 hypothetical protein YP_002987975.1 SMART: ATPase AAA; KEGG: pmr:PMI2355 hypothetical protein YP_002987976.1 KEGG: pmr:PMI2356 reverse transcriptase YP_002987977.1 KEGG: sbc:SbBS512_E4092 hypothetical protein YP_002987978.1 KEGG: bam:Bamb_1706 hypothetical protein YP_002987979.1 KEGG: ent:Ent638_1881 hypothetical protein YP_002987981.1 KEGG: hin:HI1492 hypothetical protein YP_002987982.1 PFAM: GlpM family protein; KEGG: eca:ECA0108 hypothetical protein YP_002987983.1 PFAM: heat shock protein Hsp20; KEGG: ses:SARI_01731 hypothetical protein YP_002987984.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: bmj:BMULJ_02890 hypothetical protein YP_002987985.1 KEGG: pap:PSPA7_0599 biotin-dependent carboxylase domain-containing protein; TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; SMART: allophanate hydrolase subunit 2 YP_002987986.1 PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1; KEGG: pag:PLES_04911 hydrolase YP_002987987.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002987988.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: vei:Veis_4578 hypothetical protein YP_002987989.1 PFAM: LamB/YcsF family protein; KEGG: pae:PA0492 hypothetical protein YP_002987990.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ppf:Pput_2773 LysR family transcriptional regulator YP_002987991.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2763 transporter YP_002987992.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmn:BMA10247_0906 MarR family transcriptional regulator YP_002987993.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_002987994.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA2765 threonine and homoserine efflux system YP_002987995.1 similar to periplasmic-binding component of ABC transporters YP_002987996.1 similar to permease of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002987997.1 similar to ATP-binding component of ABC transporters YP_002987998.1 PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: afw:Anae109_2327 cell surface receptor IPT/TIG domain-containing protein YP_002987999.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: eca:ECA2062 phosphatase YP_002988000.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: eca:ECA2771 peptidase YP_002988001.1 PFAM: glycosyl transferase, family 3-like; KEGG: eca:ECA2772 hypothetical protein YP_002988002.1 helicase involved in DNA repair and perhaps also replication YP_002988003.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA2787 AraC family transcription regulator YP_002988004.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA2788 LysE family translocator YP_002988006.1 PFAM: glycoside hydrolase; KEGG: eca:ECA2790 periplasmic beta-glucosidase YP_002988007.1 PFAM: aminotransferase class-III; KEGG: eta:ETA_34300 aminotransferase YP_002988008.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: eta:ETA_34310 DeoR family transcriptional regulator YP_002988009.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA2791 glutathione S-transferase YP_002988010.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_002988011.1 TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: eca:ECA2795 adenylate cyclase YP_002988013.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pae:PA1129 fosfomycin resistance protein YP_002988014.1 PFAM: dihydrouridine synthase; KEGG: kpn:KPN_02581 tRNA-dihydrouridine synthase C YP_002988015.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2801 periplasmic dipeptide transporter YP_002988016.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002988017.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1743 AraC family transcriptional regulator YP_002988018.1 KEGG: net:Neut_2215 hypothetical protein YP_002988022.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: kpn:KPN_01938 transmembrane protein YP_002988023.1 PFAM: DEAD/DEAH box helicase; helicase domain protein; SMART: DEAD-like helicase ; helicase; KEGG: eca:ECA2805 ATP-dependent RNA helicase RhlE YP_002988024.1 PFAM: secretion protein HlyD; KEGG: ypy:YPK_2900 secretion protein HlyD YP_002988025.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ypy:YPK_2901 ABC transporter YP_002988026.1 PFAM: ABC transporter; KEGG: spe:Spro_1327 ABC-2 type transporter YP_002988027.1 PFAM: ABC transporter; KEGG: spe:Spro_1326 ABC-2 type transporter YP_002988028.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: kpn:KPN_00818 DNase YP_002988029.1 PFAM: phospholipase D/transphosphatidylase; SMART: phospholipase D/transphosphatidylase; KEGG: kpe:KPK_3754 cardiolipin synthetase YP_002988030.1 PFAM: Auxin Efflux Carrier; KEGG: pna:Pnap_2164 auxin efflux carrier YP_002988031.1 PFAM: protein of unknown function UPF0005; KEGG: spe:Spro_1325 hypothetical protein YP_002988032.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: spe:Spro_2536 ABC transporter-related protein YP_002988033.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_2535 binding-protein-dependent transport systems inner membrane component YP_002988034.1 PFAM: extracellular solute-binding protein family 1; KEGG: spe:Spro_2534 extracellular solute-binding protein YP_002988035.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002988036.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit YP_002988037.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: eca:ECA2815 molybdenum cofactor biosynthesis protein C YP_002988038.1 TIGRFAM: molybdenum cofactor biosynthesis protein B; molybdenum cofactor synthesis protein; PFAM: molybdopterin binding domain; KEGG: eca:ECA2816 molybdenum cofactor biosynthesis protein B YP_002988039.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002988040.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: eca:ECA2818 hypothetical protein YP_002988041.1 KEGG: eca:ECA2819 hypothetical protein YP_002988042.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-subunit beta is inserted between the strands, where it probes for the presence of a lesion YP_002988043.1 KEGG: spe:Spro_1314 dithiobiotin synthetase; TIGRFAM: dethiobiotin synthase; PFAM: cobyrinic acid ac-diamide synthase YP_002988044.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: eca:ECA2823 biotin synthesis protein YP_002988045.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002988046.1 KEGG: eca:ECA2825 biotin synthase; TIGRFAM: biotin synthase; PFAM: biotin and thiamin synthesis associated; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_002988047.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002988048.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2256 transporter YP_002988049.1 PFAM: AraC protein arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bur:Bcep18194_B2671 AraC family transcriptional regulator YP_002988050.1 PFAM: glycoside hydrolase; KEGG: bam:Bamb_4300 beta-glucosidase YP_002988051.1 PFAM: LrgA family protein; KEGG: eca:ECA2828 hypothetical protein YP_002988052.1 PFAM: LrgB family protein; KEGG: yen:YE2791 hypothetical protein YP_002988053.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002988055.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002988056.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: eca:ECA2836 molybdopterin biosynthesis protein MoeA YP_002988057.1 TIGRFAM: molybdopterin synthase sulfurylase MoeB; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spe:Spro_1546 molybdopterin biosynthesis protein MoeB YP_002988058.1 PFAM: thioesterase superfamily protein; KEGG: pmr:PMI1691 thioesterase superfamilyl protein YP_002988059.1 PFAM: nitroreductase; KEGG: eca:ECA2838 hypothetical protein YP_002988060.1 PFAM: flavodoxin/nitric oxide synthase; KEGG: ecz:ECS88_3009 protein with flavodoxin fold YP_002988061.1 KEGG: ent:Ent638_2231 hypothetical protein YP_002988062.1 PFAM: protein of unknown function DUF980; KEGG: eca:ECA1680 hypothetical protein YP_002988063.1 PFAM: integrase family protein; KEGG: eca:ECA2889 integrase YP_002988064.1 PFAM: major facilitator superfamily MFS_1; KEGG: bcm:Bcenmc03_5732 EmrB/QacA family drug resistance transporter YP_002988065.1 KEGG: pat:Patl_3304 NAD-dependent epimerase/dehydratase YP_002988066.1 KEGG: rpi:Rpic_0461 hypothetical protein YP_002988067.1 PFAM: Integrase catalytic region; KEGG: son:SO_A0151 ISSod13, transposase YP_002988068.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pmr:PMI1178 AraC-family transcriptional regulator YP_002988069.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: kpe:KPK_2659 drug resistance MFS transporter drug:H+ antiporter-1 (DHA2) family YP_002988070.1 PFAM: secretion protein HlyD; KEGG: kpe:KPK_2660 auxiliary transporter, membrane fusion protein (MFP) family YP_002988071.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: kpe:KPK_2661 MarR family transcriptional regulator YP_002988072.1 PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: eca:ECA1568 chemotaxis signal transduction protein YP_002988073.1 PFAM: hypothetical protein; KEGG: esa:ESA_04136 hypothetical protein YP_002988074.1 KEGG: oca:OCAR_4559 hypothetical protein YP_002988075.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0183 methyl-accepting chemotaxis protein YP_002988076.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: stm:STM3698 permease YP_002988077.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: stm:STM3697 mandelate racemase YP_002988078.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: eca:ECA0997 LacI family transcriptional regulator YP_002988080.1 KEGG: eca:ECA3371 hypothetical protein YP_002988081.1 PFAM: glycosyl transferase family 28; KEGG: bte:BTH_II1880 rhamnosyltransferase I, subunit B YP_002988082.1 KEGG: eca:ECA4379 gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_002988083.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: eca:ECA1497 two-component system response regulator protein YP_002988084.1 KEGG: eca:ECA1496 two-component system sensor histidine kinase; PFAM: MASE1 domain protein; ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein YP_002988085.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1495 regulatory protein YP_002988086.1 PFAM: extracellular solute-binding protein family 1; KEGG: yen:YE2659 extracellular solute-binding protein YP_002988087.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1493 ferric ABC transporter permease YP_002988088.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import YP_002988089.1 PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; SMART: chemotaxis sensory transducer; KEGG: bph:Bphy_5545 methyl-accepting chemotaxis sensory transducer YP_002988090.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ent:Ent638_1967 LysR family transcriptional regulator YP_002988091.1 catalyzes the transfer of an amino moiety YP_002988092.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: ent:Ent638_1970 extracellular solute-binding protein YP_002988093.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA2989 uroporphyrin-III C-methyltransferase YP_002988094.1 PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; molydopterin dinucleotide-binding region; KEGG: eca:ECA2990 nitrate reductase YP_002988095.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eca:ECA2991 nitrite reductase [NAD(P)H] large subunit YP_002988096.1 KEGG: eca:ECA2992 nitrate transporter; TIGRFAM: nitrate ABC transporter ATPases C and D; PFAM: ABC transporter related; SMART: ATPase AAA YP_002988097.1 TIGRFAM: nitrate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2993 nitrate transporter permease YP_002988098.1 KEGG: eca:ECA2994 nitrate-binding proteint YP_002988099.1 TIGRFAM: formyl-CoA transferase; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pol:Bpro_2803 formyl-coenzyme A transferase YP_002988100.1 KEGG: mch:Mchl_1366 PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein YP_002988101.1 TIGRFAM: formyl-CoA transferase; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pol:Bpro_2801 formyl-coenzyme A transferase YP_002988102.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_002988103.1 PFAM: major facilitator superfamily MFS_1; KEGG: cti:RALTA_B1242 transporter; major facilitator superfamily MFS_1 YP_002988104.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sew:SeSA_A2659 OsmT protein YP_002988105.1 KEGG: pfl:PFL_2675 lipoprotein YP_002988106.1 PFAM: protein of unknown function UPF0157; KEGG: kpn:KPN_01720 hypothetical protein YP_002988107.1 PFAM: nitrate and nitrite sensing domain protein; ANTAR domain protein; KEGG: eca:ECA2995 nitrate-and nitrite-responsive positive regulator YP_002988108.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA2712 methyl-accepting chemotaxis protein YP_002988109.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: spe:Spro_2477 RND efflux system outer membrane lipoprotein YP_002988110.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yen:YE0444 multidrug efflux protein YP_002988111.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: yen:YE0443 multidrug efflux protein YP_002988112.1 PFAM: regulatory protein TetR; KEGG: spe:Spro_1191 TetR family transcriptional regulator YP_002988113.1 TIGRFAM: drug resistance transporter Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_1190 Bcr/CflA subfamily drug resistance transporter YP_002988114.1 required for the formation of active formate dehydrogenase YP_002988116.1 cytochrome b556(FDO) component; heme containing YP_002988117.1 TIGRFAM: formate dehydrogenase subunit beta; PFAM: formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: spe:Spro_0085 formate dehydrogenase, subunit beta YP_002988118.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: eca:ECA1408 formate dehydrogenase, nitrate-inducible, major subunit YP_002988119.1 PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA3004 transcription regulator GntR YP_002988120.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002988121.1 KEGG: eca:ECA3006 hypothetical protein YP_002988122.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: yen:YE3600 hydrogenase maturation protein YP_002988123.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: pmr:PMI0040 hydrogenase formation protein YP_002988124.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: pmr:PMI0039 hydrogenase formation protein YP_002988125.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: yen:YE3602A hydrogenase 2 accessory protein HypG YP_002988126.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: pmr:PMI0037 hydrogenase nickel incorporation protein YP_002988127.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis HypA; KEGG: yen:YE3603a hydrogenase nickel incorporation protein HybF YP_002988128.1 KEGG: yen:YE3604 hydrogenase 2-specific chaperone YP_002988129.1 TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: yen:YE3605 hydrogenase 2 maturation endopeptidase YP_002988130.1 involved in hydrogen uptake YP_002988131.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_002988132.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_002988133.1 involved in hydrogen uptake YP_002988134.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3010 ABC transporter ATP-binding protein YP_002988135.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: eca:ECA3011 hypothetical protein YP_002988137.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988138.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988139.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002988140.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988141.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; KEGG: eta:ETA_12120 NADH dehydrogenase I chain J YP_002988142.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988143.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988144.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988145.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_002988146.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: eca:ECA3025 NADH dehydrogenase subunit E YP_002988147.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_002988148.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002988149.1 Catalyzes the transfer of electrons from NADH to quinone YP_002988150.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3032 LysR family transcriptional regulator YP_002988152.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002988153.1 KEGG: eca:ECA3034 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_002988154.1 PFAM: citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: eca:ECA3035 sodium/sulfate transporter YP_002988155.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA3036 phosphatase YP_002988156.1 PFAM: YfbU family protein; KEGG: eca:ECA3037 hypothetical protein YP_002988157.1 PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein YP_002988158.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002988159.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002988160.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA3042 NUDIX hydrolase YP_002988161.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: eca:ECA3043 phosphodiesterase YP_002988162.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA3044 glutathione-S transferase YP_002988163.1 PFAM: hypothetical protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA3046 hypothetical protein YP_002988164.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3047 histidine/lysine/arginine/ornithine transporter subunit YP_002988165.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3048 histidine ABC transporter permease YP_002988166.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3049 histidine ABC transporter permease YP_002988167.1 KEGG: eca:ECA3050 histidine-binding periplasmic protein; TIGRFAM: cationic amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_002988168.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: yen:YE1317 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002988169.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002988170.1 membrane protein required for colicin V production YP_002988171.1 PFAM: sporulation domain protein; KEGG: eca:ECA3054 hypothetical protein YP_002988172.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: eca:ECA3055 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_002988173.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002988174.1 PFAM: SNARE associated Golgi protein; KEGG: spe:Spro_3333 hypothetical protein YP_002988175.1 KEGG: eca:ECA3058 tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase YP_002988176.1 PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; KEGG: eca:ECA3059 semialdehyde dehydrogenase YP_002988177.