-- dump date   	20140619_073603
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
701347000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
701347000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
701347000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347000004	Walker A motif; other site
701347000005	ATP binding site [chemical binding]; other site
701347000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
701347000007	Walker B motif; other site
701347000008	arginine finger; other site
701347000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
701347000010	DnaA box-binding interface [nucleotide binding]; other site
701347000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
701347000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
701347000013	putative DNA binding surface [nucleotide binding]; other site
701347000014	dimer interface [polypeptide binding]; other site
701347000015	beta-clamp/clamp loader binding surface; other site
701347000016	beta-clamp/translesion DNA polymerase binding surface; other site
701347000017	recF protein; Region: recf; TIGR00611
701347000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347000019	Walker A/P-loop; other site
701347000020	ATP binding site [chemical binding]; other site
701347000021	Q-loop/lid; other site
701347000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347000023	ABC transporter signature motif; other site
701347000024	Walker B; other site
701347000025	D-loop; other site
701347000026	H-loop/switch region; other site
701347000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
701347000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347000029	Mg2+ binding site [ion binding]; other site
701347000030	G-X-G motif; other site
701347000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
701347000032	anchoring element; other site
701347000033	dimer interface [polypeptide binding]; other site
701347000034	ATP binding site [chemical binding]; other site
701347000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
701347000036	active site
701347000037	putative metal-binding site [ion binding]; other site
701347000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
701347000039	sugar phosphate phosphatase; Provisional; Region: PRK10513
701347000040	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347000041	active site
701347000042	motif I; other site
701347000043	motif II; other site
701347000044	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347000045	Transcriptional regulators [Transcription]; Region: FadR; COG2186
701347000046	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347000047	DNA-binding site [nucleotide binding]; DNA binding site
701347000048	FCD domain; Region: FCD; pfam07729
701347000049	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
701347000050	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
701347000051	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
701347000052	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
701347000053	active site
701347000054	intersubunit interface [polypeptide binding]; other site
701347000055	catalytic residue [active]
701347000056	galactonate dehydratase; Provisional; Region: PRK14017
701347000057	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
701347000058	putative active site pocket [active]
701347000059	putative metal binding site [ion binding]; other site
701347000060	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000061	D-galactonate transporter; Region: 2A0114; TIGR00893
701347000062	putative substrate translocation pore; other site
701347000063	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
701347000064	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
701347000065	hypothetical protein; Provisional; Region: PRK11616
701347000066	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
701347000067	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
701347000068	putative dimer interface [polypeptide binding]; other site
701347000069	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
701347000070	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
701347000071	putative dimer interface [polypeptide binding]; other site
701347000072	putative transporter; Validated; Region: PRK03818
701347000073	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
701347000074	TrkA-C domain; Region: TrkA_C; pfam02080
701347000075	TrkA-C domain; Region: TrkA_C; pfam02080
701347000076	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
701347000077	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
701347000078	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347000079	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347000080	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347000081	putative transporter; Provisional; Region: PRK10484
701347000082	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
701347000083	Na binding site [ion binding]; other site
701347000084	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
701347000085	Sulfatase; Region: Sulfatase; pfam00884
701347000086	Predicted membrane protein [Function unknown]; Region: COG2149
701347000087	Domain of unknown function (DUF202); Region: DUF202; pfam02656
701347000088	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
701347000089	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347000090	FeS/SAM binding site; other site
701347000091	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
701347000092	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
701347000093	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
701347000094	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347000095	catalytic residue [active]
701347000096	permease DsdX; Provisional; Region: PRK09921
701347000097	gluconate transporter; Region: gntP; TIGR00791
701347000098	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
701347000099	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347000100	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
701347000101	dimerization interface [polypeptide binding]; other site
701347000102	substrate binding pocket [chemical binding]; other site
701347000103	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
701347000104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000105	putative substrate translocation pore; other site
701347000106	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
701347000107	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347000108	non-specific DNA binding site [nucleotide binding]; other site
701347000109	salt bridge; other site
701347000110	sequence-specific DNA binding site [nucleotide binding]; other site
701347000111	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
701347000112	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
701347000113	PYR/PP interface [polypeptide binding]; other site
701347000114	dimer interface [polypeptide binding]; other site
701347000115	TPP binding site [chemical binding]; other site
701347000116	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347000117	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
701347000118	TPP-binding site [chemical binding]; other site
701347000119	dimer interface [polypeptide binding]; other site
701347000120	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
701347000121	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
701347000122	putative valine binding site [chemical binding]; other site
701347000123	dimer interface [polypeptide binding]; other site
701347000124	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
701347000125	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
701347000126	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347000127	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347000128	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
701347000129	substrate binding site [chemical binding]; other site
701347000130	dimer interface [polypeptide binding]; other site
701347000131	ATP binding site [chemical binding]; other site
701347000132	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
701347000133	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000134	putative substrate translocation pore; other site
701347000135	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
701347000136	active site
701347000137	catalytic residues [active]
701347000138	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
701347000139	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347000140	active site
701347000141	phosphorylation site [posttranslational modification]
701347000142	intermolecular recognition site; other site
701347000143	dimerization interface [polypeptide binding]; other site
701347000144	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347000145	DNA binding residues [nucleotide binding]
701347000146	dimerization interface [polypeptide binding]; other site
701347000147	sensory histidine kinase UhpB; Provisional; Region: PRK11644
701347000148	MASE1; Region: MASE1; pfam05231
701347000149	Histidine kinase; Region: HisKA_3; pfam07730
701347000150	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347000151	ATP binding site [chemical binding]; other site
701347000152	Mg2+ binding site [ion binding]; other site
701347000153	G-X-G motif; other site
701347000154	regulatory protein UhpC; Provisional; Region: PRK11663
701347000155	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000156	putative substrate translocation pore; other site
701347000157	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
701347000158	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000159	putative substrate translocation pore; other site
701347000160	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
701347000161	Predicted transcriptional regulator [Transcription]; Region: COG2944
701347000162	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347000163	non-specific DNA binding site [nucleotide binding]; other site
701347000164	salt bridge; other site
701347000165	sequence-specific DNA binding site [nucleotide binding]; other site
701347000166	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
701347000167	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000168	putative substrate translocation pore; other site
701347000169	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
701347000170	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347000171	motif II; other site
701347000172	2-aminoethylphosphonate--pyruvate transaminase; Provisional; Region: PRK13479
701347000173	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347000174	catalytic residue [active]
701347000175	transcriptional regulator protein; Region: phnR; TIGR03337
701347000176	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347000177	DNA-binding site [nucleotide binding]; DNA binding site
701347000178	UTRA domain; Region: UTRA; pfam07702
701347000179	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
701347000180	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
701347000181	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
701347000182	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347000183	Walker A/P-loop; other site
701347000184	ATP binding site [chemical binding]; other site
701347000185	Q-loop/lid; other site
701347000186	ABC transporter signature motif; other site
701347000187	Walker B; other site
701347000188	D-loop; other site
701347000189	H-loop/switch region; other site
701347000190	TOBE domain; Region: TOBE_2; pfam08402
701347000191	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
701347000192	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347000193	dimer interface [polypeptide binding]; other site
701347000194	conserved gate region; other site
701347000195	putative PBP binding loops; other site
701347000196	ABC-ATPase subunit interface; other site
701347000197	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
701347000198	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347000199	dimer interface [polypeptide binding]; other site
701347000200	conserved gate region; other site
701347000201	ABC-ATPase subunit interface; other site
701347000202	EamA-like transporter family; Region: EamA; pfam00892
701347000203	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
701347000204	EamA-like transporter family; Region: EamA; pfam00892
701347000205	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
701347000206	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347000207	active site turn [active]
701347000208	phosphorylation site [posttranslational modification]
701347000209	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347000210	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
701347000211	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
701347000212	putative active site [active]
701347000213	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347000214	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
701347000215	Coenzyme A binding pocket [chemical binding]; other site
701347000216	pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613
701347000217	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347000218	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
701347000219	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000220	putative substrate translocation pore; other site
701347000221	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
701347000222	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
701347000223	Cupin; Region: Cupin_6; pfam12852
701347000224	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347000225	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347000226	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
701347000227	lipoprotein, YaeC family; Region: TIGR00363
701347000228	sensor protein QseC; Provisional; Region: PRK10337
701347000229	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347000230	dimer interface [polypeptide binding]; other site
701347000231	phosphorylation site [posttranslational modification]
701347000232	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347000233	ATP binding site [chemical binding]; other site
701347000234	Mg2+ binding site [ion binding]; other site
701347000235	G-X-G motif; other site
701347000236	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
701347000237	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347000238	active site
701347000239	phosphorylation site [posttranslational modification]
701347000240	intermolecular recognition site; other site
701347000241	dimerization interface [polypeptide binding]; other site
701347000242	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347000243	DNA binding site [nucleotide binding]
701347000244	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4705
701347000245	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
701347000246	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
701347000247	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
701347000248	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
701347000249	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
701347000250	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
701347000251	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
701347000252	Predicted membrane protein [Function unknown]; Region: COG2259
701347000253	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; cl01262
701347000254	hypothetical protein; Provisional; Region: PRK05409
701347000255	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
701347000256	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
701347000257	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347000258	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347000259	dimerization interface [polypeptide binding]; other site
701347000260	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
701347000261	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
701347000262	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
701347000263	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
701347000264	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
701347000265	CoA binding domain; Region: CoA_binding; pfam02629
701347000266	CoA-ligase; Region: Ligase_CoA; pfam00549
701347000267	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
701347000268	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
701347000269	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
701347000270	putative substrate binding site [chemical binding]; other site
701347000271	nucleotide binding site [chemical binding]; other site
701347000272	nucleotide binding site [chemical binding]; other site
701347000273	homodimer interface [polypeptide binding]; other site
701347000274	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
701347000275	nucleoside/Zn binding site; other site
701347000276	dimer interface [polypeptide binding]; other site
701347000277	catalytic motif [active]
701347000278	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
701347000279	Na binding site [ion binding]; other site
701347000280	putative transporter; Provisional; Region: PRK11462
701347000281	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
701347000282	putative alpha-glucosidase; Provisional; Region: PRK10658
701347000283	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
701347000284	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
701347000285	active site
701347000286	homotrimer interface [polypeptide binding]; other site
701347000287	catalytic site [active]
701347000288	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
701347000289	AsmA family; Region: AsmA; pfam05170
701347000290	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
701347000291	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
701347000292	glycerol kinase; Provisional; Region: glpK; PRK00047
701347000293	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
701347000294	N- and C-terminal domain interface [polypeptide binding]; other site
701347000295	active site
701347000296	MgATP binding site [chemical binding]; other site
701347000297	catalytic site [active]
701347000298	metal binding site [ion binding]; metal-binding site
701347000299	glycerol binding site [chemical binding]; other site
701347000300	homotetramer interface [polypeptide binding]; other site
701347000301	homodimer interface [polypeptide binding]; other site
701347000302	FBP binding site [chemical binding]; other site
701347000303	protein IIAGlc interface [polypeptide binding]; other site
701347000304	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
701347000305	amphipathic channel; other site
701347000306	Asn-Pro-Ala signature motifs; other site
701347000307	septal ring assembly protein ZapB; Provisional; Region: PRK15422
701347000308	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
701347000309	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347000310	membrane-bound complex binding site; other site
701347000311	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
701347000312	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
701347000313	transmembrane helices; other site
701347000314	CDP-diacylglycerol pyrophosphatase; Provisional; Region: PRK05471
701347000315	transmembrane helices; other site
701347000316	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
701347000317	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
701347000318	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
701347000319	triosephosphate isomerase; Provisional; Region: PRK14567
701347000320	substrate binding site [chemical binding]; other site
701347000321	dimer interface [polypeptide binding]; other site
701347000322	catalytic triad [active]
701347000323	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
701347000324	Predicted membrane protein [Function unknown]; Region: COG3152
701347000325	ferredoxin-NADP reductase; Provisional; Region: PRK10926
701347000326	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
701347000327	FAD binding pocket [chemical binding]; other site
701347000328	FAD binding motif [chemical binding]; other site
701347000329	phosphate binding motif [ion binding]; other site
701347000330	beta-alpha-beta structure motif; other site
701347000331	NAD binding pocket [chemical binding]; other site
701347000332	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
701347000333	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
701347000334	putative active site [active]
701347000335	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
701347000336	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
701347000337	generic binding surface II; other site
701347000338	ssDNA binding site; other site
701347000339	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347000340	ATP binding site [chemical binding]; other site
701347000341	putative Mg++ binding site [ion binding]; other site
701347000342	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347000343	nucleotide binding region [chemical binding]; other site
701347000344	ATP-binding site [chemical binding]; other site
701347000345	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
701347000346	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
701347000347	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
701347000348	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
701347000349	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
701347000350	Zn2+ binding site [ion binding]; other site
701347000351	Mg2+ binding site [ion binding]; other site
701347000352	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
701347000353	synthetase active site [active]
701347000354	NTP binding site [chemical binding]; other site
701347000355	metal binding site [ion binding]; metal-binding site
701347000356	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
701347000357	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
701347000358	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
701347000359	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
701347000360	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
701347000361	catalytic site [active]
701347000362	G-X2-G-X-G-K; other site
701347000363	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
701347000364	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
701347000365	nucleotide binding pocket [chemical binding]; other site
701347000366	K-X-D-G motif; other site
701347000367	catalytic site [active]
701347000368	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
701347000369	Predicted membrane protein [Function unknown]; Region: COG2860
701347000370	UPF0126 domain; Region: UPF0126; pfam03458
701347000371	UPF0126 domain; Region: UPF0126; pfam03458
701347000372	hypothetical protein; Provisional; Region: PRK11820
701347000373	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
701347000374	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
701347000375	ribonuclease PH; Reviewed; Region: rph; PRK00173
701347000376	Ribonuclease PH; Region: RNase_PH_bact; cd11362
701347000377	hexamer interface [polypeptide binding]; other site
701347000378	active site
701347000379	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347000380	active site
701347000381	division inhibitor protein; Provisional; Region: slmA; PRK09480
701347000382	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347000383	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
701347000384	trimer interface [polypeptide binding]; other site
701347000385	active site
701347000386	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
701347000387	Flavoprotein; Region: Flavoprotein; pfam02441
701347000388	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
701347000389	hypothetical protein; Reviewed; Region: PRK00024
701347000390	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
701347000391	MPN+ (JAMM) motif; other site
701347000392	Zinc-binding site [ion binding]; other site
701347000393	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
701347000394	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
701347000395	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
701347000396	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
701347000397	DNA binding site [nucleotide binding]
701347000398	catalytic residue [active]
701347000399	H2TH interface [polypeptide binding]; other site
701347000400	putative catalytic residues [active]
701347000401	turnover-facilitating residue; other site
701347000402	intercalation triad [nucleotide binding]; other site
701347000403	8OG recognition residue [nucleotide binding]; other site
701347000404	putative reading head residues; other site
701347000405	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
701347000406	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
701347000407	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
701347000408	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
701347000409	active site
701347000410	(T/H)XGH motif; other site
701347000411	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
701347000412	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
701347000413	putative metal binding site; other site
701347000414	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
701347000415	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
701347000416	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
701347000417	putative glycosyl transferase; Provisional; Region: PRK10073
701347000418	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
701347000419	active site
701347000420	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
701347000421	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
701347000422	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
701347000423	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
701347000424	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
701347000425	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
701347000426	putative active site [active]
701347000427	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
701347000428	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
701347000429	putative active site [active]
701347000430	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
701347000431	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
701347000432	putative active site [active]
701347000433	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
701347000434	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
701347000435	NADP binding site [chemical binding]; other site
701347000436	homopentamer interface [polypeptide binding]; other site
701347000437	substrate binding site [chemical binding]; other site
701347000438	active site
701347000439	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
701347000440	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
701347000441	substrate-cofactor binding pocket; other site
701347000442	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347000443	catalytic residue [active]
701347000444	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
701347000445	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
701347000446	NAD(P) binding site [chemical binding]; other site
701347000447	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
701347000448	O-Antigen ligase; Region: Wzy_C; pfam04932
701347000449	putative glycosyl transferase; Provisional; Region: PRK10018
701347000450	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
701347000451	active site
701347000452	Capsular polysaccharide synthesis protein; Region: Caps_synth; pfam05704
701347000453	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
701347000454	NodB motif; other site
701347000455	putative active site [active]
701347000456	putative catalytic site [active]
701347000457	Zn binding site [ion binding]; other site
701347000458	AmiB activator; Provisional; Region: PRK11637
701347000459	Peptidase family M23; Region: Peptidase_M23; pfam01551
701347000460	phosphoglyceromutase; Provisional; Region: PRK05434
701347000461	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
701347000462	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
701347000463	active site residue [active]
701347000464	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
701347000465	GSH binding site [chemical binding]; other site
701347000466	catalytic residues [active]
701347000467	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
701347000468	SecA binding site; other site
701347000469	Preprotein binding site; other site
701347000470	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
701347000471	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
701347000472	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
701347000473	serine acetyltransferase; Provisional; Region: cysE; PRK11132
701347000474	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
701347000475	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
701347000476	trimer interface [polypeptide binding]; other site
701347000477	active site
701347000478	substrate binding site [chemical binding]; other site
701347000479	CoA binding site [chemical binding]; other site
701347000480	putative rRNA methylase; Provisional; Region: PRK10358
701347000481	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
701347000482	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
701347000483	active site
701347000484	substrate binding site [chemical binding]; other site
701347000485	FMN binding site [chemical binding]; other site
701347000486	putative catalytic residues [active]
701347000487	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
701347000488	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347000489	DNA-binding site [nucleotide binding]; DNA binding site
701347000490	FCD domain; Region: FCD; pfam07729
701347000491	L-lactate permease; Provisional; Region: PRK10420
701347000492	glycolate transporter; Provisional; Region: PRK09695
701347000493	hypothetical protein; Provisional; Region: PRK11020
701347000494	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
701347000495	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
701347000496	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
701347000497	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
701347000498	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
701347000499	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
701347000500	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
701347000501	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
701347000502	active site
701347000503	P-loop; other site
701347000504	phosphorylation site [posttranslational modification]
701347000505	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347000506	active site
701347000507	phosphorylation site [posttranslational modification]
701347000508	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
701347000509	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
701347000510	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347000511	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347000512	putative glutathione S-transferase; Provisional; Region: PRK10357
701347000513	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
701347000514	putative C-terminal domain interface [polypeptide binding]; other site
701347000515	putative GSH binding site (G-site) [chemical binding]; other site
701347000516	putative dimer interface [polypeptide binding]; other site
701347000517	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
701347000518	dimer interface [polypeptide binding]; other site
701347000519	N-terminal domain interface [polypeptide binding]; other site
701347000520	putative substrate binding pocket (H-site) [chemical binding]; other site
701347000521	selenocysteine synthase; Provisional; Region: PRK04311
701347000522	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
701347000523	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
701347000524	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347000525	catalytic residue [active]
701347000526	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
701347000527	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
701347000528	G1 box; other site
701347000529	putative GEF interaction site [polypeptide binding]; other site
701347000530	GTP/Mg2+ binding site [chemical binding]; other site
701347000531	Switch I region; other site
701347000532	G2 box; other site
701347000533	G3 box; other site
701347000534	Switch II region; other site
701347000535	G4 box; other site
701347000536	G5 box; other site
701347000537	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
701347000538	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
701347000539	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
701347000540	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
701347000541	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347000542	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347000543	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347000544	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
701347000545	DNA binding site [nucleotide binding]
701347000546	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
701347000547	DNA binding site [nucleotide binding]
701347000548	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347000549	dimerization interface [polypeptide binding]; other site
701347000550	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347000551	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347000552	dimer interface [polypeptide binding]; other site
701347000553	putative CheW interface [polypeptide binding]; other site
701347000554	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
701347000555	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
701347000556	intersubunit interface [polypeptide binding]; other site
701347000557	active site
701347000558	Zn2+ binding site [ion binding]; other site
701347000559	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
701347000560	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
701347000561	AP (apurinic/apyrimidinic) site pocket; other site
701347000562	DNA interaction; other site
701347000563	Metal-binding active site; metal-binding site
701347000564	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
701347000565	active site
701347000566	dimer interface [polypeptide binding]; other site
701347000567	magnesium binding site [ion binding]; other site
701347000568	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
701347000569	putative N- and C-terminal domain interface [polypeptide binding]; other site
701347000570	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
701347000571	putative active site [active]
701347000572	MgATP binding site [chemical binding]; other site
701347000573	catalytic site [active]
701347000574	metal binding site [ion binding]; metal-binding site
701347000575	putative xylulose binding site [chemical binding]; other site
701347000576	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
701347000577	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000578	D-galactonate transporter; Region: 2A0114; TIGR00893
701347000579	putative substrate translocation pore; other site
701347000580	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
701347000581	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
701347000582	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
701347000583	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_6; cd06315
701347000584	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
701347000585	putative ligand binding site [chemical binding]; other site
701347000586	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347000587	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347000588	TM-ABC transporter signature motif; other site
701347000589	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347000590	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347000591	Walker A/P-loop; other site
701347000592	ATP binding site [chemical binding]; other site
701347000593	Q-loop/lid; other site
701347000594	ABC transporter signature motif; other site
701347000595	Walker B; other site
701347000596	D-loop; other site
701347000597	H-loop/switch region; other site
701347000598	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347000599	Transcriptional regulator [Transcription]; Region: IclR; COG1414
701347000600	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
701347000601	Bacterial transcriptional regulator; Region: IclR; pfam01614
701347000602	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
701347000603	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347000604	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347000605	homodimer interface [polypeptide binding]; other site
701347000606	catalytic residue [active]
701347000607	alpha-amylase; Reviewed; Region: malS; PRK09505
701347000608	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
701347000609	active site
701347000610	catalytic site [active]
701347000611	hypothetical protein; Provisional; Region: PRK10356
701347000612	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
701347000613	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
701347000614	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
701347000615	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
701347000616	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
701347000617	putative dimerization interface [polypeptide binding]; other site
701347000618	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347000619	putative ligand binding site [chemical binding]; other site
701347000620	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347000621	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347000622	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347000623	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347000624	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347000625	TM-ABC transporter signature motif; other site
701347000626	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
701347000627	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347000628	Walker A/P-loop; other site
701347000629	ATP binding site [chemical binding]; other site
701347000630	Q-loop/lid; other site
701347000631	ABC transporter signature motif; other site
701347000632	Walker B; other site
701347000633	D-loop; other site
701347000634	H-loop/switch region; other site
701347000635	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347000636	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
701347000637	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
701347000638	putative ligand binding site [chemical binding]; other site
701347000639	xylose isomerase; Provisional; Region: PRK05474
701347000640	xylose isomerase; Region: xylose_isom_A; TIGR02630
701347000641	xylulokinase; Provisional; Region: PRK15027
701347000642	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
701347000643	N- and C-terminal domain interface [polypeptide binding]; other site
701347000644	active site
701347000645	MgATP binding site [chemical binding]; other site
701347000646	catalytic site [active]
701347000647	metal binding site [ion binding]; metal-binding site
701347000648	xylulose binding site [chemical binding]; other site
701347000649	homodimer interface [polypeptide binding]; other site
701347000650	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
701347000651	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
701347000652	Acyltransferase family; Region: Acyl_transf_3; pfam01757
701347000653	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
701347000654	YsaB-like lipoprotein; Region: YsaB; pfam13983
701347000655	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
701347000656	dimer interface [polypeptide binding]; other site
701347000657	motif 1; other site
701347000658	active site
701347000659	motif 2; other site
701347000660	motif 3; other site
701347000661	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
701347000662	DALR anticodon binding domain; Region: DALR_1; pfam05746
701347000663	anticodon binding site; other site
701347000664	tRNA binding surface [nucleotide binding]; other site
701347000665	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
701347000666	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347000667	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347000668	Predicted transcriptional regulator [Transcription]; Region: COG2944
701347000669	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347000670	salt bridge; other site
701347000671	non-specific DNA binding site [nucleotide binding]; other site
701347000672	sequence-specific DNA binding site [nucleotide binding]; other site
701347000673	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
701347000674	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
701347000675	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
701347000676	dimerization interface [polypeptide binding]; other site
701347000677	ligand binding site [chemical binding]; other site
701347000678	NADP binding site [chemical binding]; other site
701347000679	catalytic site [active]
701347000680	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000681	D-galactonate transporter; Region: 2A0114; TIGR00893
701347000682	putative substrate translocation pore; other site
701347000683	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347000684	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
701347000685	substrate binding site [chemical binding]; other site
701347000686	ATP binding site [chemical binding]; other site
701347000687	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
701347000688	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347000689	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347000690	DNA binding site [nucleotide binding]
701347000691	domain linker motif; other site
701347000692	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
701347000693	putative dimerization interface [polypeptide binding]; other site
701347000694	putative ligand binding site [chemical binding]; other site
701347000695	putative outer membrane lipoprotein; Provisional; Region: PRK10510
701347000696	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347000697	ligand binding site [chemical binding]; other site
701347000698	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
701347000699	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
701347000700	molybdopterin cofactor binding site [chemical binding]; other site
701347000701	substrate binding site [chemical binding]; other site
701347000702	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
701347000703	molybdopterin cofactor binding site; other site
701347000704	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347000705	Coenzyme A binding pocket [chemical binding]; other site
701347000706	Methyladenine glycosylase; Region: Adenine_glyco; cl01059
701347000707	Autotransporter beta-domain; Region: Autotransporter; cl17461
701347000708	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
701347000709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000710	putative substrate translocation pore; other site
701347000711	phosphoethanolamine transferase; Provisional; Region: PRK11560
701347000712	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
701347000713	Sulfatase; Region: Sulfatase; pfam00884
701347000714	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347000715	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
701347000716	peptide binding site [polypeptide binding]; other site
701347000717	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
701347000718	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347000719	dimer interface [polypeptide binding]; other site
701347000720	conserved gate region; other site
701347000721	putative PBP binding loops; other site
701347000722	ABC-ATPase subunit interface; other site
701347000723	dipeptide transporter; Provisional; Region: PRK10913
701347000724	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
701347000725	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347000726	dimer interface [polypeptide binding]; other site
701347000727	conserved gate region; other site
701347000728	putative PBP binding loops; other site
701347000729	ABC-ATPase subunit interface; other site
701347000730	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
701347000731	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347000732	Walker A/P-loop; other site
701347000733	ATP binding site [chemical binding]; other site
701347000734	Q-loop/lid; other site
701347000735	ABC transporter signature motif; other site
701347000736	Walker B; other site
701347000737	D-loop; other site
701347000738	H-loop/switch region; other site
701347000739	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
701347000740	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
701347000741	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347000742	Walker A/P-loop; other site
701347000743	ATP binding site [chemical binding]; other site
701347000744	Q-loop/lid; other site
701347000745	ABC transporter signature motif; other site
701347000746	Walker B; other site
701347000747	D-loop; other site
701347000748	H-loop/switch region; other site
701347000749	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
701347000750	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
701347000751	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
701347000752	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
701347000753	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
701347000754	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
701347000755	cell division protein; Provisional; Region: PRK10037
701347000756	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
701347000757	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
701347000758	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
701347000759	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
701347000760	DXD motif; other site
701347000761	PilZ domain; Region: PilZ; pfam07238
701347000762	cellulose synthase regulator protein; Provisional; Region: PRK11114
701347000763	endo-1,4-D-glucanase; Provisional; Region: PRK11097
701347000764	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
701347000765	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
701347000766	TPR motif; other site
701347000767	binding surface
701347000768	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347000769	TPR motif; other site
701347000770	binding surface
701347000771	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347000772	binding surface
701347000773	TPR motif; other site
701347000774	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347000775	TPR motif; other site
701347000776	binding surface
701347000777	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
701347000778	putative diguanylate cyclase; Provisional; Region: PRK13561
701347000779	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347000780	metal binding site [ion binding]; metal-binding site
701347000781	active site
701347000782	I-site; other site
701347000783	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347000784	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
701347000785	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
701347000786	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
701347000787	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
701347000788	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347000789	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
701347000790	substrate binding site [chemical binding]; other site
701347000791	ATP binding site [chemical binding]; other site
701347000792	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347000793	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000794	metabolite-proton symporter; Region: 2A0106; TIGR00883
701347000795	putative substrate translocation pore; other site
701347000796	inner membrane protein YhjD; Region: TIGR00766
701347000797	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347000798	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347000799	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
701347000800	putative effector binding pocket; other site
701347000801	putative dimerization interface [polypeptide binding]; other site
701347000802	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
701347000803	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
701347000804	NAD(P) binding site [chemical binding]; other site
701347000805	active site
701347000806	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
701347000807	Beta-lactamase; Region: Beta-lactamase; pfam00144
701347000808	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347000809	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347000810	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347000811	Fimbrial protein; Region: Fimbrial; cl01416
701347000812	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347000813	PapC N-terminal domain; Region: PapC_N; pfam13954
701347000814	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347000815	PapC C-terminal domain; Region: PapC_C; pfam13953
701347000816	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
701347000817	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347000818	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347000819	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347000820	glutathione reductase; Validated; Region: PRK06116
701347000821	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347000822	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347000823	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
701347000824	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
701347000825	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
701347000826	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
701347000827	active site
701347000828	oligopeptidase A; Provisional; Region: PRK10911
701347000829	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
701347000830	active site
701347000831	Zn binding site [ion binding]; other site
701347000832	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347000833	S-adenosylmethionine binding site [chemical binding]; other site
701347000834	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
701347000835	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347000836	putative substrate translocation pore; other site
701347000837	POT family; Region: PTR2; pfam00854
701347000838	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347000839	Ligand Binding Site [chemical binding]; other site
701347000840	universal stress protein UspB; Provisional; Region: PRK04960
701347000841	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
701347000842	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
701347000843	Predicted flavoproteins [General function prediction only]; Region: COG2081
701347000844	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347000845	Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076
701347000846	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347000847	catalytic residue [active]
701347000848	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
701347000849	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347000850	inhibitor-cofactor binding pocket; inhibition site
701347000851	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347000852	catalytic residue [active]
701347000853	aspartate kinase III; Validated; Region: PRK09084
701347000854	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
701347000855	nucleotide binding site [chemical binding]; other site
701347000856	substrate binding site [chemical binding]; other site
701347000857	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
701347000858	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
701347000859	FOG: CBS domain [General function prediction only]; Region: COG0517
701347000860	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
701347000861	Divalent cation transporter; Region: MgtE; pfam01769
701347000862	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
701347000863	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
701347000864	inhibitor-cofactor binding pocket; inhibition site
701347000865	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347000866	catalytic residue [active]
701347000867	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
701347000868	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
701347000869	Ligand binding site; other site
701347000870	Putative Catalytic site; other site
701347000871	DXD motif; other site
701347000872	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
701347000873	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
701347000874	active site
701347000875	substrate binding site [chemical binding]; other site
701347000876	cosubstrate binding site; other site
701347000877	catalytic site [active]
701347000878	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
701347000879	active site
701347000880	hexamer interface [polypeptide binding]; other site
701347000881	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
701347000882	NAD binding site [chemical binding]; other site
701347000883	substrate binding site [chemical binding]; other site
701347000884	active site
701347000885	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
701347000886	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
701347000887	putative active site [active]
701347000888	putative catalytic site [active]
701347000889	putative Zn binding site [ion binding]; other site
701347000890	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
701347000891	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
701347000892	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
701347000893	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
701347000894	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
701347000895	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
701347000896	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
701347000897	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
701347000898	dimer interface [polypeptide binding]; other site
701347000899	active site
701347000900	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
701347000901	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
701347000902	NAD(P) binding site [chemical binding]; other site
701347000903	active site
701347000904	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
701347000905	active site 2 [active]
701347000906	active site 1 [active]
701347000907	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
701347000908	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
701347000909	dimer interface [polypeptide binding]; other site
701347000910	active site
701347000911	Protein of unknown function (DUF3261); Region: DUF3261; pfam11659
701347000912	Predicted exporter [General function prediction only]; Region: COG4258
701347000913	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
701347000914	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
701347000915	active site
701347000916	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
701347000917	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
701347000918	Ligand binding site; other site
701347000919	Putative Catalytic site; other site
701347000920	DXD motif; other site
701347000921	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
701347000922	putative acyl-acceptor binding pocket; other site
701347000923	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
701347000924	active site 2 [active]
701347000925	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
701347000926	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
701347000927	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
701347000928	active site
701347000929	AMP binding site [chemical binding]; other site
701347000930	acyl-activating enzyme (AAE) consensus motif; other site
701347000931	acyl-activating enzyme (AAE) consensus motif; other site
701347000932	CoA binding site [chemical binding]; other site
701347000933	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
701347000934	CoA binding site [chemical binding]; other site
701347000935	Predicted membrane protein [Function unknown]; Region: COG4648
701347000936	acyl carrier protein; Provisional; Region: PRK05350
701347000937	Phosphopantetheine attachment site; Region: PP-binding; cl09936
701347000938	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
701347000939	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
701347000940	putative acyl-acceptor binding pocket; other site
701347000941	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
701347000942	hypothetical protein; Provisional; Region: PRK11615
701347000943	hypothetical protein; Provisional; Region: PRK11212
701347000944	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
701347000945	CPxP  motif; other site
701347000946	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
701347000947	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
701347000948	metal-binding site [ion binding]
701347000949	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347000950	Predicted membrane protein [Function unknown]; Region: COG3714
701347000951	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
701347000952	hypothetical protein; Provisional; Region: PRK10910
701347000953	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
701347000954	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347000955	S-adenosylmethionine binding site [chemical binding]; other site
701347000956	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
701347000957	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
701347000958	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
701347000959	P loop; other site
701347000960	GTP binding site [chemical binding]; other site
701347000961	cell division protein FtsE; Provisional; Region: PRK10908
701347000962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347000963	Walker A/P-loop; other site
701347000964	ATP binding site [chemical binding]; other site
701347000965	Q-loop/lid; other site
701347000966	ABC transporter signature motif; other site
701347000967	Walker B; other site
701347000968	D-loop; other site
701347000969	H-loop/switch region; other site
701347000970	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
701347000971	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
701347000972	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
701347000973	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
701347000974	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
701347000975	DNA binding residues [nucleotide binding]
701347000976	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
701347000977	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347000978	DNA-binding site [nucleotide binding]; DNA binding site
701347000979	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347000980	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347000981	homodimer interface [polypeptide binding]; other site
701347000982	catalytic residue [active]
701347000983	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
701347000984	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347000985	inhibitor-cofactor binding pocket; inhibition site
701347000986	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347000987	catalytic residue [active]
701347000988	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
701347000989	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
701347000990	dimerization interface [polypeptide binding]; other site
701347000991	ligand binding site [chemical binding]; other site
701347000992	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
701347000993	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
701347000994	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
701347000995	dimerization interface [polypeptide binding]; other site
701347000996	ligand binding site [chemical binding]; other site
701347000997	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347000998	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
701347000999	TM-ABC transporter signature motif; other site
701347001000	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
701347001001	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
701347001002	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
701347001003	TM-ABC transporter signature motif; other site
701347001004	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
701347001005	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
701347001006	Walker A/P-loop; other site
701347001007	ATP binding site [chemical binding]; other site
701347001008	Q-loop/lid; other site
701347001009	ABC transporter signature motif; other site
701347001010	Walker B; other site
701347001011	D-loop; other site
701347001012	H-loop/switch region; other site
701347001013	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
701347001014	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
701347001015	Walker A/P-loop; other site
701347001016	ATP binding site [chemical binding]; other site
701347001017	Q-loop/lid; other site
701347001018	ABC transporter signature motif; other site
701347001019	Walker B; other site
701347001020	D-loop; other site
701347001021	H-loop/switch region; other site
701347001022	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
701347001023	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
701347001024	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
701347001025	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001026	dimer interface [polypeptide binding]; other site
701347001027	conserved gate region; other site
701347001028	putative PBP binding loops; other site
701347001029	ABC-ATPase subunit interface; other site
701347001030	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
701347001031	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001032	dimer interface [polypeptide binding]; other site
701347001033	conserved gate region; other site
701347001034	putative PBP binding loops; other site
701347001035	ABC-ATPase subunit interface; other site
701347001036	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
701347001037	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
701347001038	Walker A/P-loop; other site
701347001039	ATP binding site [chemical binding]; other site
701347001040	Q-loop/lid; other site
701347001041	ABC transporter signature motif; other site
701347001042	Walker B; other site
701347001043	D-loop; other site
701347001044	H-loop/switch region; other site
701347001045	TOBE domain; Region: TOBE_2; pfam08402
701347001046	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
701347001047	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
701347001048	putative active site [active]
701347001049	catalytic site [active]
701347001050	putative metal binding site [ion binding]; other site
701347001051	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
701347001052	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
701347001053	putative acetyltransferase YhhY; Provisional; Region: PRK10140
701347001054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347001055	Coenzyme A binding pocket [chemical binding]; other site
701347001056	putative oxidoreductase; Provisional; Region: PRK10206
701347001057	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347001058	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
701347001059	Pirin-related protein [General function prediction only]; Region: COG1741
701347001060	Pirin; Region: Pirin; pfam02678
701347001061	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
701347001062	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347001063	DNA binding site [nucleotide binding]
701347001064	domain linker motif; other site
701347001065	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
701347001066	putative ligand binding site [chemical binding]; other site
701347001067	putative dimerization interface [polypeptide binding]; other site
701347001068	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
701347001069	ATP-binding site [chemical binding]; other site
701347001070	Gluconate-6-phosphate binding site [chemical binding]; other site
701347001071	low affinity gluconate transporter; Provisional; Region: PRK10472
701347001072	gluconate transporter; Region: gntP; TIGR00791
701347001073	putative antibiotic transporter; Provisional; Region: PRK10739
701347001074	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
701347001075	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
701347001076	glycogen branching enzyme; Provisional; Region: PRK05402
701347001077	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
701347001078	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
701347001079	active site
701347001080	catalytic site [active]
701347001081	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
701347001082	glycogen debranching enzyme; Provisional; Region: PRK03705
701347001083	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
701347001084	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
701347001085	active site
701347001086	catalytic site [active]
701347001087	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
701347001088	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
701347001089	ligand binding site; other site
701347001090	oligomer interface; other site
701347001091	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
701347001092	dimer interface [polypeptide binding]; other site
701347001093	N-terminal domain interface [polypeptide binding]; other site
701347001094	sulfate 1 binding site; other site
701347001095	glycogen synthase; Provisional; Region: glgA; PRK00654
701347001096	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
701347001097	ADP-binding pocket [chemical binding]; other site
701347001098	homodimer interface [polypeptide binding]; other site
701347001099	glycogen phosphorylase; Provisional; Region: PRK14986
701347001100	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
701347001101	homodimer interface [polypeptide binding]; other site
701347001102	active site pocket [active]
701347001103	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
701347001104	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
701347001105	active site residue [active]
701347001106	intramembrane serine protease GlpG; Provisional; Region: PRK10907
701347001107	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
701347001108	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
701347001109	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
701347001110	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
701347001111	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347001112	transcriptional regulator MalT; Provisional; Region: PRK04841
701347001113	AAA ATPase domain; Region: AAA_16; pfam13191
701347001114	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347001115	DNA binding residues [nucleotide binding]
701347001116	dimerization interface [polypeptide binding]; other site
701347001117	maltodextrin phosphorylase; Provisional; Region: PRK14985
701347001118	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
701347001119	active site pocket [active]
701347001120	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
701347001121	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
701347001122	high-affinity gluconate transporter; Provisional; Region: PRK14984
701347001123	gluconate transporter; Region: gntP; TIGR00791
701347001124	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
701347001125	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
701347001126	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
701347001127	DNA utilization protein GntX; Provisional; Region: PRK11595
701347001128	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347001129	active site
701347001130	carboxylesterase BioH; Provisional; Region: PRK10349
701347001131	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347001132	FeoC like transcriptional regulator; Region: FeoC; cl17677
701347001133	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
701347001134	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
701347001135	G1 box; other site
701347001136	GTP/Mg2+ binding site [chemical binding]; other site
701347001137	Switch I region; other site
701347001138	G2 box; other site
701347001139	G3 box; other site
701347001140	Switch II region; other site
701347001141	G4 box; other site
701347001142	G5 box; other site
701347001143	Nucleoside recognition; Region: Gate; pfam07670
701347001144	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
701347001145	Nucleoside recognition; Region: Gate; pfam07670
701347001146	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
701347001147	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
701347001148	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
701347001149	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
701347001150	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
701347001151	RNA binding site [nucleotide binding]; other site
701347001152	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
701347001153	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
701347001154	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
701347001155	osmolarity response regulator; Provisional; Region: ompR; PRK09468
701347001156	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347001157	active site
701347001158	phosphorylation site [posttranslational modification]
701347001159	intermolecular recognition site; other site
701347001160	dimerization interface [polypeptide binding]; other site
701347001161	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347001162	DNA binding site [nucleotide binding]
701347001163	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
701347001164	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347001165	dimerization interface [polypeptide binding]; other site
701347001166	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347001167	dimer interface [polypeptide binding]; other site
701347001168	phosphorylation site [posttranslational modification]
701347001169	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347001170	ATP binding site [chemical binding]; other site
701347001171	G-X-G motif; other site
701347001172	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
701347001173	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
701347001174	active site
701347001175	substrate-binding site [chemical binding]; other site
701347001176	metal-binding site [ion binding]
701347001177	ATP binding site [chemical binding]; other site
701347001178	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
701347001179	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
701347001180	dimerization interface [polypeptide binding]; other site
701347001181	domain crossover interface; other site
701347001182	redox-dependent activation switch; other site
701347001183	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347001184	RNA binding surface [nucleotide binding]; other site
701347001185	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
701347001186	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347001187	motif II; other site
701347001188	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
701347001189	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
701347001190	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
701347001191	ADP-ribose binding site [chemical binding]; other site
701347001192	dimer interface [polypeptide binding]; other site
701347001193	active site
701347001194	nudix motif; other site
701347001195	metal binding site [ion binding]; metal-binding site
701347001196	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
701347001197	Transglycosylase; Region: Transgly; pfam00912
701347001198	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
701347001199	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
701347001200	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
701347001201	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
701347001202	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
701347001203	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
701347001204	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
701347001205	shikimate kinase; Reviewed; Region: aroK; PRK00131
701347001206	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
701347001207	ADP binding site [chemical binding]; other site
701347001208	magnesium binding site [ion binding]; other site
701347001209	putative shikimate binding site; other site
701347001210	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
701347001211	active site
701347001212	dimer interface [polypeptide binding]; other site
701347001213	metal binding site [ion binding]; metal-binding site
701347001214	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
701347001215	cell division protein DamX; Validated; Region: PRK10905
701347001216	DNA adenine methylase; Provisional; Region: PRK10904
701347001217	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
701347001218	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
701347001219	substrate binding site [chemical binding]; other site
701347001220	hexamer interface [polypeptide binding]; other site
701347001221	metal binding site [ion binding]; metal-binding site
701347001222	phosphoglycolate phosphatase; Provisional; Region: PRK13222
701347001223	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347001224	motif II; other site
701347001225	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
701347001226	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
701347001227	active site
701347001228	HIGH motif; other site
701347001229	dimer interface [polypeptide binding]; other site
701347001230	KMSKS motif; other site
701347001231	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
701347001232	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
701347001233	dimer interface [polypeptide binding]; other site
701347001234	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
701347001235	active site
701347001236	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
701347001237	substrate binding site [chemical binding]; other site
701347001238	catalytic residue [active]
701347001239	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
701347001240	putative mutase; Provisional; Region: PRK12383
701347001241	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
701347001242	active site
701347001243	substrate binding pocket [chemical binding]; other site
701347001244	homodimer interaction site [polypeptide binding]; other site
701347001245	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
701347001246	Protein of unknown function; Region: YhfT; pfam10797
701347001247	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
701347001248	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347001249	catalytic residue [active]
701347001250	siroheme synthase; Provisional; Region: cysG; PRK10637
701347001251	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
701347001252	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
701347001253	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
701347001254	active site
701347001255	SAM binding site [chemical binding]; other site
701347001256	homodimer interface [polypeptide binding]; other site
701347001257	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
701347001258	nitrite reductase subunit NirD; Provisional; Region: PRK14989
701347001259	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347001260	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
701347001261	cytosine deaminase; Provisional; Region: PRK09230
701347001262	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
701347001263	active site
701347001264	putative transporter; Provisional; Region: PRK03699
701347001265	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347001266	putative substrate translocation pore; other site
701347001267	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
701347001268	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
701347001269	substrate binding site [chemical binding]; other site
701347001270	hypothetical protein; Provisional; Region: PRK10204
701347001271	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
701347001272	cell filamentation protein Fic; Provisional; Region: PRK10347
701347001273	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
701347001274	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
701347001275	glutamine binding [chemical binding]; other site
701347001276	catalytic triad [active]
701347001277	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
701347001278	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347001279	inhibitor-cofactor binding pocket; inhibition site
701347001280	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347001281	catalytic residue [active]
701347001282	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
701347001283	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
701347001284	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
701347001285	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
701347001286	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
701347001287	ligand binding site [chemical binding]; other site
701347001288	flexible hinge region; other site
701347001289	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
701347001290	putative switch regulator; other site
701347001291	non-specific DNA interactions [nucleotide binding]; other site
701347001292	DNA binding site [nucleotide binding]
701347001293	sequence specific DNA binding site [nucleotide binding]; other site
701347001294	putative cAMP binding site [chemical binding]; other site
701347001295	hypothetical protein; Provisional; Region: PRK10738
701347001296	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
701347001297	active site
701347001298	hypothetical protein; Provisional; Region: PRK04966
701347001299	putative hydrolase; Provisional; Region: PRK10985
701347001300	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
701347001301	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347001302	Walker A/P-loop; other site
701347001303	ATP binding site [chemical binding]; other site
701347001304	Q-loop/lid; other site
701347001305	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347001306	ABC transporter signature motif; other site
701347001307	Walker B; other site
701347001308	D-loop; other site
701347001309	ABC transporter; Region: ABC_tran_2; pfam12848
701347001310	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347001311	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
701347001312	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
701347001313	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
701347001314	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
701347001315	TrkA-N domain; Region: TrkA_N; pfam02254
701347001316	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
701347001317	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
701347001318	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
701347001319	phi X174 lysis protein; Provisional; Region: PRK02793
701347001320	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
701347001321	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
701347001322	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
701347001323	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
701347001324	YheO-like PAS domain; Region: PAS_6; pfam08348
701347001325	HTH domain; Region: HTH_22; pfam13309
701347001326	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
701347001327	sulfur relay protein TusC; Validated; Region: PRK00211
701347001328	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
701347001329	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
701347001330	S17 interaction site [polypeptide binding]; other site
701347001331	S8 interaction site; other site
701347001332	16S rRNA interaction site [nucleotide binding]; other site
701347001333	streptomycin interaction site [chemical binding]; other site
701347001334	23S rRNA interaction site [nucleotide binding]; other site
701347001335	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
701347001336	30S ribosomal protein S7; Validated; Region: PRK05302
701347001337	elongation factor G; Reviewed; Region: PRK00007
701347001338	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
701347001339	G1 box; other site
701347001340	putative GEF interaction site [polypeptide binding]; other site
701347001341	GTP/Mg2+ binding site [chemical binding]; other site
701347001342	Switch I region; other site
701347001343	G2 box; other site
701347001344	G3 box; other site
701347001345	Switch II region; other site
701347001346	G4 box; other site
701347001347	G5 box; other site
701347001348	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
701347001349	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
701347001350	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
701347001351	elongation factor Tu; Reviewed; Region: PRK00049
701347001352	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
701347001353	G1 box; other site
701347001354	GEF interaction site [polypeptide binding]; other site
701347001355	GTP/Mg2+ binding site [chemical binding]; other site
701347001356	Switch I region; other site
701347001357	G2 box; other site
701347001358	G3 box; other site
701347001359	Switch II region; other site
701347001360	G4 box; other site
701347001361	G5 box; other site
701347001362	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
701347001363	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
701347001364	Antibiotic Binding Site [chemical binding]; other site
701347001365	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
701347001366	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
701347001367	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
701347001368	heme binding site [chemical binding]; other site
701347001369	ferroxidase pore; other site
701347001370	ferroxidase diiron center [ion binding]; other site
701347001371	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
701347001372	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
701347001373	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
701347001374	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
701347001375	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
701347001376	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
701347001377	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
701347001378	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
701347001379	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
701347001380	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
701347001381	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
701347001382	protein-rRNA interface [nucleotide binding]; other site
701347001383	putative translocon binding site; other site
701347001384	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
701347001385	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
701347001386	G-X-X-G motif; other site
701347001387	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
701347001388	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
701347001389	23S rRNA interface [nucleotide binding]; other site
701347001390	5S rRNA interface [nucleotide binding]; other site
701347001391	putative antibiotic binding site [chemical binding]; other site
701347001392	L25 interface [polypeptide binding]; other site
701347001393	L27 interface [polypeptide binding]; other site
701347001394	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
701347001395	23S rRNA interface [nucleotide binding]; other site
701347001396	putative translocon interaction site; other site
701347001397	signal recognition particle (SRP54) interaction site; other site
701347001398	L23 interface [polypeptide binding]; other site
701347001399	trigger factor interaction site; other site
701347001400	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
701347001401	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
701347001402	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
701347001403	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
701347001404	RNA binding site [nucleotide binding]; other site
701347001405	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
701347001406	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
701347001407	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
701347001408	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
701347001409	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
701347001410	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
701347001411	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
701347001412	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
701347001413	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
701347001414	23S rRNA interface [nucleotide binding]; other site
701347001415	5S rRNA interface [nucleotide binding]; other site
701347001416	L27 interface [polypeptide binding]; other site
701347001417	L5 interface [polypeptide binding]; other site
701347001418	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
701347001419	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
701347001420	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
701347001421	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
701347001422	23S rRNA binding site [nucleotide binding]; other site
701347001423	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
701347001424	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
701347001425	SecY translocase; Region: SecY; pfam00344
701347001426	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
701347001427	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
701347001428	30S ribosomal protein S13; Region: bact_S13; TIGR03631
701347001429	30S ribosomal protein S11; Validated; Region: PRK05309
701347001430	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
701347001431	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
701347001432	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347001433	RNA binding surface [nucleotide binding]; other site
701347001434	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
701347001435	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
701347001436	alphaNTD homodimer interface [polypeptide binding]; other site
701347001437	alphaNTD - beta interaction site [polypeptide binding]; other site
701347001438	alphaNTD - beta' interaction site [polypeptide binding]; other site
701347001439	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
701347001440	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
701347001441	hypothetical protein; Provisional; Region: PRK10203
701347001442	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
701347001443	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
701347001444	DNA binding residues [nucleotide binding]
701347001445	dimer interface [polypeptide binding]; other site
701347001446	metal binding site [ion binding]; metal-binding site
701347001447	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
701347001448	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
701347001449	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
701347001450	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
701347001451	TrkA-N domain; Region: TrkA_N; pfam02254
701347001452	TrkA-C domain; Region: TrkA_C; pfam02080
701347001453	TrkA-N domain; Region: TrkA_N; pfam02254
701347001454	TrkA-C domain; Region: TrkA_C; pfam02080
701347001455	16S rRNA methyltransferase B; Provisional; Region: PRK10901
701347001456	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
701347001457	putative RNA binding site [nucleotide binding]; other site
701347001458	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347001459	S-adenosylmethionine binding site [chemical binding]; other site
701347001460	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
701347001461	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
701347001462	putative active site [active]
701347001463	substrate binding site [chemical binding]; other site
701347001464	putative cosubstrate binding site; other site
701347001465	catalytic site [active]
701347001466	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
701347001467	substrate binding site [chemical binding]; other site
701347001468	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
701347001469	active site
701347001470	catalytic residues [active]
701347001471	metal binding site [ion binding]; metal-binding site
701347001472	hypothetical protein; Provisional; Region: PRK10736
701347001473	DNA protecting protein DprA; Region: dprA; TIGR00732
701347001474	hypothetical protein; Validated; Region: PRK03430
701347001475	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
701347001476	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
701347001477	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
701347001478	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
701347001479	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
701347001480	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
701347001481	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
701347001482	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
701347001483	shikimate binding site; other site
701347001484	NAD(P) binding site [chemical binding]; other site
701347001485	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
701347001486	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
701347001487	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
701347001488	trimer interface [polypeptide binding]; other site
701347001489	putative metal binding site [ion binding]; other site
701347001490	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
701347001491	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347001492	Walker A/P-loop; other site
701347001493	ATP binding site [chemical binding]; other site
701347001494	Q-loop/lid; other site
701347001495	ABC transporter signature motif; other site
701347001496	Walker B; other site
701347001497	D-loop; other site
701347001498	H-loop/switch region; other site
701347001499	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; cl17274
701347001500	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347001501	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001502	dimer interface [polypeptide binding]; other site
701347001503	conserved gate region; other site
701347001504	putative PBP binding loops; other site
701347001505	ABC-ATPase subunit interface; other site
701347001506	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
701347001507	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001508	conserved gate region; other site
701347001509	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001510	putative PBP binding loops; other site
701347001511	dimer interface [polypeptide binding]; other site
701347001512	ABC-ATPase subunit interface; other site
701347001513	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347001514	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
701347001515	substrate binding pocket [chemical binding]; other site
701347001516	membrane-bound complex binding site; other site
701347001517	hinge residues; other site
701347001518	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
701347001519	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
701347001520	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
701347001521	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347001522	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347001523	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
701347001524	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347001525	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
701347001526	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
701347001527	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
701347001528	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
701347001529	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
701347001530	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
701347001531	FMN binding site [chemical binding]; other site
701347001532	active site
701347001533	catalytic residues [active]
701347001534	substrate binding site [chemical binding]; other site
701347001535	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
701347001536	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
701347001537	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
701347001538	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
701347001539	Na binding site [ion binding]; other site
701347001540	hypothetical protein; Provisional; Region: PRK10633
701347001541	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
701347001542	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
701347001543	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
701347001544	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
701347001545	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
701347001546	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
701347001547	carboxyltransferase (CT) interaction site; other site
701347001548	biotinylation site [posttranslational modification]; other site
701347001549	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
701347001550	Dehydroquinase class II; Region: DHquinase_II; pfam01220
701347001551	active site
701347001552	trimer interface [polypeptide binding]; other site
701347001553	dimer interface [polypeptide binding]; other site
701347001554	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
701347001555	TMAO/DMSO reductase; Reviewed; Region: PRK05363
701347001556	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
701347001557	Moco binding site; other site
701347001558	metal coordination site [ion binding]; other site
701347001559	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
701347001560	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
701347001561	NADP binding site [chemical binding]; other site
701347001562	dimer interface [polypeptide binding]; other site
701347001563	regulatory protein CsrD; Provisional; Region: PRK11059
701347001564	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347001565	metal binding site [ion binding]; metal-binding site
701347001566	active site
701347001567	I-site; other site
701347001568	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347001569	rod shape-determining protein MreB; Provisional; Region: PRK13927
701347001570	MreB and similar proteins; Region: MreB_like; cd10225
701347001571	nucleotide binding site [chemical binding]; other site
701347001572	Mg binding site [ion binding]; other site
701347001573	putative protofilament interaction site [polypeptide binding]; other site
701347001574	RodZ interaction site [polypeptide binding]; other site
701347001575	rod shape-determining protein MreC; Region: mreC; TIGR00219
701347001576	rod shape-determining protein MreC; Region: MreC; pfam04085
701347001577	rod shape-determining protein MreD; Provisional; Region: PRK11060
701347001578	Maf-like protein; Region: Maf; pfam02545
701347001579	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
701347001580	active site
701347001581	dimer interface [polypeptide binding]; other site
701347001582	ribonuclease G; Provisional; Region: PRK11712
701347001583	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
701347001584	homodimer interface [polypeptide binding]; other site
701347001585	oligonucleotide binding site [chemical binding]; other site
701347001586	hypothetical protein; Provisional; Region: PRK10899
701347001587	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
701347001588	protease TldD; Provisional; Region: tldD; PRK10735
701347001589	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
701347001590	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
701347001591	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347001592	transcriptional regulator; Provisional; Region: PRK10632
701347001593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347001594	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
701347001595	putative effector binding pocket; other site
701347001596	dimerization interface [polypeptide binding]; other site
701347001597	efflux system membrane protein; Provisional; Region: PRK11594
701347001598	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
701347001599	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347001600	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347001601	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
701347001602	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
701347001603	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
701347001604	RNAase interaction site [polypeptide binding]; other site
701347001605	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347001606	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347001607	arginine repressor; Provisional; Region: PRK05066
701347001608	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
701347001609	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
701347001610	malate dehydrogenase; Provisional; Region: PRK05086
701347001611	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
701347001612	NAD binding site [chemical binding]; other site
701347001613	dimerization interface [polypeptide binding]; other site
701347001614	Substrate binding site [chemical binding]; other site
701347001615	serine endoprotease; Provisional; Region: PRK10898
701347001616	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
701347001617	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
701347001618	serine endoprotease; Provisional; Region: PRK10139
701347001619	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
701347001620	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
701347001621	protein binding site [polypeptide binding]; other site
701347001622	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
701347001623	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
701347001624	hypothetical protein; Provisional; Region: PRK11677
701347001625	Predicted ATPase [General function prediction only]; Region: COG1485
701347001626	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
701347001627	23S rRNA interface [nucleotide binding]; other site
701347001628	L3 interface [polypeptide binding]; other site
701347001629	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
701347001630	stringent starvation protein A; Provisional; Region: sspA; PRK09481
701347001631	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
701347001632	C-terminal domain interface [polypeptide binding]; other site
701347001633	putative GSH binding site (G-site) [chemical binding]; other site
701347001634	dimer interface [polypeptide binding]; other site
701347001635	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
701347001636	dimer interface [polypeptide binding]; other site
701347001637	N-terminal domain interface [polypeptide binding]; other site
701347001638	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
701347001639	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; cl17322
701347001640	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
701347001641	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
701347001642	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347001643	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347001644	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347001645	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
701347001646	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
701347001647	active site
701347001648	dimer interface [polypeptide binding]; other site
701347001649	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
701347001650	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
701347001651	active site
701347001652	FMN binding site [chemical binding]; other site
701347001653	substrate binding site [chemical binding]; other site
701347001654	3Fe-4S cluster binding site [ion binding]; other site
701347001655	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
701347001656	domain interface; other site
701347001657	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
701347001658	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347001659	FeS/SAM binding site; other site
701347001660	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
701347001661	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347001662	putative active site [active]
701347001663	heme pocket [chemical binding]; other site
701347001664	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347001665	dimer interface [polypeptide binding]; other site
701347001666	phosphorylation site [posttranslational modification]
701347001667	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347001668	ATP binding site [chemical binding]; other site
701347001669	Mg2+ binding site [ion binding]; other site
701347001670	G-X-G motif; other site
701347001671	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347001672	active site
701347001673	phosphorylation site [posttranslational modification]
701347001674	intermolecular recognition site; other site
701347001675	dimerization interface [polypeptide binding]; other site
701347001676	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
701347001677	putative binding surface; other site
701347001678	active site
701347001679	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
701347001680	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
701347001681	conserved cys residue [active]
701347001682	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
701347001683	Transglycosylase; Region: Transgly; cl17702
701347001684	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347001685	dimerization domain swap beta strand [polypeptide binding]; other site
701347001686	regulatory protein interface [polypeptide binding]; other site
701347001687	active site
701347001688	regulatory phosphorylation site [posttranslational modification]; other site
701347001689	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
701347001690	AAA domain; Region: AAA_18; pfam13238
701347001691	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347001692	active site
701347001693	phosphorylation site [posttranslational modification]
701347001694	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
701347001695	30S subunit binding site; other site
701347001696	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
701347001697	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
701347001698	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
701347001699	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
701347001700	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
701347001701	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
701347001702	Walker A/P-loop; other site
701347001703	ATP binding site [chemical binding]; other site
701347001704	Q-loop/lid; other site
701347001705	ABC transporter signature motif; other site
701347001706	Walker B; other site
701347001707	D-loop; other site
701347001708	H-loop/switch region; other site
701347001709	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
701347001710	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
701347001711	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
701347001712	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
701347001713	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
701347001714	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
701347001715	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
701347001716	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
701347001717	putative active site [active]
701347001718	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
701347001719	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
701347001720	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
701347001721	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
701347001722	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
701347001723	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
701347001724	Walker A/P-loop; other site
701347001725	ATP binding site [chemical binding]; other site
701347001726	Q-loop/lid; other site
701347001727	ABC transporter signature motif; other site
701347001728	Walker B; other site
701347001729	D-loop; other site
701347001730	H-loop/switch region; other site
701347001731	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
701347001732	conserved hypothetical integral membrane protein; Region: TIGR00056
701347001733	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
701347001734	mce related protein; Region: MCE; pfam02470
701347001735	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
701347001736	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
701347001737	anti sigma factor interaction site; other site
701347001738	regulatory phosphorylation site [posttranslational modification]; other site
701347001739	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
701347001740	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
701347001741	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
701347001742	hinge; other site
701347001743	active site
701347001744	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
701347001745	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
701347001746	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
701347001747	substrate binding pocket [chemical binding]; other site
701347001748	chain length determination region; other site
701347001749	substrate-Mg2+ binding site; other site
701347001750	catalytic residues [active]
701347001751	aspartate-rich region 1; other site
701347001752	active site lid residues [active]
701347001753	aspartate-rich region 2; other site
701347001754	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
701347001755	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
701347001756	EamA-like transporter family; Region: EamA; pfam00892
701347001757	GTPase CgtA; Reviewed; Region: obgE; PRK12298
701347001758	GTP1/OBG; Region: GTP1_OBG; pfam01018
701347001759	Obg GTPase; Region: Obg; cd01898
701347001760	G1 box; other site
701347001761	GTP/Mg2+ binding site [chemical binding]; other site
701347001762	Switch I region; other site
701347001763	G2 box; other site
701347001764	G3 box; other site
701347001765	Switch II region; other site
701347001766	G4 box; other site
701347001767	G5 box; other site
701347001768	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
701347001769	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
701347001770	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
701347001771	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
701347001772	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
701347001773	RNA-binding protein YhbY; Provisional; Region: PRK10343
701347001774	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
701347001775	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347001776	S-adenosylmethionine binding site [chemical binding]; other site
701347001777	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
701347001778	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347001779	Walker A motif; other site
701347001780	ATP binding site [chemical binding]; other site
701347001781	Walker B motif; other site
701347001782	arginine finger; other site
701347001783	Peptidase family M41; Region: Peptidase_M41; pfam01434
701347001784	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
701347001785	dihydropteroate synthase; Region: DHPS; TIGR01496
701347001786	substrate binding pocket [chemical binding]; other site
701347001787	dimer interface [polypeptide binding]; other site
701347001788	inhibitor binding site; inhibition site
701347001789	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
701347001790	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
701347001791	active site
701347001792	substrate binding site [chemical binding]; other site
701347001793	metal binding site [ion binding]; metal-binding site
701347001794	Preprotein translocase SecG subunit; Region: SecG; pfam03840
701347001795	YfaZ precursor; Region: YfaZ; pfam07437
701347001796	outer membrane protein A; Reviewed; Region: PRK10808
701347001797	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
701347001798	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347001799	ligand binding site [chemical binding]; other site
701347001800	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
701347001801	argininosuccinate synthase; Validated; Region: PRK05370
701347001802	ribosome maturation protein RimP; Reviewed; Region: PRK00092
701347001803	Sm and related proteins; Region: Sm_like; cl00259
701347001804	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
701347001805	putative oligomer interface [polypeptide binding]; other site
701347001806	putative RNA binding site [nucleotide binding]; other site
701347001807	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
701347001808	NusA N-terminal domain; Region: NusA_N; pfam08529
701347001809	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
701347001810	RNA binding site [nucleotide binding]; other site
701347001811	homodimer interface [polypeptide binding]; other site
701347001812	NusA-like KH domain; Region: KH_5; pfam13184
701347001813	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
701347001814	G-X-X-G motif; other site
701347001815	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
701347001816	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
701347001817	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
701347001818	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
701347001819	translation initiation factor IF-2; Region: IF-2; TIGR00487
701347001820	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
701347001821	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
701347001822	G1 box; other site
701347001823	putative GEF interaction site [polypeptide binding]; other site
701347001824	GTP/Mg2+ binding site [chemical binding]; other site
701347001825	Switch I region; other site
701347001826	G2 box; other site
701347001827	G3 box; other site
701347001828	Switch II region; other site
701347001829	G4 box; other site
701347001830	G5 box; other site
701347001831	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
701347001832	Translation-initiation factor 2; Region: IF-2; pfam11987
701347001833	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
701347001834	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
701347001835	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
701347001836	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
701347001837	RNA binding site [nucleotide binding]; other site
701347001838	active site
