-- dump date 20140619_065522 -- class Genbank::CDS -- table cds_note -- id note YP_003002374.1 KEGG: eca:ECA4441 chromosomal replication initiation protein; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: Chromosomal replication initiator DnaA domain; AAA ATPase YP_003002375.1 binds the polymerase to DNA and acts as a sliding clamp YP_003002376.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_003002377.1 negatively supercoils closed circular double-stranded DNA YP_003002378.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4437 MFS efflux transporter YP_003002379.1 predicted SAM-dependent methyltransferase YP_003002380.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: eca:ECA0055 oligopeptidase A YP_003002381.1 KEGG: eca:ECA0060 hypothetical protein YP_003002382.1 PFAM: protein of unknown function DUF519; KEGG: eca:ECA0061 hypothetical protein YP_003002383.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_003002384.1 PFAM: regulator of RNA terminal phosphate cyclase; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: esa:ESA_00062 hypothetical protein YP_003002385.1 PFAM: band 7 protein; KEGG: ect:ECIAI39_4422 hypothetical protein YP_003002386.1 PFAM: protein of unknown function UPF0027; KEGG: plu:plu4307 protein RtcB YP_003002387.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_003002388.1 PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: esa:ESA_00303 hypothetical protein YP_003002389.1 KEGG: esa:ESA_00304 hypothetical protein YP_003002390.1 KEGG: esa:ESA_00305 hypothetical protein YP_003002391.1 PFAM: protein of unknown function DUF161; KEGG: ppu:PP_0642 hypothetical protein YP_003002392.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: reu:Reut_C6217 AsnC family transcriptional regulator YP_003002393.1 PFAM: aminotransferase class V; KEGG: pzu:PHZ_c3273 phosphoserine aminotransferase YP_003002394.1 PFAM: GCN5-related N-acetyltransferase; KEGG: spe:Spro_2129 GCN5-related N-acetyltransferase YP_003002395.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: dac:Daci_0312 MarR family transcriptional regulator YP_003002396.1 KEGG: ypg:YpAngola_A3875 hypothetical protein YP_003002397.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_003002398.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: cak:Caul_0574 LysR family transcriptional regulator YP_003002399.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: nar:Saro_1864 alcohol dehydrogenase YP_003002400.1 TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: eca:ECA0070 hypothetical protein YP_003002401.1 PFAM: Luciferase-like monooxygenase; KEGG: eca:ECA0071 putative monooxygenase YP_003002402.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0072 ABC transporter ATP-binding protein YP_003002403.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0073 ABC transporter permease protein YP_003002404.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0074 ABC transporter permease protein YP_003002405.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0075 ABC-type transporter, substrate binding protein YP_003002406.1 PFAM: protein of unknown function DUF1471; KEGG: plu:plu4502 hypothetical protein YP_003002407.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_003002408.1 KEGG: eca:ECA4385 hypothetical protein YP_003002409.1 PFAM: virulence-associated protein D (VapD) conserved region; KEGG: hsm:HSM_1448 virulence-associated protein D (VapD) region YP_003002410.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: eca:ECA0078 2-hydroxyacid dehydrogenase YP_003002411.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0081 hypothetical protein YP_003002412.1 KEGG: eca:ECA0082 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_003002413.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA0083 hypothetical protein YP_003002414.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003002415.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003002416.1 KEGG: par:Psyc_1209 hypothetical protein YP_003002417.1 KEGG: cja:CJA_2723 UreA amidolyase homolog; TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Allophanate hydrolase subunit 1; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; SMART: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1 YP_003002418.1 TIGRFAM: urea carboxylase-associated protein 1; KEGG: abo:ABO_1891 hypothetical protein YP_003002419.1 TIGRFAM: urea carboxylase-associated protein 2; KEGG: sde:Sde_1125 5'-3' exonuclease YP_003002420.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bph:Bphy_3976 ABC transporter related YP_003002421.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cja:CJA_2719 ABC transporter, permease protein YP_003002422.1 TIGRFAM: ABC transporter periplasmic binding protein, urea carboxylase region; KEGG: cja:CJA_2718 ABC transporter, periplasmic substrate-binding protein YP_003002423.1 KEGG: eca:ECA0086 hypothetical protein YP_003002424.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: eca:ECA0087 PTS system, mannitol-specific IIABC component YP_003002425.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0088 mannitol-1-phosphate 5-dehydrogenase YP_003002426.1 Acts as a repressor of the mtlAD operon YP_003002427.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0091 methyl-accepting chemotaxis protein YP_003002428.1 PFAM: manganese and iron superoxide dismutase; KEGG: eca:ECA0092 superoxide dismutase YP_003002429.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_003002430.1 PFAM: Aldehyde Dehydrogenase; KEGG: eca:ECA0094 aldehyde dehydrogenase B YP_003002431.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: eca:ECA0096 xylulose kinase YP_003002432.1 catalyzes the interconversion of D-xylose to D-xylulose YP_003002433.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_003002434.1 with XylFH is part of the high affinity xylose ABC transporter YP_003002435.1 PFAM: inner-membrane translocator; KEGG: eca:ECA0100 xylose transport system permease YP_003002436.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA0101 xylose operon regulatory protein YP_003002437.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA0102 hypothetical protein YP_003002438.1 PFAM: protein of unknown function DUF156; KEGG: asa:ASA_0625 hypothetical protein YP_003002439.1 membrane protein conferring nickel and cobalt resistance YP_003002440.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_003002441.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmn:BMA10247_0906 MarR family transcriptional regulator YP_003002442.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ecm:EcSMS35_A0154 drug/metabolite transporter YP_003002443.1 PFAM: Indigoidine synthase A family protein; KEGG: plu:plu2187 hypothetical protein YP_003002444.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: plu:plu2182 hypothetical protein YP_003002445.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; KEGG: plu:plu2186 hypothetical protein YP_003002446.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu0753 hypothetical protein YP_003002449.1 KEGG: pfo:Pfl01_3541 multi anti extrusion protein MatE YP_003002450.1 KEGG: pfl:PFL_0267 hypothetical protein YP_003002451.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: dvl:Dvul_2703 transcription activator, effector binding YP_003002452.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_2119 ABC transporter, ATP-binding protein YP_003002453.1 PFAM: protein of unknown function DUF214; KEGG: cps:CPS_2120 putative ABC transporter, permease protein YP_003002454.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: cps:CPS_2121 sigma-54 dependent DNA-binding response regulator YP_003002455.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: cps:CPS_2122 sensor histidine kinase YP_003002456.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: cbc:CbuK_0411 4'-phosphopantetheinyl transferase YP_003002458.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu0753 hypothetical protein YP_003002460.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: plu:plu0762 hypothetical protein YP_003002461.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: plu:plu0753 hypothetical protein YP_003002463.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: plu:plu0762 hypothetical protein YP_003002464.1 KEGG: pst:PSPTO_4711 coronamic acid synthetase CmaC YP_003002465.1 PFAM: AMP-dependent synthetase and ligase; KEGG: baa:BA_1915 AMP-binding enzyme YP_003002466.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bsu:BSU38500 D-alanine--D-alanyl carrier protein ligase YP_003002468.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mlo:mll6742 long chain acyl-CoA synthetase YP_003002470.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mpo:Mpop_3620 Orn/DAP/Arg decarboxylase 2 YP_003002472.1 PFAM: Autoinducer-binding domain protein; regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: eca:ECA1561 quorum-sensing transcriptional regulator YP_003002473.1 PFAM: autoinducer synthesis protein; KEGG: eca:ECA0105 N-acylhomoserine lactone synthesis protein YP_003002474.1 PFAM: protein of unknown function DUF1471; KEGG: elf:LF82_0232 UPF0379 protein YcfR YP_003002475.1 TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; KEGG: eca:ECA4272 triosephosphate isomerase YP_003002476.1 PFAM: protein of unknown function DUF1454; KEGG: eca:ECA4271 hypothetical protein YP_003002477.1 PFAM: protein of unknown function DUF805; KEGG: eca:ECA4270 hypothetical protein YP_003002478.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: esa:ESA_03881 ferredoxin-NADP reductase YP_003002479.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_003002480.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: eca:ECA4267 glycerol kinase YP_003002481.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: eca:ECA4266 glycerol uptake facilitator protein YP_003002482.1 PFAM: protein of unknown function DUF904; KEGG: eca:ECA4265 hypothetical protein YP_003002483.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_003002484.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_003002485.1 KEGG: eca:ECA4262 ATP-dependent protease ATP-binding subunit; TIGRFAM: heat shock protein HslVU, ATPase subunit HslU; PFAM: ATPase AAA-2 domain protein; SMART: AAA ATPase YP_003002486.1 heat shock protein involved in degradation of misfolded proteins YP_003002487.1 TIGRFAM: cell division protein FtsN; PFAM: Sporulation domain protein; KEGG: eca:ECA4260 cell division protein FtsN YP_003002488.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_003002489.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_003002490.1 TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: stm:STM4096 50S ribosomal protein L31 YP_003002491.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_003002492.1 KEGG: eca:ECA4252 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_003002493.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_003002494.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_B0832 putative oxidoreductase YP_003002495.1 PFAM: regulatory protein TetR; KEGG: ara:Arad_2384 transcriptional regulator protein YP_003002497.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_003002498.1 TIGRFAM: glutaredoxin-family domain protein; PFAM: Redoxin domain protein; glutaredoxin; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: yen:YE0132 putative peroxiredoxin/glutaredoxin family protein YP_003002499.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_003002500.1 catalyzes the conversion of NADPH to NADH YP_003002501.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_003002502.1 PFAM: protein of unknown function DUF1422; KEGG: eca:ECA4240 hypothetical protein YP_003002503.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_003002504.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_003002505.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_003002506.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_003002507.1 PFAM: protein of unknown function DUF413; KEGG: eca:ECA4231 hypothetical protein YP_003002508.1 KEGG: eca:ECA4230 magnesium-chelatase; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_003002509.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: spe:Spro_4761 major facilitator transporter YP_003002510.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_003002511.1 KEGG: eca:ECA4228 acetolactate synthase 2 regulatory subunit YP_003002512.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_003002513.1 KEGG: ect:ECIAI39_3015 dihydroxyacid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase YP_003002514.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_003002515.1 KEGG: eca:ECA4224 hypothetical protein YP_003002516.1 KEGG: eca:ECA4223 hypothetical protein YP_003002517.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_003002518.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_003002520.1 TIGRFAM: sodium/proline symporter; SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: eca:ECA4218 sodium/proline symporter YP_003002521.1 TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase; KEGG: spe:Spro_2931 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_003002522.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: eca:ECA4216 peptidyl-prolyl cis-trans isomerase C YP_003002523.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_003002524.1 PFAM: glycoside hydrolase family 28; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: yen:YE0164 exo-poly-alpha-D-galacturonosidase precursor YP_003002525.1 PFAM: glycoside hydrolase family 28; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; Parallel beta-helix repeat; KEGG: yen:YE0164 exo-poly-alpha-D-galacturonosidase precursor YP_003002526.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_003002527.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_003002528.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: eta:ETA_01950 thioredoxin 1 YP_003002529.1 KEGG: cko:CKO_00124 transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; Ribonuclease B OB region domain; Rho termination factor domain protein; Rho termination factor RNA-binding; SMART: Cold shock protein; AAA ATPase YP_003002530.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: eca:ECA4210 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_003002531.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_003002532.1 KEGG: spe:Spro_0163 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase YP_003002533.1 TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: yps:YPTB0171 UDP-N-acetyl-D-mannosamine dehydrogenase YP_003002534.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4205 TDP-fucosamine acetyltransferase YP_003002535.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_003002536.1 PFAM: polysaccharide biosynthesis protein; KEGG: eca:ECA4203 entero common antigen biosynthesis protein YP_003002537.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_003002538.1 enterobacterial common antigen polymerase YP_003002539.1 KEGG: eca:ECA4200 putative UDP-N-acetyl-D-mannosaminuronic acid transferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF YP_003002540.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_003002541.1 KEGG: aha:AHA_0731 steroid delta-isomerase domain-containing protein YP_003002542.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_003002543.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4196 putative acetyltransferase YP_003002544.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4195 putative amino-acid ABC transporter binding protein YP_003002545.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4194 amino-acid ABC transporter permease protein YP_003002546.1 PFAM: ABC transporter related; SMC domain protein; SMART: AAA ATPase; KEGG: eca:ECA4193 putative amino-acid ABC transporter ATP-binding protein YP_003002547.1 KEGG: eca:ECA4192 putative peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_003002548.1 KEGG: eca:ECA4191 putative protoheme IX biogenesis protein; TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_003002549.1 PFAM: protein of unknown function DUF513 hemX; KEGG: eca:ECA4190 putative uroporphyrinogen III C-methyltransferase YP_003002550.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_003002551.1 KEGG: ent:Ent638_3987 porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase YP_003002552.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_003002553.1 TIGRFAM: iron donor protein CyaY; PFAM: Frataxin family protein; KEGG: eca:ECA4185 frataxin-like protein YP_003002554.1 KEGG: eca:ECA4184 putative lipoprotein YP_003002555.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_003002556.1 PFAM: protein of unknown function DUF484; KEGG: eca:ECA4182 hypothetical protein YP_003002557.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003002558.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ecg:E2348C_4112 predicted hydrolase YP_003002559.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_003002560.1 responsible for the influx of magnesium ions YP_003002561.1 TIGRFAM: membrane protein AbrB duplication; PFAM: putative ammonia monooxygenase; KEGG: eca:ECA4176 hypothetical protein YP_003002562.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA4175 hypothetical protein YP_003002563.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA4174 hypothetical protein YP_003002564.1 catalyzes the hydrolysis of phosphatidylcholine YP_003002565.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_003002566.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4171 threonine efflux system YP_003002567.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4170 homoserine/homoserine lactone efflux protein YP_003002568.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_003002569.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: eca:ECA4168 putative sugar phosphatase YP_003002570.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_003002571.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_003002572.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_003002573.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_003002574.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_003002575.1 PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: eca:ECA4162 hypothetical protein YP_003002576.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003002577.1 KEGG: eca:ECA3946 hypothetical protein YP_003002578.1 PFAM: protein of unknown function DUF323; KEGG: plu:plu0187 CpmF protein involved in carbapenem resistance YP_003002579.1 KEGG: pmr:PMI1554 hypothetical protein YP_003002580.1 KEGG: plu:plu0880 CpmJ protein YP_003002581.1 PFAM: ferredoxin; KEGG: plu:plu0186 CpmE protein involved in carbapenem biosynthesis YP_003002582.1 PFAM: Proline dehydrogenase; KEGG: plu:plu0185 CpmD protein involved in carbapenem biosynthesis YP_003002583.1 PFAM: Taurine catabolism dioxygenase TauD/TfdA; KEGG: plu:plu0184 CpmC protein involved in carbapenem biosynthesis YP_003002584.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: plu:plu0183 CpmB protein involved in carbapenem biosynthesis YP_003002585.1 PFAM: asparagine synthase; KEGG: plu:plu0182 CpmA protein involved in carbapenem biosynthesis YP_003002586.1 KEGG: plu:plu4519 IS427 family transposase YP_003002587.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: esa:ESA_04301 hypothetical protein YP_003002588.1 KEGG: eca:ECA1839 gluconokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_003002589.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: spe:Spro_4651 gluconate transporter YP_003002590.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_003002591.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_003002592.1 PFAM: NikR nickel binding; CopG domain protein DNA-binding domain protein; KEGG: azo:azo3128 nickel responsive regulator YP_003002593.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yen:YE3823 major cold shock protein YP_003002594.1 PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; KEGG: eca:ECA4152 putative two-component system sensor kinase YP_003002595.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_003002596.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_003002597.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_003002598.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_003002599.1 KEGG: eca:ECA4147 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_003002600.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_003002601.1 KEGG: eca:ECA4139 thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein YP_003002602.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_003002603.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_003002604.1 KEGG: eca:ECA4136 maltodextrin phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_003002605.1 amylomaltase; acts to release glucose from maltodextrins YP_003002606.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_003002607.1 KEGG: spe:Spro_4633 gluconate periplasmic binding protein YP_003002608.1 KEGG: eca:ECA4132 putative biotin biosynthesis protein; TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold YP_003002609.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_003002610.1 PFAM: protein of unknown function DUF1493; KEGG: yps:YPTB1663 putative acyl carrier protein YP_003002611.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: eca:ECA4122 putative RNA binding protein YP_003002612.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: eca:ECA4119 putative acyltransferase YP_003002613.1 PFAM: sulfatase; KEGG: asu:Asuc_0556 sulfatase YP_003002614.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shm:Shewmr7_3890 transcription elongation factor GreB YP_003002615.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_003002616.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_003002617.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_003002619.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_003002620.1 PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: ses:SARI_04118 ribosome-associated heat shock protein HSP15 YP_003002621.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4103 putative hydrolase YP_003002622.1 PFAM: Intracellular growth attenuator IgaA; KEGG: eca:ECA4102 intracellular growth attenuator protein YP_003002623.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_003002624.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_003002626.1 KEGG: eca:ECA4098 hypothetical protein YP_003002627.1 PFAM: Fimbrial assembly family protein; KEGG: eca:ECA4097 hypothetical protein YP_003002628.1 KEGG: eca:ECA4096 hypothetical protein YP_003002629.1 KEGG: eca:ECA4095 hypothetical protein YP_003002630.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_003002631.1 PFAM: shikimate kinase; KEGG: esa:ESA_04351 shikimate kinase I YP_003002632.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_003002633.1 PFAM: Sporulation domain protein; KEGG: eca:ECA4091 hypothetical protein YP_003002634.1 KEGG: eca:ECA4090 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_003002635.1 KEGG: eca:ECA4089 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase YP_003002636.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_003002637.1 KEGG: eca:ECA4087 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib YP_003002638.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA4077 putative mandelate racemase / muconate lactonizing enzyme YP_003002639.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: eca:ECA4071 peptidyl-prolyl cis-trans isomerase A (rotamase A) YP_003002640.1 KEGG: eca:ECA4070 pectate lyase YP_003002641.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: eca:ECA4069 pectate lyase III YP_003002642.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: eca:ECA4069 pectate lyase III YP_003002643.1 KEGG: vvu:VV2_1425 glutamate decarboxylase YP_003002644.1 KEGG: fph:Fphi_0374 hypothetical protein YP_003002645.1 KEGG: dal:Dalk_2018 PAS/PAC sensor hybrid histidine kinase YP_003002646.1 PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_1856 putative cyanate permease YP_003002647.1 PFAM: glycoside hydrolase family 19; KEGG: pfl:PFL_3798 chitinase domain-containing protein YP_003002648.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: yen:YE2922 putative protease YP_003002650.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: smt:Smal_2105 putative sigma54 specific transcriptional regulator YP_003002651.1 PFAM: protein of unknown function DUF891; KEGG: esa:ESA_03838 hypothetical protein YP_003002652.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu0900 hypothetical protein YP_003002653.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: yen:YE3958 para-aminobenzoate synthase component II YP_003002654.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_003002655.1 negative regulator of ulaG and ulaABCDEF YP_003002656.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_003002657.1 KEGG: ppr:PBPRB0271 putative L-ascorbate 6-phosphate lactonase YP_003002658.1 PFAM: putative sugar-specific permease SgaT/UlaA; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ppr:PBPRB0273 ascorbate-specific PTS system enzyme IIC/IIB YP_003002659.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: vvy:VVA1605 PTS system, IIA component YP_003002660.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003002661.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_003002662.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_003002663.1 PFAM: OsmC family protein; KEGG: efe:EFER_3329 hypothetical protein YP_003002664.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: eca:ECA4062 phosphoribulokinase YP_003002665.1 PFAM: protein of unknown function UPF0270; KEGG: efe:EFER_3326 hypothetical protein YP_003002666.1 PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA4060 putative hydrolase YP_003002667.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4059 hypothetical protein YP_003002668.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA4058 putative ABC transporter ATP-binding protein YP_003002669.1 required for KefB activity YP_003002670.1 involved in potassium efflux YP_003002671.1 KEGG: eca:ECA4055 hypothetical protein YP_003002672.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_3766 FKBP-type peptidyl-prolyl cis-trans isomerase YP_003002673.1 TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region; KEGG: eta:ETA_25540 putative ethanolamin permease YP_003002674.1 PFAM: aminoglycoside phosphotransferase; KEGG: eta:ETA_25530 hypothetical protein YP_003002675.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eta:ETA_25520 AraC family transcriptional regulator YP_003002676.1 PFAM: SlyX family protein; KEGG: eta:ETA_31750 host factor for lysis of phiX174 infection SlyX YP_003002677.1 rotamase YP_003002678.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA4045 sensor protein BasS/PmrB YP_003002679.1 response regulator in two-component regulatory system with BasS YP_003002680.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_003002681.1 PFAM: YheO domain protein; KEGG: eca:ECA4042 putative DNA-binding protein YP_003002682.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003002683.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003002684.1 TIGRFAM: sulfur relay protein TusB/DsrH; PFAM: DsrH family protein; KEGG: eca:ECA4039 putative intracellular sulfur oxidation protein YP_003002685.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_003002686.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_003002687.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_003002688.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_003002689.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA4034 bacterioferritin-associated ferredoxin YP_003002690.1 iron storage protein YP_003002691.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_003002692.1 PFAM: ribosomal protein L3; KEGG: eca:ECA4031 50S ribosomal protein L3 YP_003002693.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_003002694.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_003002695.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_003002696.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_003002697.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_003002698.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_003002699.1 TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16; KEGG: eca:ECA4024 50S ribosomal protein L16 YP_003002700.1 TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: ypb:YPTS_3882 ribosomal protein L29 YP_003002701.1 PFAM: ribosomal protein S17; KEGG: eum:ECUMN_3784 30S ribosomal subunit protein S17 YP_003002702.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_003002703.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_003002704.1 PFAM: ribosomal protein L5; KEGG: set:SEN3256 50S ribosomal subunit protein L5 YP_003002705.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_003002706.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_003002707.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_003002708.1 binds 5S rRNA along with protein L5 and L25 YP_003002709.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_003002710.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_003002711.1 late assembly protein YP_003002712.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_003002713.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_003002714.1 PFAM: ribosomal protein S13; KEGG: pmr:PMI3277 30S ribosomal protein S13 YP_003002716.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_003002717.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_003002718.1 is a component of the macrolide binding site in the peptidyl transferase center YP_003002719.1 KEGG: kpn:KPN_03693 hypothetical protein YP_003002720.1 PFAM: protein of unknown function DUF331; KEGG: eum:ECUMN_3765 hypothetical protein YP_003002721.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: spe:Spro_4515 large-conductance mechanosensitive channel YP_003002722.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_003002723.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_003002724.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: eca:ECA4000 methionyl-tRNA formyltransferase YP_003002725.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_003002726.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: eca:ECA3998 hypothetical protein YP_003002727.1 PFAM: protein of unknown function DUF494; KEGG: eca:ECA3997 hypothetical protein YP_003002728.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: eca:ECA3996 putative DNA topoisomerase YP_003002729.1 PFAM: SUA5/yciO/yrdC domain; KEGG: eca:ECA3996 putative DNA topoisomerase YP_003002730.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; KEGG: eca:ECA3995 shikimate 5-dehydrogenase YP_003002731.1 PFAM: protein of unknown function DUF1488; KEGG: eca:ECA3994 hypothetical protein YP_003002732.1 KEGG: eca:ECA3993 putative transferase YP_003002733.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_003002734.1 KEGG: esa:ESA_00053 malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase YP_003002735.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: eca:ECA3990 isocitrate lyase YP_003002736.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_003002737.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_003002738.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_003002739.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: eca:ECA3984 putative sodium:sulfate symporter YP_003002740.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; PhoU family protein; KEGG: eca:ECA3983 putative sodium/phosphate cotransporter YP_003002741.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_003002742.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_003002743.1 KEGG: spe:Spro_0410 hypothetical protein YP_003002744.1 KEGG: eca:ECA3977 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_003002745.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_003002746.1 PFAM: protein of unknown function DUF486; KEGG: eca:ECA3974 hypothetical protein YP_003002747.1 PFAM: Lipocalin family protein; KEGG: eca:ECA3973 outer membrane lipoprotein Blc YP_003002748.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_003002749.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003002750.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003002751.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003002752.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003002753.1 PFAM: MscS Mechanosensitive ion channel; KEGG: eca:ECA3967 hypothetical protein YP_003002754.1 KEGG: eca:ECA3966 phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase; PFAM: phosphatidylserine decarboxylase-related YP_003002755.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_003002756.1 PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: spe:Spro_0424 oligoribonuclease YP_003002757.1 KEGG: pen:PSEEN0738 hypothetical protein YP_003002758.1 KEGG: pfo:Pfl01_0146 hypothetical protein YP_003002759.1 PFAM: peptidase M50; KEGG: pfo:Pfl01_0147 peptidase M50 YP_003002760.1 PFAM: Tail Collar domain protein; KEGG: avi:Avi_5259 hypothetical protein YP_003002761.1 PFAM: Ig family protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: hch:HCH_03194 outer membrane protein domain-containing protein YP_003002762.1 KEGG: ppw:PputW619_0676 outer membrane efflux protein YP_003002763.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: yen:YE0409 methyl-accepting chemotaxis protein YP_003002764.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: yen:YE3615 putative methyl-accepting chemotaxis protein YP_003002765.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: spe:Spro_4199 putative DNA-binding transcriptional regulator YP_003002766.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: spe:Spro_4200 amidohydrolase YP_003002767.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: spe:Spro_4201 amidohydrolase YP_003002768.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003002769.1 TIGRFAM: AbgT transporter family; PFAM: AbgT putative transporter; KEGG: plu:plu3724 putative aminobenzoyl-glutamate transporter YP_003002770.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: eca:ECA3168 transcriptional regulator of organic hydroperoxide resistance gene ohr YP_003002771.1 PFAM: OsmC family protein; KEGG: eca:ECA3167 organic hydroperoxide resistance protein YP_003002772.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: psp:PSPPH_3647 lipase YP_003002773.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2153 ABC transporter, ATP-binding protein YP_003002774.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2154 putative ABC transporter, permease YP_003002775.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2155 putative acetyltransferase YP_003002776.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA2156 ABC transporter, substrate binding protein YP_003002777.1 KEGG: eca:ECA2158 hypothetical protein YP_003002778.1 PFAM: Luciferase-like monooxygenase; KEGG: eca:ECA2161 putative luciferase-like monooxygenase YP_003002779.1 KEGG: ent:Ent638_0389 hypothetical protein YP_003002780.1 KEGG: pmr:PMI3401 sugar fermentation stimulation protein YP_003002781.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: eca:ECA0932 permease YP_003002782.1 PFAM: PAS fold-4 domain protein; regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: yen:YE0514 putative transcriptional regulator YP_003002783.1 KEGG: spe:Spro_0470 putative transcriptional regulator, Nlp YP_003002784.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA2866 hypothetical protein YP_003002785.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 putative rhs accessory genetic element YP_003002786.1 PFAM: Domain of unknown function DUF1795; KEGG: eca:ECA2868 hypothetical protein YP_003002787.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; PAAR repeat-containing protein; KEGG: eca:ECA4278 rhs-family protein YP_003002788.1 KEGG: esa:ESA_03890 hypothetical protein YP_003002790.1 PFAM: sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: eca:ECA3435 putative sigma-54 dependent transcriptional regulator YP_003002791.1 PFAM: Relaxase; protein of unknown function DUF1528; KEGG: bpt:Bpet1092 putative helicase YP_003002793.1 KEGG: pla:Plav_3432 hypothetical protein YP_003002794.1 KEGG: pla:Plav_3431 hypothetical protein YP_003002795.1 KEGG: bpt:Bpet1504 hypothetical protein YP_003002796.1 KEGG: net:Neut_0075 hypothetical protein YP_003002797.1 PFAM: protein of unknown function DUF1527; KEGG: eba:ebA2511 hypothetical protein YP_003002798.1 PFAM: protein of unknown function DUF1525; KEGG: ajs:Ajs_2183 hypothetical protein YP_003002799.1 KEGG: maq:Maqu_0393 hypothetical protein YP_003002800.1 PFAM: Domain of unknown function DUF1814; KEGG: maq:Maqu_0394 hypothetical protein YP_003002801.1 KEGG: net:Neut_0086 hypothetical protein YP_003002802.1 KEGG: net:Neut_0087 putative secreted protein YP_003002803.1 KEGG: xcv:XCV2369 putative secreted protein YP_003002804.1 KEGG: har:HEAR2017 putative signal peptide YP_003002805.1 KEGG: net:Neut_0090 putative secreted protein YP_003002806.1 KEGG: ajs:Ajs_1403 hypothetical protein YP_003002807.1 KEGG: bxe:Bxe_A1190 hypothetical protein YP_003002808.1 KEGG: net:Neut_0093 hypothetical protein YP_003002809.1 KEGG: net:Neut_0094 hypothetical protein YP_003002810.1 PFAM: Domain of unknown function DUF1863; KEGG: mgm:Mmc1_3118 hypothetical protein YP_003002811.1 KEGG: azo:azo3763 hypothetical protein YP_003002812.1 KEGG: sse:Ssed_3748 hypothetical protein YP_003002813.1 KEGG: xcv:XCV2376 hypothetical protein YP_003002814.1 KEGG: net:Neut_0098 hypothetical protein YP_003002815.1 KEGG: pla:Plav_3413 hypothetical protein YP_003002816.1 KEGG: har:HEAR2003 putative signal peptide YP_003002817.1 KEGG: ajs:Ajs_1277 putative secreted protein YP_003002818.1 KEGG: net:Neut_0102 hypothetical protein YP_003002819.1 KEGG: ajs:Ajs_1279 putative secreted protein YP_003002820.1 KEGG: mms:mma_3162 integrase YP_003002821.1 KEGG: eca:ECA1658 hypothetical protein YP_003002823.1 SMART: DEAD-like helicase; KEGG: net:Neut_0104 helicase domain-containing protein YP_003002824.1 KEGG: net:Neut_0106 hypothetical protein YP_003002825.1 KEGG: net:Neut_0107 hypothetical protein YP_003002826.1 KEGG: net:Neut_0109 plasmid-related protein YP_003002827.1 KEGG: rme:Rmet_2322 hypothetical protein YP_003002828.1 KEGG: pla:Plav_3399 hypothetical protein YP_003002829.1 KEGG: eba:ebB76 hypothetical protein YP_003002830.1 KEGG: eba:ebA2454 hypothetical protein YP_003002831.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: bxe:Bxe_A1222 C-5 cytosine-specific DNA methylase YP_003002832.1 KEGG: xcv:XCV2287 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein YP_003002834.1 KEGG: xac:XAC2263 hypothetical protein YP_003002835.1 KEGG: xac:XAC2262 hypothetical protein YP_003002836.1 KEGG: ppu:PP_4535 hypothetical protein YP_003002837.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_003002838.1 KEGG: tmz:Tmz1t_0992 hypothetical protein YP_003002839.1 PFAM: Domain of unknown function DUF1845; KEGG: bpt:Bpet1294 hypothetical protein YP_003002840.1 KEGG: bpt:Bpet1293 hypothetical protein YP_003002841.1 KEGG: bpt:Bpet1292 hypothetical protein YP_003002842.1 KEGG: bpt:Bpet1291 hypothetical protein YP_003002843.1 KEGG: bpt:ig_0609 hypothetical protein YP_003002844.1 KEGG: bpt:Bpet1290 hypothetical protein YP_003002845.1 PFAM: Prophage CP4-57 regulatory; KEGG: bpt:Bpet1289 putative transcriptional regulator (phage-related) YP_003002846.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: eca:ECA3947 putative D-isomer specific 2-hydroxyacid dehydrogenase YP_003002847.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA3940 putative 4Fe-4S binding protein YP_003002848.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: eca:ECA3939 hypothetical protein YP_003002849.1 PFAM: protein of unknown function UPF0079; KEGG: spe:Spro_0427 putative ATPase YP_003002850.1 PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; KEGG: eca:ECA3937 N-acetylmuramoyl-L-alanine amidase YP_003002851.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_003002852.1 KEGG: eca:ECA3935 tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase YP_003002853.1 Stimulates the elongation of poly(A) tails YP_003002854.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_003002855.1 KEGG: eca:ECA3932 FtsH protease regulator HflK; TIGRFAM: HflK protein; PFAM: band 7 protein; SMART: band 7 protein YP_003002856.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_003002857.1 KEGG: eca:ECA3930 hypothetical protein YP_003002858.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_003002859.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: eca:ECA3928 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase YP_003002860.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_003002861.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_003002862.1 PFAM: protein of unknown function DUF179; KEGG: eca:ECA3925 hypothetical protein YP_003002863.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_003002864.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_003002865.1 PFAM: Endonuclease I; KEGG: eca:ECA3922 endonuclease YP_003002866.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: eca:ECA3921 hypothetical protein YP_003002867.1 KEGG: eca:ECA3920 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase YP_003002869.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_003002870.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_4593 hypothetical protein YP_003002871.1 TIGRFAM: transketolase; PFAM: Transketolase central region; Transketolase domain protein; KEGG: eca:ECA0861 transketolase YP_003002872.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003002873.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_003002874.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_003002875.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_003002876.1 PFAM: MscS Mechanosensitive ion channel; Conserved TM helix repeat-containing protein; KEGG: eca:ECA3910 putative mechanosensitive ion channel YP_003002877.1 PFAM: Transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: spe:Spro_3928 IclR family transcriptional regulator YP_003002878.1 PFAM: protein of unknown function DUF541; KEGG: eca:ECA3908 hypothetical protein YP_003002879.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_003002880.1 KEGG: eca:ECA3906 ribose-5-phosphate isomerase A; TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase YP_003002881.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_003002882.1 TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: eca:ECA3904 putative zinc-binding dehydrogenase YP_003002883.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3903 LysR family transcriptional activator YP_003002884.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3902 methyl-accepting chemotaxis protein YP_003002885.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_003002886.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_003002887.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: eca:ECA3899 Trp operon repressor YP_003002888.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_003002889.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_003002890.1 PFAM: transcription activator effector binding; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA3896 right origin-binding protein YP_003002891.1 PFAM: CreA family protein; KEGG: eca:ECA3894 hypothetical protein YP_003002892.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: eca:ECA3893 two-component response regulator YP_003002893.1 member of the SPOUT superfamily of methyltransferases YP_003002894.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_003002895.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_003002896.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_003002897.1 PFAM: protein of unknown function DUF328; KEGG: eca:ECA3888 hypothetical protein YP_003002898.1 KEGG: eca:ECA3887 transaldolase B; TIGRFAM: transaldolase; PFAM: Transaldolase YP_003002899.1 KEGG: eca:ECA3886 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003002900.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_003002901.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: eca:ECA3884 putative transport protein YP_003002902.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: eca:ECA3883 hypothetical protein YP_003002903.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_003002904.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_003002905.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_003002906.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_003002907.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_003002908.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_003002909.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_003002910.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_003002911.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: eca:ECA3874 FkbP-type 16 kDa peptidyl-prolyl cis-trans isomerase YP_003002912.1 KEGG: eca:ECA3873 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein YP_003002913.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_003002914.1 KEGG: kpn:KPN_00039 dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase YP_003002915.1 TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: eca:ECA3871 carbamoyl phosphate synthase small subunit YP_003002916.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_003002917.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: spe:Spro_0717 lysine exporter protein LysE/YggA YP_003002918.1 PFAM: protein of unknown function DUF1212; KEGG: eca:ECA3866 hypothetical protein YP_003002919.1 KEGG: eca:ECA3865 hypothetical protein YP_003002920.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_003002921.1 PFAM: protein of unknown function DUF839; KEGG: spe:Spro_0721 hypothetical protein YP_003002922.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_003002923.1 protein associated with Co2+ and Mg2+ efflux YP_003002924.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_003002925.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_003002926.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_003002927.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_003002928.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_003002929.1 PFAM: pseudouridine synthase; KEGG: eca:ECA3854 ribosomal large subunit pseudouridine synthase A YP_003002930.