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: esa:ESA_00896 hypothetical protein YP_002988178.1 PFAM: Two-component sensor kinase domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: spe:Spro_3339 integral membrane sensor signal transduction histidine kinase YP_002988179.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: plu:plu3179 two-component response regulator YP_002988180.1 PFAM: conserved hypothetical protein; KEGG: ses:SARI_00189 hypothetical protein YP_002988181.1 KEGG: ses:SARI_00188 hypothetical protein YP_002988182.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: spe:Spro_3344 hypothetical protein YP_002988183.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_002988184.1 PFAM: beta-ketoacyl synthase; KEGG: eca:ECA3063 3-oxoacyl-(acyl carrier protein) synthase I YP_002988185.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002988186.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA3245 methyl-accepting chemotaxis protein YP_002988187.1 KEGG: eca:ECA3244 hypothetical protein YP_002988188.1 PFAM: YfcL protein; KEGG: kpe:KPK_1424 hypothetical protein YP_002988189.1 PFAM: protein of unknown function DUF462; KEGG: spe:Spro_3371 hypothetical protein YP_002988190.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA3067 hypothetical protein YP_002988191.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_002988192.1 KEGG: eca:ECA3069 chorismate synthase; TIGRFAM: chorismate synthase; PFAM: chorismate synthase YP_002988193.1 KEGG: eca:ECA3070 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small YP_002988194.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: eca:ECA3071 hypothetical protein YP_002988195.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: phosphoglycerate mutase; KEGG: eca:ECA3072 phosphohistidine phosphatase YP_002988196.1 TIGRFAM: fatty acid oxidation complex, subunit alpha FadJ; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3078 multifunctional fatty acid oxidation complex subunit alpha YP_002988197.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002988198.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3080 hypothetical protein YP_002988199.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: eca:ECA3081 long-chain fatty acid outer membrane transporter YP_002988200.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002988201.1 PFAM: VacJ family lipoprotein; KEGG: eca:ECA3083 lipoprotein YP_002988202.1 PFAM: methyltransferase type 11; KEGG: NMT1; NMT1 (N-METHYLTRANSFERASE 1); phosphoethanolamine N-methyltransferase YP_002988203.1 KEGG: sei:SPC_4455 hypothetical protein YP_002988204.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns YP_002988205.1 PFAM: regulatory protein TetR; KEGG: bur:Bcep18194_B0583 TetR family transcriptional regulator YP_002988207.1 KEGG: eca:ECA3166 hypothetical protein YP_002988209.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; alternative NifH, may be molybdenum-independent YP_002988210.1 TIGRFAM: nitrogenase alpha chain; nitrogenase component I, alpha chain; nitrogenase iron-iron protein, alpha chain; PFAM: oxidoreductase/nitrogenase component 1; KEGG: rru:Rru_A1394 nitrogenase iron-iron protein, alpha chain YP_002988211.1 KEGG: rru:Rru_A1393 nitrogenase; TIGRFAM: Fe-only nitrogenase, subunit delta; PFAM: Vanadium/alternative nitrogenase delta subunit YP_002988212.1 KEGG: rru:Rru_A1392 nitrogenase; TIGRFAM: Fe-only nitrogenase subunit beta; PFAM: oxidoreductase/nitrogenase component 1 YP_002988213.1 KEGG: dal:Dalk_1513 hypothetical protein YP_002988214.1 KEGG: rpa:RPA1432 nitroimidazole resistance protein YP_002988215.1 TIGRFAM: Fe-only nitrogenase accessory protein AnfO; KEGG: rpt:Rpal_1619 Fe-only nitrogenase accessory protein AnfO YP_002988216.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: GAF domain protein; ATPase AAA; KEGG: rpa:RPA1374 sigma-54 dependent, vanadium nitrogenase transcriptional regulator, VnfA YP_002988217.1 PFAM: inosine/uridine-preferring nucleoside hydrolase; KEGG: ara:Arad_9875 inosine-uridine preferring nucleoside hydrolase protein YP_002988218.1 KEGG: bxe:Bxe_C0823 tetrahydrodipicolinate N-succinyltransferase YP_002988219.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: eca:ECA1475 hypothetical protein YP_002988220.1 KEGG: kpe:KPK_1527 hypothetical protein YP_002988221.1 PFAM: methyltransferase type 11; KEGG: afw:Anae109_1351 methyltransferase type 11 YP_002988222.1 PFAM: gamma-glutamyltranspeptidase; KEGG: ent:Ent638_0756 gamma-glutamyltransferase YP_002988223.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ent:Ent638_0755 binding-protein-dependent transport systems inner membrane component YP_002988224.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ent:Ent638_0754 binding-protein-dependent transport systems inner membrane component YP_002988225.1 PFAM: extracellular solute-binding protein family 5; KEGG: ent:Ent638_0753 extracellular solute-binding protein YP_002988226.1 KEGG: ent:Ent638_0752 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002988227.1 KEGG: ent:Ent638_0751 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002988228.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: ent:Ent638_0750 GntR family transcriptional regulator YP_002988229.1 PFAM: nucleoside recognition domain protein; KEGG: kpe:KPK_4862 transporter gate domain protein YP_002988230.1 PFAM: nucleoside recognition domain protein; KEGG: kpe:KPK_4861 transporter gate domain protein YP_002988231.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: kpe:KPK_4860 amidohydrolase family protein YP_002988232.1 PFAM: regulatory protein TetR; KEGG: acr:Acry_3038 TetR family transcriptional regulator YP_002988233.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: plu:plu4115 glycerol dehydrogenase YP_002988234.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: efe:EFER_1525 enolase/dehydratase YP_002988235.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: eca:ECA0918 dehydrogenase YP_002988236.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA0919 transporter YP_002988237.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0920 carbohydrate oxidoreductase YP_002988238.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0921 GntR family transcriptional regulator YP_002988239.1 KEGG: smd:Smed_0204 hypothetical protein YP_002988240.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002988241.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002988242.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: reu:Reut_A2718 ABC transporter YP_002988243.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: cti:RALTA_A2495 ABC-type transporter membrane component YP_002988244.1 PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3; KEGG: rme:Rmet_2859 substrate-binding region of ABC-type glycine betaine transporter YP_002988245.1 PFAM: peptidase S14 ClpP; KEGG: mes:Meso_1336 peptidase S14, ClpP YP_002988246.1 KEGG: spe:Spro_2078 histidine utilization repressor; TIGRFAM: histidine utilization repressor; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH YP_002988247.1 KEGG: kpe:KPK_3142 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase YP_002988248.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: kpe:KPK_3143 amino acid ABC transporter ATP-binding protein YP_002988249.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpe:KPK_3144 amino acid ABC transporter permease YP_002988250.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpe:KPK_3145 amino acid ABC transporter permease YP_002988251.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: kpe:KPK_3146 amino acid ABC transporter periplasmic amino acid-binding protein YP_002988252.1 PFAM: protein of unknown function DUF886; KEGG: esa:ESA_02151 hypothetical protein YP_002988253.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_002988254.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002988255.1 TIGRFAM: N-formylglutamate amidohydrolase; PFAM: N-formylglutamate amidohydrolase; KEGG: spe:Spro_2076 N-formylglutamate amidohydrolase YP_002988256.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; nitrate and nitrite sensing domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA0434 methyl-accepting chemotaxis protein YP_002988257.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002988258.1 KEGG: eca:ECA3150 hypothetical protein YP_002988259.1 KEGG: ent:Ent638_0980 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia ; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M) YP_002988260.1 PFAM: DoxX family protein; KEGG: eca:ECA3152 hypothetical protein YP_002988261.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: eca:ECA3154 peptidyl-prolyl cis-trans isomerase B (rotamase B) YP_002988262.1 TIGRFAM: UDP-2,3-diacylglucosamine hydrolase; PFAM: metallophosphoesterase; KEGG: eca:ECA3155 UDP-2,3-diacylglucosamine hydrolase YP_002988263.1 KEGG: eca:ECA3156 phosphoribosylaminoimidazole carboxylase catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_002988264.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002988265.1 TIGRFAM: serine transporter; PFAM: aromatic amino acid permease; Spore germination protein; KEGG: eca:ECA3158 serine transporter YP_002988266.1 KEGG: eca:ECA3159 L-serine dehydratase 2; TIGRFAM: L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_002988267.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3160 transcriptional regulator YP_002988268.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002988269.1 TIGRFAM: phosphate ABC transporter inner membrane subunit PstA; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3162 phosphate ABC transporter permease YP_002988270.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3163 phosphate ABC transporter permease protein YP_002988271.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002988272.1 PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase YP_002988273.1 KEGG: esa:ESA_00757 hypothetical protein YP_002988274.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: kpe:KPK_3736 C4-type hypothetical protein, DksA/TraR family YP_002988275.1 PFAM: UspA domain protein; KEGG: eca:ECA1769 hypothetical protein YP_002988276.1 KEGG: elf:LF82_3563 uncharacterized protein YneG YP_002988277.1 PFAM: isochorismatase hydrolase; KEGG: yen:YE3592 isochorismatase family protein YP_002988278.1 KEGG: abu:Abu_0659 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase ; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_002988279.1 TIGRFAM: methyltransferase FkbM family; KEGG: mfa:Mfla_0764 methyltransferase FkbM YP_002988280.1 PFAM: glycosyl transferase group 1; KEGG: bha:BH1415 hypothetical protein YP_002988281.1 PFAM: glycosyl transferase group 1; KEGG: pla:Plav_2494 glycosyl transferase group 1 YP_002988282.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: xfn:XfasM23_2056 ABC transporter YP_002988283.1 PFAM: ABC transporter; KEGG: xfm:Xfasm12_2139 ABC transporter permease YP_002988284.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: met:M446_4668 NAD-dependent epimerase/dehydratase YP_002988285.1 PFAM: protein of unknown function UPF0005; KEGG: eca:ECA1763 hypothetical protein YP_002988286.1 TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; KEGG: ypi:YpsIP31758_2529 sulfurtransferase TusE YP_002988287.1 PFAM: acylphosphatase; KEGG: ypg:YpAngola_A3210 acylphosphatase YP_002988288.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: eca:ECA1760 hypothetical protein YP_002988289.1 PFAM: CoA-binding protein; KEGG: eca:ECA1759 CoA binding protein YP_002988290.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002988291.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002988292.1 PFAM: protein of unknown function DUF307; KEGG: efe:EFER_1098 conserved hypothetical protein; inner membrane protein YP_002988293.1 TIGRFAM: hypothetical protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: eca:ECA1754 hypothetical protein YP_002988294.1 PFAM: Integrase catalytic region; KEGG: son:SO_A0151 ISSod13, transposase YP_002988295.1 PFAM: TfoX domain protein; KEGG: eca:ECA1753 hypothetical protein YP_002988296.1 PFAM: cell division inhibitor SulA; KEGG: eca:ECA1752 SOS cell division inhibitor YP_002988297.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_002988299.1 PFAM: aldo/keto reductase; KEGG: eca:ECA3182 oxidoreductase YP_002988300.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: spe:Spro_3416 nucleoside transporter YP_002988301.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002988302.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002988303.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_002988304.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3187 multidrug efflux system protein MdtE YP_002988305.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eca:ECA3188 signal transduction histidine-protein kinase BaeS YP_002988306.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_002988307.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA3192 hypothetical protein YP_002988308.1 PFAM: peptidase U32; KEGG: eca:ECA3193 protease YP_002988309.1 PFAM: phosphate-starvation-inducible E; KEGG: eca:ECA3195 phosphate-starvation-inducible protein PsiE YP_002988310.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002988311.1 KEGG: eca:ECA3197 hydroxyethylthiazole kinase; TIGRFAM: hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase YP_002988312.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA3501 hypothetical protein YP_002988313.1 KEGG: esa:ESA_02629 hypothetical protein YP_002988314.1 KEGG: hypothetical protein YP_002988316.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: xac:XAC0539 short chain dehydrogenase YP_002988317.1 KEGG: xac:XAC0537 hypothetical protein YP_002988318.1 KEGG: eca:ECA3203 hypothetical protein YP_002988319.1 KEGG: ent:Ent638_0388 hypothetical protein YP_002988320.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: bch:Bcen2424_3293 (acyl-carrier-protein) phosphodiesterase YP_002988321.1 KEGG: bcm:Bcenmc03_1718 hypothetical protein YP_002988322.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bch:Bcen2424_6323 AraC family transcriptional regulator YP_002988323.1 PFAM: hypothetical protein; KEGG: pna:Pnap_4045 hypothetical protein YP_002988324.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: mag:amb2954 signal transduction histidine kinase YP_002988325.1 PFAM: metal-dependent hydrolase HDOD; response regulator receiver; SMART: response regulator receiver; KEGG: smt:Smal_3319 signal transduction protein YP_002988326.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: sat:SYN_01373 hydrogenase transcriptional regulatory protein YP_002988327.1 TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; KEGG: eca:ECA3208 bifunctional GMP synthase/glutamine amidotransferase protein YP_002988328.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002988329.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002988330.1 PFAM: peptidase M4 thermolysin; peptidase M4 thermolysin; KEGG: eca:ECA3211 extracellular metalloprotease YP_002988331.1 PFAM: protein of unknown function DUF1407; KEGG: spe:Spro_3603 hypothetical protein YP_002988332.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002988333.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_002988334.1 KEGG: eca:ECA3218 hypothetical protein YP_002988335.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002988336.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002988337.1 SMART: helix-turn-helix domain protein; KEGG: eca:ECA3221 hypothetical protein YP_002988338.1 KEGG: eca:ECA3222 hypothetical protein; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; hypotheticalprotein; SMART: Tetratricopeptide domain protein YP_002988339.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002988340.1 KEGG: plu:plu1372 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase YP_002988341.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_002988342.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_002988343.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002988344.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: stm:STM2537 hypothetical protein YP_002988345.1 TIGRFAM: ferredoxin 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: cko:CKO_00256 hypothetical protein YP_002988346.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002988347.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002988348.1 TIGRFAM: iron-sulfur cluster assembly protein IscA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: yen:YE1059 iron-sulfur cluster assembly protein YP_002988349.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: eca:ECA3236 scaffold protein YP_002988350.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002988351.1 regulates the expression of the iscRSUA operon YP_002988352.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: eca:ECA3239 RNA methyltransferase YP_002988353.1 PFAM: inositol monophosphatase; KEGG: eca:ECA3240 inositol monophosphatase YP_002988354.1 KEGG: eca:ECA3241 ABC transporter substrate-binding protein YP_002988355.1 PFAM: transporter permease; KEGG: eca:ECA3242 ABC transporter permease YP_002988356.1 PFAM: ABC transporter; SMC domain protein; SMART: ATPase AAA; KEGG: eca:ECA3243 ferric-enterobactin ABC transporter ATP-binding protein YP_002988357.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3246 periplasmic substrate-binding transporter YP_002988358.1 PFAM: high-affinity nickel-transporter; KEGG: eca:ECA3247 hypothetical protein YP_002988359.1 PFAM: protein of unknown function DUF1007; KEGG: eca:ECA3248 hypothetical protein YP_002988360.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_002988361.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002988362.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: xac:XAC3562 pectate lyase YP_002988363.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: xac:XAC3562 pectate lyase YP_002988364.1 PFAM: lipolytic protein G-D-S-L family; KEGG: eca:ECA3252 pectin acetylesterase YP_002988365.1 PFAM: pectinesterase; KEGG: eca:ECA3253 pectinesterase A YP_002988366.1 PFAM: nitrogen regulatory protein P-II; KEGG: eta:ETA_10110 nitrogen regulatory protein P-II YP_002988367.1 PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; ATPase AAA; KEGG: eca:ECA3255 two-component system response regulator YP_002988368.1 KEGG: eca:ECA3256 hypothetical protein YP_002988369.1 PFAM: ATP-binding region ATPase domain protein; fimbrial assembly family protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA3257 two-component system sensor kinase YP_002988370.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002988371.