701347001839	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
701347001840	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
701347001841	16S/18S rRNA binding site [nucleotide binding]; other site
701347001842	S13e-L30e interaction site [polypeptide binding]; other site
701347001843	25S rRNA binding site [nucleotide binding]; other site
701347001844	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
701347001845	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
701347001846	RNase E interface [polypeptide binding]; other site
701347001847	trimer interface [polypeptide binding]; other site
701347001848	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
701347001849	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
701347001850	RNase E interface [polypeptide binding]; other site
701347001851	trimer interface [polypeptide binding]; other site
701347001852	active site
701347001853	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
701347001854	putative nucleic acid binding region [nucleotide binding]; other site
701347001855	G-X-X-G motif; other site
701347001856	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
701347001857	RNA binding site [nucleotide binding]; other site
701347001858	domain interface; other site
701347001859	lipoprotein NlpI; Provisional; Region: PRK11189
701347001860	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347001861	binding surface
701347001862	TPR motif; other site
701347001863	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
701347001864	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
701347001865	ATP binding site [chemical binding]; other site
701347001866	Mg++ binding site [ion binding]; other site
701347001867	motif III; other site
701347001868	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347001869	nucleotide binding region [chemical binding]; other site
701347001870	ATP-binding site [chemical binding]; other site
701347001871	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
701347001872	putative RNA binding site [nucleotide binding]; other site
701347001873	tryptophan permease; Provisional; Region: PRK10483
701347001874	aromatic amino acid transport protein; Region: araaP; TIGR00837
701347001875	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
701347001876	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
701347001877	Walker A/P-loop; other site
701347001878	ATP binding site [chemical binding]; other site
701347001879	Q-loop/lid; other site
701347001880	ABC transporter signature motif; other site
701347001881	Walker B; other site
701347001882	D-loop; other site
701347001883	H-loop/switch region; other site
701347001884	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
701347001885	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001886	ABC-ATPase subunit interface; other site
701347001887	putative PBP binding loops; other site
701347001888	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
701347001889	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
701347001890	hypothetical protein; Provisional; Region: PRK10508
701347001891	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
701347001892	putative protease; Provisional; Region: PRK15447
701347001893	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
701347001894	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
701347001895	Peptidase family U32; Region: Peptidase_U32; pfam01136
701347001896	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
701347001897	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
701347001898	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347001899	Coenzyme A binding pocket [chemical binding]; other site
701347001900	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
701347001901	GIY-YIG motif/motif A; other site
701347001902	putative active site [active]
701347001903	putative metal binding site [ion binding]; other site
701347001904	hypothetical protein; Provisional; Region: PRK03467
701347001905	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
701347001906	NADH(P)-binding; Region: NAD_binding_10; pfam13460
701347001907	NAD binding site [chemical binding]; other site
701347001908	active site
701347001909	outer membrane lipoprotein; Provisional; Region: PRK11023
701347001910	BON domain; Region: BON; pfam04972
701347001911	BON domain; Region: BON; pfam04972
701347001912	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
701347001913	dimer interface [polypeptide binding]; other site
701347001914	active site
701347001915	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
701347001916	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
701347001917	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
701347001918	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
701347001919	putative ligand binding site [chemical binding]; other site
701347001920	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
701347001921	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
701347001922	putative SAM binding site [chemical binding]; other site
701347001923	putative homodimer interface [polypeptide binding]; other site
701347001924	Fic family protein [Function unknown]; Region: COG3177
701347001925	Fic/DOC family; Region: Fic; pfam02661
701347001926	HTH domain; Region: HTH_11; pfam08279
701347001927	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
701347001928	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347001929	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347001930	homodimer interface [polypeptide binding]; other site
701347001931	catalytic residue [active]
701347001932	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
701347001933	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347001934	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347001935	active site turn [active]
701347001936	phosphorylation site [posttranslational modification]
701347001937	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
701347001938	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
701347001939	intersubunit interface [polypeptide binding]; other site
701347001940	active site
701347001941	zinc binding site [ion binding]; other site
701347001942	Na+ binding site [ion binding]; other site
701347001943	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
701347001944	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
701347001945	dimer interface [polypeptide binding]; other site
701347001946	active site
701347001947	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
701347001948	putative active site [active]
701347001949	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
701347001950	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
701347001951	active site
701347001952	dimer interface [polypeptide binding]; other site
701347001953	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
701347001954	active pocket/dimerization site; other site
701347001955	active site
701347001956	phosphorylation site [posttranslational modification]
701347001957	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
701347001958	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
701347001959	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
701347001960	active site
701347001961	phosphorylation site [posttranslational modification]
701347001962	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
701347001963	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
701347001964	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
701347001965	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347001966	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
701347001967	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
701347001968	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347001969	fructokinase; Reviewed; Region: PRK09557
701347001970	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347001971	nucleotide binding site [chemical binding]; other site
701347001972	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347001973	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347001974	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
701347001975	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
701347001976	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
701347001977	Walker A/P-loop; other site
701347001978	ATP binding site [chemical binding]; other site
701347001979	Q-loop/lid; other site
701347001980	ABC transporter signature motif; other site
701347001981	Walker B; other site
701347001982	D-loop; other site
701347001983	H-loop/switch region; other site
701347001984	TOBE domain; Region: TOBE_2; pfam08402
701347001985	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
701347001986	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001987	dimer interface [polypeptide binding]; other site
701347001988	conserved gate region; other site
701347001989	putative PBP binding loops; other site
701347001990	ABC-ATPase subunit interface; other site
701347001991	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
701347001992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347001993	dimer interface [polypeptide binding]; other site
701347001994	conserved gate region; other site
701347001995	putative PBP binding loops; other site
701347001996	ABC-ATPase subunit interface; other site
701347001997	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
701347001998	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
701347001999	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
701347002000	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
701347002001	Walker A/P-loop; other site
701347002002	ATP binding site [chemical binding]; other site
701347002003	Q-loop/lid; other site
701347002004	ABC transporter signature motif; other site
701347002005	Walker B; other site
701347002006	D-loop; other site
701347002007	H-loop/switch region; other site
701347002008	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
701347002009	ABC-2 type transporter; Region: ABC2_membrane; cl17235
701347002010	Protein of unknown function (DUF3184); Region: DUF3184; pfam11380
701347002011	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
701347002012	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
701347002013	putative ADP-binding pocket [chemical binding]; other site
701347002014	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
701347002015	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347002016	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
701347002017	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002018	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347002019	dimerization interface [polypeptide binding]; other site
701347002020	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
701347002021	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
701347002022	tetramer interface [polypeptide binding]; other site
701347002023	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002024	catalytic residue [active]
701347002025	threonine/serine transporter TdcC; Provisional; Region: PRK13629
701347002026	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
701347002027	propionate/acetate kinase; Provisional; Region: PRK12379
701347002028	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
701347002029	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
701347002030	Pyruvate formate lyase 1; Region: PFL1; cd01678
701347002031	coenzyme A binding site [chemical binding]; other site
701347002032	active site
701347002033	catalytic residues [active]
701347002034	glycine loop; other site
701347002035	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
701347002036	homotrimer interaction site [polypeptide binding]; other site
701347002037	putative active site [active]
701347002038	L-serine dehydratase TdcG; Provisional; Region: PRK15040
701347002039	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
701347002040	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
701347002041	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
701347002042	dimer interface [polypeptide binding]; other site
701347002043	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
701347002044	serine transporter; Region: stp; TIGR00814
701347002045	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
701347002046	Pirin-related protein [General function prediction only]; Region: COG1741
701347002047	Pirin; Region: Pirin; pfam02678
701347002048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002049	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
701347002050	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347002051	dimerization interface [polypeptide binding]; other site
701347002052	Predicted membrane protein [Function unknown]; Region: COG3152
701347002053	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
701347002054	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
701347002055	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
701347002056	putative dimer interface [polypeptide binding]; other site
701347002057	N-terminal domain interface [polypeptide binding]; other site
701347002058	putative substrate binding pocket (H-site) [chemical binding]; other site
701347002059	Predicted membrane protein [Function unknown]; Region: COG2259
701347002060	YqjK-like protein; Region: YqjK; pfam13997
701347002061	Predicted membrane protein [Function unknown]; Region: COG5393
701347002062	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
701347002063	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
701347002064	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
701347002065	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
701347002066	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
701347002067	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
701347002068	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347002069	DNA-binding site [nucleotide binding]; DNA binding site
701347002070	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
701347002071	D-galactonate transporter; Region: 2A0114; TIGR00893
701347002072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347002073	putative substrate translocation pore; other site
701347002074	Glucuronate isomerase; Region: UxaC; pfam02614
701347002075	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
701347002076	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
701347002077	galactarate dehydratase; Region: galactar-dH20; TIGR03248
701347002078	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
701347002079	serine/threonine transporter SstT; Provisional; Region: PRK13628
701347002080	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
701347002081	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
701347002082	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347002083	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347002084	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
701347002085	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
701347002086	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347002087	S-adenosylmethionine binding site [chemical binding]; other site
701347002088	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
701347002089	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
701347002090	active site
701347002091	FMN binding site [chemical binding]; other site
701347002092	2,4-decadienoyl-CoA binding site; other site
701347002093	catalytic residue [active]
701347002094	4Fe-4S cluster binding site [ion binding]; other site
701347002095	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
701347002096	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347002097	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
701347002098	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
701347002099	putative N- and C-terminal domain interface [polypeptide binding]; other site
701347002100	putative active site [active]
701347002101	putative MgATP binding site [chemical binding]; other site
701347002102	catalytic site [active]
701347002103	metal binding site [ion binding]; metal-binding site
701347002104	putative carbohydrate binding site [chemical binding]; other site
701347002105	transcriptional regulator LsrR; Provisional; Region: PRK15418
701347002106	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
701347002107	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
701347002108	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347002109	Walker A/P-loop; other site
701347002110	ATP binding site [chemical binding]; other site
701347002111	Q-loop/lid; other site
701347002112	ABC transporter signature motif; other site
701347002113	Walker B; other site
701347002114	D-loop; other site
701347002115	H-loop/switch region; other site
701347002116	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347002117	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347002118	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347002119	TM-ABC transporter signature motif; other site
701347002120	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347002121	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347002122	TM-ABC transporter signature motif; other site
701347002123	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
701347002124	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
701347002125	ligand binding site [chemical binding]; other site
701347002126	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
701347002127	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
701347002128	putative active site; other site
701347002129	catalytic residue [active]
701347002130	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
701347002131	alpha-glucosidase; Provisional; Region: PRK10137
701347002132	Protein of unknown function, DUF608; Region: DUF608; pfam04685
701347002133	Trehalase; Region: Trehalase; cl17346
701347002134	inner membrane transporter YjeM; Provisional; Region: PRK15238
701347002135	inner membrane transporter YjeM; Provisional; Region: PRK15238
701347002136	Domain of unknown function (DUF386); Region: DUF386; cl01047
701347002137	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
701347002138	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
701347002139	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
701347002140	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
701347002141	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
701347002142	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
701347002143	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347002144	DNA binding site [nucleotide binding]
701347002145	domain linker motif; other site
701347002146	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
701347002147	putative dimerization interface [polypeptide binding]; other site
701347002148	putative ligand binding site [chemical binding]; other site
701347002149	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
701347002150	dimer interface [polypeptide binding]; other site
701347002151	putative tRNA-binding site [nucleotide binding]; other site
701347002152	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
701347002153	Fimbrial protein; Region: Fimbrial; cl01416
701347002154	Fimbrial protein; Region: Fimbrial; cl01416
701347002155	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347002156	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347002157	outer membrane usher protein; Provisional; Region: PRK15193
701347002158	PapC N-terminal domain; Region: PapC_N; pfam13954
701347002159	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347002160	PapC C-terminal domain; Region: PapC_C; pfam13953
701347002161	Fimbrial protein; Region: Fimbrial; cl01416
701347002162	Fimbrial protein; Region: Fimbrial; cl01416
701347002163	Fimbrial protein; Region: Fimbrial; cl01416
701347002164	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347002165	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347002166	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347002167	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
701347002168	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347002169	inhibitor-cofactor binding pocket; inhibition site
701347002170	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002171	catalytic residue [active]
701347002172	PAS fold; Region: PAS_3; pfam08447
701347002173	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347002174	putative active site [active]
701347002175	heme pocket [chemical binding]; other site
701347002176	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347002177	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347002178	dimer interface [polypeptide binding]; other site
701347002179	putative CheW interface [polypeptide binding]; other site
701347002180	Predicted transcriptional regulators [Transcription]; Region: COG1695
701347002181	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
701347002182	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
701347002183	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
701347002184	FAD binding pocket [chemical binding]; other site
701347002185	FAD binding motif [chemical binding]; other site
701347002186	phosphate binding motif [ion binding]; other site
701347002187	NAD binding pocket [chemical binding]; other site
701347002188	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
701347002189	HSP70 interaction site [polypeptide binding]; other site
701347002190	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
701347002191	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
701347002192	homodimer interface [polypeptide binding]; other site
701347002193	substrate-cofactor binding pocket; other site
701347002194	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002195	catalytic residue [active]
701347002196	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
701347002197	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
701347002198	dimer interface [polypeptide binding]; other site
701347002199	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002200	catalytic residue [active]
701347002201	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
701347002202	FOG: CBS domain [General function prediction only]; Region: COG0517
701347002203	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
701347002204	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
701347002205	Walker A/P-loop; other site
701347002206	ATP binding site [chemical binding]; other site
701347002207	Q-loop/lid; other site
701347002208	ABC transporter signature motif; other site
701347002209	Walker B; other site
701347002210	D-loop; other site
701347002211	H-loop/switch region; other site
701347002212	NIL domain; Region: NIL; pfam09383
701347002213	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347002214	putative PBP binding loops; other site
701347002215	dimer interface [polypeptide binding]; other site
701347002216	ABC-ATPase subunit interface; other site
701347002217	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
701347002218	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
701347002219	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
701347002220	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
701347002221	DsbD alpha interface [polypeptide binding]; other site
701347002222	catalytic residues [active]
701347002223	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
701347002224	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
701347002225	catalytic residues [active]
701347002226	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
701347002227	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
701347002228	Autotransporter beta-domain; Region: Autotransporter; smart00869
701347002229	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
701347002230	HSP70 interaction site [polypeptide binding]; other site
701347002231	chaperone protein DnaK; Region: prok_dnaK; TIGR02350
701347002232	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
701347002233	nucleotide binding site [chemical binding]; other site
701347002234	putative NEF/HSP70 interaction site [polypeptide binding]; other site
701347002235	SBD interface [polypeptide binding]; other site
701347002236	Surface antigen; Region: Bac_surface_Ag; pfam01103
701347002237	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
701347002238	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
701347002239	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
701347002240	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
701347002241	NAD(P) binding site [chemical binding]; other site
701347002242	active site
701347002243	Glycogen synthesis protein; Region: GlgS; cl11663
701347002244	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
701347002245	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
701347002246	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
701347002247	hypothetical protein; Reviewed; Region: PRK09588
701347002248	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
701347002249	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
701347002250	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
701347002251	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
701347002252	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347002253	Walker A motif; other site
701347002254	ATP binding site [chemical binding]; other site
701347002255	Walker B motif; other site
701347002256	arginine finger; other site
701347002257	integrase; Provisional; Region: PRK09692
701347002258	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
701347002259	active site
701347002260	DNA binding site [nucleotide binding]
701347002261	Int/Topo IB signature motif; other site
701347002262	Fic/DOC family; Region: Fic; pfam02661
701347002263	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
701347002264	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
701347002265	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
701347002266	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
701347002267	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
701347002268	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
701347002269	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
701347002270	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
701347002271	ATP binding site [chemical binding]; other site
701347002272	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
701347002273	putative Mg++ binding site [ion binding]; other site
701347002274	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
701347002275	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
701347002276	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
701347002277	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
701347002278	HsdM N-terminal domain; Region: HsdM_N; pfam12161
701347002279	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347002280	S-adenosylmethionine binding site [chemical binding]; other site
701347002281	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
701347002282	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
701347002283	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347002284	Walker A/P-loop; other site
701347002285	ATP binding site [chemical binding]; other site
701347002286	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
701347002287	putative active site [active]
701347002288	putative metal-binding site [ion binding]; other site
701347002289	Part of AAA domain; Region: AAA_19; pfam13245
701347002290	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
701347002291	Predicted GTPase [General function prediction only]; Region: COG3596
701347002292	YfjP GTPase; Region: YfjP; cd11383
701347002293	G1 box; other site
701347002294	GTP/Mg2+ binding site [chemical binding]; other site
701347002295	Switch I region; other site
701347002296	G2 box; other site
701347002297	Switch II region; other site
701347002298	G3 box; other site
701347002299	G4 box; other site
701347002300	G5 box; other site
701347002301	Domain of unknown function (DUF932); Region: DUF932; pfam06067
701347002302	Predicted transcriptional regulator [Transcription]; Region: COG2378
701347002303	WYL domain; Region: WYL; cl14852
701347002304	Antirestriction protein; Region: Antirestrict; pfam03230
701347002305	hypothetical protein; Reviewed; Region: PRK00024
701347002306	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
701347002307	MPN+ (JAMM) motif; other site
701347002308	Zinc-binding site [ion binding]; other site
701347002309	Protein of unknown function (DUF987); Region: DUF987; pfam06174
701347002310	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
701347002311	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
701347002312	Methyltransferase domain; Region: Methyltransf_27; pfam13708
701347002313	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
701347002314	active site
701347002315	SUMO-1 interface [polypeptide binding]; other site
701347002316	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
701347002317	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
701347002318	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
701347002319	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
701347002320	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
701347002321	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
701347002322	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
701347002323	DNA binding residues [nucleotide binding]
701347002324	DNA primase; Validated; Region: dnaG; PRK05667
701347002325	CHC2 zinc finger; Region: zf-CHC2; pfam01807
701347002326	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
701347002327	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
701347002328	active site
701347002329	metal binding site [ion binding]; metal-binding site
701347002330	interdomain interaction site; other site
701347002331	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
701347002332	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
701347002333	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
701347002334	UGMP family protein; Validated; Region: PRK09604
701347002335	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
701347002336	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
701347002337	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
701347002338	homooctamer interface [polypeptide binding]; other site
701347002339	active site
701347002340	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
701347002341	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
701347002342	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
701347002343	active site
701347002344	NTP binding site [chemical binding]; other site
701347002345	metal binding triad [ion binding]; metal-binding site
701347002346	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
701347002347	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
701347002348	Zn2+ binding site [ion binding]; other site
701347002349	Mg2+ binding site [ion binding]; other site
701347002350	SH3 domain-containing protein; Provisional; Region: PRK10884
701347002351	Bacterial SH3 domain homologues; Region: SH3b; smart00287
701347002352	Uncharacterized conserved protein [Function unknown]; Region: COG3025
701347002353	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
701347002354	putative active site [active]
701347002355	putative metal binding residues [ion binding]; other site
701347002356	signature motif; other site
701347002357	putative triphosphate binding site [ion binding]; other site
701347002358	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
701347002359	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
701347002360	metal binding triad; other site
701347002361	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
701347002362	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
701347002363	metal binding triad; other site
701347002364	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
701347002365	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
701347002366	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
701347002367	putative ribose interaction site [chemical binding]; other site
701347002368	putative ADP binding site [chemical binding]; other site
701347002369	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
701347002370	active site
701347002371	nucleotide binding site [chemical binding]; other site
701347002372	HIGH motif; other site
701347002373	KMSKS motif; other site
701347002374	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
701347002375	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
701347002376	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
701347002377	Fimbrial protein; Region: Fimbrial; pfam00419
701347002378	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347002379	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347002380	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347002381	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347002382	PapC N-terminal domain; Region: PapC_N; pfam13954
701347002383	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347002384	PapC C-terminal domain; Region: PapC_C; pfam13953
701347002385	Fimbrial protein; Region: Fimbrial; cl01416
701347002386	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
701347002387	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
701347002388	putative active site [active]
701347002389	metal binding site [ion binding]; metal-binding site
701347002390	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
701347002391	hypothetical protein; Provisional; Region: PRK11653
701347002392	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
701347002393	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
701347002394	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
701347002395	dimer interface [polypeptide binding]; other site
701347002396	ADP-ribose binding site [chemical binding]; other site
701347002397	active site
701347002398	nudix motif; other site
701347002399	metal binding site [ion binding]; metal-binding site
701347002400	putative dehydrogenase; Provisional; Region: PRK11039
701347002401	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
701347002402	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
701347002403	active site
701347002404	metal binding site [ion binding]; metal-binding site
701347002405	hexamer interface [polypeptide binding]; other site
701347002406	esterase YqiA; Provisional; Region: PRK11071
701347002407	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
701347002408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347002409	ATP binding site [chemical binding]; other site
701347002410	Mg2+ binding site [ion binding]; other site
701347002411	G-X-G motif; other site
701347002412	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
701347002413	anchoring element; other site
701347002414	dimer interface [polypeptide binding]; other site
701347002415	ATP binding site [chemical binding]; other site
701347002416	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
701347002417	active site
701347002418	metal binding site [ion binding]; metal-binding site
701347002419	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
701347002420	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
701347002421	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
701347002422	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
701347002423	DctM-like transporters; Region: DctM; pfam06808
701347002424	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
701347002425	Uncharacterized conserved protein [Function unknown]; Region: COG1359
701347002426	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
701347002427	sensor protein QseC; Provisional; Region: PRK10337
701347002428	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347002429	dimer interface [polypeptide binding]; other site
701347002430	phosphorylation site [posttranslational modification]
701347002431	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347002432	ATP binding site [chemical binding]; other site
701347002433	Mg2+ binding site [ion binding]; other site
701347002434	G-X-G motif; other site
701347002435	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
701347002436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347002437	active site
701347002438	phosphorylation site [posttranslational modification]
701347002439	intermolecular recognition site; other site
701347002440	dimerization interface [polypeptide binding]; other site
701347002441	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347002442	DNA binding site [nucleotide binding]
701347002443	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
701347002444	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347002445	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347002446	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
701347002447	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
701347002448	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
701347002449	CAP-like domain; other site
701347002450	active site
701347002451	primary dimer interface [polypeptide binding]; other site
701347002452	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
701347002453	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
701347002454	putative acyl-acceptor binding pocket; other site
701347002455	FtsI repressor; Provisional; Region: PRK10883
701347002456	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
701347002457	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
701347002458	hypothetical protein; Provisional; Region: PRK01254
701347002459	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
701347002460	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
701347002461	Lumazine-binding domain; Region: Lumazine_bd; pfam12870
701347002462	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347002463	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347002464	active site
701347002465	catalytic tetrad [active]
701347002466	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
701347002467	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
701347002468	dimer interface [polypeptide binding]; other site
701347002469	active site
701347002470	metal binding site [ion binding]; metal-binding site
701347002471	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
701347002472	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347002473	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347002474	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347002475	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
701347002476	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
701347002477	cystathionine beta-lyase; Provisional; Region: PRK08114
701347002478	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
701347002479	homodimer interface [polypeptide binding]; other site
701347002480	substrate-cofactor binding pocket; other site
701347002481	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002482	catalytic residue [active]
701347002483	biopolymer transport protein ExbB; Provisional; Region: PRK10414
701347002484	biopolymer transport protein ExbD; Provisional; Region: PRK11267
701347002485	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
701347002486	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347002487	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347002488	active site
701347002489	catalytic tetrad [active]
701347002490	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347002491	dimerization interface [polypeptide binding]; other site
701347002492	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347002493	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347002494	dimer interface [polypeptide binding]; other site
701347002495	putative CheW interface [polypeptide binding]; other site
701347002496	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
701347002497	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347002498	PAS fold; Region: PAS_3; pfam08447
701347002499	putative active site [active]
701347002500	heme pocket [chemical binding]; other site
701347002501	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347002502	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347002503	metal binding site [ion binding]; metal-binding site
701347002504	active site
701347002505	I-site; other site
701347002506	putative S-transferase; Provisional; Region: PRK11752
701347002507	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
701347002508	C-terminal domain interface [polypeptide binding]; other site
701347002509	GSH binding site (G-site) [chemical binding]; other site
701347002510	dimer interface [polypeptide binding]; other site
701347002511	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
701347002512	dimer interface [polypeptide binding]; other site
701347002513	N-terminal domain interface [polypeptide binding]; other site
701347002514	active site
701347002515	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347002516	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002517	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
701347002518	putative effector binding pocket; other site
701347002519	putative dimerization interface [polypeptide binding]; other site
701347002520	Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138
701347002521	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
701347002522	NAD binding site [chemical binding]; other site
701347002523	catalytic residues [active]
701347002524	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
701347002525	CHAP domain; Region: CHAP; pfam05257
701347002526	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
701347002527	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002528	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347002529	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002530	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347002531	dimerization interface [polypeptide binding]; other site
701347002532	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347002533	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347002534	DNA binding residues [nucleotide binding]
701347002535	dimerization interface [polypeptide binding]; other site
701347002536	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
701347002537	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347002538	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347002539	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
701347002540	Cupin domain; Region: Cupin_2; pfam07883
701347002541	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
701347002542	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347002543	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347002544	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; pfam10022
701347002545	galactoside permease; Reviewed; Region: lacY; PRK09528
701347002546	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347002547	putative substrate translocation pore; other site
701347002548	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
701347002549	DJ-1 family protein; Region: not_thiJ; TIGR01383
701347002550	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
701347002551	conserved cys residue [active]
701347002552	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
701347002553	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
701347002554	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
701347002555	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
701347002556	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
701347002557	acyl-activating enzyme (AAE) consensus motif; other site
701347002558	AMP binding site [chemical binding]; other site
701347002559	MBOAT, membrane-bound O-acyltransferase family; Region: MBOAT; cl00738
701347002560	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
701347002561	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
701347002562	heme-binding site [chemical binding]; other site
701347002563	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347002564	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347002565	metal binding site [ion binding]; metal-binding site
701347002566	active site
701347002567	I-site; other site
701347002568	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
701347002569	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347002570	putative active site [active]
701347002571	heme pocket [chemical binding]; other site
701347002572	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347002573	putative active site [active]
701347002574	heme pocket [chemical binding]; other site
701347002575	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347002576	metal binding site [ion binding]; metal-binding site
701347002577	active site
701347002578	I-site; other site
701347002579	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347002580	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347002581	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002582	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347002583	dimerization interface [polypeptide binding]; other site
701347002584	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
701347002585	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347002586	Coenzyme A binding pocket [chemical binding]; other site
701347002587	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
701347002588	Protein of unknown function (DUF554); Region: DUF554; pfam04474
701347002589	ornithine decarboxylase; Provisional; Region: PRK13578
701347002590	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
701347002591	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
701347002592	homodimer interface [polypeptide binding]; other site
701347002593	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002594	catalytic residue [active]
701347002595	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
701347002596	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
701347002597	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347002598	active site
701347002599	phosphorylation site [posttranslational modification]
701347002600	intermolecular recognition site; other site
701347002601	dimerization interface [polypeptide binding]; other site
701347002602	Transcriptional regulator; Region: CitT; pfam12431
701347002603	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
701347002604	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
701347002605	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347002606	putative active site [active]
701347002607	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347002608	ATP binding site [chemical binding]; other site
701347002609	Mg2+ binding site [ion binding]; other site
701347002610	G-X-G motif; other site
701347002611	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
701347002612	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
701347002613	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
701347002614	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
701347002615	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
701347002616	putative active site [active]
701347002617	(T/H)XGH motif; other site
701347002618	citrate lyase subunit gamma; Provisional; Region: PRK13253
701347002619	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
701347002620	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
701347002621	Coenzyme A transferase; Region: CoA_trans; cl17247
701347002622	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
701347002623	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
701347002624	nucleoside transporter; Region: 2A0110; TIGR00889
701347002625	murein transglycosylase C; Provisional; Region: mltC; PRK11671
701347002626	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
701347002627	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347002628	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347002629	catalytic residue [active]
701347002630	oxidative damage protection protein; Provisional; Region: PRK05408
701347002631	adenine DNA glycosylase; Provisional; Region: PRK10880
701347002632	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
701347002633	minor groove reading motif; other site
701347002634	helix-hairpin-helix signature motif; other site
701347002635	substrate binding pocket [chemical binding]; other site
701347002636	active site
701347002637	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
701347002638	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
701347002639	DNA binding and oxoG recognition site [nucleotide binding]
701347002640	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
701347002641	hypothetical protein; Provisional; Region: PRK11702
701347002642	hypothetical protein; Provisional; Region: PRK10626
701347002643	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
701347002644	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
701347002645	putative active site [active]
701347002646	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
701347002647	homodimer interface [polypeptide binding]; other site
701347002648	active site
701347002649	HemN family oxidoreductase; Provisional; Region: PRK05660
701347002650	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347002651	FeS/SAM binding site; other site
701347002652	HemN C-terminal domain; Region: HemN_C; pfam06969
701347002653	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
701347002654	active site
701347002655	dimerization interface [polypeptide binding]; other site
701347002656	hypothetical protein; Validated; Region: PRK05090
701347002657	YGGT family; Region: YGGT; pfam02325
701347002658	Predicted integral membrane protein [Function unknown]; Region: COG0762
701347002659	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
701347002660	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
701347002661	catalytic residue [active]
701347002662	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
701347002663	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
701347002664	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
701347002665	Walker A motif; other site
701347002666	Walker A motif; other site
701347002667	ATP binding site [chemical binding]; other site
701347002668	Walker B motif; other site
701347002669	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
701347002670	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347002671	DNA binding residues [nucleotide binding]
701347002672	dimerization interface [polypeptide binding]; other site
701347002673	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
701347002674	hypothetical protein; Validated; Region: PRK00228
701347002675	glutathione synthetase; Provisional; Region: PRK05246
701347002676	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
701347002677	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
701347002678	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
701347002679	RNA methyltransferase, RsmE family; Region: TIGR00046
701347002680	DNA-specific endonuclease I; Provisional; Region: PRK15137
701347002681	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
701347002682	hypothetical protein; Provisional; Region: PRK04860
701347002683	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
701347002684	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
701347002685	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347002686	putative substrate translocation pore; other site
701347002687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347002688	S-adenosylmethionine synthetase; Validated; Region: PRK05250
701347002689	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
701347002690	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
701347002691	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
701347002692	Virulence promoting factor; Region: YqgB; pfam11036
701347002693	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
701347002694	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
701347002695	dimer interface [polypeptide binding]; other site
701347002696	active site
701347002697	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
701347002698	catalytic residues [active]
701347002699	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
701347002700	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
701347002701	agmatinase; Region: agmatinase; TIGR01230
701347002702	oligomer interface [polypeptide binding]; other site
701347002703	putative active site [active]
701347002704	Mn binding site [ion binding]; other site
701347002705	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
701347002706	transketolase; Reviewed; Region: PRK12753
701347002707	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
701347002708	TPP-binding site [chemical binding]; other site
701347002709	dimer interface [polypeptide binding]; other site
701347002710	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
701347002711	PYR/PP interface [polypeptide binding]; other site
701347002712	dimer interface [polypeptide binding]; other site
701347002713	TPP binding site [chemical binding]; other site
701347002714	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
701347002715	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347002716	active site
701347002717	phosphorylation site [posttranslational modification]
701347002718	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
701347002719	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
701347002720	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
701347002721	active site
701347002722	P-loop; other site
701347002723	phosphorylation site [posttranslational modification]
701347002724	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
701347002725	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
701347002726	putative NAD(P) binding site [chemical binding]; other site
701347002727	catalytic Zn binding site [ion binding]; other site
701347002728	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
701347002729	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
701347002730	putative active site [active]
701347002731	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
701347002732	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
701347002733	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
701347002734	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
701347002735	active site
701347002736	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
701347002737	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
701347002738	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
701347002739	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
701347002740	Phosphoglycerate kinase; Region: PGK; pfam00162
701347002741	substrate binding site [chemical binding]; other site
701347002742	hinge regions; other site
701347002743	ADP binding site [chemical binding]; other site
701347002744	catalytic site [active]
701347002745	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
701347002746	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
701347002747	active site
701347002748	intersubunit interface [polypeptide binding]; other site
701347002749	zinc binding site [ion binding]; other site
701347002750	Na+ binding site [ion binding]; other site
701347002751	mechanosensitive channel MscS; Provisional; Region: PRK10334
701347002752	Mechanosensitive ion channel; Region: MS_channel; pfam00924
701347002753	arginine exporter protein; Provisional; Region: PRK09304
701347002754	Uncharacterized conserved protein [Function unknown]; Region: COG2968
701347002755	oxidative stress defense protein; Provisional; Region: PRK11087
701347002756	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002757	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347002758	LysR substrate binding domain; Region: LysR_substrate; pfam03466
701347002759	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
701347002760	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
701347002761	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
701347002762	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
701347002763	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347002764	substrate binding site [chemical binding]; other site
701347002765	oxyanion hole (OAH) forming residues; other site
701347002766	trimer interface [polypeptide binding]; other site
701347002767	membrane ATPase/protein kinase; Provisional; Region: PRK09435
701347002768	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
701347002769	Walker A; other site
701347002770	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
701347002771	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
701347002772	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
701347002773	active site
701347002774	substrate binding site [chemical binding]; other site
701347002775	coenzyme B12 binding site [chemical binding]; other site
701347002776	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
701347002777	B12 binding site [chemical binding]; other site
701347002778	cobalt ligand [ion binding]; other site
701347002779	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
701347002780	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002781	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
701347002782	putative dimerization interface [polypeptide binding]; other site
701347002783	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
701347002784	tetramer (dimer of dimers) interface [polypeptide binding]; other site
701347002785	active site
701347002786	dimer interface [polypeptide binding]; other site
701347002787	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
701347002788	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
701347002789	ligand binding site [chemical binding]; other site
701347002790	NAD binding site [chemical binding]; other site
701347002791	tetramer interface [polypeptide binding]; other site
701347002792	catalytic site [active]
701347002793	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
701347002794	L-serine binding site [chemical binding]; other site
701347002795	ACT domain interface; other site
701347002796	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
701347002797	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
701347002798	Z-ring-associated protein; Provisional; Region: PRK10972
701347002799	hypothetical protein; Reviewed; Region: PRK01736
701347002800	proline aminopeptidase P II; Provisional; Region: PRK10879
701347002801	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
701347002802	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
701347002803	active site
701347002804	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
701347002805	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
701347002806	oxidoreductase; Provisional; Region: PRK08013
701347002807	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
701347002808	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
701347002809	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
701347002810	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
701347002811	lipoyl attachment site [posttranslational modification]; other site
701347002812	glycine dehydrogenase; Provisional; Region: PRK05367
701347002813	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
701347002814	tetramer interface [polypeptide binding]; other site
701347002815	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002816	catalytic residue [active]
701347002817	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
701347002818	tetramer interface [polypeptide binding]; other site
701347002819	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347002820	catalytic residue [active]
701347002821	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
701347002822	classical (c) SDRs; Region: SDR_c; cd05233
701347002823	NAD(P) binding site [chemical binding]; other site
701347002824	active site
701347002825	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
701347002826	beta-galactosidase; Region: BGL; TIGR03356
701347002827	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347002828	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347002829	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347002830	putative active site [active]
701347002831	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
701347002832	hemolysin; Provisional; Region: PRK15087
701347002833	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
701347002834	putative global regulator; Reviewed; Region: PRK09559
701347002835	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
701347002836	hypothetical protein; Provisional; Region: PRK10878
701347002837	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
701347002838	flavodoxin FldB; Provisional; Region: PRK12359
701347002839	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
701347002840	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
701347002841	active site
701347002842	Int/Topo IB signature motif; other site
701347002843	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
701347002844	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
701347002845	dimerization domain [polypeptide binding]; other site
701347002846	dimer interface [polypeptide binding]; other site
701347002847	catalytic residues [active]
701347002848	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
701347002849	DHH family; Region: DHH; pfam01368
701347002850	DHHA1 domain; Region: DHHA1; pfam02272
701347002851	peptide chain release factor 2; Validated; Region: prfB; PRK00578
701347002852	This domain is found in peptide chain release factors; Region: PCRF; smart00937
701347002853	RF-1 domain; Region: RF-1; pfam00472
701347002854	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
701347002855	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
701347002856	dimer interface [polypeptide binding]; other site
701347002857	putative anticodon binding site; other site
701347002858	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
701347002859	motif 1; other site
701347002860	active site
701347002861	motif 2; other site
701347002862	motif 3; other site
701347002863	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347002864	Peptidase family M23; Region: Peptidase_M23; pfam01551
701347002865	Protein of unknown function (DUF3100); Region: DUF3100; pfam11299
701347002866	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
701347002867	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
701347002868	metal binding site [ion binding]; metal-binding site
701347002869	dimer interface [polypeptide binding]; other site
701347002870	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
701347002871	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002872	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347002873	dimerization interface [polypeptide binding]; other site
701347002874	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
701347002875	classical (c) SDRs; Region: SDR_c; cd05233
701347002876	NAD(P) binding site [chemical binding]; other site
701347002877	active site
701347002878	Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703
701347002879	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
701347002880	substrate binding pocket [chemical binding]; other site
701347002881	active site
701347002882	iron coordination sites [ion binding]; other site
701347002883	Predicted dehydrogenase [General function prediction only]; Region: COG0579
701347002884	hydroxyglutarate oxidase; Provisional; Region: PRK11728
701347002885	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
701347002886	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
701347002887	tetramerization interface [polypeptide binding]; other site
701347002888	NAD(P) binding site [chemical binding]; other site
701347002889	catalytic residues [active]
701347002890	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
701347002891	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
701347002892	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347002893	DNA-binding site [nucleotide binding]; DNA binding site
701347002894	FCD domain; Region: FCD; pfam07729
701347002895	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
701347002896	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
701347002897	catalytic triad [active]
701347002898	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347002899	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347002900	active site
701347002901	catalytic tetrad [active]
701347002902	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
701347002903	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
701347002904	putative acyltransferase; Provisional; Region: PRK05790
701347002905	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
701347002906	dimer interface [polypeptide binding]; other site
701347002907	active site
701347002908	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
701347002909	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
701347002910	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
701347002911	NADP binding site [chemical binding]; other site
701347002912	homodimer interface [polypeptide binding]; other site
701347002913	active site
701347002914	putative racemase; Provisional; Region: PRK10200
701347002915	aspartate racemase; Region: asp_race; TIGR00035
701347002916	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
701347002917	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347002918	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347002919	dimerization interface [polypeptide binding]; other site
701347002920	diaminopimelate decarboxylase; Provisional; Region: PRK11165
701347002921	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
701347002922	active site
701347002923	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
701347002924	substrate binding site [chemical binding]; other site
701347002925	catalytic residues [active]
701347002926	dimer interface [polypeptide binding]; other site
701347002927	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347002928	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347002929	DNA binding site [nucleotide binding]
701347002930	domain linker motif; other site
701347002931	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
701347002932	dimerization interface (closed form) [polypeptide binding]; other site
701347002933	ligand binding site [chemical binding]; other site
701347002934	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347002935	Coenzyme A binding pocket [chemical binding]; other site
701347002936	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
701347002937	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347002938	DNA binding site [nucleotide binding]
701347002939	domain linker motif; other site
701347002940	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
701347002941	dimerization interface (closed form) [polypeptide binding]; other site
701347002942	ligand binding site [chemical binding]; other site
701347002943	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
701347002944	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
701347002945	putative acyl-acceptor binding pocket; other site
701347002946	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
701347002947	acyl-activating enzyme (AAE) consensus motif; other site
701347002948	putative AMP binding site [chemical binding]; other site
701347002949	lysophospholipid transporter LplT; Provisional; Region: PRK11195
701347002950	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347002951	putative substrate translocation pore; other site
701347002952	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347002953	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347002954	active site
701347002955	catalytic tetrad [active]
701347002956	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
701347002957	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
701347002958	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
701347002959	putative DNA-binding cleft [nucleotide binding]; other site
701347002960	putative DNA clevage site; other site
701347002961	molecular lever; other site
701347002962	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
701347002963	putative active site [active]
701347002964	Ap4A binding site [chemical binding]; other site
701347002965	nudix motif; other site
701347002966	putative metal binding site [ion binding]; other site
701347002967	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
701347002968	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
701347002969	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
701347002970	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
701347002971	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
701347002972	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
701347002973	thymidylate synthase; Reviewed; Region: thyA; PRK01827
701347002974	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
701347002975	dimerization interface [polypeptide binding]; other site
701347002976	active site
701347002977	hypothetical protein; Provisional; Region: PRK10506
701347002978	hypothetical protein; Provisional; Region: PRK10557
701347002979	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
701347002980	Protein of unknown function (DUF2509); Region: DUF2509; cl11672
701347002981	hypothetical protein; Provisional; Region: PRK10332
701347002982	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
701347002983	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
701347002984	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
701347002985	protease3; Provisional; Region: PRK15101
701347002986	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
701347002987	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
701347002988	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
701347002989	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
701347002990	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
701347002991	AAA domain; Region: AAA_30; pfam13604
701347002992	Family description; Region: UvrD_C_2; pfam13538
701347002993	N-acetylglutamate synthase; Validated; Region: PRK05279
701347002994	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
701347002995	putative feedback inhibition sensing region; other site
701347002996	putative nucleotide binding site [chemical binding]; other site
701347002997	putative substrate binding site [chemical binding]; other site
701347002998	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347002999	Coenzyme A binding pocket [chemical binding]; other site
701347003000	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
701347003001	AMIN domain; Region: AMIN; pfam11741
701347003002	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
701347003003	active site
701347003004	metal binding site [ion binding]; metal-binding site
701347003005	murein transglycosylase A; Provisional; Region: mltA; PRK11162
701347003006	murein hydrolase B; Provisional; Region: PRK10760; cl17906
701347003007	MltA specific insert domain; Region: MltA; pfam03562
701347003008	3D domain; Region: 3D; pfam06725
701347003009	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
701347003010	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
701347003011	putative ATP binding site [chemical binding]; other site
701347003012	putative substrate interface [chemical binding]; other site
701347003013	Fe-S metabolism associated domain; Region: SufE; cl00951
701347003014	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
701347003015	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
701347003016	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347003017	catalytic residue [active]
701347003018	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
701347003019	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347003020	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
701347003021	dimerization interface [polypeptide binding]; other site
701347003022	substrate binding pocket [chemical binding]; other site
701347003023	hypothetical protein; Provisional; Region: PRK10873
701347003024	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
701347003025	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
701347003026	flap endonuclease-like protein; Provisional; Region: PRK09482
701347003027	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
701347003028	active site
701347003029	metal binding site 1 [ion binding]; metal-binding site
701347003030	putative 5' ssDNA interaction site; other site
701347003031	metal binding site 3; metal-binding site
701347003032	metal binding site 2 [ion binding]; metal-binding site
701347003033	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
701347003034	putative DNA binding site [nucleotide binding]; other site
701347003035	putative metal binding site [ion binding]; other site
701347003036	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
701347003037	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
701347003038	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
701347003039	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
701347003040	serine transporter; Region: stp; TIGR00814
701347003041	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
701347003042	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
701347003043	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
701347003044	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
701347003045	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
701347003046	SecY interacting protein Syd; Provisional; Region: PRK04968
701347003047	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
701347003048	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
701347003049	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
701347003050	probable active site [active]
701347003051	flavodoxin; Provisional; Region: PRK08105
701347003052	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
701347003053	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
701347003054	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347003055	dimerization interface [polypeptide binding]; other site
701347003056	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347003057	dimer interface [polypeptide binding]; other site
701347003058	phosphorylation site [posttranslational modification]
701347003059	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347003060	ATP binding site [chemical binding]; other site
701347003061	Mg2+ binding site [ion binding]; other site
701347003062	G-X-G motif; other site
701347003063	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
701347003064	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347003065	active site
701347003066	phosphorylation site [posttranslational modification]
701347003067	intermolecular recognition site; other site
701347003068	dimerization interface [polypeptide binding]; other site
701347003069	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
701347003070	putative binding surface; other site
701347003071	active site
701347003072	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
701347003073	TRAM domain; Region: TRAM; pfam01938
701347003074	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347003075	S-adenosylmethionine binding site [chemical binding]; other site
701347003076	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
701347003077	HD domain; Region: HD_4; pfam13328
701347003078	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
701347003079	synthetase active site [active]
701347003080	NTP binding site [chemical binding]; other site
701347003081	metal binding site [ion binding]; metal-binding site
701347003082	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
701347003083	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
701347003084	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
701347003085	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
701347003086	homodimer interface [polypeptide binding]; other site
701347003087	metal binding site [ion binding]; metal-binding site
701347003088	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
701347003089	homodimer interface [polypeptide binding]; other site
701347003090	active site
701347003091	putative chemical substrate binding site [chemical binding]; other site
701347003092	metal binding site [ion binding]; metal-binding site
701347003093	CTP synthetase; Validated; Region: pyrG; PRK05380
701347003094	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
701347003095	Catalytic site [active]
701347003096	active site
701347003097	UTP binding site [chemical binding]; other site
701347003098	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
701347003099	active site
701347003100	putative oxyanion hole; other site
701347003101	catalytic triad [active]
701347003102	enolase; Provisional; Region: eno; PRK00077
701347003103	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
701347003104	dimer interface [polypeptide binding]; other site
701347003105	metal binding site [ion binding]; metal-binding site
701347003106	substrate binding pocket [chemical binding]; other site
701347003107	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
701347003108	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
701347003109	NAD(P) binding site [chemical binding]; other site
701347003110	active site
701347003111	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347003112	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347003113	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347003114	putative active site [active]
701347003115	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
701347003116	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347003117	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347003118	active site turn [active]
701347003119	phosphorylation site [posttranslational modification]
701347003120	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
701347003121	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
701347003122	putative active site cavity [active]
701347003123	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
701347003124	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
701347003125	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
701347003126	active site
701347003127	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
701347003128	Flavodoxin; Region: Flavodoxin_1; pfam00258
701347003129	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
701347003130	FAD binding pocket [chemical binding]; other site
701347003131	FAD binding motif [chemical binding]; other site
701347003132	catalytic residues [active]
701347003133	NAD binding pocket [chemical binding]; other site
701347003134	phosphate binding motif [ion binding]; other site
701347003135	beta-alpha-beta structure motif; other site
701347003136	sulfite reductase subunit beta; Provisional; Region: PRK13504
701347003137	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
701347003138	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
701347003139	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
701347003140	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
701347003141	Active Sites [active]
701347003142	Hok/gef family; Region: HOK_GEF; pfam01848
701347003143	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
701347003144	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
701347003145	metal binding site [ion binding]; metal-binding site
701347003146	siroheme synthase; Provisional; Region: cysG; PRK10637
701347003147	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
701347003148	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
701347003149	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
701347003150	active site
701347003151	SAM binding site [chemical binding]; other site
701347003152	homodimer interface [polypeptide binding]; other site
701347003153	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
701347003154	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
701347003155	Active Sites [active]
701347003156	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
701347003157	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
701347003158	CysD dimerization site [polypeptide binding]; other site
701347003159	G1 box; other site
701347003160	putative GEF interaction site [polypeptide binding]; other site
701347003161	GTP/Mg2+ binding site [chemical binding]; other site
701347003162	Switch I region; other site
701347003163	G2 box; other site
701347003164	G3 box; other site
701347003165	Switch II region; other site
701347003166	G4 box; other site
701347003167	G5 box; other site
701347003168	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
701347003169	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
701347003170	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
701347003171	ligand-binding site [chemical binding]; other site
701347003172	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
701347003173	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
701347003174	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
701347003175	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
701347003176	substrate binding site; other site
701347003177	dimer interface; other site
701347003178	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
701347003179	homotrimer interaction site [polypeptide binding]; other site
701347003180	zinc binding site [ion binding]; other site
701347003181	CDP-binding sites; other site
701347003182	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
701347003183	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
701347003184	Permutation of conserved domain; other site
701347003185	active site
701347003186	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
701347003187	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
701347003188	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347003189	S-adenosylmethionine binding site [chemical binding]; other site
701347003190	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
701347003191	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347003192	Peptidase family M23; Region: Peptidase_M23; pfam01551
701347003193	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
701347003194	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
701347003195	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
701347003196	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
701347003197	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
701347003198	DNA binding residues [nucleotide binding]
701347003199	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347003200	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347003201	non-specific DNA binding site [nucleotide binding]; other site
701347003202	salt bridge; other site
701347003203	sequence-specific DNA binding site [nucleotide binding]; other site
701347003204	2TM domain; Region: 2TM; pfam13239
701347003205	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
701347003206	MutS domain I; Region: MutS_I; pfam01624
701347003207	MutS domain II; Region: MutS_II; pfam05188
701347003208	MutS domain III; Region: MutS_III; pfam05192
701347003209	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
701347003210	Walker A/P-loop; other site
701347003211	ATP binding site [chemical binding]; other site
701347003212	Q-loop/lid; other site
701347003213	ABC transporter signature motif; other site
701347003214	Walker B; other site
701347003215	D-loop; other site
701347003216	H-loop/switch region; other site
701347003217	Cache domain; Region: Cache_1; pfam02743
701347003218	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347003219	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347003220	dimer interface [polypeptide binding]; other site
701347003221	putative CheW interface [polypeptide binding]; other site
701347003222	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
701347003223	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
701347003224	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
701347003225	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
701347003226	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347003227	FeS/SAM binding site; other site
701347003228	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
701347003229	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
701347003230	Sulfatase; Region: Sulfatase; pfam00884
701347003231	Acyltransferase family; Region: Acyl_transf_3; pfam01757
701347003232	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
701347003233	putative cyanate transporter; Provisional; Region: cynX; PRK09705
701347003234	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003235	putative substrate translocation pore; other site
701347003236	cyanate hydratase; Validated; Region: PRK02866
701347003237	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
701347003238	oligomer interface [polypeptide binding]; other site
701347003239	active site
701347003240	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
701347003241	active site clefts [active]
701347003242	zinc binding site [ion binding]; other site
701347003243	dimer interface [polypeptide binding]; other site
701347003244	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
701347003245	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347003246	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
701347003247	dimerization interface [polypeptide binding]; other site
701347003248	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
701347003249	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
701347003250	molybdenum-pterin binding domain; Region: Mop; TIGR00638
701347003251	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
701347003252	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
701347003253	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
701347003254	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
701347003255	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347003256	Walker A motif; other site
701347003257	ATP binding site [chemical binding]; other site
701347003258	Walker B motif; other site
701347003259	arginine finger; other site
701347003260	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
701347003261	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
701347003262	dimerization interface [polypeptide binding]; other site
701347003263	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
701347003264	ATP binding site [chemical binding]; other site
701347003265	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
701347003266	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
701347003267	hydrogenase assembly chaperone; Provisional; Region: PRK10409
701347003268	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
701347003269	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
701347003270	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
701347003271	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
701347003272	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
701347003273	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
701347003274	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
701347003275	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
701347003276	NADH dehydrogenase; Region: NADHdh; cl00469
701347003277	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
701347003278	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
701347003279	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
701347003280	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
701347003281	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347003282	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
701347003283	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
701347003284	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
701347003285	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
701347003286	nickel binding site [ion binding]; other site
701347003287	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
701347003288	beta-galactosidase; Region: BGL; TIGR03356
701347003289	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
701347003290	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347003291	active site turn [active]
701347003292	phosphorylation site [posttranslational modification]
701347003293	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
701347003294	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347003295	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347003296	DNA binding site [nucleotide binding]
701347003297	domain linker motif; other site
701347003298	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
701347003299	dimerization interface (closed form) [polypeptide binding]; other site
701347003300	ligand binding site [chemical binding]; other site
701347003301	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
701347003302	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
701347003303	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
701347003304	Acylphosphatase; Region: Acylphosphatase; pfam00708
701347003305	HypF finger; Region: zf-HYPF; pfam07503
701347003306	HypF finger; Region: zf-HYPF; pfam07503
701347003307	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
701347003308	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
701347003309	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
701347003310	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
701347003311	catalytic residues [active]
701347003312	hinge region; other site
701347003313	alpha helical domain; other site
701347003314	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
701347003315	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
701347003316	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
701347003317	DXD motif; other site
701347003318	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
701347003319	putative trimer interface [polypeptide binding]; other site
701347003320	putative CoA binding site [chemical binding]; other site
701347003321	transcriptional regulator SirC; Provisional; Region: PRK15044
701347003322	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347003323	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
701347003324	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347003325	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347003326	catalytic residue [active]
701347003327	Toxin-coregulated pilus subunit TcpA; Region: TcpA; pfam05946
701347003328	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
701347003329	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
701347003330	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
701347003331	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
701347003332	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
701347003333	Type II/IV secretion system protein; Region: T2SE; pfam00437
701347003334	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
701347003335	Walker A motif; other site
701347003336	ATP binding site [chemical binding]; other site
701347003337	Walker B motif; other site
701347003338	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
701347003339	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
701347003340	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
701347003341	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
701347003342	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
701347003343	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347003344	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347003345	DNA binding residues [nucleotide binding]
701347003346	dimerization interface [polypeptide binding]; other site
701347003347	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
701347003348	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347003349	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347003350	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
701347003351	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
701347003352	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
701347003353	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
701347003354	iron binding site [ion binding]; other site
701347003355	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
701347003356	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
701347003357	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347003358	Walker A motif; other site
701347003359	ATP binding site [chemical binding]; other site
701347003360	Walker B motif; other site
701347003361	arginine finger; other site
701347003362	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
701347003363	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
701347003364	putative active site [active]
701347003365	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
701347003366	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
701347003367	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
701347003368	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347003369	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
701347003370	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
701347003371	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
701347003372	putative NAD(P) binding site [chemical binding]; other site
701347003373	active site
701347003374	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
701347003375	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
701347003376	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
701347003377	Nucleoside recognition; Region: Gate; pfam07670
701347003378	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
701347003379	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
701347003380	Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane]; Region: MltB; COG2951
701347003381	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347003382	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347003383	hypothetical protein; Validated; Region: PRK03661
701347003384	recombinase A; Provisional; Region: recA; PRK09354
701347003385	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
701347003386	hexamer interface [polypeptide binding]; other site
701347003387	Walker A motif; other site
701347003388	ATP binding site [chemical binding]; other site
701347003389	Walker B motif; other site
701347003390	recombination regulator RecX; Reviewed; Region: recX; PRK00117
701347003391	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
701347003392	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
701347003393	motif 1; other site
701347003394	active site
701347003395	motif 2; other site
701347003396	motif 3; other site
701347003397	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
701347003398	DHHA1 domain; Region: DHHA1; pfam02272
701347003399	carbon storage regulator; Provisional; Region: PRK01712
701347003400	BON domain; Region: BON; pfam04972
701347003401	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
701347003402	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347003403	motif II; other site
701347003404	Predicted membrane protein [Function unknown]; Region: COG1238
701347003405	glutamate--cysteine ligase; Provisional; Region: PRK02107
701347003406	S-ribosylhomocysteinase; Provisional; Region: PRK02260
701347003407	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
701347003408	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003409	putative substrate translocation pore; other site
701347003410	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003411	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
701347003412	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347003413	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347003414	transcriptional repressor MprA; Provisional; Region: PRK10870
701347003415	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
701347003416	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
701347003417	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003418	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
701347003419	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
701347003420	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
701347003421	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347003422	dimer interface [polypeptide binding]; other site
701347003423	conserved gate region; other site
701347003424	putative PBP binding loops; other site
701347003425	ABC-ATPase subunit interface; other site
701347003426	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
701347003427	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
701347003428	Walker A/P-loop; other site
701347003429	ATP binding site [chemical binding]; other site
701347003430	Q-loop/lid; other site
701347003431	ABC transporter signature motif; other site
701347003432	Walker B; other site
701347003433	D-loop; other site
701347003434	H-loop/switch region; other site
701347003435	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
701347003436	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
701347003437	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
701347003438	dimer interface [polypeptide binding]; other site
701347003439	putative radical transfer pathway; other site
701347003440	diiron center [ion binding]; other site
701347003441	tyrosyl radical; other site
701347003442	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
701347003443	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
701347003444	Class I ribonucleotide reductase; Region: RNR_I; cd01679
701347003445	active site
701347003446	dimer interface [polypeptide binding]; other site
701347003447	catalytic residues [active]
701347003448	effector binding site; other site
701347003449	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
701347003450	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
701347003451	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
701347003452	catalytic residues [active]
701347003453	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
701347003454	Uncharacterized conserved protein [Function unknown]; Region: COG2128
701347003455	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
701347003456	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347003457	DNA-binding site [nucleotide binding]; DNA binding site
701347003458	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347003459	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347003460	homodimer interface [polypeptide binding]; other site
701347003461	catalytic residue [active]
701347003462	hypothetical protein; Provisional; Region: PRK10556
701347003463	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
701347003464	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
701347003465	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
701347003466	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
701347003467	LysE type translocator; Region: LysE; cl00565
701347003468	HdeA/HdeB family; Region: HdeA; cl05752
701347003469	Predicted acetyltransferase [General function prediction only]; Region: COG2388
701347003470	Uncharacterized conserved protein [Function unknown]; Region: COG3592
701347003471	magnesium transport protein MgtC; Provisional; Region: PRK15385
701347003472	MgtC family; Region: MgtC; pfam02308
701347003473	magnesium-transporting ATPase; Provisional; Region: PRK15122
701347003474	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
701347003475	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347003476	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347003477	motif II; other site
701347003478	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
701347003479	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
701347003480	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347003481	active site
701347003482	phosphorylation site [posttranslational modification]
701347003483	intermolecular recognition site; other site
701347003484	dimerization interface [polypeptide binding]; other site
701347003485	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347003486	DNA binding residues [nucleotide binding]
701347003487	dimerization interface [polypeptide binding]; other site
701347003488	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
701347003489	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347003490	substrate binding pocket [chemical binding]; other site
701347003491	membrane-bound complex binding site; other site
701347003492	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
701347003493	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347003494	substrate binding pocket [chemical binding]; other site
701347003495	membrane-bound complex binding site; other site
701347003496	hinge residues; other site
701347003497	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347003498	dimer interface [polypeptide binding]; other site
701347003499	phosphorylation site [posttranslational modification]
701347003500	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347003501	ATP binding site [chemical binding]; other site
701347003502	Mg2+ binding site [ion binding]; other site
701347003503	G-X-G motif; other site
701347003504	Response regulator receiver domain; Region: Response_reg; pfam00072
701347003505	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347003506	active site
701347003507	phosphorylation site [posttranslational modification]
701347003508	intermolecular recognition site; other site
701347003509	dimerization interface [polypeptide binding]; other site
701347003510	Hpt domain; Region: Hpt; pfam01627
701347003511	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347003512	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347003513	DNA binding residues [nucleotide binding]
701347003514	dimerization interface [polypeptide binding]; other site
701347003515	Fimbrial protein; Region: Fimbrial; cl01416
701347003516	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347003517	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347003518	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347003519	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347003520	PapC N-terminal domain; Region: PapC_N; pfam13954
701347003521	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347003522	PapC C-terminal domain; Region: PapC_C; pfam13953
701347003523	Fimbrial protein; Region: Fimbrial; pfam00419
701347003524	EAL domain; Region: EAL; pfam00563
701347003525	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
701347003526	MULE transposase domain; Region: MULE; pfam10551
701347003527	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
701347003528	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
701347003529	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
701347003530	homodimer interface [polypeptide binding]; other site
701347003531	substrate-cofactor binding pocket; other site
701347003532	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347003533	catalytic residue [active]
701347003534	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
701347003535	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347003536	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347003537	non-specific DNA binding site [nucleotide binding]; other site
701347003538	salt bridge; other site
701347003539	sequence-specific DNA binding site [nucleotide binding]; other site
701347003540	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347003541	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347003542	non-specific DNA binding site [nucleotide binding]; other site
701347003543	salt bridge; other site
701347003544	sequence-specific DNA binding site [nucleotide binding]; other site
701347003545	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
701347003546	Thymidylate synthase; Region: Thymidylat_synt; pfam00303
701347003547	dimerization interface [polypeptide binding]; other site
701347003548	active site
701347003549	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
701347003550	Domain of unknown function (DUF955); Region: DUF955; pfam06114
701347003551	Domain of unknown function (DUF4263); Region: DUF4263; pfam14082
701347003552	T5orf172 domain; Region: T5orf172; pfam10544
701347003553	DEAD-like helicases superfamily; Region: DEXDc; smart00487
701347003554	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347003555	ATP binding site [chemical binding]; other site
701347003556	putative Mg++ binding site [ion binding]; other site
701347003557	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
701347003558	Methyltransferase domain; Region: Methyltransf_26; pfam13659
701347003559	putative transposase OrfB; Reviewed; Region: PHA02517
701347003560	HTH-like domain; Region: HTH_21; pfam13276
701347003561	Integrase core domain; Region: rve; pfam00665
701347003562	Integrase core domain; Region: rve_3; pfam13683
701347003563	Transposase; Region: HTH_Tnp_1; pfam01527
701347003564	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
701347003565	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
701347003566	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
701347003567	integrase; Provisional; Region: PRK09692
701347003568	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
701347003569	active site
701347003570	Int/Topo IB signature motif; other site
701347003571	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
701347003572	SmpB-tmRNA interface; other site
701347003573	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
701347003574	putative coenzyme Q binding site [chemical binding]; other site
701347003575	hypothetical protein; Validated; Region: PRK01777
701347003576	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
701347003577	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
701347003578	recombination and repair protein; Provisional; Region: PRK10869
701347003579	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
701347003580	Walker A/P-loop; other site
701347003581	ATP binding site [chemical binding]; other site
701347003582	Q-loop/lid; other site
701347003583	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
701347003584	ABC transporter signature motif; other site
701347003585	Walker B; other site
701347003586	D-loop; other site
701347003587	H-loop/switch region; other site
701347003588	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
701347003589	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
701347003590	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
701347003591	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
701347003592	dimer interface [polypeptide binding]; other site
701347003593	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
701347003594	hypothetical protein; Provisional; Region: PRK11573
701347003595	Domain of unknown function DUF21; Region: DUF21; pfam01595
701347003596	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
701347003597	Transporter associated domain; Region: CorC_HlyC; smart01091
701347003598	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
701347003599	signal recognition particle protein; Provisional; Region: PRK10867
701347003600	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
701347003601	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
701347003602	P loop; other site
701347003603	GTP binding site [chemical binding]; other site
701347003604	Signal peptide binding domain; Region: SRP_SPB; pfam02978
701347003605	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
701347003606	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
701347003607	RimM N-terminal domain; Region: RimM; pfam01782
701347003608	PRC-barrel domain; Region: PRC; pfam05239
701347003609	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
701347003610	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
701347003611	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
701347003612	tail protein; Provisional; Region: D; PHA02561
701347003613	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
701347003614	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
701347003615	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
701347003616	major tail tube protein; Provisional; Region: FII; PHA02600
701347003617	major tail sheath protein; Provisional; Region: FI; PHA02560
701347003618	multiple promoter invertase; Provisional; Region: mpi; PRK13413
701347003619	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
701347003620	catalytic residues [active]
701347003621	catalytic nucleophile [active]
701347003622	Presynaptic Site I dimer interface [polypeptide binding]; other site
701347003623	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
701347003624	Synaptic Flat tetramer interface [polypeptide binding]; other site
701347003625	Synaptic Site I dimer interface [polypeptide binding]; other site
701347003626	DNA binding site [nucleotide binding]
701347003627	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
701347003628	DNA-binding interface [nucleotide binding]; DNA binding site
701347003629	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
701347003630	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
701347003631	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
701347003632	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
701347003633	baseplate assembly protein; Provisional; Region: J; PHA02568
701347003634	baseplate wedge subunit; Provisional; Region: W; PHA02516
701347003635	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
701347003636	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
701347003637	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
701347003638	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
701347003639	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
701347003640	catalytic residues [active]
701347003641	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
701347003642	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
701347003643	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
701347003644	DksA-like zinc finger domain containing protein; Region: PHA00080
701347003645	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
701347003646	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
701347003647	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
701347003648	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
701347003649	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
701347003650	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
701347003651	putative outer membrane lipoprotein; Provisional; Region: PRK09967
701347003652	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347003653	ligand binding site [chemical binding]; other site
701347003654	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
701347003655	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347003656	metal binding site [ion binding]; metal-binding site
701347003657	active site
701347003658	I-site; other site
701347003659	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