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_003002931.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_003002932.1 KEGG: eca:ECA4323 hypothetical protein YP_003002935.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA1069 hypothetical protein YP_003002939.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: eli:ELI_07940 putative bacteriophage-acquired protein YP_003002940.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA3850 hypothetical protein YP_003002941.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_003002942.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: eca:ECA3848 acetolactate synthase catalytic subunit YP_003002943.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_003002944.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_003002945.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_003002946.1 activates sgrS under glucose-phosphate stress conditions YP_003002948.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_003002949.1 TIGRFAM: tryptophanase leader peptide YP_003002950.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; Siderophore-interacting protein; KEGG: cko:CKO_00978 hypothetical protein YP_003002951.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003002952.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_003002953.1 TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein; KEGG: yps:YPTB0670 isopropylmalate isomerase large subunit YP_003002954.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_003002955.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_003002956.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA3830 putative AMP-binding protein YP_003002957.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_003002958.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_003002959.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_003002960.1 PFAM: protein of unknown function DUF1144; KEGG: eca:ECA3826 hypothetical protein YP_003002962.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_003002963.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: eca:ECA3823 S-adenosyl-methyltransferase MraW YP_003002964.1 membrane bound cell division protein at septum containing leucine zipper motif YP_003002965.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: eca:ECA3821 peptidoglycan synthetase YP_003002966.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_003002967.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: eca:ECA3819 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_003002968.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_003002969.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_003002970.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_003002971.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_003002972.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_003002974.1 involved in septum formation YP_003002975.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_003002976.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_003002977.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_003002978.1 PFAM: protein of unknown function DUF721; KEGG: eca:ECA3808 hypothetical protein YP_003002979.1 secM translational pause allows for the initiation of secA translation YP_003002980.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_003002981.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: eca:ECA3805 nucleoside triphosphate pyrophosphohydrolase YP_003002982.1 PFAM: protein of unknown function DUF329; KEGG: spe:Spro_0772 hypothetical protein YP_003002983.1 PFAM: protein of unknown function DUF1342; KEGG: eca:ECA3803 hypothetical protein YP_003002984.1 KEGG: eca:ECA3802 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_003002985.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_003002986.1 PFAM: type II secretion system protein; KEGG: eca:ECA3800 type IV pilin biogenesis protein YP_003002987.1 PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: eca:ECA3799 hypothetical protein YP_003002988.1 KEGG: eca:ECA3798 putative major pilin subunit YP_003002989.1 KEGG: eca:ECA3797 quinolinate phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_003002990.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: eca:ECA3796 nucleoside-specific channel-forming protein YP_003002991.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: eca:ECA3795 N-acetyl-anhydromuranmyl-L-alanine amidase YP_003002992.1 involved in regulation of beta-lactamase; putative signaling protein YP_003002993.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA3791 aromatic amino acid transport protein YP_003002994.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_003002995.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_003002996.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_003002997.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: esa:ESA_03220 dihydrolipoamide dehydrogenase YP_003002998.1 PFAM: dienelactone hydrolase; KEGG: eca:ECA3785 hypothetical protein YP_003002999.1 PFAM: MmgE/PrpD family protein; KEGG: eca:ECA3784 hypothetical protein YP_003003000.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_003003001.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3777 hypothetical protein YP_003003002.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: dia:Dtpsy_2395 methyl-accepting chemotaxis sensory transducer YP_003003003.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA3767 short-chain dehydrogenase YP_003003004.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3766 hypothetical protein YP_003003005.1 KEGG: eca:ECA3765 hypothetical protein YP_003003006.1 PFAM: Na+/solute symporter; KEGG: eca:ECA3764 sodium:solute symporter YP_003003007.1 PFAM: dihydrodipicolinate synthetase; KEGG: eca:ECA3763 putative dihydrodipicolinate synthase YP_003003008.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA3762 putative alcohol dehydrogenase YP_003003009.1 PFAM: type III effector Hrp-dependent outers; KEGG: eca:ECA3761 hypothetical protein YP_003003010.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_003003011.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA3759 DeoR family transcriptional regulator YP_003003013.1 PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: bha:BH3836 4-hydroxyphenylacetate-3-hydroxylase YP_003003014.1 PFAM: periplasmic solute binding protein; KEGG: ecp:ECP_3824 putative periplasmic binding protein YP_003003015.1 PFAM: ABC-3 protein; KEGG: ecp:ECP_3823 putative ABC-transporter membrane protein YP_003003016.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ecp:ECP_3822 putative ABC-transporter ATP-binding protein YP_003003018.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: eca:ECA3753 hypothetical protein YP_003003019.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3751 extracellular solute-binding protein YP_003003020.1 KEGG: eca:ECA3750 hypothetical protein YP_003003021.1 PFAM: glycosyl hydrolase family 88; KEGG: eca:ECA3749 plant-inducible protein YP_003003022.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: eca:ECA3748 ABC transporter, ATP-binding protein YP_003003023.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3747 ABC transporter, membrane spanning protein YP_003003024.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3746 ABC transporter, membrane spanning protein YP_003003025.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA3745 LacI family transcriptional regulator YP_003003026.1 KEGG: mgm:Mmc1_0568 DNA replication and repair protein RecF YP_003003027.1 KEGG: stm:PSLT042 putative integrase protein YP_003003028.1 KEGG: mgm:Mmc1_0567 hypothetical protein YP_003003029.1 KEGG: sdn:Sden_2995 hypothetical protein YP_003003030.1 KEGG: ppd:Ppro_0363 hypothetical protein YP_003003031.1 KEGG: sdn:Sden_2998 hypothetical protein YP_003003032.1 KEGG: sdn:Sden_2999 hypothetical protein YP_003003033.1 KEGG: sdn:Sden_3000 hypothetical protein YP_003003034.1 PFAM: GPW/gp25 family protein; KEGG: sdn:Sden_3001 gpW/GP25 YP_003003035.1 PFAM: PAAR repeat-containing protein; KEGG: sdn:Sden_3002 PaaR YP_003003036.1 TIGRFAM: Rhs element Vgr protein; KEGG: sdn:Sden_3003 rhs element Vgr protein YP_003003037.1 PFAM: Peptidoglycan-binding LysM; KEGG: sdn:Sden_3004 hypothetical protein YP_003003039.1 TIGRFAM: conserved hypothetical protein; KEGG: sdn:Sden_3005 hypothetical protein YP_003003040.1 TIGRFAM: conserved hypothetical protein; KEGG: sdn:Sden_3006 hypothetical protein YP_003003041.1 KEGG: sdn:Sden_3007 hypothetical protein YP_003003042.1 KEGG: ppd:Ppro_0374 hypothetical protein YP_003003043.1 KEGG: cja:CJA_3668 hypothetical protein YP_003003044.1 KEGG: yps:YPTB2203 hypothetical protein YP_003003045.1 KEGG: efe:EFER_2439 hypothetical protein YP_003003046.1 KEGG: dac:Daci_3890 hypothetical protein YP_003003047.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: pmy:Pmen_4577 flavin reductase domain-containing protein YP_003003048.1 KEGG: GH16670 gene product from transcript GH16670-RA YP_003003050.1 KEGG: bpt:Bpet4285 mobile mitochondrial group II intron of COX1 which IS involved in pre-mRNA splicing and in deletion of introns from mitochondrial DNA; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); intron maturase type II; SMART: HNH nuclease YP_003003051.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: efe:EFER_4161 single-stranded DNA-binding protein YP_003003052.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_003003053.1 PFAM: protein of unknown function UPF0047; KEGG: eca:ECA3688 hypothetical protein YP_003003054.1 KEGG: eca:ECA3374 putative signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003003055.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0183 methyl-accepting chemotaxis protein YP_003003056.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: eca:ECA3679 hypothetical protein YP_003003057.1 TIGRFAM: CRISPR-associated helicase Cas3 family; KEGG: eca:ECA3680 hypothetical protein YP_003003058.1 TIGRFAM: CRISPR-associated protein, Csy1 family; KEGG: eca:ECA3681 hypothetical protein YP_003003059.1 TIGRFAM: CRISPR-associated protein, Csy2 family; KEGG: eca:ECA3682 hypothetical protein YP_003003060.1 TIGRFAM: CRISPR-associated protein, Csy3 family; KEGG: eca:ECA3683 hypothetical protein YP_003003061.1 TIGRFAM: CRISPR-associated protein, Csy4 family; KEGG: eca:ECA3684 hypothetical protein YP_003003062.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_003003063.1 PFAM: protein of unknown function DUF161; KEGG: eca:ECA3669 hypothetical protein YP_003003064.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: eca:ECA3668 transcription regulator AsnC YP_003003065.1 PFAM: amino acid permease-associated region; KEGG: kpe:KPK_3038 putative aromatic amino acid transport protein AroP YP_003003066.1 KEGG: spe:Spro_4447 arogenate dehydratase; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_003003067.1 PFAM: protein of unknown function DUF1471; KEGG: plu:plu4502 hypothetical protein YP_003003068.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_003003069.1 KEGG: eca:ECA3664 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase YP_003003070.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA3663 quinone oxidoreductase, NADPH-dependent YP_003003071.1 PFAM: cytochrome P450; KEGG: eca:ECA3662 putative cytochrome YP_003003072.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_003003073.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: eca:ECA3660 tRNA-dihydrouridine synthase A YP_003003074.1 KEGG: cja:CJA_3633 hypothetical protein YP_003003075.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_3090 transcriptional regulator, LysR family YP_003003076.1 KEGG: ent:Ent638_2117 hypothetical protein YP_003003077.1 KEGG: ank:AnaeK_3353 hypothetical protein YP_003003078.1 PFAM: major facilitator superfamily MFS_1; KEGG: gbm:Gbem_0782 major facilitator superfamily MFS_1 YP_003003079.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bur:Bcep18194_B2748 LysR family transcriptional regulator YP_003003081.1 PFAM: protein of unknown function DUF1330; KEGG: msu:MS1420 hypothetical protein YP_003003082.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: msu:MS2162 MdaB protein YP_003003083.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: spe:Spro_4489 GntR family transcriptional regulator YP_003003084.1 PFAM: extracellular solute-binding protein family 1; KEGG: spe:Spro_4488 extracellular solute-binding protein YP_003003085.1 KEGG: eta:ETA_31180 hypothetical protein YP_003003086.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_4486 binding-protein-dependent transport systems inner membrane component YP_003003088.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eta:ETA_31160 ABC transporter, permease component, putative fragment YP_003003089.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: spe:Spro_4484 ABC transporter-related protein YP_003003090.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: plu:plu2421 hypothetical protein YP_003003091.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_003003092.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_003003093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: spe:Spro_3834 LacI family transcription regulator YP_003003094.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: eca:ECA3648 PTS system, cellobiose-specific IIA component YP_003003095.1 KEGG: eca:ECA3647 PTS system, lichenan-specific IIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_003003096.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA3646 putative 6-phospho-beta-glucosidase YP_003003097.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: eca:ECA3645 PTS system, lichenan-specific IIB component YP_003003098.1 PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA3644 GntR family transcriptional regulator YP_003003099.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3643 GnaT-family acetyltransferase YP_003003100.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: plu:plu0404 hypothetical protein YP_003003101.1 KEGG: ypy:YPK_2298 hypothetical protein YP_003003102.1 KEGG: rpt:Rpal_4354 hypothetical protein YP_003003103.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: rpb:RPB_3724 filamentation induced by cAMP protein Fic YP_003003104.1 controls transcription of galETKM YP_003003105.1 PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: esa:ESA_02544 hypothetical protein YP_003003106.1 TIGRFAM: PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: esa:ESA_02545 hypothetical protein YP_003003107.1 PFAM: glycoside hydrolase family 1; KEGG: esa:ESA_02546 hypothetical protein YP_003003108.1 PFAM: glycoside hydrolase family 1; KEGG: esa:ESA_02547 hypothetical protein YP_003003109.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_003003110.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3640 hypothetical protein YP_003003111.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3639 putative acyltransferase YP_003003112.1 KEGG: yen:YE1746 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein YP_003003113.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003003114.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_003003115.1 PFAM: protein of unknown function DUF167; KEGG: spe:Spro_4033 hypothetical protein YP_003003116.1 PFAM: protein of unknown function YGGT; KEGG: eca:ECA3629 hypothetical protein YP_003003117.1 KEGG: eca:ECA3628 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_003003118.1 PFAM: alanine racemase domain protein; KEGG: eca:ECA3627 putative alanine racemase YP_003003119.1 KEGG: eca:ECA3626 putative type II/IV secretion system protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_003003120.1 KEGG: sse:Ssed_3337 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein YP_003003121.1 PFAM: Amidohydrolase 3; amidohydrolase; KEGG: bcj:BCAM1457 cytosine deaminase YP_003003122.1 PFAM: helix-turn-helix Fis-type; KEGG: bte:BTH_II1640 DNA-binding protein YP_003003123.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3624 methyl-accepting chemotaxis protein YP_003003124.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_003003125.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_003003126.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_003003127.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0091 methyl-accepting chemotaxis protein YP_003003128.1 KEGG: gsu:GSU0757 putative lipoprotein YP_003003129.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_003003130.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3615 putative methyl-accepting chemotaxis protein YP_003003131.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_003003132.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_003003133.1 binds single-stranded DNA at the primosome assembly site YP_003003134.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_003003135.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_003003136.1 PFAM: protein of unknown function DUF488; KEGG: eca:ECA3609 hypothetical protein YP_003003137.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: eca:ECA3608 hypothetical protein YP_003003138.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_003003139.1 KEGG: spe:Spro_3414 hypothetical protein YP_003003140.1 Involved in anaerobic NO protection and iron metabolism YP_003003141.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_003003142.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_003003143.1 PFAM: protein of unknown function DUF1107; KEGG: eca:ECA3599 hypothetical protein YP_003003144.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA3598 hypothetical protein YP_003003145.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_003003146.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: eca:ECA3596 hypothetical protein YP_003003147.1 PFAM: protein of unknown function DUF490; KEGG: eca:ECA3595 hypothetical protein YP_003003148.1 PFAM: AIG2 family protein; KEGG: plu:plu4552 hypothetical protein YP_003003149.1 PFAM: Inorganic pyrophosphatase; KEGG: spe:Spro_0462 inorganic pyrophosphatase YP_003003150.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3592 methyl-accepting chemotaxis protein YP_003003151.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_003003152.1 KEGG: eca:ECA3590 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; TIGRFAM: dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase YP_003003153.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_003003154.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: eca:ECA3588 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_003003155.1 SMART: SH3 domain protein; KEGG: eca:ECA3587 putative signal transduction protein YP_003003156.1 PFAM: adenylate cyclase; KEGG: eca:ECA3586 hypothetical protein YP_003003157.1 PFAM: glutamate-ammonia ligase adenylyltransferase; GlnD PII-uridylyltransferase; KEGG: eca:ECA3585 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_003003158.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_003003159.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_003003160.1 KEGG: eca:ECA3582 hypothetical protein YP_003003161.1 KEGG: eca:ECA3581 hypothetical protein YP_003003162.1 KEGG: eca:ECA3581 hypothetical protein YP_003003163.1 KEGG: eca:ECA3579 methyl-accepting chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer YP_003003164.1 KEGG: eca:ECA3578 D-galactarate dehydratase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein YP_003003165.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: eca:ECA3577 glucarate transporter YP_003003166.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA3576 glucarate dehydratase YP_003003167.1 KEGG: eca:ECA3575 glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein YP_003003168.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_003003169.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_003003170.1 KEGG: eca:ECA3572 glycerate kinase 2; TIGRFAM: glycerate kinase; PFAM: glycerate kinase YP_003003171.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_003003172.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_003003173.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_003003174.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_003003175.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_003003176.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_003003177.1 KEGG: eca:ECA3560 oligogalacturonide transporter YP_003003178.1 PFAM: glycosyl hydrolase family 88; KEGG: eca:ECA3559 plant-inducible protein YP_003003179.1 PFAM: beta-lactamase domain protein; KEGG: eca:ECA3555 metallo hydrolase YP_003003180.1 KEGG: eca:ECA3554 hypothetical protein YP_003003181.1 TIGRFAM: 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: eca:ECA3553 putative 6-pyruvoyl tetrahydrobiopterin synthase YP_003003182.1 PFAM: glycoside hydrolase family 28; KEGG: eca:ECA3552 putative polygalacturonase YP_003003183.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3551 periplasmic binding protein precursor YP_003003184.1 KEGG: eca:ECA3550 hypothetical protein YP_003003185.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: FAD-binding domain protein; flavodoxin/nitric oxide synthase; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: eca:ECA3547 sulfite reductase subunit alpha YP_003003186.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_003003187.1 TIGRFAM: phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: eca:ECA3545 phosphoadenosine phosphosulfate reductase YP_003003188.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA3544 siroheme synthase [includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase] YP_003003189.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_003003190.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_003003191.1 KEGG: yps:YPTB0767 adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: adenylylsulfate kinase YP_003003192.1 KEGG: eca:ECA3540 hypothetical protein YP_003003193.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_003003194.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: eca:ECA3535 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_003003195.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_003003196.1 catalyzes the modification of U13 in tRNA(Glu) YP_003003197.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_003003198.1 PFAM: Peptidase M23; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: eca:ECA3531 lipoprotein NlpD YP_003003199.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_003003200.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_003003201.1 PFAM: protein of unknown function UPF0066; KEGG: yen:YE3257 hypothetical protein YP_003003202.1 KEGG: eca:ECA3527 outer membrane lipoprotein YP_003003203.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; Substrate-binding region of ABC-type glycine betaine transport system; KEGG: eca:ECA3526 DL-methionine transporter substrate-binding subunit YP_003003204.1 part of the MetNIQ methionine uptake system YP_003003205.1 KEGG: seh:SeHA_C0285 D-methionine ABC transporter, ATP-binding protein; TIGRFAM: D-methionine ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_003003206.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_003003207.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA3522 alpha-ketoglutarate transporter YP_003003208.1 KEGG: eum:ECUMN_2912 conserved hypothetical protein YfiM; putative exported protein YP_003003209.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_003003210.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: eca:ECA3519 putative acyl-CoA synthetase YP_003003211.1 PFAM: DTW domain containing protein; KEGG: eca:ECA3518 hypothetical protein YP_003003212.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: eca:ECA3517 thioredoxin 2 YP_003003214.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: eca:ECA3516 putative methyltransferase YP_003003215.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3513 multidrug resistance protein B YP_003003216.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA3512 multidrug resistance protein A YP_003003217.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_003003218.1 KEGG: eca:ECA3510 hypothetical protein YP_003003219.1 PFAM: AzlC family protein; KEGG: eca:ECA3509 putative amino acid transporter YP_003003220.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3508 putative transport protein YP_003003221.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_003003222.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_003003223.1 KEGG: eca:ECA3502 glycine betaine/L-proline transport ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase YP_003003224.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: kpe:KPK_2569 permease, cytosine/purine, uracil, thiamine, allantoin family YP_003003225.1 PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eta:ETA_26320 transcriptional regulator, GntR family YP_003003226.1 PFAM: Asp/Glu/hydantoin racemase; KEGG: spe:Spro_0915 Asp/Glu racemase YP_003003227.1 KEGG: spe:Spro_0916 chitin deacetylase; TIGRFAM: urate catabolism protein; PFAM: polysaccharide deacetylase YP_003003228.1 PFAM: HipA domain protein; KEGG: spc:Sputcn32_2916 HipA domain-containing protein YP_003003229.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: spe:Spro_3692 putative transcriptional regulator YP_003003230.1 KEGG: eca:ECA3500 hypothetical protein YP_003003231.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_003003232.1 KEGG: eca:ECA3498 hypothetical protein YP_003003233.1 KEGG: eca:ECA3497 putative gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_003003234.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: eca:ECA3496 putative transcriptional regulator YP_003003235.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA3495 putative amino acid ABC transporter, substrate binding protein YP_003003236.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3494 putative amino acid ABC transporter, permease protein YP_003003237.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3493 putative amino acid ABC transporter, permease protein YP_003003238.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3492 putative amino acid ABC transporter, ATP-binding protein YP_003003239.1 PFAM: aminotransferase class V; KEGG: eca:ECA3491 purine catabolism protein YP_003003240.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_003003241.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eca:ECA3489 hypothetical protein YP_003003242.1 catalyzes the transfer of an amino moiety YP_003003243.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_003003244.1 KEGG: eca:ECA3486 enolase-phosphatase; TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase YP_003003245.1 PFAM: Acireductone dioxygenase ARD; KEGG: eca:ECA3485 oxidase YP_003003246.1 KEGG: eca:ECA3477 putative translation initiation factor EIF-2B; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_003003247.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_003003248.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_003003249.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_003003250.1 PFAM: glutamine amidotransferase class-II; KEGG: eca:ECA3472 hypothetical protein YP_003003251.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA3471 hypothetical protein YP_003003252.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_003003253.1 KEGG: yen:YE3206 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20 YP_003003255.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_003003256.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_003003257.1 PFAM: transcriptional regulator Crl; KEGG: cko:CKO_02956 DNA-binding transcriptional regulator Crl YP_003003258.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_003003259.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_003003260.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA0964 putative regulatory protein YP_003003261.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA0964 putative regulatory protein YP_003003262.1 KEGG: eca:ECA0513 putative phage transcriptional regulator YP_003003263.1 TIGRFAM: CRISPR-associated protein Cas2; KEGG: vco:VC0395_A2677 CRISPR-associated protein Cas2 YP_003003264.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: vco:VC0395_A2676 CRISPR-associated protein Cas1 YP_003003265.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: vco:VC0395_A2675 CRISPR-associated protein Cas5, ecoli subtype YP_003003266.1 TIGRFAM: CRISPR-associated protein, Cse4 family; KEGG: vco:VC0395_A2674 CRISPR-associated protein, CSE4 family YP_003003267.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: vco:VC0395_A2673 CRISPR-associated protein, CSE3 family YP_003003268.1 TIGRFAM: CRISPR-associated protein, Cse2 family; KEGG: vco:VC0395_A2672 CRISPR-associated protein, CSE2 family YP_003003269.1 TIGRFAM: CRISPR-associated protein, Cse1 family; KEGG: vco:VC0395_A2671 CRISPR-associated protein, CSE1 family YP_003003270.1 KEGG: vco:VC0395_A2670 CRISPR-associated helicase Cas3 domain protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein YP_003003271.1 KEGG: cja:CJA_2458 hypothetical protein YP_003003272.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bps:BPSL0756 putative DNA-binding protein YP_003003273.1 KEGG: nmu:Nmul_A1533 hypothetical protein YP_003003274.1 PFAM: replication gene A; KEGG: spe:Spro_0874 replication gene A YP_003003275.1 KEGG: sbn:Sbal195_3111 hypothetical protein YP_003003276.1 KEGG: sat:SYN_02230 putative cytoplasmic protein YP_003003277.1 PFAM: integrase family protein; KEGG: psa:PST_1489 integrase YP_003003278.1 KEGG: ypi:YpsIP31758_0549 HNH endonuclease domain-containing protein YP_003003279.1 PFAM: Prophage CP4-57 regulatory; KEGG: ypy:YPK_3752 phage transcriptional regulator, AlpA YP_003003280.1 KEGG: ecd:ECDH10B_2791 CP4-57 prophage; hypothetical protein YP_003003281.1 KEGG: ecd:ECDH10B_2792 CP4-57 prophage; hypothetical protein YP_003003282.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: rpi:Rpic_0450 type I restriction-modification system, M subunit YP_003003285.1 KEGG: rpi:Rpic_0447 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicase YP_003003286.1 PFAM: GTP-binding protein HSR1-related; KEGG: ecd:ECDH10B_0238 CP4-6 prophage; GTP-binding protein YP_003003287.1 PFAM: protein of unknown function DUF932; KEGG: ecd:ECDH10B_0237 CP4-6 prophage; hypothetical protein YP_003003288.1 TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: ent:Ent638_0474 DNA repair protein RadC YP_003003289.1 PFAM: protein of unknown function DUF1219; KEGG: eca:ECA2853 hypothetical protein YP_003003290.1 KEGG: spc:Sputcn32_3528 hypothetical protein YP_003003291.1 PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: neu:NE1364 Appr-1-p processing enzyme YP_003003293.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: psp:PSPPH_2193 LysR family transcriptional regulator YP_003003294.1 PFAM: protein of unknown function UPF0074; KEGG: pst:PSPTO_2406 hypothetical protein YP_003003295.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pst:PSPTO_2407 hypothetical protein YP_003003296.1 PFAM: Pirin domain protein; KEGG: psp:PSPPH_2192 pirin YP_003003297.1 PFAM: Insertion element protein; KEGG: sdy:SDY_P213 iso-IS1 ORF1 YP_003003298.1 KEGG: eca:ECA2042 hypothetical protein YP_003003299.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: pmr:PMI0007 hypothetical protein YP_003003300.1 KEGG: aha:AHA_1993 ada regulatory protein; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type YP_003003301.1 KEGG: eca:ECA3130 poly(glycerophosphate chain) D-alanine transfer protein YP_003003303.1 PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: eca:ECA3129 peptidoglycan biosynthesis protein YP_003003304.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA3128 putative D-alanine--poly(phosphoribitol) ligase subunit 1 YP_003003305.1 KEGG: eca:ECA3127 acyl carrier protein YP_003003306.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bch:Bcen2424_6323 AraC family transcriptional regulator YP_003003307.1 KEGG: bcm:Bcenmc03_1718 hypothetical protein YP_003003308.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: bch:Bcen2424_3293 (acyl-carrier-protein) phosphodiesterase YP_003003309.1 PFAM: YCII-related; KEGG: ent:Ent638_0388 hypothetical protein YP_003003310.1 KEGG: efe:EFER_2212 sensory kinase in two-component system with YehT; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: GAF domain protein YP_003003311.1 unknown function; when overproduced it confers drug-resistance YP_003003312.1 PFAM: carbon starvation protein CstA; KEGG: eum:ECUMN_4963 conserved hypothetical protein; putative inner membrane protein YP_003003313.1 PFAM: protein of unknown function DUF466; KEGG: eca:ECA1188 hypothetical protein YP_003003314.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sbc:SbBS512_E4878 CobW/P47K family protein YP_003003315.1 activates the transcription of the ethanolamine utilization operon YP_003003316.1 PFAM: Aldehyde Dehydrogenase; KEGG: ecz:ECS88_2634 putative aldehyde dehydrogenase, ethanolamine utilization protein YP_003003317.1 PFAM: peptidase U34 dipeptidase; KEGG: dal:Dalk_1471 peptidase U34 dipeptidase YP_003003318.1 PFAM: phosphatidylserine decarboxylase-related; KEGG: bxe:Bxe_C0076 putative phosphatidylserine decarboxylase YP_003003319.1 membrane component of a putative sugar ABC transporter system YP_003003320.1 PFAM: inner-membrane translocator; KEGG: kpe:KPK_5041 putative sugar ABC transporter, permease protein YP_003003321.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_0413 ABC transporter related YP_003003322.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: kpe:KPK_5043 putative sugar ABC transporter, periplasmic sugar-binding protein YP_003003324.1 SMART: Ankyrin; KEGG: pap:PSPA7_5252 hypothetical protein YP_003003325.1 PFAM: Catalase domain protein; KEGG: pau:PA14_61040 catalase YP_003003326.1 TIGRFAM: acetoin reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpe:KPK_2269 acetoin dehydrogenase YP_003003328.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eta:ETA_25920 lysine exporter protein (LysE/YggA) YP_003003329.1 PFAM: cytochrome B561; KEGG: esa:ESA_01704 hypothetical protein YP_003003330.1 PFAM: cyclase/dehydrase; KEGG: eca:ECA3372 hypothetical protein YP_003003331.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bte:BTH_II0494 acetyltransferase YP_003003332.1 PFAM: CinA domain protein; KEGG: eca:ECA3370 competence damage-inducible protein A YP_003003333.1 KEGG: eca:ECA3369 recombinase A; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: AAA ATPase YP_003003334.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_003003335.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003003336.1 affects carbohydrate metabolism; has regulatory role in many processes YP_003003337.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_003003338.1 KEGG: eca:ECA3364 hypothetical protein YP_003003339.1 involved in the first step of glutathione biosynthesis YP_003003340.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_003003341.1 PFAM: cytochrome c assembly protein; KEGG: eca:ECA3361 hypothetical protein YP_003003342.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_003003343.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_003003344.1 Essential for efficient processing of 16S rRNA YP_003003345.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_003003346.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_003003347.1 KEGG: eca:ECA3355 hypothetical protein YP_003003348.1 KEGG: eca:ECA3354 hypothetical protein YP_003003349.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_003003350.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_003003351.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_003003352.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: eca:ECA3349 putative sigma(54) modulation protein YP_003003353.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_003003354.1 KEGG: eca:ECA3347 23S rRNA pseudouridine synthase D; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein YP_003003355.1 PFAM: protein of unknown function DUF152; KEGG: eca:ECA3346 hypothetical protein YP_003003356.1 KEGG: eca:ECA3345 protein disaggregation chaperone; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase YP_003003357.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: eca:ECA3344 hypothetical protein YP_003003358.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_003003359.1 KEGG: eca:ECA3342 hydroxyacylglutathione hydrolase; TIGRFAM: hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein YP_003003360.1 PFAM: Methyltransferase type 11; KEGG: spe:Spro_0910 methyltransferase type 11 YP_003003361.1 PFAM: ribonuclease H; KEGG: ypi:YpsIP31758_1054 ribonuclease H YP_003003362.1 3'-5' exonuclease of DNA polymerase III YP_003003363.1 PFAM: ribonucleotide reductase; KEGG: eca:ECA3338 ribonucleotide-diphosphate reductase subunit beta YP_003003364.1 KEGG: ypp:YPDSF_1623 ribonucleotide-diphosphate reductase subunit alpha; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase domain protein; Ribonucleotide reductase large subunit domain protein YP_003003365.1 TIGRFAM: NrdI protein; PFAM: NrdI family protein; KEGG: eca:ECA3336 ribonucleotide reductase stimulatory protein YP_003003366.1 PFAM: glutaredoxin; KEGG: eca:ECA3335 putative glutaredoxin YP_003003367.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_003003368.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_003003369.1 KEGG: eca:ECA3332 hypothetical protein YP_003003370.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3331 ABC transporter, permease protein YP_003003371.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: eca:ECA3330 ATP transporter ATP-binding protein YP_003003372.1 KEGG: asa:ASA_3604 hypothetical protein YP_003003373.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3329 putative acetyltransferase YP_003003374.1 KEGG: eca:ECA3328 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_003003375.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_003003376.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_3996 ABC transporter-related protein YP_003003377.1 PFAM: ABC-2 type transporter; KEGG: eca:ECA3324 ABC transporter integral membrane protein YP_003003378.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_003003379.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_003003380.1 KEGG: eca:ECA3321 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase YP_003003381.1 KEGG: eca:ECA3320 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_003003382.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: eca:ECA3318 glutamyl-Q tRNA(Asp) synthetase YP_003003383.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: efe:EFER_0168 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein YP_003003384.1 TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; KEGG: eca:ECA3316 sugar fermentation stimulation protein A YP_003003385.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: eca:ECA3315 2'-5' RNA ligase YP_003003386.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_003003387.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_003003388.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_003003389.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: spe:Spro_0783 iron-sulfur cluster assembly accessory protein YP_003003390.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3304 vitamin B12-transporter protein BtuF YP_003003391.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_003003392.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_003003393.1 protease Do; required at high temperature; degrades damaged proteins YP_003003394.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_003003395.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3299 sulfate-binding protein YP_003003396.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit CysT; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3298 sulfate ABC transporter permease protein YP_003003397.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit CysW; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3297 sulfate ABC transporter permease protein YP_003003398.1 KEGG: eca:ECA3296 sulphate ABC transporter ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_003003399.1 KEGG: baa:BA_0301 phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_003003400.1 PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; KEGG: hypothetical protein YP_003003401.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: swp:swp_2451 transcriptional regulator, AraC family YP_003003402.1 KEGG: asa:ASA_2994 sucrose porin YP_003003403.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ccv:CCV52592_0665 alpha/beta hydrolase domain-containing protein YP_003003404.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: spe:Spro_4224 phosphotransferase system lactose/cellobiose-specific IIB subunit YP_003003405.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: vsa:VSAL_I0707 phosphotransferase system (PTS) component IIA YP_003003406.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_003003407.1 KEGG: pfl:PFL_0498 O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; DegT/DnrJ/EryC1/StrS aminotransferase YP_003003408.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_003003409.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_003003410.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_003003411.1 PFAM: methyltransferase small; KEGG: eca:ECA3286 hypothetical protein YP_003003412.1 TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: eca:ECA3285 L-aspartate oxidase YP_003003413.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_003003414.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: spe:Spro_3675 anti-RNA polymerase sigma factor SigE YP_003003415.1 PFAM: MucB/RseB family protein; KEGG: spe:Spro_3674 periplasmic negative regulator of sigmaE YP_003003416.1 involved in the reduction of the SoxR iron-sulfur cluster YP_003003417.1 TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; PFAM: GTP-binding protein LepA domain protein; elongation factor G domain protein; elongation factor Tu domain 2 protein; protein synthesis factor GTP-binding; KEGG: eca:ECA3280 GTP-binding protein LepA YP_003003418.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_003003419.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_003003420.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_003003421.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O RecO; KEGG: eca:ECA3276 DNA repair protein RecO YP_003003422.1 KEGG: eca:ECA3275 pyridoxal phosphate biosynthetic protein PdxJ; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ YP_003003423.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_003003424.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: esa:ESA_00697 hypothetical protein YP_003003425.1 in Escherichia coli this protein is involved in flagellar function YP_003003426.1 KEGG: eca:ECA3270 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein YP_003003427.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: eca:ECA3269 HlyD family secretion protein YP_003003428.1 KEGG: eca:ECA3268 putative toxin secretion ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase YP_003003429.1 KEGG: eca:ECA3265 hypothetical protein YP_003003430.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_003003431.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: eca:ECA3260 tRNA-specific adenosine deaminase YP_003003432.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_003003433.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_003003434.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA3257 two-component system sensor kinase YP_003003435.1 KEGG: eca:ECA3256 hypothetical protein YP_003003436.1 PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: eca:ECA3255 two-component system response regulator YP_003003437.1 PFAM: nitrogen regulatory protein P-II; KEGG: eca:ECA3254 nitrogen regulatory protein P-II 1 YP_003003438.1 PFAM: Pectinesterase; KEGG: eca:ECA3253 pectinesterase A YP_003003439.1 KEGG: eca:ECA3252 pectin acetylesterase YP_003003440.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: xcb:XC_3590 pectate lyase YP_003003441.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: xca:xccb100_3711 exported pectate lyase YP_003003442.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: xcc:XCC0645 pectate lyase YP_003003443.1 PFAM: globin; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: eca:ECA3251 nitric oxide dioxygenase YP_003003444.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_003003445.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_003003446.1 PFAM: protein of unknown function DUF1007; KEGG: eca:ECA3248 hypothetical protein YP_003003447.1 PFAM: high-affinity nickel-transporter; KEGG: eca:ECA3247 hypothetical protein YP_003003448.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3246 putative periplasmic substrate-binding transport protein YP_003003449.1 PFAM: ABC transporter related; SMC domain protein; SMART: AAA ATPase; KEGG: eca:ECA3243 putative ferric-enterobactin ABC transporter ATP-binding protein YP_003003450.1 PFAM: transport system permease protein; KEGG: eca:ECA3242 ABC transporter permease YP_003003451.1 KEGG: eca:ECA3241 ABC transporter, substrate binding protein YP_003003452.1 PFAM: inositol monophosphatase; KEGG: eca:ECA3240 inositol monophosphatase YP_003003453.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: eca:ECA3239 putative RNA methyltransferase YP_003003454.1 regulates the expression of the iscRSUA operon YP_003003455.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_003003456.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: eca:ECA3236 scaffold protein YP_003003457.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_003003458.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_003003459.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_003003460.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: cko:CKO_00256 hypothetical protein YP_003003461.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: stm:STM2537 hypothetical protein YP_003003462.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_003003463.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_003003464.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_003003465.