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_002988372.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: eca:ECA3260 tRNA-specific adenosine deaminase YP_002988373.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: eca:ECA3261 hypothetical protein YP_002988374.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002988375.1 KEGG: eca:ECA3265 hypothetical protein YP_002988376.1 KEGG: eca:ECA3268 toxin secretion ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_002988377.1 KEGG: eca:ECA3270 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein YP_002988378.1 in Escherichia coli this protein is involved in flagellar function YP_002988379.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yen:YE1024 [4Fe-4S] ferredoxin YP_002988380.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002988381.1 KEGG: eca:ECA3275 pyridoxal phosphate biosynthetic protein PdxJ; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: pyridoxal phosphate biosynthetic protein PdxJ YP_002988382.1 TIGRFAM: DNA repair protein RecO; PFAM: recombination protein O RecO; KEGG: yen:YE1019 DNA repair protein RecO YP_002988383.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002988384.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002988385.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_002988386.1 TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; PFAM: GTP-binding protein LepA domain protein; elongation factor G domain protein; elongation factor Tu domain 2 protein; protein synthesis factor GTP-binding; KEGG: eca:ECA3280 GTP-binding protein LepA YP_002988387.1 involved in the reduction of the SoxR iron-sulfur cluster YP_002988388.1 PFAM: MucB/RseB family protein; KEGG: spe:Spro_3674 periplasmic negative regulator of sigmaE YP_002988389.1 PFAM: anti sigma-E protein RseA family protein; anti sigma-E protein RseA domain protein; KEGG: eca:ECA3283 anti-RNA polymerase sigma factor SigE YP_002988390.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002988391.1 TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein; KEGG: yen:YE1009 L-aspartate oxidase YP_002988392.1 PFAM: methyltransferase small; KEGG: eca:ECA3286 hypothetical protein YP_002988393.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002988394.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_002988395.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002988396.1 KEGG: pfl:PFL_0498 O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_002988397.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002988398.1 PFAM: DoxX family protein; KEGG: eca:ECA3295 hypothetical protein YP_002988399.1 KEGG: eca:ECA3296 sulfate ABC transporter ATP-binding protein; TIGRFAM: sulfate ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_002988400.1 TIGRFAM: sulfate ABC transporter inner membrane subunit CysW; sulfate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3297 sulfate ABC transporter permease YP_002988401.1 TIGRFAM: sulfate ABC transporter inner membrane subunit CysT; sulfate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3298 sulfate ABC transporter permease YP_002988402.1 TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3299 sulfate-binding protein YP_002988403.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_002988404.1 protease Do; required at high temperature; degrades damaged proteins YP_002988405.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_002988406.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002988407.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3304 vitamin B12-transporter protein BtuF YP_002988408.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: spe:Spro_0783 iron-sulfur cluster assembly accessory protein YP_002988409.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_002988410.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002988411.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002988412.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_002988413.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_002988414.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_002988415.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002988416.1 TIGRFAM: 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; KEGG: eca:ECA3315 2'-5' RNA ligase YP_002988417.1 TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; KEGG: eca:ECA3316 sugar fermentation stimulation protein A YP_002988418.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: kpn:KPN_00145 DnaK transcriptional regulator DksA YP_002988419.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: esa:ESA_03196 glutamyl-Q tRNA(Asp) synthetase YP_002988420.1 polymerase that creates the 3' poly(A) tail found in some mRNA's YP_002988421.1 KEGG: eca:ECA3320 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_002988422.1 KEGG: eca:ECA3321 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase YP_002988423.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002988424.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002988425.1 PFAM: ABC transporter; KEGG: spe:Spro_3995 ABC-2 type transporter YP_002988426.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: yen:YE0715 ABC transporter ATP-binding protein YP_002988427.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_002988428.1 KEGG: eca:ECA3328 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_002988429.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3329 acetyltransferase YP_002988430.1 KEGG: asa:ASA_3604 hypothetical protein YP_002988431.1 KEGG: asa:ASA_3605 hypothetical protein YP_002988432.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: eca:ECA3330 ATP transporter ATP-binding protein YP_002988433.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3331 ABC transporter permease YP_002988434.1 KEGG: eca:ECA3332 hypothetical protein YP_002988435.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002988436.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002988437.1 3'-5' exonuclease of DNA polymerase III YP_002988438.1 PFAM: ribonuclease H; KEGG: spe:Spro_0911 ribonuclease H YP_002988439.1 PFAM: methyltransferase type 11; KEGG: spe:Spro_0910 methyltransferase type 11 YP_002988440.1 KEGG: eca:ECA3342 hydroxyacylglutathione hydrolase; TIGRFAM: hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein YP_002988441.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_002988442.1 KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_002988443.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: eca:ECA3344 hypothetical protein YP_002988444.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_002988445.1 KEGG: eca:ECA3345 protein disaggregation chaperone; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; ATPase AAA; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA YP_002988446.1 PFAM: protein of unknown function DUF152; KEGG: eca:ECA3346 hypothetical protein YP_002988447.1 KEGG: eca:ECA3347 23S rRNA pseudouridine synthase D; TIGRFAM: pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein YP_002988448.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_002988449.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: cko:CKO_03918 translation inhibitor protein RaiA YP_002988450.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002988451.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002988452.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002988453.1 KEGG: eca:ECA3354 hypothetical protein YP_002988454.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002988455.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002988456.1 Essential for efficient processing of 16S rRNA YP_002988457.1 TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: eca:ECA3359 30S ribosomal protein S16 YP_002988458.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_002988459.1 PFAM: cytochrome C assembly protein; KEGG: eca:ECA3361 hypothetical protein YP_002988460.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_06534 hypothetical protein YP_002988461.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: eca:ECA1161 ammonium transporter YP_002988462.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_002988463.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: spe:Spro_1108 multidrug transporter membrane\ATP-binding components YP_002988464.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: eca:ECA1158 multidrug transporter membrane\ATP-binding components YP_002988465.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: eca:ECA1157 transcription regulator AsnC YP_002988466.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eca:ECA1156 pyridoxal-phosphate dependent protein YP_002988467.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: eca:ECA1155 queuosine biosynthesis protein QueC YP_002988468.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: eca:ECA1153 hypothetical protein YP_002988469.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: eca:ECA1152 peptidyl-prolyl cis-trans isomerase (rotamase D) YP_002988470.1 histone-like DNA-binding protein YP_002988471.1 KEGG: eca:ECA1150 DNA-binding ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16; ATPase AAA YP_002988472.1 binds and unfolds substrates as part of the ClpXP protease YP_002988473.1 KEGG: eca:ECA1148 ATP-dependent Clp protease proteolytic subunit; TIGRFAM: ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: peptidase S14 ClpP YP_002988475.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002988476.1 PFAM: BolA family protein; KEGG: eca:ECA1146 transcriptional regulator BolA YP_002988477.1 PFAM: Uncharacterized lipoprotein; KEGG: spe:Spro_1092 hypothetical protein YP_002988478.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_002988479.1 TIGRFAM: ubiquinol oxidase subunit II; PFAM: COX aromatic rich domain protein; cytochrome C oxidase subunit II; KEGG: eca:ECA1143 cytochrome o ubiquinol oxidase subunit II YP_002988480.1 KEGG: eca:ECA1142 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome C oxidase subunit I YP_002988481.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome C oxidase subunit III; KEGG: eca:ECA1141 cytochrome o ubiquinol oxidase subunit III YP_002988482.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: eca:ECA1140 cytochrome o ubiquinol oxidase subunit IV YP_002988483.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002988484.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA1138 transporter YP_002988485.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002988486.1 Ketopantoate reductase; catalyzes the NADPH reduction of Ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002988487.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA1135 hypothetical protein YP_002988488.1 Required for the synthesis of the thiazole moiety YP_002988489.1 TIGRFAM: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; KEGG: eca:ECA1133 exodeoxyribonuclease VII small subunit YP_002988490.1 PFAM: polyprenyl synthetase; KEGG: eca:ECA1132 geranyltranstransferase YP_002988491.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002988492.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002988493.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002988494.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002988495.1 KEGG: eca:ECA1127 riboflavin synthase subunit beta; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase YP_002988496.1 KEGG: eca:ECA1126 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding YP_002988497.1 PFAM: ATP-cone domain protein; KEGG: sgl:SG0650 transcriptional regulator NrdR YP_002988498.1 P-type ATPase involved in magnesium influx YP_002988499.1 KEGG: eca:ECA1124 hypothetical protein YP_002988500.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002988501.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002988502.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: eum:ECUMN_0445 SecYEG protein translocase auxillary subunit YP_002988503.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002988504.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002988505.1 PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein YP_002988506.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: yen:YE3174 alkyl hydroperoxide reductase subunit C YP_002988507.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_002988508.1 TIGRFAM: branched-chain amino acid transporter II carrier protein; PFAM: branched-chain amino acid transporter II carrier protein; KEGG: eca:ECA1114 branched-chain amino acid transporter II carrier protein YP_002988509.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_002988510.1 TIGRFAM: phosphate binding protein; KEGG: eca:ECA1112 phosphate binding protein YP_002988511.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002988512.1 KEGG: eca:ECA1110 phosphate regulon response regulator; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver YP_002988513.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: eca:ECA1109 exonuclease subunit SbcD YP_002988514.1 PFAM: SMC domain protein; KEGG: eca:ECA1108 exonuclease YP_002988515.1 PFAM: ROK family protein; KEGG: eca:ECA1107 fructokinase YP_002988516.1 PFAM: exonuclease RdgC; KEGG: spe:Spro_1027 recombination associated protein YP_002988517.1 PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1105 methyl-accepting chemotaxis protein YP_002988518.1 PFAM: protein of unknown function DUF1255; KEGG: eca:ECA1104 hypothetical protein YP_002988519.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002988521.1 KEGG: eca:ECA1102 L-asparaginase precursor; TIGRFAM: L-asparaginase, type II; PFAM: asparaginase/glutaminase YP_002988522.1 efflux pump for the antibacterial peptide microcin J25 YP_002988523.1 PFAM: methionine synthase vitamin-B12 independent; KEGG: bsu:BSU38960 hypothetical protein YP_002988524.1 TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: haloacid dehalogenase; KEGG: spe:Spro_1624 HAD family hydrolase YP_002988525.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2075 LysR family transcriptional regulator YP_002988526.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: eca:ECA2074 hypothetical protein YP_002988527.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: bpy:Bphyt_5120 major facilitator superfamily MFS_1 YP_002988528.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0956 acetyltransferase YP_002988530.1 KEGG: eca:ECA3090 hypothetical protein YP_002988531.1 PFAM: stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: eca:ECA1089 hypothetical protein YP_002988532.1 KEGG: eca:ECA1088 hypothetical protein YP_002988533.1 KEGG: eca:ECA1087 lipoprotein YP_002988534.1 KEGG: eca:ECA1086 signaling protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_002988535.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: eca:ECA1082 phosphonoacetate hydrolase YP_002988537.1 PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: mmw:Mmwyl1_3284 major facilitator transporter YP_002988538.1 KEGG: eca:ECA1067 hypothetical protein YP_002988539.1 KEGG: ent:Ent638_2896 hypothetical protein YP_002988540.1 PFAM: Relaxase/mobilization nuclease family protein; KEGG: ecr:ECIAI1_4511 hypothetical protein YP_002988541.1 KEGG: cko:CKO_03957 hypothetical protein YP_002988543.1 KEGG: yen:YE0987 inner membrane protein YP_002988544.1 KEGG: cko:CKO_03959 hypothetical protein YP_002988545.1 KEGG: cko:CKO_03960 hypothetical protein YP_002988546.1 KEGG: cko:CKO_03961 hypothetical protein YP_002988547.1 PFAM: integrase family protein; KEGG: cko:CKO_03962 hypothetical protein YP_002988548.1 PFAM: integrase family protein; KEGG: ecr:ECIAI1_4503 integrase YP_002988549.1 KEGG: bmu:Bmul_3996 hypothetical protein YP_002988550.1 PFAM: UvrD/REP helicase; KEGG: sde:Sde_0195 UvrD/REP helicase family protein YP_002988551.1 KEGG: ppr:PBPRC0043 exonuclease YP_002988552.1 KEGG: eca:ECA1058 hypothetical protein YP_002988553.1 PFAM: integrase family protein; KEGG: ecw:EcE24377A_3028 phage integrase family protein YP_002988554.1 This protein performs the mismatch recognition step during the DNA repair process YP_002988555.1 KEGG: eca:ECA1052 lipoprotein involved with copper homeostasis and adhesion YP_002988556.1 PFAM: YaeQ family protein; KEGG: eca:ECA1051 hypothetical protein YP_002988557.1 PFAM: protein of unknown function UPF0253; KEGG: spe:Spro_3762 hypothetical protein YP_002988558.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_002988559.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_002988560.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA1048 hypothetical protein YP_002988561.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002988562.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002988563.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002988564.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_002988565.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002988566.1 TIGRFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: pmr:PMI2274 (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase YP_002988567.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002988568.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: eca:ECA1040 periplasmic chaperone YP_002988569.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_002988570.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_002988571.1 PFAM: phosphatidate cytidylyltransferase; KEGG: eca:ECA1037 CDP-diglyceride synthase YP_002988572.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: eca:ECA1036 undecaprenyl pyrophosphate synthetase YP_002988574.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002988575.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002988576.1 Catalyzes the phosphorylation of UMP to UDP YP_002988577.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002988578.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002988579.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: eta:ETA_08880 methionine aminopeptidase YP_002988580.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002988581.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002988582.1 KEGG: eum:ECUMN_0161 hypothetical protein YP_002988583.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002988584.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002988585.1 PFAM: protein of unknown function DUF446; KEGG: eca:ECA1024 hypothetical protein YP_002988586.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002988587.