701347003660	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
701347003661	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
701347003662	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
701347003663	Chorismate mutase type II; Region: CM_2; cl00693
701347003664	prephenate dehydrogenase; Validated; Region: PRK08507
701347003665	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
701347003666	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
701347003667	Prephenate dehydratase; Region: PDT; pfam00800
701347003668	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
701347003669	putative L-Phe binding site [chemical binding]; other site
701347003670	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
701347003671	30S subunit binding site; other site
701347003672	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
701347003673	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
701347003674	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347003675	RNA binding surface [nucleotide binding]; other site
701347003676	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
701347003677	active site
701347003678	hypothetical protein; Provisional; Region: PRK10723
701347003679	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
701347003680	protein disaggregation chaperone; Provisional; Region: PRK10865
701347003681	Clp amino terminal domain; Region: Clp_N; pfam02861
701347003682	Clp amino terminal domain; Region: Clp_N; pfam02861
701347003683	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347003684	Walker A motif; other site
701347003685	ATP binding site [chemical binding]; other site
701347003686	Walker B motif; other site
701347003687	arginine finger; other site
701347003688	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347003689	Walker A motif; other site
701347003690	ATP binding site [chemical binding]; other site
701347003691	Walker B motif; other site
701347003692	arginine finger; other site
701347003693	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
701347003694	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
701347003695	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003696	putative substrate translocation pore; other site
701347003697	lipoprotein; Provisional; Region: PRK10759
701347003698	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
701347003699	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
701347003700	domain interface [polypeptide binding]; other site
701347003701	putative active site [active]
701347003702	catalytic site [active]
701347003703	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
701347003704	domain interface [polypeptide binding]; other site
701347003705	putative active site [active]
701347003706	catalytic site [active]
701347003707	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
701347003708	CoA binding domain; Region: CoA_binding_2; pfam13380
701347003709	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
701347003710	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
701347003711	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
701347003712	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
701347003713	Uncharacterized conserved protein [Function unknown]; Region: COG3148
701347003714	thioredoxin 2; Provisional; Region: PRK10996
701347003715	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
701347003716	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
701347003717	catalytic residues [active]
701347003718	putative methyltransferase; Provisional; Region: PRK10864
701347003719	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
701347003720	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
701347003721	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
701347003722	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
701347003723	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
701347003724	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
701347003725	ligand binding site [chemical binding]; other site
701347003726	active site
701347003727	UGI interface [polypeptide binding]; other site
701347003728	catalytic site [active]
701347003729	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
701347003730	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
701347003731	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347003732	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347003733	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
701347003734	dimerization interface [polypeptide binding]; other site
701347003735	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
701347003736	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
701347003737	ATP binding site [chemical binding]; other site
701347003738	Mg++ binding site [ion binding]; other site
701347003739	motif III; other site
701347003740	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347003741	nucleotide binding region [chemical binding]; other site
701347003742	ATP-binding site [chemical binding]; other site
701347003743	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
701347003744	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347003745	S-adenosylmethionine binding site [chemical binding]; other site
701347003746	L-aspartate oxidase; Provisional; Region: PRK09077
701347003747	L-aspartate oxidase; Provisional; Region: PRK06175
701347003748	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
701347003749	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
701347003750	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
701347003751	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
701347003752	DNA binding residues [nucleotide binding]
701347003753	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
701347003754	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
701347003755	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
701347003756	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
701347003757	anti-sigma E factor; Provisional; Region: rseB; PRK09455
701347003758	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; cl01178
701347003759	GTP-binding protein LepA; Provisional; Region: PRK05433
701347003760	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
701347003761	G1 box; other site
701347003762	putative GEF interaction site [polypeptide binding]; other site
701347003763	GTP/Mg2+ binding site [chemical binding]; other site
701347003764	Switch I region; other site
701347003765	G2 box; other site
701347003766	G3 box; other site
701347003767	Switch II region; other site
701347003768	G4 box; other site
701347003769	G5 box; other site
701347003770	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
701347003771	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
701347003772	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
701347003773	signal peptidase I; Provisional; Region: PRK10861
701347003774	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
701347003775	Catalytic site [active]
701347003776	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
701347003777	ribonuclease III; Reviewed; Region: rnc; PRK00102
701347003778	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
701347003779	dimerization interface [polypeptide binding]; other site
701347003780	active site
701347003781	metal binding site [ion binding]; metal-binding site
701347003782	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
701347003783	dsRNA binding site [nucleotide binding]; other site
701347003784	GTPase Era; Reviewed; Region: era; PRK00089
701347003785	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
701347003786	G1 box; other site
701347003787	GTP/Mg2+ binding site [chemical binding]; other site
701347003788	Switch I region; other site
701347003789	G2 box; other site
701347003790	Switch II region; other site
701347003791	G3 box; other site
701347003792	G4 box; other site
701347003793	G5 box; other site
701347003794	KH domain; Region: KH_2; pfam07650
701347003795	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
701347003796	Recombination protein O N terminal; Region: RecO_N; pfam11967
701347003797	Recombination protein O C terminal; Region: RecO_C; pfam02565
701347003798	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
701347003799	active site
701347003800	hydrophilic channel; other site
701347003801	dimerization interface [polypeptide binding]; other site
701347003802	catalytic residues [active]
701347003803	active site lid [active]
701347003804	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
701347003805	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
701347003806	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347003807	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
701347003808	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347003809	putative active site [active]
701347003810	hypothetical protein; Provisional; Region: PRK11590
701347003811	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
701347003812	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
701347003813	nucleoside/Zn binding site; other site
701347003814	dimer interface [polypeptide binding]; other site
701347003815	catalytic motif [active]
701347003816	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
701347003817	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347003818	substrate binding pocket [chemical binding]; other site
701347003819	membrane-bound complex binding site; other site
701347003820	hinge residues; other site
701347003821	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347003822	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347003823	catalytic residue [active]
701347003824	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
701347003825	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
701347003826	dimerization interface [polypeptide binding]; other site
701347003827	ATP binding site [chemical binding]; other site
701347003828	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
701347003829	dimerization interface [polypeptide binding]; other site
701347003830	ATP binding site [chemical binding]; other site
701347003831	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
701347003832	putative active site [active]
701347003833	catalytic triad [active]
701347003834	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
701347003835	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347003836	dimer interface [polypeptide binding]; other site
701347003837	phosphorylation site [posttranslational modification]
701347003838	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347003839	ATP binding site [chemical binding]; other site
701347003840	Mg2+ binding site [ion binding]; other site
701347003841	G-X-G motif; other site
701347003842	hypothetical protein; Provisional; Region: PRK10722
701347003843	response regulator GlrR; Provisional; Region: PRK15115
701347003844	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347003845	active site
701347003846	phosphorylation site [posttranslational modification]
701347003847	intermolecular recognition site; other site
701347003848	dimerization interface [polypeptide binding]; other site
701347003849	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347003850	Walker A motif; other site
701347003851	ATP binding site [chemical binding]; other site
701347003852	Walker B motif; other site
701347003853	arginine finger; other site
701347003854	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
701347003855	Nitrogen regulatory protein P-II; Region: P-II; smart00938
701347003856	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
701347003857	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003858	putative substrate translocation pore; other site
701347003859	POT family; Region: PTR2; cl17359
701347003860	lysine decarboxylase CadA; Provisional; Region: PRK15400
701347003861	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
701347003862	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
701347003863	homodimer interface [polypeptide binding]; other site
701347003864	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347003865	catalytic residue [active]
701347003866	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
701347003867	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
701347003868	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
701347003869	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
701347003870	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347003871	DNA binding site [nucleotide binding]
701347003872	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
701347003873	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
701347003874	heme-binding site [chemical binding]; other site
701347003875	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
701347003876	FAD binding pocket [chemical binding]; other site
701347003877	FAD binding motif [chemical binding]; other site
701347003878	phosphate binding motif [ion binding]; other site
701347003879	beta-alpha-beta structure motif; other site
701347003880	NAD binding pocket [chemical binding]; other site
701347003881	Heme binding  pocket [chemical binding]; other site
701347003882	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
701347003883	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
701347003884	dimer interface [polypeptide binding]; other site
701347003885	active site
701347003886	glycine-pyridoxal phosphate binding site [chemical binding]; other site
701347003887	folate binding site [chemical binding]; other site
701347003888	Predicted membrane protein [Function unknown]; Region: COG2259
701347003889	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
701347003890	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
701347003891	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
701347003892	N- and C-terminal domain interface [polypeptide binding]; other site
701347003893	active site
701347003894	MgATP binding site [chemical binding]; other site
701347003895	catalytic site [active]
701347003896	metal binding site [ion binding]; metal-binding site
701347003897	carbohydrate binding site [chemical binding]; other site
701347003898	putative homodimer interface [polypeptide binding]; other site
701347003899	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347003900	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347003901	TM-ABC transporter signature motif; other site
701347003902	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347003903	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347003904	TM-ABC transporter signature motif; other site
701347003905	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347003906	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347003907	Walker A/P-loop; other site
701347003908	ATP binding site [chemical binding]; other site
701347003909	Q-loop/lid; other site
701347003910	ABC transporter signature motif; other site
701347003911	Walker B; other site
701347003912	D-loop; other site
701347003913	H-loop/switch region; other site
701347003914	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347003915	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
701347003916	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
701347003917	ligand binding site [chemical binding]; other site
701347003918	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
701347003919	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
701347003920	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
701347003921	nucleotide binding site [chemical binding]; other site
701347003922	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347003923	TPR motif; other site
701347003924	binding surface
701347003925	TPR repeat; Region: TPR_11; pfam13414
701347003926	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347003927	binding surface
701347003928	TPR motif; other site
701347003929	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
701347003930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003931	putative substrate translocation pore; other site
701347003932	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347003933	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
701347003934	active site
701347003935	catalytic residues [active]
701347003936	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
701347003937	MFS_1 like family; Region: MFS_1_like; pfam12832
701347003938	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
701347003939	PRD domain; Region: PRD; pfam00874
701347003940	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
701347003941	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
701347003942	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
701347003943	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
701347003944	active site
701347003945	dimerization interface [polypeptide binding]; other site
701347003946	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
701347003947	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
701347003948	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
701347003949	Rrf2 family protein; Region: rrf2_super; TIGR00738
701347003950	cysteine desulfurase; Provisional; Region: PRK14012
701347003951	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
701347003952	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347003953	catalytic residue [active]
701347003954	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
701347003955	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
701347003956	trimerization site [polypeptide binding]; other site
701347003957	active site
701347003958	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
701347003959	co-chaperone HscB; Provisional; Region: hscB; PRK05014
701347003960	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
701347003961	HSP70 interaction site [polypeptide binding]; other site
701347003962	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
701347003963	chaperone protein HscA; Provisional; Region: hscA; PRK05183
701347003964	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
701347003965	nucleotide binding site [chemical binding]; other site
701347003966	putative NEF/HSP70 interaction site [polypeptide binding]; other site
701347003967	SBD interface [polypeptide binding]; other site
701347003968	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
701347003969	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347003970	catalytic loop [active]
701347003971	iron binding site [ion binding]; other site
701347003972	hypothetical protein; Provisional; Region: PRK10721
701347003973	aminopeptidase B; Provisional; Region: PRK05015
701347003974	Peptidase; Region: DUF3663; pfam12404
701347003975	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
701347003976	interface (dimer of trimers) [polypeptide binding]; other site
701347003977	Substrate-binding/catalytic site; other site
701347003978	Zn-binding sites [ion binding]; other site
701347003979	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
701347003980	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
701347003981	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
701347003982	active site residue [active]
701347003983	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
701347003984	active site residue [active]
701347003985	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
701347003986	MG2 domain; Region: A2M_N; pfam01835
701347003987	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
701347003988	surface patch; other site
701347003989	thioester region; other site
701347003990	specificity defining residues; other site
701347003991	penicillin-binding protein 1C; Provisional; Region: PRK11240
701347003992	Transglycosylase; Region: Transgly; pfam00912
701347003993	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
701347003994	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
701347003995	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
701347003996	active site
701347003997	multimer interface [polypeptide binding]; other site
701347003998	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
701347003999	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347004000	FeS/SAM binding site; other site
701347004001	cytoskeletal protein RodZ; Provisional; Region: PRK10856
701347004002	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347004003	non-specific DNA binding site [nucleotide binding]; other site
701347004004	salt bridge; other site
701347004005	sequence-specific DNA binding site [nucleotide binding]; other site
701347004006	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
701347004007	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
701347004008	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
701347004009	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
701347004010	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
701347004011	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
701347004012	dimer interface [polypeptide binding]; other site
701347004013	motif 1; other site
701347004014	active site
701347004015	motif 2; other site
701347004016	motif 3; other site
701347004017	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
701347004018	anticodon binding site; other site
701347004019	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
701347004020	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
701347004021	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
701347004022	Trp docking motif [polypeptide binding]; other site
701347004023	GTP-binding protein Der; Reviewed; Region: PRK00093
701347004024	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
701347004025	G1 box; other site
701347004026	GTP/Mg2+ binding site [chemical binding]; other site
701347004027	Switch I region; other site
701347004028	G2 box; other site
701347004029	Switch II region; other site
701347004030	G3 box; other site
701347004031	G4 box; other site
701347004032	G5 box; other site
701347004033	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
701347004034	G1 box; other site
701347004035	GTP/Mg2+ binding site [chemical binding]; other site
701347004036	Switch I region; other site
701347004037	G2 box; other site
701347004038	G3 box; other site
701347004039	Switch II region; other site
701347004040	G4 box; other site
701347004041	G5 box; other site
701347004042	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
701347004043	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
701347004044	non-specific DNA interactions [nucleotide binding]; other site
701347004045	DNA binding site [nucleotide binding]
701347004046	sequence specific DNA binding site [nucleotide binding]; other site
701347004047	putative cAMP binding site [chemical binding]; other site
701347004048	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347004049	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347004050	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
701347004051	substrate binding site [chemical binding]; other site
701347004052	ATP binding site [chemical binding]; other site
701347004053	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
701347004054	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
701347004055	Class I aldolases; Region: Aldolase_Class_I; cl17187
701347004056	catalytic residue [active]
701347004057	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
701347004058	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
701347004059	NAD(P) binding site [chemical binding]; other site
701347004060	benzoate transport; Region: 2A0115; TIGR00895
701347004061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004062	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004063	shikimate transporter; Provisional; Region: PRK09952
701347004064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004065	putative substrate translocation pore; other site
701347004066	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
701347004067	active site
701347004068	catalytic residues [active]
701347004069	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004070	putative substrate translocation pore; other site
701347004071	POT family; Region: PTR2; cl17359
701347004072	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347004073	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347004074	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
701347004075	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
701347004076	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
701347004077	generic binding surface II; other site
701347004078	generic binding surface I; other site
701347004079	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
701347004080	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
701347004081	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
701347004082	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
701347004083	active site
701347004084	GMP synthase; Reviewed; Region: guaA; PRK00074
701347004085	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
701347004086	AMP/PPi binding site [chemical binding]; other site
701347004087	candidate oxyanion hole; other site
701347004088	catalytic triad [active]
701347004089	potential glutamine specificity residues [chemical binding]; other site
701347004090	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
701347004091	ATP Binding subdomain [chemical binding]; other site
701347004092	Ligand Binding sites [chemical binding]; other site
701347004093	Dimerization subdomain; other site
701347004094	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
701347004095	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347004096	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347004097	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347004098	putative active site [active]
701347004099	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
701347004100	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
701347004101	tetrameric interface [polypeptide binding]; other site
701347004102	NAD binding site [chemical binding]; other site
701347004103	catalytic residues [active]
701347004104	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
701347004105	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
701347004106	PYR/PP interface [polypeptide binding]; other site
701347004107	dimer interface [polypeptide binding]; other site
701347004108	TPP binding site [chemical binding]; other site
701347004109	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347004110	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
701347004111	TPP-binding site; other site
701347004112	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347004113	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347004114	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
701347004115	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
701347004116	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
701347004117	ligand binding site [chemical binding]; other site
701347004118	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347004119	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347004120	Walker A/P-loop; other site
701347004121	ATP binding site [chemical binding]; other site
701347004122	Q-loop/lid; other site
701347004123	ABC transporter signature motif; other site
701347004124	Walker B; other site
701347004125	D-loop; other site
701347004126	H-loop/switch region; other site
701347004127	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347004128	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347004129	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347004130	TM-ABC transporter signature motif; other site
701347004131	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347004132	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347004133	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347004134	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
701347004135	substrate binding site [chemical binding]; other site
701347004136	ATP binding site [chemical binding]; other site
701347004137	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
701347004138	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
701347004139	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
701347004140	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
701347004141	Cation transport protein; Region: TrkH; cl17365
701347004142	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
701347004143	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
701347004144	MASE1; Region: MASE1; pfam05231
701347004145	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347004146	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
701347004147	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347004148	exopolyphosphatase; Provisional; Region: PRK10854
701347004149	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347004150	nucleotide binding site [chemical binding]; other site
701347004151	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
701347004152	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
701347004153	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
701347004154	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
701347004155	domain interface [polypeptide binding]; other site
701347004156	active site
701347004157	catalytic site [active]
701347004158	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
701347004159	domain interface [polypeptide binding]; other site
701347004160	active site
701347004161	catalytic site [active]
701347004162	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
701347004163	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
701347004164	active site
701347004165	substrate binding site [chemical binding]; other site
701347004166	cosubstrate binding site; other site
701347004167	catalytic site [active]
701347004168	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
701347004169	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
701347004170	dimerization interface [polypeptide binding]; other site
701347004171	putative ATP binding site [chemical binding]; other site
701347004172	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
701347004173	beta-galactosidase; Region: BGL; TIGR03356
701347004174	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347004175	active site
701347004176	uracil transporter; Provisional; Region: PRK10720
701347004177	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
701347004178	DNA replication initiation factor; Provisional; Region: PRK08084
701347004179	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
701347004180	interface (dimer of trimers) [polypeptide binding]; other site
701347004181	Substrate-binding/catalytic site; other site
701347004182	Zn-binding sites [ion binding]; other site
701347004183	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
701347004184	active site
701347004185	dimer interface [polypeptide binding]; other site
701347004186	catalytic nucleophile [active]
701347004187	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
701347004188	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
701347004189	Helix-turn-helix; Region: HTH_3; pfam01381
701347004190	non-specific DNA binding site [nucleotide binding]; other site
701347004191	salt bridge; other site
701347004192	sequence-specific DNA binding site [nucleotide binding]; other site
701347004193	Winged helix-turn helix; Region: HTH_29; pfam13551
701347004194	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
701347004195	ArsC family; Region: ArsC; pfam03960
701347004196	catalytic residues [active]
701347004197	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
701347004198	Peptidase family M48; Region: Peptidase_M48; cl12018
701347004199	Domain of unknown function DUF20; Region: UPF0118; pfam01594
701347004200	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
701347004201	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
701347004202	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
701347004203	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
701347004204	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
701347004205	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
701347004206	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
701347004207	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
701347004208	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
701347004209	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
701347004210	catalytic triad [active]
701347004211	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
701347004212	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
701347004213	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
701347004214	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
701347004215	dihydrodipicolinate synthase; Region: dapA; TIGR00674
701347004216	dimer interface [polypeptide binding]; other site
701347004217	active site
701347004218	catalytic residue [active]
701347004219	lipoprotein; Provisional; Region: PRK11679
701347004220	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
701347004221	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
701347004222	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
701347004223	ATP binding site [chemical binding]; other site
701347004224	active site
701347004225	substrate binding site [chemical binding]; other site
701347004226	Predicted metalloprotease [General function prediction only]; Region: COG2321
701347004227	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
701347004228	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
701347004229	Helicase; Region: Helicase_RecD; pfam05127
701347004230	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
701347004231	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
701347004232	putative hydrolase; Provisional; Region: PRK11460
701347004233	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
701347004234	hypothetical protein; Provisional; Region: PRK13664
701347004235	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
701347004236	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
701347004237	metal binding site [ion binding]; metal-binding site
701347004238	dimer interface [polypeptide binding]; other site
701347004239	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
701347004240	ArsC family; Region: ArsC; pfam03960
701347004241	putative catalytic residues [active]
701347004242	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
701347004243	Protein export membrane protein; Region: SecD_SecF; cl14618
701347004244	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
701347004245	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
701347004246	dimer interface [polypeptide binding]; other site
701347004247	ADP-ribose binding site [chemical binding]; other site
701347004248	active site
701347004249	nudix motif; other site
701347004250	metal binding site [ion binding]; metal-binding site
701347004251	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
701347004252	transketolase; Reviewed; Region: PRK12753
701347004253	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
701347004254	TPP-binding site [chemical binding]; other site
701347004255	dimer interface [polypeptide binding]; other site
701347004256	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
701347004257	PYR/PP interface [polypeptide binding]; other site
701347004258	dimer interface [polypeptide binding]; other site
701347004259	TPP binding site [chemical binding]; other site
701347004260	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
701347004261	transaldolase-like protein; Provisional; Region: PTZ00411
701347004262	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
701347004263	active site
701347004264	dimer interface [polypeptide binding]; other site
701347004265	catalytic residue [active]
701347004266	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
701347004267	Malic enzyme, N-terminal domain; Region: malic; pfam00390
701347004268	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
701347004269	putative NAD(P) binding site [chemical binding]; other site
701347004270	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
701347004271	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
701347004272	putative hexamer interface [polypeptide binding]; other site
701347004273	putative hexagonal pore; other site
701347004274	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
701347004275	G1 box; other site
701347004276	GTP/Mg2+ binding site [chemical binding]; other site
701347004277	G2 box; other site
701347004278	Switch I region; other site
701347004279	G3 box; other site
701347004280	Switch II region; other site
701347004281	G4 box; other site
701347004282	G5 box; other site
701347004283	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
701347004284	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
701347004285	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
701347004286	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
701347004287	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
701347004288	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
701347004289	Hexamer interface [polypeptide binding]; other site
701347004290	Hexagonal pore residue; other site
701347004291	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
701347004292	Hexamer/Pentamer interface [polypeptide binding]; other site
701347004293	central pore; other site
701347004294	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
701347004295	putative catalytic cysteine [active]
701347004296	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
701347004297	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
701347004298	active site
701347004299	metal binding site [ion binding]; metal-binding site
701347004300	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
701347004301	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
701347004302	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
701347004303	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
701347004304	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
701347004305	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
701347004306	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
701347004307	putative hexamer interface [polypeptide binding]; other site
701347004308	putative hexagonal pore; other site
701347004309	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
701347004310	putative hexamer interface [polypeptide binding]; other site
701347004311	putative hexagonal pore; other site
701347004312	carboxysome structural protein EutK; Provisional; Region: PRK15466
701347004313	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
701347004314	Hexamer interface [polypeptide binding]; other site
701347004315	Hexagonal pore residue; other site
701347004316	transcriptional regulator EutR; Provisional; Region: PRK10130
701347004317	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347004318	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347004319	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
701347004320	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
701347004321	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
701347004322	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
701347004323	active site
701347004324	metal binding site [ion binding]; metal-binding site
701347004325	putative acetyltransferase; Provisional; Region: PRK03624
701347004326	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347004327	Coenzyme A binding pocket [chemical binding]; other site
701347004328	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
701347004329	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
701347004330	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
701347004331	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
701347004332	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
701347004333	nudix motif; other site
701347004334	thiosulfate transporter subunit; Provisional; Region: PRK10852
701347004335	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
701347004336	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
701347004337	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347004338	dimer interface [polypeptide binding]; other site
701347004339	conserved gate region; other site
701347004340	putative PBP binding loops; other site
701347004341	ABC-ATPase subunit interface; other site
701347004342	sulfate transport protein; Provisional; Region: cysT; CHL00187
701347004343	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347004344	dimer interface [polypeptide binding]; other site
701347004345	conserved gate region; other site
701347004346	putative PBP binding loops; other site
701347004347	ABC-ATPase subunit interface; other site
701347004348	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
701347004349	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
701347004350	Walker A/P-loop; other site
701347004351	ATP binding site [chemical binding]; other site
701347004352	Q-loop/lid; other site
701347004353	ABC transporter signature motif; other site
701347004354	Walker B; other site
701347004355	D-loop; other site
701347004356	H-loop/switch region; other site
701347004357	TOBE-like domain; Region: TOBE_3; pfam12857
701347004358	cysteine synthase B; Region: cysM; TIGR01138
701347004359	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
701347004360	dimer interface [polypeptide binding]; other site
701347004361	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347004362	catalytic residue [active]
701347004363	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
701347004364	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
701347004365	catalytic triad [active]
701347004366	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
701347004367	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347004368	DNA-binding site [nucleotide binding]; DNA binding site
701347004369	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347004370	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347004371	homodimer interface [polypeptide binding]; other site
701347004372	catalytic residue [active]
701347004373	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
701347004374	dimer interface [polypeptide binding]; other site
701347004375	pyridoxamine kinase; Validated; Region: PRK05756
701347004376	pyridoxal binding site [chemical binding]; other site
701347004377	ATP binding site [chemical binding]; other site
701347004378	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
701347004379	HPr interaction site; other site
701347004380	glycerol kinase (GK) interaction site [polypeptide binding]; other site
701347004381	active site
701347004382	phosphorylation site [posttranslational modification]
701347004383	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
701347004384	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
701347004385	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
701347004386	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
701347004387	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347004388	dimerization domain swap beta strand [polypeptide binding]; other site
701347004389	regulatory protein interface [polypeptide binding]; other site
701347004390	active site
701347004391	regulatory phosphorylation site [posttranslational modification]; other site
701347004392	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
701347004393	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
701347004394	dimer interface [polypeptide binding]; other site
701347004395	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347004396	catalytic residue [active]
701347004397	putative sulfate transport protein CysZ; Validated; Region: PRK04949
701347004398	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
701347004399	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
701347004400	FtsZ protein binding site [polypeptide binding]; other site
701347004401	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
701347004402	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
701347004403	nucleotide binding pocket [chemical binding]; other site
701347004404	K-X-D-G motif; other site
701347004405	catalytic site [active]
701347004406	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
701347004407	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
701347004408	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
701347004409	Dimer interface [polypeptide binding]; other site
701347004410	BRCT sequence motif; other site
701347004411	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
701347004412	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
701347004413	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
701347004414	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347004415	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347004416	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
701347004417	putative dimerization interface [polypeptide binding]; other site
701347004418	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
701347004419	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
701347004420	active site
701347004421	HIGH motif; other site
701347004422	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
701347004423	active site
701347004424	KMSKS motif; other site
701347004425	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
701347004426	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
701347004427	MASE1; Region: MASE1; pfam05231
701347004428	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347004429	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
701347004430	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347004431	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
701347004432	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
701347004433	Nucleoside recognition; Region: Gate; pfam07670
701347004434	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
701347004435	manganese transport protein MntH; Reviewed; Region: PRK00701
701347004436	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
701347004437	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
701347004438	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
701347004439	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
701347004440	dimer interface [polypeptide binding]; other site
701347004441	PYR/PP interface [polypeptide binding]; other site
701347004442	TPP binding site [chemical binding]; other site
701347004443	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347004444	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
701347004445	TPP-binding site [chemical binding]; other site
701347004446	dimer interface [polypeptide binding]; other site
701347004447	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
701347004448	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
701347004449	Cl- selectivity filter; other site
701347004450	Cl- binding residues [ion binding]; other site
701347004451	pore gating glutamate residue; other site
701347004452	dimer interface [polypeptide binding]; other site
701347004453	glucokinase; Provisional; Region: glk; PRK00292
701347004454	glucokinase, proteobacterial type; Region: glk; TIGR00749
701347004455	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
701347004456	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347004457	active site
701347004458	phosphorylation site [posttranslational modification]
701347004459	intermolecular recognition site; other site
701347004460	dimerization interface [polypeptide binding]; other site
701347004461	LytTr DNA-binding domain; Region: LytTR; pfam04397
701347004462	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
701347004463	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
701347004464	GAF domain; Region: GAF; pfam01590
701347004465	Histidine kinase; Region: His_kinase; pfam06580
701347004466	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347004467	ATP binding site [chemical binding]; other site
701347004468	Mg2+ binding site [ion binding]; other site
701347004469	G-X-G motif; other site
701347004470	aminotransferase; Validated; Region: PRK08175
701347004471	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347004472	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347004473	homodimer interface [polypeptide binding]; other site
701347004474	catalytic residue [active]
701347004475	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
701347004476	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
701347004477	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
701347004478	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347004479	substrate binding pocket [chemical binding]; other site
701347004480	membrane-bound complex binding site; other site
701347004481	hinge residues; other site
701347004482	Transposase; Region: HTH_Tnp_1; pfam01527
701347004483	HTH-like domain; Region: HTH_21; pfam13276
701347004484	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
701347004485	Integrase core domain; Region: rve; pfam00665
701347004486	Integrase core domain; Region: rve_3; pfam13683
701347004487	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347004488	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347004489	metal binding site [ion binding]; metal-binding site
701347004490	active site
701347004491	I-site; other site
701347004492	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
701347004493	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347004494	Serine hydrolase; Region: Ser_hydrolase; pfam06821
701347004495	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
701347004496	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187
701347004497	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
701347004498	acyl-activating enzyme (AAE) consensus motif; other site
701347004499	AMP binding site [chemical binding]; other site
701347004500	active site
701347004501	CoA binding site [chemical binding]; other site
701347004502	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
701347004503	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
701347004504	NADP binding site [chemical binding]; other site
701347004505	dimer interface [polypeptide binding]; other site
701347004506	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
701347004507	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
701347004508	substrate binding pocket [chemical binding]; other site
701347004509	active site
701347004510	iron coordination sites [ion binding]; other site
701347004511	Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853
701347004512	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004513	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347004514	putative substrate translocation pore; other site
701347004515	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
701347004516	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
701347004517	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
701347004518	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
701347004519	acyl-activating enzyme (AAE) consensus motif; other site
701347004520	AMP binding site [chemical binding]; other site
701347004521	active site
701347004522	CoA binding site [chemical binding]; other site
701347004523	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
701347004524	2-methylcitrate dehydratase; Region: prpD; TIGR02330
701347004525	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
701347004526	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
701347004527	dimer interface [polypeptide binding]; other site
701347004528	active site
701347004529	citrylCoA binding site [chemical binding]; other site
701347004530	oxalacetate/citrate binding site [chemical binding]; other site
701347004531	coenzyme A binding site [chemical binding]; other site
701347004532	catalytic triad [active]
701347004533	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
701347004534	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
701347004535	tetramer interface [polypeptide binding]; other site
701347004536	active site
701347004537	Mg2+/Mn2+ binding site [ion binding]; other site
701347004538	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
701347004539	Propionate catabolism activator; Region: PrpR_N; pfam06506
701347004540	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347004541	Walker A motif; other site
701347004542	ATP binding site [chemical binding]; other site
701347004543	Walker B motif; other site
701347004544	arginine finger; other site
701347004545	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347004546	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347004547	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347004548	metal binding site [ion binding]; metal-binding site
701347004549	active site
701347004550	I-site; other site
701347004551	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
701347004552	Transposase; Region: HTH_Tnp_1; pfam01527
701347004553	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
701347004554	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
701347004555	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
701347004556	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
701347004557	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
701347004558	dimer interface [polypeptide binding]; other site
701347004559	active site
701347004560	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
701347004561	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347004562	substrate binding site [chemical binding]; other site
701347004563	oxyanion hole (OAH) forming residues; other site
701347004564	trimer interface [polypeptide binding]; other site
701347004565	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
701347004566	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
701347004567	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
701347004568	catalytic core [active]
701347004569	hypothetical protein; Provisional; Region: PRK04946
701347004570	Smr domain; Region: Smr; pfam01713
701347004571	HemK family putative methylases; Region: hemK_fam; TIGR00536
701347004572	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347004573	S-adenosylmethionine binding site [chemical binding]; other site
701347004574	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
701347004575	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
701347004576	Tetramer interface [polypeptide binding]; other site
701347004577	active site
701347004578	FMN-binding site [chemical binding]; other site
701347004579	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
701347004580	hypothetical protein; Provisional; Region: PRK10621
701347004581	Predicted permeases [General function prediction only]; Region: COG0730
701347004582	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
701347004583	YfcL protein; Region: YfcL; pfam08891
701347004584	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
701347004585	Uncharacterized conserved protein [Function unknown]; Region: COG4121
701347004586	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
701347004587	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
701347004588	dimer interface [polypeptide binding]; other site
701347004589	active site
701347004590	putative transporter; Provisional; Region: PRK12382
701347004591	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004592	putative substrate translocation pore; other site
701347004593	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
701347004594	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
701347004595	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
701347004596	ligand binding site [chemical binding]; other site
701347004597	NAD binding site [chemical binding]; other site
701347004598	catalytic site [active]
701347004599	homodimer interface [polypeptide binding]; other site
701347004600	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
701347004601	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
701347004602	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
701347004603	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
701347004604	dimerization interface 3.5A [polypeptide binding]; other site
701347004605	active site
701347004606	hypothetical protein; Provisional; Region: PRK10847
701347004607	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
701347004608	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
701347004609	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
701347004610	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
701347004611	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
701347004612	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
701347004613	cell division protein DedD; Provisional; Region: PRK11633
701347004614	Sporulation related domain; Region: SPOR; pfam05036
701347004615	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
701347004616	colicin V production protein; Provisional; Region: PRK10845
701347004617	amidophosphoribosyltransferase; Provisional; Region: PRK09246
701347004618	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
701347004619	active site
701347004620	tetramer interface [polypeptide binding]; other site
701347004621	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347004622	active site
701347004623	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
701347004624	Flavoprotein; Region: Flavoprotein; pfam02441
701347004625	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
701347004626	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347004627	substrate binding pocket [chemical binding]; other site
701347004628	membrane-bound complex binding site; other site
701347004629	hinge residues; other site
701347004630	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
701347004631	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347004632	substrate binding pocket [chemical binding]; other site
701347004633	membrane-bound complex binding site; other site
701347004634	hinge residues; other site
701347004635	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347004636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347004637	dimer interface [polypeptide binding]; other site
701347004638	conserved gate region; other site
701347004639	putative PBP binding loops; other site
701347004640	ABC-ATPase subunit interface; other site
701347004641	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347004642	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347004643	dimer interface [polypeptide binding]; other site
701347004644	conserved gate region; other site
701347004645	putative PBP binding loops; other site
701347004646	ABC-ATPase subunit interface; other site
701347004647	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
701347004648	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347004649	Walker A/P-loop; other site
701347004650	ATP binding site [chemical binding]; other site
701347004651	Q-loop/lid; other site
701347004652	ABC transporter signature motif; other site
701347004653	Walker B; other site
701347004654	D-loop; other site
701347004655	H-loop/switch region; other site
701347004656	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
701347004657	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
701347004658	putative NAD(P) binding site [chemical binding]; other site
701347004659	putative active site [active]
701347004660	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
701347004661	homooctamer interface [polypeptide binding]; other site
701347004662	active site
701347004663	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
701347004664	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
701347004665	C-terminal domain interface [polypeptide binding]; other site
701347004666	GSH binding site (G-site) [chemical binding]; other site
701347004667	dimer interface [polypeptide binding]; other site
701347004668	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
701347004669	N-terminal domain interface [polypeptide binding]; other site
701347004670	putative dimer interface [polypeptide binding]; other site
701347004671	active site
701347004672	glutathione S-transferase; Provisional; Region: PRK15113
701347004673	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
701347004674	C-terminal domain interface [polypeptide binding]; other site
701347004675	GSH binding site (G-site) [chemical binding]; other site
701347004676	dimer interface [polypeptide binding]; other site
701347004677	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
701347004678	N-terminal domain interface [polypeptide binding]; other site
701347004679	putative dimer interface [polypeptide binding]; other site
701347004680	putative substrate binding pocket (H-site) [chemical binding]; other site
701347004681	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
701347004682	active site
701347004683	metal binding site [ion binding]; metal-binding site
701347004684	homotetramer interface [polypeptide binding]; other site
701347004685	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
701347004686	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
701347004687	nudix motif; other site
701347004688	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347004689	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347004690	DNA binding site [nucleotide binding]
701347004691	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
701347004692	putative dimerization interface [polypeptide binding]; other site
701347004693	putative ligand binding site [chemical binding]; other site
701347004694	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347004695	active site
701347004696	phosphorylation site [posttranslational modification]
701347004697	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
701347004698	active site
701347004699	P-loop; other site
701347004700	phosphorylation site [posttranslational modification]
701347004701	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
701347004702	transketolase; Reviewed; Region: PRK05899
701347004703	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
701347004704	TPP-binding site [chemical binding]; other site
701347004705	dimer interface [polypeptide binding]; other site
701347004706	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
701347004707	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
701347004708	PYR/PP interface [polypeptide binding]; other site
701347004709	dimer interface [polypeptide binding]; other site
701347004710	TPP binding site [chemical binding]; other site
701347004711	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
701347004712	phosphate acetyltransferase; Reviewed; Region: PRK05632
701347004713	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
701347004714	DRTGG domain; Region: DRTGG; pfam07085
701347004715	phosphate acetyltransferase; Region: pta; TIGR00651
701347004716	propionate/acetate kinase; Provisional; Region: PRK12379
701347004717	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
701347004718	hypothetical protein; Provisional; Region: PRK01816
701347004719	hypothetical protein; Validated; Region: PRK05445
701347004720	putative phosphatase; Provisional; Region: PRK11587
701347004721	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347004722	active site
701347004723	motif I; other site
701347004724	motif II; other site
701347004725	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
701347004726	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
701347004727	TrkA-C domain; Region: TrkA_C; pfam02080
701347004728	TrkA-C domain; Region: TrkA_C; pfam02080
701347004729	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
701347004730	5'-nucleotidase; Provisional; Region: PRK03826
701347004731	aminotransferase AlaT; Validated; Region: PRK09265
701347004732	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347004733	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347004734	homodimer interface [polypeptide binding]; other site
701347004735	catalytic residue [active]
701347004736	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
701347004737	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347004738	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
701347004739	putative dimerization interface [polypeptide binding]; other site
701347004740	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
701347004741	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
701347004742	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
701347004743	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
701347004744	NADH dehydrogenase subunit D; Validated; Region: PRK06075
701347004745	NADH dehydrogenase subunit E; Validated; Region: PRK07539
701347004746	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
701347004747	putative dimer interface [polypeptide binding]; other site
701347004748	[2Fe-2S] cluster binding site [ion binding]; other site
701347004749	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
701347004750	SLBB domain; Region: SLBB; pfam10531
701347004751	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
701347004752	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
701347004753	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347004754	catalytic loop [active]
701347004755	iron binding site [ion binding]; other site
701347004756	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
701347004757	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
701347004758	[4Fe-4S] binding site [ion binding]; other site
701347004759	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
701347004760	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
701347004761	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
701347004762	4Fe-4S binding domain; Region: Fer4; pfam00037
701347004763	4Fe-4S binding domain; Region: Fer4; pfam00037
701347004764	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
701347004765	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
701347004766	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
701347004767	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
701347004768	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
701347004769	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
701347004770	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
701347004771	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
701347004772	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
701347004773	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
701347004774	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
701347004775	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
701347004776	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347004777	active site
701347004778	phosphorylation site [posttranslational modification]
701347004779	intermolecular recognition site; other site
701347004780	dimerization interface [polypeptide binding]; other site
701347004781	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
701347004782	putative acyltransferase; Provisional; Region: PRK10314
701347004783	Coenzyme A binding pocket [chemical binding]; other site
701347004784	hypothetical protein; Provisional; Region: PRK10404
701347004785	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
701347004786	chorismate binding enzyme; Region: Chorismate_bind; cl10555
701347004787	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
701347004788	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
701347004789	dimer interface [polypeptide binding]; other site
701347004790	tetramer interface [polypeptide binding]; other site
701347004791	PYR/PP interface [polypeptide binding]; other site
701347004792	TPP binding site [chemical binding]; other site
701347004793	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
701347004794	TPP-binding site; other site
701347004795	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
701347004796	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347004797	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
701347004798	substrate binding site [chemical binding]; other site
701347004799	oxyanion hole (OAH) forming residues; other site
701347004800	trimer interface [polypeptide binding]; other site
701347004801	O-succinylbenzoate synthase; Provisional; Region: PRK05105
701347004802	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
701347004803	active site
701347004804	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
701347004805	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
701347004806	acyl-activating enzyme (AAE) consensus motif; other site
701347004807	putative AMP binding site [chemical binding]; other site
701347004808	putative active site [active]
701347004809	putative CoA binding site [chemical binding]; other site
701347004810	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
701347004811	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
701347004812	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
701347004813	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
701347004814	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347004815	active site
701347004816	phosphorylation site [posttranslational modification]
701347004817	intermolecular recognition site; other site
701347004818	dimerization interface [polypeptide binding]; other site
701347004819	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347004820	DNA binding site [nucleotide binding]
701347004821	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
701347004822	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
701347004823	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
701347004824	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347004825	dimer interface [polypeptide binding]; other site
701347004826	phosphorylation site [posttranslational modification]
701347004827	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347004828	ATP binding site [chemical binding]; other site
701347004829	Mg2+ binding site [ion binding]; other site
701347004830	G-X-G motif; other site
701347004831	YfaZ precursor; Region: YfaZ; pfam07437
701347004832	hypothetical protein; Provisional; Region: PRK03673
701347004833	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
701347004834	putative MPT binding site; other site
701347004835	Competence-damaged protein; Region: CinA; cl00666
701347004836	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
701347004837	Transcriptional regulator [Transcription]; Region: IclR; COG1414
701347004838	Bacterial transcriptional regulator; Region: IclR; pfam01614
701347004839	L-rhamnonate dehydratase; Provisional; Region: PRK15440
701347004840	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
701347004841	putative active site pocket [active]
701347004842	putative metal binding site [ion binding]; other site
701347004843	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
701347004844	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004845	putative substrate translocation pore; other site
701347004846	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
701347004847	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
701347004848	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347004849	Cysteine-rich domain; Region: CCG; pfam02754
701347004850	Cysteine-rich domain; Region: CCG; pfam02754
701347004851	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
701347004852	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
701347004853	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
701347004854	hydroxyglutarate oxidase; Provisional; Region: PRK11728
701347004855	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
701347004856	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
701347004857	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004858	putative substrate translocation pore; other site
701347004859	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
701347004860	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
701347004861	active site
701347004862	catalytic site [active]
701347004863	metal binding site [ion binding]; metal-binding site
701347004864	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347004865	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347004866	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
701347004867	dimerization interface [polypeptide binding]; other site
701347004868	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347004869	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347004870	putative substrate translocation pore; other site
701347004871	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
701347004872	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347004873	catalytic loop [active]
701347004874	iron binding site [ion binding]; other site
701347004875	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
701347004876	dimer interface [polypeptide binding]; other site
701347004877	putative radical transfer pathway; other site
701347004878	diiron center [ion binding]; other site
701347004879	tyrosyl radical; other site
701347004880	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
701347004881	ATP cone domain; Region: ATP-cone; pfam03477
701347004882	Class I ribonucleotide reductase; Region: RNR_I; cd01679
701347004883	active site
701347004884	dimer interface [polypeptide binding]; other site
701347004885	catalytic residues [active]
701347004886	effector binding site; other site
701347004887	R2 peptide binding site; other site
701347004888	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
701347004889	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347004890	S-adenosylmethionine binding site [chemical binding]; other site
701347004891	DNA gyrase subunit A; Validated; Region: PRK05560
701347004892	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
701347004893	CAP-like domain; other site
701347004894	active site
701347004895	primary dimer interface [polypeptide binding]; other site
701347004896	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
701347004897	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
701347004898	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
701347004899	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
701347004900	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
701347004901	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
701347004902	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
701347004903	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
701347004904	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
701347004905	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
701347004906	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
701347004907	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347004908	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347004909	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347004910	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347004911	putative acyltransferase; Provisional; Region: PRK05790
701347004912	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
701347004913	dimer interface [polypeptide binding]; other site
701347004914	active site
701347004915	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
701347004916	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
701347004917	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
701347004918	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
701347004919	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347004920	active site
701347004921	phosphorylation site [posttranslational modification]
701347004922	intermolecular recognition site; other site
701347004923	dimerization interface [polypeptide binding]; other site
701347004924	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347004925	Walker A motif; other site
701347004926	ATP binding site [chemical binding]; other site
701347004927	Walker B motif; other site
701347004928	arginine finger; other site
701347004929	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347004930	sensory histidine kinase AtoS; Provisional; Region: PRK11360
701347004931	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347004932	putative active site [active]
701347004933	heme pocket [chemical binding]; other site
701347004934	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347004935	dimer interface [polypeptide binding]; other site
701347004936	phosphorylation site [posttranslational modification]
701347004937	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347004938	ATP binding site [chemical binding]; other site
701347004939	Mg2+ binding site [ion binding]; other site
701347004940	G-X-G motif; other site
701347004941	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
701347004942	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347004943	dimer interface [polypeptide binding]; other site
701347004944	phosphorylation site [posttranslational modification]
701347004945	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347004946	ATP binding site [chemical binding]; other site
701347004947	Mg2+ binding site [ion binding]; other site
701347004948	G-X-G motif; other site
701347004949	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
701347004950	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347004951	active site
701347004952	phosphorylation site [posttranslational modification]
701347004953	intermolecular recognition site; other site
701347004954	dimerization interface [polypeptide binding]; other site
701347004955	transcriptional regulator RcsB; Provisional; Region: PRK10840
701347004956	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347004957	active site
701347004958	phosphorylation site [posttranslational modification]
701347004959	intermolecular recognition site; other site
701347004960	dimerization interface [polypeptide binding]; other site
701347004961	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347004962	DNA binding residues [nucleotide binding]
701347004963	dimerization interface [polypeptide binding]; other site
701347004964	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
701347004965	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347004966	ATP binding site [chemical binding]; other site
701347004967	Mg2+ binding site [ion binding]; other site
701347004968	G-X-G motif; other site
701347004969	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
701347004970	putative binding surface; other site
701347004971	active site
701347004972	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347004973	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347004974	trimer interface [polypeptide binding]; other site
701347004975	eyelet of channel; other site
701347004976	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
701347004977	ApbE family; Region: ApbE; pfam02424
701347004978	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
701347004979	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
701347004980	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347004981	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
701347004982	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
701347004983	DNA binding site [nucleotide binding]
701347004984	active site
701347004985	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
701347004986	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
701347004987	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
701347004988	Walker A/P-loop; other site
701347004989	ATP binding site [chemical binding]; other site
701347004990	Q-loop/lid; other site
701347004991	ABC transporter signature motif; other site
701347004992	Walker B; other site
701347004993	D-loop; other site
701347004994	H-loop/switch region; other site
701347004995	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
701347004996	MgtE intracellular N domain; Region: MgtE_N; smart00924
701347004997	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
701347004998	Divalent cation transporter; Region: MgtE; cl00786
701347004999	malate:quinone oxidoreductase; Validated; Region: PRK05257
701347005000	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
701347005001	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
701347005002	secondary substrate binding site; other site
701347005003	primary substrate binding site; other site
701347005004	inhibition loop; other site
701347005005	dimerization interface [polypeptide binding]; other site
701347005006	YadA-like C-terminal region; Region: YadA; pfam03895
701347005007	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
701347005008	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
701347005009	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
701347005010	Sulfatase; Region: Sulfatase; pfam00884
701347005011	hypothetical protein; Provisional; Region: PRK13689
701347005012	Nucleoid-associated protein [General function prediction only]; Region: COG3081
701347005013	nucleoid-associated protein NdpA; Validated; Region: PRK00378
701347005014	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
701347005015	5S rRNA interface [nucleotide binding]; other site
701347005016	CTC domain interface [polypeptide binding]; other site
701347005017	L16 interface [polypeptide binding]; other site
701347005018	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
701347005019	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347005020	ATP binding site [chemical binding]; other site
701347005021	putative Mg++ binding site [ion binding]; other site
701347005022	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347005023	nucleotide binding region [chemical binding]; other site
701347005024	ATP-binding site [chemical binding]; other site
701347005025	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
701347005026	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
701347005027	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347005028	RNA binding surface [nucleotide binding]; other site
701347005029	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
701347005030	active site
701347005031	uracil binding [chemical binding]; other site
701347005032	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347005033	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
701347005034	putative substrate translocation pore; other site
701347005035	hypothetical protein; Provisional; Region: PRK11835
701347005036	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
701347005037	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347005038	Walker A/P-loop; other site
701347005039	ATP binding site [chemical binding]; other site
701347005040	Q-loop/lid; other site
701347005041	ABC transporter signature motif; other site
701347005042	Walker B; other site
701347005043	D-loop; other site
701347005044	H-loop/switch region; other site
701347005045	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
701347005046	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347005047	Walker A/P-loop; other site
701347005048	ATP binding site [chemical binding]; other site
701347005049	Q-loop/lid; other site
701347005050	ABC transporter signature motif; other site
701347005051	Walker B; other site
701347005052	D-loop; other site
701347005053	H-loop/switch region; other site
701347005054	microcin C ABC transporter permease; Provisional; Region: PRK15021
701347005055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347005056	dimer interface [polypeptide binding]; other site
701347005057	conserved gate region; other site
701347005058	ABC-ATPase subunit interface; other site
701347005059	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
701347005060	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347005061	dimer interface [polypeptide binding]; other site
701347005062	conserved gate region; other site
701347005063	putative PBP binding loops; other site
701347005064	ABC-ATPase subunit interface; other site
701347005065	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
701347005066	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
701347005067	phage resistance protein; Provisional; Region: PRK10551
701347005068	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
701347005069	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347005070	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
701347005071	NlpC/P60 family; Region: NLPC_P60; pfam00877
701347005072	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
701347005073	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
701347005074	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
701347005075	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
701347005076	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
701347005077	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
701347005078	mannonate dehydratase; Provisional; Region: PRK03906
701347005079	mannonate dehydratase; Region: uxuA; TIGR00695
701347005080	elongation factor P; Provisional; Region: PRK04542
701347005081	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
701347005082	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
701347005083	RNA binding site [nucleotide binding]; other site
701347005084	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
701347005085	RNA binding site [nucleotide binding]; other site
701347005086	Flagellin N-methylase; Region: FliB; cl00497
701347005087	sugar efflux transporter B; Provisional; Region: PRK15011
701347005088	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347005089	putative substrate translocation pore; other site
701347005090	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
701347005091	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347005092	active site
701347005093	phosphorylation site [posttranslational modification]
701347005094	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347005095	dimerization domain swap beta strand [polypeptide binding]; other site
701347005096	regulatory protein interface [polypeptide binding]; other site
701347005097	active site
701347005098	regulatory phosphorylation site [posttranslational modification]; other site
701347005099	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
701347005100	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
701347005101	putative substrate binding site [chemical binding]; other site
701347005102	putative ATP binding site [chemical binding]; other site
701347005103	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
701347005104	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
701347005105	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
701347005106	active site
701347005107	P-loop; other site
701347005108	phosphorylation site [posttranslational modification]
701347005109	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
701347005110	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
701347005111	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347005112	substrate binding site [chemical binding]; other site
701347005113	ATP binding site [chemical binding]; other site
701347005114	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
701347005115	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
701347005116	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
701347005117	Nucleoside recognition; Region: Gate; pfam07670
701347005118	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
701347005119	putative kinase; Provisional; Region: PRK09954
701347005120	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
701347005121	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
701347005122	substrate binding site [chemical binding]; other site
701347005123	ATP binding site [chemical binding]; other site
701347005124	endonuclease IV; Provisional; Region: PRK01060
701347005125	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
701347005126	AP (apurinic/apyrimidinic) site pocket; other site
701347005127	DNA interaction; other site
701347005128	Metal-binding active site; metal-binding site
701347005129	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
701347005130	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
701347005131	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347005132	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
701347005133	putative dimerization interface [polypeptide binding]; other site
701347005134	lysine transporter; Provisional; Region: PRK10836
701347005135	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
701347005136	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347005137	N-terminal plug; other site
701347005138	ligand-binding site [chemical binding]; other site
701347005139	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
701347005140	S-formylglutathione hydrolase; Region: PLN02442
701347005141	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347005142	putative substrate translocation pore; other site
701347005143	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
701347005144	homodecamer interface [polypeptide binding]; other site
701347005145	GTP cyclohydrolase I; Provisional; Region: PLN03044
701347005146	active site
701347005147	putative catalytic site residues [active]
701347005148	zinc binding site [ion binding]; other site
701347005149	GTP-CH-I/GFRP interaction surface; other site
701347005150	Predicted membrane protein [Function unknown]; Region: COG2311
701347005151	hypothetical protein; Provisional; Region: PRK10835
701347005152	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
701347005153	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347005154	DNA binding site [nucleotide binding]
701347005155	domain linker motif; other site
701347005156	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
701347005157	dimerization interface (closed form) [polypeptide binding]; other site
701347005158	ligand binding site [chemical binding]; other site
701347005159	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
701347005160	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
701347005161	ligand binding site [chemical binding]; other site
701347005162	calcium binding site [ion binding]; other site
701347005163	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347005164	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
701347005165	Walker A/P-loop; other site
701347005166	ATP binding site [chemical binding]; other site
701347005167	Q-loop/lid; other site
701347005168	ABC transporter signature motif; other site
701347005169	Walker B; other site
701347005170	D-loop; other site
701347005171	H-loop/switch region; other site
701347005172	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347005173	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347005174	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347005175	TM-ABC transporter signature motif; other site
701347005176	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
701347005177	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
701347005178	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
701347005179	homodimer interface [polypeptide binding]; other site
701347005180	active site
701347005181	FMN binding site [chemical binding]; other site
701347005182	substrate binding site [chemical binding]; other site
701347005183	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
701347005184	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
701347005185	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347005186	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
701347005187	putative active site [active]
701347005188	cytidine deaminase; Provisional; Region: PRK09027
701347005189	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
701347005190	active site
701347005191	catalytic motif [active]
701347005192	Zn binding site [ion binding]; other site
701347005193	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
701347005194	active site
701347005195	catalytic motif [active]
701347005196	Zn binding site [ion binding]; other site
701347005197	hypothetical protein; Provisional; Region: PRK10711
701347005198	hypothetical protein; Provisional; Region: PRK01821
701347005199	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
701347005200	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
701347005201	FMN binding site [chemical binding]; other site
701347005202	active site
701347005203	catalytic residues [active]
701347005204	substrate binding site [chemical binding]; other site
701347005205	Methyltransferase domain; Region: Methyltransf_31; pfam13847
701347005206	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347005207	S-adenosylmethionine binding site [chemical binding]; other site
701347005208	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
701347005209	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
701347005210	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
701347005211	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
701347005212	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
701347005213	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
701347005214	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
701347005215	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
701347005216	D-lactate dehydrogenase; Provisional; Region: PRK11183
701347005217	FAD binding domain; Region: FAD_binding_4; pfam01565
701347005218	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
701347005219	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
701347005220	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
701347005221	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
701347005222	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
701347005223	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
701347005224	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
701347005225	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
701347005226	Walker A/P-loop; other site
701347005227	ATP binding site [chemical binding]; other site
701347005228	Q-loop/lid; other site
701347005229	ABC transporter signature motif; other site
701347005230	Walker B; other site
701347005231	D-loop; other site
701347005232	H-loop/switch region; other site
701347005233	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
701347005234	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
701347005235	hypothetical protein; Provisional; Region: PRK13681
701347005236	transcriptional regulator MirA; Provisional; Region: PRK15043
701347005237	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
701347005238	DNA binding residues [nucleotide binding]
701347005239	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
701347005240	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
701347005241	GAF domain; Region: GAF; pfam01590
701347005242	Histidine kinase; Region: His_kinase; pfam06580
701347005243	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347005244	ATP binding site [chemical binding]; other site
701347005245	Mg2+ binding site [ion binding]; other site
701347005246	G-X-G motif; other site
701347005247	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
701347005248	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347005249	active site
701347005250	phosphorylation site [posttranslational modification]
701347005251	intermolecular recognition site; other site
701347005252	dimerization interface [polypeptide binding]; other site
701347005253	LytTr DNA-binding domain; Region: LytTR; pfam04397
701347005254	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
701347005255	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
701347005256	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
701347005257	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
701347005258	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
701347005259	active site
701347005260	HIGH motif; other site
701347005261	KMSKS motif; other site
701347005262	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
701347005263	tRNA binding surface [nucleotide binding]; other site
701347005264	anticodon binding site; other site
701347005265	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
701347005266	dimer interface [polypeptide binding]; other site
701347005267	putative tRNA-binding site [nucleotide binding]; other site
701347005268	antiporter inner membrane protein; Provisional; Region: PRK11670
701347005269	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
701347005270	Walker A motif; other site
701347005271	putative acetyltransferase; Provisional; Region: PRK03624
701347005272	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347005273	Coenzyme A binding pocket [chemical binding]; other site
701347005274	Predicted integral membrane protein [Function unknown]; Region: COG5455
701347005275	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347005276	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347005277	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
701347005278	putative effector binding pocket; other site
701347005279	dimerization interface [polypeptide binding]; other site
701347005280	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
701347005281	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
701347005282	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
701347005283	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
701347005284	active site
701347005285	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
701347005286	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347005287	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347005288	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
701347005289	dimerization interface [polypeptide binding]; other site
701347005290	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347005291	Ligand Binding Site [chemical binding]; other site
701347005292	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
701347005293	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
701347005294	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
701347005295	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
701347005296	active site
701347005297	homotetramer interface [polypeptide binding]; other site
701347005298	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
701347005299	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
701347005300	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347005301	putative DNA binding site [nucleotide binding]; other site
701347005302	dimerization interface [polypeptide binding]; other site
701347005303	putative Zn2+ binding site [ion binding]; other site
701347005304	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
701347005305	substrate binding site [chemical binding]; other site
701347005306	multimerization interface [polypeptide binding]; other site
701347005307	ATP binding site [chemical binding]; other site
701347005308	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
701347005309	dimer interface [polypeptide binding]; other site
701347005310	substrate binding site [chemical binding]; other site
701347005311	ATP binding site [chemical binding]; other site
701347005312	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
701347005313	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347005314	DNA-binding site [nucleotide binding]; DNA binding site
701347005315	UTRA domain; Region: UTRA; pfam07702
701347005316	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347005317	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
701347005318	substrate binding site [chemical binding]; other site
701347005319	ATP binding site [chemical binding]; other site
701347005320	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
701347005321	nucleoside transporter; Region: 2A0110; TIGR00889
701347005322	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347005323	putative substrate translocation pore; other site
701347005324	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
701347005325	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
701347005326	putative active site; other site
701347005327	catalytic residue [active]
701347005328	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347005329	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347005330	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347005331	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347005332	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
701347005333	PapC N-terminal domain; Region: PapC_N; pfam13954
701347005334	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347005335	PapC C-terminal domain; Region: PapC_C; pfam13953
701347005336	Fimbrial protein; Region: Fimbrial; cl01416
701347005337	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347005338	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347005339	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347005340	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
701347005341	DNA binding site [nucleotide binding]
701347005342	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
701347005343	HicB family; Region: HicB; pfam05534
701347005344	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347005345	AAA domain; Region: AAA_13; pfam13166
701347005346	Walker A/P-loop; other site
701347005347	ATP binding site [chemical binding]; other site
701347005348	putative protease; Provisional; Region: PRK15452
701347005349	Peptidase family U32; Region: Peptidase_U32; pfam01136
701347005350	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
701347005351	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347005352	active site
701347005353	phosphorylation site [posttranslational modification]
701347005354	intermolecular recognition site; other site
701347005355	dimerization interface [polypeptide binding]; other site
701347005356	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347005357	DNA binding site [nucleotide binding]
701347005358	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
701347005359	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347005360	dimerization interface [polypeptide binding]; other site
701347005361	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347005362	dimer interface [polypeptide binding]; other site
701347005363	phosphorylation site [posttranslational modification]
701347005364	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347005365	ATP binding site [chemical binding]; other site
701347005366	Mg2+ binding site [ion binding]; other site
701347005367	G-X-G motif; other site
701347005368	putative transporter; Provisional; Region: PRK10504
701347005369	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347005370	putative substrate translocation pore; other site
701347005371	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
701347005372	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
701347005373	Protein export membrane protein; Region: SecD_SecF; cl14618
701347005374	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
701347005375	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347005376	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347005377	putative chaperone; Provisional; Region: PRK11678
701347005378	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
701347005379	nucleotide binding site [chemical binding]; other site
701347005380	putative NEF/HSP70 interaction site [polypeptide binding]; other site
701347005381	SBD interface [polypeptide binding]; other site
701347005382	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
701347005383	AlkA N-terminal domain; Region: AlkA_N; pfam06029
701347005384	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
701347005385	minor groove reading motif; other site
701347005386	helix-hairpin-helix signature motif; other site
701347005387	substrate binding pocket [chemical binding]; other site
701347005388	active site
701347005389	putative sialic acid transporter; Region: 2A0112; TIGR00891
701347005390	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347005391	putative substrate translocation pore; other site
701347005392	putative diguanylate cyclase; Provisional; Region: PRK09776
701347005393	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
701347005394	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347005395	putative active site [active]
701347005396	heme pocket [chemical binding]; other site
701347005397	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347005398	putative active site [active]
701347005399	heme pocket [chemical binding]; other site
701347005400	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347005401	putative active site [active]
701347005402	heme pocket [chemical binding]; other site
701347005403	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347005404	metal binding site [ion binding]; metal-binding site
701347005405	active site
701347005406	I-site; other site
701347005407	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347005408	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
701347005409	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
701347005410	ATP-binding site [chemical binding]; other site
701347005411	Sugar specificity; other site
701347005412	Pyrimidine base specificity; other site
701347005413	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
701347005414	trimer interface [polypeptide binding]; other site
701347005415	active site
701347005416	putative assembly protein; Provisional; Region: PRK10833
701347005417	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
701347005418	polysaccharide export protein Wza; Provisional; Region: PRK15078
701347005419	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
701347005420	SLBB domain; Region: SLBB; pfam10531
701347005421	SLBB domain; Region: SLBB; pfam10531
701347005422	Low molecular weight phosphatase family; Region: LMWPc; cd00115
701347005423	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
701347005424	active site
701347005425	tyrosine kinase; Provisional; Region: PRK11519
701347005426	Chain length determinant protein; Region: Wzz; pfam02706
701347005427	Chain length determinant protein; Region: Wzz; cl15801
701347005428	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
701347005429	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
701347005430	putative glycosyl transferase; Provisional; Region: PRK10018
701347005431	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
701347005432	active site
701347005433	putative acyl transferase; Provisional; Region: PRK10191
701347005434	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
701347005435	trimer interface [polypeptide binding]; other site
701347005436	active site
701347005437	substrate binding site [chemical binding]; other site
701347005438	CoA binding site [chemical binding]; other site
701347005439	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
701347005440	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
701347005441	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
701347005442	putative glycosyl transferase; Provisional; Region: PRK10063
701347005443	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
701347005444	metal-binding site
701347005445	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
701347005446	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
701347005447	putative trimer interface [polypeptide binding]; other site
701347005448	putative active site [active]
701347005449	putative substrate binding site [chemical binding]; other site
701347005450	putative CoA binding site [chemical binding]; other site
701347005451	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
701347005452	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
701347005453	NADP-binding site; other site
701347005454	homotetramer interface [polypeptide binding]; other site
701347005455	substrate binding site [chemical binding]; other site
701347005456	homodimer interface [polypeptide binding]; other site
701347005457	active site
701347005458	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
701347005459	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
701347005460	NADP binding site [chemical binding]; other site
701347005461	active site
701347005462	putative substrate binding site [chemical binding]; other site
701347005463	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
701347005464	active site
701347005465	GDP-Mannose binding site [chemical binding]; other site
701347005466	dimer interface [polypeptide binding]; other site
701347005467	modified nudix motif
701347005468	metal binding site [ion binding]; metal-binding site
701347005469	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
701347005470	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
701347005471	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
701347005472	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
701347005473	Substrate binding site; other site
701347005474	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
701347005475	phosphomannomutase CpsG; Provisional; Region: PRK15414
701347005476	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
701347005477	active site
701347005478	substrate binding site [chemical binding]; other site
701347005479	metal binding site [ion binding]; metal-binding site
701347005480	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
701347005481	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
701347005482	colanic acid exporter; Provisional; Region: PRK10459
701347005483	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
701347005484	colanic acid biosynthesis protein; Provisional; Region: PRK10017
701347005485	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
701347005486	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
701347005487	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
701347005488	putative ADP-binding pocket [chemical binding]; other site
701347005489	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
701347005490	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
701347005491	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
701347005492	active site
701347005493	tetramer interface; other site
701347005494	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
701347005495	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
701347005496	NAD binding site [chemical binding]; other site
701347005497	substrate binding site [chemical binding]; other site
701347005498	homodimer interface [polypeptide binding]; other site
701347005499	active site
701347005500	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
701347005501	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
701347005502	substrate binding site; other site
701347005503	tetramer interface; other site
701347005504	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
701347005505	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
701347005506	NADP binding site [chemical binding]; other site
701347005507	active site
701347005508	putative substrate binding site [chemical binding]; other site
701347005509	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
701347005510	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