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_003003466.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_003003467.1 KEGG: eca:ECA3222 hypothetical protein; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_003003468.1 SMART: helix-turn-helix domain protein; KEGG: eca:ECA3221 hypothetical protein YP_003003469.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_003003470.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_003003471.1 KEGG: eca:ECA3218 hypothetical protein YP_003003472.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_003003473.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_003003474.1 PFAM: protein of unknown function DUF1407; KEGG: spe:Spro_3603 hypothetical protein YP_003003475.1 KEGG: eca:ECA3212 hypothetical protein YP_003003476.1 PFAM: peptidase M4 thermolysin; Peptidase M4 thermolysin; KEGG: eca:ECA3211 extracellular metalloprotease YP_003003477.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_003003478.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_003003479.1 TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; KEGG: eca:ECA3208 bifunctional GMP synthase/glutamine amidotransferase protein YP_003003481.1 PFAM: integrase family protein; KEGG: bam:Bamb_2021 phage integrase family protein YP_003003482.1 KEGG: dia:Dtpsy_1263 hypothetical protein YP_003003483.1 PFAM: Prophage CP4-57 regulatory; KEGG: rme:Rmet_1467 prophage CP4-57 regulatory YP_003003484.1 PFAM: Prophage CP4-57 regulatory; KEGG: rme:Rmet_1468 phage transcriptional regulator, AlpA YP_003003485.1 TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: shn:Shewana3_1252 DNA repair protein RadC YP_003003486.1 PFAM: protein of unknown function DUF736; KEGG: pna:Pnap_4161 hypothetical protein YP_003003487.1 KEGG: bvi:Bcep1808_0258 hypothetical protein YP_003003488.1 KEGG: reu:Reut_A2939 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; SMART: metal-dependent phosphohydrolase HD region YP_003003489.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: spl:Spea_4213 transposase IS116/IS110/IS902 family protein YP_003003490.1 KEGG: bmj:BMULJ_00913 hypothetical protein YP_003003491.1 KEGG: pna:Pnap_4165 hypothetical protein YP_003003492.1 KEGG: pna:Pnap_4166 putative replication initiator and transcription repressor protein YP_003003493.1 TIGRFAM: P-type conjugative transfer protein TrbJ; KEGG: aav:Aave_0730 putative conjugal transfer TrbJ signal peptide protein YP_003003494.1 TIGRFAM: P-type conjugative transfer protein TrbL; PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: dac:Daci_2693 P-type conjugative transfer protein TrbL YP_003003495.1 PFAM: Conjugal transfer protein; KEGG: shn:Shewana3_1289 conjugal transfer protein YP_003003496.1 TIGRFAM: P-type conjugative transfer protein TrbG; PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: pau:PA14_30860 TrbG-like protein YP_003003497.1 PFAM: conjugation TrbI family protein; KEGG: shn:Shewana3_1291 conjugation TrbI family protein YP_003003498.1 PFAM: plasmid stabilization system; KEGG: rle:pRL110045 hypothetical protein YP_003003499.1 KEGG: vch:VCA0504 RelB protein YP_003003500.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns YP_003003501.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu4299 hypothetical protein YP_003003502.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu4299 hypothetical protein YP_003003503.1 KEGG: eca:ECA0513 putative phage transcriptional regulator YP_003003504.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA3392 hypothetical protein YP_003003505.1 KEGG: msu:MS0414 hypothetical protein YP_003003506.1 TIGRFAM: YD repeat protein; PFAM: PAAR repeat-containing protein; YD repeat-containing protein; KEGG: eca:ECA4278 rhs-family protein YP_003003507.1 PFAM: Domain of unknown function DUF1795; KEGG: eca:ECA2868 hypothetical protein YP_003003508.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 putative rhs accessory genetic element YP_003003509.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA2866 hypothetical protein YP_003003512.1 PFAM: regulatory protein TetR; KEGG: ara:Arad_0508 transcriptional regulator protein YP_003003514.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pfo:Pfl01_3057 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_003003515.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: pfo:Pfl01_3056 antibiotic biosynthesis monooxygenase YP_003003516.1 KEGG: eta:ETA_05100 hypothetical protein YP_003003517.1 PFAM: helix-turn-helix HxlR type; transcriptional regulator PadR family protein; KEGG: xca:xccb100_2343 putative HTH-type transcriptional regulator YP_003003518.1 PFAM: NmrA family protein; KEGG: xca:xccb100_2338 hypothetical protein YP_003003519.1 PFAM: carbonic anhydrase; KEGG: spe:Spro_0566 carbonate dehydratase YP_003003520.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: stt:t1257 putative pathogenicity island protein YP_003003521.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: kpe:KPK_4915 cyclopropane-fatty-acyl-phospholipid synthase family protein YP_003003522.1 PFAM: protein of unknown function DUF1365; KEGG: ent:Ent638_1488 hypothetical protein YP_003003523.1 PFAM: FAD dependent oxidoreductase; KEGG: ent:Ent638_1489 amine oxidase YP_003003524.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: ent:Ent638_1490 short-chain dehydrogenase/reductase SDR YP_003003525.1 KEGG: kpe:KPK_4911 hypothetical protein YP_003003526.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: ent:Ent638_0064 MerR family transcriptional regulator YP_003003527.1 KEGG: eca:ECA3203 hypothetical protein YP_003003528.1 PFAM: protein of unknown function DUF969; KEGG: esa:ESA_02631 hypothetical protein YP_003003529.1 PFAM: protein of unknown function DUF979; KEGG: esa:ESA_02630 hypothetical protein YP_003003530.1 KEGG: esa:ESA_02629 hypothetical protein YP_003003531.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA3501 hypothetical protein YP_003003532.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sec:SC1631 putative ABC-type transport system membrane spanning protein YP_003003533.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: see:SNSL254_A1751 ABC transporter ATP-binding subunit YP_003003534.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sea:SeAg_B1523 putative ABC transporter permease component YP_003003535.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: stt:t1536 putative periplasmic amino acid-binding protein YP_003003536.1 KEGG: eca:ECA3197 hydroxyethylthiazole kinase; TIGRFAM: hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase YP_003003537.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_003003538.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: eca:ECA1396 hypothetical protein YP_003003539.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: eca:ECA1397 LacI family transcriptional regulator YP_003003540.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; Oxidoreductase domain; KEGG: eca:ECA1398 putativeoxidoreductase YP_003003541.1 PFAM: Xylose isomerase domain protein TIM barrel; AP endonuclease 2 domain protein; KEGG: eca:ECA1399 hypothetical protein YP_003003542.1 PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: eca:ECA1400 putative nucleoside H+ symporter YP_003003543.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: spe:Spro_2394 xylose isomerase domain-containing protein YP_003003544.1 PFAM: phosphate-starvation-inducible E; KEGG: eca:ECA3195 phosphate-starvation-inducible protein PsiE YP_003003545.1 PFAM: peptidase U32; KEGG: eca:ECA3193 putative protease YP_003003546.1 KEGG: eca:ECA3192 hypothetical protein YP_003003547.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_003003548.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA3188 signal transduction histidine-protein kinase BaeS YP_003003549.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3187 multidrug efflux system protein MdtE YP_003003550.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_003003551.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_003003552.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_003003553.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: spe:Spro_3416 nucleoside transporter YP_003003554.1 PFAM: aldo/keto reductase; KEGG: eca:ECA3182 oxidoreductase YP_003003555.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_003003556.1 PFAM: cell division inhibitor SulA; KEGG: eca:ECA1752 SOS cell division inhibitor YP_003003557.1 PFAM: TfoX domain protein; KEGG: eca:ECA1753 hypothetical protein YP_003003558.1 TIGRFAM: hypothetical protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: eca:ECA1754 hypothetical protein YP_003003559.1 PFAM: protein of unknown function DUF307; KEGG: efe:EFER_1098 conserved hypothetical protein; putative inner membrane protein YP_003003560.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_003003561.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_003003562.1 KEGG: spe:Spro_1761 hypothetical protein YP_003003563.1 PFAM: CoA-binding domain protein; KEGG: eca:ECA1759 putative CoA binding protein YP_003003564.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: eca:ECA1760 hypothetical protein YP_003003565.1 PFAM: acylphosphatase; KEGG: eca:ECA1761 putative acylphosphatase YP_003003566.1 TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; KEGG: ypb:YPTS_1571 TusE/DsrC/DsvC family sulfur relay protein YP_003003567.1 PFAM: protein of unknown function UPF0005; KEGG: eca:ECA1763 hypothetical protein YP_003003570.1 KEGG: plu:plu4519 IS427 family transposase YP_003003571.1 PFAM: acyltransferase 3; KEGG: bam:Bamb_3866 acyltransferase 3 YP_003003573.1 PFAM: transposase IS3/IS911 family protein; KEGG: eci:UTI89_C4918 hypothetical protein YP_003003574.1 PFAM: isochorismatase hydrolase; KEGG: eca:ECA1767 isochorismatase family protein YP_003003575.1 KEGG: ent:Ent638_2008 putative cytoplasmic protein YP_003003576.1 PFAM: UspA domain protein; KEGG: eca:ECA1769 hypothetical protein YP_003003577.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: pmr:PMI2410 zinc-finger YP_003003578.1 PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase YP_003003579.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_003003580.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3163 phosphate ABC transporter permease protein YP_003003581.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3162 phosphate ABC transporter permease protein YP_003003582.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_003003583.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3160 putative transcriptional regulator YP_003003584.1 KEGG: eca:ECA3159 L-serine dehydratase 2; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_003003585.1 TIGRFAM: serine transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: eca:ECA3158 serine transporter YP_003003586.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_003003587.1 KEGG: eca:ECA3156 phosphoribosylaminoimidazole carboxylase catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_003003588.1 TIGRFAM: UDP-2,3-diacylglucosamine hydrolase; PFAM: metallophosphoesterase; KEGG: spe:Spro_1164 UDP-2,3-diacylglucosamine hydrolase YP_003003589.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: yen:YE3049 peptidyl-prolyl cis-trans isomerase B (rotamase B) YP_003003590.1 PFAM: DoxX family protein; KEGG: eca:ECA3152 hypothetical protein YP_003003591.1 KEGG: eca:ECA3151 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia ; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M) YP_003003592.1 KEGG: eca:ECA3150 hypothetical protein YP_003003593.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_003003594.1 PFAM: Nitrate and nitrite sensing domain protein; chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA0434 methyl-accepting chemotaxis protein YP_003003595.1 TIGRFAM: N-formylglutamate amidohydrolase; PFAM: N-formylglutamate amidohydrolase; KEGG: spe:Spro_2076 N-formylglutamate amidohydrolase YP_003003596.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_003003597.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_003003598.1 PFAM: protein of unknown function DUF886; KEGG: kpn:KPN_01285 hypothetical protein YP_003003599.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: kpe:KPK_3146 amino acid ABC transporter, periplasmic amino acid-binding protein YP_003003600.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpe:KPK_3145 amino acid ABC transporter, permease protein YP_003003601.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpe:KPK_3144 amino acid ABC transporter, permease protein YP_003003602.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpe:KPK_3143 amino acid ABC transporter, ATP-binding protein YP_003003603.1 KEGG: kpe:KPK_3142 putative histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase YP_003003604.1 KEGG: yen:YE2460 GntR family transcriptional regulator; TIGRFAM: histidine utilization repressor; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH YP_003003605.1 PFAM: protein of unknown function UPF0153; KEGG: pfo:Pfl01_4657 hypothetical protein YP_003003606.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_003003607.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_003003608.1 PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0921 GntR family transcriptional regulator YP_003003609.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0920 carbohydrate oxidoreductase YP_003003610.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: eca:ECA0919 transport protein YP_003003611.1 PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: eca:ECA0918 putative dehydrogenase YP_003003612.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: spe:Spro_3563 mandelate racemase/muconate lactonizing protein YP_003003614.1 KEGG: sme:SMc02038 glycerol dehydrogenase YP_003003615.1 PFAM: Pectate lyase; KEGG: eca:ECA1094 pectate lyase YP_003003616.1 KEGG: asa:ASA_3538 hypothetical protein YP_003003617.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ypb:YPTS_3224 ABC transporter related YP_003003618.1 PFAM: extracellular solute-binding protein family 1; KEGG: kpe:KPK_4253 sugar ABC transporter, periplasmic sugar-binding protein YP_003003619.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpe:KPK_4252 sugar ABC transporter, permease protein YP_003003620.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypg:YpAngola_A3885 ABC maltose/maltodextrin transporter, permease subunit YP_003003621.1 PFAM: glycosyl hydrolase 53 domain protein; KEGG: ypg:YpAngola_A3886 glycosy hydrolase family protein YP_003003622.1 PFAM: Glycoside hydrolase family 42 domain protein; Beta-galactosidase trimerisation domain protein; Beta-galactosidase domain protein; KEGG: esa:ESA_03417 hypothetical protein YP_003003623.1 PFAM: phosphotransferase system PTS EIIB protein; KEGG: kpn:KPN_00432 putative phosphotransferase system PTS YP_003003624.1 porin involved in the transport of maltose and maltodextrins YP_003003625.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_003003626.1 KEGG: eca:ECA3166 hypothetical protein YP_003003627.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: yen:YE3022 hypothetical protein YP_003003628.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: yen:YE3423 transcription regulator ArsR YP_003003629.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mms:mma_0767 LysR family transcriptional regulator YP_003003630.1 KEGG: eca:ECA0249 hypothetical protein YP_003003631.1 PFAM: aldo/keto reductase; KEGG: eca:ECA0250 putative oxidoreductase YP_003003632.1 KEGG: eca:ECA2840 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003003633.1 KEGG: bja:bll2387 hypothetical protein YP_003003635.1 PFAM: MscS Mechanosensitive ion channel; KEGG: eca:ECA3118 putative mechanosensitive ion channel protein YP_003003636.1 PFAM: aminotransferase class IV; KEGG: eca:ECA3117 D-alanine aminotransferase YP_003003637.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA3115 aminotransferase YP_003003638.1 TIGRFAM: lipoprotein, PulS/OutS family; KEGG: eca:ECA3114 general secretion pathway lipoprotein YP_003003639.1 KEGG: eca:ECA3113 general secretion pathway protein YP_003003640.1 TIGRFAM: general secretion pathway protein C; KEGG: eca:ECA3110 general secretion pathway protein C YP_003003641.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: kpn:KPN_00160 pullulanase D protein YP_003003642.1 KEGG: eca:ECA3108 general secretion pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_003003643.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: eca:ECA3107 general secretion pathway protein F YP_003003644.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: eca:ECA3106 general secretion pathway protein G YP_003003645.1 TIGRFAM: general secretion pathway protein H; KEGG: eca:ECA3105 general secretion pathway protein H YP_003003646.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: eca:ECA3104 general secretion pathway protein I YP_003003647.1 TIGRFAM: general secretion pathway protein J; KEGG: eca:ECA3103 general secretion pathway protein J YP_003003648.1 PFAM: General secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K YP_003003649.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: eca:ECA3101 general secretion pathway protein L YP_003003650.1 PFAM: General secretion pathway M protein; KEGG: eca:ECA3100 general secretion pathway protein M YP_003003651.1 PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: eca:ECA3098 type 4 prepilin-like proteins leader peptide processing enzyme YP_003003653.1 PFAM: protein of unknown function DUF1234; KEGG: eca:ECA3091 hypothetical protein YP_003003654.1 KEGG: eca:ECA3326 hypothetical protein YP_003003655.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: esa:ESA_01712 hypothetical protein YP_003003656.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA1857 hypothetical protein YP_003003657.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_003003658.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: spe:Spro_3419 isochorismatase YP_003003659.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_003003660.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: spe:Spro_3421 isochorismate synthase YP_003003661.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ent:Ent638_1079 TonB-dependent siderophore receptor YP_003003662.1 PFAM: putative esterase; KEGG: yen:YE3622 enterobactin/ferric enterobactin esterase YP_003003663.1 PFAM: MbtH domain protein; KEGG: cvi:CV_2232 MbtH-like protein YP_003003664.1 TIGRFAM: amino acid adenylation domain protein; non-ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: cvi:CV_2233 synthetase CbsF YP_003003666.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3621 iron-siderophore transport system, ATP-binding component YP_003003667.1 PFAM: transport system permease protein; KEGG: yen:YE3620 iron-enterobactin transporter permease YP_003003668.1 PFAM: transport system permease protein; KEGG: yen:YE3619 iron-enterobactin transporter membrane protein YP_003003669.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_003003670.1 with FepCDG is involved in the transport of ferric enterobactin YP_003003672.1 KEGG: eca:ECA0931 putative avirulence protein YP_003003673.1 KEGG: eca:ECA0931 putative avirulence protein YP_003003674.1 TIGRFAM: 5'-nucleotidase, lipoprotein e(P4) family; PFAM: acid phosphatase (Class B); KEGG: spe:Spro_1456 5'-nucleotidase YP_003003675.1 PFAM: Necrosis inducing; KEGG: eca:ECA3087 hypothetical protein YP_003003676.1 KEGG: sfl:SF1773 putative acetyltransferase YP_003003677.1 PFAM: VacJ family lipoprotein; KEGG: eca:ECA3083 lipoprotein YP_003003678.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_003003679.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: eca:ECA3081 long-chain fatty acid outer membrane transporter YP_003003680.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3080 hypothetical protein YP_003003681.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_003003682.1 TIGRFAM: fatty acid oxidation complex, alpha subunit FadJ; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3078 multifunctional fatty acid oxidation complex subunit alpha YP_003003683.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: eca:ECA3072 phosphohistidine phosphatase YP_003003684.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: eca:ECA3071 hypothetical protein YP_003003685.1 KEGG: yen:YE1280 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small YP_003003686.1 KEGG: eca:ECA3069 chorismate synthase; TIGRFAM: chorismate synthase; PFAM: chorismate synthase YP_003003687.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_003003688.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA3067 hypothetical protein YP_003003689.1 PFAM: protein of unknown function DUF462; KEGG: stm:STM2381 putative cytoplasmic protein YP_003003690.1 PFAM: YfcL protein; KEGG: eca:ECA3065 hypothetical protein YP_003003691.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: eca:ECA3561 LysR family transcriptional regulator YP_003003692.1 PFAM: Aldehyde Dehydrogenase; KEGG: eca:ECA3562 coniferyl aldehyde dehydrogenase YP_003003693.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA3563 hypothetical protein YP_003003694.1 PFAM: Glutathione S-transferase domain; KEGG: eca:ECA1072 glutathione S-transferase YP_003003695.1 PFAM: OsmC family protein; KEGG: bav:BAV2446 organic hydroperoxide resistance protein YP_003003696.1 PFAM: branched-chain amino acid transport; KEGG: cvi:CV_0704 hypothetical protein YP_003003697.1 PFAM: AzlC family protein; KEGG: bxe:Bxe_B2443 branched-chain amino acid exporter, LIV-E family YP_003003698.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bxe:Bxe_B2442 AraC family transcriptional regulator YP_003003699.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_003003700.1 PFAM: Beta-ketoacyl synthase; KEGG: kpn:KPN_02713 3-oxoacyl-(acyl carrier protein) synthase I YP_003003701.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_003003702.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: cko:CKO_04003 hypothetical protein YP_003003703.1 KEGG: spe:Spro_3343 tricarboxylic transport YP_003003704.1 PFAM: conserved hypothetical protein; KEGG: stm:STM2786 tricarboxylic transport YP_003003705.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: spe:Spro_3340 two component transcriptional regulator YP_003003706.1 PFAM: Two-component sensor kinase domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: spe:Spro_3339 integral membrane sensor signal transduction histidine kinase YP_003003707.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: esa:ESA_00896 hypothetical protein YP_003003708.1 PFAM: Semialdehyde dehydrogenase dimerisation region; Semialdehyde dehydrogenase NAD - binding; KEGG: eca:ECA3059 putative semialdehyde dehydrogenase YP_003003709.1 KEGG: eca:ECA3058 tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase YP_003003710.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA3057 hypothetical protein YP_003003711.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_003003712.1 KEGG: eca:ECA3055 bifunctional folylpolyglutamate synthase/dihydrofolate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein YP_003003713.1 PFAM: Sporulation domain protein; KEGG: eca:ECA3054 hypothetical protein YP_003003714.1 membrane protein required for colicin V production YP_003003715.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_003003716.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: yen:YE1317 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_003003717.1 KEGG: eca:ECA3050 histidine-binding periplasmic protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_003003718.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3049 histidine ABC transporter permease protein YP_003003719.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3048 histidine ABC transporter permease protein YP_003003720.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3047 histidine/lysine/arginine/ornithine transporter subunit YP_003003721.1 PFAM: domain of unknown function DUF1731; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA3046 hypothetical protein YP_003003722.1 PFAM: Glutathione S-transferase domain; KEGG: esa:ESA_00915 hypothetical protein YP_003003723.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: eca:ECA3043 phosphodiesterase YP_003003724.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA3042 putative NUDIX hydrolase YP_003003725.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_003003726.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_003003727.1 PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein YP_003003728.1 PFAM: YfbU family protein; KEGG: eca:ECA3037 hypothetical protein YP_003003729.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA3036 putative phosphatase YP_003003730.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: eca:ECA3035 putative sodium/sulphate transporter YP_003003731.1 KEGG: eca:ECA3034 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_003003732.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_003003734.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3032 LysR family transcriptional regulator YP_003003735.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003736.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_003003737.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_003003738.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: spe:Spro_3305 NADH dehydrogenase subunit E YP_003003739.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_003003740.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003741.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003742.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003743.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; KEGG: eca:ECA3020 NADH dehydrogenase subunit J YP_003003744.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003745.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_003003746.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003747.1 Catalyzes the transfer of electrons from NADH to quinone YP_003003748.1 PFAM: multicopper oxidase type 2; KEGG: xfn:XfasM23_2141 multicopper oxidase type 3 YP_003003749.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; proline racemase; KEGG: eca:ECA3011 hypothetical protein YP_003003750.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3010 ABC transporter ATP-binding protein YP_003003751.1 involved in hydrogen uptake YP_003003752.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_003003753.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_003003754.1 involved in hydrogen uptake YP_003003755.1 TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: yen:YE3605 hydrogenase 2 maturation endopeptidase YP_003003756.1 KEGG: yen:YE3604 hydrogenase 2-specific chaperone YP_003003757.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis HypA; KEGG: yen:YE3603a hydrogenase nickel incorporation protein HybF YP_003003758.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: pmr:PMI0037 hydrogenase nickel incorporation protein YP_003003759.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: yen:YE3602A hydrogenase 2 accessory protein HypG YP_003003760.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: pmr:PMI0039 hydrogenase formation protein YP_003003761.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: pmr:PMI0040 hydrogenase formation protein YP_003003762.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003003763.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: yen:YE3600 hydrogenase maturation protein YP_003003764.1 KEGG: eca:ECA3006 hypothetical protein YP_003003765.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_003003766.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: eca:ECA3004 transcription regulator GntR YP_003003767.1 KEGG: eca:ECA3326 hypothetical protein YP_003003768.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: eca:ECA1408 formate dehydrogenase, nitrate-inducible, major subunit YP_003003769.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: Formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: spe:Spro_0085 formate dehydrogenase, beta subunit YP_003003770.1 cytochrome b556(FDO) component; heme containing YP_003003771.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003003772.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_2307 major facilitator transporter YP_003003773.1 required for the formation of active formate dehydrogenase YP_003003774.1 KEGG: elf:LF82_p159 exported protein precursor YP_003003775.1 TIGRFAM: pectate lyase; KEGG: cja:CJA_0384 pectate lyase, putative, pel10C YP_003003776.1 PFAM: glycoside hydrolase family 43; KEGG: eca:ECA3847 putative xylosidase/arabinosidase YP_003003777.1 KEGG: ypy:YPK_0408 hypothetical protein YP_003003778.1 PFAM: Nitrate and nitrite sensing domain protein; ANTAR domain protein; KEGG: eca:ECA2995 nitrate-and nitrite-responsive positive regulator YP_003003779.1 KEGG: eca:ECA2994 nitrate-binding proteint YP_003003780.1 TIGRFAM: nitrate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2993 nitrate transporter permease component YP_003003781.1 KEGG: eca:ECA2992 nitrate transport protein; TIGRFAM: nitrate ABC transporter, ATPase subunits C and D; PFAM: ABC transporter related; SMART: AAA ATPase YP_003003782.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eca:ECA2991 nitrite reductase [NAD(P)H] large subunit YP_003003783.1 PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; molydopterin dinucleotide-binding region; KEGG: eca:ECA2990 nitrate reductase YP_003003784.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA2989 uroporphyrin-III C-methyltransferase YP_003003785.1 PFAM: NADPH-dependent FMN reductase; KEGG: dar:Daro_2797 NAD(P)H dehydrogenase (quinone):NADPH-dependent FMN reductase YP_003003786.1 KEGG: pha:PSHAa1464 hypothetical protein YP_003003788.1 KEGG: pfo:Pfl01_4299 hypothetical protein YP_003003789.1 KEGG: pfo:Pfl01_4299 hypothetical protein YP_003003790.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: ent:Ent638_1970 extracellular solute-binding protein YP_003003791.1 catalyzes the transfer of an amino moiety YP_003003792.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_1967 LysR family transcriptional regulator YP_003003793.1 PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: aha:AHA_2573 microcin immunity protein YP_003003794.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: ajs:Ajs_2152 methyl-accepting chemotaxis sensory transducer YP_003003795.1 PFAM: Ankyrin; SMART: Ankyrin; KEGG: vvu:VV2_0907 ankyrin repeateat-containing protein YP_003003796.1 KEGG: eca:ECA4379 gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_003003797.1 PFAM: glycosyl transferase family 28; KEGG: bam:Bamb_4507 glycosyl transferase family protein YP_003003798.1 KEGG: set:SEN0307 IS3 transposase YP_003003799.1 PFAM: regulatory protein TetR; KEGG: sek:SSPA2003 putative TetR-family transcriptional regulator YP_003003800.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: psb:Psyr_2283 secretion protein HlyD YP_003003801.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: dac:Daci_5856 RND efflux system outer membrane lipoprotein YP_003003802.1 KEGG: pfo:Pfl01_4305 hypothetical protein YP_003003803.1 PFAM: aldo/keto reductase; KEGG: gdj:Gdia_1683 aldo/keto reductase YP_003003805.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; KEGG: pfl:PFL_3016 helicase YP_003003806.1 KEGG: pfl:PFL_3015 hypothetical protein YP_003003807.1 KEGG: pfl:PFL_3014 hypothetical protein YP_003003808.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: pfl:PFL_3013 DNA-cytosine methyltransferase YP_003003809.1 KEGG: tgr:Tgr7_2822 hypothetical protein YP_003003810.1 PFAM: domain of unknown function DUF1738; KEGG: kpe:KPK_1761 putative antirestriction protein YP_003003811.1 PFAM: Post-segregation antitoxin CcdA; KEGG: spe:Spro_1554 post-segregation antitoxin CcdA YP_003003812.1 PFAM: CcdB protein; KEGG: spe:Spro_1555 CcdB protein YP_003003813.1 KEGG: kpe:KPK_1772 putative MobC protein YP_003003814.1 KEGG: kpe:KPK_1773 type IV conjugative transfer system coupling protein TraD YP_003003815.1 KEGG: kpe:KPK_1774 putative lipoprotein YP_003003816.1 TIGRFAM: P-type DNA transfer ATPase VirB11; PFAM: type II secretion system protein E; KEGG: eca:ECA1613 putative conjugal transfer protein YP_003003817.1 PFAM: conjugation TrbI family protein; KEGG: kpe:KPK_1776 bacterial conjugation TrbI-like protein YP_003003818.1 TIGRFAM: P-type conjugative transfer protein VirB9; PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: eca:ECA1615 putative conjugal transfer protein YP_003003819.1 PFAM: VirB8 family protein; KEGG: kpe:KPK_1778 type IV secretion system protein VirB8 YP_003003820.1 KEGG: kpe:KPK_1779 putative conjugal transfer protein YP_003003821.1 PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: eca:ECA1617 putative conjugal transfer protein YP_003003822.1 KEGG: ecq:ECED1_2265 conserved hypothetical protein; putative exported protein YP_003003823.1 PFAM: type IV secretion system family protein; KEGG: eca:ECA1619 putative conjugal transfer protein YP_003003824.1 PFAM: CagE TrbE VirB component of type IV transporter system; type IV secretory pathway VirB3 family protein; KEGG: eca:ECA1620 putative conjugal transfer protein YP_003003825.1 PFAM: Conjugal transfer protein TrbC; KEGG: eca:ECA1621 putative conjugal transfer protein YP_003003826.1 PFAM: Lytic transglycosylase catalytic; KEGG: eca:ECA1622 putative conjugal transfer protein YP_003003827.1 KEGG: eca:ECA1623 hypothetical protein YP_003003828.1 KEGG: shl:Shal_2175 hypothetical protein YP_003003829.1 PFAM: helicase domain protein; SMART: DEAD-like helicase; KEGG: shl:Shal_2176 helicase domain-containing protein YP_003003830.1 PFAM: transposase mutator type; KEGG: yps:YPTB0777 putative transposase-like protein YP_003003831.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: eca:ECA1625 putative conjugal transfer protein YP_003003832.1 KEGG: eca:ECA1626 hypothetical protein YP_003003833.1 PFAM: Prophage CP4-57 regulatory; KEGG: eca:ECA1627 putative prophage regulatory protein YP_003003834.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ses:SARI_03129 hypothetical protein YP_003003835.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ses:SARI_03130 hypothetical protein YP_003003836.1 KEGG: plu:plu0729 hypothetical protein YP_003003837.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcm:Bcenmc03_6923 XRE family transcriptional regulator YP_003003838.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA2866 hypothetical protein YP_003003839.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 putative rhs accessory genetic element YP_003003840.1 PFAM: Domain of unknown function DUF1795; KEGG: eca:ECA2868 hypothetical protein YP_003003841.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; PAAR repeat-containing protein; KEGG: eca:ECA4278 rhs-family protein YP_003003842.1 KEGG: spc:Sputcn32_3208 hypothetical protein YP_003003843.1 KEGG: btr:Btr_0399 hypothetical protein YP_003003844.1 KEGG: kpe:KPK_1790 hypothetical protein YP_003003845.1 PFAM: protein of unknown function DUF736; KEGG: pna:Pnap_4161 hypothetical protein YP_003003846.1 KEGG: pmr:PMI3401 sugar fermentation stimulation protein YP_003003847.1 KEGG: kpn:KPN_02949 putative transcriptional regulator YP_003003848.1 SMART: helix-turn-helix domain protein; KEGG: kpn:KPN_02949 putative transcriptional regulator YP_003003849.1 PFAM: integrase family protein; KEGG: kpe:KPK_1799 integrase YP_003003850.1 PFAM: regulatory protein LysR; KEGG: eca:ECA2888 nitrogen assimilation regulatory protein (partial) YP_003003851.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA2885 D-alanine/D-serine/glycine permease YP_003003852.1 KEGG: eca:ECA2883 hypothetical protein YP_003003853.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_003003854.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_003003855.1 KEGG: yen:YE1829 phosphatidylglycerophosphate synthetase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_003003856.1 KEGG: ent:Ent638_1341 hypothetical protein YP_003003857.1 KEGG: yps:YPTB1774 putative integrase YP_003003859.1 KEGG: eca:ECA2615 putative phage encoded host lysis, regulatory protein YP_003003860.1 PFAM: glycoside hydrolase family 24; KEGG: kpn:KPN_04875 putative prophage endolysin, control of lysis YP_003003861.1 PFAM: holin family 2; KEGG: eca:ECA2617 phage lysis protein Y, holin YP_003003862.1 SMART: Parallel beta-helix repeat; KEGG: sde:Sde_2946 hypothetical protein YP_003003863.1 KEGG: pat:Patl_1404 cellulase; PFAM: glycoside hydrolase family 5; Carbohydrate-binding family V/XII; SMART: Carbohydrate-binding family V/XII YP_003003864.1 PFAM: cytochrome b562; KEGG: eca:ECA2222 putative soluble cytochrome b562 YP_003003865.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: eca:ECA2762 hypothetical protein YP_003003867.1 KEGG: eca:ECA1682 hypothetical protein YP_003003868.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1683 methyl-accepting chemotaxis protein YP_003003869.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_003003870.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_003003871.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_003003872.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_003003873.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_003003874.1 PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: eca:ECA1690 purine-binding chemotaxis protein YP_003003875.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: eca:ECA1691 methyl-accepting chemotaxis protein YP_003003876.1 methylates the MCP YP_003003877.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_003003878.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA1694 chemotaxis regulatory protein CheY YP_003003879.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_003003880.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_003003881.1 membrane protein involved in the flagellar export apparatus YP_003003882.1 PFAM: flagellar FlhE family protein; KEGG: eta:ETA_14740 flagellar protein FlhE YP_003003883.1 PFAM: FlgN family protein; KEGG: eca:ECA1699 flagella synthesis protein YP_003003884.1 regulates the flagellar specific sigma28 transcription factor YP_003003885.1 required for the assembly of the flagellar basal body P-ring YP_003003886.1 TIGRFAM: flagellar basal-body rod protein FlgB; PFAM: flagellar basal body rod protein; KEGG: eca:ECA1702 flagellar basal body rod protein FlgB YP_003003887.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_003003888.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_003003889.1 the hook connects flagellar basal body to the flagellar filament YP_003003890.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: eca:ECA1706 flagellar basal body rod protein FlgF YP_003003891.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: eca:ECA1707 flagellar basal body rod protein FlgG YP_003003892.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_003003893.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_003003894.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_003003895.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: eca:ECA1711 flagellar hook-associated protein FlgK YP_003003896.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: eca:ECA1712 flagellar hook-associated protein FlgL YP_003003897.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: eca:ECA1714 flagellar biosynthesis protein FliR YP_003003898.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_003003899.1 TIGRFAM: flagellar biosynthetic protein FliP; PFAM: type III secretion system inner membrane P protein; KEGG: eca:ECA1716 flagellar biosynthesis protein FliP YP_003003900.1 PFAM: flagellar biosynthesis protein FliO; KEGG: eca:ECA1717 flagellar protein YP_003003901.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: eca:ECA1718 flagellar motor switch protein FliN YP_003003902.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_003003903.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_003003904.1 PFAM: flagellar hook-length control protein; KEGG: eca:ECA1721 flagellar hook-length control protein YP_003003905.1 rod/hook and filament chaperone YP_003003906.1 involved in type III protein export during flagellum assembly YP_003003907.1 binds to and inhibits the function of flagella specific ATPase FliI YP_003003908.1 One of three proteins involved in switching the direction of the flagellar rotation YP_003003909.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_003003910.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: eca:ECA1727 flagellar hook-basal body protein FliE YP_003003911.1 PFAM: flagellar export chaperone; KEGG: eca:ECA1728 flagellar biosynthesis protein FliT YP_003003912.1 TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; KEGG: eca:ECA1729 flagellar protein FliS YP_003003913.1 PFAM: flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook-associated protein 2 domain protein; KEGG: yps:YPTB1713 flagellar capping protein YP_003003914.1 PFAM: flagellin domain protein; KEGG: esa:ESA_01288 hypothetical protein YP_003003915.1 PFAM: Methyltransferase type 12; KEGG: eca:ECA1732 hypothetical protein YP_003003916.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: cko:CKO_01022 hypothetical protein YP_003003917.1 KEGG: rec:RHECIAT_CH0001589 putative carbamoyl-phosphate-synthetase protein YP_003003918.1 PFAM: oxidoreductase domain protein; KEGG: ret:RHE_CH01518 putative oxidoreductase protein YP_003003919.1 KEGG: ent:Ent638_2521 hypothetical protein YP_003003921.1 KEGG: plu:plu4438 IS630 family transposase YP_003003922.1 KEGG: bcj:pBCA012 hypothetical protein YP_003003923.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_003003924.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_003003926.1 PFAM: PhoH family protein; KEGG: eca:ECA1741 hypothetical protein YP_003003927.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA3245 methyl-accepting chemotaxis protein YP_003003928.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003003929.1 PFAM: Ribose/galactose isomerase; KEGG: eca:ECA1742 hypothetical protein YP_003003930.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_003003931.1 KEGG: eca:ECA1749 hypothetical protein YP_003003932.1 PFAM: protein of unknown function DUF1047; KEGG: eca:ECA1750 hypothetical protein YP_003003933.1 KEGG: eca:ECA1771 hypothetical protein YP_003003934.1 KEGG: eca:ECA1773 hypothetical protein YP_003003935.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1774 methyl-accepting chemotaxis protein YP_003003936.1 KEGG: eca:ECA1775 putative iron-regulated membrane protein YP_003003937.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_003003938.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_003003939.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: eca:ECA1779 lipid A biosynthesis lauroyl acyltransferase YP_003003940.1 PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: spe:Spro_1886 hypothetical protein YP_003003941.1 PFAM: YceI family protein; KEGG: sfx:S1140 hypothetical protein YP_003003942.1 PFAM: cytochrome B561; KEGG: eca:ECA1783 hypothetical protein YP_003003943.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_003003944.1 PFAM: DinI family protein; KEGG: eca:ECA1786 DNA damage-inducible protein I YP_003003945.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_003003946.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: eca:ECA1788 hypothetical protein YP_003003947.1 KEGG: eca:ECA1789 ribonuclease E; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; SMART: RNA binding S1 domain protein YP_003003948.1 KEGG: eca:ECA1790 23S rRNA pseudouridylate synthase C; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein YP_003003949.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: eca:ECA1791 Maf-like protein YP_003003950.1 PFAM: protein of unknown function DUF177; KEGG: eca:ECA1792 hypothetical protein YP_003003951.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_003003952.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_003003953.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_003003954.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: eca:ECA1796 acyl carrier protein S-malonyltransferase YP_003003955.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA1797 3-ketoacyl-(acyl-carrier-protein) reductase YP_003003956.1 carries the fatty acid chain in fatty acid biosynthesis YP_003003957.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003003958.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_003003959.1 PFAM: aminodeoxychorismate lyase; KEGG: eca:ECA1801 aminodeoxychorismate lyase YP_003003960.1 KEGG: ypi:YpsIP31758_1583 thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: thymidylate kinase YP_003003961.1 KEGG: eca:ECA1803 DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: DNA polymerase III delta subunit YP_003003962.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: eca:ECA1804 putative metallodependent hydrolase YP_003003963.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003003964.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: lhk:LHK_00733 malate/L-lactate dehydrogenase YP_003003965.1 PFAM: histidine triad (HIT) protein; KEGG: eca:ECA1809 purine nucleoside phosphoramidase YP_003003966.1 PFAM: protein of unknown function DUF1425; KEGG: eca:ECA1810 putative lipoprotein YP_003003967.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: eca:ECA1811 putative lipoprotein YP_003003968.1 PFAM: aminoglycoside phosphotransferase; KEGG: eca:ECA1812 hypothetical protein YP_003003969.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_003003970.1 PFAM: protein of unknown function UPF0227; KEGG: esa:ESA_02236 hypothetical protein YP_003003971.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA1815 NADH dehydrogenase YP_003003972.1 PFAM: 17 kDa surface antigen; KEGG: eca:ECA1816 hypothetical protein YP_003003973.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA1966 putative transcriptional repressor YP_003003974.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1967 putative hexuronate transporter YP_003003975.1 PFAM: glycoside hydrolase family 31; KEGG: eca:ECA1968 putative glycosyl hydrolase YP_003003976.1 PFAM: N-acetyltransferase; KEGG: spe:Spro_1338 N-acetyltransferase YP_003003977.1 KEGG: eca:ECA1820 putative chaperone YP_003003978.