-- dump date   	20140619_070704
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
399742000001	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
399742000002	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
399742000003	Autotransporter beta-domain; Region: Autotransporter; pfam03797
399742000004	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
399742000005	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742000006	dimer interface [polypeptide binding]; other site
399742000007	phosphorylation site [posttranslational modification]
399742000008	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742000009	ATP binding site [chemical binding]; other site
399742000010	G-X-G motif; other site
399742000011	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
399742000012	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742000013	active site
399742000014	phosphorylation site [posttranslational modification]
399742000015	intermolecular recognition site; other site
399742000016	dimerization interface [polypeptide binding]; other site
399742000017	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742000018	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742000019	active site
399742000020	phosphorylation site [posttranslational modification]
399742000021	intermolecular recognition site; other site
399742000022	dimerization interface [polypeptide binding]; other site
399742000023	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742000024	DNA binding residues [nucleotide binding]
399742000025	dimerization interface [polypeptide binding]; other site
399742000026	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
399742000027	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
399742000028	Autotransporter beta-domain; Region: Autotransporter; pfam03797
399742000029	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
399742000030	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
399742000031	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742000032	putative DNA binding site [nucleotide binding]; other site
399742000033	Thioredoxin (TRX) superfamily; a large, diverse group of proteins containing a TRX-fold. Many members contain a classic TRX domain with a redox active CXXC motif. They function as protein disulfide oxidoreductases (PDOs), altering the redox state of...; Region: TRX_superfamily; cd01659
399742000034	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
399742000035	dimer interface [polypeptide binding]; other site
399742000036	pyridoxal binding site [chemical binding]; other site
399742000037	ATP binding site [chemical binding]; other site
399742000038	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
399742000039	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
399742000040	catalytic residue [active]
399742000041	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
399742000042	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742000043	DNA-binding site [nucleotide binding]; DNA binding site
399742000044	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742000045	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742000046	homodimer interface [polypeptide binding]; other site
399742000047	catalytic residue [active]
399742000048	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
399742000049	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
399742000050	catalytic triad [active]
399742000051	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
399742000052	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
399742000053	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
399742000054	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
399742000055	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
399742000056	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
399742000057	active site
399742000058	FMN binding site [chemical binding]; other site
399742000059	substrate binding site [chemical binding]; other site
399742000060	homotetramer interface [polypeptide binding]; other site
399742000061	catalytic residue [active]
399742000062	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742000063	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742000064	active site
399742000065	catalytic tetrad [active]
399742000066	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
399742000067	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742000068	NAD(P) binding site [chemical binding]; other site
399742000069	active site
399742000070	multiple promoter invertase; Provisional; Region: mpi; PRK13413
399742000071	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
399742000072	catalytic residues [active]
399742000073	catalytic nucleophile [active]
399742000074	Presynaptic Site I dimer interface [polypeptide binding]; other site
399742000075	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
399742000076	Synaptic Flat tetramer interface [polypeptide binding]; other site
399742000077	Synaptic Site I dimer interface [polypeptide binding]; other site
399742000078	DNA binding site [nucleotide binding]
399742000079	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
399742000080	DNA-binding interface [nucleotide binding]; DNA binding site
399742000081	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
399742000082	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
399742000083	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742000084	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742000085	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
399742000086	putative effector binding pocket; other site
399742000087	putative dimerization interface [polypeptide binding]; other site
399742000088	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
399742000089	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
399742000090	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
399742000091	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
399742000092	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
399742000093	active site
399742000094	DNA binding site [nucleotide binding]
399742000095	Int/Topo IB signature motif; other site
399742000096	AAA domain; Region: AAA_13; pfam13166
399742000097	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
399742000098	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
399742000099	FtsX-like permease family; Region: FtsX; pfam02687
399742000100	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
399742000101	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742000102	Walker A/P-loop; other site
399742000103	ATP binding site [chemical binding]; other site
399742000104	Q-loop/lid; other site
399742000105	ABC transporter signature motif; other site
399742000106	Walker B; other site
399742000107	D-loop; other site
399742000108	H-loop/switch region; other site
399742000109	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
399742000110	metal ion-dependent adhesion site (MIDAS); other site
399742000111	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
399742000112	Putative bacterial virulence factor; Region: Virul_Fac; pfam10139
399742000113	Virulence factor SrfB; Region: SrfB; pfam07520
399742000114	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
399742000115	metal ion-dependent adhesion site (MIDAS); other site
399742000116	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
399742000117	Coenzyme A binding pocket [chemical binding]; other site
399742000118	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
399742000119	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742000120	Ligand Binding Site [chemical binding]; other site
399742000121	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
399742000122	Putative glucoamylase; Region: Glycoamylase; pfam10091
399742000123	Second GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_2_like; cd11753
399742000124	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
399742000125	First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756
399742000126	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
399742000127	dimerization interface [polypeptide binding]; other site
399742000128	metal binding site [ion binding]; metal-binding site
399742000129	GnsA/GnsB family; Region: GnsAB; pfam08178
399742000130	plasmid-partitioning protein SopA; Provisional; Region: PRK13705
399742000131	MerR family regulatory protein; Region: MerR; pfam00376
399742000132	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
399742000133	P-loop; other site
399742000134	Magnesium ion binding site [ion binding]; other site
399742000135	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
399742000136	Magnesium ion binding site [ion binding]; other site
399742000137	plasmid-partitioning protein; Provisional; Region: PRK13698
399742000138	ParB-like nuclease domain; Region: ParB; smart00470
399742000139	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
399742000140	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742000141	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742000142	dimerization interface [polypeptide binding]; other site
399742000143	putative DNA binding site [nucleotide binding]; other site
399742000144	putative Zn2+ binding site [ion binding]; other site
399742000145	arsenical pump membrane protein; Provisional; Region: PRK15445
399742000146	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
399742000147	transmembrane helices; other site
399742000148	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
399742000149	ArsC family; Region: ArsC; pfam03960
399742000150	catalytic residues [active]
399742000151	small toxic polypeptide; Provisional; Region: PRK09738
399742000152	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
399742000153	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg6; cd04781
399742000154	DNA binding residues [nucleotide binding]
399742000155	putative dimer interface [polypeptide binding]; other site
399742000156	putative metal binding residues [ion binding]; other site
399742000157	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000158	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742000159	putative substrate translocation pore; other site
399742000160	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
399742000161	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
399742000162	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
399742000163	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742000164	binding surface
399742000165	TPR motif; other site
399742000166	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742000167	binding surface
399742000168	TPR motif; other site
399742000169	TPR repeat; Region: TPR_11; pfam13414
399742000170	TPR repeat; Region: TPR_11; pfam13414
399742000171	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742000172	binding surface
399742000173	TPR motif; other site
399742000174	TPR repeat; Region: TPR_11; pfam13414
399742000175	TPR repeat; Region: TPR_11; pfam13414
399742000176	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742000177	TPR motif; other site
399742000178	binding surface
399742000179	Sulfotransferase family; Region: Sulfotransfer_3; pfam13469
399742000180	Tetratricopeptide repeat; Region: TPR_16; pfam13432
399742000181	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
399742000182	Autotransporter beta-domain; Region: Autotransporter; pfam03797
399742000183	RelB antitoxin; Region: RelB; cl01171
399742000184	small toxic polypeptide; Provisional; Region: PRK09738
399742000185	ParB-like nuclease domain; Region: ParBc; cl02129
399742000186	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
399742000187	Plasmid SOS inhibition protein (PsiB); Region: PsiB; pfam06290
399742000188	PsiA protein; Region: PsiA; pfam06952
399742000189	Domain of unknown function (DUF932); Region: DUF932; pfam06067
399742000190	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
399742000191	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742000192	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742000193	catalytic residue [active]
399742000194	TraM protein; Region: Tra_M; cl11621
399742000195	TraA; Region: TraA; cl11503
399742000196	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
399742000197	TraE protein; Region: TraE; pfam05309
399742000198	conjugal transfer protein TraK; Provisional; Region: PRK13736
399742000199	TraK protein; Region: TraK; pfam06586
399742000200	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
399742000201	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
399742000202	conjugal transfer protein TraV; Provisional; Region: PRK13733
399742000203	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
399742000204	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
399742000205	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
399742000206	Type-F conjugative transfer system protein (TrbI_Ftype); Region: TrbI_Ftype; pfam09677
399742000207	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
399742000208	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
399742000209	Type-F conjugative transfer system pilin assembly protein; Region: TrbC_Ftype; cl09883
399742000210	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
399742000211	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
399742000212	F plasmid transfer operon protein; Region: TraF; pfam13728
399742000213	conjugal transfer protein TrbB; Provisional; Region: PRK13728
399742000214	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
399742000215	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
399742000216	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
399742000217	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
399742000218	type IV conjugative transfer system coupling protein TraD; Region: TraD_Ftype; TIGR02759
399742000219	F sex factor protein N terminal; Region: TraD_N; pfam12615
399742000220	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
399742000221	Walker A motif; other site
399742000222	ATP binding site [chemical binding]; other site
399742000223	Walker B motif; other site
399742000224	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
399742000225	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
399742000226	AAA domain; Region: AAA_30; pfam13604
399742000227	DNA helicase TraI; Region: TraI; pfam07057
399742000228	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
399742000229	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
399742000230	IncFII RepA protein family; Region: IncFII_repA; cl11495
399742000231	conjugal transfer protein TrbP; Provisional; Region: PRK13882
399742000232	TraX protein; Region: TraX; pfam05857
399742000233	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
399742000234	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
399742000235	YadA-like C-terminal region; Region: YadA; pfam03895
399742000236	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
399742000237	putative transposase OrfB; Reviewed; Region: PHA02517
399742000238	HTH-like domain; Region: HTH_21; pfam13276
399742000239	Integrase core domain; Region: rve; pfam00665
399742000240	Integrase core domain; Region: rve_3; pfam13683
399742000241	Transposase; Region: HTH_Tnp_1; pfam01527
399742000242	ParA-like protein; Provisional; Region: PHA02518
399742000243	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
399742000244	P-loop; other site
399742000245	Magnesium ion binding site [ion binding]; other site
399742000246	Phage integrase family; Region: Phage_integrase; pfam00589
399742000247	active site
399742000248	DNA binding site [nucleotide binding]
399742000249	Int/Topo IB signature motif; other site
399742000250	DnaA N-terminal domain; Region: DnaA_N; pfam11638
399742000251	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
399742000252	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742000253	Walker A motif; other site
399742000254	ATP binding site [chemical binding]; other site
399742000255	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
399742000256	Walker B motif; other site
399742000257	arginine finger; other site
399742000258	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
399742000259	DnaA box-binding interface [nucleotide binding]; other site
399742000260	DNA polymerase III subunit beta; Validated; Region: PRK05643
399742000261	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
399742000262	putative DNA binding surface [nucleotide binding]; other site
399742000263	dimer interface [polypeptide binding]; other site
399742000264	beta-clamp/clamp loader binding surface; other site
399742000265	beta-clamp/translesion DNA polymerase binding surface; other site
399742000266	recF protein; Region: recf; TIGR00611
399742000267	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742000268	Walker A/P-loop; other site
399742000269	ATP binding site [chemical binding]; other site
399742000270	Q-loop/lid; other site
399742000271	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742000272	ABC transporter signature motif; other site
399742000273	Walker B; other site
399742000274	D-loop; other site
399742000275	H-loop/switch region; other site
399742000276	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
399742000277	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742000278	Mg2+ binding site [ion binding]; other site
399742000279	G-X-G motif; other site
399742000280	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
399742000281	anchoring element; other site
399742000282	dimer interface [polypeptide binding]; other site
399742000283	ATP binding site [chemical binding]; other site
399742000284	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
399742000285	active site
399742000286	putative metal-binding site [ion binding]; other site
399742000287	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
399742000288	sugar phosphate phosphatase; Provisional; Region: PRK10513
399742000289	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742000290	active site
399742000291	motif I; other site
399742000292	motif II; other site
399742000293	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742000294	Transcriptional regulators [Transcription]; Region: FadR; COG2186
399742000295	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742000296	DNA-binding site [nucleotide binding]; DNA binding site
399742000297	FCD domain; Region: FCD; pfam07729
399742000298	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
399742000299	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
399742000300	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
399742000301	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
399742000302	active site
399742000303	intersubunit interface [polypeptide binding]; other site
399742000304	catalytic residue [active]
399742000305	galactonate dehydratase; Provisional; Region: PRK14017
399742000306	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
399742000307	putative active site pocket [active]
399742000308	putative metal binding site [ion binding]; other site
399742000309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000310	D-galactonate transporter; Region: 2A0114; TIGR00893
399742000311	putative substrate translocation pore; other site
399742000312	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000313	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
399742000314	hypothetical protein; Provisional; Region: PRK11616
399742000315	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
399742000316	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
399742000317	putative dimer interface [polypeptide binding]; other site
399742000318	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
399742000319	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
399742000320	putative dimer interface [polypeptide binding]; other site
399742000321	putative transporter; Validated; Region: PRK03818
399742000322	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
399742000323	TrkA-C domain; Region: TrkA_C; pfam02080
399742000324	TrkA-C domain; Region: TrkA_C; pfam02080
399742000325	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
399742000326	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
399742000327	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742000328	DNA-binding site [nucleotide binding]; DNA binding site
399742000329	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
399742000330	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
399742000331	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
399742000332	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742000333	active site turn [active]
399742000334	phosphorylation site [posttranslational modification]
399742000335	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
399742000336	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
399742000337	NAD binding site [chemical binding]; other site
399742000338	sugar binding site [chemical binding]; other site
399742000339	divalent metal binding site [ion binding]; other site
399742000340	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742000341	dimer interface [polypeptide binding]; other site
399742000342	Predicted membrane protein [Function unknown]; Region: COG2149
399742000343	Domain of unknown function (DUF202); Region: DUF202; pfam02656
399742000344	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
399742000345	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
399742000346	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
399742000347	catalytic residue [active]
399742000348	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
399742000349	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
399742000350	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000351	putative substrate translocation pore; other site
399742000352	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
399742000353	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742000354	Coenzyme A binding pocket [chemical binding]; other site
399742000355	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
399742000356	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
399742000357	PYR/PP interface [polypeptide binding]; other site
399742000358	dimer interface [polypeptide binding]; other site
399742000359	TPP binding site [chemical binding]; other site
399742000360	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
399742000361	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
399742000362	TPP-binding site [chemical binding]; other site
399742000363	dimer interface [polypeptide binding]; other site
399742000364	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
399742000365	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
399742000366	putative valine binding site [chemical binding]; other site
399742000367	dimer interface [polypeptide binding]; other site
399742000368	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
399742000369	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742000370	active site
399742000371	phosphorylation site [posttranslational modification]
399742000372	intermolecular recognition site; other site
399742000373	dimerization interface [polypeptide binding]; other site
399742000374	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742000375	DNA binding residues [nucleotide binding]
399742000376	dimerization interface [polypeptide binding]; other site
399742000377	sensory histidine kinase UhpB; Provisional; Region: PRK11644
399742000378	MASE1; Region: MASE1; pfam05231
399742000379	Histidine kinase; Region: HisKA_3; pfam07730
399742000380	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742000381	ATP binding site [chemical binding]; other site
399742000382	Mg2+ binding site [ion binding]; other site
399742000383	G-X-G motif; other site
399742000384	regulatory protein UhpC; Provisional; Region: PRK11663
399742000385	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000386	putative substrate translocation pore; other site
399742000387	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000388	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
399742000389	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000390	putative substrate translocation pore; other site
399742000391	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
399742000392	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
399742000393	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000394	putative substrate translocation pore; other site
399742000395	EamA-like transporter family; Region: EamA; pfam00892
399742000396	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
399742000397	EamA-like transporter family; Region: EamA; pfam00892
399742000398	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
399742000399	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
399742000400	methionine cluster; other site
399742000401	active site
399742000402	phosphorylation site [posttranslational modification]
399742000403	metal binding site [ion binding]; metal-binding site
399742000404	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
399742000405	beta-galactosidase; Region: BGL; TIGR03356
399742000406	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
399742000407	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
399742000408	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
399742000409	active site
399742000410	P-loop; other site
399742000411	phosphorylation site [posttranslational modification]
399742000412	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742000413	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742000414	DNA binding site [nucleotide binding]
399742000415	domain linker motif; other site
399742000416	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
399742000417	ligand binding site [chemical binding]; other site
399742000418	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742000419	Coenzyme A binding pocket [chemical binding]; other site
399742000420	pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613
399742000421	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742000422	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
399742000423	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000424	putative substrate translocation pore; other site
399742000425	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000426	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
399742000427	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
399742000428	tetramer interface [polypeptide binding]; other site
399742000429	active site
399742000430	Mg2+/Mn2+ binding site [ion binding]; other site
399742000431	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
399742000432	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
399742000433	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
399742000434	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
399742000435	DNA binding site [nucleotide binding]
399742000436	active site
399742000437	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
399742000438	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
399742000439	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
399742000440	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
399742000441	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742000442	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742000443	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000444	putative substrate translocation pore; other site
399742000445	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742000446	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742000447	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
399742000448	putative effector binding pocket; other site
399742000449	putative dimerization interface [polypeptide binding]; other site
399742000450	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
399742000451	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
399742000452	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
399742000453	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
399742000454	conserved cys residue [active]
399742000455	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742000456	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
399742000457	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
399742000458	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
399742000459	haemagglutination activity domain; Region: Haemagg_act; pfam05860
399742000460	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
399742000461	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
399742000462	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
399742000463	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
399742000464	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
399742000465	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
399742000466	Integrase core domain; Region: rve; pfam00665
399742000467	DDE domain; Region: DDE_Tnp_IS240; pfam13610
399742000468	Integrase core domain; Region: rve_2; pfam13333
399742000469	Protein of unknown function (DUF523); Region: DUF523; pfam04463
399742000470	Uncharacterized conserved protein [Function unknown]; Region: COG3272
399742000471	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
399742000472	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
399742000473	active site
399742000474	homotetramer interface [polypeptide binding]; other site
399742000475	transcriptional regulator MirA; Provisional; Region: PRK15043
399742000476	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
399742000477	DNA binding residues [nucleotide binding]
399742000478	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
399742000479	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
399742000480	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
399742000481	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
399742000482	HicB family; Region: HicB; pfam05534
399742000483	MgtE intracellular N domain; Region: MgtE_N; cl15244
399742000484	putative transporter; Provisional; Region: PRK11462
399742000485	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
399742000486	putative alpha-glucosidase; Provisional; Region: PRK10658
399742000487	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
399742000488	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
399742000489	active site
399742000490	homotrimer interface [polypeptide binding]; other site
399742000491	catalytic site [active]
399742000492	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
399742000493	AsmA family; Region: AsmA; pfam05170
399742000494	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
399742000495	Fimbrial protein; Region: Fimbrial; pfam00419
399742000496	Fimbrial protein; Region: Fimbrial; pfam00419
399742000497	Fimbrial protein; Region: Fimbrial; pfam00419
399742000498	Fimbrial protein; Region: Fimbrial; pfam00419
399742000499	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742000500	Fimbrial protein; Region: Fimbrial; cl01416
399742000501	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742000502	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742000503	Fimbrial protein; Region: Fimbrial; pfam00419
399742000504	Fimbrial protein; Region: Fimbrial; pfam00419
399742000505	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
399742000506	PapC N-terminal domain; Region: PapC_N; pfam13954
399742000507	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
399742000508	PapC C-terminal domain; Region: PapC_C; pfam13953
399742000509	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
399742000510	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
399742000511	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
399742000512	Fimbrial protein; Region: Fimbrial; pfam00419
399742000513	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
399742000514	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
399742000515	generic binding surface II; other site
399742000516	ssDNA binding site; other site
399742000517	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742000518	ATP binding site [chemical binding]; other site
399742000519	putative Mg++ binding site [ion binding]; other site
399742000520	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742000521	nucleotide binding region [chemical binding]; other site
399742000522	ATP-binding site [chemical binding]; other site
399742000523	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
399742000524	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
399742000525	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
399742000526	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
399742000527	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742000528	Zn2+ binding site [ion binding]; other site
399742000529	Mg2+ binding site [ion binding]; other site
399742000530	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
399742000531	synthetase active site [active]
399742000532	NTP binding site [chemical binding]; other site
399742000533	metal binding site [ion binding]; metal-binding site
399742000534	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
399742000535	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
399742000536	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
399742000537	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
399742000538	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
399742000539	catalytic site [active]
399742000540	G-X2-G-X-G-K; other site
399742000541	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
399742000542	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
399742000543	nucleotide binding pocket [chemical binding]; other site
399742000544	K-X-D-G motif; other site
399742000545	catalytic site [active]
399742000546	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
399742000547	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
399742000548	Sulfatase; Region: Sulfatase; pfam00884
399742000549	Predicted membrane protein [Function unknown]; Region: COG2860
399742000550	UPF0126 domain; Region: UPF0126; pfam03458
399742000551	UPF0126 domain; Region: UPF0126; pfam03458
399742000552	hypothetical protein; Provisional; Region: PRK11820
399742000553	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
399742000554	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
399742000555	ribonuclease PH; Reviewed; Region: rph; PRK00173
399742000556	Ribonuclease PH; Region: RNase_PH_bact; cd11362
399742000557	hexamer interface [polypeptide binding]; other site
399742000558	active site
399742000559	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742000560	active site
399742000561	division inhibitor protein; Provisional; Region: slmA; PRK09480
399742000562	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742000563	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
399742000564	trimer interface [polypeptide binding]; other site
399742000565	active site
399742000566	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
399742000567	Flavoprotein; Region: Flavoprotein; pfam02441
399742000568	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
399742000569	hypothetical protein; Reviewed; Region: PRK00024
399742000570	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
399742000571	MPN+ (JAMM) motif; other site
399742000572	Zinc-binding site [ion binding]; other site
399742000573	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
399742000574	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
399742000575	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
399742000576	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
399742000577	DNA binding site [nucleotide binding]
399742000578	catalytic residue [active]
399742000579	H2TH interface [polypeptide binding]; other site
399742000580	putative catalytic residues [active]
399742000581	turnover-facilitating residue; other site
399742000582	intercalation triad [nucleotide binding]; other site
399742000583	8OG recognition residue [nucleotide binding]; other site
399742000584	putative reading head residues; other site
399742000585	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
399742000586	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
399742000587	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
399742000588	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
399742000589	active site
399742000590	(T/H)XGH motif; other site
399742000591	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
399742000592	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
399742000593	putative metal binding site; other site
399742000594	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
399742000595	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
399742000596	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
399742000597	Sulfatase; Region: Sulfatase; cl17466
399742000598	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
399742000599	putative glycosyl transferase; Provisional; Region: PRK10073
399742000600	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
399742000601	active site
399742000602	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
399742000603	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
399742000604	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
399742000605	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
399742000606	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
399742000607	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
399742000608	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
399742000609	putative active site [active]
399742000610	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
399742000611	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
399742000612	putative active site [active]
399742000613	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
399742000614	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
399742000615	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
399742000616	putative active site [active]
399742000617	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
399742000618	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
399742000619	NADP binding site [chemical binding]; other site
399742000620	homopentamer interface [polypeptide binding]; other site
399742000621	substrate binding site [chemical binding]; other site
399742000622	active site
399742000623	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
399742000624	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
399742000625	substrate-cofactor binding pocket; other site
399742000626	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742000627	catalytic residue [active]
399742000628	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
399742000629	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
399742000630	NAD(P) binding site [chemical binding]; other site
399742000631	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
399742000632	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
399742000633	putative metal binding site; other site
399742000634	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
399742000635	NodB motif; other site
399742000636	putative active site [active]
399742000637	putative catalytic site [active]
399742000638	Zn binding site [ion binding]; other site
399742000639	AmiB activator; Provisional; Region: PRK11637
399742000640	Peptidase family M23; Region: Peptidase_M23; pfam01551
399742000641	phosphoglyceromutase; Provisional; Region: PRK05434
399742000642	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
399742000643	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
399742000644	active site residue [active]
399742000645	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
399742000646	GSH binding site [chemical binding]; other site
399742000647	catalytic residues [active]
399742000648	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
399742000649	SecA binding site; other site
399742000650	Preprotein binding site; other site
399742000651	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
399742000652	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
399742000653	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
399742000654	serine acetyltransferase; Provisional; Region: cysE; PRK11132
399742000655	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
399742000656	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
399742000657	trimer interface [polypeptide binding]; other site
399742000658	active site
399742000659	substrate binding site [chemical binding]; other site
399742000660	CoA binding site [chemical binding]; other site
399742000661	putative rRNA methylase; Provisional; Region: PRK10358
399742000662	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
399742000663	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
399742000664	active site
399742000665	substrate binding site [chemical binding]; other site
399742000666	FMN binding site [chemical binding]; other site
399742000667	putative catalytic residues [active]
399742000668	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
399742000669	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742000670	DNA-binding site [nucleotide binding]; DNA binding site
399742000671	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
399742000672	L-lactate permease; Provisional; Region: PRK10420
399742000673	glycolate transporter; Provisional; Region: PRK09695
399742000674	hypothetical protein; Provisional; Region: PRK11020
399742000675	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
399742000676	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
399742000677	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
399742000678	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
399742000679	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
399742000680	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
399742000681	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
399742000682	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
399742000683	active site
399742000684	P-loop; other site
399742000685	phosphorylation site [posttranslational modification]
399742000686	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
399742000687	active site
399742000688	phosphorylation site [posttranslational modification]
399742000689	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
399742000690	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
399742000691	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742000692	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742000693	putative glutathione S-transferase; Provisional; Region: PRK10357
399742000694	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
399742000695	putative C-terminal domain interface [polypeptide binding]; other site
399742000696	putative GSH binding site (G-site) [chemical binding]; other site
399742000697	putative dimer interface [polypeptide binding]; other site
399742000698	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
399742000699	dimer interface [polypeptide binding]; other site
399742000700	N-terminal domain interface [polypeptide binding]; other site
399742000701	putative substrate binding pocket (H-site) [chemical binding]; other site
399742000702	selenocysteine synthase; Provisional; Region: PRK04311
399742000703	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
399742000704	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
399742000705	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
399742000706	catalytic residue [active]
399742000707	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
399742000708	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
399742000709	G1 box; other site
399742000710	putative GEF interaction site [polypeptide binding]; other site
399742000711	GTP/Mg2+ binding site [chemical binding]; other site
399742000712	Switch I region; other site
399742000713	G2 box; other site
399742000714	G3 box; other site
399742000715	Switch II region; other site
399742000716	G4 box; other site
399742000717	G5 box; other site
399742000718	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
399742000719	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
399742000720	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
399742000721	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
399742000722	putative alcohol dehydrogenase; Provisional; Region: PRK09860
399742000723	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
399742000724	dimer interface [polypeptide binding]; other site
399742000725	active site
399742000726	metal binding site [ion binding]; metal-binding site
399742000727	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
399742000728	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
399742000729	NAD(P) binding site [chemical binding]; other site
399742000730	catalytic residues [active]
399742000731	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742000732	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742000733	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742000734	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
399742000735	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
399742000736	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
399742000737	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
399742000738	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
399742000739	Autotransporter beta-domain; Region: Autotransporter; cl17461
399742000740	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
399742000741	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742000742	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742000743	homodimer interface [polypeptide binding]; other site
399742000744	catalytic residue [active]
399742000745	alpha-amylase; Reviewed; Region: malS; PRK09505
399742000746	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
399742000747	active site
399742000748	catalytic site [active]
399742000749	hypothetical protein; Provisional; Region: PRK10356
399742000750	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
399742000751	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
399742000752	putative dimerization interface [polypeptide binding]; other site
399742000753	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
399742000754	putative ligand binding site [chemical binding]; other site
399742000755	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742000756	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742000757	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742000758	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742000759	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742000760	TM-ABC transporter signature motif; other site
399742000761	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
399742000762	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742000763	Walker A/P-loop; other site
399742000764	ATP binding site [chemical binding]; other site
399742000765	Q-loop/lid; other site
399742000766	ABC transporter signature motif; other site
399742000767	Walker B; other site
399742000768	D-loop; other site
399742000769	H-loop/switch region; other site
399742000770	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742000771	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
399742000772	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
399742000773	putative ligand binding site [chemical binding]; other site
399742000774	xylose isomerase; Provisional; Region: PRK05474
399742000775	xylose isomerase; Region: xylose_isom_A; TIGR02630
399742000776	xylulokinase; Provisional; Region: PRK15027
399742000777	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
399742000778	N- and C-terminal domain interface [polypeptide binding]; other site
399742000779	active site
399742000780	MgATP binding site [chemical binding]; other site
399742000781	catalytic site [active]
399742000782	metal binding site [ion binding]; metal-binding site
399742000783	xylulose binding site [chemical binding]; other site
399742000784	homodimer interface [polypeptide binding]; other site
399742000785	Isochorismatase family; Region: Isochorismatase; pfam00857
399742000786	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
399742000787	catalytic triad [active]
399742000788	conserved cis-peptide bond; other site
399742000789	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
399742000790	conserved cys residue [active]
399742000791	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742000792	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
399742000793	Acyltransferase family; Region: Acyl_transf_3; pfam01757
399742000794	YsaB-like lipoprotein; Region: YsaB; pfam13983
399742000795	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
399742000796	dimer interface [polypeptide binding]; other site
399742000797	motif 1; other site
399742000798	active site
399742000799	motif 2; other site
399742000800	motif 3; other site
399742000801	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
399742000802	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
399742000803	Predicted transcriptional regulator [Transcription]; Region: COG2944
399742000804	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742000805	salt bridge; other site
399742000806	non-specific DNA binding site [nucleotide binding]; other site
399742000807	sequence-specific DNA binding site [nucleotide binding]; other site
399742000808	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
399742000809	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742000810	DNA-binding site [nucleotide binding]; DNA binding site
399742000811	RNA-binding motif; other site
399742000812	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
399742000813	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
399742000814	dimerization interface [polypeptide binding]; other site
399742000815	ligand binding site [chemical binding]; other site
399742000816	NADP binding site [chemical binding]; other site
399742000817	catalytic site [active]
399742000818	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000819	D-galactonate transporter; Region: 2A0114; TIGR00893
399742000820	putative substrate translocation pore; other site
399742000821	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
399742000822	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
399742000823	substrate binding site [chemical binding]; other site
399742000824	ATP binding site [chemical binding]; other site
399742000825	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
399742000826	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742000827	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742000828	DNA binding site [nucleotide binding]
399742000829	domain linker motif; other site
399742000830	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
399742000831	putative dimerization interface [polypeptide binding]; other site
399742000832	putative ligand binding site [chemical binding]; other site
399742000833	putative outer membrane lipoprotein; Provisional; Region: PRK10510
399742000834	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
399742000835	ligand binding site [chemical binding]; other site
399742000836	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
399742000837	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
399742000838	molybdopterin cofactor binding site [chemical binding]; other site
399742000839	substrate binding site [chemical binding]; other site
399742000840	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
399742000841	molybdopterin cofactor binding site; other site
399742000842	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
399742000843	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742000844	Coenzyme A binding pocket [chemical binding]; other site
399742000845	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
399742000846	Autotransporter beta-domain; Region: Autotransporter; cl17461
399742000847	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
399742000848	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742000849	putative substrate translocation pore; other site
399742000850	phosphoethanolamine transferase; Provisional; Region: PRK11560
399742000851	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
399742000852	Sulfatase; Region: Sulfatase; pfam00884
399742000853	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
399742000854	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
399742000855	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
399742000856	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
399742000857	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
399742000858	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
399742000859	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742000860	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742000861	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
399742000862	peptide binding site [polypeptide binding]; other site
399742000863	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
399742000864	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742000865	dimer interface [polypeptide binding]; other site
399742000866	conserved gate region; other site
399742000867	putative PBP binding loops; other site
399742000868	ABC-ATPase subunit interface; other site
399742000869	dipeptide transporter; Provisional; Region: PRK10913
399742000870	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
399742000871	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742000872	dimer interface [polypeptide binding]; other site
399742000873	conserved gate region; other site
399742000874	putative PBP binding loops; other site
399742000875	ABC-ATPase subunit interface; other site
399742000876	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
399742000877	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742000878	Walker A/P-loop; other site
399742000879	ATP binding site [chemical binding]; other site
399742000880	Q-loop/lid; other site
399742000881	ABC transporter signature motif; other site
399742000882	Walker B; other site
399742000883	D-loop; other site
399742000884	H-loop/switch region; other site
399742000885	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
399742000886	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
399742000887	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742000888	Walker A/P-loop; other site
399742000889	ATP binding site [chemical binding]; other site
399742000890	Q-loop/lid; other site
399742000891	ABC transporter signature motif; other site
399742000892	Walker B; other site
399742000893	D-loop; other site
399742000894	H-loop/switch region; other site
399742000895	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
399742000896	pantothenate kinase; Provisional; Region: PRK05439
399742000897	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
399742000898	ATP-binding site [chemical binding]; other site
399742000899	CoA-binding site [chemical binding]; other site
399742000900	Mg2+-binding site [ion binding]; other site
399742000901	elongation factor Tu; Reviewed; Region: PRK00049
399742000902	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
399742000903	G1 box; other site
399742000904	GEF interaction site [polypeptide binding]; other site
399742000905	GTP/Mg2+ binding site [chemical binding]; other site
399742000906	Switch I region; other site
399742000907	G2 box; other site
399742000908	G3 box; other site
399742000909	Switch II region; other site
399742000910	G4 box; other site
399742000911	G5 box; other site
399742000912	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
399742000913	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
399742000914	Antibiotic Binding Site [chemical binding]; other site
399742000915	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
399742000916	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
399742000917	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
399742000918	putative homodimer interface [polypeptide binding]; other site
399742000919	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
399742000920	heterodimer interface [polypeptide binding]; other site
399742000921	homodimer interface [polypeptide binding]; other site
399742000922	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
399742000923	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
399742000924	23S rRNA interface [nucleotide binding]; other site
399742000925	L7/L12 interface [polypeptide binding]; other site
399742000926	putative thiostrepton binding site; other site
399742000927	L25 interface [polypeptide binding]; other site
399742000928	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
399742000929	mRNA/rRNA interface [nucleotide binding]; other site
399742000930	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
399742000931	23S rRNA interface [nucleotide binding]; other site
399742000932	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
399742000933	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
399742000934	core dimer interface [polypeptide binding]; other site
399742000935	peripheral dimer interface [polypeptide binding]; other site
399742000936	L10 interface [polypeptide binding]; other site
399742000937	L11 interface [polypeptide binding]; other site
399742000938	putative EF-Tu interaction site [polypeptide binding]; other site
399742000939	putative EF-G interaction site [polypeptide binding]; other site
399742000940	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
399742000941	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
399742000942	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
399742000943	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
399742000944	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
399742000945	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
399742000946	RPB3 interaction site [polypeptide binding]; other site
399742000947	RPB1 interaction site [polypeptide binding]; other site
399742000948	RPB11 interaction site [polypeptide binding]; other site
399742000949	RPB10 interaction site [polypeptide binding]; other site
399742000950	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
399742000951	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
399742000952	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
399742000953	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
399742000954	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
399742000955	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
399742000956	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
399742000957	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
399742000958	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
399742000959	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
399742000960	DNA binding site [nucleotide binding]
399742000961	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
399742000962	methionine cluster; other site
399742000963	PTS system, Lactose/Cellobiose specific IIA subunit; Region: PTS_IIA; pfam02255
399742000964	active site
399742000965	phosphorylation site [posttranslational modification]
399742000966	metal binding site [ion binding]; metal-binding site
399742000967	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
399742000968	active site
399742000969	P-loop; other site
399742000970	phosphorylation site [posttranslational modification]
399742000971	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742000972	DNA-binding site [nucleotide binding]; DNA binding site
399742000973	RNA-binding motif; other site
399742000974	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
399742000975	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742000976	FeS/SAM binding site; other site
399742000977	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
399742000978	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
399742000979	ThiS interaction site; other site
399742000980	putative active site [active]
399742000981	tetramer interface [polypeptide binding]; other site
399742000982	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
399742000983	thiS-thiF/thiG interaction site; other site
399742000984	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
399742000985	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
399742000986	ATP binding site [chemical binding]; other site
399742000987	substrate interface [chemical binding]; other site
399742000988	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
399742000989	thiamine phosphate binding site [chemical binding]; other site
399742000990	active site
399742000991	pyrophosphate binding site [ion binding]; other site
399742000992	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
399742000993	ThiC-associated domain; Region: ThiC-associated; pfam13667
399742000994	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
399742000995	anti-RNA polymerase sigma 70 factor; Provisional; Region: PRK11718
399742000996	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
399742000997	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
399742000998	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
399742000999	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
399742001000	putative NADH binding site [chemical binding]; other site
399742001001	putative active site [active]
399742001002	nudix motif; other site
399742001003	putative metal binding site [ion binding]; other site
399742001004	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
399742001005	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
399742001006	substrate binding site [chemical binding]; other site
399742001007	active site
399742001008	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
399742001009	Active_site [active]
399742001010	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
399742001011	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
399742001012	IHF dimer interface [polypeptide binding]; other site
399742001013	IHF - DNA interface [nucleotide binding]; other site
399742001014	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
399742001015	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
399742001016	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
399742001017	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
399742001018	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
399742001019	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
399742001020	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
399742001021	purine monophosphate binding site [chemical binding]; other site
399742001022	dimer interface [polypeptide binding]; other site
399742001023	putative catalytic residues [active]
399742001024	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
399742001025	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
399742001026	homoserine O-succinyltransferase; Provisional; Region: PRK05368
399742001027	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
399742001028	proposed active site lysine [active]
399742001029	conserved cys residue [active]
399742001030	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
399742001031	malate synthase A; Region: malate_syn_A; TIGR01344
399742001032	active site
399742001033	isocitrate lyase; Provisional; Region: PRK15063
399742001034	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
399742001035	tetramer interface [polypeptide binding]; other site
399742001036	active site
399742001037	Mg2+/Mn2+ binding site [ion binding]; other site
399742001038	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
399742001039	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
399742001040	transcriptional repressor IclR; Provisional; Region: PRK11569
399742001041	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
399742001042	Bacterial transcriptional regulator; Region: IclR; pfam01614
399742001043	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
399742001044	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
399742001045	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
399742001046	substrate binding pocket [chemical binding]; other site
399742001047	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
399742001048	B12 binding site [chemical binding]; other site
399742001049	cobalt ligand [ion binding]; other site
399742001050	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
399742001051	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
399742001052	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
399742001053	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
399742001054	probable addiction module antidote protein; Region: dnstrm_HI1420; TIGR02684
399742001055	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
399742001056	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
399742001057	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742001058	RNA binding surface [nucleotide binding]; other site
399742001059	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
399742001060	probable active site [active]
399742001061	hypothetical protein; Provisional; Region: PRK10515
399742001062	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
399742001063	Sodium Bile acid symporter family; Region: SBF; cl17470
399742001064	aspartate kinase III; Validated; Region: PRK09084
399742001065	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
399742001066	nucleotide binding site [chemical binding]; other site
399742001067	substrate binding site [chemical binding]; other site
399742001068	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
399742001069	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
399742001070	dimer interface [polypeptide binding]; other site
399742001071	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
399742001072	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
399742001073	active site
399742001074	dimer interface [polypeptide binding]; other site
399742001075	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
399742001076	dimer interface [polypeptide binding]; other site
399742001077	active site
399742001078	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
399742001079	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
399742001080	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
399742001081	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
399742001082	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
399742001083	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
399742001084	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742001085	dimer interface [polypeptide binding]; other site
399742001086	conserved gate region; other site
399742001087	putative PBP binding loops; other site
399742001088	ABC-ATPase subunit interface; other site
399742001089	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742001090	dimer interface [polypeptide binding]; other site
399742001091	conserved gate region; other site
399742001092	putative PBP binding loops; other site
399742001093	ABC-ATPase subunit interface; other site
399742001094	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
399742001095	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
399742001096	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
399742001097	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
399742001098	Walker A/P-loop; other site
399742001099	ATP binding site [chemical binding]; other site
399742001100	Q-loop/lid; other site
399742001101	ABC transporter signature motif; other site
399742001102	Walker B; other site
399742001103	D-loop; other site
399742001104	H-loop/switch region; other site
399742001105	TOBE domain; Region: TOBE_2; pfam08402
399742001106	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
399742001107	trimer interface; other site
399742001108	sugar binding site [chemical binding]; other site
399742001109	maltose regulon periplasmic protein; Provisional; Region: PRK10564
399742001110	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
399742001111	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
399742001112	UbiA prenyltransferase family; Region: UbiA; pfam01040
399742001113	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
399742001114	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
399742001115	putative acyl-acceptor binding pocket; other site
399742001116	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
399742001117	LexA repressor; Validated; Region: PRK00215
399742001118	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
399742001119	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742001120	Catalytic site [active]
399742001121	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
399742001122	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
399742001123	hypothetical protein; Provisional; Region: PRK10428
399742001124	ferric uptake regulator; Provisional; Region: fur; PRK09462
399742001125	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
399742001126	metal binding site 2 [ion binding]; metal-binding site
399742001127	putative DNA binding helix; other site
399742001128	metal binding site 1 [ion binding]; metal-binding site
399742001129	dimer interface [polypeptide binding]; other site
399742001130	structural Zn2+ binding site [ion binding]; other site
399742001131	Cupin domain; Region: Cupin_2; cl17218
399742001132	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
399742001133	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
399742001134	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
399742001135	FMN binding site [chemical binding]; other site
399742001136	active site
399742001137	catalytic residues [active]
399742001138	substrate binding site [chemical binding]; other site
399742001139	phage shock protein G; Reviewed; Region: pspG; PRK09459
399742001140	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
399742001141	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
399742001142	NADP binding site [chemical binding]; other site
399742001143	dimer interface [polypeptide binding]; other site
399742001144	replicative DNA helicase; Provisional; Region: PRK08006
399742001145	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
399742001146	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
399742001147	Walker A motif; other site
399742001148	ATP binding site [chemical binding]; other site
399742001149	Walker B motif; other site
399742001150	DNA binding loops [nucleotide binding]
399742001151	alanine racemase; Reviewed; Region: alr; PRK00053
399742001152	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
399742001153	active site
399742001154	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
399742001155	substrate binding site [chemical binding]; other site
399742001156	catalytic residues [active]
399742001157	dimer interface [polypeptide binding]; other site
399742001158	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
399742001159	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742001160	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742001161	homodimer interface [polypeptide binding]; other site
399742001162	catalytic residue [active]
399742001163	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742001164	active site
399742001165	motif I; other site
399742001166	motif II; other site
399742001167	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
399742001168	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
399742001169	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
399742001170	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
399742001171	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
399742001172	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
399742001173	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
399742001174	dimer interface [polypeptide binding]; other site
399742001175	ssDNA binding site [nucleotide binding]; other site
399742001176	tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742001177	putative single-stranded DNA-binding protein; Region: PHA01740
399742001178	PAS domain S-box; Region: sensory_box; TIGR00229
399742001179	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742001180	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742001181	metal binding site [ion binding]; metal-binding site
399742001182	active site
399742001183	I-site; other site
399742001184	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
399742001185	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
399742001186	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742001187	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
399742001188	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742001189	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
399742001190	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
399742001191	DNA binding residues [nucleotide binding]
399742001192	dimer interface [polypeptide binding]; other site
399742001193	[2Fe-2S] cluster binding site [ion binding]; other site
399742001194	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
399742001195	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
399742001196	putative C-terminal domain interface [polypeptide binding]; other site
399742001197	putative GSH binding site (G-site) [chemical binding]; other site
399742001198	putative dimer interface [polypeptide binding]; other site
399742001199	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
399742001200	putative N-terminal domain interface [polypeptide binding]; other site
399742001201	putative dimer interface [polypeptide binding]; other site
399742001202	putative substrate binding pocket (H-site) [chemical binding]; other site
399742001203	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
399742001204	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
399742001205	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
399742001206	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742001207	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742001208	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
399742001209	putative dimerization interface [polypeptide binding]; other site
399742001210	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
399742001211	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
399742001212	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
399742001213	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
399742001214	Na binding site [ion binding]; other site
399742001215	Predicted membrane protein [Function unknown]; Region: COG3162
399742001216	acetyl-CoA synthetase; Provisional; Region: PRK00174
399742001217	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
399742001218	active site
399742001219	CoA binding site [chemical binding]; other site
399742001220	acyl-activating enzyme (AAE) consensus motif; other site
399742001221	AMP binding site [chemical binding]; other site
399742001222	acetate binding site [chemical binding]; other site
399742001223	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
399742001224	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
399742001225	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
399742001226	short chain dehydrogenase; Provisional; Region: PRK06523
399742001227	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742001228	NAD(P) binding site [chemical binding]; other site
399742001229	active site
399742001230	Predicted transcriptional regulators [Transcription]; Region: COG1733
399742001231	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
399742001232	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742001233	molybdopterin cofactor binding site; other site
399742001234	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
399742001235	molybdopterin cofactor binding site; other site
399742001236	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742001237	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
399742001238	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742001239	active site
399742001240	phosphorylation site [posttranslational modification]
399742001241	intermolecular recognition site; other site
399742001242	dimerization interface [polypeptide binding]; other site
399742001243	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742001244	DNA binding site [nucleotide binding]
399742001245	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
399742001246	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
399742001247	substrate binding site [chemical binding]; other site
399742001248	ATP binding site [chemical binding]; other site
399742001249	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
399742001250	intersubunit interface [polypeptide binding]; other site
399742001251	active site
399742001252	zinc binding site [ion binding]; other site
399742001253	Na+ binding site [ion binding]; other site
399742001254	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
399742001255	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
399742001256	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
399742001257	putative ligand binding site [chemical binding]; other site
399742001258	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742001259	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742001260	TM-ABC transporter signature motif; other site
399742001261	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
399742001262	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742001263	Walker A/P-loop; other site
399742001264	ATP binding site [chemical binding]; other site
399742001265	Q-loop/lid; other site
399742001266	ABC transporter signature motif; other site
399742001267	Walker B; other site
399742001268	D-loop; other site
399742001269	H-loop/switch region; other site
399742001270	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742001271	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742001272	dimerization interface [polypeptide binding]; other site
399742001273	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742001274	dimer interface [polypeptide binding]; other site
399742001275	phosphorylation site [posttranslational modification]
399742001276	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742001277	ATP binding site [chemical binding]; other site
399742001278	Mg2+ binding site [ion binding]; other site
399742001279	G-X-G motif; other site
399742001280	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742001281	active site
399742001282	phosphorylation site [posttranslational modification]
399742001283	intermolecular recognition site; other site
399742001284	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
399742001285	Coenzyme A binding pocket [chemical binding]; other site
399742001286	putative inner membrane protein; Provisional; Region: PRK09823
399742001287	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742001288	non-specific DNA binding site [nucleotide binding]; other site
399742001289	salt bridge; other site
399742001290	sequence-specific DNA binding site [nucleotide binding]; other site
399742001291	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
399742001292	putative hydrolase; Provisional; Region: PRK02113
399742001293	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
399742001294	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742001295	Coenzyme A binding pocket [chemical binding]; other site
399742001296	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
399742001297	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
399742001298	active site
399742001299	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
399742001300	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
399742001301	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
399742001302	active site
399742001303	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
399742001304	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
399742001305	Walker A/P-loop; other site
399742001306	ATP binding site [chemical binding]; other site
399742001307	Q-loop/lid; other site
399742001308	ABC transporter signature motif; other site
399742001309	Walker B; other site
399742001310	D-loop; other site
399742001311	H-loop/switch region; other site
399742001312	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
399742001313	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742001314	Walker A/P-loop; other site
399742001315	ATP binding site [chemical binding]; other site
399742001316	Q-loop/lid; other site
399742001317	ABC transporter signature motif; other site
399742001318	Walker B; other site
399742001319	D-loop; other site
399742001320	H-loop/switch region; other site
399742001321	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
399742001322	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
399742001323	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
399742001324	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
399742001325	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
399742001326	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
399742001327	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742001328	DNA-binding site [nucleotide binding]; DNA binding site
399742001329	UTRA domain; Region: UTRA; pfam07702
399742001330	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
399742001331	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742001332	dimer interface [polypeptide binding]; other site
399742001333	conserved gate region; other site
399742001334	putative PBP binding loops; other site
399742001335	ABC-ATPase subunit interface; other site
399742001336	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
399742001337	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
399742001338	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
399742001339	Walker A/P-loop; other site
399742001340	ATP binding site [chemical binding]; other site
399742001341	Q-loop/lid; other site
399742001342	ABC transporter signature motif; other site
399742001343	Walker B; other site
399742001344	D-loop; other site
399742001345	H-loop/switch region; other site
399742001346	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
399742001347	dimer interface [polypeptide binding]; other site
399742001348	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742001349	hypothetical protein; Provisional; Region: PRK10220
399742001350	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
399742001351	PhnA protein; Region: PhnA; pfam03831
399742001352	hypothetical protein; Provisional; Region: PRK09866
399742001353	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
399742001354	G1 box; other site
399742001355	GTP/Mg2+ binding site [chemical binding]; other site
399742001356	G2 box; other site
399742001357	Switch I region; other site
399742001358	G3 box; other site
399742001359	Switch II region; other site
399742001360	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
399742001361	G2 box; other site
399742001362	Switch I region; other site
399742001363	G3 box; other site
399742001364	Switch II region; other site
399742001365	G4 box; other site
399742001366	G5 box; other site
399742001367	YjcZ-like protein; Region: YjcZ; pfam13990
399742001368	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
399742001369	proline/glycine betaine transporter; Provisional; Region: PRK10642
399742001370	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742001371	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742001372	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
399742001373	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
399742001374	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
399742001375	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
399742001376	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
399742001377	Autotransporter beta-domain; Region: Autotransporter; pfam03797
399742001378	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
399742001379	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742001380	Helix-turn-helix domain; Region: HTH_18; pfam12833
399742001381	putative transcriptional regulator; Provisional; Region: PRK11640
399742001382	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742001383	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
399742001384	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
399742001385	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
399742001386	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
399742001387	DsbD alpha interface [polypeptide binding]; other site
399742001388	catalytic residues [active]
399742001389	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
399742001390	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
399742001391	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
399742001392	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
399742001393	Aspartase; Region: Aspartase; cd01357
399742001394	active sites [active]
399742001395	tetramer interface [polypeptide binding]; other site
399742001396	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
399742001397	putative transporter; Provisional; Region: PRK11021
399742001398	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
399742001399	oligomerisation interface [polypeptide binding]; other site
399742001400	mobile loop; other site
399742001401	roof hairpin; other site
399742001402	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
399742001403	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
399742001404	ring oligomerisation interface [polypeptide binding]; other site
399742001405	ATP/Mg binding site [chemical binding]; other site
399742001406	stacking interactions; other site
399742001407	hinge regions; other site
399742001408	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
399742001409	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
399742001410	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742001411	FeS/SAM binding site; other site
399742001412	elongation factor P; Validated; Region: PRK00529
399742001413	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
399742001414	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
399742001415	RNA binding site [nucleotide binding]; other site
399742001416	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
399742001417	RNA binding site [nucleotide binding]; other site
399742001418	Predicted small secreted protein [Function unknown]; Region: COG5510
399742001419	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
399742001420	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742001421	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742001422	DNA binding residues [nucleotide binding]
399742001423	dimerization interface [polypeptide binding]; other site
399742001424	multidrug efflux system protein; Provisional; Region: PRK11431
399742001425	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
399742001426	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
399742001427	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
399742001428	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
399742001429	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
399742001430	Iron-sulfur protein interface; other site
399742001431	proximal quinone binding site [chemical binding]; other site
399742001432	C-subunit interface; other site
399742001433	distal quinone binding site; other site
399742001434	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
399742001435	D-subunit interface [polypeptide binding]; other site
399742001436	Iron-sulfur protein interface; other site
399742001437	proximal quinone binding site [chemical binding]; other site
399742001438	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
399742001439	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
399742001440	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
399742001441	L-aspartate oxidase; Provisional; Region: PRK06175
399742001442	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
399742001443	poxB regulator PoxA; Provisional; Region: PRK09350
399742001444	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
399742001445	motif 1; other site
399742001446	dimer interface [polypeptide binding]; other site
399742001447	active site
399742001448	motif 2; other site
399742001449	motif 3; other site
399742001450	putative mechanosensitive channel protein; Provisional; Region: PRK10929
399742001451	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
399742001452	Mechanosensitive ion channel; Region: MS_channel; pfam00924
399742001453	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
399742001454	GTPase RsgA; Reviewed; Region: PRK12288
399742001455	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
399742001456	RNA binding site [nucleotide binding]; other site
399742001457	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
399742001458	GTPase/Zn-binding domain interface [polypeptide binding]; other site
399742001459	GTP/Mg2+ binding site [chemical binding]; other site
399742001460	G4 box; other site
399742001461	G5 box; other site
399742001462	G1 box; other site
399742001463	Switch I region; other site
399742001464	G2 box; other site
399742001465	G3 box; other site
399742001466	Switch II region; other site
399742001467	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
399742001468	catalytic site [active]
399742001469	putative active site [active]
399742001470	putative substrate binding site [chemical binding]; other site
399742001471	dimer interface [polypeptide binding]; other site
399742001472	epoxyqueuosine reductase; Region: TIGR00276
399742001473	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
399742001474	putative carbohydrate kinase; Provisional; Region: PRK10565
399742001475	Uncharacterized conserved protein [Function unknown]; Region: COG0062
399742001476	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
399742001477	putative substrate binding site [chemical binding]; other site
399742001478	putative ATP binding site [chemical binding]; other site
399742001479	ADP-binding protein; Provisional; Region: PRK10646
399742001480	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
399742001481	AMIN domain; Region: AMIN; pfam11741
399742001482	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
399742001483	active site
399742001484	metal binding site [ion binding]; metal-binding site
399742001485	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
399742001486	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742001487	ATP binding site [chemical binding]; other site
399742001488	Mg2+ binding site [ion binding]; other site
399742001489	G-X-G motif; other site
399742001490	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
399742001491	ATP binding site [chemical binding]; other site
399742001492	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
399742001493	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
399742001494	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
399742001495	bacterial Hfq-like; Region: Hfq; cd01716
399742001496	hexamer interface [polypeptide binding]; other site
399742001497	Sm1 motif; other site
399742001498	RNA binding site [nucleotide binding]; other site
399742001499	Sm2 motif; other site
399742001500	GTPase HflX; Provisional; Region: PRK11058
399742001501	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
399742001502	HflX GTPase family; Region: HflX; cd01878
399742001503	G1 box; other site
399742001504	GTP/Mg2+ binding site [chemical binding]; other site
399742001505	Switch I region; other site
399742001506	G2 box; other site
399742001507	G3 box; other site
399742001508	Switch II region; other site
399742001509	G4 box; other site
399742001510	G5 box; other site
399742001511	FtsH protease regulator HflK; Provisional; Region: PRK10930
399742001512	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
399742001513	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
399742001514	FtsH protease regulator HflC; Provisional; Region: PRK11029
399742001515	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
399742001516	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
399742001517	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
399742001518	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
399742001519	GDP-binding site [chemical binding]; other site
399742001520	ACT binding site; other site
399742001521	IMP binding site; other site
399742001522	Predicted transcriptional regulator [Transcription]; Region: COG1959
399742001523	transcriptional repressor NsrR; Provisional; Region: PRK11014
399742001524	exoribonuclease R; Provisional; Region: PRK11642
399742001525	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
399742001526	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
399742001527	RNB domain; Region: RNB; pfam00773
399742001528	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
399742001529	RNA binding site [nucleotide binding]; other site
399742001530	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
399742001531	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
399742001532	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
399742001533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742001534	metabolite-proton symporter; Region: 2A0106; TIGR00883
399742001535	putative substrate translocation pore; other site
399742001536	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
399742001537	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
399742001538	FAD binding site [chemical binding]; other site
399742001539	substrate binding site [chemical binding]; other site
399742001540	catalytic residues [active]
399742001541	HAMP domain; Region: HAMP; pfam00672
399742001542	dimerization interface [polypeptide binding]; other site
399742001543	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742001544	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742001545	dimer interface [polypeptide binding]; other site
399742001546	putative CheW interface [polypeptide binding]; other site
399742001547	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742001548	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
399742001549	esterase; Provisional; Region: PRK10566
399742001550	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742001551	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742001552	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
399742001553	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
399742001554	dimer interface [polypeptide binding]; other site
399742001555	ssDNA binding site [nucleotide binding]; other site
399742001556	tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742001557	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
399742001558	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
399742001559	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
399742001560	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
399742001561	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
399742001562	EamA-like transporter family; Region: EamA; pfam00892
399742001563	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
399742001564	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
399742001565	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
399742001566	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
399742001567	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
399742001568	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
399742001569	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
399742001570	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
399742001571	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
399742001572	Hemerythrin-like domain; Region: Hr-like; cd12108
399742001573	Fe binding site [ion binding]; other site
399742001574	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
399742001575	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742001576	dimer interface [polypeptide binding]; other site
399742001577	ligand binding site [chemical binding]; other site
399742001578	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742001579	dimerization interface [polypeptide binding]; other site
399742001580	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742001581	dimer interface [polypeptide binding]; other site
399742001582	putative CheW interface [polypeptide binding]; other site
399742001583	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
399742001584	EamA-like transporter family; Region: EamA; pfam00892
399742001585	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742001586	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
399742001587	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742001588	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742001589	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
399742001590	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
399742001591	NADP binding site [chemical binding]; other site
399742001592	Predicted transcriptional regulators [Transcription]; Region: COG1733
399742001593	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
399742001594	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
399742001595	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
399742001596	conserved cys residue [active]
399742001597	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742001598	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
399742001599	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
399742001600	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
399742001601	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742001602	YCII-related domain; Region: YCII; cl00999
399742001603	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
399742001604	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
399742001605	trimer interface [polypeptide binding]; other site
399742001606	active site
399742001607	substrate binding site [chemical binding]; other site
399742001608	CoA binding site [chemical binding]; other site
399742001609	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
399742001610	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
399742001611	active site
399742001612	metal binding site [ion binding]; metal-binding site
399742001613	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
399742001614	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
399742001615	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
399742001616	active site
399742001617	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; cl17398
399742001618	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
399742001619	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
399742001620	Domain of unknown function DUF21; Region: DUF21; pfam01595
399742001621	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
399742001622	Transporter associated domain; Region: CorC_HlyC; smart01091
399742001623	methionine sulfoxide reductase A; Provisional; Region: PRK00058
399742001624	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
399742001625	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
399742001626	Surface antigen; Region: Bac_surface_Ag; pfam01103
399742001627	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
399742001628	Family of unknown function (DUF490); Region: DUF490; pfam04357
399742001629	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
399742001630	putative active site pocket [active]
399742001631	dimerization interface [polypeptide binding]; other site
399742001632	putative catalytic residue [active]
399742001633	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742001634	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742001635	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
399742001636	PapC N-terminal domain; Region: PapC_N; pfam13954
399742001637	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
399742001638	PapC C-terminal domain; Region: PapC_C; pfam13953
399742001639	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
399742001640	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
399742001641	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
399742001642	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742001643	Fimbrial protein; Region: Fimbrial; pfam00419
399742001644	Fimbrial protein; Region: Fimbrial; cl01416
399742001645	Fimbrial protein; Region: Fimbrial; cl01416
399742001646	Fimbrial protein; Region: Fimbrial; pfam00419
399742001647	O-Antigen ligase; Region: Wzy_C; pfam04932
399742001648	Domain of unknown function (DUF3366); Region: DUF3366; pfam11846
399742001649	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
399742001650	dimer interface [polypeptide binding]; other site
399742001651	substrate binding site [chemical binding]; other site
399742001652	metal binding sites [ion binding]; metal-binding site
399742001653	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
399742001654	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
399742001655	putative ligand binding site [chemical binding]; other site
399742001656	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
399742001657	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742001658	Walker A/P-loop; other site
399742001659	ATP binding site [chemical binding]; other site
399742001660	Q-loop/lid; other site
399742001661	ABC transporter signature motif; other site
399742001662	Walker B; other site
399742001663	D-loop; other site
399742001664	H-loop/switch region; other site
399742001665	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742001666	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742001667	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742001668	TM-ABC transporter signature motif; other site
399742001669	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742001670	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742001671	TM-ABC transporter signature motif; other site
399742001672	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742001673	dimer interface [polypeptide binding]; other site
399742001674	ligand binding site [chemical binding]; other site
399742001675	HAMP domain; Region: HAMP; pfam00672
399742001676	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742001677	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742001678	dimer interface [polypeptide binding]; other site
399742001679	putative CheW interface [polypeptide binding]; other site
399742001680	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742001681	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742001682	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
399742001683	AMP binding site [chemical binding]; other site
399742001684	metal binding site [ion binding]; metal-binding site
399742001685	active site
399742001686	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
399742001687	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
399742001688	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
399742001689	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
399742001690	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
399742001691	active site
399742001692	catalytic residues [active]
399742001693	hypothetical protein; Provisional; Region: PRK05255
399742001694	peptidase PmbA; Provisional; Region: PRK11040
399742001695	cytochrome b562; Provisional; Region: PRK15058
399742001696	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
399742001697	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
399742001698	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
399742001699	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
399742001700	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
399742001701	dihydroorotase; Provisional; Region: PRK09237
399742001702	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
399742001703	active site
399742001704	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
399742001705	Protein of unknown function (DUF1341); Region: DUF1341; pfam07071
399742001706	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
399742001707	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
399742001708	HTH domain; Region: HTH_11; pfam08279
399742001709	Mga helix-turn-helix domain; Region: Mga; pfam05043
399742001710	PRD domain; Region: PRD; pfam00874
399742001711	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
399742001712	active site
399742001713	P-loop; other site
399742001714	phosphorylation site [posttranslational modification]
399742001715	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
399742001716	active site
399742001717	phosphorylation site [posttranslational modification]
399742001718	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
399742001719	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
399742001720	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
399742001721	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742001722	FeS/SAM binding site; other site
399742001723	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
399742001724	ATP cone domain; Region: ATP-cone; pfam03477