701347005511	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
701347005512	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
701347005513	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
701347005514	Walker A/P-loop; other site
701347005515	ATP binding site [chemical binding]; other site
701347005516	Q-loop/lid; other site
701347005517	ABC transporter signature motif; other site
701347005518	Walker B; other site
701347005519	D-loop; other site
701347005520	H-loop/switch region; other site
701347005521	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
701347005522	putative carbohydrate binding site [chemical binding]; other site
701347005523	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
701347005524	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
701347005525	trimer interface [polypeptide binding]; other site
701347005526	active site
701347005527	substrate binding site [chemical binding]; other site
701347005528	CoA binding site [chemical binding]; other site
701347005529	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
701347005530	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
701347005531	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
701347005532	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
701347005533	putative homodimer interface [polypeptide binding]; other site
701347005534	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
701347005535	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
701347005536	Probable Catalytic site; other site
701347005537	metal-binding site
701347005538	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
701347005539	GtrA-like protein; Region: GtrA; pfam04138
701347005540	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
701347005541	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
701347005542	Ligand binding site; other site
701347005543	Putative Catalytic site; other site
701347005544	DXD motif; other site
701347005545	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
701347005546	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
701347005547	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
701347005548	active site
701347005549	homodimer interface [polypeptide binding]; other site
701347005550	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
701347005551	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
701347005552	active site
701347005553	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
701347005554	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
701347005555	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
701347005556	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
701347005557	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
701347005558	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
701347005559	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
701347005560	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
701347005561	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
701347005562	putative NAD(P) binding site [chemical binding]; other site
701347005563	active site
701347005564	putative substrate binding site [chemical binding]; other site
701347005565	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
701347005566	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
701347005567	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
701347005568	metal binding site [ion binding]; metal-binding site
701347005569	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
701347005570	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
701347005571	substrate binding site [chemical binding]; other site
701347005572	glutamase interaction surface [polypeptide binding]; other site
701347005573	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
701347005574	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
701347005575	catalytic residues [active]
701347005576	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
701347005577	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
701347005578	putative active site [active]
701347005579	oxyanion strand; other site
701347005580	catalytic triad [active]
701347005581	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
701347005582	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347005583	active site
701347005584	motif I; other site
701347005585	motif II; other site
701347005586	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
701347005587	putative active site pocket [active]
701347005588	4-fold oligomerization interface [polypeptide binding]; other site
701347005589	metal binding residues [ion binding]; metal-binding site
701347005590	3-fold/trimer interface [polypeptide binding]; other site
701347005591	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
701347005592	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347005593	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347005594	homodimer interface [polypeptide binding]; other site
701347005595	catalytic residue [active]
701347005596	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
701347005597	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
701347005598	NAD binding site [chemical binding]; other site
701347005599	dimerization interface [polypeptide binding]; other site
701347005600	product binding site; other site
701347005601	substrate binding site [chemical binding]; other site
701347005602	zinc binding site [ion binding]; other site
701347005603	catalytic residues [active]
701347005604	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
701347005605	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
701347005606	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
701347005607	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
701347005608	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
701347005609	putative NAD(P) binding site [chemical binding]; other site
701347005610	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347005611	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347005612	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347005613	dimerization interface [polypeptide binding]; other site
701347005614	amino acid transporter; Region: 2A0306; TIGR00909
701347005615	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347005616	dimerization interface [polypeptide binding]; other site
701347005617	putative DNA binding site [nucleotide binding]; other site
701347005618	putative Zn2+ binding site [ion binding]; other site
701347005619	elongation factor G; Reviewed; Region: PRK00007
701347005620	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
701347005621	G1 box; other site
701347005622	putative GEF interaction site [polypeptide binding]; other site
701347005623	GTP/Mg2+ binding site [chemical binding]; other site
701347005624	Switch I region; other site
701347005625	G2 box; other site
701347005626	G3 box; other site
701347005627	Switch II region; other site
701347005628	G4 box; other site
701347005629	G5 box; other site
701347005630	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
701347005631	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
701347005632	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
701347005633	exonuclease I; Provisional; Region: sbcB; PRK11779
701347005634	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
701347005635	active site
701347005636	catalytic site [active]
701347005637	substrate binding site [chemical binding]; other site
701347005638	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
701347005639	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
701347005640	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
701347005641	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
701347005642	DNA gyrase inhibitor; Provisional; Region: PRK10016
701347005643	Predicted membrane protein [Function unknown]; Region: COG1289
701347005644	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
701347005645	hypothetical protein; Provisional; Region: PRK05423
701347005646	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
701347005647	Predicted permeases [General function prediction only]; Region: COG0679
701347005648	malate dehydrogenase; Provisional; Region: PRK13529
701347005649	Malic enzyme, N-terminal domain; Region: malic; pfam00390
701347005650	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
701347005651	NAD(P) binding site [chemical binding]; other site
701347005652	fumarate hydratase; Provisional; Region: PRK15389
701347005653	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
701347005654	Fumarase C-terminus; Region: Fumerase_C; pfam05683
701347005655	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
701347005656	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
701347005657	transmembrane helices; other site
701347005658	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
701347005659	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
701347005660	putative active site [active]
701347005661	putative FMN binding site [chemical binding]; other site
701347005662	putative substrate binding site [chemical binding]; other site
701347005663	putative catalytic residue [active]
701347005664	FMN-binding domain; Region: FMN_bind; cl01081
701347005665	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
701347005666	L-aspartate oxidase; Provisional; Region: PRK06175
701347005667	Predicted oxidoreductase [General function prediction only]; Region: COG3573
701347005668	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
701347005669	ApbE family; Region: ApbE; pfam02424
701347005670	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
701347005671	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347005672	active site
701347005673	phosphorylation site [posttranslational modification]
701347005674	intermolecular recognition site; other site
701347005675	dimerization interface [polypeptide binding]; other site
701347005676	Transcriptional regulator; Region: CitT; pfam12431
701347005677	sensory histidine kinase DcuS; Provisional; Region: PRK11086
701347005678	PAS domain; Region: PAS; smart00091
701347005679	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347005680	ATP binding site [chemical binding]; other site
701347005681	Mg2+ binding site [ion binding]; other site
701347005682	G-X-G motif; other site
701347005683	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
701347005684	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
701347005685	putative active site [active]
701347005686	Peptidase M14-like domain; uncharacterized subfamily; Region: M14-like_4; cd06231
701347005687	putative active site [active]
701347005688	Zn binding site [ion binding]; other site
701347005689	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
701347005690	active site
701347005691	putative transposase OrfB; Reviewed; Region: PHA02517
701347005692	HTH-like domain; Region: HTH_21; pfam13276
701347005693	Integrase core domain; Region: rve; pfam00665
701347005694	Integrase core domain; Region: rve_3; pfam13683
701347005695	Transposase; Region: HTH_Tnp_1; pfam01527
701347005696	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
701347005697	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
701347005698	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
701347005699	PemK-like protein; Region: PemK; cl00995
701347005700	MATE family multidrug exporter; Provisional; Region: PRK10189
701347005701	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
701347005702	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
701347005703	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
701347005704	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
701347005705	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
701347005706	NAD(P) binding site [chemical binding]; other site
701347005707	catalytic residues [active]
701347005708	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
701347005709	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347005710	non-specific DNA binding site [nucleotide binding]; other site
701347005711	salt bridge; other site
701347005712	sequence-specific DNA binding site [nucleotide binding]; other site
701347005713	Cupin domain; Region: Cupin_2; pfam07883
701347005714	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
701347005715	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
701347005716	catalytic triad [active]
701347005717	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
701347005718	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
701347005719	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
701347005720	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347005721	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347005722	trimer interface [polypeptide binding]; other site
701347005723	eyelet of channel; other site
701347005724	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
701347005725	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
701347005726	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
701347005727	active site
701347005728	AMP nucleosidase; Provisional; Region: PRK08292
701347005729	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
701347005730	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
701347005731	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
701347005732	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347005733	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
701347005734	putative dimerization interface [polypeptide binding]; other site
701347005735	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
701347005736	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347005737	dimerization interface [polypeptide binding]; other site
701347005738	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
701347005739	L,D-transpeptidase; Provisional; Region: PRK10190
701347005740	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347005741	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347005742	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
701347005743	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347005744	dimerization interface [polypeptide binding]; other site
701347005745	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
701347005746	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
701347005747	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
701347005748	homodimer interface [polypeptide binding]; other site
701347005749	Walker A motif; other site
701347005750	ATP binding site [chemical binding]; other site
701347005751	hydroxycobalamin binding site [chemical binding]; other site
701347005752	Walker B motif; other site
701347005753	putative fumarate hydratase; Provisional; Region: PRK15392
701347005754	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
701347005755	Fumarase C-terminus; Region: Fumerase_C; pfam05683
701347005756	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
701347005757	Glutaminase; Region: Glutaminase; cl00907
701347005758	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
701347005759	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
701347005760	Domain of unknown function (DUF4387); Region: DUF4387; pfam14330
701347005761	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
701347005762	Methylaspartate ammonia-lyase [Amino acid transport and metabolism]; Region: Mal; COG3799
701347005763	Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the...; Region: MAL; cd03314
701347005764	dimer interface [polypeptide binding]; other site
701347005765	active site
701347005766	Coenzyme B12-dependent glutamate mutase epsilon subunit-like family; contains proteins similar to Clostridium cochlearium glutamate mutase (Glm) and Streptomyces tendae Tu901 NikV. Glm catalyzes a carbon-skeleton rearrangement of L-glutamate to...; Region: Glm_e; cd00245
701347005767	substrate binding site [chemical binding]; other site
701347005768	B12 cofactor binding site [chemical binding]; other site
701347005769	heterodimer (sigma-epsilon) interface [polypeptide binding]; other site
701347005770	homodimer (epsilon-epsilon) interface [polypeptide binding]; other site
701347005771	conserved hypothetical protein; Region: glmL_fam; TIGR01319
701347005772	B12 binding domain of glutamate mutase (Glm). Glutamate mutase catalysis the conversion of (S)-glutamate with (2S,3S)-3-methylaspartate. The rearrangement reaction is initiated by the extraction of a hydrogen from the protein-bound substrate by a 5'...; Region: Glm_B12_BD; cd02072
701347005773	B12 binding site [chemical binding]; other site
701347005774	heterodimer interface [polypeptide binding]; other site
701347005775	cobalt ligand [ion binding]; other site
701347005776	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
701347005777	active site
701347005778	SAM binding site [chemical binding]; other site
701347005779	homodimer interface [polypeptide binding]; other site
701347005780	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
701347005781	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347005782	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347005783	homodimer interface [polypeptide binding]; other site
701347005784	catalytic residue [active]
701347005785	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
701347005786	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
701347005787	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
701347005788	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
701347005789	propionate kinase; Reviewed; Region: PRK12397
701347005790	propionate/acetate kinase; Provisional; Region: PRK12379
701347005791	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
701347005792	G1 box; other site
701347005793	GTP/Mg2+ binding site [chemical binding]; other site
701347005794	G2 box; other site
701347005795	G3 box; other site
701347005796	Switch II region; other site
701347005797	G4 box; other site
701347005798	G5 box; other site
701347005799	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
701347005800	putative hexamer interface [polypeptide binding]; other site
701347005801	putative hexagonal pore; other site
701347005802	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
701347005803	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
701347005804	putative hexamer interface [polypeptide binding]; other site
701347005805	putative hexagonal pore; other site
701347005806	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
701347005807	putative hexamer interface [polypeptide binding]; other site
701347005808	putative hexagonal pore; other site
701347005809	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
701347005810	SLBB domain; Region: SLBB; pfam10531
701347005811	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
701347005812	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
701347005813	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
701347005814	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
701347005815	putative active site [active]
701347005816	metal binding site [ion binding]; metal-binding site
701347005817	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
701347005818	putative catalytic cysteine [active]
701347005819	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
701347005820	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
701347005821	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cl01889
701347005822	Hexamer/Pentamer interface [polypeptide binding]; other site
701347005823	central pore; other site
701347005824	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
701347005825	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
701347005826	Propanediol utilisation protein PduL; Region: PduL; pfam06130
701347005827	Propanediol utilisation protein PduL; Region: PduL; pfam06130
701347005828	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
701347005829	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
701347005830	putative hexamer interface [polypeptide binding]; other site
701347005831	putative hexagonal pore; other site
701347005832	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
701347005833	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
701347005834	Hexamer interface [polypeptide binding]; other site
701347005835	Putative hexagonal pore residue; other site
701347005836	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
701347005837	Cell division protein FtsA; Region: FtsA; cl17206
701347005838	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
701347005839	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
701347005840	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
701347005841	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
701347005842	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
701347005843	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
701347005844	alpha-beta subunit interface [polypeptide binding]; other site
701347005845	alpha-gamma subunit interface [polypeptide binding]; other site
701347005846	active site
701347005847	substrate and K+ binding site; other site
701347005848	K+ binding site [ion binding]; other site
701347005849	cobalamin binding site [chemical binding]; other site
701347005850	propanediol utilization protein PduB; Provisional; Region: PRK15415
701347005851	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
701347005852	putative hexamer interface [polypeptide binding]; other site
701347005853	putative hexagonal pore; other site
701347005854	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
701347005855	putative hexamer interface [polypeptide binding]; other site
701347005856	putative hexagonal pore; other site
701347005857	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
701347005858	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
701347005859	Hexamer interface [polypeptide binding]; other site
701347005860	Putative hexagonal pore residue; other site
701347005861	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
701347005862	amphipathic channel; other site
701347005863	Asn-Pro-Ala signature motifs; other site
701347005864	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
701347005865	Sensory domain found in PocR; Region: PocR; pfam10114
701347005866	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347005867	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347005868	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347005869	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
701347005870	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
701347005871	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
701347005872	catalytic triad [active]
701347005873	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
701347005874	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
701347005875	Precorrin-8X methylmutase; Region: CbiC; pfam02570
701347005876	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
701347005877	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
701347005878	active site
701347005879	putative homodimer interface [polypeptide binding]; other site
701347005880	SAM binding site [chemical binding]; other site
701347005881	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
701347005882	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347005883	S-adenosylmethionine binding site [chemical binding]; other site
701347005884	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
701347005885	active site
701347005886	SAM binding site [chemical binding]; other site
701347005887	homodimer interface [polypeptide binding]; other site
701347005888	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
701347005889	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
701347005890	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
701347005891	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
701347005892	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
701347005893	active site
701347005894	SAM binding site [chemical binding]; other site
701347005895	homodimer interface [polypeptide binding]; other site
701347005896	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
701347005897	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
701347005898	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
701347005899	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
701347005900	active site
701347005901	C-terminal domain interface [polypeptide binding]; other site
701347005902	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
701347005903	active site
701347005904	N-terminal domain interface [polypeptide binding]; other site
701347005905	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
701347005906	active site
701347005907	SAM binding site [chemical binding]; other site
701347005908	homodimer interface [polypeptide binding]; other site
701347005909	cobalt transport protein CbiM; Validated; Region: PRK08319
701347005910	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
701347005911	cobalt transport protein CbiN; Provisional; Region: PRK02898
701347005912	cobalt transport protein CbiQ; Provisional; Region: PRK15485
701347005913	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
701347005914	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
701347005915	Walker A/P-loop; other site
701347005916	ATP binding site [chemical binding]; other site
701347005917	Q-loop/lid; other site
701347005918	ABC transporter signature motif; other site
701347005919	Walker B; other site
701347005920	D-loop; other site
701347005921	H-loop/switch region; other site
701347005922	cobyric acid synthase; Provisional; Region: PRK00784
701347005923	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
701347005924	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
701347005925	catalytic triad [active]
701347005926	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
701347005927	homotrimer interface [polypeptide binding]; other site
701347005928	Walker A motif; other site
701347005929	GTP binding site [chemical binding]; other site
701347005930	Walker B motif; other site
701347005931	cobalamin synthase; Reviewed; Region: cobS; PRK00235
701347005932	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
701347005933	catalytic core [active]
701347005934	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
701347005935	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
701347005936	putative dimer interface [polypeptide binding]; other site
701347005937	active site pocket [active]
701347005938	putative cataytic base [active]
701347005939	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
701347005940	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
701347005941	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
701347005942	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
701347005943	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
701347005944	Autotransporter beta-domain; Region: Autotransporter; pfam03797
701347005945	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
701347005946	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347005947	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
701347005948	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
701347005949	active site residue [active]
701347005950	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
701347005951	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347005952	Hemerythrin-like domain; Region: Hr-like; cd12108
701347005953	Fe binding site [ion binding]; other site
701347005954	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347005955	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347005956	trimer interface [polypeptide binding]; other site
701347005957	eyelet of channel; other site
701347005958	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
701347005959	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
701347005960	Zn2+ binding site [ion binding]; other site
701347005961	Mg2+ binding site [ion binding]; other site
701347005962	DNA cytosine methylase; Provisional; Region: PRK10458
701347005963	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
701347005964	cofactor binding site; other site
701347005965	DNA binding site [nucleotide binding]
701347005966	substrate interaction site [chemical binding]; other site
701347005967	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
701347005968	additional DNA contacts [nucleotide binding]; other site
701347005969	mismatch recognition site; other site
701347005970	active site
701347005971	zinc binding site [ion binding]; other site
701347005972	DNA intercalation site [nucleotide binding]; other site
701347005973	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
701347005974	EamA-like transporter family; Region: EamA; pfam00892
701347005975	EamA-like transporter family; Region: EamA; pfam00892
701347005976	hypothetical protein; Provisional; Region: PRK10062
701347005977	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
701347005978	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347005979	metal binding site [ion binding]; metal-binding site
701347005980	active site
701347005981	I-site; other site
701347005982	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
701347005983	hypothetical protein; Provisional; Region: PRK10708
701347005984	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
701347005985	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347005986	DNA binding residues [nucleotide binding]
701347005987	dimerization interface [polypeptide binding]; other site
701347005988	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
701347005989	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
701347005990	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
701347005991	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
701347005992	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
701347005993	flagellar motor switch protein; Validated; Region: fliN; PRK05698
701347005994	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
701347005995	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
701347005996	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
701347005997	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
701347005998	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
701347005999	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
701347006000	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
701347006001	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
701347006002	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
701347006003	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
701347006004	Walker A motif/ATP binding site; other site
701347006005	Walker B motif; other site
701347006006	flagellar assembly protein H; Validated; Region: fliH; PRK05687
701347006007	Flagellar assembly protein FliH; Region: FliH; pfam02108
701347006008	flagellar motor switch protein FliG; Region: fliG; TIGR00207
701347006009	FliG C-terminal domain; Region: FliG_C; pfam01706
701347006010	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
701347006011	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
701347006012	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
701347006013	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
701347006014	TolA C-terminal; Region: TolA; pfam06519
701347006015	lipoprotein; Provisional; Region: PRK10397
701347006016	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
701347006017	flagellar protein FliS; Validated; Region: fliS; PRK05685
701347006018	flagellar capping protein; Reviewed; Region: fliD; PRK08032
701347006019	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
701347006020	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
701347006021	flagellin; Validated; Region: PRK06819
701347006022	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
701347006023	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
701347006024	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
701347006025	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
701347006026	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
701347006027	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
701347006028	DNA binding residues [nucleotide binding]
701347006029	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
701347006030	cystine transporter subunit; Provisional; Region: PRK11260
701347006031	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347006032	substrate binding pocket [chemical binding]; other site
701347006033	membrane-bound complex binding site; other site
701347006034	hinge residues; other site
701347006035	D-cysteine desulfhydrase; Validated; Region: PRK03910
701347006036	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
701347006037	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347006038	catalytic residue [active]
701347006039	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347006040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006041	dimer interface [polypeptide binding]; other site
701347006042	conserved gate region; other site
701347006043	putative PBP binding loops; other site
701347006044	ABC-ATPase subunit interface; other site
701347006045	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
701347006046	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347006047	Walker A/P-loop; other site
701347006048	ATP binding site [chemical binding]; other site
701347006049	Q-loop/lid; other site
701347006050	ABC transporter signature motif; other site
701347006051	Walker B; other site
701347006052	D-loop; other site
701347006053	H-loop/switch region; other site
701347006054	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
701347006055	CoA-transferase family III; Region: CoA_transf_3; pfam02515
701347006056	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
701347006057	Autoinducer binding domain; Region: Autoind_bind; pfam03472
701347006058	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347006059	DNA binding residues [nucleotide binding]
701347006060	dimerization interface [polypeptide binding]; other site
701347006061	hypothetical protein; Provisional; Region: PRK10613
701347006062	response regulator; Provisional; Region: PRK09483
701347006063	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347006064	active site
701347006065	phosphorylation site [posttranslational modification]
701347006066	intermolecular recognition site; other site
701347006067	dimerization interface [polypeptide binding]; other site
701347006068	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347006069	DNA binding residues [nucleotide binding]
701347006070	dimerization interface [polypeptide binding]; other site
701347006071	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
701347006072	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
701347006073	GIY-YIG motif/motif A; other site
701347006074	active site
701347006075	catalytic site [active]
701347006076	putative DNA binding site [nucleotide binding]; other site
701347006077	metal binding site [ion binding]; metal-binding site
701347006078	UvrB/uvrC motif; Region: UVR; pfam02151
701347006079	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
701347006080	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
701347006081	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
701347006082	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
701347006083	active site
701347006084	DNA binding site [nucleotide binding]
701347006085	Int/Topo IB signature motif; other site
701347006086	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
701347006087	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
701347006088	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
701347006089	active site
701347006090	substrate binding site [chemical binding]; other site
701347006091	catalytic site [active]
701347006092	transcriptional repressor DicA; Reviewed; Region: PRK09706
701347006093	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347006094	non-specific DNA binding site [nucleotide binding]; other site
701347006095	salt bridge; other site
701347006096	sequence-specific DNA binding site [nucleotide binding]; other site
701347006097	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347006098	non-specific DNA binding site [nucleotide binding]; other site
701347006099	salt bridge; other site
701347006100	sequence-specific DNA binding site [nucleotide binding]; other site
701347006101	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
701347006102	Protein of unknown function (DUF1376); Region: DUF1376; cl01531
701347006103	primosomal protein DnaI; Provisional; Region: PRK02854
701347006104	putative replication protein; Provisional; Region: PRK12377
701347006105	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347006106	Walker A motif; other site
701347006107	ATP binding site [chemical binding]; other site
701347006108	PerC transcriptional activator; Region: PerC; pfam06069
701347006109	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
701347006110	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
701347006111	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
701347006112	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
701347006113	cofactor binding site; other site
701347006114	DNA binding site [nucleotide binding]
701347006115	substrate interaction site [chemical binding]; other site
701347006116	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
701347006117	DinI-like family; Region: DinI; cl11630
701347006118	Endodeoxyribonuclease RusA; Region: RusA; cl01885
701347006119	Protein of unknown function (DUF968); Region: DUF968; pfam06147
701347006120	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
701347006121	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
701347006122	Protein of unknown function (DUF754); Region: DUF754; pfam05449
701347006123	TIGR02594 family protein; Region: TIGR02594
701347006124	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
701347006125	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
701347006126	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
701347006127	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
701347006128	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
701347006129	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
701347006130	oligomer interface [polypeptide binding]; other site
701347006131	active site residues [active]
701347006132	Uncharacterized conserved protein [Function unknown]; Region: COG5471
701347006133	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
701347006134	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
701347006135	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
701347006136	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
701347006137	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
701347006138	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; cl06106
701347006139	Minor tail protein T; Region: Phage_tail_T; cl05636
701347006140	Phage-related minor tail protein [Function unknown]; Region: COG5281
701347006141	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
701347006142	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
701347006143	Phage minor tail protein; Region: Phage_min_tail; pfam05939
701347006144	Phage minor tail protein L; Region: Phage_tail_L; cl01908
701347006145	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
701347006146	MPN+ (JAMM) motif; other site
701347006147	Zinc-binding site [ion binding]; other site
701347006148	NlpC/P60 family; Region: NLPC_P60; pfam00877
701347006149	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
701347006150	Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane]; Region: COG3056
701347006151	Phage-related protein, tail component [Function unknown]; Region: COG4723
701347006152	Phage-related protein, tail component [Function unknown]; Region: COG4733
701347006153	Putative phage tail protein; Region: Phage-tail_3; pfam13550
701347006154	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
701347006155	Interdomain contacts; other site
701347006156	Cytokine receptor motif; other site
701347006157	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
701347006158	Fibronectin type III protein; Region: DUF3672; pfam12421
701347006159	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
701347006160	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
701347006161	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
701347006162	Catalytic site [active]
701347006163	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
701347006164	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
701347006165	active site
701347006166	DNA binding site [nucleotide binding]
701347006167	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
701347006168	hypothetical protein; Provisional; Region: PRK09951
701347006169	hypothetical protein; Provisional; Region: PRK10396
701347006170	yecA family protein; Region: ygfB_yecA; TIGR02292
701347006171	SEC-C motif; Region: SEC-C; pfam02810
701347006172	tyrosine transporter TyrP; Provisional; Region: PRK15132
701347006173	aromatic amino acid transport protein; Region: araaP; TIGR00837
701347006174	probable metal-binding protein; Region: matur_matur; TIGR03853
701347006175	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
701347006176	Ferritin-like domain; Region: Ferritin; pfam00210
701347006177	ferroxidase diiron center [ion binding]; other site
701347006178	YecR-like lipoprotein; Region: YecR; pfam13992
701347006179	hypothetical protein; Provisional; Region: PRK09273
701347006180	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
701347006181	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
701347006182	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347006183	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347006184	putative substrate translocation pore; other site
701347006185	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
701347006186	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
701347006187	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
701347006188	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
701347006189	Ferritin-like domain; Region: Ferritin; pfam00210
701347006190	ferroxidase diiron center [ion binding]; other site
701347006191	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
701347006192	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
701347006193	ligand binding site [chemical binding]; other site
701347006194	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
701347006195	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347006196	Walker A/P-loop; other site
701347006197	ATP binding site [chemical binding]; other site
701347006198	Q-loop/lid; other site
701347006199	ABC transporter signature motif; other site
701347006200	Walker B; other site
701347006201	D-loop; other site
701347006202	H-loop/switch region; other site
701347006203	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347006204	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347006205	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347006206	TM-ABC transporter signature motif; other site
701347006207	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347006208	Ligand Binding Site [chemical binding]; other site
701347006209	transcriptional activator FlhD; Provisional; Region: PRK02909
701347006210	transcriptional activator FlhC; Provisional; Region: PRK12722
701347006211	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
701347006212	flagellar motor protein MotA; Validated; Region: PRK09110
701347006213	flagellar motor protein MotB; Validated; Region: motB; PRK09041
701347006214	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
701347006215	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347006216	ligand binding site [chemical binding]; other site
701347006217	chemotaxis protein CheA; Provisional; Region: PRK10547
701347006218	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
701347006219	putative binding surface; other site
701347006220	active site
701347006221	CheY binding; Region: CheY-binding; pfam09078
701347006222	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
701347006223	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347006224	ATP binding site [chemical binding]; other site
701347006225	Mg2+ binding site [ion binding]; other site
701347006226	G-X-G motif; other site
701347006227	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
701347006228	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
701347006229	putative CheA interaction surface; other site
701347006230	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
701347006231	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
701347006232	dimer interface [polypeptide binding]; other site
701347006233	ligand binding site [chemical binding]; other site
701347006234	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347006235	dimerization interface [polypeptide binding]; other site
701347006236	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347006237	dimer interface [polypeptide binding]; other site
701347006238	putative CheW interface [polypeptide binding]; other site
701347006239	methyl-accepting protein IV; Provisional; Region: PRK09793
701347006240	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
701347006241	dimer interface [polypeptide binding]; other site
701347006242	ligand binding site [chemical binding]; other site
701347006243	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347006244	dimerization interface [polypeptide binding]; other site
701347006245	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347006246	dimer interface [polypeptide binding]; other site
701347006247	putative CheW interface [polypeptide binding]; other site
701347006248	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
701347006249	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
701347006250	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347006251	S-adenosylmethionine binding site [chemical binding]; other site
701347006252	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
701347006253	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347006254	active site
701347006255	phosphorylation site [posttranslational modification]
701347006256	intermolecular recognition site; other site
701347006257	dimerization interface [polypeptide binding]; other site
701347006258	CheB methylesterase; Region: CheB_methylest; pfam01339
701347006259	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
701347006260	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347006261	active site
701347006262	phosphorylation site [posttranslational modification]
701347006263	intermolecular recognition site; other site
701347006264	dimerization interface [polypeptide binding]; other site
701347006265	chemotaxis regulator CheZ; Provisional; Region: PRK11166
701347006266	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
701347006267	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
701347006268	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
701347006269	FHIPEP family; Region: FHIPEP; pfam00771
701347006270	Flagellar protein FlhE; Region: FlhE; pfam06366
701347006271	penicillin-binding protein 2; Provisional; Region: PRK10795
701347006272	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
701347006273	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
701347006274	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
701347006275	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
701347006276	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
701347006277	active site
701347006278	HIGH motif; other site
701347006279	KMSK motif region; other site
701347006280	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
701347006281	tRNA binding surface [nucleotide binding]; other site
701347006282	anticodon binding site; other site
701347006283	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
701347006284	putative metal binding site [ion binding]; other site
701347006285	copper homeostasis protein CutC; Provisional; Region: PRK11572
701347006286	Methyltransferase domain; Region: Methyltransf_23; pfam13489
701347006287	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347006288	S-adenosylmethionine binding site [chemical binding]; other site
701347006289	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347006290	S-adenosylmethionine binding site [chemical binding]; other site
701347006291	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
701347006292	hypothetical protein; Provisional; Region: PRK10302
701347006293	Isochorismatase family; Region: Isochorismatase; pfam00857
701347006294	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
701347006295	catalytic triad [active]
701347006296	conserved cis-peptide bond; other site
701347006297	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
701347006298	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
701347006299	dimer interface [polypeptide binding]; other site
701347006300	anticodon binding site; other site
701347006301	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
701347006302	homodimer interface [polypeptide binding]; other site
701347006303	motif 1; other site
701347006304	active site
701347006305	motif 2; other site
701347006306	GAD domain; Region: GAD; pfam02938
701347006307	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
701347006308	active site
701347006309	motif 3; other site
701347006310	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
701347006311	nudix motif; other site
701347006312	hypothetical protein; Validated; Region: PRK00110
701347006313	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
701347006314	active site
701347006315	putative DNA-binding cleft [nucleotide binding]; other site
701347006316	dimer interface [polypeptide binding]; other site
701347006317	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
701347006318	RuvA N terminal domain; Region: RuvA_N; pfam01330
701347006319	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
701347006320	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
701347006321	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347006322	Walker A motif; other site
701347006323	ATP binding site [chemical binding]; other site
701347006324	Walker B motif; other site
701347006325	arginine finger; other site
701347006326	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
701347006327	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
701347006328	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347006329	ABC-ATPase subunit  interface; other site
701347006330	dimer interface [polypeptide binding]; other site
701347006331	putative PBP binding regions; other site
701347006332	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
701347006333	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
701347006334	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
701347006335	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
701347006336	metal binding site [ion binding]; metal-binding site
701347006337	putative peptidase; Provisional; Region: PRK11649
701347006338	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
701347006339	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347006340	Peptidase family M23; Region: Peptidase_M23; pfam01551
701347006341	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
701347006342	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
701347006343	putative acyl-acceptor binding pocket; other site
701347006344	pyruvate kinase; Provisional; Region: PRK05826
701347006345	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
701347006346	domain interfaces; other site
701347006347	active site
701347006348	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
701347006349	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347006350	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347006351	putative active site [active]
701347006352	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
701347006353	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
701347006354	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
701347006355	phosphogluconate dehydratase; Validated; Region: PRK09054
701347006356	6-phosphogluconate dehydratase; Region: edd; TIGR01196
701347006357	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
701347006358	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
701347006359	active site
701347006360	intersubunit interface [polypeptide binding]; other site
701347006361	catalytic residue [active]
701347006362	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
701347006363	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
701347006364	ATP-grasp domain; Region: ATP-grasp; pfam02222
701347006365	YebF-like protein; Region: YebF; cl10126
701347006366	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
701347006367	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
701347006368	putative metal binding site [ion binding]; other site
701347006369	protease 2; Provisional; Region: PRK10115
701347006370	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
701347006371	exodeoxyribonuclease X; Provisional; Region: PRK07983
701347006372	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
701347006373	active site
701347006374	catalytic site [active]
701347006375	substrate binding site [chemical binding]; other site
701347006376	Predicted amidohydrolase [General function prediction only]; Region: COG0388
701347006377	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
701347006378	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
701347006379	CopC domain; Region: CopC; cl01012
701347006380	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
701347006381	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
701347006382	phage resistance protein; Provisional; Region: PRK10551
701347006383	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
701347006384	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347006385	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
701347006386	Protein of unknown function (DUF535); Region: DUF535; pfam04393
701347006387	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
701347006388	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
701347006389	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
701347006390	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
701347006391	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347006392	S-adenosylmethionine binding site [chemical binding]; other site
701347006393	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
701347006394	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
701347006395	mce related protein; Region: MCE; pfam02470
701347006396	mce related protein; Region: MCE; pfam02470
701347006397	mce related protein; Region: MCE; pfam02470
701347006398	mce related protein; Region: MCE; pfam02470
701347006399	mce related protein; Region: MCE; pfam02470
701347006400	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
701347006401	Paraquat-inducible protein A; Region: PqiA; pfam04403
701347006402	Paraquat-inducible protein A; Region: PqiA; pfam04403
701347006403	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
701347006404	GAF domain; Region: GAF_2; pfam13185
701347006405	ProP expression regulator; Provisional; Region: PRK04950
701347006406	ProQ/FINO family; Region: ProQ; pfam04352
701347006407	carboxy-terminal protease; Provisional; Region: PRK11186
701347006408	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
701347006409	protein binding site [polypeptide binding]; other site
701347006410	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
701347006411	Catalytic dyad [active]
701347006412	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
701347006413	heat shock protein HtpX; Provisional; Region: PRK05457
701347006414	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
701347006415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347006416	putative substrate translocation pore; other site
701347006417	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
701347006418	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347006419	dimerization interface [polypeptide binding]; other site
701347006420	putative Zn2+ binding site [ion binding]; other site
701347006421	putative DNA binding site [nucleotide binding]; other site
701347006422	Bacterial transcriptional regulator; Region: IclR; pfam01614
701347006423	YobH-like protein; Region: YobH; pfam13996
701347006424	MgrB protein; Region: MgrB; cl08105
701347006425	YebO-like protein; Region: YebO; pfam13974
701347006426	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
701347006427	DNA-binding site [nucleotide binding]; DNA binding site
701347006428	RNA-binding motif; other site
701347006429	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
701347006430	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
701347006431	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
701347006432	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
701347006433	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347006434	S-adenosylmethionine binding site [chemical binding]; other site
701347006435	hypothetical protein; Provisional; Region: PRK11469
701347006436	Domain of unknown function DUF; Region: DUF204; pfam02659
701347006437	Domain of unknown function DUF; Region: DUF204; pfam02659
701347006438	hypothetical protein; Provisional; Region: PRK02913
701347006439	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
701347006440	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
701347006441	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
701347006442	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
701347006443	active pocket/dimerization site; other site
701347006444	active site
701347006445	phosphorylation site [posttranslational modification]
701347006446	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
701347006447	active site
701347006448	phosphorylation site [posttranslational modification]
701347006449	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
701347006450	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
701347006451	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
701347006452	Transporter associated domain; Region: CorC_HlyC; smart01091
701347006453	L-serine deaminase; Provisional; Region: PRK15023
701347006454	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
701347006455	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
701347006456	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
701347006457	putative active site [active]
701347006458	putative CoA binding site [chemical binding]; other site
701347006459	nudix motif; other site
701347006460	metal binding site [ion binding]; metal-binding site
701347006461	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
701347006462	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
701347006463	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
701347006464	hypothetical protein; Provisional; Region: PRK05114
701347006465	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
701347006466	homotrimer interaction site [polypeptide binding]; other site
701347006467	putative active site [active]
701347006468	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
701347006469	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
701347006470	DEAD_2; Region: DEAD_2; pfam06733
701347006471	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
701347006472	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
701347006473	Glycoprotease family; Region: Peptidase_M22; pfam00814
701347006474	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
701347006475	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
701347006476	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
701347006477	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
701347006478	acyl-activating enzyme (AAE) consensus motif; other site
701347006479	putative AMP binding site [chemical binding]; other site
701347006480	putative active site [active]
701347006481	putative CoA binding site [chemical binding]; other site
701347006482	ribonuclease D; Provisional; Region: PRK10829
701347006483	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
701347006484	catalytic site [active]
701347006485	putative active site [active]
701347006486	putative substrate binding site [chemical binding]; other site
701347006487	Helicase and RNase D C-terminal; Region: HRDC; smart00341
701347006488	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
701347006489	cell division inhibitor MinD; Provisional; Region: PRK10818
701347006490	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
701347006491	Switch I; other site
701347006492	Switch II; other site
701347006493	septum formation inhibitor; Reviewed; Region: minC; PRK03511
701347006494	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
701347006495	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
701347006496	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
701347006497	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
701347006498	hypothetical protein; Provisional; Region: PRK10691
701347006499	hypothetical protein; Provisional; Region: PRK05170
701347006500	disulfide bond formation protein B; Provisional; Region: PRK01749
701347006501	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
701347006502	fatty acid metabolism regulator; Provisional; Region: PRK04984
701347006503	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347006504	DNA-binding site [nucleotide binding]; DNA binding site
701347006505	FadR C-terminal domain; Region: FadR_C; pfam07840
701347006506	SpoVR family protein; Provisional; Region: PRK11767
701347006507	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
701347006508	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
701347006509	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
701347006510	alanine racemase; Reviewed; Region: dadX; PRK03646
701347006511	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
701347006512	active site
701347006513	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
701347006514	substrate binding site [chemical binding]; other site
701347006515	catalytic residues [active]
701347006516	dimer interface [polypeptide binding]; other site
701347006517	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
701347006518	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
701347006519	TrkA-C domain; Region: TrkA_C; pfam02080
701347006520	Transporter associated domain; Region: CorC_HlyC; smart01091
701347006521	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
701347006522	dimer interface [polypeptide binding]; other site
701347006523	catalytic triad [active]
701347006524	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
701347006525	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347006526	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347006527	catalytic residue [active]
701347006528	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
701347006529	Flagellar regulator YcgR; Region: YcgR; pfam07317
701347006530	PilZ domain; Region: PilZ; pfam07238
701347006531	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
701347006532	Trehalase; Region: Trehalase; cl17346
701347006533	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
701347006534	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
701347006535	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
701347006536	Walker A/P-loop; other site
701347006537	ATP binding site [chemical binding]; other site
701347006538	Q-loop/lid; other site
701347006539	ABC transporter signature motif; other site
701347006540	Walker B; other site
701347006541	D-loop; other site
701347006542	H-loop/switch region; other site
701347006543	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
701347006544	Transferrin; Region: Transferrin; cl02460
701347006545	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
701347006546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006547	dimer interface [polypeptide binding]; other site
701347006548	conserved gate region; other site
701347006549	putative PBP binding loops; other site
701347006550	ABC-ATPase subunit interface; other site
701347006551	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
701347006552	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006553	dimer interface [polypeptide binding]; other site
701347006554	conserved gate region; other site
701347006555	putative PBP binding loops; other site
701347006556	ABC-ATPase subunit interface; other site
701347006557	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
701347006558	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
701347006559	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
701347006560	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
701347006561	ATP binding site [chemical binding]; other site
701347006562	Mg++ binding site [ion binding]; other site
701347006563	motif III; other site
701347006564	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347006565	nucleotide binding region [chemical binding]; other site
701347006566	ATP-binding site [chemical binding]; other site
701347006567	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
701347006568	putative RNA binding site [nucleotide binding]; other site
701347006569	HutD; Region: HutD; pfam05962
701347006570	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
701347006571	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347006572	substrate binding pocket [chemical binding]; other site
701347006573	membrane-bound complex binding site; other site
701347006574	hinge residues; other site
701347006575	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347006576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006577	dimer interface [polypeptide binding]; other site
701347006578	conserved gate region; other site
701347006579	putative PBP binding loops; other site
701347006580	ABC-ATPase subunit interface; other site
701347006581	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347006582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006583	dimer interface [polypeptide binding]; other site
701347006584	conserved gate region; other site
701347006585	putative PBP binding loops; other site
701347006586	ABC-ATPase subunit interface; other site
701347006587	ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598
701347006588	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347006589	Walker A/P-loop; other site
701347006590	ATP binding site [chemical binding]; other site
701347006591	Q-loop/lid; other site
701347006592	ABC transporter signature motif; other site
701347006593	Walker B; other site
701347006594	D-loop; other site
701347006595	H-loop/switch region; other site
701347006596	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
701347006597	active sites [active]
701347006598	tetramer interface [polypeptide binding]; other site
701347006599	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
701347006600	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
701347006601	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
701347006602	Autotransporter beta-domain; Region: Autotransporter; pfam03797
701347006603	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
701347006604	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
701347006605	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
701347006606	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
701347006607	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
701347006608	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
701347006609	conserved cys residue [active]
701347006610	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347006611	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
701347006612	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347006613	dimerization interface [polypeptide binding]; other site
701347006614	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347006615	dimer interface [polypeptide binding]; other site
701347006616	phosphorylation site [posttranslational modification]
701347006617	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347006618	ATP binding site [chemical binding]; other site
701347006619	Mg2+ binding site [ion binding]; other site
701347006620	G-X-G motif; other site
701347006621	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
701347006622	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347006623	active site
701347006624	phosphorylation site [posttranslational modification]
701347006625	intermolecular recognition site; other site
701347006626	dimerization interface [polypeptide binding]; other site
701347006627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347006628	DNA binding site [nucleotide binding]
701347006629	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
701347006630	Protein export membrane protein; Region: SecD_SecF; cl14618
701347006631	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
701347006632	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347006633	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
701347006634	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
701347006635	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
701347006636	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
701347006637	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
701347006638	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347006639	catalytic residue [active]
701347006640	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
701347006641	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
701347006642	tetramer interface [polypeptide binding]; other site
701347006643	active site
701347006644	MmgE/PrpD family; Region: MmgE_PrpD; cl00912
701347006645	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
701347006646	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347006647	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
701347006648	putative dimerization interface [polypeptide binding]; other site
701347006649	Helix-Turn-Helix DNA binding domain of the transcription regulators NolA and AlbR; Region: HTH_NolA-AlbR; cd04788
701347006650	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
701347006651	DNA binding residues [nucleotide binding]
701347006652	putative dimer interface [polypeptide binding]; other site
701347006653	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
701347006654	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
701347006655	Autoinducer synthetase; Region: Autoind_synth; cl17404
701347006656	transcriptional regulator TraR; Provisional; Region: PRK13870
701347006657	Autoinducer binding domain; Region: Autoind_bind; pfam03472
701347006658	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347006659	DNA binding residues [nucleotide binding]
701347006660	dimerization interface [polypeptide binding]; other site
701347006661	GTP-binding protein YchF; Reviewed; Region: PRK09601
701347006662	YchF GTPase; Region: YchF; cd01900
701347006663	G1 box; other site
701347006664	GTP/Mg2+ binding site [chemical binding]; other site
701347006665	Switch I region; other site
701347006666	G2 box; other site
701347006667	Switch II region; other site
701347006668	G3 box; other site
701347006669	G4 box; other site
701347006670	G5 box; other site
701347006671	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
701347006672	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
701347006673	putative active site [active]
701347006674	catalytic residue [active]
701347006675	hypothetical protein; Provisional; Region: PRK10692
701347006676	putative transporter; Provisional; Region: PRK11660
701347006677	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
701347006678	Sulfate transporter family; Region: Sulfate_transp; pfam00916
701347006679	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
701347006680	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
701347006681	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
701347006682	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347006683	active site
701347006684	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
701347006685	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
701347006686	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
701347006687	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
701347006688	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
701347006689	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
701347006690	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
701347006691	tRNA; other site
701347006692	putative tRNA binding site [nucleotide binding]; other site
701347006693	putative NADP binding site [chemical binding]; other site
701347006694	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
701347006695	peptide chain release factor 1; Validated; Region: prfA; PRK00591
701347006696	This domain is found in peptide chain release factors; Region: PCRF; smart00937
701347006697	RF-1 domain; Region: RF-1; pfam00472
701347006698	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
701347006699	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
701347006700	hypothetical protein; Provisional; Region: PRK10941
701347006701	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
701347006702	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
701347006703	binding surface
701347006704	TPR motif; other site
701347006705	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
701347006706	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
701347006707	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
701347006708	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
701347006709	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
701347006710	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
701347006711	putative active site pocket [active]
701347006712	dimerization interface [polypeptide binding]; other site
701347006713	putative catalytic residue [active]
701347006714	Domain of unknown function (DUF1883); Region: DUF1883; pfam08980
701347006715	Cache domain; Region: Cache_1; pfam02743
701347006716	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347006717	dimerization interface [polypeptide binding]; other site
701347006718	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347006719	dimer interface [polypeptide binding]; other site
701347006720	putative CheW interface [polypeptide binding]; other site
701347006721	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
701347006722	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
701347006723	substrate binding site [chemical binding]; other site
701347006724	transcriptional regulator NarL; Provisional; Region: PRK10651
701347006725	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347006726	active site
701347006727	phosphorylation site [posttranslational modification]
701347006728	intermolecular recognition site; other site
701347006729	dimerization interface [polypeptide binding]; other site
701347006730	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347006731	DNA binding residues [nucleotide binding]
701347006732	dimerization interface [polypeptide binding]; other site
701347006733	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
701347006734	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
701347006735	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347006736	dimerization interface [polypeptide binding]; other site
701347006737	Histidine kinase; Region: HisKA_3; pfam07730
701347006738	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347006739	ATP binding site [chemical binding]; other site
701347006740	Mg2+ binding site [ion binding]; other site
701347006741	G-X-G motif; other site
701347006742	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
701347006743	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
701347006744	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
701347006745	[4Fe-4S] binding site [ion binding]; other site
701347006746	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347006747	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347006748	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347006749	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
701347006750	molybdopterin cofactor binding site; other site
701347006751	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
701347006752	4Fe-4S binding domain; Region: Fer4; cl02805
701347006753	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
701347006754	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
701347006755	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
701347006756	EamA-like transporter family; Region: EamA; pfam00892
701347006757	EamA-like transporter family; Region: EamA; pfam00892
701347006758	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
701347006759	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
701347006760	AsnC family; Region: AsnC_trans_reg; pfam01037
701347006761	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
701347006762	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
701347006763	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
701347006764	putative active site [active]
701347006765	putative substrate binding site [chemical binding]; other site
701347006766	putative cosubstrate binding site; other site
701347006767	catalytic site [active]
701347006768	hypothetical protein; Provisional; Region: PRK01617
701347006769	SEC-C motif; Region: SEC-C; pfam02810
701347006770	hypothetical protein; Provisional; Region: PRK10279
701347006771	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
701347006772	nucleophile elbow; other site
701347006773	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347006774	active site
701347006775	response regulator of RpoS; Provisional; Region: PRK10693
701347006776	phosphorylation site [posttranslational modification]
701347006777	intermolecular recognition site; other site
701347006778	dimerization interface [polypeptide binding]; other site
701347006779	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
701347006780	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
701347006781	active site
701347006782	tetramer interface; other site
701347006783	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
701347006784	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
701347006785	thymidine kinase; Provisional; Region: PRK04296
701347006786	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
701347006787	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
701347006788	putative catalytic cysteine [active]
701347006789	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
701347006790	putative active site [active]
701347006791	metal binding site [ion binding]; metal-binding site
701347006792	hypothetical protein; Provisional; Region: PRK11111
701347006793	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
701347006794	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
701347006795	peptide binding site [polypeptide binding]; other site
701347006796	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
701347006797	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006798	dimer interface [polypeptide binding]; other site
701347006799	conserved gate region; other site
701347006800	putative PBP binding loops; other site
701347006801	ABC-ATPase subunit interface; other site
701347006802	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
701347006803	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
701347006804	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347006805	dimer interface [polypeptide binding]; other site
701347006806	conserved gate region; other site
701347006807	ABC-ATPase subunit interface; other site
701347006808	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
701347006809	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347006810	Walker A/P-loop; other site
701347006811	ATP binding site [chemical binding]; other site
701347006812	Q-loop/lid; other site
701347006813	ABC transporter signature motif; other site
701347006814	Walker B; other site
701347006815	D-loop; other site
701347006816	H-loop/switch region; other site
701347006817	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
701347006818	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
701347006819	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347006820	Walker A/P-loop; other site
701347006821	ATP binding site [chemical binding]; other site
701347006822	Q-loop/lid; other site
701347006823	ABC transporter signature motif; other site
701347006824	Walker B; other site
701347006825	D-loop; other site
701347006826	H-loop/switch region; other site
701347006827	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
701347006828	Ion transport protein; Region: Ion_trans; pfam00520
701347006829	Ion channel; Region: Ion_trans_2; pfam07885
701347006830	Double zinc ribbon; Region: DZR; pfam12773
701347006831	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
701347006832	dsDNA-mimic protein; Reviewed; Region: PRK05094
701347006833	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
701347006834	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
701347006835	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
701347006836	putative active site [active]
701347006837	catalytic site [active]
701347006838	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
701347006839	putative active site [active]
701347006840	catalytic site [active]
701347006841	YciI-like protein; Reviewed; Region: PRK11370
701347006842	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
701347006843	Phosphotransferase enzyme family; Region: APH; pfam01636
701347006844	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
701347006845	active site
701347006846	ATP binding site [chemical binding]; other site
701347006847	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
701347006848	active site
701347006849	ATP binding site [chemical binding]; other site
701347006850	6-phosphofructokinase 2; Provisional; Region: PRK10294
701347006851	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
701347006852	putative substrate binding site [chemical binding]; other site
701347006853	putative ATP binding site [chemical binding]; other site
701347006854	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
701347006855	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
701347006856	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
701347006857	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
701347006858	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
701347006859	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
701347006860	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
701347006861	active site
701347006862	dimer interface [polypeptide binding]; other site
701347006863	motif 1; other site
701347006864	motif 2; other site
701347006865	motif 3; other site
701347006866	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
701347006867	anticodon binding site; other site
701347006868	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
701347006869	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
701347006870	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
701347006871	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
701347006872	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
701347006873	23S rRNA binding site [nucleotide binding]; other site
701347006874	L21 binding site [polypeptide binding]; other site
701347006875	L13 binding site [polypeptide binding]; other site
701347006876	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
701347006877	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
701347006878	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
701347006879	dimer interface [polypeptide binding]; other site
701347006880	motif 1; other site
701347006881	active site
701347006882	motif 2; other site
701347006883	motif 3; other site
701347006884	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
701347006885	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
701347006886	putative tRNA-binding site [nucleotide binding]; other site
701347006887	B3/4 domain; Region: B3_4; pfam03483
701347006888	tRNA synthetase B5 domain; Region: B5; smart00874
701347006889	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
701347006890	dimer interface [polypeptide binding]; other site
701347006891	motif 1; other site
701347006892	motif 3; other site
701347006893	motif 2; other site
701347006894	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
701347006895	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
701347006896	IHF dimer interface [polypeptide binding]; other site
701347006897	IHF - DNA interface [nucleotide binding]; other site
701347006898	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347006899	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347006900	ABC-ATPase subunit  interface; other site
701347006901	dimer interface [polypeptide binding]; other site
701347006902	putative PBP binding regions; other site
701347006903	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
701347006904	catalytic residues [active]
701347006905	dimer interface [polypeptide binding]; other site
701347006906	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
701347006907	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
701347006908	Walker A/P-loop; other site
701347006909	ATP binding site [chemical binding]; other site
701347006910	Q-loop/lid; other site
701347006911	ABC transporter signature motif; other site
701347006912	Walker B; other site
701347006913	D-loop; other site
701347006914	H-loop/switch region; other site
701347006915	NlpC/P60 family; Region: NLPC_P60; pfam00877
701347006916	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
701347006917	Uncharacterized conserved protein [Function unknown]; Region: COG0397
701347006918	hypothetical protein; Validated; Region: PRK00029
701347006919	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
701347006920	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
701347006921	Walker A/P-loop; other site
701347006922	ATP binding site [chemical binding]; other site
701347006923	Q-loop/lid; other site
701347006924	ABC transporter signature motif; other site
701347006925	Walker B; other site
701347006926	D-loop; other site
701347006927	H-loop/switch region; other site
701347006928	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347006929	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347006930	ABC-ATPase subunit  interface; other site
701347006931	dimer interface [polypeptide binding]; other site
701347006932	putative PBP binding regions; other site
701347006933	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
701347006934	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
701347006935	putative hemin binding site; other site
701347006936	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
701347006937	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
701347006938	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
701347006939	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
701347006940	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347006941	N-terminal plug; other site
701347006942	ligand-binding site [chemical binding]; other site
701347006943	Hemin uptake protein hemP; Region: hemP; cl10043
701347006944	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
701347006945	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
701347006946	PEP synthetase regulatory protein; Provisional; Region: PRK05339
701347006947	phosphoenolpyruvate synthase; Validated; Region: PRK06464
701347006948	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
701347006949	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
701347006950	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
701347006951	putative inner membrane protein; Provisional; Region: PRK10983
701347006952	Domain of unknown function DUF20; Region: UPF0118; pfam01594
701347006953	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
701347006954	FAD binding domain; Region: FAD_binding_4; pfam01565
701347006955	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
701347006956	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
701347006957	CoenzymeA binding site [chemical binding]; other site
701347006958	subunit interaction site [polypeptide binding]; other site
701347006959	PHB binding site; other site
701347006960	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
701347006961	CPxP  motif; other site
701347006962	putative inner membrane protein; Provisional; Region: PRK11099
701347006963	Sulphur transport; Region: Sulf_transp; pfam04143
701347006964	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
701347006965	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
701347006966	putative acyl-acceptor binding pocket; other site
701347006967	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
701347006968	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
701347006969	Catalytic site [active]
701347006970	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
701347006971	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
701347006972	active site
701347006973	DNA binding site [nucleotide binding]
701347006974	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
701347006975	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
701347006976	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
701347006977	putative ABC transporter; Region: ycf24; CHL00085
701347006978	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
701347006979	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
701347006980	Walker A/P-loop; other site
701347006981	ATP binding site [chemical binding]; other site
701347006982	Q-loop/lid; other site
701347006983	ABC transporter signature motif; other site
701347006984	Walker B; other site
701347006985	D-loop; other site
701347006986	H-loop/switch region; other site
701347006987	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
701347006988	FeS assembly protein SufD; Region: sufD; TIGR01981
701347006989	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
701347006990	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
701347006991	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347006992	catalytic residue [active]
701347006993	cysteine desufuration protein SufE; Provisional; Region: PRK09296
701347006994	L,D-transpeptidase; Provisional; Region: PRK10190
701347006995	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347006996	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347006997	murein lipoprotein; Provisional; Region: PRK15396
701347006998	pyruvate kinase; Provisional; Region: PRK09206
701347006999	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
701347007000	domain interfaces; other site
701347007001	active site
701347007002	hypothetical protein; Provisional; Region: PRK10292
701347007003	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
701347007004	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
701347007005	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
701347007006	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
701347007007	Walker A/P-loop; other site
701347007008	ATP binding site [chemical binding]; other site
701347007009	Q-loop/lid; other site
701347007010	ABC transporter signature motif; other site
701347007011	Walker B; other site
701347007012	D-loop; other site
701347007013	H-loop/switch region; other site
701347007014	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347007015	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347007016	ABC-ATPase subunit  interface; other site
701347007017	dimer interface [polypeptide binding]; other site
701347007018	putative PBP binding regions; other site
701347007019	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
701347007020	putative ligand binding residues [chemical binding]; other site
701347007021	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
701347007022	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
701347007023	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347007024	N-terminal plug; other site
701347007025	ligand-binding site [chemical binding]; other site
701347007026	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
701347007027	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
701347007028	Walker A/P-loop; other site
701347007029	ATP binding site [chemical binding]; other site
701347007030	Q-loop/lid; other site
701347007031	ABC transporter signature motif; other site
701347007032	Walker B; other site
701347007033	D-loop; other site
701347007034	H-loop/switch region; other site
701347007035	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347007036	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347007037	ABC-ATPase subunit  interface; other site
701347007038	dimer interface [polypeptide binding]; other site
701347007039	putative PBP binding regions; other site
701347007040	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347007041	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347007042	ABC-ATPase subunit  interface; other site
701347007043	dimer interface [polypeptide binding]; other site
701347007044	putative PBP binding regions; other site
701347007045	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
701347007046	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
701347007047	intersubunit interface [polypeptide binding]; other site
701347007048	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347007049	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347007050	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cd04795
701347007051	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
701347007052	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347007053	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
701347007054	substrate binding pocket [chemical binding]; other site
701347007055	membrane-bound complex binding site; other site
701347007056	hinge residues; other site
701347007057	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347007058	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347007059	dimer interface [polypeptide binding]; other site
701347007060	conserved gate region; other site
701347007061	putative PBP binding loops; other site
701347007062	ABC-ATPase subunit interface; other site
701347007063	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
701347007064	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347007065	Walker A/P-loop; other site
701347007066	ATP binding site [chemical binding]; other site
701347007067	Q-loop/lid; other site
701347007068	ABC transporter signature motif; other site
701347007069	Walker B; other site
701347007070	D-loop; other site
701347007071	H-loop/switch region; other site
701347007072	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
701347007073	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
701347007074	DNA binding residues [nucleotide binding]
701347007075	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347007076	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347007077	DNA binding residues [nucleotide binding]
701347007078	dimerization interface [polypeptide binding]; other site
701347007079	tetrathionate reductase subunit A; Provisional; Region: PRK14991
701347007080	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007081	molybdopterin cofactor binding site; other site
701347007082	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
701347007083	putative molybdopterin cofactor binding site [chemical binding]; other site
701347007084	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
701347007085	putative molybdopterin cofactor binding site; other site
701347007086	tetrathionate reductase subunit C; Provisional; Region: PRK14992
701347007087	tetrathionate reductase subunit B; Provisional; Region: PRK14993
701347007088	4Fe-4S binding domain; Region: Fer4; pfam00037
701347007089	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
701347007090	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347007091	dimer interface [polypeptide binding]; other site
701347007092	phosphorylation site [posttranslational modification]
701347007093	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347007094	ATP binding site [chemical binding]; other site
701347007095	G-X-G motif; other site
701347007096	Response regulator receiver domain; Region: Response_reg; pfam00072
701347007097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347007098	active site
701347007099	phosphorylation site [posttranslational modification]
701347007100	intermolecular recognition site; other site
701347007101	dimerization interface [polypeptide binding]; other site
701347007102	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347007103	DNA binding residues [nucleotide binding]
701347007104	Transposase IS200 like; Region: Y1_Tnp; pfam01797
701347007105	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
701347007106	Fimbrial protein; Region: Fimbrial; cl01416
701347007107	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347007108	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
701347007109	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347007110	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347007111	PapC N-terminal domain; Region: PapC_N; pfam13954
701347007112	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347007113	PapC C-terminal domain; Region: PapC_C; pfam13953
701347007114	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347007115	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347007116	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
701347007117	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347007118	DNA binding residues [nucleotide binding]
701347007119	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
701347007120	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347007121	PAS domain; Region: PAS_9; pfam13426
701347007122	putative active site [active]
701347007123	heme pocket [chemical binding]; other site
701347007124	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347007125	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347007126	metal binding site [ion binding]; metal-binding site
701347007127	active site
701347007128	I-site; other site
701347007129	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347007130	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
701347007131	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
701347007132	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
701347007133	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
701347007134	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
701347007135	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
701347007136	maltose O-acetyltransferase; Provisional; Region: PRK10092
701347007137	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
701347007138	active site
701347007139	substrate binding site [chemical binding]; other site
701347007140	trimer interface [polypeptide binding]; other site
701347007141	CoA binding site [chemical binding]; other site
701347007142	multidrug efflux protein; Reviewed; Region: PRK01766
701347007143	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
701347007144	cation binding site [ion binding]; other site
701347007145	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
701347007146	Lumazine binding domain; Region: Lum_binding; pfam00677
701347007147	Lumazine binding domain; Region: Lum_binding; pfam00677
701347007148	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
701347007149	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
701347007150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347007151	S-adenosylmethionine binding site [chemical binding]; other site
701347007152	putative transporter; Provisional; Region: PRK11043
701347007153	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007154	putative substrate translocation pore; other site
701347007155	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
701347007156	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007157	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347007158	dimerization interface [polypeptide binding]; other site
701347007159	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
701347007160	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347007161	DNA binding site [nucleotide binding]
701347007162	domain linker motif; other site
701347007163	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
701347007164	dimerization interface [polypeptide binding]; other site
701347007165	ligand binding site [chemical binding]; other site
701347007166	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007167	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347007168	putative substrate translocation pore; other site
701347007169	superoxide dismutase; Provisional; Region: PRK10543
701347007170	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
701347007171	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
701347007172	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
701347007173	NlpC/P60 family; Region: NLPC_P60; pfam00877
701347007174	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
701347007175	putative GSH binding site [chemical binding]; other site
701347007176	catalytic residues [active]
701347007177	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
701347007178	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
701347007179	dimer interface [polypeptide binding]; other site
701347007180	catalytic site [active]
701347007181	putative active site [active]
701347007182	putative substrate binding site [chemical binding]; other site
701347007183	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
701347007184	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
701347007185	dimer interface [polypeptide binding]; other site
701347007186	active site
701347007187	metal binding site [ion binding]; metal-binding site
701347007188	glutathione binding site [chemical binding]; other site
701347007189	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
701347007190	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
701347007191	FMN binding site [chemical binding]; other site
701347007192	active site
701347007193	substrate binding site [chemical binding]; other site
701347007194	catalytic residue [active]
701347007195	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
701347007196	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347007197	Predicted Fe-S protein [General function prediction only]; Region: COG3313
701347007198	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347007199	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347007200	active site
701347007201	catalytic tetrad [active]
701347007202	Fusaric acid resistance protein family; Region: FUSC; pfam04632
701347007203	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
701347007204	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
701347007205	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347007206	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347007207	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
701347007208	transcriptional regulator SlyA; Provisional; Region: PRK03573
701347007209	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
701347007210	xanthine permease; Region: pbuX; TIGR03173
701347007211	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347007212	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347007213	metal binding site [ion binding]; metal-binding site
701347007214	active site
701347007215	I-site; other site
701347007216	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
701347007217	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
701347007218	lysozyme inhibitor; Provisional; Region: PRK11372
701347007219	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
701347007220	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
701347007221	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
701347007222	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
701347007223	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
701347007224	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
701347007225	active site
701347007226	HIGH motif; other site
701347007227	dimer interface [polypeptide binding]; other site
701347007228	KMSKS motif; other site
701347007229	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347007230	RNA binding surface [nucleotide binding]; other site
701347007231	pyridoxamine kinase; Validated; Region: PRK05756
701347007232	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
701347007233	dimer interface [polypeptide binding]; other site
701347007234	pyridoxal binding site [chemical binding]; other site
701347007235	ATP binding site [chemical binding]; other site
701347007236	glutathionine S-transferase; Provisional; Region: PRK10542
701347007237	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
701347007238	C-terminal domain interface [polypeptide binding]; other site
701347007239	GSH binding site (G-site) [chemical binding]; other site
701347007240	dimer interface [polypeptide binding]; other site
701347007241	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
701347007242	N-terminal domain interface [polypeptide binding]; other site
701347007243	dimer interface [polypeptide binding]; other site
701347007244	substrate binding pocket (H-site) [chemical binding]; other site
701347007245	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
701347007246	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007247	putative substrate translocation pore; other site
701347007248	POT family; Region: PTR2; pfam00854
701347007249	endonuclease III; Provisional; Region: PRK10702
701347007250	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
701347007251	minor groove reading motif; other site
701347007252	helix-hairpin-helix signature motif; other site
701347007253	substrate binding pocket [chemical binding]; other site
701347007254	active site
701347007255	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
701347007256	electron transport complex RsxE subunit; Provisional; Region: PRK12405
701347007257	electron transport complex protein RnfG; Validated; Region: PRK01908
701347007258	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
701347007259	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
701347007260	SLBB domain; Region: SLBB; pfam10531
701347007261	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347007262	electron transport complex protein RnfB; Provisional; Region: PRK05113
701347007263	Putative Fe-S cluster; Region: FeS; pfam04060
701347007264	4Fe-4S binding domain; Region: Fer4; cl02805
701347007265	electron transport complex protein RsxA; Provisional; Region: PRK05151
701347007266	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
701347007267	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
701347007268	putative oxidoreductase; Provisional; Region: PRK11579
701347007269	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347007270	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
701347007271	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
701347007272	adenosine deaminase; Provisional; Region: PRK09358
701347007273	active site
701347007274	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
701347007275	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347007276	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347007277	homodimer interface [polypeptide binding]; other site
701347007278	catalytic residue [active]
701347007279	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
701347007280	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
701347007281	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347007282	active site turn [active]
701347007283	phosphorylation site [posttranslational modification]
701347007284	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
701347007285	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347007286	DNA binding site [nucleotide binding]
701347007287	domain linker motif; other site
701347007288	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
701347007289	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
701347007290	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
701347007291	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
701347007292	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
701347007293	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
701347007294	fumarate hydratase; Provisional; Region: PRK15389
701347007295	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
701347007296	Fumarase C-terminus; Region: Fumerase_C; pfam05683
701347007297	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
701347007298	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
701347007299	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
701347007300	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347007301	dimerization interface [polypeptide binding]; other site
701347007302	putative DNA binding site [nucleotide binding]; other site
701347007303	putative Zn2+ binding site [ion binding]; other site
701347007304	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
701347007305	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
701347007306	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
701347007307	P loop; other site
701347007308	Nucleotide binding site [chemical binding]; other site
701347007309	DTAP/Switch II; other site
701347007310	Switch I; other site
701347007311	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
701347007312	P loop; other site
701347007313	Nucleotide binding site [chemical binding]; other site
701347007314	DTAP/Switch II; other site
701347007315	Switch I; other site
701347007316	arsenical pump membrane protein; Provisional; Region: PRK15445
701347007317	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
701347007318	transmembrane helices; other site
701347007319	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
701347007320	ArsC family; Region: ArsC; pfam03960
701347007321	catalytic residues [active]
701347007322	cytochrome b561; Provisional; Region: PRK11513
701347007323	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
701347007324	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007325	The C-terminal substrate binding domain of galactose-binding protein regulator contains the type 2 periplasmic binding fold; Region: PBP2_GbpR; cd08435
701347007326	putative dimerization interface [polypeptide binding]; other site
701347007327	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
701347007328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
701347007329	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
701347007330	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
701347007331	substrate binding pocket [chemical binding]; other site
701347007332	catalytic triad [active]