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: yen:YE1560 hypothetical protein YP_003003979.1 KEGG: eca:ECA1821 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: TRCF domain protein; transcription factor CarD; helicase domain protein; DEAD/DEAH box helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase ; helicase domain protein YP_003003980.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_003003981.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_003003982.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_003003983.1 PFAM: ROK family protein; KEGG: yps:YPTB2439 N-acetyl-D-glucosamine kinase YP_003003984.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_003003985.1 KEGG: eca:ECA1828 hypothetical protein YP_003003986.1 with BtuD and BtuF transports vitamin B12 into the cell YP_003003987.1 PFAM: glutathione peroxidase; KEGG: yen:YE2194 putative glutathione peroxidase YP_003003988.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1834 vitamin B12-transporter ATPase YP_003003989.1 PFAM: NLP/P60 protein; KEGG: spe:Spro_2161 NLP/P60 protein YP_003003990.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eca:ECA1841 hypothetical protein YP_003003991.1 PFAM: protein of unknown function UPF0061; KEGG: eca:ECA1842 hypothetical protein YP_003003992.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; KEGG: eca:ECA2546 hypothetical protein YP_003003993.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: eca:ECA2545 hypothetical protein YP_003003994.1 PFAM: beta-lactamase domain protein; KEGG: eca:ECA2544 putative metallo-beta-lactamase YP_003003995.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: aha:AHA_1290 radical SAM domain-containing protein YP_003003996.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_003003997.1 PFAM: porin Gram-negative type; KEGG: eca:ECA2542 outer membrane protein YP_003003998.1 PFAM: porin Gram-negative type; KEGG: eca:ECA2542 outer membrane protein YP_003003999.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003004000.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_003004001.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: eca:ECA2539 aminopeptidase N YP_003004002.1 KEGG: lhk:LHK_01781 ATPases with chaperone activity, ATP-binding subunit YP_003004003.1 KEGG: lhk:LHK_01780 hypothetical protein YP_003004004.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_003004005.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: esa:ESA_02406 alkanesulfonate transporter permease subunit YP_003004006.1 catalyzes the release of sulfite from alkanesulfonates YP_003004007.1 KEGG: spe:Spro_1738 alkanesulfonate transporter substrate-binding subunit; TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein family 3 YP_003004008.1 PFAM: NADPH-dependent FMN reductase; KEGG: kpe:KPK_3595 NADPH-dependent FMN reductase YP_003004009.1 KEGG: eca:ECA2538 dihydroorotate dehydrogenase 2; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase YP_003004010.1 PFAM: protein of unknown function DUF1379; KEGG: eca:ECA2537 hypothetical protein YP_003004011.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; ferredoxin; KEGG: spe:Spro_1742 MOSC domain-containing protein YP_003004012.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_003004013.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_003004014.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: eca:ECA2533 paraquat-inducible protein A YP_003004015.1 PFAM: Mammalian cell entry related domain protein; KEGG: eca:ECA2532 paraquat-inducible protein B YP_003004016.1 PFAM: protein of unknown function DUF330; KEGG: eca:ECA2531 putative lipoprotein YP_003004017.1 PFAM: ribosome modulation factor; KEGG: yps:YPTB1448 putative ribosome modulation factor YP_003004018.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_003004020.1 PFAM: protein of unknown function DUF299; KEGG: eca:ECA1852 hypothetical protein YP_003004021.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003004022.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_003004023.1 PFAM: FAD linked oxidase domain protein; KEGG: eca:ECA1856 putative FAD-binding oxidase YP_003004024.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA1857 hypothetical protein YP_003004025.1 KEGG: eca:ECA1858 hypothetical protein YP_003004026.1 TIGRFAM: FeS assembly scaffold SufA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: eca:ECA1859 iron-sulfur cluster assembly scaffold protein YP_003004027.1 with SufCD activates cysteine desulfurase SufS YP_003004028.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_003004029.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: eca:ECA1862 cysteine desulfurase activator complex subunit SufD YP_003004030.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: eca:ECA1863 selenocysteine lyase YP_003004031.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_003004032.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA1865 hypothetical protein YP_003004033.1 PFAM: LPP repeat-containing protein; KEGG: eca:ECA1866 major outer membrane lipoprotein YP_003004034.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003004035.1 PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: eca:ECA1869 beta-glucoside operon antiterminator YP_003004036.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003004037.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA1871 6-phospho-beta-glucosidase YP_003004038.1 PFAM: porin LamB type; KEGG: efe:EFER_4018 carbohydrate-specific outer membrane porin, cryptic YP_003004039.1 PFAM: putative esterase; glycoside hydrolase family 13 domain protein; KEGG: eca:ECA1873 putative glycosyl hydrolase exoenzyme YP_003004040.1 KEGG: pla:Plav_3399 hypothetical protein YP_003004041.1 KEGG: bid:Bind_1489 hypothetical protein YP_003004042.1 PFAM: NmrA family protein; KEGG: rpd:RPD_2341 NmrA-like YP_003004043.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: rlt:Rleg2_6348 transcriptional regulator, AraC family YP_003004044.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_003004045.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_003004046.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_003004047.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_003004049.1 PFAM: NLP/P60 protein; KEGG: eca:ECA1926 hypothetical protein YP_003004050.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: eca:ECA1927 hypothetical protein YP_003004051.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_003004052.1 KEGG: spe:Spro_2200 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_003004053.1 Transcription regulator that can both activate or repress expression YP_003004054.1 PFAM: 17 kDa surface antigen; KEGG: eca:ECA1932 outer membrane lipoprotein YP_003004055.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_003004056.1 KEGG: eca:ECA1934 putative lipoprotein YP_003004057.1 KEGG: eca:ECA1935 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding YP_003004058.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_003004059.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_003004060.1 PFAM: Glutathione S-transferase domain; KEGG: eca:ECA1938 glutathione S-transferase YP_003004061.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: eca:ECA1941 aconitate hydratase YP_003004062.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1942 putative periplasmic oligopeptide-binding protein YP_003004063.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_003004064.1 KEGG: eca:ECA1944 phosphatidylglycerophosphatase B; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related YP_003004065.1 PFAM: protein of unknown function DUF1049; KEGG: eca:ECA1955 hypothetical protein YP_003004066.1 SMART: Tetratricopeptide domain protein; KEGG: eca:ECA1956 hypothetical protein YP_003004067.1 KEGG: eta:ETA_16210 orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase YP_003004068.1 TIGRFAM: translation initiation factor SUI1; PFAM: translation initiation factor SUI1; KEGG: eum:ECUMN_1585 hypothetical protein YP_003004069.1 KEGG: ent:Ent638_2185 lipoprotein YP_003004070.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003004071.1 transports degraded pectin products into the bacterial cell YP_003004072.1 PFAM: carbon starvation protein CstA; KEGG: eca:ECA1961 carbon starvation protein YP_003004073.1 PFAM: aldo/keto reductase; KEGG: eca:ECA1962 putative oxidoreductase YP_003004074.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_003004075.1 KEGG: nmn:NMCC_0222 putative inner membrane protein YP_003004077.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase; KEGG: eca:ECA1964 putative molybdopterin oxidoreductase YP_003004078.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_003004079.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1973 peptide transport system ATP-binding protein YP_003004080.1 KEGG: eca:ECA1974 peptide transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_003004081.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1975 peptide transport system permease protein YP_003004082.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1976 peptide transport system permease protein YP_003004083.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1977 peptide transport periplasmic protein YP_003004084.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_003004085.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_003004086.1 TIGRFAM: phage shock protein B; PFAM: shock B family protein; KEGG: eca:ECA1984 phage shock protein B YP_003004087.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_003004088.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: eca:ECA1986 hypothetical protein YP_003004089.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1987 hypothetical protein YP_003004090.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: spe:Spro_3193 major facilitator transporter YP_003004091.1 PFAM: peptidase dimerisation domain protein; KEGG: eca:ECA1988 putative peptidase YP_003004092.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_003004095.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aha:AHA_0446 putative acetyltransferase YP_003004096.1 PFAM: peptidase S45 penicillin amidase; KEGG: bpl:BURPS1106A_0792 putative penicillin amidase YP_003004097.1 SMART: helix-turn-helix domain protein; KEGG: pap:PSPA7_4128 hypothetical protein YP_003004098.1 PFAM: major facilitator superfamily MFS_1; KEGG: pae:PA1262 major facilitator transporter YP_003004099.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_003004100.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: efe:EFER_1648 murein peptide amidase A YP_003004101.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1992 periplasmic murein peptide-binding protein YP_003004103.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: eca:ECA1993 zinc transporter YP_003004104.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_003004105.1 KEGG: pst:PSPTO_5206 EF hand domain-containing protein YP_003004107.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2580 putative methyl-accepting chemotaxis citrate transducer YP_003004108.1 PFAM: protein of unknown function DUF333; KEGG: eca:ECA1999 putative lipoprotein YP_003004109.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: eca:ECA2000 D-lactate dehydrogenase YP_003004110.1 KEGG: eca:ECA2002 aerotaxis receptor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; PAC repeat-containing protein YP_003004111.1 KEGG: eca:ECA2003 hypothetical protein YP_003004112.1 KEGG: eca:ECA2004 putative lipoprotein YP_003004113.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_003004114.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_003004115.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: eca:ECA1921 L-lactate permease YP_003004116.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: eca:ECA2009 putative exported protease YP_003004118.1 KEGG: hypothetical protein YP_003004119.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA2012 sensor protein RstB YP_003004120.1 response regulator in two-component regulatory system with RstB YP_003004121.1 KEGG: spe:Spro_2588 hypothetical protein YP_003004122.1 TIGRFAM: sulfate transporter; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; KEGG: eca:ECA2021 putative sulfate transporter YchM YP_003004123.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: eca:ECA2022 calcium/sodium:proton antiporter YP_003004124.1 PFAM: ChaC family protein; KEGG: eca:ECA2025 putative cation transport protein YP_003004125.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_2915 binding-protein-dependent transport systems inner membrane component YP_003004126.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_2914 binding-protein-dependent transport systems inner membrane component YP_003004127.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_2913 ABC transporter-related protein YP_003004128.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_2060 ABC transporter related YP_003004129.1 PFAM: extracellular solute-binding protein family 5; KEGG: eta:ETA_25780 ABC transporter, periplasmic oligopeptide-binding protein YP_003004130.1 PFAM: metallophosphoesterase; KEGG: eum:ECUMN_2132 serine/threonine-specific protein phosphatase 1 YP_003004131.1 KEGG: kpn:KPN_00487 hypothetical protein YP_003004132.1 KEGG: eta:ETA_30660 methyl-accepting chemotaxis sensory transducer; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; PAS domain containing protein YP_003004134.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: spe:Spro_2983 methyl-accepting chemotaxis sensory transducer YP_003004135.1 KEGG: spe:Spro_2420 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein YP_003004137.1 TIGRFAM: guanine deaminase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: vha:VIBHAR_01787 hypothetical protein YP_003004138.1 PFAM: transcriptional activator Ogr/delta; KEGG: ent:Ent638_3475 DNA-binding transcriptional regulator YP_003004139.1 PFAM: late control D family protein; KEGG: ecg:E2348C_2892 predicted late gene regulator YP_003004140.1 PFAM: P2 GpU family protein; KEGG: yps:YPTB1740 putative phage tail protein YP_003004141.1 KEGG: GG20978 gene product from transcript GG20978-RA YP_003004142.1 PFAM: P2 GpE family protein; KEGG: ecm:EcSMS35_4348 phage tail protein, P2 GpE family YP_003004143.1 PFAM: tail E family protein; KEGG: ecz:ECS88_2189 tail protein E (GpE) YP_003004144.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: see:SNSL254_A4384 phage major tail tube protein YP_003004145.1 PFAM: tail sheath protein; KEGG: spe:Spro_0863 tail sheath protein YP_003004146.1 PFAM: tail assembly chaperone gp38; KEGG: plu:plu2035 hypothetical protein YP_003004147.1 PFAM: Tail Collar domain protein; KEGG: sty:STY1642 alternative bacteriophage tail fiber C-terminus YP_003004148.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: kpe:KPK_2840 DNA-invertase hin YP_003004149.1 PFAM: Tail Collar domain protein; KEGG: stt:t3433 variable tail fiber protein YP_003004150.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: esa:ESA_01951 hypothetical protein YP_003004151.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: spe:Spro_2512 major facilitator transporter YP_003004152.1 KEGG: spe:Spro_1010 hypothetical protein YP_003004153.1 PFAM: Tail Collar domain protein; KEGG: eta:ETA_05860 putative phage tail fiber protein YP_003004154.1 TIGRFAM: phage tail protein I; KEGG: yps:YPTB1748 putative bacteriophage protein YP_003004155.1 PFAM: Baseplate J family protein; KEGG: ecf:ECH74115_3037 baseplate assembly protein GpJ YP_003004156.1 PFAM: GPW/gp25 family protein; KEGG: kpn:KPN_04869 putative prophage baseplate protein YP_003004157.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: ecm:EcSMS35_4337 phage baseplate assembly protein GpV YP_003004158.1 PFAM: P2 phage tail completion R family protein; KEGG: kpn:KPN_04873 putative prophage, tail completion protein YP_003004159.1 PFAM: tail X family protein; KEGG: eta:ETA_05750 putative phage tail protein YP_003004162.1 PFAM: replication gene A; KEGG: spe:Spro_0874 replication gene A YP_003004163.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: yen:YE1687 hypothetical protein YP_003004165.1 KEGG: ecz:ECS88_2224 replication gene B protein (GpB) YP_003004167.1 PFAM: CI repressor; KEGG: spe:Spro_0877 CI repressor YP_003004168.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: ypg:YpAngola_A3774 methyl-accepting chemotaxis protein YP_003004169.1 PFAM: protein of unknown function DUF1482; KEGG: kpn:KPN_02353 hypothetical protein YP_003004170.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_003004171.1 PFAM: Mammalian cell entry related domain protein; KEGG: eca:ECA2463 hypothetical protein YP_003004172.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: eca:ECA2462 hypothetical protein YP_003004173.1 PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: eca:ECA2461 hypothetical protein YP_003004174.1 affects solute and DNA transport through an unknown mechanism YP_003004175.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_003004176.1 PFAM: protein of unknown function DUF481; KEGG: eca:ECA2026 hypothetical protein YP_003004177.1 PFAM: acyltransferase 3; KEGG: eca:ECA2027 putative acyltransferase YP_003004178.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_003004179.1 KEGG: eca:ECA2029 nitrate/nitrite sensor protein NarX; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein YP_003004180.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2030 nitrite extrusion protein YP_003004181.1 PFAM: beta-lactamase domain protein; KEGG: eca:ECA2849 metallo-beta-lactamase YP_003004182.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2848 LysR family transcriptional regulator YP_003004183.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: eca:ECA2031 respiratory nitrate reductase 1 alpha chain YP_003004184.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: eca:ECA2032 respiratory nitrate reductase 1 beta chain YP_003004185.1 KEGG: eca:ECA2033 respiratory nitrate reductase 1 delta chain; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit YP_003004186.1 KEGG: kpe:KPK_2098 respiratory nitrate reductase 1, gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit YP_003004187.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ilo:IL0796 alcohol dehydrogenase YP_003004188.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: ses:SARI_01418 hypothetical protein YP_003004189.1 TIGRFAM: death-on-curing family protein; PFAM: filamentation induced by cAMP protein Fic; KEGG: ses:SARI_01417 hypothetical protein YP_003004190.1 KEGG: vpa:VP1851 hypothetical protein YP_003004191.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_003004192.1 PFAM: Domain of unknown function DUF1852; KEGG: spe:Spro_3175 hypothetical protein YP_003004193.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: esa:ESA_01873 4-oxalocrotonate tautomerase YP_003004194.1 KEGG: eca:ECA2051 putitive ABC-transporter ATP-binding protein; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_003004195.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: eca:ECA2052 GntR family transcriptional regulator YP_003004196.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_003004197.1 KEGG: eca:ECA2054 succinate-semialdehyde dehydrogenase [NADP+]; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase YP_003004198.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2055 putative transport system, periplasmic solute-binding protein YP_003004199.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2056 putative transport system, permease protein YP_003004200.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2057 putative transport system, permease protein YP_003004201.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: spe:Spro_3091 LysR family transcriptional regulator YP_003004202.1 PFAM: Glutathione S-transferase domain; KEGG: spe:Spro_3092 glutathione S-transferase domain-containing protein YP_003004203.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: spe:Spro_3093 pyridoxamine 5'-phosphate oxidase-related FMN-binding YP_003004204.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA1907 DeoR family transcriptional regulator YP_003004205.1 TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: eca:ECA2167 putative inositol monophosphatase YP_003004206.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfo:Pfl01_3782 major facilitator transporter YP_003004207.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: eca:ECA1906 putative hydrolase YP_003004208.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: ypg:YpAngola_A3774 methyl-accepting chemotaxis protein YP_003004209.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_003004211.1 TIGRFAM: type III secretion protein, YscU/HrpY family; PFAM: type III secretion exporter; KEGG: eca:ECA2076 type III secretion protein YP_003004212.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: eca:ECA2077 type III secretion protein YP_003004213.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ family 3; KEGG: eta:ETA_05140 HrcS protein (hrp cluster) YP_003004214.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_003004215.1 TIGRFAM: type III secretion system apparatus protein YscQ/HrcQ; PFAM: surface presentation of antigens (SPOA) protein; KEGG: eca:ECA2080 type III secretion protein YP_003004216.1 KEGG: eca:ECA2081 type III secretion protein YP_003004217.1 KEGG: eca:ECA2082 type III secretion protein YP_003004218.1 KEGG: eca:ECA2083 type III secretion protein; TIGRFAM: type III secretion apparatus H+-transporting two-sector ATPase; ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase YP_003004219.1 TIGRFAM: type III secretion apparatus protein, YscD/HrpQ family; PFAM: Forkhead-associated protein; KEGG: eca:ECA2084 type III secretion protein YP_003004220.1 TIGRFAM: type III secretion protein, HrcV family; PFAM: type III secretion FHIPEP protein; KEGG: eca:ECA2085 type III secretion protein YP_003004221.1 TIGRFAM: type III secretion regulator YopN/LcrE/InvE/MxiC; type III secretion effector delivery regulator, TyeA family; PFAM: Hypersensitivity response secretion HrpJ domain protein; KEGG: eca:ECA2086 type III secretion protein YP_003004222.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: eca:ECA2087 sigma factor YP_003004223.1 KEGG: eca:ECA2088 two-component sensor kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation and phosphoacceptor region; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein YP_003004224.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: eca:ECA2089 two-component response regulator YP_003004225.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: eca:ECA2090 sigma-54-dependent enhancer-binding protein YP_003004226.1 KEGG: eca:ECA2093 type III secretion protein YP_003004227.1 TIGRFAM: type III secretion apparatus protein, YscI/HrpB family; KEGG: eca:ECA2094 type III secretion protein YP_003004228.1 TIGRFAM: type III secretion apparatus lipoprotein, YscJ/HrcJ family; PFAM: secretory protein YscJ/FliF family protein; KEGG: eca:ECA2095 type III secretion protein YP_003004229.1 KEGG: eca:ECA2096 type III secretion protein YP_003004230.1 TIGRFAM: type III secretion apparatus protein, HrpE/YscL family; PFAM: HrpE family protein; KEGG: eca:ECA2097 type III secretion protein YP_003004231.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: pap:PSPA7_1115 putative lipoprotein YP_003004232.1 KEGG: hch:HCH_03110 alpha/beta fold family hydrolase YP_003004234.1 PFAM: HrpF family protein; KEGG: eca:ECA2098 type III secretion protein YP_003004235.1 KEGG: eca:ECA2099 type III secretion protein YP_003004236.1 TIGRFAM: type III secretion outer membrane pore, YscC/HrcC family; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: eca:ECA2100 type III secretion protein YP_003004237.1 KEGG: eca:ECA2101 type III secretion lipoprotein YP_003004238.1 KEGG: eta:ETA_05360 HrpV protein (hrp cluster) YP_003004239.1 PFAM: Harpin family protein; KEGG: eca:ECA2103 harpin YP_003004240.1 PFAM: Cupin 2 conserved barrel domain protein; Cupin domain protein; KEGG: hch:HCH_03272 mannose-6-phosphate isomerase YP_003004241.1 PFAM: Polypeptide-transport-associated domain protein ShlB-type; Hemolysin activator HlyB domain protein; KEGG: eca:ECA2116 putative hemolysin activator protein YP_003004242.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentous haemagglutinin domain protein; Haemagluttinin repeat-containing protein; protein of unknown function DUF638 hemagglutinin/hemolysin putative; KEGG: ent:Ent638_0053 filamentous haemagglutinin outer membrane protein YP_003004244.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_003004245.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3417 putative phage regulatory protein YP_003004246.1 PFAM: zinc finger CHC2-family protein; DNA primase catalytic core domain; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; KEGG: plu:plu3714 hypothetical protein YP_003004247.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003004248.1 KEGG: ypi:YpsIP31758_0519 hypothetical protein YP_003004249.1 KEGG: pap:PSPA7_0046 hypothetical protein YP_003004250.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_003004251.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3417 putative phage regulatory protein YP_003004252.1 PFAM: zinc finger CHC2-family protein; DNA primase catalytic core domain; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; KEGG: plu:plu3714 hypothetical protein YP_003004253.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003004254.1 KEGG: eta:ETA_19590 hypothetical protein YP_003004255.1 KEGG: plu:plu0222 hypothetical protein YP_003004256.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_003004257.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: ecm:EcSMS35_3216 putative addiction module antidote protein, CC2985 family YP_003004258.1 PFAM: plasmid stabilization system; KEGG: rso:RSc3224 hypothetical protein YP_003004259.1 PFAM: FeoA family protein; KEGG: rru:Rru_A2468 hypothetical protein YP_003004260.1 PFAM: FeoA family protein; KEGG: rru:Rru_A2469 hypothetical protein YP_003004261.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; KEGG: rru:Rru_A2470 ferrous iron transport protein B YP_003004262.1 PFAM: Protein of unknown function DUF1920; KEGG: rru:Rru_A2471 hypothetical protein YP_003004264.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_003004265.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: eca:ECA2447 hypothetical protein YP_003004266.1 PFAM: PhoQ Sensor domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: eca:ECA2446 sensor protein PhoQ YP_003004267.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_003004268.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_003004269.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_003004270.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_003004271.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA2441 putative MutT family protein YP_003004272.1 PFAM: pseudouridine synthase; KEGG: eca:ECA2440 putative RNA pseudouridylate synthase YP_003004273.1 Converts isocitrate to alpha ketoglutarate YP_003004274.1 KEGG: eca:ECA2433 putative signaling protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS domain containing protein YP_003004275.1 PFAM: HtpX domain protein; peptidase M48 Ste24p; KEGG: eca:ECA2427 heat shock protein HtpX YP_003004276.1 KEGG: eca:ECA2426 oligogalacturonate lyase YP_003004277.1 PFAM: Transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: eca:ECA2425 pectin degradation repressor YP_003004278.1 KEGG: eca:ECA2424 hypothetical protein YP_003004279.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003004280.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_003004281.1 TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: eta:ETA_18390 50S ribosomal protein L35 YP_003004282.1 TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; KEGG: eca:ECA2419 50S ribosomal protein L20 YP_003004283.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_003004284.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_003004285.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_003004286.1 KEGG: pmr:PMI1959 hypothetical protein YP_003004287.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA2413 hypothetical protein YP_003004288.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_003004289.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_003004290.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA2410 putative sodium:dicarboxylate symporter YP_003004291.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: eca:ECA2409 hypothetical protein YP_003004292.1 KEGG: eca:ECA2408 pectin acetylesterase YP_003004293.1 PFAM: Oligogalacturonate-specific porin; KEGG: eca:ECA2407 oligogalacturonate-specific porin YP_003004294.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2406 periplasmic pectic oligomers binding protein YP_003004295.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: eca:ECA2405 ABC transporter, ATP-binding component YP_003004296.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ent:Ent638_3290 binding-protein-dependent transport systems inner membrane component YP_003004297.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2403 binding-protein-dependent transport system, inner membrane component YP_003004298.1 PFAM: periplasmic pectate lyase; KEGG: eca:ECA2402 pectate disaccharide-lyase YP_003004299.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_003004300.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_003004301.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: eca:ECA2399 pectin degradation protein YP_003004302.1 KEGG: eca:ECA2397 hypothetical protein YP_003004303.1 PFAM: fructosamine kinase; aminoglycoside phosphotransferase; KEGG: eca:ECA2396 putative fructosamine kinase YP_003004304.1 PFAM: transposase IS4 family protein; KEGG: sfx:S4808 hypothetical protein YP_003004305.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: eca:ECA2391 cold shock-like protein CspC YP_003004306.1 PFAM: Methyltransferase type 11; KEGG: eca:ECA2390 23S rRNA methyltransferase A YP_003004307.1 PFAM: protein of unknown function DUF204; KEGG: eca:ECA2389 hypothetical protein YP_003004308.1 PFAM: protein of unknown function DUF986; KEGG: ypi:YpsIP31758_2371 hypothetical protein YP_003004309.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_003004310.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: eca:ECA2386 PTS system, mannose-specific IIC component YP_003004311.1 KEGG: eca:ECA2385 PTS system, mannose-specific IIAB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system sorbose subfamily IIB component; PTS system fructose subfamily IIA component YP_003004312.1 PFAM: Integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA2384 hypothetical protein YP_003004313.1 KEGG: eca:ECA2380 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_003004314.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA2379 hypothetical protein YP_003004315.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: yen:YE1781 para-aminobenzoate synthase component I YP_003004316.1 PFAM: protein of unknown function UPF0181; KEGG: eum:ECUMN_2103 hypothetical protein YP_003004317.1 PFAM: Endoribonuclease L-PSP; KEGG: eca:ECA2376 putative endoribonuclease YP_003004318.1 SMART: helicase c2; DEAD-like helicase; KEGG: eca:ECA2375 putative ATP-dependent helicase YP_003004319.1 PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein YP_003004320.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: eca:ECA2373 outer membrane lipoprotein YP_003004321.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA2372 long-chain-fatty-acid--CoA ligase YP_003004322.1 KEGG: eca:ECA2371 ribonuclease D; TIGRFAM: ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein YP_003004323.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_003004324.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_003004325.1 blocks the formation of polar Z-ring septums YP_003004326.1 PFAM: protein of unknown function DUF709; KEGG: elf:LF82_2733 uncharacterized protein ycgl YP_003004327.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: eca:ECA2366 hypothetical protein YP_003004328.1 PFAM: protein of unknown function UPF0153; KEGG: eca:ECA2365 hypothetical protein YP_003004329.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_003004330.1 Multifunctional regulator of fatty acid metabolism YP_003004331.1 PFAM: SpoVR family protein; KEGG: eca:ECA2359 hypothetical protein YP_003004332.1 catalyzes the oxidative deamination of D-amino acids YP_003004333.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_003004334.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentous haemagglutinin domain protein; Haemagluttinin repeat-containing protein; protein of unknown function DUF638 hemagglutinin/hemolysin putative; KEGG: ent:Ent638_0053 filamentous haemagglutinin outer membrane protein YP_003004335.1 KEGG: plu:plu1122 hypothetical protein YP_003004336.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: plu:plu3380 hypothetical protein YP_003004337.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: ecm:EcSMS35_3216 putative addiction module antidote protein, CC2985 family YP_003004338.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2134 ABC transporter, substrate binding protein YP_003004339.1 KEGG: hypothetical protein LOC100013487 YP_003004340.1 PFAM: transposase IS4 family protein; KEGG: sfx:S4808 hypothetical protein YP_003004341.1 KEGG: eca:ECA2139 hypothetical protein YP_003004342.1 KEGG: pst:PSPTO_1405 type III helper protein HrpK1 YP_003004343.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: yen:YE3176 short chain dehydrogenase YP_003004344.1 KEGG: eca:ECA2111 potential HrpW-specific chaperone YP_003004345.1 PFAM: Pectate lyase; KEGG: eca:ECA2112 type III effector protein YP_003004346.1 KEGG: eca:ECA2112 type III effector protein YP_003004347.1 KEGG: eca:ECA2113 putative avirulence protein YP_003004348.1 PFAM: DspFAvrF family protein; Tir chaperone family protein; KEGG: eca:ECA2114 putative avirulence protein YP_003004349.1 KEGG: pae:PA4285 exodeoxyribonuclease V gamma chain; TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V RecC subunit YP_003004350.1 KEGG: pen:PSEEN0692 exonuclease V, beta subunit; TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase YP_003004351.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: bvi:Bcep1808_6232 DNA helicase/exodeoxyribonuclease V, alpha subunit YP_003004352.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_003004353.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bch:Bcen2424_6908 NADH:flavin oxidoreductase/NADH oxidase YP_003004354.1 KEGG: swi:Swit_3359 hypothetical protein YP_003004355.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: asa:ASA_0430 LysR family transcriptional regulator YP_003004356.1 KEGG: aha:AHA_3221 TPR repeat-containing protein YP_003004357.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: asa:ASA_1093 short chain dehydrogenase YP_003004358.1 KEGG: asa:ASA_1094 hypothetical protein YP_003004359.1 PFAM: AMP-dependent synthetase and ligase; KEGG: aha:AHA_3218 long-chain acyl-CoA synthetases YP_003004360.1 KEGG: aha:AHA_3217 thermostable hemolysin YP_003004361.1 PFAM: Haemin-degrading family protein; KEGG: yps:YPTB0339 hemin degradation/transport protein HmuS YP_003004362.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: eca:ECA0785 two component system response regulator YP_003004363.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA0786 two component system sensor kinase YP_003004364.1 PFAM: Flp/Fap pilin component; KEGG: mmw:Mmwyl1_0303 Flp/Fap pilin component YP_003004365.1 PFAM: peptidase A24A prepilin type IV; KEGG: eca:ECA0787 hypothetical protein YP_003004366.1 TIGRFAM: Flp pilus assembly protein CpaB; PFAM: SAF domain protein; KEGG: eca:ECA0788 hypothetical protein YP_003004367.1 PFAM: type II and III secretion system protein; KEGG: eca:ECA0789 hypothetical protein YP_003004368.1 TIGRFAM: pilus (Caulobacter type) biogenesis lipoprotein CpaD; KEGG: eca:ECA0790 putative lipoprotein YP_003004369.1 KEGG: eca:ECA0791 hypothetical protein YP_003004370.1 PFAM: type II secretion system protein E; KEGG: eca:ECA0792 putative type IV pilus protein YP_003004371.1 PFAM: type II secretion system protein; KEGG: eca:ECA0793 putative type IV pilus protein YP_003004372.1 PFAM: type II secretion system protein; KEGG: eca:ECA0794 putative type IV pilus protein YP_003004373.1 PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein; KEGG: eca:ECA0795 hypothetical protein YP_003004374.1 KEGG: eca:ECA0796 hypothetical protein YP_003004375.1 KEGG: eca:ECA0797 hypothetical protein YP_003004376.1 KEGG: eca:ECA0798 hypothetical protein YP_003004377.1 PFAM: Ig family protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: eca:ECA0799 putative outer membrane protein YP_003004378.1 KEGG: eca:ECA0800 hypothetical protein YP_003004379.1 PFAM: secretion protein HlyD family protein; KEGG: eca:ECA0801 hypothetical protein YP_003004380.1 KEGG: eca:ECA0802 hypothetical protein YP_003004381.1 KEGG: eca:ECA0803 hypothetical protein YP_003004382.1 PFAM: regulatory protein TetR; KEGG: sbp:Sbal223_2172 transcriptional regulator, TetR family YP_003004383.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: sbp:Sbal223_2173 NADH:flavin oxidoreductase/NADH oxidase YP_003004384.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbp:Sbal223_2174 short-chain dehydrogenase/reductase SDR YP_003004385.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: sbp:Sbal223_2175 short-chain dehydrogenase/reductase SDR YP_003004386.1 KEGG: sbp:Sbal223_2176 hypothetical protein YP_003004387.1 PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: bac:BamMC406_5268 alcohol dehydrogenase YP_003004388.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_003004389.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_003004390.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_003004391.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: scl:sce5647 LysR family transcriptional regulator YP_003004392.1 PFAM: ThiJ/PfpI domain protein; KEGG: xfm:Xfasm12_0479 NonF-related protein YP_003004393.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_003004394.1 KEGG: eca:ECA2187 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein YP_003004395.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_003004396.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_003004397.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_003004398.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: eca:ECA2191 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_003004400.1 KEGG: eca:ECA2193 putative transcriptional regulator YP_003004401.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_003004402.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA2203 hypothetical protein YP_003004403.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_003004404.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_003004405.1 with UspC and UspD is involved in resistance to UV irradiation YP_003004406.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_003004407.1 KEGG: eca:ECA2208 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylguanine DNA methyltransferase ribonuclease domain protein YP_003004408.1 PFAM: domain of unknown function DUF1745; chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: esa:ESA_00603 hypothetical protein YP_003004409.1 KEGG: eca:ECA2172 hypothetical protein YP_003004410.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0080 methyl-accepting chemotaxis protein YP_003004411.1 PFAM: putative sugar-specific permease SgaT/UlaA; KEGG: ent:Ent638_1785 putative sugar-specific permease, SgaT/UlaA YP_003004412.1 PFAM: Phenolic acid decarboxylase; KEGG: kpe:KPK_0265 phenolic acid decarboxylase YP_003004413.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0068 LysR family transcriptional regulator YP_003004414.1 PFAM: ROK family protein; KEGG: atc:AGR_L_609 hypothetical protein YP_003004415.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypb:YPTS_2074 ABC transporter related YP_003004416.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: msu:MS0583 PotB protein YP_003004417.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: asu:Asuc_1526 binding-protein-dependent transport systems inner membrane component YP_003004418.1 KEGG: ypi:YpsIP31758_2059 putative spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein YP_003004419.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: psp:PSPPH_4534 glycerophosphodiester phosphodiesterase YP_003004420.1 PFAM: inositol monophosphatase; KEGG: pst:PSPTO_0659 inositol monophosphatase family protein YP_003004421.1 KEGG: rec:RHECIAT_PC0000667 hypothetical protein YP_003004422.1 KEGG: ret:RHE_PF00443 putative dehydrogenase large subunit protein YP_003004423.1 KEGG: rec:RHECIAT_PC0000668 hypothetical protein YP_003004424.1 KEGG: eca:ECA2217 putative virulence factor YP_003004425.1 PFAM: virulence protein SrfB; KEGG: eca:ECA2218 putative virulence effector protein YP_003004426.1 KEGG: eca:ECA2219 putative virulence effector protein YP_003004428.1 PFAM: NmrA family protein; TrkA-N domain protein; KEGG: yen:YE1738 hypothetical protein YP_003004429.1 PFAM: metalloprotease inhibitor I38; KEGG: eca:ECA2784 protease inhibitor YP_003004430.1 KEGG: eca:ECA2783 protease secretion ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase YP_003004431.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA2782 protease secretion protein YP_003004432.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: eca:ECA2781 protease secretion protein YP_003004433.1 KEGG: eca:ECA2785 metalloprotease; PFAM: Peptidase M10 serralysin ; Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase YP_003004434.1 KEGG: eca:ECA2785 metalloprotease; PFAM: Peptidase M10 serralysin ; Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase YP_003004435.1 KEGG: eca:ECA2785 metalloprotease; PFAM: Peptidase M10 serralysin ; Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase YP_003004436.1 PFAM: regulatory protein TetR; KEGG: eta:ETA_17340 TetR-family transcriptional regulator YP_003004437.1 KEGG: eca:ECA1567 putative lipoprotein YP_003004438.1 PFAM: Rare lipoprotein A; KEGG: eca:ECA2220 putative cellulase YP_003004439.1 TIGRFAM: C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: cko:CKO_01466 potassium-tellurite ethidium and proflavin transporter YP_003004440.1 PFAM: acyltransferase 3; KEGG: rso:RSc3292 hypothetical protein YP_003004441.1 PFAM: protein of unknown function DUF419; KEGG: pst:PSPTO_3016 hypothetical protein YP_003004442.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2922 LysR family transcriptional regulator YP_003004443.1 KEGG: eca:ECA1476 hypothetical protein YP_003004444.1 PFAM: Integrase catalytic region; KEGG: kpe:KPK_B0045 transposase YP_003004445.1 KEGG: shm:Shewmr7_1024 hypothetical protein YP_003004447.1 KEGG: spe:Spro_4949 helix-turn-helix domain-containing protein YP_003004448.1 PFAM: helix-turn-helix HxlR type; KEGG: gbe:GbCGDNIH1_1161 transcriptional regulator, MarR family YP_003004449.1 PFAM: NmrA family protein; KEGG: bph:Bphy_6079 NmrA family protein YP_003004450.1 TIGRFAM: mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; sucrose-6F-phosphate phosphohydrolase; KEGG: spe:Spro_2341 mannosyl-3-phosphoglycerate phosphatase YP_003004451.1 KEGG: eca:ECA2249 hypothetical protein YP_003004452.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_003004453.1 KEGG: eca:ECA2253 hypothetical protein YP_003004454.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_003004455.1 PFAM: ROK family protein; KEGG: eca:ECA2258 transcriptional regulator YP_003004456.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2259 LysR family transcriptional regulator YP_003004457.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2260 putative transporter YP_003004458.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_003004459.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_003004460.1 KEGG: eca:ECA2263 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I YP_003004461.1 PFAM: protein of unknown function DUF945; KEGG: eca:ECA2264 hypothetical protein YP_003004462.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: ccs:CCNA_03270 transcriptional regulator, AsnC family YP_003004463.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mmw:Mmwyl1_4055 hypothetical protein YP_003004464.1 KEGG: eca:ECA2266 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase YP_003004465.1 PFAM: Calcium/calmodulin dependent protein kinase II association-domain protein; KEGG: eca:ECA2267 hypothetical protein YP_003004466.1 PFAM: Bile acid:sodium symporter; KEGG: eca:ECA2268 putative sodium bile acid symporter YP_003004467.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; Oxidoreductase domain; KEGG: eca:ECA2269 putative oxidoreductase YP_003004468.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_003004469.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_003004470.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_003004471.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA2273 L-arabinose-binding periplasmic protein YP_003004472.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_003004473.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_003004474.1 PFAM: Rhamnogalacturonate lyase; KEGG: eca:ECA0804 rhamnogalacturonate lyase YP_003004475.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_003004476.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: yen:YE1994 Na(+)-translocating NADH-quinone reductase subunit E YP_003004477.1 TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; PFAM: Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2277 electron transport complex protein RnfB YP_003004478.1 TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2278 electron transport complex protein RnfC YP_003004479.1 TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; KEGG: spe:Spro_2237 electron transport complex protein RnfD YP_003004480.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_003004481.1 TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: eca:ECA2281 SoxR-reducing system protein RsxE YP_003004482.1 KEGG: stm:STM1453 endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop YP_003004483.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2284 transcriptional regulator CysB YP_003004484.