399742001725	Class III ribonucleotide reductase; Region: RNR_III; cd01675
399742001726	effector binding site; other site
399742001727	active site
399742001728	Zn binding site [ion binding]; other site
399742001729	glycine loop; other site
399742001730	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
399742001731	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
399742001732	Ca binding site [ion binding]; other site
399742001733	active site
399742001734	catalytic site [active]
399742001735	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
399742001736	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
399742001737	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742001738	active site turn [active]
399742001739	phosphorylation site [posttranslational modification]
399742001740	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742001741	trehalose repressor; Provisional; Region: treR; PRK09492
399742001742	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742001743	DNA binding site [nucleotide binding]
399742001744	domain linker motif; other site
399742001745	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
399742001746	dimerization interface [polypeptide binding]; other site
399742001747	ligand binding site [chemical binding]; other site
399742001748	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
399742001749	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
399742001750	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
399742001751	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
399742001752	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
399742001753	Soluble P-type ATPase [General function prediction only]; Region: COG4087
399742001754	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
399742001755	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
399742001756	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
399742001757	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
399742001758	active site
399742001759	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
399742001760	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
399742001761	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
399742001762	homotrimer interaction site [polypeptide binding]; other site
399742001763	putative active site [active]
399742001764	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
399742001765	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
399742001766	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
399742001767	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
399742001768	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
399742001769	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
399742001770	Arginine repressor [Transcription]; Region: ArgR; COG1438
399742001771	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
399742001772	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
399742001773	Predicted membrane protein [Function unknown]; Region: COG1288
399742001774	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
399742001775	ornithine carbamoyltransferase; Validated; Region: PRK02102
399742001776	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
399742001777	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
399742001778	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
399742001779	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
399742001780	putative substrate binding site [chemical binding]; other site
399742001781	nucleotide binding site [chemical binding]; other site
399742001782	nucleotide binding site [chemical binding]; other site
399742001783	homodimer interface [polypeptide binding]; other site
399742001784	arginine deiminase; Provisional; Region: PRK01388
399742001785	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
399742001786	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
399742001787	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
399742001788	inhibitor site; inhibition site
399742001789	active site
399742001790	dimer interface [polypeptide binding]; other site
399742001791	catalytic residue [active]
399742001792	putative dehydratase; Provisional; Region: PRK08211
399742001793	Dehydratase family; Region: ILVD_EDD; cl00340
399742001794	putative symporter YagG; Provisional; Region: PRK09669
399742001795	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
399742001796	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
399742001797	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
399742001798	inhibitor binding site; inhibition site
399742001799	active site
399742001800	Protein of unknown function (DUF1349); Region: DUF1349; cl01397
399742001801	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
399742001802	Transcriptional regulator [Transcription]; Region: IclR; COG1414
399742001803	Bacterial transcriptional regulator; Region: IclR; pfam01614
399742001804	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
399742001805	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
399742001806	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
399742001807	RNase E inhibitor protein; Provisional; Region: PRK11191
399742001808	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
399742001809	active site
399742001810	dinuclear metal binding site [ion binding]; other site
399742001811	dimerization interface [polypeptide binding]; other site
399742001812	integrase; Provisional; Region: PRK09692
399742001813	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
399742001814	active site
399742001815	Int/Topo IB signature motif; other site
399742001816	DNA phosphorothioation-dependent restriction protein DptF; Region: dnd_assoc_3; TIGR03238
399742001817	DNA phosphorothioation-dependent restriction protein DptG; Region: dnd_assoc_1; TIGR03236
399742001818	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
399742001819	AAA-like domain; Region: AAA_10; pfam12846
399742001820	Domain of unknown function DUF87; Region: DUF87; pfam01935
399742001821	Domain of unknown function (DUF1832); Region: DUF1832; pfam08870
399742001822	DNA sulfur modification protein DndD; Region: DNA_S_dndD; TIGR03185
399742001823	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742001824	Walker A/P-loop; other site
399742001825	ATP binding site [chemical binding]; other site
399742001826	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742001827	ABC transporter signature motif; other site
399742001828	Walker B; other site
399742001829	D-loop; other site
399742001830	H-loop/switch region; other site
399742001831	hypothetical protein; Provisional; Region: PRK06850
399742001832	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
399742001833	Active Sites [active]
399742001834	DNA-sulfur modification-associated; Region: DndB; pfam14072
399742001835	DGQHR domain; Region: DGQHR; TIGR03187
399742001836	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
399742001837	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
399742001838	MPN+ (JAMM) motif; other site
399742001839	Zinc-binding site [ion binding]; other site
399742001840	Protein of unknown function (DUF987); Region: DUF987; pfam06174
399742001841	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
399742001842	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
399742001843	Methyltransferase domain; Region: Methyltransf_27; pfam13708
399742001844	Predicted transcriptional regulator [Transcription]; Region: COG3905
399742001845	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
399742001846	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
399742001847	HNH endonuclease; Region: HNH_2; pfam13391
399742001848	Periplasmic pectate lyase; Region: Pectate_lyase_2; pfam06917
399742001849	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
399742001850	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742001851	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742001852	DNA binding residues [nucleotide binding]
399742001853	dimerization interface [polypeptide binding]; other site
399742001854	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
399742001855	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
399742001856	active site
399742001857	HIGH motif; other site
399742001858	dimer interface [polypeptide binding]; other site
399742001859	KMSKS motif; other site
399742001860	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742001861	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
399742001862	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742001863	active site
399742001864	metal binding site [ion binding]; metal-binding site
399742001865	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
399742001866	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
399742001867	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
399742001868	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
399742001869	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
399742001870	oligomer interface [polypeptide binding]; other site
399742001871	active site residues [active]
399742001872	Uncharacterized conserved protein [Function unknown]; Region: COG2850
399742001873	Cupin domain; Region: Cupin_2; cl17218
399742001874	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742001875	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742001876	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
399742001877	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742001878	N-terminal plug; other site
399742001879	ligand-binding site [chemical binding]; other site
399742001880	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
399742001881	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742001882	DNA-binding site [nucleotide binding]; DNA binding site
399742001883	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742001884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742001885	homodimer interface [polypeptide binding]; other site
399742001886	catalytic residue [active]
399742001887	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
399742001888	Domain of unknown function (DUF4282); Region: DUF4282; pfam14110
399742001889	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
399742001890	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742001891	DNA-binding site [nucleotide binding]; DNA binding site
399742001892	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742001893	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742001894	homodimer interface [polypeptide binding]; other site
399742001895	catalytic residue [active]
399742001896	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
399742001897	Uncharacterized conserved protein [Function unknown]; Region: COG2128
399742001898	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742001899	dimerization interface [polypeptide binding]; other site
399742001900	putative DNA binding site [nucleotide binding]; other site
399742001901	putative Zn2+ binding site [ion binding]; other site
399742001902	Autotransporter beta-domain; Region: Autotransporter; smart00869
399742001903	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742001904	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742001905	DNA binding residues [nucleotide binding]
399742001906	dimerization interface [polypeptide binding]; other site
399742001907	transcriptional regulator SlyA; Provisional; Region: PRK03573
399742001908	MarR family; Region: MarR_2; cl17246
399742001909	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
399742001910	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742001911	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742001912	Protein of unknown function (DUF2955); Region: DUF2955; pfam11168
399742001913	Protein of unknown function (DUF445); Region: DUF445; pfam04286
399742001914	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
399742001915	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
399742001916	NAD(P) binding site [chemical binding]; other site
399742001917	catalytic residues [active]
399742001918	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
399742001919	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
399742001920	P-loop, Walker A motif; other site
399742001921	Base recognition motif; other site
399742001922	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
399742001923	Uncharacterized small protein [Function unknown]; Region: COG2879
399742001924	carbon starvation protein A; Provisional; Region: PRK15015
399742001925	Carbon starvation protein CstA; Region: CstA; pfam02554
399742001926	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
399742001927	Predicted transcriptional regulator [Transcription]; Region: COG2378
399742001928	HTH domain; Region: HTH_11; pfam08279
399742001929	WYL domain; Region: WYL; pfam13280
399742001930	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
399742001931	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742001932	dimer interface [polypeptide binding]; other site
399742001933	ligand binding site [chemical binding]; other site
399742001934	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742001935	dimerization interface [polypeptide binding]; other site
399742001936	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742001937	dimer interface [polypeptide binding]; other site
399742001938	putative CheW interface [polypeptide binding]; other site
399742001939	phosphoglycerol transferase I; Provisional; Region: PRK03776
399742001940	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
399742001941	hypothetical protein; Provisional; Region: PRK11667
399742001942	DNA replication protein DnaC; Validated; Region: PRK07952
399742001943	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742001944	Walker A motif; other site
399742001945	ATP binding site [chemical binding]; other site
399742001946	Walker B motif; other site
399742001947	primosomal protein DnaI; Provisional; Region: PRK02854
399742001948	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
399742001949	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
399742001950	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742001951	putative Zn2+ binding site [ion binding]; other site
399742001952	putative DNA binding site [nucleotide binding]; other site
399742001953	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742001954	hypothetical protein; Provisional; Region: PRK09917
399742001955	Uncharacterized conserved protein [Function unknown]; Region: COG2966
399742001956	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
399742001957	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742001958	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742001959	DNA binding residues [nucleotide binding]
399742001960	dimerization interface [polypeptide binding]; other site
399742001961	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
399742001962	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742001963	DNA binding residues [nucleotide binding]
399742001964	dimerization interface [polypeptide binding]; other site
399742001965	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
399742001966	putative deacylase active site [active]
399742001967	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
399742001968	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
399742001969	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
399742001970	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
399742001971	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
399742001972	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742001973	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742001974	metal binding site [ion binding]; metal-binding site
399742001975	active site
399742001976	I-site; other site
399742001977	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
399742001978	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
399742001979	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
399742001980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742001981	S-adenosylmethionine binding site [chemical binding]; other site
399742001982	DNA polymerase III subunit psi; Validated; Region: PRK06856
399742001983	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
399742001984	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
399742001985	dUMP phosphatase; Provisional; Region: PRK09449
399742001986	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742001987	motif II; other site
399742001988	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
399742001989	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
399742001990	G1 box; other site
399742001991	putative GEF interaction site [polypeptide binding]; other site
399742001992	GTP/Mg2+ binding site [chemical binding]; other site
399742001993	Switch I region; other site
399742001994	G2 box; other site
399742001995	G3 box; other site
399742001996	Switch II region; other site
399742001997	G4 box; other site
399742001998	G5 box; other site
399742001999	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
399742002000	periplasmic protein; Provisional; Region: PRK10568
399742002001	BON domain; Region: BON; pfam04972
399742002002	BON domain; Region: BON; pfam04972
399742002003	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
399742002004	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
399742002005	active site
399742002006	nucleophile elbow; other site
399742002007	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
399742002008	active site
399742002009	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
399742002010	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
399742002011	hypothetical protein; Provisional; Region: PRK10977
399742002012	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
399742002013	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
399742002014	intersubunit interface [polypeptide binding]; other site
399742002015	active site
399742002016	catalytic residue [active]
399742002017	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
399742002018	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
399742002019	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
399742002020	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
399742002021	phosphopentomutase; Provisional; Region: PRK05362
399742002022	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
399742002023	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
399742002024	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
399742002025	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
399742002026	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
399742002027	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
399742002028	hypothetical protein; Provisional; Region: PRK11246
399742002029	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
399742002030	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742002031	motif II; other site
399742002032	DNA repair protein RadA; Region: sms; TIGR00416
399742002033	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
399742002034	Walker A motif/ATP binding site; other site
399742002035	ATP binding site [chemical binding]; other site
399742002036	Walker B motif; other site
399742002037	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
399742002038	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742002039	non-specific DNA binding site [nucleotide binding]; other site
399742002040	salt bridge; other site
399742002041	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
399742002042	sequence-specific DNA binding site [nucleotide binding]; other site
399742002043	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
399742002044	active site
399742002045	(T/H)XGH motif; other site
399742002046	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
399742002047	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
399742002048	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
399742002049	putative NAD(P) binding site [chemical binding]; other site
399742002050	dimer interface [polypeptide binding]; other site
399742002051	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742002052	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742002053	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742002054	putative effector binding pocket; other site
399742002055	dimerization interface [polypeptide binding]; other site
399742002056	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
399742002057	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742002058	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742002059	ABC transporter; Region: ABC_tran_2; pfam12848
399742002060	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742002061	lytic murein transglycosylase; Provisional; Region: PRK11619
399742002062	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742002063	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742002064	catalytic residue [active]
399742002065	Trp operon repressor; Provisional; Region: PRK01381
399742002066	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
399742002067	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
399742002068	catalytic core [active]
399742002069	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
399742002070	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742002071	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
399742002072	hypothetical protein; Provisional; Region: PRK10756
399742002073	CreA protein; Region: CreA; pfam05981
399742002074	DNA-binding response regulator CreB; Provisional; Region: PRK11083
399742002075	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742002076	active site
399742002077	phosphorylation site [posttranslational modification]
399742002078	intermolecular recognition site; other site
399742002079	dimerization interface [polypeptide binding]; other site
399742002080	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742002081	DNA binding site [nucleotide binding]
399742002082	sensory histidine kinase CreC; Provisional; Region: PRK11100
399742002083	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742002084	dimer interface [polypeptide binding]; other site
399742002085	phosphorylation site [posttranslational modification]
399742002086	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742002087	ATP binding site [chemical binding]; other site
399742002088	Mg2+ binding site [ion binding]; other site
399742002089	G-X-G motif; other site
399742002090	Inner membrane protein CreD; Region: CreD; pfam06123
399742002091	two-component response regulator; Provisional; Region: PRK11173
399742002092	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742002093	active site
399742002094	phosphorylation site [posttranslational modification]
399742002095	intermolecular recognition site; other site
399742002096	dimerization interface [polypeptide binding]; other site
399742002097	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742002098	DNA binding site [nucleotide binding]
399742002099	putative RNA methyltransferase; Provisional; Region: PRK10433
399742002100	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
399742002101	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
399742002102	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
399742002103	putative catalytic residues [active]
399742002104	putative nucleotide binding site [chemical binding]; other site
399742002105	putative aspartate binding site [chemical binding]; other site
399742002106	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
399742002107	dimer interface [polypeptide binding]; other site
399742002108	putative threonine allosteric regulatory site; other site
399742002109	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
399742002110	putative threonine allosteric regulatory site; other site
399742002111	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
399742002112	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
399742002113	homoserine kinase; Provisional; Region: PRK01212
399742002114	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
399742002115	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
399742002116	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
399742002117	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
399742002118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742002119	catalytic residue [active]
399742002120	hypothetical protein; Validated; Region: PRK02101
399742002121	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
399742002122	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
399742002123	transaldolase-like protein; Provisional; Region: PTZ00411
399742002124	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
399742002125	active site
399742002126	dimer interface [polypeptide binding]; other site
399742002127	catalytic residue [active]
399742002128	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
399742002129	MPT binding site; other site
399742002130	trimer interface [polypeptide binding]; other site
399742002131	metabolite-proton symporter; Region: 2A0106; TIGR00883
399742002132	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742002133	putative substrate translocation pore; other site
399742002134	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
399742002135	intersubunit interface [polypeptide binding]; other site
399742002136	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
399742002137	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742002138	Walker A/P-loop; other site
399742002139	ATP binding site [chemical binding]; other site
399742002140	Q-loop/lid; other site
399742002141	ABC transporter signature motif; other site
399742002142	Walker B; other site
399742002143	D-loop; other site
399742002144	H-loop/switch region; other site
399742002145	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
399742002146	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742002147	ABC-ATPase subunit  interface; other site
399742002148	dimer interface [polypeptide binding]; other site
399742002149	putative PBP binding regions; other site
399742002150	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
399742002151	putative ion selectivity filter; other site
399742002152	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
399742002153	putative pore gating glutamate residue; other site
399742002154	hypothetical protein; Provisional; Region: PRK10659
399742002155	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
399742002156	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
399742002157	nucleotide binding site [chemical binding]; other site
399742002158	chaperone protein DnaJ; Provisional; Region: PRK10767
399742002159	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
399742002160	HSP70 interaction site [polypeptide binding]; other site
399742002161	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
399742002162	substrate binding site [polypeptide binding]; other site
399742002163	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
399742002164	Zn binding sites [ion binding]; other site
399742002165	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
399742002166	dimer interface [polypeptide binding]; other site
399742002167	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
399742002168	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
399742002169	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742002170	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
399742002171	putative dimerization interface [polypeptide binding]; other site
399742002172	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
399742002173	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
399742002174	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
399742002175	active site
399742002176	Riboflavin kinase; Region: Flavokinase; smart00904
399742002177	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
399742002178	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
399742002179	active site
399742002180	HIGH motif; other site
399742002181	nucleotide binding site [chemical binding]; other site
399742002182	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
399742002183	active site
399742002184	KMSKS motif; other site
399742002185	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
399742002186	tRNA binding surface [nucleotide binding]; other site
399742002187	anticodon binding site; other site
399742002188	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
399742002189	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
399742002190	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
399742002191	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
399742002192	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
399742002193	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
399742002194	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742002195	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742002196	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742002197	putative effector binding pocket; other site
399742002198	dimerization interface [polypeptide binding]; other site
399742002199	alanine-tRNA ligase; Region: PLN02961
399742002200	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
399742002201	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
399742002202	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
399742002203	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
399742002204	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
399742002205	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
399742002206	catalytic site [active]
399742002207	subunit interface [polypeptide binding]; other site
399742002208	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
399742002209	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
399742002210	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
399742002211	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
399742002212	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
399742002213	ATP-grasp domain; Region: ATP-grasp_4; cl17255
399742002214	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
399742002215	IMP binding site; other site
399742002216	dimer interface [polypeptide binding]; other site
399742002217	interdomain contacts; other site
399742002218	partial ornithine binding site; other site
399742002219	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
399742002220	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
399742002221	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
399742002222	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742002223	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
399742002224	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
399742002225	TrkA-N domain; Region: TrkA_N; pfam02254
399742002226	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
399742002227	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
399742002228	folate binding site [chemical binding]; other site
399742002229	NADP+ binding site [chemical binding]; other site
399742002230	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
399742002231	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
399742002232	active site
399742002233	metal binding site [ion binding]; metal-binding site
399742002234	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
399742002235	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
399742002236	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
399742002237	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
399742002238	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
399742002239	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
399742002240	SurA N-terminal domain; Region: SurA_N; pfam09312
399742002241	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
399742002242	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
399742002243	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
399742002244	OstA-like protein; Region: OstA; pfam03968
399742002245	Organic solvent tolerance protein; Region: OstA_C; pfam04453
399742002246	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
399742002247	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
399742002248	putative metal binding site [ion binding]; other site
399742002249	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
399742002250	HSP70 interaction site [polypeptide binding]; other site
399742002251	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
399742002252	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
399742002253	active site
399742002254	ATP-dependent helicase HepA; Validated; Region: PRK04914
399742002255	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742002256	ATP binding site [chemical binding]; other site
399742002257	putative Mg++ binding site [ion binding]; other site
399742002258	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742002259	nucleotide binding region [chemical binding]; other site
399742002260	ATP-binding site [chemical binding]; other site
399742002261	DNA polymerase II; Reviewed; Region: PRK05762
399742002262	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
399742002263	active site
399742002264	catalytic site [active]
399742002265	substrate binding site [chemical binding]; other site
399742002266	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
399742002267	active site
399742002268	metal-binding site
399742002269	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
399742002270	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
399742002271	intersubunit interface [polypeptide binding]; other site
399742002272	active site
399742002273	Zn2+ binding site [ion binding]; other site
399742002274	L-arabinose isomerase; Provisional; Region: PRK02929
399742002275	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
399742002276	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
399742002277	trimer interface [polypeptide binding]; other site
399742002278	putative substrate binding site [chemical binding]; other site
399742002279	putative metal binding site [ion binding]; other site
399742002280	ribulokinase; Provisional; Region: PRK04123
399742002281	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
399742002282	N- and C-terminal domain interface [polypeptide binding]; other site
399742002283	active site
399742002284	MgATP binding site [chemical binding]; other site
399742002285	catalytic site [active]
399742002286	metal binding site [ion binding]; metal-binding site
399742002287	carbohydrate binding site [chemical binding]; other site
399742002288	homodimer interface [polypeptide binding]; other site
399742002289	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
399742002290	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742002291	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742002292	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742002293	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
399742002294	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
399742002295	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
399742002296	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
399742002297	Walker A/P-loop; other site
399742002298	ATP binding site [chemical binding]; other site
399742002299	Q-loop/lid; other site
399742002300	ABC transporter signature motif; other site
399742002301	Walker B; other site
399742002302	D-loop; other site
399742002303	H-loop/switch region; other site
399742002304	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
399742002305	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002306	dimer interface [polypeptide binding]; other site
399742002307	conserved gate region; other site
399742002308	putative PBP binding loops; other site
399742002309	ABC-ATPase subunit interface; other site
399742002310	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002311	dimer interface [polypeptide binding]; other site
399742002312	conserved gate region; other site
399742002313	putative PBP binding loops; other site
399742002314	ABC-ATPase subunit interface; other site
399742002315	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
399742002316	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
399742002317	transcriptional regulator SgrR; Provisional; Region: PRK13626
399742002318	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
399742002319	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
399742002320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742002321	sugar efflux transporter; Region: 2A0120; TIGR00899
399742002322	putative substrate translocation pore; other site
399742002323	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
399742002324	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
399742002325	substrate binding site [chemical binding]; other site
399742002326	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
399742002327	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
399742002328	substrate binding site [chemical binding]; other site
399742002329	ligand binding site [chemical binding]; other site
399742002330	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
399742002331	tartrate dehydrogenase; Provisional; Region: PRK08194
399742002332	2-isopropylmalate synthase; Validated; Region: PRK00915
399742002333	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
399742002334	active site
399742002335	catalytic residues [active]
399742002336	metal binding site [ion binding]; metal-binding site
399742002337	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
399742002338	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
399742002339	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742002340	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
399742002341	putative substrate binding pocket [chemical binding]; other site
399742002342	putative dimerization interface [polypeptide binding]; other site
399742002343	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
399742002344	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
399742002345	PYR/PP interface [polypeptide binding]; other site
399742002346	dimer interface [polypeptide binding]; other site
399742002347	TPP binding site [chemical binding]; other site
399742002348	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
399742002349	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
399742002350	TPP-binding site [chemical binding]; other site
399742002351	dimer interface [polypeptide binding]; other site
399742002352	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
399742002353	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
399742002354	putative valine binding site [chemical binding]; other site
399742002355	dimer interface [polypeptide binding]; other site
399742002356	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
399742002357	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
399742002358	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742002359	DNA binding site [nucleotide binding]
399742002360	domain linker motif; other site
399742002361	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
399742002362	dimerization interface [polypeptide binding]; other site
399742002363	ligand binding site [chemical binding]; other site
399742002364	cell division protein MraZ; Reviewed; Region: PRK00326
399742002365	MraZ protein; Region: MraZ; pfam02381
399742002366	MraZ protein; Region: MraZ; pfam02381
399742002367	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
399742002368	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
399742002369	cell division protein FtsL; Provisional; Region: PRK10772
399742002370	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
399742002371	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
399742002372	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
399742002373	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
399742002374	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
399742002375	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
399742002376	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
399742002377	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
399742002378	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
399742002379	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
399742002380	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
399742002381	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
399742002382	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
399742002383	Mg++ binding site [ion binding]; other site
399742002384	putative catalytic motif [active]
399742002385	putative substrate binding site [chemical binding]; other site
399742002386	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
399742002387	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
399742002388	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
399742002389	cell division protein FtsW; Provisional; Region: PRK10774
399742002390	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
399742002391	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
399742002392	active site
399742002393	homodimer interface [polypeptide binding]; other site
399742002394	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
399742002395	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
399742002396	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
399742002397	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
399742002398	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
399742002399	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
399742002400	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
399742002401	cell division protein FtsQ; Provisional; Region: PRK10775
399742002402	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
399742002403	Cell division protein FtsQ; Region: FtsQ; pfam03799
399742002404	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
399742002405	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742002406	Cell division protein FtsA; Region: FtsA; pfam14450
399742002407	cell division protein FtsZ; Validated; Region: PRK09330
399742002408	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
399742002409	nucleotide binding site [chemical binding]; other site
399742002410	SulA interaction site; other site
399742002411	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
399742002412	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
399742002413	SecA regulator SecM; Provisional; Region: PRK02943
399742002414	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
399742002415	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
399742002416	SEC-C motif; Region: SEC-C; pfam02810
399742002417	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
399742002418	active site
399742002419	8-oxo-dGMP binding site [chemical binding]; other site
399742002420	nudix motif; other site
399742002421	metal binding site [ion binding]; metal-binding site
399742002422	DNA gyrase inhibitor; Reviewed; Region: PRK00418
399742002423	hypothetical protein; Provisional; Region: PRK05287
399742002424	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
399742002425	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
399742002426	CoA-binding site [chemical binding]; other site
399742002427	ATP-binding [chemical binding]; other site
399742002428	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
399742002429	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
399742002430	active site
399742002431	type IV pilin biogenesis protein; Provisional; Region: PRK10573
399742002432	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
399742002433	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
399742002434	hypothetical protein; Provisional; Region: PRK10436
399742002435	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
399742002436	Walker A motif; other site
399742002437	ATP binding site [chemical binding]; other site
399742002438	Walker B motif; other site
399742002439	putative major pilin subunit; Provisional; Region: PRK10574
399742002440	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
399742002441	Pilin (bacterial filament); Region: Pilin; pfam00114
399742002442	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
399742002443	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
399742002444	dimerization interface [polypeptide binding]; other site
399742002445	active site
399742002446	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
399742002447	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
399742002448	amidase catalytic site [active]
399742002449	Zn binding residues [ion binding]; other site
399742002450	substrate binding site [chemical binding]; other site
399742002451	regulatory protein AmpE; Provisional; Region: PRK10987
399742002452	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
399742002453	active site
399742002454	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
399742002455	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742002456	putative substrate translocation pore; other site
399742002457	aromatic amino acid transporter; Provisional; Region: PRK10238
399742002458	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
399742002459	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742002460	DNA-binding site [nucleotide binding]; DNA binding site
399742002461	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
399742002462	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
399742002463	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
399742002464	dimer interface [polypeptide binding]; other site
399742002465	TPP-binding site [chemical binding]; other site
399742002466	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
399742002467	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
399742002468	E3 interaction surface; other site
399742002469	lipoyl attachment site [posttranslational modification]; other site
399742002470	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
399742002471	E3 interaction surface; other site
399742002472	lipoyl attachment site [posttranslational modification]; other site
399742002473	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
399742002474	E3 interaction surface; other site
399742002475	lipoyl attachment site [posttranslational modification]; other site
399742002476	e3 binding domain; Region: E3_binding; pfam02817
399742002477	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
399742002478	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
399742002479	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
399742002480	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742002481	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
399742002482	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
399742002483	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
399742002484	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
399742002485	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
399742002486	substrate binding site [chemical binding]; other site
399742002487	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
399742002488	substrate binding site [chemical binding]; other site
399742002489	ligand binding site [chemical binding]; other site
399742002490	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
399742002491	HNH endonuclease; Region: HNH; pfam01844
399742002492	active site
399742002493	hypothetical protein; Provisional; Region: PRK05248
399742002494	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
399742002495	spermidine synthase; Provisional; Region: PRK00811
399742002496	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742002497	S-adenosylmethionine binding site [chemical binding]; other site
399742002498	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
399742002499	multicopper oxidase; Provisional; Region: PRK10965
399742002500	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
399742002501	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
399742002502	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
399742002503	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
399742002504	Trp docking motif [polypeptide binding]; other site
399742002505	putative active site [active]
399742002506	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742002507	active site
399742002508	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
399742002509	active site clefts [active]
399742002510	zinc binding site [ion binding]; other site
399742002511	dimer interface [polypeptide binding]; other site
399742002512	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
399742002513	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
399742002514	Walker A/P-loop; other site
399742002515	ATP binding site [chemical binding]; other site
399742002516	Q-loop/lid; other site
399742002517	ABC transporter signature motif; other site
399742002518	Walker B; other site
399742002519	D-loop; other site
399742002520	H-loop/switch region; other site
399742002521	inner membrane transport permease; Provisional; Region: PRK15066
399742002522	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
399742002523	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
399742002524	active pocket/dimerization site; other site
399742002525	active site
399742002526	phosphorylation site [posttranslational modification]
399742002527	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
399742002528	putative active site [active]
399742002529	putative metal binding site [ion binding]; other site
399742002530	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
399742002531	tetramerization interface [polypeptide binding]; other site
399742002532	active site
399742002533	pantoate--beta-alanine ligase; Region: panC; TIGR00018
399742002534	Pantoate-beta-alanine ligase; Region: PanC; cd00560
399742002535	active site
399742002536	ATP-binding site [chemical binding]; other site
399742002537	pantoate-binding site; other site
399742002538	HXXH motif; other site
399742002539	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
399742002540	oligomerization interface [polypeptide binding]; other site
399742002541	active site
399742002542	metal binding site [ion binding]; metal-binding site
399742002543	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
399742002544	catalytic center binding site [active]
399742002545	ATP binding site [chemical binding]; other site
399742002546	poly(A) polymerase; Region: pcnB; TIGR01942
399742002547	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
399742002548	active site
399742002549	NTP binding site [chemical binding]; other site
399742002550	metal binding triad [ion binding]; metal-binding site
399742002551	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
399742002552	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
399742002553	glutamyl-queuosine tRNA(Asp) synthetase; Region: queuosine_YadB; TIGR03838
399742002554	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
399742002555	active site
399742002556	HIGH motif; other site
399742002557	nucleotide binding site [chemical binding]; other site
399742002558	KMSKS motif; other site
399742002559	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
399742002560	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
399742002561	2'-5' RNA ligase; Provisional; Region: PRK15124
399742002562	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
399742002563	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
399742002564	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742002565	ATP binding site [chemical binding]; other site
399742002566	putative Mg++ binding site [ion binding]; other site
399742002567	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742002568	nucleotide binding region [chemical binding]; other site
399742002569	ATP-binding site [chemical binding]; other site
399742002570	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
399742002571	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
399742002572	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
399742002573	Transglycosylase; Region: Transgly; pfam00912
399742002574	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
399742002575	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
399742002576	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742002577	N-terminal plug; other site
399742002578	ligand-binding site [chemical binding]; other site
399742002579	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
399742002580	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742002581	Walker A/P-loop; other site
399742002582	ATP binding site [chemical binding]; other site
399742002583	Q-loop/lid; other site
399742002584	ABC transporter signature motif; other site
399742002585	Walker B; other site
399742002586	D-loop; other site
399742002587	H-loop/switch region; other site
399742002588	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
399742002589	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
399742002590	siderophore binding site; other site
399742002591	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
399742002592	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742002593	ABC-ATPase subunit  interface; other site
399742002594	dimer interface [polypeptide binding]; other site
399742002595	putative PBP binding regions; other site
399742002596	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742002597	ABC-ATPase subunit  interface; other site
399742002598	dimer interface [polypeptide binding]; other site
399742002599	putative PBP binding regions; other site
399742002600	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
399742002601	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742002602	inhibitor-cofactor binding pocket; inhibition site
399742002603	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742002604	catalytic residue [active]
399742002605	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
399742002606	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
399742002607	Cl- selectivity filter; other site
399742002608	Cl- binding residues [ion binding]; other site
399742002609	pore gating glutamate residue; other site
399742002610	dimer interface [polypeptide binding]; other site
399742002611	H+/Cl- coupling transport residue; other site
399742002612	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
399742002613	hypothetical protein; Provisional; Region: PRK10578
399742002614	UPF0126 domain; Region: UPF0126; pfam03458
399742002615	UPF0126 domain; Region: UPF0126; pfam03458
399742002616	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
399742002617	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
399742002618	cobalamin binding residues [chemical binding]; other site
399742002619	putative BtuC binding residues; other site
399742002620	dimer interface [polypeptide binding]; other site
399742002621	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
399742002622	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
399742002623	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
399742002624	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742002625	Zn2+ binding site [ion binding]; other site
399742002626	Mg2+ binding site [ion binding]; other site
399742002627	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
399742002628	serine endoprotease; Provisional; Region: PRK10942
399742002629	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
399742002630	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
399742002631	protein binding site [polypeptide binding]; other site
399742002632	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
399742002633	protein binding site [polypeptide binding]; other site
399742002634	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
399742002635	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
399742002636	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
399742002637	hypothetical protein; Provisional; Region: PRK13677
399742002638	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
399742002639	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
399742002640	trimer interface [polypeptide binding]; other site
399742002641	active site
399742002642	substrate binding site [chemical binding]; other site
399742002643	CoA binding site [chemical binding]; other site
399742002644	PII uridylyl-transferase; Provisional; Region: PRK05007
399742002645	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
399742002646	metal binding triad; other site
399742002647	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
399742002648	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742002649	Zn2+ binding site [ion binding]; other site
399742002650	Mg2+ binding site [ion binding]; other site
399742002651	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
399742002652	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
399742002653	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
399742002654	active site
399742002655	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
399742002656	rRNA interaction site [nucleotide binding]; other site
399742002657	S8 interaction site; other site
399742002658	putative laminin-1 binding site; other site
399742002659	elongation factor Ts; Provisional; Region: tsf; PRK09377
399742002660	UBA/TS-N domain; Region: UBA; pfam00627
399742002661	Elongation factor TS; Region: EF_TS; pfam00889
399742002662	Elongation factor TS; Region: EF_TS; pfam00889
399742002663	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
399742002664	putative nucleotide binding site [chemical binding]; other site
399742002665	uridine monophosphate binding site [chemical binding]; other site
399742002666	homohexameric interface [polypeptide binding]; other site
399742002667	ribosome recycling factor; Reviewed; Region: frr; PRK00083
399742002668	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
399742002669	hinge region; other site
399742002670	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
399742002671	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
399742002672	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
399742002673	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
399742002674	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
399742002675	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
399742002676	catalytic residue [active]
399742002677	putative FPP diphosphate  binding site; other site
399742002678	putative FPP binding hydrophobic cleft; other site
399742002679	dimer interface [polypeptide binding]; other site
399742002680	putative IPP diphosphate binding site; other site
399742002681	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
399742002682	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
399742002683	zinc metallopeptidase RseP; Provisional; Region: PRK10779
399742002684	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
399742002685	active site
399742002686	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
399742002687	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
399742002688	protein binding site [polypeptide binding]; other site
399742002689	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
399742002690	putative substrate binding region [chemical binding]; other site
399742002691	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
399742002692	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
399742002693	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
399742002694	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
399742002695	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
399742002696	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
399742002697	Surface antigen; Region: Bac_surface_Ag; pfam01103
399742002698	periplasmic chaperone; Provisional; Region: PRK10780
399742002699	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
399742002700	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
399742002701	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
399742002702	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
399742002703	trimer interface [polypeptide binding]; other site
399742002704	active site
399742002705	UDP-GlcNAc binding site [chemical binding]; other site
399742002706	lipid binding site [chemical binding]; lipid-binding site
399742002707	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
399742002708	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
399742002709	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
399742002710	active site
399742002711	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
399742002712	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
399742002713	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
399742002714	RNA/DNA hybrid binding site [nucleotide binding]; other site
399742002715	active site
399742002716	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
399742002717	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
399742002718	putative active site [active]
399742002719	putative PHP Thumb interface [polypeptide binding]; other site
399742002720	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
399742002721	generic binding surface II; other site
399742002722	generic binding surface I; other site
399742002723	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
399742002724	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
399742002725	lysine decarboxylase LdcC; Provisional; Region: PRK15399
399742002726	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
399742002727	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
399742002728	homodimer interface [polypeptide binding]; other site
399742002729	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742002730	catalytic residue [active]
399742002731	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
399742002732	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
399742002733	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742002734	putative metal binding site [ion binding]; other site
399742002735	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
399742002736	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
399742002737	Ligand Binding Site [chemical binding]; other site
399742002738	TilS substrate binding domain; Region: TilS; pfam09179
399742002739	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
399742002740	Rho-binding antiterminator; Provisional; Region: PRK11625
399742002741	hypothetical protein; Provisional; Region: PRK04964
399742002742	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
399742002743	hypothetical protein; Provisional; Region: PRK09256
399742002744	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
399742002745	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
399742002746	NlpE N-terminal domain; Region: NlpE; pfam04170
399742002747	prolyl-tRNA synthetase; Provisional; Region: PRK09194
399742002748	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
399742002749	dimer interface [polypeptide binding]; other site
399742002750	motif 1; other site
399742002751	active site
399742002752	motif 2; other site
399742002753	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
399742002754	putative deacylase active site [active]
399742002755	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
399742002756	active site
399742002757	motif 3; other site
399742002758	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
399742002759	anticodon binding site; other site
399742002760	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
399742002761	homodimer interaction site [polypeptide binding]; other site
399742002762	cofactor binding site; other site
399742002763	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
399742002764	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
399742002765	lipoprotein, YaeC family; Region: TIGR00363
399742002766	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002767	dimer interface [polypeptide binding]; other site
399742002768	conserved gate region; other site
399742002769	ABC-ATPase subunit interface; other site
399742002770	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
399742002771	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
399742002772	Walker A/P-loop; other site
399742002773	ATP binding site [chemical binding]; other site
399742002774	Q-loop/lid; other site
399742002775	ABC transporter signature motif; other site
399742002776	Walker B; other site
399742002777	D-loop; other site
399742002778	H-loop/switch region; other site
399742002779	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
399742002780	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
399742002781	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742002782	active site
399742002783	motif I; other site
399742002784	motif II; other site
399742002785	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
399742002786	Transposase; Region: HTH_Tnp_1; cl17663
399742002787	putative transposase OrfB; Reviewed; Region: PHA02517
399742002788	HTH-like domain; Region: HTH_21; pfam13276
399742002789	Integrase core domain; Region: rve; pfam00665
399742002790	Integrase core domain; Region: rve_2; pfam13333
399742002791	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742002792	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742002793	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
399742002794	putative effector binding pocket; other site
399742002795	dimerization interface [polypeptide binding]; other site
399742002796	hypothetical protein; Provisional; Region: PRK05421
399742002797	putative catalytic site [active]
399742002798	putative metal binding site [ion binding]; other site
399742002799	putative phosphate binding site [ion binding]; other site
399742002800	putative catalytic site [active]
399742002801	putative phosphate binding site [ion binding]; other site
399742002802	putative metal binding site [ion binding]; other site
399742002803	Methyltransferase domain; Region: Methyltransf_23; pfam13489
399742002804	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742002805	S-adenosylmethionine binding site [chemical binding]; other site
399742002806	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
399742002807	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742002808	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742002809	catalytic residue [active]
399742002810	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742002811	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742002812	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
399742002813	Methyltransferase domain; Region: Methyltransf_11; pfam08241
399742002814	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
399742002815	RNA/DNA hybrid binding site [nucleotide binding]; other site
399742002816	active site
399742002817	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
399742002818	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
399742002819	active site
399742002820	catalytic site [active]
399742002821	substrate binding site [chemical binding]; other site
399742002822	Transcriptional regulators [Transcription]; Region: FadR; COG2186
399742002823	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742002824	DNA-binding site [nucleotide binding]; DNA binding site
399742002825	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
399742002826	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
399742002827	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742002828	Walker A/P-loop; other site
399742002829	ATP binding site [chemical binding]; other site
399742002830	Q-loop/lid; other site
399742002831	ABC transporter signature motif; other site
399742002832	Walker B; other site
399742002833	D-loop; other site
399742002834	H-loop/switch region; other site
399742002835	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
399742002836	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
399742002837	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742002838	Walker A/P-loop; other site
399742002839	ATP binding site [chemical binding]; other site
399742002840	Q-loop/lid; other site
399742002841	ABC transporter signature motif; other site
399742002842	Walker B; other site
399742002843	D-loop; other site
399742002844	H-loop/switch region; other site
399742002845	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
399742002846	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742002847	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_5; cd08511
399742002848	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
399742002849	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002850	dimer interface [polypeptide binding]; other site
399742002851	conserved gate region; other site
399742002852	putative PBP binding loops; other site
399742002853	ABC-ATPase subunit interface; other site
399742002854	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
399742002855	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002856	dimer interface [polypeptide binding]; other site
399742002857	conserved gate region; other site
399742002858	putative PBP binding loops; other site
399742002859	ABC-ATPase subunit interface; other site
399742002860	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
399742002861	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
399742002862	C-N hydrolase family amidase; Provisional; Region: PRK10438
399742002863	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
399742002864	putative active site [active]
399742002865	catalytic triad [active]
399742002866	dimer interface [polypeptide binding]; other site
399742002867	multimer interface [polypeptide binding]; other site
399742002868	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
399742002869	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
399742002870	active site
399742002871	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
399742002872	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
399742002873	dimer interface [polypeptide binding]; other site
399742002874	active site
399742002875	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
399742002876	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
399742002877	putative active site [active]
399742002878	putative dimer interface [polypeptide binding]; other site
399742002879	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
399742002880	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
399742002881	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
399742002882	active site
399742002883	DNA polymerase IV; Validated; Region: PRK02406
399742002884	DNA binding site [nucleotide binding]
399742002885	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
399742002886	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
399742002887	metal binding site [ion binding]; metal-binding site
399742002888	dimer interface [polypeptide binding]; other site
399742002889	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742002890	active site
399742002891	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
399742002892	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
399742002893	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742002894	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
399742002895	trimer interface [polypeptide binding]; other site
399742002896	eyelet of channel; other site
399742002897	gamma-glutamyl kinase; Provisional; Region: PRK05429
399742002898	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
399742002899	nucleotide binding site [chemical binding]; other site
399742002900	homotetrameric interface [polypeptide binding]; other site
399742002901	putative phosphate binding site [ion binding]; other site
399742002902	putative allosteric binding site; other site
399742002903	PUA domain; Region: PUA; pfam01472
399742002904	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
399742002905	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
399742002906	putative catalytic cysteine [active]
399742002907	integrase; Provisional; Region: int; PHA02601
399742002908	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
399742002909	Int/Topo IB signature motif; other site
399742002910	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
399742002911	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
399742002912	AAA domain; Region: AAA_22; pfam13401
399742002913	exodeoxyribonuclease X; Provisional; Region: PRK07983
399742002914	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
399742002915	active site
399742002916	catalytic site [active]
399742002917	substrate binding site [chemical binding]; other site
399742002918	acetyl-CoA carboxylase beta subunit; Reviewed; Region: accD; CHL00174
399742002919	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
399742002920	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742002921	non-specific DNA binding site [nucleotide binding]; other site
399742002922	salt bridge; other site
399742002923	sequence-specific DNA binding site [nucleotide binding]; other site
399742002924	Predicted transcriptional regulator [Transcription]; Region: COG2932
399742002925	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742002926	Catalytic site [active]
399742002927	Bacteriophage CII protein; Region: Phage_CII; pfam05269
399742002928	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
399742002929	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
399742002930	phage replicative helicase, DnaB family, HK022 subfamily; Region: phage_DnaB; TIGR03600
399742002931	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
399742002932	Walker A motif; other site
399742002933	ATP binding site [chemical binding]; other site
399742002934	Walker B motif; other site
399742002935	Tup N-terminal; Region: Tup_N; pfam08581
399742002936	NinB protein; Region: NinB; pfam05772
399742002937	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
399742002938	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
399742002939	Protein of unknown function DUF115; Region: MAF_flag10; cl17471
399742002940	Methyltransferase domain; Region: Methyltransf_23; pfam13489
399742002941	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
399742002942	catalytic residues [active]
399742002943	Uncharacterized conserved protein (DUF2280); Region: DUF2280; pfam10045
399742002944	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
399742002945	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3566
399742002946	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
399742002947	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
399742002948	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
399742002949	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
399742002950	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
399742002951	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742002952	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742002953	catalytic residue [active]
399742002954	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
399742002955	Baseplate J-like protein; Region: Baseplate_J; cl01294
399742002956	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
399742002957	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
399742002958	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
399742002959	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
399742002960	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
399742002961	catalytic site [active]
399742002962	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742002963	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
399742002964	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742002965	putative substrate translocation pore; other site
399742002966	POT family; Region: PTR2; cl17359
399742002967	Methyltransferase domain; Region: Methyltransf_23; pfam13489
399742002968	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742002969	S-adenosylmethionine binding site [chemical binding]; other site
399742002970	GAF domain; Region: GAF_3; pfam13492
399742002971	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742002972	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742002973	metal binding site [ion binding]; metal-binding site
399742002974	active site
399742002975	I-site; other site
399742002976	Domain of unknown function DUF20; Region: UPF0118; pfam01594
399742002977	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
399742002978	S-methylmethionine transporter; Provisional; Region: PRK11387
399742002979	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
399742002980	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
399742002981	Protein of unknown function (DUF796); Region: DUF796; pfam05638
399742002982	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
399742002983	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
399742002984	Walker A/P-loop; other site
399742002985	ATP binding site [chemical binding]; other site
399742002986	Q-loop/lid; other site
399742002987	ABC transporter signature motif; other site
399742002988	Walker B; other site
399742002989	D-loop; other site
399742002990	H-loop/switch region; other site
399742002991	TOBE domain; Region: TOBE_2; pfam08402
399742002992	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
399742002993	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002994	dimer interface [polypeptide binding]; other site
399742002995	conserved gate region; other site
399742002996	putative PBP binding loops; other site
399742002997	ABC-ATPase subunit interface; other site
399742002998	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742002999	dimer interface [polypeptide binding]; other site
399742003000	conserved gate region; other site
399742003001	putative PBP binding loops; other site
399742003002	ABC-ATPase subunit interface; other site
399742003003	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
399742003004	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
399742003005	regulatory protein UhpC; Provisional; Region: PRK11663
399742003006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003007	putative substrate translocation pore; other site
399742003008	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
399742003009	MASE1; Region: MASE1; pfam05231
399742003010	Histidine kinase; Region: HisKA_3; pfam07730
399742003011	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742003012	ATP binding site [chemical binding]; other site
399742003013	Mg2+ binding site [ion binding]; other site
399742003014	G-X-G motif; other site
399742003015	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742003016	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742003017	active site
399742003018	phosphorylation site [posttranslational modification]
399742003019	intermolecular recognition site; other site
399742003020	dimerization interface [polypeptide binding]; other site
399742003021	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742003022	DNA binding residues [nucleotide binding]
399742003023	dimerization interface [polypeptide binding]; other site
399742003024	Helix-turn-helix domain; Region: HTH_28; pfam13518
399742003025	putative transposase OrfB; Reviewed; Region: PHA02517
399742003026	Homeodomain-like domain; Region: HTH_32; pfam13565
399742003027	Integrase core domain; Region: rve; pfam00665
399742003028	Integrase core domain; Region: rve_3; pfam13683
399742003029	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
399742003030	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742003031	substrate binding pocket [chemical binding]; other site
399742003032	membrane-bound complex binding site; other site
399742003033	hinge residues; other site
399742003034	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
399742003035	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
399742003036	Walker A/P-loop; other site
399742003037	ATP binding site [chemical binding]; other site
399742003038	Q-loop/lid; other site
399742003039	ABC transporter signature motif; other site
399742003040	Walker B; other site
399742003041	D-loop; other site
399742003042	H-loop/switch region; other site
399742003043	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
399742003044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742003045	dimer interface [polypeptide binding]; other site
399742003046	conserved gate region; other site
399742003047	putative PBP binding loops; other site
399742003048	ABC-ATPase subunit interface; other site
399742003049	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
399742003050	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
399742003051	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
399742003052	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
399742003053	putative acyl-acceptor binding pocket; other site
399742003054	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
399742003055	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
399742003056	dimer interface [polypeptide binding]; other site
399742003057	active site
399742003058	Schiff base residues; other site
399742003059	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
399742003060	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
399742003061	Isochorismatase family; Region: Isochorismatase; pfam00857
399742003062	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
399742003063	catalytic triad [active]
399742003064	conserved cis-peptide bond; other site
399742003065	microcin B17 transporter; Reviewed; Region: PRK11098
399742003066	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
399742003067	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
399742003068	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
399742003069	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
399742003070	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
399742003071	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
399742003072	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
399742003073	drug efflux system protein MdtG; Provisional; Region: PRK09874
399742003074	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003075	putative substrate translocation pore; other site
399742003076	anti-RssB factor; Provisional; Region: PRK10244
399742003077	alkaline phosphatase; Provisional; Region: PRK10518
399742003078	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
399742003079	dimer interface [polypeptide binding]; other site
399742003080	active site
399742003081	hypothetical protein; Provisional; Region: PRK11505
399742003082	psiF repeat; Region: PsiF_repeat; pfam07769
399742003083	psiF repeat; Region: PsiF_repeat; pfam07769
399742003084	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
399742003085	MASE2 domain; Region: MASE2; pfam05230
399742003086	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742003087	metal binding site [ion binding]; metal-binding site
399742003088	active site
399742003089	I-site; other site
399742003090	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
399742003091	pyrroline-5-carboxylate reductase; Region: PLN02688
399742003092	hypothetical protein; Validated; Region: PRK00124
399742003093	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
399742003094	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
399742003095	ADP binding site [chemical binding]; other site
399742003096	magnesium binding site [ion binding]; other site
399742003097	putative shikimate binding site; other site
399742003098	hypothetical protein; Provisional; Region: PRK10380
399742003099	hypothetical protein; Provisional; Region: PRK10481
399742003100	hypothetical protein; Provisional; Region: PRK10579
399742003101	recombination associated protein; Reviewed; Region: rdgC; PRK00321
399742003102	fructokinase; Reviewed; Region: PRK09557
399742003103	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742003104	nucleotide binding site [chemical binding]; other site
399742003105	exonuclease subunit SbcC; Provisional; Region: PRK10246
399742003106	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742003107	Walker A/P-loop; other site
399742003108	ATP binding site [chemical binding]; other site
399742003109	Q-loop/lid; other site
399742003110	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742003111	ABC transporter signature motif; other site
399742003112	Walker B; other site
399742003113	D-loop; other site
399742003114	H-loop/switch region; other site
399742003115	exonuclease subunit SbcD; Provisional; Region: PRK10966
399742003116	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
399742003117	active site
399742003118	metal binding site [ion binding]; metal-binding site
399742003119	DNA binding site [nucleotide binding]
399742003120	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
399742003121	transcriptional regulator PhoB; Provisional; Region: PRK10161
399742003122	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742003123	active site
399742003124	phosphorylation site [posttranslational modification]
399742003125	intermolecular recognition site; other site
399742003126	dimerization interface [polypeptide binding]; other site
399742003127	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742003128	DNA binding site [nucleotide binding]
399742003129	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
399742003130	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
399742003131	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742003132	putative active site [active]
399742003133	heme pocket [chemical binding]; other site
399742003134	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742003135	dimer interface [polypeptide binding]; other site
399742003136	phosphorylation site [posttranslational modification]
399742003137	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742003138	ATP binding site [chemical binding]; other site
399742003139	Mg2+ binding site [ion binding]; other site
399742003140	G-X-G motif; other site
399742003141	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
399742003142	putative proline-specific permease; Provisional; Region: proY; PRK10580
399742003143	Spore germination protein; Region: Spore_permease; cl17796
399742003144	maltodextrin glucosidase; Provisional; Region: PRK10785
399742003145	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
399742003146	homodimer interface [polypeptide binding]; other site
399742003147	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
399742003148	active site
399742003149	homodimer interface [polypeptide binding]; other site
399742003150	catalytic site [active]
399742003151	peroxidase; Provisional; Region: PRK15000
399742003152	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
399742003153	dimer interface [polypeptide binding]; other site
399742003154	decamer (pentamer of dimers) interface [polypeptide binding]; other site
399742003155	catalytic triad [active]
399742003156	peroxidatic and resolving cysteines [active]
399742003157	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
399742003158	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
399742003159	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
399742003160	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
399742003161	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
399742003162	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
399742003163	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
399742003164	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
399742003165	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
399742003166	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
399742003167	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
399742003168	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
399742003169	Protein export membrane protein; Region: SecD_SecF; pfam02355
399742003170	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
399742003171	hypothetical protein; Provisional; Region: PRK11530
399742003172	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
399742003173	ATP cone domain; Region: ATP-cone; pfam03477
399742003174	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
399742003175	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
399742003176	catalytic motif [active]
399742003177	Zn binding site [ion binding]; other site
399742003178	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
399742003179	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
399742003180	homopentamer interface [polypeptide binding]; other site
399742003181	active site
399742003182	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
399742003183	putative RNA binding site [nucleotide binding]; other site
399742003184	thiamine monophosphate kinase; Provisional; Region: PRK05731
399742003185	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
399742003186	ATP binding site [chemical binding]; other site
399742003187	dimerization interface [polypeptide binding]; other site
399742003188	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742003189	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742003190	active site
399742003191	catalytic tetrad [active]
399742003192	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
399742003193	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
399742003194	TPP-binding site; other site
399742003195	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
399742003196	PYR/PP interface [polypeptide binding]; other site
399742003197	dimer interface [polypeptide binding]; other site
399742003198	TPP binding site [chemical binding]; other site
399742003199	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
399742003200	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
399742003201	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
399742003202	substrate binding pocket [chemical binding]; other site
399742003203	chain length determination region; other site
399742003204	substrate-Mg2+ binding site; other site
399742003205	catalytic residues [active]
399742003206	aspartate-rich region 1; other site
399742003207	active site lid residues [active]
399742003208	aspartate-rich region 2; other site
399742003209	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
399742003210	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
399742003211	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
399742003212	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
399742003213	Ligand Binding Site [chemical binding]; other site
399742003214	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
399742003215	active site residue [active]
399742003216	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
399742003217	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
399742003218	conserved cys residue [active]
399742003219	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
399742003220	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
399742003221	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
399742003222	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
399742003223	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
399742003224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003225	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742003226	putative substrate translocation pore; other site
399742003227	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
399742003228	UbiA prenyltransferase family; Region: UbiA; pfam01040
399742003229	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
399742003230	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
399742003231	Subunit I/III interface [polypeptide binding]; other site
399742003232	Subunit III/IV interface [polypeptide binding]; other site
399742003233	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
399742003234	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
399742003235	D-pathway; other site
399742003236	Putative ubiquinol binding site [chemical binding]; other site
399742003237	Low-spin heme (heme b) binding site [chemical binding]; other site
399742003238	Putative water exit pathway; other site
399742003239	Binuclear center (heme o3/CuB) [ion binding]; other site
399742003240	K-pathway; other site
399742003241	Putative proton exit pathway; other site
399742003242	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
399742003243	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
399742003244	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
399742003245	muropeptide transporter; Reviewed; Region: ampG; PRK11902
399742003246	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003247	putative substrate translocation pore; other site
399742003248	hypothetical protein; Provisional; Region: PRK11627
399742003249	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
399742003250	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
399742003251	transcriptional regulator BolA; Provisional; Region: PRK11628
399742003252	trigger factor; Provisional; Region: tig; PRK01490
399742003253	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
399742003254	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
399742003255	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
399742003256	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
399742003257	oligomer interface [polypeptide binding]; other site
399742003258	active site residues [active]
399742003259	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
399742003260	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
399742003261	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742003262	Walker A motif; other site
399742003263	ATP binding site [chemical binding]; other site
399742003264	Walker B motif; other site
399742003265	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
399742003266	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
399742003267	Found in ATP-dependent protease La (LON); Region: LON; smart00464
399742003268	Found in ATP-dependent protease La (LON); Region: LON; smart00464
399742003269	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742003270	Walker A motif; other site
399742003271	ATP binding site [chemical binding]; other site
399742003272	Walker B motif; other site
399742003273	arginine finger; other site
399742003274	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
399742003275	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
399742003276	IHF dimer interface [polypeptide binding]; other site
399742003277	IHF - DNA interface [nucleotide binding]; other site
399742003278	periplasmic folding chaperone; Provisional; Region: PRK10788
399742003279	SurA N-terminal domain; Region: SurA_N_3; cl07813
399742003280	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
399742003281	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
399742003282	minor groove reading motif; other site
399742003283	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
399742003284	helix-hairpin-helix signature motif; other site
399742003285	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
399742003286	active site
399742003287	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
399742003288	Ligand Binding Site [chemical binding]; other site
399742003289	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
399742003290	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
399742003291	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
399742003292	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
399742003293	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742003294	active site
399742003295	motif I; other site
399742003296	motif II; other site
399742003297	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
399742003298	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
399742003299	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
399742003300	catalytic residue [active]
399742003301	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
399742003302	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742003303	putative DNA binding site [nucleotide binding]; other site
399742003304	putative Zn2+ binding site [ion binding]; other site
399742003305	AsnC family; Region: AsnC_trans_reg; pfam01037
399742003306	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
399742003307	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
399742003308	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742003309	Walker A/P-loop; other site
399742003310	ATP binding site [chemical binding]; other site
399742003311	Q-loop/lid; other site
399742003312	ABC transporter signature motif; other site
399742003313	Walker B; other site
399742003314	D-loop; other site
399742003315	H-loop/switch region; other site
399742003316	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
399742003317	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
399742003318	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
399742003319	Walker A/P-loop; other site
399742003320	ATP binding site [chemical binding]; other site
399742003321	Q-loop/lid; other site
399742003322	ABC transporter signature motif; other site
399742003323	Walker B; other site
399742003324	D-loop; other site
399742003325	H-loop/switch region; other site
399742003326	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
399742003327	Nitrogen regulatory protein P-II; Region: P-II; smart00938
399742003328	ammonium transporter; Provisional; Region: PRK10666
399742003329	acyl-CoA thioesterase II; Provisional; Region: PRK10526
399742003330	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
399742003331	active site
399742003332	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
399742003333	catalytic triad [active]
399742003334	dimer interface [polypeptide binding]; other site
399742003335	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
399742003336	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
399742003337	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
399742003338	DNA binding site [nucleotide binding]
399742003339	active site
399742003340	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
399742003341	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742003342	Coenzyme A binding pocket [chemical binding]; other site
399742003343	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
399742003344	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742003345	DNA-binding site [nucleotide binding]; DNA binding site
399742003346	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742003347	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742003348	homodimer interface [polypeptide binding]; other site
399742003349	catalytic residue [active]
399742003350	Predicted membrane protein [Function unknown]; Region: COG2364
399742003351	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
399742003352	lac repressor; Reviewed; Region: lacI; PRK09526
399742003353	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742003354	DNA binding site [nucleotide binding]
399742003355	domain linker motif; other site
399742003356	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
399742003357	ligand binding site [chemical binding]; other site
399742003358	dimerization interface (open form) [polypeptide binding]; other site
399742003359	dimerization interface (closed form) [polypeptide binding]; other site
399742003360	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
399742003361	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
399742003362	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
399742003363	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
399742003364	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
399742003365	Protein of unknown function (DUF1428); Region: DUF1428; cl02319
399742003366	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
399742003367	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
399742003368	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742003369	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
399742003370	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742003371	DNA-binding site [nucleotide binding]; DNA binding site
399742003372	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
399742003373	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
399742003374	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
399742003375	metal binding site [ion binding]; metal-binding site
399742003376	substrate binding pocket [chemical binding]; other site
399742003377	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742003378	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
399742003379	active site turn [active]
399742003380	phosphorylation site [posttranslational modification]
399742003381	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742003382	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
399742003383	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
399742003384	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
399742003385	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
399742003386	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
399742003387	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742003388	DNA-binding site [nucleotide binding]; DNA binding site
399742003389	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742003390	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742003391	homodimer interface [polypeptide binding]; other site
399742003392	catalytic residue [active]
399742003393	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
399742003394	maltose O-acetyltransferase; Provisional; Region: PRK10092
399742003395	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
399742003396	active site
399742003397	substrate binding site [chemical binding]; other site
399742003398	trimer interface [polypeptide binding]; other site
399742003399	CoA binding site [chemical binding]; other site
399742003400	gene expression modulator; Provisional; Region: PRK10945
399742003401	Hha toxicity attenuator; Provisional; Region: PRK10667
399742003402	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
399742003403	Protein export membrane protein; Region: SecD_SecF; cl14618
399742003404	Protein export membrane protein; Region: SecD_SecF; cl14618
399742003405	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
399742003406	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742003407	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742003408	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
399742003409	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742003410	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
399742003411	hypothetical protein; Provisional; Region: PRK11281
399742003412	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
399742003413	Mechanosensitive ion channel; Region: MS_channel; pfam00924
399742003414	Protein of unknown function (DUF2496); Region: DUF2496; pfam10689
399742003415	primosomal replication protein N''; Provisional; Region: PRK10093
399742003416	hypothetical protein; Provisional; Region: PRK10527
399742003417	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742003418	active site
399742003419	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
399742003420	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742003421	Walker A motif; other site
399742003422	ATP binding site [chemical binding]; other site
399742003423	Walker B motif; other site
399742003424	DNA polymerase III subunit delta'; Validated; Region: PRK08485
399742003425	arginine finger; other site
399742003426	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
399742003427	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
399742003428	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
399742003429	hypothetical protein; Validated; Region: PRK00153
399742003430	recombination protein RecR; Reviewed; Region: recR; PRK00076
399742003431	RecR protein; Region: RecR; pfam02132
399742003432	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
399742003433	putative active site [active]
399742003434	putative metal-binding site [ion binding]; other site
399742003435	tetramer interface [polypeptide binding]; other site
399742003436	heat shock protein 90; Provisional; Region: PRK05218
399742003437	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742003438	ATP binding site [chemical binding]; other site
399742003439	Mg2+ binding site [ion binding]; other site
399742003440	G-X-G motif; other site
399742003441	adenylate kinase; Reviewed; Region: adk; PRK00279
399742003442	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
399742003443	AMP-binding site [chemical binding]; other site
399742003444	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
399742003445	ferrochelatase; Reviewed; Region: hemH; PRK00035
399742003446	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
399742003447	C-terminal domain interface [polypeptide binding]; other site
399742003448	active site
399742003449	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
399742003450	active site
399742003451	N-terminal domain interface [polypeptide binding]; other site