701347007333	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
701347007334	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007335	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347007336	dimerization interface [polypeptide binding]; other site
701347007337	putative aminotransferase; Provisional; Region: PRK12414
701347007338	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347007339	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347007340	homodimer interface [polypeptide binding]; other site
701347007341	catalytic residue [active]
701347007342	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
701347007343	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347007344	substrate binding pocket [chemical binding]; other site
701347007345	membrane-bound complex binding site; other site
701347007346	hinge residues; other site
701347007347	PAS domain S-box; Region: sensory_box; TIGR00229
701347007348	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347007349	putative active site [active]
701347007350	heme pocket [chemical binding]; other site
701347007351	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347007352	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347007353	metal binding site [ion binding]; metal-binding site
701347007354	active site
701347007355	I-site; other site
701347007356	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
701347007357	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
701347007358	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
701347007359	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
701347007360	S-adenosylmethionine binding site [chemical binding]; other site
701347007361	Uncharacterized conserved protein [Function unknown]; Region: COG1434
701347007362	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
701347007363	putative active site [active]
701347007364	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
701347007365	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
701347007366	NAD binding site [chemical binding]; other site
701347007367	catalytic residues [active]
701347007368	substrate binding site [chemical binding]; other site
701347007369	fumarate hydratase; Reviewed; Region: fumC; PRK00485
701347007370	Class II fumarases; Region: Fumarase_classII; cd01362
701347007371	active site
701347007372	tetramer interface [polypeptide binding]; other site
701347007373	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
701347007374	sensor protein RstB; Provisional; Region: PRK10604
701347007375	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347007376	dimerization interface [polypeptide binding]; other site
701347007377	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347007378	dimer interface [polypeptide binding]; other site
701347007379	phosphorylation site [posttranslational modification]
701347007380	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347007381	ATP binding site [chemical binding]; other site
701347007382	Mg2+ binding site [ion binding]; other site
701347007383	G-X-G motif; other site
701347007384	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
701347007385	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347007386	active site
701347007387	phosphorylation site [posttranslational modification]
701347007388	intermolecular recognition site; other site
701347007389	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347007390	DNA binding site [nucleotide binding]
701347007391	GlpM protein; Region: GlpM; pfam06942
701347007392	dihydromonapterin reductase; Provisional; Region: PRK06483
701347007393	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
701347007394	NADP binding site [chemical binding]; other site
701347007395	substrate binding pocket [chemical binding]; other site
701347007396	active site
701347007397	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
701347007398	Spore germination protein; Region: Spore_permease; cl17796
701347007399	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347007400	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347007401	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347007402	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
701347007403	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
701347007404	ligand binding site [chemical binding]; other site
701347007405	homodimer interface [polypeptide binding]; other site
701347007406	NAD(P) binding site [chemical binding]; other site
701347007407	trimer interface B [polypeptide binding]; other site
701347007408	trimer interface A [polypeptide binding]; other site
701347007409	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
701347007410	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
701347007411	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
701347007412	leucine export protein LeuE; Provisional; Region: PRK10958
701347007413	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
701347007414	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
701347007415	substrate binding site [chemical binding]; other site
701347007416	catalytic Zn binding site [ion binding]; other site
701347007417	NAD binding site [chemical binding]; other site
701347007418	structural Zn binding site [ion binding]; other site
701347007419	dimer interface [polypeptide binding]; other site
701347007420	methyl-accepting protein IV; Provisional; Region: PRK09793
701347007421	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
701347007422	dimer interface [polypeptide binding]; other site
701347007423	ligand binding site [chemical binding]; other site
701347007424	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347007425	dimerization interface [polypeptide binding]; other site
701347007426	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347007427	dimer interface [polypeptide binding]; other site
701347007428	putative CheW interface [polypeptide binding]; other site
701347007429	universal stress protein UspE; Provisional; Region: PRK11175
701347007430	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347007431	Ligand Binding Site [chemical binding]; other site
701347007432	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347007433	Ligand Binding Site [chemical binding]; other site
701347007434	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
701347007435	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
701347007436	ligand binding site [chemical binding]; other site
701347007437	flexible hinge region; other site
701347007438	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
701347007439	putative switch regulator; other site
701347007440	non-specific DNA interactions [nucleotide binding]; other site
701347007441	DNA binding site [nucleotide binding]
701347007442	sequence specific DNA binding site [nucleotide binding]; other site
701347007443	putative cAMP binding site [chemical binding]; other site
701347007444	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
701347007445	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
701347007446	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
701347007447	DNA binding site [nucleotide binding]
701347007448	active site
701347007449	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
701347007450	Smr domain; Region: Smr; pfam01713
701347007451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007452	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
701347007453	putative substrate translocation pore; other site
701347007454	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
701347007455	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
701347007456	Domain of unknown function DUF20; Region: UPF0118; pfam01594
701347007457	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
701347007458	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
701347007459	CHASE4 domain; Region: CHASE4; pfam05228
701347007460	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347007461	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347007462	metal binding site [ion binding]; metal-binding site
701347007463	active site
701347007464	I-site; other site
701347007465	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347007466	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
701347007467	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
701347007468	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
701347007469	active site
701347007470	Zn binding site [ion binding]; other site
701347007471	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
701347007472	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
701347007473	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
701347007474	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
701347007475	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
701347007476	EAL domain; Region: EAL; pfam00563
701347007477	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
701347007478	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
701347007479	active site
701347007480	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347007481	S-adenosylmethionine binding site [chemical binding]; other site
701347007482	phage assembly protein; Region: IV; PHA00019
701347007483	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
701347007484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007485	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347007486	putative substrate translocation pore; other site
701347007487	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
701347007488	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347007489	Predicted membrane protein [Function unknown]; Region: COG4125
701347007490	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
701347007491	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
701347007492	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347007493	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007494	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
701347007495	dimerization interface [polypeptide binding]; other site
701347007496	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347007497	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347007498	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347007499	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347007500	PapC C-terminal domain; Region: PapC_C; pfam13953
701347007501	Spore Coat Protein U domain; Region: SCPU; pfam05229
701347007502	Uncharacterized secreted protein [Function unknown]; Region: COG5430
701347007503	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
701347007504	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
701347007505	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
701347007506	NAD(P) binding site [chemical binding]; other site
701347007507	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
701347007508	phosphonate metabolim protein, transferase hexapeptide repeat family; Region: phn_thr-fam; TIGR03308
701347007509	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
701347007510	trimer interface [polypeptide binding]; other site
701347007511	active site
701347007512	substrate binding site [chemical binding]; other site
701347007513	CoA binding site [chemical binding]; other site
701347007514	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
701347007515	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347007516	S-adenosylmethionine binding site [chemical binding]; other site
701347007517	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347007518	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
701347007519	Coenzyme A binding pocket [chemical binding]; other site
701347007520	Predicted membrane protein [Function unknown]; Region: COG3781
701347007521	altronate oxidoreductase; Provisional; Region: PRK03643
701347007522	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
701347007523	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
701347007524	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347007525	Coenzyme A binding pocket [chemical binding]; other site
701347007526	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
701347007527	glutaminase; Provisional; Region: PRK00971
701347007528	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
701347007529	dimer interface [polypeptide binding]; other site
701347007530	ligand binding site [chemical binding]; other site
701347007531	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347007532	dimerization interface [polypeptide binding]; other site
701347007533	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347007534	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347007535	dimer interface [polypeptide binding]; other site
701347007536	putative CheW interface [polypeptide binding]; other site
701347007537	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
701347007538	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
701347007539	NAD(P) binding site [chemical binding]; other site
701347007540	catalytic residues [active]
701347007541	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347007542	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007543	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
701347007544	putative dimerization interface [polypeptide binding]; other site
701347007545	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
701347007546	putative arabinose transporter; Provisional; Region: PRK03545
701347007547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007548	putative substrate translocation pore; other site
701347007549	inner membrane protein; Provisional; Region: PRK10995
701347007550	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
701347007551	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
701347007552	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
701347007553	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347007554	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347007555	MarB protein; Region: MarB; pfam13999
701347007556	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
701347007557	EamA-like transporter family; Region: EamA; cl17759
701347007558	EamA-like transporter family; Region: EamA; pfam00892
701347007559	putative transporter; Provisional; Region: PRK10054
701347007560	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007561	putative substrate translocation pore; other site
701347007562	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
701347007563	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
701347007564	ligand binding site [chemical binding]; other site
701347007565	flexible hinge region; other site
701347007566	Transcriptional regulator; Region: Rrf2; cl17282
701347007567	Uncharacterized conserved protein [Function unknown]; Region: COG5361
701347007568	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
701347007569	Uncharacterized conserved protein [Function unknown]; Region: COG5361
701347007570	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
701347007571	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
701347007572	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
701347007573	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
701347007574	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
701347007575	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
701347007576	active site
701347007577	Zn binding site [ion binding]; other site
701347007578	malonic semialdehyde reductase; Provisional; Region: PRK10538
701347007579	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
701347007580	putative NAD(P) binding site [chemical binding]; other site
701347007581	homodimer interface [polypeptide binding]; other site
701347007582	homotetramer interface [polypeptide binding]; other site
701347007583	active site
701347007584	Transcriptional regulators [Transcription]; Region: GntR; COG1802
701347007585	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347007586	DNA-binding site [nucleotide binding]; DNA binding site
701347007587	FCD domain; Region: FCD; pfam07729
701347007588	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347007589	Ligand Binding Site [chemical binding]; other site
701347007590	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
701347007591	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347007592	catalytic residue [active]
701347007593	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
701347007594	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
701347007595	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
701347007596	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
701347007597	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
701347007598	shikimate transporter; Provisional; Region: PRK09952
701347007599	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007600	putative substrate translocation pore; other site
701347007601	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007602	metabolite-proton symporter; Region: 2A0106; TIGR00883
701347007603	putative substrate translocation pore; other site
701347007604	putative oxidoreductase; Provisional; Region: PRK10083
701347007605	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
701347007606	putative NAD(P) binding site [chemical binding]; other site
701347007607	catalytic Zn binding site [ion binding]; other site
701347007608	structural Zn binding site [ion binding]; other site
701347007609	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
701347007610	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
701347007611	putative active site pocket [active]
701347007612	putative metal binding site [ion binding]; other site
701347007613	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
701347007614	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347007615	dimer interface [polypeptide binding]; other site
701347007616	conserved gate region; other site
701347007617	putative PBP binding loops; other site
701347007618	ABC-ATPase subunit interface; other site
701347007619	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347007620	dimer interface [polypeptide binding]; other site
701347007621	conserved gate region; other site
701347007622	putative PBP binding loops; other site
701347007623	ABC-ATPase subunit interface; other site
701347007624	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
701347007625	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
701347007626	Walker A/P-loop; other site
701347007627	ATP binding site [chemical binding]; other site
701347007628	Q-loop/lid; other site
701347007629	ABC transporter signature motif; other site
701347007630	Walker B; other site
701347007631	D-loop; other site
701347007632	H-loop/switch region; other site
701347007633	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
701347007634	hypothetical protein; Provisional; Region: PRK02237
701347007635	hypothetical protein; Provisional; Region: PRK13659
701347007636	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
701347007637	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347007638	Coenzyme A binding pocket [chemical binding]; other site
701347007639	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
701347007640	Uncharacterized protein family (UPF0257); Region: UPF0257; cl14672
701347007641	Hok/gef family; Region: HOK_GEF; pfam01848
701347007642	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
701347007643	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
701347007644	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
701347007645	putative [Fe4-S4] binding site [ion binding]; other site
701347007646	putative molybdopterin cofactor binding site [chemical binding]; other site
701347007647	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
701347007648	putative molybdopterin cofactor binding site; other site
701347007649	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
701347007650	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
701347007651	Cl- selectivity filter; other site
701347007652	Cl- binding residues [ion binding]; other site
701347007653	pore gating glutamate residue; other site
701347007654	dimer interface [polypeptide binding]; other site
701347007655	putative dithiobiotin synthetase; Provisional; Region: PRK12374
701347007656	AAA domain; Region: AAA_26; pfam13500
701347007657	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
701347007658	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
701347007659	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347007660	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
701347007661	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007662	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
701347007663	dimerization interface [polypeptide binding]; other site
701347007664	substrate binding pocket [chemical binding]; other site
701347007665	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
701347007666	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007667	putative substrate translocation pore; other site
701347007668	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
701347007669	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347007670	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347007671	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
701347007672	putative effector binding pocket; other site
701347007673	dimerization interface [polypeptide binding]; other site
701347007674	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
701347007675	30S ribosomal protein subunit S22 family; Region: Ribosomal_S22; cl11579
701347007676	malate dehydrogenase; Provisional; Region: PRK13529
701347007677	Malic enzyme, N-terminal domain; Region: malic; pfam00390
701347007678	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
701347007679	NAD(P) binding site [chemical binding]; other site
701347007680	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
701347007681	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347007682	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347007683	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
701347007684	CcdB protein; Region: CcdB; cl03380
701347007685	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
701347007686	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
701347007687	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
701347007688	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
701347007689	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007690	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007691	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
701347007692	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
701347007693	molybdopterin cofactor binding site; other site
701347007694	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007695	aromatic amino acid exporter; Provisional; Region: PRK11689
701347007696	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
701347007697	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347007698	putative substrate translocation pore; other site
701347007699	TetR family transcriptional regulator; Provisional; Region: PRK14996
701347007700	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
701347007701	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
701347007702	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
701347007703	[4Fe-4S] binding site [ion binding]; other site
701347007704	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007705	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007706	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347007707	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
701347007708	molybdopterin cofactor binding site; other site
701347007709	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
701347007710	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
701347007711	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
701347007712	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
701347007713	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
701347007714	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
701347007715	active site 1 [active]
701347007716	dimer interface [polypeptide binding]; other site
701347007717	hexamer interface [polypeptide binding]; other site
701347007718	active site 2 [active]
701347007719	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
701347007720	L-asparagine permease; Provisional; Region: PRK15049
701347007721	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
701347007722	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
701347007723	PQQ-like domain; Region: PQQ_2; pfam13360
701347007724	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
701347007725	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
701347007726	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
701347007727	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347007728	N-terminal plug; other site
701347007729	ligand-binding site [chemical binding]; other site
701347007730	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
701347007731	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347007732	DNA-binding site [nucleotide binding]; DNA binding site
701347007733	FCD domain; Region: FCD; pfam07729
701347007734	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347007735	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347007736	sequence-specific DNA binding site [nucleotide binding]; other site
701347007737	salt bridge; other site
701347007738	Cupin domain; Region: Cupin_2; pfam07883
701347007739	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
701347007740	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347007741	Coenzyme A binding pocket [chemical binding]; other site
701347007742	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
701347007743	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
701347007744	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
701347007745	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347007746	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
701347007747	peptide binding site [polypeptide binding]; other site
701347007748	Virulence factor SrfB; Region: SrfB; pfam07520
701347007749	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
701347007750	PGAP1-like protein; Region: PGAP1; pfam07819
701347007751	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
701347007752	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
701347007753	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
701347007754	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
701347007755	tetrameric interface [polypeptide binding]; other site
701347007756	NAD binding site [chemical binding]; other site
701347007757	catalytic residues [active]
701347007758	substrate binding site [chemical binding]; other site
701347007759	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
701347007760	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
701347007761	ABC-ATPase subunit interface; other site
701347007762	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347007763	dimer interface [polypeptide binding]; other site
701347007764	conserved gate region; other site
701347007765	putative PBP binding loops; other site
701347007766	ABC-ATPase subunit interface; other site
701347007767	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
701347007768	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347007769	Walker A/P-loop; other site
701347007770	ATP binding site [chemical binding]; other site
701347007771	Q-loop/lid; other site
701347007772	ABC transporter signature motif; other site
701347007773	Walker B; other site
701347007774	D-loop; other site
701347007775	H-loop/switch region; other site
701347007776	TOBE domain; Region: TOBE_2; pfam08402
701347007777	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
701347007778	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
701347007779	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
701347007780	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347007781	DNA-binding site [nucleotide binding]; DNA binding site
701347007782	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347007783	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347007784	homodimer interface [polypeptide binding]; other site
701347007785	catalytic residue [active]
701347007786	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
701347007787	aromatic amino acid transport protein; Region: araaP; TIGR00837
701347007788	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
701347007789	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
701347007790	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347007791	catalytic residue [active]
701347007792	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
701347007793	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
701347007794	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
701347007795	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
701347007796	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
701347007797	Peptidase family U32; Region: Peptidase_U32; pfam01136
701347007798	Collagenase; Region: DUF3656; pfam12392
701347007799	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347007800	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347007801	non-specific DNA binding site [nucleotide binding]; other site
701347007802	salt bridge; other site
701347007803	sequence-specific DNA binding site [nucleotide binding]; other site
701347007804	Cupin domain; Region: Cupin_2; pfam07883
701347007805	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
701347007806	benzoate transporter; Region: benE; TIGR00843
701347007807	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
701347007808	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347007809	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
701347007810	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
701347007811	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
701347007812	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347007813	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
701347007814	peptide binding site [polypeptide binding]; other site
701347007815	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
701347007816	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
701347007817	metal binding site [ion binding]; metal-binding site
701347007818	dimer interface [polypeptide binding]; other site
701347007819	tellurite resistance protein TehB; Provisional; Region: PRK11207
701347007820	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347007821	S-adenosylmethionine binding site [chemical binding]; other site
701347007822	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
701347007823	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
701347007824	gating phenylalanine in ion channel; other site
701347007825	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
701347007826	putative trimer interface [polypeptide binding]; other site
701347007827	putative CoA binding site [chemical binding]; other site
701347007828	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
701347007829	putative trimer interface [polypeptide binding]; other site
701347007830	putative CoA binding site [chemical binding]; other site
701347007831	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
701347007832	putative trimer interface [polypeptide binding]; other site
701347007833	putative CoA binding site [chemical binding]; other site
701347007834	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
701347007835	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347007836	ATP binding site [chemical binding]; other site
701347007837	putative Mg++ binding site [ion binding]; other site
701347007838	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347007839	nucleotide binding region [chemical binding]; other site
701347007840	ATP-binding site [chemical binding]; other site
701347007841	Helicase associated domain (HA2); Region: HA2; pfam04408
701347007842	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
701347007843	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
701347007844	azoreductase; Reviewed; Region: PRK00170
701347007845	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
701347007846	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
701347007847	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
701347007848	putative trimer interface [polypeptide binding]; other site
701347007849	putative metal binding site [ion binding]; other site
701347007850	PaaX-like protein; Region: PaaX; pfam07848
701347007851	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
701347007852	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
701347007853	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
701347007854	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
701347007855	active site
701347007856	AMP binding site [chemical binding]; other site
701347007857	homodimer interface [polypeptide binding]; other site
701347007858	acyl-activating enzyme (AAE) consensus motif; other site
701347007859	CoA binding site [chemical binding]; other site
701347007860	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
701347007861	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
701347007862	dimer interface [polypeptide binding]; other site
701347007863	active site
701347007864	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
701347007865	CoenzymeA binding site [chemical binding]; other site
701347007866	subunit interaction site [polypeptide binding]; other site
701347007867	PHB binding site; other site
701347007868	3-hydroxy-acyl-CoA dehydrogenase; Validated; Region: PRK08268
701347007869	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
701347007870	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
701347007871	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
701347007872	enoyl-CoA hydratase; Provisional; Region: PRK08140
701347007873	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347007874	substrate binding site [chemical binding]; other site
701347007875	oxyanion hole (OAH) forming residues; other site
701347007876	trimer interface [polypeptide binding]; other site
701347007877	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
701347007878	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347007879	substrate binding site [chemical binding]; other site
701347007880	oxyanion hole (OAH) forming residues; other site
701347007881	trimer interface [polypeptide binding]; other site
701347007882	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
701347007883	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
701347007884	FAD binding pocket [chemical binding]; other site
701347007885	FAD binding motif [chemical binding]; other site
701347007886	phosphate binding motif [ion binding]; other site
701347007887	beta-alpha-beta structure motif; other site
701347007888	NAD(p) ribose binding residues [chemical binding]; other site
701347007889	NAD binding pocket [chemical binding]; other site
701347007890	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
701347007891	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347007892	catalytic loop [active]
701347007893	iron binding site [ion binding]; other site
701347007894	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
701347007895	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
701347007896	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
701347007897	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
701347007898	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
701347007899	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
701347007900	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
701347007901	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
701347007902	substrate binding site [chemical binding]; other site
701347007903	dimer interface [polypeptide binding]; other site
701347007904	NADP binding site [chemical binding]; other site
701347007905	catalytic residues [active]
701347007906	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
701347007907	active site 2 [active]
701347007908	active site 1 [active]
701347007909	tyramine oxidase; Provisional; Region: tynA; PRK14696
701347007910	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
701347007911	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
701347007912	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
701347007913	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
701347007914	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
701347007915	2-enoyl thioester reductase-like; Region: ETR_like; cd05282
701347007916	NADP binding site [chemical binding]; other site
701347007917	dimer interface [polypeptide binding]; other site
701347007918	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
701347007919	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
701347007920	NAD(P) binding site [chemical binding]; other site
701347007921	catalytic residues [active]
701347007922	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
701347007923	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347007924	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
701347007925	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
701347007926	hypothetical protein; Provisional; Region: PRK10695
701347007927	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
701347007928	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
701347007929	putative ligand binding site [chemical binding]; other site
701347007930	putative NAD binding site [chemical binding]; other site
701347007931	catalytic site [active]
701347007932	META domain; Region: META; cl01245
701347007933	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
701347007934	Domain of unknown function (DUF333); Region: DUF333; pfam03891
701347007935	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347007936	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347007937	trimer interface [polypeptide binding]; other site
701347007938	eyelet of channel; other site
701347007939	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
701347007940	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
701347007941	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
701347007942	dimer interface [polypeptide binding]; other site
701347007943	PYR/PP interface [polypeptide binding]; other site
701347007944	TPP binding site [chemical binding]; other site
701347007945	substrate binding site [chemical binding]; other site
701347007946	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
701347007947	Domain of unknown function; Region: EKR; pfam10371
701347007948	4Fe-4S binding domain; Region: Fer4_6; pfam12837
701347007949	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347007950	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
701347007951	TPP-binding site [chemical binding]; other site
701347007952	dimer interface [polypeptide binding]; other site
701347007953	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347007954	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347007955	trimer interface [polypeptide binding]; other site
701347007956	eyelet of channel; other site
701347007957	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
701347007958	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
701347007959	Ligand Binding Site [chemical binding]; other site
701347007960	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
701347007961	Sulfatase; Region: Sulfatase; cl17466
701347007962	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
701347007963	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
701347007964	Cl binding site [ion binding]; other site
701347007965	oligomer interface [polypeptide binding]; other site
701347007966	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347007967	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347007968	metal binding site [ion binding]; metal-binding site
701347007969	active site
701347007970	I-site; other site
701347007971	HAMP domain; Region: HAMP; pfam00672
701347007972	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347007973	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347007974	dimer interface [polypeptide binding]; other site
701347007975	putative CheW interface [polypeptide binding]; other site
701347007976	PAS domain S-box; Region: sensory_box; TIGR00229
701347007977	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347007978	putative active site [active]
701347007979	heme pocket [chemical binding]; other site
701347007980	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347007981	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347007982	metal binding site [ion binding]; metal-binding site
701347007983	active site
701347007984	I-site; other site
701347007985	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
701347007986	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347007987	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
701347007988	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347007989	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347007990	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
701347007991	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
701347007992	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347007993	active site turn [active]
701347007994	phosphorylation site [posttranslational modification]
701347007995	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
701347007996	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347007997	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347007998	trimer interface [polypeptide binding]; other site
701347007999	eyelet of channel; other site
701347008000	intracellular protease, PfpI family; Region: PfpI; TIGR01382
701347008001	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
701347008002	conserved cys residue [active]
701347008003	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
701347008004	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
701347008005	peptide binding site [polypeptide binding]; other site
701347008006	murein peptide amidase A; Provisional; Region: PRK10602
701347008007	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
701347008008	active site
701347008009	Zn binding site [ion binding]; other site
701347008010	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
701347008011	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
701347008012	active site
701347008013	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
701347008014	dimer interface [polypeptide binding]; other site
701347008015	catalytic triad [active]
701347008016	peroxidatic and resolving cysteines [active]
701347008017	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
701347008018	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
701347008019	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
701347008020	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
701347008021	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
701347008022	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347008023	putative active site [active]
701347008024	heme pocket [chemical binding]; other site
701347008025	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347008026	Walker A motif; other site
701347008027	ATP binding site [chemical binding]; other site
701347008028	Walker B motif; other site
701347008029	arginine finger; other site
701347008030	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
701347008031	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
701347008032	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
701347008033	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
701347008034	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
701347008035	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
701347008036	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
701347008037	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
701347008038	nickel binding site [ion binding]; other site
701347008039	putative substrate-binding site; other site
701347008040	hydrogenase 2 large subunit; Provisional; Region: PRK10467
701347008041	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
701347008042	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
701347008043	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
701347008044	4Fe-4S binding domain; Region: Fer4; cl02805
701347008045	hydrogenase 2 small subunit; Provisional; Region: PRK10468
701347008046	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
701347008047	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
701347008048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347008049	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
701347008050	putative substrate translocation pore; other site
701347008051	ferredoxin-like protein FixX; Provisional; Region: PRK15449
701347008052	putative oxidoreductase FixC; Provisional; Region: PRK10157
701347008053	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
701347008054	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
701347008055	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
701347008056	Ligand binding site [chemical binding]; other site
701347008057	Electron transfer flavoprotein domain; Region: ETF; pfam01012
701347008058	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
701347008059	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
701347008060	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
701347008061	active site
701347008062	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
701347008063	CoA-transferase family III; Region: CoA_transf_3; pfam02515
701347008064	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
701347008065	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
701347008066	acyl-activating enzyme (AAE) consensus motif; other site
701347008067	putative AMP binding site [chemical binding]; other site
701347008068	putative active site [active]
701347008069	putative CoA binding site [chemical binding]; other site
701347008070	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
701347008071	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347008072	substrate binding site [chemical binding]; other site
701347008073	oxyanion hole (OAH) forming residues; other site
701347008074	trimer interface [polypeptide binding]; other site
701347008075	carnitine operon protein CaiE; Provisional; Region: PRK13627
701347008076	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
701347008077	putative trimer interface [polypeptide binding]; other site
701347008078	putative metal binding site [ion binding]; other site
701347008079	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
701347008080	acetyl esterase; Provisional; Region: PRK10162
701347008081	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
701347008082	high affinity sulphate transporter 1; Region: sulP; TIGR00815
701347008083	Sulfate transporter family; Region: Sulfate_transp; pfam00916
701347008084	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
701347008085	MltA-interacting protein MipA; Region: MipA; cl01504
701347008086	hypothetical protein; Provisional; Region: PRK05415
701347008087	Domain of unknown function (DUF697); Region: DUF697; cl12064
701347008088	Predicted ATPase [General function prediction only]; Region: COG3106
701347008089	Phage shock protein PspD (Phageshock_PspD); Region: Phageshock_PspD; cl11512
701347008090	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
701347008091	phage shock protein C; Region: phageshock_pspC; TIGR02978
701347008092	phage shock protein B; Provisional; Region: pspB; PRK09458
701347008093	phage shock protein PspA; Provisional; Region: PRK10698
701347008094	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
701347008095	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347008096	Walker A motif; other site
701347008097	ATP binding site [chemical binding]; other site
701347008098	Walker B motif; other site
701347008099	arginine finger; other site
701347008100	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347008101	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347008102	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
701347008103	peptide binding site [polypeptide binding]; other site
701347008104	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
701347008105	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008106	dimer interface [polypeptide binding]; other site
701347008107	conserved gate region; other site
701347008108	putative PBP binding loops; other site
701347008109	ABC-ATPase subunit interface; other site
701347008110	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
701347008111	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
701347008112	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008113	dimer interface [polypeptide binding]; other site
701347008114	conserved gate region; other site
701347008115	putative PBP binding loops; other site
701347008116	ABC-ATPase subunit interface; other site
701347008117	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
701347008118	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347008119	Walker A/P-loop; other site
701347008120	ATP binding site [chemical binding]; other site
701347008121	Q-loop/lid; other site
701347008122	ABC transporter signature motif; other site
701347008123	Walker B; other site
701347008124	D-loop; other site
701347008125	H-loop/switch region; other site
701347008126	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
701347008127	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
701347008128	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347008129	Walker A/P-loop; other site
701347008130	ATP binding site [chemical binding]; other site
701347008131	Q-loop/lid; other site
701347008132	ABC transporter signature motif; other site
701347008133	Walker B; other site
701347008134	D-loop; other site
701347008135	H-loop/switch region; other site
701347008136	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
701347008137	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
701347008138	NAD binding site [chemical binding]; other site
701347008139	homotetramer interface [polypeptide binding]; other site
701347008140	homodimer interface [polypeptide binding]; other site
701347008141	substrate binding site [chemical binding]; other site
701347008142	active site
701347008143	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731
701347008144	exoribonuclease II; Provisional; Region: PRK05054
701347008145	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
701347008146	RNB domain; Region: RNB; pfam00773
701347008147	S1 RNA binding domain; Region: S1; pfam00575
701347008148	RNase II stability modulator; Provisional; Region: PRK10060
701347008149	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347008150	putative active site [active]
701347008151	heme pocket [chemical binding]; other site
701347008152	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347008153	metal binding site [ion binding]; metal-binding site
701347008154	active site
701347008155	I-site; other site
701347008156	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347008157	hypothetical protein; Provisional; Region: PRK13658
701347008158	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
701347008159	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
701347008160	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347008161	lipoprotein; Provisional; Region: PRK10540
701347008162	translation initiation factor Sui1; Validated; Region: PRK06824
701347008163	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
701347008164	putative rRNA binding site [nucleotide binding]; other site
701347008165	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
701347008166	active site
701347008167	dimer interface [polypeptide binding]; other site
701347008168	tetratricopeptide repeat protein; Provisional; Region: PRK11788
701347008169	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347008170	binding surface
701347008171	TPR motif; other site
701347008172	Predicted membrane protein [Function unknown]; Region: COG3771
701347008173	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
701347008174	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
701347008175	active site
701347008176	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
701347008177	dimerization interface [polypeptide binding]; other site
701347008178	active site
701347008179	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
701347008180	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
701347008181	active site
701347008182	HIGH motif; other site
701347008183	dimer interface [polypeptide binding]; other site
701347008184	KMSKS motif; other site
701347008185	aconitate hydratase; Validated; Region: PRK09277
701347008186	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
701347008187	substrate binding site [chemical binding]; other site
701347008188	ligand binding site [chemical binding]; other site
701347008189	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
701347008190	substrate binding site [chemical binding]; other site
701347008191	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
701347008192	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347008193	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
701347008194	substrate binding site [chemical binding]; other site
701347008195	putative dimerization interface [polypeptide binding]; other site
701347008196	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
701347008197	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
701347008198	active site
701347008199	interdomain interaction site; other site
701347008200	putative metal-binding site [ion binding]; other site
701347008201	nucleotide binding site [chemical binding]; other site
701347008202	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
701347008203	domain I; other site
701347008204	DNA binding groove [nucleotide binding]
701347008205	phosphate binding site [ion binding]; other site
701347008206	domain II; other site
701347008207	domain III; other site
701347008208	nucleotide binding site [chemical binding]; other site
701347008209	catalytic site [active]
701347008210	domain IV; other site
701347008211	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
701347008212	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
701347008213	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
701347008214	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
701347008215	hypothetical protein; Provisional; Region: PRK11037
701347008216	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
701347008217	putative inner membrane peptidase; Provisional; Region: PRK11778
701347008218	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
701347008219	tandem repeat interface [polypeptide binding]; other site
701347008220	oligomer interface [polypeptide binding]; other site
701347008221	active site residues [active]
701347008222	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
701347008223	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
701347008224	NADP binding site [chemical binding]; other site
701347008225	homodimer interface [polypeptide binding]; other site
701347008226	active site
701347008227	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
701347008228	cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Validated; Region: PRK05986
701347008229	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
701347008230	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347008231	RNA binding surface [nucleotide binding]; other site
701347008232	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
701347008233	probable active site [active]
701347008234	hypothetical protein; Provisional; Region: PRK11630
701347008235	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
701347008236	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
701347008237	active site
701347008238	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
701347008239	anthranilate synthase component I; Provisional; Region: PRK13564
701347008240	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
701347008241	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
701347008242	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
701347008243	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
701347008244	glutamine binding [chemical binding]; other site
701347008245	catalytic triad [active]
701347008246	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
701347008247	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
701347008248	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
701347008249	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
701347008250	active site
701347008251	ribulose/triose binding site [chemical binding]; other site
701347008252	phosphate binding site [ion binding]; other site
701347008253	substrate (anthranilate) binding pocket [chemical binding]; other site
701347008254	product (indole) binding pocket [chemical binding]; other site
701347008255	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
701347008256	active site
701347008257	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
701347008258	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
701347008259	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347008260	catalytic residue [active]
701347008261	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
701347008262	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
701347008263	substrate binding site [chemical binding]; other site
701347008264	active site
701347008265	catalytic residues [active]
701347008266	heterodimer interface [polypeptide binding]; other site
701347008267	Transcriptional regulators [Transcription]; Region: MarR; COG1846
701347008268	MarR family; Region: MarR_2; pfam12802
701347008269	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
701347008270	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
701347008271	putative NAD(P) binding site [chemical binding]; other site
701347008272	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
701347008273	NAD(P) binding site [chemical binding]; other site
701347008274	diguanylate cyclase; Provisional; Region: PRK09894
701347008275	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
701347008276	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347008277	metal binding site [ion binding]; metal-binding site
701347008278	active site
701347008279	I-site; other site
701347008280	outer membrane protein W; Provisional; Region: PRK10959
701347008281	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
701347008282	hypothetical protein; Provisional; Region: PRK02868
701347008283	intracellular septation protein A; Reviewed; Region: PRK00259
701347008284	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
701347008285	YniB-like protein; Region: YniB; pfam14002
701347008286	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
701347008287	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
701347008288	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347008289	motif II; other site
701347008290	inner membrane protein; Provisional; Region: PRK11648
701347008291	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
701347008292	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
701347008293	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
701347008294	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
701347008295	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
701347008296	cell division modulator; Provisional; Region: PRK10113
701347008297	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
701347008298	putative active site [active]
701347008299	YdjC motif; other site
701347008300	Mg binding site [ion binding]; other site
701347008301	putative homodimer interface [polypeptide binding]; other site
701347008302	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
701347008303	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
701347008304	NAD binding site [chemical binding]; other site
701347008305	sugar binding site [chemical binding]; other site
701347008306	divalent metal binding site [ion binding]; other site
701347008307	tetramer (dimer of dimers) interface [polypeptide binding]; other site
701347008308	dimer interface [polypeptide binding]; other site
701347008309	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
701347008310	Cupin domain; Region: Cupin_2; pfam07883
701347008311	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347008312	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
701347008313	methionine cluster; other site
701347008314	active site
701347008315	phosphorylation site [posttranslational modification]
701347008316	metal binding site [ion binding]; metal-binding site
701347008317	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
701347008318	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
701347008319	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
701347008320	active site
701347008321	P-loop; other site
701347008322	phosphorylation site [posttranslational modification]
701347008323	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
701347008324	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
701347008325	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
701347008326	homodimer interface [polypeptide binding]; other site
701347008327	NAD binding pocket [chemical binding]; other site
701347008328	ATP binding pocket [chemical binding]; other site
701347008329	Mg binding site [ion binding]; other site
701347008330	active-site loop [active]
701347008331	hypothetical protein; Provisional; Region: PRK11396
701347008332	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
701347008333	dimer interface [polypeptide binding]; other site
701347008334	succinylglutamate desuccinylase; Provisional; Region: PRK05324
701347008335	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
701347008336	active site
701347008337	Zn binding site [ion binding]; other site
701347008338	succinylarginine dihydrolase; Provisional; Region: PRK13281
701347008339	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
701347008340	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
701347008341	NAD(P) binding site [chemical binding]; other site
701347008342	catalytic residues [active]
701347008343	arginine succinyltransferase; Provisional; Region: PRK10456
701347008344	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
701347008345	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
701347008346	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347008347	inhibitor-cofactor binding pocket; inhibition site
701347008348	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347008349	catalytic residue [active]
701347008350	mercuric reductase; Validated; Region: PRK06370
701347008351	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347008352	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
701347008353	RibD C-terminal domain; Region: RibD_C; cl17279
701347008354	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
701347008355	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
701347008356	catalytic residues [active]
701347008357	dimer interface [polypeptide binding]; other site
701347008358	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
701347008359	Phosphotransferase enzyme family; Region: APH; pfam01636
701347008360	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
701347008361	putative transposase OrfB; Reviewed; Region: PHA02517
701347008362	HTH-like domain; Region: HTH_21; pfam13276
701347008363	Integrase core domain; Region: rve; pfam00665
701347008364	Integrase core domain; Region: rve_3; pfam13683
701347008365	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
701347008366	DNA-binding interface [nucleotide binding]; DNA binding site
701347008367	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
701347008368	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
701347008369	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347008370	short chain dehydrogenase; Provisional; Region: PRK06180
701347008371	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
701347008372	NADP binding site [chemical binding]; other site
701347008373	active site
701347008374	steroid binding site; other site
701347008375	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
701347008376	EamA-like transporter family; Region: EamA; pfam00892
701347008377	EamA-like transporter family; Region: EamA; pfam00892
701347008378	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347008379	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347008380	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347008381	dimerization interface [polypeptide binding]; other site
701347008382	OpgC protein; Region: OpgC_C; cl17858
701347008383	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
701347008384	DXD motif; other site
701347008385	Protein of unknown function (DUF3131); Region: DUF3131; pfam11329
701347008386	Protein of unknown function (DUF3131); Region: DUF3131; pfam11329
701347008387	Protein of unknown function (DUF3131); Region: DUF3131; pfam11329
701347008388	PAS fold; Region: PAS_7; pfam12860
701347008389	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347008390	PAS fold; Region: PAS_3; pfam08447
701347008391	putative active site [active]
701347008392	heme pocket [chemical binding]; other site
701347008393	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347008394	dimer interface [polypeptide binding]; other site
701347008395	phosphorylation site [posttranslational modification]
701347008396	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347008397	ATP binding site [chemical binding]; other site
701347008398	Mg2+ binding site [ion binding]; other site
701347008399	G-X-G motif; other site
701347008400	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
701347008401	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347008402	active site
701347008403	phosphorylation site [posttranslational modification]
701347008404	intermolecular recognition site; other site
701347008405	dimerization interface [polypeptide binding]; other site
701347008406	Response regulator receiver domain; Region: Response_reg; pfam00072
701347008407	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347008408	active site
701347008409	phosphorylation site [posttranslational modification]
701347008410	intermolecular recognition site; other site
701347008411	dimerization interface [polypeptide binding]; other site
701347008412	FOG: HPt domain [Signal transduction mechanisms]; Region: ArcB; COG2198
701347008413	putative binding surface; other site
701347008414	active site
701347008415	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
701347008416	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
701347008417	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
701347008418	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
701347008419	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347008420	ATP binding site [chemical binding]; other site
701347008421	Mg2+ binding site [ion binding]; other site
701347008422	G-X-G motif; other site
701347008423	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
701347008424	anti sigma factor interaction site; other site
701347008425	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
701347008426	regulatory phosphorylation site [posttranslational modification]; other site
701347008427	Response regulator receiver domain; Region: Response_reg; pfam00072
701347008428	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347008429	active site
701347008430	phosphorylation site [posttranslational modification]
701347008431	intermolecular recognition site; other site
701347008432	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
701347008433	dimerization interface [polypeptide binding]; other site
701347008434	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
701347008435	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
701347008436	homodimer interface [polypeptide binding]; other site
701347008437	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
701347008438	active site pocket [active]
701347008439	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
701347008440	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
701347008441	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
701347008442	active site
701347008443	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
701347008444	DNA-binding site [nucleotide binding]; DNA binding site
701347008445	RNA-binding motif; other site
701347008446	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
701347008447	putative catalytic site [active]
701347008448	putative phosphate binding site [ion binding]; other site
701347008449	active site
701347008450	metal binding site A [ion binding]; metal-binding site
701347008451	DNA binding site [nucleotide binding]
701347008452	putative AP binding site [nucleotide binding]; other site
701347008453	putative metal binding site B [ion binding]; other site
701347008454	Uncharacterized conserved protein [Function unknown]; Region: COG0398
701347008455	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
701347008456	Uncharacterized conserved protein [Function unknown]; Region: COG0398
701347008457	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
701347008458	hypothetical protein; Provisional; Region: PRK11622
701347008459	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
701347008460	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008461	ABC-ATPase subunit interface; other site
701347008462	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
701347008463	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347008464	Walker A/P-loop; other site
701347008465	ATP binding site [chemical binding]; other site
701347008466	Q-loop/lid; other site
701347008467	ABC transporter signature motif; other site
701347008468	Walker B; other site
701347008469	D-loop; other site
701347008470	H-loop/switch region; other site
701347008471	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
701347008472	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
701347008473	active site residue [active]
701347008474	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
701347008475	active site residue [active]
701347008476	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
701347008477	Uncharacterized conserved protein [Function unknown]; Region: COG2128
701347008478	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
701347008479	active site
701347008480	8-oxo-dGMP binding site [chemical binding]; other site
701347008481	nudix motif; other site
701347008482	metal binding site [ion binding]; metal-binding site
701347008483	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
701347008484	glutamate dehydrogenase; Provisional; Region: PRK09414
701347008485	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
701347008486	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
701347008487	NAD(P) binding site [chemical binding]; other site
701347008488	Beta-lactamase; Region: Beta-lactamase; cl17358
701347008489	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
701347008490	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
701347008491	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
701347008492	active site turn [active]
701347008493	phosphorylation site [posttranslational modification]
701347008494	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347008495	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; pfam09829
701347008496	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347008497	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347008498	trimer interface [polypeptide binding]; other site
701347008499	eyelet of channel; other site
701347008500	transcriptional regulator MurR; Provisional; Region: PRK15482
701347008501	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347008502	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347008503	putative active site [active]
701347008504	DNA topoisomerase III; Provisional; Region: PRK07726
701347008505	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
701347008506	active site
701347008507	putative interdomain interaction site [polypeptide binding]; other site
701347008508	putative metal-binding site [ion binding]; other site
701347008509	putative nucleotide binding site [chemical binding]; other site
701347008510	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
701347008511	domain I; other site
701347008512	DNA binding groove [nucleotide binding]
701347008513	phosphate binding site [ion binding]; other site
701347008514	domain II; other site
701347008515	domain III; other site
701347008516	nucleotide binding site [chemical binding]; other site
701347008517	catalytic site [active]
701347008518	domain IV; other site
701347008519	selenophosphate synthetase; Provisional; Region: PRK00943
701347008520	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
701347008521	dimerization interface [polypeptide binding]; other site
701347008522	putative ATP binding site [chemical binding]; other site
701347008523	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
701347008524	active site
701347008525	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
701347008526	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
701347008527	putative FMN binding site [chemical binding]; other site
701347008528	protease 4; Provisional; Region: PRK10949
701347008529	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
701347008530	tandem repeat interface [polypeptide binding]; other site
701347008531	oligomer interface [polypeptide binding]; other site
701347008532	active site residues [active]
701347008533	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
701347008534	tandem repeat interface [polypeptide binding]; other site
701347008535	oligomer interface [polypeptide binding]; other site
701347008536	active site residues [active]
701347008537	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
701347008538	active site
701347008539	homodimer interface [polypeptide binding]; other site
701347008540	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
701347008541	Isochorismatase family; Region: Isochorismatase; pfam00857
701347008542	catalytic triad [active]
701347008543	metal binding site [ion binding]; metal-binding site
701347008544	conserved cis-peptide bond; other site
701347008545	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
701347008546	methionine sulfoxide reductase B; Provisional; Region: PRK00222
701347008547	SelR domain; Region: SelR; pfam01641
701347008548	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
701347008549	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
701347008550	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
701347008551	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
701347008552	active site
701347008553	phosphate binding residues; other site
701347008554	catalytic residues [active]
701347008555	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
701347008556	PrkA family serine protein kinase; Provisional; Region: PRK15455
701347008557	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347008558	Walker A motif; other site
701347008559	ATP binding site [chemical binding]; other site
701347008560	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
701347008561	hypothetical protein; Provisional; Region: PRK05325
701347008562	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347008563	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
701347008564	substrate binding site [chemical binding]; other site
701347008565	nickel transporter permease NikB; Provisional; Region: PRK10352
701347008566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008567	dimer interface [polypeptide binding]; other site
701347008568	conserved gate region; other site
701347008569	putative PBP binding loops; other site
701347008570	ABC-ATPase subunit interface; other site
701347008571	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
701347008572	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008573	dimer interface [polypeptide binding]; other site
701347008574	conserved gate region; other site
701347008575	putative PBP binding loops; other site
701347008576	ABC-ATPase subunit interface; other site
701347008577	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
701347008578	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347008579	Walker A/P-loop; other site
701347008580	ATP binding site [chemical binding]; other site
701347008581	Q-loop/lid; other site
701347008582	ABC transporter signature motif; other site
701347008583	Walker B; other site
701347008584	D-loop; other site
701347008585	H-loop/switch region; other site
701347008586	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
701347008587	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
701347008588	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347008589	Walker A/P-loop; other site
701347008590	ATP binding site [chemical binding]; other site
701347008591	Q-loop/lid; other site
701347008592	ABC transporter signature motif; other site
701347008593	Walker B; other site
701347008594	D-loop; other site
701347008595	H-loop/switch region; other site
701347008596	nickel responsive regulator; Provisional; Region: PRK02967
701347008597	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
701347008598	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
701347008599	serine racemase; Region: PLN02970
701347008600	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
701347008601	tetramer interface [polypeptide binding]; other site
701347008602	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347008603	catalytic residue [active]
701347008604	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
701347008605	homotrimer interaction site [polypeptide binding]; other site
701347008606	putative active site [active]
701347008607	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
701347008608	YheO-like PAS domain; Region: PAS_6; pfam08348
701347008609	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
701347008610	DNA-binding interface [nucleotide binding]; DNA binding site
701347008611	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
701347008612	putative deacylase active site [active]
701347008613	Predicted membrane protein [Function unknown]; Region: COG2707
701347008614	Cupin domain; Region: Cupin_2; cl17218
701347008615	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347008616	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
701347008617	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347008618	hypothetical protein; Validated; Region: PRK06186
701347008619	conserved cys residue [active]
701347008620	Uncharacterized conserved protein [Function unknown]; Region: COG3189
701347008621	Domain of unknown function (DUF333); Region: DUF333; pfam03891
701347008622	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
701347008623	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
701347008624	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
701347008625	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347008626	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347008627	metal binding site [ion binding]; metal-binding site
701347008628	active site
701347008629	I-site; other site
701347008630	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347008631	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347008632	metal binding site [ion binding]; metal-binding site
701347008633	active site
701347008634	I-site; other site
701347008635	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
701347008636	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
701347008637	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
701347008638	Isochorismatase family; Region: Isochorismatase; pfam00857
701347008639	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
701347008640	catalytic triad [active]
701347008641	dimer interface [polypeptide binding]; other site
701347008642	conserved cis-peptide bond; other site
701347008643	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347008644	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347008645	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
701347008646	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
701347008647	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347008648	putative oxidoreductase; Provisional; Region: PRK11579
701347008649	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347008650	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
701347008651	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
701347008652	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347008653	Ligand Binding Site [chemical binding]; other site
701347008654	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
701347008655	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
701347008656	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
701347008657	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
701347008658	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
701347008659	Autotransporter beta-domain; Region: Autotransporter; pfam03797
701347008660	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
701347008661	Acyltransferase family; Region: Acyl_transf_3; pfam01757
701347008662	isocitrate dehydrogenase; Validated; Region: PRK07362
701347008663	isocitrate dehydrogenase; Reviewed; Region: PRK07006
701347008664	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
701347008665	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
701347008666	active site
701347008667	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
701347008668	nudix motif; other site
701347008669	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
701347008670	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
701347008671	putative lysogenization regulator; Reviewed; Region: PRK00218
701347008672	adenylosuccinate lyase; Provisional; Region: PRK09285
701347008673	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
701347008674	tetramer interface [polypeptide binding]; other site
701347008675	active site
701347008676	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
701347008677	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347008678	active site
701347008679	phosphorylation site [posttranslational modification]
701347008680	intermolecular recognition site; other site
701347008681	dimerization interface [polypeptide binding]; other site
701347008682	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347008683	DNA binding site [nucleotide binding]
701347008684	sensor protein PhoQ; Provisional; Region: PRK10815
701347008685	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
701347008686	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
701347008687	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347008688	ATP binding site [chemical binding]; other site
701347008689	Mg2+ binding site [ion binding]; other site
701347008690	G-X-G motif; other site
701347008691	Uncharacterized conserved protein [Function unknown]; Region: COG2850
701347008692	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
701347008693	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
701347008694	metal binding site [ion binding]; metal-binding site
701347008695	dimer interface [polypeptide binding]; other site
701347008696	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
701347008697	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347008698	Walker A/P-loop; other site
701347008699	ATP binding site [chemical binding]; other site
701347008700	Q-loop/lid; other site
701347008701	ABC transporter signature motif; other site
701347008702	Walker B; other site
701347008703	D-loop; other site
701347008704	H-loop/switch region; other site
701347008705	TOBE domain; Region: TOBE_2; pfam08402
701347008706	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008707	dimer interface [polypeptide binding]; other site
701347008708	conserved gate region; other site
701347008709	putative PBP binding loops; other site
701347008710	ABC-ATPase subunit interface; other site
701347008711	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
701347008712	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347008713	dimer interface [polypeptide binding]; other site
701347008714	conserved gate region; other site
701347008715	putative PBP binding loops; other site
701347008716	ABC-ATPase subunit interface; other site
701347008717	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
701347008718	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
701347008719	NAD-dependent deacetylase; Provisional; Region: PRK00481
701347008720	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
701347008721	NAD+ binding site [chemical binding]; other site
701347008722	substrate binding site [chemical binding]; other site
701347008723	Zn binding site [ion binding]; other site
701347008724	fructokinase; Reviewed; Region: PRK09557
701347008725	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347008726	nucleotide binding site [chemical binding]; other site
701347008727	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
701347008728	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
701347008729	FtsX-like permease family; Region: FtsX; pfam02687
701347008730	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
701347008731	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
701347008732	Walker A/P-loop; other site
701347008733	ATP binding site [chemical binding]; other site
701347008734	Q-loop/lid; other site
701347008735	ABC transporter signature motif; other site
701347008736	Walker B; other site
701347008737	D-loop; other site
701347008738	H-loop/switch region; other site
701347008739	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
701347008740	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
701347008741	FtsX-like permease family; Region: FtsX; pfam02687
701347008742	hypothetical protein; Provisional; Region: PRK09867
701347008743	transcription-repair coupling factor; Provisional; Region: PRK10689
701347008744	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
701347008745	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347008746	ATP binding site [chemical binding]; other site
701347008747	putative Mg++ binding site [ion binding]; other site
701347008748	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347008749	nucleotide binding region [chemical binding]; other site
701347008750	ATP-binding site [chemical binding]; other site
701347008751	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
701347008752	L,D-transpeptidase; Provisional; Region: PRK10260
701347008753	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347008754	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347008755	Domain of unknown function (DUF4330); Region: DUF4330; pfam14221
701347008756	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347008757	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347008758	PapC N-terminal domain; Region: PapC_N; pfam13954
701347008759	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347008760	PapC C-terminal domain; Region: PapC_C; pfam13953
701347008761	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
701347008762	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347008763	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347008764	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347008765	hypothetical protein; Provisional; Region: PRK11280
701347008766	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
701347008767	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347008768	hypothetical protein; Provisional; Region: PRK04940
701347008769	beta-hexosaminidase; Provisional; Region: PRK05337
701347008770	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
701347008771	thiamine kinase; Region: ycfN_thiK; TIGR02721
701347008772	thiamine kinase; Provisional; Region: thiK; PRK10271
701347008773	substrate binding site [chemical binding]; other site
701347008774	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
701347008775	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
701347008776	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
701347008777	putative dimer interface [polypeptide binding]; other site
701347008778	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
701347008779	nucleotide binding site/active site [active]
701347008780	HIT family signature motif; other site
701347008781	catalytic residue [active]
701347008782	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
701347008783	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347008784	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347008785	active site turn [active]
701347008786	phosphorylation site [posttranslational modification]
701347008787	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
701347008788	active site
701347008789	DNA polymerase III subunit delta'; Validated; Region: PRK07993
701347008790	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
701347008791	thymidylate kinase; Validated; Region: tmk; PRK00698
701347008792	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
701347008793	TMP-binding site; other site
701347008794	ATP-binding site [chemical binding]; other site
701347008795	conserved hypothetical protein, YceG family; Region: TIGR00247
701347008796	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
701347008797	dimerization interface [polypeptide binding]; other site
701347008798	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
701347008799	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
701347008800	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347008801	catalytic residue [active]
701347008802	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
701347008803	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
701347008804	dimer interface [polypeptide binding]; other site
701347008805	active site
701347008806	acyl carrier protein; Provisional; Region: acpP; PRK00982
701347008807	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
701347008808	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
701347008809	NAD(P) binding site [chemical binding]; other site
701347008810	homotetramer interface [polypeptide binding]; other site
701347008811	homodimer interface [polypeptide binding]; other site
701347008812	active site
701347008813	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
701347008814	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
701347008815	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
701347008816	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
701347008817	dimer interface [polypeptide binding]; other site
701347008818	active site
701347008819	CoA binding pocket [chemical binding]; other site
701347008820	putative phosphate acyltransferase; Provisional; Region: PRK05331
701347008821	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
701347008822	hypothetical protein; Provisional; Region: PRK11193
701347008823	Maf-like protein; Region: Maf; pfam02545
701347008824	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
701347008825	active site
701347008826	dimer interface [polypeptide binding]; other site
701347008827	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
701347008828	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347008829	RNA binding surface [nucleotide binding]; other site
701347008830	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
701347008831	active site
701347008832	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
701347008833	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
701347008834	homodimer interface [polypeptide binding]; other site
701347008835	oligonucleotide binding site [chemical binding]; other site
701347008836	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
701347008837	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
701347008838	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
701347008839	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
701347008840	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
701347008841	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
701347008842	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
701347008843	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
701347008844	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
701347008845	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
701347008846	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
701347008847	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
701347008848	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
701347008849	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
701347008850	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
701347008851	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
701347008852	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
701347008853	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
701347008854	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
701347008855	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
701347008856	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
701347008857	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
701347008858	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
701347008859	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
701347008860	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
701347008861	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
701347008862	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
701347008863	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
701347008864	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
701347008865	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
701347008866	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
701347008867	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
701347008868	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
701347008869	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
701347008870	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
701347008871	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
701347008872	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
701347008873	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
701347008874	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
701347008875	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
701347008876	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
701347008877	hypothetical protein; Provisional; Region: PRK11239
701347008878	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
701347008879	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
701347008880	multidrug resistance protein MdtH; Provisional; Region: PRK11646
701347008881	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347008882	putative substrate translocation pore; other site
701347008883	lipoprotein; Provisional; Region: PRK10598
701347008884	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
701347008885	active site
701347008886	substrate binding pocket [chemical binding]; other site
701347008887	dimer interface [polypeptide binding]; other site
701347008888	DNA damage-inducible protein I; Provisional; Region: PRK10597
701347008889	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
701347008890	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
701347008891	hydroxyglutarate oxidase; Provisional; Region: PRK11728
701347008892	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
701347008893	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
701347008894	active site residue [active]
701347008895	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
701347008896	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
701347008897	putative acyl-acceptor binding pocket; other site
701347008898	drug efflux system protein MdtG; Provisional; Region: PRK09874
701347008899	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347008900	putative substrate translocation pore; other site
701347008901	secY/secA suppressor protein; Provisional; Region: PRK11467
701347008902	lipoprotein; Provisional; Region: PRK10175
701347008903	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
701347008904	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
701347008905	Ligand binding site; other site
701347008906	DXD motif; other site
701347008907	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
701347008908	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
701347008909	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
701347008910	Acyltransferase family; Region: Acyl_transf_3; pfam01757
701347008911	Fimbrial protein; Region: Fimbrial; cl01416
701347008912	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
701347008913	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347008914	DNA binding residues [nucleotide binding]
701347008915	dimerization interface [polypeptide binding]; other site
701347008916	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
701347008917	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
701347008918	putative hydrolase; Validated; Region: PRK09248
701347008919	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
701347008920	active site
701347008921	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
701347008922	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
701347008923	putative ligand binding site [chemical binding]; other site
701347008924	NAD binding site [chemical binding]; other site
701347008925	dimerization interface [polypeptide binding]; other site
701347008926	catalytic site [active]
701347008927	Fimbrial protein; Region: Fimbrial; pfam00419
701347008928	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
701347008929	PapC N-terminal domain; Region: PapC_N; pfam13954
701347008930	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347008931	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
701347008932	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347008933	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347008934	Fimbrial protein; Region: Fimbrial; cl01416
701347008935	LysR family transcriptional regulator; Provisional; Region: PRK14997
701347008936	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347008937	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
701347008938	putative effector binding pocket; other site
701347008939	putative dimerization interface [polypeptide binding]; other site
701347008940	Pirin-related protein [General function prediction only]; Region: COG1741
701347008941	Pirin; Region: Pirin; pfam02678
701347008942	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
701347008943	Isochorismatase family; Region: Isochorismatase; pfam00857
701347008944	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
701347008945	catalytic triad [active]
701347008946	dimer interface [polypeptide binding]; other site
701347008947	conserved cis-peptide bond; other site
701347008948	hypothetical protein; Provisional; Region: PRK10536
701347008949	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
701347008950	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
701347008951	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
701347008952	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
701347008953	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
701347008954	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
701347008955	Imelysin; Region: Peptidase_M75; pfam09375
701347008956	FTR1 family protein; Region: TIGR00145
701347008957	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
701347008958	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
701347008959	Nucleoside recognition; Region: Gate; pfam07670
701347008960	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
701347008961	Protein of unknown function (DUF3574); Region: DUF3574; pfam12098
701347008962	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
701347008963	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
701347008964	Na binding site [ion binding]; other site
701347008965	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
701347008966	Predicted transcriptional regulator [Transcription]; Region: COG3905
701347008967	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
701347008968	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
701347008969	Glutamate binding site [chemical binding]; other site
701347008970	NAD binding site [chemical binding]; other site
701347008971	catalytic residues [active]
701347008972	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
701347008973	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
701347008974	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347008975	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
701347008976	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
701347008977	EamA-like transporter family; Region: EamA; pfam00892
701347008978	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
701347008979	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
701347008980	hypothetical protein; Provisional; Region: PRK10174
701347008981	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
701347008982	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
701347008983	catalytic core [active]
701347008984	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
701347008985	Predicted transcriptional regulators [Transcription]; Region: COG1733
701347008986	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
701347008987	short chain dehydrogenase; Provisional; Region: PRK06500
701347008988	classical (c) SDRs; Region: SDR_c; cd05233
701347008989	NAD(P) binding site [chemical binding]; other site
701347008990	active site
701347008991	voltage-gated potassium channel; Provisional; Region: PRK10537
701347008992	Ion channel; Region: Ion_trans_2; pfam07885
701347008993	TrkA-N domain; Region: TrkA_N; pfam02254
701347008994	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
701347008995	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347008996	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347008997	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
701347008998	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
701347008999	Walker A/P-loop; other site
701347009000	ATP binding site [chemical binding]; other site
701347009001	Q-loop/lid; other site
701347009002	ABC transporter signature motif; other site
701347009003	Walker B; other site
701347009004	D-loop; other site
701347009005	H-loop/switch region; other site
701347009006	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
701347009007	Walker A/P-loop; other site
701347009008	ATP binding site [chemical binding]; other site
701347009009	Q-loop/lid; other site
701347009010	ABC transporter signature motif; other site
701347009011	Walker B; other site
701347009012	D-loop; other site
701347009013	H-loop/switch region; other site
701347009014	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
701347009015	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
701347009016	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
701347009017	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
701347009018	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
701347009019	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
701347009020	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
701347009021	NAD(P) binding site [chemical binding]; other site
701347009022	catalytic residues [active]
701347009023	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
701347009024	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347009025	Walker A motif; other site
701347009026	ATP binding site [chemical binding]; other site
701347009027	Walker B motif; other site
701347009028	arginine finger; other site
701347009029	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347009030	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
701347009031	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
701347009032	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
701347009033	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
701347009034	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
701347009035	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
701347009036	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347009037	catalytic loop [active]
701347009038	iron binding site [ion binding]; other site
701347009039	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
701347009040	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
701347009041	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
701347009042	PAS domain; Region: PAS; smart00091
701347009043	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347009044	Walker A motif; other site
701347009045	ATP binding site [chemical binding]; other site
701347009046	Walker B motif; other site
701347009047	arginine finger; other site
701347009048	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347009049	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
701347009050	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
701347009051	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
701347009052	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
701347009053	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
701347009054	catalytic residue [active]
701347009055	peptidase; Reviewed; Region: PRK13004
701347009056	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
701347009057	putative metal binding site [ion binding]; other site
701347009058	putative dimer interface [polypeptide binding]; other site
701347009059	phenylhydantoinase; Validated; Region: PRK08323
701347009060	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
701347009061	tetramer interface [polypeptide binding]; other site
701347009062	active site
701347009063	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
701347009064	carbamate kinase; Reviewed; Region: PRK12686
701347009065	putative substrate binding site [chemical binding]; other site
701347009066	homodimer interface [polypeptide binding]; other site
701347009067	nucleotide binding site [chemical binding]; other site
701347009068	nucleotide binding site [chemical binding]; other site
701347009069	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
701347009070	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
701347009071	XdhC Rossmann domain; Region: XdhC_C; pfam13478
701347009072	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
701347009073	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
701347009074	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
701347009075	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
701347009076	Ligand binding site; other site
701347009077	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
701347009078	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
701347009079	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
701347009080	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347009081	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
701347009082	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
701347009083	active site
701347009084	putative substrate binding pocket [chemical binding]; other site
701347009085	putative oxidoreductase; Provisional; Region: PRK09799
701347009086	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
701347009087	putative hypoxanthine oxidase; Provisional; Region: PRK09800
701347009088	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
701347009089	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; cl03161
701347009090	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
701347009091	xanthine permease; Region: pbuX; TIGR03173
701347009092	guanine deaminase; Provisional; Region: PRK09228
701347009093	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
701347009094	active site
701347009095	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
701347009096	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
701347009097	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
701347009098	4Fe-4S binding domain; Region: Fer4; pfam00037
701347009099	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347009100	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347009101	xanthine permease; Region: pbuX; TIGR03173
701347009102	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347009103	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347009104	metal binding site [ion binding]; metal-binding site
701347009105	active site
701347009106	I-site; other site
701347009107	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
701347009108	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
701347009109	Walker A/P-loop; other site
701347009110	ATP binding site [chemical binding]; other site
701347009111	Q-loop/lid; other site
701347009112	ABC transporter signature motif; other site
701347009113	Walker B; other site
701347009114	D-loop; other site
701347009115	H-loop/switch region; other site
701347009116	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
701347009117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009118	dimer interface [polypeptide binding]; other site
701347009119	conserved gate region; other site
701347009120	ABC-ATPase subunit interface; other site
701347009121	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009122	dimer interface [polypeptide binding]; other site
701347009123	conserved gate region; other site
701347009124	putative PBP binding loops; other site
701347009125	ABC-ATPase subunit interface; other site
701347009126	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
701347009127	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
701347009128	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
701347009129	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
701347009130	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
701347009131	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
701347009132	DNA binding residues [nucleotide binding]
701347009133	Chitin binding Peritrophin-A domain; Region: CBM_14; cl02629
701347009134	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347009135	binding surface
701347009136	TPR motif; other site
701347009137	Tetratricopeptide repeat; Region: TPR_16; pfam13432
701347009138	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
701347009139	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
701347009140	FMN-binding pocket [chemical binding]; other site
701347009141	flavin binding motif; other site
701347009142	phosphate binding motif [ion binding]; other site
701347009143	beta-alpha-beta structure motif; other site
701347009144	NAD binding pocket [chemical binding]; other site
701347009145	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347009146	catalytic loop [active]
701347009147	iron binding site [ion binding]; other site