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_003004485.1 KEGG: eca:ECA2287 hypothetical protein YP_003004486.1 KEGG: plu:plu4748 hypothetical protein YP_003004487.1 KEGG: eca:ECA0368 hypothetical protein YP_003004488.1 SohB; periplasmic protein; member of the peptidase S49 family YP_003004489.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA2289 short chain dehydrogenase YP_003004490.1 KEGG: ypy:YPK_2038 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_003004491.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_003004492.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: eca:ECA2292 hypothetical protein YP_003004493.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: eca:ECA2293 putative phosphoesterase YP_003004494.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_003004495.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_003004496.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_003004497.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_003004498.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_003004499.1 TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; KEGG: spe:Spro_2672 tryptophan synthase, alpha subunit YP_003004501.1 PFAM: Oligogalacturonate-specific porin; KEGG: eca:ECA2302 putative oligogalacturonate-specific porin YP_003004502.1 receptor for colicin S4 YP_003004503.1 PFAM: protein of unknown function UPF0153; KEGG: kpe:KPK_3194 hypothetical protein YP_003004504.1 PFAM: protein of unknown function UPF0259; KEGG: eca:ECA2305 hypothetical protein YP_003004505.1 TIGRFAM: intracellular septation protein A; PFAM: Intracellular septation protein A; KEGG: spe:Spro_2677 intracellular septation protein A YP_003004506.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_003004507.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_003004508.1 PFAM: YCII-related; KEGG: eum:ECUMN_1550 putative enzyme YP_003004509.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2317 methyl-accepting chemotaxis protein YP_003004510.1 KEGG: ypi:YpsIP31758_1952 hypothetical protein YP_003004511.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_003004512.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_003004513.1 KEGG: eca:ECA2320 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_003004514.1 KEGG: spe:Spro_2698 oligopeptide transporter ATP-binding component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_003004515.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2322 oligopeptide transport system permease protein YP_003004516.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2323 oligopeptide transporter permease YP_003004517.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2324 periplasmic oligopeptide-binding protein YP_003004518.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ypi:YpsIP31758_1962 hypothetical protein YP_003004519.1 PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: eca:ECA2326 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_003004520.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_003004521.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: spe:Spro_2706 global DNA-binding transcriptional dual regulator H-NS YP_003004522.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_003004523.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA2330 response regulator of RpoS YP_003004524.1 PFAM: Patatin; KEGG: eca:ECA2331 hypothetical protein YP_003004525.1 PFAM: SEC-C motif domain protein; KEGG: eca:ECA2332 hypothetical protein YP_003004526.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_003004527.1 PFAM: protein of unknown function UPF0126; KEGG: eca:ECA2334 hypothetical protein YP_003004528.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: spe:Spro_2715 exonuclease III YP_003004529.1 PFAM: protein of unknown function DUF1496; KEGG: eca:ECA2336 hypothetical protein YP_003004530.1 decatenates replicating daughter chromosomes YP_003004531.1 PFAM: nitroreductase; KEGG: eca:ECA2338 hypothetical protein YP_003004532.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: eca:ECA2339 protease 4 YP_003004533.1 converts asparagine to aspartate and ammonia YP_003004534.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_003004535.1 PFAM: protein of unknown function DUF1315; KEGG: eca:ECA2342 hypothetical protein YP_003004536.1 KEGG: ypi:YpsIP31758_1986 methionine sulfoxide reductase B; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B YP_003004537.1 KEGG: yen:YE2265 glyceraldehyde 3-phosphate dehydrogenase A; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_003004538.1 PFAM: Aldose 1-epimerase; KEGG: eca:ECA2345 putative aldose 1-epimerase YP_003004539.1 PFAM: aldo/keto reductase; KEGG: eca:ECA2346 putative aldo/keto reductase YP_003004540.1 PFAM: MltA-interacting MipA family protein; KEGG: eca:ECA2347 MltA-interacting protein YP_003004541.1 PFAM: PrkA AAA domain protein; PrkA serine kinase; SMART: PrkA AAA domain protein; KEGG: eca:ECA2348 hypothetical protein YP_003004542.1 PFAM: protein of unknown function DUF444; KEGG: eca:ECA2349 hypothetical protein YP_003004543.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1552 ABC transporter ATP-binding protein YP_003004544.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_2740 ABC transporter-related protein YP_003004545.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1549 putative ABC transporter substrate-binding protein YP_003004546.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1548 putative transport system membrane protein YP_003004547.1 PFAM: Transglycosylase-associated protein; KEGG: eca:ECA2044 hypothetical protein YP_003004548.1 PFAM: DNA/RNA non-specific endonuclease; SMART: DNA/RNA non-specific endonuclease; KEGG: ppd:Ppro_2565 DNA/RNA non-specific endonuclease YP_003004549.1 KEGG: yps:YPTB1832 hypothetical protein YP_003004550.1 KEGG: aca:ACP_1655 hypothetical protein YP_003004551.1 PFAM: protein of unknown function DUF1364; KEGG: kpe:KPK_2854 hypothetical protein YP_003004553.1 KEGG: sml:Smlt3111 hypothetical protein YP_003004554.1 PFAM: IS1 transposase; KEGG: sdy:SDY_2013 iso-IS1 ORF2 YP_003004556.1 KEGG: eca:ECA2472 hypothetical protein YP_003004558.1 PFAM: Ferritin Dps family protein; KEGG: eca:ECA2473 ferritin YP_003004559.1 PFAM: copper resistance D domain protein; KEGG: seh:SeHA_C2088 copper resistance protein D YP_003004560.1 PFAM: copper resistance protein CopC; KEGG: sgl:SG1276 putative copper resistance protein YP_003004561.1 PFAM: DNA polymerase II beta subunit; KEGG: spe:Spro_1941 DNA polymerase III subunit theta YP_003004562.1 KEGG: ypg:YpAngola_A1627 hypothetical protein YP_003004563.1 PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: eca:ECA2476 protease II YP_003004564.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_003004565.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_003004566.1 KEGG: eca:ECA2479 glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase YP_003004567.1 Represses the expression of the zwf, eda, glp and gap YP_003004568.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003004569.1 KEGG: hypothetical protein YP_003004570.1 similar to GK23239 gene product from transcript GK23239-RA; KEGG: GK23239 gene product from transcript GK23239-RA YP_003004571.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_003004572.1 PFAM: Peptidase M23; Peptidoglycan-binding LysM; Opacity-associated protein A; Opacity-associated protein A domain protein; SMART: Peptidoglycan-binding LysM; KEGG: eca:ECA2483 hypothetical protein YP_003004573.1 involved in transport of zinc(II) with ZnuA and C YP_003004574.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2485 high-affinity zinc transporter ATPase YP_003004575.1 involved in transport of zinc(II) with ZnuA and C YP_003004576.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_003004577.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_003004578.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003004579.1 TIGRFAM: high-affinity nickel-transporter; PFAM: high-affinity nickel-transporter; KEGG: esa:ESA_02056 hypothetical protein YP_003004580.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_003004581.1 PFAM: protein of unknown function DUF28; KEGG: eca:ECA2494 hypothetical protein YP_003004582.1 converts dATP to dAMP and pyrophosphate YP_003004583.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_003004584.1 PFAM: protein of unknown function DUF72; KEGG: spe:Spro_2784 hypothetical protein YP_003004585.1 KEGG: eca:ECA2510 hypothetical protein YP_003004586.1 TIGRFAM: methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: spe:Spro_2786 putative methyltransferase YP_003004587.1 TIGRFAM: methyltransferase; PFAM: methyltransferase putative; KEGG: eca:ECA2512 hypothetical protein YP_003004589.1 PFAM: CutC family protein; KEGG: eca:ECA2518 copper homeostasis protein CutC YP_003004590.1 PFAM: protein of unknown function DUF991; KEGG: eca:ECA2519 hypothetical protein YP_003004591.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_003004592.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: rme:Rmet_0160 methyl-accepting chemotaxis sensory transducer YP_003004593.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: eca:ECA2521 putative virulence factor YP_003004594.1 PFAM: oxidoreductase domain protein; KEGG: eca:ECA2522 putative virulence factor YP_003004595.1 PFAM: protein of unknown function DUF480; KEGG: efe:EFER_1862 hypothetical protein YP_003004596.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2524 ribosomal-protein-S5-alanine N-acetyltransferase YP_003004597.1 Confers resistance to norfloxacin and enoxacin YP_003004598.1 TIGRFAM: glutaredoxin, GrxB family; PFAM: glutaredoxin 2 domain protein; Glutathione S-transferase domain; KEGG: spe:Spro_2798 glutaredoxin 2 YP_003004599.1 PFAM: protein of unknown function DUF1439; KEGG: eca:ECA2527 hypothetical protein YP_003004600.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein YP_003004601.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ypg:YpAngola_A2446 putative hydrolase YP_003004602.1 PFAM: regulatory protein TetR; KEGG: rce:RC1_2390 transcriptional regulator, TetR family protein YP_003004603.1 PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; KEGG: hypothetical protein YP_003004604.1 PFAM: AraC-type transcriptional regulator domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: lch:Lcho_4307 AraC family transcriptional regulator YP_003004605.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bur:Bcep18194_C7286 NADH-flavin oxidoreductase/NADH oxidase YP_003004606.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: dac:Daci_4383 short chain dehydrogenase YP_003004607.1 KEGG: sbm:Shew185_3355 hypothetical protein YP_003004609.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: bur:Bcep18194_A3790 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_003004610.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_A3789 LysR family transcriptional regulator YP_003004611.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein GntR HTH; SMART: regulatory protein DeoR; KEGG: spe:Spro_2259 DeoR family transcriptional regulator YP_003004612.1 PFAM: NUDIX hydrolase; KEGG: spe:Spro_2260 NUDIX hydrolase YP_003004613.1 PFAM: ribonuclease T2; KEGG: pfl:PFL_3322 ribonuclease T2 family protein, putative YP_003004614.1 PFAM: NUDIX hydrolase; KEGG: hypothetical protein YP_003004615.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bbt:BBta_2707 putative oxidoreductase YP_003004616.1 PFAM: helix-turn-helix HxlR type; KEGG: bbt:BBta_2706 putative transcriptional regulator YP_003004617.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_003004618.1 PFAM: FAD dependent oxidoreductase; KEGG: eca:ECA0052 hypothetical protein YP_003004620.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_003004621.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_003004622.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_003004623.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_003004624.1 PFAM: protein of unknown function DUF218; KEGG: eca:ECA2551 hypothetical protein YP_003004625.1 KEGG: eca:ECA2552 hypothetical protein YP_003004626.1 KEGG: eca:ECA2553 pectate lyase YP_003004627.1 KEGG: eca:ECA2554 3-deoxy-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase YP_003004628.1 PFAM: protein of unknown function DUF343; KEGG: eca:ECA2555 hypothetical protein YP_003004629.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_003004630.1 involved in the transport of lipid A across the inner membrane YP_003004631.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase domain protein; KEGG: eca:ECA2558 hypothetical protein YP_003004633.1 PFAM: protein of unknown function DUF496; KEGG: eca:ECA2560 hypothetical protein YP_003004634.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_003004635.1 PFAM: amino acid permease-associated region; KEGG: eta:ETA_13600 putative amino acid permease YP_003004637.1 PFAM: YcgR family protein; type IV pilus assembly PilZ; KEGG: eca:ECA2568 hypothetical protein YP_003004638.1 KEGG: eca:ECA2569 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; PFAM: triphosphoribosyl-dephospho-CoA protein YP_003004639.1 KEGG: eca:ECA2570 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; TIGRFAM: holo-ACP synthase CitX; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase YP_003004640.1 KEGG: eca:ECA2571 citrate lyase alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit YP_003004641.1 KEGG: eca:ECA2572 citrate lyase beta chain; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase YP_003004642.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_003004643.1 KEGG: eca:ECA2574 [citrate [pro-3s]-lyase] ligase; TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: Citrate lyase ligase domain protein; GCN5-related N-acetyltransferase; cytidylyltransferase; SMART: Citrate lyase ligase domain protein YP_003004644.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: eca:ECA2575 putative fumarylacetoacetate hydrolase YP_003004645.1 PFAM: Citrate carrier protein; KEGG: eca:ECA2576 citrate/acetate antiporter YP_003004646.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; KEGG: eca:ECA2577 two-component sensor kinase YP_003004647.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA2578 two-component response regulator YP_003004648.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2580 putative methyl-accepting chemotaxis citrate transducer YP_003004649.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: yen:YE2764 hypothetical protein YP_003004650.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_003004651.1 KEGG: eca:ECA2583 histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: histidinol dehydrogenase YP_003004652.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_003004653.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_003004654.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_003004655.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_003004656.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_003004657.1 TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-AMP cyclohydrolase; KEGG: eca:ECA2589 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_003004658.1 KEGG: plu:plu3101 hypothetical protein YP_003004659.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_003004660.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_003004661.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_003004662.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_003004663.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_003004664.1 PFAM: protein of unknown function DUF181; KEGG: eca:ECA2595 hypothetical protein YP_003004665.1 TIGRFAM: formate/nitrite transporter; PFAM: formate/nitrite transporter; KEGG: eca:ECA2596 formate transporter YP_003004666.1 KEGG: eca:ECA2597 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_003004667.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_003004668.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: eca:ECA2642 LysR family transcriptional regulator YP_003004669.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2643 MFS family transporter YP_003004670.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pst:PSPTO_2447 LysR family transcriptional regulator YP_003004671.1 PFAM: beta-lactamase domain protein; KEGG: bpm:BURPS1710b_3190 metallo-beta-lactamase family protein YP_003004672.1 KEGG: rpi:Rpic_1321 hypothetical protein YP_003004673.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: spe:Spro_1690 twin-argninine leader-binding protein DmsD YP_003004674.1 KEGG: eca:ECA2644 seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like YP_003004675.1 PFAM: beta-lactamase domain protein; KEGG: rec:RHECIAT_CH0003332 putative alkyl sulfatase beta-lactamase family protein YP_003004676.1 PFAM: transposase mutator type; KEGG: yps:YPTB0777 putative transposase-like protein YP_003004677.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: dac:Daci_5359 recombination factor protein RarA YP_003004678.1 KEGG: eca:ECA2645 recombination factor protein RarA YP_003004679.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_003004680.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: eca:ECA2647 cell division protein YP_003004681.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_003004682.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA2649 thioredoxin reductase YP_003004683.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_003004684.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_003004685.1 KEGG: spe:Spro_1676 leucyl/phenylalanyl-tRNA--protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA/protein transferase; PFAM: leucyl/phenylalanyl-tRNA--protein transferase YP_003004686.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_003004687.1 KEGG: eca:ECA2656 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase YP_003004688.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: eca:ECA2657 ATP-dependent Clp protease adaptor protein ClpS YP_003004689.1 KEGG: see:SNSL254_A0978 cold shock domain protein CspD; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_003004690.1 KEGG: eca:ECA2660 hypothetical protein YP_003004691.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_003004692.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: eca:ECA2663 HCP oxidoreductase, NADH-dependent YP_003004693.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: eca:ECA2664 hypothetical protein YP_003004694.1 KEGG: eca:ECA2665 putative N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2 YP_003004695.1 PFAM: protein of unknown function DUF74; KEGG: eca:ECA2666 hypothetical protein YP_003004696.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2667 arginine transporter ATP-binding subunit YP_003004697.1 KEGG: eca:ECA2668 arginine-binding periplasmic protein 1; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor YP_003004698.1 with ArtPMJI transports arginine across the inner membrane YP_003004699.1 with ArtPQJI acts to transport arginine across the inner membrane YP_003004700.1 KEGG: eca:ECA2671 arginine-binding periplasmic protein 2; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor YP_003004701.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_003004702.1 KEGG: eca:ECA2673 hypothetical protein YP_003004703.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2674 putrescine ABC transporter membrane protein YP_003004704.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2675 putrescine ABC transporter membrane protein YP_003004705.1 part of the PotFGHI ATP-dependent putrescine transporter YP_003004706.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_2645 putrescine transporter subunit: periplasmic-binding component of ABC superfamily YP_003004707.1 KEGG: eca:ECA2678 hypothetical protein YP_003004708.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: eca:ECA2679 ribosomal protein S6 modification protein YP_003004709.1 PFAM: nitroreductase; KEGG: esa:ESA_02486 nitroreductase A YP_003004710.1 TIGRFAM: glutaredoxin, GrxA family; PFAM: glutaredoxin; KEGG: spe:Spro_1641 glutaredoxin 1 YP_003004711.1 KEGG: eca:ECA2682 hypothetical protein YP_003004713.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; KEGG: eca:ECA2683 hypothetical protein YP_003004714.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA2685 DNA-binding transcriptional repressor DeoR YP_003004715.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: eca:ECA2686 penicillin-binding protein 6 YP_003004716.1 PFAM: alpha/beta hydrolase fold; KEGG: bpd:BURPS668_A1921 rhamnosyltransferase 1 subunit A YP_003004717.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2687 ABC transporter integral membrane protein YP_003004718.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2688 ABC transporter ATP-binding protein YP_003004719.1 PFAM: NLPA lipoprotein; KEGG: eca:ECA2689 putative lipoprotein YP_003004720.1 PFAM: Glutathione S-transferase domain; KEGG: eca:ECA2690 putative glutathione S-transferase YP_003004721.1 PFAM: glucose sorbosone dehydrogenase; KEGG: eca:ECA2691 hypothetical protein YP_003004722.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_003004723.1 PFAM: protein of unknown function DUF218; KEGG: eca:ECA2709 hypothetical protein YP_003004724.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: eca:ECA2710 hypothetical protein YP_003004725.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_003004726.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA1509 methyl-accepting chemotaxis protein YP_003004727.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2712 putative methyl-accepting chemotaxis protein YP_003004728.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA2712 putative methyl-accepting chemotaxis protein YP_003004729.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA2712 putative methyl-accepting chemotaxis protein YP_003004730.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2713 LysR family transcriptional regulator YP_003004731.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: spe:Spro_1557 S-(hydroxymethyl)glutathione dehydrogenase YP_003004732.1 KEGG: spe:Spro_1556 S-formylglutathione hydrolase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_003004733.1 KEGG: eca:ECA2717 hypothetical protein YP_003004734.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_003004735.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2719 ABC transporter, ATP-binding protein YP_003004736.1 PFAM: inner-membrane translocator; KEGG: eca:ECA2720 ABC transporter, permease protein YP_003004737.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_3194 sugar efflux transporter YP_003004738.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA2723 lysine transporter YP_003004739.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2724 putative DNA-binding transcriptional regulator YP_003004740.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA2725 hypothetical protein YP_003004741.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_003004742.1 KEGG: she:Shewmr4_1705 hypothetical protein YP_003004743.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003004744.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003004745.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_003004746.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_003004747.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2730 sugar efflux transporter YP_003004748.1 PFAM: protein of unknown function UPF0153; KEGG: eca:ECA2731 hypothetical protein YP_003004749.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_003004750.1 PFAM: cobalamin synthesis protein P47K; KEGG: eca:ECA2733 hypothetical protein YP_003004751.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_003004752.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2736 putative ABC transporter, periplasmic binding protein YP_003004753.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2737 putative binding-protein-dependent transporter YP_003004754.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2738 ABC transporter permease YP_003004755.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2739 putative ABC-transporter, ATP-binding protein YP_003004756.1 KEGG: eca:ECA2740 hypothetical protein YP_003004757.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_003004758.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_003004759.1 KEGG: cko:CKO_01041 hypothetical protein YP_003004760.1 PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; KEGG: eca:ECA2744 putative helicase YP_003004761.1 PFAM: ribosomal protein L25; KEGG: eca:ECA2745 50S ribosomal protein L25 YP_003004762.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2430 hypothetical protein YP_003004763.1 PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: cko:CKO_00419 hypothetical protein YP_003004764.1 KEGG: eta:ETA_11160 putative sensor protein; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein YP_003004765.1 PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein NdpA YP_003004766.1 PFAM: protein of unknown function DUF1414; KEGG: spe:Spro_3256 hypothetical protein YP_003004767.1 PFAM: sulfatase; KEGG: eca:ECA2749 putative sulphatase YP_003004768.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: psb:Psyr_4923 regulatory protein, LysR:LysR, substrate-binding YP_003004769.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ppf:Pput_1853 short chain dehydrogenase YP_003004770.1 PFAM: Glutathione S-transferase domain; KEGG: ara:Arad_7543 glutathione S-transferase protein YP_003004771.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: eca:ECA2757 hypothetical protein YP_003004772.1 PFAM: plasmid stabilization system; KEGG: eca:ECA2758 hypothetical protein YP_003004773.1 PFAM: glutathione peroxidase; KEGG: kpn:KPN_01190 putative glutathione peroxidase YP_003004774.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: efe:EFER_2615 hypothetical protein YP_003004777.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: bcm:Bcenmc03_2495 short-chain dehydrogenase/reductase SDR YP_003004778.1 PFAM: regulatory protein TetR; KEGG: bcm:Bcenmc03_2496 TetR family transcriptional regulator YP_003004780.1 KEGG: ecr:ECIAI1_3650 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_003004781.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: hypothetical protein LOC754318 YP_003004782.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: yen:YE3472 DNA-binding transcriptional repressor ArsR YP_003004783.1 PFAM: protein of unknown function DUF1304; KEGG: kpn:KPN_01507 hypothetical protein YP_003004786.1 KEGG: hin:HI1492 hypothetical protein YP_003004787.1 PFAM: GlpM family protein; KEGG: eca:ECA0108 hypothetical protein YP_003004788.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_003004789.1 PFAM: secretion protein HlyD family protein; KEGG: plu:plu2645 hypothetical protein YP_003004790.1 PFAM: outer membrane efflux protein; KEGG: plu:plu2646 hypothetical protein YP_003004791.1 PFAM: protein of unknown function DUF214; KEGG: plu:plu2647 hypothetical protein YP_003004792.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pfl:PFL_2947 ABC transporter, ATP-binding protein YP_003004794.1 PFAM: heat shock protein Hsp20; KEGG: set:SEN1800 putative heat shock protein YP_003004795.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: bmj:BMULJ_02890 hypothetical protein YP_003004796.1 KEGG: pap:PSPA7_0599 biotin-dependent carboxylase domain-containing protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2 YP_003004797.1 PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: ppg:PputGB1_2861 allophanate hydrolase subunit 1 YP_003004798.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_003004799.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: vei:Veis_4578 hypothetical protein YP_003004800.1 PFAM: LamB/YcsF family protein; KEGG: pae:PA0492 hypothetical protein YP_003004801.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: psp:PSPPH_2444 LysR family transcriptional regulator YP_003004802.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2763 transport protein YP_003004803.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmn:BMA10247_0906 MarR family transcriptional regulator YP_003004804.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_003004805.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA2765 threonine and homoserine efflux system YP_003004806.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_003004807.1 similar to periplasmic-binding component of ABC transporters YP_003004808.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_003004809.1 similar to ATP-binding component of ABC transporters YP_003004810.1 PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: afw:Anae109_2327 cell surface receptor IPT/TIG domain-containing protein YP_003004811.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: eta:ETA_04650 putative phosphatase YP_003004812.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: eca:ECA2771 putative peptidase YP_003004813.1 PFAM: Glycosyl transferase, family 3-like; KEGG: eca:ECA2772 hypothetical protein YP_003004814.1 helicase involved in DNA repair and perhaps also replication YP_003004815.1 KEGG: ecz:ECS88_2271 hypothetical protein YP_003004816.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: eca:ECA2790 periplasmic beta-glucosidase YP_003004817.1 PFAM: aminotransferase class-III; KEGG: bpy:Bphyt_0048 aminotransferase class-III YP_003004818.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: eta:ETA_34310 transcriptional regulator, DeoR family YP_003004819.1 PFAM: Glutathione S-transferase domain; KEGG: eca:ECA2791 putative glutathione S-transferase YP_003004820.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_003004821.1 TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: eca:ECA2795 adenylate cyclase YP_003004822.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pae:PA1129 fosfomycin resistance protein YP_003004823.1 PFAM: dihydrouridine synthase DuS; KEGG: kpe:KPK_1587 tRNA-dihydrouridine synthase C YP_003004824.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2801 periplasmic dipeptide transport protein YP_003004825.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_003004826.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: spe:Spro_2337 AraC family transcriptional regulator YP_003004827.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: swi:Swit_0727 hypothetical protein YP_003004828.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: kpn:KPN_01938 putative transmembrane protein YP_003004829.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; KEGG: eca:ECA2805 ATP-dependent RNA helicase RhlE YP_003004830.1 PFAM: secretion protein HlyD family protein; KEGG: spe:Spro_1329 hypothetical protein YP_003004831.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_1328 ABC transporter-related protein YP_003004832.1 PFAM: ABC-2 type transporter; KEGG: yen:YE2893 hypothetical protein YP_003004833.1 PFAM: ABC-2 type transporter; KEGG: spe:Spro_1326 ABC-2 type transporter YP_003004834.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: kpn:KPN_00818 putative DNase YP_003004835.1 PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; KEGG: esa:ESA_02556 cardiolipin synthase 2 YP_003004836.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sgl:SG1481 transposase YP_003004837.1 PFAM: protein of unknown function UPF0005; KEGG: eca:ECA2812 hypothetical protein YP_003004838.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: spe:Spro_2536 ABC transporter-related protein YP_003004839.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_2535 binding-protein-dependent transport systems inner membrane component YP_003004840.1 PFAM: extracellular solute-binding protein family 1; KEGG: spe:Spro_2534 extracellular solute-binding protein YP_003004841.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_003004842.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit YP_003004843.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: eca:ECA2815 molybdenum cofactor biosynthesis protein C YP_003004844.1 TIGRFAM: molybdenum cofactor biosynthesis protein B; molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: eca:ECA2816 molybdenum cofactor biosynthesis protein B YP_003004845.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_003004846.1 KEGG: ent:Ent638_2133 hypothetical protein YP_003004847.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: eta:ETA_23730 ubiquinol oxidase subunit II, cyanide insensitive YP_003004848.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: eta:ETA_23720 ubiquinol oxidase subunit I, cyanide insensitive YP_003004852.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: eca:ECA2818 hypothetical protein YP_003004853.1 KEGG: eca:ECA3982 hypothetical protein YP_003004854.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_003004855.1 KEGG: eca:ECA2822 dithiobiotin synthetase; TIGRFAM: dethiobiotin synthase; PFAM: Cobyrinic acid ac-diamide synthase YP_003004856.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: eca:ECA2823 biotin synthesis protein YP_003004857.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_003004858.1 KEGG: eca:ECA2825 biotin synthase; TIGRFAM: biotin synthase; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_003004859.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_003004860.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: avi:Avi_0107 beta-glucosidase protein YP_003004861.1 PFAM: LrgA family protein; KEGG: eca:ECA2828 hypothetical protein YP_003004862.1 PFAM: LrgB family protein; KEGG: eca:ECA2829 hypothetical protein YP_003004863.1 KEGG: bph:Bphy_0250 hypothetical protein YP_003004864.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_003004865.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_003004866.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: eca:ECA2836 molybdopterin biosynthesis protein MoeA YP_003004867.1 TIGRFAM: molybdopterin synthase sulfurylase MoeB; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA2837 molybdopterin biosynthesis protein MoeB YP_003004868.1 PFAM: thioesterase superfamily protein; KEGG: pmr:PMI1691 thioesterase superfamilyl protein YP_003004869.1 PFAM: glycosyl transferase family 2; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: esa:ESA_04142 hypothetical protein YP_003004870.1 PFAM: flavodoxin/nitric oxide synthase; KEGG: elf:LF82_p421 hypothetical protein YP_003004871.1 PFAM: protein of unknown function UPF0057; KEGG: kpe:KPK_2957 hypothetical protein YP_003004872.1 PFAM: coagulation factor 5/8 type domain protein; KEGG: eca:ECA1186 hypothetical protein YP_003004873.1 KEGG: ecs:ECs1979 hypothetical protein YP_003004874.1 PFAM: coagulation factor 5/8 type domain protein; KEGG: eca:ECA1185 hypothetical protein YP_003004875.1 KEGG: ecs:ECs1979 hypothetical protein YP_003004876.1 PFAM: protein of unknown function DUF980; KEGG: yen:YE2610 hypothetical protein YP_003004877.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA2866 hypothetical protein YP_003004878.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 putative rhs accessory genetic element YP_003004879.1 PFAM: PAAR repeat-containing protein; KEGG: asa:ASA_3828 hypothetical protein YP_003004880.1 KEGG: ses:SARI_02589 hypothetical protein YP_003004881.1 KEGG: aha:AHA_2048 hypothetical protein YP_003004882.1 PFAM: Integrase catalytic region; KEGG: yps:YPTB1892 putative transposase YP_003004883.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypg:YpAngola_A2064 hypothetical protein YP_003004884.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; KEGG: eca:ECA4278 rhs-family protein YP_003004885.1 PFAM: pentapeptide repeat protein; KEGG: pae:PA2461 hypothetical protein YP_003004886.1 KEGG: eca:ECA3392 hypothetical protein YP_003004887.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu4299 hypothetical protein YP_003004888.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu4299 hypothetical protein YP_003004889.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns YP_003004890.1 KEGG: ecc:c0291 hypothetical protein YP_003004891.1 PFAM: protein of unknown function DUF606; KEGG: kpe:KPK_2583 hypothetical protein YP_003004892.1 PFAM: protein of unknown function DUF606; KEGG: ent:Ent638_1093 hypothetical protein YP_003004893.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_2581 transcriptional regulator, LysR family YP_003004894.1 KEGG: vco:VC0395_0742 transcriptional regulator, CopG family YP_003004895.1 PFAM: plasmid stabilization system; KEGG: rle:pRL110045 hypothetical protein YP_003004896.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003004897.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA4478 amino acid ABC transporter, ATP-binding protein YP_003004898.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4479 amino acid ABC transporter permease YP_003004899.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4480 amino acid ABC transporter permease YP_003004900.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA4481 short-chain dehydrogenase YP_003004901.1 KEGG: eca:ECA4482 hypothetical protein YP_003004902.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_003004903.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_003004904.1 PFAM: LamB/YcsF family protein; KEGG: eca:ECA4486 hypothetical protein YP_003004905.1 KEGG: eca:ECA4487 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2 YP_003004906.1 PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA4488 putative allophanate hydrolase subunit 1 YP_003004907.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4489 putative extracellular solute-binding protein YP_003004908.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA4490 hypothetical protein YP_003004909.1 KEGG: yen:YE2498 hypothetical protein YP_003004910.1 PFAM: AraC-type transcriptional regulator domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: rso:RSc0625 transcription regulator protein YP_003004911.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: abu:Abu_0784 iron-containing NADP-dependent alcohol dehydrogenase YP_003004912.1 PFAM: periplasmic solute binding protein; KEGG: spe:Spro_2133 periplasmic solute binding protein YP_003004913.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_2132 ABC transporter-related protein YP_003004914.1 PFAM: ABC-3 protein; transport system permease protein; KEGG: eca:ECA2394 chelated iron transport system membrane protein YP_003004915.1 PFAM: ABC-3 protein; KEGG: plu:plu2675 chelated iron transport system membrane protein YfeD-like protein YP_003004916.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: cko:CKO_04761 hypothetical protein YP_003004917.1 TIGRFAM: malonate decarboxylase, epsilon subunit; PFAM: Acyl transferase; KEGG: ent:Ent638_3772 acyl transferase domain-containing protein YP_003004918.1 Catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein YP_003004919.1 TIGRFAM: auxin efflux carrier; PFAM: Auxin Efflux Carrier; KEGG: ent:Ent638_3774 auxin efflux carrier YP_003004920.1 TIGRFAM: malonate decarboxylase, gamma subunit; PFAM: malonate decarboxylase gamma subunit; KEGG: cko:CKO_04765 hypothetical protein YP_003004921.1 The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A YP_003004922.1 TIGRFAM: malonate decarboxylase acyl carrier protein; PFAM: malonate decarboxylase delta subunit; KEGG: ent:Ent638_3777 malonate decarboxylase delta subunit YP_003004923.1 KEGG: ses:SARI_04158 hypothetical protein; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase MdcB; PFAM: triphosphoribosyl-dephospho-CoA protein YP_003004924.1 TIGRFAM: malonate decarboxylase, alpha subunit; KEGG: cko:CKO_04769 hypothetical protein YP_003004925.1 PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: eca:ECA1568 putative chemotaxis signal transduction protein YP_003004926.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: eca:ECA4420 ABC transporter ATP-binding protein YP_003004927.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4421 ABC transporter permease protein YP_003004928.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4422 ABC transporter permease protein YP_003004929.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: eca:ECA4423 putative nucleoside hydrolase YP_003004930.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: eca:ECA4424 putative nucleoside hydrolase protein YP_003004931.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4426 putative extracellular solute-binding protein YP_003004932.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA4427 LysR family transcriptional regulator YP_003004933.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: eca:ECA1560 CDP-diacylglycerol pyrophosphatase YP_003004934.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1559 LysR family transcriptional regulator YP_003004935.1 KEGG: eca:ECA1558 putative sulfate ester transporter, periplasmic binding component YP_003004936.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1557 putative sulfate ester transporter, permease component YP_003004937.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1556 putative sulfate ester transporter, ATP-binding component YP_003004938.1 PFAM: Thioredoxin domain; KEGG: eca:ECA1555 hypothetical protein YP_003004939.1 KEGG: mxa:MXAN_6237 hypothetical protein YP_003004940.1 similar to GE17595 gene product from transcript GE17595-RA; KEGG: GE17595 gene product from transcript GE17595-RA YP_003004941.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpe:KPK_2723 methionine uptake ABC transporter (MUT) family, permease protein YP_003004942.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_01653 D- and L-methionine ABC transporter ATP-binding protein YP_003004943.1 PFAM: NLPA lipoprotein; KEGG: esa:ESA_02817 hypothetical protein YP_003004944.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: yps:YPTB1347 putative iron/ascorbate oxidoreductase family protein YP_003004945.1 KEGG: spe:Spro_1006 putative periplasmic ligand-binding sensor protein YP_003004946.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA4305 LysR family transcriptional regulator YP_003004947.1 KEGG: eca:ECA4304 hypothetical protein YP_003004948.1 KEGG: eca:ECA4303 hypothetical protein YP_003004949.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA4302 TonB-dependent receptor YP_003004950.1 KEGG: eca:ECA4301 putative sulfate ester binding protein YP_003004951.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: eca:ECA4300 TonB protein YP_003004952.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: eca:ECA4299 putative biopolymer transport protein YP_003004953.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: eca:ECA4298 putative biopolymer transport protein YP_003004954.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4297 sulfate ester ABC transporter permease protein YP_003004955.1 KEGG: efe:EFER_1552 putative membrane-associated diguanylate cyclase (GGDEF domain); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003004956.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eta:ETA_13850 GCN5-related N-acetyltransferase YP_003004957.1 PFAM: FAD dependent oxidoreductase; KEGG: eta:ETA_13840 FAD dependent oxidoreductase YP_003004958.1 PFAM: peptidase C1A papain; KEGG: xft:PD0125 cysteine protease YP_003004959.1 PFAM: Integrase catalytic region; KEGG: kpe:KPK_B0045 transposase YP_003004960.1 KEGG: shm:Shewmr7_1024 hypothetical protein YP_003004962.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: plu:plu2192 hypothetical protein YP_003004963.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: hypothetical protein YP_003004964.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ajs:Ajs_4057 hypothetical protein YP_003004965.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_003004966.1 PFAM: glycoside hydrolase clan GH-D; KEGG: esa:ESA_03854 hypothetical protein YP_003004967.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: ent:Ent638_4078 LacI family transcription regulator YP_003004968.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_003004969.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: Formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA1407 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_003004970.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: eca:ECA1408 formate dehydrogenase, nitrate-inducible, major subunit YP_003004971.1 KEGG: bba:Bd0901 Zn-dependent hydrolase YP_003004972.1 PFAM: HicB family protein; KEGG: plu:plu0706 hypothetical protein YP_003004973.1 PFAM: Dimethylmenaquinone methyltransferase; KEGG: psp:PSPPH_2762 hypothetical protein YP_003004974.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: psp:PSPPH_2760 achromobactin transport ATP-binding protein CbrD YP_003004975.1 PFAM: transport system permease protein; KEGG: psb:Psyr_2592 transport system permease protein YP_003004976.1 PFAM: transport system permease protein; KEGG: sgl:SGP1_0037 achromobactin ABC transporter permease component CbrB YP_003004977.1 PFAM: periplasmic binding protein; KEGG: sgl:SGP1_0038 achromobactin ABC transporter periplasmic component CbrA YP_003004978.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003004979.1 PFAM: IucA/IucC family protein; KEGG: psb:Psyr_2589 IucA/IucC YP_003004980.1 PFAM: HpcH/HpaI aldolase; KEGG: psp:PSPPH_2755 achromobactin biosynthetic protein AcsB YP_003004981.1 PFAM: IucA/IucC family protein; KEGG: sgl:SGP1_0041 achromobactin biosynthetic and transport gene AcsC YP_003004982.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: psb:Psyr_2586 EmrB/QacA family drug resistance transporter YP_003004983.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: psb:Psyr_2585 Orn/DAP/Arg decarboxylase 2:Orn/DAP/Arg decarboxylase 2 YP_003004984.1 PFAM: IucA/IucC family protein; KEGG: psb:Psyr_2584 IucA/IucC YP_003004985.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA2810 TonB-dependent ferric achromobactin receptor YP_003004986.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_003004987.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_1413 phosphonate ABC transporter, inner membrane subunit YP_003004988.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_1412 phosphonate ABC transporter, inner membrane subunit YP_003004989.