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1019 lysine decarboxylase family protein YP_002988588.1 PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: eca:ECA1018 exonuclease IX YP_002988589.1 KEGG: eca:ECA1017 RNA 2'-O-ribose methyltransferase YP_002988590.1 PFAM: protein of unknown function DUF423; KEGG: eca:ECA1016 hypothetical protein YP_002988591.1 glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002988592.1 PFAM: protein of unknown function DUF903; KEGG: eca:ECA1013 lipoprotein YP_002988593.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: eca:ECA1012 cysteine sulfinate desulfinase YP_002988594.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: eca:ECA1011 Fe-S metabolism associated protein YP_002988595.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: eca:ECA1010 hypothetical protein YP_002988596.1 PFAM: GCN5-related N-acetyltransferase; KEGG: swd:Swoo_4463 GCN5-related N-acetyltransferase YP_002988597.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: asa:ASA_0954 D-3-phosphoglycerate dehydrogenase YP_002988598.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sse:Ssed_0582 GCN5-related N-acetyltransferase YP_002988599.1 PFAM: GCN5-related N-acetyltransferase; KEGG: spc:Sputcn32_1266 GCN5-related N-acetyltransferase YP_002988600.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002988601.1 KEGG: eca:ECA1000 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin YP_002988602.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002988603.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002988604.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002988605.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA0994 protease III precursor YP_002988606.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002988607.1 KEGG: eca:ECA0992 prepilin peptidase dependent protein c precursor YP_002988608.1 KEGG: eca:ECA0991 hypothetical protein YP_002988609.1 KEGG: eca:ECA0990 hypothetical protein YP_002988610.1 KEGG: eca:ECA0989 hypothetical protein YP_002988611.1 KEGG: spe:Spro_3821 thymidylate synthase; TIGRFAM: thymidylate synthase; PFAM: thymidylate synthase YP_002988612.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002988613.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002988614.1 hydrolyzes diadenosine polyphosphate YP_002988615.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002988616.1 PFAM: integral membrane protein TerC; KEGG: eca:ECA0983 hypothetical protein YP_002988617.1 PFAM: protein of unknown function DUF903; KEGG: eca:ECA0982 lipoprotein YP_002988618.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_002988619.1 KEGG: eca:ECA0979 hypothetical protein YP_002988620.1 PFAM: protein of unknown function DUF469; KEGG: eca:ECA0978 hypothetical protein YP_002988621.1 KEGG: eca:ECA0977 tRNA (guanine-N(7))-methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase YP_002988622.1 KEGG: eca:ECA0976 adenine DNA glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop YP_002988623.1 PFAM: Fe(II) trafficking protein YggX; KEGG: cko:CKO_04337 hypothetical protein YP_002988624.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002988625.1 KEGG: yen:YE0199 hypothetical protein YP_002988626.1 PFAM: protein of unknown function UPF0261; KEGG: eca:ECA0970 hypothetical protein YP_002988627.1 PFAM: regulatory protein TetR; KEGG: eca:ECA0969 TetR family transcriptional regulator YP_002988628.1 PFAM: amino acid permease-associated region; KEGG: ypy:YPK_2256 amino acid permease-associated region YP_002988629.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: eca:ECA0967 ornithine decarboxylase YP_002988630.1 PFAM: integrase family protein; KEGG: stt:t4371 bacteriophage integrase YP_002988631.1 KEGG: ecc:c1442 hypothetical protein YP_002988632.1 KEGG: yen:YE1926 hypothetical protein YP_002988633.1 KEGG: ypm:YP_pCRY21 hypothetical protein YP_002988634.1 KEGG: eum:ECUMN_2300 MobC mobilization protein YP_002988635.1 PFAM: Post-segregation antitoxin CcdA; KEGG: eca:ECA0511 plasmid maintenance protein CcdA YP_002988636.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_002988637.1 KEGG: asa:ASA_P4G176 hypothetical protein YP_002988638.1 SMART: DEAD-like helicase; KEGG: asa:ASA_P4G175 hypothetical protein YP_002988639.1 KEGG: asa:ASA_P4G174 hypothetical protein YP_002988640.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: ecf:ECH74115_0302 DNA-invertase YP_002988641.1 PFAM: type III restriction protein res subunit; KEGG: cja:CJA_1582 type III restriction system endonuclease YP_002988642.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: bpt:Bpet4236 type III restriction system methylase YP_002988643.1 PFAM: integrase family protein; KEGG: eca:ECA0546 shufflon-specific DNA recombinase YP_002988644.1 KEGG: eca:ECA0958 hypothetical protein YP_002988645.1 PFAM: protein of unknown function DUF1528; KEGG: spq:SPAB_05448 hypothetical protein YP_002988646.1 KEGG: yen:YE3457 hypothetical protein YP_002988647.1 KEGG: spq:SPAB_05446 hypothetical protein YP_002988648.1 PFAM: carbamoyltransferase; KEGG: mlo:mlr6171 nodulation protein NolO YP_002988649.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_002988650.1 KEGG: spe:Spro_3428 MbtH domain-containing protein YP_002988651.1 PFAM: MbtH domain protein; KEGG: pae:PA2412 hypothetical protein YP_002988652.1 PFAM: peptidase S45 penicillin amidase; KEGG: rme:Rmet_1578 peptidase S45, penicillin amidase YP_002988653.1 KEGG: nmu:Nmul_A1823 cyclic peptide transporter; TIGRFAM: cyclic peptide transporter; PFAM: ABC transporter; SMART: ATPase AAA YP_002988654.1 PFAM: beta-lactamase; KEGG: gsu:GSU1378 beta-lactamase YP_002988655.1 KEGG: rso:RS03728 hypothetical protein YP_002988656.1 TIGRFAM: amino acid adenylation protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: bbt:BBta_6812 arthrofactin synthetase/syringopeptin synthetase C-related non-ribosomal peptide synthetase module YP_002988657.1 PFAM: aminotransferase class I and II; KEGG: plu:plu1105 hypothetical protein YP_002988658.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: plu:plu1104 hypothetical protein YP_002988659.1 TIGRFAM: amino acid adenylation protein; non-ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; methyltransferase type 11; MCP methyltransferase CheR-type; Luciferase-like monooxygenase; methyltransferase type 12; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3779 non-ribosomal peptide synthetase/polyketide synthase YP_002988660.1 PFAM: Luciferase-like monooxygenase; KEGG: bam:Bamb_6477 short-chain dehydrogenase/reductase SDR YP_002988661.1 PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: pen:PSEEN1815 peptide synthase YP_002988662.1 KEGG: bja:bll2235 hypothetical protein YP_002988663.1 PFAM: beta-ketoacyl synthase ; KR domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: bte:BTH_I2363 polyketide synthase YP_002988664.1 TIGRFAM: amino acid adenylation protein; methyltransferase FkbM family; PFAM: AMP-dependent synthetase and ligase; methyltransferase type 11; methyltransferase type 12; phosphopantetheine-binding; condensation domain protein; KEGG: nmu:Nmul_A1829 amino acid adenylation YP_002988665.1 PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: scl:sce8262 non-ribosomal peptide synthetase YP_002988666.1 KEGG: hch:HCH_04105 ATPase YP_002988667.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_002988668.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: esa:ESA_00798 hypothetical protein YP_002988669.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_002988670.1 KEGG: yen:YE3464 hypothetical protein YP_002988671.1 PFAM: transposase mutator type; KEGG: yen:YEP0069 transposase YP_002988672.1 PFAM: transposase IS3/IS911 family protein; KEGG: yen:YE1123 IS1400 transposase A YP_002988673.1 PFAM: protein of unknown function DUF1778; KEGG: eca:ECA0958 hypothetical protein YP_002988674.1 PFAM: peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; KEGG: mlo:mll9373 acyl-CoA-6-aminopenicillanic acid acyltransferase YP_002988675.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bam:Bamb_4244 GCN5-related N-acetyltransferase YP_002988677.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sdn:Sden_3736 AMP-dependent synthetase and ligase YP_002988678.1 TIGRFAM: amino acid adenylation protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; Non-ribosomal peptide synthetase; condensation domain protein; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase YP_002988679.1 PFAM: tRNA synthetase class I (M); Cupin 2 conserved barrel domain protein; KEGG: mlo:mlr5926 tRNA synthetase YP_002988680.1 PFAM: FAD dependent oxidoreductase; KEGG: bpy:Bphyt_0282 FAD dependent oxidoreductase YP_002988681.1 KEGG: mlo:mlr5923 lysine:N6-hydroxylase YP_002988682.1 PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_4401 major facilitator transporter YP_002988683.1 KEGG: plu:plu0116 hypothetical protein YP_002988684.1 KEGG: bcj:BCAM2153 cytochrome P450 oxidoreductase YP_002988685.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: aav:Aave_3176 acyl-CoA dehydrogenase domain-containing protein YP_002988686.1 KEGG: bpy:Bphyt_0257 hypothetical protein YP_002988687.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: ppu:PP_3787 hypothetical protein YP_002988688.1 KEGG: bch:Bcen2424_4919 PEP phosphonomutase YP_002988689.1 PFAM: thioesterase; KEGG: pen:PSEEN2139 thioesterase YP_002988690.1 PFAM: acyl-CoA dehydrogenase type 2 domain; acyl-CoA dehydrogenase domain protein; KEGG: ses:SARI_00502 hypothetical protein YP_002988691.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA1084 hypothetical protein YP_002988692.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1085 LysR family transcriptional regulator YP_002988693.1 PFAM: Post-segregation antitoxin CcdA; KEGG: eca:ECA0511 plasmid maintenance protein CcdA YP_002988694.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_002988695.1 PFAM: alanine racemase domain protein; KEGG: pol:Bpro_0661 D-serine deaminase YP_002988696.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bph:Bphy_6680 ABC transporter YP_002988697.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: bph:Bphy_6679 polar amino acid ABC transporter inner membrane subunit YP_002988698.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: bph:Bphy_6678 polar amino acid ABC transporter inner membrane subunit YP_002988699.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bph:Bphy_6677 extracellular solute-binding protein YP_002988700.1 PFAM: endoribonuclease L-PSP; KEGG: csa:Csal_0090 endoribonuclease L-PSP YP_002988701.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: bph:Bphy_6681 IclR family transcriptional regulator YP_002988702.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: dal:Dalk_3686 methyltransferase type 11 YP_002988703.1 KEGG: aha:AHA_1727 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase YP_002988704.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA1084 hypothetical protein YP_002988705.1 TIGRFAM: arsenic resistance protein; PFAM: Bile acid:sodium symporter; KEGG: see:SNSL254_A2186 arsenic resistance protein YP_002988706.1 PFAM: regulatory protein ArsR; transcriptional regulator TrmB; SMART: regulatory protein ArsR; KEGG: sea:SeAg_B2124 arsenic resistance transcriptional regulator YP_002988707.1 KEGG: aha:AHA_3686 histidine kinase-response regulator hybrid protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; PAS domain containing protein YP_002988709.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_002988710.1 KEGG: ppd:Ppro_1341 response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver YP_002988711.1 KEGG: psb:Psyr_2940 PAS; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; CHASE domain protein; PAS fold-3 domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; response regulator receiver; PAS domain containing protein YP_002988712.1 PFAM: ApbE family lipoprotein; KEGG: ent:Ent638_2557 ApbE family lipoprotein YP_002988713.1 TIGRFAM: flavocytochrome C; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein; NADH:flavin oxidoreductase/NADH oxidase; KEGG: ent:Ent638_2558 flavocytochrome C YP_002988714.1 KEGG: eta:ETA_30660 methyl-accepting chemotaxis sensory transducer; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer YP_002988715.1 PFAM: helix-turn-helix HxlR type; KEGG: ccs:CCNA_03479 MarR family transcriptional regulator YP_002988716.1 PFAM: acriflavin resistance protein; type II secretion system protein I/J; KEGG: kpe:KPK_2668 RND transporter hydrophobe/amphiphile efflux-1 (HAE1) family YP_002988717.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: bbt:BBta_0809 hypothetical protein YP_002988718.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: esa:ESA_pESA3p05442 hypothetical protein YP_002988719.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: kpe:KPK_2665 DNA-binding response regulator YP_002988720.1 PFAM: MltA-interacting MipA family protein; KEGG: esa:ESA_pESA3p05440 hypothetical protein YP_002988721.1 PFAM: HpcH/HpaI aldolase; KEGG: pap:PSPA7_3089 4-hydroxy-2-oxovalerate aldolase YP_002988722.1 KEGG: xcv:XCV3307 siderophore biosynthesis protein YP_002988723.1 PFAM: IucA/IucC family protein; KEGG: pap:PSPA7_3092 IucA/IucC YP_002988724.1 PFAM: major facilitator superfamily MFS_1; KEGG: xac:XAC3179 transporter YP_002988725.1 PFAM: IucA/IucC family protein; KEGG: swp:swp_0088 AcsD YP_002988726.1 PFAM: Orn/DAP/Arg decarboxylase 2; alanine racemase domain protein; KEGG: xca:xccb100_1140 diaminopimelate decarboxylase YP_002988727.1 PFAM: periplasmic binding protein; KEGG: yen:YE0555 iron transporter YP_002988728.1 TIGRFAM: TonB-dependent siderophore receptor; outer membrane insertion C-terminal signal; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pap:PSPA7_3090 ferric vibrioferrin receptor YP_002988729.1 PFAM: iron permease FTR1; KEGG: spe:Spro_2929 iron permease FTR1 YP_002988730.1 KEGG: spe:Spro_2928 hypothetical protein YP_002988731.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: spe:Spro_2927 Dyp-type peroxidase family protein YP_002988732.1 KEGG: eca:ECA1998 hypothetical protein YP_002988733.1 KEGG: aha:AHA_3054 hypothetical protein YP_002988734.1 PFAM: protein of unknown function DUF81; KEGG: mms:mma_1887 hypothetical protein YP_002988735.1 PFAM: NUDIX hydrolase; KEGG: bha:BH1893 hypothetical protein YP_002988736.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bbr:BB1011 LysR family transcriptional regulator YP_002988737.1 PFAM: PRD domain protein; Helix-turn-helix type 11 domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: eta:ETA_29240 phosphotransferase system mannitol/fructose-specific IIA domain YP_002988738.1 PFAM: protein of unknown function DUF1341; KEGG: ent:Ent638_0431 hypothetical protein YP_002988739.1 TIGRFAM: pyridoxal phosphate-dependent enzyme; PFAM: L-seryl-tRNA selenium transferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: eta:ETA_29260 selenocysteine synthase YP_002988740.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002988741.1 KEGG: kpn:KPN_04637 inner membrane protein YP_002988742.1 KEGG: spe:Spro_4378 hypothetical protein YP_002988743.1 KEGG: yen:YE3784 hypothetical protein YP_002988744.1 KEGG: eta:ETA_29320 hypothetical protein YP_002988745.1 PFAM: PRD domain protein; KEGG: stm:STM4440 cytoplasmic protein YP_002988746.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA1009 biotin sulfoxide reductase YP_002988747.1 PFAM: conserved hypothetical protein; KEGG: ecc:c3738 hypothetical protein YP_002988748.1 SMART: helix-turn-helix domain protein; KEGG: plu:plu1490 hypothetical protein YP_002988749.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: spe:Spro_4196 hypothetical protein YP_002988750.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002988751.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: reu:Reut_B5653 LysR family transcriptional regulator YP_002988752.1 KEGG: reh:H16_A0477 3-isopropylmalate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_002988753.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA0930 permease YP_002988754.1 PFAM: extracellular solute-binding protein family 1; KEGG: hch:HCH_03296 ABC-type sugar transporter, periplasmic component YP_002988755.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hch:HCH_03297 ABC-type sugar transporter, permeases YP_002988756.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hch:HCH_03298 ABC-type sugar transporter, permease YP_002988757.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: mfa:Mfla_2347 ABC transporter YP_002988758.1 KEGG: hch:HCH_04196 beta-lactamase superfamily hydrolase YP_002988759.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: hch:HCH_03302 transcriptional regulator YP_002988760.1 TIGRFAM: selenium-binding protein YdfZ; KEGG: ent:Ent638_1936 cytoplasmic protein YP_002988761.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0916 LysR family transcriptional regulator YP_002988762.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: eca:ECA0915 hypothetical protein YP_002988763.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA0914 component of polysulfide reductase YP_002988764.1 TIGRFAM: cytochrome C nitrite reductase, NrfD subunit; PFAM: polysulphide reductase NrfD; KEGG: eca:ECA0913 component of polysulfide reductase YP_002988765.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0912 hypothetical protein YP_002988766.1 PFAM: FMN-binding domain protein; KEGG: eca:ECA0911 hypothetical protein YP_002988767.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: eca:ECA0910 flavoprotein subunit of a reductase YP_002988768.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: eca:ECA0909 alkylated DNA repair protein YP_002988769.1 KEGG: eca:ECA0907 DNA-3-methyladenine glycosylase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein YP_002988770.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, subunit alpha; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: eca:ECA0904 fumarate hydratase class I, aerobic YP_002988771.1 DHBP synthase; functions during riboflavin biosynthesis YP_002988772.1 PFAM: protein of unknown function DUF526; KEGG: spe:Spro_4287 hypothetical protein YP_002988773.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_002988774.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002988775.1 PFAM: protein of unknown function DUF540; KEGG: eca:ECA0895 sulfate transporter CysZ YP_002988776.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_002988777.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: ypg:YpAngola_A2748 phosphohistidinoprotein-hexose phosphotransferase component of PTS system (HPr) YP_002988778.1 phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transporter YP_002988779.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002988780.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: spe:Spro_3451 integral membrane sensor signal transduction histidine kinase YP_002988781.