701347009148	succinic semialdehyde dehydrogenase; Region: PLN02278
701347009149	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
701347009150	tetramerization interface [polypeptide binding]; other site
701347009151	NAD(P) binding site [chemical binding]; other site
701347009152	catalytic residues [active]
701347009153	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
701347009154	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
701347009155	[2Fe-2S] cluster binding site [ion binding]; other site
701347009156	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
701347009157	putative alpha subunit interface [polypeptide binding]; other site
701347009158	putative active site [active]
701347009159	putative substrate binding site [chemical binding]; other site
701347009160	Fe binding site [ion binding]; other site
701347009161	putative transporter; Provisional; Region: PRK09950
701347009162	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
701347009163	tartrate dehydrogenase; Region: TTC; TIGR02089
701347009164	transcriptional activator TtdR; Provisional; Region: PRK09801
701347009165	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347009166	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
701347009167	putative effector binding pocket; other site
701347009168	putative dimerization interface [polypeptide binding]; other site
701347009169	Protein of unknown function (DUF2573); Region: DUF2573; pfam10835
701347009170	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347009171	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
701347009172	active site 2 [active]
701347009173	active site 1 [active]
701347009174	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
701347009175	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
701347009176	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
701347009177	FMN binding site [chemical binding]; other site
701347009178	active site
701347009179	substrate binding site [chemical binding]; other site
701347009180	catalytic residue [active]
701347009181	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
701347009182	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347009183	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
701347009184	DNA binding site [nucleotide binding]
701347009185	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
701347009186	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
701347009187	peptide binding site [polypeptide binding]; other site
701347009188	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
701347009189	YccA-like proteins; Region: YccA_like; cd10433
701347009190	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
701347009191	sulfur transfer protein TusE; Provisional; Region: PRK11508
701347009192	acylphosphatase; Provisional; Region: PRK14426
701347009193	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
701347009194	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
701347009195	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
701347009196	putative RNA binding site [nucleotide binding]; other site
701347009197	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347009198	S-adenosylmethionine binding site [chemical binding]; other site
701347009199	heat shock protein HspQ; Provisional; Region: PRK14129
701347009200	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
701347009201	hypothetical protein; Provisional; Region: PRK03641
701347009202	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
701347009203	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
701347009204	active site
701347009205	dimer interfaces [polypeptide binding]; other site
701347009206	catalytic residues [active]
701347009207	DNA helicase IV; Provisional; Region: helD; PRK11054
701347009208	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
701347009209	Part of AAA domain; Region: AAA_19; pfam13245
701347009210	Family description; Region: UvrD_C_2; pfam13538
701347009211	Predicted membrane protein [Function unknown]; Region: COG3304
701347009212	Domain of unknown function (DUF307); Region: DUF307; pfam03733
701347009213	Domain of unknown function (DUF307); Region: DUF307; pfam03733
701347009214	TIGR01666 family membrane protein; Region: YCCS
701347009215	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
701347009216	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
701347009217	TfoX N-terminal domain; Region: TfoX_N; pfam04993
701347009218	TfoX C-terminal domain; Region: TfoX_C; pfam04994
701347009219	SOS cell division inhibitor; Provisional; Region: PRK10595
701347009220	outer membrane protein A; Reviewed; Region: PRK10808
701347009221	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
701347009222	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347009223	ligand binding site [chemical binding]; other site
701347009224	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
701347009225	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
701347009226	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
701347009227	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
701347009228	active site 1 [active]
701347009229	dimer interface [polypeptide binding]; other site
701347009230	active site 2 [active]
701347009231	Ribosome modulation factor; Region: RMF; pfam04957
701347009232	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
701347009233	Protein of unknown function (DUF330); Region: DUF330; pfam03886
701347009234	paraquat-inducible protein B; Provisional; Region: PRK10807
701347009235	mce related protein; Region: MCE; pfam02470
701347009236	mce related protein; Region: MCE; pfam02470
701347009237	mce related protein; Region: MCE; pfam02470
701347009238	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
701347009239	Paraquat-inducible protein A; Region: PqiA; pfam04403
701347009240	Paraquat-inducible protein A; Region: PqiA; pfam04403
701347009241	ABC transporter ATPase component; Reviewed; Region: PRK11147
701347009242	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009243	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009244	Walker A/P-loop; other site
701347009245	Walker A/P-loop; other site
701347009246	ATP binding site [chemical binding]; other site
701347009247	ATP binding site [chemical binding]; other site
701347009248	Q-loop/lid; other site
701347009249	Q-loop/lid; other site
701347009250	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347009251	ABC transporter signature motif; other site
701347009252	Walker B; other site
701347009253	D-loop; other site
701347009254	ABC transporter; Region: ABC_tran_2; pfam12848
701347009255	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347009256	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
701347009257	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
701347009258	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
701347009259	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347009260	S-adenosylmethionine binding site [chemical binding]; other site
701347009261	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
701347009262	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
701347009263	MOSC domain; Region: MOSC; pfam03473
701347009264	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
701347009265	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347009266	catalytic loop [active]
701347009267	iron binding site [ion binding]; other site
701347009268	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
701347009269	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
701347009270	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
701347009271	quinone interaction residues [chemical binding]; other site
701347009272	active site
701347009273	catalytic residues [active]
701347009274	FMN binding site [chemical binding]; other site
701347009275	substrate binding site [chemical binding]; other site
701347009276	aminopeptidase N; Provisional; Region: pepN; PRK14015
701347009277	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
701347009278	active site
701347009279	Zn binding site [ion binding]; other site
701347009280	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
701347009281	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
701347009282	active site
701347009283	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
701347009284	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
701347009285	putative dimer interface [polypeptide binding]; other site
701347009286	putative anticodon binding site; other site
701347009287	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
701347009288	homodimer interface [polypeptide binding]; other site
701347009289	motif 1; other site
701347009290	motif 2; other site
701347009291	active site
701347009292	motif 3; other site
701347009293	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347009294	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347009295	trimer interface [polypeptide binding]; other site
701347009296	eyelet of channel; other site
701347009297	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
701347009298	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347009299	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347009300	homodimer interface [polypeptide binding]; other site
701347009301	catalytic residue [active]
701347009302	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
701347009303	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
701347009304	Peptidase M15; Region: Peptidase_M15_3; cl01194
701347009305	murein L,D-transpeptidase; Provisional; Region: PRK10594
701347009306	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
701347009307	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347009308	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347009309	cell division protein MukB; Provisional; Region: mukB; PRK04863
701347009310	P-loop containing region of AAA domain; Region: AAA_29; cl17516
701347009311	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
701347009312	condesin subunit E; Provisional; Region: PRK05256
701347009313	condesin subunit F; Provisional; Region: PRK05260
701347009314	Methyltransferase domain; Region: Methyltransf_31; pfam13847
701347009315	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347009316	S-adenosylmethionine binding site [chemical binding]; other site
701347009317	Uncharacterized conserved protein [Function unknown]; Region: COG1434
701347009318	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
701347009319	putative active site [active]
701347009320	hypothetical protein; Provisional; Region: PRK10593
701347009321	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
701347009322	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
701347009323	Ligand binding site; other site
701347009324	oligomer interface; other site
701347009325	Trm112p-like protein; Region: Trm112p; cl01066
701347009326	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
701347009327	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
701347009328	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
701347009329	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
701347009330	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
701347009331	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
701347009332	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
701347009333	Walker A/P-loop; other site
701347009334	ATP binding site [chemical binding]; other site
701347009335	Q-loop/lid; other site
701347009336	ABC transporter signature motif; other site
701347009337	Walker B; other site
701347009338	D-loop; other site
701347009339	H-loop/switch region; other site
701347009340	ComEC family competence protein; Provisional; Region: PRK11539
701347009341	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
701347009342	Competence protein; Region: Competence; pfam03772
701347009343	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
701347009344	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
701347009345	IHF dimer interface [polypeptide binding]; other site
701347009346	IHF - DNA interface [nucleotide binding]; other site
701347009347	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
701347009348	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
701347009349	RNA binding site [nucleotide binding]; other site
701347009350	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
701347009351	RNA binding site [nucleotide binding]; other site
701347009352	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
701347009353	RNA binding site [nucleotide binding]; other site
701347009354	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
701347009355	RNA binding site [nucleotide binding]; other site
701347009356	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
701347009357	RNA binding site [nucleotide binding]; other site
701347009358	cytidylate kinase; Provisional; Region: cmk; PRK00023
701347009359	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
701347009360	CMP-binding site; other site
701347009361	The sites determining sugar specificity; other site
701347009362	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
701347009363	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
701347009364	putative active site [active]
701347009365	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
701347009366	homodimer interface [polypeptide binding]; other site
701347009367	substrate-cofactor binding pocket; other site
701347009368	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347009369	catalytic residue [active]
701347009370	uncharacterized domain; Region: TIGR00702
701347009371	YcaO-like family; Region: YcaO; pfam02624
701347009372	formate transporter; Provisional; Region: PRK10805
701347009373	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
701347009374	Pyruvate formate lyase 1; Region: PFL1; cd01678
701347009375	coenzyme A binding site [chemical binding]; other site
701347009376	active site
701347009377	catalytic residues [active]
701347009378	glycine loop; other site
701347009379	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
701347009380	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347009381	FeS/SAM binding site; other site
701347009382	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347009383	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
701347009384	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
701347009385	putative active site [active]
701347009386	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
701347009387	active site
701347009388	P-loop; other site
701347009389	phosphorylation site [posttranslational modification]
701347009390	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
701347009391	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
701347009392	TPP-binding site [chemical binding]; other site
701347009393	dimer interface [polypeptide binding]; other site
701347009394	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
701347009395	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
701347009396	PYR/PP interface [polypeptide binding]; other site
701347009397	dimer interface [polypeptide binding]; other site
701347009398	TPP binding site [chemical binding]; other site
701347009399	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
701347009400	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347009401	active site
701347009402	phosphorylation site [posttranslational modification]
701347009403	inner membrane transporter YjeM; Provisional; Region: PRK15238
701347009404	putative MFS family transporter protein; Provisional; Region: PRK03633
701347009405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347009406	putative substrate translocation pore; other site
701347009407	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
701347009408	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
701347009409	4Fe-4S binding domain; Region: Fer4; pfam00037
701347009410	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
701347009411	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
701347009412	putative [Fe4-S4] binding site [ion binding]; other site
701347009413	putative molybdopterin cofactor binding site [chemical binding]; other site
701347009414	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
701347009415	putative molybdopterin cofactor binding site; other site
701347009416	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
701347009417	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
701347009418	4Fe-4S binding domain; Region: Fer4; pfam00037
701347009419	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
701347009420	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
701347009421	putative [Fe4-S4] binding site [ion binding]; other site
701347009422	putative molybdopterin cofactor binding site [chemical binding]; other site
701347009423	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
701347009424	putative molybdopterin cofactor binding site; other site
701347009425	seryl-tRNA synthetase; Provisional; Region: PRK05431
701347009426	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
701347009427	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
701347009428	dimer interface [polypeptide binding]; other site
701347009429	active site
701347009430	motif 1; other site
701347009431	motif 2; other site
701347009432	motif 3; other site
701347009433	recombination factor protein RarA; Reviewed; Region: PRK13342
701347009434	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347009435	Walker A motif; other site
701347009436	ATP binding site [chemical binding]; other site
701347009437	Walker B motif; other site
701347009438	arginine finger; other site
701347009439	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
701347009440	periplasmic chaperone LolA; Region: lolA; TIGR00547
701347009441	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
701347009442	DNA translocase FtsK; Provisional; Region: PRK10263
701347009443	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
701347009444	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
701347009445	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
701347009446	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
701347009447	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347009448	putative DNA binding site [nucleotide binding]; other site
701347009449	putative Zn2+ binding site [ion binding]; other site
701347009450	AsnC family; Region: AsnC_trans_reg; pfam01037
701347009451	thioredoxin reductase; Provisional; Region: PRK10262
701347009452	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347009453	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347009454	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
701347009455	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
701347009456	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009457	Walker A/P-loop; other site
701347009458	ATP binding site [chemical binding]; other site
701347009459	Q-loop/lid; other site
701347009460	ABC transporter signature motif; other site
701347009461	Walker B; other site
701347009462	D-loop; other site
701347009463	H-loop/switch region; other site
701347009464	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
701347009465	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
701347009466	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009467	Walker A/P-loop; other site
701347009468	ATP binding site [chemical binding]; other site
701347009469	Q-loop/lid; other site
701347009470	ABC transporter signature motif; other site
701347009471	Walker B; other site
701347009472	D-loop; other site
701347009473	H-loop/switch region; other site
701347009474	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
701347009475	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
701347009476	rRNA binding site [nucleotide binding]; other site
701347009477	predicted 30S ribosome binding site; other site
701347009478	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
701347009479	Clp amino terminal domain; Region: Clp_N; pfam02861
701347009480	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347009481	Walker A motif; other site
701347009482	ATP binding site [chemical binding]; other site
701347009483	Walker B motif; other site
701347009484	arginine finger; other site
701347009485	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347009486	Walker A motif; other site
701347009487	ATP binding site [chemical binding]; other site
701347009488	Walker B motif; other site
701347009489	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
701347009490	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
701347009491	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
701347009492	DNA-binding site [nucleotide binding]; DNA binding site
701347009493	RNA-binding motif; other site
701347009494	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
701347009495	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
701347009496	Walker A/P-loop; other site
701347009497	ATP binding site [chemical binding]; other site
701347009498	Q-loop/lid; other site
701347009499	ABC transporter signature motif; other site
701347009500	Walker B; other site
701347009501	D-loop; other site
701347009502	H-loop/switch region; other site
701347009503	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
701347009504	FtsX-like permease family; Region: FtsX; pfam02687
701347009505	macrolide transporter subunit MacA; Provisional; Region: PRK11578
701347009506	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347009507	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347009508	Protein of unknown function (DUF535); Region: DUF535; pfam04393
701347009509	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
701347009510	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
701347009511	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
701347009512	putative active site [active]
701347009513	putative metal-binding site [ion binding]; other site
701347009514	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
701347009515	amphipathic channel; other site
701347009516	Asn-Pro-Ala signature motifs; other site
701347009517	Predicted membrane protein [Function unknown]; Region: COG2431
701347009518	hybrid cluster protein; Provisional; Region: PRK05290
701347009519	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347009520	ACS interaction site; other site
701347009521	CODH interaction site; other site
701347009522	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
701347009523	hybrid metal cluster; other site
701347009524	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
701347009525	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
701347009526	FAD binding pocket [chemical binding]; other site
701347009527	conserved FAD binding motif [chemical binding]; other site
701347009528	phosphate binding motif [ion binding]; other site
701347009529	beta-alpha-beta structure motif; other site
701347009530	NAD binding pocket [chemical binding]; other site
701347009531	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
701347009532	catalytic loop [active]
701347009533	iron binding site [ion binding]; other site
701347009534	pyruvate dehydrogenase; Provisional; Region: PRK09124
701347009535	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
701347009536	PYR/PP interface [polypeptide binding]; other site
701347009537	dimer interface [polypeptide binding]; other site
701347009538	tetramer interface [polypeptide binding]; other site
701347009539	TPP binding site [chemical binding]; other site
701347009540	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347009541	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
701347009542	TPP-binding site [chemical binding]; other site
701347009543	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
701347009544	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
701347009545	tetramer interface [polypeptide binding]; other site
701347009546	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347009547	catalytic residue [active]
701347009548	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
701347009549	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
701347009550	putative NAD(P) binding site [chemical binding]; other site
701347009551	putative active site [active]
701347009552	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
701347009553	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
701347009554	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
701347009555	NAD(P) binding site [chemical binding]; other site
701347009556	active site
701347009557	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
701347009558	potassium uptake protein; Region: kup; TIGR00794
701347009559	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
701347009560	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
701347009561	putative sugar binding site [chemical binding]; other site
701347009562	catalytic residues [active]
701347009563	PKD domain; Region: PKD; pfam00801
701347009564	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
701347009565	aromatic chitin/cellulose binding site residues [chemical binding]; other site
701347009566	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
701347009567	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347009568	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347009569	catalytic residue [active]
701347009570	N-terminal Early set domain associated with the catalytic domain of chitinase; Region: E_set_Chitinase_N; cd02848
701347009571	Glyco_18 domain; Region: Glyco_18; smart00636
701347009572	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
701347009573	active site
701347009574	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
701347009575	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
701347009576	aromatic chitin/cellulose binding site residues [chemical binding]; other site
701347009577	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
701347009578	aromatic chitin/cellulose binding site residues [chemical binding]; other site
701347009579	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
701347009580	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
701347009581	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
701347009582	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
701347009583	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
701347009584	GspL periplasmic domain; Region: GspL_C; cl14909
701347009585	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
701347009586	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
701347009587	type II secretion system protein J; Region: gspJ; TIGR01711
701347009588	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
701347009589	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
701347009590	type II secretion system protein I; Region: gspI; TIGR01707
701347009591	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
701347009592	type II secretion system protein H; Region: typeII_sec_gspH; TIGR01708
701347009593	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
701347009594	Type II transport protein GspH; Region: GspH; pfam12019
701347009595	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
701347009596	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
701347009597	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
701347009598	type II secretion system protein F; Region: GspF; TIGR02120
701347009599	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
701347009600	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
701347009601	type II secretion system protein E; Region: type_II_gspE; TIGR02533
701347009602	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
701347009603	Walker A motif; other site
701347009604	ATP binding site [chemical binding]; other site
701347009605	Walker B motif; other site
701347009606	type II secretion system protein D; Region: type_II_gspD; TIGR02517
701347009607	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
701347009608	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
701347009609	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
701347009610	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
701347009611	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
701347009612	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
701347009613	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
701347009614	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
701347009615	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
701347009616	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
701347009617	amidase catalytic site [active]
701347009618	Zn binding residues [ion binding]; other site
701347009619	substrate binding site [chemical binding]; other site
701347009620	hypothetical protein; Provisional; Region: PRK02877
701347009621	putative lipoprotein; Provisional; Region: PRK10533
701347009622	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
701347009623	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009624	Walker A/P-loop; other site
701347009625	ATP binding site [chemical binding]; other site
701347009626	Q-loop/lid; other site
701347009627	ABC transporter signature motif; other site
701347009628	Walker B; other site
701347009629	D-loop; other site
701347009630	H-loop/switch region; other site
701347009631	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
701347009632	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347009633	substrate binding pocket [chemical binding]; other site
701347009634	membrane-bound complex binding site; other site
701347009635	hinge residues; other site
701347009636	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347009637	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009638	dimer interface [polypeptide binding]; other site
701347009639	conserved gate region; other site
701347009640	putative PBP binding loops; other site
701347009641	ABC-ATPase subunit interface; other site
701347009642	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009643	dimer interface [polypeptide binding]; other site
701347009644	conserved gate region; other site
701347009645	putative PBP binding loops; other site
701347009646	ABC-ATPase subunit interface; other site
701347009647	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
701347009648	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347009649	substrate binding pocket [chemical binding]; other site
701347009650	membrane-bound complex binding site; other site
701347009651	hinge residues; other site
701347009652	Predicted transcriptional regulator [Transcription]; Region: COG2944
701347009653	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
701347009654	non-specific DNA binding site [nucleotide binding]; other site
701347009655	salt bridge; other site
701347009656	sequence-specific DNA binding site [nucleotide binding]; other site
701347009657	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347009658	dimer interface [polypeptide binding]; other site
701347009659	phosphorylation site [posttranslational modification]
701347009660	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347009661	ATP binding site [chemical binding]; other site
701347009662	Mg2+ binding site [ion binding]; other site
701347009663	G-X-G motif; other site
701347009664	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
701347009665	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347009666	active site
701347009667	phosphorylation site [posttranslational modification]
701347009668	intermolecular recognition site; other site
701347009669	dimerization interface [polypeptide binding]; other site
701347009670	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347009671	DNA binding site [nucleotide binding]
701347009672	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
701347009673	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
701347009674	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
701347009675	Moco binding site; other site
701347009676	metal coordination site [ion binding]; other site
701347009677	Fimbrial protein; Region: Fimbrial; cl01416
701347009678	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
701347009679	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347009680	S-adenosylmethionine binding site [chemical binding]; other site
701347009681	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
701347009682	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
701347009683	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009684	dimer interface [polypeptide binding]; other site
701347009685	conserved gate region; other site
701347009686	putative PBP binding loops; other site
701347009687	ABC-ATPase subunit interface; other site
701347009688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009689	dimer interface [polypeptide binding]; other site
701347009690	conserved gate region; other site
701347009691	putative PBP binding loops; other site
701347009692	ABC-ATPase subunit interface; other site
701347009693	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
701347009694	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009695	Walker A/P-loop; other site
701347009696	ATP binding site [chemical binding]; other site
701347009697	Q-loop/lid; other site
701347009698	ABC transporter signature motif; other site
701347009699	Walker B; other site
701347009700	D-loop; other site
701347009701	H-loop/switch region; other site
701347009702	TOBE domain; Region: TOBE_2; pfam08402
701347009703	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
701347009704	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
701347009705	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
701347009706	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
701347009707	RimK-like ATP-grasp domain; Region: RimK; pfam08443
701347009708	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
701347009709	dimer interface [polypeptide binding]; other site
701347009710	FMN binding site [chemical binding]; other site
701347009711	NADPH bind site [chemical binding]; other site
701347009712	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
701347009713	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
701347009714	GSH binding site [chemical binding]; other site
701347009715	catalytic residues [active]
701347009716	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
701347009717	putative transporter; Provisional; Region: PRK04972
701347009718	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
701347009719	TrkA-C domain; Region: TrkA_C; pfam02080
701347009720	TrkA-C domain; Region: TrkA_C; pfam02080
701347009721	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
701347009722	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
701347009723	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347009724	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347009725	putative substrate translocation pore; other site
701347009726	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347009727	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
701347009728	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
701347009729	active site
701347009730	motif I; other site
701347009731	motif II; other site
701347009732	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
701347009733	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
701347009734	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347009735	putative substrate translocation pore; other site
701347009736	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
701347009737	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
701347009738	active site
701347009739	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
701347009740	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
701347009741	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347009742	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
701347009743	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
701347009744	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
701347009745	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
701347009746	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
701347009747	putative C-terminal domain interface [polypeptide binding]; other site
701347009748	putative GSH binding site (G-site) [chemical binding]; other site
701347009749	putative dimer interface [polypeptide binding]; other site
701347009750	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
701347009751	putative N-terminal domain interface [polypeptide binding]; other site
701347009752	putative dimer interface [polypeptide binding]; other site
701347009753	putative substrate binding pocket (H-site) [chemical binding]; other site
701347009754	Biofilm formation protein (YliH/bssR); Region: YliH; cl08211
701347009755	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
701347009756	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
701347009757	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
701347009758	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347009759	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347009760	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347009761	dimerization interface [polypeptide binding]; other site
701347009762	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
701347009763	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
701347009764	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
701347009765	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347009766	FeS/SAM binding site; other site
701347009767	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
701347009768	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
701347009769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009770	dimer interface [polypeptide binding]; other site
701347009771	conserved gate region; other site
701347009772	putative PBP binding loops; other site
701347009773	ABC-ATPase subunit interface; other site
701347009774	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
701347009775	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009776	dimer interface [polypeptide binding]; other site
701347009777	conserved gate region; other site
701347009778	putative PBP binding loops; other site
701347009779	ABC-ATPase subunit interface; other site
701347009780	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
701347009781	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
701347009782	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
701347009783	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347009784	Walker A/P-loop; other site
701347009785	ATP binding site [chemical binding]; other site
701347009786	Q-loop/lid; other site
701347009787	ABC transporter signature motif; other site
701347009788	Walker B; other site
701347009789	D-loop; other site
701347009790	H-loop/switch region; other site
701347009791	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
701347009792	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347009793	Walker A/P-loop; other site
701347009794	ATP binding site [chemical binding]; other site
701347009795	Q-loop/lid; other site
701347009796	ABC transporter signature motif; other site
701347009797	Walker B; other site
701347009798	D-loop; other site
701347009799	H-loop/switch region; other site
701347009800	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
701347009801	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
701347009802	catalytic nucleophile [active]
701347009803	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
701347009804	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
701347009805	dimer interface [polypeptide binding]; other site
701347009806	putative functional site; other site
701347009807	putative MPT binding site; other site
701347009808	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
701347009809	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
701347009810	ATP binding site [chemical binding]; other site
701347009811	substrate interface [chemical binding]; other site
701347009812	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
701347009813	active site
701347009814	intersubunit interactions; other site
701347009815	catalytic residue [active]
701347009816	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
701347009817	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347009818	FeS/SAM binding site; other site
701347009819	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
701347009820	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
701347009821	dimer interface [polypeptide binding]; other site
701347009822	active site
701347009823	glycine loop; other site
701347009824	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
701347009825	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347009826	active site
701347009827	motif I; other site
701347009828	motif II; other site
701347009829	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347009830	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
701347009831	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347009832	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347009833	DNA binding site [nucleotide binding]
701347009834	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
701347009835	ligand binding site [chemical binding]; other site
701347009836	dimerization interface [polypeptide binding]; other site
701347009837	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347009838	D-galactonate transporter; Region: 2A0114; TIGR00893
701347009839	putative substrate translocation pore; other site
701347009840	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
701347009841	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
701347009842	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
701347009843	putative active site [active]
701347009844	putative catalytic site [active]
701347009845	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
701347009846	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347009847	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347009848	Walker A/P-loop; other site
701347009849	ATP binding site [chemical binding]; other site
701347009850	Q-loop/lid; other site
701347009851	ABC transporter signature motif; other site
701347009852	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347009853	Walker B; other site
701347009854	D-loop; other site
701347009855	ABC transporter; Region: ABC_tran_2; pfam12848
701347009856	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347009857	L,D-transpeptidase; Provisional; Region: PRK10260
701347009858	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347009859	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
701347009860	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347009861	DNA-binding site [nucleotide binding]; DNA binding site
701347009862	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
701347009863	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
701347009864	beta-galactosidase; Region: BGL; TIGR03356
701347009865	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
701347009866	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
701347009867	transmembrane helices; other site
701347009868	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
701347009869	manganese transport regulator MntR; Provisional; Region: PRK11050
701347009870	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
701347009871	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
701347009872	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
701347009873	Sulfatase; Region: Sulfatase; pfam00884
701347009874	outer membrane protein X; Provisional; Region: ompX; PRK09408
701347009875	threonine and homoserine efflux system; Provisional; Region: PRK10532
701347009876	EamA-like transporter family; Region: EamA; pfam00892
701347009877	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
701347009878	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
701347009879	dimerization interface [polypeptide binding]; other site
701347009880	DPS ferroxidase diiron center [ion binding]; other site
701347009881	ion pore; other site
701347009882	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
701347009883	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347009884	substrate binding pocket [chemical binding]; other site
701347009885	membrane-bound complex binding site; other site
701347009886	hinge residues; other site
701347009887	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347009888	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347009889	dimer interface [polypeptide binding]; other site
701347009890	conserved gate region; other site
701347009891	putative PBP binding loops; other site
701347009892	ABC-ATPase subunit interface; other site
701347009893	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
701347009894	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347009895	Walker A/P-loop; other site
701347009896	ATP binding site [chemical binding]; other site
701347009897	Q-loop/lid; other site
701347009898	ABC transporter signature motif; other site
701347009899	Walker B; other site
701347009900	D-loop; other site
701347009901	H-loop/switch region; other site
701347009902	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
701347009903	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
701347009904	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
701347009905	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347009906	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
701347009907	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
701347009908	cryptic adenine deaminase; Provisional; Region: PRK10027
701347009909	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
701347009910	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
701347009911	active site
701347009912	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
701347009913	glycosyl transferase family protein; Provisional; Region: PRK08136
701347009914	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
701347009915	Fimbrial protein; Region: Fimbrial; cl01416
701347009916	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
701347009917	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347009918	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347009919	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347009920	PapC N-terminal domain; Region: PapC_N; pfam13954
701347009921	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347009922	PapC C-terminal domain; Region: PapC_C; pfam13953
701347009923	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347009924	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
701347009925	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
701347009926	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
701347009927	DEAD_2; Region: DEAD_2; pfam06733
701347009928	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
701347009929	helicase 45; Provisional; Region: PTZ00424
701347009930	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
701347009931	ATP binding site [chemical binding]; other site
701347009932	Mg++ binding site [ion binding]; other site
701347009933	motif III; other site
701347009934	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347009935	nucleotide binding region [chemical binding]; other site
701347009936	ATP-binding site [chemical binding]; other site
701347009937	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
701347009938	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347009939	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
701347009940	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
701347009941	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347009942	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347009943	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
701347009944	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
701347009945	Walker A/P-loop; other site
701347009946	ATP binding site [chemical binding]; other site
701347009947	Q-loop/lid; other site
701347009948	ABC transporter signature motif; other site
701347009949	Walker B; other site
701347009950	D-loop; other site
701347009951	H-loop/switch region; other site
701347009952	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
701347009953	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
701347009954	Walker A/P-loop; other site
701347009955	ATP binding site [chemical binding]; other site
701347009956	Q-loop/lid; other site
701347009957	ABC transporter signature motif; other site
701347009958	Walker B; other site
701347009959	D-loop; other site
701347009960	H-loop/switch region; other site
701347009961	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
701347009962	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
701347009963	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
701347009964	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
701347009965	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
701347009966	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
701347009967	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
701347009968	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
701347009969	MoaE homodimer interface [polypeptide binding]; other site
701347009970	MoaD interaction [polypeptide binding]; other site
701347009971	active site residues [active]
701347009972	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
701347009973	MoaE interaction surface [polypeptide binding]; other site
701347009974	MoeB interaction surface [polypeptide binding]; other site
701347009975	thiocarboxylated glycine; other site
701347009976	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
701347009977	trimer interface [polypeptide binding]; other site
701347009978	dimer interface [polypeptide binding]; other site
701347009979	putative active site [active]
701347009980	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
701347009981	MPT binding site; other site
701347009982	trimer interface [polypeptide binding]; other site
701347009983	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
701347009984	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347009985	FeS/SAM binding site; other site
701347009986	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
701347009987	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
701347009988	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
701347009989	phosphate binding site [ion binding]; other site
701347009990	putative substrate binding pocket [chemical binding]; other site
701347009991	dimer interface [polypeptide binding]; other site
701347009992	putative metal dependent hydrolase; Provisional; Region: PRK11598
701347009993	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
701347009994	Sulfatase; Region: Sulfatase; pfam00884
701347009995	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
701347009996	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347009997	active site
701347009998	phosphorylation site [posttranslational modification]
701347009999	intermolecular recognition site; other site
701347010000	dimerization interface [polypeptide binding]; other site
701347010001	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347010002	DNA binding site [nucleotide binding]
701347010003	sensor protein BasS/PmrB; Provisional; Region: PRK10755
701347010004	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347010005	dimer interface [polypeptide binding]; other site
701347010006	phosphorylation site [posttranslational modification]
701347010007	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347010008	ATP binding site [chemical binding]; other site
701347010009	G-X-G motif; other site
701347010010	excinuclease ABC subunit B; Provisional; Region: PRK05298
701347010011	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347010012	ATP binding site [chemical binding]; other site
701347010013	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347010014	nucleotide binding region [chemical binding]; other site
701347010015	ATP-binding site [chemical binding]; other site
701347010016	Ultra-violet resistance protein B; Region: UvrB; pfam12344
701347010017	UvrB/uvrC motif; Region: UVR; pfam02151
701347010018	AAA domain; Region: AAA_26; pfam13500
701347010019	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
701347010020	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
701347010021	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
701347010022	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347010023	S-adenosylmethionine binding site [chemical binding]; other site
701347010024	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
701347010025	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
701347010026	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347010027	catalytic residue [active]
701347010028	biotin synthase; Provisional; Region: PRK15108
701347010029	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347010030	FeS/SAM binding site; other site
701347010031	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
701347010032	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
701347010033	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347010034	inhibitor-cofactor binding pocket; inhibition site
701347010035	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347010036	catalytic residue [active]
701347010037	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
701347010038	substrate binding site [chemical binding]; other site
701347010039	putative proline-specific permease; Provisional; Region: proY; PRK10580
701347010040	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
701347010041	active sites [active]
701347010042	tetramer interface [polypeptide binding]; other site
701347010043	urocanate hydratase; Provisional; Region: PRK05414
701347010044	Protein of unknown function DUF115; Region: MAF_flag10; cl17471
701347010045	histidine utilization repressor; Provisional; Region: PRK14999
701347010046	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347010047	DNA-binding site [nucleotide binding]; DNA binding site
701347010048	UTRA domain; Region: UTRA; pfam07702
701347010049	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
701347010050	putative active site [active]
701347010051	putative metal binding site [ion binding]; other site
701347010052	imidazolonepropionase; Validated; Region: PRK09356
701347010053	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
701347010054	active site
701347010055	acyl-CoA thioesterase; Provisional; Region: PRK10531
701347010056	putative pectinesterase; Region: PLN02432; cl01911
701347010057	Thiol-activated cytolysin; Region: Thiol_cytolysin; pfam01289
701347010058	6-phosphogluconolactonase; Provisional; Region: PRK11028
701347010059	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
701347010060	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347010061	active site
701347010062	motif I; other site
701347010063	motif II; other site
701347010064	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347010065	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
701347010066	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347010067	Walker A/P-loop; other site
701347010068	ATP binding site [chemical binding]; other site
701347010069	Q-loop/lid; other site
701347010070	ABC transporter signature motif; other site
701347010071	Walker B; other site
701347010072	D-loop; other site
701347010073	H-loop/switch region; other site
701347010074	molybdenum-pterin binding domain; Region: Mop; TIGR00638
701347010075	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
701347010076	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347010077	dimer interface [polypeptide binding]; other site
701347010078	conserved gate region; other site
701347010079	putative PBP binding loops; other site
701347010080	ABC-ATPase subunit interface; other site
701347010081	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
701347010082	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347010083	substrate binding pocket [chemical binding]; other site
701347010084	membrane-bound complex binding site; other site
701347010085	hinge residues; other site
701347010086	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
701347010087	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
701347010088	dimer interface [polypeptide binding]; other site
701347010089	ligand binding site [chemical binding]; other site
701347010090	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347010091	dimerization interface [polypeptide binding]; other site
701347010092	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347010093	dimer interface [polypeptide binding]; other site
701347010094	putative CheW interface [polypeptide binding]; other site
701347010095	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
701347010096	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
701347010097	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
701347010098	TOBE domain; Region: TOBE; cl01440
701347010099	TOBE domain; Region: TOBE; pfam03459
701347010100	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
701347010101	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347010102	Walker A/P-loop; other site
701347010103	ATP binding site [chemical binding]; other site
701347010104	Q-loop/lid; other site
701347010105	ABC transporter signature motif; other site
701347010106	Walker B; other site
701347010107	D-loop; other site
701347010108	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347010109	Walker A/P-loop; other site
701347010110	ATP binding site [chemical binding]; other site
701347010111	Q-loop/lid; other site
701347010112	ABC transporter signature motif; other site
701347010113	Walker B; other site
701347010114	D-loop; other site
701347010115	H-loop/switch region; other site
701347010116	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
701347010117	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
701347010118	NAD binding site [chemical binding]; other site
701347010119	homodimer interface [polypeptide binding]; other site
701347010120	active site
701347010121	substrate binding site [chemical binding]; other site
701347010122	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
701347010123	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
701347010124	dimer interface [polypeptide binding]; other site
701347010125	active site
701347010126	galactokinase; Provisional; Region: PRK05101
701347010127	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
701347010128	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
701347010129	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
701347010130	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
701347010131	active site
701347010132	catalytic residues [active]
701347010133	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
701347010134	catalytic core [active]
701347010135	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
701347010136	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
701347010137	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
701347010138	Cation efflux family; Region: Cation_efflux; cl00316
701347010139	quinolinate synthetase; Provisional; Region: PRK09375
701347010140	tol-pal system protein YbgF; Provisional; Region: PRK10803
701347010141	Tetratricopeptide repeat; Region: TPR_6; pfam13174
701347010142	Tetratricopeptide repeat; Region: TPR_6; pfam13174
701347010143	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
701347010144	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347010145	ligand binding site [chemical binding]; other site
701347010146	translocation protein TolB; Provisional; Region: tolB; PRK03629
701347010147	TolB amino-terminal domain; Region: TolB_N; pfam04052
701347010148	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
701347010149	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
701347010150	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
701347010151	TolA C-terminal; Region: TolA; pfam06519
701347010152	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
701347010153	colicin uptake protein TolR; Provisional; Region: PRK11024
701347010154	colicin uptake protein TolQ; Provisional; Region: PRK10801
701347010155	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
701347010156	active site
701347010157	hypothetical protein; Provisional; Region: PRK10588
701347010158	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
701347010159	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
701347010160	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
701347010161	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
701347010162	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
701347010163	alpha-mannosidase; Provisional; Region: PRK09819
701347010164	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
701347010165	active site
701347010166	metal binding site [ion binding]; metal-binding site
701347010167	catalytic site [active]
701347010168	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
701347010169	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
701347010170	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347010171	active site
701347010172	phosphorylation site [posttranslational modification]
701347010173	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
701347010174	active site
701347010175	P-loop; other site
701347010176	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
701347010177	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
701347010178	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347010179	DNA-binding site [nucleotide binding]; DNA binding site
701347010180	UTRA domain; Region: UTRA; pfam07702
701347010181	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
701347010182	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347010183	D-galactonate transporter; Region: 2A0114; TIGR00893
701347010184	putative substrate translocation pore; other site
701347010185	Alginate lyase; Region: Alginate_lyase; pfam05426
701347010186	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
701347010187	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
701347010188	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
701347010189	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
701347010190	CoA binding domain; Region: CoA_binding; smart00881
701347010191	CoA-ligase; Region: Ligase_CoA; pfam00549
701347010192	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
701347010193	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
701347010194	CoA-ligase; Region: Ligase_CoA; pfam00549
701347010195	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
701347010196	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
701347010197	E3 interaction surface; other site
701347010198	lipoyl attachment site [posttranslational modification]; other site
701347010199	e3 binding domain; Region: E3_binding; pfam02817
701347010200	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
701347010201	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
701347010202	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
701347010203	TPP-binding site [chemical binding]; other site
701347010204	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
701347010205	dimer interface [polypeptide binding]; other site
701347010206	PYR/PP interface [polypeptide binding]; other site
701347010207	TPP binding site [chemical binding]; other site
701347010208	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
701347010209	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
701347010210	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
701347010211	L-aspartate oxidase; Provisional; Region: PRK06175
701347010212	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
701347010213	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
701347010214	SdhC subunit interface [polypeptide binding]; other site
701347010215	proximal heme binding site [chemical binding]; other site
701347010216	cardiolipin binding site; other site
701347010217	Iron-sulfur protein interface; other site
701347010218	proximal quinone binding site [chemical binding]; other site
701347010219	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
701347010220	Iron-sulfur protein interface; other site
701347010221	proximal quinone binding site [chemical binding]; other site
701347010222	SdhD (CybS) interface [polypeptide binding]; other site
701347010223	proximal heme binding site [chemical binding]; other site
701347010224	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
701347010225	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
701347010226	dimer interface [polypeptide binding]; other site
701347010227	active site
701347010228	citrylCoA binding site [chemical binding]; other site
701347010229	NADH binding [chemical binding]; other site
701347010230	cationic pore residues; other site
701347010231	oxalacetate/citrate binding site [chemical binding]; other site
701347010232	coenzyme A binding site [chemical binding]; other site
701347010233	catalytic triad [active]
701347010234	endonuclease VIII; Provisional; Region: PRK10445
701347010235	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
701347010236	DNA binding site [nucleotide binding]
701347010237	catalytic residue [active]
701347010238	putative catalytic residues [active]
701347010239	H2TH interface [polypeptide binding]; other site
701347010240	intercalation triad [nucleotide binding]; other site
701347010241	substrate specificity determining residue; other site
701347010242	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
701347010243	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
701347010244	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
701347010245	putative substrate binding pocket [chemical binding]; other site
701347010246	AC domain interface; other site
701347010247	catalytic triad [active]
701347010248	AB domain interface; other site
701347010249	Predicted membrane protein [Function unknown]; Region: COG3817
701347010250	Protein of unknown function (DUF979); Region: DUF979; pfam06166
701347010251	Protein of unknown function (DUF969); Region: DUF969; pfam06149
701347010252	LamB/YcsF family protein; Provisional; Region: PRK05406
701347010253	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
701347010254	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
701347010255	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
701347010256	Uncharacterized conserved protein [Function unknown]; Region: COG0327
701347010257	metal-binding protein; Provisional; Region: PRK10799
701347010258	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
701347010259	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347010260	putative substrate translocation pore; other site
701347010261	POT family; Region: PTR2; pfam00854
701347010262	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
701347010263	DNA photolyase; Region: DNA_photolyase; pfam00875
701347010264	Protein of unknown function (DUF523); Region: DUF523; pfam04463
701347010265	Uncharacterized conserved protein [Function unknown]; Region: COG3272
701347010266	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
701347010267	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
701347010268	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
701347010269	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
701347010270	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347010271	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
701347010272	sensor protein KdpD; Provisional; Region: PRK10490
701347010273	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
701347010274	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
701347010275	Ligand Binding Site [chemical binding]; other site
701347010276	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
701347010277	GAF domain; Region: GAF_3; pfam13492
701347010278	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347010279	dimer interface [polypeptide binding]; other site
701347010280	phosphorylation site [posttranslational modification]
701347010281	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347010282	ATP binding site [chemical binding]; other site
701347010283	Mg2+ binding site [ion binding]; other site
701347010284	G-X-G motif; other site
701347010285	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
701347010286	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347010287	active site
701347010288	phosphorylation site [posttranslational modification]
701347010289	intermolecular recognition site; other site
701347010290	dimerization interface [polypeptide binding]; other site
701347010291	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347010292	DNA binding site [nucleotide binding]
701347010293	ornithine decarboxylase; Provisional; Region: PRK13578
701347010294	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
701347010295	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
701347010296	homodimer interface [polypeptide binding]; other site
701347010297	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347010298	catalytic residue [active]
701347010299	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
701347010300	putrescine transporter; Provisional; Region: potE; PRK10655
701347010301	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
701347010302	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
701347010303	phosphoglucomutase; Validated; Region: PRK07564
701347010304	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
701347010305	active site
701347010306	substrate binding site [chemical binding]; other site
701347010307	metal binding site [ion binding]; metal-binding site
701347010308	replication initiation regulator SeqA; Provisional; Region: PRK11187
701347010309	acyl-CoA esterase; Provisional; Region: PRK10673
701347010310	PGAP1-like protein; Region: PGAP1; pfam07819
701347010311	LexA regulated protein; Provisional; Region: PRK11675
701347010312	flavodoxin FldA; Validated; Region: PRK09267
701347010313	ferric uptake regulator; Provisional; Region: fur; PRK09462
701347010314	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
701347010315	metal binding site 2 [ion binding]; metal-binding site
701347010316	putative DNA binding helix; other site
701347010317	metal binding site 1 [ion binding]; metal-binding site
701347010318	dimer interface [polypeptide binding]; other site
701347010319	structural Zn2+ binding site [ion binding]; other site
701347010320	YbfN-like lipoprotein; Region: YbfN; pfam13982
701347010321	outer membrane porin, OprD family; Region: OprD; pfam03573
701347010322	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
701347010323	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
701347010324	active site
701347010325	HIGH motif; other site
701347010326	nucleotide binding site [chemical binding]; other site
701347010327	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
701347010328	KMSKS motif; other site
701347010329	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
701347010330	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347010331	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
701347010332	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347010333	active site turn [active]
701347010334	phosphorylation site [posttranslational modification]
701347010335	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
701347010336	HPr interaction site; other site
701347010337	glycerol kinase (GK) interaction site [polypeptide binding]; other site
701347010338	active site
701347010339	phosphorylation site [posttranslational modification]
701347010340	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
701347010341	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
701347010342	active site
701347010343	trimer interface [polypeptide binding]; other site
701347010344	allosteric site; other site
701347010345	active site lid [active]
701347010346	hexamer (dimer of trimers) interface [polypeptide binding]; other site
701347010347	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
701347010348	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
701347010349	active site
701347010350	dimer interface [polypeptide binding]; other site
701347010351	MarR family; Region: MarR; pfam01047
701347010352	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
701347010353	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347010354	nucleotide binding site [chemical binding]; other site
701347010355	UMP phosphatase; Provisional; Region: PRK10444
701347010356	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347010357	active site
701347010358	motif I; other site
701347010359	motif II; other site
701347010360	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347010361	asparagine synthetase B; Provisional; Region: asnB; PRK09431
701347010362	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
701347010363	active site
701347010364	dimer interface [polypeptide binding]; other site
701347010365	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
701347010366	Ligand Binding Site [chemical binding]; other site
701347010367	Molecular Tunnel; other site
701347010368	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
701347010369	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
701347010370	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
701347010371	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
701347010372	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347010373	FeS/SAM binding site; other site
701347010374	TRAM domain; Region: TRAM; pfam01938
701347010375	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
701347010376	PhoH-like protein; Region: PhoH; pfam02562
701347010377	metal-binding heat shock protein; Provisional; Region: PRK00016
701347010378	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
701347010379	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
701347010380	Transporter associated domain; Region: CorC_HlyC; smart01091
701347010381	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
701347010382	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
701347010383	putative active site [active]
701347010384	catalytic triad [active]
701347010385	putative dimer interface [polypeptide binding]; other site
701347010386	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
701347010387	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347010388	substrate binding pocket [chemical binding]; other site
701347010389	membrane-bound complex binding site; other site
701347010390	hinge residues; other site
701347010391	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347010392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347010393	dimer interface [polypeptide binding]; other site
701347010394	conserved gate region; other site
701347010395	putative PBP binding loops; other site
701347010396	ABC-ATPase subunit interface; other site
701347010397	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
701347010398	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347010399	dimer interface [polypeptide binding]; other site
701347010400	conserved gate region; other site
701347010401	putative PBP binding loops; other site
701347010402	ABC-ATPase subunit interface; other site
701347010403	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
701347010404	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347010405	Walker A/P-loop; other site
701347010406	ATP binding site [chemical binding]; other site
701347010407	Q-loop/lid; other site
701347010408	ABC transporter signature motif; other site
701347010409	Walker B; other site
701347010410	D-loop; other site
701347010411	H-loop/switch region; other site
701347010412	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
701347010413	active site
701347010414	tetramer interface [polypeptide binding]; other site
701347010415	hypothetical protein; Provisional; Region: PRK11032
701347010416	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993
701347010417	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
701347010418	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
701347010419	HIGH motif; other site
701347010420	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
701347010421	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
701347010422	active site
701347010423	KMSKS motif; other site
701347010424	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
701347010425	tRNA binding surface [nucleotide binding]; other site
701347010426	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
701347010427	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
701347010428	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
701347010429	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
701347010430	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
701347010431	active site
701347010432	(T/H)XGH motif; other site
701347010433	ribosome-associated protein; Provisional; Region: PRK11538
701347010434	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
701347010435	penicillin-binding protein 2; Provisional; Region: PRK10795
701347010436	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
701347010437	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
701347010438	cell wall shape-determining protein; Provisional; Region: PRK10794
701347010439	rare lipoprotein A; Provisional; Region: PRK10672
701347010440	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
701347010441	Sporulation related domain; Region: SPOR; pfam05036
701347010442	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
701347010443	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
701347010444	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
701347010445	hypothetical protein; Provisional; Region: PRK04998
701347010446	lipoate-protein ligase B; Provisional; Region: PRK14342
701347010447	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
701347010448	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347010449	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
701347010450	substrate binding pocket [chemical binding]; other site
701347010451	dimerization interface [polypeptide binding]; other site
701347010452	lipoyl synthase; Provisional; Region: PRK05481
701347010453	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347010454	FeS/SAM binding site; other site
701347010455	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
701347010456	Predicted amidohydrolase [General function prediction only]; Region: COG0388
701347010457	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
701347010458	putative active site [active]
701347010459	catalytic triad [active]
701347010460	putative dimer interface [polypeptide binding]; other site
701347010461	chromosome condensation membrane protein; Provisional; Region: PRK14196
701347010462	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
701347010463	DNA-binding site [nucleotide binding]; DNA binding site
701347010464	RNA-binding motif; other site
701347010465	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
701347010466	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
701347010467	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
701347010468	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
701347010469	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
701347010470	putative active site [active]
701347010471	(T/H)XGH motif; other site
701347010472	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
701347010473	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
701347010474	transmembrane helices; other site
701347010475	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
701347010476	B1 nucleotide binding pocket [chemical binding]; other site
701347010477	B2 nucleotide binding pocket [chemical binding]; other site
701347010478	CAS motifs; other site
701347010479	active site
701347010480	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
701347010481	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
701347010482	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
701347010483	Ligand Binding Site [chemical binding]; other site
701347010484	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
701347010485	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
701347010486	catalytic residue [active]
701347010487	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
701347010488	catalytic residues [active]
701347010489	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347010490	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347010491	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
701347010492	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
701347010493	dimer interface [polypeptide binding]; other site
701347010494	decamer (pentamer of dimers) interface [polypeptide binding]; other site
701347010495	catalytic triad [active]
701347010496	peroxidatic and resolving cysteines [active]
701347010497	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
701347010498	catalytic residues [active]
701347010499	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
701347010500	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347010501	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347010502	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
701347010503	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
701347010504	Active Sites [active]
701347010505	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
701347010506	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
701347010507	ParB-like nuclease domain; Region: ParB; smart00470
701347010508	methionine aminotransferase; Validated; Region: PRK09082
701347010509	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347010510	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347010511	homodimer interface [polypeptide binding]; other site
701347010512	catalytic residue [active]
701347010513	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
701347010514	intersubunit interface [polypeptide binding]; other site
701347010515	active site
701347010516	Zn2+ binding site [ion binding]; other site
701347010517	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
701347010518	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
701347010519	motif II; other site
701347010520	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
701347010521	Cupin domain; Region: Cupin_2; cl17218
701347010522	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347010523	non-specific DNA binding site [nucleotide binding]; other site
701347010524	salt bridge; other site
701347010525	sequence-specific DNA binding site [nucleotide binding]; other site
701347010526	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
701347010527	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
701347010528	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
701347010529	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
701347010530	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
701347010531	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347010532	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347010533	salt bridge; other site
701347010534	non-specific DNA binding site [nucleotide binding]; other site
701347010535	sequence-specific DNA binding site [nucleotide binding]; other site
701347010536	Uncharacterized small protein [Function unknown]; Region: COG2879
701347010537	carbon starvation protein A; Provisional; Region: PRK15015
701347010538	Carbon starvation protein CstA; Region: CstA; pfam02554
701347010539	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
701347010540	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
701347010541	CoenzymeA binding site [chemical binding]; other site
701347010542	subunit interaction site [polypeptide binding]; other site
701347010543	PHB binding site; other site
701347010544	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
701347010545	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
701347010546	NAD(P) binding site [chemical binding]; other site
701347010547	active site
701347010548	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
701347010549	hydrophobic substrate binding pocket; other site
701347010550	Isochorismatase family; Region: Isochorismatase; pfam00857
701347010551	active site
701347010552	conserved cis-peptide bond; other site
701347010553	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
701347010554	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
701347010555	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
701347010556	acyl-activating enzyme (AAE) consensus motif; other site
701347010557	active site
701347010558	AMP binding site [chemical binding]; other site
701347010559	substrate binding site [chemical binding]; other site
701347010560	isochorismate synthase EntC; Provisional; Region: PRK15016
701347010561	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
701347010562	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
701347010563	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
701347010564	siderophore binding site; other site
701347010565	enterobactin exporter EntS; Provisional; Region: PRK10489
701347010566	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347010567	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
701347010568	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347010569	ABC-ATPase subunit  interface; other site
701347010570	dimer interface [polypeptide binding]; other site
701347010571	putative PBP binding regions; other site
701347010572	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
701347010573	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347010574	ABC-ATPase subunit  interface; other site
701347010575	dimer interface [polypeptide binding]; other site
701347010576	putative PBP binding regions; other site
701347010577	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
701347010578	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
701347010579	Walker A/P-loop; other site
701347010580	ATP binding site [chemical binding]; other site
701347010581	Q-loop/lid; other site
701347010582	ABC transporter signature motif; other site
701347010583	Walker B; other site
701347010584	D-loop; other site
701347010585	H-loop/switch region; other site
701347010586	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
701347010587	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
701347010588	acyl-activating enzyme (AAE) consensus motif; other site
701347010589	AMP binding site [chemical binding]; other site
701347010590	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
701347010591	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
701347010592	MbtH-like protein; Region: MbtH; cl01279
701347010593	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
701347010594	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
701347010595	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
701347010596	outer membrane receptor FepA; Provisional; Region: PRK13524
701347010597	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347010598	N-terminal plug; other site
701347010599	ligand-binding site [chemical binding]; other site
701347010600	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
701347010601	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
701347010602	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347010603	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
701347010604	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
701347010605	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347010606	dimer interface [polypeptide binding]; other site
701347010607	conserved gate region; other site
701347010608	putative PBP binding loops; other site
701347010609	ABC-ATPase subunit interface; other site
701347010610	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
701347010611	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347010612	dimer interface [polypeptide binding]; other site
701347010613	conserved gate region; other site
701347010614	ABC-ATPase subunit interface; other site
701347010615	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
701347010616	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347010617	Walker A/P-loop; other site
701347010618	ATP binding site [chemical binding]; other site
701347010619	Q-loop/lid; other site
701347010620	ABC transporter signature motif; other site
701347010621	Walker B; other site
701347010622	D-loop; other site
701347010623	H-loop/switch region; other site
701347010624	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
701347010625	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347010626	Walker A/P-loop; other site
701347010627	ATP binding site [chemical binding]; other site
701347010628	Q-loop/lid; other site
701347010629	ABC transporter signature motif; other site
701347010630	Walker B; other site
701347010631	D-loop; other site
701347010632	H-loop/switch region; other site
701347010633	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
701347010634	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
701347010635	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347010636	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
701347010637	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347010638	motif II; other site
701347010639	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
701347010640	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
701347010641	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
701347010642	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347010643	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
701347010644	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
701347010645	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
701347010646	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347010647	Protein of unknown function (DUF419); Region: DUF419; cl15265
701347010648	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
701347010649	dimer interface [polypeptide binding]; other site
701347010650	FMN binding site [chemical binding]; other site
701347010651	Helix-turn-helix domain; Region: HTH_31; pfam13560
701347010652	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
701347010653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347010654	putative substrate translocation pore; other site
701347010655	phenylalanine transporter; Provisional; Region: PRK10249
701347010656	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
701347010657	Surface antigen; Region: Bac_surface_Ag; pfam01103
701347010658	Surface antigen; Region: Bac_surface_Ag; pfam01103
701347010659	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347010660	dimerization interface [polypeptide binding]; other site
701347010661	putative DNA binding site [nucleotide binding]; other site
701347010662	putative Zn2+ binding site [ion binding]; other site
701347010663	Predicted transporter component [General function prediction only]; Region: COG2391
701347010664	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
701347010665	Predicted transporter component [General function prediction only]; Region: COG2391
701347010666	Sulphur transport; Region: Sulf_transp; pfam04143
701347010667	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347010668	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347010669	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
701347010670	putative effector binding pocket; other site
701347010671	putative dimerization interface [polypeptide binding]; other site
701347010672	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347010673	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347010674	DNA binding residues [nucleotide binding]
701347010675	dimerization interface [polypeptide binding]; other site
701347010676	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
701347010677	Amino acid permease; Region: AA_permease_2; pfam13520
701347010678	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
701347010679	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
701347010680	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
701347010681	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
701347010682	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
701347010683	Chromate transporter; Region: Chromate_transp; pfam02417
701347010684	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
701347010685	metal coordination site [ion binding]; other site
701347010686	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347010687	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347010688	metal binding site [ion binding]; metal-binding site
701347010689	active site
701347010690	I-site; other site
701347010691	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347010692	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347010693	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347010694	active site
701347010695	catalytic tetrad [active]
701347010696	putative peptidase; Provisional; Region: PRK11649
701347010697	Peptidase family M23; Region: Peptidase_M23; pfam01551
701347010698	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
701347010699	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
701347010700	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347010701	Copper binding periplasmic protein CusF; Region: CusF_Ec; cl02363
701347010702	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
701347010703	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
701347010704	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347010705	active site
701347010706	phosphorylation site [posttranslational modification]
701347010707	intermolecular recognition site; other site
701347010708	dimerization interface [polypeptide binding]; other site
701347010709	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347010710	DNA binding site [nucleotide binding]
701347010711	sensor kinase CusS; Provisional; Region: PRK09835
701347010712	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347010713	dimerization interface [polypeptide binding]; other site
701347010714	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347010715	dimer interface [polypeptide binding]; other site
701347010716	phosphorylation site [posttranslational modification]
701347010717	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347010718	ATP binding site [chemical binding]; other site
701347010719	Mg2+ binding site [ion binding]; other site
701347010720	G-X-G motif; other site
701347010721	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347010722	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347010723	metal binding site [ion binding]; metal-binding site
701347010724	active site
701347010725	I-site; other site
701347010726	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
701347010727	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
701347010728	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
701347010729	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
701347010730	dimer interface [polypeptide binding]; other site
701347010731	active site
701347010732	metal binding site [ion binding]; metal-binding site
701347010733	Uncharacterized conserved protein [Function unknown]; Region: COG4095
701347010734	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
701347010735	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
701347010736	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
701347010737	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347010738	active site turn [active]
701347010739	phosphorylation site [posttranslational modification]
701347010740	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
701347010741	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
701347010742	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
701347010743	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
701347010744	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
701347010745	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347010746	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347010747	dimerization interface [polypeptide binding]; other site
701347010748	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
701347010749	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347010750	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347010751	alpha-galactosidase; Provisional; Region: PRK15076
701347010752	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
701347010753	NAD binding site [chemical binding]; other site
701347010754	sugar binding site [chemical binding]; other site
701347010755	divalent metal binding site [ion binding]; other site
701347010756	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
701347010757	dimer interface [polypeptide binding]; other site
701347010758	melibiose:sodium symporter; Provisional; Region: PRK10429
701347010759	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
701347010760	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
701347010761	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
701347010762	putative metal binding site [ion binding]; other site
701347010763	dimer interface [polypeptide binding]; other site
701347010764	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
701347010765	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
701347010766	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347010767	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347010768	dimerization interface [polypeptide binding]; other site
701347010769	transcriptional regulator FimZ; Provisional; Region: PRK09935
701347010770	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347010771	active site
701347010772	phosphorylation site [posttranslational modification]
701347010773	intermolecular recognition site; other site
701347010774	dimerization interface [polypeptide binding]; other site
701347010775	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347010776	DNA binding residues [nucleotide binding]
701347010777	dimerization interface [polypeptide binding]; other site
701347010778	Fimbrial protein; Region: Fimbrial; cl01416
701347010779	Fimbrial protein; Region: Fimbrial; cl01416
701347010780	outer membrane usher protein FimD; Provisional; Region: PRK15198
701347010781	PapC N-terminal domain; Region: PapC_N; pfam13954
701347010782	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347010783	PapC C-terminal domain; Region: PapC_C; pfam13953
701347010784	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347010785	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347010786	Fimbrial protein; Region: Fimbrial; cl01416
701347010787	Fimbrial protein; Region: Fimbrial; cl01416
701347010788	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
701347010789	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
701347010790	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
701347010791	homodimer interface [polypeptide binding]; other site
701347010792	NADP binding site [chemical binding]; other site
701347010793	substrate binding site [chemical binding]; other site
701347010794	ribosome-associated protein; Provisional; Region: PRK11507
701347010795	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
701347010796	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347010797	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347010798	active site turn [active]
701347010799	phosphorylation site [posttranslational modification]
701347010800	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
701347010801	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347010802	DNA binding site [nucleotide binding]
701347010803	domain linker motif; other site
701347010804	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
701347010805	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
701347010806	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
701347010807	active site
701347010808	HIGH motif; other site
701347010809	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
701347010810	KMSKS motif; other site
701347010811	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
701347010812	tRNA binding surface [nucleotide binding]; other site
701347010813	anticodon binding site; other site
701347010814	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
701347010815	substrate binding site [chemical binding]; other site
701347010816	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
701347010817	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
701347010818	putative active site [active]
701347010819	putative metal binding site [ion binding]; other site
701347010820	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
701347010821	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
701347010822	ATP-grasp domain; Region: ATP-grasp; pfam02222
701347010823	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
701347010824	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
701347010825	active site residue [active]
701347010826	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
701347010827	FtsX-like permease family; Region: FtsX; pfam02687
701347010828	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
701347010829	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
701347010830	Walker A/P-loop; other site
701347010831	ATP binding site [chemical binding]; other site
701347010832	Q-loop/lid; other site
701347010833	ABC transporter signature motif; other site
701347010834	Walker B; other site
701347010835	D-loop; other site
701347010836	H-loop/switch region; other site
701347010837	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
701347010838	active site
701347010839	catalytic triad [active]
701347010840	oxyanion hole [active]
701347010841	switch loop; other site
701347010842	oxidoreductase; Provisional; Region: PRK08017
701347010843	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
701347010844	NADP binding site [chemical binding]; other site
701347010845	active site
701347010846	steroid binding site; other site
701347010847	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
701347010848	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
701347010849	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
701347010850	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
701347010851	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347010852	Walker A/P-loop; other site
701347010853	ATP binding site [chemical binding]; other site
701347010854	Q-loop/lid; other site
701347010855	ABC transporter signature motif; other site
701347010856	Walker B; other site
701347010857	D-loop; other site
701347010858	H-loop/switch region; other site
701347010859	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
701347010860	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
701347010861	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
701347010862	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
701347010863	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
701347010864	DNA binding residues [nucleotide binding]
701347010865	dimer interface [polypeptide binding]; other site
701347010866	copper binding site [ion binding]; other site
701347010867	copper exporting ATPase; Provisional; Region: copA; PRK10671
701347010868	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
701347010869	metal-binding site [ion binding]
701347010870	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
701347010871	metal-binding site [ion binding]
701347010872	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347010873	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347010874	motif II; other site
701347010875	TraB family; Region: TraB; cl12050
701347010876	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
701347010877	putative deacylase active site [active]
701347010878	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
701347010879	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
701347010880	active site
701347010881	metal binding site [ion binding]; metal-binding site
701347010882	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
701347010883	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347010884	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347010885	putative substrate translocation pore; other site
701347010886	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347010887	putative cation:proton antiport protein; Provisional; Region: PRK10669
701347010888	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
701347010889	TrkA-N domain; Region: TrkA_N; pfam02254
701347010890	inosine/guanosine kinase; Provisional; Region: PRK15074
701347010891	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347010892	ferrochelatase; Reviewed; Region: hemH; PRK00035
701347010893	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
701347010894	C-terminal domain interface [polypeptide binding]; other site
701347010895	active site
701347010896	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
701347010897	active site
701347010898	N-terminal domain interface [polypeptide binding]; other site
701347010899	adenylate kinase; Reviewed; Region: adk; PRK00279
701347010900	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
701347010901	AMP-binding site [chemical binding]; other site
701347010902	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
701347010903	heat shock protein 90; Provisional; Region: PRK05218
701347010904	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347010905	ATP binding site [chemical binding]; other site
701347010906	Mg2+ binding site [ion binding]; other site
701347010907	G-X-G motif; other site
701347010908	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
701347010909	RecR protein; Region: RecR; pfam02132
701347010910	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
701347010911	putative active site [active]
701347010912	putative metal-binding site [ion binding]; other site
701347010913	tetramer interface [polypeptide binding]; other site
701347010914	hypothetical protein; Validated; Region: PRK00153
701347010915	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
701347010916	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347010917	Walker A motif; other site
701347010918	ATP binding site [chemical binding]; other site
701347010919	Walker B motif; other site
701347010920	DNA polymerase III subunit delta'; Validated; Region: PRK08485
701347010921	arginine finger; other site
701347010922	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
701347010923	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
701347010924	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
701347010925	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347010926	active site
701347010927	hypothetical protein; Provisional; Region: PRK10527
701347010928	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
701347010929	hypothetical protein; Provisional; Region: PRK11038
701347010930	hypothetical protein; Provisional; Region: PRK11281
701347010931	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
701347010932	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
701347010933	Mechanosensitive ion channel; Region: MS_channel; pfam00924
701347010934	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
701347010935	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347010936	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
701347010937	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
701347010938	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347010939	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347010940	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
701347010941	Protein export membrane protein; Region: SecD_SecF; cl14618
701347010942	Hha toxicity attenuator; Provisional; Region: PRK10667
701347010943	gene expression modulator; Provisional; Region: PRK10945
701347010944	maltose O-acetyltransferase; Provisional; Region: PRK10092
701347010945	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
701347010946	active site
701347010947	substrate binding site [chemical binding]; other site
701347010948	trimer interface [polypeptide binding]; other site
701347010949	CoA binding site [chemical binding]; other site
701347010950	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
701347010951	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
701347010952	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347010953	DNA-binding site [nucleotide binding]; DNA binding site
701347010954	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347010955	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347010956	homodimer interface [polypeptide binding]; other site
701347010957	catalytic residue [active]
701347010958	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
701347010959	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
701347010960	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
701347010961	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
701347010962	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
701347010963	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
701347010964	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347010965	Protein of unknown function (DUF1428); Region: DUF1428; cl02319
701347010966	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
701347010967	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
701347010968	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
701347010969	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
701347010970	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
701347010971	lac repressor; Reviewed; Region: lacI; PRK09526
701347010972	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347010973	DNA binding site [nucleotide binding]
701347010974	domain linker motif; other site
701347010975	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
701347010976	ligand binding site [chemical binding]; other site
701347010977	dimerization interface (open form) [polypeptide binding]; other site
701347010978	dimerization interface (closed form) [polypeptide binding]; other site
701347010979	Predicted membrane protein [Function unknown]; Region: COG2364
701347010980	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
701347010981	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
701347010982	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
701347010983	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347010984	DNA-binding site [nucleotide binding]; DNA binding site
701347010985	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347010986	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347010987	homodimer interface [polypeptide binding]; other site
701347010988	catalytic residue [active]
701347010989	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_3; cd08896
701347010990	putative hydrophobic ligand binding site [chemical binding]; other site
701347010991	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
701347010992	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