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate binding protein; phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: spe:Spro_1411 phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_003004990.1 KEGG: spe:Spro_1410 phosphonate ABC transporter, ATPase subunit; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_003004991.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rpi:Rpic_4851 transcriptional regulator, LysR family YP_003004992.1 PFAM: aldo/keto reductase; KEGG: ara:Arad_0567 oxidoreductase protein YP_003004993.1 TIGRFAM: phosphonate metabolism protein PhnP; PFAM: beta-lactamase domain protein; KEGG: spe:Spro_0512 carbon-phosphorus lyase complex accessory protein YP_003004994.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: yen:YE0470 ribose 1,5-bisphosphokinase YP_003004995.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: Amidohydrolase 3; amidohydrolase; KEGG: spe:Spro_0515 phosphonate metabolism protein PhnM YP_003004996.1 KEGG: ypg:YpAngola_A4026 phosphonate ABC transporter ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_003004997.1 KEGG: spe:Spro_0517 phosphonates transport ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_003004998.1 PFAM: phosphonate metabolism PhnJ; KEGG: yps:YPTB0513 protein in phn operon YP_003004999.1 PFAM: phosphonate metabolism; KEGG: spe:Spro_0519 phosphonate metabolism YP_003005000.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: cko:CKO_03770 carbon-phosphorus lyase complex subunit YP_003005001.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: spe:Spro_0521 phosphonate metabolism PhnG YP_003005002.1 may be involved in phosphonate uptake and biodegradation YP_003005003.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: plu:plu0404 hypothetical protein YP_003005004.1 KEGG: yps:YPTB1848 hypothetical protein YP_003005005.1 KEGG: esa:ESA_01406 hypothetical protein YP_003005006.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_003005007.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_003005008.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_003005009.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; KEGG: bha:BH2703 hypothetical protein YP_003005010.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA1520 glutamate/aspartate:proton symporter YP_003005011.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1519 transcriptional regulator CysB-like protein YP_003005012.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: pmr:PMI3583 hydrogenase formation protein YP_003005013.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yen:YE2798 hydrogenase-4 component A YP_003005014.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: yen:YE2799 hydrogenase 4 subunit B YP_003005015.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: yen:YE2800 hydrogenase-4 component C YP_003005016.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: yen:YE2801 hydrogenase 4 subunit D YP_003005017.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_003005018.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: yen:YE2803 hydrogenase 4 subunit F YP_003005019.1 PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: pmr:PMI2522 hydrogenase-4 component G YP_003005020.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_003005021.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: yen:YE2806 hydrogenase-4 component I YP_003005022.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: yen:YE2807 hydrogenase-4 component J YP_003005023.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_003005024.1 KEGG: mmw:Mmwyl1_0663 putative transcriptional regulator YP_003005025.1 KEGG: vco:VC0395_0747 hypothetical protein YP_003005026.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yen:YE2809 4Fe-4S ferrodoxin YP_003005027.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: yen:YE2810 formate dehydrogenase H YP_003005028.1 PFAM: AAA-4 family protein; KEGG: cja:CJA_1578 putative ATP-dependent DNA helicase YP_003005029.1 KEGG: aeh:Mlg_2299 cobyrinic acid a,c-diamide synthase YP_003005030.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; GAF domain protein; KEGG: yen:YE2811 putative hydrogenlyase transcriptional activator YP_003005031.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA1503 proton glutamate symport protein YP_003005032.1 PFAM: regulatory protein TetR; HMG-I and HMG-Y DNA-binding domain protein; KEGG: pzu:PHZ_c3419 transcriptional regulator, TetR family YP_003005033.1 KEGG: nmu:Nmul_A0946 putative glutathione S-transferase YP_003005034.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: eca:ECA1501 LysR family transcriptional regulator YP_003005035.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1500 aspartate racemase YP_003005036.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_003005037.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_003005038.1 KEGG: xfa:XF1742 hypothetical protein YP_003005039.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_1760 short-chain dehydrogenase/reductase SDR YP_003005040.1 KEGG: kpn:KPN_01707 hypothetical protein YP_003005041.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfo:Pfl01_2475 major facilitator transporter YP_003005042.1 PFAM: AraC-type transcriptional regulator domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: kpn:KPN_01705 putative AraC-type regulatory protein YP_003005043.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: msu:MS2162 MdaB protein YP_003005044.1 PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: abu:Abu_0783 zinc-containing NADP-dependent alcohol dehydrogenase YP_003005045.1 KEGG: eca:ECA2148 putative ABC transport ATP-binding subunit; TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter related; SMART: AAA ATPase YP_003005046.1 TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter related; KEGG: spe:Spro_1424 ABC transporter-related protein YP_003005047.1 TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; KEGG: eca:ECA2146 putative branched-chain amino acid transport system, permease component YP_003005048.1 TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; KEGG: eca:ECA2145 putative branched-chain amino acid transport system, permease component YP_003005049.1 TIGRFAM: urea ABC transporter, urea binding protein; PFAM: Extracellular ligand-binding receptor; KEGG: esa:ESA_01770 hypothetical protein YP_003005050.1 PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA2143 GntR family transcriptional regulator YP_003005051.1 KEGG: eca:ECA2142 UreA amidolyase; TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Allophanate hydrolase subunit 1; RimK domain protein ATP-grasp; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; SMART: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1 YP_003005052.1 catalyzes the hydrolysis of allophanate YP_003005054.1 KEGG: eca:ECA1472 hypothetical protein YP_003005055.1 PFAM: Protein of unknown function DUF1971; KEGG: eca:ECA1474 hypothetical protein YP_003005056.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: eca:ECA1475 hypothetical protein YP_003005057.1 KEGG: sew:SeSA_A4796 P-18 protein YP_003005058.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: yps:YPTB0599 AraC/XylS family transcription factor YP_003005059.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: kpe:KPK_2661 transcriptional regulator, MarR family YP_003005060.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bha:BH2078 oligopeptide ABC transporter ATP-binding protein YP_003005061.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bha:BH2077 oligopeptide ABC transporter ATP-binding protein YP_003005062.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pmr:PMI2945 ABC transporter, permease protein YP_003005063.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pmr:PMI2946 ABC-transporter, permease protein YP_003005064.1 TIGRFAM: nickel ABC transporter, periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5; KEGG: pmr:PMI2947 ABC transporter. substrate-binding protein YP_003005065.1 PFAM: Methyltransferase type 11; NodS family protein; methyltransferase small; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: msu:MS0467 SmtA protein YP_003005066.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: hch:HCH_03207 catalase/peroxidase HPI YP_003005067.1 PFAM: LrgA family protein; KEGG: ses:SARI_00720 hypothetical protein YP_003005068.1 PFAM: LrgB family protein; KEGG: esa:ESA_01093 hypothetical protein YP_003005069.1 PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bxe:Bxe_A1171 AraC family transcriptional regulator YP_003005070.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_003005071.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: eca:ECA1920 hypothetical protein YP_003005072.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: cko:CKO_04246 hypothetical protein YP_003005073.1 PFAM: protein of unknown function DUF162; KEGG: eca:ECA1918 hypothetical protein YP_003005074.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: esa:ESA_01129 hypothetical protein YP_003005075.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA3201 hypothetical protein YP_003005076.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: aav:Aave_2525 integral membrane sensor signal transduction histidine kinase YP_003005077.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcj:BCAM0111 two-component regulatory system, response regulator protein YP_003005078.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bmj:BMULJ_04150 RND family efflux transporter MFP subunit YP_003005079.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: rso:RSp0312 multidrug efflux system transmembrane protein YP_003005080.1 PFAM: N-acetyltransferase; KEGG: mxa:MXAN_1194 N-acetyltransferase family protein YP_003005082.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rec:RHECIAT_CH0003333 probable transcriptional regulator protein, LysR family YP_003005083.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; Osmosensory transporter coiled coil; major facilitator superfamily MFS_1; KEGG: eta:ETA_32990 proline/betaine transporter YP_003005084.1 PFAM: protein of unknown function DUF1272; KEGG: atc:AGR_C_4366 hypothetical protein YP_003005085.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: spe:Spro_2927 Dyp-type peroxidase family protein YP_003005086.1 KEGG: spe:Spro_2928 hypothetical protein YP_003005087.1 PFAM: iron permease FTR1; KEGG: spe:Spro_2929 iron permease FTR1 YP_003005088.1 KEGG: esa:ESA_01230 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003005089.1 PFAM: protein of unknown function DUF1611; KEGG: mes:Meso_0034 protein of unknown function DUF1611 YP_003005090.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA3116 putative mandelate racemase/muconate lactonizing enzyme YP_003005091.1 PFAM: aminotransferase class IV; KEGG: eca:ECA3117 D-alanine aminotransferase YP_003005092.1 PFAM: regulatory protein TetR; KEGG: eca:ECA0946 TetR family transcriptional regulator YP_003005093.1 KEGG: eca:ECA0947 hypothetical protein YP_003005095.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: eca:ECA3430 putative lipoprotein YP_003005096.1 PFAM: ImpA domain protein; KEGG: eca:ECA3431 hypothetical protein YP_003005097.1 TIGRFAM: type VI secretion protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: eca:ECA3432 putative virulence-associated protein YP_003005098.1 TIGRFAM: type VI secretion-associated protein, VC_A0119 family; PFAM: ImpA domain protein; KEGG: eca:ECA3433 hypothetical protein YP_003005099.1 TIGRFAM: type VI secretion-associated protein, VC_A0118 family; KEGG: eca:ECA3434 hypothetical protein YP_003005100.1 PFAM: sigma-54 factor interaction domain-containing protein; SMART: AAA ATPase; KEGG: eca:ECA3435 putative sigma-54 dependent transcriptional regulator YP_003005101.1 KEGG: eca:ECA3436 putative chaperone; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_003005102.1 TIGRFAM: type IV / VI secretion system protein, DotU family; KEGG: eca:ECA3437 hypothetical protein YP_003005103.1 TIGRFAM: type VI secretion protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: eca:ECA3438 hypothetical protein YP_003005104.1 TIGRFAM: type VI secretion lipoprotein, VC_A0113 family; KEGG: eca:ECA3439 putative lipoprotein YP_003005105.1 TIGRFAM: type VI secretion system FHA domain protein; PFAM: Forkhead-associated protein; KEGG: eca:ECA3440 hypothetical protein YP_003005106.1 TIGRFAM: type VI secretion protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: eca:ECA3441 hypothetical protein YP_003005107.1 TIGRFAM: type VI secretion protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: eca:ECA3442 hypothetical protein YP_003005108.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: eca:ECA3443 hypothetical protein YP_003005109.1 TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: eca:ECA3444 hypothetical protein YP_003005110.1 TIGRFAM: type VI secretion protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: eca:ECA3445 hypothetical protein YP_003005111.1 KEGG: kpe:KPK_2239 amidohydrolase family protein; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_003005112.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA3419 hypothetical protein YP_003005113.1 KEGG: bvi:Bcep1808_0453 hypothetical protein YP_003005115.1 TIGRFAM: YD repeat protein; KEGG: eca:ECA3421 rhs protein YP_003005116.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_0337 DNA-binding protein YP_003005117.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA3392 hypothetical protein YP_003005118.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA3419 hypothetical protein YP_003005119.1 KEGG: plu:plu3119 hypothetical protein YP_003005120.1 TIGRFAM: YD repeat protein; KEGG: eca:ECA3421 rhs protein YP_003005121.1 KEGG: eca:ECA3422 hypothetical protein YP_003005122.1 KEGG: eca:ECA3423 hypothetical protein YP_003005123.1 SMART: Ankyrin; KEGG: eca:ECA3424 putative lipoprotein YP_003005124.1 PFAM: Ankyrin; SMART: Ankyrin; KEGG: eca:ECA3424 putative lipoprotein YP_003005125.1 PFAM: Ankyrin; SMART: Ankyrin; KEGG: eca:ECA3425 putative lipoprotein YP_003005126.1 PFAM: PAAR repeat-containing protein; KEGG: eca:ECA3426 putative phospholipase YP_003005127.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA3427 hypothetical protein YP_003005128.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA2866 hypothetical protein YP_003005129.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_003005130.1 KEGG: eca:ECA3371 hypothetical protein YP_003005131.1 PFAM: Ferritin Dps family protein; KEGG: spe:Spro_2688 ferritin Dps family protein YP_003005132.1 KEGG: eca:ECA3507 hypothetical protein YP_003005133.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: kpe:KPK_1035 TonB-dependent receptor YP_003005134.1 with HmuTU is involved in the transport of hemin YP_003005135.1 PFAM: transport system permease protein; KEGG: sgl:SG1539 hemin ABC transporter permease component YP_003005136.1 PFAM: periplasmic binding protein; KEGG: yps:YPTB0338 ABC transporter, periplasmic hemin-binding protein HmuT YP_003005137.1 PFAM: Haemin-degrading family protein; KEGG: ecf:ECH74115_4856 hemin transport protein HmuS YP_003005139.1 PFAM: protein of unknown function DUF535; KEGG: eta:ETA_30810 putative virulence protein YP_003005140.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pag:PLES_39431 putative short-chain dehydrogenase YP_003005141.1 PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA1505 hypothetical protein YP_003005144.1 PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: eca:ECA1448 hypothetical protein YP_003005145.1 PFAM: protein of unknown function DUF1017; KEGG: eca:ECA1447 hypothetical protein YP_003005146.1 KEGG: eca:ECA1446 putative lipoprotein YP_003005148.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_003005149.1 PFAM: Nucleotidyl transferase; KEGG: eca:ECA1443 UTP--glucose-1-phosphate uridylyltransferase YP_003005150.1 KEGG: aha:AHA_2880 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase ; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_003005151.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: aha:AHA_2881 nucleotide sugar epimerase YP_003005152.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; KEGG: ecr:ECIAI1_2103 phosphomannomutase (PMM) YP_003005153.1 KEGG: spe:Spro_1599 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-6-phosphate isomerase type II YP_003005154.1 KEGG: kpn:KPN_02505 glycosyltransferase YP_003005155.1 PFAM: polysaccharide biosynthesis protein; KEGG: aci:ACIAD0075 putative polysaccharide transport protein YP_003005156.1 PFAM: glycosyl transferase family 2; KEGG: aci:ACIAD0074 glycosyl transferase family protein YP_003005157.1 KEGG: eca:ECA1440 dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; NAD-dependent epimerase/dehydratase YP_003005158.1 KEGG: eca:ECA1441 dTDP-6-deoxy-D-glucose-3,5 epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_003005159.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: eca:ECA1442 glucose-1-phosphate thymidylyltransferase YP_003005160.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: spe:Spro_0165 dTDP-glucose 4,6-dehydratase YP_003005161.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_003005162.1 PFAM: glycosyl transferase family 2; KEGG: ecx:EcHS_A2189 glycosyl transferase, group 2 family protein YP_003005163.1 PFAM: glycosyl transferase group 1; KEGG: aci:ACIAD0084 mannosyl transferase YP_003005164.1 PFAM: glycosyl transferase group 1; KEGG: kpe:KPK_1659 glycosyl transferase, group 1 family protein YP_003005165.1 PFAM: glycosyl transferase group 1; KEGG: kpe:KPK_1659 glycosyl transferase, group 1 family protein YP_003005166.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_003005167.1 PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: eca:ECA1418 protein-tyrosine-phosphatase YP_003005168.1 PFAM: polysaccharide export protein; KEGG: eca:ECA1417 putative polysaccharide export protein YP_003005169.1 PFAM: Integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: spe:Spro_1580 integral membrane protein TerC YP_003005170.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_003005171.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_003005172.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_003005173.1 KEGG: eca:ECA1410 putative ATPase YP_003005174.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_003005175.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003005176.1 PFAM: VirK family protein; KEGG: xac:XAC0435 VirK protein YP_003005177.1 KEGG: eca:ECA1405 hypothetical protein YP_003005178.1 KEGG: eca:ECA1404 hypothetical protein YP_003005179.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_003005180.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_003005181.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_003005182.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1394 molybdate ABC transporter permease protein YP_003005183.1 with ModCB is involved in the high-affinity transport of molybdate YP_003005184.1 KEGG: kpe:KPK_3803 hypothetical protein YP_003005185.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_003005186.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_003005187.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1389 UDP-galactose-4-epimerase YP_003005188.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_003005189.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: spe:Spro_1291 galactokinase YP_003005190.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_003005191.1 KEGG: eca:ECA1387 hypothetical protein YP_003005192.1 KEGG: eca:ECA1386 hypothetical protein YP_003005193.1 PFAM: outer membrane efflux protein; KEGG: eca:ECA1385 hypothetical protein YP_003005194.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: eca:ECA1384 putative copper efflux system protein YP_003005195.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1383 cation efflux system protein YP_003005196.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_003005197.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_003005198.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: spe:Spro_1283 nicotinamide mononucleotide transporter PnuC YP_003005199.1 TIGRFAM: quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A; KEGG: esa:ESA_02596 quinolinate synthetase YP_003005200.1 PFAM: protein of unknown function DUF554; KEGG: eca:ECA1376 hypothetical protein YP_003005201.1 TIGRFAM: tol-pal system protein YbgF; KEGG: eca:ECA1375 hypothetical protein YP_003005202.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: eca:ECA1374 peptidoglycan-associated outer membrane lipoprotein YP_003005203.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_003005204.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_003005205.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_003005206.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_003005207.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_003005208.1 TIGRFAM: cyd operon protein YbgE; KEGG: eca:ECA1368 hypothetical protein YP_003005209.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: eca:ECA1367 hypothetical protein YP_003005210.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: eca:ECA1366 cytochrome d ubiquinol oxidase subunit II YP_003005211.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: eca:ECA1365 cytochrome d ubiquinol oxidase subunit I YP_003005212.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_003005213.1 catalyzes the interconversion of succinyl-CoA and succinate YP_003005214.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: eca:ECA1362 dihydrolipoamide acetyltransferase YP_003005215.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_003005216.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: eca:ECA1360 succinate dehydrogenase iron-sulfur subunit YP_003005217.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_003005218.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: eca:ECA1358 succinate dehydrogenase cytochrome b556 small membrane subunit YP_003005219.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: see:SNSL254_A0791 succinate dehydrogenase, cytochrome b556 subunit YP_003005220.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_003005221.1 PFAM: LamB/YcsF family protein; KEGG: yen:YE2953 hypothetical protein YP_003005222.1 KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2 YP_003005223.1 PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1 YP_003005224.1 PFAM: protein of unknown function DUF34; KEGG: yen:YE2955 putative hydrolase-oxidase YP_003005225.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_003005226.1 PFAM: Protein of unknown function DUF1722; protein of unknown function DUF523; KEGG: eca:ECA1348 hypothetical protein YP_003005227.1 KEGG: eca:ECA1344 hypothetical protein YP_003005228.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_003005229.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_003005230.1 KEGG: eca:ECA1340 potassium-transporting ATPase C chain; TIGRFAM: potassium-transporting ATPase, C subunit; PFAM: K transporting ATPase KdpC subunit YP_003005231.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_003005232.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_003005233.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA1337 hypothetical protein YP_003005234.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_003005235.1 PFAM: SeqA family protein; KEGG: eca:ECA1335 replication initiation regulator SeqA YP_003005236.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: eca:ECA1334 hypothetical protein YP_003005237.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: eca:ECA1333 LexA regulated protein YP_003005238.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA1332 methyl-accepting chemotaxis protein YP_003005239.1 TIGRFAM: flavodoxin; PFAM: flavodoxin/nitric oxide synthase; KEGG: eca:ECA1330 flavodoxin FldA YP_003005240.1 PFAM: ferric-uptake regulator; KEGG: spe:Spro_1236 ferric uptake regulator YP_003005241.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003005242.1 TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: eca:ECA1327 PTS system, N-acetylglucosamine-specific IIABC component YP_003005243.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_003005244.1 KEGG: eca:ECA1325 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_003005245.1 PFAM: ROK family protein; KEGG: eca:ECA1324 N-acetylglucosamine repressor YP_003005246.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_003005247.1 PFAM: small multidrug resistance protein; KEGG: esa:ESA_01940 hypothetical protein YP_003005248.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_003005249.1 KEGG: eca:ECA1319 hypothetical protein; TIGRFAM: tRNA-i(6)A37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004 ; Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB YP_003005250.1 PFAM: PhoH family protein; KEGG: spe:Spro_1218 PhoH family protein YP_003005251.1 PFAM: protein of unknown function UPF0054; KEGG: eca:ECA1317 putative metalloprotease YP_003005252.1 PFAM: CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: eca:ECA1316 magnesium and cobalt efflux protein corc YP_003005253.1 Transfers the fatty acyl group on membrane lipoproteins YP_003005254.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA1314 glutamate and aspartate transporter subunit YP_003005255.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1313 glutamate/aspartate transport system permease protein YP_003005256.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1312 glutamate/aspartate transport system permease protein YP_003005257.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1311 glutamate/aspartate transport ATP-binding protein YP_003005258.1 PFAM: protein of unknown function DUF1451; KEGG: eca:ECA1310 hypothetical protein YP_003005259.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_003005260.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_003005261.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_003005262.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_003005263.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: esa:ESA_02690 hypothetical protein YP_003005264.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_003005265.1 KEGG: eca:ECA1303 penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_003005266.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: yen:YE3003 cell wall shape-determining protein YP_003005267.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: eca:ECA1301 rare lipoprotein A YP_003005268.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_003005269.1 PFAM: protein of unknown function DUF493; KEGG: spe:Spro_1197 hypothetical protein YP_003005270.1 KEGG: eca:ECA1298 lipoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase YP_003005271.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_003005272.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: eca:ECA1296 twin argininte translocase protein A YP_003005273.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eta:ETA_23610 putative hydrolase YP_003005274.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: eca:ECA1295 hypothetical protein YP_003005275.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_003005276.1 PFAM: arsenate reductase and related; KEGG: eca:ECA1292 hypothetical protein YP_003005277.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_003005278.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: eca:ECA1290 putative D-alanyl-D-alanine carboxypeptidase YP_003005279.1 KEGG: ypi:YpsIP31758_1253 hypothetical protein YP_003005280.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_003005281.1 PFAM: protein of unknown function DUF699 ATPase putative; GCN5-related N-acetyltransferase; KEGG: eca:ECA1266 putative acetyltransferase YP_003005282.1 PFAM: protein of unknown function DUF441; KEGG: eca:ECA1265 hypothetical protein YP_003005283.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_003005284.1 PFAM: NlpBDapX family lipoprotein; KEGG: eca:ECA1263 lipoprotein YP_003005285.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_003005286.1 PFAM: amino acid-binding ACT domain protein; KEGG: spe:Spro_3510 glycine cleavage system transcriptional repressor YP_003005287.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_003005288.1 PFAM: peptidase M48 Ste24p; KEGG: eca:ECA1259 hypothetical protein YP_003005289.1 KEGG: esa:ESA_00766 hypothetical protein; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_003005290.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_003005291.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: eca:ECA1256 uracil transporter YP_003005292.1 KEGG: eca:ECA1255 uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_003005293.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_003005294.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: yen:YE1125 phosphoribosylglycinamide formyltransferase YP_003005295.1 negative regulator of the mglBAC operon for galactose utilization YP_003005296.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: efe:EFER_2235 methyl-galactoside transporter subunit ; periplasmic-binding component of ABC superfamily YP_003005297.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_003005298.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_003005299.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: pfo:Pfl01_2802 extracellular solute-binding protein YP_003005300.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pfo:Pfl01_2801 amino acid ABC transporter permease YP_003005301.1 PFAM: periplasmic binding protein; KEGG: yen:YE3190 hypothetical protein YP_003005302.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: spe:Spro_1016 TonB-dependent siderophore receptor YP_003005303.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE1124 spermidine acetyltransferase YP_003005304.1 PFAM: protein of unknown function DUF214; KEGG: eca:ECA1224 hypothetical protein YP_003005305.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: spe:Spro_1158 putative ABC transporter ATP-binding protein YbbA YP_003005306.1 PFAM: lipolytic protein G-D-S-L family; KEGG: esa:ESA_02772 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 YP_003005307.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA1221 short chain dehydrogenase YP_003005308.1 PFAM: Thioredoxin domain; KEGG: eca:ECA1220 putative thioredoxin YP_003005309.1 TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: eca:ECA1219 competence damage-inducible protein A YP_003005310.1 PFAM: YfaZ family protein; KEGG: eca:ECA1217 hypothetical protein YP_003005311.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA1215 O-succinylbenzoic acid--CoA ligase YP_003005312.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_003005313.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_003005314.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_003005315.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_003005316.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: eca:ECA1210 menaquinone-specific isochorismate synthase YP_003005317.1 KEGG: eca:ECA1204 phosphotransfer intermediate protein in two-component regulatory system with RcsBC; PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein YP_003005318.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_003005319.1 PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: eca:ECA1202 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_003005320.1 negatively supercoils closed circular double-stranded DNA YP_003005321.1 KEGG: eca:ECA1200 3-demethylubiquinone-9 3-methyltransferase; TIGRFAM: ubiquinone biosynthesis O-methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_003005322.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003005323.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_003005324.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_003005325.1 PFAM: band 7 protein; SMART: band 7 protein; KEGG: eca:ECA1196 hypothetical protein YP_003005326.1 PFAM: protein of unknown function DUF107; KEGG: eca:ECA1195 hypothetical protein YP_003005327.1 KEGG: eca:ECA1194 copper efflux regulator; TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR YP_003005328.1 TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA1193 copper exporting ATPase YP_003005329.1 PFAM: GumN family protein; KEGG: eca:ECA1192 hypothetical protein YP_003005330.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: eca:ECA1191 hypothetical protein YP_003005331.1 PFAM: glycoside hydrolase family 28; KEGG: eca:ECA1190 putative polygalacturonase YP_003005332.1 PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; SMART: chemotaxis sensory transducer; KEGG: bac:BamMC406_6172 methyl-accepting chemotaxis sensory transducer YP_003005333.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_003005334.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_003005335.1 KEGG: eca:ECA1181 ferrochelatase; TIGRFAM: ferrochelatase; PFAM: ferrochelatase YP_003005336.1 TIGRFAM: adenylate kinase; PFAM: adenylate kinase; adenylate kinase lid domain protein; KEGG: spe:Spro_1139 nucleoside-triphosphate--adenylate kinase YP_003005337.1 molecular chaperone YP_003005338.1 KEGG: spe:Spro_1137 recombination protein RecR; TIGRFAM: recombination protein RecR; PFAM: Zinc finger C4-type, RecR; TOPRIM domain protein; SMART: Toprim sub domain protein YP_003005339.1 PFAM: conserved hypothetical protein; KEGG: see:SNSL254_A0536 hypothetical protein YP_003005340.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_003005341.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_003005342.1 PFAM: protein of unknown function DUF454; KEGG: esa:ESA_02802 hypothetical protein YP_003005343.1 PFAM: tRNA-hydroxylase; KEGG: vsp:VS_2052 tRNA-hydroxylase YP_003005344.1 PFAM: Primosomal replication priB and priC; KEGG: eca:ECA1173 primosomal replication protein N'' YP_003005345.1 KEGG: eta:ETA_24780 hypothetical protein YP_003005346.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_003005347.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_003005348.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA1170 acriflavine resistance protein A YP_003005349.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B YP_003005350.1 TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: spe:Spro_1125 50S ribosomal protein L31 type B YP_003005351.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_003005352.1 KEGG: eca:ECA1166 hypothetical protein YP_003005353.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_003005354.1 TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: eca:ECA1164 putative 6-O-methylguanine DNA methyltransferase YP_003005355.1 KEGG: eca:ECA1163 lipoprotein YP_003005356.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; KEGG: eca:ECA1162 acyl-CoA thioesterase II YP_003005357.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: eca:ECA1161 ammonium transporter YP_003005358.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_003005359.1 PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: eca:ECA1159 putative multidrug transporter membrane\ATP-binding components YP_003005360.1 PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: eca:ECA1158 putative multidrug transporter membrane\ATP-binding components YP_003005361.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: eca:ECA1157 transcription regulator AsnC YP_003005362.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eca:ECA1156 putative pyridoxal-phosphate dependent protein YP_003005363.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: eca:ECA1155 queuosine biosynthesis protein QueC YP_003005364.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: eca:ECA1153 hypothetical protein YP_003005365.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: eca:ECA1152 peptidyl-prolyl cis-trans isomerase (rotamase D) YP_003005366.1 histone-like DNA-binding protein YP_003005367.1 KEGG: eca:ECA1150 DNA-binding ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16 lon domain protein; AAA ATPase YP_003005368.1 binds and unfolds substrates as part of the ClpXP protease YP_003005369.1 KEGG: sgl:SG0671 ATP-dependent Clp protease proteolytic subunit; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: peptidase S14 ClpP YP_003005370.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_003005371.1 PFAM: BolA family protein; KEGG: eca:ECA1146 transcriptional regulator BolA YP_003005372.1 PFAM: Uncharacterized lipoprotein; KEGG: eca:ECA1145 hypothetical protein YP_003005373.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_003005374.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: COX aromatic rich domain protein; cytochrome c oxidase subunit II; KEGG: eca:ECA1143 cytochrome o ubiquinol oxidase subunit II YP_003005375.1 KEGG: eca:ECA1142 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase, subunit I; PFAM: cytochrome c oxidase subunit I YP_003005376.1 TIGRFAM: cytochrome o ubiquinol oxidase, subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: eca:ECA1141 cytochrome o ubiquinol oxidase subunit III YP_003005377.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: eca:ECA1140 cytochrome o ubiquinol oxidase subunit IV YP_003005378.1 converts protoheme IX and farnesyl diphosphate to heme O YP_003005379.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1138 transporter YP_003005380.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_003005381.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_003005382.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA1135 hypothetical protein YP_003005383.1 Required for the synthesis of the thiazole moiety YP_003005384.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; KEGG: eca:ECA1133 exodeoxyribonuclease VII small subunit YP_003005385.1 PFAM: Polyprenyl synthetase; KEGG: eca:ECA1132 geranyltranstransferase YP_003005386.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_003005387.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_003005388.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_003005389.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_003005390.1 KEGG: pmr:PMI0082 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase YP_003005391.1 KEGG: eca:ECA1126 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding YP_003005392.1 PFAM: ATP-cone domain protein; KEGG: eca:ECA1125 transcriptional regulator NrdR YP_003005393.1 P-type ATPase involved in magnesium influx YP_003005394.1 KEGG: eca:ECA1124 hypothetical protein YP_003005395.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_003005396.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_003005397.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: efe:EFER_2618 SecYEG protein translocase auxillary subunit YP_003005398.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_003005399.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_003005400.1 PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein YP_003005401.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: yen:YE3174 putative alkyl hydroperoxide reductase subunit C YP_003005402.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_003005403.1 TIGRFAM: branched-chain amino acid transport system II carrier protein; PFAM: branched-chain amino acid transport system II carrier protein; KEGG: eca:ECA1114 branched-chain amino acid transport system II carrier protein YP_003005404.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_003005405.1 TIGRFAM: phosphate binding protein; KEGG: eca:ECA1112 putative phosphate binding protein YP_003005406.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_003005407.1 KEGG: eca:ECA1110 phosphate regulon response regulator; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver YP_003005408.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: spe:Spro_1040 exonuclease subunit SbcD YP_003005409.1 PFAM: SMC domain protein; KEGG: eca:ECA1108 exonuclease YP_003005410.1 PFAM: ROK family protein; KEGG: eca:ECA1107 fructokinase YP_003005411.1 PFAM: putative exonuclease RdgC; KEGG: spe:Spro_1027 recombination associated protein YP_003005412.1 PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1105 putative methyl-accepting chemotaxis protein YP_003005413.1 PFAM: protein of unknown function DUF1255; KEGG: eca:ECA1104 hypothetical protein YP_003005414.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_003005415.1 KEGG: eca:ECA1102 L-asparaginase precursor; TIGRFAM: L-asparaginase, type II; PFAM: Asparaginase/glutaminase YP_003005416.1 PFAM: Methionine synthase vitamin-B12 independent; KEGG: bbt:BBta_5702 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YP_003005417.1 KEGG: eca:ECA1090 putative lipoprotein YP_003005418.1 TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: spe:Spro_1624 HAD family hydrolase YP_003005419.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2075 LysR family transcriptional regulator YP_003005420.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: eca:ECA2074 hypothetical protein YP_003005421.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: bur:Bcep18194_A4727 major facilitator transporter YP_003005422.1 PFAM: major facilitator superfamily MFS_1; KEGG: spq:SPAB_05417 hypothetical protein YP_003005423.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0956 putative acetyltransferase YP_003005424.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pol:Bpro_3436 transcriptional regulator, LysR family YP_003005425.1 KEGG: eca:ECA3090 hypothetical protein YP_003005426.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: eca:ECA1089 hypothetical protein YP_003005427.1 KEGG: eca:ECA1088 hypothetical protein YP_003005428.1 KEGG: eca:ECA1087 putative lipoprotein YP_003005429.1 KEGG: eca:ECA1086 putative signaling protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003005430.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: eca:ECA1082 phosphonoacetate hydrolase YP_003005431.1 PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: mmw:Mmwyl1_3284 major facilitator transporter YP_003005432.1 PFAM: Pyoverdine biosynthesis protein; Taurine catabolism dioxygenase TauD/TfdA; KEGG: pen:PSEEN0964 clavaminate synthase-like; PvcA-like domain YP_003005433.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pen:PSEEN0963 hydrolase; predicted phosphatase YP_003005434.1 PFAM: Pyoverdine biosynthesis protein; KEGG: pen:PSEEN0962 siderophore biosynthesis protein PvcA-like YP_003005435.1 PFAM: PEBP family protein; KEGG: rfr:Rfer_3962 YbcL YP_003005436.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: spe:Spro_2944 AraC family transcriptional regulator YP_003005437.1 PFAM: Ketopantoate reductase ApbA/PanE domain protein; KEGG: eca:ECA1579 2-dehydropantoate 2-reductase YP_003005438.1 PFAM: regulatory protein TetR; KEGG: mno:Mnod_7468 transcriptional regulator, TetR family YP_003005439.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mno:Mnod_7469 short-chain dehydrogenase/reductase SDR YP_003005440.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: pst:PSPTO_0818 MarR family transcriptional regulator YP_003005441.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: smd:Smed_5816 NADP oxidoreductase coenzyme F420-dependent YP_003005442.1 PFAM: nitroreductase; KEGG: pla:Plav_2473 nitroreductase YP_003005443.1 This protein performs the mismatch recognition step during the DNA repair process YP_003005444.1 KEGG: eca:ECA1052 lipoprotein involved with copper homeostasis and adhesion YP_003005445.1 PFAM: YaeQ family protein; KEGG: yen:YE3261 hypothetical protein YP_003005446.1 PFAM: protein of unknown function UPF0253; KEGG: spe:Spro_3762 hypothetical protein YP_003005447.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_003005448.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_003005449.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA1048 hypothetical protein YP_003005450.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_003005451.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_003005452.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_003005453.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_003005454.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_003005455.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_003005456.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_003005457.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: eca:ECA1040 periplasmic chaperone YP_003005458.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_003005459.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_003005460.1 PFAM: phosphatidate cytidylyltransferase; KEGG: eca:ECA1037 CDP-diglyceride synthase YP_003005461.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: eca:ECA1036 undecaprenyl pyrophosphate synthetase YP_003005462.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_003005463.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_003005464.1 Catalyzes the phosphorylation of UMP to UDP YP_003005465.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_003005466.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_003005467.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: eta:ETA_08880 methionine aminopeptidase YP_003005468.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_003005469.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_003005470.1 KEGG: yen:YE3288 hypothetical protein YP_003005471.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003005472.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_003005473.1 PFAM: protein of unknown function DUF446; KEGG: eca:ECA1024 hypothetical protein YP_003005474.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_003005475.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1019 lysine decarboxylase family protein YP_003005476.1 PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: eca:ECA1018 exonuclease IX YP_003005477.1 KEGG: eca:ECA1017 putative RNA 2'-O-ribose methyltransferase YP_003005478.1 PFAM: protein of unknown function DUF423; KEGG: eca:ECA1016 hypothetical protein YP_003005479.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_003005480.1 PFAM: protein of unknown function DUF903; KEGG: eca:ECA1013 putative lipoprotein YP_003005481.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: eca:ECA1012 cysteine sulfinate desulfinase YP_003005482.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: eca:ECA1011 putative Fe-S metabolism associated protein YP_003005483.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: eca:ECA1010 hypothetical protein YP_003005484.1 PFAM: GCN5-related N-acetyltransferase; KEGG: swd:Swoo_4463 GCN5-related N-acetyltransferase YP_003005485.