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: eca:ECA0889 two-component system response regulator YP_002988783.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: eca:ECA0888 macrolide-specific efflux protein maca precursor YP_002988784.1 PFAM: ABC transporter; protein of unknown function DUF214; SMART: ATPase AAA; KEGG: eca:ECA0887 macrolide-specific ABC-type efflux carrier YP_002988785.1 TIGRFAM: cysteine synthase B; cysteine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: plu:plu1391 cysteine synthase B YP_002988786.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: eca:ECA0882 hypothetical protein YP_002988787.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: eca:ECA0932 permease YP_002988788.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: eca:ECA0933 LuxR family transcriptional regulator YP_002988789.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE0513 acetyltransferase YP_002988790.1 KEGG: eca:ECA0686 sugar fermentation stimulation protein YP_002988791.1 PFAM: protein of unknown function DUF1131; KEGG: ypg:YpAngola_A2779 hypothetical protein YP_002988793.1 PFAM: aminotransferase class V; KEGG: pca:Pcar_1860 cysteine sulfinate desulfinase/cysteine desulfurase YP_002988794.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: gsu:GSU3407 hypothetical protein YP_002988795.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0875 acetyltransferase YP_002988796.1 PFAM: coproporphyrinogen III oxidase; KEGG: eca:ECA0874 coproporphyrinogen III oxidase YP_002988797.1 PFAM: protein of unknown function DUF188; KEGG: spe:Spro_3465 hypothetical protein YP_002988798.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002988799.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA0847 MutT/NUDIX family protein YP_002988800.1 TIGRFAM: Mn2+/Fe2+ transporter NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: eca:ECA0843 manganese transporter MntH YP_002988801.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002988802.1 PFAM: ATP-NAD/AcoX kinase; KEGG: eca:ECA0841 inorganic polyphosphate/ATP-NAD kinase YP_002988803.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: eca:ECA0840 recombination and repair protein YP_002988804.1 PFAM: SmpA/OmlA domain protein; KEGG: eca:ECA0839 hypothetical protein YP_002988805.1 PFAM: protein of unknown function UPF0125; KEGG: eca:ECA0838 hypothetical protein YP_002988806.1 PFAM: cyclase/dehydrase; KEGG: eca:ECA0837 hypothetical protein YP_002988807.1 TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; KEGG: cko:CKO_03942 hypothetical protein YP_002988808.1 CP4-57 prophage; integrase YP_002988809.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ses:SARI_03129 hypothetical protein YP_002988810.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ses:SARI_03129 hypothetical protein YP_002988811.1 KEGG: spq:SPAB_01127 hypothetical protein YP_002988812.1 KEGG: smd:Smed_5452 hypothetical protein YP_002988814.1 KEGG: dar:Daro_3104 hypothetical protein YP_002988815.1 KEGG: spe:Spro_0117 hypothetical protein YP_002988816.1 PFAM: extracellular solute-binding protein family 1; KEGG: ses:SARI_00892 hypothetical protein YP_002988817.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ses:SARI_00893 hypothetical protein YP_002988818.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: ses:SARI_00894 hypothetical protein YP_002988819.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA2065 N-acylamino acid racemase YP_002988820.1 PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_0231 major facilitator transporter YP_002988821.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mmw:Mmwyl1_3825 LysR family transcriptional regulator YP_002988822.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_002988823.1 KEGG: mmw:Mmwyl1_0140 methyl-accepting chemotaxis sensory transducer; TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; chemotaxis sensory transducer; hypothetical protein; SMART: chemotaxis sensory transducer; PAC repeat-containing protein; PAS domain containing protein YP_002988824.1 PFAM: amino acid permease-associated region; KEGG: eta:ETA_33160 amino acid permease-associated protein YP_002988825.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: dvm:DvMF_1315 iron-containing alcohol dehydrogenase YP_002988826.1 PFAM: aminotransferase class-III; KEGG: 4-aminobutyrate transaminase YP_002988827.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mmw:Mmwyl1_0462 helix-turn-helix domain-containing protein YP_002988828.1 KEGG: yen:YE3211 D-alanine--D-alanine ligase A; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp YP_002988829.1 PFAM: YCII-related; KEGG: yen:YE1740 hypothetical protein YP_002988830.1 PFAM: DinI family protein; KEGG: yen:YE1408 stress response protein YP_002988831.1 KEGG: sed:SeD_A1838 lipoprotein YnfC YP_002988832.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB1066 acetyltransferase YP_002988833.1 KEGG: eca:ECA0825 hypothetical protein YP_002988834.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA0824 pyruvate-flavodoxin oxidoreductase YP_002988835.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA0821 hypothetical protein YP_002988836.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bpt:Bpet2973 MarR family transcriptional regulator YP_002988837.1 PFAM: secretion protein HlyD; KEGG: maq:Maqu_0618 secretion protein HlyD YP_002988838.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: maq:Maqu_0617 EmrB/QacA family drug resistance transporter YP_002988839.1 SMART: helix-turn-helix domain protein; KEGG: xau:Xaut_0314 XRE family transcriptional regulator YP_002988840.1 KEGG: eca:ECA0817 oligogalacturonide transporter YP_002988841.1 KEGG: eca:ECA0815 hypothetical protein YP_002988842.1 KEGG: eca:ECA0809 global regulatory protein YP_002988844.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002988845.1 PFAM: protein of unknown function DUF485; KEGG: eca:ECA0807 hypothetical protein YP_002988846.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_002988847.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: eca:ECA0784 sodium/hydrogen antiporter YP_002988848.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: eca:ECA0783 permease YP_002988849.1 PFAM: TOBE domain protein; KEGG: eum:ECUMN_3055 molybdenum-pterin-binding-protein YP_002988850.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpn:KPN_04682 sn-glycerol-3-phosphate transporter permease YP_002988851.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpn:KPN_04681 sn-glycerol-3-phosphate transporter permease YP_002988852.1 PFAM: metallophosphoesterase; KEGG: kpn:KPN_04680 phosphohydrolase YP_002988853.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: kpe:KPK_4986 sugar ABC transporter ATP-binding protein YP_002988854.1 PFAM: extracellular solute-binding protein family 1; KEGG: kpe:KPK_4987 ABC transporter periplasmic substrate-binding protein YP_002988855.1 PFAM: sugar transferase; KEGG: vco:VC0395_A2640 capsule biosynthesis protein YP_002988856.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: vco:VC0395_A2639 UDP-glucose 4-epimerase YP_002988857.1 PFAM: polysaccharide biosynthesis protein CapD; Male sterility domain; dTDP-4-dehydrorhamnose reductase; NAD-dependent epimerase/dehydratase; KEGG: vch:VC0260 mannosyl-transferase YP_002988858.1 PFAM: glycosyl transferase group 1; KEGG: aha:AHA_2894 glycosyl transferase, group 1 YP_002988859.1 PFAM: glycosyl transferase group 1; KEGG: ppw:PputW619_1410 glycosyl transferase group 1 YP_002988860.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: ppw:PputW619_1409 NAD-dependent epimerase/dehydratase YP_002988861.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: bam:Bamb_0759 GDP-mannose 4,6-dehydratase YP_002988862.1 PFAM: glycosyl transferase group 1; KEGG: psp:PSPPH_0957 mannosyltransferase YP_002988863.1 KEGG: bam:Bamb_0757 methyltransferase type 11 YP_002988864.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; KEGG: aha:AHA_2903 phosphomannomutase YP_002988865.1 KEGG: pol:Bpro_4942 mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; nucleotidyl transferase; Cupin 2 conserved barrel domain protein YP_002988866.1 PFAM: helix-turn-helix HxlR type; KEGG: xau:Xaut_0313 HxlR family transcriptional regulator YP_002988867.1 PFAM: methionine synthase vitamin-B12 independent; KEGG: cko:CKO_01563 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YP_002988869.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: apa:APP7_1471 dTDP-glucose 4,6-dehydratase YP_002988870.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; KEGG: shl:Shal_1487 glucose-1-phosphate thymidylyltransferase YP_002988871.1 TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; NAD-dependent epimerase/dehydratase; KEGG: vsa:VSAL_I3020 dTDP-6-deoxy-L-mannose-dehydrogenase YP_002988872.1 KEGG: vsa:VSAL_I3021 dTDP-6-deoxy-D-xylo-4-hexulose-3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_002988873.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA0776 hypothetical protein YP_002988874.1 PFAM: protein of unknown function DUF979; KEGG: eta:ETA_23120 predicted membrane protein YP_002988875.1 PFAM: protein of unknown function DUF969; KEGG: spe:Spro_1258 hypothetical protein YP_002988876.1 PFAM: carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: plu:plu4306 hypothetical protein YP_002988877.1 KEGG: aav:Aave_3511 allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 2; allophanate hydrolase subunit 1 YP_002988878.1 PFAM: LamB/YcsF family protein; KEGG: pst:PSPTO_5378 hypothetical protein YP_002988879.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: plu:plu4300 hypothetical protein YP_002988880.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002988881.1 KEGG: bpm:BURPS1710b_1732 hypothetical protein YP_002988882.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: eca:ECA0772 ssDNA exonuclease RecJ YP_002988883.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_002988884.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase; KEGG: eca:ECA0770 site-specific tyrosine recombinase XerD YP_002988885.1 PFAM: HpcH/HpaI aldolase; KEGG: kpn:KPN_02650 aldolase YP_002988886.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA0769 transporter YP_002988887.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_002988888.1 PFAM: protein of unknown function DUF1434; KEGG: eca:ECA0760 hypothetical protein YP_002988889.1 PFAM: protein of unknown function DUF339; KEGG: eca:ECA0759 hypothetical protein YP_002988890.1 TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: eca:ECA0758 global regulator YP_002988891.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: eca:ECA0757 hypothetical protein YP_002988892.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: spe:Spro_3901 metal dependent phosphohydrolase YP_002988893.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002988894.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002988895.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002988896.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bam:Bamb_3990 extracellular solute-binding protein YP_002988897.1 KEGG: bam:Bamb_3989 polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: ABC transporter; binding-protein-dependent transporters inner membrane component; SMART: ATPase AAA YP_002988898.1 PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; KEGG: bac:BamMC406_4450 GntR family transcriptional regulator YP_002988899.1 KEGG: bmj:BMULJ_04417 hypothetical protein YP_002988900.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA0742 L-1,2-propanediol oxidoreductase YP_002988901.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_002988902.1 KEGG: yen:YE4016 alpha-acetolactate decarboxylase; TIGRFAM: alpha-acetolactate decarboxylase; PFAM: alpha-acetolactate decarboxylase YP_002988903.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0739 LysR family transcriptional regulator YP_002988904.1 KEGG: spe:Spro_0646 hypothetical protein YP_002988905.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0737 LysR family transcriptional regulator YP_002988906.1 PFAM: aldo/keto reductase; KEGG: eca:ECA0736 aldo/keto reductase YP_002988907.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_002988908.1 PFAM: DNA polymerase III psi subunit; KEGG: spe:Spro_0650 DNA polymerase III subunit psi YP_002988909.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_002988910.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: azo:azo2513 RNA polymerase ECF-subfamily sigma factor YP_002988911.1 PFAM: FecR protein; KEGG: neu:NE1218 FecR protein YP_002988912.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Secretin/TonB short domain; KEGG: ccv:CCV52592_0400 ferripyoverdine receptor YP_002988913.1 PFAM: ABC transporter domain protein; ABC transporter related; SbmABacA family protein; SMART: ATPase AAA; KEGG: swp:swp_4955 ABC-type uncharacterized transporter, permease and ATPase components YP_002988914.1 TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: eta:ETA_06690 purine nucleoside phosphorylase DeoD-type YP_002988915.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002988916.1 KEGG: eca:ECA0728 thymidine phosphorylase; TIGRFAM: thymidine phosphorylase; pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; glycosyl transferase, family 3-like YP_002988917.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002988918.1 PFAM: excinuclease ABC C subunit domain protein; KEGG: yen:YE0453 GIY-YIG nuclease superfamily protein YP_002988919.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0724 acetyltransferase YP_002988920.1 PFAM: sterol-binding domain protein; KEGG: eca:ECA0723 sterol transferase YP_002988921.1 PFAM: peptidase U32; KEGG: eca:ECA0722 protease YP_002988922.1 PFAM: peptidase U32; KEGG: yen:YE0449 hypothetical protein YP_002988923.1 PFAM: Luciferase-like monooxygenase; KEGG: yen:YE0442 hypothetical protein YP_002988924.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_002988925.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002988926.1 KEGG: eca:ECA0716 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; RNA binding S1 domain protein; Exoribonuclease, phosphorolytic domain 2; KH type 1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein YP_002988927.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002988928.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; tRNA pseudouridine synthase B; KEGG: eca:ECA0714 tRNA pseudouridine synthase B YP_002988929.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002988930.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002988931.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002988932.1 PFAM: protein of unknown function DUF150; KEGG: eta:ETA_03450 YhbC-like protein YP_002988933.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: eta:ETA_03440 protein-export membrane protein SecG (preprotein translocase band 1 subunit) YP_002988934.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002988935.1 KEGG: yps:YPTB0475 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS YP_002988936.1 KEGG: kpe:KPK_0533 ATP-dependent metallopeptidase HflB; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; peptidase M41 FtsH extracellular; ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA YP_002988937.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002988938.1 PFAM: protein of unknown function UPF0044; KEGG: eca:ECA0696 hypothetical protein YP_002988939.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: eca:ECA0695 transcription elongation factor GreA YP_002988940.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002988941.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002988942.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA0692 hypothetical protein YP_002988943.1 TIGRFAM: ribosomal protein L27; PFAM: ribosomal protein L27; KEGG: kpn:KPN_03595 50S ribosomal protein L27 YP_002988944.1 TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: eca:ECA0690 50S ribosomal protein L21 YP_002988945.1 PFAM: polyprenyl synthetase; KEGG: eca:ECA0689 octaprenyl diphosphate synthase YP_002988946.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: eca:ECA0688 hypothetical protein YP_002988947.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: eca:ECA0687 DNA-binding protein YP_002988948.1 KEGG: eca:ECA0686 sugar fermentation stimulation protein YP_002988949.1 oxidizes malate to oxaloacetate YP_002988950.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002988951.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002988952.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002988953.1 synthesizes RNA primers at the replication forks YP_002988954.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002988955.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_002988956.1 KEGG: kpn:KPN_00568 ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002988957.1 KEGG: kpe:KPK_4018 oligopeptide/dipeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002988958.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpe:KPK_4019 oligopeptide/dipeptide ABC transporter permease YP_002988959.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: kpe:KPK_4020 oligopeptide/dipeptide ABC transporter permease YP_002988960.1 PFAM: extracellular solute-binding protein family 5; KEGG: kpe:KPK_4021 oligopeptide/dipeptide ABC transporter periplasmic oligopeptide/dipeptide-binding protein YP_002988961.1 PFAM: protein of unknown function Spy-related; KEGG: kpn:KPN_01226 periplasmic protein YP_002988962.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: eca:ECA1499 pectin lyase YP_002988963.1 KEGG: eca:ECA0656 hypothetical protein YP_002988964.1 PFAM: methyltransferase small; KEGG: eca:ECA0654 hypothetical protein YP_002988965.1 PFAM: integral membrane protein TerC; KEGG: eca:ECA0652 hypothetical protein YP_002988966.1 KEGG: eca:ECA0648 hypothetical protein YP_002988967.1 PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; SAF domain protein; KEGG: eca:ECA0647 altronate hydrolase YP_002988968.1 catalyzes the formation of D-tagaturonate from D-altronate YP_002988969.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_002988970.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0644 galacturonate transporter YP_002988971.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_002988972.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA0642 DedA family membrane protein YP_002988973.1 KEGG: eca:ECA0641 hypothetical protein YP_002988974.