701347010993	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
701347010994	putative metal binding site [ion binding]; other site
701347010995	putative homodimer interface [polypeptide binding]; other site
701347010996	putative homotetramer interface [polypeptide binding]; other site
701347010997	putative homodimer-homodimer interface [polypeptide binding]; other site
701347010998	putative allosteric switch controlling residues; other site
701347010999	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
701347011000	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
701347011001	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
701347011002	DNA binding site [nucleotide binding]
701347011003	active site
701347011004	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
701347011005	acyl-CoA thioesterase II; Provisional; Region: PRK10526
701347011006	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
701347011007	active site
701347011008	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
701347011009	catalytic triad [active]
701347011010	dimer interface [polypeptide binding]; other site
701347011011	ammonium transporter; Provisional; Region: PRK10666
701347011012	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
701347011013	Nitrogen regulatory protein P-II; Region: P-II; smart00938
701347011014	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
701347011015	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
701347011016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347011017	Walker A/P-loop; other site
701347011018	ATP binding site [chemical binding]; other site
701347011019	Q-loop/lid; other site
701347011020	ABC transporter signature motif; other site
701347011021	Walker B; other site
701347011022	D-loop; other site
701347011023	H-loop/switch region; other site
701347011024	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
701347011025	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
701347011026	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347011027	Walker A/P-loop; other site
701347011028	ATP binding site [chemical binding]; other site
701347011029	Q-loop/lid; other site
701347011030	ABC transporter signature motif; other site
701347011031	Walker B; other site
701347011032	D-loop; other site
701347011033	H-loop/switch region; other site
701347011034	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
701347011035	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347011036	putative DNA binding site [nucleotide binding]; other site
701347011037	putative Zn2+ binding site [ion binding]; other site
701347011038	AsnC family; Region: AsnC_trans_reg; pfam01037
701347011039	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
701347011040	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
701347011041	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
701347011042	catalytic residue [active]
701347011043	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
701347011044	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347011045	active site
701347011046	motif I; other site
701347011047	motif II; other site
701347011048	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
701347011049	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
701347011050	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
701347011051	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
701347011052	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
701347011053	Ligand Binding Site [chemical binding]; other site
701347011054	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
701347011055	active site
701347011056	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
701347011057	periplasmic folding chaperone; Provisional; Region: PRK10788
701347011058	SurA N-terminal domain; Region: SurA_N_3; cl07813
701347011059	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
701347011060	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
701347011061	IHF dimer interface [polypeptide binding]; other site
701347011062	IHF - DNA interface [nucleotide binding]; other site
701347011063	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
701347011064	Found in ATP-dependent protease La (LON); Region: LON; smart00464
701347011065	Found in ATP-dependent protease La (LON); Region: LON; smart00464
701347011066	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347011067	Walker A motif; other site
701347011068	ATP binding site [chemical binding]; other site
701347011069	Walker B motif; other site
701347011070	arginine finger; other site
701347011071	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
701347011072	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
701347011073	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
701347011074	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347011075	Walker A motif; other site
701347011076	ATP binding site [chemical binding]; other site
701347011077	Walker B motif; other site
701347011078	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
701347011079	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
701347011080	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
701347011081	oligomer interface [polypeptide binding]; other site
701347011082	active site residues [active]
701347011083	trigger factor; Provisional; Region: tig; PRK01490
701347011084	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
701347011085	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
701347011086	transcriptional regulator BolA; Provisional; Region: PRK11628
701347011087	hypothetical protein; Provisional; Region: PRK11627
701347011088	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
701347011089	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
701347011090	muropeptide transporter; Reviewed; Region: ampG; PRK11902
701347011091	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347011092	putative substrate translocation pore; other site
701347011093	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
701347011094	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
701347011095	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
701347011096	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
701347011097	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
701347011098	D-pathway; other site
701347011099	Putative ubiquinol binding site [chemical binding]; other site
701347011100	Low-spin heme (heme b) binding site [chemical binding]; other site
701347011101	Putative water exit pathway; other site
701347011102	Binuclear center (heme o3/CuB) [ion binding]; other site
701347011103	K-pathway; other site
701347011104	Putative proton exit pathway; other site
701347011105	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
701347011106	Subunit I/III interface [polypeptide binding]; other site
701347011107	Subunit III/IV interface [polypeptide binding]; other site
701347011108	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
701347011109	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
701347011110	UbiA prenyltransferase family; Region: UbiA; pfam01040
701347011111	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347011112	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347011113	putative substrate translocation pore; other site
701347011114	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
701347011115	L-fuculokinase; Provisional; Region: PRK10331
701347011116	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
701347011117	nucleotide binding site [chemical binding]; other site
701347011118	L-fucose isomerase; Provisional; Region: fucI; PRK10991
701347011119	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
701347011120	hexamer (dimer of trimers) interface [polypeptide binding]; other site
701347011121	trimer interface [polypeptide binding]; other site
701347011122	substrate binding site [chemical binding]; other site
701347011123	Mn binding site [ion binding]; other site
701347011124	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347011125	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347011126	Walker A/P-loop; other site
701347011127	ATP binding site [chemical binding]; other site
701347011128	Q-loop/lid; other site
701347011129	ABC transporter signature motif; other site
701347011130	Walker B; other site
701347011131	D-loop; other site
701347011132	H-loop/switch region; other site
701347011133	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347011134	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347011135	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347011136	TM-ABC transporter signature motif; other site
701347011137	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310
701347011138	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
701347011139	putative ligand binding site [chemical binding]; other site
701347011140	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347011141	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347011142	DNA binding site [nucleotide binding]
701347011143	domain linker motif; other site
701347011144	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
701347011145	dimerization interface [polypeptide binding]; other site
701347011146	ligand binding site [chemical binding]; other site
701347011147	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
701347011148	intersubunit interface [polypeptide binding]; other site
701347011149	active site
701347011150	Zn2+ binding site [ion binding]; other site
701347011151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
701347011152	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
701347011153	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
701347011154	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
701347011155	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
701347011156	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
701347011157	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
701347011158	conserved cys residue [active]
701347011159	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
701347011160	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
701347011161	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
701347011162	Ligand Binding Site [chemical binding]; other site
701347011163	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
701347011164	active site residue [active]
701347011165	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
701347011166	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
701347011167	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
701347011168	substrate binding pocket [chemical binding]; other site
701347011169	chain length determination region; other site
701347011170	substrate-Mg2+ binding site; other site
701347011171	catalytic residues [active]
701347011172	aspartate-rich region 1; other site
701347011173	active site lid residues [active]
701347011174	aspartate-rich region 2; other site
701347011175	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
701347011176	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
701347011177	TPP-binding site; other site
701347011178	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
701347011179	PYR/PP interface [polypeptide binding]; other site
701347011180	dimer interface [polypeptide binding]; other site
701347011181	TPP binding site [chemical binding]; other site
701347011182	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
701347011183	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
701347011184	tetramer interfaces [polypeptide binding]; other site
701347011185	binuclear metal-binding site [ion binding]; other site
701347011186	thiamine monophosphate kinase; Provisional; Region: PRK05731
701347011187	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
701347011188	ATP binding site [chemical binding]; other site
701347011189	dimerization interface [polypeptide binding]; other site
701347011190	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
701347011191	putative RNA binding site [nucleotide binding]; other site
701347011192	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
701347011193	homopentamer interface [polypeptide binding]; other site
701347011194	active site
701347011195	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
701347011196	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
701347011197	catalytic motif [active]
701347011198	Zn binding site [ion binding]; other site
701347011199	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
701347011200	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
701347011201	ATP cone domain; Region: ATP-cone; pfam03477
701347011202	hypothetical protein; Provisional; Region: PRK11530
701347011203	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
701347011204	Predicted transcriptional regulator [Transcription]; Region: COG2378
701347011205	HTH domain; Region: HTH_11; pfam08279
701347011206	WYL domain; Region: WYL; pfam13280
701347011207	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
701347011208	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
701347011209	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
701347011210	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
701347011211	active site
701347011212	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
701347011213	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
701347011214	Protein export membrane protein; Region: SecD_SecF; pfam02355
701347011215	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
701347011216	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
701347011217	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
701347011218	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
701347011219	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
701347011220	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
701347011221	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
701347011222	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
701347011223	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
701347011224	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
701347011225	peroxidase; Provisional; Region: PRK15000
701347011226	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
701347011227	dimer interface [polypeptide binding]; other site
701347011228	decamer (pentamer of dimers) interface [polypeptide binding]; other site
701347011229	catalytic triad [active]
701347011230	peroxidatic and resolving cysteines [active]
701347011231	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
701347011232	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
701347011233	active site
701347011234	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
701347011235	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
701347011236	Isochorismatase family; Region: Isochorismatase; pfam00857
701347011237	catalytic triad [active]
701347011238	dimer interface [polypeptide binding]; other site
701347011239	conserved cis-peptide bond; other site
701347011240	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347011241	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347011242	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347011243	dimerization interface [polypeptide binding]; other site
701347011244	maltodextrin glucosidase; Provisional; Region: PRK10785
701347011245	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
701347011246	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
701347011247	active site
701347011248	homodimer interface [polypeptide binding]; other site
701347011249	catalytic site [active]
701347011250	putative proline-specific permease; Provisional; Region: proY; PRK10580
701347011251	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
701347011252	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
701347011253	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
701347011254	PAS domain; Region: PAS; smart00091
701347011255	putative active site [active]
701347011256	heme pocket [chemical binding]; other site
701347011257	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347011258	dimer interface [polypeptide binding]; other site
701347011259	phosphorylation site [posttranslational modification]
701347011260	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347011261	ATP binding site [chemical binding]; other site
701347011262	Mg2+ binding site [ion binding]; other site
701347011263	G-X-G motif; other site
701347011264	transcriptional regulator PhoB; Provisional; Region: PRK10161
701347011265	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347011266	active site
701347011267	phosphorylation site [posttranslational modification]
701347011268	intermolecular recognition site; other site
701347011269	dimerization interface [polypeptide binding]; other site
701347011270	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347011271	DNA binding site [nucleotide binding]
701347011272	exonuclease subunit SbcD; Provisional; Region: PRK10966
701347011273	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
701347011274	active site
701347011275	metal binding site [ion binding]; metal-binding site
701347011276	DNA binding site [nucleotide binding]
701347011277	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
701347011278	exonuclease subunit SbcC; Provisional; Region: PRK10246
701347011279	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347011280	Walker A/P-loop; other site
701347011281	ATP binding site [chemical binding]; other site
701347011282	Q-loop/lid; other site
701347011283	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347011284	ABC transporter signature motif; other site
701347011285	Walker B; other site
701347011286	D-loop; other site
701347011287	H-loop/switch region; other site
701347011288	fructokinase; Reviewed; Region: PRK09557
701347011289	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347011290	nucleotide binding site [chemical binding]; other site
701347011291	recombination associated protein; Reviewed; Region: rdgC; PRK00321
701347011292	hypothetical protein; Provisional; Region: PRK10579
701347011293	hypothetical protein; Provisional; Region: PRK10481
701347011294	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
701347011295	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
701347011296	ADP binding site [chemical binding]; other site
701347011297	magnesium binding site [ion binding]; other site
701347011298	putative shikimate binding site; other site
701347011299	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
701347011300	hypothetical protein; Validated; Region: PRK00124
701347011301	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
701347011302	pyrroline-5-carboxylate reductase; Region: PLN02688
701347011303	psiF repeat; Region: PsiF_repeat; pfam07769
701347011304	psiF repeat; Region: PsiF_repeat; pfam07769
701347011305	drug efflux system protein MdtG; Provisional; Region: PRK09874
701347011306	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347011307	putative substrate translocation pore; other site
701347011308	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
701347011309	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
701347011310	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
701347011311	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
701347011312	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
701347011313	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
701347011314	microcin B17 transporter; Reviewed; Region: PRK11098
701347011315	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
701347011316	catalytic triad [active]
701347011317	conserved cis-peptide bond; other site
701347011318	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
701347011319	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
701347011320	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
701347011321	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
701347011322	dimer interface [polypeptide binding]; other site
701347011323	active site
701347011324	Schiff base residues; other site
701347011325	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
701347011326	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
701347011327	putative acyl-acceptor binding pocket; other site
701347011328	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
701347011329	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
701347011330	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
701347011331	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
701347011332	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
701347011333	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347011334	dimer interface [polypeptide binding]; other site
701347011335	conserved gate region; other site
701347011336	putative PBP binding loops; other site
701347011337	ABC-ATPase subunit interface; other site
701347011338	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
701347011339	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
701347011340	Walker A/P-loop; other site
701347011341	ATP binding site [chemical binding]; other site
701347011342	Q-loop/lid; other site
701347011343	ABC transporter signature motif; other site
701347011344	Walker B; other site
701347011345	D-loop; other site
701347011346	H-loop/switch region; other site
701347011347	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
701347011348	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347011349	substrate binding pocket [chemical binding]; other site
701347011350	membrane-bound complex binding site; other site
701347011351	hinge residues; other site
701347011352	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
701347011353	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
701347011354	Autotransporter beta-domain; Region: Autotransporter; pfam03797
701347011355	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
701347011356	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
701347011357	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347011358	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347011359	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
701347011360	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347011361	substrate binding pocket [chemical binding]; other site
701347011362	membrane-bound complex binding site; other site
701347011363	hinge residues; other site
701347011364	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
701347011365	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
701347011366	Walker A/P-loop; other site
701347011367	ATP binding site [chemical binding]; other site
701347011368	Q-loop/lid; other site
701347011369	ABC transporter signature motif; other site
701347011370	Walker B; other site
701347011371	D-loop; other site
701347011372	H-loop/switch region; other site
701347011373	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347011374	dimer interface [polypeptide binding]; other site
701347011375	conserved gate region; other site
701347011376	putative PBP binding loops; other site
701347011377	ABC-ATPase subunit interface; other site
701347011378	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347011379	dimer interface [polypeptide binding]; other site
701347011380	conserved gate region; other site
701347011381	putative PBP binding loops; other site
701347011382	ABC-ATPase subunit interface; other site
701347011383	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347011384	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347011385	metal binding site [ion binding]; metal-binding site
701347011386	active site
701347011387	I-site; other site
701347011388	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
701347011389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
701347011390	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347011391	dimerization domain swap beta strand [polypeptide binding]; other site
701347011392	regulatory protein interface [polypeptide binding]; other site
701347011393	active site
701347011394	regulatory phosphorylation site [posttranslational modification]; other site
701347011395	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
701347011396	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
701347011397	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
701347011398	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
701347011399	Dak1 domain; Region: Dak1; pfam02733
701347011400	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
701347011401	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
701347011402	dimer interface [polypeptide binding]; other site
701347011403	active site
701347011404	metal binding site [ion binding]; metal-binding site
701347011405	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
701347011406	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347011407	putative active site [active]
701347011408	heme pocket [chemical binding]; other site
701347011409	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347011410	Walker A motif; other site
701347011411	ATP binding site [chemical binding]; other site
701347011412	Walker B motif; other site
701347011413	arginine finger; other site
701347011414	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347011415	dimerization interface [polypeptide binding]; other site
701347011416	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
701347011417	DNA binding residues [nucleotide binding]
701347011418	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
701347011419	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
701347011420	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
701347011421	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
701347011422	ligand binding site [chemical binding]; other site
701347011423	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
701347011424	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
701347011425	trimer interface [polypeptide binding]; other site
701347011426	Haemagglutinin; Region: HIM; pfam05662
701347011427	YadA-like C-terminal region; Region: YadA; pfam03895
701347011428	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
701347011429	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
701347011430	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
701347011431	active site 1 [active]
701347011432	dimer interface [polypeptide binding]; other site
701347011433	hexamer interface [polypeptide binding]; other site
701347011434	active site 2 [active]
701347011435	LysR family transcriptional regulator; Provisional; Region: PRK14997
701347011436	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347011437	dimerization interface [polypeptide binding]; other site
701347011438	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
701347011439	tetramer interface [polypeptide binding]; other site
701347011440	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
701347011441	active site
701347011442	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
701347011443	classical (c) SDRs; Region: SDR_c; cd05233
701347011444	NAD(P) binding site [chemical binding]; other site
701347011445	active site
701347011446	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
701347011447	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
701347011448	substrate binding site [chemical binding]; other site
701347011449	hexamer interface [polypeptide binding]; other site
701347011450	metal binding site [ion binding]; metal-binding site
701347011451	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
701347011452	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
701347011453	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
701347011454	active site
701347011455	P-loop; other site
701347011456	phosphorylation site [posttranslational modification]
701347011457	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347011458	active site
701347011459	phosphorylation site [posttranslational modification]
701347011460	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
701347011461	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
701347011462	Protein of unknown function (DUF1302); Region: DUF1302; pfam06980
701347011463	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
701347011464	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
701347011465	putative catalytic cysteine [active]
701347011466	gamma-glutamyl kinase; Provisional; Region: PRK05429
701347011467	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
701347011468	nucleotide binding site [chemical binding]; other site
701347011469	homotetrameric interface [polypeptide binding]; other site
701347011470	putative phosphate binding site [ion binding]; other site
701347011471	putative allosteric binding site; other site
701347011472	PUA domain; Region: PUA; pfam01472
701347011473	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
701347011474	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
701347011475	trimer interface [polypeptide binding]; other site
701347011476	eyelet of channel; other site
701347011477	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
701347011478	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
701347011479	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347011480	active site
701347011481	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
701347011482	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
701347011483	metal binding site [ion binding]; metal-binding site
701347011484	dimer interface [polypeptide binding]; other site
701347011485	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
701347011486	active site
701347011487	DNA polymerase IV; Validated; Region: PRK02406
701347011488	DNA binding site [nucleotide binding]
701347011489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991
701347011490	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
701347011491	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
701347011492	FAD binding pocket [chemical binding]; other site
701347011493	FAD binding motif [chemical binding]; other site
701347011494	phosphate binding motif [ion binding]; other site
701347011495	beta-alpha-beta structure motif; other site
701347011496	NAD binding pocket [chemical binding]; other site
701347011497	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
701347011498	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
701347011499	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
701347011500	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
701347011501	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
701347011502	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
701347011503	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
701347011504	E3 interaction surface; other site
701347011505	lipoyl attachment site [posttranslational modification]; other site
701347011506	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
701347011507	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
701347011508	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
701347011509	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
701347011510	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
701347011511	putative active site [active]
701347011512	putative dimer interface [polypeptide binding]; other site
701347011513	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
701347011514	dimer interface [polypeptide binding]; other site
701347011515	active site
701347011516	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
701347011517	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
701347011518	active site
701347011519	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
701347011520	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
701347011521	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
701347011522	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
701347011523	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
701347011524	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347011525	putative active site [active]
701347011526	heme pocket [chemical binding]; other site
701347011527	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347011528	Walker A motif; other site
701347011529	ATP binding site [chemical binding]; other site
701347011530	Walker B motif; other site
701347011531	arginine finger; other site
701347011532	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347011533	glyoxylate carboligase; Provisional; Region: PRK11269
701347011534	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
701347011535	PYR/PP interface [polypeptide binding]; other site
701347011536	dimer interface [polypeptide binding]; other site
701347011537	TPP binding site [chemical binding]; other site
701347011538	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347011539	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
701347011540	TPP-binding site [chemical binding]; other site
701347011541	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
701347011542	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
701347011543	Metal-binding active site; metal-binding site
701347011544	tartronate semialdehyde reductase; Provisional; Region: PRK15059
701347011545	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
701347011546	glycerate kinase; Region: TIGR00045
701347011547	BCCT family transporter; Region: BCCT; pfam02028
701347011548	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
701347011549	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347011550	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347011551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347011552	putative substrate translocation pore; other site
701347011553	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
701347011554	Dak1 domain; Region: Dak1; pfam02733
701347011555	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
701347011556	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
701347011557	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
701347011558	active pocket/dimerization site; other site
701347011559	active site
701347011560	phosphorylation site [posttranslational modification]
701347011561	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347011562	dimerization domain swap beta strand [polypeptide binding]; other site
701347011563	regulatory protein interface [polypeptide binding]; other site
701347011564	active site
701347011565	regulatory phosphorylation site [posttranslational modification]; other site
701347011566	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
701347011567	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
701347011568	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
701347011569	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
701347011570	C-N hydrolase family amidase; Provisional; Region: PRK10438
701347011571	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
701347011572	putative active site [active]
701347011573	catalytic triad [active]
701347011574	dimer interface [polypeptide binding]; other site
701347011575	multimer interface [polypeptide binding]; other site
701347011576	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
701347011577	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
701347011578	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
701347011579	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
701347011580	HlyD family secretion protein; Region: HlyD_3; pfam13437
701347011581	voltage-gated potassium channel; Provisional; Region: PRK10537
701347011582	Major Facilitator Superfamily; Region: MFS_1; pfam07690
701347011583	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347011584	xanthine permease; Region: pbuX; TIGR03173
701347011585	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
701347011586	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
701347011587	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
701347011588	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
701347011589	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
701347011590	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
701347011591	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
701347011592	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
701347011593	lysine decarboxylase CadA; Provisional; Region: PRK15400
701347011594	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
701347011595	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
701347011596	homodimer interface [polypeptide binding]; other site
701347011597	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347011598	catalytic residue [active]
701347011599	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
701347011600	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
701347011601	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
701347011602	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347011603	DNA binding site [nucleotide binding]
701347011604	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
701347011605	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
701347011606	dimer interface [polypeptide binding]; other site
701347011607	putative anticodon binding site; other site
701347011608	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
701347011609	motif 1; other site
701347011610	active site
701347011611	motif 2; other site
701347011612	motif 3; other site
701347011613	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
701347011614	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
701347011615	active site
701347011616	catalytic site [active]
701347011617	substrate binding site [chemical binding]; other site
701347011618	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
701347011619	RNA/DNA hybrid binding site [nucleotide binding]; other site
701347011620	active site
701347011621	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347011622	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
701347011623	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
701347011624	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347011625	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347011626	catalytic residue [active]
701347011627	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347011628	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
701347011629	Methyltransferase domain; Region: Methyltransf_31; pfam13847
701347011630	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347011631	S-adenosylmethionine binding site [chemical binding]; other site
701347011632	hypothetical protein; Provisional; Region: PRK05421
701347011633	putative catalytic site [active]
701347011634	putative metal binding site [ion binding]; other site
701347011635	putative phosphate binding site [ion binding]; other site
701347011636	putative catalytic site [active]
701347011637	putative phosphate binding site [ion binding]; other site
701347011638	putative metal binding site [ion binding]; other site
701347011639	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
701347011640	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347011641	putative substrate translocation pore; other site
701347011642	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347011643	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347011644	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
701347011645	putative effector binding pocket; other site
701347011646	dimerization interface [polypeptide binding]; other site
701347011647	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
701347011648	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
701347011649	active site
701347011650	catalytic tetrad [active]
701347011651	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
701347011652	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347011653	active site
701347011654	motif I; other site
701347011655	motif II; other site
701347011656	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
701347011657	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
701347011658	Walker A/P-loop; other site
701347011659	ATP binding site [chemical binding]; other site
701347011660	Q-loop/lid; other site
701347011661	ABC transporter signature motif; other site
701347011662	Walker B; other site
701347011663	D-loop; other site
701347011664	H-loop/switch region; other site
701347011665	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
701347011666	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347011667	dimer interface [polypeptide binding]; other site
701347011668	conserved gate region; other site
701347011669	ABC-ATPase subunit interface; other site
701347011670	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
701347011671	lipoprotein, YaeC family; Region: TIGR00363
701347011672	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
701347011673	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
701347011674	homodimer interaction site [polypeptide binding]; other site
701347011675	cofactor binding site; other site
701347011676	prolyl-tRNA synthetase; Provisional; Region: PRK09194
701347011677	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
701347011678	dimer interface [polypeptide binding]; other site
701347011679	motif 1; other site
701347011680	active site
701347011681	motif 2; other site
701347011682	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
701347011683	putative deacylase active site [active]
701347011684	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
701347011685	active site
701347011686	motif 3; other site
701347011687	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
701347011688	anticodon binding site; other site
701347011689	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
701347011690	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
701347011691	NlpE N-terminal domain; Region: NlpE; pfam04170
701347011692	hypothetical protein; Provisional; Region: PRK09256
701347011693	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
701347011694	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
701347011695	hypothetical protein; Provisional; Region: PRK04964
701347011696	Rho-binding antiterminator; Provisional; Region: PRK11625
701347011697	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
701347011698	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
701347011699	Ligand Binding Site [chemical binding]; other site
701347011700	TilS substrate binding domain; Region: TilS; pfam09179
701347011701	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
701347011702	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
701347011703	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
701347011704	putative metal binding site [ion binding]; other site
701347011705	lysine decarboxylase LdcC; Provisional; Region: PRK15399
701347011706	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
701347011707	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
701347011708	homodimer interface [polypeptide binding]; other site
701347011709	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347011710	catalytic residue [active]
701347011711	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
701347011712	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
701347011713	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
701347011714	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
701347011715	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
701347011716	putative active site [active]
701347011717	putative PHP Thumb interface [polypeptide binding]; other site
701347011718	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
701347011719	generic binding surface II; other site
701347011720	generic binding surface I; other site
701347011721	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
701347011722	RNA/DNA hybrid binding site [nucleotide binding]; other site
701347011723	active site
701347011724	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
701347011725	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
701347011726	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
701347011727	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
701347011728	active site
701347011729	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
701347011730	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
701347011731	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
701347011732	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
701347011733	trimer interface [polypeptide binding]; other site
701347011734	active site
701347011735	UDP-GlcNAc binding site [chemical binding]; other site
701347011736	lipid binding site [chemical binding]; lipid-binding site
701347011737	periplasmic chaperone; Provisional; Region: PRK10780
701347011738	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
701347011739	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
701347011740	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
701347011741	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
701347011742	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
701347011743	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
701347011744	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
701347011745	Surface antigen; Region: Bac_surface_Ag; pfam01103
701347011746	zinc metallopeptidase RseP; Provisional; Region: PRK10779
701347011747	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
701347011748	active site
701347011749	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
701347011750	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
701347011751	protein binding site [polypeptide binding]; other site
701347011752	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
701347011753	putative substrate binding region [chemical binding]; other site
701347011754	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
701347011755	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
701347011756	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
701347011757	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
701347011758	catalytic residue [active]
701347011759	putative FPP diphosphate  binding site; other site
701347011760	putative FPP binding hydrophobic cleft; other site
701347011761	dimer interface [polypeptide binding]; other site
701347011762	putative IPP diphosphate binding site; other site
701347011763	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
701347011764	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
701347011765	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
701347011766	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
701347011767	ribosome recycling factor; Reviewed; Region: frr; PRK00083
701347011768	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
701347011769	hinge region; other site
701347011770	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
701347011771	putative nucleotide binding site [chemical binding]; other site
701347011772	uridine monophosphate binding site [chemical binding]; other site
701347011773	homohexameric interface [polypeptide binding]; other site
701347011774	elongation factor Ts; Provisional; Region: tsf; PRK09377
701347011775	UBA/TS-N domain; Region: UBA; pfam00627
701347011776	Elongation factor TS; Region: EF_TS; pfam00889
701347011777	Elongation factor TS; Region: EF_TS; pfam00889
701347011778	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
701347011779	rRNA interaction site [nucleotide binding]; other site
701347011780	S8 interaction site; other site
701347011781	putative laminin-1 binding site; other site
701347011782	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
701347011783	active site
701347011784	PII uridylyl-transferase; Provisional; Region: PRK05007
701347011785	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
701347011786	metal binding triad; other site
701347011787	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
701347011788	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
701347011789	Zn2+ binding site [ion binding]; other site
701347011790	Mg2+ binding site [ion binding]; other site
701347011791	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
701347011792	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
701347011793	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
701347011794	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
701347011795	trimer interface [polypeptide binding]; other site
701347011796	active site
701347011797	substrate binding site [chemical binding]; other site
701347011798	CoA binding site [chemical binding]; other site
701347011799	hypothetical protein; Provisional; Region: PRK13677
701347011800	serine endoprotease; Provisional; Region: PRK10942
701347011801	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
701347011802	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
701347011803	protein binding site [polypeptide binding]; other site
701347011804	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
701347011805	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
701347011806	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
701347011807	Zn2+ binding site [ion binding]; other site
701347011808	Mg2+ binding site [ion binding]; other site
701347011809	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
701347011810	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
701347011811	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
701347011812	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
701347011813	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
701347011814	cobalamin binding residues [chemical binding]; other site
701347011815	putative BtuC binding residues; other site
701347011816	dimer interface [polypeptide binding]; other site
701347011817	hypothetical protein; Provisional; Region: PRK10578
701347011818	UPF0126 domain; Region: UPF0126; pfam03458
701347011819	UPF0126 domain; Region: UPF0126; pfam03458
701347011820	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
701347011821	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
701347011822	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
701347011823	Cl- selectivity filter; other site
701347011824	Cl- binding residues [ion binding]; other site
701347011825	pore gating glutamate residue; other site
701347011826	dimer interface [polypeptide binding]; other site
701347011827	H+/Cl- coupling transport residue; other site
701347011828	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
701347011829	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
701347011830	inhibitor-cofactor binding pocket; inhibition site
701347011831	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347011832	catalytic residue [active]
701347011833	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
701347011834	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347011835	ABC-ATPase subunit  interface; other site
701347011836	dimer interface [polypeptide binding]; other site
701347011837	putative PBP binding regions; other site
701347011838	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347011839	ABC-ATPase subunit  interface; other site
701347011840	dimer interface [polypeptide binding]; other site
701347011841	putative PBP binding regions; other site
701347011842	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
701347011843	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
701347011844	siderophore binding site; other site
701347011845	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
701347011846	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
701347011847	Walker A/P-loop; other site
701347011848	ATP binding site [chemical binding]; other site
701347011849	Q-loop/lid; other site
701347011850	ABC transporter signature motif; other site
701347011851	Walker B; other site
701347011852	D-loop; other site
701347011853	H-loop/switch region; other site
701347011854	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
701347011855	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347011856	N-terminal plug; other site
701347011857	ligand-binding site [chemical binding]; other site
701347011858	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
701347011859	Transglycosylase; Region: Transgly; pfam00912
701347011860	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
701347011861	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
701347011862	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347011863	ATP binding site [chemical binding]; other site
701347011864	putative Mg++ binding site [ion binding]; other site
701347011865	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347011866	nucleotide binding region [chemical binding]; other site
701347011867	ATP-binding site [chemical binding]; other site
701347011868	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
701347011869	2'-5' RNA ligase; Provisional; Region: PRK15124
701347011870	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
701347011871	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
701347011872	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
701347011873	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
701347011874	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
701347011875	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
701347011876	active site
701347011877	HIGH motif; other site
701347011878	nucleotide binding site [chemical binding]; other site
701347011879	KMSKS motif; other site
701347011880	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
701347011881	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
701347011882	active site
701347011883	NTP binding site [chemical binding]; other site
701347011884	metal binding triad [ion binding]; metal-binding site
701347011885	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
701347011886	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
701347011887	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
701347011888	catalytic center binding site [active]
701347011889	ATP binding site [chemical binding]; other site
701347011890	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
701347011891	oligomerization interface [polypeptide binding]; other site
701347011892	active site
701347011893	metal binding site [ion binding]; metal-binding site
701347011894	pantoate--beta-alanine ligase; Region: panC; TIGR00018
701347011895	Pantoate-beta-alanine ligase; Region: PanC; cd00560
701347011896	active site
701347011897	ATP-binding site [chemical binding]; other site
701347011898	pantoate-binding site; other site
701347011899	HXXH motif; other site
701347011900	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
701347011901	tetramerization interface [polypeptide binding]; other site
701347011902	active site
701347011903	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
701347011904	putative active site [active]
701347011905	putative metal binding site [ion binding]; other site
701347011906	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
701347011907	active pocket/dimerization site; other site
701347011908	active site
701347011909	phosphorylation site [posttranslational modification]
701347011910	inner membrane transport permease; Provisional; Region: PRK15066
701347011911	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
701347011912	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
701347011913	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
701347011914	Walker A/P-loop; other site
701347011915	ATP binding site [chemical binding]; other site
701347011916	Q-loop/lid; other site
701347011917	ABC transporter signature motif; other site
701347011918	Walker B; other site
701347011919	D-loop; other site
701347011920	H-loop/switch region; other site
701347011921	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
701347011922	active site clefts [active]
701347011923	zinc binding site [ion binding]; other site
701347011924	dimer interface [polypeptide binding]; other site
701347011925	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
701347011926	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
701347011927	active site
701347011928	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
701347011929	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
701347011930	Trp docking motif [polypeptide binding]; other site
701347011931	putative active site [active]
701347011932	multicopper oxidase; Provisional; Region: PRK10965
701347011933	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
701347011934	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
701347011935	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
701347011936	spermidine synthase; Provisional; Region: PRK00811
701347011937	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347011938	S-adenosylmethionine binding site [chemical binding]; other site
701347011939	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
701347011940	hypothetical protein; Provisional; Region: PRK05248
701347011941	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
701347011942	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
701347011943	substrate binding site [chemical binding]; other site
701347011944	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
701347011945	substrate binding site [chemical binding]; other site
701347011946	ligand binding site [chemical binding]; other site
701347011947	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
701347011948	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
701347011949	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
701347011950	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
701347011951	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347011952	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
701347011953	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
701347011954	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
701347011955	E3 interaction surface; other site
701347011956	lipoyl attachment site [posttranslational modification]; other site
701347011957	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
701347011958	E3 interaction surface; other site
701347011959	lipoyl attachment site [posttranslational modification]; other site
701347011960	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
701347011961	E3 interaction surface; other site
701347011962	lipoyl attachment site [posttranslational modification]; other site
701347011963	e3 binding domain; Region: E3_binding; pfam02817
701347011964	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
701347011965	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
701347011966	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
701347011967	dimer interface [polypeptide binding]; other site
701347011968	TPP-binding site [chemical binding]; other site
701347011969	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
701347011970	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347011971	DNA-binding site [nucleotide binding]; DNA binding site
701347011972	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
701347011973	aromatic amino acid transporter; Provisional; Region: PRK10238
701347011974	regulatory protein AmpE; Provisional; Region: PRK10987
701347011975	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
701347011976	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
701347011977	amidase catalytic site [active]
701347011978	substrate binding site [chemical binding]; other site
701347011979	Zn binding residues [ion binding]; other site
701347011980	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
701347011981	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
701347011982	dimerization interface [polypeptide binding]; other site
701347011983	active site
701347011984	putative major pilin subunit; Provisional; Region: PRK10574
701347011985	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
701347011986	hypothetical protein; Provisional; Region: PRK10436
701347011987	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
701347011988	Walker A motif; other site
701347011989	ATP binding site [chemical binding]; other site
701347011990	Walker B motif; other site
701347011991	type IV pilin biogenesis protein; Provisional; Region: PRK10573
701347011992	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
701347011993	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
701347011994	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
701347011995	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
701347011996	active site
701347011997	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
701347011998	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
701347011999	CoA-binding site [chemical binding]; other site
701347012000	ATP-binding [chemical binding]; other site
701347012001	hypothetical protein; Provisional; Region: PRK05287
701347012002	DNA gyrase inhibitor; Reviewed; Region: PRK00418
701347012003	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
701347012004	active site
701347012005	8-oxo-dGMP binding site [chemical binding]; other site
701347012006	nudix motif; other site
701347012007	metal binding site [ion binding]; metal-binding site
701347012008	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
701347012009	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
701347012010	SEC-C motif; Region: SEC-C; pfam02810
701347012011	SecA regulator SecM; Provisional; Region: PRK02943
701347012012	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
701347012013	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
701347012014	cell division protein FtsZ; Validated; Region: PRK09330
701347012015	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
701347012016	nucleotide binding site [chemical binding]; other site
701347012017	SulA interaction site; other site
701347012018	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
701347012019	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
701347012020	Cell division protein FtsA; Region: FtsA; pfam14450
701347012021	cell division protein FtsQ; Provisional; Region: PRK10775
701347012022	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
701347012023	Cell division protein FtsQ; Region: FtsQ; pfam03799
701347012024	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
701347012025	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
701347012026	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
701347012027	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
701347012028	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
701347012029	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
701347012030	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
701347012031	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
701347012032	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
701347012033	active site
701347012034	homodimer interface [polypeptide binding]; other site
701347012035	cell division protein FtsW; Provisional; Region: PRK10774
701347012036	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
701347012037	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
701347012038	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
701347012039	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
701347012040	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
701347012041	Mg++ binding site [ion binding]; other site
701347012042	putative catalytic motif [active]
701347012043	putative substrate binding site [chemical binding]; other site
701347012044	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
701347012045	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
701347012046	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
701347012047	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
701347012048	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
701347012049	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
701347012050	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
701347012051	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
701347012052	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
701347012053	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
701347012054	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
701347012055	cell division protein FtsL; Provisional; Region: PRK10772
701347012056	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
701347012057	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
701347012058	mraZ protein; Region: TIGR00242
701347012059	MraZ protein; Region: MraZ; pfam02381
701347012060	MraZ protein; Region: MraZ; pfam02381
701347012061	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
701347012062	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347012063	DNA binding site [nucleotide binding]
701347012064	domain linker motif; other site
701347012065	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
701347012066	dimerization interface [polypeptide binding]; other site
701347012067	ligand binding site [chemical binding]; other site
701347012068	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
701347012069	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
701347012070	putative valine binding site [chemical binding]; other site
701347012071	dimer interface [polypeptide binding]; other site
701347012072	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
701347012073	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
701347012074	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
701347012075	PYR/PP interface [polypeptide binding]; other site
701347012076	dimer interface [polypeptide binding]; other site
701347012077	TPP binding site [chemical binding]; other site
701347012078	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347012079	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
701347012080	TPP-binding site [chemical binding]; other site
701347012081	dimer interface [polypeptide binding]; other site
701347012082	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
701347012083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347012084	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
701347012085	putative substrate binding pocket [chemical binding]; other site
701347012086	putative dimerization interface [polypeptide binding]; other site
701347012087	2-isopropylmalate synthase; Validated; Region: PRK00915
701347012088	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
701347012089	active site
701347012090	catalytic residues [active]
701347012091	metal binding site [ion binding]; metal-binding site
701347012092	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
701347012093	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
701347012094	tartrate dehydrogenase; Provisional; Region: PRK08194
701347012095	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
701347012096	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
701347012097	substrate binding site [chemical binding]; other site
701347012098	ligand binding site [chemical binding]; other site
701347012099	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
701347012100	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
701347012101	substrate binding site [chemical binding]; other site
701347012102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347012103	sugar efflux transporter; Region: 2A0120; TIGR00899
701347012104	putative substrate translocation pore; other site
701347012105	transcriptional regulator SgrR; Provisional; Region: PRK13626
701347012106	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
701347012107	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
701347012108	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
701347012109	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
701347012110	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
701347012111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347012112	dimer interface [polypeptide binding]; other site
701347012113	conserved gate region; other site
701347012114	putative PBP binding loops; other site
701347012115	ABC-ATPase subunit interface; other site
701347012116	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
701347012117	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
701347012118	Walker A/P-loop; other site
701347012119	ATP binding site [chemical binding]; other site
701347012120	Q-loop/lid; other site
701347012121	ABC transporter signature motif; other site
701347012122	Walker B; other site
701347012123	D-loop; other site
701347012124	H-loop/switch region; other site
701347012125	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
701347012126	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
701347012127	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
701347012128	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
701347012129	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012130	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012131	ribulokinase; Provisional; Region: PRK04123
701347012132	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
701347012133	N- and C-terminal domain interface [polypeptide binding]; other site
701347012134	active site
701347012135	MgATP binding site [chemical binding]; other site
701347012136	catalytic site [active]
701347012137	metal binding site [ion binding]; metal-binding site
701347012138	carbohydrate binding site [chemical binding]; other site
701347012139	homodimer interface [polypeptide binding]; other site
701347012140	L-arabinose isomerase; Provisional; Region: PRK02929
701347012141	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
701347012142	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
701347012143	trimer interface [polypeptide binding]; other site
701347012144	putative substrate binding site [chemical binding]; other site
701347012145	putative metal binding site [ion binding]; other site
701347012146	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
701347012147	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
701347012148	intersubunit interface [polypeptide binding]; other site
701347012149	active site
701347012150	Zn2+ binding site [ion binding]; other site
701347012151	DNA polymerase II; Reviewed; Region: PRK05762
701347012152	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
701347012153	active site
701347012154	catalytic site [active]
701347012155	substrate binding site [chemical binding]; other site
701347012156	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
701347012157	active site
701347012158	metal-binding site
701347012159	ATP-dependent helicase HepA; Validated; Region: PRK04914
701347012160	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347012161	ATP binding site [chemical binding]; other site
701347012162	putative Mg++ binding site [ion binding]; other site
701347012163	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347012164	nucleotide binding region [chemical binding]; other site
701347012165	ATP-binding site [chemical binding]; other site
701347012166	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
701347012167	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
701347012168	active site
701347012169	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
701347012170	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
701347012171	putative metal binding site [ion binding]; other site
701347012172	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
701347012173	HSP70 interaction site [polypeptide binding]; other site
701347012174	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
701347012175	OstA-like protein; Region: OstA; pfam03968
701347012176	Organic solvent tolerance protein; Region: OstA_C; pfam04453
701347012177	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
701347012178	SurA N-terminal domain; Region: SurA_N; pfam09312
701347012179	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
701347012180	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
701347012181	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
701347012182	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
701347012183	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
701347012184	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
701347012185	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
701347012186	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
701347012187	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
701347012188	active site
701347012189	metal binding site [ion binding]; metal-binding site
701347012190	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
701347012191	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
701347012192	folate binding site [chemical binding]; other site
701347012193	NADP+ binding site [chemical binding]; other site
701347012194	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
701347012195	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
701347012196	TrkA-N domain; Region: TrkA_N; pfam02254
701347012197	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
701347012198	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347012199	D-galactonate transporter; Region: 2A0114; TIGR00893
701347012200	putative substrate translocation pore; other site
701347012201	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
701347012202	Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156
701347012203	putative ligand binding site [chemical binding]; other site
701347012204	NAD binding site [chemical binding]; other site
701347012205	catalytic site [active]
701347012206	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
701347012207	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347012208	DNA binding site [nucleotide binding]
701347012209	domain linker motif; other site
701347012210	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
701347012211	putative ligand binding site [chemical binding]; other site
701347012212	putative dimerization interface [polypeptide binding]; other site
701347012213	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
701347012214	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
701347012215	NADP binding site [chemical binding]; other site
701347012216	homodimer interface [polypeptide binding]; other site
701347012217	active site
701347012218	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
701347012219	ATP-binding site [chemical binding]; other site
701347012220	Gluconate-6-phosphate binding site [chemical binding]; other site
701347012221	Shikimate kinase; Region: SKI; pfam01202
701347012222	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
701347012223	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
701347012224	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
701347012225	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
701347012226	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
701347012227	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
701347012228	ATP-grasp domain; Region: ATP-grasp_4; cl17255
701347012229	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
701347012230	IMP binding site; other site
701347012231	dimer interface [polypeptide binding]; other site
701347012232	interdomain contacts; other site
701347012233	partial ornithine binding site; other site
701347012234	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
701347012235	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
701347012236	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
701347012237	catalytic site [active]
701347012238	subunit interface [polypeptide binding]; other site
701347012239	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
701347012240	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
701347012241	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
701347012242	Transcriptional regulators [Transcription]; Region: PurR; COG1609
701347012243	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347012244	DNA binding site [nucleotide binding]
701347012245	domain linker motif; other site
701347012246	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
701347012247	putative ligand binding site [chemical binding]; other site
701347012248	putative dimerization interface [polypeptide binding]; other site
701347012249	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
701347012250	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
701347012251	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
701347012252	active site
701347012253	active pocket/dimerization site; other site
701347012254	phosphorylation site [posttranslational modification]
701347012255	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
701347012256	active site
701347012257	phosphorylation site [posttranslational modification]
701347012258	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
701347012259	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
701347012260	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
701347012261	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
701347012262	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
701347012263	active site
701347012264	tetramer interface [polypeptide binding]; other site
701347012265	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
701347012266	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
701347012267	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
701347012268	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
701347012269	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
701347012270	lipoprotein signal peptidase; Provisional; Region: PRK14787
701347012271	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
701347012272	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
701347012273	HIGH motif; other site
701347012274	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
701347012275	active site
701347012276	KMSKS motif; other site
701347012277	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
701347012278	tRNA binding surface [nucleotide binding]; other site
701347012279	anticodon binding site; other site
701347012280	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
701347012281	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
701347012282	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
701347012283	active site
701347012284	Riboflavin kinase; Region: Flavokinase; smart00904
701347012285	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
701347012286	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347012287	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
701347012288	putative dimerization interface [polypeptide binding]; other site
701347012289	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
701347012290	chaperone protein DnaJ; Provisional; Region: PRK10767
701347012291	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
701347012292	HSP70 interaction site [polypeptide binding]; other site
701347012293	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
701347012294	substrate binding site [polypeptide binding]; other site
701347012295	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
701347012296	Zn binding sites [ion binding]; other site
701347012297	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
701347012298	dimer interface [polypeptide binding]; other site
701347012299	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
701347012300	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
701347012301	nucleotide binding site [chemical binding]; other site
701347012302	hypothetical protein; Provisional; Region: PRK10659
701347012303	metabolite-proton symporter; Region: 2A0106; TIGR00883
701347012304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347012305	putative substrate translocation pore; other site
701347012306	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
701347012307	MPT binding site; other site
701347012308	trimer interface [polypeptide binding]; other site
701347012309	transaldolase-like protein; Provisional; Region: PTZ00411
701347012310	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
701347012311	active site
701347012312	dimer interface [polypeptide binding]; other site
701347012313	catalytic residue [active]
701347012314	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
701347012315	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
701347012316	hypothetical protein; Validated; Region: PRK02101
701347012317	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
701347012318	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
701347012319	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
701347012320	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347012321	catalytic residue [active]
701347012322	homoserine kinase; Provisional; Region: PRK01212
701347012323	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
701347012324	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
701347012325	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
701347012326	putative catalytic residues [active]
701347012327	putative nucleotide binding site [chemical binding]; other site
701347012328	putative aspartate binding site [chemical binding]; other site
701347012329	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
701347012330	dimer interface [polypeptide binding]; other site
701347012331	putative threonine allosteric regulatory site; other site
701347012332	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
701347012333	putative threonine allosteric regulatory site; other site
701347012334	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
701347012335	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
701347012336	putative RNA methyltransferase; Provisional; Region: PRK10433
701347012337	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
701347012338	two-component response regulator; Provisional; Region: PRK11173
701347012339	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347012340	active site
701347012341	phosphorylation site [posttranslational modification]
701347012342	intermolecular recognition site; other site
701347012343	dimerization interface [polypeptide binding]; other site
701347012344	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347012345	DNA binding site [nucleotide binding]
701347012346	Predicted acyl esterases [General function prediction only]; Region: COG2936
701347012347	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
701347012348	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
701347012349	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347012350	Walker A/P-loop; other site
701347012351	ATP binding site [chemical binding]; other site
701347012352	Q-loop/lid; other site
701347012353	ABC transporter signature motif; other site
701347012354	Walker B; other site
701347012355	D-loop; other site
701347012356	H-loop/switch region; other site
701347012357	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347012358	Walker A/P-loop; other site
701347012359	ATP binding site [chemical binding]; other site
701347012360	Q-loop/lid; other site
701347012361	ABC transporter signature motif; other site
701347012362	Walker B; other site
701347012363	D-loop; other site
701347012364	H-loop/switch region; other site
701347012365	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
701347012366	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
701347012367	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347012368	dimer interface [polypeptide binding]; other site
701347012369	conserved gate region; other site
701347012370	putative PBP binding loops; other site
701347012371	ABC-ATPase subunit interface; other site
701347012372	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
701347012373	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347012374	dimer interface [polypeptide binding]; other site
701347012375	conserved gate region; other site
701347012376	ABC-ATPase subunit interface; other site
701347012377	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
701347012378	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
701347012379	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
701347012380	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347012381	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347012382	dimerization interface [polypeptide binding]; other site
701347012383	hypothetical protein; Provisional; Region: PRK10756
701347012384	CreA protein; Region: CreA; pfam05981
701347012385	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
701347012386	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012387	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
701347012388	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
701347012389	catalytic core [active]
701347012390	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
701347012391	Trp operon repressor; Provisional; Region: PRK01381
701347012392	lytic murein transglycosylase; Provisional; Region: PRK11619
701347012393	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347012394	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347012395	catalytic residue [active]
701347012396	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
701347012397	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347012398	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347012399	ABC transporter; Region: ABC_tran_2; pfam12848
701347012400	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
701347012401	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
701347012402	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
701347012403	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
701347012404	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
701347012405	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
701347012406	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
701347012407	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
701347012408	active site
701347012409	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
701347012410	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
701347012411	Protein of unknown function (DUF3184); Region: DUF3184; pfam11380
701347012412	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
701347012413	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
701347012414	Walker A/P-loop; other site
701347012415	ATP binding site [chemical binding]; other site
701347012416	Q-loop/lid; other site
701347012417	ABC transporter signature motif; other site
701347012418	Walker B; other site
701347012419	D-loop; other site
701347012420	H-loop/switch region; other site
701347012421	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
701347012422	ABC-2 type transporter; Region: ABC2_membrane; cl17235
701347012423	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347012424	non-specific DNA binding site [nucleotide binding]; other site
701347012425	salt bridge; other site
701347012426	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
701347012427	sequence-specific DNA binding site [nucleotide binding]; other site
701347012428	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
701347012429	active site
701347012430	(T/H)XGH motif; other site
701347012431	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
701347012432	DNA repair protein RadA; Region: sms; TIGR00416
701347012433	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
701347012434	Walker A motif/ATP binding site; other site
701347012435	ATP binding site [chemical binding]; other site
701347012436	Walker B motif; other site
701347012437	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
701347012438	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
701347012439	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347012440	motif I; other site
701347012441	motif II; other site
701347012442	hypothetical protein; Provisional; Region: PRK11246
701347012443	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
701347012444	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
701347012445	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
701347012446	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
701347012447	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
701347012448	phosphopentomutase; Provisional; Region: PRK05362
701347012449	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
701347012450	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
701347012451	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
701347012452	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
701347012453	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
701347012454	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
701347012455	intersubunit interface [polypeptide binding]; other site
701347012456	active site
701347012457	catalytic residue [active]
701347012458	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
701347012459	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347012460	FeS/SAM binding site; other site
701347012461	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
701347012462	active site
701347012463	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
701347012464	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
701347012465	active site
701347012466	nucleophile elbow; other site
701347012467	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
701347012468	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
701347012469	G1 box; other site
701347012470	putative GEF interaction site [polypeptide binding]; other site
701347012471	GTP/Mg2+ binding site [chemical binding]; other site
701347012472	Switch I region; other site
701347012473	G2 box; other site
701347012474	G3 box; other site
701347012475	Switch II region; other site
701347012476	G4 box; other site
701347012477	G5 box; other site
701347012478	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
701347012479	dUMP phosphatase; Provisional; Region: PRK09449
701347012480	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347012481	motif II; other site
701347012482	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
701347012483	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347012484	Coenzyme A binding pocket [chemical binding]; other site
701347012485	DNA polymerase III subunit psi; Validated; Region: PRK06856
701347012486	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
701347012487	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
701347012488	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347012489	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
701347012490	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
701347012491	metal binding site [ion binding]; metal-binding site
701347012492	active site
701347012493	I-site; other site
701347012494	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
701347012495	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
701347012496	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
701347012497	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
701347012498	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
701347012499	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
701347012500	putative deacylase active site [active]
701347012501	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
701347012502	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347012503	DNA binding residues [nucleotide binding]
701347012504	dimerization interface [polypeptide binding]; other site
701347012505	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347012506	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347012507	DNA binding residues [nucleotide binding]
701347012508	dimerization interface [polypeptide binding]; other site
701347012509	Uncharacterized conserved protein [Function unknown]; Region: COG2966
701347012510	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
701347012511	hypothetical protein; Provisional; Region: PRK09917
701347012512	primosomal protein DnaI; Provisional; Region: PRK02854
701347012513	DNA replication protein DnaC; Validated; Region: PRK07952
701347012514	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347012515	Walker A motif; other site
701347012516	ATP binding site [chemical binding]; other site
701347012517	Walker B motif; other site
701347012518	hypothetical protein; Provisional; Region: PRK11667
701347012519	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
701347012520	Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154
701347012521	tetramer interface [polypeptide binding]; other site
701347012522	heme binding pocket [chemical binding]; other site
701347012523	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
701347012524	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
701347012525	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
701347012526	phosphoglycerol transferase I; Provisional; Region: PRK03776
701347012527	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
701347012528	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347012529	Coenzyme A binding pocket [chemical binding]; other site
701347012530	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
701347012531	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
701347012532	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347012533	Coenzyme A binding pocket [chemical binding]; other site
701347012534	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
701347012535	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
701347012536	dimer interface [polypeptide binding]; other site
701347012537	ligand binding site [chemical binding]; other site
701347012538	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347012539	dimerization interface [polypeptide binding]; other site
701347012540	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347012541	dimer interface [polypeptide binding]; other site
701347012542	putative CheW interface [polypeptide binding]; other site
701347012543	carbon starvation protein A; Provisional; Region: PRK15015
701347012544	Carbon starvation protein CstA; Region: CstA; pfam02554
701347012545	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
701347012546	Uncharacterized small protein [Function unknown]; Region: COG2879
701347012547	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
701347012548	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
701347012549	P-loop, Walker A motif; other site
701347012550	Base recognition motif; other site
701347012551	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
701347012552	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
701347012553	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
701347012554	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
701347012555	Penicillin G acylase (PGA) is the key enzyme in the industrial production of beta-lactam antibiotics. PGA hydrolyzes the side chain of penicillin G and related beta-lactam antibiotics releasing 6-amino penicillanic acid (6-APA), a building block in the...; Region: Ntn_PGA; cd03748
701347012556	active site
701347012557	purine nucleoside phosphorylase; Provisional; Region: PRK08202
701347012558	putative transporter; Provisional; Region: PRK03699
701347012559	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
701347012560	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347012561	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
701347012562	dimerization interface [polypeptide binding]; other site
701347012563	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
701347012564	amino acid transporter; Region: 2A0306; TIGR00909
701347012565	Spore germination protein; Region: Spore_permease; cl17796
701347012566	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
701347012567	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
701347012568	dimer interface [polypeptide binding]; other site
701347012569	NADP binding site [chemical binding]; other site
701347012570	catalytic residues [active]
701347012571	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
701347012572	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
701347012573	inhibitor site; inhibition site
701347012574	active site
701347012575	dimer interface [polypeptide binding]; other site
701347012576	catalytic residue [active]
701347012577	PAS fold; Region: PAS_4; pfam08448
701347012578	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
701347012579	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012580	hydroxyproline-2-epimerase; Provisional; Region: PRK13970
701347012581	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
701347012582	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
701347012583	hydroxyglutarate oxidase; Provisional; Region: PRK11728
701347012584	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510
701347012585	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
701347012586	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
701347012587	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
701347012588	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
701347012589	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
701347012590	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
701347012591	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
701347012592	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
701347012593	NAD binding site [chemical binding]; other site
701347012594	catalytic residues [active]
701347012595	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
701347012596	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
701347012597	putative active site [active]
701347012598	putative metal binding site [ion binding]; other site
701347012599	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
701347012600	putative substrate binding pocket [chemical binding]; other site
701347012601	trimer interface [polypeptide binding]; other site
701347012602	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
701347012603	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
701347012604	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
701347012605	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347012606	putative substrate translocation pore; other site
701347012607	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
701347012608	Cupin domain; Region: Cupin_2; pfam07883
701347012609	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012610	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
701347012611	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
701347012612	Flavin Reductases; Region: FlaRed; cl00801
701347012613	Domain of unknown function (DUF1127); Region: DUF1127; pfam06568
701347012614	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
701347012615	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347012616	DNA-binding site [nucleotide binding]; DNA binding site
701347012617	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347012618	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347012619	homodimer interface [polypeptide binding]; other site
701347012620	catalytic residue [active]
701347012621	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
701347012622	FosA, a Fosfomycin resistance protein, catalyzes the addition of glutathione to the antibiotic fosfomycin, making it inactive; Region: FosA; cd07244
701347012623	dimer interface [polypeptide binding]; other site
701347012624	Mn binding site [ion binding]; other site
701347012625	K binding site [ion binding]; other site
701347012626	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
701347012627	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347012628	Walker A motif; other site
701347012629	ATP binding site [chemical binding]; other site
701347012630	Walker B motif; other site
701347012631	arginine finger; other site
701347012632	Transcriptional antiterminator [Transcription]; Region: COG3933
701347012633	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
701347012634	active site
701347012635	active pocket/dimerization site; other site
701347012636	phosphorylation site [posttranslational modification]
701347012637	PRD domain; Region: PRD; pfam00874
701347012638	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
701347012639	active pocket/dimerization site; other site
701347012640	active site
701347012641	phosphorylation site [posttranslational modification]
701347012642	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
701347012643	active site
701347012644	phosphorylation site [posttranslational modification]
701347012645	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
701347012646	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
701347012647	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
701347012648	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
701347012649	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
701347012650	hypothetical protein; Provisional; Region: PRK13687
701347012651	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
701347012652	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347012653	S-adenosylmethionine binding site [chemical binding]; other site
701347012654	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347012655	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347012656	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_3; cd08461
701347012657	putative substrate binding pocket [chemical binding]; other site
701347012658	putative dimerization interface [polypeptide binding]; other site
701347012659	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
701347012660	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
701347012661	Uncharacterized conserved protein [Function unknown]; Region: COG2850
701347012662	Glycogen synthesis protein; Region: GlgS; cl11663
701347012663	Transcriptional regulators [Transcription]; Region: FadR; COG2186
701347012664	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347012665	DNA-binding site [nucleotide binding]; DNA binding site
701347012666	FCD domain; Region: FCD; pfam07729
701347012667	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
701347012668	permease, urea carboxylase system; Region: ureacarb_perm; TIGR03428
701347012669	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
701347012670	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
701347012671	Predicted membrane protein [Function unknown]; Region: COG3326
701347012672	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
701347012673	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
701347012674	Protein of unknown function (DUF987); Region: DUF987; pfam06174
701347012675	hypothetical protein; Reviewed; Region: PRK00024
701347012676	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
701347012677	MPN+ (JAMM) motif; other site
701347012678	Zinc-binding site [ion binding]; other site
701347012679	Antirestriction protein; Region: Antirestrict; pfam03230
701347012680	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
701347012681	Inhibitor of vertebrate lysozyme (Ivy); Region: Ivy; cl07428
701347012682	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
701347012683	Predicted transcriptional regulator [Transcription]; Region: COG2378
701347012684	WYL domain; Region: WYL; cl14852
701347012685	Domain of unknown function (DUF932); Region: DUF932; pfam06067
701347012686	Predicted GTPase [General function prediction only]; Region: COG3596
701347012687	YfjP GTPase; Region: YfjP; cd11383
701347012688	G1 box; other site
701347012689	GTP/Mg2+ binding site [chemical binding]; other site
701347012690	Switch I region; other site
701347012691	G2 box; other site
701347012692	Switch II region; other site
701347012693	G3 box; other site
701347012694	G4 box; other site
701347012695	G5 box; other site
701347012696	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
701347012697	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
701347012698	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
701347012699	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
701347012700	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
701347012701	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
701347012702	MgtC family; Region: MgtC; pfam02308
701347012703	Fimbrial protein; Region: Fimbrial; cl01416
701347012704	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
701347012705	PapC N-terminal domain; Region: PapC_N; pfam13954
701347012706	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347012707	PapC C-terminal domain; Region: PapC_C; pfam13953
701347012708	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
701347012709	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347012710	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347012711	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
701347012712	transcriptional activator SprB; Provisional; Region: PRK15320
701347012713	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
701347012714	ParB-like nuclease domain; Region: ParBc; cl02129
701347012715	Restriction endonuclease; Region: Mrr_cat; pfam04471
701347012716	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
701347012717	active site
701347012718	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347012719	ATP binding site [chemical binding]; other site
701347012720	putative Mg++ binding site [ion binding]; other site
701347012721	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
701347012722	nucleotide binding region [chemical binding]; other site
701347012723	ATP-binding site [chemical binding]; other site
701347012724	DEAD-like helicases superfamily; Region: DEXDc; smart00487
701347012725	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347012726	ATP binding site [chemical binding]; other site
701347012727	putative Mg++ binding site [ion binding]; other site
701347012728	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347012729	nucleotide binding region [chemical binding]; other site
701347012730	ATP-binding site [chemical binding]; other site
701347012731	DEAD/DEAH box helicase; Region: DEAD; pfam00270
701347012732	ATP binding site [chemical binding]; other site
701347012733	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347012734	putative Mg++ binding site [ion binding]; other site
701347012735	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347012736	ATP-binding site [chemical binding]; other site
701347012737	PLD-like domain; Region: PLDc_2; pfam13091
701347012738	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
701347012739	putative active site [active]
701347012740	catalytic site [active]
701347012741	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
701347012742	putative active site [active]
701347012743	DGQHR domain; Region: DGQHR; TIGR03187
701347012744	DNA phosphorothioation-associated DGQHR protein 1; Region: DGQHR_dnd_1; TIGR04172
701347012745	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
701347012746	integrase; Provisional; Region: PRK09692
701347012747	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
701347012748	active site
701347012749	Int/Topo IB signature motif; other site
701347012750	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
701347012751	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
701347012752	putative NAD(P) binding site [chemical binding]; other site
701347012753	putative substrate binding site [chemical binding]; other site
701347012754	catalytic Zn binding site [ion binding]; other site
701347012755	structural Zn binding site [ion binding]; other site
701347012756	dimer interface [polypeptide binding]; other site
701347012757	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347012758	dimer interface [polypeptide binding]; other site
701347012759	conserved gate region; other site
701347012760	putative PBP binding loops; other site
701347012761	ABC-ATPase subunit interface; other site
701347012762	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
701347012763	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347012764	dimer interface [polypeptide binding]; other site
701347012765	conserved gate region; other site
701347012766	putative PBP binding loops; other site
701347012767	ABC-ATPase subunit interface; other site
701347012768	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
701347012769	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
701347012770	active site
701347012771	metal binding site [ion binding]; metal-binding site
701347012772	hexamer interface [polypeptide binding]; other site
701347012773	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
701347012774	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
701347012775	Walker A/P-loop; other site
701347012776	ATP binding site [chemical binding]; other site
701347012777	Q-loop/lid; other site
701347012778	ABC transporter signature motif; other site
701347012779	Walker B; other site
701347012780	D-loop; other site
701347012781	H-loop/switch region; other site
701347012782	TOBE domain; Region: TOBE_2; pfam08402
701347012783	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
701347012784	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
701347012785	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
701347012786	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
701347012787	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
701347012788	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
701347012789	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
701347012790	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
701347012791	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
701347012792	multifunctional aminopeptidase A; Provisional; Region: PRK00913
701347012793	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
701347012794	interface (dimer of trimers) [polypeptide binding]; other site
701347012795	Substrate-binding/catalytic site; other site
701347012796	Zn-binding sites [ion binding]; other site
701347012797	DNA polymerase III subunit chi; Validated; Region: PRK05728
701347012798	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
701347012799	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
701347012800	HIGH motif; other site
701347012801	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
701347012802	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
701347012803	active site
701347012804	KMSKS motif; other site
701347012805	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
701347012806	tRNA binding surface [nucleotide binding]; other site
701347012807	anticodon binding site; other site
701347012808	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
701347012809	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347012810	Coenzyme A binding pocket [chemical binding]; other site
701347012811	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
701347012812	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
701347012813	active site
701347012814	dinuclear metal binding site [ion binding]; other site
701347012815	dimerization interface [polypeptide binding]; other site
701347012816	RNase E inhibitor protein; Provisional; Region: PRK11191
701347012817	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
701347012818	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
701347012819	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