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: asa:ASA_0954 D-3-phosphoglycerate dehydrogenase YP_003005486.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sse:Ssed_0582 GCN5-related N-acetyltransferase YP_003005487.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbp:Sbal223_1772 GCN5-related N-acetyltransferase YP_003005488.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_003005489.1 KEGG: eca:ECA1000 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin YP_003005490.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_003005491.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA0994 protease III precursor YP_003005492.1 KEGG: eca:ECA0992 putative prepilin peptidase dependent protein c precursor YP_003005493.1 KEGG: eca:ECA0991 hypothetical protein YP_003005494.1 KEGG: eca:ECA0990 hypothetical protein YP_003005495.1 KEGG: eca:ECA0989 hypothetical protein YP_003005496.1 KEGG: eca:ECA0988 thymidylate synthase; TIGRFAM: thymidylate synthase; PFAM: thymidylate synthase YP_003005497.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_003005498.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_003005499.1 hydrolyzes diadenosine polyphosphate YP_003005500.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_003005501.1 PFAM: Integral membrane protein TerC; KEGG: eca:ECA0983 hypothetical protein YP_003005502.1 PFAM: protein of unknown function DUF903; KEGG: eca:ECA0982 putative lipoprotein YP_003005503.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_003005504.1 KEGG: eca:ECA0979 hypothetical protein YP_003005505.1 PFAM: protein of unknown function DUF469; KEGG: spe:Spro_4041 hypothetical protein YP_003005506.1 KEGG: eca:ECA0977 tRNA (guanine-N(7))-methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: putative methyltransferase YP_003005507.1 KEGG: eca:ECA0976 adenine DNA glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop YP_003005508.1 PFAM: Fe(II) trafficking protein YggX; KEGG: esa:ESA_00329 hypothetical protein YP_003005509.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_003005510.1 PFAM: amino acid permease-associated region; KEGG: yps:YPTB1935 APC family L-asparagine permease YP_003005511.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: eca:ECA0967 ornithine decarboxylase YP_003005513.1 PFAM: protein of unknown function DUF1440; KEGG: eum:ECUMN_0321 conserved hypothetical protein; putative inner membrane protein YP_003005514.1 KEGG: ssn:SSON_P063 ISSfl1 ORF1 YP_003005516.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: rle:RL2360 hypothetical protein YP_003005517.1 KEGG: afw:Anae109_4407 hypothetical protein YP_003005518.1 KEGG: mlo:mlr5488 hypothetical protein YP_003005519.1 PFAM: helix-turn-helix HxlR type; KEGG: ccs:CCNA_03479 transcriptional regulator, MarR family YP_003005520.1 KEGG: eca:ECA0549 putative plasmid transfer protein YP_003005521.1 PFAM: acriflavin resistance protein; KEGG: esa:ESA_pESA3p05444 hypothetical protein YP_003005522.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bbt:BBta_0809 hypothetical protein YP_003005523.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: esa:ESA_pESA3p05442 hypothetical protein YP_003005524.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: kpe:KPK_2665 DNA-binding response regulator YP_003005525.1 PFAM: MltA-interacting MipA family protein; KEGG: esa:ESA_pESA3p05440 hypothetical protein YP_003005526.1 PFAM: Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: spe:Spro_3212 hypothetical protein YP_003005527.1 KEGG: aha:AHA_3054 hypothetical protein YP_003005528.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA1009 biotin sulfoxide reductase YP_003005529.1 PFAM: conserved hypothetical protein; KEGG: ecc:c3738 hypothetical protein YP_003005530.1 PFAM: Rhamnogalacturonate lyase; KEGG: eca:ECA0804 rhamnogalacturonate lyase YP_003005531.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: plu:plu0977 hypothetical protein YP_003005532.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu1490 hypothetical protein YP_003005533.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: spe:Spro_4196 hypothetical protein YP_003005534.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_003005535.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: azo:azo1247 LysR family transcriptional regulator YP_003005536.1 KEGG: reh:H16_A0477 3-isopropylmalate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_003005537.1 KEGG: eca:ECA3786 hypothetical protein YP_003005538.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: eca:ECA0930 permease YP_003005539.1 PFAM: extracellular solute-binding protein family 1; KEGG: hch:HCH_03296 ABC-type sugar transport system, periplasmic component YP_003005540.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hch:HCH_03297 ABC-type sugar transport system, permease components YP_003005541.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hch:HCH_03298 ABC-type sugar transport system, permease component YP_003005542.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rle:RL0095 putative ATP-binding component of ABC transporter protein YP_003005543.1 KEGG: hch:HCH_04196 beta-lactamase superfamily hydrolase YP_003005544.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: hch:HCH_03302 transcriptional regulator YP_003005545.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0916 LysR family transcriptional regulator YP_003005546.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; peptidase S15; KEGG: eca:ECA0915 hypothetical protein YP_003005547.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA0914 putative component of polysulfide reductase YP_003005548.1 TIGRFAM: cytochrome c nitrite reductase, NrfD subunit; PFAM: Polysulphide reductase NrfD; KEGG: eca:ECA0913 putative component of polysulfide reductase YP_003005549.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0912 hypothetical protein YP_003005550.1 PFAM: FMN-binding domain protein; KEGG: eca:ECA0911 hypothetical protein YP_003005551.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: eca:ECA0910 putative flavoprotein subunit of a reductase YP_003005552.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: eca:ECA0909 alkylated DNA repair protein YP_003005553.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003005554.1 KEGG: eca:ECA0907 putative DNA-3-methyladenine glycosylase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein YP_003005555.1 PFAM: transmembrane pair domain protein; KEGG: eca:ECA0906 hypothetical protein YP_003005556.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0905 LysR family transcriptional regulator YP_003005557.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: eca:ECA0904 fumarate hydratase class I, aerobic YP_003005558.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_003005559.1 detoxifies nitric oxide using NADH YP_003005560.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_003005561.1 with TehA confers resistance to tellurite YP_003005562.1 DHBP synthase; functions during riboflavin biosynthesis YP_003005563.1 PFAM: protein of unknown function DUF526; KEGG: spe:Spro_4287 hypothetical protein YP_003005564.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_003005565.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_003005566.1 PFAM: protein of unknown function DUF540; KEGG: eca:ECA0895 putative sulfate transport protein CysZ YP_003005567.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_003005568.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: eum:ECUMN_2737 phosphohistidinoprotein-hexose phosphotransferase component of PTS system (HPr) YP_003005569.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_003005570.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_003005571.1 PFAM: helix-turn-helix HxlR type; KEGG: gbe:GbCGDNIH1_1161 transcriptional regulator, MarR family YP_003005572.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pae:PA2841 enoyl-CoA hydratase YP_003005573.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: spe:Spro_3451 integral membrane sensor signal transduction histidine kinase YP_003005574.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: eca:ECA0889 two-component system response regulator YP_003005575.1 TIGRFAM: cysteine synthase B; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eca:ECA0886 cysteine synthase B YP_003005576.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: eca:ECA0882 hypothetical protein YP_003005577.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: eca:ECA0932 permease YP_003005578.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: eca:ECA0933 LuxR family transcriptional regulator YP_003005579.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0934 putative acetyltransferase YP_003005580.1 KEGG: eca:ECA0686 sugar fermentation stimulation protein YP_003005581.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; KEGG: eca:ECA3379 putative glycosyltransferase YP_003005582.1 PFAM: protein of unknown function DUF1131; KEGG: eca:ECA0881 hypothetical protein YP_003005583.1 PFAM: ABC transporter domain protein; ABC transporter related; SbmABacA family protein; SMART: AAA ATPase; KEGG: eca:ECA0880 putative ABC transporter ATP-binding protein YP_003005584.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA0879 putative zinc protease YP_003005585.1 PFAM: TonB-dependent receptor plug; KEGG: eca:ECA0878 hypothetical protein YP_003005586.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: eca:ECA0877 TonB-like protein YP_003005587.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0875 putative acetyltransferase YP_003005588.1 PFAM: coproporphyrinogen III oxidase; KEGG: eca:ECA0874 coproporphyrinogen III oxidase YP_003005589.1 PFAM: protein of unknown function DUF188; KEGG: spe:Spro_3465 hypothetical protein YP_003005590.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_003005591.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA0847 putative MutT/NUDIX family protein YP_003005592.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: eca:ECA0843 manganese transport protein MntH YP_003005593.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_003005594.1 PFAM: ATP-NAD/AcoX kinase; KEGG: eca:ECA0841 inorganic polyphosphate/ATP-NAD kinase YP_003005595.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: eca:ECA0840 recombination and repair protein YP_003005596.1 PFAM: SmpA/OmlA domain protein; KEGG: eca:ECA0839 hypothetical protein YP_003005597.1 PFAM: protein of unknown function UPF0125; KEGG: sgl:SG1802 hypothetical protein YP_003005598.1 PFAM: cyclase/dehydrase; KEGG: eca:ECA0837 hypothetical protein YP_003005599.1 TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; KEGG: cko:CKO_03942 hypothetical protein YP_003005600.1 PFAM: transposase IS4 family protein; KEGG: sfx:S4808 hypothetical protein YP_003005602.1 KEGG: smd:Smed_1902 hypothetical protein YP_003005603.1 PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: eca:ECA1499 pectin lyase YP_003005604.1 KEGG: ilo:IL2017 type II secretory pathway, component PulM YP_003005605.1 KEGG: vvy:VV0222 type II secretory pathway, component EpsL YP_003005606.1 KEGG: spe:Spro_4244 general secretion pathway protein K YP_003005607.1 KEGG: ecf:ECH74115_B0009 general secretion pathway protein J YP_003005608.1 PFAM: type II secretion system protein I/J; KEGG: hha:Hhal_2374 general secretion pathway protein I YP_003005609.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: ilo:IL2023 type II secretory pathway, pseudopilin PulG YP_003005610.1 PFAM: type II secretion system protein; KEGG: eca:ECA3107 general secretion pathway protein F YP_003005611.1 PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: aha:AHA_0570 general secretory pathway protein E YP_003005612.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: kpe:KPK_4576 pullulanase secretion envelope protein PulD YP_003005613.1 KEGG: spe:Spro_4252 hypothetical protein YP_003005614.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: mxa:MXAN_6804 MATE efflux family protein YP_003005615.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pol:Bpro_3443 RND efflux system, outer membrane lipoprotein, NodT YP_003005616.1 PFAM: regulatory protein TetR; KEGG: pol:Bpro_3444 transcriptional regulator, TetR family YP_003005617.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: pol:Bpro_3445 secretion protein HlyD YP_003005618.1 PFAM: acriflavin resistance protein; KEGG: xfa:XF2083 cation efflux system protein YP_003005619.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: bch:Bcen2424_6530 short chain dehydrogenase YP_003005620.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_003005621.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mlo:mlr1595 short chain dehydrogenase YP_003005622.1 PFAM: helix-turn-helix HxlR type; KEGG: rso:RSc0210 hypothetical protein YP_003005623.1 KEGG: rso:RSc0209 hypothetical protein YP_003005624.1 KEGG: ret:RHE_PC00048 hypothetical protein YP_003005625.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA0828 putative amino acid-binding periplasmic protein YP_003005626.1 KEGG: dar:Daro_3104 hypothetical protein YP_003005627.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_003005628.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sea:SeAg_B4544 invertase YP_003005629.1 PFAM: Myo-inositol catabolism IolB domain protein; KEGG: eca:ECA1465 hypothetical protein YP_003005630.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: eca:ECA1464 putative myo-inositol catabolism protein YP_003005631.1 PFAM: PfkB domain protein; KEGG: eca:ECA1463 putative carbohydrate kinase YP_003005632.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: eca:ECA1462 oxidoreductase YP_003005633.1 PFAM: inner-membrane translocator; KEGG: eca:ECA1461 putative sugar ABC transporter, permease protein YP_003005634.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cko:CKO_03989 hypothetical protein YP_003005635.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA1459 putative sugar ABC transporter, periplasmic protein YP_003005636.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: eca:ECA1458 putative myo-inositol 2-dehydrogenase YP_003005637.1 SMART: AAA ATPase; KEGG: rme:Rmet_4896 SMC protein-like protein YP_003005639.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: cko:CKO_03993 hypothetical protein YP_003005640.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: eca:ECA1456 putative aldehyde dehydrogenase YP_003005641.1 PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: eca:ECA1455 putative transcriptional regulator YP_003005642.1 KEGG: yen:YE3211 D-alanine--D-alanine ligase A; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp YP_003005643.1 PFAM: YCII-related; KEGG: yen:YE1740 hypothetical protein YP_003005644.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bch:Bcen2424_4729 glyoxalase/bleomycin resistance protein/dioxygenase YP_003005645.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_2951 acetyltransferase YP_003005646.1 PFAM: DinI family protein; KEGG: yen:YE1408 putative stress response protein YP_003005647.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_03424 putative permease YP_003005648.1 PFAM: glycoside hydrolase family 43; KEGG: kpn:KPN_03423 putative glycoside hydrolase YP_003005649.1 KEGG: esa:ESA_01748 hypothetical protein YP_003005650.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pmy:Pmen_1643 GCN5-related N-acetyltransferase YP_003005651.1 KEGG: eca:ECA0825 hypothetical protein YP_003005652.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA0824 pyruvate-flavodoxin oxidoreductase YP_003005653.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA0821 hypothetical protein YP_003005654.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bpy:Bphyt_7127 GCN5-related N-acetyltransferase YP_003005655.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bpt:Bpet2973 MarR family transcriptional regulator YP_003005656.1 PFAM: secretion protein HlyD family protein; KEGG: maq:Maqu_0618 secretion protein HlyD family protein YP_003005657.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: maq:Maqu_0617 EmrB/QacA family drug resistance transporter YP_003005658.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0819 putative D-mannonate oxidoreductase YP_003005659.1 SMART: helix-turn-helix domain protein; KEGG: xau:Xaut_0314 XRE family transcriptional regulator YP_003005660.1 KEGG: eca:ECA0817 oligogalacturonide transporter YP_003005661.1 KEGG: eca:ECA0815 hypothetical protein YP_003005662.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA4072 ABC transporter ATP-binding protein YP_003005663.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA4073 ABC transporter ATP binding protein YP_003005664.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4074 ABC transporter permease protein YP_003005665.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4075 ABC transporter permease protein YP_003005666.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4076 ABC transporter, substrate binding protein YP_003005667.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA4077 putative mandelate racemase / muconate lactonizing enzyme YP_003005668.1 KEGG: ypy:YPK_0408 hypothetical protein YP_003005669.1 KEGG: eca:ECA0809 global regulatory protein YP_003005670.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_003005671.1 PFAM: protein of unknown function DUF485; KEGG: eca:ECA0807 hypothetical protein YP_003005672.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_003005673.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: eca:ECA0784 putative sodium/hydrogen antiporter YP_003005674.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: eca:ECA0783 putative permease YP_003005675.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_003005676.1 PFAM: TOBE domain protein; KEGG: cko:CKO_04088 hypothetical protein YP_003005677.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_04682 putative sn-glycerol-3-phosphate transport system permease YP_003005678.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_04681 putative sn-glycerol-3-phosphate transport system permease YP_003005679.1 PFAM: metallophosphoesterase; KEGG: kpn:KPN_04680 putative phosphohydrolase YP_003005680.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: kpe:KPK_4986 sugar ABC transporter, ATP-binding protein YP_003005681.1 PFAM: extracellular solute-binding protein family 1; KEGG: kpe:KPK_4987 ABC transporter, periplasmic substrate-binding protein YP_003005682.1 PFAM: sugar transferase; KEGG: vco:VC0395_A2640 putative capsule biosynthesis protein YP_003005683.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: pol:Bpro_3986 NAD-dependent epimerase/dehydratase YP_003005684.1 PFAM: polysaccharide biosynthesis protein CapD; Male sterility domain; dTDP-4-dehydrorhamnose reductase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: vch:VC0260 mannosyl-transferase YP_003005685.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_003005686.1 PFAM: helix-turn-helix HxlR type; KEGG: atc:AGR_C_1731 hypothetical protein YP_003005687.1 PFAM: Integrase catalytic region; KEGG: ypg:YpAngola_A2063 transposase YP_003005688.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypg:YpAngola_A2064 hypothetical protein YP_003005689.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; KEGG: spe:Spro_1601 UDP-glucose 4-epimerase YP_003005690.1 PFAM: transposase IS4 family protein; KEGG: ecr:ECIAI1_0543 putative transposase YP_003005691.1 PFAM: glycosyl transferase group 1; KEGG: spe:Spro_1603 glycosyl transferase group 1 YP_003005692.1 KEGG: ecl:EcolC_3406 integrase catalytic region YP_003005693.1 PFAM: transposase IS4 family protein; KEGG: ecr:ECIAI1_0543 putative transposase YP_003005695.1 PFAM: polysaccharide biosynthesis protein; KEGG: plu:plu4800 WzxA protein YP_003005696.1 KEGG: aav:Aave_1206 hypothetical protein YP_003005697.1 PFAM: FAD dependent oxidoreductase; KEGG: pin:Ping_0450 FAD dependent oxidoreductase YP_003005698.1 PFAM: glycosyl transferase family 2; KEGG: pin:Ping_0449 glycosyl transferase family protein YP_003005699.1 KEGG: pin:Ping_0447 dolichyl-phosphate beta-D-mannosyltransferase YP_003005700.1 KEGG: pin:Ping_0453 hypothetical protein YP_003005701.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: pin:Ping_0452 xylose isomerase domain-containing protein YP_003005702.1 KEGG: oan:Oant_2966 hypothetical protein YP_003005703.1 KEGG: pin:Ping_0448 hypothetical protein YP_003005705.1 KEGG: rsq:Rsph17025_4041 hypothetical protein YP_003005706.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypg:YpAngola_A2064 hypothetical protein YP_003005707.1 KEGG: yps:YPTB1892 putative transposase YP_003005708.1 PFAM: Integrase catalytic region; KEGG: ypg:YpAngola_A2063 transposase YP_003005709.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypg:YpAngola_A2064 hypothetical protein YP_003005710.1 KEGG: lhk:LHK_01280 transposase YP_003005711.1 PFAM: transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533; KEGG: sgl:SG1481 transposase YP_003005712.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA0776 hypothetical protein YP_003005713.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_003005714.1 KEGG: ypi:YpsIP31758_0882 peptide chain release factor 2 YP_003005715.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: spe:Spro_3890 ssDNA exonuclease RecJ YP_003005716.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_003005717.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: eca:ECA0770 site-specific tyrosine recombinase XerD YP_003005718.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA0769 transporter YP_003005719.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_003005720.1 PFAM: protein of unknown function DUF1434; KEGG: eca:ECA0760 hypothetical protein YP_003005721.1 PFAM: protein of unknown function DUF339; KEGG: eca:ECA0759 hypothetical protein YP_003005722.1 TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: eca:ECA0758 putative global regulator YP_003005723.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: kpe:KPK_0771 channel protein, hemolysin III family YP_003005724.1 KEGG: spe:Spro_3901 metal dependent phosphohydrolase YP_003005725.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: aha:AHA_3512 amino acid transporter LysE YP_003005726.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_003005727.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_003005728.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_003005729.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA0742 L-1,2-propanediol oxidoreductase YP_003005730.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_003005731.1 KEGG: yen:YE4016 alpha-acetolactate decarboxylase; TIGRFAM: alpha-acetolactate decarboxylase; PFAM: alpha-acetolactate decarboxylase YP_003005732.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0739 LysR family transcriptional regulator YP_003005733.1 KEGG: spe:Spro_0646 hypothetical protein YP_003005734.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0737 LysR family transcriptional regulator YP_003005735.1 PFAM: aldo/keto reductase; KEGG: eca:ECA0736 putative aldo/keto reductase YP_003005736.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_003005737.1 PFAM: DNA polymerase III psi subunit; KEGG: spe:Spro_0650 DNA polymerase III subunit psi YP_003005738.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_003005740.1 TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: eta:ETA_06690 purine nucleoside phosphorylase DeoD-type YP_003005741.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_003005742.1 KEGG: eca:ECA0728 thymidine phosphorylase; TIGRFAM: thymidine phosphorylase; pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like YP_003005743.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_003005744.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: yen:YE0453 GIY-YIG nuclease superfamily protein YP_003005745.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0724 putative acetyltransferase YP_003005746.1 PFAM: Sterol-binding domain protein; KEGG: eca:ECA0723 putative sterol transferase YP_003005747.1 PFAM: peptidase U32; KEGG: eca:ECA0722 putative protease YP_003005748.1 PFAM: peptidase U32; KEGG: yen:YE0449 hypothetical protein YP_003005749.1 PFAM: Luciferase-like monooxygenase; KEGG: yen:YE0442 hypothetical protein YP_003005750.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_003005751.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_003005752.1 KEGG: eca:ECA0716 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; RNA binding S1 domain protein; Exoribonuclease, phosphorolytic domain 2; KH type 1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein YP_003005753.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_003005754.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; tRNA pseudouridine synthase B; KEGG: eca:ECA0714 tRNA pseudouridine synthase B YP_003005755.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_003005756.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_003005757.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_003005758.1 PFAM: protein of unknown function DUF150; KEGG: ecm:EcSMS35_3466 hypothetical protein YP_003005759.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: spe:Spro_0486 preprotein translocase subunit SecG YP_003005760.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_003005761.1 KEGG: eca:ECA0699 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS YP_003005762.1 KEGG: kpe:KPK_0533 ATP-dependent metallopeptidase HflB; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; peptidase M41 FtsH extracellular; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_003005763.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_003005764.1 PFAM: protein of unknown function UPF0044; KEGG: eca:ECA0696 hypothetical protein YP_003005765.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: ses:SARI_04326 transcription elongation factor GreA YP_003005766.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_003005767.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_003005768.1 PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: eca:ECA0692 hypothetical protein YP_003005769.1 TIGRFAM: ribosomal protein L27; PFAM: ribosomal protein L27; KEGG: esa:ESA_03578 50S ribosomal protein L27 YP_003005770.1 TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: eca:ECA0690 50S ribosomal protein L21 YP_003005771.1 PFAM: Polyprenyl synthetase; KEGG: eca:ECA0689 octaprenyl diphosphate synthase YP_003005772.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: eca:ECA0688 hypothetical protein YP_003005773.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: eca:ECA0687 putative DNA-binding protein YP_003005774.1 oxidizes malate to oxaloacetate YP_003005775.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_003005776.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_003005777.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_003005778.1 synthesizes RNA primers at the replication forks YP_003005779.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_003005780.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pfl:PFL_2803 oxidoreductase, zinc-binding YP_003005781.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pfl:PFL_2805 short chain dehydrogenase/reductase family oxidoreductase YP_003005782.1 PFAM: aldo/keto reductase; KEGG: eca:ECA3293 putative oxidoreductase YP_003005783.1 PFAM: regulatory protein TetR; KEGG: eca:ECA3294 TetR family transcriptional regulator YP_003005784.1 PFAM: ApbE family lipoprotein; KEGG: eca:ECA1970 putative thiamine biosynthesis protein YP_003005785.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein; NADH:flavin oxidoreductase/NADH oxidase; KEGG: ent:Ent638_2558 flavocytochrome c YP_003005786.1 PFAM: Aldehyde Dehydrogenase; KEGG: rec:RHECIAT_PC0000919 coniferyl-aldehyde dehydrogenase protein YP_003005787.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_003005788.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: bvi:Bcep1808_7013 RNA-directed DNA polymerase (reverse transcriptase) YP_003005790.1 PFAM: protein of unknown function Spy-related; KEGG: kpe:KPK_3216 spheroplast protein Y YP_003005791.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_003005792.1 membrane protein regulates uhpT expression YP_003005793.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_003005794.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_003005795.1 KEGG: eca:ECA0656 hypothetical protein YP_003005796.1 PFAM: methyltransferase small; KEGG: eca:ECA0654 hypothetical protein YP_003005797.1 PFAM: Integral membrane protein TerC; KEGG: eca:ECA0652 hypothetical protein YP_003005798.1 KEGG: eca:ECA0648 hypothetical protein YP_003005799.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: eca:ECA0647 altronate hydrolase YP_003005800.1 catalyzes the formation of D-tagaturonate from D-altronate YP_003005801.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_003005802.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0644 galacturonate transporter YP_003005803.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_003005804.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA0642 DedA family membrane protein YP_003005805.1 KEGG: eca:ECA0641 hypothetical protein YP_003005806.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: eca:ECA0639 hypothetical protein YP_003005807.1 KEGG: ypi:YpsIP31758_0482 hypothetical protein YP_003005808.1 KEGG: yen:YE3717 hypothetical protein YP_003005809.1 PFAM: DoxX family protein; KEGG: eca:ECA0636 hypothetical protein YP_003005810.1 PFAM: Glutathione S-transferase domain; KEGG: eca:ECA0635 hypothetical protein YP_003005811.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0634 LysR family transcriptional regulator YP_003005812.1 PFAM: Pirin domain protein; KEGG: eca:ECA0633 hypothetical protein YP_003005813.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_003005814.1 Represses a number of genes involved in the response to DNA damage YP_003005815.1 PFAM: diacylglycerol kinase; KEGG: eca:ECA0629 diacylglycerol kinase YP_003005816.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_003005817.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_003005818.1 PFAM: Chorismate lyase; KEGG: eca:ECA0626 chorismate pyruvate lyase YP_003005819.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: kpe:KPK_5137 chaperonin GroL YP_003005820.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_003005821.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: spe:Spro_0407 FxsA cytoplasmic membrane protein YP_003005822.1 catalyzes the formation of fumarate from aspartate YP_003005823.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_003005824.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_003005825.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_003005826.1 PFAM: regulatory protein TetR; KEGG: yps:YPTB0395 putative transcriptional regulator YP_003005827.1 PFAM: integrase family protein; KEGG: stt:t4371 bacteriophage integrase YP_003005828.1 KEGG: ecq:ECED1_1795 conserved hypothetical protein; possible repressor (interpro) YP_003005829.1 KEGG: yen:YE3495A hypothetical protein YP_003005830.1 KEGG: eum:ECUMN_2300 putative MobC mobilization protein YP_003005831.1 PFAM: Post-segregation antitoxin CcdA; KEGG: eca:ECA0511 plasmid maintenance protein CcdA YP_003005832.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_003005833.1 PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: abc:ACICU_00863 site-specific DNA methylase YP_003005834.1 SMART: AAA ATPase; KEGG: psa:PST_3231 hypothetical protein YP_003005835.1 PFAM: GCN5-related N-acetyltransferase; KEGG: stt:t4359 hypothetical protein YP_003005836.1 PFAM: Protein of unknown function DUF1778; KEGG: eca:ECA0958 hypothetical protein YP_003005837.1 KEGG: eca:ECA0510 putative capsular polysacharide biosynthesis transferase YP_003005838.1 KEGG: eca:ECA0509 hypothetical protein YP_003005839.1 KEGG: eca:ECA0508 hypothetical protein YP_003005840.1 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: eca:ECA0507 putative capsular polysaccharide bisynthesis glycosyl transferase YP_003005841.1 PFAM: glycosyl transferase group 1; KEGG: eca:ECA0506 capsular polysaccharide bisynthesis glycosyl transferase YP_003005842.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA0505 capsular polysaccharide bisynthesis glycosyl transferase YP_003005843.1 KEGG: eca:ECA0504 putative capsular polysaccharide bisynthesis protein YP_003005844.1 KEGG: eca:ECA0503 putative capsular polysaccharide bisynthesis protein YP_003005845.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA0502 putative capsulatr polysaccharide biosynthesis protein YP_003005846.1 PFAM: polysaccharide export protein; KEGG: eca:ECA0501 putative capsular polysaccharide export protein YP_003005847.1 KEGG: eca:ECA0500 putative capsular polysaccharide biosynthesis protein YP_003005848.1 KEGG: eca:ECA0499 putative capsular polysaccharide biosynthesis protein; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase YP_003005849.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: efe:EFER_1473 putative mandelate racemase YP_003005850.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: ses:SARI_03945 hypothetical protein YP_003005851.1 KEGG: bmn:BMA10247_3037 MerR family transcriptional regulator; TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR YP_003005852.1 TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: bxe:Bxe_A4439 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_003005853.1 PFAM: monooxygenase FAD-binding; KEGG: kpn:KPN_01663 putative flavoprotein monooxygenase YP_003005854.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: eta:ETA_33390 vanillate O-demethylase oxidoreductase YP_003005855.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: kpe:KPK_2713 Rieske 2Fe-2S domain protein YP_003005856.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eta:ETA_33420 putative transcriptional regulator YP_003005857.1 TIGRFAM: OHCU decarboxylase; KEGG: kpn:KPN_01665 hypothetical protein YP_003005858.1 TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: eta:ETA_26140 transthyretin family protein YP_003005859.1 TIGRFAM: phosphonate metabolim protein, transferase hexapeptide repeat family; KEGG: bja:blr7948 acetyltransferase YP_003005860.1 PFAM: Domain of unknown function DUF1868; KEGG: ccs:CCNA_01868 hypothetical protein YP_003005861.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: eca:ECA3941 alkyl hydroperoxide reductase subunit F YP_003005862.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_003005863.1 PFAM: transport system permease protein; KEGG: cko:CKO_00852 hypothetical protein YP_003005864.1 PFAM: periplasmic binding protein; KEGG: cko:CKO_00919 hypothetical protein YP_003005865.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA4254 putative iron(III) ABC transporter ATP-binding protein YP_003005866.1 KEGG: spe:Spro_3158 hypothetical protein YP_003005867.1 SMART: metal-dependent phosphohydrolase HD region; KEGG: spe:Spro_0128 metal dependent phosphohydrolase YP_003005868.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA1683 methyl-accepting chemotaxis protein YP_003005869.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: aca:ACP_2417 oxidoreductase, short-chain dehydrogenase/reductase family YP_003005870.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: eca:ECA0474 enterobactin synthetase component D (4'-phosphopantetheinyl transferase) YP_003005871.1 PFAM: TatD-related deoxyribonuclease; KEGG: eca:ECA0472 TatD family deoxyribonuclease YP_003005872.1 KEGG: eca:ECA0471 hypothetical protein YP_003005873.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: eca:ECA0469 periplasmic protein YP_003005874.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: spe:Spro_0652 peptide chain release factor 3 YP_003005875.1 KEGG: eca:ECA0466 hypothetical protein YP_003005876.1 catalyzes the formation of serine from O-phosphoserine YP_003005877.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_003005878.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_003005879.1 TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: eca:ECA0462 putative 5-formyltetrahydrofolate cyclo-ligase YP_003005880.1 PFAM: protein of unknown function DUF710; KEGG: yen:YE3398 Z-ring-associated protein YP_003005881.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_003005882.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_003005883.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_003005884.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: eca:ECA0457 hypothetical protein YP_003005885.1 KEGG: ecm:EcSMS35_A0112 colicin-M immunity protein Cmi YP_003005886.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SM_b20079 putative hemolysin-adenlyate cyclase protein YP_003005889.1 KEGG: ypi:YpsIP31758_2860 hypothetical protein YP_003005890.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0448 putative ABC transporter extracellular solute binding protein YP_003005891.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0447 ABC transporter permease protein YP_003005892.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0446 ABC transporter permease protein YP_003005893.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: eca:ECA0445 ABC transporter ATP binding protein YP_003005894.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA0442 L-rhamnose operon transcriptional activator YP_003005895.1 activates the expression of the rhaBAD operon and rhaT gene YP_003005896.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_003005897.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_003005898.1 KEGG: eca:ECA0438 rhamnulose-1-phosphate aldolase; TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein YP_003005899.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: ecl:EcolC_4116 L-rhamnose 1-epimerase YP_003005900.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA0436 methyl-accepting chemotaxis protein YP_003005901.1 PFAM: Transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: seg:SG3764 putative transcriptional regulator YP_003005902.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: plu:plu0518 hypothetical protein YP_003005903.1 PFAM: major facilitator superfamily MFS_1; KEGG: pmr:PMI3395 MFS-family transporter YP_003005904.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: spe:Spro_1811 TrkH family potassium uptake protein YP_003005905.1 catalyzes the interconversion of chorismate to prephenate YP_003005906.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: rso:RS05577 transcription regulator protein YP_003005907.1 KEGG: aca:ACP_3248 hypothetical protein YP_003005908.1 KEGG: plu:plu3301 hypothetical protein YP_003005909.1 PFAM: SMC domain protein; KEGG: plu:plu3302 hypothetical protein YP_003005910.1 catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate YP_003005911.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2075 LysR family transcriptional regulator YP_003005912.1 PFAM: peptidase M20; KEGG: bcm:Bcenmc03_1567 peptidase M20 YP_003005913.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: vei:Veis_4730 ABC transporter related YP_003005914.1 KEGG: vei:Veis_4731 oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_003005915.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_3822 binding-protein-dependent transport systems inner membrane component YP_003005916.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_3823 binding-protein-dependent transport systems inner membrane component YP_003005917.1 PFAM: extracellular solute-binding protein family 5; KEGG: vei:Veis_4734 extracellular solute-binding protein YP_003005918.1 PFAM: delta-endotoxin CytB; KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_003005919.1 KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_003005920.1 KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_003005921.1 KEGG: asa:ASA_2128 cytolytic delta-endotoxin (insecticidal protein) YP_003005922.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpe:KPK_3986 oxidoreductase, short chain dehydrogenase/reductase family YP_003005923.1 PFAM: carbohydrate kinase FGGY; KEGG: kpe:KPK_3981 putative glycerol kinase YP_003005924.1 PFAM: inner-membrane translocator; KEGG: efe:EFER_2521 putative transport system permease for a carbohydrate-related molecule YP_003005925.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: efe:EFER_2520 putative transport system ATP-binding protein for a carbohydrate-related molecule YP_003005926.1 KEGG: efe:EFER_2519 putative lipoprotein YP_003005927.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: kpe:KPK_3982 sugar ABC transporter, periplasmic sugar-binding protein YP_003005928.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bov:BOV_1573 short chain dehydrogenase YP_003005929.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: ypg:YpAngola_A0910 putative transketolase, C-terminal subunit YP_003005930.1 PFAM: Transketolase domain protein; KEGG: pst:PSPTO_2401 transketolase, N-terminal subunit YP_003005931.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: sml:Smlt4437 putative aga operon DeoR family transcriptional repressor YP_003005932.1 PFAM: SMC domain protein; KEGG: hch:HCH_03469 ATPase YP_003005933.1 KEGG: rru:Rru_A3750 hypothetical protein YP_003005934.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_2121 major facilitator transporter YP_003005935.1 KEGG: eca:ECA0432 hypothetical protein YP_003005936.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: msu:MS2252 hypothetical protein YP_003005937.1 PFAM: major facilitator superfamily MFS_1; KEGG: bar:GBAA2480 ABC transporter permease YP_003005940.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: rso:RS03119 putative transmembrane protein YP_003005941.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_003005942.1 KEGG: pfl:PFL_4989 lysine N6-hydroxylase/L-ornithine N5-oxygenase family protein YP_003005943.1 KEGG: rso:RS03116 hypothetical protein YP_003005944.1 PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: esa:ESA_03980 hypothetical protein YP_003005945.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ypi:YpsIP31758_2079 alpha/beta hydrolase domain-containing protein YP_003005946.1 KEGG: esa:ESA_03981 hypothetical protein YP_003005947.1 PFAM: FAD dependent oxidoreductase; KEGG: rso:RS03111 putative oxidoreductase signal peptide protein YP_003005948.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: rso:RS03110 hypothetical protein YP_003005949.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS03108 hypothetical protein YP_003005950.1 KEGG: rso:RS03107 putative transmembrane protein YP_003005951.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rso:RS03106 putative acetyltransferase protein YP_003005952.1 KEGG: rso:RS03105 hypothetical protein YP_003005953.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_003005955.1 KEGG: eca:ECA0829 hypothetical protein YP_003005956.1 KEGG: efe:EFER_3104 putative 5-methylcytosine restriction system component YP_003005957.1 PFAM: ATPase associated with various cellular activities AAA_5; KEGG: efe:EFER_3105 putative 5-methylcytosine-specific restriction enzyme with GTPase activity YP_003005958.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities YP_003005959.1 PFAM: N-6 DNA methylase; putative RNA methylase; KEGG: maq:Maqu_0031 N-6 DNA methylase YP_003005960.1 PFAM: restriction modification system DNA specificity domain; KEGG: stm:STM4524 type I restriction enzyme specificity protein YP_003005961.1 KEGG: eca:ECA0128 hypothetical protein YP_003005962.1 KEGG: sbl:Sbal_4387 hypothetical protein YP_003005963.1 PFAM: Pirin domain protein; KEGG: pzu:PHZ_c1158 pirin-related protein YP_003005964.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ara:Arad_4435 transporter YP_003005966.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppw:PputW619_2824 LysR family transcriptional regulator YP_003005967.1 PFAM: PilT protein domain protein; KEGG: eca:ECA2850 putative plasmid protein YP_003005968.1 KEGG: eca:ECA2851 putative plasmid protein YP_003005969.1 PFAM: Patatin; KEGG: eck:EC55989_2255 hypothetical protein YP_003005970.1 KEGG: ecz:ECS88_2093 hypothetical protein YP_003005971.1 KEGG: ecp:ECP_2038 hypothetical protein YP_003005972.1 PFAM: Insertion element protein; KEGG: ecz:ECS88_4707 transposase InsA (ORF1) IS1 YP_003005975.1 PFAM: protein of unknown function DUF1219; KEGG: eca:ECA2853 hypothetical protein YP_003005976.1 KEGG: plu:plu4325 hypothetical protein YP_003005977.1 PFAM: protein of unknown function DUF87; KEGG: pst:PSPTO_4332 hypothetical protein YP_003005978.1 KEGG: pst:PSPTO_4326 hypothetical protein YP_003005979.1 SMART: helix-turn-helix domain protein; KEGG: plu:plu4466 hypothetical protein YP_003005980.1 PFAM: protein of unknown function DUF1044; KEGG: plu:plu4467 hypothetical protein YP_003005981.1 PFAM: Prophage CP4-57 regulatory; KEGG: ypg:YpAngola_A1363 AlpA family transcriptional regulator YP_003005982.1 KEGG: ypp:YPDSF_2605 prophage protein YP_003005983.1 PFAM: P4 alpha zinc-binding domain protein; TOPRIM domain protein; SMART: P4 alpha zinc-binding domain protein; Toprim sub domain protein; KEGG: plu:plu4471 hypothetical protein YP_003005984.1 TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: sea:SeAg_B4814 protein HipA YP_003005985.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sea:SeAg_B4813 putative transcriptionl regulator HipB YP_003005986.1 PFAM: integrase family protein; KEGG: plu:plu4477 hypothetical protein YP_003005987.1 PFAM: Protein of unknown function DUF1778; KEGG: ecf:ECH74115_4726 hypothetical protein YP_003005988.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ecf:ECH74115_4727 acetyltransferase, GNAT family YP_003005989.1 KEGG: plu:plu4474 hypothetical protein YP_003005990.1 PFAM: P4 alpha zinc-binding domain protein; TOPRIM domain protein; SMART: P4 alpha zinc-binding domain protein; Toprim sub domain protein; KEGG: plu:plu4471 hypothetical protein YP_003005991.1 KEGG: ypp:YPDSF_2605 prophage protein YP_003005992.1 PFAM: Prophage CP4-57 regulatory; KEGG: ypn:YPN_2905 transcriptional regulator YP_003005993.1 KEGG: plu:plu4470 hypothetical protein YP_003005995.1 KEGG: see:SNSL254_A2838 hypothetical protein YP_003005996.1 KEGG: pmr:PMI0516 hypothetical protein YP_003005997.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: see:SNSL254_A2836 chromosome partitioning ATPase YP_003005999.1 PFAM: integrase family protein; KEGG: see:SNSL254_A4836 integrase YP_003006000.