399742003452	inosine/guanosine kinase; Provisional; Region: PRK15074
399742003453	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
399742003454	putative cation:proton antiport protein; Provisional; Region: PRK10669
399742003455	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
399742003456	TrkA-N domain; Region: TrkA_N; pfam02254
399742003457	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003458	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742003459	putative substrate translocation pore; other site
399742003460	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003461	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
399742003462	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
399742003463	active site
399742003464	metal binding site [ion binding]; metal-binding site
399742003465	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
399742003466	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
399742003467	putative deacylase active site [active]
399742003468	TraB family; Region: TraB; cl12050
399742003469	copper exporting ATPase; Provisional; Region: copA; PRK10671
399742003470	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
399742003471	metal-binding site [ion binding]
399742003472	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
399742003473	metal-binding site [ion binding]
399742003474	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
399742003475	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742003476	motif II; other site
399742003477	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
399742003478	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
399742003479	DNA binding residues [nucleotide binding]
399742003480	dimer interface [polypeptide binding]; other site
399742003481	copper binding site [ion binding]; other site
399742003482	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
399742003483	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
399742003484	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
399742003485	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
399742003486	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
399742003487	oxidoreductase; Provisional; Region: PRK08017
399742003488	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
399742003489	NADP binding site [chemical binding]; other site
399742003490	active site
399742003491	steroid binding site; other site
399742003492	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
399742003493	active site
399742003494	catalytic triad [active]
399742003495	oxyanion hole [active]
399742003496	switch loop; other site
399742003497	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
399742003498	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
399742003499	Walker A/P-loop; other site
399742003500	ATP binding site [chemical binding]; other site
399742003501	Q-loop/lid; other site
399742003502	ABC transporter signature motif; other site
399742003503	Walker B; other site
399742003504	D-loop; other site
399742003505	H-loop/switch region; other site
399742003506	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
399742003507	FtsX-like permease family; Region: FtsX; pfam02687
399742003508	FtsX-like permease family; Region: FtsX; pfam02687
399742003509	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742003510	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
399742003511	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
399742003512	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
399742003513	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
399742003514	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
399742003515	Walker A/P-loop; other site
399742003516	ATP binding site [chemical binding]; other site
399742003517	Q-loop/lid; other site
399742003518	ABC transporter signature motif; other site
399742003519	Walker B; other site
399742003520	D-loop; other site
399742003521	H-loop/switch region; other site
399742003522	NIL domain; Region: NIL; pfam09383
399742003523	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742003524	dimer interface [polypeptide binding]; other site
399742003525	conserved gate region; other site
399742003526	ABC-ATPase subunit interface; other site
399742003527	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
399742003528	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
399742003529	active site residue [active]
399742003530	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
399742003531	ATP-grasp domain; Region: ATP-grasp; pfam02222
399742003532	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
399742003533	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
399742003534	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
399742003535	putative active site [active]
399742003536	putative metal binding site [ion binding]; other site
399742003537	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
399742003538	substrate binding site [chemical binding]; other site
399742003539	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
399742003540	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
399742003541	active site
399742003542	HIGH motif; other site
399742003543	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
399742003544	KMSKS motif; other site
399742003545	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
399742003546	tRNA binding surface [nucleotide binding]; other site
399742003547	anticodon binding site; other site
399742003548	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
399742003549	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
399742003550	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
399742003551	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742003552	DNA binding site [nucleotide binding]
399742003553	domain linker motif; other site
399742003554	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
399742003555	putative dimerization interface [polypeptide binding]; other site
399742003556	putative ligand binding site [chemical binding]; other site
399742003557	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
399742003558	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742003559	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742003560	active site turn [active]
399742003561	phosphorylation site [posttranslational modification]
399742003562	ribosome-associated protein; Provisional; Region: PRK11507
399742003563	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
399742003564	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
399742003565	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
399742003566	homodimer interface [polypeptide binding]; other site
399742003567	NADP binding site [chemical binding]; other site
399742003568	substrate binding site [chemical binding]; other site
399742003569	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
399742003570	fimbrial protein FimI; Provisional; Region: PRK15200
399742003571	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
399742003572	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
399742003573	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
399742003574	outer membrane usher protein FimD; Provisional; Region: PRK15198
399742003575	PapC N-terminal domain; Region: PapC_N; pfam13954
399742003576	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
399742003577	PapC C-terminal domain; Region: PapC_C; pfam13953
399742003578	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
399742003579	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
399742003580	transcriptional regulator FimZ; Provisional; Region: PRK09935
399742003581	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742003582	active site
399742003583	phosphorylation site [posttranslational modification]
399742003584	intermolecular recognition site; other site
399742003585	dimerization interface [polypeptide binding]; other site
399742003586	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742003587	DNA binding residues [nucleotide binding]
399742003588	dimerization interface [polypeptide binding]; other site
399742003589	EAL domain; Region: EAL; pfam00563
399742003590	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
399742003591	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
399742003592	Int/Topo IB signature motif; other site
399742003593	Protein of unknown function (DUF2591); Region: DUF2591; pfam10765
399742003594	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
399742003595	RecT family; Region: RecT; pfam03837
399742003596	Viral hemorrhagic septicemia virus non-virion protein; Region: Novirhabdo_Nv; pfam05554
399742003597	Predicted transcriptional regulator [Transcription]; Region: COG2932
399742003598	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742003599	Catalytic site [active]
399742003600	Bacteriophage CII protein; Region: Phage_CII; pfam05269
399742003601	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
399742003602	Replication protein P; Region: Phage_lambda_P; pfam06992
399742003603	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
399742003604	Methyltransferase domain; Region: Methyltransf_25; pfam13649
399742003605	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
399742003606	active site
399742003607	hypothetical protein; Provisional; Region: PRK09741
399742003608	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
399742003609	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
399742003610	Acetokinase family; Region: Acetate_kinase; cl17229
399742003611	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
399742003612	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
399742003613	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
399742003614	large terminase protein; Provisional; Region: 17; PHA02533
399742003615	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
399742003616	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
399742003617	nudix motif; other site
399742003618	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
399742003619	virion protein; Provisional; Region: V; PHA02564
399742003620	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
399742003621	CobD/Cbib protein; Region: CobD_Cbib; cl00561
399742003622	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
399742003623	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
399742003624	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
399742003625	active site
399742003626	catalytic triad [active]
399742003627	oxyanion hole [active]
399742003628	ORF6N domain; Region: ORF6N; pfam10543
399742003629	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742003630	Catalytic site [active]
399742003631	hypothetical protein; Provisional; Region: PRK09929
399742003632	PQQ-like domain; Region: PQQ_2; pfam13360
399742003633	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
399742003634	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
399742003635	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742003636	N-terminal plug; other site
399742003637	ligand-binding site [chemical binding]; other site
399742003638	phenylalanine transporter; Provisional; Region: PRK10249
399742003639	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
399742003640	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003641	putative substrate translocation pore; other site
399742003642	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
399742003643	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
399742003644	Metal-binding active site; metal-binding site
399742003645	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
399742003646	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
399742003647	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
399742003648	NAD(P) binding site [chemical binding]; other site
399742003649	shikimate binding site; other site
399742003650	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
399742003651	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742003652	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742003653	DNA binding site [nucleotide binding]
399742003654	domain linker motif; other site
399742003655	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
399742003656	dimerization interface [polypeptide binding]; other site
399742003657	ligand binding site [chemical binding]; other site
399742003658	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
399742003659	Mechanosensitive ion channel; Region: MS_channel; pfam00924
399742003660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003661	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742003662	putative substrate translocation pore; other site
399742003663	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003664	Helix-turn-helix domain; Region: HTH_31; pfam13560
399742003665	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
399742003666	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742003667	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
399742003668	outer membrane usher protein; Provisional; Region: PRK15193
399742003669	PapC N-terminal domain; Region: PapC_N; pfam13954
399742003670	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
399742003671	PapC C-terminal domain; Region: PapC_C; pfam13953
399742003672	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742003673	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
399742003674	dimer interface [polypeptide binding]; other site
399742003675	FMN binding site [chemical binding]; other site
399742003676	hypothetical protein; Provisional; Region: PRK10250
399742003677	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742003678	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742003679	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
399742003680	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
399742003681	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
399742003682	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742003683	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
399742003684	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742003685	N-terminal plug; other site
399742003686	ligand-binding site [chemical binding]; other site
399742003687	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
399742003688	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
399742003689	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
399742003690	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
399742003691	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
399742003692	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
399742003693	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
399742003694	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
399742003695	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742003696	motif II; other site
399742003697	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
399742003698	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
399742003699	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742003700	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742003701	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
399742003702	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
399742003703	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
399742003704	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742003705	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742003706	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742003707	putative effector binding pocket; other site
399742003708	dimerization interface [polypeptide binding]; other site
399742003709	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742003710	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003711	putative substrate translocation pore; other site
399742003712	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003713	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
399742003714	phage resistance protein; Provisional; Region: PRK10551
399742003715	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
399742003716	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742003717	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
399742003718	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003719	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742003720	putative substrate translocation pore; other site
399742003721	Protein of unknown function, DUF606; Region: DUF606; pfam04657
399742003722	Protein of unknown function, DUF606; Region: DUF606; pfam04657
399742003723	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742003724	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742003725	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742003726	putative effector binding pocket; other site
399742003727	dimerization interface [polypeptide binding]; other site
399742003728	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
399742003729	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
399742003730	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
399742003731	active site
399742003732	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742003733	DNA-binding site [nucleotide binding]; DNA binding site
399742003734	RNA-binding motif; other site
399742003735	putative outer membrane receptor; Provisional; Region: PRK13513
399742003736	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742003737	N-terminal plug; other site
399742003738	ligand-binding site [chemical binding]; other site
399742003739	Uncharacterized conserved protein [Function unknown]; Region: COG3391
399742003740	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
399742003741	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
399742003742	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742003743	Walker A/P-loop; other site
399742003744	ATP binding site [chemical binding]; other site
399742003745	Q-loop/lid; other site
399742003746	ABC transporter signature motif; other site
399742003747	Walker B; other site
399742003748	D-loop; other site
399742003749	H-loop/switch region; other site
399742003750	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
399742003751	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742003752	Walker A/P-loop; other site
399742003753	ATP binding site [chemical binding]; other site
399742003754	Q-loop/lid; other site
399742003755	ABC transporter signature motif; other site
399742003756	Walker B; other site
399742003757	D-loop; other site
399742003758	H-loop/switch region; other site
399742003759	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
399742003760	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742003761	dimer interface [polypeptide binding]; other site
399742003762	conserved gate region; other site
399742003763	ABC-ATPase subunit interface; other site
399742003764	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
399742003765	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742003766	dimer interface [polypeptide binding]; other site
399742003767	conserved gate region; other site
399742003768	putative PBP binding loops; other site
399742003769	ABC-ATPase subunit interface; other site
399742003770	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742003771	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
399742003772	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
399742003773	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
399742003774	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
399742003775	Sel1-like repeats; Region: SEL1; smart00671
399742003776	Sel1-like repeats; Region: SEL1; smart00671
399742003777	Sel1-like repeats; Region: SEL1; smart00671
399742003778	Sel1-like repeats; Region: SEL1; smart00671
399742003779	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
399742003780	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742003781	DNA-binding site [nucleotide binding]; DNA binding site
399742003782	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742003783	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742003784	homodimer interface [polypeptide binding]; other site
399742003785	catalytic residue [active]
399742003786	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
399742003787	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742003788	Coenzyme A binding pocket [chemical binding]; other site
399742003789	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
399742003790	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
399742003791	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
399742003792	metal binding site [ion binding]; metal-binding site
399742003793	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
399742003794	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
399742003795	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
399742003796	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742003797	ABC-ATPase subunit  interface; other site
399742003798	dimer interface [polypeptide binding]; other site
399742003799	putative PBP binding regions; other site
399742003800	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
399742003801	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742003802	ABC-ATPase subunit  interface; other site
399742003803	dimer interface [polypeptide binding]; other site
399742003804	putative PBP binding regions; other site
399742003805	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
399742003806	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
399742003807	outer membrane receptor FepA; Provisional; Region: PRK13524
399742003808	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742003809	N-terminal plug; other site
399742003810	ligand-binding site [chemical binding]; other site
399742003811	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
399742003812	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
399742003813	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
399742003814	MbtH-like protein; Region: MbtH; cl01279
399742003815	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
399742003816	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
399742003817	acyl-activating enzyme (AAE) consensus motif; other site
399742003818	AMP binding site [chemical binding]; other site
399742003819	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
399742003820	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
399742003821	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742003822	Walker A/P-loop; other site
399742003823	ATP binding site [chemical binding]; other site
399742003824	Q-loop/lid; other site
399742003825	ABC transporter signature motif; other site
399742003826	Walker B; other site
399742003827	D-loop; other site
399742003828	H-loop/switch region; other site
399742003829	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
399742003830	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742003831	ABC-ATPase subunit  interface; other site
399742003832	dimer interface [polypeptide binding]; other site
399742003833	putative PBP binding regions; other site
399742003834	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
399742003835	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742003836	ABC-ATPase subunit  interface; other site
399742003837	dimer interface [polypeptide binding]; other site
399742003838	putative PBP binding regions; other site
399742003839	enterobactin exporter EntS; Provisional; Region: PRK10489
399742003840	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742003841	putative substrate translocation pore; other site
399742003842	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
399742003843	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
399742003844	intersubunit interface [polypeptide binding]; other site
399742003845	isochorismate synthase EntC; Provisional; Region: PRK15016
399742003846	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
399742003847	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
399742003848	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
399742003849	acyl-activating enzyme (AAE) consensus motif; other site
399742003850	active site
399742003851	AMP binding site [chemical binding]; other site
399742003852	substrate binding site [chemical binding]; other site
399742003853	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
399742003854	hydrophobic substrate binding pocket; other site
399742003855	Isochorismatase family; Region: Isochorismatase; pfam00857
399742003856	active site
399742003857	conserved cis-peptide bond; other site
399742003858	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
399742003859	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
399742003860	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
399742003861	putative NAD(P) binding site [chemical binding]; other site
399742003862	active site
399742003863	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
399742003864	CoenzymeA binding site [chemical binding]; other site
399742003865	subunit interaction site [polypeptide binding]; other site
399742003866	PHB binding site; other site
399742003867	carbon starvation protein A; Provisional; Region: PRK15015
399742003868	Carbon starvation protein CstA; Region: CstA; pfam02554
399742003869	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
399742003870	Uncharacterized small protein [Function unknown]; Region: COG2879
399742003871	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
399742003872	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742003873	salt bridge; other site
399742003874	non-specific DNA binding site [nucleotide binding]; other site
399742003875	sequence-specific DNA binding site [nucleotide binding]; other site
399742003876	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
399742003877	classical (c) SDRs; Region: SDR_c; cd05233
399742003878	NAD(P) binding site [chemical binding]; other site
399742003879	active site
399742003880	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
399742003881	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
399742003882	putative active site [active]
399742003883	metal binding site [ion binding]; metal-binding site
399742003884	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
399742003885	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742003886	Walker A/P-loop; other site
399742003887	ATP binding site [chemical binding]; other site
399742003888	Q-loop/lid; other site
399742003889	ABC transporter signature motif; other site
399742003890	Walker B; other site
399742003891	D-loop; other site
399742003892	H-loop/switch region; other site
399742003893	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742003894	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742003895	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742003896	TM-ABC transporter signature motif; other site
399742003897	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
399742003898	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
399742003899	putative ligand binding site [chemical binding]; other site
399742003900	Uncharacterized conserved protein [Function unknown]; Region: COG5276
399742003901	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
399742003902	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
399742003903	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
399742003904	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
399742003905	Cupin domain; Region: Cupin_2; cl17218
399742003906	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
399742003907	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742003908	motif II; other site
399742003909	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
399742003910	intersubunit interface [polypeptide binding]; other site
399742003911	active site
399742003912	Zn2+ binding site [ion binding]; other site
399742003913	methionine aminotransferase; Validated; Region: PRK09082
399742003914	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742003915	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742003916	homodimer interface [polypeptide binding]; other site
399742003917	catalytic residue [active]
399742003918	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
399742003919	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
399742003920	dimer interface [polypeptide binding]; other site
399742003921	decamer (pentamer of dimers) interface [polypeptide binding]; other site
399742003922	catalytic triad [active]
399742003923	peroxidatic and resolving cysteines [active]
399742003924	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
399742003925	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
399742003926	catalytic residue [active]
399742003927	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
399742003928	catalytic residues [active]
399742003929	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
399742003930	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742003931	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742003932	Ligand Binding Site [chemical binding]; other site
399742003933	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
399742003934	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
399742003935	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
399742003936	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
399742003937	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742003938	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
399742003939	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
399742003940	B1 nucleotide binding pocket [chemical binding]; other site
399742003941	B2 nucleotide binding pocket [chemical binding]; other site
399742003942	CAS motifs; other site
399742003943	active site
399742003944	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
399742003945	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
399742003946	Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604
399742003947	Outer membrane efflux protein; Region: OEP; pfam02321
399742003948	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
399742003949	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
399742003950	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742003951	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
399742003952	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
399742003953	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742003954	DNA-binding site [nucleotide binding]; DNA binding site
399742003955	RNA-binding motif; other site
399742003956	chromosome condensation membrane protein; Provisional; Region: PRK14196
399742003957	Predicted amidohydrolase [General function prediction only]; Region: COG0388
399742003958	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
399742003959	active site
399742003960	catalytic triad [active]
399742003961	dimer interface [polypeptide binding]; other site
399742003962	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
399742003963	lipoyl synthase; Provisional; Region: PRK05481
399742003964	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742003965	FeS/SAM binding site; other site
399742003966	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
399742003967	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742003968	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
399742003969	substrate binding pocket [chemical binding]; other site
399742003970	dimerization interface [polypeptide binding]; other site
399742003971	lipoate-protein ligase B; Provisional; Region: PRK14342
399742003972	hypothetical protein; Provisional; Region: PRK04998
399742003973	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
399742003974	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
399742003975	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
399742003976	rare lipoprotein A; Provisional; Region: PRK10672
399742003977	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
399742003978	cell wall shape-determining protein; Provisional; Region: PRK10794
399742003979	penicillin-binding protein 2; Provisional; Region: PRK10795
399742003980	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
399742003981	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
399742003982	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
399742003983	ribosome-associated protein; Provisional; Region: PRK11538
399742003984	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
399742003985	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
399742003986	active site
399742003987	(T/H)XGH motif; other site
399742003988	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
399742003989	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
399742003990	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
399742003991	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
399742003992	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
399742003993	HIGH motif; other site
399742003994	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
399742003995	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
399742003996	active site
399742003997	KMSKS motif; other site
399742003998	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
399742003999	tRNA binding surface [nucleotide binding]; other site
399742004000	hypothetical protein; Provisional; Region: PRK11032
399742004001	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
399742004002	active site
399742004003	tetramer interface [polypeptide binding]; other site
399742004004	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
399742004005	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
399742004006	Walker A/P-loop; other site
399742004007	ATP binding site [chemical binding]; other site
399742004008	Q-loop/lid; other site
399742004009	ABC transporter signature motif; other site
399742004010	Walker B; other site
399742004011	D-loop; other site
399742004012	H-loop/switch region; other site
399742004013	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742004014	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004015	dimer interface [polypeptide binding]; other site
399742004016	conserved gate region; other site
399742004017	putative PBP binding loops; other site
399742004018	ABC-ATPase subunit interface; other site
399742004019	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742004020	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004021	dimer interface [polypeptide binding]; other site
399742004022	conserved gate region; other site
399742004023	putative PBP binding loops; other site
399742004024	ABC-ATPase subunit interface; other site
399742004025	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
399742004026	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742004027	substrate binding pocket [chemical binding]; other site
399742004028	membrane-bound complex binding site; other site
399742004029	hinge residues; other site
399742004030	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
399742004031	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
399742004032	putative active site [active]
399742004033	catalytic triad [active]
399742004034	putative dimer interface [polypeptide binding]; other site
399742004035	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
399742004036	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
399742004037	Transporter associated domain; Region: CorC_HlyC; smart01091
399742004038	metal-binding heat shock protein; Provisional; Region: PRK00016
399742004039	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
399742004040	PhoH-like protein; Region: PhoH; pfam02562
399742004041	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
399742004042	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
399742004043	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742004044	FeS/SAM binding site; other site
399742004045	TRAM domain; Region: TRAM; pfam01938
399742004046	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
399742004047	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
399742004048	asparagine synthetase B; Provisional; Region: asnB; PRK09431
399742004049	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
399742004050	active site
399742004051	dimer interface [polypeptide binding]; other site
399742004052	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
399742004053	Ligand Binding Site [chemical binding]; other site
399742004054	Molecular Tunnel; other site
399742004055	UMP phosphatase; Provisional; Region: PRK10444
399742004056	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004057	active site
399742004058	motif I; other site
399742004059	motif II; other site
399742004060	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004061	MarR family; Region: MarR; pfam01047
399742004062	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
399742004063	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742004064	nucleotide binding site [chemical binding]; other site
399742004065	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
399742004066	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
399742004067	active site
399742004068	dimer interface [polypeptide binding]; other site
399742004069	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
399742004070	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
399742004071	active site
399742004072	trimer interface [polypeptide binding]; other site
399742004073	allosteric site; other site
399742004074	active site lid [active]
399742004075	hexamer (dimer of trimers) interface [polypeptide binding]; other site
399742004076	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
399742004077	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742004078	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742004079	active site turn [active]
399742004080	phosphorylation site [posttranslational modification]
399742004081	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
399742004082	HPr interaction site; other site
399742004083	glycerol kinase (GK) interaction site [polypeptide binding]; other site
399742004084	active site
399742004085	phosphorylation site [posttranslational modification]
399742004086	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
399742004087	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
399742004088	active site
399742004089	HIGH motif; other site
399742004090	nucleotide binding site [chemical binding]; other site
399742004091	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
399742004092	KMSKS motif; other site
399742004093	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
399742004094	outer membrane porin, OprD family; Region: OprD; pfam03573
399742004095	YbfN-like lipoprotein; Region: YbfN; pfam13982
399742004096	ferric uptake regulator; Provisional; Region: fur; PRK09462
399742004097	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
399742004098	metal binding site 2 [ion binding]; metal-binding site
399742004099	putative DNA binding helix; other site
399742004100	metal binding site 1 [ion binding]; metal-binding site
399742004101	dimer interface [polypeptide binding]; other site
399742004102	structural Zn2+ binding site [ion binding]; other site
399742004103	flavodoxin FldA; Validated; Region: PRK09267
399742004104	LexA regulated protein; Provisional; Region: PRK11675
399742004105	acyl-CoA esterase; Provisional; Region: PRK10673
399742004106	PGAP1-like protein; Region: PGAP1; pfam07819
399742004107	replication initiation regulator SeqA; Provisional; Region: PRK11187
399742004108	phosphoglucomutase; Validated; Region: PRK07564
399742004109	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
399742004110	active site
399742004111	substrate binding site [chemical binding]; other site
399742004112	metal binding site [ion binding]; metal-binding site
399742004113	putrescine transporter; Provisional; Region: potE; PRK10655
399742004114	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
399742004115	ornithine decarboxylase; Provisional; Region: PRK13578
399742004116	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
399742004117	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
399742004118	homodimer interface [polypeptide binding]; other site
399742004119	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742004120	catalytic residue [active]
399742004121	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
399742004122	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
399742004123	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742004124	active site
399742004125	phosphorylation site [posttranslational modification]
399742004126	intermolecular recognition site; other site
399742004127	dimerization interface [polypeptide binding]; other site
399742004128	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742004129	DNA binding site [nucleotide binding]
399742004130	sensor protein KdpD; Provisional; Region: PRK10490
399742004131	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
399742004132	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
399742004133	Ligand Binding Site [chemical binding]; other site
399742004134	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
399742004135	GAF domain; Region: GAF_3; pfam13492
399742004136	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742004137	dimer interface [polypeptide binding]; other site
399742004138	phosphorylation site [posttranslational modification]
399742004139	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742004140	ATP binding site [chemical binding]; other site
399742004141	Mg2+ binding site [ion binding]; other site
399742004142	G-X-G motif; other site
399742004143	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
399742004144	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
399742004145	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
399742004146	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
399742004147	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
399742004148	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
399742004149	DNA photolyase; Region: DNA_photolyase; pfam00875
399742004150	Uncharacterized conserved protein [Function unknown]; Region: COG0327
399742004151	metal-binding protein; Provisional; Region: PRK10799
399742004152	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
399742004153	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
399742004154	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
399742004155	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
399742004156	putative active site [active]
399742004157	Protein of unknown function (DUF969); Region: DUF969; pfam06149
399742004158	Predicted membrane protein [Function unknown]; Region: COG3817
399742004159	Protein of unknown function (DUF979); Region: DUF979; pfam06166
399742004160	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
399742004161	putative substrate binding pocket [chemical binding]; other site
399742004162	AC domain interface; other site
399742004163	catalytic triad [active]
399742004164	AB domain interface; other site
399742004165	interchain disulfide; other site
399742004166	endonuclease VIII; Provisional; Region: PRK10445
399742004167	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
399742004168	DNA binding site [nucleotide binding]
399742004169	catalytic residue [active]
399742004170	putative catalytic residues [active]
399742004171	H2TH interface [polypeptide binding]; other site
399742004172	intercalation triad [nucleotide binding]; other site
399742004173	substrate specificity determining residue; other site
399742004174	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
399742004175	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
399742004176	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
399742004177	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
399742004178	dimer interface [polypeptide binding]; other site
399742004179	active site
399742004180	citrylCoA binding site [chemical binding]; other site
399742004181	NADH binding [chemical binding]; other site
399742004182	cationic pore residues; other site
399742004183	oxalacetate/citrate binding site [chemical binding]; other site
399742004184	coenzyme A binding site [chemical binding]; other site
399742004185	catalytic triad [active]
399742004186	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
399742004187	Iron-sulfur protein interface; other site
399742004188	proximal quinone binding site [chemical binding]; other site
399742004189	SdhD (CybS) interface [polypeptide binding]; other site
399742004190	proximal heme binding site [chemical binding]; other site
399742004191	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
399742004192	SdhC subunit interface [polypeptide binding]; other site
399742004193	proximal heme binding site [chemical binding]; other site
399742004194	cardiolipin binding site; other site
399742004195	Iron-sulfur protein interface; other site
399742004196	proximal quinone binding site [chemical binding]; other site
399742004197	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
399742004198	L-aspartate oxidase; Provisional; Region: PRK06175
399742004199	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
399742004200	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
399742004201	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
399742004202	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
399742004203	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
399742004204	TPP-binding site [chemical binding]; other site
399742004205	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
399742004206	dimer interface [polypeptide binding]; other site
399742004207	PYR/PP interface [polypeptide binding]; other site
399742004208	TPP binding site [chemical binding]; other site
399742004209	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
399742004210	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
399742004211	E3 interaction surface; other site
399742004212	lipoyl attachment site [posttranslational modification]; other site
399742004213	e3 binding domain; Region: E3_binding; pfam02817
399742004214	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
399742004215	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
399742004216	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
399742004217	CoA-ligase; Region: Ligase_CoA; pfam00549
399742004218	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
399742004219	CoA binding domain; Region: CoA_binding; smart00881
399742004220	CoA-ligase; Region: Ligase_CoA; pfam00549
399742004221	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
399742004222	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
399742004223	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
399742004224	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
399742004225	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
399742004226	hypothetical protein; Provisional; Region: PRK10588
399742004227	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
399742004228	active site
399742004229	colicin uptake protein TolQ; Provisional; Region: PRK10801
399742004230	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
399742004231	colicin uptake protein TolR; Provisional; Region: PRK11024
399742004232	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
399742004233	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
399742004234	TolA C-terminal; Region: TolA; pfam06519
399742004235	translocation protein TolB; Provisional; Region: tolB; PRK03629
399742004236	TolB amino-terminal domain; Region: TolB_N; pfam04052
399742004237	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
399742004238	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
399742004239	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
399742004240	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
399742004241	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
399742004242	ligand binding site [chemical binding]; other site
399742004243	tol-pal system protein YbgF; Provisional; Region: PRK10803
399742004244	Tetratricopeptide repeat; Region: TPR_6; pfam13174
399742004245	Tetratricopeptide repeat; Region: TPR_6; pfam13174
399742004246	quinolinate synthetase; Provisional; Region: PRK09375
399742004247	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
399742004248	zinc transporter ZitB; Provisional; Region: PRK03557
399742004249	YbgS-like protein; Region: YbgS; pfam13985
399742004250	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
399742004251	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
399742004252	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
399742004253	catalytic core [active]
399742004254	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
399742004255	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
399742004256	active site
399742004257	catalytic residues [active]
399742004258	galactokinase; Provisional; Region: PRK05101
399742004259	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
399742004260	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
399742004261	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
399742004262	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
399742004263	dimer interface [polypeptide binding]; other site
399742004264	active site
399742004265	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
399742004266	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
399742004267	NAD binding site [chemical binding]; other site
399742004268	homodimer interface [polypeptide binding]; other site
399742004269	active site
399742004270	substrate binding site [chemical binding]; other site
399742004271	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
399742004272	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004273	Walker A/P-loop; other site
399742004274	ATP binding site [chemical binding]; other site
399742004275	Q-loop/lid; other site
399742004276	ABC transporter signature motif; other site
399742004277	Walker B; other site
399742004278	D-loop; other site
399742004279	H-loop/switch region; other site
399742004280	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004281	Walker A/P-loop; other site
399742004282	ATP binding site [chemical binding]; other site
399742004283	Q-loop/lid; other site
399742004284	ABC transporter signature motif; other site
399742004285	Walker B; other site
399742004286	D-loop; other site
399742004287	H-loop/switch region; other site
399742004288	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
399742004289	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
399742004290	molybdenum-pterin binding domain; Region: Mop; TIGR00638
399742004291	TOBE domain; Region: TOBE; pfam03459
399742004292	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
399742004293	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
399742004294	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742004295	membrane-bound complex binding site; other site
399742004296	hinge residues; other site
399742004297	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
399742004298	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004299	dimer interface [polypeptide binding]; other site
399742004300	conserved gate region; other site
399742004301	putative PBP binding loops; other site
399742004302	ABC-ATPase subunit interface; other site
399742004303	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
399742004304	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004305	Walker A/P-loop; other site
399742004306	ATP binding site [chemical binding]; other site
399742004307	Q-loop/lid; other site
399742004308	ABC transporter signature motif; other site
399742004309	Walker B; other site
399742004310	D-loop; other site
399742004311	H-loop/switch region; other site
399742004312	molybdenum-pterin binding domain; Region: Mop; TIGR00638
399742004313	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
399742004314	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004315	active site
399742004316	motif I; other site
399742004317	motif II; other site
399742004318	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004319	6-phosphogluconolactonase; Provisional; Region: PRK11028
399742004320	acyl-CoA thioesterase; Provisional; Region: PRK10531
399742004321	putative pectinesterase; Region: PLN02432; cl01911
399742004322	imidazolonepropionase; Validated; Region: PRK09356
399742004323	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
399742004324	active site
399742004325	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
399742004326	putative active site [active]
399742004327	putative metal binding site [ion binding]; other site
399742004328	histidine utilization repressor; Provisional; Region: PRK14999
399742004329	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742004330	DNA-binding site [nucleotide binding]; DNA binding site
399742004331	UTRA domain; Region: UTRA; pfam07702
399742004332	urocanate hydratase; Provisional; Region: PRK05414
399742004333	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
399742004334	active sites [active]
399742004335	tetramer interface [polypeptide binding]; other site
399742004336	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
399742004337	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742004338	inhibitor-cofactor binding pocket; inhibition site
399742004339	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742004340	catalytic residue [active]
399742004341	biotin synthase; Provisional; Region: PRK15108
399742004342	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742004343	FeS/SAM binding site; other site
399742004344	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
399742004345	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
399742004346	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
399742004347	substrate-cofactor binding pocket; other site
399742004348	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742004349	catalytic residue [active]
399742004350	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
399742004351	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742004352	S-adenosylmethionine binding site [chemical binding]; other site
399742004353	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
399742004354	AAA domain; Region: AAA_26; pfam13500
399742004355	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
399742004356	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004357	Walker A/P-loop; other site
399742004358	ATP binding site [chemical binding]; other site
399742004359	Q-loop/lid; other site
399742004360	ABC transporter signature motif; other site
399742004361	Walker B; other site
399742004362	D-loop; other site
399742004363	H-loop/switch region; other site
399742004364	excinuclease ABC subunit B; Provisional; Region: PRK05298
399742004365	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742004366	ATP binding site [chemical binding]; other site
399742004367	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742004368	nucleotide binding region [chemical binding]; other site
399742004369	ATP-binding site [chemical binding]; other site
399742004370	Ultra-violet resistance protein B; Region: UvrB; pfam12344
399742004371	UvrB/uvrC motif; Region: UVR; pfam02151
399742004372	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
399742004373	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
399742004374	phosphate binding site [ion binding]; other site
399742004375	putative substrate binding pocket [chemical binding]; other site
399742004376	dimer interface [polypeptide binding]; other site
399742004377	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
399742004378	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742004379	FeS/SAM binding site; other site
399742004380	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
399742004381	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
399742004382	MPT binding site; other site
399742004383	trimer interface [polypeptide binding]; other site
399742004384	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
399742004385	trimer interface [polypeptide binding]; other site
399742004386	dimer interface [polypeptide binding]; other site
399742004387	putative active site [active]
399742004388	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
399742004389	MoaE interaction surface [polypeptide binding]; other site
399742004390	MoeB interaction surface [polypeptide binding]; other site
399742004391	thiocarboxylated glycine; other site
399742004392	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
399742004393	MoaE homodimer interface [polypeptide binding]; other site
399742004394	MoaD interaction [polypeptide binding]; other site
399742004395	active site residues [active]
399742004396	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
399742004397	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
399742004398	Predicted integral membrane protein [Function unknown]; Region: COG0392
399742004399	cardiolipin synthase 2; Provisional; Region: PRK11263
399742004400	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
399742004401	putative active site [active]
399742004402	catalytic site [active]
399742004403	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
399742004404	putative active site [active]
399742004405	catalytic site [active]
399742004406	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
399742004407	putative catalytic site [active]
399742004408	putative metal binding site [ion binding]; other site
399742004409	putative phosphate binding site [ion binding]; other site
399742004410	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
399742004411	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
399742004412	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
399742004413	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
399742004414	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
399742004415	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
399742004416	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
399742004417	Walker A/P-loop; other site
399742004418	ATP binding site [chemical binding]; other site
399742004419	Q-loop/lid; other site
399742004420	ABC transporter signature motif; other site
399742004421	Walker B; other site
399742004422	D-loop; other site
399742004423	H-loop/switch region; other site
399742004424	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
399742004425	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
399742004426	Walker A/P-loop; other site
399742004427	ATP binding site [chemical binding]; other site
399742004428	Q-loop/lid; other site
399742004429	ABC transporter signature motif; other site
399742004430	Walker B; other site
399742004431	D-loop; other site
399742004432	H-loop/switch region; other site
399742004433	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
399742004434	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742004435	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742004436	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
399742004437	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742004438	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
399742004439	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
399742004440	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
399742004441	ATP binding site [chemical binding]; other site
399742004442	Mg++ binding site [ion binding]; other site
399742004443	motif III; other site
399742004444	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742004445	nucleotide binding region [chemical binding]; other site
399742004446	ATP-binding site [chemical binding]; other site
399742004447	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
399742004448	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
399742004449	DEAD_2; Region: DEAD_2; pfam06733
399742004450	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
399742004451	glycosyl transferase family protein; Provisional; Region: PRK08136
399742004452	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
399742004453	hypothetical protein; Provisional; Region: PRK10259
399742004454	hypothetical protein; Provisional; Region: PRK11019
399742004455	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742004456	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
399742004457	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742004458	S-adenosylmethionine binding site [chemical binding]; other site
399742004459	putative mechanosensitive channel protein; Provisional; Region: PRK11465
399742004460	Mechanosensitive ion channel; Region: MS_channel; pfam00924
399742004461	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
399742004462	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
399742004463	Walker A/P-loop; other site
399742004464	ATP binding site [chemical binding]; other site
399742004465	Q-loop/lid; other site
399742004466	ABC transporter signature motif; other site
399742004467	Walker B; other site
399742004468	D-loop; other site
399742004469	H-loop/switch region; other site
399742004470	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742004471	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004472	dimer interface [polypeptide binding]; other site
399742004473	conserved gate region; other site
399742004474	putative PBP binding loops; other site
399742004475	ABC-ATPase subunit interface; other site
399742004476	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
399742004477	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742004478	substrate binding pocket [chemical binding]; other site
399742004479	membrane-bound complex binding site; other site
399742004480	hinge residues; other site
399742004481	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
399742004482	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
399742004483	dimerization interface [polypeptide binding]; other site
399742004484	DPS ferroxidase diiron center [ion binding]; other site
399742004485	ion pore; other site
399742004486	threonine and homoserine efflux system; Provisional; Region: PRK10532
399742004487	EamA-like transporter family; Region: EamA; pfam00892
399742004488	outer membrane protein X; Provisional; Region: ompX; PRK09408
399742004489	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
399742004490	Sulfatase; Region: Sulfatase; pfam00884
399742004491	manganese transport regulator MntR; Provisional; Region: PRK11050
399742004492	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
399742004493	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
399742004494	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
399742004495	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
399742004496	transmembrane helices; other site
399742004497	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742004498	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742004499	active site
399742004500	catalytic tetrad [active]
399742004501	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
399742004502	beta-galactosidase; Region: BGL; TIGR03356
399742004503	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
399742004504	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
399742004505	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
399742004506	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742004507	DNA-binding site [nucleotide binding]; DNA binding site
399742004508	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
399742004509	L,D-transpeptidase; Provisional; Region: PRK10260
399742004510	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
399742004511	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
399742004512	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742004513	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742004514	ABC transporter; Region: ABC_tran_2; pfam12848
399742004515	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742004516	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
399742004517	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
399742004518	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
399742004519	putative active site [active]
399742004520	putative catalytic site [active]
399742004521	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742004522	D-galactonate transporter; Region: 2A0114; TIGR00893
399742004523	putative substrate translocation pore; other site
399742004524	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742004525	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742004526	DNA binding site [nucleotide binding]
399742004527	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
399742004528	ligand binding site [chemical binding]; other site
399742004529	dimerization interface [polypeptide binding]; other site
399742004530	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
399742004531	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
399742004532	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004533	active site
399742004534	motif I; other site
399742004535	motif II; other site
399742004536	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004537	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
399742004538	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
399742004539	dimer interface [polypeptide binding]; other site
399742004540	active site
399742004541	glycine loop; other site
399742004542	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
399742004543	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742004544	FeS/SAM binding site; other site
399742004545	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
399742004546	active site
399742004547	intersubunit interactions; other site
399742004548	catalytic residue [active]
399742004549	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
399742004550	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
399742004551	ATP binding site [chemical binding]; other site
399742004552	substrate interface [chemical binding]; other site
399742004553	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
399742004554	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
399742004555	dimer interface [polypeptide binding]; other site
399742004556	putative functional site; other site
399742004557	putative MPT binding site; other site
399742004558	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
399742004559	catalytic nucleophile [active]
399742004560	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
399742004561	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742004562	Walker A/P-loop; other site
399742004563	ATP binding site [chemical binding]; other site
399742004564	Q-loop/lid; other site
399742004565	ABC transporter signature motif; other site
399742004566	Walker B; other site
399742004567	D-loop; other site
399742004568	H-loop/switch region; other site
399742004569	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
399742004570	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742004571	Walker A/P-loop; other site
399742004572	ATP binding site [chemical binding]; other site
399742004573	Q-loop/lid; other site
399742004574	ABC transporter signature motif; other site
399742004575	Walker B; other site
399742004576	D-loop; other site
399742004577	H-loop/switch region; other site
399742004578	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
399742004579	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
399742004580	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
399742004581	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
399742004582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004583	dimer interface [polypeptide binding]; other site
399742004584	conserved gate region; other site
399742004585	putative PBP binding loops; other site
399742004586	ABC-ATPase subunit interface; other site
399742004587	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
399742004588	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
399742004589	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004590	dimer interface [polypeptide binding]; other site
399742004591	conserved gate region; other site
399742004592	putative PBP binding loops; other site
399742004593	ABC-ATPase subunit interface; other site
399742004594	Biofilm formation protein (YliH/bssR); Region: YliH; pfam10799
399742004595	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
399742004596	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
399742004597	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
399742004598	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
399742004599	putative C-terminal domain interface [polypeptide binding]; other site
399742004600	putative GSH binding site (G-site) [chemical binding]; other site
399742004601	putative dimer interface [polypeptide binding]; other site
399742004602	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
399742004603	putative N-terminal domain interface [polypeptide binding]; other site
399742004604	putative dimer interface [polypeptide binding]; other site
399742004605	putative substrate binding pocket (H-site) [chemical binding]; other site
399742004606	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
399742004607	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
399742004608	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
399742004609	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
399742004610	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
399742004611	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
399742004612	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
399742004613	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
399742004614	active site
399742004615	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
399742004616	active site
399742004617	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
399742004618	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742004619	putative substrate translocation pore; other site
399742004620	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
399742004621	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004622	active site
399742004623	motif I; other site
399742004624	motif II; other site
399742004625	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742004626	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742004627	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742004628	putative substrate translocation pore; other site
399742004629	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
399742004630	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742004631	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
399742004632	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
399742004633	Acyltransferase family; Region: Acyl_transf_3; pfam01757
399742004634	integrase; Provisional; Region: int; PHA02601
399742004635	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
399742004636	active site
399742004637	DNA binding site [nucleotide binding]
399742004638	Int/Topo IB signature motif; other site
399742004639	Domain of unknown function (DUF4041); Region: DUF4041; pfam13250
399742004640	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
399742004641	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
399742004642	Helix-turn-helix domain; Region: HTH_17; cl17695
399742004643	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
399742004644	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
399742004645	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
399742004646	DksA-like zinc finger domain containing protein; Region: PHA00080
399742004647	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
399742004648	Active Sites [active]
399742004649	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
399742004650	TIGR04255 family protein; Region: sporadTIGR04255
399742004651	portal vertex protein; Provisional; Region: Q; PHA02536
399742004652	Phage portal protein; Region: Phage_portal; pfam04860
399742004653	terminase ATPase subunit; Provisional; Region: P; PHA02535
399742004654	Phage-related tail protein [Function unknown]; Region: COG5283
399742004655	Phage protein U [General function prediction only]; Region: COG3499
399742004656	tail protein; Provisional; Region: D; PHA02561
399742004657	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
399742004658	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
399742004659	This domain contains a conserved N-terminal (F/Y)RG motif. It is functionally uncharacterised; Region: FRG; smart00901
399742004660	putative transporter; Provisional; Region: PRK04972
399742004661	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
399742004662	TrkA-C domain; Region: TrkA_C; pfam02080
399742004663	TrkA-C domain; Region: TrkA_C; pfam02080
399742004664	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
399742004665	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
399742004666	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
399742004667	GSH binding site [chemical binding]; other site
399742004668	catalytic residues [active]
399742004669	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
399742004670	dimer interface [polypeptide binding]; other site
399742004671	FMN binding site [chemical binding]; other site
399742004672	NADPH bind site [chemical binding]; other site
399742004673	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
399742004674	RimK-like ATP-grasp domain; Region: RimK; pfam08443
399742004675	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
399742004676	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
399742004677	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
399742004678	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
399742004679	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004680	Walker A/P-loop; other site
399742004681	ATP binding site [chemical binding]; other site
399742004682	Q-loop/lid; other site
399742004683	ABC transporter signature motif; other site
399742004684	Walker B; other site
399742004685	D-loop; other site
399742004686	H-loop/switch region; other site
399742004687	TOBE domain; Region: TOBE_2; pfam08402
399742004688	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
399742004689	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004690	dimer interface [polypeptide binding]; other site
399742004691	conserved gate region; other site
399742004692	putative PBP binding loops; other site
399742004693	ABC-ATPase subunit interface; other site
399742004694	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
399742004695	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004696	dimer interface [polypeptide binding]; other site
399742004697	conserved gate region; other site
399742004698	putative PBP binding loops; other site
399742004699	ABC-ATPase subunit interface; other site
399742004700	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
399742004701	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
399742004702	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742004703	S-adenosylmethionine binding site [chemical binding]; other site
399742004704	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
399742004705	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742004706	active site
399742004707	phosphorylation site [posttranslational modification]
399742004708	intermolecular recognition site; other site
399742004709	dimerization interface [polypeptide binding]; other site
399742004710	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742004711	DNA binding site [nucleotide binding]
399742004712	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
399742004713	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742004714	dimer interface [polypeptide binding]; other site
399742004715	phosphorylation site [posttranslational modification]
399742004716	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742004717	ATP binding site [chemical binding]; other site
399742004718	Mg2+ binding site [ion binding]; other site
399742004719	G-X-G motif; other site
399742004720	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
399742004721	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742004722	substrate binding pocket [chemical binding]; other site
399742004723	membrane-bound complex binding site; other site
399742004724	hinge residues; other site
399742004725	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742004726	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004727	dimer interface [polypeptide binding]; other site
399742004728	conserved gate region; other site
399742004729	putative PBP binding loops; other site
399742004730	ABC-ATPase subunit interface; other site
399742004731	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742004732	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742004733	dimer interface [polypeptide binding]; other site
399742004734	conserved gate region; other site
399742004735	putative PBP binding loops; other site
399742004736	ABC-ATPase subunit interface; other site
399742004737	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
399742004738	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742004739	substrate binding pocket [chemical binding]; other site
399742004740	membrane-bound complex binding site; other site
399742004741	hinge residues; other site
399742004742	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
399742004743	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004744	Walker A/P-loop; other site
399742004745	ATP binding site [chemical binding]; other site
399742004746	Q-loop/lid; other site
399742004747	ABC transporter signature motif; other site
399742004748	Walker B; other site
399742004749	D-loop; other site
399742004750	H-loop/switch region; other site
399742004751	putative lipoprotein; Provisional; Region: PRK10533
399742004752	hypothetical protein; Provisional; Region: PRK02877
399742004753	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
399742004754	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
399742004755	amidase catalytic site [active]
399742004756	Zn binding residues [ion binding]; other site
399742004757	substrate binding site [chemical binding]; other site
399742004758	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
399742004759	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742004760	NAD(P) binding site [chemical binding]; other site
399742004761	active site
399742004762	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
399742004763	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
399742004764	putative NAD(P) binding site [chemical binding]; other site
399742004765	putative active site [active]
399742004766	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
399742004767	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
399742004768	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
399742004769	tetramer interface [polypeptide binding]; other site
399742004770	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742004771	catalytic residue [active]
399742004772	pyruvate dehydrogenase; Provisional; Region: PRK09124
399742004773	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
399742004774	PYR/PP interface [polypeptide binding]; other site
399742004775	dimer interface [polypeptide binding]; other site
399742004776	tetramer interface [polypeptide binding]; other site
399742004777	TPP binding site [chemical binding]; other site
399742004778	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
399742004779	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
399742004780	TPP-binding site [chemical binding]; other site
399742004781	Predicted membrane protein [Function unknown]; Region: COG2259
399742004782	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
399742004783	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
399742004784	FAD binding pocket [chemical binding]; other site
399742004785	FAD binding motif [chemical binding]; other site
399742004786	phosphate binding motif [ion binding]; other site
399742004787	beta-alpha-beta structure motif; other site
399742004788	NAD binding pocket [chemical binding]; other site
399742004789	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
399742004790	catalytic loop [active]
399742004791	iron binding site [ion binding]; other site
399742004792	hybrid cluster protein; Provisional; Region: PRK05290
399742004793	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
399742004794	ACS interaction site; other site
399742004795	CODH interaction site; other site
399742004796	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
399742004797	hybrid metal cluster; other site
399742004798	Predicted membrane protein [Function unknown]; Region: COG2431
399742004799	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
399742004800	amphipathic channel; other site
399742004801	Asn-Pro-Ala signature motifs; other site
399742004802	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
399742004803	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
399742004804	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
399742004805	putative active site [active]
399742004806	putative metal-binding site [ion binding]; other site
399742004807	Protein of unknown function (DUF535); Region: DUF535; pfam04393
399742004808	macrolide transporter subunit MacA; Provisional; Region: PRK11578
399742004809	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742004810	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742004811	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
399742004812	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
399742004813	Walker A/P-loop; other site
399742004814	ATP binding site [chemical binding]; other site
399742004815	Q-loop/lid; other site
399742004816	ABC transporter signature motif; other site
399742004817	Walker B; other site
399742004818	D-loop; other site
399742004819	H-loop/switch region; other site
399742004820	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
399742004821	FtsX-like permease family; Region: FtsX; pfam02687
399742004822	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742004823	DNA-binding site [nucleotide binding]; DNA binding site
399742004824	RNA-binding motif; other site
399742004825	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
399742004826	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
399742004827	Clp amino terminal domain; Region: Clp_N; pfam02861
399742004828	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742004829	Walker A motif; other site
399742004830	ATP binding site [chemical binding]; other site
399742004831	Walker B motif; other site
399742004832	arginine finger; other site
399742004833	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742004834	Walker A motif; other site
399742004835	ATP binding site [chemical binding]; other site
399742004836	Walker B motif; other site
399742004837	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
399742004838	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-F; cd09718
399742004839	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
399742004840	CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562
399742004841	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735
399742004842	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09736
399742004843	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737
399742004844	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09739
399742004845	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
399742004846	rRNA binding site [nucleotide binding]; other site
399742004847	predicted 30S ribosome binding site; other site
399742004848	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
399742004849	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
399742004850	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004851	Walker A/P-loop; other site
399742004852	ATP binding site [chemical binding]; other site
399742004853	Q-loop/lid; other site
399742004854	ABC transporter signature motif; other site
399742004855	Walker B; other site
399742004856	D-loop; other site
399742004857	H-loop/switch region; other site
399742004858	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
399742004859	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
399742004860	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742004861	Walker A/P-loop; other site
399742004862	ATP binding site [chemical binding]; other site
399742004863	Q-loop/lid; other site
399742004864	ABC transporter signature motif; other site
399742004865	Walker B; other site
399742004866	D-loop; other site
399742004867	H-loop/switch region; other site
399742004868	thioredoxin reductase; Provisional; Region: PRK10262
399742004869	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
399742004870	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742004871	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
399742004872	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742004873	putative DNA binding site [nucleotide binding]; other site
399742004874	putative Zn2+ binding site [ion binding]; other site
399742004875	AsnC family; Region: AsnC_trans_reg; pfam01037
399742004876	DNA translocase FtsK; Provisional; Region: PRK10263
399742004877	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
399742004878	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
399742004879	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
399742004880	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
399742004881	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
399742004882	recombination factor protein RarA; Reviewed; Region: PRK13342
399742004883	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742004884	Walker A motif; other site
399742004885	ATP binding site [chemical binding]; other site
399742004886	Walker B motif; other site
399742004887	arginine finger; other site
399742004888	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
399742004889	seryl-tRNA synthetase; Provisional; Region: PRK05431
399742004890	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
399742004891	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
399742004892	dimer interface [polypeptide binding]; other site
399742004893	active site
399742004894	motif 1; other site
399742004895	motif 2; other site
399742004896	motif 3; other site
399742004897	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
399742004898	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
399742004899	putative [Fe4-S4] binding site [ion binding]; other site
399742004900	putative molybdopterin cofactor binding site [chemical binding]; other site
399742004901	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
399742004902	putative molybdopterin cofactor binding site; other site
399742004903	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
399742004904	4Fe-4S binding domain; Region: Fer4; pfam00037
399742004905	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
399742004906	putative MFS family transporter protein; Provisional; Region: PRK03633
399742004907	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742004908	putative substrate translocation pore; other site
399742004909	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
399742004910	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742004911	FeS/SAM binding site; other site
399742004912	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
399742004913	Pyruvate formate lyase 1; Region: PFL1; cd01678
399742004914	coenzyme A binding site [chemical binding]; other site
399742004915	active site
399742004916	catalytic residues [active]
399742004917	glycine loop; other site
399742004918	formate transporter; Provisional; Region: PRK10805
399742004919	uncharacterized domain; Region: TIGR00702
399742004920	YcaO-like family; Region: YcaO; pfam02624
399742004921	Predicted membrane protein [Function unknown]; Region: COG2323
399742004922	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
399742004923	homodimer interface [polypeptide binding]; other site
399742004924	substrate-cofactor binding pocket; other site
399742004925	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742004926	catalytic residue [active]
399742004927	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
399742004928	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
399742004929	hinge; other site
399742004930	active site
399742004931	cytidylate kinase; Provisional; Region: cmk; PRK00023
399742004932	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
399742004933	CMP-binding site; other site
399742004934	The sites determining sugar specificity; other site
399742004935	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
399742004936	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
399742004937	RNA binding site [nucleotide binding]; other site
399742004938	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
399742004939	RNA binding site [nucleotide binding]; other site
399742004940	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
399742004941	RNA binding site [nucleotide binding]; other site
399742004942	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
399742004943	RNA binding site [nucleotide binding]; other site
399742004944	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
399742004945	RNA binding site [nucleotide binding]; other site
399742004946	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
399742004947	RNA binding site [nucleotide binding]; other site
399742004948	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
399742004949	IHF dimer interface [polypeptide binding]; other site
399742004950	IHF - DNA interface [nucleotide binding]; other site
399742004951	ComEC family competence protein; Provisional; Region: PRK11539
399742004952	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
399742004953	Competence protein; Region: Competence; pfam03772
399742004954	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
399742004955	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
399742004956	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
399742004957	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
399742004958	Walker A/P-loop; other site
399742004959	ATP binding site [chemical binding]; other site
399742004960	Q-loop/lid; other site
399742004961	ABC transporter signature motif; other site
399742004962	Walker B; other site
399742004963	D-loop; other site
399742004964	H-loop/switch region; other site
399742004965	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
399742004966	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
399742004967	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
399742004968	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
399742004969	Trm112p-like protein; Region: Trm112p; cl01066
399742004970	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
399742004971	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
399742004972	Ligand binding site; other site
399742004973	oligomer interface; other site
399742004974	hypothetical protein; Provisional; Region: PRK10593
399742004975	Uncharacterized conserved protein [Function unknown]; Region: COG1434
399742004976	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
399742004977	putative active site [active]
399742004978	Methyltransferase domain; Region: Methyltransf_23; pfam13489
399742004979	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742004980	S-adenosylmethionine binding site [chemical binding]; other site
399742004981	condesin subunit F; Provisional; Region: PRK05260
399742004982	condesin subunit E; Provisional; Region: PRK05256
399742004983	cell division protein MukB; Provisional; Region: mukB; PRK04863
399742004984	P-loop containing region of AAA domain; Region: AAA_29; cl17516
399742004985	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
399742004986	murein L,D-transpeptidase; Provisional; Region: PRK10594
399742004987	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
399742004988	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
399742004989	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
399742004990	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
399742004991	Peptidase M15; Region: Peptidase_M15_3; cl01194
399742004992	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
399742004993	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
399742004994	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742004995	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742004996	homodimer interface [polypeptide binding]; other site
399742004997	catalytic residue [active]
399742004998	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742004999	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
399742005000	trimer interface [polypeptide binding]; other site
399742005001	eyelet of channel; other site
399742005002	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
399742005003	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
399742005004	putative dimer interface [polypeptide binding]; other site
399742005005	putative anticodon binding site; other site
399742005006	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
399742005007	homodimer interface [polypeptide binding]; other site
399742005008	motif 1; other site
399742005009	motif 2; other site
399742005010	active site
399742005011	motif 3; other site
399742005012	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
399742005013	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
399742005014	active site
399742005015	aminopeptidase N; Provisional; Region: pepN; PRK14015
399742005016	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
399742005017	active site
399742005018	Zn binding site [ion binding]; other site
399742005019	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
399742005020	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
399742005021	Walker A/P-loop; other site
399742005022	ATP binding site [chemical binding]; other site
399742005023	Q-loop/lid; other site
399742005024	ABC transporter signature motif; other site
399742005025	Walker B; other site
399742005026	D-loop; other site
399742005027	H-loop/switch region; other site
399742005028	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
399742005029	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742005030	dimer interface [polypeptide binding]; other site
399742005031	conserved gate region; other site
399742005032	putative PBP binding loops; other site
399742005033	ABC-ATPase subunit interface; other site
399742005034	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
399742005035	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
399742005036	active site
399742005037	dimer interface [polypeptide binding]; other site
399742005038	non-prolyl cis peptide bond; other site
399742005039	insertion regions; other site
399742005040	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
399742005041	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742005042	substrate binding pocket [chemical binding]; other site
399742005043	membrane-bound complex binding site; other site
399742005044	hinge residues; other site
399742005045	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
399742005046	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742005047	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
399742005048	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
399742005049	quinone interaction residues [chemical binding]; other site
399742005050	active site
399742005051	catalytic residues [active]
399742005052	FMN binding site [chemical binding]; other site
399742005053	substrate binding site [chemical binding]; other site
399742005054	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
399742005055	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
399742005056	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
399742005057	MOSC domain; Region: MOSC; pfam03473
399742005058	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
399742005059	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
399742005060	catalytic loop [active]
399742005061	iron binding site [ion binding]; other site
399742005062	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
399742005063	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
399742005064	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
399742005065	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742005066	S-adenosylmethionine binding site [chemical binding]; other site
399742005067	ABC transporter ATPase component; Reviewed; Region: PRK11147
399742005068	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742005069	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742005070	Walker A/P-loop; other site
399742005071	Walker A/P-loop; other site
399742005072	ATP binding site [chemical binding]; other site
399742005073	ATP binding site [chemical binding]; other site
399742005074	Q-loop/lid; other site
399742005075	Q-loop/lid; other site
399742005076	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742005077	ABC transporter signature motif; other site
399742005078	Walker B; other site
399742005079	D-loop; other site
399742005080	ABC transporter; Region: ABC_tran_2; pfam12848
399742005081	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742005082	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
399742005083	Paraquat-inducible protein A; Region: PqiA; pfam04403
399742005084	Paraquat-inducible protein A; Region: PqiA; pfam04403
399742005085	paraquat-inducible protein B; Provisional; Region: PRK10807
399742005086	mce related protein; Region: MCE; pfam02470
399742005087	mce related protein; Region: MCE; pfam02470
399742005088	mce related protein; Region: MCE; pfam02470
399742005089	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
399742005090	Protein of unknown function (DUF330); Region: DUF330; pfam03886
399742005091	ribosome modulation factor; Provisional; Region: PRK14563
399742005092	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
399742005093	active site 1 [active]
399742005094	dimer interface [polypeptide binding]; other site
399742005095	active site 2 [active]
399742005096	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
399742005097	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
399742005098	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
399742005099	outer membrane protein A; Reviewed; Region: PRK10808
399742005100	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
399742005101	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
399742005102	ligand binding site [chemical binding]; other site
399742005103	SOS cell division inhibitor; Provisional; Region: PRK10595
399742005104	TfoX N-terminal domain; Region: TfoX_N; pfam04993
399742005105	TfoX C-terminal domain; Region: TfoX_C; pfam04994
399742005106	TIGR01666 family membrane protein; Region: YCCS
399742005107	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
399742005108	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
399742005109	Predicted membrane protein [Function unknown]; Region: COG3304
399742005110	Domain of unknown function (DUF307); Region: DUF307; pfam03733
399742005111	Domain of unknown function (DUF307); Region: DUF307; pfam03733
399742005112	DNA helicase IV; Provisional; Region: helD; PRK11054
399742005113	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
399742005114	Part of AAA domain; Region: AAA_19; pfam13245
399742005115	Family description; Region: UvrD_C_2; pfam13538
399742005116	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
399742005117	active site
399742005118	dimer interfaces [polypeptide binding]; other site
399742005119	catalytic residues [active]
399742005120	hypothetical protein; Provisional; Region: PRK03641
399742005121	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
399742005122	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
399742005123	heat shock protein HspQ; Provisional; Region: PRK14129
399742005124	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
399742005125	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
399742005126	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
399742005127	putative RNA binding site [nucleotide binding]; other site
399742005128	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742005129	S-adenosylmethionine binding site [chemical binding]; other site
399742005130	acylphosphatase; Provisional; Region: PRK14426
399742005131	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
399742005132	sulfur transfer protein TusE; Provisional; Region: PRK11508
399742005133	YccA-like proteins; Region: YccA_like; cd10433
399742005134	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
399742005135	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
399742005136	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
399742005137	peptide binding site [polypeptide binding]; other site
399742005138	Protein of unknown function (DUF3833); Region: DUF3833; pfam12915
399742005139	Protein of unknown function (DUF2878); Region: DUF2878; pfam11086
399742005140	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
399742005141	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742005142	S-adenosylmethionine binding site [chemical binding]; other site
399742005143	Protein of unknown function (DUF1365); Region: DUF1365; pfam07103
399742005144	Predicted NAD/FAD-binding protein [General function prediction only]; Region: COG2907
399742005145	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
399742005146	short chain dehydrogenase; Provisional; Region: PRK06101
399742005147	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742005148	NAD(P) binding site [chemical binding]; other site
399742005149	active site
399742005150	SnoaL-like domain; Region: SnoaL_2; pfam12680
399742005151	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742005152	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742005153	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
399742005154	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
399742005155	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
399742005156	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
399742005157	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
399742005158	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
399742005159	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742005160	active site
399742005161	phosphorylation site [posttranslational modification]
399742005162	intermolecular recognition site; other site
399742005163	dimerization interface [polypeptide binding]; other site
399742005164	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742005165	DNA binding site [nucleotide binding]
399742005166	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
399742005167	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742005168	dimerization interface [polypeptide binding]; other site
399742005169	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742005170	dimer interface [polypeptide binding]; other site
399742005171	phosphorylation site [posttranslational modification]
399742005172	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742005173	ATP binding site [chemical binding]; other site
399742005174	Mg2+ binding site [ion binding]; other site
399742005175	G-X-G motif; other site
399742005176	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
399742005177	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
399742005178	active site
399742005179	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
399742005180	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
399742005181	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742005182	Coenzyme A binding pocket [chemical binding]; other site
399742005183	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
399742005184	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
399742005185	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
399742005186	active site
399742005187	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
399742005188	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
399742005189	Sulfatase; Region: Sulfatase; pfam00884
399742005190	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
399742005191	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742005192	FeS/SAM binding site; other site
399742005193	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
399742005194	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
399742005195	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
399742005196	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
399742005197	short chain dehydrogenase; Provisional; Region: PRK06500
399742005198	classical (c) SDRs; Region: SDR_c; cd05233
399742005199	NAD(P) binding site [chemical binding]; other site
399742005200	active site
399742005201	Predicted transcriptional regulators [Transcription]; Region: COG1733
399742005202	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
399742005203	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
399742005204	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742005205	NAD(P) binding site [chemical binding]; other site