701347012820	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
701347012821	arginine deiminase; Provisional; Region: PRK01388
701347012822	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
701347012823	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
701347012824	putative substrate binding site [chemical binding]; other site
701347012825	nucleotide binding site [chemical binding]; other site
701347012826	nucleotide binding site [chemical binding]; other site
701347012827	homodimer interface [polypeptide binding]; other site
701347012828	ornithine carbamoyltransferase; Validated; Region: PRK02102
701347012829	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
701347012830	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
701347012831	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
701347012832	Arginine repressor [Transcription]; Region: ArgR; COG1438
701347012833	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
701347012834	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
701347012835	pyrBI operon leader peptide; Provisional; Region: PRK10224
701347012836	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
701347012837	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
701347012838	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
701347012839	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
701347012840	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
701347012841	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
701347012842	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
701347012843	homotrimer interaction site [polypeptide binding]; other site
701347012844	putative active site [active]
701347012845	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
701347012846	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
701347012847	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
701347012848	active site
701347012849	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
701347012850	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
701347012851	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
701347012852	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
701347012853	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
701347012854	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347012855	motif II; other site
701347012856	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
701347012857	trehalose repressor; Provisional; Region: treR; PRK09492
701347012858	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347012859	DNA binding site [nucleotide binding]
701347012860	domain linker motif; other site
701347012861	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
701347012862	dimerization interface [polypeptide binding]; other site
701347012863	ligand binding site [chemical binding]; other site
701347012864	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
701347012865	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
701347012866	active site turn [active]
701347012867	phosphorylation site [posttranslational modification]
701347012868	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
701347012869	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
701347012870	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
701347012871	Ca binding site [ion binding]; other site
701347012872	active site
701347012873	catalytic site [active]
701347012874	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
701347012875	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
701347012876	ATP cone domain; Region: ATP-cone; pfam03477
701347012877	Class III ribonucleotide reductase; Region: RNR_III; cd01675
701347012878	effector binding site; other site
701347012879	active site
701347012880	Zn binding site [ion binding]; other site
701347012881	glycine loop; other site
701347012882	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
701347012883	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347012884	FeS/SAM binding site; other site
701347012885	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
701347012886	HTH domain; Region: HTH_11; pfam08279
701347012887	Mga helix-turn-helix domain; Region: Mga; pfam05043
701347012888	PRD domain; Region: PRD; pfam00874
701347012889	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
701347012890	active site
701347012891	P-loop; other site
701347012892	phosphorylation site [posttranslational modification]
701347012893	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347012894	active site
701347012895	phosphorylation site [posttranslational modification]
701347012896	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
701347012897	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
701347012898	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
701347012899	dihydroorotase; Provisional; Region: PRK09237
701347012900	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
701347012901	active site
701347012902	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
701347012903	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
701347012904	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
701347012905	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; pfam14272
701347012906	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
701347012907	Cytochrome b562; Region: Cytochrom_B562; cl01546
701347012908	peptidase PmbA; Provisional; Region: PRK11040
701347012909	hypothetical protein; Provisional; Region: PRK05255
701347012910	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
701347012911	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
701347012912	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
701347012913	Protein of unknown function (DUF1318); Region: DUF1318; cl01547
701347012914	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
701347012915	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
701347012916	AMP binding site [chemical binding]; other site
701347012917	metal binding site [ion binding]; metal-binding site
701347012918	active site
701347012919	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347012920	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347012921	dimer interface [polypeptide binding]; other site
701347012922	putative CheW interface [polypeptide binding]; other site
701347012923	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347012924	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347012925	TM-ABC transporter signature motif; other site
701347012926	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347012927	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347012928	TM-ABC transporter signature motif; other site
701347012929	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347012930	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347012931	Walker A/P-loop; other site
701347012932	ATP binding site [chemical binding]; other site
701347012933	Q-loop/lid; other site
701347012934	ABC transporter signature motif; other site
701347012935	Walker B; other site
701347012936	D-loop; other site
701347012937	H-loop/switch region; other site
701347012938	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347012939	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
701347012940	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
701347012941	putative ligand binding site [chemical binding]; other site
701347012942	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
701347012943	dimer interface [polypeptide binding]; other site
701347012944	substrate binding site [chemical binding]; other site
701347012945	metal binding sites [ion binding]; metal-binding site
701347012946	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347012947	dimerization interface [polypeptide binding]; other site
701347012948	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
701347012949	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
701347012950	dimer interface [polypeptide binding]; other site
701347012951	putative CheW interface [polypeptide binding]; other site
701347012952	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
701347012953	putative active site pocket [active]
701347012954	dimerization interface [polypeptide binding]; other site
701347012955	putative catalytic residue [active]
701347012956	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
701347012957	Family of unknown function (DUF490); Region: DUF490; pfam04357
701347012958	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
701347012959	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
701347012960	Surface antigen; Region: Bac_surface_Ag; pfam01103
701347012961	methionine sulfoxide reductase A; Provisional; Region: PRK00058
701347012962	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
701347012963	Domain of unknown function DUF21; Region: DUF21; pfam01595
701347012964	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
701347012965	Transporter associated domain; Region: CorC_HlyC; smart01091
701347012966	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
701347012967	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
701347012968	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
701347012969	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
701347012970	metal binding site [ion binding]; metal-binding site
701347012971	dimer interface [polypeptide binding]; other site
701347012972	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
701347012973	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
701347012974	active site
701347012975	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
701347012976	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
701347012977	active site
701347012978	metal binding site [ion binding]; metal-binding site
701347012979	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
701347012980	Predicted transcriptional regulators [Transcription]; Region: COG1733
701347012981	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
701347012982	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
701347012983	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
701347012984	NADP binding site [chemical binding]; other site
701347012985	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
701347012986	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012987	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
701347012988	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347012989	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
701347012990	EamA-like transporter family; Region: EamA; pfam00892
701347012991	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
701347012992	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
701347012993	Hemerythrin-like domain; Region: Hr-like; cd12108
701347012994	Fe binding site [ion binding]; other site
701347012995	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
701347012996	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
701347012997	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
701347012998	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
701347012999	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
701347013000	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
701347013001	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
701347013002	EamA-like transporter family; Region: EamA; pfam00892
701347013003	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
701347013004	EamA-like transporter family; Region: EamA; pfam00892
701347013005	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
701347013006	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
701347013007	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
701347013008	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
701347013009	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
701347013010	dimer interface [polypeptide binding]; other site
701347013011	ssDNA binding site [nucleotide binding]; other site
701347013012	tetramer (dimer of dimers) interface [polypeptide binding]; other site
701347013013	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
701347013014	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347013015	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
701347013016	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
701347013017	intersubunit interface [polypeptide binding]; other site
701347013018	active site
701347013019	Zn2+ binding site [ion binding]; other site
701347013020	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
701347013021	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
701347013022	AP (apurinic/apyrimidinic) site pocket; other site
701347013023	DNA interaction; other site
701347013024	Metal-binding active site; metal-binding site
701347013025	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
701347013026	active site
701347013027	dimer interface [polypeptide binding]; other site
701347013028	magnesium binding site [ion binding]; other site
701347013029	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347013030	active site
701347013031	phosphorylation site [posttranslational modification]
701347013032	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
701347013033	active site
701347013034	P-loop; other site
701347013035	phosphorylation site [posttranslational modification]
701347013036	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
701347013037	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
701347013038	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
701347013039	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
701347013040	transcriptional repressor UlaR; Provisional; Region: PRK13509
701347013041	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
701347013042	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347013043	esterase; Provisional; Region: PRK10566
701347013044	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
701347013045	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
701347013046	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
701347013047	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
701347013048	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
701347013049	FAD binding site [chemical binding]; other site
701347013050	substrate binding site [chemical binding]; other site
701347013051	catalytic residues [active]
701347013052	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
701347013053	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
701347013054	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
701347013055	exoribonuclease R; Provisional; Region: PRK11642
701347013056	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
701347013057	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
701347013058	RNB domain; Region: RNB; pfam00773
701347013059	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
701347013060	RNA binding site [nucleotide binding]; other site
701347013061	Predicted transcriptional regulator [Transcription]; Region: COG1959
701347013062	transcriptional repressor NsrR; Provisional; Region: PRK11014
701347013063	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
701347013064	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
701347013065	GDP-binding site [chemical binding]; other site
701347013066	ACT binding site; other site
701347013067	IMP binding site; other site
701347013068	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
701347013069	FtsH protease regulator HflC; Provisional; Region: PRK11029
701347013070	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
701347013071	FtsH protease regulator HflK; Provisional; Region: PRK10930
701347013072	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
701347013073	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
701347013074	GTPase HflX; Provisional; Region: PRK11058
701347013075	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
701347013076	HflX GTPase family; Region: HflX; cd01878
701347013077	G1 box; other site
701347013078	GTP/Mg2+ binding site [chemical binding]; other site
701347013079	Switch I region; other site
701347013080	G2 box; other site
701347013081	G3 box; other site
701347013082	Switch II region; other site
701347013083	G4 box; other site
701347013084	G5 box; other site
701347013085	bacterial Hfq-like; Region: Hfq; cd01716
701347013086	hexamer interface [polypeptide binding]; other site
701347013087	Sm1 motif; other site
701347013088	RNA binding site [nucleotide binding]; other site
701347013089	Sm2 motif; other site
701347013090	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
701347013091	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
701347013092	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
701347013093	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347013094	ATP binding site [chemical binding]; other site
701347013095	Mg2+ binding site [ion binding]; other site
701347013096	G-X-G motif; other site
701347013097	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
701347013098	ATP binding site [chemical binding]; other site
701347013099	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
701347013100	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
701347013101	AMIN domain; Region: AMIN; pfam11741
701347013102	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
701347013103	active site
701347013104	metal binding site [ion binding]; metal-binding site
701347013105	ADP-binding protein; Provisional; Region: PRK10646
701347013106	putative carbohydrate kinase; Provisional; Region: PRK10565
701347013107	Uncharacterized conserved protein [Function unknown]; Region: COG0062
701347013108	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
701347013109	putative substrate binding site [chemical binding]; other site
701347013110	putative ATP binding site [chemical binding]; other site
701347013111	epoxyqueuosine reductase; Region: TIGR00276
701347013112	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
701347013113	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
701347013114	catalytic site [active]
701347013115	putative active site [active]
701347013116	putative substrate binding site [chemical binding]; other site
701347013117	dimer interface [polypeptide binding]; other site
701347013118	GTPase RsgA; Reviewed; Region: PRK12288
701347013119	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
701347013120	RNA binding site [nucleotide binding]; other site
701347013121	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
701347013122	GTPase/Zn-binding domain interface [polypeptide binding]; other site
701347013123	GTP/Mg2+ binding site [chemical binding]; other site
701347013124	G4 box; other site
701347013125	G5 box; other site
701347013126	G1 box; other site
701347013127	Switch I region; other site
701347013128	G2 box; other site
701347013129	G3 box; other site
701347013130	Switch II region; other site
701347013131	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
701347013132	putative mechanosensitive channel protein; Provisional; Region: PRK10929
701347013133	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
701347013134	Mechanosensitive ion channel; Region: MS_channel; pfam00924
701347013135	poxB regulator PoxA; Provisional; Region: PRK09350
701347013136	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
701347013137	motif 1; other site
701347013138	dimer interface [polypeptide binding]; other site
701347013139	active site
701347013140	motif 2; other site
701347013141	motif 3; other site
701347013142	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
701347013143	L-aspartate oxidase; Provisional; Region: PRK06175
701347013144	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
701347013145	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
701347013146	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
701347013147	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
701347013148	D-subunit interface [polypeptide binding]; other site
701347013149	Iron-sulfur protein interface; other site
701347013150	proximal quinone binding site [chemical binding]; other site
701347013151	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
701347013152	Iron-sulfur protein interface; other site
701347013153	proximal quinone binding site [chemical binding]; other site
701347013154	C-subunit interface; other site
701347013155	distal quinone binding site; other site
701347013156	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
701347013157	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
701347013158	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
701347013159	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
701347013160	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
701347013161	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347013162	DNA binding residues [nucleotide binding]
701347013163	dimerization interface [polypeptide binding]; other site
701347013164	Entericidin EcnA/B family; Region: Entericidin; cl02322
701347013165	entericidin A; Provisional; Region: PRK09810
701347013166	elongation factor P; Validated; Region: PRK00529
701347013167	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
701347013168	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
701347013169	RNA binding site [nucleotide binding]; other site
701347013170	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
701347013171	RNA binding site [nucleotide binding]; other site
701347013172	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
701347013173	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347013174	FeS/SAM binding site; other site
701347013175	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
701347013176	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
701347013177	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
701347013178	ring oligomerisation interface [polypeptide binding]; other site
701347013179	ATP/Mg binding site [chemical binding]; other site
701347013180	stacking interactions; other site
701347013181	hinge regions; other site
701347013182	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
701347013183	oligomerisation interface [polypeptide binding]; other site
701347013184	mobile loop; other site
701347013185	roof hairpin; other site
701347013186	putative transporter; Provisional; Region: PRK11021
701347013187	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
701347013188	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
701347013189	Aspartase; Region: Aspartase; cd01357
701347013190	active sites [active]
701347013191	tetramer interface [polypeptide binding]; other site
701347013192	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
701347013193	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
701347013194	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
701347013195	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
701347013196	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
701347013197	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
701347013198	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
701347013199	DsbD alpha interface [polypeptide binding]; other site
701347013200	catalytic residues [active]
701347013201	putative transcriptional regulator; Provisional; Region: PRK11640
701347013202	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347013203	acyl-CoA synthetase; Validated; Region: PRK06839
701347013204	haemagglutination activity domain; Region: Haemagg_act; pfam05860
701347013205	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
701347013206	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
701347013207	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
701347013208	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
701347013209	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
701347013210	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
701347013211	RTX toxin acyltransferase family; Region: HlyC; pfam02794
701347013212	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
701347013213	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
701347013214	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
701347013215	Helix-turn-helix domain; Region: HTH_39; pfam14090
701347013216	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347013217	Walker A motif; other site
701347013218	ATP binding site [chemical binding]; other site
701347013219	Walker B motif; other site
701347013220	Transcriptional antiterminator [Transcription]; Region: COG3933
701347013221	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
701347013222	active pocket/dimerization site; other site
701347013223	active site
701347013224	phosphorylation site [posttranslational modification]
701347013225	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
701347013226	active pocket/dimerization site; other site
701347013227	active site
701347013228	phosphorylation site [posttranslational modification]
701347013229	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cl00021
701347013230	active site
701347013231	phosphorylation site [posttranslational modification]
701347013232	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
701347013233	active site
701347013234	phosphorylation site [posttranslational modification]
701347013235	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
701347013236	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
701347013237	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
701347013238	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
701347013239	active pocket/dimerization site; other site
701347013240	active site
701347013241	phosphorylation site [posttranslational modification]
701347013242	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
701347013243	active site
701347013244	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
701347013245	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
701347013246	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
701347013247	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
701347013248	TPR motif; other site
701347013249	binding surface
701347013250	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
701347013251	hypothetical protein; Provisional; Region: PRK09936
701347013252	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
701347013253	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
701347013254	Pyruvate formate lyase; Region: PFL; pfam02901
701347013255	Glycine radical; Region: Gly_radical; pfam01228
701347013256	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
701347013257	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347013258	active site
701347013259	phosphorylation site [posttranslational modification]
701347013260	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
701347013261	active site
701347013262	P-loop; other site
701347013263	phosphorylation site [posttranslational modification]
701347013264	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
701347013265	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
701347013266	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347013267	DNA-binding site [nucleotide binding]; DNA binding site
701347013268	UTRA domain; Region: UTRA; pfam07702
701347013269	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
701347013270	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
701347013271	HSP70 interaction site [polypeptide binding]; other site
701347013272	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
701347013273	substrate binding site [polypeptide binding]; other site
701347013274	dimer interface [polypeptide binding]; other site
701347013275	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
701347013276	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
701347013277	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
701347013278	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
701347013279	Protein of unknwon function (DUF2893); Region: DUF2893; pfam11459
701347013280	arginine decarboxylase; Provisional; Region: PRK15029
701347013281	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
701347013282	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
701347013283	homodimer interface [polypeptide binding]; other site
701347013284	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347013285	catalytic residue [active]
701347013286	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
701347013287	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
701347013288	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347013289	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
701347013290	Protein export membrane protein; Region: SecD_SecF; cl14618
701347013291	acid-resistance membrane protein; Provisional; Region: PRK10209
701347013292	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
701347013293	acid-resistance protein; Provisional; Region: PRK10208
701347013294	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
701347013295	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347013296	arginine:agmatin antiporter; Provisional; Region: PRK10644
701347013297	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
701347013298	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
701347013299	YjcZ-like protein; Region: YjcZ; pfam13990
701347013300	hypothetical protein; Provisional; Region: PRK09866
701347013301	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
701347013302	G1 box; other site
701347013303	GTP/Mg2+ binding site [chemical binding]; other site
701347013304	G2 box; other site
701347013305	Switch I region; other site
701347013306	G3 box; other site
701347013307	Switch II region; other site
701347013308	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
701347013309	G3 box; other site
701347013310	Switch II region; other site
701347013311	G4 box; other site
701347013312	G5 box; other site
701347013313	hypothetical protein; Provisional; Region: PRK10220
701347013314	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
701347013315	PhnA protein; Region: PhnA; pfam03831
701347013316	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
701347013317	dimer interface [polypeptide binding]; other site
701347013318	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
701347013319	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
701347013320	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347013321	DNA-binding site [nucleotide binding]; DNA binding site
701347013322	UTRA domain; Region: UTRA; pfam07702
701347013323	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
701347013324	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
701347013325	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
701347013326	Phosphonate metabolism protein PhnJ; Region: PhnJ; pfam06007
701347013327	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
701347013328	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
701347013329	Walker A/P-loop; other site
701347013330	ATP binding site [chemical binding]; other site
701347013331	Q-loop/lid; other site
701347013332	ABC transporter signature motif; other site
701347013333	Walker B; other site
701347013334	D-loop; other site
701347013335	H-loop/switch region; other site
701347013336	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
701347013337	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
701347013338	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
701347013339	Walker A/P-loop; other site
701347013340	ATP binding site [chemical binding]; other site
701347013341	Q-loop/lid; other site
701347013342	ABC transporter signature motif; other site
701347013343	Walker B; other site
701347013344	D-loop; other site
701347013345	H-loop/switch region; other site
701347013346	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
701347013347	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
701347013348	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
701347013349	active site
701347013350	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
701347013351	Guanylate kinase; Region: Guanylate_kin; pfam00625
701347013352	active site
701347013353	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347013354	Coenzyme A binding pocket [chemical binding]; other site
701347013355	putative hydrolase; Provisional; Region: PRK02113
701347013356	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
701347013357	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
701347013358	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347013359	dimerization interface [polypeptide binding]; other site
701347013360	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347013361	dimer interface [polypeptide binding]; other site
701347013362	phosphorylation site [posttranslational modification]
701347013363	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347013364	ATP binding site [chemical binding]; other site
701347013365	Mg2+ binding site [ion binding]; other site
701347013366	G-X-G motif; other site
701347013367	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347013368	Response regulator receiver domain; Region: Response_reg; pfam00072
701347013369	active site
701347013370	phosphorylation site [posttranslational modification]
701347013371	intermolecular recognition site; other site
701347013372	dimerization interface [polypeptide binding]; other site
701347013373	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347013374	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347013375	Walker A/P-loop; other site
701347013376	ATP binding site [chemical binding]; other site
701347013377	Q-loop/lid; other site
701347013378	ABC transporter signature motif; other site
701347013379	Walker B; other site
701347013380	D-loop; other site
701347013381	H-loop/switch region; other site
701347013382	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347013383	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347013384	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347013385	TM-ABC transporter signature motif; other site
701347013386	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
701347013387	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
701347013388	putative ligand binding site [chemical binding]; other site
701347013389	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
701347013390	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
701347013391	intersubunit interface [polypeptide binding]; other site
701347013392	active site
701347013393	zinc binding site [ion binding]; other site
701347013394	Na+ binding site [ion binding]; other site
701347013395	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
701347013396	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347013397	substrate binding site [chemical binding]; other site
701347013398	ATP binding site [chemical binding]; other site
701347013399	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
701347013400	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347013401	active site
701347013402	phosphorylation site [posttranslational modification]
701347013403	intermolecular recognition site; other site
701347013404	dimerization interface [polypeptide binding]; other site
701347013405	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347013406	DNA binding site [nucleotide binding]
701347013407	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
701347013408	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
701347013409	[4Fe-4S] binding site [ion binding]; other site
701347013410	molybdopterin cofactor binding site; other site
701347013411	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
701347013412	molybdopterin cofactor binding site; other site
701347013413	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
701347013414	Sel1-like repeats; Region: SEL1; smart00671
701347013415	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
701347013416	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
701347013417	acetyl-CoA synthetase; Provisional; Region: PRK00174
701347013418	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
701347013419	active site
701347013420	CoA binding site [chemical binding]; other site
701347013421	acyl-activating enzyme (AAE) consensus motif; other site
701347013422	AMP binding site [chemical binding]; other site
701347013423	acetate binding site [chemical binding]; other site
701347013424	Predicted membrane protein [Function unknown]; Region: COG3162
701347013425	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
701347013426	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
701347013427	Na binding site [ion binding]; other site
701347013428	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
701347013429	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
701347013430	Transcriptional regulator [Transcription]; Region: LysR; COG0583
701347013431	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347013432	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
701347013433	putative dimerization interface [polypeptide binding]; other site
701347013434	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
701347013435	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
701347013436	Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047
701347013437	Helix-Turn-Helix DNA binding domain of the CadR and PbrR transcription regulators; Region: HTH_CadR-PbrR; cd04784
701347013438	DNA binding residues [nucleotide binding]
701347013439	dimer interface [polypeptide binding]; other site
701347013440	putative metal binding site [ion binding]; other site
701347013441	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
701347013442	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
701347013443	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
701347013444	Autotransporter beta-domain; Region: Autotransporter; pfam03797
701347013445	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
701347013446	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
701347013447	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
701347013448	DNA binding residues [nucleotide binding]
701347013449	dimer interface [polypeptide binding]; other site
701347013450	[2Fe-2S] cluster binding site [ion binding]; other site
701347013451	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
701347013452	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347013453	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
701347013454	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
701347013455	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347013456	Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein [Cell envelope biogenesis, outer membrane]; Region: COG4623
701347013457	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347013458	substrate binding pocket [chemical binding]; other site
701347013459	membrane-bound complex binding site; other site
701347013460	hinge residues; other site
701347013461	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
701347013462	N-acetyl-D-glucosamine binding site [chemical binding]; other site
701347013463	catalytic residue [active]
701347013464	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
701347013465	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
701347013466	active site
701347013467	trimer interface [polypeptide binding]; other site
701347013468	allosteric site; other site
701347013469	active site lid [active]
701347013470	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
701347013471	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347013472	DNA-binding site [nucleotide binding]; DNA binding site
701347013473	UTRA domain; Region: UTRA; pfam07702
701347013474	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
701347013475	active pocket/dimerization site; other site
701347013476	active site
701347013477	phosphorylation site [posttranslational modification]
701347013478	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
701347013479	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
701347013480	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
701347013481	active site
701347013482	phosphorylation site [posttranslational modification]
701347013483	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
701347013484	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
701347013485	dimer interface [polypeptide binding]; other site
701347013486	ssDNA binding site [nucleotide binding]; other site
701347013487	tetramer (dimer of dimers) interface [polypeptide binding]; other site
701347013488	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
701347013489	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
701347013490	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
701347013491	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
701347013492	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
701347013493	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
701347013494	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347013495	active site
701347013496	motif I; other site
701347013497	motif II; other site
701347013498	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
701347013499	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
701347013500	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347013501	homodimer interface [polypeptide binding]; other site
701347013502	catalytic residue [active]
701347013503	alanine racemase; Reviewed; Region: alr; PRK00053
701347013504	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
701347013505	active site
701347013506	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
701347013507	substrate binding site [chemical binding]; other site
701347013508	catalytic residues [active]
701347013509	dimer interface [polypeptide binding]; other site
701347013510	replicative DNA helicase; Provisional; Region: PRK08006
701347013511	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
701347013512	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
701347013513	Walker A motif; other site
701347013514	ATP binding site [chemical binding]; other site
701347013515	Walker B motif; other site
701347013516	DNA binding loops [nucleotide binding]
701347013517	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
701347013518	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
701347013519	NADP binding site [chemical binding]; other site
701347013520	dimer interface [polypeptide binding]; other site
701347013521	phage shock protein G; Reviewed; Region: pspG; PRK09459
701347013522	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
701347013523	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
701347013524	FMN binding site [chemical binding]; other site
701347013525	active site
701347013526	catalytic residues [active]
701347013527	substrate binding site [chemical binding]; other site
701347013528	Cupin domain; Region: Cupin_2; cl17218
701347013529	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
701347013530	metal binding site 2 [ion binding]; metal-binding site
701347013531	putative DNA binding helix; other site
701347013532	metal binding site 1 [ion binding]; metal-binding site
701347013533	dimer interface [polypeptide binding]; other site
701347013534	structural Zn2+ binding site [ion binding]; other site
701347013535	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
701347013536	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
701347013537	LexA repressor; Validated; Region: PRK00215
701347013538	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
701347013539	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
701347013540	Catalytic site [active]
701347013541	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
701347013542	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
701347013543	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
701347013544	putative acyl-acceptor binding pocket; other site
701347013545	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
701347013546	UbiA prenyltransferase family; Region: UbiA; pfam01040
701347013547	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
701347013548	maltose regulon periplasmic protein; Provisional; Region: PRK10564
701347013549	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
701347013550	trimer interface; other site
701347013551	sugar binding site [chemical binding]; other site
701347013552	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
701347013553	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
701347013554	Walker A/P-loop; other site
701347013555	ATP binding site [chemical binding]; other site
701347013556	Q-loop/lid; other site
701347013557	ABC transporter signature motif; other site
701347013558	Walker B; other site
701347013559	D-loop; other site
701347013560	H-loop/switch region; other site
701347013561	TOBE domain; Region: TOBE_2; pfam08402
701347013562	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
701347013563	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
701347013564	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
701347013565	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347013566	dimer interface [polypeptide binding]; other site
701347013567	conserved gate region; other site
701347013568	putative PBP binding loops; other site
701347013569	ABC-ATPase subunit interface; other site
701347013570	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
701347013571	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347013572	dimer interface [polypeptide binding]; other site
701347013573	conserved gate region; other site
701347013574	putative PBP binding loops; other site
701347013575	ABC-ATPase subunit interface; other site
701347013576	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
701347013577	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
701347013578	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
701347013579	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
701347013580	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
701347013581	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
701347013582	active site
701347013583	dimer interface [polypeptide binding]; other site
701347013584	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
701347013585	dimer interface [polypeptide binding]; other site
701347013586	active site
701347013587	aspartate kinase III; Validated; Region: PRK09084
701347013588	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
701347013589	nucleotide binding site [chemical binding]; other site
701347013590	putative catalytic residues [active]
701347013591	aspartate binding site [chemical binding]; other site
701347013592	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
701347013593	lysine allosteric regulatory site; other site
701347013594	dimer interface [polypeptide binding]; other site
701347013595	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
701347013596	dimer interface [polypeptide binding]; other site
701347013597	hypothetical protein; Provisional; Region: PRK10515
701347013598	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
701347013599	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
701347013600	RNA binding surface [nucleotide binding]; other site
701347013601	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
701347013602	probable active site [active]
701347013603	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
701347013604	active site pocket [active]
701347013605	oxyanion hole [active]
701347013606	catalytic triad [active]
701347013607	active site nucleophile [active]
701347013608	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
701347013609	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
701347013610	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
701347013611	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
701347013612	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
701347013613	substrate binding pocket [chemical binding]; other site
701347013614	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
701347013615	B12 binding site [chemical binding]; other site
701347013616	cobalt ligand [ion binding]; other site
701347013617	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
701347013618	transcriptional repressor IclR; Provisional; Region: PRK11569
701347013619	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
701347013620	Bacterial transcriptional regulator; Region: IclR; pfam01614
701347013621	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
701347013622	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
701347013623	isocitrate lyase; Provisional; Region: PRK15063
701347013624	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
701347013625	tetramer interface [polypeptide binding]; other site
701347013626	active site
701347013627	Mg2+/Mn2+ binding site [ion binding]; other site
701347013628	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
701347013629	malate synthase A; Region: malate_syn_A; TIGR01344
701347013630	active site
701347013631	homoserine O-succinyltransferase; Provisional; Region: PRK05368
701347013632	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
701347013633	proposed active site lysine [active]
701347013634	conserved cys residue [active]
701347013635	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
701347013636	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
701347013637	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
701347013638	purine monophosphate binding site [chemical binding]; other site
701347013639	dimer interface [polypeptide binding]; other site
701347013640	putative catalytic residues [active]
701347013641	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
701347013642	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
701347013643	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
701347013644	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
701347013645	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
701347013646	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
701347013647	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
701347013648	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347013649	active site
701347013650	phosphorylation site [posttranslational modification]
701347013651	intermolecular recognition site; other site
701347013652	dimerization interface [polypeptide binding]; other site
701347013653	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347013654	Walker A motif; other site
701347013655	ATP binding site [chemical binding]; other site
701347013656	Walker B motif; other site
701347013657	arginine finger; other site
701347013658	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347013659	sensor protein ZraS; Provisional; Region: PRK10364
701347013660	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347013661	dimer interface [polypeptide binding]; other site
701347013662	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347013663	ATP binding site [chemical binding]; other site
701347013664	Mg2+ binding site [ion binding]; other site
701347013665	G-X-G motif; other site
701347013666	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
701347013667	dimer interface [polypeptide binding]; other site
701347013668	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
701347013669	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
701347013670	IHF dimer interface [polypeptide binding]; other site
701347013671	IHF - DNA interface [nucleotide binding]; other site
701347013672	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
701347013673	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
701347013674	Active_site [active]
701347013675	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
701347013676	substrate binding site [chemical binding]; other site
701347013677	active site
701347013678	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
701347013679	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
701347013680	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
701347013681	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
701347013682	putative NADH binding site [chemical binding]; other site
701347013683	putative active site [active]
701347013684	nudix motif; other site
701347013685	putative metal binding site [ion binding]; other site
701347013686	anti-RNA polymerase sigma 70 factor; Provisional; Region: PRK11718
701347013687	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
701347013688	ThiC-associated domain; Region: ThiC-associated; pfam13667
701347013689	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
701347013690	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
701347013691	thiamine phosphate binding site [chemical binding]; other site
701347013692	active site
701347013693	pyrophosphate binding site [ion binding]; other site
701347013694	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
701347013695	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
701347013696	ATP binding site [chemical binding]; other site
701347013697	substrate interface [chemical binding]; other site
701347013698	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
701347013699	thiS-thiF/thiG interaction site; other site
701347013700	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
701347013701	ThiS interaction site; other site
701347013702	putative active site [active]
701347013703	tetramer interface [polypeptide binding]; other site
701347013704	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
701347013705	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347013706	FeS/SAM binding site; other site
701347013707	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
701347013708	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
701347013709	active site
701347013710	P-loop; other site
701347013711	phosphorylation site [posttranslational modification]
701347013712	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
701347013713	methionine cluster; other site
701347013714	active site
701347013715	phosphorylation site [posttranslational modification]
701347013716	metal binding site [ion binding]; metal-binding site
701347013717	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347013718	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347013719	TM-ABC transporter signature motif; other site
701347013720	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
701347013721	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347013722	Walker A/P-loop; other site
701347013723	ATP binding site [chemical binding]; other site
701347013724	Q-loop/lid; other site
701347013725	ABC transporter signature motif; other site
701347013726	Walker B; other site
701347013727	D-loop; other site
701347013728	H-loop/switch region; other site
701347013729	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347013730	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
701347013731	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
701347013732	ligand binding site [chemical binding]; other site
701347013733	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
701347013734	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
701347013735	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
701347013736	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
701347013737	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
701347013738	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
701347013739	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
701347013740	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
701347013741	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
701347013742	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
701347013743	DNA binding site [nucleotide binding]
701347013744	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
701347013745	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
701347013746	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
701347013747	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
701347013748	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
701347013749	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
701347013750	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
701347013751	RPB3 interaction site [polypeptide binding]; other site
701347013752	RPB1 interaction site [polypeptide binding]; other site
701347013753	RPB11 interaction site [polypeptide binding]; other site
701347013754	RPB10 interaction site [polypeptide binding]; other site
701347013755	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
701347013756	23S rRNA interface [nucleotide binding]; other site
701347013757	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
701347013758	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
701347013759	mRNA/rRNA interface [nucleotide binding]; other site
701347013760	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
701347013761	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
701347013762	23S rRNA interface [nucleotide binding]; other site
701347013763	L7/L12 interface [polypeptide binding]; other site
701347013764	putative thiostrepton binding site; other site
701347013765	L25 interface [polypeptide binding]; other site
701347013766	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
701347013767	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
701347013768	putative homodimer interface [polypeptide binding]; other site
701347013769	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
701347013770	heterodimer interface [polypeptide binding]; other site
701347013771	homodimer interface [polypeptide binding]; other site
701347013772	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
701347013773	elongation factor Tu; Reviewed; Region: PRK00049
701347013774	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
701347013775	G1 box; other site
701347013776	GEF interaction site [polypeptide binding]; other site
701347013777	GTP/Mg2+ binding site [chemical binding]; other site
701347013778	Switch I region; other site
701347013779	G2 box; other site
701347013780	G3 box; other site
701347013781	Switch II region; other site
701347013782	G4 box; other site
701347013783	G5 box; other site
701347013784	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
701347013785	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
701347013786	Antibiotic Binding Site [chemical binding]; other site
701347013787	pantothenate kinase; Provisional; Region: PRK05439
701347013788	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
701347013789	ATP-binding site [chemical binding]; other site
701347013790	CoA-binding site [chemical binding]; other site
701347013791	Mg2+-binding site [ion binding]; other site
701347013792	Biotin operon repressor [Transcription]; Region: BirA; COG1654
701347013793	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
701347013794	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
701347013795	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
701347013796	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
701347013797	FAD binding domain; Region: FAD_binding_4; pfam01565
701347013798	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
701347013799	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
701347013800	potassium transporter; Provisional; Region: PRK10750
701347013801	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
701347013802	hypothetical protein; Provisional; Region: PRK11568
701347013803	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
701347013804	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
701347013805	proline dipeptidase; Provisional; Region: PRK13607
701347013806	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
701347013807	active site
701347013808	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
701347013809	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
701347013810	substrate binding site [chemical binding]; other site
701347013811	oxyanion hole (OAH) forming residues; other site
701347013812	trimer interface [polypeptide binding]; other site
701347013813	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
701347013814	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
701347013815	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
701347013816	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
701347013817	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
701347013818	dimer interface [polypeptide binding]; other site
701347013819	active site
701347013820	FMN reductase; Validated; Region: fre; PRK08051
701347013821	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
701347013822	FAD binding pocket [chemical binding]; other site
701347013823	FAD binding motif [chemical binding]; other site
701347013824	phosphate binding motif [ion binding]; other site
701347013825	beta-alpha-beta structure motif; other site
701347013826	NAD binding pocket [chemical binding]; other site
701347013827	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
701347013828	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
701347013829	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
701347013830	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
701347013831	active site
701347013832	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
701347013833	sec-independent translocase; Provisional; Region: PRK01770
701347013834	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
701347013835	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
701347013836	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
701347013837	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
701347013838	SCP-2 sterol transfer family; Region: SCP2; pfam02036
701347013839	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
701347013840	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347013841	S-adenosylmethionine binding site [chemical binding]; other site
701347013842	DNA recombination protein RmuC; Provisional; Region: PRK10361
701347013843	RmuC family; Region: RmuC; pfam02646
701347013844	uridine phosphorylase; Provisional; Region: PRK11178
701347013845	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
701347013846	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
701347013847	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
701347013848	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
701347013849	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
701347013850	THF binding site; other site
701347013851	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
701347013852	substrate binding site [chemical binding]; other site
701347013853	THF binding site; other site
701347013854	zinc-binding site [ion binding]; other site
701347013855	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
701347013856	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347013857	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
701347013858	putative dimerization interface [polypeptide binding]; other site
701347013859	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
701347013860	EamA-like transporter family; Region: EamA; pfam00892
701347013861	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
701347013862	putative hydrolase; Provisional; Region: PRK10976
701347013863	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347013864	active site
701347013865	motif I; other site
701347013866	motif II; other site
701347013867	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
701347013868	lysophospholipase L2; Provisional; Region: PRK10749
701347013869	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
701347013870	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
701347013871	threonine efflux system; Provisional; Region: PRK10229
701347013872	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
701347013873	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347013874	ATP binding site [chemical binding]; other site
701347013875	putative Mg++ binding site [ion binding]; other site
701347013876	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347013877	nucleotide binding region [chemical binding]; other site
701347013878	ATP-binding site [chemical binding]; other site
701347013879	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
701347013880	Helicase and RNase D C-terminal; Region: HRDC; smart00341
701347013881	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
701347013882	dimerization interface [polypeptide binding]; other site
701347013883	substrate binding site [chemical binding]; other site
701347013884	active site
701347013885	calcium binding site [ion binding]; other site
701347013886	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
701347013887	CoenzymeA binding site [chemical binding]; other site
701347013888	subunit interaction site [polypeptide binding]; other site
701347013889	PHB binding site; other site
701347013890	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
701347013891	Fatty acid desaturase protein family subgroup, a delta-12 acyl-lipid desaturase-like, DesA-like, yet uncharacterized subgroup of membrane fatty acid desaturase proteins found in alpha-, beta-, and gamma-proteobacteria. Sequences of this domain family...; Region: DesA_FADS-like; cd03509
701347013892	putative di-iron ligands [ion binding]; other site
701347013893	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
701347013894	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
701347013895	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
701347013896	Cl binding site [ion binding]; other site
701347013897	oligomer interface [polypeptide binding]; other site
701347013898	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
701347013899	Part of AAA domain; Region: AAA_19; pfam13245
701347013900	Family description; Region: UvrD_C_2; pfam13538
701347013901	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
701347013902	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347013903	motif II; other site
701347013904	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
701347013905	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
701347013906	active site
701347013907	Int/Topo IB signature motif; other site
701347013908	hypothetical protein; Provisional; Region: PRK10963
701347013909	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
701347013910	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
701347013911	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
701347013912	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
701347013913	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
701347013914	putative iron binding site [ion binding]; other site
701347013915	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
701347013916	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
701347013917	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
701347013918	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
701347013919	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
701347013920	domain interfaces; other site
701347013921	active site
701347013922	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
701347013923	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
701347013924	active site
701347013925	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
701347013926	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
701347013927	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
701347013928	HemY protein N-terminus; Region: HemY_N; pfam07219
701347013929	putative transport protein YifK; Provisional; Region: PRK10746
701347013930	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
701347013931	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
701347013932	putative common antigen polymerase; Provisional; Region: PRK02975
701347013933	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
701347013934	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
701347013935	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
701347013936	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
701347013937	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
701347013938	inhibitor-cofactor binding pocket; inhibition site
701347013939	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347013940	catalytic residue [active]
701347013941	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
701347013942	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
701347013943	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
701347013944	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
701347013945	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
701347013946	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
701347013947	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
701347013948	homodimer interface [polypeptide binding]; other site
701347013949	active site
701347013950	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
701347013951	Chain length determinant protein; Region: Wzz; pfam02706
701347013952	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
701347013953	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
701347013954	Mg++ binding site [ion binding]; other site
701347013955	putative catalytic motif [active]
701347013956	substrate binding site [chemical binding]; other site
701347013957	transcription termination factor Rho; Provisional; Region: rho; PRK09376
701347013958	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
701347013959	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
701347013960	RNA binding site [nucleotide binding]; other site
701347013961	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
701347013962	multimer interface [polypeptide binding]; other site
701347013963	Walker A motif; other site
701347013964	ATP binding site [chemical binding]; other site
701347013965	Walker B motif; other site
701347013966	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
701347013967	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
701347013968	catalytic residues [active]
701347013969	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
701347013970	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
701347013971	ATP binding site [chemical binding]; other site
701347013972	Mg++ binding site [ion binding]; other site
701347013973	motif III; other site
701347013974	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
701347013975	nucleotide binding region [chemical binding]; other site
701347013976	ATP-binding site [chemical binding]; other site
701347013977	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
701347013978	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
701347013979	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
701347013980	Part of AAA domain; Region: AAA_19; pfam13245
701347013981	Family description; Region: UvrD_C_2; pfam13538
701347013982	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
701347013983	uridine phosphorylase; Provisional; Region: PRK11178
701347013984	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
701347013985	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
701347013986	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
701347013987	ligand binding site [chemical binding]; other site
701347013988	flexible hinge region; other site
701347013989	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
701347013990	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
701347013991	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
701347013992	ketol-acid reductoisomerase; Validated; Region: PRK05225
701347013993	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
701347013994	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
701347013995	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
701347013996	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347013997	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
701347013998	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
701347013999	putative dimerization interface [polypeptide binding]; other site
701347014000	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347014001	dimerization domain swap beta strand [polypeptide binding]; other site
701347014002	regulatory protein interface [polypeptide binding]; other site
701347014003	active site
701347014004	regulatory phosphorylation site [posttranslational modification]; other site
701347014005	DAK2 domain; Region: Dak2; cl03685
701347014006	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
701347014007	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
701347014008	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
701347014009	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases [Carbohydrate transport and metabolism]; Region: AraD; COG0235
701347014010	intersubunit interface [polypeptide binding]; other site
701347014011	active site
701347014012	Zn2+ binding site [ion binding]; other site
701347014013	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
701347014014	PRD domain; Region: PRD; pfam00874
701347014015	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
701347014016	active site
701347014017	P-loop; other site
701347014018	phosphorylation site [posttranslational modification]
701347014019	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
701347014020	active site
701347014021	phosphorylation site [posttranslational modification]
701347014022	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
701347014023	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
701347014024	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
701347014025	active site
701347014026	P-loop; other site
701347014027	phosphorylation site [posttranslational modification]
701347014028	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347014029	active site
701347014030	phosphorylation site [posttranslational modification]
701347014031	threonine dehydratase; Reviewed; Region: PRK09224
701347014032	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
701347014033	tetramer interface [polypeptide binding]; other site
701347014034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347014035	catalytic residue [active]
701347014036	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
701347014037	putative Ile/Val binding site [chemical binding]; other site
701347014038	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
701347014039	putative Ile/Val binding site [chemical binding]; other site
701347014040	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
701347014041	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
701347014042	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
701347014043	homodimer interface [polypeptide binding]; other site
701347014044	substrate-cofactor binding pocket; other site
701347014045	catalytic residue [active]
701347014046	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
701347014047	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
701347014048	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
701347014049	PYR/PP interface [polypeptide binding]; other site
701347014050	dimer interface [polypeptide binding]; other site
701347014051	TPP binding site [chemical binding]; other site
701347014052	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
701347014053	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
701347014054	TPP-binding site [chemical binding]; other site
701347014055	dimer interface [polypeptide binding]; other site
701347014056	putative ATP-dependent protease; Provisional; Region: PRK09862
701347014057	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
701347014058	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347014059	Walker A motif; other site
701347014060	ATP binding site [chemical binding]; other site
701347014061	Walker B motif; other site
701347014062	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
701347014063	hypothetical protein; Provisional; Region: PRK11027
701347014064	transcriptional regulator HdfR; Provisional; Region: PRK03601
701347014065	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347014066	LysR substrate binding domain; Region: LysR_substrate; pfam03466
701347014067	dimerization interface [polypeptide binding]; other site
701347014068	glutamate racemase; Provisional; Region: PRK00865
701347014069	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
701347014070	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
701347014071	N-terminal plug; other site
701347014072	ligand-binding site [chemical binding]; other site
701347014073	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
701347014074	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347014075	S-adenosylmethionine binding site [chemical binding]; other site
701347014076	The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family; Region: CHAD; smart00880
701347014077	hypothetical protein; Provisional; Region: PRK11056
701347014078	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
701347014079	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
701347014080	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
701347014081	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
701347014082	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
701347014083	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
701347014084	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347014085	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
701347014086	dimerization interface [polypeptide binding]; other site
701347014087	argininosuccinate lyase; Provisional; Region: PRK04833
701347014088	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
701347014089	active sites [active]
701347014090	tetramer interface [polypeptide binding]; other site
701347014091	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
701347014092	nucleotide binding site [chemical binding]; other site
701347014093	N-acetyl-L-glutamate binding site [chemical binding]; other site
701347014094	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
701347014095	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
701347014096	acetylornithine deacetylase; Provisional; Region: PRK05111
701347014097	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
701347014098	metal binding site [ion binding]; metal-binding site
701347014099	putative dimer interface [polypeptide binding]; other site
701347014100	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
701347014101	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
701347014102	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
701347014103	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347014104	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
701347014105	active site
701347014106	P-loop; other site
701347014107	phosphorylation site [posttranslational modification]
701347014108	pyruvate formate lyase II activase; Provisional; Region: PRK10076
701347014109	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
701347014110	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
701347014111	dimer interface [polypeptide binding]; other site
701347014112	active site
701347014113	glycine loop; other site
701347014114	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
701347014115	active site
701347014116	P-loop; other site
701347014117	phosphorylation site [posttranslational modification]
701347014118	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
701347014119	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
701347014120	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
701347014121	dimerization domain swap beta strand [polypeptide binding]; other site
701347014122	regulatory protein interface [polypeptide binding]; other site
701347014123	active site
701347014124	regulatory phosphorylation site [posttranslational modification]; other site
701347014125	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
701347014126	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
701347014127	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
701347014128	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
701347014129	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
701347014130	active site
701347014131	phosphorylation site [posttranslational modification]
701347014132	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
701347014133	active site
701347014134	intersubunit interactions; other site
701347014135	catalytic residue [active]
701347014136	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
701347014137	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
701347014138	dimer interface [polypeptide binding]; other site
701347014139	active site
701347014140	metal binding site [ion binding]; metal-binding site
701347014141	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
701347014142	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
701347014143	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
701347014144	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
701347014145	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
701347014146	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
701347014147	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347014148	FeS/SAM binding site; other site
701347014149	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
701347014150	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
701347014151	active site
701347014152	trimer interface [polypeptide binding]; other site
701347014153	allosteric site; other site
701347014154	active site lid [active]
701347014155	hexamer (dimer of trimers) interface [polypeptide binding]; other site
701347014156	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
701347014157	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
701347014158	active site
701347014159	dimer interface [polypeptide binding]; other site
701347014160	EamA-like transporter family; Region: EamA; pfam00892
701347014161	EamA-like transporter family; Region: EamA; pfam00892
701347014162	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
701347014163	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
701347014164	heme binding site [chemical binding]; other site
701347014165	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
701347014166	heme binding site [chemical binding]; other site
701347014167	Protein of unknown function (DUF2459); Region: DUF2459; cl09819
701347014168	Predicted membrane protein [Function unknown]; Region: COG3462
701347014169	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
701347014170	RelB antitoxin; Region: RelB; cl01171
701347014171	Protein of unknown function, DUF596; Region: DUF596; cl10492
701347014172	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
701347014173	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
701347014174	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
701347014175	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
701347014176	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
701347014177	FAD binding site [chemical binding]; other site
701347014178	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
701347014179	Nucleoside recognition; Region: Gate; pfam07670
701347014180	hypothetical protein; Provisional; Region: PRK10519
701347014181	isoaspartyl dipeptidase; Provisional; Region: PRK10657
701347014182	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
701347014183	active site
701347014184	cell density-dependent motility repressor; Provisional; Region: PRK10082
701347014185	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347014186	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
701347014187	dimerization interface [polypeptide binding]; other site
701347014188	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
701347014189	aspartate racemase; Region: asp_race; TIGR00035
701347014190	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
701347014191	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347014192	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
701347014193	dimerization interface [polypeptide binding]; other site
701347014194	substrate binding pocket [chemical binding]; other site
701347014195	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
701347014196	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
701347014197	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
701347014198	putative catalytic residues [active]
701347014199	putative nucleotide binding site [chemical binding]; other site
701347014200	putative aspartate binding site [chemical binding]; other site
701347014201	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
701347014202	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
701347014203	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
701347014204	cystathionine gamma-synthase; Provisional; Region: PRK08045
701347014205	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
701347014206	homodimer interface [polypeptide binding]; other site
701347014207	substrate-cofactor binding pocket; other site
701347014208	pyridoxal 5'-phosphate binding site [chemical binding]; other site
701347014209	catalytic residue [active]
701347014210	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
701347014211	dimerization interface [polypeptide binding]; other site
701347014212	DNA binding site [nucleotide binding]
701347014213	corepressor binding sites; other site
701347014214	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
701347014215	primosome assembly protein PriA; Validated; Region: PRK05580
701347014216	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
701347014217	ATP binding site [chemical binding]; other site
701347014218	putative Mg++ binding site [ion binding]; other site
701347014219	helicase superfamily c-terminal domain; Region: HELICc; smart00490
701347014220	ATP-binding site [chemical binding]; other site
701347014221	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347014222	DNA binding site [nucleotide binding]
701347014223	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
701347014224	domain linker motif; other site
701347014225	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
701347014226	dimerization interface [polypeptide binding]; other site
701347014227	ligand binding site [chemical binding]; other site
701347014228	cell division protein FtsN; Provisional; Region: PRK12757
701347014229	Sporulation related domain; Region: SPOR; cl10051
701347014230	Sporulation related domain; Region: SPOR; cl10051
701347014231	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
701347014232	active site
701347014233	HslU subunit interaction site [polypeptide binding]; other site
701347014234	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
701347014235	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347014236	Walker A motif; other site
701347014237	ATP binding site [chemical binding]; other site
701347014238	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
701347014239	Walker B motif; other site
701347014240	arginine finger; other site
701347014241	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
701347014242	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
701347014243	UbiA prenyltransferase family; Region: UbiA; pfam01040
701347014244	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
701347014245	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
701347014246	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
701347014247	active site
701347014248	ADP/pyrophosphate binding site [chemical binding]; other site
701347014249	dimerization interface [polypeptide binding]; other site
701347014250	allosteric effector site; other site
701347014251	fructose-1,6-bisphosphate binding site; other site
701347014252	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
701347014253	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
701347014254	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
701347014255	dimer interface [polypeptide binding]; other site
701347014256	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
701347014257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347014258	active site
701347014259	intermolecular recognition site; other site
701347014260	dimerization interface [polypeptide binding]; other site
701347014261	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
701347014262	DNA binding site [nucleotide binding]
701347014263	two-component sensor protein; Provisional; Region: cpxA; PRK09470
701347014264	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
701347014265	dimerization interface [polypeptide binding]; other site
701347014266	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347014267	dimer interface [polypeptide binding]; other site
701347014268	phosphorylation site [posttranslational modification]
701347014269	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347014270	ATP binding site [chemical binding]; other site
701347014271	Mg2+ binding site [ion binding]; other site
701347014272	G-X-G motif; other site
701347014273	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
701347014274	MOSC domain; Region: MOSC; pfam03473
701347014275	3-alpha domain; Region: 3-alpha; pfam03475
701347014276	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
701347014277	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
701347014278	inhibitor site; inhibition site
701347014279	active site
701347014280	dimer interface [polypeptide binding]; other site
701347014281	catalytic residue [active]
701347014282	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
701347014283	superoxide dismutase; Provisional; Region: PRK10925
701347014284	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
701347014285	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
701347014286	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
701347014287	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
701347014288	transcriptional activator RhaR; Provisional; Region: PRK13502
701347014289	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
701347014290	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347014291	transcriptional activator RhaS; Provisional; Region: PRK13503
701347014292	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
701347014293	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347014294	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
701347014295	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
701347014296	N- and C-terminal domain interface [polypeptide binding]; other site
701347014297	active site
701347014298	putative catalytic site [active]
701347014299	metal binding site [ion binding]; metal-binding site
701347014300	ATP binding site [chemical binding]; other site
701347014301	rhamnulokinase; Provisional; Region: rhaB; PRK10640
701347014302	carbohydrate binding site [chemical binding]; other site
701347014303	L-rhamnose isomerase; Provisional; Region: PRK01076
701347014304	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
701347014305	intersubunit interface [polypeptide binding]; other site
701347014306	active site
701347014307	Zn2+ binding site [ion binding]; other site
701347014308	Domain of unknown function (DUF718); Region: DUF718; cl01281
701347014309	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
701347014310	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
701347014311	non-specific DNA binding site [nucleotide binding]; other site
701347014312	salt bridge; other site
701347014313	sequence-specific DNA binding site [nucleotide binding]; other site
701347014314	Cupin domain; Region: Cupin_2; cl17218
701347014315	AzlC protein; Region: AzlC; cl00570
701347014316	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
701347014317	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
701347014318	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347014319	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
701347014320	molybdopterin cofactor binding site; other site
701347014321	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
701347014322	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
701347014323	molybdopterin cofactor binding site; other site
701347014324	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
701347014325	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
701347014326	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
701347014327	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
701347014328	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
701347014329	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
701347014330	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
701347014331	oligomeric interface; other site
701347014332	putative active site [active]
701347014333	homodimer interface [polypeptide binding]; other site
701347014334	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
701347014335	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
701347014336	Coenzyme A binding pocket [chemical binding]; other site
701347014337	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
701347014338	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
701347014339	putative active site [active]
701347014340	dimerization interface [polypeptide binding]; other site
701347014341	putative tRNAtyr binding site [nucleotide binding]; other site
701347014342	hypothetical protein; Reviewed; Region: PRK01637
701347014343	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
701347014344	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347014345	motif II; other site
701347014346	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
701347014347	DNA binding residues [nucleotide binding]
701347014348	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
701347014349	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
701347014350	Autotransporter beta-domain; Region: Autotransporter; pfam03797
701347014351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347014352	putative substrate translocation pore; other site
701347014353	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
701347014354	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
701347014355	transcriptional regulator protein; Region: phnR; TIGR03337
701347014356	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347014357	DNA-binding site [nucleotide binding]; DNA binding site
701347014358	UTRA domain; Region: UTRA; pfam07702
701347014359	GTP-binding protein; Provisional; Region: PRK10218
701347014360	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
701347014361	G1 box; other site
701347014362	putative GEF interaction site [polypeptide binding]; other site
701347014363	GTP/Mg2+ binding site [chemical binding]; other site
701347014364	Switch I region; other site
701347014365	G2 box; other site
701347014366	G3 box; other site
701347014367	Switch II region; other site
701347014368	G4 box; other site
701347014369	G5 box; other site
701347014370	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
701347014371	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
701347014372	glutamine synthetase; Provisional; Region: glnA; PRK09469
701347014373	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
701347014374	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
701347014375	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
701347014376	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
701347014377	putative active site [active]
701347014378	heme pocket [chemical binding]; other site
701347014379	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
701347014380	dimer interface [polypeptide binding]; other site
701347014381	phosphorylation site [posttranslational modification]
701347014382	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
701347014383	ATP binding site [chemical binding]; other site
701347014384	Mg2+ binding site [ion binding]; other site
701347014385	G-X-G motif; other site
701347014386	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
701347014387	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
701347014388	active site
701347014389	phosphorylation site [posttranslational modification]
701347014390	intermolecular recognition site; other site
701347014391	dimerization interface [polypeptide binding]; other site
701347014392	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347014393	Walker A motif; other site
701347014394	ATP binding site [chemical binding]; other site
701347014395	Walker B motif; other site
701347014396	arginine finger; other site
701347014397	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
701347014398	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
701347014399	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
701347014400	FeS/SAM binding site; other site
701347014401	HemN C-terminal domain; Region: HemN_C; pfam06969
701347014402	Der GTPase activator; Provisional; Region: PRK05244
701347014403	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
701347014404	G1 box; other site
701347014405	GTP/Mg2+ binding site [chemical binding]; other site
701347014406	Switch I region; other site
701347014407	G2 box; other site
701347014408	G3 box; other site
701347014409	Switch II region; other site
701347014410	G4 box; other site
701347014411	G5 box; other site
701347014412	DNA polymerase I; Provisional; Region: PRK05755
701347014413	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
701347014414	active site
701347014415	metal binding site 1 [ion binding]; metal-binding site
701347014416	putative 5' ssDNA interaction site; other site
701347014417	metal binding site 3; metal-binding site
701347014418	metal binding site 2 [ion binding]; metal-binding site
701347014419	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
701347014420	putative DNA binding site [nucleotide binding]; other site
701347014421	putative metal binding site [ion binding]; other site
701347014422	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
701347014423	active site
701347014424	catalytic site [active]
701347014425	substrate binding site [chemical binding]; other site
701347014426	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
701347014427	active site
701347014428	DNA binding site [nucleotide binding]
701347014429	catalytic site [active]
701347014430	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
701347014431	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
701347014432	putative acyl-acceptor binding pocket; other site
701347014433	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
701347014434	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
701347014435	catalytic residues [active]
701347014436	hinge region; other site
701347014437	alpha helical domain; other site
701347014438	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
701347014439	serine/threonine protein kinase; Provisional; Region: PRK11768
701347014440	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
701347014441	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
701347014442	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
701347014443	GTP binding site; other site
701347014444	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
701347014445	Walker A motif; other site
701347014446	Transcriptional regulators [Transcription]; Region: GntR; COG1802
701347014447	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
701347014448	DNA-binding site [nucleotide binding]; DNA binding site
701347014449	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
701347014450	putative transporter; Provisional; Region: PRK10504
701347014451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347014452	putative substrate translocation pore; other site
701347014453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347014454	transcriptional repressor RbsR; Provisional; Region: PRK10423
701347014455	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
701347014456	DNA binding site [nucleotide binding]
701347014457	domain linker motif; other site
701347014458	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
701347014459	dimerization interface [polypeptide binding]; other site
701347014460	ligand binding site [chemical binding]; other site
701347014461	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
701347014462	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
701347014463	substrate binding site [chemical binding]; other site
701347014464	dimer interface [polypeptide binding]; other site
701347014465	ATP binding site [chemical binding]; other site
701347014466	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
701347014467	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
701347014468	ligand binding site [chemical binding]; other site
701347014469	dimerization interface [polypeptide binding]; other site
701347014470	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
701347014471	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
701347014472	TM-ABC transporter signature motif; other site
701347014473	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
701347014474	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
701347014475	Walker A/P-loop; other site
701347014476	ATP binding site [chemical binding]; other site
701347014477	Q-loop/lid; other site
701347014478	ABC transporter signature motif; other site
701347014479	Walker B; other site
701347014480	D-loop; other site
701347014481	H-loop/switch region; other site
701347014482	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
701347014483	D-ribose pyranase; Provisional; Region: PRK11797
701347014484	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
701347014485	potassium uptake protein; Region: kup; TIGR00794
701347014486	regulatory ATPase RavA; Provisional; Region: PRK13531
701347014487	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
701347014488	Walker A motif; other site
701347014489	ATP binding site [chemical binding]; other site
701347014490	Walker B motif; other site
701347014491	arginine finger; other site
701347014492	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
701347014493	hypothetical protein; Provisional; Region: yieM; PRK10997
701347014494	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
701347014495	metal ion-dependent adhesion site (MIDAS); other site
701347014496	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
701347014497	dimer interface [polypeptide binding]; other site
701347014498	active site
701347014499	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
701347014500	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
701347014501	putative DNA binding site [nucleotide binding]; other site
701347014502	putative Zn2+ binding site [ion binding]; other site
701347014503	AsnC family; Region: AsnC_trans_reg; pfam01037
701347014504	FMN-binding protein MioC; Provisional; Region: PRK09004
701347014505	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
701347014506	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
701347014507	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
701347014508	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
701347014509	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
701347014510	S-adenosylmethionine binding site [chemical binding]; other site
701347014511	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
701347014512	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
701347014513	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
701347014514	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
701347014515	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
701347014516	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
701347014517	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
701347014518	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
701347014519	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
701347014520	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
701347014521	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
701347014522	beta subunit interaction interface [polypeptide binding]; other site
701347014523	Walker A motif; other site
701347014524	ATP binding site [chemical binding]; other site
701347014525	Walker B motif; other site
701347014526	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
701347014527	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
701347014528	core domain interface [polypeptide binding]; other site
701347014529	delta subunit interface [polypeptide binding]; other site
701347014530	epsilon subunit interface [polypeptide binding]; other site
701347014531	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
701347014532	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
701347014533	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
701347014534	alpha subunit interaction interface [polypeptide binding]; other site
701347014535	Walker A motif; other site
701347014536	ATP binding site [chemical binding]; other site
701347014537	Walker B motif; other site
701347014538	inhibitor binding site; inhibition site
701347014539	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
701347014540	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
701347014541	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
701347014542	gamma subunit interface [polypeptide binding]; other site
701347014543	epsilon subunit interface [polypeptide binding]; other site
701347014544	LBP interface [polypeptide binding]; other site
701347014545	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
701347014546	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
701347014547	Substrate binding site; other site
701347014548	Mg++ binding site; other site
701347014549	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
701347014550	active site
701347014551	substrate binding site [chemical binding]; other site
701347014552	CoA binding site [chemical binding]; other site
701347014553	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
701347014554	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
701347014555	glutaminase active site [active]
701347014556	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
701347014557	dimer interface [polypeptide binding]; other site
701347014558	active site
701347014559	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
701347014560	dimer interface [polypeptide binding]; other site
701347014561	active site
701347014562	Fimbrial protein; Region: Fimbrial; cl01416
701347014563	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
701347014564	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
701347014565	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
701347014566	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
701347014567	PapC N-terminal domain; Region: PapC_N; pfam13954
701347014568	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
701347014569	PapC C-terminal domain; Region: PapC_C; pfam13953
701347014570	Fimbrial protein; Region: Fimbrial; cl01416
701347014571	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
701347014572	substrate binding pocket [chemical binding]; other site
701347014573	membrane-bound complex binding site; other site
701347014574	hinge residues; other site
701347014575	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
701347014576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347014577	dimer interface [polypeptide binding]; other site
701347014578	conserved gate region; other site
701347014579	putative PBP binding loops; other site
701347014580	ABC-ATPase subunit interface; other site
701347014581	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
701347014582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
701347014583	dimer interface [polypeptide binding]; other site
701347014584	conserved gate region; other site
701347014585	putative PBP binding loops; other site
701347014586	ABC-ATPase subunit interface; other site
701347014587	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
701347014588	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
701347014589	Walker A/P-loop; other site
701347014590	ATP binding site [chemical binding]; other site
701347014591	Q-loop/lid; other site
701347014592	ABC transporter signature motif; other site
701347014593	Walker B; other site
701347014594	D-loop; other site
701347014595	H-loop/switch region; other site
701347014596	transcriptional regulator PhoU; Provisional; Region: PRK11115
701347014597	PhoU domain; Region: PhoU; pfam01895
701347014598	PhoU domain; Region: PhoU; pfam01895
701347014599	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
701347014600	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
701347014601	active site
701347014602	motif I; other site
701347014603	motif II; other site
701347014604	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
701347014605	Predicted flavoprotein [General function prediction only]; Region: COG0431
701347014606	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
701347014607	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
701347014608	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
701347014609	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
701347014610	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
701347014611	substrate binding pocket [chemical binding]; other site
701347014612	dimerization interface [polypeptide binding]; other site
701347014613	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
701347014614	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
701347014615	putative substrate translocation pore; other site
701347014616	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
701347014617	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
701347014618	metal binding site [ion binding]; metal-binding site
701347014619	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
701347014620	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
701347014621	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
701347014622	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347014623	ABC-ATPase subunit  interface; other site
701347014624	dimer interface [polypeptide binding]; other site
701347014625	putative PBP binding regions; other site
701347014626	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
701347014627	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
701347014628	ABC-ATPase subunit  interface; other site
701347014629	dimer interface [polypeptide binding]; other site
701347014630	putative PBP binding regions; other site
701347014631	RibD C-terminal domain; Region: RibD_C; cl17279
701347014632	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
701347014633	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
701347014634	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
701347014635	trmE is a tRNA modification GTPase; Region: trmE; cd04164
701347014636	G1 box; other site
701347014637	GTP/Mg2+ binding site [chemical binding]; other site
701347014638	Switch I region; other site
701347014639	G2 box; other site
701347014640	Switch II region; other site
701347014641	G3 box; other site
701347014642	G4 box; other site
701347014643	G5 box; other site
701347014644	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
701347014645	membrane protein insertase; Provisional; Region: PRK01318
701347014646	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
701347014647	hypothetical protein; Validated; Region: PRK00041
701347014648	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399