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: eca:ECA0639 hypothetical protein YP_002988975.1 KEGG: eca:ECA0638 hypothetical protein YP_002988976.1 KEGG: yen:YE3717 hypothetical protein YP_002988977.1 PFAM: DoxX family protein; KEGG: eca:ECA0636 hypothetical protein YP_002988978.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA0635 hypothetical protein YP_002988979.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: esa:ESA_03530 hypothetical protein YP_002988980.1 PFAM: pirin; KEGG: eca:ECA0633 hypothetical protein YP_002988981.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_002988982.1 Represses a number of genes involved in the response to DNA damage YP_002988983.1 PFAM: diacylglycerol kinase; KEGG: eca:ECA0629 diacylglycerol kinase YP_002988984.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002988985.1 catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_002988986.1 PFAM: chorismate lyase; KEGG: eca:ECA0626 chorismate pyruvate lyase YP_002988987.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: kpe:KPK_5137 chaperonin GroL YP_002988988.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002988989.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: eca:ECA0623 suppressor of F plamsid exlusion of phage T7 YP_002988991.1 catalyzes the formation of fumarate from aspartate YP_002988992.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002988993.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_002988994.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002988995.1 PFAM: regulatory protein TetR; KEGG: yps:YPTB0395 transcriptional regulator YP_002988996.1 PFAM: integrase family protein; KEGG: stt:t4371 bacteriophage integrase YP_002988997.1 KEGG: ecq:ECED1_1795 conserved hypothetical protein; repressor (interpro) YP_002988998.1 KEGG: plu:plu1097 hypothetical protein YP_002988999.1 KEGG: eum:ECUMN_2300 MobC mobilization protein YP_002989000.1 PFAM: Post-segregation antitoxin CcdA; KEGG: eca:ECA0511 plasmid maintenance protein CcdA YP_002989001.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_002989002.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); KEGG: sil:SPO1047 RNA-dependent DNA polymerase YP_002989003.1 KEGG: sil:SPO1046 hypothetical protein YP_002989004.1 KEGG: sil:SPO1045 hypothetical protein YP_002989005.1 KEGG: plu:plu0625 hypothetical protein YP_002989006.1 KEGG: yen:YE0485 hypothetical protein YP_002989008.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ses:SARI_03129 hypothetical protein YP_002989010.1 KEGG: sdn:Sden_3310 hypothetical protein YP_002989011.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: eca:ECA0515 hypothetical protein YP_002989012.1 PFAM: GCN5-related N-acetyltransferase; KEGG: stt:t4359 hypothetical protein YP_002989013.1 PFAM: protein of unknown function DUF1778; KEGG: eca:ECA0958 hypothetical protein YP_002989014.1 KEGG: plu:plu1482 hypothetical protein YP_002989015.1 PFAM: RES domain protein; KEGG: plu:plu1483 hypothetical protein YP_002989016.1 PFAM: protein of unknown function DUF134; KEGG: ppr:PBPRB1405 DNA-binding protein YP_002989017.1 KEGG: sfr:Sfri_1975 hypothetical protein YP_002989018.1 PFAM: methyltransferase type 12; Tellurite resistance methyltransferase, TehB, core; methyltransferase type 11; KEGG: mxa:MXAN_4322 thiopurine S-methyltransferase YP_002989019.1 PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: hypothetical protein YP_002989020.1 PFAM: NLPA lipoprotein; KEGG: eca:ECA2066 lipoprotein YP_002989021.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: bph:Bphy_4090 ECF subfamily RNA polymerase sigma-24 factor YP_002989022.1 KEGG: bac:BamMC406_4380 hypothetical protein YP_002989023.1 KEGG: bpy:Bphyt_5023 membrane-associated protein YP_002989024.1 PFAM: hypothetical protein; KEGG: bph:Bphy_4087 hypothetical protein YP_002989025.1 PFAM: protein of unknown function DUF1501; KEGG: bph:Bphy_4086 hypothetical protein YP_002989026.1 KEGG: dar:Daro_2256 MerR family transcriptional regulator; TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR YP_002989027.1 TIGRFAM: ATPase P; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: bxe:Bxe_A4439 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_002989028.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: spe:Spro_3902 major facilitator transporter YP_002989029.1 KEGG: spe:Spro_3903 hypothetical protein YP_002989030.1 PFAM: amidase; KEGG: spe:Spro_3904 amidase YP_002989031.1 KEGG: spe:Spro_3905 hypothetical protein YP_002989032.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: spe:Spro_3906 GntR family transcriptional regulator YP_002989033.1 TIGRFAM: phosphonate metabolim protein, transferase hexapeptide repeat family; KEGG: bja:blr7948 acetyltransferase YP_002989034.1 PFAM: Domain of unknown function DUF1868; KEGG: met:M446_0509 hypothetical protein YP_002989035.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA3941 alkyl hydroperoxide reductase subunit F YP_002989036.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_002989037.1 KEGG: spe:Spro_3158 hypothetical protein YP_002989038.1 KEGG: kpe:KPK_2239 amidohydrolase family protein; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_002989039.1 SMART: metal-dependent phosphohydrolase HD region; KEGG: spe:Spro_0128 metal dependent phosphohydrolase YP_002989040.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA1683 methyl-accepting chemotaxis protein YP_002989041.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: atc:AGR_C_1580 hypothetical protein YP_002989042.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: eca:ECA0474 enterobactin synthetase component D (4'-phosphopantetheinyl transferase) YP_002989044.1 PFAM: TatD-related deoxyribonuclease; KEGG: eca:ECA0472 TatD family deoxyribonuclease YP_002989045.1 KEGG: eca:ECA0471 hypothetical protein YP_002989046.1 PFAM: protein of unknown function DUF1328; KEGG: sgl:SG0393 hypothetical protein YP_002989047.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: eca:ECA0469 periplasmic protein YP_002989048.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: eca:ECA0468 peptide chain release factor 3 YP_002989049.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: kpe:KPK_2732 trans-aconitate 2-methyltransferase YP_002989050.1 KEGG: eca:ECA0466 hypothetical protein YP_002989051.1 catalyzes the formation of serine from O-phosphoserine YP_002989052.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002989053.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_002989054.1 TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: eca:ECA0462 5-formyltetrahydrofolate cyclo-ligase YP_002989055.1 PFAM: protein of unknown function DUF710; KEGG: eca:ECA0461 Z-ring-associated protein YP_002989056.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002989057.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_002989058.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_002989059.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: eca:ECA0457 hypothetical protein YP_002989060.1 PFAM: protein of unknown function DUF1440; KEGG: cje:Cj0014c integral membrane protein YP_002989061.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0448 ABC transporter extracellular solute binding protein YP_002989062.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0447 ABC transporter permease YP_002989063.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0446 ABC transporter permease YP_002989064.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: eca:ECA0445 ABC transporter ATP binding protein YP_002989065.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA0442 L-rhamnose operon transcriptional activator YP_002989066.1 activates the expression of the rhaBAD operon and rhaT gene YP_002989067.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_002989068.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_002989069.1 KEGG: eca:ECA0438 rhamnulose-1-phosphate aldolase; TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein YP_002989070.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: eca:ECA0437 hypothetical protein YP_002989071.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA0436 methyl-accepting chemotaxis protein YP_002989072.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: wsu:WS0977 oligopeptide transport ATP-binding protein AppF YP_002989073.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sil:SPO1213 oligopeptide ABC transporter ATP-binding protein YP_002989074.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: plu:plu0518 hypothetical protein YP_002989075.1 PFAM: major facilitator superfamily MFS_1; KEGG: pmr:PMI3395 MFS-family transporter YP_002989076.1 catalyzes the interconversion of chorismate to prephenate YP_002989077.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: psp:PSPPH_1762 AsnC family transcriptional regulator YP_002989079.1 KEGG: plu:plu3301 hypothetical protein YP_002989080.1 PFAM: SMC domain protein; KEGG: plu:plu3302 hypothetical protein YP_002989081.1 catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate YP_002989082.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2075 LysR family transcriptional regulator YP_002989083.1 PFAM: peptidase M20; KEGG: bur:Bcep18194_A4728 hypothetical protein YP_002989084.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: vei:Veis_4730 ABC transporter related YP_002989085.1 KEGG: vei:Veis_4731 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_002989086.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: vei:Veis_4732 binding-protein-dependent transport systems inner membrane component YP_002989087.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mmw:Mmwyl1_3823 binding-protein-dependent transport systems inner membrane component YP_002989088.1 PFAM: extracellular solute-binding protein family 5; KEGG: vei:Veis_4734 extracellular solute-binding protein YP_002989089.1 PFAM: delta-endotoxin CytB; KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_002989090.1 KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_002989091.1 KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_002989092.1 PFAM: delta-endotoxin CytB; KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_002989093.1 PFAM: MmgE/PrpD family protein; KEGG: pfo:Pfl01_2858 MmgE/PrpD YP_002989094.1 PFAM: polysaccharide deacetylase; KEGG: pfo:Pfl01_2857 polysaccharide deacetylase YP_002989095.1 PFAM: polysaccharide deacetylase; KEGG: pfo:Pfl01_2856 polysaccharide deacetylase YP_002989096.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: pfo:Pfl01_2855 extracellular solute-binding protein YP_002989097.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pfo:Pfl01_2854 ABC transporter-like YP_002989098.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pfo:Pfl01_2853 amino acid ABC transporter permease YP_002989099.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002989100.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pfo:Pfl01_2851 LysR family transcriptional regulator YP_002989101.1 KEGG: eca:ECA0432 hypothetical protein YP_002989102.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpe:KPK_3986 oxidoreductase, short chain dehydrogenase/reductase family YP_002989103.1 PFAM: carbohydrate kinase FGGY; KEGG: kpe:KPK_3981 glycerol kinase YP_002989104.1 PFAM: inner-membrane translocator; KEGG: efe:EFER_2521 transporter permease for a carbohydrate-related molecule YP_002989105.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: kpe:KPK_3984 sugar ABC transporter ATP-binding protein YP_002989106.1 KEGG: efe:EFER_2519 lipoprotein YP_002989107.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: efe:EFER_2518 ABC transporter sugar-binding protein YP_002989108.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: oan:Oant_4068 short-chain dehydrogenase/reductase SDR YP_002989109.1 PFAM: transketolase; transketolase domain protein; KEGG: ypg:YpAngola_A0910 transketolase, C-terminal subunit YP_002989110.1 PFAM: transketolase; KEGG: pst:PSPTO_2401 transketolase, N-terminal subunit YP_002989111.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: aba:acid345_0659 DeoR family transcriptional regulator YP_002989113.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_2121 major facilitator transporter YP_002989114.1 KEGG: gbm:Gbem_0820 hypothetical protein YP_002989115.1 KEGG: gme:Gmet_0233 hypothetical protein YP_002989116.1 PFAM: protein of unknown function DUF1471; KEGG: sew:SeSA_A1290 protein YcfR YP_002989117.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: aci:ACIAD0759 threonine efflux protein (RhtC) YP_002989118.1 PFAM: pirin; KEGG: pzu:PHZ_c1158 pirin-related protein YP_002989119.1 PFAM: protein of unknown function DUF891; KEGG: esa:ESA_03838 hypothetical protein YP_002989120.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu0900 hypothetical protein YP_002989121.1 PFAM: integrase family protein; KEGG: plu:plu4477 hypothetical protein YP_002989122.1 PFAM: protein of unknown function DUF1778; KEGG: ecf:ECH74115_4726 hypothetical protein YP_002989123.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ecf:ECH74115_4727 acetyltransferase, GNAT family YP_002989124.1 KEGG: kpn:KPN_02071 enzyme YP_002989125.1 KEGG: stm:PSLT042 integrase protein YP_002989127.1 KEGG: plu:plu4474 hypothetical protein YP_002989128.1 PFAM: P4 alpha zinc-binding domain protein; TOPRIM domain protein; SMART: P4 alpha zinc-binding domain protein; Toprim sub domain protein; KEGG: plu:plu4471 hypothetical protein YP_002989129.1 KEGG: ypp:YPDSF_2605 prophage protein YP_002989130.1 PFAM: prophage CP4-57 regulator; KEGG: ypg:YpAngola_A1363 AlpA family transcriptional regulator YP_002989131.1 KEGG: ypg:YpAngola_A1364 DNA-binding prophage protein YP_002989132.1 KEGG: mgm:Mmc1_0112 hypothetical protein YP_002989133.1 KEGG: mgm:Mmc1_0113 hypothetical protein YP_002989134.1 PFAM: integrase family protein; KEGG: stt:t4518 integrase YP_002989135.1 PFAM: permease YjgP/YjgQ family protein; KEGG: spe:Spro_0564 permease YjgP/YjgQ family protein YP_002989136.1 PFAM: permease YjgP/YjgQ family protein; KEGG: eca:ECA0405 permease YP_002989137.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002989138.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002989139.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002989140.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0390 methyl-accepting chemotaxis protein YP_002989141.1 PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA0389 hypothetical protein YP_002989142.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pzu:PHZ_c0633 acetyltransferase, GNAT family YP_002989143.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; KEGG: spe:Spro_1454 XRE family transcriptional regulator YP_002989144.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0386 acetyltransferase YP_002989145.1 PFAM: protein of unknown function DUF1260; KEGG: eca:ECA0385 hypothetical protein YP_002989146.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_002989147.1 PFAM: glycoside hydrolase family 1; KEGG: vsp:VS_II0097 6-phospho-beta-glucosidase YP_002989148.1 PFAM: phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: yen:YE1416 PTS-system permease YP_002989149.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA0383 hypothetical protein YP_002989150.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002989151.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002989152.1 TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: sty:STY4798 hypothetical protein YP_002989153.1 KEGG: plu:plu1973 hypothetical protein YP_002989154.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: eca:ECA0379 hypothetical protein YP_002989155.1 PFAM: protein of unknown function DUF403; KEGG: eca:ECA0378 hypothetical protein YP_002989156.1 PFAM: transglutaminase; transglutaminase domain protein; SMART: transglutaminase; KEGG: eca:ECA0377 hypothetical protein YP_002989157.1 PFAM: 20S proteasome A and subunit betas; KEGG: eca:ECA0376 hypothetical protein YP_002989159.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: sgl:SG1135 transporter YP_002989160.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002989161.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; KEGG: sea:SeAg_B4733 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002989162.1 KEGG: eca:ECA0372 hypothetical protein YP_002989163.1 KEGG: glo:Glov_1957 methyltransferase type 11 YP_002989164.1 TIGRFAM: CRISPR-associated protein Cas2; KEGG: sew:SeSA_A3091 crispr-associated protein Cas2 YP_002989165.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: ecl:EcolC_0957 CRISPR-associated Cas1 family protein YP_002989166.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: sek:SSPA2606 hypothetical protein YP_002989167.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: sew:SeSA_A3094 CRISPR-associated protein Cas5 YP_002989168.1 TIGRFAM: CRISPR-associated protein, Cse4 family; KEGG: sew:SeSA_A3095 crispr-associated protein, CSE4 family YP_002989169.1 TIGRFAM: CRISPR-associated protein, Cse2 family; KEGG: sew:SeSA_A3096 crispr-associated protein, CSE2 family YP_002989170.1 TIGRFAM: CRISPR-associated protein, Cse1 family; KEGG: sew:SeSA_A3097 crispr-associated protein, CSE1 family YP_002989171.1 TIGRFAM: CRISPR-associated helicase Cas3; KEGG: ecf:ECH74115_4014 CRISPR-associated helicase Cas3 YP_002989172.1 PFAM: PfkB domain protein; KEGG: eca:ECA0364 aminoimidazole riboside kinase YP_002989173.1 PFAM: porin LamB type; KEGG: eca:ECA0363 sucrose porin YP_002989174.1 TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PTS system, maltose and glucose-specific subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: eca:ECA0362 PTS system, sucrose-specific IIBC component YP_002989175.1 KEGG: eca:ECA0361 sucrose-6-phosphate hydrolase; TIGRFAM: sucrose-6-phosphate hydrolase; PFAM: glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32 YP_002989176.1 KEGG: eca:ECA0360 sucrose operon repressor; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI YP_002989177.1 TIGRFAM: TonB system transporter ExbD; PFAM: biopolymertransporter ExbD/TolR; KEGG: eca:ECA0359 biopolymer transport protein ExbD YP_002989178.1 TIGRFAM: tonB-system energizer ExbB; PFAM: MotA/TolQ/ExbB proton channel; KEGG: eca:ECA0358 biopolymer transporter YP_002989179.1 catalyzes the formation of L-homocysteine from cystathionine YP_002989180.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA0353 DedA family membrane protein YP_002989181.1 PFAM: AraC-type transcriptional regulator; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA0352 AraC family transcription regulator YP_002989182.1 PFAM: nitroreductase; KEGG: eca:ECA0351 nitroreductase YP_002989183.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: spe:Spro_4215 iron-containing alcohol dehydrogenase YP_002989184.