399742005206	active site
399742005207	Predicted transcriptional regulators [Transcription]; Region: COG1733
399742005208	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
399742005209	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
399742005210	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
399742005211	catalytic core [active]
399742005212	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
399742005213	hypothetical protein; Provisional; Region: PRK10174
399742005214	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
399742005215	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742005216	General stress protein [General function prediction only]; Region: GsiB; COG3729
399742005217	EamA-like transporter family; Region: EamA; pfam00892
399742005218	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
399742005219	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
399742005220	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
399742005221	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
399742005222	putative FMN binding site [chemical binding]; other site
399742005223	pyrimidine utilization protein D; Region: RutD; TIGR03611
399742005224	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
399742005225	homotrimer interaction site [polypeptide binding]; other site
399742005226	putative active site [active]
399742005227	Isochorismatase family; Region: Isochorismatase; pfam00857
399742005228	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
399742005229	catalytic triad [active]
399742005230	conserved cis-peptide bond; other site
399742005231	pyrimidine utilization protein A; Region: RutA; TIGR03612
399742005232	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
399742005233	active site
399742005234	dimer interface [polypeptide binding]; other site
399742005235	non-prolyl cis peptide bond; other site
399742005236	insertion regions; other site
399742005237	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
399742005238	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
399742005239	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742005240	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
399742005241	dimerization interface [polypeptide binding]; other site
399742005242	substrate binding pocket [chemical binding]; other site
399742005243	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
399742005244	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742005245	NAD(P) binding site [chemical binding]; other site
399742005246	active site
399742005247	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
399742005248	Transposase; Region: DEDD_Tnp_IS110; pfam01548
399742005249	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
399742005250	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
399742005251	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742005252	putative substrate translocation pore; other site
399742005253	Cupin; Region: Cupin_6; pfam12852
399742005254	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742005255	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742005256	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742005257	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
399742005258	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
399742005259	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742005260	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742005261	metal binding site [ion binding]; metal-binding site
399742005262	active site
399742005263	I-site; other site
399742005264	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742005265	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
399742005266	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
399742005267	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742005268	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
399742005269	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
399742005270	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
399742005271	Predicted transcriptional regulator [Transcription]; Region: COG3905
399742005272	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
399742005273	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
399742005274	Glutamate binding site [chemical binding]; other site
399742005275	NAD binding site [chemical binding]; other site
399742005276	catalytic residues [active]
399742005277	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
399742005278	Na binding site [ion binding]; other site
399742005279	Protein of unknown function (DUF3574); Region: DUF3574; pfam12098
399742005280	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
399742005281	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
399742005282	Nucleoside recognition; Region: Gate; pfam07670
399742005283	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
399742005284	FTR1 family protein; Region: TIGR00145
399742005285	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
399742005286	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
399742005287	Imelysin; Region: Peptidase_M75; pfam09375
399742005288	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
399742005289	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
399742005290	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
399742005291	hypothetical protein; Provisional; Region: PRK10536
399742005292	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
399742005293	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
399742005294	putative ligand binding site [chemical binding]; other site
399742005295	NAD binding site [chemical binding]; other site
399742005296	dimerization interface [polypeptide binding]; other site
399742005297	catalytic site [active]
399742005298	putative hydrolase; Validated; Region: PRK09248
399742005299	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
399742005300	active site
399742005301	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
399742005302	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
399742005303	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
399742005304	curli assembly protein CsgF; Provisional; Region: PRK10050
399742005305	curli assembly protein CsgE; Provisional; Region: PRK10386
399742005306	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
399742005307	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742005308	DNA binding residues [nucleotide binding]
399742005309	dimerization interface [polypeptide binding]; other site
399742005310	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
399742005311	Curlin associated repeat; Region: Curlin_rpt; pfam07012
399742005312	Curlin associated repeat; Region: Curlin_rpt; pfam07012
399742005313	major curlin subunit; Provisional; Region: csgA; PRK10051
399742005314	Curlin associated repeat; Region: Curlin_rpt; pfam07012
399742005315	Curlin associated repeat; Region: Curlin_rpt; pfam07012
399742005316	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
399742005317	Fimbrial protein; Region: Fimbrial; cl01416
399742005318	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
399742005319	putative ADP-ribose binding site [chemical binding]; other site
399742005320	putative active site [active]
399742005321	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
399742005322	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
399742005323	putative active site [active]
399742005324	catalytic site [active]
399742005325	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
399742005326	putative active site [active]
399742005327	catalytic site [active]
399742005328	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
399742005329	Acyltransferase family; Region: Acyl_transf_3; pfam01757
399742005330	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
399742005331	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
399742005332	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
399742005333	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
399742005334	Ligand binding site; other site
399742005335	DXD motif; other site
399742005336	lipoprotein; Provisional; Region: PRK10175
399742005337	secY/secA suppressor protein; Provisional; Region: PRK11467
399742005338	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
399742005339	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
399742005340	putative acyl-acceptor binding pocket; other site
399742005341	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
399742005342	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
399742005343	active site residue [active]
399742005344	hypothetical protein; Provisional; Region: PRK03757
399742005345	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
399742005346	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
399742005347	hydroxyglutarate oxidase; Provisional; Region: PRK11728
399742005348	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
399742005349	DNA damage-inducible protein I; Provisional; Region: PRK10597
399742005350	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
399742005351	active site
399742005352	substrate binding pocket [chemical binding]; other site
399742005353	dimer interface [polypeptide binding]; other site
399742005354	lipoprotein; Provisional; Region: PRK10598
399742005355	glutaredoxin 2; Provisional; Region: PRK10387
399742005356	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
399742005357	C-terminal domain interface [polypeptide binding]; other site
399742005358	GSH binding site (G-site) [chemical binding]; other site
399742005359	catalytic residues [active]
399742005360	putative dimer interface [polypeptide binding]; other site
399742005361	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
399742005362	N-terminal domain interface [polypeptide binding]; other site
399742005363	multidrug resistance protein MdtH; Provisional; Region: PRK11646
399742005364	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742005365	putative substrate translocation pore; other site
399742005366	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
399742005367	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
399742005368	hypothetical protein; Provisional; Region: PRK11239
399742005369	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
399742005370	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
399742005371	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
399742005372	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
399742005373	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
399742005374	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
399742005375	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
399742005376	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
399742005377	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
399742005378	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
399742005379	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
399742005380	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
399742005381	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
399742005382	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
399742005383	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
399742005384	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
399742005385	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
399742005386	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
399742005387	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
399742005388	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
399742005389	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
399742005390	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
399742005391	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
399742005392	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
399742005393	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
399742005394	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
399742005395	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
399742005396	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
399742005397	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
399742005398	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
399742005399	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
399742005400	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
399742005401	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
399742005402	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
399742005403	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
399742005404	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
399742005405	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
399742005406	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
399742005407	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
399742005408	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
399742005409	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
399742005410	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742005411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742005412	putative substrate translocation pore; other site
399742005413	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742005414	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742005415	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742005416	putative effector binding pocket; other site
399742005417	dimerization interface [polypeptide binding]; other site
399742005418	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
399742005419	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
399742005420	homodimer interface [polypeptide binding]; other site
399742005421	oligonucleotide binding site [chemical binding]; other site
399742005422	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
399742005423	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
399742005424	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742005425	RNA binding surface [nucleotide binding]; other site
399742005426	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
399742005427	active site
399742005428	Maf-like protein; Region: Maf; pfam02545
399742005429	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
399742005430	active site
399742005431	dimer interface [polypeptide binding]; other site
399742005432	hypothetical protein; Provisional; Region: PRK11193
399742005433	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
399742005434	putative phosphate acyltransferase; Provisional; Region: PRK05331
399742005435	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
399742005436	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
399742005437	dimer interface [polypeptide binding]; other site
399742005438	active site
399742005439	CoA binding pocket [chemical binding]; other site
399742005440	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
399742005441	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
399742005442	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
399742005443	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
399742005444	NAD(P) binding site [chemical binding]; other site
399742005445	homotetramer interface [polypeptide binding]; other site
399742005446	homodimer interface [polypeptide binding]; other site
399742005447	active site
399742005448	acyl carrier protein; Provisional; Region: acpP; PRK00982
399742005449	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
399742005450	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
399742005451	dimer interface [polypeptide binding]; other site
399742005452	active site
399742005453	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
399742005454	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
399742005455	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742005456	catalytic residue [active]
399742005457	conserved hypothetical protein, YceG family; Region: TIGR00247
399742005458	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
399742005459	dimerization interface [polypeptide binding]; other site
399742005460	thymidylate kinase; Validated; Region: tmk; PRK00698
399742005461	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
399742005462	TMP-binding site; other site
399742005463	ATP-binding site [chemical binding]; other site
399742005464	DNA polymerase III subunit delta'; Validated; Region: PRK07993
399742005465	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
399742005466	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
399742005467	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
399742005468	active site
399742005469	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
399742005470	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742005471	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742005472	active site turn [active]
399742005473	phosphorylation site [posttranslational modification]
399742005474	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
399742005475	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742005476	N-terminal plug; other site
399742005477	ligand-binding site [chemical binding]; other site
399742005478	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
399742005479	nucleotide binding site/active site [active]
399742005480	HIT family signature motif; other site
399742005481	catalytic residue [active]
399742005482	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
399742005483	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
399742005484	putative dimer interface [polypeptide binding]; other site
399742005485	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
399742005486	thiamine kinase; Region: ycfN_thiK; TIGR02721
399742005487	thiamine kinase; Provisional; Region: thiK; PRK10271
399742005488	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
399742005489	beta-hexosaminidase; Provisional; Region: PRK05337
399742005490	hypothetical protein; Provisional; Region: PRK04940
399742005491	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
399742005492	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742005493	hypothetical protein; Provisional; Region: PRK11280
399742005494	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742005495	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742005496	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742005497	L,D-transpeptidase; Provisional; Region: PRK10190
399742005498	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742005499	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
399742005500	transcription-repair coupling factor; Provisional; Region: PRK10689
399742005501	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
399742005502	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742005503	ATP binding site [chemical binding]; other site
399742005504	putative Mg++ binding site [ion binding]; other site
399742005505	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742005506	nucleotide binding region [chemical binding]; other site
399742005507	ATP-binding site [chemical binding]; other site
399742005508	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
399742005509	Predicted membrane protein [Function unknown]; Region: COG4763
399742005510	Acyltransferase family; Region: Acyl_transf_3; pfam01757
399742005511	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
399742005512	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
399742005513	FtsX-like permease family; Region: FtsX; pfam02687
399742005514	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
399742005515	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
399742005516	Walker A/P-loop; other site
399742005517	ATP binding site [chemical binding]; other site
399742005518	Q-loop/lid; other site
399742005519	ABC transporter signature motif; other site
399742005520	Walker B; other site
399742005521	D-loop; other site
399742005522	H-loop/switch region; other site
399742005523	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
399742005524	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
399742005525	FtsX-like permease family; Region: FtsX; pfam02687
399742005526	fructokinase; Reviewed; Region: PRK09557
399742005527	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742005528	nucleotide binding site [chemical binding]; other site
399742005529	NAD-dependent deacetylase; Provisional; Region: PRK00481
399742005530	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
399742005531	NAD+ binding site [chemical binding]; other site
399742005532	substrate binding site [chemical binding]; other site
399742005533	Zn binding site [ion binding]; other site
399742005534	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
399742005535	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
399742005536	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
399742005537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742005538	dimer interface [polypeptide binding]; other site
399742005539	conserved gate region; other site
399742005540	putative PBP binding loops; other site
399742005541	ABC-ATPase subunit interface; other site
399742005542	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742005543	dimer interface [polypeptide binding]; other site
399742005544	conserved gate region; other site
399742005545	putative PBP binding loops; other site
399742005546	ABC-ATPase subunit interface; other site
399742005547	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
399742005548	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742005549	Walker A/P-loop; other site
399742005550	ATP binding site [chemical binding]; other site
399742005551	Q-loop/lid; other site
399742005552	ABC transporter signature motif; other site
399742005553	Walker B; other site
399742005554	D-loop; other site
399742005555	H-loop/switch region; other site
399742005556	TOBE domain; Region: TOBE_2; pfam08402
399742005557	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
399742005558	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
399742005559	metal binding site [ion binding]; metal-binding site
399742005560	dimer interface [polypeptide binding]; other site
399742005561	Uncharacterized conserved protein [Function unknown]; Region: COG2850
399742005562	sensor protein PhoQ; Provisional; Region: PRK10815
399742005563	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
399742005564	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
399742005565	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742005566	ATP binding site [chemical binding]; other site
399742005567	Mg2+ binding site [ion binding]; other site
399742005568	G-X-G motif; other site
399742005569	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
399742005570	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742005571	active site
399742005572	phosphorylation site [posttranslational modification]
399742005573	intermolecular recognition site; other site
399742005574	dimerization interface [polypeptide binding]; other site
399742005575	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742005576	DNA binding site [nucleotide binding]
399742005577	adenylosuccinate lyase; Provisional; Region: PRK09285
399742005578	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
399742005579	tetramer interface [polypeptide binding]; other site
399742005580	active site
399742005581	putative lysogenization regulator; Reviewed; Region: PRK00218
399742005582	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
399742005583	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
399742005584	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
399742005585	nudix motif; other site
399742005586	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
399742005587	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
399742005588	probable active site [active]
399742005589	isocitrate dehydrogenase; Validated; Region: PRK07362
399742005590	isocitrate dehydrogenase; Reviewed; Region: PRK07006
399742005591	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
399742005592	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
399742005593	dimer interface [polypeptide binding]; other site
399742005594	active site
399742005595	Int/Topo IB signature motif; other site
399742005596	Phage terminase, small subunit; Region: Terminase_4; pfam05119
399742005597	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
399742005598	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
399742005599	DinI-like family; Region: DinI; pfam06183
399742005600	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
399742005601	hypothetical protein; Provisional; Region: PRK10457
399742005602	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
399742005603	GAF domain; Region: GAF; pfam01590
399742005604	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742005605	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742005606	metal binding site [ion binding]; metal-binding site
399742005607	active site
399742005608	I-site; other site
399742005609	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
399742005610	Domain of unknown function (DUF333); Region: DUF333; pfam03891
399742005611	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
399742005612	Uncharacterized conserved protein [Function unknown]; Region: COG3189
399742005613	Uncharacterized conserved protein [Function unknown]; Region: COG1683
399742005614	hypothetical protein; Validated; Region: PRK06186
399742005615	conserved cys residue [active]
399742005616	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
399742005617	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742005618	putative substrate translocation pore; other site
399742005619	Cupin domain; Region: Cupin_2; cl17218
399742005620	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742005621	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742005622	Predicted membrane protein [Function unknown]; Region: COG2707
399742005623	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
399742005624	putative deacylase active site [active]
399742005625	diguanylate cyclase; Provisional; Region: PRK09894
399742005626	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
399742005627	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742005628	metal binding site [ion binding]; metal-binding site
399742005629	active site
399742005630	I-site; other site
399742005631	hypothetical protein; Provisional; Region: PRK05325
399742005632	PrkA family serine protein kinase; Provisional; Region: PRK15455
399742005633	AAA ATPase domain; Region: AAA_16; pfam13191
399742005634	Walker A motif; other site
399742005635	ATP binding site [chemical binding]; other site
399742005636	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
399742005637	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
399742005638	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742005639	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742005640	active site
399742005641	catalytic tetrad [active]
399742005642	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
399742005643	active site
399742005644	phosphate binding residues; other site
399742005645	catalytic residues [active]
399742005646	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
399742005647	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
399742005648	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
399742005649	methionine sulfoxide reductase B; Provisional; Region: PRK00222
399742005650	SelR domain; Region: SelR; pfam01641
399742005651	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
399742005652	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
399742005653	active site
399742005654	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
399742005655	Isochorismatase family; Region: Isochorismatase; pfam00857
399742005656	catalytic triad [active]
399742005657	metal binding site [ion binding]; metal-binding site
399742005658	conserved cis-peptide bond; other site
399742005659	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
399742005660	active site
399742005661	homodimer interface [polypeptide binding]; other site
399742005662	protease 4; Provisional; Region: PRK10949
399742005663	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
399742005664	tandem repeat interface [polypeptide binding]; other site
399742005665	oligomer interface [polypeptide binding]; other site
399742005666	active site residues [active]
399742005667	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
399742005668	tandem repeat interface [polypeptide binding]; other site
399742005669	oligomer interface [polypeptide binding]; other site
399742005670	active site residues [active]
399742005671	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
399742005672	putative FMN binding site [chemical binding]; other site
399742005673	selenophosphate synthetase; Provisional; Region: PRK00943
399742005674	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
399742005675	dimerization interface [polypeptide binding]; other site
399742005676	putative ATP binding site [chemical binding]; other site
399742005677	DNA topoisomerase III; Provisional; Region: PRK07726
399742005678	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
399742005679	active site
399742005680	putative interdomain interaction site [polypeptide binding]; other site
399742005681	putative metal-binding site [ion binding]; other site
399742005682	putative nucleotide binding site [chemical binding]; other site
399742005683	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
399742005684	domain I; other site
399742005685	DNA binding groove [nucleotide binding]
399742005686	phosphate binding site [ion binding]; other site
399742005687	domain II; other site
399742005688	domain III; other site
399742005689	nucleotide binding site [chemical binding]; other site
399742005690	catalytic site [active]
399742005691	domain IV; other site
399742005692	glutamate dehydrogenase; Provisional; Region: PRK09414
399742005693	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
399742005694	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
399742005695	NAD(P) binding site [chemical binding]; other site
399742005696	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
399742005697	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
399742005698	active site
399742005699	8-oxo-dGMP binding site [chemical binding]; other site
399742005700	nudix motif; other site
399742005701	metal binding site [ion binding]; metal-binding site
399742005702	Uncharacterized conserved protein [Function unknown]; Region: COG2128
399742005703	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
399742005704	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
399742005705	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
399742005706	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
399742005707	active site residue [active]
399742005708	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
399742005709	active site residue [active]
399742005710	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
399742005711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742005712	Walker A/P-loop; other site
399742005713	ATP binding site [chemical binding]; other site
399742005714	Q-loop/lid; other site
399742005715	ABC transporter signature motif; other site
399742005716	Walker B; other site
399742005717	D-loop; other site
399742005718	H-loop/switch region; other site
399742005719	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
399742005720	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742005721	dimer interface [polypeptide binding]; other site
399742005722	conserved gate region; other site
399742005723	putative PBP binding loops; other site
399742005724	ABC-ATPase subunit interface; other site
399742005725	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742005726	ABC-ATPase subunit interface; other site
399742005727	putative PBP binding loops; other site
399742005728	hypothetical protein; Provisional; Region: PRK11622
399742005729	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
399742005730	Uncharacterized conserved protein [Function unknown]; Region: COG0398
399742005731	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
399742005732	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
399742005733	putative catalytic site [active]
399742005734	putative phosphate binding site [ion binding]; other site
399742005735	active site
399742005736	metal binding site A [ion binding]; metal-binding site
399742005737	DNA binding site [nucleotide binding]
399742005738	putative AP binding site [nucleotide binding]; other site
399742005739	putative metal binding site B [ion binding]; other site
399742005740	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
399742005741	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742005742	inhibitor-cofactor binding pocket; inhibition site
399742005743	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742005744	catalytic residue [active]
399742005745	arginine succinyltransferase; Provisional; Region: PRK10456
399742005746	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
399742005747	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
399742005748	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
399742005749	NAD(P) binding site [chemical binding]; other site
399742005750	catalytic residues [active]
399742005751	succinylarginine dihydrolase; Provisional; Region: PRK13281
399742005752	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
399742005753	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
399742005754	putative active site [active]
399742005755	Zn binding site [ion binding]; other site
399742005756	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
399742005757	dimer interface [polypeptide binding]; other site
399742005758	hypothetical protein; Provisional; Region: PRK11396
399742005759	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
399742005760	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
399742005761	GIY-YIG motif/motif A; other site
399742005762	active site
399742005763	catalytic site [active]
399742005764	putative DNA binding site [nucleotide binding]; other site
399742005765	metal binding site [ion binding]; metal-binding site
399742005766	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
399742005767	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
399742005768	homodimer interface [polypeptide binding]; other site
399742005769	NAD binding pocket [chemical binding]; other site
399742005770	ATP binding pocket [chemical binding]; other site
399742005771	Mg binding site [ion binding]; other site
399742005772	active-site loop [active]
399742005773	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
399742005774	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
399742005775	active site
399742005776	P-loop; other site
399742005777	phosphorylation site [posttranslational modification]
399742005778	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
399742005779	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
399742005780	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
399742005781	methionine cluster; other site
399742005782	active site
399742005783	phosphorylation site [posttranslational modification]
399742005784	metal binding site [ion binding]; metal-binding site
399742005785	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
399742005786	Cupin domain; Region: Cupin_2; pfam07883
399742005787	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
399742005788	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
399742005789	NAD binding site [chemical binding]; other site
399742005790	sugar binding site [chemical binding]; other site
399742005791	divalent metal binding site [ion binding]; other site
399742005792	tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742005793	dimer interface [polypeptide binding]; other site
399742005794	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
399742005795	putative active site [active]
399742005796	YdjC motif; other site
399742005797	Mg binding site [ion binding]; other site
399742005798	putative homodimer interface [polypeptide binding]; other site
399742005799	hydroperoxidase II; Provisional; Region: katE; PRK11249
399742005800	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
399742005801	tetramer interface [polypeptide binding]; other site
399742005802	heme binding pocket [chemical binding]; other site
399742005803	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
399742005804	domain interactions; other site
399742005805	cell division modulator; Provisional; Region: PRK10113
399742005806	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
399742005807	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
399742005808	inner membrane protein; Provisional; Region: PRK11648
399742005809	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
399742005810	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
399742005811	NADP binding site [chemical binding]; other site
399742005812	homodimer interface [polypeptide binding]; other site
399742005813	active site
399742005814	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
399742005815	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
399742005816	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742005817	motif II; other site
399742005818	YniB-like protein; Region: YniB; pfam14002
399742005819	Phosphotransferase enzyme family; Region: APH; pfam01636
399742005820	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
399742005821	active site
399742005822	ATP binding site [chemical binding]; other site
399742005823	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
399742005824	active site
399742005825	ATP binding site [chemical binding]; other site
399742005826	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
399742005827	6-phosphofructokinase 2; Provisional; Region: PRK10294
399742005828	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
399742005829	putative substrate binding site [chemical binding]; other site
399742005830	putative ATP binding site [chemical binding]; other site
399742005831	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
399742005832	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
399742005833	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
399742005834	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
399742005835	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
399742005836	active site
399742005837	dimer interface [polypeptide binding]; other site
399742005838	motif 1; other site
399742005839	motif 2; other site
399742005840	motif 3; other site
399742005841	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
399742005842	anticodon binding site; other site
399742005843	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
399742005844	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
399742005845	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
399742005846	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
399742005847	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
399742005848	23S rRNA binding site [nucleotide binding]; other site
399742005849	L21 binding site [polypeptide binding]; other site
399742005850	L13 binding site [polypeptide binding]; other site
399742005851	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
399742005852	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
399742005853	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
399742005854	dimer interface [polypeptide binding]; other site
399742005855	motif 1; other site
399742005856	active site
399742005857	motif 2; other site
399742005858	motif 3; other site
399742005859	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
399742005860	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
399742005861	putative tRNA-binding site [nucleotide binding]; other site
399742005862	B3/4 domain; Region: B3_4; pfam03483
399742005863	tRNA synthetase B5 domain; Region: B5; smart00874
399742005864	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
399742005865	dimer interface [polypeptide binding]; other site
399742005866	motif 1; other site
399742005867	motif 3; other site
399742005868	motif 2; other site
399742005869	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
399742005870	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
399742005871	IHF dimer interface [polypeptide binding]; other site
399742005872	IHF - DNA interface [nucleotide binding]; other site
399742005873	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
399742005874	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742005875	ABC-ATPase subunit  interface; other site
399742005876	dimer interface [polypeptide binding]; other site
399742005877	putative PBP binding regions; other site
399742005878	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
399742005879	catalytic residues [active]
399742005880	dimer interface [polypeptide binding]; other site
399742005881	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
399742005882	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742005883	Walker A/P-loop; other site
399742005884	ATP binding site [chemical binding]; other site
399742005885	Q-loop/lid; other site
399742005886	ABC transporter signature motif; other site
399742005887	Walker B; other site
399742005888	D-loop; other site
399742005889	H-loop/switch region; other site
399742005890	Type VI secretion lipoprotein; Region: T6SS-SciN; cl01405
399742005891	NlpC/P60 family; Region: NLPC_P60; pfam00877
399742005892	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
399742005893	Uncharacterized conserved protein [Function unknown]; Region: COG0397
399742005894	hypothetical protein; Validated; Region: PRK00029
399742005895	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
399742005896	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742005897	Walker A/P-loop; other site
399742005898	ATP binding site [chemical binding]; other site
399742005899	Q-loop/lid; other site
399742005900	ABC transporter signature motif; other site
399742005901	Walker B; other site
399742005902	D-loop; other site
399742005903	H-loop/switch region; other site
399742005904	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
399742005905	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742005906	ABC-ATPase subunit  interface; other site
399742005907	dimer interface [polypeptide binding]; other site
399742005908	putative PBP binding regions; other site
399742005909	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
399742005910	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
399742005911	putative hemin binding site; other site
399742005912	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
399742005913	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
399742005914	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
399742005915	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
399742005916	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742005917	N-terminal plug; other site
399742005918	ligand-binding site [chemical binding]; other site
399742005919	hypothetical protein; Provisional; Region: PRK10183
399742005920	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
399742005921	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
399742005922	PEP synthetase regulatory protein; Provisional; Region: PRK05339
399742005923	phosphoenolpyruvate synthase; Validated; Region: PRK06464
399742005924	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
399742005925	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
399742005926	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
399742005927	putative inner membrane protein; Provisional; Region: PRK10983
399742005928	Domain of unknown function DUF20; Region: UPF0118; pfam01594
399742005929	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
399742005930	FAD binding domain; Region: FAD_binding_4; pfam01565
399742005931	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
399742005932	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
399742005933	CoenzymeA binding site [chemical binding]; other site
399742005934	subunit interaction site [polypeptide binding]; other site
399742005935	PHB binding site; other site
399742005936	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
399742005937	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
399742005938	[4Fe-4S] binding site [ion binding]; other site
399742005939	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742005940	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
399742005941	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
399742005942	molybdopterin cofactor binding site; other site
399742005943	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
399742005944	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
399742005945	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
399742005946	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
399742005947	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
399742005948	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
399742005949	[4Fe-4S] binding site [ion binding]; other site
399742005950	molybdopterin cofactor binding site; other site
399742005951	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
399742005952	molybdopterin cofactor binding site; other site
399742005953	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
399742005954	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
399742005955	Sensors of blue-light using FAD; Region: BLUF; smart01034
399742005956	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742005957	transcriptional regulator MirA; Provisional; Region: PRK15043
399742005958	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
399742005959	DNA binding residues [nucleotide binding]
399742005960	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
399742005961	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
399742005962	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
399742005963	putative ABC transporter; Region: ycf24; CHL00085
399742005964	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
399742005965	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
399742005966	Walker A/P-loop; other site
399742005967	ATP binding site [chemical binding]; other site
399742005968	Q-loop/lid; other site
399742005969	ABC transporter signature motif; other site
399742005970	Walker B; other site
399742005971	D-loop; other site
399742005972	H-loop/switch region; other site
399742005973	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
399742005974	FeS assembly protein SufD; Region: sufD; TIGR01981
399742005975	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
399742005976	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
399742005977	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
399742005978	catalytic residue [active]
399742005979	cysteine desufuration protein SufE; Provisional; Region: PRK09296
399742005980	L,D-transpeptidase; Provisional; Region: PRK10260
399742005981	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742005982	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
399742005983	murein lipoprotein; Provisional; Region: PRK15396
399742005984	pyruvate kinase; Provisional; Region: PRK09206
399742005985	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
399742005986	domain interfaces; other site
399742005987	active site
399742005988	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
399742005989	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
399742005990	homodimer interface [polypeptide binding]; other site
399742005991	substrate-cofactor binding pocket; other site
399742005992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742005993	catalytic residue [active]
399742005994	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
399742005995	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
399742005996	dimer interface [polypeptide binding]; other site
399742005997	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742005998	catalytic residue [active]
399742005999	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
399742006000	FOG: CBS domain [General function prediction only]; Region: COG0517
399742006001	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
399742006002	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
399742006003	Walker A/P-loop; other site
399742006004	ATP binding site [chemical binding]; other site
399742006005	Q-loop/lid; other site
399742006006	ABC transporter signature motif; other site
399742006007	Walker B; other site
399742006008	D-loop; other site
399742006009	H-loop/switch region; other site
399742006010	NIL domain; Region: NIL; pfam09383
399742006011	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006012	dimer interface [polypeptide binding]; other site
399742006013	conserved gate region; other site
399742006014	putative PBP binding loops; other site
399742006015	ABC-ATPase subunit interface; other site
399742006016	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
399742006017	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
399742006018	hypothetical protein; Provisional; Region: PRK10292
399742006019	Autotransporter beta-domain; Region: Autotransporter; smart00869
399742006020	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006021	dimer interface [polypeptide binding]; other site
399742006022	conserved gate region; other site
399742006023	putative PBP binding loops; other site
399742006024	ABC-ATPase subunit interface; other site
399742006025	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006026	dimer interface [polypeptide binding]; other site
399742006027	conserved gate region; other site
399742006028	putative PBP binding loops; other site
399742006029	ABC-ATPase subunit interface; other site
399742006030	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
399742006031	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
399742006032	Walker A/P-loop; other site
399742006033	ATP binding site [chemical binding]; other site
399742006034	Q-loop/lid; other site
399742006035	ABC transporter signature motif; other site
399742006036	Walker B; other site
399742006037	D-loop; other site
399742006038	H-loop/switch region; other site
399742006039	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
399742006040	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742006041	substrate binding pocket [chemical binding]; other site
399742006042	membrane-bound complex binding site; other site
399742006043	hinge residues; other site
399742006044	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
399742006045	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
399742006046	active site clefts [active]
399742006047	zinc binding site [ion binding]; other site
399742006048	dimer interface [polypeptide binding]; other site
399742006049	hypothetical protein; Provisional; Region: PRK09897
399742006050	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
399742006051	multidrug efflux protein; Reviewed; Region: PRK01766
399742006052	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
399742006053	cation binding site [ion binding]; other site
399742006054	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
399742006055	Lumazine binding domain; Region: Lum_binding; pfam00677
399742006056	Lumazine binding domain; Region: Lum_binding; pfam00677
399742006057	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
399742006058	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
399742006059	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
399742006060	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742006061	S-adenosylmethionine binding site [chemical binding]; other site
399742006062	putative transporter; Provisional; Region: PRK11043
399742006063	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006064	putative substrate translocation pore; other site
399742006065	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
399742006066	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006067	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742006068	dimerization interface [polypeptide binding]; other site
399742006069	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
399742006070	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742006071	DNA binding site [nucleotide binding]
399742006072	domain linker motif; other site
399742006073	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
399742006074	dimerization interface [polypeptide binding]; other site
399742006075	ligand binding site [chemical binding]; other site
399742006076	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006077	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742006078	putative substrate translocation pore; other site
399742006079	superoxide dismutase; Provisional; Region: PRK10543
399742006080	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
399742006081	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
399742006082	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
399742006083	NlpC/P60 family; Region: NLPC_P60; pfam00877
399742006084	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
399742006085	putative GSH binding site [chemical binding]; other site
399742006086	catalytic residues [active]
399742006087	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
399742006088	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
399742006089	dimer interface [polypeptide binding]; other site
399742006090	catalytic site [active]
399742006091	putative active site [active]
399742006092	putative substrate binding site [chemical binding]; other site
399742006093	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742006094	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
399742006095	dimer interface [polypeptide binding]; other site
399742006096	active site
399742006097	metal binding site [ion binding]; metal-binding site
399742006098	glutathione binding site [chemical binding]; other site
399742006099	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
399742006100	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
399742006101	FMN binding site [chemical binding]; other site
399742006102	active site
399742006103	substrate binding site [chemical binding]; other site
399742006104	catalytic residue [active]
399742006105	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742006106	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742006107	putative metal dependent hydrolase; Provisional; Region: PRK11598
399742006108	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
399742006109	Sulfatase; Region: Sulfatase; pfam00884
399742006110	Predicted Fe-S protein [General function prediction only]; Region: COG3313
399742006111	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742006112	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742006113	active site
399742006114	catalytic tetrad [active]
399742006115	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
399742006116	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
399742006117	E-class dimer interface [polypeptide binding]; other site
399742006118	P-class dimer interface [polypeptide binding]; other site
399742006119	active site
399742006120	Cu2+ binding site [ion binding]; other site
399742006121	Zn2+ binding site [ion binding]; other site
399742006122	Fusaric acid resistance protein family; Region: FUSC; pfam04632
399742006123	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
399742006124	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
399742006125	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742006126	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742006127	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
399742006128	transcriptional regulator SlyA; Provisional; Region: PRK03573
399742006129	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
399742006130	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742006131	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742006132	metal binding site [ion binding]; metal-binding site
399742006133	active site
399742006134	I-site; other site
399742006135	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
399742006136	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
399742006137	lysozyme inhibitor; Provisional; Region: PRK11372
399742006138	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
399742006139	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
399742006140	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
399742006141	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
399742006142	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
399742006143	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
399742006144	active site
399742006145	HIGH motif; other site
399742006146	dimer interface [polypeptide binding]; other site
399742006147	KMSKS motif; other site
399742006148	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742006149	RNA binding surface [nucleotide binding]; other site
399742006150	pyridoxamine kinase; Validated; Region: PRK05756
399742006151	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
399742006152	dimer interface [polypeptide binding]; other site
399742006153	pyridoxal binding site [chemical binding]; other site
399742006154	ATP binding site [chemical binding]; other site
399742006155	glutathionine S-transferase; Provisional; Region: PRK10542
399742006156	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
399742006157	C-terminal domain interface [polypeptide binding]; other site
399742006158	GSH binding site (G-site) [chemical binding]; other site
399742006159	dimer interface [polypeptide binding]; other site
399742006160	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
399742006161	N-terminal domain interface [polypeptide binding]; other site
399742006162	dimer interface [polypeptide binding]; other site
399742006163	substrate binding pocket (H-site) [chemical binding]; other site
399742006164	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
399742006165	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006166	putative substrate translocation pore; other site
399742006167	POT family; Region: PTR2; pfam00854
399742006168	endonuclease III; Provisional; Region: PRK10702
399742006169	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
399742006170	minor groove reading motif; other site
399742006171	helix-hairpin-helix signature motif; other site
399742006172	substrate binding pocket [chemical binding]; other site
399742006173	active site
399742006174	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
399742006175	electron transport complex RsxE subunit; Provisional; Region: PRK12405
399742006176	electron transport complex protein RnfG; Validated; Region: PRK01908
399742006177	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
399742006178	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
399742006179	SLBB domain; Region: SLBB; pfam10531
399742006180	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
399742006181	ferredoxin; Provisional; Region: PRK08764
399742006182	Putative Fe-S cluster; Region: FeS; cl17515
399742006183	4Fe-4S binding domain; Region: Fer4; pfam00037
399742006184	electron transport complex protein RsxA; Provisional; Region: PRK05151
399742006185	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
399742006186	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
399742006187	putative oxidoreductase; Provisional; Region: PRK11579
399742006188	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
399742006189	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
399742006190	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
399742006191	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
399742006192	active site
399742006193	purine riboside binding site [chemical binding]; other site
399742006194	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
399742006195	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742006196	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742006197	homodimer interface [polypeptide binding]; other site
399742006198	catalytic residue [active]
399742006199	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
399742006200	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
399742006201	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742006202	active site turn [active]
399742006203	phosphorylation site [posttranslational modification]
399742006204	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
399742006205	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742006206	DNA binding site [nucleotide binding]
399742006207	domain linker motif; other site
399742006208	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
399742006209	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
399742006210	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
399742006211	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
399742006212	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
399742006213	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
399742006214	fumarate hydratase; Provisional; Region: PRK15389
399742006215	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
399742006216	Fumarase C-terminus; Region: Fumerase_C; pfam05683
399742006217	fumarate hydratase; Reviewed; Region: fumC; PRK00485
399742006218	Class II fumarases; Region: Fumarase_classII; cd01362
399742006219	active site
399742006220	tetramer interface [polypeptide binding]; other site
399742006221	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
399742006222	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742006223	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
399742006224	substrate binding site [chemical binding]; other site
399742006225	nickel transporter permease NikB; Provisional; Region: PRK10352
399742006226	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006227	dimer interface [polypeptide binding]; other site
399742006228	conserved gate region; other site
399742006229	putative PBP binding loops; other site
399742006230	ABC-ATPase subunit interface; other site
399742006231	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
399742006232	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006233	dimer interface [polypeptide binding]; other site
399742006234	conserved gate region; other site
399742006235	putative PBP binding loops; other site
399742006236	ABC-ATPase subunit interface; other site
399742006237	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
399742006238	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742006239	Walker A/P-loop; other site
399742006240	ATP binding site [chemical binding]; other site
399742006241	Q-loop/lid; other site
399742006242	ABC transporter signature motif; other site
399742006243	Walker B; other site
399742006244	D-loop; other site
399742006245	H-loop/switch region; other site
399742006246	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
399742006247	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742006248	Walker A/P-loop; other site
399742006249	ATP binding site [chemical binding]; other site
399742006250	Q-loop/lid; other site
399742006251	ABC transporter signature motif; other site
399742006252	Walker B; other site
399742006253	D-loop; other site
399742006254	H-loop/switch region; other site
399742006255	nickel responsive regulator; Provisional; Region: PRK02967
399742006256	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
399742006257	sensor protein RstB; Provisional; Region: PRK10604
399742006258	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742006259	dimerization interface [polypeptide binding]; other site
399742006260	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742006261	dimer interface [polypeptide binding]; other site
399742006262	phosphorylation site [posttranslational modification]
399742006263	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742006264	ATP binding site [chemical binding]; other site
399742006265	Mg2+ binding site [ion binding]; other site
399742006266	G-X-G motif; other site
399742006267	Bor protein; Region: Lambda_Bor; pfam06291
399742006268	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
399742006269	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742006270	active site
399742006271	phosphorylation site [posttranslational modification]
399742006272	intermolecular recognition site; other site
399742006273	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742006274	DNA binding site [nucleotide binding]
399742006275	GlpM protein; Region: GlpM; pfam06942
399742006276	dihydromonapterin reductase; Provisional; Region: PRK06483
399742006277	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742006278	NAD(P) binding site [chemical binding]; other site
399742006279	active site
399742006280	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
399742006281	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742006282	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742006283	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742006284	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
399742006285	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
399742006286	ligand binding site [chemical binding]; other site
399742006287	homodimer interface [polypeptide binding]; other site
399742006288	NAD(P) binding site [chemical binding]; other site
399742006289	trimer interface B [polypeptide binding]; other site
399742006290	trimer interface A [polypeptide binding]; other site
399742006291	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
399742006292	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
399742006293	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
399742006294	universal stress protein UspE; Provisional; Region: PRK11175
399742006295	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742006296	Ligand Binding Site [chemical binding]; other site
399742006297	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742006298	Ligand Binding Site [chemical binding]; other site
399742006299	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
399742006300	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
399742006301	ligand binding site [chemical binding]; other site
399742006302	flexible hinge region; other site
399742006303	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
399742006304	putative switch regulator; other site
399742006305	non-specific DNA interactions [nucleotide binding]; other site
399742006306	DNA binding site [nucleotide binding]
399742006307	sequence specific DNA binding site [nucleotide binding]; other site
399742006308	putative cAMP binding site [chemical binding]; other site
399742006309	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
399742006310	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
399742006311	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
399742006312	DNA binding site [nucleotide binding]
399742006313	active site
399742006314	AbgT putative transporter family; Region: ABG_transport; cl17431
399742006315	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
399742006316	Smr domain; Region: Smr; pfam01713
399742006317	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
399742006318	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742006319	dimer interface [polypeptide binding]; other site
399742006320	ligand binding site [chemical binding]; other site
399742006321	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742006322	dimerization interface [polypeptide binding]; other site
399742006323	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742006324	dimer interface [polypeptide binding]; other site
399742006325	putative CheW interface [polypeptide binding]; other site
399742006326	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742006327	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742006328	active site
399742006329	catalytic tetrad [active]
399742006330	MltA-interacting protein MipA; Region: MipA; cl01504
399742006331	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
399742006332	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742006333	active site
399742006334	phosphorylation site [posttranslational modification]
399742006335	intermolecular recognition site; other site
399742006336	dimerization interface [polypeptide binding]; other site
399742006337	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742006338	DNA binding site [nucleotide binding]
399742006339	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
399742006340	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
399742006341	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742006342	dimer interface [polypeptide binding]; other site
399742006343	phosphorylation site [posttranslational modification]
399742006344	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742006345	ATP binding site [chemical binding]; other site
399742006346	Mg2+ binding site [ion binding]; other site
399742006347	G-X-G motif; other site
399742006348	H+ Antiporter protein; Region: 2A0121; TIGR00900
399742006349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006350	putative substrate translocation pore; other site
399742006351	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
399742006352	YadA-like C-terminal region; Region: YadA; pfam03895
399742006353	Uncharacterized conserved protein [Function unknown]; Region: COG1359
399742006354	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
399742006355	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
399742006356	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742006357	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742006358	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
399742006359	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742006360	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742006361	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
399742006362	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
399742006363	Uncharacterized conserved protein [Function unknown]; Region: COG1359
399742006364	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742006365	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742006366	active site
399742006367	catalytic tetrad [active]
399742006368	YCII-related domain; Region: YCII; cl00999
399742006369	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
399742006370	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742006371	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006372	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742006373	dimerization interface [polypeptide binding]; other site
399742006374	Uncharacterized conserved protein [Function unknown]; Region: COG3391
399742006375	SdiA-regulated; Region: SdiA-regulated; cd09971
399742006376	putative active site [active]
399742006377	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
399742006378	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006379	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742006380	dimerization interface [polypeptide binding]; other site
399742006381	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
399742006382	YebG protein; Region: YebG; pfam07130
399742006383	Predicted amidohydrolase [General function prediction only]; Region: COG0388
399742006384	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_7; cd07585
399742006385	putative active site [active]
399742006386	catalytic triad [active]
399742006387	putative dimer interface [polypeptide binding]; other site
399742006388	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742006389	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006390	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
399742006391	dimerization interface [polypeptide binding]; other site
399742006392	substrate binding pocket [chemical binding]; other site
399742006393	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
399742006394	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006395	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
399742006396	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742006397	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742006398	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
399742006399	Predicted transcriptional regulator [Transcription]; Region: COG1959
399742006400	Transcriptional regulator; Region: Rrf2; pfam02082
399742006401	Transcriptional regulator; Region: Rrf2; cl17282
399742006402	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only]; Region: COG5516
399742006403	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
399742006404	CGNR zinc finger; Region: zf-CGNR; pfam11706
399742006405	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
399742006406	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
399742006407	chorismate mutase; Provisional; Region: PRK08055
399742006408	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742006409	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006410	putative substrate translocation pore; other site
399742006411	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742006412	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006413	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742006414	dimerization interface [polypeptide binding]; other site
399742006415	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
399742006416	outer membrane protease; Reviewed; Region: PRK10993
399742006417	DinB family; Region: DinB; cl17821
399742006418	DinB superfamily; Region: DinB_2; pfam12867
399742006419	LysE type translocator; Region: LysE; cl00565
399742006420	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742006421	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006422	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742006423	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006424	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
399742006425	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742006426	Catalytic site [active]
399742006427	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
399742006428	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
399742006429	active site
399742006430	DNA binding site [nucleotide binding]
399742006431	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
399742006432	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
399742006433	2-enoyl thioester reductase-like; Region: ETR_like; cd05282
399742006434	NADP binding site [chemical binding]; other site
399742006435	dimer interface [polypeptide binding]; other site
399742006436	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
399742006437	Domain of unknown function DUF20; Region: UPF0118; pfam01594
399742006438	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
399742006439	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
399742006440	CHASE4 domain; Region: CHASE4; pfam05228
399742006441	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742006442	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742006443	metal binding site [ion binding]; metal-binding site
399742006444	active site
399742006445	I-site; other site
399742006446	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742006447	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
399742006448	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
399742006449	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
399742006450	active site
399742006451	Zn binding site [ion binding]; other site
399742006452	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742006453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006454	putative substrate translocation pore; other site
399742006455	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
399742006456	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006457	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
399742006458	dimerization interface [polypeptide binding]; other site
399742006459	substrate binding pocket [chemical binding]; other site
399742006460	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
399742006461	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
399742006462	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742006463	nucleotide binding site [chemical binding]; other site
399742006464	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
399742006465	putative dithiobiotin synthetase; Provisional; Region: PRK12374
399742006466	AAA domain; Region: AAA_26; pfam13500
399742006467	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
399742006468	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
399742006469	Walker A/P-loop; other site
399742006470	ATP binding site [chemical binding]; other site
399742006471	Q-loop/lid; other site
399742006472	ABC transporter signature motif; other site
399742006473	Walker B; other site
399742006474	D-loop; other site
399742006475	H-loop/switch region; other site
399742006476	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
399742006477	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006478	dimer interface [polypeptide binding]; other site
399742006479	conserved gate region; other site
399742006480	ABC-ATPase subunit interface; other site
399742006481	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
399742006482	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006483	putative PBP binding loops; other site
399742006484	dimer interface [polypeptide binding]; other site
399742006485	ABC-ATPase subunit interface; other site
399742006486	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
399742006487	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
399742006488	O-methyltransferase; Region: Methyltransf_2; pfam00891
399742006489	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
399742006490	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
399742006491	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742006492	Coenzyme A binding pocket [chemical binding]; other site
399742006493	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
399742006494	hypothetical protein; Provisional; Region: PRK13659
399742006495	hypothetical protein; Provisional; Region: PRK02237
399742006496	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
399742006497	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
399742006498	putative active site pocket [active]
399742006499	putative metal binding site [ion binding]; other site
399742006500	putative oxidoreductase; Provisional; Region: PRK10083
399742006501	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
399742006502	putative NAD(P) binding site [chemical binding]; other site
399742006503	catalytic Zn binding site [ion binding]; other site
399742006504	structural Zn binding site [ion binding]; other site
399742006505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006506	metabolite-proton symporter; Region: 2A0106; TIGR00883
399742006507	putative substrate translocation pore; other site
399742006508	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
399742006509	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
399742006510	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
399742006511	YdfZ protein; Region: YdfZ; pfam14001
399742006512	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742006513	Ligand Binding Site [chemical binding]; other site
399742006514	Transcriptional regulators [Transcription]; Region: FadR; COG2186
399742006515	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742006516	DNA-binding site [nucleotide binding]; DNA binding site
399742006517	FCD domain; Region: FCD; pfam07729
399742006518	malonic semialdehyde reductase; Provisional; Region: PRK10538
399742006519	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
399742006520	putative NAD(P) binding site [chemical binding]; other site
399742006521	homodimer interface [polypeptide binding]; other site
399742006522	homotetramer interface [polypeptide binding]; other site
399742006523	active site
399742006524	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
399742006525	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
399742006526	active site
399742006527	Zn binding site [ion binding]; other site
399742006528	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
399742006529	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
399742006530	putative ligand binding site [chemical binding]; other site
399742006531	putative NAD binding site [chemical binding]; other site
399742006532	catalytic site [active]
399742006533	hypothetical protein; Provisional; Region: PRK10695
399742006534	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
399742006535	Protein of unknown function (DUF1318); Region: DUF1318; pfam07027
399742006536	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742006537	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742006538	metal binding site [ion binding]; metal-binding site
399742006539	active site
399742006540	I-site; other site
399742006541	azoreductase; Reviewed; Region: PRK00170
399742006542	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742006543	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
399742006544	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742006545	ATP binding site [chemical binding]; other site
399742006546	putative Mg++ binding site [ion binding]; other site
399742006547	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742006548	nucleotide binding region [chemical binding]; other site
399742006549	ATP-binding site [chemical binding]; other site
399742006550	Helicase associated domain (HA2); Region: HA2; pfam04408
399742006551	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
399742006552	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
399742006553	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
399742006554	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
399742006555	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742006556	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742006557	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006558	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742006559	putative substrate translocation pore; other site
399742006560	Uncharacterized conserved protein [Function unknown]; Region: COG1434
399742006561	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
399742006562	putative active site [active]
399742006563	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
399742006564	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
399742006565	NAD binding site [chemical binding]; other site
399742006566	catalytic residues [active]
399742006567	substrate binding site [chemical binding]; other site
399742006568	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
399742006569	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742006570	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
399742006571	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
399742006572	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
399742006573	cytochrome b561; Provisional; Region: PRK11513
399742006574	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
399742006575	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742006576	NAD(P) binding site [chemical binding]; other site
399742006577	active site
399742006578	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006579	metabolite-proton symporter; Region: 2A0106; TIGR00883
399742006580	putative substrate translocation pore; other site
399742006581	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
399742006582	putative metal binding site [ion binding]; other site
399742006583	putative homodimer interface [polypeptide binding]; other site
399742006584	putative homotetramer interface [polypeptide binding]; other site
399742006585	putative homodimer-homodimer interface [polypeptide binding]; other site
399742006586	putative allosteric switch controlling residues; other site
399742006587	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
399742006588	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
399742006589	substrate binding site [chemical binding]; other site
399742006590	catalytic Zn binding site [ion binding]; other site
399742006591	NAD binding site [chemical binding]; other site
399742006592	structural Zn binding site [ion binding]; other site
399742006593	dimer interface [polypeptide binding]; other site
399742006594	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742006595	dimer interface [polypeptide binding]; other site
399742006596	ligand binding site [chemical binding]; other site
399742006597	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742006598	dimerization interface [polypeptide binding]; other site
399742006599	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742006600	dimer interface [polypeptide binding]; other site
399742006601	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
399742006602	putative CheW interface [polypeptide binding]; other site
399742006603	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
399742006604	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006605	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
399742006606	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
399742006607	Trp docking motif [polypeptide binding]; other site
399742006608	putative active site [active]
399742006609	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
399742006610	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006611	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742006612	dimerization interface [polypeptide binding]; other site
399742006613	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
399742006614	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
399742006615	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
399742006616	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
399742006617	substrate binding pocket [chemical binding]; other site
399742006618	catalytic triad [active]
399742006619	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
399742006620	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006621	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742006622	dimerization interface [polypeptide binding]; other site
399742006623	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742006624	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
399742006625	trimer interface [polypeptide binding]; other site
399742006626	eyelet of channel; other site
399742006627	putative aminotransferase; Provisional; Region: PRK12414
399742006628	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742006629	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742006630	homodimer interface [polypeptide binding]; other site
399742006631	catalytic residue [active]
399742006632	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
399742006633	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742006634	substrate binding pocket [chemical binding]; other site
399742006635	membrane-bound complex binding site; other site
399742006636	hinge residues; other site
399742006637	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
399742006638	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
399742006639	ribosomal-protein-L7/L12-serine acetyltransferase; Provisional; Region: PRK10151
399742006640	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
399742006641	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
399742006642	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
399742006643	putative trimer interface [polypeptide binding]; other site
399742006644	putative CoA binding site [chemical binding]; other site
399742006645	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
399742006646	putative trimer interface [polypeptide binding]; other site
399742006647	putative CoA binding site [chemical binding]; other site
399742006648	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
399742006649	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
399742006650	gating phenylalanine in ion channel; other site
399742006651	tellurite resistance protein TehB; Provisional; Region: PRK11207
399742006652	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742006653	S-adenosylmethionine binding site [chemical binding]; other site
399742006654	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
399742006655	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
399742006656	metal binding site [ion binding]; metal-binding site
399742006657	dimer interface [polypeptide binding]; other site
399742006658	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742006659	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
399742006660	peptide binding site [polypeptide binding]; other site
399742006661	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
399742006662	EamA-like transporter family; Region: EamA; pfam00892
399742006663	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
399742006664	EamA-like transporter family; Region: EamA; pfam00892
399742006665	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
399742006666	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006667	benzoate transporter; Region: benE; TIGR00843
399742006668	Benzoate membrane transport protein; Region: BenE; pfam03594
399742006669	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
399742006670	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742006671	non-specific DNA binding site [nucleotide binding]; other site
399742006672	salt bridge; other site
399742006673	sequence-specific DNA binding site [nucleotide binding]; other site
399742006674	Cupin domain; Region: Cupin_2; pfam07883
399742006675	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
399742006676	Peptidase family U32; Region: Peptidase_U32; pfam01136
399742006677	Collagenase; Region: DUF3656; pfam12392
399742006678	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
399742006679	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
399742006680	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
399742006681	conserved cys residue [active]
399742006682	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006683	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006684	Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521
399742006685	active site residue [active]
399742006686	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
399742006687	substrate binding site [chemical binding]; other site
399742006688	THF binding site; other site
399742006689	zinc-binding site [ion binding]; other site
399742006690	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
399742006691	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
399742006692	putative ligand binding site [chemical binding]; other site
399742006693	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
399742006694	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742006695	TM-ABC transporter signature motif; other site
399742006696	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
399742006697	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
399742006698	TM-ABC transporter signature motif; other site
399742006699	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
399742006700	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
399742006701	Walker A/P-loop; other site
399742006702	ATP binding site [chemical binding]; other site
399742006703	Q-loop/lid; other site
399742006704	ABC transporter signature motif; other site
399742006705	Walker B; other site
399742006706	D-loop; other site
399742006707	H-loop/switch region; other site
399742006708	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
399742006709	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
399742006710	Walker A/P-loop; other site
399742006711	ATP binding site [chemical binding]; other site
399742006712	Q-loop/lid; other site
399742006713	ABC transporter signature motif; other site
399742006714	Walker B; other site
399742006715	D-loop; other site
399742006716	H-loop/switch region; other site
399742006717	zinc/cadmium-binding protein; Provisional; Region: PRK10306
399742006718	putative transporter; Provisional; Region: PRK10054
399742006719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006720	putative substrate translocation pore; other site
399742006721	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
399742006722	EamA-like transporter family; Region: EamA; pfam00892
399742006723	EamA-like transporter family; Region: EamA; pfam00892
399742006724	MarB protein; Region: MarB; pfam13999
399742006725	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
399742006726	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006727	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742006728	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
399742006729	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
399742006730	inner membrane protein; Provisional; Region: PRK10995
399742006731	putative arabinose transporter; Provisional; Region: PRK03545
399742006732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006733	putative substrate translocation pore; other site
399742006734	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
399742006735	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
399742006736	tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742006737	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
399742006738	NAD binding site [chemical binding]; other site
399742006739	dimer interface [polypeptide binding]; other site
399742006740	substrate binding site [chemical binding]; other site
399742006741	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
399742006742	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
399742006743	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006744	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
399742006745	putative dimerization interface [polypeptide binding]; other site
399742006746	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
399742006747	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
399742006748	NAD(P) binding site [chemical binding]; other site
399742006749	catalytic residues [active]
399742006750	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
399742006751	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742006752	dimer interface [polypeptide binding]; other site
399742006753	ligand binding site [chemical binding]; other site
399742006754	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742006755	dimerization interface [polypeptide binding]; other site
399742006756	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742006757	dimer interface [polypeptide binding]; other site
399742006758	putative CheW interface [polypeptide binding]; other site
399742006759	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
399742006760	glutaminase; Provisional; Region: PRK00971
399742006761	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
399742006762	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742006763	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742006764	metal binding site [ion binding]; metal-binding site
399742006765	active site
399742006766	I-site; other site
399742006767	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
399742006768	MASE2 domain; Region: MASE2; pfam05230
399742006769	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742006770	metal binding site [ion binding]; metal-binding site
399742006771	active site
399742006772	I-site; other site
399742006773	GAF domain; Region: GAF; pfam01590
399742006774	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
399742006775	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742006776	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742006777	metal binding site [ion binding]; metal-binding site
399742006778	active site
399742006779	I-site; other site
399742006780	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742006781	Coenzyme A binding pocket [chemical binding]; other site
399742006782	altronate oxidoreductase; Provisional; Region: PRK03643
399742006783	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
399742006784	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
399742006785	Predicted membrane protein [Function unknown]; Region: COG3781
399742006786	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
399742006787	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
399742006788	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
399742006789	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742006790	Coenzyme A binding pocket [chemical binding]; other site
399742006791	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
399742006792	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742006793	Coenzyme A binding pocket [chemical binding]; other site
399742006794	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
399742006795	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742006796	S-adenosylmethionine binding site [chemical binding]; other site
399742006797	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
399742006798	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
399742006799	putative substrate binding site [chemical binding]; other site
399742006800	putative ATP binding site [chemical binding]; other site
399742006801	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
399742006802	trimer interface; other site
399742006803	sugar binding site [chemical binding]; other site
399742006804	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
399742006805	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742006806	active site turn [active]
399742006807	phosphorylation site [posttranslational modification]
399742006808	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742006809	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
399742006810	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
399742006811	substrate binding [chemical binding]; other site
399742006812	active site
399742006813	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
399742006814	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
399742006815	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742006816	DNA binding site [nucleotide binding]
399742006817	domain linker motif; other site
399742006818	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
399742006819	dimerization interface [polypeptide binding]; other site
399742006820	ligand binding site [chemical binding]; other site
399742006821	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742006822	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006823	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
399742006824	putative dimerization interface [polypeptide binding]; other site
399742006825	putative substrate binding pocket [chemical binding]; other site
399742006826	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
399742006827	acetolactate synthase; Reviewed; Region: PRK08617
399742006828	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
399742006829	PYR/PP interface [polypeptide binding]; other site
399742006830	dimer interface [polypeptide binding]; other site
399742006831	TPP binding site [chemical binding]; other site
399742006832	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
399742006833	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
399742006834	TPP-binding site [chemical binding]; other site
399742006835	dimer interface [polypeptide binding]; other site
399742006836	acetoin reductase; Validated; Region: PRK08643
399742006837	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
399742006838	NAD binding site [chemical binding]; other site
399742006839	homotetramer interface [polypeptide binding]; other site
399742006840	homodimer interface [polypeptide binding]; other site
399742006841	active site
399742006842	substrate binding site [chemical binding]; other site
399742006843	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
399742006844	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
399742006845	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
399742006846	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
399742006847	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
399742006848	dimerization domain [polypeptide binding]; other site
399742006849	dimer interface [polypeptide binding]; other site
399742006850	catalytic residues [active]
399742006851	Sensors of blue-light using FAD; Region: BLUF; smart01034
399742006852	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742006853	HipA N-terminal domain; Region: Couple_hipA; pfam13657
399742006854	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
399742006855	HipA-like N-terminal domain; Region: HipA_N; pfam07805
399742006856	HipA-like C-terminal domain; Region: HipA_C; pfam07804
399742006857	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
399742006858	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742006859	non-specific DNA binding site [nucleotide binding]; other site
399742006860	salt bridge; other site
399742006861	sequence-specific DNA binding site [nucleotide binding]; other site
399742006862	Predicted transcriptional regulators [Transcription]; Region: COG1733
399742006863	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
399742006864	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742006865	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006866	putative substrate translocation pore; other site
399742006867	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
399742006868	poly(beta-D-mannuronate) lyase; Provisional; Region: algL; PRK00325
399742006869	active site
399742006870	short chain dehydrogenase; Provisional; Region: PRK06500
399742006871	classical (c) SDRs; Region: SDR_c; cd05233
399742006872	NAD(P) binding site [chemical binding]; other site
399742006873	active site
399742006874	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742006875	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006876	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
399742006877	putative effector binding pocket; other site
399742006878	putative dimerization interface [polypeptide binding]; other site
399742006879	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
399742006880	transcriptional regulator; Provisional; Region: PRK10632
399742006881	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742006882	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742006883	putative effector binding pocket; other site
399742006884	dimerization interface [polypeptide binding]; other site
399742006885	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
399742006886	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742006887	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
399742006888	active site
399742006889	metal binding site [ion binding]; metal-binding site
399742006890	biofilm-dependent modulation protein; Provisional; Region: PRK11436
399742006891	30S ribosomal protein subunit S22 family; Region: Ribosomal_S22; pfam08136
399742006892	malate dehydrogenase; Provisional; Region: PRK13529
399742006893	Malic enzyme, N-terminal domain; Region: malic; pfam00390
399742006894	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
399742006895	NAD(P) binding site [chemical binding]; other site
399742006896	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
399742006897	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742006898	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742006899	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
399742006900	dimer interface [polypeptide binding]; other site
399742006901	substrate binding site [chemical binding]; other site
399742006902	metal binding sites [ion binding]; metal-binding site
399742006903	MFS transport protein AraJ; Provisional; Region: PRK10091
399742006904	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006905	putative substrate translocation pore; other site
399742006906	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
399742006907	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
399742006908	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
399742006909	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
399742006910	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
399742006911	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742006912	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742006913	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
399742006914	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
399742006915	molybdopterin cofactor binding site; other site
399742006916	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742006917	aromatic amino acid exporter; Provisional; Region: PRK11689
399742006918	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742006919	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
399742006920	trimer interface [polypeptide binding]; other site
399742006921	eyelet of channel; other site
399742006922	Uncharacterized conserved protein [Function unknown]; Region: COG3791