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sgl:SG2107 putative transport protein YP_003006001.1 PFAM: permease YjgP/YjgQ family protein; KEGG: eca:ECA0405 putative permease YP_003006002.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_003006003.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_003006004.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_003006005.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0390 methyl-accepting chemotaxis protein YP_003006006.1 PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA0389 hypothetical protein YP_003006007.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pzu:PHZ_c0633 acetyltransferase, GNAT family YP_003006008.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; KEGG: spe:Spro_1454 XRE family transcriptional regulator YP_003006009.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0386 putative acetyltransferase YP_003006010.1 KEGG: pfo:Pfl01_2665 hypothetical protein YP_003006011.1 PFAM: protein of unknown function DUF29; KEGG: plu:plu4118 hypothetical protein YP_003006012.1 PFAM: protein of unknown function DUF1260; KEGG: eca:ECA0385 hypothetical protein YP_003006013.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_003006014.1 PFAM: glycoside hydrolase family 1; KEGG: vsp:VS_II0097 6-phospho-beta-glucosidase YP_003006015.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA0383 hypothetical protein YP_003006016.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_003006017.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_003006018.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: yen:YE3768 hypothetical protein YP_003006020.1 PFAM: Amidase; KEGG: bph:Bphy_7768 amidase YP_003006021.1 PFAM: amine oxidase; KEGG: bph:Bphy_7769 amine oxidase YP_003006022.1 KEGG: pmy:Pmen_0112 hypothetical protein YP_003006023.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eta:ETA_23880 putative ATP-binding component of ABC transporter YP_003006024.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eta:ETA_23890 ABC-type dipeptide/oligopeptide/nickel transport systems, permease component YP_003006025.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eta:ETA_23900 ABC-type dipeptide/oligopeptide/nickel transport systems, permease component YP_003006026.1 PFAM: extracellular solute-binding protein family 5; KEGG: eta:ETA_23910 ABC-type dipeptide transport system, periplasmic component (OphA), DdpA region YP_003006027.1 PFAM: homocysteine S-methyltransferase; KEGG: eta:ETA_23920 homocysteine S-methyltransferase family protein YP_003006028.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_003006029.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; KEGG: stt:t4485 anaerobic ribonucleotide reductase-activating protein YP_003006030.1 KEGG: eca:ECA0372 hypothetical protein YP_003006031.1 KEGG: ppu:PP_4152 hypothetical protein YP_003006032.1 TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; KEGG: plu:plu2268 hypothetical protein YP_003006033.1 TIGRFAM: CRISPR-associated protein, Cse1 family; KEGG: sew:SeSA_A3097 crispr-associated protein, CSE1 family YP_003006034.1 PFAM: PfkB domain protein; KEGG: eca:ECA0364 aminoimidazole riboside kinase YP_003006035.1 PFAM: porin LamB type; KEGG: eca:ECA0363 putative sucrose porin YP_003006036.1 TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PTS system, maltose and glucose-specific subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: eca:ECA0362 PTS system, sucrose-specific IIBC component YP_003006037.1 KEGG: eca:ECA0361 sucrose-6-phosphate hydrolase; TIGRFAM: sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32 YP_003006038.1 KEGG: eca:ECA0360 sucrose operon repressor; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI YP_003006039.1 TIGRFAM: TonB system transport protein ExbD; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: eca:ECA0359 biopolymer transport protein ExbD YP_003006040.1 TIGRFAM: tonB-system energizer ExbB; PFAM: MotA/TolQ/ExbB proton channel; KEGG: eca:ECA0358 biopolymer transport protein YP_003006041.1 catalyzes the formation of L-homocysteine from cystathionine YP_003006042.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA0353 DedA family membrane protein YP_003006043.1 PFAM: AraC-type transcriptional regulator domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: spe:Spro_4214 AraC family transcriptional regulator YP_003006044.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: spe:Spro_4215 iron-containing alcohol dehydrogenase YP_003006045.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_003006046.1 PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: eca:ECA0347 repressor protein for FtsI YP_003006047.1 KEGG: eca:ECA0346 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase YP_003006048.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003006049.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: eca:ECA0337 putative modulator of drug activity B YP_003006050.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0336 LysR family transcriptional regulator YP_003006051.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003006052.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_003006053.1 PFAM: Calcineurin phosphoesterase domain protein; metallophosphoesterase; KEGG: eca:ECA0333 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_003006054.1 PFAM: protein of unknown function DUF1249; KEGG: spe:Spro_4266 hypothetical protein YP_003006055.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_003006056.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_003006057.1 PFAM: protein of unknown function DUF1190; KEGG: eca:ECA0329 hypothetical protein YP_003006058.1 PFAM: glutathionylspermidine synthase; KEGG: eca:ECA0328 putative glutathionylspermidine synthase YP_003006059.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_003006060.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA0323 putative tetrapyrrole methylase YP_003006061.1 PFAM: LppC family lipoprotein; KEGG: eca:ECA0322 hypothetical protein YP_003006062.1 PFAM: protein of unknown function UPF0102; KEGG: ypi:YpsIP31758_0474 hypothetical protein YP_003006063.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_003006064.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: eca:ECA0319 hypothetical protein YP_003006065.1 KEGG: eca:ECA0318 hypothetical protein YP_003006066.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_003006067.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA0316 isoprenoid biosynthesis protein YP_003006068.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_003006069.1 KEGG: eca:ECA0313 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_003006070.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_003006071.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_003006072.1 PFAM: transposase IS4 family protein; KEGG: sfx:S4808 hypothetical protein YP_003006073.1 PFAM: Stringent starvation protein B; KEGG: efe:EFER_3198 ClpXP protease specificity-enhancing factor YP_003006074.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_003006075.1 PFAM: ribosomal protein S9; KEGG: eca:ECA0307 30S ribosomal protein S9 YP_003006076.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_003006077.1 PFAM: AFG1-family ATPase; KEGG: eca:ECA0305 putative ATP/GTP-binding protein YP_003006078.1 PFAM: protein of unknown function DUF1043; KEGG: eca:ECA0304 cytochrome d ubiquinol oxidase subunit III YP_003006079.1 KEGG: eca:ECA0303 exported protease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein YP_003006080.1 KEGG: sgl:SG0212 serine endoprotease; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein YP_003006081.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_003006082.1 PFAM: BolA family protein; KEGG: spe:Spro_4355 BolA family protein YP_003006083.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: yen:YE3748 putative anti-sigma B factor antagonist YP_003006084.1 PFAM: toluene tolerance family protein; KEGG: spe:Spro_4357 toluene tolerance family protein YP_003006085.1 PFAM: Mammalian cell entry related domain protein; KEGG: eca:ECA0297 hypothetical protein YP_003006086.1 PFAM: protein of unknown function DUF140; KEGG: yen:YE3751 hypothetical protein YP_003006087.1 ATP-binding subunit of a putative ABC toluene efflux transporter YP_003006088.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_003006089.1 KEGG: eca:ECA0293 D-arabinose 5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein YP_003006090.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_003006091.1 PFAM: protein of unknown function DUF1239; KEGG: spe:Spro_4364 hypothetical protein YP_003006092.1 TIGRFAM: lipopolysaccharide transport periplasmic protein LptA; PFAM: OstA family protein; KEGG: efe:EFER_3177 putative lipopolysaccharide transport protein A: periplasmic-binding component of ABC superfamily YP_003006093.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0289 putative ABC transporter ATP-binding protein YhbG YP_003006094.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_003006095.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: yen:YE3760 putative sigma(54) modulation protein YP_003006096.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: eca:ECA0286 sugar-specific enzyme IIA component of PTS YP_003006097.1 PFAM: conserved hypothetical protein; KEGG: eta:ETA_03120 conserved hypothetical protein YhbJ YP_003006098.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: eca:ECA0284 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_003006099.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_003006100.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_003006101.1 PFAM: protein of unknown function DUF615; KEGG: eca:ECA0281 hypothetical protein YP_003006103.1 PFAM: protein of unknown function DUF1543; KEGG: sgl:SG0708 hypothetical protein YP_003006104.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_003006105.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_003006106.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_003006107.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0276 putative DNA-binding transcriptional regulator YP_003006108.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_003006109.1 KEGG: eca:ECA0272 hypothetical protein YP_003006110.1 involved in the processing of the 5'end of 16S rRNA YP_003006111.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: ypi:YpsIP31758_0401 Maf-like protein YP_003006112.1 part of cell wall structural complex MreBCD; transmembrane component YP_003006113.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_003006114.1 functions in MreBCD complex in some organisms YP_003006115.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_003006116.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA0265 putative zinc-binding oxidoreductase YP_003006117.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_003006118.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_003006119.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_003006120.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: eca:ECA0261 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_003006121.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: eca:ECA0260 acetyl-CoA carboxylase biotin carboxylase subunit YP_003006122.1 PFAM: protein of unknown function DUF997; KEGG: esa:ESA_03646 hypothetical protein YP_003006123.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_003006124.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_003006125.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: eca:ECA0256 tRNA-dihydrouridine synthase B YP_003006126.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_003006127.1 PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: yen:YE3722 NADP-dependent alcohol dehydrogenase YP_003006128.1 KEGG: ade:Adeh_3217 short-chain dehydrogenase/reductase SDR YP_003006129.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: spe:Spro_3098 cupin 2 domain-containing protein YP_003006130.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3134 LysR family transcriptional regulator YP_003006131.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ara:Arad_7425 drug transporter protein YP_003006133.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: eca:ECA0251 endonuclease/exonuclease/phosphatase family protein YP_003006134.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA0247 putative cystine-binding periplasmic protein YP_003006135.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0246 putative amino-acid transport system permease protein YP_003006136.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA0245 general L-amino ABC transporter binding protein YP_003006137.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0244 L-amino acid ABC transporter permease protein YP_003006138.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0243 L-amino acid ABC transporter permease protein YP_003006139.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0242 L-amino acid ABC transporter ATP-binding protein YP_003006140.1 involved in de novo purine biosynthesis YP_003006141.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_003006142.1 PFAM: protein of unknown function DUF1481; KEGG: eca:ECA0239 putative lipoprotein YP_003006143.1 histone-like DNA-binding protein YP_003006144.1 PFAM: protein of unknown function DUF416; KEGG: eca:ECA0237 putative lipoprotein YP_003006145.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_003006146.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_003006147.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_003006148.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_003006149.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_003006150.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_003006151.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spe:Spro_0282 UBA/ThiF-type NAD/FAD binding protein YP_003006152.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS YP_003006153.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_003006154.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_003006155.1 PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eta:ETA_01690 putative GntR-family transcriptional regulator YP_003006157.1 PFAM: protein of unknown function DUF1127; KEGG: ecl:EcolC_3722 hypothetical protein YP_003006158.1 PFAM: protein of unknown function DUF1127; KEGG: ecr:ECIAI1_4560 hypothetical protein YP_003006160.1 PFAM: protein of unknown function DUF1176; KEGG: bur:Bcep18194_B2472 hypothetical protein YP_003006161.1 PFAM: protein of unknown function DUF1176; KEGG: ent:Ent638_2961 hypothetical protein YP_003006163.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_003006164.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_003006165.1 TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12; KEGG: ent:Ent638_0196 50S ribosomal protein L7/L12 YP_003006166.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_003006167.1 TIGRFAM: ribosomal protein L1; PFAM: ribosomal protein L1; KEGG: kpn:KPN_04361 50S ribosomal protein L1 YP_003006168.1 KEGG: kpe:KPK_5313 ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: ribosomal protein L11; SMART: ribosomal protein L11 YP_003006169.1 Modulates Rho-dependent transcription termination YP_003006170.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_003006171.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_003006173.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_003006174.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_003006175.1 KEGG: elf:LF82_1416 hypothetical protein; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; FAD linked oxidase domain protein YP_003006176.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_003006177.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: yen:YE0272 potassium transporter YP_003006178.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: eca:ECA0210 hypothetical protein YP_003006179.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_003006180.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_003006181.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_003006182.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: ppf:Pput_2447 protein of unknown function DUF395, YeeE/YedE YP_003006183.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: spe:Spro_1878 protein of unknown function DUF395 YeeE/YedE YP_003006184.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_003006185.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: eca:ECA0205 3-octaprenyl-4-hydroxybenzoate decarboxylase YP_003006186.1 KEGG: spe:Spro_0256 transcriptional activator RfaH; TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; SMART: NGN domain protein YP_003006187.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_003006188.1 magnesium dependent; not involved in the Sec-independent protein export system YP_003006189.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_003006190.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: spe:Spro_0252 twin-arginine translocation protein, TatB subunit YP_003006191.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: eca:ECA0199 sec-independent protein translocase YP_003006192.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_003006193.1 PFAM: Sterol-binding domain protein; KEGG: eca:ECA0197 hypothetical protein YP_003006194.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA0196 ubiquinone/menaquinone biosynthesis methyltransferase YP_003006195.1 PFAM: protein of unknown function DUF195; KEGG: eca:ECA0195 DNA recombination protein YP_003006196.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_003006197.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_003006198.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_003006199.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_003006200.1 KEGG: eca:ECA2020 hypothetical protein YP_003006201.1 KEGG: eca:ECA2019 hypothetical protein YP_003006204.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hypothetical protein YP_003006205.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: pmr:PMI2779 thiamine biosynthesis adenylyltransferase YP_003006206.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: asu:Asuc_1634 ABC transporter related YP_003006207.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_003006209.1 KEGG: vei:Veis_1323 hypothetical protein YP_003006210.1 KEGG: eca:ECA0186 hypothetical protein YP_003006211.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_003006212.1 PFAM: dienelactone hydrolase; KEGG: eca:ECA0184 putative carboxymethylenebutenolidase YP_003006213.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_003006214.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0180 transcriptional activator protein YP_003006215.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA0179 hypothetical protein YP_003006216.1 PFAM: Antimicrobial peptide resistance and lipid A acylation PagP; KEGG: eca:ECA0175 palmitoyl transferase for lipid A YP_003006217.1 catalyzes the O-acetylation of serine YP_003006218.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_003006219.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_003006220.1 PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: eca:ECA0171 putative rhodanese-related sulfurtransferase YP_003006221.1 PFAM: Peptidase M23; KEGG: eca:ECA0170 hypothetical protein YP_003006222.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: eca:ECA0169 hypothetical protein YP_003006223.1 TIGRFAM: L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: pmr:PMI3178 L-threonine 3-dehydrogenase YP_003006224.1 KEGG: eca:ECA0167 2-amino-3-ketobutyrate coenzyme A ligase; TIGRFAM: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: aminotransferase class I and II YP_003006225.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_003006226.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_003006227.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: eca:ECA0163 ADP-heptose:LPS heptosyl transferase I YP_003006228.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: dar:Daro_0152 lipopolysaccharide heptosyltransferase III, putative YP_003006229.1 PFAM: glycosyl transferase group 1; KEGG: eta:ETA_00760 glycosyl transferase, group 1 YP_003006230.1 PFAM: O-antigen polymerase; KEGG: hch:HCH_01051 O-antigen polymerase YP_003006231.1 PFAM: glycosyl transferase family 9; KEGG: bxe:Bxe_A3288 putative lipopolysaccharide core biosynthesis glycosyltransferase protein YP_003006232.1 PFAM: glycosyl transferase group 1; KEGG: plu:plu4862 WalR protein YP_003006233.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_003006234.1 PFAM: glycosyl transferase family 2; KEGG: yen:YE0068 lipopolysaccharide core biosynthesis glycosyl transferase YP_003006235.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_003006236.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_003006237.1 TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: yps:YPTB0048 50S ribosomal protein L33 YP_003006238.1 required for 70S ribosome assembly YP_003006239.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_003006240.1 KEGG: spe:Spro_4843 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein YP_003006241.1 TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; KEGG: eca:ECA0143 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_003006242.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_003006243.1 KEGG: eca:ECA0141 orotate phosphoribosyltransferase; TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_003006244.1 KEGG: eca:ECA0140 ribonuclease PH; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2 YP_003006245.1 PFAM: protein of unknown function DUF202; KEGG: eca:ECA3000 hypothetical protein YP_003006246.1 KEGG: eca:ECA3001 hypothetical protein YP_003006247.1 PFAM: protein of unknown function DUF1611; KEGG: ppr:PBPRA1897 hypothetical protein YP_003006248.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0139 putative mandelate racemase / muconate lactonizing enzyme family protein YP_003006249.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: eca:ECA0138 ABC transporter ATP-binding protein YP_003006250.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0137 ABC transporter periplasmic binding protein YP_003006251.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0136 ABC transporter permease protein YP_003006252.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0135 ABC transporter permease protein YP_003006253.1 PFAM: peptidase S58 DmpA; KEGG: eca:ECA0134 putative peptidase YP_003006254.1 PFAM: peptidase M55 D-aminopeptidase; KEGG: eca:ECA0133 hypothetical protein YP_003006255.1 PFAM: peptidase T2 asparaginase 2; KEGG: eca:ECA0132 L-asparaginase YP_003006256.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA0176 hypothetical protein YP_003006257.1 KEGG: eca:ECA0177 hypothetical protein YP_003006258.1 KEGG: eta:ETA_34450 hypothetical protein YP_003006259.1 PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_01116 hypothetical protein YP_003006260.1 PFAM: outer membrane efflux protein; KEGG: plu:plu2646 hypothetical protein YP_003006261.1 PFAM: protein of unknown function DUF214; KEGG: plu:plu2647 hypothetical protein YP_003006262.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppw:PputW619_0892 ABC transporter related YP_003006263.1 KEGG: ent:Ent638_0389 hypothetical protein YP_003006264.1 KEGG: ent:Ent638_0389 hypothetical protein YP_003006265.1 KEGG: ent:Ent638_0389 hypothetical protein YP_003006266.1 KEGG: plu:plu2640 hypothetical protein YP_003006267.1 PFAM: beta-lactamase; KEGG: spe:Spro_2075 beta-lactamase YP_003006268.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_C_4567 oligopeptide transport ATP-binding protein AppF YP_003006269.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_C_4569 dipeptide transporter DppD homolog YP_003006270.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_3739 binding-protein-dependent transport systems inner membrane component YP_003006271.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_3740 binding-protein-dependent transport systems inner membrane component YP_003006272.1 PFAM: extracellular solute-binding protein family 5; KEGG: atc:AGR_C_4574 putative hemin-binding lipoprotein YP_003006273.1 PFAM: peptidase M19 renal dipeptidase; KEGG: atc:AGR_C_4575 membrane dipeptidase homolog YP_003006274.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0131 LysR family transcriptional regulator YP_003006275.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: eca:ECA0130 hypothetical protein YP_003006276.1 PFAM: integrase family protein; KEGG: sbo:SBO_3647 putative integrase YP_003006277.1 KEGG: eca:ECA2751 putative phage-related protein YP_003006278.1 PFAM: Prophage CP4-57 regulatory; KEGG: sbc:SbBS512_E4074 prophage CP4-57 transcriptional regulator protein, AlpA family YP_003006279.1 KEGG: eta:ETA_24300 hypothetical protein YP_003006280.1 PFAM: AntA/AntB antirepressor domain protein; KEGG: eta:ETA_24290 putative phage anti-repressor protein YP_003006281.1 KEGG: eca:ECA0668 hypothetical protein YP_003006283.1 KEGG: eck:EC55989_0275 hypothetical protein YP_003006284.1 KEGG: eta:ETA_24230 conserved hypothetical protein, related to bacteriophage P27 YP_003006285.1 PFAM: protein of unknown function DUF927; P4 alpha zinc-binding domain protein; SMART: P4 alpha zinc-binding domain protein; KEGG: eta:ETA_24220 putative prophage primase YP_003006286.1 KEGG: ecg:E2348C_3896 hypothetical protein YP_003006287.1 KEGG: ypi:YpsIP31758_2206 lysozyme YP_003006288.1 KEGG: eck:EC55989_2615 putative terminase small subunit YP_003006289.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003006290.1 PFAM: Abi family protein; KEGG: eba:ebA5889 hypothetical protein YP_003006292.1 PFAM: transposase IS4 family protein; KEGG: vha:VIBHAR_05087 hypothetical protein YP_003006293.1 KEGG: rlt:Rleg2_3992 hypothetical protein YP_003006294.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_003006295.1 TIGRFAM: N-carbamoylputrescine amidase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eca:ECA4274 putative carbon-nitrogen hydrolase YP_003006296.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_003006297.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_003006298.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: kpe:KPK_2763 DNA-binding protein YP_003006299.1 PFAM: NUDIX hydrolase; KEGG: sea:SeAg_B4799 NUDIX hydrolase YP_003006300.1 PFAM: tail assembly chaperone gp38; KEGG: eum:ECUMN_0911 hypothetical protein; putative phage tail fiber assembly protein YP_003006301.1 KEGG: ecz:ECS88_2817 putative variable tail fiber protein YP_003006302.1 PFAM: Tail Collar domain protein; KEGG: eta:ETA_05860 putative phage tail fiber protein YP_003006303.1 PFAM: tail assembly chaperone gp38; KEGG: plu:plu3024 hypothetical protein YP_003006304.1 PFAM: Tail Collar domain protein; KEGG: eca:ECA2608 bacteriophage variable tail fiber protein H YP_003006305.1 KEGG: sfv:SFV_0255 putative phage tail fibre protein YP_003006306.1 KEGG: eca:ECA2608 bacteriophage variable tail fiber protein H YP_003006307.1 KEGG: sfv:SFV_0255 putative phage tail fibre protein YP_003006308.1 PFAM: Tail Collar domain protein; KEGG: eca:ECA2608 bacteriophage variable tail fiber protein H YP_003006309.1 KEGG: eca:ECA4310 putative stress resistance protein YP_003006310.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_003006311.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_003006312.1 KEGG: eca:ECA4313 hypothetical protein YP_003006313.1 KEGG: eca:ECA4314 hypothetical protein YP_003006314.1 KEGG: bam:Bamb_5223 hypothetical protein YP_003006315.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: eca:ECA4315 putative RNA-methyltransferase YP_003006316.1 KEGG: eca:ECA4316 hypothetical protein YP_003006317.1 PFAM: Auxin Efflux Carrier; KEGG: eca:ECA4317 putative transporter YP_003006318.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_003006319.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_003006320.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_003006321.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_003006322.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_003006323.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4332 methyl-accepting chemotaxis protein YP_003006324.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4335 methyl-accepting chemotaxis protein YP_003006325.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4335 methyl-accepting chemotaxis protein YP_003006326.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: plu:plu0404 hypothetical protein YP_003006327.1 KEGG: sek:SSPA2223 probable secreted protein YP_003006328.1 PFAM: Peptidoglycan-binding domain 1 protein; glycoside hydrolase family 24; KEGG: btr:Btr_0306 phage-related lysozyme YP_003006329.1 KEGG: rru:Rru_A0564 hypothetical protein YP_003006330.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: aav:Aave_4495 methyl-accepting chemotaxis sensory transducer YP_003006331.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA4336 putative aminotransferase YP_003006332.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003006333.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003006334.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003006335.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_003006336.1 PFAM: Extracellular ligand-binding receptor; KEGG: eca:ECA4341 leucine-specific binding protein YP_003006337.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4342 putative acetyltransferase YP_003006339.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_003006340.1 putative ABC transporter, membrane protein YP_003006341.1 KEGG: sgl:SG0085 cell division protein FtsE; TIGRFAM: Type II (General) Secretory Pathway (IISP) Family protein; cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_003006342.1 KEGG: eca:ECA4346 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_003006343.1 catalyzes the methylation of 16S rRNA at position G966 YP_003006344.1 PFAM: protein of unknown function DUF1145; KEGG: eca:ECA4348 hypothetical protein YP_003006345.1 PFAM: Domain of unknown function DUF1820; KEGG: eca:ECA4350 hypothetical protein YP_003006346.1 PFAM: SirA family protein; KEGG: eca:ECA4353 cell developmental protein SirA YP_003006347.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: eca:ECA4354 hypothetical protein YP_003006348.1 KEGG: eca:ECA4355 hypothetical protein YP_003006349.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4358 hypothetical protein YP_003006350.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: eca:ECA4359 hypothetical protein YP_003006351.1 TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: yps:YPTB3829 tautomerase enzyme YP_003006352.1 PFAM: PfkB domain protein; KEGG: eca:ECA4360 2-dehydro-3-deoxygluconokinase YP_003006353.1 KEGG: ecm:EcSMS35_4765 hypothetical protein YP_003006354.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA4361 putative peptidase YP_003006355.1 involved in the transport of C4-dicarboxylates across the membrane YP_003006356.1 PFAM: glycoside hydrolase family 8; KEGG: eta:ETA_33880 minor endoglucanase Y precursor (endo-1,4-beta-glucanase Y) YP_003006357.1 KEGG: eta:ETA_33890 cellulose synthase operon protein D YP_003006358.1 PFAM: cellulose synthase operon C domain protein; Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein; KEGG: eta:ETA_33900 cellulose synthase operon protein C YP_003006359.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_003006360.1 TIGRFAM: cellulose synthase catalytic subunit (UDP-forming); PFAM: glycosyl transferase family 2; type IV pilus assembly PilZ; KEGG: eta:ETA_33920 cellulose synthase, cellulose synthase operon protein A YP_003006361.1 TIGRFAM: cellulose synthase operon protein YhjQ; KEGG: ent:Ent638_3941 hypothetical protein YP_003006362.1 KEGG: eta:ETA_33940 hypothetical protein YP_003006363.1 KEGG: spe:Spro_4310 helix-turn-helix domain-containing protein YP_003006364.1 KEGG: plu:plu4519 IS427 family transposase YP_003006366.1 KEGG: spe:Spro_4311 HipA domain-containing protein YP_003006367.1 KEGG: yps:YPTB1848 hypothetical protein YP_003006369.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA1069 hypothetical protein YP_003006370.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_003006371.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_003006372.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4392 dipeptide transporter YP_003006373.1 transports peptides consisting of two or three amino acids YP_003006374.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4394 periplasmic dipeptide transport protein YP_003006375.1 PFAM: Citrate carrier protein; KEGG: eca:ECA4395 Na(+)-malate symporter YP_003006376.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: bvi:Bcep1808_7013 RNA-directed DNA polymerase (reverse transcriptase) YP_003006377.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_003006378.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_003006379.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: eca:ECA4400 putative sodium:sulfate symporter YP_003006380.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_003006381.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_003006382.1 PFAM: protein of unknown function DUF1375; KEGG: eca:ECA4404 hypothetical protein YP_003006383.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sed:SeD_A0233 major facilitator family transporter YP_003006384.1 KEGG: eca:ECA4405 hypothetical protein YP_003006385.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA4406 hypothetical protein YP_003006386.1 PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; KEGG: csa:Csal_1739 transcriptional regulator, GntR family YP_003006387.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_003006388.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_003006389.1 PFAM: UspA domain protein; KEGG: eca:ECA0050 universal stress protein A YP_003006391.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_003006392.1 PFAM: phosphate transporter; KEGG: eca:ECA0048 low-affinity inorganic phosphate transporter YP_003006393.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: spe:Spro_4688 hypothetical protein YP_003006394.1 PFAM: SMC domain protein; SMART: AAA ATPase; KEGG: ecm:EcSMS35_2489 SMC domain protein YP_003006395.1 KEGG: ecm:EcSMS35_2490 hypothetical protein YP_003006396.1 PFAM: protein of unknown function DUF1471; KEGG: plu:plu4502 hypothetical protein YP_003006397.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mlo:mll3063 hypothetical protein YP_003006398.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: avi:Avi_5254 ABC transporter nucleotide binding/ATPase protein (sugar) YP_003006399.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_1293 sugar ABC transporter, permease protein YP_003006400.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: avi:Avi_5252 ABC transporter membrane spanning protein (sugar) YP_003006401.1 PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_1296 putative multiple sugar transport system substrate-binding protein YP_003006402.1 PFAM: ROK family protein; KEGG: avi:Avi_5249 transcriptional regulator ROK family YP_003006403.1 PFAM: protein of unknown function DUF1471; KEGG: plu:plu4502 hypothetical protein YP_003006404.1 TIGRFAM: D-serine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bvi:Bcep1808_3327 D-serine dehydratase YP_003006405.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vvu:VV1_2510 putative acetyltransferase YP_003006406.1 KEGG: dac:Daci_1101 bile acid:sodium symporter YP_003006407.1 KEGG: cak:Caul_4076 phosphotransferase domain-containing protein YP_003006408.1 PFAM: extracellular solute-binding protein family 1; KEGG: dsh:Dshi_2014 extracellular solute-binding protein YP_003006409.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_0260 sugar ABC transporter permease YP_003006410.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_pAT_78 probable binding protein dependent transport protein YP_003006411.1 PFAM: histidine acid phosphatase; KEGG: eca:ECA4198 putative exported phosphatase YP_003006412.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3375 transporter YP_003006413.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3376 LysR family transcriptional regulator YP_003006414.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3953 transporter YP_003006415.1 KEGG: aha:AHA_3219 long-chain acyl-CoA synthetase YP_003006416.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: asa:ASA_1093 short chain dehydrogenase YP_003006417.1 KEGG: aha:AHA_3221 TPR repeat-containing protein YP_003006418.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_003006419.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_003006420.1 Essential for recycling GMP and indirectly, cGMP YP_003006421.1 TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; KEGG: eca:ECA0039 DNA-directed RNA polymerase subunit omega YP_003006422.1 KEGG: eca:ECA0038 bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; amino acid-binding ACT domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_003006423.1 specifically modifies tRNA at position G18 YP_003006424.1 catalyzes branch migration in Holliday junction intermediates YP_003006425.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: eta:ETA_00380 putative purine/xanthine transport protein YP_003006426.1 PFAM: AsmA family protein; KEGG: eca:ECA0034 hypothetical protein YP_003006427.1 TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0033 GNAT family acetyltransferase YP_003006428.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_003006429.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA0031 phosphatase YP_003006430.1 TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: eum:ECUMN_4395 GTP-binding protein YP_003006431.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_003006433.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_003006434.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_003006436.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003006437.1 PFAM: protein of unknown function DUF414; KEGG: eca:ECA0024 hypothetical protein YP_003006438.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_003006439.1 KEGG: eca:ECA0021 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; 3'-5' exonuclease; Helix-hairpin-helix domain protein class 2 YP_003006440.1 PFAM: DSBA oxidoreductase; KEGG: eca:ECA0020 periplasmic protein disulfide isomerase I YP_003006441.1 PFAM: aminoglycoside phosphotransferase; KEGG: spe:Spro_4890 serine/threonine protein kinase YP_003006442.1 PFAM: protein of unknown function DUF1040; KEGG: eca:ECA0018 hypothetical protein YP_003006443.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_003006444.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: spe:Spro_4893 molybdopterin-guanine dinucleotide biosynthesis protein B YP_003006445.1 DNA-binding transcriptional repressor of ribose metabolism YP_003006446.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_003006447.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_003006448.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_003006449.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_003006450.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_003006451.1 PFAM: conserved hypothetical protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: cko:CKO_04413 hypothetical protein YP_003006452.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: eca:ECA0008 two-component system response regulator YP_003006453.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA0007 sensor protein QseC YP_003006454.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_003006455.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_003006456.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_003006457.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_003006458.1 PFAM: flavodoxin/nitric oxide synthase; KEGG: eca:ECA0001 flavodoxin YP_003006459.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_003006460.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: yen:YE4214 glucose-inhibited division protein B YP_003006462.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_003006463.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_003006464.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_003006465.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_003006466.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_003006467.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_003006468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_003006469.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_003006470.1 TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: H+transporting two-sector ATPase delta/epsilon subunit; KEGG: eca:ECA4511 F0F1 ATP synthase subunit epsilon YP_003006471.1 KEGG: eca:ECA4510 exopolygalacturonate lyase YP_003006472.1 KEGG: spe:Spro_0010 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_003006473.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_003006474.1 PFAM: transposase IS3/IS911 family protein; KEGG: eci:UTI89_C4918 hypothetical protein YP_003006475.1 KEGG: slo:Shew_3662 hypothetical protein YP_003006476.1 KEGG: eca:ECA3625 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein YP_003006477.1 KEGG: rru:Rru_A2993 hypothetical protein YP_003006478.1 KEGG: rru:Rru_A2994 hypothetical protein YP_003006479.1 KEGG: rru:Rru_A2995 hypothetical protein YP_003006480.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA4477 phosphate transporter subunit YP_003006481.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_003006482.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_003006483.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_003006484.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_003006485.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4470 extracellular solute-binding protein YP_003006486.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4468 binding-protein-dependent transport system inner membrane component YP_003006487.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA4467 binding-protein-dependent transport system inner membrane component YP_003006488.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_003006489.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: eca:ECA4464 putative permease YP_003006490.1 KEGG: eca:ECA4463 hypothetical protein YP_003006491.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA4462 electron transport protein YP_003006492.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_003006493.1 PFAM: Curli production assembly/transport component CsgG; KEGG: eca:ECA4460 putative lipoprotein YP_003006494.1 KEGG: eca:ECA4459 putative lipoprotein YP_003006495.1 PFAM: protein of unknown function DUF799; KEGG: eca:ECA4458 putative lipoprotein YP_003006496.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_003006497.1 PFAM: glycosyl transferase family 2; KEGG: sgl:SG1844 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_003006498.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_003006499.1 PFAM: polysaccharide deacetylase; KEGG: ent:Ent638_2076 polysaccharide deacetylase YP_003006500.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_003006501.1 KEGG: eta:ETA_23780 putative inner membrane protein YP_003006502.1 KEGG: ent:Ent638_2073 hypothetical protein YP_003006503.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eta:ETA_17400 putative GNAT-family acetyltransferase YP_003006504.1 KEGG: atc:AGR_C_3633 conserved hypothetical protein PA0741 YP_003006505.1 PFAM: helix-turn-helix HxlR type; KEGG: atc:AGR_C_3635 hypothetical protein YP_003006506.1 KEGG: dac:Daci_4795 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_003006507.1 KEGG: pfo:Pfl01_2954 beta-lactamase-like YP_003006508.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: eca:ECA2247 AraC family transcription regulator YP_003006509.1 KEGG: neu:NE2494 hypothetical protein YP_003006510.1 KEGG: neu:NE2495 ABC transporter YP_003006511.1 KEGG: neu:NE2496 restriction modification system, type I YP_003006512.1 PFAM: N-6 DNA methylase; putative RNA methylase; KEGG: neu:NE2497 type I restriction modification enzyme methylase subunit YP_003006513.1 KEGG: ajs:Ajs_0196 DNA-damage-inducible protein D YP_003006514.1 PFAM: type III restriction protein res subunit; protein of unknown function DUF450; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; KEGG: neu:NE2499 DEAD/DEAH box helicase YP_003006515.1 TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: plu:plu4900 HipA protein YP_003006516.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sbn:Sbal195_0378 helix-turn-helix domain-containing protein YP_003006517.1 PFAM: Resolvase domain; KEGG: spc:Sputcn32_3979 resolvase domain-containing protein YP_003006518.1 KEGG: shm:Shewmr7_0345 hypothetical protein YP_003006520.1 PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; KEGG: tbd:Tbd_2685 DEAD/DEAH box helicase YP_003006521.1 PFAM: FRG domain protein; KEGG: gbm:Gbem_3768 FRG domain protein YP_003006522.1 PFAM: restriction modification system DNA specificity domain; KEGG: ccs:CCNA_00657 type I restriction-modification system specificity subunit YP_003006523.1 PFAM: N-6 DNA methylase; KEGG: mfa:Mfla_2604 N-6 DNA methylase YP_003006524.1 TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Prophage CP4-57 regulatory; KEGG: pmr:PMI3144 excisionase YP_003006525.1 TIGRFAM: DNA binding domain protein, excisionase family; KEGG: spc:Sputcn32_3991 phage transcriptional regulator, AlpA YP_003006526.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_003006527.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_003006528.1 KEGG: net:Neut_2254 putative DNA helicase YP_003006529.1 PFAM: replication C family protein; KEGG: sty:HCM1.221 putative replication protein YP_003006531.1 PFAM: integrase family protein; KEGG: spc:Sputcn32_4000 phage integrase family protein YP_003006532.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_003006533.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_003006534.1 PFAM: protein of unknown function DUF37; KEGG: sgl:SG2430 hypothetical protein YP_003006535.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_003006536.1 in Escherichia coli transcription of this gene is enhanced by polyamines