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_002989185.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein Crp; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0348 GntR family transcriptional regulator YP_002989186.1 PFAM: ADP-ribosylation/crystallin J1; KEGG: ecz:ECS88_2241 (phospho)hydrolase YP_002989187.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: psb:Psyr_2922 permease for cytosine/purines, uracil, thiamine, allantoin YP_002989188.1 PFAM: PfkB domain protein; KEGG: plu:plu4883 hypothetical protein YP_002989189.1 PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: eca:ECA0347 repressor protein for FtsI YP_002989190.1 KEGG: eca:ECA0346 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase YP_002989191.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002989192.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: eca:ECA0337 modulator of drug activity B YP_002989193.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0336 LysR family transcriptional regulator YP_002989194.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002989195.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002989196.1 PFAM: calcineurin phosphoesterase; metallophosphoesterase; KEGG: eca:ECA0333 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002989197.1 PFAM: protein of unknown function DUF1249; KEGG: spe:Spro_4266 hypothetical protein YP_002989198.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002989199.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002989200.1 PFAM: protein of unknown function DUF1190; KEGG: eca:ECA0329 hypothetical protein YP_002989201.1 PFAM: glutathionylspermidine synthase; KEGG: plu:plu3957 hypothetical protein YP_002989202.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_002989203.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA0323 tetrapyrrole methylase YP_002989204.1 PFAM: LppC family lipoprotein; KEGG: eca:ECA0322 hypothetical protein YP_002989205.1 PFAM: protein of unknown function UPF0102; KEGG: spe:Spro_4337 hypothetical protein YP_002989206.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_002989207.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: eca:ECA0319 hypothetical protein YP_002989208.1 KEGG: eca:ECA0318 hypothetical protein YP_002989209.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002989210.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA0316 isoprenoid biosynthesis protein YP_002989211.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002989212.1 KEGG: eca:ECA0313 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB YP_002989213.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_002989214.1 glutamate synthase is composed of subunits alpha and beta; subunit beta is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the subunit alpha, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_002989215.1 PFAM: stringent starvation protein B; KEGG: efe:EFER_3198 ClpXP protease specificity-enhancing factor YP_002989216.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002989217.1 PFAM: ribosomal protein S9; KEGG: eca:ECA0307 30S ribosomal protein S9 YP_002989218.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002989219.1 PFAM: AFG1-family ATPase; KEGG: eca:ECA0305 ATP/GTP-binding protein YP_002989220.1 PFAM: protein of unknown function DUF1043; KEGG: eca:ECA0304 cytochrome d ubiquinol oxidase subunit III YP_002989221.1 KEGG: eca:ECA0303 exported protease; TIGRFAM: protease Do; PFAM: PDZ/DHR/GLGF domain protein; peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein YP_002989222.1 KEGG: ecq:ECED1_3885 serine endoprotease periplasmic; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein YP_002989223.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002989224.1 PFAM: BolA family protein; KEGG: spe:Spro_4355 BolA family protein YP_002989225.1 KEGG: yen:YE3748 anti-sigma B factor antagonist YP_002989226.1 PFAM: toluene tolerance family protein; KEGG: eca:ECA0298 hypothetical protein YP_002989227.1 PFAM: hypothetical protein; KEGG: eca:ECA0297 hypothetical protein YP_002989228.1 PFAM: protein of unknown function DUF140; KEGG: eca:ECA0296 hypothetical protein YP_002989229.1 ATP-binding subunit of a ABC toluene efflux transporter YP_002989230.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_002989231.1 KEGG: eca:ECA0293 D-arabinose 5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; SMART: CBS domain containing protein YP_002989232.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002989233.1 PFAM: protein of unknown function DUF1239; KEGG: spe:Spro_4364 hypothetical protein YP_002989234.1 TIGRFAM: lipopolysaccharide transport periplasmic protein LptA; PFAM: OstA family protein; KEGG: efe:EFER_3177 lipopolysaccharide transporter A: periplasmic-binding component of ABC superfamily YP_002989235.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA0289 ABC transporter ATP-binding protein YP_002989236.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002989237.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: yen:YE3760 sigma(54) modulation protein YP_002989238.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: eca:ECA0286 sugar-specific enzyme IIA component of PTS YP_002989239.1 PFAM: conserved hypothetical protein; KEGG: esa:ESA_03598 hypothetical protein YP_002989240.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: eca:ECA0284 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_002989241.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_002989242.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002989243.1 PFAM: protein of unknown function DUF615; KEGG: spe:Spro_4387 hypothetical protein YP_002989244.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eta:ETA_30500 lysine exporter protein (LysE/YggA) YP_002989245.1 PFAM: protein of unknown function DUF1543; KEGG: sgl:SG0708 hypothetical protein YP_002989246.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002989247.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002989248.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_002989249.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0276 DNA-binding transcriptional regulator YP_002989250.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_002989251.1 KEGG: eca:ECA0272 hypothetical protein YP_002989252.1 involved in the processing of the 5'end of 16S rRNA YP_002989253.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: ypi:YpsIP31758_0401 Maf-like protein YP_002989254.1 part of cell wall structural complex MreBCD; transmembrane component YP_002989255.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002989256.1 functions in MreBCD complex in some organisms YP_002989257.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002989258.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA0265 zinc-binding oxidoreductase YP_002989259.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002989260.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002989261.1 KEGG: eca:ECA0262 3-dehydroquinate dehydratase; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: dehydroquinase class II YP_002989262.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: eca:ECA0261 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002989263.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; RimK domain protein ATP-grasp; phosphoribosylglycinamide synthetase; carbamoyl-phosphate synthetase large chain domain protein; KEGG: ecr:ECIAI1_3399 acetyl-CoA carboxylase, biotin carboxylase subunit YP_002989264.1 PFAM: protein of unknown function DUF997; KEGG: spe:Spro_4419 hypothetical protein YP_002989265.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002989266.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002989267.1 TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase; KEGG: eca:ECA0256 tRNA-dihydrouridine synthase B YP_002989268.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002989269.1 KEGG: ajs:Ajs_0826 DNA ligase III-like protein YP_002989270.1 KEGG: ajs:Ajs_0827 hypothetical protein YP_002989271.1 KEGG: ajs:Ajs_0828 hypothetical protein YP_002989273.1 KEGG: ent:Ent638_2146 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; MHYT domain protein; SMART: EAL domain protein; GGDEF domain containing protein YP_002989274.1 PFAM: protein of unknown function DUF1471; KEGG: plu:plu4502 hypothetical protein YP_002989275.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl01_2570 LysR family transcriptional regulator YP_002989276.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: bvi:Bcep1808_0666 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_002989277.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA0247 cystine-binding periplasmic protein YP_002989278.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0246 amino-acid transporter permease protein YP_002989279.1 KEGG: cko:CKO_01814 hypothetical protein YP_002989280.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA0245 general L-amino ABC transporter binding protein YP_002989281.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0244 L-amino acid ABC transporter permease YP_002989282.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0243 L-amino acid ABC transporter permease YP_002989283.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA0242 L-amino acid ABC transporter ATP-binding protein YP_002989284.1 involved in de novo purine biosynthesis YP_002989285.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002989286.1 PFAM: protein of unknown function DUF1481; KEGG: eca:ECA0239 lipoprotein YP_002989287.1 histone-like DNA-binding protein YP_002989288.1 PFAM: protein of unknown function DUF416; KEGG: eca:ECA0237 lipoprotein YP_002989289.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_002989290.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002989291.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_002989292.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002989293.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_002989294.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF YP_002989295.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS YP_002989296.1 PFAM: thiazole biosynthesis protein; KEGG: eca:ECA0229 thiazole synthase YP_002989297.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_002989298.1 KEGG: spe:Spro_1499 heavy metal sensor signal transduction histidine kinase; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein YP_002989299.1 KEGG: spe:Spro_1498 two component heavy metal response transcriptional regulator; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver YP_002989300.1 KEGG: spe:Spro_1497 hypothetical protein YP_002989301.1 KEGG: spe:Spro_1496 HupC/HyaC/HydC family protein YP_002989302.1 PFAM: oxidoreductase molybdopterin binding; KEGG: spe:Spro_1495 oxidoreductase molybdopterin binding YP_002989303.1 PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eta:ETA_01690 GntR-family transcriptional regulator YP_002989304.1 PFAM: protein of unknown function DUF1127; KEGG: ecj:JW4304 conserved hypothetical protein YP_002989305.1 KEGG: eca:ECA0227 GntR family transcriptional regulator YP_002989306.1 PFAM: protein of unknown function DUF1176; KEGG: pmy:Pmen_3175 hypothetical protein YP_002989307.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002989308.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002989309.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002989310.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002989311.1 TIGRFAM: ribosomal protein L1; PFAM: ribosomal protein L1; KEGG: kpn:KPN_04361 50S ribosomal protein L1 YP_002989312.1 KEGG: eta:ETA_01510 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: ribosomal protein L11; SMART: ribosomal protein L11 YP_002989313.1 Modulates Rho-dependent transcription termination YP_002989314.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002989315.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002989316.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002989317.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002989318.1 KEGG: eca:ECA0213 UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; FAD linked oxidase domain protein YP_002989319.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_002989320.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: eca:ECA0211 potassium transporter YP_002989321.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: spe:Spro_0264 hypothetical protein YP_002989322.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_002989323.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002989324.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002989325.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: pol:Bpro_4847 protein of unknown function DUF395, YeeE/YedE YP_002989326.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: yen:YE3422A hypothetical protein YP_002989327.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: yen:YE3423 transcription regulator ArsR YP_002989328.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: rhodanese; KEGG: aha:AHA_1691 NADH dehydrogenase YP_002989329.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002989330.1 TIGRFAM: UbiD family decarboxylase; PFAM: carboxylyase-related protein; KEGG: eca:ECA0205 3-octaprenyl-4-hydroxybenzoate decarboxylase YP_002989331.1 KEGG: eca:ECA0204 transcriptional activator RfaH; TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; SMART: NGN domain protein YP_002989332.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002989333.1 magnesium dependent; not involved in the Sec-independent protein export system YP_002989334.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_002989335.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: yen:YE0260 sec-independent protein translocase protein TatB YP_002989336.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: eca:ECA0199 sec-independent protein translocase YP_002989337.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002989338.1 PFAM: sterol-binding domain protein; KEGG: eca:ECA0197 hypothetical protein YP_002989339.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: ypa:YPA_0243 ubiquinone/menaquinone biosynthesis methyltransferase YP_002989340.1 PFAM: protein of unknown function DUF195; KEGG: eca:ECA0195 DNA recombination protein YP_002989341.1 TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Proline dehydrogenase; aldehyde dehydrogenase; KEGG: spe:Spro_2931 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002989342.1 TIGRFAM: sodium/proline symporter; SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: eca:ECA4218 sodium/proline symporter YP_002989344.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002989345.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002989346.1 KEGG: eca:ECA4223 hypothetical protein YP_002989347.1 KEGG: eca:ECA4224 hypothetical protein YP_002989348.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_002989349.1 KEGG: eca:ECA4226 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase YP_002989350.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002989351.1 KEGG: eca:ECA4228 acetolactate synthase 2 regulatory subunit YP_002989352.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002989353.1 KEGG: eca:ECA4230 magnesium-chelatase; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA YP_002989354.1 PFAM: protein of unknown function DUF413; KEGG: eca:ECA4231 hypothetical protein YP_002989355.1 negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_002989356.1 KEGG: stm:PSLT042 integrase protein YP_002989357.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002989358.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_002989359.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002989360.1 PFAM: protein of unknown function DUF1422; KEGG: eca:ECA4240 hypothetical protein YP_002989361.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_002989362.1 catalyzes the conversion of NADPH to NADH YP_002989363.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_002989364.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_002989365.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002989366.1 KEGG: eca:ECA4252 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_002989367.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002989368.1 TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: set:SEN3886 50S ribosomal protein L31 YP_002989369.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002989370.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_002989371.1 TIGRFAM: cell division protein FtsN; PFAM: sporulation domain protein; KEGG: eca:ECA4260 cell division protein FtsN YP_002989372.1 heat shock protein involved in degradation of misfolded proteins YP_002989373.1 KEGG: yen:YE0104 ATP-dependent protease ATP-binding subunit; TIGRFAM: heat shock protein HslVU, ATPase HslU; PFAM: ATPase AAA-2 domain protein; ATPase AAA; SMART: ATPase AAA YP_002989374.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002989375.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002989376.1 PFAM: protein of unknown function DUF904; KEGG: yps:YPTB0089 hypothetical protein YP_002989377.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: eca:ECA4266 glycerol uptake facilitator protein YP_002989378.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: spe:Spro_4798 glycerol kinase YP_002989379.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002989380.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: esa:ESA_03881 ferredoxin-NADP reductase YP_002989381.1 PFAM: protein of unknown function DUF805; KEGG: eca:ECA4270 hypothetical protein YP_002989382.1 PFAM: protein of unknown function DUF1454; KEGG: eca:ECA4271 hypothetical protein YP_002989383.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002989384.1 KEGG: spe:Spro_1528 bacterial alkaline phosphatase; PFAM: alkaline phosphatase; SMART: alkaline phosphatase YP_002989385.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_002989386.1 TIGRFAM: N-carbamoylputrescine amidase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eca:ECA4274 carbon-nitrogen hydrolase YP_002989387.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002989388.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_002989389.