399742006923	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
399742006924	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742006925	TetR family transcriptional regulator; Provisional; Region: PRK14996
399742006926	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742006927	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
399742006928	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
399742006929	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
399742006930	[4Fe-4S] binding site [ion binding]; other site
399742006931	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742006932	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742006933	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742006934	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
399742006935	molybdopterin cofactor binding site; other site
399742006936	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
399742006937	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
399742006938	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
399742006939	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
399742006940	toxin MazF; Provisional; Region: PRK09907
399742006941	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
399742006942	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
399742006943	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742006944	dimer interface [polypeptide binding]; other site
399742006945	conserved gate region; other site
399742006946	putative PBP binding loops; other site
399742006947	ABC-ATPase subunit interface; other site
399742006948	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
399742006949	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
399742006950	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
399742006951	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
399742006952	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
399742006953	Walker A/P-loop; other site
399742006954	ATP binding site [chemical binding]; other site
399742006955	Q-loop/lid; other site
399742006956	ABC transporter signature motif; other site
399742006957	Walker B; other site
399742006958	D-loop; other site
399742006959	H-loop/switch region; other site
399742006960	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
399742006961	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
399742006962	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
399742006963	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
399742006964	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
399742006965	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
399742006966	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
399742006967	putative active site [active]
399742006968	putative catalytic site [active]
399742006969	putative Zn binding site [ion binding]; other site
399742006970	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
399742006971	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
399742006972	active site
399742006973	substrate binding site [chemical binding]; other site
399742006974	cosubstrate binding site; other site
399742006975	catalytic site [active]
399742006976	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
399742006977	active site
399742006978	hexamer interface [polypeptide binding]; other site
399742006979	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
399742006980	NAD binding site [chemical binding]; other site
399742006981	substrate binding site [chemical binding]; other site
399742006982	active site
399742006983	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
399742006984	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
399742006985	Ligand binding site; other site
399742006986	Putative Catalytic site; other site
399742006987	DXD motif; other site
399742006988	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
399742006989	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
399742006990	inhibitor-cofactor binding pocket; inhibition site
399742006991	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742006992	catalytic residue [active]
399742006993	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
399742006994	elongation factor G; Reviewed; Region: PRK00007
399742006995	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
399742006996	G1 box; other site
399742006997	putative GEF interaction site [polypeptide binding]; other site
399742006998	GTP/Mg2+ binding site [chemical binding]; other site
399742006999	Switch I region; other site
399742007000	G2 box; other site
399742007001	G3 box; other site
399742007002	Switch II region; other site
399742007003	G4 box; other site
399742007004	G5 box; other site
399742007005	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
399742007006	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
399742007007	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
399742007008	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742007009	dimerization interface [polypeptide binding]; other site
399742007010	putative DNA binding site [nucleotide binding]; other site
399742007011	putative Zn2+ binding site [ion binding]; other site
399742007012	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
399742007013	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742007014	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
399742007015	substrate binding pocket [chemical binding]; other site
399742007016	membrane-bound complex binding site; other site
399742007017	hinge residues; other site
399742007018	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
399742007019	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742007020	Walker A/P-loop; other site
399742007021	ATP binding site [chemical binding]; other site
399742007022	Q-loop/lid; other site
399742007023	ABC transporter signature motif; other site
399742007024	Walker B; other site
399742007025	D-loop; other site
399742007026	H-loop/switch region; other site
399742007027	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742007028	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007029	dimer interface [polypeptide binding]; other site
399742007030	conserved gate region; other site
399742007031	putative PBP binding loops; other site
399742007032	ABC-ATPase subunit interface; other site
399742007033	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742007034	Coenzyme A binding pocket [chemical binding]; other site
399742007035	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742007036	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
399742007037	substrate binding pocket [chemical binding]; other site
399742007038	membrane-bound complex binding site; other site
399742007039	hinge residues; other site
399742007040	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
399742007041	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
399742007042	active site
399742007043	non-prolyl cis peptide bond; other site
399742007044	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
399742007045	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
399742007046	metal binding site [ion binding]; metal-binding site
399742007047	dimer interface [polypeptide binding]; other site
399742007048	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
399742007049	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
399742007050	AAA domain; Region: AAA_17; pfam13207
399742007051	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742007052	PAS domain; Region: PAS_9; pfam13426
399742007053	putative active site [active]
399742007054	heme pocket [chemical binding]; other site
399742007055	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
399742007056	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742007057	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742007058	dimer interface [polypeptide binding]; other site
399742007059	putative CheW interface [polypeptide binding]; other site
399742007060	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
399742007061	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742007062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742007063	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
399742007064	putative effector binding pocket; other site
399742007065	putative dimerization interface [polypeptide binding]; other site
399742007066	L-asparagine permease; Provisional; Region: PRK15049
399742007067	PQQ-like domain; Region: PQQ_2; pfam13360
399742007068	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
399742007069	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
399742007070	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742007071	N-terminal plug; other site
399742007072	ligand-binding site [chemical binding]; other site
399742007073	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
399742007074	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742007075	dimerization interface [polypeptide binding]; other site
399742007076	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742007077	dimer interface [polypeptide binding]; other site
399742007078	putative CheW interface [polypeptide binding]; other site
399742007079	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
399742007080	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742007081	DNA-binding site [nucleotide binding]; DNA binding site
399742007082	FCD domain; Region: FCD; pfam07729
399742007083	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
399742007084	Prostaglandin dehydrogenases; Region: PGDH; cd05288
399742007085	NAD(P) binding site [chemical binding]; other site
399742007086	substrate binding site [chemical binding]; other site
399742007087	dimer interface [polypeptide binding]; other site
399742007088	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
399742007089	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742007090	non-specific DNA binding site [nucleotide binding]; other site
399742007091	salt bridge; other site
399742007092	sequence-specific DNA binding site [nucleotide binding]; other site
399742007093	Cupin domain; Region: Cupin_2; pfam07883
399742007094	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
399742007095	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742007096	Coenzyme A binding pocket [chemical binding]; other site
399742007097	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
399742007098	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
399742007099	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742007100	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
399742007101	peptide binding site [polypeptide binding]; other site
399742007102	Virulence factor SrfB; Region: SrfB; pfam07520
399742007103	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
399742007104	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
399742007105	homotrimer interaction site [polypeptide binding]; other site
399742007106	putative active site [active]
399742007107	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
399742007108	methionine synthase; Provisional; Region: PRK01207
399742007109	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
399742007110	substrate binding site [chemical binding]; other site
399742007111	THF binding site; other site
399742007112	zinc-binding site [ion binding]; other site
399742007113	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
399742007114	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
399742007115	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
399742007116	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742007117	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742007118	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742007119	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
399742007120	putative effector binding pocket; other site
399742007121	putative dimerization interface [polypeptide binding]; other site
399742007122	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
399742007123	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
399742007124	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742007125	dimerization interface [polypeptide binding]; other site
399742007126	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742007127	dimer interface [polypeptide binding]; other site
399742007128	putative CheW interface [polypeptide binding]; other site
399742007129	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
399742007130	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
399742007131	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
399742007132	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
399742007133	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
399742007134	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
399742007135	tetrameric interface [polypeptide binding]; other site
399742007136	NAD binding site [chemical binding]; other site
399742007137	catalytic residues [active]
399742007138	substrate binding site [chemical binding]; other site
399742007139	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
399742007140	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
399742007141	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007142	dimer interface [polypeptide binding]; other site
399742007143	conserved gate region; other site
399742007144	putative PBP binding loops; other site
399742007145	ABC-ATPase subunit interface; other site
399742007146	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
399742007147	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742007148	Walker A/P-loop; other site
399742007149	ATP binding site [chemical binding]; other site
399742007150	Q-loop/lid; other site
399742007151	ABC transporter signature motif; other site
399742007152	Walker B; other site
399742007153	D-loop; other site
399742007154	H-loop/switch region; other site
399742007155	TOBE domain; Region: TOBE_2; pfam08402
399742007156	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
399742007157	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
399742007158	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
399742007159	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742007160	DNA-binding site [nucleotide binding]; DNA binding site
399742007161	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742007162	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742007163	homodimer interface [polypeptide binding]; other site
399742007164	catalytic residue [active]
399742007165	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
399742007166	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
399742007167	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
399742007168	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
399742007169	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
399742007170	heat-inducible protein; Provisional; Region: PRK10449
399742007171	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
399742007172	Domain of unknown function (DUF333); Region: DUF333; pfam03891
399742007173	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
399742007174	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
399742007175	dimer interface [polypeptide binding]; other site
399742007176	PYR/PP interface [polypeptide binding]; other site
399742007177	TPP binding site [chemical binding]; other site
399742007178	substrate binding site [chemical binding]; other site
399742007179	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
399742007180	Domain of unknown function; Region: EKR; pfam10371
399742007181	4Fe-4S binding domain; Region: Fer4_6; pfam12837
399742007182	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
399742007183	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
399742007184	TPP-binding site [chemical binding]; other site
399742007185	dimer interface [polypeptide binding]; other site
399742007186	KTSC domain; Region: KTSC; pfam13619
399742007187	Uncharacterized conserved protein [Function unknown]; Region: COG3791
399742007188	Tar ligand binding domain homologue; Region: TarH; pfam02203
399742007189	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742007190	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742007191	dimer interface [polypeptide binding]; other site
399742007192	putative CheW interface [polypeptide binding]; other site
399742007193	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
399742007194	GAF domain; Region: GAF; pfam01590
399742007195	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742007196	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742007197	metal binding site [ion binding]; metal-binding site
399742007198	active site
399742007199	I-site; other site
399742007200	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
399742007201	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
399742007202	DNA binding site [nucleotide binding]
399742007203	active site
399742007204	Int/Topo IB signature motif; other site
399742007205	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
399742007206	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
399742007207	Ligand Binding Site [chemical binding]; other site
399742007208	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
399742007209	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
399742007210	ATP binding site [chemical binding]; other site
399742007211	Mg++ binding site [ion binding]; other site
399742007212	motif III; other site
399742007213	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742007214	nucleotide binding region [chemical binding]; other site
399742007215	ATP-binding site [chemical binding]; other site
399742007216	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
399742007217	putative RNA binding site [nucleotide binding]; other site
399742007218	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
399742007219	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
399742007220	Cl binding site [ion binding]; other site
399742007221	oligomer interface [polypeptide binding]; other site
399742007222	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742007223	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742007224	dimer interface [polypeptide binding]; other site
399742007225	putative CheW interface [polypeptide binding]; other site
399742007226	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
399742007227	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
399742007228	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
399742007229	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742007230	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742007231	metal binding site [ion binding]; metal-binding site
399742007232	active site
399742007233	I-site; other site
399742007234	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742007235	PAS domain S-box; Region: sensory_box; TIGR00229
399742007236	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742007237	putative active site [active]
399742007238	heme pocket [chemical binding]; other site
399742007239	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742007240	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742007241	metal binding site [ion binding]; metal-binding site
399742007242	active site
399742007243	I-site; other site
399742007244	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
399742007245	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
399742007246	peptide binding site [polypeptide binding]; other site
399742007247	murein peptide amidase A; Provisional; Region: PRK10602
399742007248	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
399742007249	active site
399742007250	Zn binding site [ion binding]; other site
399742007251	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
399742007252	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
399742007253	active site
399742007254	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
399742007255	dimer interface [polypeptide binding]; other site
399742007256	catalytic triad [active]
399742007257	peroxidatic and resolving cysteines [active]
399742007258	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
399742007259	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
399742007260	PAS domain; Region: PAS; smart00091
399742007261	putative active site [active]
399742007262	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742007263	Walker A motif; other site
399742007264	ATP binding site [chemical binding]; other site
399742007265	Walker B motif; other site
399742007266	arginine finger; other site
399742007267	hypothetical protein; Provisional; Region: PRK05415
399742007268	Domain of unknown function (DUF697); Region: DUF697; cl12064
399742007269	Predicted ATPase [General function prediction only]; Region: COG3106
399742007270	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742007271	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742007272	DNA binding site [nucleotide binding]
399742007273	domain linker motif; other site
399742007274	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
399742007275	putative dimerization interface [polypeptide binding]; other site
399742007276	putative ligand binding site [chemical binding]; other site
399742007277	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
399742007278	beta-phosphoglucomutase; Region: bPGM; TIGR01990
399742007279	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742007280	motif II; other site
399742007281	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
399742007282	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
399742007283	Walker A/P-loop; other site
399742007284	ATP binding site [chemical binding]; other site
399742007285	Q-loop/lid; other site
399742007286	ABC transporter signature motif; other site
399742007287	Walker B; other site
399742007288	D-loop; other site
399742007289	H-loop/switch region; other site
399742007290	TOBE domain; Region: TOBE_2; pfam08402
399742007291	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
399742007292	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
399742007293	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
399742007294	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
399742007295	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
399742007296	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
399742007297	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
399742007298	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
399742007299	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
399742007300	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
399742007301	putative NAD(P) binding site [chemical binding]; other site
399742007302	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
399742007303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007304	dimer interface [polypeptide binding]; other site
399742007305	conserved gate region; other site
399742007306	putative PBP binding loops; other site
399742007307	ABC-ATPase subunit interface; other site
399742007308	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007309	dimer interface [polypeptide binding]; other site
399742007310	conserved gate region; other site
399742007311	putative PBP binding loops; other site
399742007312	ABC-ATPase subunit interface; other site
399742007313	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
399742007314	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
399742007315	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
399742007316	sucrose phosphorylase; Provisional; Region: PRK13840
399742007317	active site
399742007318	homodimer interface [polypeptide binding]; other site
399742007319	catalytic site [active]
399742007320	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
399742007321	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
399742007322	phage shock protein C; Region: phageshock_pspC; TIGR02978
399742007323	phage shock protein B; Provisional; Region: pspB; PRK09458
399742007324	phage shock protein PspA; Provisional; Region: PRK10698
399742007325	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
399742007326	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742007327	Walker A motif; other site
399742007328	ATP binding site [chemical binding]; other site
399742007329	Walker B motif; other site
399742007330	arginine finger; other site
399742007331	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
399742007332	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
399742007333	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
399742007334	peptide binding site [polypeptide binding]; other site
399742007335	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
399742007336	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007337	dimer interface [polypeptide binding]; other site
399742007338	conserved gate region; other site
399742007339	putative PBP binding loops; other site
399742007340	ABC-ATPase subunit interface; other site
399742007341	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
399742007342	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
399742007343	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007344	dimer interface [polypeptide binding]; other site
399742007345	conserved gate region; other site
399742007346	putative PBP binding loops; other site
399742007347	ABC-ATPase subunit interface; other site
399742007348	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
399742007349	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742007350	Walker A/P-loop; other site
399742007351	ATP binding site [chemical binding]; other site
399742007352	Q-loop/lid; other site
399742007353	ABC transporter signature motif; other site
399742007354	Walker B; other site
399742007355	D-loop; other site
399742007356	H-loop/switch region; other site
399742007357	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
399742007358	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
399742007359	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742007360	Walker A/P-loop; other site
399742007361	ATP binding site [chemical binding]; other site
399742007362	Q-loop/lid; other site
399742007363	ABC transporter signature motif; other site
399742007364	Walker B; other site
399742007365	D-loop; other site
399742007366	H-loop/switch region; other site
399742007367	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
399742007368	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
399742007369	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
399742007370	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
399742007371	NAD binding site [chemical binding]; other site
399742007372	homotetramer interface [polypeptide binding]; other site
399742007373	homodimer interface [polypeptide binding]; other site
399742007374	substrate binding site [chemical binding]; other site
399742007375	active site
399742007376	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
399742007377	exoribonuclease II; Provisional; Region: PRK05054
399742007378	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
399742007379	RNB domain; Region: RNB; pfam00773
399742007380	S1 RNA binding domain; Region: S1; pfam00575
399742007381	RNase II stability modulator; Provisional; Region: PRK10060
399742007382	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742007383	putative active site [active]
399742007384	heme pocket [chemical binding]; other site
399742007385	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742007386	metal binding site [ion binding]; metal-binding site
399742007387	active site
399742007388	I-site; other site
399742007389	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742007390	enoyl-CoA hydratase; Validated; Region: PRK08788
399742007391	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
399742007392	substrate binding site [chemical binding]; other site
399742007393	oxyanion hole (OAH) forming residues; other site
399742007394	trimer interface [polypeptide binding]; other site
399742007395	hypothetical protein; Provisional; Region: PRK13658
399742007396	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
399742007397	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
399742007398	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
399742007399	lipoprotein; Provisional; Region: PRK10540
399742007400	translation initiation factor Sui1; Validated; Region: PRK06824
399742007401	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
399742007402	putative rRNA binding site [nucleotide binding]; other site
399742007403	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
399742007404	active site
399742007405	dimer interface [polypeptide binding]; other site
399742007406	tetratricopeptide repeat protein; Provisional; Region: PRK11788
399742007407	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742007408	binding surface
399742007409	TPR motif; other site
399742007410	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
399742007411	binding surface
399742007412	TPR motif; other site
399742007413	Predicted membrane protein [Function unknown]; Region: COG3771
399742007414	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
399742007415	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
399742007416	active site
399742007417	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
399742007418	dimerization interface [polypeptide binding]; other site
399742007419	active site
399742007420	aconitate hydratase; Validated; Region: PRK09277
399742007421	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
399742007422	substrate binding site [chemical binding]; other site
399742007423	ligand binding site [chemical binding]; other site
399742007424	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
399742007425	substrate binding site [chemical binding]; other site
399742007426	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
399742007427	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742007428	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
399742007429	substrate binding site [chemical binding]; other site
399742007430	putative dimerization interface [polypeptide binding]; other site
399742007431	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
399742007432	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
399742007433	active site
399742007434	interdomain interaction site; other site
399742007435	putative metal-binding site [ion binding]; other site
399742007436	nucleotide binding site [chemical binding]; other site
399742007437	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
399742007438	domain I; other site
399742007439	DNA binding groove [nucleotide binding]
399742007440	phosphate binding site [ion binding]; other site
399742007441	domain II; other site
399742007442	domain III; other site
399742007443	nucleotide binding site [chemical binding]; other site
399742007444	catalytic site [active]
399742007445	domain IV; other site
399742007446	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
399742007447	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
399742007448	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
399742007449	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
399742007450	hypothetical protein; Provisional; Region: PRK11037
399742007451	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
399742007452	putative inner membrane peptidase; Provisional; Region: PRK11778
399742007453	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
399742007454	tandem repeat interface [polypeptide binding]; other site
399742007455	oligomer interface [polypeptide binding]; other site
399742007456	active site residues [active]
399742007457	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
399742007458	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
399742007459	NADP binding site [chemical binding]; other site
399742007460	homodimer interface [polypeptide binding]; other site
399742007461	active site
399742007462	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
399742007463	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
399742007464	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
399742007465	homodimer interface [polypeptide binding]; other site
399742007466	Walker A motif; other site
399742007467	ATP binding site [chemical binding]; other site
399742007468	hydroxycobalamin binding site [chemical binding]; other site
399742007469	Walker B motif; other site
399742007470	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
399742007471	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742007472	RNA binding surface [nucleotide binding]; other site
399742007473	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
399742007474	probable active site [active]
399742007475	hypothetical protein; Provisional; Region: PRK11630
399742007476	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
399742007477	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
399742007478	active site
399742007479	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
399742007480	anthranilate synthase component I; Provisional; Region: PRK13564
399742007481	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
399742007482	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
399742007483	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
399742007484	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
399742007485	glutamine binding [chemical binding]; other site
399742007486	catalytic triad [active]
399742007487	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
399742007488	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
399742007489	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
399742007490	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
399742007491	active site
399742007492	ribulose/triose binding site [chemical binding]; other site
399742007493	phosphate binding site [ion binding]; other site
399742007494	substrate (anthranilate) binding pocket [chemical binding]; other site
399742007495	product (indole) binding pocket [chemical binding]; other site
399742007496	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
399742007497	active site
399742007498	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
399742007499	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
399742007500	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742007501	catalytic residue [active]
399742007502	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
399742007503	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
399742007504	substrate binding site [chemical binding]; other site
399742007505	active site
399742007506	catalytic residues [active]
399742007507	heterodimer interface [polypeptide binding]; other site
399742007508	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
399742007509	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
399742007510	SEC-C motif; Region: SEC-C; pfam02810
399742007511	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
399742007512	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
399742007513	active site
399742007514	DNA binding site [nucleotide binding]
399742007515	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
399742007516	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
399742007517	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742007518	Catalytic site [active]
399742007519	Colicin pore forming domain; Region: Colicin; pfam01024
399742007520	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
399742007521	Phage-related protein, tail component [Function unknown]; Region: COG4733
399742007522	Putative phage tail protein; Region: Phage-tail_3; pfam13550
399742007523	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
399742007524	Interdomain contacts; other site
399742007525	Cytokine receptor motif; other site
399742007526	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
399742007527	Phage-related protein, tail component [Function unknown]; Region: COG4723
399742007528	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
399742007529	MPN+ (JAMM) motif; other site
399742007530	Zinc-binding site [ion binding]; other site
399742007531	NlpC/P60 family; Region: NLPC_P60; pfam00877
399742007532	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
399742007533	Phage minor tail protein L; Region: Phage_tail_L; cl01908
399742007534	Phage minor tail protein; Region: Phage_min_tail; pfam05939
399742007535	Phage-related minor tail protein [Function unknown]; Region: COG5281
399742007536	tape measure domain; Region: tape_meas_nterm; TIGR02675
399742007537	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
399742007538	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
399742007539	Protein of unknown function (DUF1635); Region: DUF1635; pfam07795
399742007540	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
399742007541	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
399742007542	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
399742007543	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
399742007544	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
399742007545	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
399742007546	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
399742007547	oligomerization interface [polypeptide binding]; other site
399742007548	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
399742007549	Phage-related protein [Function unknown]; Region: COG4695
399742007550	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
399742007551	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
399742007552	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
399742007553	Phage capsid family; Region: Phage_capsid; pfam05065
399742007554	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
399742007555	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
399742007556	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
399742007557	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
399742007558	active site
399742007559	anti-RssB factor; Provisional; Region: PRK10244
399742007560	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
399742007561	active site
399742007562	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
399742007563	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
399742007564	catalytic residues [active]
399742007565	Lysis protein S; Region: Lysis_S; pfam04971
399742007566	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742007567	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
399742007568	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
399742007569	DNA methylase; Region: N6_N4_Mtase; pfam01555
399742007570	Protein of unknown function (DUF968); Region: DUF968; pfam06147
399742007571	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
399742007572	DinI-like family; Region: DinI; cl11630
399742007573	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; cl11635
399742007574	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
399742007575	Pyocin large subunit [General function prediction only]; Region: COG5529
399742007576	primosomal protein DnaI; Provisional; Region: PRK02854
399742007577	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
399742007578	transcriptional repressor DicA; Reviewed; Region: PRK09706
399742007579	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742007580	non-specific DNA binding site [nucleotide binding]; other site
399742007581	salt bridge; other site
399742007582	sequence-specific DNA binding site [nucleotide binding]; other site
399742007583	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
399742007584	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
399742007585	active site
399742007586	catalytic site [active]
399742007587	substrate binding site [chemical binding]; other site
399742007588	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
399742007589	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
399742007590	dimer interface [polypeptide binding]; other site
399742007591	active site
399742007592	Int/Topo IB signature motif; other site
399742007593	putative inner membrane protein; Provisional; Region: PRK11099
399742007594	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
399742007595	CPxP  motif; other site
399742007596	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
399742007597	active site
399742007598	P-loop; other site
399742007599	phosphorylation site [posttranslational modification]
399742007600	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742007601	Coenzyme A binding pocket [chemical binding]; other site
399742007602	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
399742007603	active site residue [active]
399742007604	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
399742007605	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742007606	putative Zn2+ binding site [ion binding]; other site
399742007607	putative DNA binding site [nucleotide binding]; other site
399742007608	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742007609	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742007610	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
399742007611	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
399742007612	FMN binding site [chemical binding]; other site
399742007613	active site
399742007614	substrate binding site [chemical binding]; other site
399742007615	catalytic residue [active]
399742007616	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
399742007617	classical (c) SDRs; Region: SDR_c; cd05233
399742007618	NAD(P) binding site [chemical binding]; other site
399742007619	active site
399742007620	short chain dehydrogenase; Provisional; Region: PRK06179
399742007621	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
399742007622	NADP binding site [chemical binding]; other site
399742007623	active site
399742007624	steroid binding site; other site
399742007625	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
399742007626	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
399742007627	putative NAD(P) binding site [chemical binding]; other site
399742007628	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
399742007629	outer membrane protein W; Provisional; Region: PRK10959
399742007630	hypothetical protein; Provisional; Region: PRK02868
399742007631	intracellular septation protein A; Reviewed; Region: PRK00259
399742007632	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
399742007633	transport protein TonB; Provisional; Region: PRK10819
399742007634	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
399742007635	YciI-like protein; Reviewed; Region: PRK11370
399742007636	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
399742007637	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
399742007638	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
399742007639	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
399742007640	EamA-like transporter family; Region: EamA; cl17759
399742007641	EamA-like transporter family; Region: EamA; pfam00892
399742007642	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
399742007643	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742007644	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
399742007645	dimerization interface [polypeptide binding]; other site
399742007646	substrate binding pocket [chemical binding]; other site
399742007647	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
399742007648	leucine export protein LeuE; Provisional; Region: PRK10958
399742007649	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
399742007650	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
399742007651	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
399742007652	putative active site [active]
399742007653	catalytic site [active]
399742007654	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
399742007655	putative active site [active]
399742007656	catalytic site [active]
399742007657	dsDNA-mimic protein; Reviewed; Region: PRK05094
399742007658	Ion transport protein; Region: Ion_trans; pfam00520
399742007659	Ion channel; Region: Ion_trans_2; pfam07885
399742007660	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
399742007661	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742007662	Walker A/P-loop; other site
399742007663	ATP binding site [chemical binding]; other site
399742007664	Q-loop/lid; other site
399742007665	ABC transporter signature motif; other site
399742007666	Walker B; other site
399742007667	D-loop; other site
399742007668	H-loop/switch region; other site
399742007669	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
399742007670	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
399742007671	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742007672	Walker A/P-loop; other site
399742007673	ATP binding site [chemical binding]; other site
399742007674	Q-loop/lid; other site
399742007675	ABC transporter signature motif; other site
399742007676	Walker B; other site
399742007677	D-loop; other site
399742007678	H-loop/switch region; other site
399742007679	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
399742007680	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
399742007681	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
399742007682	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007683	dimer interface [polypeptide binding]; other site
399742007684	conserved gate region; other site
399742007685	ABC-ATPase subunit interface; other site
399742007686	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
399742007687	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007688	dimer interface [polypeptide binding]; other site
399742007689	conserved gate region; other site
399742007690	putative PBP binding loops; other site
399742007691	ABC-ATPase subunit interface; other site
399742007692	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
399742007693	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
399742007694	peptide binding site [polypeptide binding]; other site
399742007695	hypothetical protein; Provisional; Region: PRK11111
399742007696	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
399742007697	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
399742007698	putative catalytic cysteine [active]
399742007699	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
399742007700	putative active site [active]
399742007701	metal binding site [ion binding]; metal-binding site
399742007702	thymidine kinase; Provisional; Region: PRK04296
399742007703	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
399742007704	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
399742007705	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
399742007706	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
399742007707	active site
399742007708	tetramer interface; other site
399742007709	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742007710	active site
399742007711	response regulator of RpoS; Provisional; Region: PRK10693
399742007712	phosphorylation site [posttranslational modification]
399742007713	intermolecular recognition site; other site
399742007714	dimerization interface [polypeptide binding]; other site
399742007715	hypothetical protein; Provisional; Region: PRK10279
399742007716	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
399742007717	active site
399742007718	nucleophile elbow; other site
399742007719	SEC-C motif; Region: SEC-C; pfam02810
399742007720	hypothetical protein; Provisional; Region: PRK04233
399742007721	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
399742007722	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
399742007723	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
399742007724	putative active site [active]
399742007725	putative substrate binding site [chemical binding]; other site
399742007726	putative cosubstrate binding site; other site
399742007727	catalytic site [active]
399742007728	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
399742007729	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
399742007730	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
399742007731	4Fe-4S binding domain; Region: Fer4; cl02805
399742007732	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
399742007733	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
399742007734	[4Fe-4S] binding site [ion binding]; other site
399742007735	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742007736	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742007737	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742007738	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
399742007739	molybdopterin cofactor binding site; other site
399742007740	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
399742007741	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
399742007742	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
399742007743	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742007744	dimerization interface [polypeptide binding]; other site
399742007745	Histidine kinase; Region: HisKA_3; pfam07730
399742007746	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742007747	ATP binding site [chemical binding]; other site
399742007748	Mg2+ binding site [ion binding]; other site
399742007749	G-X-G motif; other site
399742007750	transcriptional regulator NarL; Provisional; Region: PRK10651
399742007751	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742007752	active site
399742007753	phosphorylation site [posttranslational modification]
399742007754	intermolecular recognition site; other site
399742007755	dimerization interface [polypeptide binding]; other site
399742007756	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742007757	DNA binding residues [nucleotide binding]
399742007758	dimerization interface [polypeptide binding]; other site
399742007759	putative invasin; Provisional; Region: PRK10177
399742007760	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
399742007761	Helix-turn-helix domain; Region: HTH_28; pfam13518
399742007762	putative transposase OrfB; Reviewed; Region: PHA02517
399742007763	Homeodomain-like domain; Region: HTH_32; pfam13565
399742007764	Integrase core domain; Region: rve; pfam00665
399742007765	Integrase core domain; Region: rve_3; pfam13683
399742007766	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
399742007767	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
399742007768	[4Fe-4S] binding site [ion binding]; other site
399742007769	molybdopterin cofactor binding site; other site
399742007770	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
399742007771	molybdopterin cofactor binding site; other site
399742007772	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
399742007773	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
399742007774	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742007775	nitrite reductase subunit NirD; Provisional; Region: PRK14989
399742007776	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742007777	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
399742007778	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
399742007779	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
399742007780	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
399742007781	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
399742007782	Walker A/P-loop; other site
399742007783	ATP binding site [chemical binding]; other site
399742007784	Q-loop/lid; other site
399742007785	ABC transporter signature motif; other site
399742007786	Walker B; other site
399742007787	D-loop; other site
399742007788	H-loop/switch region; other site
399742007789	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
399742007790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742007791	dimer interface [polypeptide binding]; other site
399742007792	conserved gate region; other site
399742007793	putative PBP binding loops; other site
399742007794	ABC-ATPase subunit interface; other site
399742007795	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
399742007796	NMT1-like family; Region: NMT1_2; pfam13379
399742007797	Nitrate and nitrite sensing; Region: NIT; pfam08376
399742007798	ANTAR domain; Region: ANTAR; pfam03861
399742007799	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
399742007800	Cache domain; Region: Cache_1; pfam02743
399742007801	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742007802	dimerization interface [polypeptide binding]; other site
399742007803	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742007804	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742007805	dimer interface [polypeptide binding]; other site
399742007806	putative CheW interface [polypeptide binding]; other site
399742007807	Domain of unknown function (DUF1883); Region: DUF1883; pfam08980
399742007808	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
399742007809	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
399742007810	putative active site pocket [active]
399742007811	dimerization interface [polypeptide binding]; other site
399742007812	putative catalytic residue [active]
399742007813	cation transport regulator; Reviewed; Region: chaB; PRK09582
399742007814	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
399742007815	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
399742007816	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
399742007817	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
399742007818	hypothetical protein; Provisional; Region: PRK10941
399742007819	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
399742007820	hypothetical protein; Provisional; Region: PRK10278
399742007821	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
399742007822	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
399742007823	peptide chain release factor 1; Validated; Region: prfA; PRK00591
399742007824	This domain is found in peptide chain release factors; Region: PCRF; smart00937
399742007825	RF-1 domain; Region: RF-1; pfam00472
399742007826	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
399742007827	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
399742007828	tRNA; other site
399742007829	putative tRNA binding site [nucleotide binding]; other site
399742007830	putative NADP binding site [chemical binding]; other site
399742007831	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
399742007832	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
399742007833	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
399742007834	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
399742007835	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
399742007836	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
399742007837	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
399742007838	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
399742007839	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742007840	active site
399742007841	putative transporter; Provisional; Region: PRK11660
399742007842	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
399742007843	Sulfate transporter family; Region: Sulfate_transp; pfam00916
399742007844	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
399742007845	hypothetical protein; Provisional; Region: PRK10692
399742007846	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
399742007847	putative active site [active]
399742007848	catalytic residue [active]
399742007849	GTP-binding protein YchF; Reviewed; Region: PRK09601
399742007850	YchF GTPase; Region: YchF; cd01900
399742007851	G1 box; other site
399742007852	GTP/Mg2+ binding site [chemical binding]; other site
399742007853	Switch I region; other site
399742007854	G2 box; other site
399742007855	Switch II region; other site
399742007856	G3 box; other site
399742007857	G4 box; other site
399742007858	G5 box; other site
399742007859	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
399742007860	Cupin domain; Region: Cupin_2; cl17218
399742007861	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
399742007862	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
399742007863	putative molybdopterin cofactor binding site [chemical binding]; other site
399742007864	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
399742007865	putative molybdopterin cofactor binding site; other site
399742007866	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742007867	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742007868	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742007869	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742007870	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
399742007871	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
399742007872	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742007873	membrane-bound complex binding site; other site
399742007874	hinge residues; other site
399742007875	Fatty acid desaturase protein family subgroup, a delta-12 acyl-lipid desaturase-like, DesA-like, yet uncharacterized subgroup of membrane fatty acid desaturase proteins found in alpha-, beta-, and gamma-proteobacteria. Sequences of this domain family...; Region: DesA_FADS-like; cd03509
399742007876	Fatty acid desaturase; Region: FA_desaturase; pfam00487
399742007877	putative di-iron ligands [ion binding]; other site
399742007878	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
399742007879	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742007880	putative substrate translocation pore; other site
399742007881	Cupin; Region: Cupin_6; pfam12852
399742007882	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742007883	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742007884	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742007885	trehalase; Provisional; Region: treA; PRK13271
399742007886	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
399742007887	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
399742007888	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742007889	N-terminal plug; other site
399742007890	ligand-binding site [chemical binding]; other site
399742007891	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
399742007892	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
399742007893	Flagellar regulator YcgR; Region: YcgR; pfam07317
399742007894	PilZ domain; Region: PilZ; pfam07238
399742007895	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
399742007896	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742007897	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742007898	catalytic residue [active]
399742007899	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
399742007900	dimer interface [polypeptide binding]; other site
399742007901	catalytic triad [active]
399742007902	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
399742007903	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
399742007904	TrkA-C domain; Region: TrkA_C; pfam02080
399742007905	Transporter associated domain; Region: CorC_HlyC; smart01091
399742007906	alanine racemase; Reviewed; Region: dadX; PRK03646
399742007907	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
399742007908	active site
399742007909	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
399742007910	substrate binding site [chemical binding]; other site
399742007911	catalytic residues [active]
399742007912	dimer interface [polypeptide binding]; other site
399742007913	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
399742007914	hydroxyglutarate oxidase; Provisional; Region: PRK11728
399742007915	SpoVR family protein; Provisional; Region: PRK11767
399742007916	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
399742007917	fatty acid metabolism regulator; Provisional; Region: PRK04984
399742007918	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742007919	DNA-binding site [nucleotide binding]; DNA binding site
399742007920	FadR C-terminal domain; Region: FadR_C; pfam07840
399742007921	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
399742007922	disulfide bond formation protein B; Provisional; Region: PRK01749
399742007923	hypothetical protein; Provisional; Region: PRK05170
399742007924	hypothetical protein; Provisional; Region: PRK10691
399742007925	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
399742007926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
399742007927	septum formation inhibitor; Reviewed; Region: minC; PRK03511
399742007928	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
399742007929	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
399742007930	cell division inhibitor MinD; Provisional; Region: PRK10818
399742007931	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
399742007932	Switch I; other site
399742007933	Switch II; other site
399742007934	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
399742007935	ribonuclease D; Provisional; Region: PRK10829
399742007936	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
399742007937	catalytic site [active]
399742007938	putative active site [active]
399742007939	putative substrate binding site [chemical binding]; other site
399742007940	Helicase and RNase D C-terminal; Region: HRDC; smart00341
399742007941	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
399742007942	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
399742007943	acyl-activating enzyme (AAE) consensus motif; other site
399742007944	putative AMP binding site [chemical binding]; other site
399742007945	putative active site [active]
399742007946	putative CoA binding site [chemical binding]; other site
399742007947	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
399742007948	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
399742007949	Glycoprotease family; Region: Peptidase_M22; pfam00814
399742007950	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
399742007951	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
399742007952	ATP binding site [chemical binding]; other site
399742007953	DEAD_2; Region: DEAD_2; pfam06733
399742007954	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
399742007955	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
399742007956	homotrimer interaction site [polypeptide binding]; other site
399742007957	putative active site [active]
399742007958	hypothetical protein; Provisional; Region: PRK05114
399742007959	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
399742007960	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
399742007961	chorismate binding enzyme; Region: Chorismate_bind; cl10555
399742007962	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
399742007963	putative active site [active]
399742007964	putative CoA binding site [chemical binding]; other site
399742007965	nudix motif; other site
399742007966	metal binding site [ion binding]; metal-binding site
399742007967	L-serine deaminase; Provisional; Region: PRK15023
399742007968	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
399742007969	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
399742007970	phage resistance protein; Provisional; Region: PRK10551
399742007971	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
399742007972	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742007973	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
399742007974	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
399742007975	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
399742007976	Transporter associated domain; Region: CorC_HlyC; smart01091
399742007977	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
399742007978	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
399742007979	active pocket/dimerization site; other site
399742007980	active site
399742007981	phosphorylation site [posttranslational modification]
399742007982	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
399742007983	active site
399742007984	phosphorylation site [posttranslational modification]
399742007985	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
399742007986	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
399742007987	hypothetical protein; Provisional; Region: PRK02913
399742007988	hypothetical protein; Provisional; Region: PRK11469
399742007989	Domain of unknown function DUF; Region: DUF204; pfam02659
399742007990	Domain of unknown function DUF; Region: DUF204; pfam02659
399742007991	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
399742007992	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742007993	S-adenosylmethionine binding site [chemical binding]; other site
399742007994	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
399742007995	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
399742007996	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
399742007997	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742007998	DNA-binding site [nucleotide binding]; DNA binding site
399742007999	RNA-binding motif; other site
399742008000	YebO-like protein; Region: YebO; pfam13974
399742008001	PhoPQ regulatory protein; Provisional; Region: PRK10299
399742008002	YobH-like protein; Region: YobH; pfam13996
399742008003	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
399742008004	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742008005	dimerization interface [polypeptide binding]; other site
399742008006	putative Zn2+ binding site [ion binding]; other site
399742008007	putative DNA binding site [nucleotide binding]; other site
399742008008	Bacterial transcriptional regulator; Region: IclR; pfam01614
399742008009	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008010	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742008011	putative substrate translocation pore; other site
399742008012	heat shock protein HtpX; Provisional; Region: PRK05457
399742008013	carboxy-terminal protease; Provisional; Region: PRK11186
399742008014	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
399742008015	protein binding site [polypeptide binding]; other site
399742008016	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
399742008017	Catalytic dyad [active]
399742008018	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
399742008019	ProP expression regulator; Provisional; Region: PRK04950
399742008020	ProQ/FINO family; Region: ProQ; pfam04352
399742008021	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
399742008022	GAF domain; Region: GAF_2; pfam13185
399742008023	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
399742008024	Paraquat-inducible protein A; Region: PqiA; pfam04403
399742008025	Paraquat-inducible protein A; Region: PqiA; pfam04403
399742008026	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
399742008027	mce related protein; Region: MCE; pfam02470
399742008028	mce related protein; Region: MCE; pfam02470
399742008029	mce related protein; Region: MCE; pfam02470
399742008030	mce related protein; Region: MCE; pfam02470
399742008031	mce related protein; Region: MCE; pfam02470
399742008032	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
399742008033	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742008034	S-adenosylmethionine binding site [chemical binding]; other site
399742008035	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
399742008036	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
399742008037	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
399742008038	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
399742008039	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
399742008040	active site
399742008041	metal binding site [ion binding]; metal-binding site
399742008042	Protein of unknown function (DUF535); Region: DUF535; pfam04393
399742008043	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
399742008044	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
399742008045	hypothetical protein; Provisional; Region: PRK10301
399742008046	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
399742008047	Predicted amidohydrolase [General function prediction only]; Region: COG0388
399742008048	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
399742008049	exodeoxyribonuclease X; Provisional; Region: PRK07983
399742008050	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
399742008051	active site
399742008052	catalytic site [active]
399742008053	substrate binding site [chemical binding]; other site
399742008054	protease 2; Provisional; Region: PRK10115
399742008055	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742008056	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
399742008057	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
399742008058	putative metal binding site [ion binding]; other site
399742008059	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
399742008060	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
399742008061	ATP-grasp domain; Region: ATP-grasp; pfam02222
399742008062	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
399742008063	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
399742008064	active site
399742008065	intersubunit interface [polypeptide binding]; other site
399742008066	catalytic residue [active]
399742008067	phosphogluconate dehydratase; Validated; Region: PRK09054
399742008068	6-phosphogluconate dehydratase; Region: edd; TIGR01196
399742008069	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
399742008070	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
399742008071	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
399742008072	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
399742008073	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
399742008074	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
399742008075	putative active site [active]
399742008076	pyruvate kinase; Provisional; Region: PRK05826
399742008077	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
399742008078	domain interfaces; other site
399742008079	active site
399742008080	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
399742008081	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
399742008082	putative acyl-acceptor binding pocket; other site
399742008083	putative peptidase; Provisional; Region: PRK11649
399742008084	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
399742008085	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
399742008086	Peptidase family M23; Region: Peptidase_M23; pfam01551
399742008087	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
399742008088	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
399742008089	metal binding site [ion binding]; metal-binding site
399742008090	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
399742008091	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
399742008092	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
399742008093	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742008094	ABC-ATPase subunit  interface; other site
399742008095	dimer interface [polypeptide binding]; other site
399742008096	putative PBP binding regions; other site
399742008097	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
399742008098	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742008099	Walker A motif; other site
399742008100	ATP binding site [chemical binding]; other site
399742008101	Walker B motif; other site
399742008102	arginine finger; other site
399742008103	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
399742008104	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
399742008105	RuvA N terminal domain; Region: RuvA_N; pfam01330
399742008106	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
399742008107	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
399742008108	active site
399742008109	putative DNA-binding cleft [nucleotide binding]; other site
399742008110	dimer interface [polypeptide binding]; other site
399742008111	hypothetical protein; Validated; Region: PRK00110
399742008112	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
399742008113	nudix motif; other site
399742008114	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
399742008115	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
399742008116	dimer interface [polypeptide binding]; other site
399742008117	anticodon binding site; other site
399742008118	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
399742008119	homodimer interface [polypeptide binding]; other site
399742008120	motif 1; other site
399742008121	active site
399742008122	motif 2; other site
399742008123	GAD domain; Region: GAD; pfam02938
399742008124	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
399742008125	active site
399742008126	motif 3; other site
399742008127	Isochorismatase family; Region: Isochorismatase; pfam00857
399742008128	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
399742008129	catalytic triad [active]
399742008130	conserved cis-peptide bond; other site
399742008131	hypothetical protein; Provisional; Region: PRK10302
399742008132	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
399742008133	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742008134	S-adenosylmethionine binding site [chemical binding]; other site
399742008135	Methyltransferase domain; Region: Methyltransf_23; pfam13489
399742008136	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742008137	S-adenosylmethionine binding site [chemical binding]; other site
399742008138	copper homeostasis protein CutC; Provisional; Region: PRK11572
399742008139	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
399742008140	putative metal binding site [ion binding]; other site
399742008141	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
399742008142	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
399742008143	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
399742008144	active site
399742008145	HIGH motif; other site
399742008146	KMSK motif region; other site
399742008147	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
399742008148	tRNA binding surface [nucleotide binding]; other site
399742008149	anticodon binding site; other site
399742008150	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
399742008151	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
399742008152	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008153	Flagellar protein FlhE; Region: FlhE; pfam06366
399742008154	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
399742008155	FHIPEP family; Region: FHIPEP; pfam00771
399742008156	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
399742008157	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
399742008158	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742008159	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
399742008160	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
399742008161	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
399742008162	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
399742008163	PapC N-terminal domain; Region: PapC_N; pfam13954
399742008164	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
399742008165	PapC C-terminal domain; Region: PapC_C; pfam13953
399742008166	Fimbrial protein; Region: Fimbrial; pfam00419
399742008167	chemotaxis regulator CheZ; Provisional; Region: PRK11166
399742008168	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
399742008169	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742008170	active site
399742008171	phosphorylation site [posttranslational modification]
399742008172	intermolecular recognition site; other site
399742008173	dimerization interface [polypeptide binding]; other site
399742008174	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
399742008175	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742008176	active site
399742008177	phosphorylation site [posttranslational modification]
399742008178	intermolecular recognition site; other site
399742008179	dimerization interface [polypeptide binding]; other site
399742008180	CheB methylesterase; Region: CheB_methylest; pfam01339
399742008181	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
399742008182	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
399742008183	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742008184	S-adenosylmethionine binding site [chemical binding]; other site
399742008185	methyl-accepting protein IV; Provisional; Region: PRK09793
399742008186	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742008187	dimer interface [polypeptide binding]; other site
399742008188	ligand binding site [chemical binding]; other site
399742008189	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742008190	dimerization interface [polypeptide binding]; other site
399742008191	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742008192	dimer interface [polypeptide binding]; other site
399742008193	putative CheW interface [polypeptide binding]; other site
399742008194	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
399742008195	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
399742008196	dimer interface [polypeptide binding]; other site
399742008197	ligand binding site [chemical binding]; other site
399742008198	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742008199	dimerization interface [polypeptide binding]; other site
399742008200	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742008201	dimer interface [polypeptide binding]; other site
399742008202	putative CheW interface [polypeptide binding]; other site
399742008203	Spore Coat Protein U domain; Region: SCPU; pfam05229
399742008204	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
399742008205	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
399742008206	PapC C-terminal domain; Region: PapC_C; pfam13953
399742008207	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
399742008208	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
399742008209	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
399742008210	Spore Coat Protein U domain; Region: SCPU; pfam05229
399742008211	Spore Coat Protein U domain; Region: SCPU; cl02253
399742008212	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
399742008213	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
399742008214	Helix-turn-helix domain; Region: HTH_28; pfam13518
399742008215	putative transposase OrfB; Reviewed; Region: PHA02517
399742008216	Homeodomain-like domain; Region: HTH_32; pfam13565
399742008217	Integrase core domain; Region: rve; pfam00665
399742008218	Integrase core domain; Region: rve_3; pfam13683
399742008219	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
399742008220	putative CheA interaction surface; other site
399742008221	chemotaxis protein CheA; Provisional; Region: PRK10547
399742008222	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
399742008223	putative binding surface; other site
399742008224	active site
399742008225	CheY binding; Region: CheY-binding; pfam09078
399742008226	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
399742008227	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742008228	ATP binding site [chemical binding]; other site
399742008229	Mg2+ binding site [ion binding]; other site
399742008230	G-X-G motif; other site
399742008231	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
399742008232	flagellar motor protein MotB; Validated; Region: motB; PRK09041
399742008233	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
399742008234	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
399742008235	ligand binding site [chemical binding]; other site
399742008236	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
399742008237	flagellar motor protein MotA; Validated; Region: PRK09110
399742008238	transcriptional activator FlhC; Provisional; Region: PRK12722
399742008239	transcriptional activator FlhD; Provisional; Region: PRK02909
399742008240	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742008241	Ligand Binding Site [chemical binding]; other site
399742008242	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
399742008243	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
399742008244	active site
399742008245	homotetramer interface [polypeptide binding]; other site
399742008246	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
399742008247	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742008248	active site
399742008249	motif I; other site
399742008250	motif II; other site
399742008251	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742008252	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742008253	TM-ABC transporter signature motif; other site
399742008254	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
399742008255	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742008256	Walker A/P-loop; other site
399742008257	ATP binding site [chemical binding]; other site
399742008258	Q-loop/lid; other site
399742008259	ABC transporter signature motif; other site
399742008260	Walker B; other site
399742008261	D-loop; other site
399742008262	H-loop/switch region; other site
399742008263	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742008264	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
399742008265	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
399742008266	ligand binding site [chemical binding]; other site
399742008267	DJ-1 family protein; Region: not_thiJ; TIGR01383
399742008268	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
399742008269	conserved cys residue [active]
399742008270	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
399742008271	Ferritin-like domain; Region: Ferritin; pfam00210
399742008272	ferroxidase diiron center [ion binding]; other site
399742008273	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
399742008274	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
399742008275	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
399742008276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008277	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742008278	putative substrate translocation pore; other site
399742008279	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008280	hypothetical protein; Provisional; Region: PRK09273
399742008281	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
399742008282	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
399742008283	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
399742008284	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742008285	substrate binding pocket [chemical binding]; other site
399742008286	membrane-bound complex binding site; other site
399742008287	hinge residues; other site
399742008288	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
399742008289	substrate binding pocket [chemical binding]; other site
399742008290	membrane-bound complex binding site; other site
399742008291	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742008292	Zn2+ binding site [ion binding]; other site
399742008293	Mg2+ binding site [ion binding]; other site
399742008294	YecR-like lipoprotein; Region: YecR; pfam13992
399742008295	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
399742008296	Ferritin-like domain; Region: Ferritin; pfam00210
399742008297	ferroxidase diiron center [ion binding]; other site
399742008298	probable metal-binding protein; Region: matur_matur; TIGR03853
399742008299	tyrosine transporter TyrP; Provisional; Region: PRK15132
399742008300	aromatic amino acid transport protein; Region: araaP; TIGR00837
399742008301	hypothetical protein; Provisional; Region: PRK10396
399742008302	Uncharacterized protein family (UPF0149); Region: UPF0149; pfam03695
399742008303	SEC-C motif; Region: SEC-C; pfam02810
399742008304	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
399742008305	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
399742008306	dimerization interface [polypeptide binding]; other site
399742008307	ligand binding site [chemical binding]; other site
399742008308	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742008309	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
399742008310	TM-ABC transporter signature motif; other site
399742008311	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
399742008312	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
399742008313	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
399742008314	TM-ABC transporter signature motif; other site
399742008315	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
399742008316	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
399742008317	Walker A/P-loop; other site
399742008318	ATP binding site [chemical binding]; other site
399742008319	Q-loop/lid; other site
399742008320	ABC transporter signature motif; other site
399742008321	Walker B; other site
399742008322	D-loop; other site
399742008323	H-loop/switch region; other site
399742008324	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
399742008325	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
399742008326	Walker A/P-loop; other site
399742008327	ATP binding site [chemical binding]; other site
399742008328	Q-loop/lid; other site
399742008329	ABC transporter signature motif; other site
399742008330	Walker B; other site
399742008331	D-loop; other site
399742008332	H-loop/switch region; other site
399742008333	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742008334	DNA-binding site [nucleotide binding]; DNA binding site
399742008335	RNA-binding motif; other site
399742008336	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
399742008337	DNA-binding site [nucleotide binding]; DNA binding site
399742008338	RNA-binding motif; other site
399742008339	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
399742008340	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
399742008341	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
399742008342	GIY-YIG motif/motif A; other site
399742008343	active site
399742008344	catalytic site [active]
399742008345	putative DNA binding site [nucleotide binding]; other site
399742008346	metal binding site [ion binding]; metal-binding site
399742008347	UvrB/uvrC motif; Region: UVR; pfam02151
399742008348	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
399742008349	Helix-hairpin-helix motif; Region: HHH; pfam00633
399742008350	response regulator; Provisional; Region: PRK09483
399742008351	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742008352	active site
399742008353	phosphorylation site [posttranslational modification]
399742008354	intermolecular recognition site; other site
399742008355	dimerization interface [polypeptide binding]; other site
399742008356	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742008357	DNA binding residues [nucleotide binding]
399742008358	dimerization interface [polypeptide binding]; other site
399742008359	hypothetical protein; Provisional; Region: PRK10613
399742008360	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
399742008361	Autoinducer binding domain; Region: Autoind_bind; pfam03472
399742008362	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742008363	DNA binding residues [nucleotide binding]
399742008364	dimerization interface [polypeptide binding]; other site
399742008365	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
399742008366	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
399742008367	Walker A/P-loop; other site
399742008368	ATP binding site [chemical binding]; other site
399742008369	Q-loop/lid; other site
399742008370	ABC transporter signature motif; other site
399742008371	Walker B; other site
399742008372	D-loop; other site
399742008373	H-loop/switch region; other site
399742008374	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
399742008375	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742008376	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742008377	dimer interface [polypeptide binding]; other site
399742008378	conserved gate region; other site
399742008379	putative PBP binding loops; other site
399742008380	ABC-ATPase subunit interface; other site
399742008381	D-cysteine desulfhydrase; Validated; Region: PRK03910
399742008382	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
399742008383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742008384	catalytic residue [active]
399742008385	cystine transporter subunit; Provisional; Region: PRK11260
399742008386	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742008387	substrate binding pocket [chemical binding]; other site
399742008388	membrane-bound complex binding site; other site
399742008389	hinge residues; other site
399742008390	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
399742008391	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
399742008392	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742008393	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
399742008394	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742008395	DNA binding residues [nucleotide binding]
399742008396	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
399742008397	Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893
399742008398	NAD(P) binding site [chemical binding]; other site
399742008399	catalytic residues [active]
399742008400	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
399742008401	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
399742008402	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
399742008403	acyl-activating enzyme (AAE) consensus motif; other site
399742008404	AMP binding site [chemical binding]; other site
399742008405	active site
399742008406	CoA binding site [chemical binding]; other site
399742008407	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
399742008408	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
399742008409	PYR/PP interface [polypeptide binding]; other site
399742008410	dimer interface [polypeptide binding]; other site
399742008411	TPP binding site [chemical binding]; other site
399742008412	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
399742008413	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
399742008414	TPP-binding site [chemical binding]; other site
399742008415	dimer interface [polypeptide binding]; other site
399742008416	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
399742008417	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742008418	NAD(P) binding site [chemical binding]; other site
399742008419	active site
399742008420	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
399742008421	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742008422	NAD(P) binding site [chemical binding]; other site
399742008423	active site
399742008424	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
399742008425	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
399742008426	putative trimer interface [polypeptide binding]; other site
399742008427	putative CoA binding site [chemical binding]; other site
399742008428	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
399742008429	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
399742008430	inhibitor-cofactor binding pocket; inhibition site
399742008431	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742008432	catalytic residue [active]
399742008433	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742008434	S-adenosylmethionine binding site [chemical binding]; other site
399742008435	Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119
399742008436	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742008437	binding surface
399742008438	TPR motif; other site
399742008439	Tetratricopeptide repeat; Region: TPR_12; pfam13424
399742008440	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
399742008441	flagellin; Provisional; Region: PRK12802
399742008442	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
399742008443	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
399742008444	flagellar capping protein; Reviewed; Region: fliD; PRK08032
399742008445	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
399742008446	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
399742008447	flagellar protein FliS; Validated; Region: fliS; PRK05685
399742008448	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
399742008449	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
399742008450	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
399742008451	active site
399742008452	Na/Ca binding site [ion binding]; other site
399742008453	catalytic site [active]
399742008454	lipoprotein; Provisional; Region: PRK10397
399742008455	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
399742008456	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
399742008457	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
399742008458	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
399742008459	flagellar motor switch protein FliG; Region: fliG; TIGR00207
399742008460	FliG C-terminal domain; Region: FliG_C; pfam01706
399742008461	flagellar assembly protein H; Validated; Region: fliH; PRK05687
399742008462	Flagellar assembly protein FliH; Region: FliH; pfam02108
399742008463	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
399742008464	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
399742008465	Walker A motif/ATP binding site; other site
399742008466	Walker B motif; other site
399742008467	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
399742008468	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
399742008469	flagellar hook-length control protein; Provisional; Region: PRK10118
399742008470	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
399742008471	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
399742008472	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
399742008473	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
399742008474	flagellar motor switch protein; Validated; Region: fliN; PRK05698
399742008475	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
399742008476	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
399742008477	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
399742008478	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
399742008479	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
399742008480	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742008481	DNA binding residues [nucleotide binding]
399742008482	dimerization interface [polypeptide binding]; other site
399742008483	hypothetical protein; Provisional; Region: PRK10708
399742008484	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
399742008485	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
399742008486	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742008487	active site
399742008488	motif I; other site
399742008489	motif II; other site
399742008490	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
399742008491	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742008492	metal binding site [ion binding]; metal-binding site
399742008493	active site
399742008494	I-site; other site
399742008495	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
399742008496	hypothetical protein; Provisional; Region: PRK10062
399742008497	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
399742008498	EamA-like transporter family; Region: EamA; pfam00892
399742008499	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
399742008500	additional DNA contacts [nucleotide binding]; other site
399742008501	mismatch recognition site; other site
399742008502	active site
399742008503	zinc binding site [ion binding]; other site
399742008504	DNA intercalation site [nucleotide binding]; other site
399742008505	DNA cytosine methylase; Provisional; Region: PRK10458
399742008506	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
399742008507	cofactor binding site; other site
399742008508	DNA binding site [nucleotide binding]
399742008509	substrate interaction site [chemical binding]; other site
399742008510	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
399742008511	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742008512	Zn2+ binding site [ion binding]; other site
399742008513	Mg2+ binding site [ion binding]; other site
399742008514	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742008515	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
399742008516	trimer interface [polypeptide binding]; other site
399742008517	eyelet of channel; other site
399742008518	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
399742008519	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
399742008520	putative active site [active]
399742008521	sensory histidine kinase DcuS; Provisional; Region: PRK11086
399742008522	PAS domain; Region: PAS; smart00091
399742008523	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742008524	ATP binding site [chemical binding]; other site
399742008525	Mg2+ binding site [ion binding]; other site
399742008526	G-X-G motif; other site
399742008527	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
399742008528	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742008529	active site
399742008530	phosphorylation site [posttranslational modification]
399742008531	intermolecular recognition site; other site
399742008532	dimerization interface [polypeptide binding]; other site
399742008533	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
399742008534	ApbE family; Region: ApbE; pfam02424
399742008535	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
399742008536	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
399742008537	putative active site [active]
399742008538	putative FMN binding site [chemical binding]; other site
399742008539	putative substrate binding site [chemical binding]; other site
399742008540	putative catalytic residue [active]
399742008541	FMN-binding domain; Region: FMN_bind; cl01081
399742008542	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
399742008543	L-aspartate oxidase; Provisional; Region: PRK06175
399742008544	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
399742008545	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
399742008546	transmembrane helices; other site
399742008547	fumarate hydratase; Provisional; Region: PRK15389
399742008548	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
399742008549	Fumarase C-terminus; Region: Fumerase_C; pfam05683
399742008550	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
399742008551	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
399742008552	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
399742008553	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742008554	dimerization interface [polypeptide binding]; other site
399742008555	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
399742008556	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742008557	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
399742008558	putative dimerization interface [polypeptide binding]; other site
399742008559	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
399742008560	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
399742008561	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
399742008562	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
399742008563	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742008564	motif II; other site
399742008565	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
399742008566	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742008567	Ligand Binding Site [chemical binding]; other site
399742008568	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
399742008569	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742008570	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
399742008571	Protein export membrane protein; Region: SecD_SecF; cl14618
399742008572	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
399742008573	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
399742008574	shikimate transporter; Provisional; Region: PRK09952
399742008575	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008576	putative substrate translocation pore; other site
399742008577	AMP nucleosidase; Provisional; Region: PRK08292
399742008578	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
399742008579	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
399742008580	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
399742008581	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
399742008582	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
399742008583	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
399742008584	active site
399742008585	MATE family multidrug exporter; Provisional; Region: PRK10189
399742008586	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
399742008587	hypothetical protein; Provisional; Region: PRK05423
399742008588	Predicted membrane protein [Function unknown]; Region: COG1289
399742008589	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
399742008590	DNA gyrase inhibitor; Provisional; Region: PRK10016
399742008591	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
399742008592	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
399742008593	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
399742008594	Colicin pore forming domain; Region: Colicin; pfam01024
399742008595	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
399742008596	Acyltransferase family; Region: Acyl_transf_3; pfam01757
399742008597	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3778
399742008598	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
399742008599	Phage protein GP46; Region: GP46; pfam07409
399742008600	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
399742008601	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
399742008602	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
399742008603	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
399742008604	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
399742008605	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
399742008606	Phage tail tube protein; Region: Tail_tube; pfam10618
399742008607	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
399742008608	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
399742008609	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
399742008610	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
399742008611	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
399742008612	oligomerization interface [polypeptide binding]; other site
399742008613	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
399742008614	Phage capsid family; Region: Phage_capsid; pfam05065
399742008615	Phage head maturation protease [General function prediction only]; Region: COG3740
399742008616	Phage-related protein [Function unknown]; Region: COG4695
399742008617	Phage portal protein; Region: Phage_portal; pfam04860
399742008618	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
399742008619	Phage terminase, small subunit; Region: Terminase_4; pfam05119
399742008620	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
399742008621	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
399742008622	active site
399742008623	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
399742008624	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
399742008625	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
399742008626	catalytic residues [active]
399742008627	Lysis protein S; Region: Lysis_S; pfam04971
399742008628	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
399742008629	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
399742008630	Protein of unknown function (DUF968); Region: DUF968; pfam06147
399742008631	MT-A70; Region: MT-A70; cl01947
399742008632	Conserved phage C-terminus (Phg_2220_C); Region: Phg_2220_C; pfam09524
399742008633	Predicted transcriptional regulator [Transcription]; Region: COG2932
399742008634	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
399742008635	Catalytic site [active]
399742008636	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
399742008637	integrase; Provisional; Region: PRK09692
399742008638	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
399742008639	active site
399742008640	Int/Topo IB signature motif; other site
399742008641	exonuclease I; Provisional; Region: sbcB; PRK11779
399742008642	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
399742008643	active site
399742008644	catalytic site [active]
399742008645	substrate binding site [chemical binding]; other site
399742008646	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
399742008647	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
399742008648	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742008649	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
399742008650	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742008651	dimerization interface [polypeptide binding]; other site
399742008652	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
399742008653	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
399742008654	putative NAD(P) binding site [chemical binding]; other site
399742008655	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
399742008656	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
399742008657	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
399742008658	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
399742008659	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
399742008660	NAD binding site [chemical binding]; other site
399742008661	dimerization interface [polypeptide binding]; other site
399742008662	product binding site; other site
399742008663	substrate binding site [chemical binding]; other site
399742008664	zinc binding site [ion binding]; other site
399742008665	catalytic residues [active]
399742008666	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
399742008667	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742008668	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742008669	homodimer interface [polypeptide binding]; other site
399742008670	catalytic residue [active]
399742008671	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
399742008672	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742008673	active site
399742008674	motif I; other site
399742008675	motif II; other site
399742008676	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
399742008677	putative active site pocket [active]
399742008678	4-fold oligomerization interface [polypeptide binding]; other site
399742008679	metal binding residues [ion binding]; metal-binding site
399742008680	3-fold/trimer interface [polypeptide binding]; other site
399742008681	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
399742008682	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
399742008683	putative active site [active]
399742008684	oxyanion strand; other site
399742008685	catalytic triad [active]
399742008686	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
399742008687	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
399742008688	catalytic residues [active]
399742008689	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
399742008690	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
399742008691	substrate binding site [chemical binding]; other site
399742008692	glutamase interaction surface [polypeptide binding]; other site
399742008693	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
399742008694	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
399742008695	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
399742008696	metal binding site [ion binding]; metal-binding site
399742008697	chain length determinant protein WzzB; Provisional; Region: PRK15471
399742008698	Chain length determinant protein; Region: Wzz; pfam02706
399742008699	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
399742008700	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
399742008701	putative NAD(P) binding site [chemical binding]; other site
399742008702	active site
399742008703	putative substrate binding site [chemical binding]; other site
399742008704	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
399742008705	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
399742008706	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
399742008707	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
399742008708	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
399742008709	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
399742008710	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
399742008711	phosphomannomutase CpsG; Provisional; Region: PRK15414
399742008712	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
399742008713	active site
399742008714	substrate binding site [chemical binding]; other site
399742008715	metal binding site [ion binding]; metal-binding site
399742008716	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
399742008717	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
399742008718	Substrate binding site; other site
399742008719	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
399742008720	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
399742008721	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
399742008722	putative ADP-binding pocket [chemical binding]; other site
399742008723	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
399742008724	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
399742008725	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
399742008726	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
399742008727	Probable Catalytic site; other site
399742008728	metal-binding site
399742008729	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
399742008730	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
399742008731	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
399742008732	extended (e) SDRs; Region: SDR_e; cd08946
399742008733	NAD(P) binding site [chemical binding]; other site
399742008734	active site
399742008735	substrate binding site [chemical binding]; other site
399742008736	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
399742008737	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
399742008738	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
399742008739	substrate binding site; other site
399742008740	tetramer interface; other site
399742008741	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
399742008742	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
399742008743	NAD binding site [chemical binding]; other site
399742008744	substrate binding site [chemical binding]; other site
399742008745	homodimer interface [polypeptide binding]; other site
399742008746	active site
399742008747	putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ; Provisional; Region: PRK09677
399742008748	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
399742008749	trimer interface [polypeptide binding]; other site
399742008750	active site
399742008751	substrate binding site [chemical binding]; other site
399742008752	CoA binding site [chemical binding]; other site
399742008753	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
399742008754	active site
399742008755	tetramer interface; other site
399742008756	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
399742008757	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
399742008758	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
399742008759	putative ADP-binding pocket [chemical binding]; other site
399742008760	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
399742008761	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
399742008762	colanic acid exporter; Provisional; Region: PRK10459
399742008763	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
399742008764	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
399742008765	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
399742008766	phosphomannomutase CpsG; Provisional; Region: PRK15414
399742008767	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
399742008768	active site
399742008769	substrate binding site [chemical binding]; other site
399742008770	metal binding site [ion binding]; metal-binding site
399742008771	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
399742008772	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
399742008773	Substrate binding site; other site
399742008774	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
399742008775	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
399742008776	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
399742008777	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
399742008778	active site
399742008779	GDP-Mannose binding site [chemical binding]; other site
399742008780	dimer interface [polypeptide binding]; other site
399742008781	modified nudix motif
399742008782	metal binding site [ion binding]; metal-binding site
399742008783	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
399742008784	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
399742008785	NADP binding site [chemical binding]; other site
399742008786	active site
399742008787	putative substrate binding site [chemical binding]; other site
399742008788	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
399742008789	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
399742008790	NADP-binding site; other site
399742008791	homotetramer interface [polypeptide binding]; other site
399742008792	substrate binding site [chemical binding]; other site
399742008793	homodimer interface [polypeptide binding]; other site
399742008794	active site
399742008795	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
399742008796	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
399742008797	putative trimer interface [polypeptide binding]; other site
399742008798	putative active site [active]
399742008799	putative substrate binding site [chemical binding]; other site
399742008800	putative CoA binding site [chemical binding]; other site
399742008801	putative glycosyl transferase; Provisional; Region: PRK10063
399742008802	colanic acid biosynthesis glycosyl transferase WcaE; Region: wcaE; TIGR04009
399742008803	active site
399742008804	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
399742008805	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
399742008806	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
399742008807	putative acyl transferase; Provisional; Region: PRK10191
399742008808	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
399742008809	trimer interface [polypeptide binding]; other site
399742008810	active site
399742008811	substrate binding site [chemical binding]; other site
399742008812	CoA binding site [chemical binding]; other site
399742008813	putative glycosyl transferase; Provisional; Region: PRK10018
399742008814	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
399742008815	active site
399742008816	tyrosine kinase; Provisional; Region: PRK11519
399742008817	Chain length determinant protein; Region: Wzz; pfam02706
399742008818	Chain length determinant protein; Region: Wzz; cl15801
399742008819	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
399742008820	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
399742008821	Low molecular weight phosphatase family; Region: LMWPc; cd00115
399742008822	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
399742008823	active site
399742008824	polysaccharide export protein Wza; Provisional; Region: PRK15078
399742008825	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
399742008826	SLBB domain; Region: SLBB; pfam10531
399742008827	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
399742008828	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
399742008829	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
399742008830	Transporter associated domain; Region: CorC_HlyC; smart01091
399742008831	putative assembly protein; Provisional; Region: PRK10833
399742008832	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
399742008833	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
399742008834	trimer interface [polypeptide binding]; other site
399742008835	active site
399742008836	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
399742008837	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
399742008838	ATP-binding site [chemical binding]; other site
399742008839	Sugar specificity; other site
399742008840	Pyrimidine base specificity; other site
399742008841	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
399742008842	putative diguanylate cyclase; Provisional; Region: PRK09776
399742008843	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742008844	putative active site [active]
399742008845	heme pocket [chemical binding]; other site
399742008846	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742008847	putative active site [active]
399742008848	heme pocket [chemical binding]; other site
399742008849	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742008850	putative active site [active]
399742008851	heme pocket [chemical binding]; other site
399742008852	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742008853	metal binding site [ion binding]; metal-binding site
399742008854	active site
399742008855	I-site; other site
399742008856	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742008857	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
399742008858	AlkA N-terminal domain; Region: AlkA_N; smart01009
399742008859	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
399742008860	minor groove reading motif; other site
399742008861	helix-hairpin-helix signature motif; other site
399742008862	substrate binding pocket [chemical binding]; other site
399742008863	active site
399742008864	putative chaperone; Provisional; Region: PRK11678
399742008865	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
399742008866	nucleotide binding site [chemical binding]; other site
399742008867	putative NEF/HSP70 interaction site [polypeptide binding]; other site
399742008868	SBD interface [polypeptide binding]; other site
399742008869	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
399742008870	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742008871	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742008872	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
399742008873	Protein export membrane protein; Region: SecD_SecF; cl14618
399742008874	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
399742008875	putative transporter; Provisional; Region: PRK10504
399742008876	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008877	putative substrate translocation pore; other site
399742008878	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008879	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
399742008880	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742008881	dimerization interface [polypeptide binding]; other site
399742008882	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742008883	dimer interface [polypeptide binding]; other site
399742008884	phosphorylation site [posttranslational modification]
399742008885	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742008886	ATP binding site [chemical binding]; other site
399742008887	Mg2+ binding site [ion binding]; other site
399742008888	G-X-G motif; other site
399742008889	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
399742008890	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742008891	active site
399742008892	phosphorylation site [posttranslational modification]
399742008893	intermolecular recognition site; other site
399742008894	dimerization interface [polypeptide binding]; other site
399742008895	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742008896	DNA binding site [nucleotide binding]
399742008897	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
399742008898	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742008899	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
399742008900	homotrimer interaction site [polypeptide binding]; other site
399742008901	putative active site [active]
399742008902	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742008903	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742008904	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742008905	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742008906	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742008907	putative substrate translocation pore; other site
399742008908	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
399742008909	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
399742008910	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
399742008911	active site
399742008912	metal binding site [ion binding]; metal-binding site
399742008913	putative protease; Provisional; Region: PRK15452
399742008914	Peptidase family U32; Region: Peptidase_U32; pfam01136
399742008915	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
399742008916	catalytic residues [active]
399742008917	dimer interface [polypeptide binding]; other site
399742008918	Domain of unknown function (DUF4263); Region: DUF4263; pfam14082
399742008919	lipid kinase; Reviewed; Region: PRK13054
399742008920	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
399742008921	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
399742008922	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742008923	Walker A/P-loop; other site
399742008924	ATP binding site [chemical binding]; other site
399742008925	Q-loop/lid; other site
399742008926	ABC transporter signature motif; other site
399742008927	Walker B; other site
399742008928	D-loop; other site
399742008929	H-loop/switch region; other site
399742008930	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
399742008931	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742008932	Walker A/P-loop; other site
399742008933	ATP binding site [chemical binding]; other site
399742008934	Q-loop/lid; other site
399742008935	ABC transporter signature motif; other site
399742008936	Walker B; other site
399742008937	D-loop; other site
399742008938	H-loop/switch region; other site
399742008939	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
399742008940	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
399742008941	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
399742008942	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
399742008943	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742008944	dimer interface [polypeptide binding]; other site
399742008945	conserved gate region; other site
399742008946	putative PBP binding loops; other site
399742008947	ABC-ATPase subunit interface; other site
399742008948	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
399742008949	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
399742008950	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
399742008951	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 4. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_4; cd03329
399742008952	putative active site pocket [active]
399742008953	metal binding site [ion binding]; metal-binding site
399742008954	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
399742008955	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
399742008956	putative active site; other site
399742008957	catalytic residue [active]
399742008958	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
399742008959	dimer interface [polypeptide binding]; other site
399742008960	substrate binding site [chemical binding]; other site
399742008961	ATP binding site [chemical binding]; other site
399742008962	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
399742008963	substrate binding site [chemical binding]; other site
399742008964	multimerization interface [polypeptide binding]; other site
399742008965	ATP binding site [chemical binding]; other site
399742008966	type IV conjugative transfer system lipoprotein TraV; Region: TraV; TIGR02747
399742008967	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
399742008968	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742008969	inhibitor-cofactor binding pocket; inhibition site
399742008970	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742008971	catalytic residue [active]
399742008972	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
399742008973	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742008974	catalytic residue [active]
399742008975	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
399742008976	Chain length determinant protein; Region: Wzz; pfam02706
399742008977	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
399742008978	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
399742008979	Low molecular weight phosphatase family; Region: LMWPc; cd00115
399742008980	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
399742008981	active site
399742008982	polysaccharide export protein Wza; Provisional; Region: PRK15078
399742008983	C2 domain; Region: C2; cl14603
399742008984	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
399742008985	SLBB domain; Region: SLBB; pfam10531
399742008986	SLBB domain; Region: SLBB; pfam10531
399742008987	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
399742008988	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
399742008989	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742008990	Coenzyme A binding pocket [chemical binding]; other site
399742008991	antiporter inner membrane protein; Provisional; Region: PRK11670
399742008992	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
399742008993	Walker A motif; other site
399742008994	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
399742008995	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
399742008996	active site
399742008997	HIGH motif; other site
399742008998	KMSKS motif; other site
399742008999	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
399742009000	tRNA binding surface [nucleotide binding]; other site
399742009001	anticodon binding site; other site
399742009002	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
399742009003	dimer interface [polypeptide binding]; other site
399742009004	putative tRNA-binding site [nucleotide binding]; other site
399742009005	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
399742009006	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
399742009007	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
399742009008	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
399742009009	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742009010	active site
399742009011	phosphorylation site [posttranslational modification]
399742009012	intermolecular recognition site; other site
399742009013	dimerization interface [polypeptide binding]; other site
399742009014	LytTr DNA-binding domain; Region: LytTR; pfam04397
399742009015	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
399742009016	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
399742009017	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
399742009018	Histidine kinase; Region: His_kinase; pfam06580
399742009019	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742009020	ATP binding site [chemical binding]; other site
399742009021	Mg2+ binding site [ion binding]; other site
399742009022	G-X-G motif; other site
399742009023	transcriptional regulator MirA; Provisional; Region: PRK15043
399742009024	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
399742009025	DNA binding residues [nucleotide binding]
399742009026	hypothetical protein; Provisional; Region: PRK13681
399742009027	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009028	dimer interface [polypeptide binding]; other site
399742009029	conserved gate region; other site
399742009030	putative PBP binding loops; other site
399742009031	ABC-ATPase subunit interface; other site
399742009032	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
399742009033	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
399742009034	Walker A/P-loop; other site
399742009035	ATP binding site [chemical binding]; other site
399742009036	Q-loop/lid; other site
399742009037	ABC transporter signature motif; other site
399742009038	Walker B; other site
399742009039	D-loop; other site
399742009040	H-loop/switch region; other site
399742009041	CBS domain; Region: CBS; pfam00571
399742009042	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
399742009043	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
399742009044	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
399742009045	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
399742009046	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
399742009047	D-lactate dehydrogenase; Provisional; Region: PRK11183
399742009048	FAD binding domain; Region: FAD_binding_4; pfam01565
399742009049	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
399742009050	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
399742009051	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742009052	Coenzyme A binding pocket [chemical binding]; other site
399742009053	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
399742009054	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
399742009055	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
399742009056	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
399742009057	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
399742009058	oxidoreductase; Provisional; Region: PRK12743
399742009059	classical (c) SDRs; Region: SDR_c; cd05233
399742009060	NAD(P) binding site [chemical binding]; other site
399742009061	active site
399742009062	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
399742009063	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
399742009064	beta-galactosidase; Region: BGL; TIGR03356
399742009065	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
399742009066	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742009067	active site turn [active]
399742009068	phosphorylation site [posttranslational modification]
399742009069	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742009070	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
399742009071	HPr interaction site; other site
399742009072	glycerol kinase (GK) interaction site [polypeptide binding]; other site
399742009073	active site
399742009074	phosphorylation site [posttranslational modification]
399742009075	transcriptional antiterminator BglG; Provisional; Region: PRK09772
399742009076	CAT RNA binding domain; Region: CAT_RBD; smart01061
399742009077	PRD domain; Region: PRD; pfam00874
399742009078	PRD domain; Region: PRD; pfam00874
399742009079	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
399742009080	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
399742009081	FMN binding site [chemical binding]; other site
399742009082	active site
399742009083	catalytic residues [active]
399742009084	substrate binding site [chemical binding]; other site
399742009085	hypothetical protein; Provisional; Region: PRK01821
399742009086	hypothetical protein; Provisional; Region: PRK10711
399742009087	cytidine deaminase; Provisional; Region: PRK09027
399742009088	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
399742009089	active site
399742009090	catalytic motif [active]
399742009091	Zn binding site [ion binding]; other site
399742009092	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
399742009093	active site
399742009094	catalytic motif [active]
399742009095	Zn binding site [ion binding]; other site
399742009096	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
399742009097	putative active site [active]
399742009098	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742009099	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742009100	TM-ABC transporter signature motif; other site
399742009101	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742009102	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
399742009103	Walker A/P-loop; other site
399742009104	ATP binding site [chemical binding]; other site
399742009105	Q-loop/lid; other site
399742009106	ABC transporter signature motif; other site
399742009107	Walker B; other site
399742009108	D-loop; other site
399742009109	H-loop/switch region; other site
399742009110	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742009111	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
399742009112	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
399742009113	ligand binding site [chemical binding]; other site
399742009114	calcium binding site [ion binding]; other site
399742009115	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
399742009116	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742009117	DNA binding site [nucleotide binding]
399742009118	domain linker motif; other site
399742009119	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
399742009120	dimerization interface (closed form) [polypeptide binding]; other site
399742009121	ligand binding site [chemical binding]; other site
399742009122	Predicted membrane protein [Function unknown]; Region: COG2311
399742009123	hypothetical protein; Provisional; Region: PRK10835
399742009124	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
399742009125	GTP cyclohydrolase I; Provisional; Region: PLN03044
399742009126	active site
399742009127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742009128	putative substrate translocation pore; other site
399742009129	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
399742009130	S-formylglutathione hydrolase; Region: PLN02442
399742009131	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
399742009132	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742009133	N-terminal plug; other site
399742009134	ligand-binding site [chemical binding]; other site
399742009135	lysine transporter; Provisional; Region: PRK10836
399742009136	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
399742009137	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742009138	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
399742009139	putative dimerization interface [polypeptide binding]; other site
399742009140	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
399742009141	endonuclease IV; Provisional; Region: PRK01060
399742009142	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
399742009143	DNA interaction; other site
399742009144	Metal-binding active site; metal-binding site
399742009145	AP (apurinic/apyrimidinic) site pocket; other site
399742009146	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
399742009147	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
399742009148	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
399742009149	active site
399742009150	P-loop; other site
399742009151	phosphorylation site [posttranslational modification]
399742009152	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
399742009153	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
399742009154	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
399742009155	putative substrate binding site [chemical binding]; other site
399742009156	putative ATP binding site [chemical binding]; other site
399742009157	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
399742009158	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
399742009159	active site
399742009160	phosphorylation site [posttranslational modification]
399742009161	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
399742009162	dimerization domain swap beta strand [polypeptide binding]; other site
399742009163	regulatory protein interface [polypeptide binding]; other site
399742009164	active site
399742009165	regulatory phosphorylation site [posttranslational modification]; other site
399742009166	sugar efflux transporter B; Provisional; Region: PRK15011
399742009167	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742009168	putative substrate translocation pore; other site
399742009169	Flagellin N-methylase; Region: FliB; pfam03692
399742009170	elongation factor P; Provisional; Region: PRK04542
399742009171	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
399742009172	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
399742009173	RNA binding site [nucleotide binding]; other site
399742009174	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
399742009175	RNA binding site [nucleotide binding]; other site
399742009176	mannonate dehydratase; Provisional; Region: PRK03906
399742009177	mannonate dehydratase; Region: uxuA; TIGR00695
399742009178	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
399742009179	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
399742009180	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
399742009181	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
399742009182	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
399742009183	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; cl08458
399742009184	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
399742009185	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
399742009186	active site
399742009187	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
399742009188	NlpC/P60 family; Region: NLPC_P60; pfam00877
399742009189	phage resistance protein; Provisional; Region: PRK10551
399742009190	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
399742009191	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742009192	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
399742009193	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
399742009194	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
399742009195	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009196	dimer interface [polypeptide binding]; other site
399742009197	conserved gate region; other site
399742009198	putative PBP binding loops; other site
399742009199	ABC-ATPase subunit interface; other site
399742009200	microcin C ABC transporter permease; Provisional; Region: PRK15021
399742009201	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009202	dimer interface [polypeptide binding]; other site
399742009203	conserved gate region; other site
399742009204	ABC-ATPase subunit interface; other site
399742009205	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
399742009206	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742009207	Walker A/P-loop; other site
399742009208	ATP binding site [chemical binding]; other site
399742009209	Q-loop/lid; other site
399742009210	ABC transporter signature motif; other site
399742009211	Walker B; other site
399742009212	D-loop; other site
399742009213	H-loop/switch region; other site
399742009214	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
399742009215	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
399742009216	Walker A/P-loop; other site
399742009217	ATP binding site [chemical binding]; other site
399742009218	Q-loop/lid; other site
399742009219	ABC transporter signature motif; other site
399742009220	Walker B; other site
399742009221	D-loop; other site
399742009222	H-loop/switch region; other site
399742009223	hypothetical protein; Provisional; Region: PRK11835
399742009224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742009225	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
399742009226	putative substrate translocation pore; other site
399742009227	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
399742009228	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742009229	RNA binding surface [nucleotide binding]; other site
399742009230	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
399742009231	active site
399742009232	uracil binding [chemical binding]; other site
399742009233	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
399742009234	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742009235	ATP binding site [chemical binding]; other site
399742009236	putative Mg++ binding site [ion binding]; other site
399742009237	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742009238	nucleotide binding region [chemical binding]; other site
399742009239	ATP-binding site [chemical binding]; other site
399742009240	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
399742009241	5S rRNA interface [nucleotide binding]; other site
399742009242	CTC domain interface [polypeptide binding]; other site
399742009243	L16 interface [polypeptide binding]; other site
399742009244	Nucleoid-associated protein [General function prediction only]; Region: COG3081
399742009245	nucleoid-associated protein NdpA; Validated; Region: PRK00378
399742009246	hypothetical protein; Provisional; Region: PRK13689
399742009247	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
399742009248	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
399742009249	Sulfatase; Region: Sulfatase; pfam00884
399742009250	putative major fimbrial protein SthE; Provisional; Region: PRK15292
399742009251	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
399742009252	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
399742009253	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
399742009254	secondary substrate binding site; other site
399742009255	primary substrate binding site; other site
399742009256	inhibition loop; other site
399742009257	dimerization interface [polypeptide binding]; other site
399742009258	malate:quinone oxidoreductase; Validated; Region: PRK05257
399742009259	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
399742009260	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
399742009261	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
399742009262	Sulfate transporter family; Region: Sulfate_transp; pfam00916
399742009263	MgtE intracellular N domain; Region: MgtE_N; cl15244
399742009264	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
399742009265	MgtE intracellular N domain; Region: MgtE_N; smart00924
399742009266	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
399742009267	Divalent cation transporter; Region: MgtE; cl00786
399742009268	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
399742009269	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
399742009270	Walker A/P-loop; other site
399742009271	ATP binding site [chemical binding]; other site
399742009272	Q-loop/lid; other site
399742009273	ABC transporter signature motif; other site
399742009274	Walker B; other site
399742009275	D-loop; other site
399742009276	H-loop/switch region; other site
399742009277	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
399742009278	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
399742009279	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
399742009280	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742009281	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742009282	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
399742009283	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
399742009284	DNA binding site [nucleotide binding]
399742009285	active site
399742009286	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
399742009287	ApbE family; Region: ApbE; pfam02424
399742009288	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
399742009289	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
399742009290	trimer interface [polypeptide binding]; other site
399742009291	eyelet of channel; other site
399742009292	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
399742009293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742009294	ATP binding site [chemical binding]; other site
399742009295	Mg2+ binding site [ion binding]; other site
399742009296	G-X-G motif; other site
399742009297	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
399742009298	putative binding surface; other site
399742009299	active site
399742009300	transcriptional regulator RcsB; Provisional; Region: PRK10840
399742009301	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742009302	active site
399742009303	phosphorylation site [posttranslational modification]
399742009304	intermolecular recognition site; other site
399742009305	dimerization interface [polypeptide binding]; other site
399742009306	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742009307	DNA binding residues [nucleotide binding]
399742009308	dimerization interface [polypeptide binding]; other site
399742009309	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
399742009310	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742009311	dimer interface [polypeptide binding]; other site
399742009312	phosphorylation site [posttranslational modification]
399742009313	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742009314	ATP binding site [chemical binding]; other site
399742009315	Mg2+ binding site [ion binding]; other site
399742009316	G-X-G motif; other site
399742009317	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
399742009318	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742009319	active site
399742009320	phosphorylation site [posttranslational modification]
399742009321	intermolecular recognition site; other site
399742009322	dimerization interface [polypeptide binding]; other site
399742009323	DNA gyrase subunit A; Validated; Region: PRK05560
399742009324	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
399742009325	CAP-like domain; other site
399742009326	active site
399742009327	primary dimer interface [polypeptide binding]; other site
399742009328	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
399742009329	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
399742009330	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
399742009331	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
399742009332	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
399742009333	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
399742009334	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
399742009335	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742009336	S-adenosylmethionine binding site [chemical binding]; other site
399742009337	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
399742009338	ATP cone domain; Region: ATP-cone; pfam03477
399742009339	Class I ribonucleotide reductase; Region: RNR_I; cd01679
399742009340	active site
399742009341	dimer interface [polypeptide binding]; other site
399742009342	catalytic residues [active]
399742009343	effector binding site; other site
399742009344	R2 peptide binding site; other site
399742009345	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
399742009346	dimer interface [polypeptide binding]; other site
399742009347	putative radical transfer pathway; other site
399742009348	diiron center [ion binding]; other site
399742009349	tyrosyl radical; other site
399742009350	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
399742009351	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
399742009352	catalytic loop [active]
399742009353	iron binding site [ion binding]; other site
399742009354	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
399742009355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742009356	putative substrate translocation pore; other site
399742009357	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
399742009358	hydroxyglutarate oxidase; Provisional; Region: PRK11728
399742009359	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
399742009360	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
399742009361	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
399742009362	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
399742009363	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
399742009364	Cysteine-rich domain; Region: CCG; pfam02754
399742009365	Cysteine-rich domain; Region: CCG; pfam02754
399742009366	hypothetical protein; Provisional; Region: PRK03673
399742009367	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
399742009368	putative MPT binding site; other site
399742009369	Competence-damaged protein; Region: CinA; cl00666
399742009370	YfaZ precursor; Region: YfaZ; pfam07437
399742009371	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
399742009372	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
399742009373	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
399742009374	acyl-activating enzyme (AAE) consensus motif; other site
399742009375	putative AMP binding site [chemical binding]; other site
399742009376	putative active site [active]
399742009377	putative CoA binding site [chemical binding]; other site
399742009378	O-succinylbenzoate synthase; Provisional; Region: PRK05105
399742009379	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
399742009380	active site
399742009381	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
399742009382	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
399742009383	substrate binding site [chemical binding]; other site
399742009384	oxyanion hole (OAH) forming residues; other site
399742009385	trimer interface [polypeptide binding]; other site
399742009386	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
399742009387	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
399742009388	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
399742009389	dimer interface [polypeptide binding]; other site
399742009390	tetramer interface [polypeptide binding]; other site
399742009391	PYR/PP interface [polypeptide binding]; other site
399742009392	TPP binding site [chemical binding]; other site
399742009393	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
399742009394	TPP-binding site; other site
399742009395	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
399742009396	chorismate binding enzyme; Region: Chorismate_bind; cl10555
399742009397	hypothetical protein; Provisional; Region: PRK10404
399742009398	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742009399	Coenzyme A binding pocket [chemical binding]; other site
399742009400	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
399742009401	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
399742009402	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
399742009403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742009404	active site
399742009405	phosphorylation site [posttranslational modification]
399742009406	intermolecular recognition site; other site
399742009407	dimerization interface [polypeptide binding]; other site
399742009408	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
399742009409	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
399742009410	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
399742009411	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
399742009412	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
399742009413	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
399742009414	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
399742009415	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
399742009416	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
399742009417	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
399742009418	4Fe-4S binding domain; Region: Fer4; pfam00037
399742009419	4Fe-4S binding domain; Region: Fer4; pfam00037
399742009420	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
399742009421	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
399742009422	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
399742009423	catalytic loop [active]
399742009424	iron binding site [ion binding]; other site
399742009425	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
399742009426	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
399742009427	[4Fe-4S] binding site [ion binding]; other site
399742009428	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
399742009429	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
399742009430	SLBB domain; Region: SLBB; pfam10531
399742009431	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
399742009432	NADH dehydrogenase subunit E; Validated; Region: PRK07539
399742009433	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
399742009434	putative dimer interface [polypeptide binding]; other site
399742009435	[2Fe-2S] cluster binding site [ion binding]; other site
399742009436	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
399742009437	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
399742009438	NADH dehydrogenase subunit D; Validated; Region: PRK06075
399742009439	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
399742009440	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
399742009441	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
399742009442	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742009443	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
399742009444	putative dimerization interface [polypeptide binding]; other site
399742009445	aminotransferase AlaT; Validated; Region: PRK09265
399742009446	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742009447	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742009448	homodimer interface [polypeptide binding]; other site
399742009449	catalytic residue [active]
399742009450	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742009451	Zn2+ binding site [ion binding]; other site
399742009452	Mg2+ binding site [ion binding]; other site
399742009453	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
399742009454	transmembrane helices; other site
399742009455	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
399742009456	TrkA-C domain; Region: TrkA_C; pfam02080
399742009457	TrkA-C domain; Region: TrkA_C; pfam02080
399742009458	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
399742009459	putative phosphatase; Provisional; Region: PRK11587
399742009460	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742009461	motif II; other site
399742009462	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
399742009463	hypothetical protein; Validated; Region: PRK05445
399742009464	hypothetical protein; Provisional; Region: PRK01816
399742009465	propionate/acetate kinase; Provisional; Region: PRK12379
399742009466	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
399742009467	phosphate acetyltransferase; Reviewed; Region: PRK05632
399742009468	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
399742009469	DRTGG domain; Region: DRTGG; pfam07085
399742009470	phosphate acetyltransferase; Region: pta; TIGR00651
399742009471	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
399742009472	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
399742009473	PYR/PP interface [polypeptide binding]; other site
399742009474	dimer interface [polypeptide binding]; other site
399742009475	TPP binding site [chemical binding]; other site
399742009476	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
399742009477	transketolase; Reviewed; Region: PRK05899
399742009478	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
399742009479	TPP-binding site [chemical binding]; other site
399742009480	dimer interface [polypeptide binding]; other site
399742009481	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
399742009482	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
399742009483	active site
399742009484	P-loop; other site
399742009485	phosphorylation site [posttranslational modification]
399742009486	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
399742009487	active site
399742009488	phosphorylation site [posttranslational modification]
399742009489	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742009490	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742009491	DNA binding site [nucleotide binding]
399742009492	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
399742009493	putative dimerization interface [polypeptide binding]; other site
399742009494	putative ligand binding site [chemical binding]; other site
399742009495	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
399742009496	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
399742009497	nudix motif; other site
399742009498	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
399742009499	active site
399742009500	metal binding site [ion binding]; metal-binding site
399742009501	homotetramer interface [polypeptide binding]; other site
399742009502	glutathione S-transferase; Provisional; Region: PRK15113
399742009503	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
399742009504	C-terminal domain interface [polypeptide binding]; other site
399742009505	GSH binding site (G-site) [chemical binding]; other site
399742009506	dimer interface [polypeptide binding]; other site
399742009507	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
399742009508	N-terminal domain interface [polypeptide binding]; other site
399742009509	putative dimer interface [polypeptide binding]; other site
399742009510	putative substrate binding pocket (H-site) [chemical binding]; other site
399742009511	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
399742009512	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
399742009513	C-terminal domain interface [polypeptide binding]; other site
399742009514	GSH binding site (G-site) [chemical binding]; other site
399742009515	dimer interface [polypeptide binding]; other site
399742009516	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
399742009517	N-terminal domain interface [polypeptide binding]; other site
399742009518	putative dimer interface [polypeptide binding]; other site
399742009519	active site
399742009520	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
399742009521	homooctamer interface [polypeptide binding]; other site
399742009522	active site
399742009523	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
399742009524	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
399742009525	putative NAD(P) binding site [chemical binding]; other site
399742009526	putative active site [active]
399742009527	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
399742009528	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742009529	Coenzyme A binding pocket [chemical binding]; other site
399742009530	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
399742009531	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
399742009532	Walker A/P-loop; other site
399742009533	ATP binding site [chemical binding]; other site
399742009534	Q-loop/lid; other site
399742009535	ABC transporter signature motif; other site
399742009536	Walker B; other site
399742009537	D-loop; other site
399742009538	H-loop/switch region; other site
399742009539	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742009540	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009541	dimer interface [polypeptide binding]; other site
399742009542	conserved gate region; other site
399742009543	putative PBP binding loops; other site
399742009544	ABC-ATPase subunit interface; other site
399742009545	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
399742009546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009547	dimer interface [polypeptide binding]; other site
399742009548	conserved gate region; other site
399742009549	putative PBP binding loops; other site
399742009550	ABC-ATPase subunit interface; other site
399742009551	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
399742009552	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742009553	substrate binding pocket [chemical binding]; other site
399742009554	membrane-bound complex binding site; other site
399742009555	hinge residues; other site
399742009556	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
399742009557	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742009558	substrate binding pocket [chemical binding]; other site
399742009559	membrane-bound complex binding site; other site
399742009560	hinge residues; other site
399742009561	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
399742009562	Flavoprotein; Region: Flavoprotein; pfam02441
399742009563	amidophosphoribosyltransferase; Provisional; Region: PRK09246
399742009564	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
399742009565	active site
399742009566	tetramer interface [polypeptide binding]; other site
399742009567	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742009568	active site
399742009569	colicin V production protein; Provisional; Region: PRK10845
399742009570	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
399742009571	cell division protein DedD; Provisional; Region: PRK11633
399742009572	Sporulation related domain; Region: SPOR; pfam05036
399742009573	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
399742009574	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
399742009575	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
399742009576	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
399742009577	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
399742009578	hypothetical protein; Provisional; Region: PRK10847
399742009579	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
399742009580	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
399742009581	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
399742009582	dimerization interface 3.5A [polypeptide binding]; other site
399742009583	active site
399742009584	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
399742009585	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
399742009586	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
399742009587	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
399742009588	ligand binding site [chemical binding]; other site
399742009589	NAD binding site [chemical binding]; other site
399742009590	catalytic site [active]
399742009591	homodimer interface [polypeptide binding]; other site
399742009592	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
399742009593	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
399742009594	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
399742009595	dimer interface [polypeptide binding]; other site
399742009596	active site
399742009597	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
399742009598	Uncharacterized conserved protein [Function unknown]; Region: COG4121
399742009599	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
399742009600	YfcL protein; Region: YfcL; pfam08891
399742009601	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
399742009602	hypothetical protein; Provisional; Region: PRK10621
399742009603	Predicted permeases [General function prediction only]; Region: COG0730
399742009604	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
399742009605	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
399742009606	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
399742009607	Tetramer interface [polypeptide binding]; other site
399742009608	active site
399742009609	FMN-binding site [chemical binding]; other site
399742009610	HemK family putative methylases; Region: hemK_fam; TIGR00536
399742009611	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742009612	S-adenosylmethionine binding site [chemical binding]; other site
399742009613	hypothetical protein; Provisional; Region: PRK04946
399742009614	Uncharacterized protein family (UPF0147); Region: UPF0147; cl00739
399742009615	Smr domain; Region: Smr; pfam01713
399742009616	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
399742009617	catalytic core [active]
399742009618	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
399742009619	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
399742009620	substrate binding site [chemical binding]; other site
399742009621	oxyanion hole (OAH) forming residues; other site
399742009622	trimer interface [polypeptide binding]; other site
399742009623	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
399742009624	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
399742009625	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
399742009626	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
399742009627	dimer interface [polypeptide binding]; other site
399742009628	active site
399742009629	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
399742009630	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
399742009631	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
399742009632	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
399742009633	integrase; Provisional; Region: PRK09692
399742009634	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
399742009635	active site
399742009636	Int/Topo IB signature motif; other site
399742009637	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
399742009638	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
399742009639	catalytic residues [active]
399742009640	catalytic nucleophile [active]
399742009641	Recombinase; Region: Recombinase; pfam07508
399742009642	ParB-like nuclease domain; Region: ParB; smart00470
399742009643	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
399742009644	ParB-like nuclease domain; Region: ParB; smart00470
399742009645	RepB plasmid partitioning protein; Region: RepB; pfam07506
399742009646	sporadically distributed protein, TIGR04141 family; Region: TIGR04141
399742009647	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
399742009648	His-Xaa-Ser system radical SAM maturase HxsC; Region: rSAM_pair_HxsC; TIGR03977
399742009649	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742009650	FeS/SAM binding site; other site
399742009651	His-Xaa-Ser system radical SAM maturase HxsB; Region: rSAM_paired_1; TIGR03978
399742009652	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742009653	FeS/SAM binding site; other site
399742009654	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
399742009655	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688
399742009656	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
399742009657	active site
399742009658	catalytic residues [active]
399742009659	DNA binding site [nucleotide binding]
399742009660	Int/Topo IB signature motif; other site
399742009661	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
399742009662	active site
399742009663	Int/Topo IB signature motif; other site
399742009664	catalytic residues [active]
399742009665	DNA binding site [nucleotide binding]
399742009666	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
399742009667	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
399742009668	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
399742009669	ImpA domain protein; Region: DUF3702; pfam12486
399742009670	hypothetical protein; Provisional; Region: PRK10040
399742009671	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
399742009672	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
399742009673	Protein of unknown function (DUF1305); Region: DUF1305; cl01404
399742009674	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
399742009675	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
399742009676	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
399742009677	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
399742009678	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
399742009679	Protein of unknown function (DUF877); Region: DUF877; pfam05943
399742009680	Protein of unknown function (DUF770); Region: DUF770; pfam05591
399742009681	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
399742009682	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
399742009683	putative acyl-acceptor binding pocket; other site
399742009684	aminotransferase; Validated; Region: PRK08175
399742009685	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742009686	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742009687	homodimer interface [polypeptide binding]; other site
399742009688	catalytic residue [active]
399742009689	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
399742009690	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
399742009691	GAF domain; Region: GAF; pfam01590
399742009692	Histidine kinase; Region: His_kinase; pfam06580
399742009693	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742009694	ATP binding site [chemical binding]; other site
399742009695	Mg2+ binding site [ion binding]; other site
399742009696	G-X-G motif; other site
399742009697	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
399742009698	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742009699	active site
399742009700	phosphorylation site [posttranslational modification]
399742009701	intermolecular recognition site; other site
399742009702	dimerization interface [polypeptide binding]; other site
399742009703	LytTr DNA-binding domain; Region: LytTR; pfam04397
399742009704	glucokinase; Provisional; Region: glk; PRK00292
399742009705	glucokinase, proteobacterial type; Region: glk; TIGR00749
399742009706	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
399742009707	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
399742009708	Cl- selectivity filter; other site
399742009709	Cl- binding residues [ion binding]; other site
399742009710	pore gating glutamate residue; other site
399742009711	dimer interface [polypeptide binding]; other site
399742009712	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
399742009713	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
399742009714	dimer interface [polypeptide binding]; other site
399742009715	PYR/PP interface [polypeptide binding]; other site
399742009716	TPP binding site [chemical binding]; other site
399742009717	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
399742009718	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
399742009719	TPP-binding site [chemical binding]; other site
399742009720	dimer interface [polypeptide binding]; other site
399742009721	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742009722	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742009723	active site
399742009724	catalytic tetrad [active]
399742009725	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
399742009726	manganese transport protein MntH; Reviewed; Region: PRK00701
399742009727	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
399742009728	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
399742009729	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
399742009730	Nucleoside recognition; Region: Gate; pfam07670
399742009731	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
399742009732	MASE1; Region: MASE1; pfam05231
399742009733	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
399742009734	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742009735	diguanylate cyclase; Region: GGDEF; smart00267
399742009736	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742009737	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
399742009738	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
399742009739	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
399742009740	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
399742009741	active site
399742009742	HIGH motif; other site
399742009743	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
399742009744	active site
399742009745	KMSKS motif; other site
399742009746	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
399742009747	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742009748	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
399742009749	putative dimerization interface [polypeptide binding]; other site
399742009750	putative substrate binding pocket [chemical binding]; other site
399742009751	nucleoside transporter; Region: 2A0110; TIGR00889
399742009752	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742009753	putative substrate translocation pore; other site
399742009754	purine nucleoside phosphorylase; Provisional; Region: PRK08202
399742009755	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742009756	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742009757	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
399742009758	putative dimerization interface [polypeptide binding]; other site
399742009759	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
399742009760	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
399742009761	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
399742009762	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
399742009763	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
399742009764	nucleotide binding pocket [chemical binding]; other site
399742009765	K-X-D-G motif; other site
399742009766	catalytic site [active]
399742009767	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
399742009768	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
399742009769	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
399742009770	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
399742009771	Dimer interface [polypeptide binding]; other site
399742009772	BRCT sequence motif; other site
399742009773	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
399742009774	cell division protein ZipA; Provisional; Region: PRK03427
399742009775	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
399742009776	FtsZ protein binding site [polypeptide binding]; other site
399742009777	putative sulfate transport protein CysZ; Validated; Region: PRK04949
399742009778	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
399742009779	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
399742009780	dimer interface [polypeptide binding]; other site
399742009781	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742009782	catalytic residue [active]
399742009783	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
399742009784	dimerization domain swap beta strand [polypeptide binding]; other site
399742009785	regulatory protein interface [polypeptide binding]; other site
399742009786	active site
399742009787	regulatory phosphorylation site [posttranslational modification]; other site
399742009788	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
399742009789	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
399742009790	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
399742009791	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
399742009792	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
399742009793	HPr interaction site; other site
399742009794	glycerol kinase (GK) interaction site [polypeptide binding]; other site
399742009795	active site
399742009796	phosphorylation site [posttranslational modification]
399742009797	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
399742009798	dimer interface [polypeptide binding]; other site
399742009799	pyridoxamine kinase; Validated; Region: PRK05756
399742009800	pyridoxal binding site [chemical binding]; other site
399742009801	ATP binding site [chemical binding]; other site
399742009802	cysteine synthase B; Region: cysM; TIGR01138
399742009803	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
399742009804	dimer interface [polypeptide binding]; other site
399742009805	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742009806	catalytic residue [active]
399742009807	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
399742009808	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
399742009809	Walker A/P-loop; other site
399742009810	ATP binding site [chemical binding]; other site
399742009811	Q-loop/lid; other site
399742009812	ABC transporter signature motif; other site
399742009813	Walker B; other site
399742009814	D-loop; other site
399742009815	H-loop/switch region; other site
399742009816	TOBE-like domain; Region: TOBE_3; pfam12857
399742009817	sulfate transport protein; Provisional; Region: cysT; CHL00187
399742009818	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009819	dimer interface [polypeptide binding]; other site
399742009820	conserved gate region; other site
399742009821	putative PBP binding loops; other site
399742009822	ABC-ATPase subunit interface; other site
399742009823	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
399742009824	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742009825	dimer interface [polypeptide binding]; other site
399742009826	conserved gate region; other site
399742009827	putative PBP binding loops; other site
399742009828	ABC-ATPase subunit interface; other site
399742009829	thiosulfate transporter subunit; Provisional; Region: PRK10852
399742009830	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
399742009831	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
399742009832	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
399742009833	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
399742009834	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
399742009835	putative acetyltransferase; Provisional; Region: PRK03624
399742009836	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742009837	Coenzyme A binding pocket [chemical binding]; other site
399742009838	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
399742009839	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
399742009840	active site
399742009841	metal binding site [ion binding]; metal-binding site
399742009842	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
399742009843	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
399742009844	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
399742009845	Malic enzyme, N-terminal domain; Region: malic; pfam00390
399742009846	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
399742009847	putative NAD(P) binding site [chemical binding]; other site
399742009848	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
399742009849	transaldolase-like protein; Provisional; Region: PTZ00411
399742009850	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
399742009851	active site
399742009852	dimer interface [polypeptide binding]; other site
399742009853	catalytic residue [active]
399742009854	transketolase; Reviewed; Region: PRK12753
399742009855	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
399742009856	TPP-binding site [chemical binding]; other site
399742009857	dimer interface [polypeptide binding]; other site
399742009858	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
399742009859	PYR/PP interface [polypeptide binding]; other site
399742009860	dimer interface [polypeptide binding]; other site
399742009861	TPP binding site [chemical binding]; other site
399742009862	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
399742009863	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
399742009864	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
399742009865	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
399742009866	dimer interface [polypeptide binding]; other site
399742009867	ADP-ribose binding site [chemical binding]; other site
399742009868	active site
399742009869	nudix motif; other site
399742009870	metal binding site [ion binding]; metal-binding site
399742009871	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
399742009872	4Fe-4S binding domain; Region: Fer4; pfam00037
399742009873	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
399742009874	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
399742009875	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742009876	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
399742009877	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
399742009878	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742009879	dimerization interface [polypeptide binding]; other site
399742009880	Histidine kinase; Region: HisKA_3; pfam07730
399742009881	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742009882	ATP binding site [chemical binding]; other site
399742009883	Mg2+ binding site [ion binding]; other site
399742009884	G-X-G motif; other site
399742009885	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
399742009886	Protein export membrane protein; Region: SecD_SecF; cl14618
399742009887	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
399742009888	ArsC family; Region: ArsC; pfam03960
399742009889	putative catalytic residues [active]
399742009890	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
399742009891	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
399742009892	metal binding site [ion binding]; metal-binding site
399742009893	dimer interface [polypeptide binding]; other site
399742009894	hypothetical protein; Provisional; Region: PRK13664
399742009895	putative hydrolase; Provisional; Region: PRK11460
399742009896	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
399742009897	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
399742009898	Helicase; Region: Helicase_RecD; pfam05127
399742009899	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
399742009900	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
399742009901	Predicted metalloprotease [General function prediction only]; Region: COG2321
399742009902	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
399742009903	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
399742009904	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
399742009905	ATP binding site [chemical binding]; other site
399742009906	active site
399742009907	substrate binding site [chemical binding]; other site
399742009908	lipoprotein; Provisional; Region: PRK11679
399742009909	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
399742009910	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
399742009911	dihydrodipicolinate synthase; Region: dapA; TIGR00674
399742009912	dimer interface [polypeptide binding]; other site
399742009913	active site
399742009914	catalytic residue [active]
399742009915	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
399742009916	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
399742009917	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
399742009918	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
399742009919	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
399742009920	catalytic triad [active]
399742009921	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
399742009922	Domain of unknown function DUF20; Region: UPF0118; pfam01594
399742009923	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
399742009924	Peptidase family M48; Region: Peptidase_M48; cl12018
399742009925	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
399742009926	ArsC family; Region: ArsC; pfam03960
399742009927	catalytic residues [active]
399742009928	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
399742009929	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
399742009930	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
399742009931	active site
399742009932	dimer interface [polypeptide binding]; other site
399742009933	catalytic nucleophile [active]
399742009934	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
399742009935	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
399742009936	interface (dimer of trimers) [polypeptide binding]; other site
399742009937	Substrate-binding/catalytic site; other site
399742009938	Zn-binding sites [ion binding]; other site
399742009939	DNA replication initiation factor; Provisional; Region: PRK08084
399742009940	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
399742009941	uracil transporter; Provisional; Region: PRK10720
399742009942	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742009943	active site
399742009944	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
399742009945	beta-galactosidase; Region: BGL; TIGR03356
399742009946	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
399742009947	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
399742009948	dimerization interface [polypeptide binding]; other site
399742009949	putative ATP binding site [chemical binding]; other site
399742009950	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
399742009951	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
399742009952	active site
399742009953	substrate binding site [chemical binding]; other site
399742009954	cosubstrate binding site; other site
399742009955	catalytic site [active]
399742009956	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
399742009957	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
399742009958	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
399742009959	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
399742009960	domain interface [polypeptide binding]; other site
399742009961	active site
399742009962	catalytic site [active]
399742009963	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
399742009964	domain interface [polypeptide binding]; other site
399742009965	active site
399742009966	catalytic site [active]
399742009967	exopolyphosphatase; Provisional; Region: PRK10854
399742009968	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742009969	nucleotide binding site [chemical binding]; other site
399742009970	MASE1; Region: MASE1; pfam05231
399742009971	diguanylate cyclase; Region: GGDEF; smart00267
399742009972	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742009973	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
399742009974	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742009975	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742009976	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
399742009977	dimerization interface [polypeptide binding]; other site
399742009978	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742009979	putative substrate translocation pore; other site
399742009980	Major Facilitator Superfamily; Region: MFS_1; pfam07690
399742009981	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
399742009982	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
399742009983	inhibitor binding site; inhibition site
399742009984	active site
399742009985	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
399742009986	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
399742009987	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
399742009988	GMP synthase; Reviewed; Region: guaA; PRK00074
399742009989	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
399742009990	AMP/PPi binding site [chemical binding]; other site
399742009991	candidate oxyanion hole; other site
399742009992	catalytic triad [active]
399742009993	potential glutamine specificity residues [chemical binding]; other site
399742009994	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
399742009995	ATP Binding subdomain [chemical binding]; other site
399742009996	Ligand Binding sites [chemical binding]; other site
399742009997	Dimerization subdomain; other site
399742009998	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
399742009999	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
399742010000	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
399742010001	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
399742010002	active site
399742010003	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
399742010004	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
399742010005	generic binding surface II; other site
399742010006	generic binding surface I; other site
399742010007	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
399742010008	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
399742010009	Protein of unknown function (DUF796); Region: DUF796; cl01226
399742010010	GTP-binding protein Der; Reviewed; Region: PRK00093
399742010011	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
399742010012	G1 box; other site
399742010013	GTP/Mg2+ binding site [chemical binding]; other site
399742010014	Switch I region; other site
399742010015	G2 box; other site
399742010016	Switch II region; other site
399742010017	G3 box; other site
399742010018	G4 box; other site
399742010019	G5 box; other site
399742010020	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
399742010021	G1 box; other site
399742010022	GTP/Mg2+ binding site [chemical binding]; other site
399742010023	Switch I region; other site
399742010024	G2 box; other site
399742010025	G3 box; other site
399742010026	Switch II region; other site
399742010027	G4 box; other site
399742010028	G5 box; other site
399742010029	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
399742010030	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
399742010031	Trp docking motif [polypeptide binding]; other site
399742010032	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
399742010033	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
399742010034	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
399742010035	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
399742010036	dimer interface [polypeptide binding]; other site
399742010037	motif 1; other site
399742010038	active site
399742010039	motif 2; other site
399742010040	motif 3; other site
399742010041	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
399742010042	anticodon binding site; other site
399742010043	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
399742010044	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
399742010045	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
399742010046	cytoskeletal protein RodZ; Provisional; Region: PRK10856
399742010047	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742010048	non-specific DNA binding site [nucleotide binding]; other site
399742010049	salt bridge; other site
399742010050	sequence-specific DNA binding site [nucleotide binding]; other site
399742010051	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
399742010052	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
399742010053	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742010054	FeS/SAM binding site; other site
399742010055	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
399742010056	active site
399742010057	multimer interface [polypeptide binding]; other site
399742010058	penicillin-binding protein 1C; Provisional; Region: PRK11240
399742010059	Transglycosylase; Region: Transgly; pfam00912
399742010060	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
399742010061	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
399742010062	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
399742010063	MG2 domain; Region: A2M_N; pfam01835
399742010064	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
399742010065	surface patch; other site
399742010066	thioester region; other site
399742010067	specificity defining residues; other site
399742010068	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
399742010069	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742010070	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742010071	active site turn [active]
399742010072	phosphorylation site [posttranslational modification]
399742010073	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
399742010074	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
399742010075	NAD binding site [chemical binding]; other site
399742010076	sugar binding site [chemical binding]; other site
399742010077	divalent metal binding site [ion binding]; other site
399742010078	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742010079	dimer interface [polypeptide binding]; other site
399742010080	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
399742010081	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
399742010082	active site residue [active]
399742010083	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
399742010084	active site residue [active]
399742010085	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
399742010086	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
399742010087	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
399742010088	putative active site [active]
399742010089	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
399742010090	aminopeptidase B; Provisional; Region: PRK05015
399742010091	Peptidase; Region: DUF3663; pfam12404
399742010092	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
399742010093	interface (dimer of trimers) [polypeptide binding]; other site
399742010094	Substrate-binding/catalytic site; other site
399742010095	Zn-binding sites [ion binding]; other site
399742010096	hypothetical protein; Provisional; Region: PRK10721
399742010097	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
399742010098	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
399742010099	catalytic loop [active]
399742010100	iron binding site [ion binding]; other site
399742010101	chaperone protein HscA; Provisional; Region: hscA; PRK05183
399742010102	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
399742010103	nucleotide binding site [chemical binding]; other site
399742010104	putative NEF/HSP70 interaction site [polypeptide binding]; other site
399742010105	SBD interface [polypeptide binding]; other site
399742010106	co-chaperone HscB; Provisional; Region: hscB; PRK05014
399742010107	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
399742010108	HSP70 interaction site [polypeptide binding]; other site
399742010109	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
399742010110	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
399742010111	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
399742010112	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
399742010113	trimerization site [polypeptide binding]; other site
399742010114	active site
399742010115	cysteine desulfurase; Provisional; Region: PRK14012
399742010116	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
399742010117	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
399742010118	catalytic residue [active]
399742010119	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
399742010120	Rrf2 family protein; Region: rrf2_super; TIGR00738
399742010121	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
399742010122	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
399742010123	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
399742010124	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
399742010125	active site
399742010126	dimerization interface [polypeptide binding]; other site
399742010127	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
399742010128	Protein of unknown function (DUF1007); Region: DUF1007; pfam06226
399742010129	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
399742010130	PRD domain; Region: PRD; pfam00874
399742010131	PRD domain; Region: PRD; pfam00874
399742010132	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
399742010133	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010134	putative substrate translocation pore; other site
399742010135	Predicted membrane protein [Function unknown]; Region: COG2259
399742010136	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
399742010137	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
399742010138	dimer interface [polypeptide binding]; other site
399742010139	active site
399742010140	glycine-pyridoxal phosphate binding site [chemical binding]; other site
399742010141	folate binding site [chemical binding]; other site
399742010142	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
399742010143	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
399742010144	heme-binding site [chemical binding]; other site
399742010145	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
399742010146	FAD binding pocket [chemical binding]; other site
399742010147	FAD binding motif [chemical binding]; other site
399742010148	phosphate binding motif [ion binding]; other site
399742010149	beta-alpha-beta structure motif; other site
399742010150	NAD binding pocket [chemical binding]; other site
399742010151	Heme binding  pocket [chemical binding]; other site
399742010152	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
399742010153	Nitrogen regulatory protein P-II; Region: P-II; smart00938
399742010154	response regulator GlrR; Provisional; Region: PRK15115
399742010155	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742010156	active site
399742010157	phosphorylation site [posttranslational modification]
399742010158	intermolecular recognition site; other site
399742010159	dimerization interface [polypeptide binding]; other site
399742010160	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742010161	Walker A motif; other site
399742010162	ATP binding site [chemical binding]; other site
399742010163	Walker B motif; other site
399742010164	arginine finger; other site
399742010165	hypothetical protein; Provisional; Region: PRK10722
399742010166	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
399742010167	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
399742010168	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742010169	dimer interface [polypeptide binding]; other site
399742010170	phosphorylation site [posttranslational modification]
399742010171	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742010172	ATP binding site [chemical binding]; other site
399742010173	Mg2+ binding site [ion binding]; other site
399742010174	G-X-G motif; other site
399742010175	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
399742010176	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
399742010177	dimerization interface [polypeptide binding]; other site
399742010178	ATP binding site [chemical binding]; other site
399742010179	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
399742010180	dimerization interface [polypeptide binding]; other site
399742010181	ATP binding site [chemical binding]; other site
399742010182	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
399742010183	putative active site [active]
399742010184	catalytic triad [active]
399742010185	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
399742010186	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742010187	substrate binding pocket [chemical binding]; other site
399742010188	membrane-bound complex binding site; other site
399742010189	hinge residues; other site
399742010190	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742010191	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742010192	catalytic residue [active]
399742010193	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
399742010194	nucleoside/Zn binding site; other site
399742010195	dimer interface [polypeptide binding]; other site
399742010196	catalytic motif [active]
399742010197	hypothetical protein; Provisional; Region: PRK11590
399742010198	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
399742010199	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
399742010200	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742010201	active site turn [active]
399742010202	phosphorylation site [posttranslational modification]
399742010203	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742010204	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
399742010205	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
399742010206	putative active site [active]
399742010207	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
399742010208	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
399742010209	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
399742010210	putative active site [active]
399742010211	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
399742010212	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
399742010213	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
399742010214	active site
399742010215	hydrophilic channel; other site
399742010216	dimerization interface [polypeptide binding]; other site
399742010217	catalytic residues [active]
399742010218	active site lid [active]
399742010219	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
399742010220	Recombination protein O N terminal; Region: RecO_N; pfam11967
399742010221	Recombination protein O C terminal; Region: RecO_C; pfam02565
399742010222	GTPase Era; Reviewed; Region: era; PRK00089
399742010223	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
399742010224	G1 box; other site
399742010225	GTP/Mg2+ binding site [chemical binding]; other site
399742010226	Switch I region; other site
399742010227	G2 box; other site
399742010228	Switch II region; other site
399742010229	G3 box; other site
399742010230	G4 box; other site
399742010231	G5 box; other site
399742010232	KH domain; Region: KH_2; pfam07650
399742010233	ribonuclease III; Reviewed; Region: rnc; PRK00102
399742010234	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
399742010235	dimerization interface [polypeptide binding]; other site
399742010236	active site
399742010237	metal binding site [ion binding]; metal-binding site
399742010238	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
399742010239	dsRNA binding site [nucleotide binding]; other site
399742010240	signal peptidase I; Provisional; Region: PRK10861
399742010241	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
399742010242	Catalytic site [active]
399742010243	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
399742010244	GTP-binding protein LepA; Provisional; Region: PRK05433
399742010245	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
399742010246	G1 box; other site
399742010247	putative GEF interaction site [polypeptide binding]; other site
399742010248	GTP/Mg2+ binding site [chemical binding]; other site
399742010249	Switch I region; other site
399742010250	G2 box; other site
399742010251	G3 box; other site
399742010252	Switch II region; other site
399742010253	G4 box; other site
399742010254	G5 box; other site
399742010255	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
399742010256	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
399742010257	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
399742010258	SoxR reducing system protein RseC; Provisional; Region: PRK10862
399742010259	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
399742010260	anti-sigma E factor; Provisional; Region: rseB; PRK09455
399742010261	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
399742010262	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
399742010263	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
399742010264	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
399742010265	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742010266	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742010267	DNA binding residues [nucleotide binding]
399742010268	L-aspartate oxidase; Provisional; Region: PRK09077
399742010269	L-aspartate oxidase; Provisional; Region: PRK06175
399742010270	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
399742010271	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
399742010272	Methyltransferase domain; Region: Methyltransf_26; pfam13659
399742010273	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
399742010274	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
399742010275	ATP binding site [chemical binding]; other site
399742010276	Mg++ binding site [ion binding]; other site
399742010277	motif III; other site
399742010278	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742010279	nucleotide binding region [chemical binding]; other site
399742010280	ATP-binding site [chemical binding]; other site
399742010281	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
399742010282	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
399742010283	ligand binding site [chemical binding]; other site
399742010284	active site
399742010285	UGI interface [polypeptide binding]; other site
399742010286	catalytic site [active]
399742010287	putative methyltransferase; Provisional; Region: PRK10864
399742010288	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
399742010289	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
399742010290	thioredoxin 2; Provisional; Region: PRK10996
399742010291	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
399742010292	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
399742010293	catalytic residues [active]
399742010294	Uncharacterized conserved protein [Function unknown]; Region: COG3148
399742010295	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
399742010296	CoA binding domain; Region: CoA_binding_2; pfam13380
399742010297	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
399742010298	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
399742010299	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
399742010300	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
399742010301	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
399742010302	domain interface [polypeptide binding]; other site
399742010303	putative active site [active]
399742010304	catalytic site [active]
399742010305	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
399742010306	domain interface [polypeptide binding]; other site
399742010307	putative active site [active]
399742010308	catalytic site [active]
399742010309	lipoprotein; Provisional; Region: PRK10759
399742010310	protein disaggregation chaperone; Provisional; Region: PRK10865
399742010311	Clp amino terminal domain; Region: Clp_N; pfam02861
399742010312	Clp amino terminal domain; Region: Clp_N; pfam02861
399742010313	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742010314	Walker A motif; other site
399742010315	ATP binding site [chemical binding]; other site
399742010316	Walker B motif; other site
399742010317	arginine finger; other site
399742010318	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742010319	Walker A motif; other site
399742010320	ATP binding site [chemical binding]; other site
399742010321	Walker B motif; other site
399742010322	arginine finger; other site
399742010323	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
399742010324	hypothetical protein; Provisional; Region: PRK10723
399742010325	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
399742010326	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
399742010327	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742010328	RNA binding surface [nucleotide binding]; other site
399742010329	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
399742010330	active site
399742010331	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
399742010332	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
399742010333	30S subunit binding site; other site
399742010334	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
399742010335	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
399742010336	Prephenate dehydratase; Region: PDT; pfam00800
399742010337	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
399742010338	putative L-Phe binding site [chemical binding]; other site
399742010339	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
399742010340	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
399742010341	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
399742010342	prephenate dehydrogenase; Validated; Region: PRK08507
399742010343	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
399742010344	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
399742010345	lipoprotein; Provisional; Region: PRK11443
399742010346	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
399742010347	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
399742010348	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
399742010349	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742010350	metal binding site [ion binding]; metal-binding site
399742010351	active site
399742010352	I-site; other site
399742010353	putative outer membrane lipoprotein; Provisional; Region: PRK09967
399742010354	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
399742010355	ligand binding site [chemical binding]; other site
399742010356	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
399742010357	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
399742010358	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
399742010359	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
399742010360	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
399742010361	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
399742010362	RimM N-terminal domain; Region: RimM; pfam01782
399742010363	PRC-barrel domain; Region: PRC; pfam05239
399742010364	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
399742010365	signal recognition particle protein; Provisional; Region: PRK10867
399742010366	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
399742010367	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
399742010368	P loop; other site
399742010369	GTP binding site [chemical binding]; other site
399742010370	Signal peptide binding domain; Region: SRP_SPB; pfam02978
399742010371	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
399742010372	hypothetical protein; Provisional; Region: PRK11573
399742010373	Domain of unknown function DUF21; Region: DUF21; pfam01595
399742010374	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
399742010375	Transporter associated domain; Region: CorC_HlyC; smart01091
399742010376	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
399742010377	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
399742010378	dimer interface [polypeptide binding]; other site
399742010379	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
399742010380	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
399742010381	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
399742010382	recombination and repair protein; Provisional; Region: PRK10869
399742010383	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
399742010384	Walker A/P-loop; other site
399742010385	ATP binding site [chemical binding]; other site
399742010386	Q-loop/lid; other site
399742010387	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
399742010388	ABC transporter signature motif; other site
399742010389	Walker B; other site
399742010390	D-loop; other site
399742010391	H-loop/switch region; other site
399742010392	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
399742010393	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
399742010394	hypothetical protein; Validated; Region: PRK01777
399742010395	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