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: esa:ESA_00670 hypothetical protein YP_002989390.1 PFAM: NUDIX hydrolase; KEGG: sea:SeAg_B4799 NUDIX hydrolase YP_002989391.1 PFAM: Tail Collar domain protein; KEGG: ecz:ECS88_2817 variable tail fiber protein YP_002989392.1 PFAM: tail assembly chaperone gp38; KEGG: eca:ECA3742 bacteriophage tail fiber assembly protein YP_002989393.1 PFAM: Tail Collar domain protein; KEGG: eca:ECA2608 bacteriophage variable tail fiber protein H YP_002989394.1 TIGRFAM: phage tail protein I; KEGG: eca:ECA2609 phage tail protein I YP_002989395.1 PFAM: Baseplate J family protein; KEGG: eca:ECA2610 phage baseplate assembly protein J YP_002989396.1 PFAM: GPW/gp25 family protein; KEGG: eca:ECA2611 phage baseplate assembly protein W YP_002989397.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: eca:ECA2612 baseplate assembly protein V YP_002989398.1 TIGRFAM: phage virion morphogenesis protein; PFAM: virion morphogenesis ( tail completion) protein; KEGG: sbo:SBO_1399 phage tail completion protein YP_002989399.1 PFAM: P2 phage tail completion R family protein; KEGG: ecg:E2348C_1821 predicted tail protein YP_002989400.1 KEGG: ecq:ECED1_0887 hypothetical protein; exported protein YP_002989401.1 PFAM: glycoside hydrolase family 24; KEGG: ecq:ECED1_0888 prophage lysozyme responsible for host cell lysis (muramidase) (endolysin) YP_002989402.1 KEGG: ecq:ECED1_0889 hypothetical protein YP_002989403.1 PFAM: tail X family protein; KEGG: ecq:ECED1_0890 tail protein X from prophage YP_002989404.1 PFAM: head completion protein; KEGG: ecq:ECED1_0891 phage head completion protein L YP_002989405.1 PFAM: small terminase subunit; KEGG: eca:ECA2620 phage terminase, endonuclease small subunit M YP_002989406.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: eca:ECA2621 major phage capsid protein N precursor YP_002989407.1 PFAM: capsid scaffolding; KEGG: eca:ECA2622 capsid scaffolding protein O YP_002989408.1 PFAM: protein of unknown function DUF264; terminase ATPase; KEGG: eck:EC55989_2105 terminase, ATPase (GpP) YP_002989409.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: eca:ECA2624 phage capsid portal protein Q YP_002989410.1 PFAM: protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pmr:PMI1994 transcriptional regulator YP_002989411.1 KEGG: plu:plu3938 hypothetical protein YP_002989412.1 PFAM: replication gene A; KEGG: ypb:YPTS_3589 replication gene A YP_002989413.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: ent:Ent638_1349 phosphoadenosine phosphosulfate reductase YP_002989414.1 KEGG: ypy:YPK_0888 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_002989415.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: ent:Ent638_3507 TraR/DksA family transcriptional regulator YP_002989416.1 KEGG: eca:ECA2631 hypothetical protein YP_002989417.1 KEGG: ypb:YPTS_3592 hypothetical protein YP_002989419.1 KEGG: eca:ECA2634 hypothetical protein YP_002989420.1 KEGG: ecm:EcSMS35_4308 regulatory protein Cox YP_002989421.1 KEGG: conserved hypothetical protein YP_002989423.1 PFAM: integrase family protein; KEGG: ecm:EcSMS35_4307 site-specific recombinase, phage integrase family YP_002989424.1 KEGG: eca:ECA4310 stress resistance protein YP_002989425.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_002989426.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002989427.1 KEGG: eca:ECA4313 hypothetical protein YP_002989428.1 KEGG: eca:ECA4314 hypothetical protein YP_002989429.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: eca:ECA4315 RNA-methyltransferase YP_002989430.1 KEGG: eca:ECA4316 hypothetical protein YP_002989431.1 PFAM: Auxin Efflux Carrier; KEGG: eca:ECA4317 transporter YP_002989432.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002989433.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_002989434.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_002989435.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_002989436.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_002989437.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4332 methyl-accepting chemotaxis protein YP_002989438.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: aav:Aave_4495 methyl-accepting chemotaxis sensory transducer YP_002989439.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4335 methyl-accepting chemotaxis protein YP_002989440.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4335 methyl-accepting chemotaxis protein YP_002989441.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4335 methyl-accepting chemotaxis protein YP_002989442.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA4336 aminotransferase YP_002989443.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transporter; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002989444.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002989445.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002989446.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_002989447.1 PFAM: extracellular ligand-binding receptor; KEGG: eca:ECA4341 leucine-specific binding protein YP_002989448.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4342 acetyltransferase YP_002989449.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002989450.1 ABC transporter membrane protein YP_002989451.1 KEGG: sgl:SG0085 cell division protein FtsE; TIGRFAM: type II (general) Secretory Pathway (IISP) Family protein; cell division ATP-binding protein FtsE; PFAM: ABC transporter; SMART: ATPase AAA YP_002989452.1 KEGG: eca:ECA4346 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA YP_002989453.1 catalyzes the methylation of 16S rRNA at position G966 YP_002989454.1 PFAM: protein of unknown function DUF1145; KEGG: eca:ECA4348 hypothetical protein YP_002989455.1 PFAM: Domain of unknown function DUF1820; KEGG: eca:ECA4350 hypothetical protein YP_002989456.1 PFAM: YhhN family protein; KEGG: eca:ECA4351 hypothetical protein YP_002989457.1 PFAM: SirA family protein; KEGG: eca:ECA4353 cell developmental protein SirA YP_002989458.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: eca:ECA4354 hypothetical protein YP_002989459.1 KEGG: kpe:KPK_0275 lipoprotein YP_002989460.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4358 hypothetical protein YP_002989461.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: spe:Spro_4744 ribonuclease YP_002989462.1 PFAM: PfkB domain protein; KEGG: eca:ECA4360 2-dehydro-3-deoxygluconokinase YP_002989464.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA4361 peptidase YP_002989465.1 involved in the transport of C4-dicarboxylates across the membrane YP_002989466.1 PFAM: glycoside hydrolase family 8; KEGG: eta:ETA_33880 minor endoglucanase Y precursor (endo-1,4-beta-glucanase Y) YP_002989467.1 KEGG: eta:ETA_33890 cellulose synthase operon protein D YP_002989468.1 PFAM: cellulose synthase operon C domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: eta:ETA_33900 cellulose synthase operon protein C YP_002989469.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_002989470.1 TIGRFAM: cellulose synthase catalytic subunit (UDP-forming); PFAM: glycosyl transferase family 2; type IV pilus assembly PilZ; KEGG: eta:ETA_33920 cellulose synthase, cellulose synthase operon protein A YP_002989471.1 TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: cobyrinic acid ac-diamide synthase; KEGG: ent:Ent638_3941 hypothetical protein YP_002989472.1 KEGG: ent:Ent638_3942 hypothetical protein YP_002989473.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA4384 amino acid metabolite efflux pump YP_002989475.1 PFAM: hypothetical protein; KEGG: eca:ECA3869 transcriptional regulator YP_002989476.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_C_1587 hypothetical protein YP_002989477.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: spe:Spro_0112 transcriptional regulator YP_002989478.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002989479.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transporter DppABCDF YP_002989480.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4392 dipeptide transporter YP_002989481.1 transports peptides consisting of two or three amino acids YP_002989482.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4394 periplasmic dipeptide transporter YP_002989483.1 PFAM: citrate carrier protein; KEGG: eca:ECA4395 Na(+)-malate symporter YP_002989484.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_002989485.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002989487.1 TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: kpe:KPK_2908 tartrate carrier YP_002989488.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_002989489.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_002989490.1 PFAM: protein of unknown function DUF1375; KEGG: eca:ECA4404 hypothetical protein YP_002989491.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sgl:SG2371 transcriptional regulator YP_002989492.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: sed:SeD_A0233 major facilitator family transporter YP_002989493.1 KEGG: pmr:PMI2938 hypothetical protein YP_002989494.1 PFAM: dihydrodipicolinate synthetase; KEGG: pmr:PMI2939 dihydrodipicolinate synthase-family protein YP_002989495.1 PFAM: L-fucose isomerase _2 domain protein; KEGG: pmr:PMI2940 hypothetical protein YP_002989496.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase FGGY; KEGG: pmr:PMI2941 probable carbohydrate kinase YP_002989498.1 KEGG: eca:ECA4405 hypothetical protein YP_002989499.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA4406 hypothetical protein YP_002989500.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_002989501.1 PFAM: chemotaxis sensory transducer; Cache domain protein; SMART: chemotaxis sensory transducer; KEGG: esa:ESA_pESA3p05532 hypothetical protein YP_002989502.1 PFAM: UspA domain protein; KEGG: esa:ESA_04226 hypothetical protein YP_002989504.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002989505.1 PFAM: phosphate transporter; KEGG: eca:ECA0048 low-affinity inorganic phosphate transporter YP_002989506.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: eca:ECA0047 hypothetical protein YP_002989507.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate YP_002989509.1 TIGRFAM: D-serine ammonia-lyase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: bvi:Bcep1808_3327 D-serine dehydratase YP_002989510.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vvu:VV1_2510 acetyltransferase YP_002989511.1 KEGG: bte:BTH_I2306 hypothetical protein YP_002989512.1 PFAM: sodium symporter; KEGG: dac:Daci_1101 bile acid:sodium symporter YP_002989513.1 PFAM: histidine acid phosphatase; KEGG: eca:ECA4198 exported phosphatase YP_002989514.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3375 transporter YP_002989515.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3376 LysR family transcriptional regulator YP_002989516.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpe:KPK_2238 transporter major facilitator family YP_002989517.1 KEGG: asa:ASA_1096 hypothetical protein YP_002989518.1 PFAM: AMP-dependent synthetase and ligase; KEGG: aha:AHA_3218 long-chain acyl-CoA synthetases YP_002989519.1 KEGG: aha:AHA_3219 long-chain acyl-CoA synthetase YP_002989520.1 PFAM: short-chain dehydrogenase/reductase SDR; Male sterility domain; KEGG: asa:ASA_1093 short chain dehydrogenase YP_002989521.1 KEGG: aha:AHA_3221 hypotheticalprotein YP_002989522.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_002989523.1 Essential for recycling GMP and indirectly, cGMP YP_002989524.1 TIGRFAM: DNA-directed RNA polymerase subunit omega; PFAM: RNA polymerase Rpb6; KEGG: see:SNSL254_A4021 DNA-directed RNA polymerase, omega subunit YP_002989525.1 KEGG: eca:ECA0038 bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; amino acid-binding ACT domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_002989526.1 specifically modifies tRNA at position G18 YP_002989527.1 catalyzes branch migration in Holliday junction intermediates YP_002989528.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: eta:ETA_00380 purine/xanthine transporter YP_002989529.1 PFAM: AsmA family protein; KEGG: eca:ECA0034 hypothetical protein YP_002989530.1 TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0033 GNAT family acetyltransferase YP_002989531.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine YP_002989532.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: eca:ECA0031 phosphatase YP_002989533.1 TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: eum:ECUMN_4395 GTP-binding protein YP_002989534.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002989536.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_002989537.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_002989538.1 KEGG: ecx:EcHS_A4094 hypothetical protein YP_002989539.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002989540.1 PFAM: protein of unknown function DUF414; KEGG: eca:ECA0024 hypothetical protein YP_002989541.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002989542.1 KEGG: eca:ECA0021 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; 3'-5' exonuclease; Helix-hairpin-helix domain protein class 2 YP_002989543.1 PFAM: DSBA oxidoreductase; KEGG: eca:ECA0020 periplasmic protein disulfide isomerase I YP_002989544.1 PFAM: aminoglycoside phosphotransferase; KEGG: yen:YE0019 serine/threonine protein kinase YP_002989545.1 PFAM: protein of unknown function DUF1040; KEGG: eca:ECA0018 hypothetical protein YP_002989546.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002989547.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: ecr:ECIAI1_4055 molybdopterin-guanine dinucleotide biosynthesis protein B YP_002989548.1 DNA-binding transcriptional repressor of ribose metabolism YP_002989549.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002989550.1 periplasmic substrate-binding component of the ATP-dependent ribose transporter YP_002989551.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002989552.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_002989553.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002989554.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002989555.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_002989556.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002989557.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002989558.1 PFAM: flavodoxin/nitric oxide synthase; KEGG: eca:ECA0001 flavodoxin YP_002989559.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002989560.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: eca:ECA4520 glucose-inhibited division protein B YP_002989561.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_002989562.1 TIGRFAM: ATP synthase F0 subunit alpha; PFAM: H+transporting two-sector ATPase subunit alpha; KEGG: sgl:SG2408 F0F1 ATP synthase subunit A YP_002989563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002989564.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002989565.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit delta is part of the catalytic core of the ATP synthase complex YP_002989566.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002989567.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002989568.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002989569.1 TIGRFAM: ATP synthase F1 subunit epsilon; PFAM: H+transporting two-sector ATPase delta/subunit epsilon; KEGG: eca:ECA4511 F0F1 ATP synthase subunit epsilon YP_002989570.1 KEGG: eca:ECA4510 exopolygalacturonate lyase YP_002989571.1 KEGG: ypg:YpAngola_A4200 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: nucleotidyl transferase; transferase YP_002989572.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002989573.1 TIGRFAM: phosphate ABC transporter periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA4477 phosphate transporter subunit YP_002989574.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002989575.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002989576.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002989577.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002989578.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4470 extracellular solute-binding protein YP_002989579.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_0018 polar amino acid ABC transporter inner membrane subunit YP_002989580.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_0019 polar amino acid ABC transporter inner membrane subunit YP_002989581.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_002989582.1 PFAM: xanthine/uracil/vitamin C permease; KEGG: eca:ECA4464 permease YP_002989583.1 KEGG: eca:ECA4463 hypothetical protein YP_002989584.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA4462 electron transporter YP_002989585.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_002989586.1 PFAM: Curli production assembly/transport component CsgG; KEGG: eca:ECA4460 lipoprotein YP_002989587.1 KEGG: eca:ECA4459 lipoprotein YP_002989588.1 PFAM: protein of unknown function DUF799; KEGG: eca:ECA4458 lipoprotein YP_002989589.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_002989590.1 PFAM: glycosyl transferase family 2; KEGG: ent:Ent638_2078 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_002989591.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_002989592.1 PFAM: polysaccharide deacetylase; KEGG: ent:Ent638_2076 polysaccharide deacetylase YP_002989593.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_002989594.1 KEGG: eta:ETA_23780 inner membrane protein YP_002989595.1 KEGG: yen:YE2186 hypothetical protein YP_002989596.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eta:ETA_17400 GNAT-family acetyltransferase YP_002989597.1 KEGG: prw:PsycPRwf_1040 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase YP_002989598.1 TIGRFAM: methyltransferase FkbM family; KEGG: noc:Noc_0747 methyltransferase FkbM YP_002989599.1 PFAM: secretion protein HlyD; KEGG: plu:plu2645 hypothetical protein YP_002989600.1 PFAM: outer membrane efflux protein; KEGG: plu:plu2646 hypothetical protein YP_002989601.1 PFAM: protein of unknown function DUF214; KEGG: plu:plu2647 hypothetical protein YP_002989602.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ppw:PputW619_0892 ABC transporter YP_002989603.1 KEGG: ent:Ent638_0389 hypothetical protein YP_002989604.1 KEGG: plu:plu2640 hypothetical protein YP_002989605.1 TIGRFAM: HipA N-terminal domain protein; KEGG: plu:plu4900 HipA protein YP_002989606.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu4901 HipB protein YP_002989607.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002989608.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002989609.1 PFAM: protein of unknown function DUF37; KEGG: sgl:SG2430 hypothetical protein YP_002989610.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002989611.1 in Escherichia coli transcription of this gene is enhanced by polyamines