399742010396	putative coenzyme Q binding site [chemical binding]; other site
399742010397	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
399742010398	SmpB-tmRNA interface; other site
399742010399	integrase; Provisional; Region: PRK09692
399742010400	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
399742010401	active site
399742010402	Int/Topo IB signature motif; other site
399742010403	AAA domain; Region: AAA_21; pfam13304
399742010404	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
399742010405	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
399742010406	putative active site [active]
399742010407	putative metal-binding site [ion binding]; other site
399742010408	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
399742010409	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
399742010410	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
399742010411	Ash protein family; Region: Phage_ASH; pfam10554
399742010412	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
399742010413	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
399742010414	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
399742010415	active site
399742010416	metal binding site [ion binding]; metal-binding site
399742010417	D5 N terminal like; Region: D5_N; smart00885
399742010418	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
399742010419	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
399742010420	Serine/threonine protein kinase involved in cell cycle control [Signal transduction mechanisms / Cell division and chromosome partitioning]; Region: RIO1; COG1718
399742010421	RIO kinase family; RIO1, RIO3 and similar proteins, catalytic domain. The RIO kinase catalytic domain family is part of a larger superfamily, that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; Region: RIO1_like; cd05145
399742010422	ATP binding site [chemical binding]; other site
399742010423	YceI-like domain; Region: YceI; pfam04264
399742010424	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
399742010425	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742010426	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742010427	DNA binding residues [nucleotide binding]
399742010428	Pectate lyase; Region: Pectate_lyase; pfam03211
399742010429	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742010430	binding surface
399742010431	TPR motif; other site
399742010432	Tetratricopeptide repeat; Region: TPR_16; pfam13432
399742010433	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010434	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010435	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010436	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010437	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010438	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010439	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010440	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010441	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
399742010442	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010443	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
399742010444	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
399742010445	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
399742010446	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
399742010447	putative active site [active]
399742010448	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
399742010449	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
399742010450	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742010451	Walker A/P-loop; other site
399742010452	ATP binding site [chemical binding]; other site
399742010453	Q-loop/lid; other site
399742010454	ABC transporter signature motif; other site
399742010455	Walker B; other site
399742010456	D-loop; other site
399742010457	H-loop/switch region; other site
399742010458	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
399742010459	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742010460	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742010461	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
399742010462	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
399742010463	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
399742010464	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742010465	homodimer interface [polypeptide binding]; other site
399742010466	catalytic residue [active]
399742010467	General stress protein [General function prediction only]; Region: GsiB; COG3729
399742010468	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
399742010469	dimerization interface [polypeptide binding]; other site
399742010470	metal binding site [ion binding]; metal-binding site
399742010471	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
399742010472	dinuclear metal binding motif [ion binding]; other site
399742010473	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
399742010474	dimanganese center [ion binding]; other site
399742010475	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
399742010476	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
399742010477	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
399742010478	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
399742010479	hypothetical protein; Validated; Region: PRK03657
399742010480	Predicted membrane protein [Function unknown]; Region: COG2323
399742010481	hypothetical protein; Provisional; Region: PRK10053
399742010482	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
399742010483	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742010484	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742010485	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_8; cd08477
399742010486	putative effector binding pocket; other site
399742010487	putative dimerization interface [polypeptide binding]; other site
399742010488	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
399742010489	putative NAD(P) binding site [chemical binding]; other site
399742010490	homodimer interface [polypeptide binding]; other site
399742010491	Methyltransferase domain; Region: Methyltransf_31; pfam13847
399742010492	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742010493	S-adenosylmethionine binding site [chemical binding]; other site
399742010494	putative deaminase; Validated; Region: PRK06846
399742010495	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
399742010496	active site
399742010497	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
399742010498	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
399742010499	putative substrate binding site [chemical binding]; other site
399742010500	nucleotide binding site [chemical binding]; other site
399742010501	nucleotide binding site [chemical binding]; other site
399742010502	homodimer interface [polypeptide binding]; other site
399742010503	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
399742010504	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
399742010505	CoA binding domain; Region: CoA_binding; pfam02629
399742010506	CoA-ligase; Region: Ligase_CoA; pfam00549
399742010507	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
399742010508	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
399742010509	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
399742010510	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
399742010511	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742010512	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742010513	dimerization interface [polypeptide binding]; other site
399742010514	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
399742010515	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
399742010516	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
399742010517	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
399742010518	hypothetical protein; Provisional; Region: PRK10556
399742010519	hypothetical protein; Provisional; Region: PRK10132
399742010520	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
399742010521	catalytic residues [active]
399742010522	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
399742010523	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
399742010524	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
399742010525	Class I ribonucleotide reductase; Region: RNR_I; cd01679
399742010526	active site
399742010527	dimer interface [polypeptide binding]; other site
399742010528	catalytic residues [active]
399742010529	effector binding site; other site
399742010530	R2 peptide binding site; other site
399742010531	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
399742010532	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
399742010533	dimer interface [polypeptide binding]; other site
399742010534	putative radical transfer pathway; other site
399742010535	diiron center [ion binding]; other site
399742010536	tyrosyl radical; other site
399742010537	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
399742010538	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
399742010539	Walker A/P-loop; other site
399742010540	ATP binding site [chemical binding]; other site
399742010541	Q-loop/lid; other site
399742010542	ABC transporter signature motif; other site
399742010543	Walker B; other site
399742010544	D-loop; other site
399742010545	H-loop/switch region; other site
399742010546	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
399742010547	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
399742010548	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742010549	dimer interface [polypeptide binding]; other site
399742010550	conserved gate region; other site
399742010551	putative PBP binding loops; other site
399742010552	ABC-ATPase subunit interface; other site
399742010553	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
399742010554	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
399742010555	Helix-turn-helix domain; Region: HTH_28; pfam13518
399742010556	putative transposase OrfB; Reviewed; Region: PHA02517
399742010557	Homeodomain-like domain; Region: HTH_32; pfam13565
399742010558	Integrase core domain; Region: rve; pfam00665
399742010559	Integrase core domain; Region: rve_3; pfam13683
399742010560	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
399742010561	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010562	transcriptional repressor MprA; Provisional; Region: PRK10870
399742010563	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
399742010564	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
399742010565	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742010566	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742010567	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
399742010568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010569	putative substrate translocation pore; other site
399742010570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010571	2-isopropylmalate synthase; Validated; Region: PRK03739
399742010572	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
399742010573	active site
399742010574	catalytic residues [active]
399742010575	metal binding site [ion binding]; metal-binding site
399742010576	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
399742010577	Cupin domain; Region: Cupin_2; pfam07883
399742010578	Helix-turn-helix domain; Region: HTH_18; pfam12833
399742010579	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742010580	S-ribosylhomocysteinase; Provisional; Region: PRK02260
399742010581	glutamate--cysteine ligase; Provisional; Region: PRK02107
399742010582	Predicted membrane protein [Function unknown]; Region: COG1238
399742010583	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
399742010584	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742010585	motif II; other site
399742010586	carbon storage regulator; Provisional; Region: PRK01712
399742010587	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
399742010588	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
399742010589	motif 1; other site
399742010590	active site
399742010591	motif 2; other site
399742010592	motif 3; other site
399742010593	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
399742010594	DHHA1 domain; Region: DHHA1; pfam02272
399742010595	recombination regulator RecX; Reviewed; Region: recX; PRK00117
399742010596	recombinase A; Provisional; Region: recA; PRK09354
399742010597	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
399742010598	hexamer interface [polypeptide binding]; other site
399742010599	Walker A motif; other site
399742010600	ATP binding site [chemical binding]; other site
399742010601	Walker B motif; other site
399742010602	hypothetical protein; Validated; Region: PRK03661
399742010603	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
399742010604	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
399742010605	metal binding site [ion binding]; metal-binding site
399742010606	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
399742010607	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742010608	ABC-ATPase subunit  interface; other site
399742010609	dimer interface [polypeptide binding]; other site
399742010610	putative PBP binding regions; other site
399742010611	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
399742010612	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
399742010613	Transglycosylase SLT domain; Region: SLT_2; pfam13406
399742010614	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742010615	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742010616	catalytic residue [active]
399742010617	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
399742010618	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
399742010619	putative active site [active]
399742010620	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
399742010621	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
399742010622	GAF domain; Region: GAF; pfam01590
399742010623	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742010624	Walker A motif; other site
399742010625	ATP binding site [chemical binding]; other site
399742010626	Walker B motif; other site
399742010627	arginine finger; other site
399742010628	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
399742010629	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
399742010630	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
399742010631	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
399742010632	iron binding site [ion binding]; other site
399742010633	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
399742010634	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742010635	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
399742010636	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
399742010637	Acylphosphatase; Region: Acylphosphatase; pfam00708
399742010638	HypF finger; Region: zf-HYPF; pfam07503
399742010639	HypF finger; Region: zf-HYPF; pfam07503
399742010640	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
399742010641	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
399742010642	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
399742010643	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742010644	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742010645	DNA binding site [nucleotide binding]
399742010646	domain linker motif; other site
399742010647	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
399742010648	dimerization interface (closed form) [polypeptide binding]; other site
399742010649	ligand binding site [chemical binding]; other site
399742010650	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
399742010651	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742010652	active site turn [active]
399742010653	phosphorylation site [posttranslational modification]
399742010654	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
399742010655	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
399742010656	beta-galactosidase; Region: BGL; TIGR03356
399742010657	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
399742010658	nickel binding site [ion binding]; other site
399742010659	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
399742010660	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
399742010661	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
399742010662	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
399742010663	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
399742010664	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
399742010665	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
399742010666	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
399742010667	NADH dehydrogenase; Region: NADHdh; cl00469
399742010668	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
399742010669	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
399742010670	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
399742010671	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
399742010672	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
399742010673	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
399742010674	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
399742010675	hydrogenase assembly chaperone; Provisional; Region: PRK10409
399742010676	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
399742010677	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
399742010678	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
399742010679	dimerization interface [polypeptide binding]; other site
399742010680	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
399742010681	ATP binding site [chemical binding]; other site
399742010682	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
399742010683	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
399742010684	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
399742010685	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742010686	Walker A motif; other site
399742010687	ATP binding site [chemical binding]; other site
399742010688	Walker B motif; other site
399742010689	arginine finger; other site
399742010690	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
399742010691	Metal binding protein TroA_a.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148
399742010692	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
399742010693	putative ligand binding residues [chemical binding]; other site
399742010694	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
399742010695	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742010696	dimer interface [polypeptide binding]; other site
399742010697	putative PBP binding regions; other site
399742010698	ABC-ATPase subunit  interface; other site
399742010699	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
399742010700	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742010701	Walker A/P-loop; other site
399742010702	ATP binding site [chemical binding]; other site
399742010703	Q-loop/lid; other site
399742010704	ABC transporter signature motif; other site
399742010705	Walker B; other site
399742010706	D-loop; other site
399742010707	H-loop/switch region; other site
399742010708	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010709	putative substrate translocation pore; other site
399742010710	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
399742010711	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
399742010712	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
399742010713	MutS domain I; Region: MutS_I; pfam01624
399742010714	MutS domain II; Region: MutS_II; pfam05188
399742010715	MutS domain III; Region: MutS_III; pfam05192
399742010716	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
399742010717	Walker A/P-loop; other site
399742010718	ATP binding site [chemical binding]; other site
399742010719	Q-loop/lid; other site
399742010720	ABC transporter signature motif; other site
399742010721	Walker B; other site
399742010722	D-loop; other site
399742010723	H-loop/switch region; other site
399742010724	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
399742010725	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
399742010726	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742010727	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
399742010728	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742010729	DNA binding residues [nucleotide binding]
399742010730	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
399742010731	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742010732	Peptidase family M23; Region: Peptidase_M23; pfam01551
399742010733	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
399742010734	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742010735	S-adenosylmethionine binding site [chemical binding]; other site
399742010736	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
399742010737	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
399742010738	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
399742010739	Permutation of conserved domain; other site
399742010740	active site
399742010741	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
399742010742	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
399742010743	homotrimer interaction site [polypeptide binding]; other site
399742010744	zinc binding site [ion binding]; other site
399742010745	CDP-binding sites; other site
399742010746	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
399742010747	substrate binding site; other site
399742010748	dimer interface; other site
399742010749	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
399742010750	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
399742010751	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
399742010752	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
399742010753	ligand-binding site [chemical binding]; other site
399742010754	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
399742010755	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
399742010756	CysD dimerization site [polypeptide binding]; other site
399742010757	G1 box; other site
399742010758	putative GEF interaction site [polypeptide binding]; other site
399742010759	GTP/Mg2+ binding site [chemical binding]; other site
399742010760	Switch I region; other site
399742010761	G2 box; other site
399742010762	G3 box; other site
399742010763	Switch II region; other site
399742010764	G4 box; other site
399742010765	G5 box; other site
399742010766	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
399742010767	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
399742010768	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
399742010769	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
399742010770	Active Sites [active]
399742010771	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
399742010772	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
399742010773	metal binding site [ion binding]; metal-binding site
399742010774	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
399742010775	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
399742010776	Active Sites [active]
399742010777	sulfite reductase subunit beta; Provisional; Region: PRK13504
399742010778	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
399742010779	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
399742010780	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
399742010781	Flavodoxin; Region: Flavodoxin_1; pfam00258
399742010782	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
399742010783	FAD binding pocket [chemical binding]; other site
399742010784	FAD binding motif [chemical binding]; other site
399742010785	catalytic residues [active]
399742010786	NAD binding pocket [chemical binding]; other site
399742010787	phosphate binding motif [ion binding]; other site
399742010788	beta-alpha-beta structure motif; other site
399742010789	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
399742010790	active site
399742010791	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
399742010792	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
399742010793	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
399742010794	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
399742010795	putative active site cavity [active]
399742010796	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
399742010797	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742010798	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742010799	active site turn [active]
399742010800	phosphorylation site [posttranslational modification]
399742010801	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
399742010802	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
399742010803	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
399742010804	putative active site [active]
399742010805	enolase; Provisional; Region: eno; PRK00077
399742010806	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
399742010807	dimer interface [polypeptide binding]; other site
399742010808	metal binding site [ion binding]; metal-binding site
399742010809	substrate binding pocket [chemical binding]; other site
399742010810	CTP synthetase; Validated; Region: pyrG; PRK05380
399742010811	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
399742010812	Catalytic site [active]
399742010813	active site
399742010814	UTP binding site [chemical binding]; other site
399742010815	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
399742010816	active site
399742010817	putative oxyanion hole; other site
399742010818	catalytic triad [active]
399742010819	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
399742010820	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
399742010821	homodimer interface [polypeptide binding]; other site
399742010822	metal binding site [ion binding]; metal-binding site
399742010823	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
399742010824	homodimer interface [polypeptide binding]; other site
399742010825	active site
399742010826	putative chemical substrate binding site [chemical binding]; other site
399742010827	metal binding site [ion binding]; metal-binding site
399742010828	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
399742010829	HD domain; Region: HD_4; pfam13328
399742010830	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
399742010831	synthetase active site [active]
399742010832	NTP binding site [chemical binding]; other site
399742010833	metal binding site [ion binding]; metal-binding site
399742010834	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
399742010835	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
399742010836	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
399742010837	TRAM domain; Region: TRAM; pfam01938
399742010838	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742010839	S-adenosylmethionine binding site [chemical binding]; other site
399742010840	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
399742010841	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
399742010842	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742010843	dimerization interface [polypeptide binding]; other site
399742010844	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742010845	dimer interface [polypeptide binding]; other site
399742010846	phosphorylation site [posttranslational modification]
399742010847	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742010848	ATP binding site [chemical binding]; other site
399742010849	Mg2+ binding site [ion binding]; other site
399742010850	G-X-G motif; other site
399742010851	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
399742010852	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742010853	active site
399742010854	phosphorylation site [posttranslational modification]
399742010855	intermolecular recognition site; other site
399742010856	dimerization interface [polypeptide binding]; other site
399742010857	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
399742010858	putative binding surface; other site
399742010859	active site
399742010860	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
399742010861	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
399742010862	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
399742010863	active site
399742010864	tetramer interface [polypeptide binding]; other site
399742010865	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
399742010866	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
399742010867	active site
399742010868	tetramer interface [polypeptide binding]; other site
399742010869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010870	D-galactonate transporter; Region: 2A0114; TIGR00893
399742010871	putative substrate translocation pore; other site
399742010872	flavodoxin; Provisional; Region: PRK08105
399742010873	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
399742010874	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
399742010875	probable active site [active]
399742010876	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
399742010877	SecY interacting protein Syd; Provisional; Region: PRK04968
399742010878	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
399742010879	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
399742010880	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
399742010881	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
399742010882	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
399742010883	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
399742010884	serine transporter; Region: stp; TIGR00814
399742010885	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
399742010886	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
399742010887	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
399742010888	flap endonuclease-like protein; Provisional; Region: PRK09482
399742010889	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
399742010890	active site
399742010891	metal binding site 1 [ion binding]; metal-binding site
399742010892	putative 5' ssDNA interaction site; other site
399742010893	metal binding site 3; metal-binding site
399742010894	metal binding site 2 [ion binding]; metal-binding site
399742010895	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
399742010896	putative DNA binding site [nucleotide binding]; other site
399742010897	putative metal binding site [ion binding]; other site
399742010898	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
399742010899	FtsJ-like methyltransferase; Region: FtsJ; cl17430
399742010900	hypothetical protein; Provisional; Region: PRK10873
399742010901	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
399742010902	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742010903	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
399742010904	dimerization interface [polypeptide binding]; other site
399742010905	substrate binding pocket [chemical binding]; other site
399742010906	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
399742010907	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
399742010908	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
399742010909	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
399742010910	catalytic residue [active]
399742010911	Fe-S metabolism associated domain; Region: SufE; cl00951
399742010912	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
399742010913	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
399742010914	putative ATP binding site [chemical binding]; other site
399742010915	putative substrate interface [chemical binding]; other site
399742010916	murein transglycosylase A; Provisional; Region: mltA; PRK11162
399742010917	MltA specific insert domain; Region: MltA; smart00925
399742010918	3D domain; Region: 3D; pfam06725
399742010919	AMIN domain; Region: AMIN; pfam11741
399742010920	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
399742010921	active site
399742010922	metal binding site [ion binding]; metal-binding site
399742010923	N-acetylglutamate synthase; Validated; Region: PRK05279
399742010924	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
399742010925	putative feedback inhibition sensing region; other site
399742010926	putative nucleotide binding site [chemical binding]; other site
399742010927	putative substrate binding site [chemical binding]; other site
399742010928	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742010929	Coenzyme A binding pocket [chemical binding]; other site
399742010930	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
399742010931	AAA domain; Region: AAA_30; pfam13604
399742010932	Family description; Region: UvrD_C_2; pfam13538
399742010933	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
399742010934	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
399742010935	protease3; Provisional; Region: PRK15101
399742010936	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
399742010937	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
399742010938	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
399742010939	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
399742010940	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
399742010941	hypothetical protein; Provisional; Region: PRK10332
399742010942	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
399742010943	hypothetical protein; Provisional; Region: PRK10557
399742010944	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
399742010945	hypothetical protein; Provisional; Region: PRK10506
399742010946	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
399742010947	thymidylate synthase; Reviewed; Region: thyA; PRK01827
399742010948	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
399742010949	dimerization interface [polypeptide binding]; other site
399742010950	active site
399742010951	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
399742010952	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
399742010953	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
399742010954	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
399742010955	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
399742010956	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
399742010957	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
399742010958	putative active site [active]
399742010959	Ap4A binding site [chemical binding]; other site
399742010960	nudix motif; other site
399742010961	putative metal binding site [ion binding]; other site
399742010962	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
399742010963	putative DNA-binding cleft [nucleotide binding]; other site
399742010964	putative DNA clevage site; other site
399742010965	molecular lever; other site
399742010966	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
399742010967	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742010968	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742010969	active site
399742010970	catalytic tetrad [active]
399742010971	lysophospholipid transporter LplT; Provisional; Region: PRK11195
399742010972	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742010973	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
399742010974	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
399742010975	putative acyl-acceptor binding pocket; other site
399742010976	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
399742010977	acyl-activating enzyme (AAE) consensus motif; other site
399742010978	putative AMP binding site [chemical binding]; other site
399742010979	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
399742010980	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742010981	DNA binding site [nucleotide binding]
399742010982	domain linker motif; other site
399742010983	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
399742010984	dimerization interface (closed form) [polypeptide binding]; other site
399742010985	ligand binding site [chemical binding]; other site
399742010986	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742010987	Coenzyme A binding pocket [chemical binding]; other site
399742010988	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
399742010989	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742010990	DNA-binding site [nucleotide binding]; DNA binding site
399742010991	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
399742010992	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
399742010993	beta-galactosidase; Region: BGL; TIGR03356
399742010994	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
399742010995	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
399742010996	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742010997	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742010998	DNA binding site [nucleotide binding]
399742010999	domain linker motif; other site
399742011000	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
399742011001	dimerization interface (closed form) [polypeptide binding]; other site
399742011002	ligand binding site [chemical binding]; other site
399742011003	diaminopimelate decarboxylase; Provisional; Region: PRK11165
399742011004	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
399742011005	active site
399742011006	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
399742011007	substrate binding site [chemical binding]; other site
399742011008	catalytic residues [active]
399742011009	dimer interface [polypeptide binding]; other site
399742011010	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
399742011011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742011012	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
399742011013	putative dimerization interface [polypeptide binding]; other site
399742011014	putative racemase; Provisional; Region: PRK10200
399742011015	aspartate racemase; Region: asp_race; TIGR00035
399742011016	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
399742011017	Helix-turn-helix domain; Region: HTH_28; pfam13518
399742011018	putative transposase OrfB; Reviewed; Region: PHA02517
399742011019	Homeodomain-like domain; Region: HTH_32; pfam13565
399742011020	Integrase core domain; Region: rve; pfam00665
399742011021	Integrase core domain; Region: rve_3; pfam13683
399742011022	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742011023	dimer interface [polypeptide binding]; other site
399742011024	conserved gate region; other site
399742011025	putative PBP binding loops; other site
399742011026	ABC-ATPase subunit interface; other site
399742011027	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
399742011028	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742011029	dimer interface [polypeptide binding]; other site
399742011030	conserved gate region; other site
399742011031	putative PBP binding loops; other site
399742011032	ABC-ATPase subunit interface; other site
399742011033	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
399742011034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742011035	Walker A/P-loop; other site
399742011036	ATP binding site [chemical binding]; other site
399742011037	Q-loop/lid; other site
399742011038	ABC transporter signature motif; other site
399742011039	Walker B; other site
399742011040	D-loop; other site
399742011041	H-loop/switch region; other site
399742011042	TOBE domain; Region: TOBE; cl01440
399742011043	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
399742011044	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
399742011045	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
399742011046	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
399742011047	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
399742011048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011049	putative substrate translocation pore; other site
399742011050	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011051	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
399742011052	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
399742011053	NADP binding site [chemical binding]; other site
399742011054	homodimer interface [polypeptide binding]; other site
399742011055	active site
399742011056	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
399742011057	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
399742011058	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
399742011059	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
399742011060	putative acyltransferase; Provisional; Region: PRK05790
399742011061	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
399742011062	dimer interface [polypeptide binding]; other site
399742011063	active site
399742011064	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742011065	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742011066	LysR substrate binding domain; Region: LysR_substrate; pfam03466
399742011067	dimerization interface [polypeptide binding]; other site
399742011068	Predicted membrane protein [Function unknown]; Region: COG4125
399742011069	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
399742011070	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
399742011071	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
399742011072	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
399742011073	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
399742011074	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
399742011075	Predicted acetyltransferase [General function prediction only]; Region: COG2388
399742011076	Uncharacterized conserved protein [Function unknown]; Region: COG3592
399742011077	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
399742011078	Peptidase family M23; Region: Peptidase_M23; pfam01551
399742011079	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
399742011080	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
399742011081	active site
399742011082	metal binding site [ion binding]; metal-binding site
399742011083	nudix motif; other site
399742011084	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
399742011085	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
399742011086	dimer interface [polypeptide binding]; other site
399742011087	putative anticodon binding site; other site
399742011088	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
399742011089	motif 1; other site
399742011090	active site
399742011091	motif 2; other site
399742011092	motif 3; other site
399742011093	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
399742011094	DHH family; Region: DHH; pfam01368
399742011095	DHHA1 domain; Region: DHHA1; pfam02272
399742011096	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
399742011097	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
399742011098	dimerization domain [polypeptide binding]; other site
399742011099	dimer interface [polypeptide binding]; other site
399742011100	catalytic residues [active]
399742011101	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
399742011102	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
399742011103	active site
399742011104	Int/Topo IB signature motif; other site
399742011105	flavodoxin FldB; Provisional; Region: PRK12359
399742011106	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
399742011107	hypothetical protein; Provisional; Region: PRK10878
399742011108	putative global regulator; Reviewed; Region: PRK09559
399742011109	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
399742011110	hemolysin; Provisional; Region: PRK15087
399742011111	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
399742011112	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
399742011113	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
399742011114	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
399742011115	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
399742011116	putative active site [active]
399742011117	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
399742011118	beta-galactosidase; Region: BGL; TIGR03356
399742011119	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
399742011120	classical (c) SDRs; Region: SDR_c; cd05233
399742011121	NAD(P) binding site [chemical binding]; other site
399742011122	active site
399742011123	glycine dehydrogenase; Provisional; Region: PRK05367
399742011124	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
399742011125	tetramer interface [polypeptide binding]; other site
399742011126	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742011127	catalytic residue [active]
399742011128	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
399742011129	tetramer interface [polypeptide binding]; other site
399742011130	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742011131	catalytic residue [active]
399742011132	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
399742011133	lipoyl attachment site [posttranslational modification]; other site
399742011134	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
399742011135	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
399742011136	oxidoreductase; Provisional; Region: PRK08013
399742011137	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
399742011138	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
399742011139	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
399742011140	proline aminopeptidase P II; Provisional; Region: PRK10879
399742011141	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
399742011142	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
399742011143	active site
399742011144	hypothetical protein; Reviewed; Region: PRK01736
399742011145	Z-ring-associated protein; Provisional; Region: PRK10972
399742011146	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
399742011147	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
399742011148	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
399742011149	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
399742011150	ligand binding site [chemical binding]; other site
399742011151	NAD binding site [chemical binding]; other site
399742011152	tetramer interface [polypeptide binding]; other site
399742011153	catalytic site [active]
399742011154	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
399742011155	L-serine binding site [chemical binding]; other site
399742011156	ACT domain interface; other site
399742011157	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
399742011158	tetramer (dimer of dimers) interface [polypeptide binding]; other site
399742011159	active site
399742011160	dimer interface [polypeptide binding]; other site
399742011161	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
399742011162	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742011163	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
399742011164	putative dimerization interface [polypeptide binding]; other site
399742011165	Uncharacterized conserved protein [Function unknown]; Region: COG2968
399742011166	oxidative stress defense protein; Provisional; Region: PRK11087
399742011167	arginine exporter protein; Provisional; Region: PRK09304
399742011168	mechanosensitive channel MscS; Provisional; Region: PRK10334
399742011169	Mechanosensitive ion channel; Region: MS_channel; pfam00924
399742011170	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
399742011171	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
399742011172	active site
399742011173	intersubunit interface [polypeptide binding]; other site
399742011174	zinc binding site [ion binding]; other site
399742011175	Na+ binding site [ion binding]; other site
399742011176	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
399742011177	Phosphoglycerate kinase; Region: PGK; pfam00162
399742011178	substrate binding site [chemical binding]; other site
399742011179	hinge regions; other site
399742011180	ADP binding site [chemical binding]; other site
399742011181	catalytic site [active]
399742011182	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
399742011183	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
399742011184	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
399742011185	transketolase; Reviewed; Region: PRK12753
399742011186	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
399742011187	TPP-binding site [chemical binding]; other site
399742011188	dimer interface [polypeptide binding]; other site
399742011189	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
399742011190	PYR/PP interface [polypeptide binding]; other site
399742011191	dimer interface [polypeptide binding]; other site
399742011192	TPP binding site [chemical binding]; other site
399742011193	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
399742011194	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
399742011195	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
399742011196	agmatinase; Region: agmatinase; TIGR01230
399742011197	oligomer interface [polypeptide binding]; other site
399742011198	putative active site [active]
399742011199	Mn binding site [ion binding]; other site
399742011200	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
399742011201	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
399742011202	dimer interface [polypeptide binding]; other site
399742011203	active site
399742011204	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
399742011205	catalytic residues [active]
399742011206	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
399742011207	S-adenosylmethionine synthetase; Validated; Region: PRK05250
399742011208	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
399742011209	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
399742011210	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
399742011211	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
399742011212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011213	putative substrate translocation pore; other site
399742011214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011215	hypothetical protein; Provisional; Region: PRK04860
399742011216	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
399742011217	DNA-specific endonuclease I; Provisional; Region: PRK15137
399742011218	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
399742011219	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
399742011220	RNA methyltransferase, RsmE family; Region: TIGR00046
399742011221	glutathione synthetase; Provisional; Region: PRK05246
399742011222	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
399742011223	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
399742011224	hypothetical protein; Validated; Region: PRK00228
399742011225	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
399742011226	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
399742011227	Transcriptional regulator [Transcription]; Region: IclR; COG1414
399742011228	Bacterial transcriptional regulator; Region: IclR; pfam01614
399742011229	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
399742011230	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
399742011231	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
399742011232	Walker A motif; other site
399742011233	ATP binding site [chemical binding]; other site
399742011234	Walker B motif; other site
399742011235	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
399742011236	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
399742011237	catalytic residue [active]
399742011238	YGGT family; Region: YGGT; pfam02325
399742011239	Predicted integral membrane protein [Function unknown]; Region: COG0762
399742011240	hypothetical protein; Validated; Region: PRK05090
399742011241	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
399742011242	active site
399742011243	dimerization interface [polypeptide binding]; other site
399742011244	HemN family oxidoreductase; Provisional; Region: PRK05660
399742011245	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742011246	FeS/SAM binding site; other site
399742011247	HemN C-terminal domain; Region: HemN_C; pfam06969
399742011248	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
399742011249	putative active site [active]
399742011250	hypothetical protein; Provisional; Region: PRK10626
399742011251	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
399742011252	hypothetical protein; Provisional; Region: PRK11702
399742011253	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
399742011254	adenine DNA glycosylase; Provisional; Region: PRK10880
399742011255	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
399742011256	minor groove reading motif; other site
399742011257	helix-hairpin-helix signature motif; other site
399742011258	substrate binding pocket [chemical binding]; other site
399742011259	active site
399742011260	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
399742011261	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
399742011262	DNA binding and oxoG recognition site [nucleotide binding]
399742011263	oxidative damage protection protein; Provisional; Region: PRK05408
399742011264	murein transglycosylase C; Provisional; Region: mltC; PRK11671
399742011265	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
399742011266	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
399742011267	N-acetyl-D-glucosamine binding site [chemical binding]; other site
399742011268	catalytic residue [active]
399742011269	nucleoside transporter; Region: 2A0110; TIGR00889
399742011270	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
399742011271	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
399742011272	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
399742011273	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
399742011274	citrate lyase subunit gamma; Provisional; Region: PRK13253
399742011275	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
399742011276	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
399742011277	putative active site [active]
399742011278	(T/H)XGH motif; other site
399742011279	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
399742011280	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
399742011281	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
399742011282	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
399742011283	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742011284	putative active site [active]
399742011285	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742011286	ATP binding site [chemical binding]; other site
399742011287	Mg2+ binding site [ion binding]; other site
399742011288	G-X-G motif; other site
399742011289	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
399742011290	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742011291	active site
399742011292	phosphorylation site [posttranslational modification]
399742011293	intermolecular recognition site; other site
399742011294	dimerization interface [polypeptide binding]; other site
399742011295	Transcriptional regulator; Region: CitT; pfam12431
399742011296	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
399742011297	ornithine decarboxylase; Provisional; Region: PRK13578
399742011298	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
399742011299	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
399742011300	homodimer interface [polypeptide binding]; other site
399742011301	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742011302	catalytic residue [active]
399742011303	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
399742011304	Protein of unknown function (DUF554); Region: DUF554; pfam04474
399742011305	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
399742011306	Autotransporter beta-domain; Region: Autotransporter; pfam03797
399742011307	hypothetical protein; Provisional; Region: PRK09867
399742011308	HNH endonuclease; Region: HNH_2; pfam13391
399742011309	RNA polymerase sigma factor; Provisional; Region: PRK12512
399742011310	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742011311	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742011312	DNA binding residues [nucleotide binding]
399742011313	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
399742011314	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
399742011315	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
399742011316	catalytic triad [active]
399742011317	YfaZ precursor; Region: YfaZ; pfam07437
399742011318	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
399742011319	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
399742011320	CHAP domain; Region: CHAP; pfam05257
399742011321	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
399742011322	putative S-transferase; Provisional; Region: PRK11752
399742011323	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
399742011324	C-terminal domain interface [polypeptide binding]; other site
399742011325	GSH binding site (G-site) [chemical binding]; other site
399742011326	dimer interface [polypeptide binding]; other site
399742011327	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
399742011328	dimer interface [polypeptide binding]; other site
399742011329	N-terminal domain interface [polypeptide binding]; other site
399742011330	active site
399742011331	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
399742011332	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
399742011333	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
399742011334	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
399742011335	putative ligand binding residues [chemical binding]; other site
399742011336	Conserved TM helix; Region: TM_helix; pfam05552
399742011337	mechanosensitive channel MscS; Provisional; Region: PRK10334
399742011338	Mechanosensitive ion channel; Region: MS_channel; pfam00924
399742011339	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
399742011340	Domain of unknown function DUF20; Region: UPF0118; pfam01594
399742011341	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742011342	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742011343	DNA binding residues [nucleotide binding]
399742011344	dimerization interface [polypeptide binding]; other site
399742011345	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
399742011346	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
399742011347	DNA binding residues [nucleotide binding]
399742011348	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
399742011349	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742011350	PAS fold; Region: PAS_3; pfam08447
399742011351	putative active site [active]
399742011352	heme pocket [chemical binding]; other site
399742011353	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742011354	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742011355	metal binding site [ion binding]; metal-binding site
399742011356	active site
399742011357	I-site; other site
399742011358	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
399742011359	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
399742011360	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
399742011361	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
399742011362	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
399742011363	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742011364	dimerization interface [polypeptide binding]; other site
399742011365	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742011366	dimer interface [polypeptide binding]; other site
399742011367	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
399742011368	putative CheW interface [polypeptide binding]; other site
399742011369	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
399742011370	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
399742011371	Autotransporter beta-domain; Region: Autotransporter; smart00869
399742011372	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
399742011373	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
399742011374	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742011375	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742011376	active site
399742011377	catalytic tetrad [active]
399742011378	hypothetical protein; Provisional; Region: PRK05208
399742011379	oxidoreductase; Provisional; Region: PRK07985
399742011380	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
399742011381	NAD binding site [chemical binding]; other site
399742011382	metal binding site [ion binding]; metal-binding site
399742011383	active site
399742011384	biopolymer transport protein ExbD; Provisional; Region: PRK11267
399742011385	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
399742011386	biopolymer transport protein ExbB; Provisional; Region: PRK10414
399742011387	cystathionine beta-lyase; Provisional; Region: PRK08114
399742011388	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
399742011389	homodimer interface [polypeptide binding]; other site
399742011390	substrate-cofactor binding pocket; other site
399742011391	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742011392	catalytic residue [active]
399742011393	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
399742011394	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
399742011395	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
399742011396	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742011397	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742011398	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742011399	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
399742011400	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
399742011401	dimer interface [polypeptide binding]; other site
399742011402	active site
399742011403	metal binding site [ion binding]; metal-binding site
399742011404	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
399742011405	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
399742011406	active site
399742011407	catalytic tetrad [active]
399742011408	hypothetical protein; Provisional; Region: PRK01254
399742011409	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
399742011410	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
399742011411	FtsI repressor; Provisional; Region: PRK10883
399742011412	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
399742011413	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
399742011414	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
399742011415	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
399742011416	putative acyl-acceptor binding pocket; other site
399742011417	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
399742011418	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
399742011419	CAP-like domain; other site
399742011420	active site
399742011421	primary dimer interface [polypeptide binding]; other site
399742011422	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
399742011423	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
399742011424	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742011425	active site
399742011426	phosphorylation site [posttranslational modification]
399742011427	intermolecular recognition site; other site
399742011428	dimerization interface [polypeptide binding]; other site
399742011429	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742011430	DNA binding site [nucleotide binding]
399742011431	sensor protein QseC; Provisional; Region: PRK10337
399742011432	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742011433	dimer interface [polypeptide binding]; other site
399742011434	phosphorylation site [posttranslational modification]
399742011435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742011436	ATP binding site [chemical binding]; other site
399742011437	Mg2+ binding site [ion binding]; other site
399742011438	G-X-G motif; other site
399742011439	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
399742011440	Uncharacterized conserved protein [Function unknown]; Region: COG1359
399742011441	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
399742011442	galactoside permease; Reviewed; Region: lacY; PRK09528
399742011443	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011444	putative substrate translocation pore; other site
399742011445	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; pfam10022
399742011446	Cupin domain; Region: Cupin_2; pfam07883
399742011447	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742011448	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
399742011449	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742011450	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
399742011451	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
399742011452	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cd04795
399742011453	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
399742011454	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
399742011455	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
399742011456	intersubunit interface [polypeptide binding]; other site
399742011457	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
399742011458	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742011459	ABC-ATPase subunit  interface; other site
399742011460	dimer interface [polypeptide binding]; other site
399742011461	putative PBP binding regions; other site
399742011462	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
399742011463	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
399742011464	dimer interface [polypeptide binding]; other site
399742011465	putative PBP binding regions; other site
399742011466	ABC-ATPase subunit  interface; other site
399742011467	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
399742011468	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
399742011469	Walker A/P-loop; other site
399742011470	ATP binding site [chemical binding]; other site
399742011471	Q-loop/lid; other site
399742011472	ABC transporter signature motif; other site
399742011473	Walker B; other site
399742011474	D-loop; other site
399742011475	H-loop/switch region; other site
399742011476	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
399742011477	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742011478	N-terminal plug; other site
399742011479	ligand-binding site [chemical binding]; other site
399742011480	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
399742011481	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742011482	ATP binding site [chemical binding]; other site
399742011483	Mg2+ binding site [ion binding]; other site
399742011484	G-X-G motif; other site
399742011485	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
399742011486	anchoring element; other site
399742011487	dimer interface [polypeptide binding]; other site
399742011488	ATP binding site [chemical binding]; other site
399742011489	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
399742011490	active site
399742011491	metal binding site [ion binding]; metal-binding site
399742011492	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
399742011493	esterase YqiA; Provisional; Region: PRK11071
399742011494	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
399742011495	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
399742011496	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
399742011497	active site
399742011498	metal binding site [ion binding]; metal-binding site
399742011499	hexamer interface [polypeptide binding]; other site
399742011500	putative dehydrogenase; Provisional; Region: PRK11039
399742011501	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
399742011502	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
399742011503	dimer interface [polypeptide binding]; other site
399742011504	ADP-ribose binding site [chemical binding]; other site
399742011505	active site
399742011506	nudix motif; other site
399742011507	metal binding site [ion binding]; metal-binding site
399742011508	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
399742011509	hypothetical protein; Provisional; Region: PRK11653
399742011510	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
399742011511	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
399742011512	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
399742011513	putative active site [active]
399742011514	metal binding site [ion binding]; metal-binding site
399742011515	zinc transporter ZupT; Provisional; Region: PRK04201
399742011516	ZIP Zinc transporter; Region: Zip; pfam02535
399742011517	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
399742011518	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
399742011519	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
399742011520	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
399742011521	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
399742011522	putative ribose interaction site [chemical binding]; other site
399742011523	putative ADP binding site [chemical binding]; other site
399742011524	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
399742011525	active site
399742011526	nucleotide binding site [chemical binding]; other site
399742011527	HIGH motif; other site
399742011528	KMSKS motif; other site
399742011529	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
399742011530	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
399742011531	metal binding triad; other site
399742011532	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
399742011533	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
399742011534	metal binding triad; other site
399742011535	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
399742011536	Uncharacterized conserved protein [Function unknown]; Region: COG3025
399742011537	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
399742011538	putative active site [active]
399742011539	putative metal binding residues [ion binding]; other site
399742011540	signature motif; other site
399742011541	putative triphosphate binding site [ion binding]; other site
399742011542	CHAD domain; Region: CHAD; pfam05235
399742011543	SH3 domain-containing protein; Provisional; Region: PRK10884
399742011544	Bacterial SH3 domain homologues; Region: SH3b; smart00287
399742011545	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
399742011546	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
399742011547	active site
399742011548	NTP binding site [chemical binding]; other site
399742011549	metal binding triad [ion binding]; metal-binding site
399742011550	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
399742011551	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
399742011552	Zn2+ binding site [ion binding]; other site
399742011553	Mg2+ binding site [ion binding]; other site
399742011554	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
399742011555	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
399742011556	homooctamer interface [polypeptide binding]; other site
399742011557	active site
399742011558	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
399742011559	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
399742011560	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
399742011561	alpha-gamma subunit interface [polypeptide binding]; other site
399742011562	beta-gamma subunit interface [polypeptide binding]; other site
399742011563	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
399742011564	gamma-beta subunit interface [polypeptide binding]; other site
399742011565	alpha-beta subunit interface [polypeptide binding]; other site
399742011566	urease subunit alpha; Reviewed; Region: ureC; PRK13207
399742011567	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
399742011568	subunit interactions [polypeptide binding]; other site
399742011569	active site
399742011570	flap region; other site
399742011571	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
399742011572	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
399742011573	dimer interface [polypeptide binding]; other site
399742011574	catalytic residues [active]
399742011575	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
399742011576	UreF; Region: UreF; pfam01730
399742011577	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
399742011578	UGMP family protein; Validated; Region: PRK09604
399742011579	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
399742011580	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
399742011581	DNA primase; Validated; Region: dnaG; PRK05667
399742011582	CHC2 zinc finger; Region: zf-CHC2; pfam01807
399742011583	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
399742011584	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
399742011585	active site
399742011586	metal binding site [ion binding]; metal-binding site
399742011587	interdomain interaction site; other site
399742011588	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
399742011589	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
399742011590	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
399742011591	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
399742011592	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
399742011593	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
399742011594	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742011595	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
399742011596	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742011597	DNA binding residues [nucleotide binding]
399742011598	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
399742011599	active site
399742011600	SUMO-1 interface [polypeptide binding]; other site
399742011601	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
399742011602	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
399742011603	tail protein; Provisional; Region: D; PHA02561
399742011604	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
399742011605	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
399742011606	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
399742011607	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
399742011608	major tail tube protein; Provisional; Region: FII; PHA02600
399742011609	major tail sheath protein; Provisional; Region: FI; PHA02560
399742011610	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
399742011611	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
399742011612	Phage Tail Collar Domain; Region: Collar; pfam07484
399742011613	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
399742011614	baseplate assembly protein; Provisional; Region: J; PHA02568
399742011615	baseplate wedge subunit; Provisional; Region: W; PHA02516
399742011616	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
399742011617	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
399742011618	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
399742011619	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
399742011620	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
399742011621	catalytic residues [active]
399742011622	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
399742011623	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
399742011624	terminase endonuclease subunit; Provisional; Region: M; PHA02537
399742011625	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
399742011626	Phage major capsid protein, P2 family; Region: Phage_cap_P2; pfam05125
399742011627	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
399742011628	terminase ATPase subunit; Provisional; Region: P; PHA02535
399742011629	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
399742011630	portal vertex protein; Provisional; Region: Q; PHA02536
399742011631	Phage portal protein; Region: Phage_portal; pfam04860
399742011632	DinI-like family; Region: DinI; cl11630
399742011633	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
399742011634	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
399742011635	Ligand Binding Site [chemical binding]; other site
399742011636	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
399742011637	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
399742011638	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
399742011639	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
399742011640	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
399742011641	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
399742011642	integrase; Provisional; Region: int; PHA02601
399742011643	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
399742011644	dimer interface [polypeptide binding]; other site
399742011645	active site
399742011646	catalytic residues [active]
399742011647	Int/Topo IB signature motif; other site
399742011648	phosphoglycerol transferase I; Provisional; Region: PRK12363
399742011649	Sulfatase; Region: Sulfatase; cl17466
399742011650	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742011651	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742011652	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_2; cd08464
399742011653	putative substrate binding pocket [chemical binding]; other site
399742011654	putative dimerization interface [polypeptide binding]; other site
399742011655	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
399742011656	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
399742011657	homotrimer interaction site [polypeptide binding]; other site
399742011658	putative active site [active]
399742011659	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
399742011660	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742011661	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
399742011662	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
399742011663	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
399742011664	HSP70 interaction site [polypeptide binding]; other site
399742011665	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
399742011666	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
399742011667	FAD binding pocket [chemical binding]; other site
399742011668	FAD binding motif [chemical binding]; other site
399742011669	phosphate binding motif [ion binding]; other site
399742011670	NAD binding pocket [chemical binding]; other site
399742011671	Predicted transcriptional regulators [Transcription]; Region: COG1695
399742011672	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
399742011673	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
399742011674	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
399742011675	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742011676	dimerization interface [polypeptide binding]; other site
399742011677	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742011678	dimer interface [polypeptide binding]; other site
399742011679	putative CheW interface [polypeptide binding]; other site
399742011680	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742011681	PAS domain; Region: PAS_9; pfam13426
399742011682	putative active site [active]
399742011683	heme pocket [chemical binding]; other site
399742011684	HAMP domain; Region: HAMP; pfam00672
399742011685	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
399742011686	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
399742011687	dimer interface [polypeptide binding]; other site
399742011688	putative CheW interface [polypeptide binding]; other site
399742011689	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
399742011690	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742011691	inhibitor-cofactor binding pocket; inhibition site
399742011692	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742011693	catalytic residue [active]
399742011694	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
399742011695	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742011696	non-specific DNA binding site [nucleotide binding]; other site
399742011697	salt bridge; other site
399742011698	sequence-specific DNA binding site [nucleotide binding]; other site
399742011699	Cupin domain; Region: Cupin_2; pfam07883
399742011700	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
399742011701	B3/4 domain; Region: B3_4; pfam03483
399742011702	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
399742011703	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
399742011704	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
399742011705	putative active site; other site
399742011706	catalytic residue [active]
399742011707	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
399742011708	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
399742011709	ligand binding site [chemical binding]; other site
399742011710	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742011711	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742011712	TM-ABC transporter signature motif; other site
399742011713	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742011714	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742011715	TM-ABC transporter signature motif; other site
399742011716	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
399742011717	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742011718	Walker A/P-loop; other site
399742011719	ATP binding site [chemical binding]; other site
399742011720	Q-loop/lid; other site
399742011721	ABC transporter signature motif; other site
399742011722	Walker B; other site
399742011723	D-loop; other site
399742011724	H-loop/switch region; other site
399742011725	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742011726	transcriptional regulator LsrR; Provisional; Region: PRK15418
399742011727	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
399742011728	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
399742011729	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
399742011730	putative N- and C-terminal domain interface [polypeptide binding]; other site
399742011731	putative active site [active]
399742011732	putative MgATP binding site [chemical binding]; other site
399742011733	catalytic site [active]
399742011734	metal binding site [ion binding]; metal-binding site
399742011735	putative carbohydrate binding site [chemical binding]; other site
399742011736	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
399742011737	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
399742011738	active site
399742011739	FMN binding site [chemical binding]; other site
399742011740	2,4-decadienoyl-CoA binding site; other site
399742011741	catalytic residue [active]
399742011742	4Fe-4S cluster binding site [ion binding]; other site
399742011743	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
399742011744	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
399742011745	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742011746	S-adenosylmethionine binding site [chemical binding]; other site
399742011747	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
399742011748	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
399742011749	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
399742011750	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
399742011751	serine/threonine transporter SstT; Provisional; Region: PRK13628
399742011752	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
399742011753	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
399742011754	galactarate dehydratase; Region: galactar-dH20; TIGR03248
399742011755	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
399742011756	Glucuronate isomerase; Region: UxaC; pfam02614
399742011757	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
399742011758	D-galactonate transporter; Region: 2A0114; TIGR00893
399742011759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011760	putative substrate translocation pore; other site
399742011761	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
399742011762	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742011763	DNA-binding site [nucleotide binding]; DNA binding site
399742011764	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
399742011765	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
399742011766	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
399742011767	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
399742011768	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
399742011769	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
399742011770	Predicted membrane protein [Function unknown]; Region: COG5393
399742011771	YqjK-like protein; Region: YqjK; pfam13997
399742011772	Predicted membrane protein [Function unknown]; Region: COG2259
399742011773	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
399742011774	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
399742011775	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
399742011776	putative dimer interface [polypeptide binding]; other site
399742011777	N-terminal domain interface [polypeptide binding]; other site
399742011778	putative substrate binding pocket (H-site) [chemical binding]; other site
399742011779	Predicted membrane protein [Function unknown]; Region: COG3152
399742011780	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742011781	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
399742011782	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742011783	dimerization interface [polypeptide binding]; other site
399742011784	Pirin-related protein [General function prediction only]; Region: COG1741
399742011785	Pirin; Region: Pirin; pfam02678
399742011786	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
399742011787	dimer interface [polypeptide binding]; other site
399742011788	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
399742011789	Pyruvate formate lyase 1; Region: PFL1; cd01678
399742011790	coenzyme A binding site [chemical binding]; other site
399742011791	active site
399742011792	catalytic residues [active]
399742011793	glycine loop; other site
399742011794	propionate/acetate kinase; Provisional; Region: PRK12379
399742011795	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
399742011796	threonine/serine transporter TdcC; Provisional; Region: PRK13629
399742011797	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
399742011798	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
399742011799	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
399742011800	tetramer interface [polypeptide binding]; other site
399742011801	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742011802	catalytic residue [active]
399742011803	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
399742011804	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742011805	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742011806	dimerization interface [polypeptide binding]; other site
399742011807	glycerate kinase I; Provisional; Region: PRK10342
399742011808	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
399742011809	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
399742011810	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
399742011811	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742011812	D-galactonate transporter; Region: 2A0114; TIGR00893
399742011813	putative substrate translocation pore; other site
399742011814	galactarate dehydratase; Region: galactar-dH20; TIGR03248
399742011815	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
399742011816	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
399742011817	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
399742011818	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
399742011819	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
399742011820	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
399742011821	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
399742011822	active site
399742011823	phosphorylation site [posttranslational modification]
399742011824	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
399742011825	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
399742011826	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
399742011827	active pocket/dimerization site; other site
399742011828	active site
399742011829	phosphorylation site [posttranslational modification]
399742011830	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
399742011831	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
399742011832	dimer interface [polypeptide binding]; other site
399742011833	active site
399742011834	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
399742011835	putative active site [active]
399742011836	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
399742011837	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
399742011838	intersubunit interface [polypeptide binding]; other site
399742011839	active site
399742011840	zinc binding site [ion binding]; other site
399742011841	Na+ binding site [ion binding]; other site
399742011842	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
399742011843	active site
399742011844	phosphorylation site [posttranslational modification]
399742011845	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
399742011846	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
399742011847	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
399742011848	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
399742011849	active site
399742011850	trimer interface [polypeptide binding]; other site
399742011851	allosteric site; other site
399742011852	active site lid [active]
399742011853	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
399742011854	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
399742011855	putative SAM binding site [chemical binding]; other site
399742011856	putative homodimer interface [polypeptide binding]; other site
399742011857	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
399742011858	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
399742011859	putative ligand binding site [chemical binding]; other site
399742011860	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
399742011861	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
399742011862	dimer interface [polypeptide binding]; other site
399742011863	active site
399742011864	outer membrane lipoprotein; Provisional; Region: PRK11023
399742011865	BON domain; Region: BON; pfam04972
399742011866	BON domain; Region: BON; pfam04972
399742011867	Predicted permease; Region: DUF318; pfam03773
399742011868	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
399742011869	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
399742011870	NAD binding site [chemical binding]; other site
399742011871	active site
399742011872	intracellular protease, PfpI family; Region: PfpI; TIGR01382
399742011873	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
399742011874	proposed catalytic triad [active]
399742011875	conserved cys residue [active]
399742011876	hypothetical protein; Provisional; Region: PRK03467
399742011877	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
399742011878	GIY-YIG motif/motif A; other site
399742011879	putative active site [active]
399742011880	putative metal binding site [ion binding]; other site
399742011881	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
399742011882	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742011883	Coenzyme A binding pocket [chemical binding]; other site
399742011884	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
399742011885	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
399742011886	Peptidase family U32; Region: Peptidase_U32; pfam01136
399742011887	putative protease; Provisional; Region: PRK15447
399742011888	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
399742011889	hypothetical protein; Provisional; Region: PRK10508
399742011890	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
399742011891	tryptophan permease; Provisional; Region: PRK10483
399742011892	aromatic amino acid transport protein; Region: araaP; TIGR00837
399742011893	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
399742011894	DEAD-like helicases superfamily; Region: DEXDc; smart00487
399742011895	ATP binding site [chemical binding]; other site
399742011896	Mg++ binding site [ion binding]; other site
399742011897	motif III; other site
399742011898	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742011899	nucleotide binding region [chemical binding]; other site
399742011900	ATP-binding site [chemical binding]; other site
399742011901	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
399742011902	putative RNA binding site [nucleotide binding]; other site
399742011903	lipoprotein NlpI; Provisional; Region: PRK11189
399742011904	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742011905	binding surface
399742011906	TPR motif; other site
399742011907	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
399742011908	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
399742011909	RNase E interface [polypeptide binding]; other site
399742011910	trimer interface [polypeptide binding]; other site
399742011911	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
399742011912	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
399742011913	RNase E interface [polypeptide binding]; other site
399742011914	trimer interface [polypeptide binding]; other site
399742011915	active site
399742011916	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
399742011917	putative nucleic acid binding region [nucleotide binding]; other site
399742011918	G-X-X-G motif; other site
399742011919	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
399742011920	RNA binding site [nucleotide binding]; other site
399742011921	domain interface; other site
399742011922	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
399742011923	16S/18S rRNA binding site [nucleotide binding]; other site
399742011924	S13e-L30e interaction site [polypeptide binding]; other site
399742011925	25S rRNA binding site [nucleotide binding]; other site
399742011926	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
399742011927	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
399742011928	RNA binding site [nucleotide binding]; other site
399742011929	active site
399742011930	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
399742011931	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
399742011932	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
399742011933	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
399742011934	translation initiation factor IF-2; Validated; Region: infB; PRK05306
399742011935	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
399742011936	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
399742011937	G1 box; other site
399742011938	putative GEF interaction site [polypeptide binding]; other site
399742011939	GTP/Mg2+ binding site [chemical binding]; other site
399742011940	Switch I region; other site
399742011941	G2 box; other site
399742011942	G3 box; other site
399742011943	Switch II region; other site
399742011944	G4 box; other site
399742011945	G5 box; other site
399742011946	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
399742011947	Translation-initiation factor 2; Region: IF-2; pfam11987
399742011948	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
399742011949	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
399742011950	NusA N-terminal domain; Region: NusA_N; pfam08529
399742011951	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
399742011952	RNA binding site [nucleotide binding]; other site
399742011953	homodimer interface [polypeptide binding]; other site
399742011954	NusA-like KH domain; Region: KH_5; pfam13184
399742011955	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
399742011956	G-X-X-G motif; other site
399742011957	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
399742011958	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
399742011959	ribosome maturation protein RimP; Reviewed; Region: PRK00092
399742011960	Sm and related proteins; Region: Sm_like; cl00259
399742011961	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
399742011962	putative oligomer interface [polypeptide binding]; other site
399742011963	putative RNA binding site [nucleotide binding]; other site
399742011964	argininosuccinate synthase; Validated; Region: PRK05370
399742011965	argininosuccinate synthase; Provisional; Region: PRK13820
399742011966	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
399742011967	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
399742011968	active site
399742011969	substrate binding site [chemical binding]; other site
399742011970	metal binding site [ion binding]; metal-binding site
399742011971	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
399742011972	dihydropteroate synthase; Region: DHPS; TIGR01496
399742011973	substrate binding pocket [chemical binding]; other site
399742011974	dimer interface [polypeptide binding]; other site
399742011975	inhibitor binding site; inhibition site
399742011976	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
399742011977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742011978	Walker A motif; other site
399742011979	ATP binding site [chemical binding]; other site
399742011980	Walker B motif; other site
399742011981	arginine finger; other site
399742011982	Peptidase family M41; Region: Peptidase_M41; pfam01434
399742011983	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
399742011984	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742011985	S-adenosylmethionine binding site [chemical binding]; other site
399742011986	RNA-binding protein YhbY; Provisional; Region: PRK10343
399742011987	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
399742011988	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
399742011989	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
399742011990	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
399742011991	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
399742011992	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
399742011993	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742011994	active site
399742011995	phosphorylation site [posttranslational modification]
399742011996	intermolecular recognition site; other site
399742011997	dimerization interface [polypeptide binding]; other site
399742011998	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742011999	DNA binding site [nucleotide binding]
399742012000	sensor protein BasS/PmrB; Provisional; Region: PRK10755
399742012001	HAMP domain; Region: HAMP; pfam00672
399742012002	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742012003	dimer interface [polypeptide binding]; other site
399742012004	phosphorylation site [posttranslational modification]
399742012005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742012006	ATP binding site [chemical binding]; other site
399742012007	Mg2+ binding site [ion binding]; other site
399742012008	G-X-G motif; other site
399742012009	GTPase CgtA; Reviewed; Region: obgE; PRK12298
399742012010	GTP1/OBG; Region: GTP1_OBG; pfam01018
399742012011	Obg GTPase; Region: Obg; cd01898
399742012012	G1 box; other site
399742012013	GTP/Mg2+ binding site [chemical binding]; other site
399742012014	Switch I region; other site
399742012015	G2 box; other site
399742012016	G3 box; other site
399742012017	Switch II region; other site
399742012018	G4 box; other site
399742012019	G5 box; other site
399742012020	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
399742012021	EamA-like transporter family; Region: EamA; pfam00892
399742012022	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
399742012023	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
399742012024	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
399742012025	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
399742012026	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
399742012027	substrate binding pocket [chemical binding]; other site
399742012028	chain length determination region; other site
399742012029	substrate-Mg2+ binding site; other site
399742012030	catalytic residues [active]
399742012031	aspartate-rich region 1; other site
399742012032	active site lid residues [active]
399742012033	aspartate-rich region 2; other site
399742012034	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
399742012035	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
399742012036	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
399742012037	hinge; other site
399742012038	active site
399742012039	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
399742012040	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
399742012041	anti sigma factor interaction site; other site
399742012042	regulatory phosphorylation site [posttranslational modification]; other site
399742012043	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
399742012044	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
399742012045	mce related protein; Region: MCE; pfam02470
399742012046	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
399742012047	conserved hypothetical integral membrane protein; Region: TIGR00056
399742012048	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
399742012049	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
399742012050	Walker A/P-loop; other site
399742012051	ATP binding site [chemical binding]; other site
399742012052	Q-loop/lid; other site
399742012053	ABC transporter signature motif; other site
399742012054	Walker B; other site
399742012055	D-loop; other site
399742012056	H-loop/switch region; other site
399742012057	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
399742012058	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
399742012059	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
399742012060	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
399742012061	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
399742012062	putative active site [active]
399742012063	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
399742012064	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
399742012065	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
399742012066	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
399742012067	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
399742012068	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
399742012069	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
399742012070	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
399742012071	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
399742012072	Walker A/P-loop; other site
399742012073	ATP binding site [chemical binding]; other site
399742012074	Q-loop/lid; other site
399742012075	ABC transporter signature motif; other site
399742012076	Walker B; other site
399742012077	D-loop; other site
399742012078	H-loop/switch region; other site
399742012079	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
399742012080	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
399742012081	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
399742012082	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
399742012083	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
399742012084	30S subunit binding site; other site
399742012085	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
399742012086	active site
399742012087	phosphorylation site [posttranslational modification]
399742012088	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
399742012089	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
399742012090	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
399742012091	dimerization domain swap beta strand [polypeptide binding]; other site
399742012092	regulatory protein interface [polypeptide binding]; other site
399742012093	active site
399742012094	regulatory phosphorylation site [posttranslational modification]; other site
399742012095	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
399742012096	Transglycosylase; Region: Transgly; cl17702
399742012097	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
399742012098	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
399742012099	conserved cys residue [active]
399742012100	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
399742012101	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
399742012102	putative active site [active]
399742012103	heme pocket [chemical binding]; other site
399742012104	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742012105	dimer interface [polypeptide binding]; other site
399742012106	phosphorylation site [posttranslational modification]
399742012107	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742012108	ATP binding site [chemical binding]; other site
399742012109	Mg2+ binding site [ion binding]; other site
399742012110	G-X-G motif; other site
399742012111	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742012112	active site
399742012113	phosphorylation site [posttranslational modification]
399742012114	intermolecular recognition site; other site
399742012115	dimerization interface [polypeptide binding]; other site
399742012116	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
399742012117	putative binding surface; other site
399742012118	active site
399742012119	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
399742012120	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
399742012121	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
399742012122	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
399742012123	multifunctional aminopeptidase A; Provisional; Region: PRK00913
399742012124	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
399742012125	interface (dimer of trimers) [polypeptide binding]; other site
399742012126	Substrate-binding/catalytic site; other site
399742012127	Zn-binding sites [ion binding]; other site
399742012128	DNA polymerase III subunit chi; Validated; Region: PRK05728
399742012129	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
399742012130	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
399742012131	HIGH motif; other site
399742012132	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
399742012133	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
399742012134	active site
399742012135	KMSKS motif; other site
399742012136	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
399742012137	tRNA binding surface [nucleotide binding]; other site
399742012138	anticodon binding site; other site
399742012139	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
399742012140	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
399742012141	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742012142	Coenzyme A binding pocket [chemical binding]; other site
399742012143	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
399742012144	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
399742012145	putative NAD(P) binding site [chemical binding]; other site
399742012146	putative substrate binding site [chemical binding]; other site
399742012147	catalytic Zn binding site [ion binding]; other site
399742012148	structural Zn binding site [ion binding]; other site
399742012149	dimer interface [polypeptide binding]; other site
399742012150	dihydroxyacetone kinase, ATP-dependent; Region: dak_ATP; TIGR02361
399742012151	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
399742012152	DAK2 domain; Region: Dak2; pfam02734
399742012153	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
399742012154	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
399742012155	Walker A motif; other site
399742012156	ATP binding site [chemical binding]; other site
399742012157	radical SAM protein, TIGR01212 family; Region: TIGR01212
399742012158	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742012159	FeS/SAM binding site; other site
399742012160	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
399742012161	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
399742012162	active site
399742012163	dimer interface [polypeptide binding]; other site
399742012164	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
399742012165	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
399742012166	active site
399742012167	FMN binding site [chemical binding]; other site
399742012168	substrate binding site [chemical binding]; other site
399742012169	3Fe-4S cluster binding site [ion binding]; other site
399742012170	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
399742012171	domain interface; other site
399742012172	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
399742012173	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
399742012174	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742012175	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
399742012176	N-acetylmannosamine kinase; Provisional; Region: PRK05082
399742012177	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
399742012178	nucleotide binding site [chemical binding]; other site
399742012179	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
399742012180	putative sialic acid transporter; Provisional; Region: PRK03893
399742012181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742012182	putative substrate translocation pore; other site
399742012183	N-acetylneuraminate lyase; Provisional; Region: PRK04147
399742012184	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
399742012185	inhibitor site; inhibition site
399742012186	active site
399742012187	dimer interface [polypeptide binding]; other site
399742012188	catalytic residue [active]
399742012189	transcriptional regulator NanR; Provisional; Region: PRK03837
399742012190	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742012191	DNA-binding site [nucleotide binding]; DNA binding site
399742012192	FCD domain; Region: FCD; pfam07729
399742012193	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
399742012194	stringent starvation protein A; Provisional; Region: sspA; PRK09481
399742012195	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
399742012196	C-terminal domain interface [polypeptide binding]; other site
399742012197	putative GSH binding site (G-site) [chemical binding]; other site
399742012198	dimer interface [polypeptide binding]; other site
399742012199	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
399742012200	dimer interface [polypeptide binding]; other site
399742012201	N-terminal domain interface [polypeptide binding]; other site
399742012202	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
399742012203	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
399742012204	23S rRNA interface [nucleotide binding]; other site
399742012205	L3 interface [polypeptide binding]; other site
399742012206	Predicted ATPase [General function prediction only]; Region: COG1485
399742012207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
399742012208	hypothetical protein; Provisional; Region: PRK11677
399742012209	serine endoprotease; Provisional; Region: PRK10139
399742012210	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
399742012211	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
399742012212	protein binding site [polypeptide binding]; other site
399742012213	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
399742012214	serine endoprotease; Provisional; Region: PRK10898
399742012215	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
399742012216	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
399742012217	malate dehydrogenase; Provisional; Region: PRK05086
399742012218	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
399742012219	NAD binding site [chemical binding]; other site
399742012220	dimerization interface [polypeptide binding]; other site
399742012221	Substrate binding site [chemical binding]; other site
399742012222	arginine repressor; Provisional; Region: PRK05066
399742012223	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
399742012224	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
399742012225	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742012226	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
399742012227	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
399742012228	RNAase interaction site [polypeptide binding]; other site
399742012229	succinic semialdehyde dehydrogenase; Region: PLN02278
399742012230	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
399742012231	tetramerization interface [polypeptide binding]; other site
399742012232	NAD(P) binding site [chemical binding]; other site
399742012233	catalytic residues [active]
399742012234	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
399742012235	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
399742012236	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
399742012237	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742012238	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742012239	efflux system membrane protein; Provisional; Region: PRK11594
399742012240	transcriptional regulator; Provisional; Region: PRK10632
399742012241	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742012242	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
399742012243	putative effector binding pocket; other site
399742012244	dimerization interface [polypeptide binding]; other site
399742012245	protease TldD; Provisional; Region: tldD; PRK10735
399742012246	hypothetical protein; Provisional; Region: PRK10899
399742012247	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
399742012248	ribonuclease G; Provisional; Region: PRK11712
399742012249	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
399742012250	homodimer interface [polypeptide binding]; other site
399742012251	oligonucleotide binding site [chemical binding]; other site
399742012252	Maf-like protein; Region: Maf; pfam02545
399742012253	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
399742012254	active site
399742012255	dimer interface [polypeptide binding]; other site
399742012256	rod shape-determining protein MreD; Provisional; Region: PRK11060
399742012257	rod shape-determining protein MreC; Region: mreC; TIGR00219
399742012258	rod shape-determining protein MreC; Region: MreC; pfam04085
399742012259	rod shape-determining protein MreB; Provisional; Region: PRK13927
399742012260	MreB and similar proteins; Region: MreB_like; cd10225
399742012261	nucleotide binding site [chemical binding]; other site
399742012262	Mg binding site [ion binding]; other site
399742012263	putative protofilament interaction site [polypeptide binding]; other site
399742012264	RodZ interaction site [polypeptide binding]; other site
399742012265	regulatory protein CsrD; Provisional; Region: PRK11059
399742012266	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742012267	metal binding site [ion binding]; metal-binding site
399742012268	active site
399742012269	I-site; other site
399742012270	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742012271	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
399742012272	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
399742012273	NADP binding site [chemical binding]; other site
399742012274	dimer interface [polypeptide binding]; other site
399742012275	TMAO/DMSO reductase; Reviewed; Region: PRK05363
399742012276	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
399742012277	Moco binding site; other site
399742012278	metal coordination site [ion binding]; other site
399742012279	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
399742012280	Dehydroquinase class II; Region: DHquinase_II; pfam01220
399742012281	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
399742012282	trimer interface [polypeptide binding]; other site
399742012283	active site
399742012284	dimer interface [polypeptide binding]; other site
399742012285	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
399742012286	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
399742012287	carboxyltransferase (CT) interaction site; other site
399742012288	biotinylation site [posttranslational modification]; other site
399742012289	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
399742012290	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
399742012291	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
399742012292	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
399742012293	hypothetical protein; Provisional; Region: PRK10633
399742012294	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
399742012295	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
399742012296	Na binding site [ion binding]; other site
399742012297	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
399742012298	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
399742012299	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
399742012300	active site
399742012301	zinc binding site [ion binding]; other site
399742012302	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
399742012303	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
399742012304	FMN binding site [chemical binding]; other site
399742012305	active site
399742012306	catalytic residues [active]
399742012307	substrate binding site [chemical binding]; other site
399742012308	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
399742012309	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
399742012310	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
399742012311	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
399742012312	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
399742012313	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
399742012314	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
399742012315	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742012316	metal binding site [ion binding]; metal-binding site
399742012317	active site
399742012318	I-site; other site
399742012319	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742012320	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
399742012321	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742012322	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
399742012323	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
399742012324	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
399742012325	HlyD family secretion protein; Region: HlyD_3; pfam13437
399742012326	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
399742012327	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742012328	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
399742012329	substrate binding pocket [chemical binding]; other site
399742012330	membrane-bound complex binding site; other site
399742012331	hinge residues; other site
399742012332	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
399742012333	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
399742012334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742012335	dimer interface [polypeptide binding]; other site
399742012336	ABC-ATPase subunit interface; other site
399742012337	putative PBP binding loops; other site
399742012338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742012339	dimer interface [polypeptide binding]; other site
399742012340	conserved gate region; other site
399742012341	putative PBP binding loops; other site
399742012342	ABC-ATPase subunit interface; other site
399742012343	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
399742012344	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
399742012345	Walker A/P-loop; other site
399742012346	ATP binding site [chemical binding]; other site
399742012347	Q-loop/lid; other site
399742012348	ABC transporter signature motif; other site
399742012349	Walker B; other site
399742012350	D-loop; other site
399742012351	H-loop/switch region; other site
399742012352	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
399742012353	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
399742012354	trimer interface [polypeptide binding]; other site
399742012355	putative metal binding site [ion binding]; other site
399742012356	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
399742012357	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
399742012358	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
399742012359	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
399742012360	shikimate binding site; other site
399742012361	NAD(P) binding site [chemical binding]; other site
399742012362	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
399742012363	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
399742012364	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
399742012365	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
399742012366	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
399742012367	hypothetical protein; Validated; Region: PRK03430
399742012368	hypothetical protein; Provisional; Region: PRK10736
399742012369	DNA protecting protein DprA; Region: dprA; TIGR00732
399742012370	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
399742012371	active site
399742012372	catalytic residues [active]
399742012373	metal binding site [ion binding]; metal-binding site
399742012374	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
399742012375	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
399742012376	putative active site [active]
399742012377	substrate binding site [chemical binding]; other site
399742012378	putative cosubstrate binding site; other site
399742012379	catalytic site [active]
399742012380	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
399742012381	substrate binding site [chemical binding]; other site
399742012382	16S rRNA methyltransferase B; Provisional; Region: PRK10901
399742012383	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
399742012384	putative RNA binding site [nucleotide binding]; other site
399742012385	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742012386	S-adenosylmethionine binding site [chemical binding]; other site
399742012387	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
399742012388	TrkA-N domain; Region: TrkA_N; pfam02254
399742012389	TrkA-C domain; Region: TrkA_C; pfam02080
399742012390	TrkA-N domain; Region: TrkA_N; pfam02254
399742012391	TrkA-C domain; Region: TrkA_C; pfam02080
399742012392	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
399742012393	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
399742012394	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
399742012395	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
399742012396	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
399742012397	DNA binding residues [nucleotide binding]
399742012398	dimer interface [polypeptide binding]; other site
399742012399	metal binding site [ion binding]; metal-binding site
399742012400	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
399742012401	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
399742012402	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
399742012403	alphaNTD homodimer interface [polypeptide binding]; other site
399742012404	alphaNTD - beta interaction site [polypeptide binding]; other site
399742012405	alphaNTD - beta' interaction site [polypeptide binding]; other site
399742012406	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
399742012407	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
399742012408	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
399742012409	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742012410	RNA binding surface [nucleotide binding]; other site
399742012411	30S ribosomal protein S11; Validated; Region: PRK05309
399742012412	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
399742012413	30S ribosomal protein S13; Region: bact_S13; TIGR03631
399742012414	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
399742012415	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
399742012416	SecY translocase; Region: SecY; pfam00344
399742012417	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
399742012418	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
399742012419	23S rRNA binding site [nucleotide binding]; other site
399742012420	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
399742012421	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
399742012422	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
399742012423	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
399742012424	23S rRNA interface [nucleotide binding]; other site
399742012425	5S rRNA interface [nucleotide binding]; other site
399742012426	L27 interface [polypeptide binding]; other site
399742012427	L5 interface [polypeptide binding]; other site
399742012428	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
399742012429	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
399742012430	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
399742012431	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
399742012432	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
399742012433	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
399742012434	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
399742012435	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
399742012436	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
399742012437	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
399742012438	RNA binding site [nucleotide binding]; other site
399742012439	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
399742012440	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
399742012441	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
399742012442	23S rRNA interface [nucleotide binding]; other site
399742012443	putative translocon interaction site; other site
399742012444	signal recognition particle (SRP54) interaction site; other site
399742012445	L23 interface [polypeptide binding]; other site
399742012446	trigger factor interaction site; other site
399742012447	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
399742012448	23S rRNA interface [nucleotide binding]; other site
399742012449	5S rRNA interface [nucleotide binding]; other site
399742012450	putative antibiotic binding site [chemical binding]; other site
399742012451	L25 interface [polypeptide binding]; other site
399742012452	L27 interface [polypeptide binding]; other site
399742012453	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
399742012454	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
399742012455	G-X-X-G motif; other site
399742012456	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
399742012457	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
399742012458	protein-rRNA interface [nucleotide binding]; other site
399742012459	putative translocon binding site; other site
399742012460	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
399742012461	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
399742012462	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
399742012463	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
399742012464	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
399742012465	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
399742012466	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
399742012467	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
399742012468	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
399742012469	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
399742012470	heme binding site [chemical binding]; other site
399742012471	ferroxidase pore; other site
399742012472	ferroxidase diiron center [ion binding]; other site
399742012473	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
399742012474	elongation factor Tu; Reviewed; Region: PRK00049
399742012475	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
399742012476	G1 box; other site
399742012477	GEF interaction site [polypeptide binding]; other site
399742012478	GTP/Mg2+ binding site [chemical binding]; other site
399742012479	Switch I region; other site
399742012480	G2 box; other site
399742012481	G3 box; other site
399742012482	Switch II region; other site
399742012483	G4 box; other site
399742012484	G5 box; other site
399742012485	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
399742012486	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
399742012487	Antibiotic Binding Site [chemical binding]; other site
399742012488	elongation factor G; Reviewed; Region: PRK00007
399742012489	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
399742012490	G1 box; other site
399742012491	putative GEF interaction site [polypeptide binding]; other site
399742012492	GTP/Mg2+ binding site [chemical binding]; other site
399742012493	Switch I region; other site
399742012494	G2 box; other site
399742012495	G3 box; other site
399742012496	Switch II region; other site
399742012497	G4 box; other site
399742012498	G5 box; other site
399742012499	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
399742012500	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
399742012501	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
399742012502	30S ribosomal protein S7; Validated; Region: PRK05302
399742012503	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
399742012504	S17 interaction site [polypeptide binding]; other site
399742012505	S8 interaction site; other site
399742012506	16S rRNA interaction site [nucleotide binding]; other site
399742012507	streptomycin interaction site [chemical binding]; other site
399742012508	23S rRNA interaction site [nucleotide binding]; other site
399742012509	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
399742012510	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
399742012511	sulfur relay protein TusC; Validated; Region: PRK00211
399742012512	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
399742012513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
399742012514	YheO-like PAS domain; Region: PAS_6; pfam08348
399742012515	HTH domain; Region: HTH_22; pfam13309
399742012516	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
399742012517	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
399742012518	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
399742012519	phi X174 lysis protein; Provisional; Region: PRK02793
399742012520	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
399742012521	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
399742012522	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
399742012523	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
399742012524	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
399742012525	TrkA-N domain; Region: TrkA_N; pfam02254
399742012526	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
399742012527	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
399742012528	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742012529	Walker A/P-loop; other site
399742012530	ATP binding site [chemical binding]; other site
399742012531	Q-loop/lid; other site
399742012532	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742012533	ABC transporter; Region: ABC_tran_2; pfam12848
399742012534	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
399742012535	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742012536	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742012537	The C-terminal substrate-binding domian of LysR-type transcriptional regulator MdcR, which involved in the malonate catabolism contains the type 2 periplasmic binding fold; Region: PBP2_MdcR; cd08416
399742012538	putative dimerization interface [polypeptide binding]; other site
399742012539	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
399742012540	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
399742012541	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293
399742012542	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
399742012543	Membrane transport protein; Region: Mem_trans; cl09117
399742012544	Malonate decarboxylase gamma subunit (MdcE); Region: MdcE; pfam06833
399742012545	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189
399742012546	Malonate decarboxylase delta subunit (MdcD); Region: ACP; cl06082
399742012547	triphosphoribosyl-dephospho-CoA synthase; Validated; Region: PRK01237
399742012548	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
399742012549	Coenzyme A transferase; Region: CoA_trans; cl17247
399742012550	putative hydrolase; Provisional; Region: PRK10985
399742012551	hypothetical protein; Provisional; Region: PRK04966
399742012552	phosphoribulokinase; Provisional; Region: PRK15453
399742012553	active site
399742012554	hypothetical protein; Provisional; Region: PRK10738
399742012555	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
399742012556	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
399742012557	ligand binding site [chemical binding]; other site
399742012558	flexible hinge region; other site
399742012559	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
399742012560	putative switch regulator; other site
399742012561	non-specific DNA interactions [nucleotide binding]; other site
399742012562	DNA binding site [nucleotide binding]
399742012563	sequence specific DNA binding site [nucleotide binding]; other site
399742012564	putative cAMP binding site [chemical binding]; other site
399742012565	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
399742012566	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
399742012567	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
399742012568	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
399742012569	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742012570	inhibitor-cofactor binding pocket; inhibition site
399742012571	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742012572	catalytic residue [active]
399742012573	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
399742012574	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
399742012575	glutamine binding [chemical binding]; other site
399742012576	catalytic triad [active]
399742012577	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
399742012578	cell filamentation protein Fic; Provisional; Region: PRK10347
399742012579	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
399742012580	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
399742012581	substrate binding site [chemical binding]; other site
399742012582	putative transporter; Provisional; Region: PRK03699
399742012583	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742012584	putative substrate translocation pore; other site
399742012585	cytosine deaminase; Provisional; Region: PRK09230
399742012586	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
399742012587	active site
399742012588	nitrite reductase subunit NirD; Provisional; Region: PRK14989
399742012589	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742012590	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
399742012591	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
399742012592	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
399742012593	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
399742012594	nitrite transporter NirC; Provisional; Region: PRK11562
399742012595	siroheme synthase; Provisional; Region: cysG; PRK10637
399742012596	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
399742012597	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
399742012598	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
399742012599	active site
399742012600	SAM binding site [chemical binding]; other site
399742012601	homodimer interface [polypeptide binding]; other site
399742012602	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
399742012603	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
399742012604	active site
399742012605	HIGH motif; other site
399742012606	dimer interface [polypeptide binding]; other site
399742012607	KMSKS motif; other site
399742012608	phosphoglycolate phosphatase; Provisional; Region: PRK13222
399742012609	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742012610	motif II; other site
399742012611	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
399742012612	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
399742012613	substrate binding site [chemical binding]; other site
399742012614	hexamer interface [polypeptide binding]; other site
399742012615	metal binding site [ion binding]; metal-binding site
399742012616	DNA adenine methylase; Provisional; Region: PRK10904
399742012617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
399742012618	cell division protein DamX; Validated; Region: PRK10905
399742012619	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
399742012620	active site
399742012621	dimer interface [polypeptide binding]; other site
399742012622	metal binding site [ion binding]; metal-binding site
399742012623	shikimate kinase; Reviewed; Region: aroK; PRK00131
399742012624	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
399742012625	ADP binding site [chemical binding]; other site
399742012626	magnesium binding site [ion binding]; other site
399742012627	putative shikimate binding site; other site
399742012628	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
399742012629	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
399742012630	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
399742012631	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
399742012632	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
399742012633	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
399742012634	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
399742012635	Transglycosylase; Region: Transgly; pfam00912
399742012636	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
399742012637	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
399742012638	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
399742012639	ADP-ribose binding site [chemical binding]; other site
399742012640	dimer interface [polypeptide binding]; other site
399742012641	active site
399742012642	nudix motif; other site
399742012643	metal binding site [ion binding]; metal-binding site
399742012644	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
399742012645	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
399742012646	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742012647	motif II; other site
399742012648	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
399742012649	RNA binding surface [nucleotide binding]; other site
399742012650	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
399742012651	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
399742012652	dimerization interface [polypeptide binding]; other site
399742012653	domain crossover interface; other site
399742012654	redox-dependent activation switch; other site
399742012655	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
399742012656	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
399742012657	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
399742012658	active site
399742012659	substrate-binding site [chemical binding]; other site
399742012660	metal-binding site [ion binding]
399742012661	ATP binding site [chemical binding]; other site
399742012662	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
399742012663	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742012664	dimerization interface [polypeptide binding]; other site
399742012665	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742012666	dimer interface [polypeptide binding]; other site
399742012667	phosphorylation site [posttranslational modification]
399742012668	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742012669	ATP binding site [chemical binding]; other site
399742012670	G-X-G motif; other site
399742012671	osmolarity response regulator; Provisional; Region: ompR; PRK09468
399742012672	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742012673	active site
399742012674	phosphorylation site [posttranslational modification]
399742012675	intermolecular recognition site; other site
399742012676	dimerization interface [polypeptide binding]; other site
399742012677	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742012678	DNA binding site [nucleotide binding]
399742012679	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
399742012680	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
399742012681	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
399742012682	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
399742012683	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
399742012684	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
399742012685	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
399742012686	RNA binding site [nucleotide binding]; other site
399742012687	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
399742012688	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
399742012689	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
399742012690	G1 box; other site
399742012691	GTP/Mg2+ binding site [chemical binding]; other site
399742012692	Switch I region; other site
399742012693	G2 box; other site
399742012694	G3 box; other site
399742012695	Switch II region; other site
399742012696	G4 box; other site
399742012697	G5 box; other site
399742012698	Nucleoside recognition; Region: Gate; pfam07670
399742012699	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
399742012700	Nucleoside recognition; Region: Gate; pfam07670
399742012701	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
399742012702	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
399742012703	carboxylesterase BioH; Provisional; Region: PRK10349
399742012704	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
399742012705	DNA utilization protein GntX; Provisional; Region: PRK11595
399742012706	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
399742012707	active site
399742012708	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
399742012709	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
399742012710	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
399742012711	high-affinity gluconate transporter; Provisional; Region: PRK14984
399742012712	gluconate transporter; Region: gntP; TIGR00791
399742012713	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
399742012714	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
399742012715	maltodextrin phosphorylase; Provisional; Region: PRK14985
399742012716	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
399742012717	active site pocket [active]
399742012718	transcriptional regulator MalT; Provisional; Region: PRK04841
399742012719	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
399742012720	DNA binding residues [nucleotide binding]
399742012721	dimerization interface [polypeptide binding]; other site
399742012722	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
399742012723	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
399742012724	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
399742012725	intramembrane serine protease GlpG; Provisional; Region: PRK10907
399742012726	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
399742012727	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
399742012728	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
399742012729	active site residue [active]
399742012730	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
399742012731	glycogen phosphorylase; Provisional; Region: PRK14986
399742012732	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
399742012733	homodimer interface [polypeptide binding]; other site
399742012734	active site pocket [active]
399742012735	glycogen synthase; Provisional; Region: glgA; PRK00654
399742012736	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
399742012737	ADP-binding pocket [chemical binding]; other site
399742012738	homodimer interface [polypeptide binding]; other site
399742012739	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
399742012740	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
399742012741	ligand binding site; other site
399742012742	oligomer interface; other site
399742012743	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
399742012744	dimer interface [polypeptide binding]; other site
399742012745	N-terminal domain interface [polypeptide binding]; other site
399742012746	sulfate 1 binding site; other site
399742012747	glycogen debranching enzyme; Provisional; Region: PRK03705
399742012748	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
399742012749	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
399742012750	active site
399742012751	catalytic site [active]
399742012752	glycogen branching enzyme; Provisional; Region: PRK05402
399742012753	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
399742012754	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
399742012755	active site
399742012756	catalytic site [active]
399742012757	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
399742012758	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
399742012759	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
399742012760	putative antibiotic transporter; Provisional; Region: PRK10739
399742012761	low affinity gluconate transporter; Provisional; Region: PRK10472
399742012762	gluconate transporter; Region: gntP; TIGR00791
399742012763	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
399742012764	ATP-binding site [chemical binding]; other site
399742012765	Gluconate-6-phosphate binding site [chemical binding]; other site
399742012766	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
399742012767	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742012768	DNA binding site [nucleotide binding]
399742012769	domain linker motif; other site
399742012770	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
399742012771	putative ligand binding site [chemical binding]; other site
399742012772	putative dimerization interface [polypeptide binding]; other site
399742012773	Pirin-related protein [General function prediction only]; Region: COG1741
399742012774	Pirin; Region: Pirin; pfam02678
399742012775	putative oxidoreductase; Provisional; Region: PRK10206
399742012776	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
399742012777	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
399742012778	putative acetyltransferase YhhY; Provisional; Region: PRK10140
399742012779	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742012780	Coenzyme A binding pocket [chemical binding]; other site
399742012781	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
399742012782	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
399742012783	hypothetical protein; Provisional; Region: PRK10350
399742012784	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
399742012785	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
399742012786	putative active site [active]
399742012787	catalytic site [active]
399742012788	putative metal binding site [ion binding]; other site
399742012789	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
399742012790	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
399742012791	Walker A/P-loop; other site
399742012792	ATP binding site [chemical binding]; other site
399742012793	Q-loop/lid; other site
399742012794	ABC transporter signature motif; other site
399742012795	Walker B; other site
399742012796	D-loop; other site
399742012797	H-loop/switch region; other site
399742012798	TOBE domain; Region: TOBE_2; pfam08402
399742012799	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
399742012800	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742012801	dimer interface [polypeptide binding]; other site
399742012802	conserved gate region; other site
399742012803	ABC-ATPase subunit interface; other site
399742012804	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
399742012805	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742012806	putative PBP binding loops; other site
399742012807	ABC-ATPase subunit interface; other site
399742012808	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
399742012809	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
399742012810	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
399742012811	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
399742012812	Walker A/P-loop; other site
399742012813	ATP binding site [chemical binding]; other site
399742012814	Q-loop/lid; other site
399742012815	ABC transporter signature motif; other site
399742012816	Walker B; other site
399742012817	D-loop; other site
399742012818	H-loop/switch region; other site
399742012819	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
399742012820	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
399742012821	Walker A/P-loop; other site
399742012822	ATP binding site [chemical binding]; other site
399742012823	Q-loop/lid; other site
399742012824	ABC transporter signature motif; other site
399742012825	Walker B; other site
399742012826	D-loop; other site
399742012827	H-loop/switch region; other site
399742012828	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
399742012829	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
399742012830	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
399742012831	TM-ABC transporter signature motif; other site
399742012832	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742012833	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
399742012834	TM-ABC transporter signature motif; other site
399742012835	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
399742012836	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
399742012837	dimerization interface [polypeptide binding]; other site
399742012838	ligand binding site [chemical binding]; other site
399742012839	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
399742012840	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
399742012841	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
399742012842	dimerization interface [polypeptide binding]; other site
399742012843	ligand binding site [chemical binding]; other site
399742012844	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
399742012845	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
399742012846	inhibitor-cofactor binding pocket; inhibition site
399742012847	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742012848	catalytic residue [active]
399742012849	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
399742012850	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
399742012851	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
399742012852	DNA binding residues [nucleotide binding]
399742012853	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
399742012854	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
399742012855	cell division protein FtsE; Provisional; Region: PRK10908
399742012856	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
399742012857	Walker A/P-loop; other site
399742012858	ATP binding site [chemical binding]; other site
399742012859	Q-loop/lid; other site
399742012860	ABC transporter signature motif; other site
399742012861	Walker B; other site
399742012862	D-loop; other site
399742012863	H-loop/switch region; other site
399742012864	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
399742012865	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
399742012866	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
399742012867	P loop; other site
399742012868	GTP binding site [chemical binding]; other site
399742012869	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
399742012870	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742012871	S-adenosylmethionine binding site [chemical binding]; other site
399742012872	hypothetical protein; Provisional; Region: PRK10910
399742012873	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
399742012874	Predicted membrane protein [Function unknown]; Region: COG3714
399742012875	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
399742012876	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
399742012877	metal-binding site [ion binding]
399742012878	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
399742012879	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742012880	motif II; other site
399742012881	DctM-like transporters; Region: DctM; pfam06808
399742012882	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
399742012883	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
399742012884	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
399742012885	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
399742012886	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
399742012887	CPxP  motif; other site
399742012888	hypothetical protein; Provisional; Region: PRK11212
399742012889	hypothetical protein; Provisional; Region: PRK11615
399742012890	major facilitator superfamily transporter; Provisional; Region: PRK05122
399742012891	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742012892	putative substrate translocation pore; other site
399742012893	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
399742012894	Domain of unknown function DUF20; Region: UPF0118; pfam01594
399742012895	Methyltransferase domain; Region: Methyltransf_18; pfam12847
399742012896	S-adenosylmethionine binding site [chemical binding]; other site
399742012897	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
399742012898	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
399742012899	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
399742012900	putative acyl-acceptor binding pocket; other site
399742012901	Phosphopantetheine attachment site; Region: PP-binding; cl09936
399742012902	acyl carrier protein; Provisional; Region: PRK05350
399742012903	Predicted membrane protein [Function unknown]; Region: COG4648
399742012904	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
399742012905	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
399742012906	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
399742012907	AMP binding site [chemical binding]; other site
399742012908	active site
399742012909	acyl-activating enzyme (AAE) consensus motif; other site
399742012910	acyl-activating enzyme (AAE) consensus motif; other site
399742012911	CoA binding site [chemical binding]; other site
399742012912	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
399742012913	active site 2 [active]
399742012914	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
399742012915	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
399742012916	Ligand binding site; other site
399742012917	Putative Catalytic site; other site
399742012918	DXD motif; other site
399742012919	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
399742012920	putative acyl-acceptor binding pocket; other site
399742012921	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
399742012922	active site
399742012923	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
399742012924	Predicted exporter [General function prediction only]; Region: COG4258
399742012925	Protein of unknown function (DUF3261); Region: DUF3261; pfam11659
399742012926	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
399742012927	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
399742012928	dimer interface [polypeptide binding]; other site
399742012929	active site
399742012930	Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289
399742012931	putative active site 1 [active]
399742012932	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742012933	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
399742012934	NAD(P) binding site [chemical binding]; other site
399742012935	active site
399742012936	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
399742012937	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
399742012938	dimer interface [polypeptide binding]; other site
399742012939	active site
399742012940	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
399742012941	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
399742012942	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
399742012943	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742012944	NAD(P) binding site [chemical binding]; other site
399742012945	active site
399742012946	NlpC/P60 family; Region: NLPC_P60; pfam00877
399742012947	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
399742012948	Integral membrane protein TerC family; Region: TerC; cl10468
399742012949	Ion channel; Region: Ion_trans_2; pfam07885
399742012950	Predicted flavoproteins [General function prediction only]; Region: COG2081
399742012951	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
399742012952	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
399742012953	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
399742012954	universal stress protein UspB; Provisional; Region: PRK04960
399742012955	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
399742012956	Ligand Binding Site [chemical binding]; other site
399742012957	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742012958	S-adenosylmethionine binding site [chemical binding]; other site
399742012959	oligopeptidase A; Provisional; Region: PRK10911
399742012960	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
399742012961	active site
399742012962	Zn binding site [ion binding]; other site
399742012963	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
399742012964	glutathione reductase; Validated; Region: PRK06116
399742012965	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
399742012966	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742012967	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
399742012968	trehalase; Provisional; Region: treF; PRK13270
399742012969	Trehalase; Region: Trehalase; pfam01204
399742012970	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
399742012971	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742012972	Coenzyme A binding pocket [chemical binding]; other site
399742012973	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
399742012974	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
399742012975	NAD(P) binding site [chemical binding]; other site
399742012976	active site
399742012977	Transcriptional regulator [Transcription]; Region: LysR; COG0583
399742012978	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742012979	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
399742012980	putative effector binding pocket; other site
399742012981	putative dimerization interface [polypeptide binding]; other site
399742012982	inner membrane protein YhjD; Region: TIGR00766
399742012983	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742012984	metabolite-proton symporter; Region: 2A0106; TIGR00883
399742012985	putative substrate translocation pore; other site
399742012986	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
399742012987	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
399742012988	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742012989	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
399742012990	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
399742012991	substrate binding site [chemical binding]; other site
399742012992	ATP binding site [chemical binding]; other site
399742012993	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
399742012994	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
399742012995	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
399742012996	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
399742012997	putative diguanylate cyclase; Provisional; Region: PRK13561
399742012998	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
399742012999	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
399742013000	metal binding site [ion binding]; metal-binding site
399742013001	active site
399742013002	I-site; other site
399742013003	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
399742013004	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
399742013005	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742013006	binding surface
399742013007	TPR motif; other site
399742013008	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742013009	binding surface
399742013010	TPR motif; other site
399742013011	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
399742013012	endo-1,4-D-glucanase; Provisional; Region: PRK11097
399742013013	cellulose synthase regulator protein; Provisional; Region: PRK11114
399742013014	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
399742013015	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
399742013016	DXD motif; other site
399742013017	Cellulose synthase-like protein; Region: PLN02893
399742013018	PilZ domain; Region: PilZ; pfam07238
399742013019	cell division protein; Provisional; Region: PRK10037
399742013020	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
399742013021	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
399742013022	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
399742013023	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
399742013024	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
399742013025	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
399742013026	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
399742013027	Cellulose synthase subunit D; Region: Cellsynth_D; pfam03500
399742013028	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
399742013029	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
399742013030	binding surface
399742013031	TPR motif; other site
399742013032	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
399742013033	binding surface
399742013034	TPR motif; other site
399742013035	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
399742013036	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
399742013037	cellulose synthase regulator protein; Provisional; Region: PRK11114
399742013038	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
399742013039	Cellulose synthase-like protein; Region: PLN02893
399742013040	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
399742013041	DXD motif; other site
399742013042	PilZ domain; Region: PilZ; pfam07238
399742013043	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
399742013044	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
399742013045	P-loop; other site
399742013046	Magnesium ion binding site [ion binding]; other site
399742013047	Biotin operon repressor [Transcription]; Region: BirA; COG1654
399742013048	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
399742013049	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
399742013050	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
399742013051	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
399742013052	FAD binding domain; Region: FAD_binding_4; pfam01565
399742013053	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
399742013054	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
399742013055	potassium transporter; Provisional; Region: PRK10750
399742013056	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
399742013057	hypothetical protein; Provisional; Region: PRK11568
399742013058	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
399742013059	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
399742013060	proline dipeptidase; Provisional; Region: PRK13607
399742013061	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
399742013062	active site
399742013063	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
399742013064	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
399742013065	substrate binding site [chemical binding]; other site
399742013066	oxyanion hole (OAH) forming residues; other site
399742013067	trimer interface [polypeptide binding]; other site
399742013068	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
399742013069	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
399742013070	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
399742013071	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
399742013072	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
399742013073	dimer interface [polypeptide binding]; other site
399742013074	active site
399742013075	FMN reductase; Validated; Region: fre; PRK08051
399742013076	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
399742013077	FAD binding pocket [chemical binding]; other site
399742013078	FAD binding motif [chemical binding]; other site
399742013079	phosphate binding motif [ion binding]; other site
399742013080	beta-alpha-beta structure motif; other site
399742013081	NAD binding pocket [chemical binding]; other site
399742013082	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
399742013083	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
399742013084	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
399742013085	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
399742013086	active site
399742013087	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
399742013088	sec-independent translocase; Provisional; Region: PRK01770
399742013089	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
399742013090	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
399742013091	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
399742013092	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
399742013093	SCP-2 sterol transfer family; Region: SCP2; pfam02036
399742013094	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
399742013095	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742013096	S-adenosylmethionine binding site [chemical binding]; other site
399742013097	DNA recombination protein RmuC; Provisional; Region: PRK10361
399742013098	RmuC family; Region: RmuC; pfam02646
399742013099	uridine phosphorylase; Provisional; Region: PRK11178
399742013100	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
399742013101	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
399742013102	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
399742013103	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
399742013104	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
399742013105	active site turn [active]
399742013106	phosphorylation site [posttranslational modification]
399742013107	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
399742013108	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
399742013109	HPr interaction site; other site
399742013110	glycerol kinase (GK) interaction site [polypeptide binding]; other site
399742013111	active site
399742013112	phosphorylation site [posttranslational modification]
399742013113	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
399742013114	beta-galactosidase; Region: BGL; TIGR03356
399742013115	transcriptional antiterminator BglG; Provisional; Region: PRK09772
399742013116	CAT RNA binding domain; Region: CAT_RBD; smart01061
399742013117	PRD domain; Region: PRD; pfam00874
399742013118	PRD domain; Region: PRD; pfam00874
399742013119	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
399742013120	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
399742013121	THF binding site; other site
399742013122	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
399742013123	substrate binding site [chemical binding]; other site
399742013124	THF binding site; other site
399742013125	zinc-binding site [ion binding]; other site
399742013126	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
399742013127	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742013128	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
399742013129	putative dimerization interface [polypeptide binding]; other site
399742013130	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
399742013131	EamA-like transporter family; Region: EamA; pfam00892
399742013132	putative hydrolase; Provisional; Region: PRK10976
399742013133	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742013134	active site
399742013135	motif I; other site
399742013136	motif II; other site
399742013137	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742013138	lysophospholipase L2; Provisional; Region: PRK10749
399742013139	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
399742013140	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
399742013141	threonine efflux system; Provisional; Region: PRK10229
399742013142	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
399742013143	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742013144	ATP binding site [chemical binding]; other site
399742013145	putative Mg++ binding site [ion binding]; other site
399742013146	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742013147	nucleotide binding region [chemical binding]; other site
399742013148	ATP-binding site [chemical binding]; other site
399742013149	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
399742013150	HRDC domain; Region: HRDC; pfam00570
399742013151	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
399742013152	dimerization interface [polypeptide binding]; other site
399742013153	substrate binding site [chemical binding]; other site
399742013154	active site
399742013155	calcium binding site [ion binding]; other site
399742013156	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
399742013157	CoenzymeA binding site [chemical binding]; other site
399742013158	subunit interaction site [polypeptide binding]; other site
399742013159	PHB binding site; other site
399742013160	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
399742013161	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
399742013162	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
399742013163	Cl binding site [ion binding]; other site
399742013164	oligomer interface [polypeptide binding]; other site
399742013165	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
399742013166	Part of AAA domain; Region: AAA_19; pfam13245
399742013167	Family description; Region: UvrD_C_2; pfam13538
399742013168	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
399742013169	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742013170	motif II; other site
399742013171	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
399742013172	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
399742013173	active site
399742013174	DNA binding site [nucleotide binding]
399742013175	Int/Topo IB signature motif; other site
399742013176	hypothetical protein; Provisional; Region: PRK10963
399742013177	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
399742013178	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
399742013179	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
399742013180	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
399742013181	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
399742013182	putative iron binding site [ion binding]; other site
399742013183	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
399742013184	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
399742013185	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
399742013186	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
399742013187	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
399742013188	domain interfaces; other site
399742013189	active site
399742013190	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
399742013191	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
399742013192	active site
399742013193	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
399742013194	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
399742013195	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
399742013196	HemY protein N-terminus; Region: HemY_N; pfam07219
399742013197	Tetratricopeptide repeat; Region: TPR_2; pfam07719
399742013198	putative transport protein YifK; Provisional; Region: PRK10746
399742013199	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
399742013200	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
399742013201	putative common antigen polymerase; Provisional; Region: PRK02975
399742013202	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
399742013203	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
399742013204	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
399742013205	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
399742013206	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
399742013207	inhibitor-cofactor binding pocket; inhibition site
399742013208	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742013209	catalytic residue [active]
399742013210	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
399742013211	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
399742013212	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
399742013213	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
399742013214	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
399742013215	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
399742013216	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
399742013217	active site
399742013218	homodimer interface [polypeptide binding]; other site
399742013219	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
399742013220	Chain length determinant protein; Region: Wzz; cl15801
399742013221	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
399742013222	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
399742013223	Mg++ binding site [ion binding]; other site
399742013224	putative catalytic motif [active]
399742013225	substrate binding site [chemical binding]; other site
399742013226	transcription termination factor Rho; Provisional; Region: rho; PRK09376
399742013227	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
399742013228	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
399742013229	RNA binding site [nucleotide binding]; other site
399742013230	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
399742013231	multimer interface [polypeptide binding]; other site
399742013232	Walker A motif; other site
399742013233	ATP binding site [chemical binding]; other site
399742013234	Walker B motif; other site
399742013235	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
399742013236	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
399742013237	catalytic residues [active]
399742013238	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
399742013239	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
399742013240	ATP binding site [chemical binding]; other site
399742013241	Mg++ binding site [ion binding]; other site
399742013242	motif III; other site
399742013243	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
399742013244	nucleotide binding region [chemical binding]; other site
399742013245	ATP-binding site [chemical binding]; other site
399742013246	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
399742013247	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
399742013248	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
399742013249	Part of AAA domain; Region: AAA_19; pfam13245
399742013250	Family description; Region: UvrD_C_2; pfam13538
399742013251	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
399742013252	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
399742013253	ketol-acid reductoisomerase; Validated; Region: PRK05225
399742013254	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
399742013255	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
399742013256	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
399742013257	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742013258	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
399742013259	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
399742013260	putative dimerization interface [polypeptide binding]; other site
399742013261	threonine dehydratase; Reviewed; Region: PRK09224
399742013262	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
399742013263	tetramer interface [polypeptide binding]; other site
399742013264	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742013265	catalytic residue [active]
399742013266	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
399742013267	putative Ile/Val binding site [chemical binding]; other site
399742013268	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
399742013269	putative Ile/Val binding site [chemical binding]; other site
399742013270	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
399742013271	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
399742013272	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
399742013273	homodimer interface [polypeptide binding]; other site
399742013274	substrate-cofactor binding pocket; other site
399742013275	catalytic residue [active]
399742013276	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
399742013277	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
399742013278	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
399742013279	PYR/PP interface [polypeptide binding]; other site
399742013280	dimer interface [polypeptide binding]; other site
399742013281	TPP binding site [chemical binding]; other site
399742013282	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
399742013283	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
399742013284	TPP-binding site [chemical binding]; other site
399742013285	dimer interface [polypeptide binding]; other site
399742013286	putative ATP-dependent protease; Provisional; Region: PRK09862
399742013287	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
399742013288	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742013289	Walker A motif; other site
399742013290	ATP binding site [chemical binding]; other site
399742013291	Walker B motif; other site
399742013292	arginine finger; other site
399742013293	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
399742013294	hypothetical protein; Provisional; Region: PRK11027
399742013295	transcriptional regulator HdfR; Provisional; Region: PRK03601
399742013296	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742013297	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
399742013298	dimerization interface [polypeptide binding]; other site
399742013299	glutamate racemase; Provisional; Region: PRK00865
399742013300	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
399742013301	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
399742013302	N-terminal plug; other site
399742013303	ligand-binding site [chemical binding]; other site
399742013304	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
399742013305	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742013306	S-adenosylmethionine binding site [chemical binding]; other site
399742013307	hypothetical protein; Provisional; Region: PRK11056
399742013308	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
399742013309	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
399742013310	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
399742013311	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
399742013312	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
399742013313	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
399742013314	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742013315	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
399742013316	dimerization interface [polypeptide binding]; other site
399742013317	argininosuccinate lyase; Provisional; Region: PRK04833
399742013318	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
399742013319	active sites [active]
399742013320	tetramer interface [polypeptide binding]; other site
399742013321	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
399742013322	nucleotide binding site [chemical binding]; other site
399742013323	N-acetyl-L-glutamate binding site [chemical binding]; other site
399742013324	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
399742013325	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
399742013326	acetylornithine deacetylase; Provisional; Region: PRK05111
399742013327	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
399742013328	metal binding site [ion binding]; metal-binding site
399742013329	putative dimer interface [polypeptide binding]; other site
399742013330	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
399742013331	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
399742013332	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
399742013333	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
399742013334	dimer interface [polypeptide binding]; other site
399742013335	active site
399742013336	metal binding site [ion binding]; metal-binding site
399742013337	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
399742013338	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
399742013339	heme binding site [chemical binding]; other site
399742013340	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
399742013341	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
399742013342	FAD binding site [chemical binding]; other site
399742013343	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
399742013344	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
399742013345	putative catalytic residues [active]
399742013346	putative nucleotide binding site [chemical binding]; other site
399742013347	putative aspartate binding site [chemical binding]; other site
399742013348	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
399742013349	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
399742013350	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
399742013351	cystathionine gamma-synthase; Provisional; Region: PRK08045
399742013352	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
399742013353	homodimer interface [polypeptide binding]; other site
399742013354	substrate-cofactor binding pocket; other site
399742013355	pyridoxal 5'-phosphate binding site [chemical binding]; other site
399742013356	catalytic residue [active]
399742013357	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
399742013358	dimerization interface [polypeptide binding]; other site
399742013359	DNA binding site [nucleotide binding]
399742013360	corepressor binding sites; other site
399742013361	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
399742013362	primosome assembly protein PriA; Validated; Region: PRK05580
399742013363	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
399742013364	ATP binding site [chemical binding]; other site
399742013365	putative Mg++ binding site [ion binding]; other site
399742013366	helicase superfamily c-terminal domain; Region: HELICc; smart00490
399742013367	ATP-binding site [chemical binding]; other site
399742013368	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742013369	DNA binding site [nucleotide binding]
399742013370	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
399742013371	domain linker motif; other site
399742013372	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
399742013373	dimerization interface [polypeptide binding]; other site
399742013374	ligand binding site [chemical binding]; other site
399742013375	essential cell division protein FtsN; Provisional; Region: PRK10927
399742013376	cell division protein FtsN; Provisional; Region: PRK12757
399742013377	Sporulation related domain; Region: SPOR; cl10051
399742013378	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
399742013379	active site
399742013380	HslU subunit interaction site [polypeptide binding]; other site
399742013381	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
399742013382	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742013383	Walker A motif; other site
399742013384	ATP binding site [chemical binding]; other site
399742013385	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
399742013386	Walker B motif; other site
399742013387	arginine finger; other site
399742013388	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
399742013389	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
399742013390	UbiA prenyltransferase family; Region: UbiA; pfam01040
399742013391	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
399742013392	septal ring assembly protein ZapB; Provisional; Region: PRK15422
399742013393	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
399742013394	amphipathic channel; other site
399742013395	Asn-Pro-Ala signature motifs; other site
399742013396	glycerol kinase; Provisional; Region: glpK; PRK00047
399742013397	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
399742013398	N- and C-terminal domain interface [polypeptide binding]; other site
399742013399	active site
399742013400	MgATP binding site [chemical binding]; other site
399742013401	catalytic site [active]
399742013402	metal binding site [ion binding]; metal-binding site
399742013403	glycerol binding site [chemical binding]; other site
399742013404	homotetramer interface [polypeptide binding]; other site
399742013405	homodimer interface [polypeptide binding]; other site
399742013406	FBP binding site [chemical binding]; other site
399742013407	protein IIAGlc interface [polypeptide binding]; other site
399742013408	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
399742013409	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
399742013410	putative active site [active]
399742013411	ferredoxin-NADP reductase; Provisional; Region: PRK10926
399742013412	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
399742013413	FAD binding pocket [chemical binding]; other site
399742013414	FAD binding motif [chemical binding]; other site
399742013415	phosphate binding motif [ion binding]; other site
399742013416	beta-alpha-beta structure motif; other site
399742013417	NAD binding pocket [chemical binding]; other site
399742013418	Predicted membrane protein [Function unknown]; Region: COG3152
399742013419	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
399742013420	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
399742013421	triosephosphate isomerase; Provisional; Region: PRK14567
399742013422	substrate binding site [chemical binding]; other site
399742013423	dimer interface [polypeptide binding]; other site
399742013424	catalytic triad [active]
399742013425	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
399742013426	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
399742013427	CDP-diacylglycerol pyrophosphatase; Provisional; Region: PRK05471
399742013428	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742013429	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
399742013430	substrate binding pocket [chemical binding]; other site
399742013431	membrane-bound complex binding site; other site
399742013432	hinge residues; other site
399742013433	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
399742013434	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
399742013435	active site
399742013436	ADP/pyrophosphate binding site [chemical binding]; other site
399742013437	dimerization interface [polypeptide binding]; other site
399742013438	allosteric effector site; other site
399742013439	fructose-1,6-bisphosphate binding site; other site
399742013440	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
399742013441	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
399742013442	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
399742013443	Beta-lactamase; Region: Beta-lactamase; pfam00144
399742013444	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
399742013445	dimer interface [polypeptide binding]; other site
399742013446	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
399742013447	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742013448	active site
399742013449	intermolecular recognition site; other site
399742013450	dimerization interface [polypeptide binding]; other site
399742013451	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
399742013452	DNA binding site [nucleotide binding]
399742013453	two-component sensor protein; Provisional; Region: cpxA; PRK09470
399742013454	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
399742013455	dimerization interface [polypeptide binding]; other site
399742013456	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742013457	dimer interface [polypeptide binding]; other site
399742013458	phosphorylation site [posttranslational modification]
399742013459	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742013460	ATP binding site [chemical binding]; other site
399742013461	Mg2+ binding site [ion binding]; other site
399742013462	G-X-G motif; other site
399742013463	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
399742013464	MOSC domain; Region: MOSC; pfam03473
399742013465	3-alpha domain; Region: 3-alpha; pfam03475
399742013466	superoxide dismutase; Provisional; Region: PRK10925
399742013467	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
399742013468	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
399742013469	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
399742013470	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
399742013471	transcriptional activator RhaR; Provisional; Region: PRK13502
399742013472	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742013473	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742013474	transcriptional activator RhaS; Provisional; Region: PRK13503
399742013475	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
399742013476	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742013477	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
399742013478	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
399742013479	N- and C-terminal domain interface [polypeptide binding]; other site
399742013480	active site
399742013481	putative catalytic site [active]
399742013482	metal binding site [ion binding]; metal-binding site
399742013483	ATP binding site [chemical binding]; other site
399742013484	rhamnulokinase; Provisional; Region: rhaB; PRK10640
399742013485	carbohydrate binding site [chemical binding]; other site
399742013486	L-rhamnose isomerase; Provisional; Region: PRK01076
399742013487	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
399742013488	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
399742013489	intersubunit interface [polypeptide binding]; other site
399742013490	active site
399742013491	Zn2+ binding site [ion binding]; other site
399742013492	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
399742013493	rhamnose ABC transporter, rhamnose-binding protein; Region: RhaS; TIGR02637
399742013494	ligand binding site [chemical binding]; other site
399742013495	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
399742013496	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742013497	Walker A/P-loop; other site
399742013498	ATP binding site [chemical binding]; other site
399742013499	Q-loop/lid; other site
399742013500	ABC transporter signature motif; other site
399742013501	Walker B; other site
399742013502	D-loop; other site
399742013503	H-loop/switch region; other site
399742013504	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742013505	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742013506	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742013507	TM-ABC transporter signature motif; other site
399742013508	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742013509	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742013510	TM-ABC transporter signature motif; other site
399742013511	lactaldehyde reductase; Region: lactal_redase; TIGR02638
399742013512	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
399742013513	dimer interface [polypeptide binding]; other site
399742013514	active site
399742013515	metal binding site [ion binding]; metal-binding site
399742013516	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
399742013517	galactoside permease; Reviewed; Region: lacY; PRK09528
399742013518	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742013519	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
399742013520	Melibiase; Region: Melibiase; pfam02065
399742013521	Transcriptional regulators [Transcription]; Region: PurR; COG1609
399742013522	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742013523	DNA binding site [nucleotide binding]
399742013524	domain linker motif; other site
399742013525	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
399742013526	ligand binding site [chemical binding]; other site
399742013527	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
399742013528	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
399742013529	non-specific DNA binding site [nucleotide binding]; other site
399742013530	salt bridge; other site
399742013531	sequence-specific DNA binding site [nucleotide binding]; other site
399742013532	Cupin domain; Region: Cupin_2; cl17218
399742013533	AzlC protein; Region: AzlC; cl00570
399742013534	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
399742013535	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
399742013536	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742013537	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
399742013538	molybdopterin cofactor binding site; other site
399742013539	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
399742013540	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
399742013541	molybdopterin cofactor binding site; other site
399742013542	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
399742013543	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
399742013544	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
399742013545	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
399742013546	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
399742013547	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
399742013548	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
399742013549	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
399742013550	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
399742013551	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
399742013552	Coenzyme A binding pocket [chemical binding]; other site
399742013553	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
399742013554	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
399742013555	putative active site [active]
399742013556	dimerization interface [polypeptide binding]; other site
399742013557	putative tRNAtyr binding site [nucleotide binding]; other site
399742013558	hypothetical protein; Reviewed; Region: PRK01637
399742013559	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
399742013560	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742013561	motif II; other site
399742013562	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
399742013563	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
399742013564	G1 box; other site
399742013565	putative GEF interaction site [polypeptide binding]; other site
399742013566	GTP/Mg2+ binding site [chemical binding]; other site
399742013567	Switch I region; other site
399742013568	G2 box; other site
399742013569	G3 box; other site
399742013570	Switch II region; other site
399742013571	G4 box; other site
399742013572	G5 box; other site
399742013573	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
399742013574	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
399742013575	glutamine synthetase; Provisional; Region: glnA; PRK09469
399742013576	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
399742013577	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
399742013578	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
399742013579	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
399742013580	putative active site [active]
399742013581	heme pocket [chemical binding]; other site
399742013582	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
399742013583	dimer interface [polypeptide binding]; other site
399742013584	phosphorylation site [posttranslational modification]
399742013585	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
399742013586	ATP binding site [chemical binding]; other site
399742013587	Mg2+ binding site [ion binding]; other site
399742013588	G-X-G motif; other site
399742013589	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
399742013590	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
399742013591	active site
399742013592	phosphorylation site [posttranslational modification]
399742013593	intermolecular recognition site; other site
399742013594	dimerization interface [polypeptide binding]; other site
399742013595	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742013596	Walker A motif; other site
399742013597	ATP binding site [chemical binding]; other site
399742013598	Walker B motif; other site
399742013599	arginine finger; other site
399742013600	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
399742013601	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
399742013602	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
399742013603	FeS/SAM binding site; other site
399742013604	HemN C-terminal domain; Region: HemN_C; pfam06969
399742013605	Der GTPase activator; Provisional; Region: PRK05244
399742013606	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
399742013607	G1 box; other site
399742013608	GTP/Mg2+ binding site [chemical binding]; other site
399742013609	Switch I region; other site
399742013610	G2 box; other site
399742013611	G3 box; other site
399742013612	Switch II region; other site
399742013613	G4 box; other site
399742013614	G5 box; other site
399742013615	DNA polymerase I; Provisional; Region: PRK05755
399742013616	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
399742013617	active site
399742013618	metal binding site 1 [ion binding]; metal-binding site
399742013619	putative 5' ssDNA interaction site; other site
399742013620	metal binding site 3; metal-binding site
399742013621	metal binding site 2 [ion binding]; metal-binding site
399742013622	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
399742013623	putative DNA binding site [nucleotide binding]; other site
399742013624	putative metal binding site [ion binding]; other site
399742013625	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
399742013626	active site
399742013627	catalytic site [active]
399742013628	substrate binding site [chemical binding]; other site
399742013629	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
399742013630	active site
399742013631	DNA binding site [nucleotide binding]
399742013632	catalytic site [active]
399742013633	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
399742013634	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
399742013635	catalytic residues [active]
399742013636	hinge region; other site
399742013637	alpha helical domain; other site
399742013638	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
399742013639	serine/threonine protein kinase; Provisional; Region: PRK11768
399742013640	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
399742013641	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
399742013642	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
399742013643	GTP binding site; other site
399742013644	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
399742013645	Walker A motif; other site
399742013646	Transcriptional regulators [Transcription]; Region: FadR; COG2186
399742013647	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
399742013648	DNA-binding site [nucleotide binding]; DNA binding site
399742013649	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
399742013650	putative transporter; Provisional; Region: PRK10504
399742013651	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742013652	putative substrate translocation pore; other site
399742013653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742013654	transcriptional repressor RbsR; Provisional; Region: PRK10423
399742013655	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
399742013656	DNA binding site [nucleotide binding]
399742013657	domain linker motif; other site
399742013658	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
399742013659	dimerization interface [polypeptide binding]; other site
399742013660	ligand binding site [chemical binding]; other site
399742013661	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
399742013662	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
399742013663	substrate binding site [chemical binding]; other site
399742013664	dimer interface [polypeptide binding]; other site
399742013665	ATP binding site [chemical binding]; other site
399742013666	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
399742013667	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
399742013668	ligand binding site [chemical binding]; other site
399742013669	dimerization interface [polypeptide binding]; other site
399742013670	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
399742013671	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
399742013672	TM-ABC transporter signature motif; other site
399742013673	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
399742013674	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
399742013675	Walker A/P-loop; other site
399742013676	ATP binding site [chemical binding]; other site
399742013677	Q-loop/lid; other site
399742013678	ABC transporter signature motif; other site
399742013679	Walker B; other site
399742013680	D-loop; other site
399742013681	H-loop/switch region; other site
399742013682	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
399742013683	D-ribose pyranase; Provisional; Region: PRK11797
399742013684	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
399742013685	potassium uptake protein; Region: kup; TIGR00794
399742013686	regulatory ATPase RavA; Provisional; Region: PRK13531
399742013687	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
399742013688	Walker A motif; other site
399742013689	ATP binding site [chemical binding]; other site
399742013690	Walker B motif; other site
399742013691	arginine finger; other site
399742013692	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
399742013693	hypothetical protein; Provisional; Region: yieM; PRK10997
399742013694	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
399742013695	metal ion-dependent adhesion site (MIDAS); other site
399742013696	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
399742013697	dimer interface [polypeptide binding]; other site
399742013698	active site
399742013699	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
399742013700	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
399742013701	putative DNA binding site [nucleotide binding]; other site
399742013702	putative Zn2+ binding site [ion binding]; other site
399742013703	AsnC family; Region: AsnC_trans_reg; pfam01037
399742013704	FMN-binding protein MioC; Provisional; Region: PRK09004
399742013705	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
399742013706	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
399742013707	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
399742013708	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
399742013709	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
399742013710	S-adenosylmethionine binding site [chemical binding]; other site
399742013711	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
399742013712	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
399742013713	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
399742013714	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
399742013715	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
399742013716	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
399742013717	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
399742013718	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
399742013719	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
399742013720	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
399742013721	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
399742013722	beta subunit interaction interface [polypeptide binding]; other site
399742013723	Walker A motif; other site
399742013724	ATP binding site [chemical binding]; other site
399742013725	Walker B motif; other site
399742013726	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
399742013727	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
399742013728	core domain interface [polypeptide binding]; other site
399742013729	delta subunit interface [polypeptide binding]; other site
399742013730	epsilon subunit interface [polypeptide binding]; other site
399742013731	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
399742013732	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
399742013733	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
399742013734	alpha subunit interaction interface [polypeptide binding]; other site
399742013735	Walker A motif; other site
399742013736	ATP binding site [chemical binding]; other site
399742013737	Walker B motif; other site
399742013738	inhibitor binding site; inhibition site
399742013739	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
399742013740	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
399742013741	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
399742013742	gamma subunit interface [polypeptide binding]; other site
399742013743	epsilon subunit interface [polypeptide binding]; other site
399742013744	LBP interface [polypeptide binding]; other site
399742013745	Right handed beta helix region; Region: Beta_helix; pfam13229
399742013746	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
399742013747	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
399742013748	Substrate binding site; other site
399742013749	Mg++ binding site; other site
399742013750	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
399742013751	active site
399742013752	substrate binding site [chemical binding]; other site
399742013753	CoA binding site [chemical binding]; other site
399742013754	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
399742013755	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
399742013756	glutaminase active site [active]
399742013757	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
399742013758	dimer interface [polypeptide binding]; other site
399742013759	active site
399742013760	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
399742013761	dimer interface [polypeptide binding]; other site
399742013762	active site
399742013763	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
399742013764	substrate binding pocket [chemical binding]; other site
399742013765	membrane-bound complex binding site; other site
399742013766	hinge residues; other site
399742013767	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
399742013768	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742013769	dimer interface [polypeptide binding]; other site
399742013770	conserved gate region; other site
399742013771	putative PBP binding loops; other site
399742013772	ABC-ATPase subunit interface; other site
399742013773	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
399742013774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
399742013775	dimer interface [polypeptide binding]; other site
399742013776	conserved gate region; other site
399742013777	putative PBP binding loops; other site
399742013778	ABC-ATPase subunit interface; other site
399742013779	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
399742013780	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
399742013781	Walker A/P-loop; other site
399742013782	ATP binding site [chemical binding]; other site
399742013783	Q-loop/lid; other site
399742013784	ABC transporter signature motif; other site
399742013785	Walker B; other site
399742013786	D-loop; other site
399742013787	H-loop/switch region; other site
399742013788	transcriptional regulator PhoU; Provisional; Region: PRK11115
399742013789	PhoU domain; Region: PhoU; pfam01895
399742013790	PhoU domain; Region: PhoU; pfam01895
399742013791	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
399742013792	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
399742013793	motif I; other site
399742013794	active site
399742013795	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
399742013796	Predicted flavoprotein [General function prediction only]; Region: COG0431
399742013797	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
399742013798	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
399742013799	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
399742013800	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
399742013801	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
399742013802	substrate binding pocket [chemical binding]; other site
399742013803	dimerization interface [polypeptide binding]; other site
399742013804	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
399742013805	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
399742013806	putative substrate translocation pore; other site
399742013807	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
399742013808	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
399742013809	trmE is a tRNA modification GTPase; Region: trmE; cd04164
399742013810	G1 box; other site
399742013811	GTP/Mg2+ binding site [chemical binding]; other site
399742013812	Switch I region; other site
399742013813	G2 box; other site
399742013814	Switch II region; other site
399742013815	G3 box; other site
399742013816	G4 box; other site
399742013817	G5 box; other site
399742013818	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
399742013819	membrane protein insertase; Provisional; Region: PRK01318
399742013820	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
399742013821	hypothetical protein; Validated; Region: PRK00041
399742013822	ribonuclease P; Reviewed; Region: rnpA; PRK01732
399742013823	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399